WorldWideScience

Sample records for caverns

  1. ATLAS Cavern baseplate

    CERN Multimedia

    2002-01-01

    This video shows the incredible amounth of iron used for ATLAS cavern. Please look at the related links and also videos that are concerning the civil engineering where you can see even more detailed cavern excavation work.

  2. Intramuscular cavernous hemangioma.

    Science.gov (United States)

    Melman, Lora; Johnson, Frank E

    2008-06-01

    Intramuscular cavernous hemagiomas represent <1% of all hemangiomas and consist of benign proliferations of blood vessels. Typical presentation is an enlarging painful soft-tissue mass without cutaneous changes. Intramuscular cavernous hemangiomas do not undergo spontaneous regression and may be locally destructive because pressure is exerted on neighboring structures. Phleboliths on radiograph are a specific finding for cavernous hemangioma. Definitive treatment of this condition is surgical excision. PMID:18440488

  3. About Cavernous Angioma

    Science.gov (United States)

    ... Imaging Symptoms and Treatment Brainstem Cavernous Angiomas Central Pain Syndrome Epilepsy Hemorrhage Radiosurgery Venous Angioma/DVA Surgery Preparing for Surgery Things for the Hospital Caregiver Information Emotional Support Rehabilitation Brain Health Types of ...

  4. Cavernous Angioma and Children

    Science.gov (United States)

    ... Canoeing – Wear a life vest and helmet Caving Golf Ice-skating or hockey – Wear a helmet Boxing ... emergency. Cavernous malformations may play a role in learning or behavior problems a child might experience. Knowing ...

  5. Extradural lumbosacral cavernous hemangioma

    OpenAIRE

    Tekkök, Ismail H.; Akpınar, Gökhan; Güngen, Yücel

    2003-01-01

    Purely extradural cavernous hemangiomas of the spinal canal are extremely rare. Their occurrence at the lumbosacral level is a true exception. We describe a case of lumbosacral extradural hemangioma and review the behaviour and MR imaging characteristics of these lesions. Cavernous hemangioma should be considered in the differential diagnosis of an enhancing extradural periradicular mass causing chronic lumbar radiculopathy especially in fertile women. Lumbar extradural hemangiomas appear and...

  6. Study of mined storage caverns

    International Nuclear Information System (INIS)

    All available information concerning 75 mined storage caverns as well as the investigative techniques utilized to determine the feasibility of a cavern site is presented. Potential new storage caverns may be for products such as high or low vapor pressure petroleum products, other chemical products, aid industrial or nuclear waste

  7. Penile cavernous hemangioma

    Directory of Open Access Journals (Sweden)

    Abdelmoughit ECHCHAOUI

    2015-06-01

    Full Text Available Hemangiomas are benign lesions that occur in any part of the body in newborns or in young patients, they are typically capillary or cavernous. Cavernous hemangioma of the penis is extremely rare; and its etiology is not completely understood. Treatment options (surgical excision, laser therapy or sclerotherapy… are controversial and are required if pain, cosmetic defect and/or bleeding during intercourse.                                                  We report a case of a 26 years old man presented with a five years history of a painless lesion on his penis. Physical examination showed an ovoid, solid, 1 x 2 mm in size on the dorsum of penis (Panel A and two elevated irregular lesions on the ventral side (Panel B. The lesions were compressive, nonpulsatile and bluish-red in color with strawberry like appearance. Biopsy and histopathological examination of the lesion revealed a gaping and communicating vessels proliferated in the superficial and medium dermis which is pathognomonic for cavernous hemangioma (Panel C and D. Given the small size, the large number of the lesions, the young age, and the ulceration risk during intercourse if skin graft after excision, Neodymium: YAG laser coagulation was recommended to get a good cosmetic results and sexual function satisfaction.

  8. Giant Cardiac Cavernous Hemangioma.

    Science.gov (United States)

    Unger, Eric; Costic, Joseph; Laub, Glenn

    2015-07-01

    We report the case of an asymptomatic giant cardiac cavernous hemangioma in a 71-year-old man. The intracardiac mass was discovered incidentally during surveillance for his prostate cancer; however, the patient initially declined intervention. On presentation to our institution 7 years later, the lesion had enlarged significantly, and the patient consented to excision. At surgery, an 8 × 6.5 × 4.8 cm intracardiac mass located on the inferior heart border was excised with an intact capsule through a median sternotomy approach. The patient had an uneventful postoperative course. We discuss the diagnostic workup, treatment, and characteristics of this rare cardiac tumor. PMID:26140782

  9. Caverns for neutrino physicists

    International Nuclear Information System (INIS)

    Since more than 20 years, particle physicists are using underground facilities to catch cosmic neutrinos and to get rid of other parasitic cosmic radiations. The observation of significant numbers of neutrinos requires the use of large volume caverns at important depths. This article presents such existing facilities in the US, France, Italy, UK, Spain, Japan (Kamioka), Russia and India and the different projects in competition for the setting up of a mega-ton detector with a volume of 1 million m3 of water (DUSEL project in the US, MEMPHYS project in France, Hyperkamiokande in Japan). Several suitable underground spaces are available in these countries (abandoned mines, tunnels) but each has its advantages and drawbacks in terms of rock mechanics, access and seismicity. (J.S.)

  10. Cavernous hemangioma of the liver

    International Nuclear Information System (INIS)

    A case of cavernous hemangioma of the liver is described. A bibliographic revision and the role of the various methods of image diagnosis (ultrasonography, computed tomography, angiography, scintiscanning, usual radiologic exams) of this lesion. (M.A.C.)

  11. ATLAS Cavern - Sainte-Barbe evening

    CERN Multimedia

    2002-01-01

    The December at cavern of ATLAS was full of surprises, while during the iron mounting and concrete work the cavern got its new purpose for being the restaurant under little while -Live music and happy people.

  12. The huge ATLAS cavern now fully excavated

    CERN Multimedia

    2002-01-01

    Excavation of the ATLAS cavern is now complete! At the end of two years' work involving a tremendous technical challenge, the civil engineering contractors have succeeded in digging out one of the biggest experimental caverns in the world. Bravo!

  13. Constructing the ATLAS experimental cavern

    CERN Multimedia

    Laurent Guiraud

    2001-01-01

    The huge cavern that will house the ATLAS experiment on the LHC at CERN is seen in these images during construction. The site, located 100 m underground near the France-Swiss border, has one of the longest underground spans ever built at 35 m. The 1380 square metre cavern that will hold the 46X25X25 cubic metre detector (the largest of its type in the world) requires its ceiling to be held by ground anchors installed from galleries excavated laterally from the access shafts.

  14. The ALICE cavern and solenoid

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    The ALICE experiment, one of the four major experiments of CERN's LHC project, will be housed in the cavern that once contained the L3 experiment at the LEP accelerator. The huge solenoid is the only remaining piece of the L3 experiment and will be used by ALICE.

  15. Earthquake observation at underground cavern

    International Nuclear Information System (INIS)

    The earthquake observation has been examined at a cylindrical type cavern hydroelectric power station of 15 m in diameter, 22 m in depth in rock mass in purpose of evaluating the earthquake resistance of semi-underground nuclear power plants. The behavior of the cylindrical cavern has been analysed by fourty-three observed seismic waves. And following results were obtained. (1) Ratios of cavern buttom maximum accelerations to cavern top maximum accelerations are concentrated in the range from 1/2 to 1. This shows that the accelerations are declined at underground. (2) The decline ratios of on-ground spectrum amplitude to the underground at the earthquakes of less than 100 km epicentral distance with shorter predominant periods are generally larger than these at the earthquakes of more than 100 km epicentral distance with longer predominant periods. (3) The peak periods of normalized response spectrum at underground tend to be longer as the epicentral distances are longer. This phenominons of underground are similar to the on-ground. (author)

  16. Civil engineering in the ATLAS cavern

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    Work continues in the cathedral-like cavern that will soon contain ATLAS, the largest particle detector of its type in the world. For such a huge detector, an equally giant cavern must be excavated 100 m underground. The roof must be held without any normal rests at the base; instead it will be supported by huge anchors embedded in concrete that will stop the roof from caving in, located in galleries above the cavern.

  17. EVOKED CAVERNOUS ACTIVITY: NEUROANATOMIC IMPLICATIONS

    OpenAIRE

    Yilmaz, Ugur; Vicars, Brenda; Yang, Claire C.

    2009-01-01

    We investigated the autonomic innervation of the penis by using evoked cavernous activity (ECA). We recruited 7 males with thoracic spinal cord injury (SCI) and sexual dysfunction and 6 males who were scheduled to have pelvic surgery (PS), specifically non-nerve-sparing radical cystoprostatectomy. In the PS subjects, ECA was performed both pre- and postoperatively. The left median nerve was electrically stimulated and ECA was recorded with two concentric electromyography needles placed into t...

  18. MR findings of septic cavernous sinus thrombosis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyeong Lae; Lee, Nam Joon; Lee, Jung Hee; Pyo, Hyeon Soon; Eo, Geun; Kim, Kyo Nam; Kim, Young Soon; Kim, Jang Min [Kwang Myung Sung Ae Hospital, Kwang Myung (Korea, Republic of); Lee, Don Young [Korea University Anam Hospital, Seoul (Korea, Republic of)

    2000-08-01

    To evaluate the MR findings of septic thrombosis of the cavernous sinus. Eleven MR images of six patients with septic cavernous sinus thrombosis obtained over a five-year period and proven clinically or radiologically were retrospectively reviewed. The contour and enhancement pattern of the cavernous sinus, changes in the internal carotid artery, orbit, pituitary gland and sphenoid sinus, and intracranial abnormalities were analyzed and compared with the findings of follow-up studies. In all six patients, contrast study revealed asymmetrical enlargement of the ipsilateral cavernous sinus and multiple irregular filling defects within it. Narrowing of the cavernous portion of the ipsilateral internal carotid artery was noted in five patients, upward displacement of the ipsilateral internal carotid artery in four, ipsilateral proptosis with engorgement of the superior ophthalmic vein in two, pituitary enlargement in five, and inflammatory change in the sphenoid sinus in six. Associated intracranial abnormalities included edema and enhancement in the meninx, temporal lobe, or pons adjacent to the cavernous sinus in four patients, hydrocephalus in one, and cerebral infarction in one. Follow-up MR imaging indicated that the extent of asymmetrical enlargement of the cavernous sinus, filling defects within it, as seen on contrast study, and enlarged pituitary glands had all decreased, without significant interval change. MR imaging is useful in the diagnosis of septic cavernous sinus thrombosis. Asymmetrical enlargement of the cavernous sinus, multiple irregular filling defect within it, as seen on contrast study, and changes in the internal carotid artery are characteristic findings. (author)

  19. MR findings of septic cavernous sinus thrombosis

    International Nuclear Information System (INIS)

    To evaluate the MR findings of septic thrombosis of the cavernous sinus. Eleven MR images of six patients with septic cavernous sinus thrombosis obtained over a five-year period and proven clinically or radiologically were retrospectively reviewed. The contour and enhancement pattern of the cavernous sinus, changes in the internal carotid artery, orbit, pituitary gland and sphenoid sinus, and intracranial abnormalities were analyzed and compared with the findings of follow-up studies. In all six patients, contrast study revealed asymmetrical enlargement of the ipsilateral cavernous sinus and multiple irregular filling defects within it. Narrowing of the cavernous portion of the ipsilateral internal carotid artery was noted in five patients, upward displacement of the ipsilateral internal carotid artery in four, ipsilateral proptosis with engorgement of the superior ophthalmic vein in two, pituitary enlargement in five, and inflammatory change in the sphenoid sinus in six. Associated intracranial abnormalities included edema and enhancement in the meninx, temporal lobe, or pons adjacent to the cavernous sinus in four patients, hydrocephalus in one, and cerebral infarction in one. Follow-up MR imaging indicated that the extent of asymmetrical enlargement of the cavernous sinus, filling defects within it, as seen on contrast study, and enlarged pituitary glands had all decreased, without significant interval change. MR imaging is useful in the diagnosis of septic cavernous sinus thrombosis. Asymmetrical enlargement of the cavernous sinus, multiple irregular filling defect within it, as seen on contrast study, and changes in the internal carotid artery are characteristic findings. (author)

  20. A 12-year cavern abandonment test

    Directory of Open Access Journals (Sweden)

    Brouard B.

    2010-06-01

    Full Text Available In 1997-1998, an abandonment test was performed in a 950-m deep, 8000-m3 salt cavern operated by GDF SUEZ at Etrez, France. In this relatively small brine-filled cavern, which had been kept idle for 15 years before the test, thermal equilibrium was reached. A special system was designed to monitor leaks, which proved to be exceedingly small. In these conditions, brine permeation and cavern creep closure are the only factors to play significant roles in pressure evolution. This test strongly suggested that obtaining an equilibrium pressure such that the effects of these two factors were exactly equal would be reached in the long term. Four years later, pressure monitoring in the closed cavern resumed. Pressure evolution during the 2002-2009 period confirmed that cavern brine pressure will remain constant and significantly smaller than geostatic pressure in the long term, precluding any risk of fracturing and brine seepage to the overburden layers.

  1. CAROTID CAVERNOUS FISTULA: A RARE CASE REPORT

    Directory of Open Access Journals (Sweden)

    Satish Prasad

    2015-01-01

    Full Text Available Carotico - cavernous fistula represent abnormal communication between the carotid circulation and the cavernous sinus. They can be classified as direct or indirect which are separate conditions with different aetiologies. Direct Carotico - cavernous fistulas ( CCFs are often secondary to trauma, and as such the demographics reflect the distribution of head trauma, most commonly seen in the young male patients. Presentation is acute and symptoms develop rapidly. In contrast, indirect CCFs have a predilection for the postmenopausal female patient a nd the onset of symptoms is often insiduous. Other conditions that predispose to increased risk include . Ehlers - Danlos syndrome . Fibromuscular dysplasia .

  2. ATLAS cavern magnetic field calculations

    International Nuclear Information System (INIS)

    A new approach has been adopted in an attempt to produce a complete ATLAS cavern B-field map using a more precise methodological approach (variable magnetisation, depending on the external field) and the latest design taking into account of the structural elements. The basic idea was to produce a dedicated basic TOSCA model and then to insert a series of ferromagnetic structure elements to monitor the perturbative effect on the basic field map. Eventually, it was found: the bedplate field perturbation is an order of magnitude above the permissible level; manufacturing of the bedplates from nonmagnetic material or careful evaluation of their field contribution in the event reconstruction codes is required; the field value at the rack positions is higher than the permissible one; the final position of racks should be chosen taking into account the detailed magnetic field distribution

  3. Fungal infections and cavernous sinus thrombosis

    OpenAIRE

    Munjal, Manish; Khurana, A. S.

    2004-01-01

    Rhino — Cerebral Mucormycosis, in uncontrolled diabetics, is a common entity Cavernous Sinus Thrombosis, secondary to fungal involvement is rarely encountered Two cases with fulminant spread are reported highlighting the symptoms, signs, and therapeutic modality

  4. Transient behaviour of deep underground salt caverns

    International Nuclear Information System (INIS)

    This work deals with the transient behaviour of deep underground salt caverns. It has been shown that a cavern is a complex system, in which there are mechanical, thermal, chemical and hydraulic evolutions. The importance of the transient evolutions, particularly the role of the 'reverse' creep in the interpretation of the tightness test in a salt cavern is revealed. Creep is characterized by a formulation of the behaviour law which presents the advantage, in a practical point of view, to only have a reduced number of parameters while accounting of the essential of what it is observed. The initiation of the rupture in the effective traction in a salt cavern rapidly pressurized is discussed. A model fitted to a very long term behaviour (after abandonment) is developed too. In this case too, a lot of phenomena, more or less coupled, occur, when the existing literature took only into account some phenomena. (O.M.)

  5. Digging a cavern for a titan

    CERN Multimedia

    Patrice Loiez

    1999-01-01

    Civil engineers work 100 m underground near the France-Swiss border on the cavern that will soon house ATLAS, one of the experiments on CERN's new LHC accelerator. All personnel and equipment must be lowered by crane down the access shaft. When completed this cavern will have one of the largest spans constructed at 35 m, which required the roof to be supported by large steel anchors buried in concrete.

  6. End of construction of the CMS cavern

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    View of the CMS cavern with its impressive dimensions: 53 m long, 27 m wide and 24 m high. The construction of this underground complex has been a spectacular feat of engineering. This second of the new caverns for the LHC experiments is the result of six-and-a-half years of work, and its completion marks the end of the large-scale engineering work for the LHC.

  7. Civil Engineering in the ATLAS cavern

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    Ghostly figures can be seen wandering the cavern that will eventually house the ATLAS experiment, part of the LHC at CERN. Quite fitting since the detector will hunt the illusive 'ghostly' particles, such as the Higgs boson and dark matter. These engineers are excavating the huge cavern that has to be anchored from above as the detector will fill so much space that there is no room for support pillars.

  8. Extraosseous, Epidural Cavernous Hemangioma with Back Pain

    Science.gov (United States)

    Ozkal, Birol; Yaldiz, Can; Yaman, Onur; Ozdemır, Nail; Dalbayrak, Sedat

    2015-01-01

    Summary Background Cavernous malformations are characterized by enlarged vascular structures located in benign neural tissues within the cerebellum and spinal cord of the central nervous system. Cavernous hemangiomas (CHs) account for 5% to 12% of all spinal vascular malformations. Case Report We removed a hemorrhagic thoracic mass in a 40-year-old male patient who presented with progressive neurological deficits. Conclusions We found it appropriate to present this case due to its rarity. PMID:25960818

  9. Dorsal spinal epidural cavernous hemangioma

    Directory of Open Access Journals (Sweden)

    Darshana Sanghvi

    2010-01-01

    Full Text Available A 61-year-old female patient presented with diffuse pain in the dorsal region of the back of 3 months duration. The magnetic resonance imaging showed an extramedullary, extradural space occupative lesion on the right side of the spinal canal from D5 to D7 vertebral levels. The mass was well marginated and there was no bone involvement. Compression of the adjacent thecal sac was observed, with displacement to the left side. Radiological differential diagnosis included nerve sheath tumor and meningioma. The patient underwent D6 hemilaminectomy under general anesthesia. Intraoperatively, the tumor was purely extradural in location with mild extension into the right foramina. No attachment to the nerves or dura was found. Total excision of the extradural compressing mass was possible as there were preserved planes all around. Histopathology revealed cavernous hemangioma. As illustrated in our case, purely epidural hemangiomas, although uncommon, ought to be considered in the differential diagnosis of spinal epidural soft tissue masses. Findings that may help to differentiate this lesion from the ubiquitous disk prolapse, more common meningiomas and nerve sheath tumors are its ovoid shape, uniform T2 hyperintense signal and lack of anatomic connection with the neighboring intervertebral disk or the exiting nerve root. Entirely extradural lesions with no bone involvement are rare and represent about 12% of all intraspinal hemangiomas.

  10. A lymph nodal capillary-cavernous hemangioma.

    Science.gov (United States)

    Dellachà, A; Fulcheri, E; Campisi, C

    1999-09-01

    A capillary-cavernous hemangioma in an obturator lymph node was found incidentally in a 64 year-old woman who had undergone unilateral salpingo-oophorectomy and lymphadenectomy for an ovarian neoplasm. Vascular tumors of lymph nodes are briefly reviewed including eight previously described nodal capillary-cavernous hemangiomas. The association with other splanchnic hemangiomas is pointed out and the likelihood that the lesion is a hamartoma rather than a true neoplasm is addressed. Despite its rarity, this entity needs to be recognized by lymphologists who image lymph nodes by lymphangiography as well as by lymph nodal pathologists. PMID:10494525

  11. Cavernous haemangioma mimicking as clitoral hypertrophy

    Directory of Open Access Journals (Sweden)

    Sajid Nayyar

    2014-01-01

    Full Text Available Haemangioma is the most common benign neoplasm of infantile age. It is most commonly located in head and neck region, trunk and extremities but very rarely it can be located at clitoris. However, it is very important to differentiate clitoral haemangioma from enlargement of the clitoris secondary to androgen excess. Only four cases of clitoromegaly caused by cavernous haemangioma have been reported in the literature so far. Herein, we report our experience with a 10-year-old girl who presented with clitoromegaly and normal hormonal assay that turned out to be clitoral cavernous haemangioma after histopathological examination of the clitoral mass.

  12. Numerical Simulation of Gas Storage Caverns in Qom Region

    CERN Document Server

    Sharifzadeh, Mostafa

    2009-01-01

    The rock mechanical design of gas storage cavern in salt requires the analysis of the stability and the usability of the cavern over the planned operating time period. The design includes the build up of a rock mass model and a numerical model taking into account the geological situation, load condition, geometrical condition, and material parameters. In this paper multiple caverns in salt formation with geological and geomechanical situation in Qom (central part of Iran) was investigated a using creep model. Minimum safe center to center distances (CTCD) of multiple horizontal caverns also were studied. CTCD of caverns interact at less than two times of cavern diameter. With increasing the CTCD to 2.5 times cavern diameters, diminish most interaction.

  13. Imaging diagnosis of dural and direct cavernous carotid fistulae

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Daniela dos; Monsignore, Lucas Moretti; Nakiri, Guilherme Seizem; Cruz, Antonio Augusto Velasco e; Colli, Benedicto Oscar; Abud, Daniel Giansante, E-mail: danisantos2404@gmail.com [Universidade de Sao Paulo (HCFMRP/USP), Ribeirao Preto, SP (Brazil). Faculdade de Medicina. Hospital das Clinicas

    2014-07-15

    Arteriovenous fistulae of the cavernous sinus are rare and difficult to diagnose. They are classified into dural cavernous sinus fistulae or direct carotid-cavernous fistulae. Despite the similarity of symptoms between both types, a precise diagnosis is essential since the treatment is specific for each type of fistula. Imaging findings are remarkably similar in both dural cavernous sinus fistulae and carotid-cavernous fistulae, but it is possible to differentiate one type from the other. Amongst the available imaging methods (Doppler ultrasonography, computed tomography, magnetic resonance imaging and digital subtraction angiography), angiography is considered the gold standard for the diagnosis and classification of cavernous sinus arteriovenous fistulae. The present essay is aimed at didactically presenting the classification and imaging findings of cavernous sinus arteriovenous fistulae. (author)

  14. Tensile effective stresses in hydrocarbon storage caverns

    CERN Document Server

    Djizanne, Hippolyte; Brouard, Benoît

    2013-01-01

    The "no-tensile effective stress" criterion is discussed. It is proven that effective tensile stresses can be generated at a cavern wall after a rapid increase or decrease in pressure. The Etzel K-102 test, performed in Germany more than 20 years ago, is revisited using the notion of effective tensile stresses.

  15. Tensile effective stresses in hydrocarbon storage caverns

    OpenAIRE

    Djizanne, Hippolyte; Berest, Pierre; Brouard, Benoît

    2013-01-01

    International audience The "no-tensile effective stress" criterion is discussed. It is proven that effective tensile stresses can be generated at a cavern wall after a rapid increase or decrease in pressure. The Etzel K-102 test, performed in Germany more than 20 years ago, is revisited using the notion of effective tensile stresses.

  16. Entrevistando a un cavernísofo

    Directory of Open Access Journals (Sweden)

    Antonio Negrete

    2015-08-01

    Full Text Available Interview with Juan. A. Negrete, annual prize 2014 to the promotion of the philosophy and the culture in Málaga. The award is extended to the network of blogs: Cavernisofía, Cavernética and Cavernisofíasegundaplanta.

  17. Special people visit the ATLAS cavern

    CERN Multimedia

    Muriel

    ATLAS has been host to many important visitors lately. Here are a selected few: Professor Stephen Hawking visits the ATLAS cavern On Tuesday 26 September 2006 the ATLAS Collaboration was honoured by a very special visit to the detector in the underground cavern. We were pleased to guide Professor Stephen Hawking, the famous cosmologist holding the post of Lucasian Professor of Mathematics at Cambridge University (position held by Isaac Newton in the 17th century), on a tour of the ATLAS pit and the LHC tunnel. The visit was accompanied by a few colleagues from the CERN Theory group, and was only possible thanks to the professional assistance of Olga Beltramello and Bernard Lebegue, who had also taken care of all the necessary preparatory work in the cavern. Professor Hawking was very keen to check for himself the status of the detector installation, and he admired, in particular, the spectacular TGC big wheel on side C. (left) Stephen Hawking in the ATLAS cavern side-C (right) and in the LHC tunnel...

  18. The ATLAS cavern in the spotlight

    CERN Multimedia

    On Wednesday, 4th June, the President of the Swiss Confederation, Pascal Couchepin, inaugurated the world's largest experimental cavern, which is to house the ATLAS detector in 2007, and announced Switzerland's gift to CERN of the "Palais de l'Equilibre".

  19. Cavernous Hemangioma of the Bony Orbit

    Institute of Scientific and Technical Information of China (English)

    Jianhua Yan; Yu Cai; Zhongyao Wu; Ji Han; Youjian Pang

    2005-01-01

    Purpose: To study the clinical features, diagnosis and management of intraosseous cavernous hemangioma of the orbit.Methods: Five cases of intraosseous cavernous hemangioma seen in our hospital from Jan 1, 1986 to Dec 31, 2000 were reviewed.Results: Among all five cases, two were male and three were female. The mean age was 47.6 years old, ranging from 39.0 to 55.0 years. The left orbit was affected in 4 cases and the right one in 1 case. The bony involvement occurred in frontal bone (two cases),zygomatic bone (two cases) and sphenoid bone (one case). A painless, slowly enlarging hard bony mass fixed to the bone with no pulsations was the main clinical sign. The x-ray and CT appearance of intraosseous cavernous hemangioma of the orbit were characteristic and usually diagnostic. The differential diagnosis of it included fibrous dysplasia,eosinophilic granuloma, multiple myeloma and metastatic carcinoma. Treatment is local removal of the bone containing the tumor.Conclusions: Intraosseous cavernous hemangioma is a rare tumor of the orbit and usually has good surgical result.

  20. Percutaneous transvenous packing of cavernous sinus with Onyx for cavernous dural arteriovenous fistula

    Energy Technology Data Exchange (ETDEWEB)

    Lv Xianli [Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Chongwen, Beijing 100050 (China); Jiang Chuhan [Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Chongwen, Beijing 100050 (China)], E-mail: lvxianli000@163.com; Li Youxiang; Wu Zhongxue [Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, 6 Tiantan Xili, Chongwen, Beijing 100050 (China)

    2009-08-15

    Objective: The aim of this study is to describe the technique and results of the transvenous approach for occlusion of cavernous dural arteriovenous fistulas (DAVFs) with Onyx. Methods: Eleven patients presenting with clinically symptomatic DAVFs, were treated between August 2005 and February 2007 at Beijing Tiantan Hospital. We were able to navigate small hydrophilic catheters and microguidwires through the facial vein or inferior petrosal sinus (IPS) into the ipsilateral cavernous sinus. After reaching the fistula site the cavernous sinus was packed with Onyx or combining with detachable platinum coils. Results: We were able to reach the fistula site and to achieve a good packing of Onyx or combining with coils within the arteriovenous shunting zone in 10 patients. The final angiogram showed complete occlusion of the arteriovenous fistula. Two (18.2%) patients developed a bradycardia during DMSO injection. No complications related to the approach were observed. Conclusions: Transvenous occlusion of cavernous DAVFs is a feasible approach, even via facial vein or via IPS. Onyx may be another option for cavernous packing other than detachable platinum coils.

  1. Percutaneous transvenous packing of cavernous sinus with Onyx for cavernous dural arteriovenous fistula

    International Nuclear Information System (INIS)

    Objective: The aim of this study is to describe the technique and results of the transvenous approach for occlusion of cavernous dural arteriovenous fistulas (DAVFs) with Onyx. Methods: Eleven patients presenting with clinically symptomatic DAVFs, were treated between August 2005 and February 2007 at Beijing Tiantan Hospital. We were able to navigate small hydrophilic catheters and microguidwires through the facial vein or inferior petrosal sinus (IPS) into the ipsilateral cavernous sinus. After reaching the fistula site the cavernous sinus was packed with Onyx or combining with detachable platinum coils. Results: We were able to reach the fistula site and to achieve a good packing of Onyx or combining with coils within the arteriovenous shunting zone in 10 patients. The final angiogram showed complete occlusion of the arteriovenous fistula. Two (18.2%) patients developed a bradycardia during DMSO injection. No complications related to the approach were observed. Conclusions: Transvenous occlusion of cavernous DAVFs is a feasible approach, even via facial vein or via IPS. Onyx may be another option for cavernous packing other than detachable platinum coils.

  2. Numerical Simulations of Leakage from Underground LPG Storage Caverns

    OpenAIRE

    Yamamoto, Hajime; Pruess, Karsten

    2004-01-01

    To secure a stable supply of petroleum gas, underground storage caverns for liquified petroleum gas (LPG) are commonly used in many countries worldwide. Storing LPG in underground caverns requires that the surrounding rock mass remain saturated with groundwater and that the water pressure be higher than the liquid pressure inside the cavern. In previous studies, gas containment criteria for underground gas storage based on hydraulic gradient and pressure have been discussed, but these s...

  3. Neuraxis Cavernous Malformations: a Four Cases Report

    Directory of Open Access Journals (Sweden)

    Yandy Prieto Leyras

    2013-04-01

    Full Text Available Cavernous malformations are benign vascular tumors, with a raspberry-like morphology, commonly described as part of the group of the so called cryptic vascular malformations, which are rare neurological presentations. They are considered to be a controversial chapter in neuroscience due to the clinical-topographic variability of their presentation. Their management remains controversial. We present the cases of four patients with neuraxis cavernomas who are characterization from clinical and imaging standpoint, up to their final outcome. Early detection, understanding, and better management of the neuraxis cavernous malformations are the result of contemporary technological advances. The historical review on the subject shows the difference between the few cases that could be clinically diagnosed through conventional radiology and the largest number of lesions detected at autopsy or during surgery.

  4. Cavernous sinus extension of pituitary tumors

    International Nuclear Information System (INIS)

    This paper investigates the capability of ultrafast dynamic MR imaging to delineate cavernous sinus extension of pituitary region tumors. The dynamic imaging technique captures a temporal phase when Gd-DTPA-laden blood is in the vascular spaces, but the tumors have not yet enhanced and they appear as filling defects. This phase lasts less than 10 seconds. This information was helpful in the interpretation of seven equivocal cases (five positive, two negative), four of which were confirmed surgically. Dynamic imaging did not add to the determination of the pre- and postcontrast T1SE images in the remaining 15 patients. Dynamic imaging can be useful for delineating cavernous sinus extension of pituitary and perisellar tumors in cases in which the pre- and postgadolinium T1SE images are equivocal

  5. Neuraxis Cavernous Malformations: a Four Cases Report

    OpenAIRE

    Yandy Prieto Leyras; José Ramón Tejera del Valle; Mary Juliette Bonilla López; Néstor Pulido Ríos

    2013-01-01

    Cavernous malformations are benign vascular tumors, with a raspberry-like morphology, commonly described as part of the group of the so called cryptic vascular malformations, which are rare neurological presentations. They are considered to be a controversial chapter in neuroscience due to the clinical-topographic variability of their presentation. Their management remains controversial. We present the cases of four patients with neuraxis cavernomas who are characterization from clinical and ...

  6. Inauguration of the ATLAS cavern, June 2003.

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Before the inauguration, Pascal Couchepin visited the ATLAS cavern. From left to right: Peter Jenni, ATLAS spokesman; Maurice Bourquin, President of the CERN Council; Carlo Lamprecht, State councillor, Canton of Geneva; Pascal Couchepin, President of the Swiss Confederation; Luciano Maiani, CERN Director-General; Marzio Nessi, ATLAS technical coordinator; Arturo Henniger, ZSCHOKKE-LOCHER AG Director; Benno Baettig, personal advisor of President Couchepin; Jean-Luc Baldy, head of CERN Civil Engineering Group.

  7. Necrotizing Fasciitis of the Nose Complicated with Cavernous Sinus Thrombosis

    Directory of Open Access Journals (Sweden)

    D. Swaminath

    2014-01-01

    Full Text Available Necrotizing fasciitis is a rapidly progressive life threatening bacterial infection of the skin, the subcutaneous tissue, and the fascia. We present a case of necrotizing fasciitis involving the nose complicated by cavernous sinus thrombosis. Few cases of septic cavernous sinus thrombosis have been reported to be caused by cellulitis of the face but necrotizing fasciitis of the nose is rare. It is very important to recognize the early signs of cavernous thrombosis. Treatment for septic cavernous sinus thrombosis is controversial but early use of empirical antibiotics is imperative.

  8. Allowable pillar to diameter ratio for strategic petroleum reserve caverns.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L.; Park, Byoung Yoon

    2011-05-01

    This report compiles 3-D finite element analyses performed to evaluate the stability of Strategic Petroleum Reserve (SPR) caverns over multiple leach cycles. When oil is withdrawn from a cavern in salt using freshwater, the cavern enlarges. As a result, the pillar separating caverns in the SPR fields is reduced over time due to usage of the reserve. The enlarged cavern diameters and smaller pillars reduce underground stability. Advances in geomechanics modeling enable the allowable pillar to diameter ratio (P/D) to be defined. Prior to such modeling capabilities, the allowable P/D was established as 1.78 based on some very limited experience in other cavern fields. While appropriate for 1980, the ratio conservatively limits the allowable number of oil drawdowns and hence limits the overall utility and life of the SPR cavern field. Analyses from all four cavern fields are evaluated along with operating experience gained over the past 30 years to define a new P/D for the reserve. A new ratio of 1.0 is recommended. This ratio is applicable only to existing SPR caverns.

  9. Magnetic resonance imaging of the cavernous sinus

    Energy Technology Data Exchange (ETDEWEB)

    Komiyama, Masaki (Baba Memorial Hospital, Osaka (Japan))

    1990-08-01

    The magnetic resonance (MR) appearance of the cavernous sinus (CS) was studied in 10 normal and 23 abnormal CSs (11 vascular and 12 neoplastic lesions) using T{sub 1}-wighted spin echo images with and without Gd-DTPA. In normal CSs, the intracavernous carotid artery (ICA) was disclosed as an area of signal void that was not enhanced with Gd-DTPA. Most venous flow showed low intensity and was markedly enhanced with Gd-DTPA. Venous flow, however, was heterogeneous, which suggested the distribution of flow velocities. In the carotid-cavernous sinus fistulas (CCFs), the ICA and shunted flow were disclosed as areas of signal void and their relationship was clearly shown. Normal venous flow appeared as a low intensity area even with CCFs. In the cavernous aneurysms, thrombosis and patent arterial flow were shown, but in one case it was impossible to differentiate patent arterial flow from calcification. In neoplastic lesions, CS invasion was suspected by encasement or marked dislocation of the ICA, disappearance of venous flow, and extension of extrasellar tumors to the medial wall and extension of sellar tumors to the lateral wall. MR was found to be a promising diagnostic modality for the evaluation of the CS. (author).

  10. Magnetic resonance imaging of the cavernous sinus

    International Nuclear Information System (INIS)

    The magnetic resonance (MR) appearance of the cavernous sinus (CS) was studied in 10 normal and 23 abnormal CSs (11 vascular and 12 neoplastic lesions) using T1-wighted spin echo images with and without Gd-DTPA. In normal CSs, the intracavernous carotid artery (ICA) was disclosed as an area of signal void that was not enhanced with Gd-DTPA. Most venous flow showed low intensity and was markedly enhanced with Gd-DTPA. Venous flow, however, was heterogeneous, which suggested the distribution of flow velocities. In the carotid-cavernous sinus fistulas (CCFs), the ICA and shunted flow were disclosed as areas of signal void and their relationship was clearly shown. Normal venous flow appeared as a low intensity area even with CCFs. In the cavernous aneurysms, thrombosis and patent arterial flow were shown, but in one case it was impossible to differentiate patent arterial flow from calcification. In neoplastic lesions, CS invasion was suspected by encasement or marked dislocation of the ICA, disappearance of venous flow, and extension of extrasellar tumors to the medial wall and extension of sellar tumors to the lateral wall. MR was found to be a promising diagnostic modality for the evaluation of the CS. (author)

  11. Development of Indirect Cavernous Dural Arteriovenous Fistula after Trapping for Direct Carotid Cavernous Fistula: A Case Report

    OpenAIRE

    YOSHINO, H.; Ishihara, H.; Oka, F.; S. Kato; M. Suzuki

    2011-01-01

    A 60-year-old man with direct carotid cavernous fistula (CCF) due to a motor vehicle accident underwent internal carotid artery trapping following high-flow external carotid to internal carotid artery bypass (EC-IC bypass). Follow-up angiography revealed ipsilateral complex indirect cavernous arteriovenous fistula. Although the traumatic indirect CCF angioarchitecture differs from cavernous-sinus dural arteriovenous fistula (CS-DAVF), the present indirect fistula was similar to the latter. Co...

  12. Calcified cavernous hemangioma of the ovary: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yeon Hee [Dankook Univ. College of Medicine, Seoul (Korea, Republic of)

    2000-12-01

    Ovarian hemangiomas are very uncommon and most are of the cavernous type. A few reports have described the radiologic findings of this neoplasm, but as far as the author is aware, the literature contains no description of calcified cavernous hemangioma. A case in which this condition involved the ovary is now reported.

  13. Calcified cavernous hemangioma of the ovary: a case report

    International Nuclear Information System (INIS)

    Ovarian hemangiomas are very uncommon and most are of the cavernous type. A few reports have described the radiologic findings of this neoplasm, but as far as the author is aware, the literature contains no description of calcified cavernous hemangioma. A case in which this condition involved the ovary is now reported

  14. Design of cavern blasting based on controllable parameters

    Institute of Scientific and Technical Information of China (English)

    WANG Shu-li; WANG Shu-ren; ZHU Jian-ming

    2008-01-01

    After a thorough review of some controllable parameters, which included field investigations, cavern dimensions, explosive, rock strength etc., cut, contour, lifters and stoping holes were introduced for blasting cavern of nucleus submarine. These design were conducted using a U. Langefors and B. Kihlstrom theory.

  15. 36 CFR 7.47 - Carlsbad Caverns National Park.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Carlsbad Caverns National Park. 7.47 Section 7.47 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.47 Carlsbad Caverns National Park....

  16. Recovery of opthalmoplegia associated with cavernous sinus dural arteriovenous fistulas after transvenous cavernous sinus packing

    Energy Technology Data Exchange (ETDEWEB)

    Lv Xianli; Jiang Chuhan; Li Youxiang; Yang Xinjian [Beijing Neurosurgical institute, Beijing Tiantan Hospital, Capital Medical University, 6, Tiantan Xili, Chongwen, Beijing (China); Wu Zhongxue, E-mail: ttyyzjb@sina.co [Beijing Neurosurgical institute, Beijing Tiantan Hospital, Capital Medical University, 6, Tiantan Xili, Chongwen, Beijing (China)

    2010-08-15

    Background: We report the recovery of ophthalmoplegia in 11 patients with cavernous sinus dural arteriovenous fistula (CSDAVF) after sinus packing at follow-up. Methods: Of 18 patients with CSDAVF treated with transvenous cavernous sinus packing between August 2002 and December 2007 at Beijing Tiantan Hospital, there were 9 patients with initial CNIII or CNVI dysfunction and 2 patients with CNVI dysfunction immediately after cavernous sinus packing selected and reevaluated. Results: Of 11 patients with CNIII or CNVI palsy, recovery was complete in 10. In 1 patient, complete CNVI palsy was unchanged because the CSDAVF was not cured. There were 6 men and 5 women with a mean age of 52.9 years. In 5 patients, CNVI palsy was associated with chemosis, proptosis and pulsatile tinnitus. Timing of treatment after onset of symptoms was from 4 to 35 days in 9 patients. All CSDAVFs were Barrow type D. Mean follow-up after treatment was 17.7 months (range, 2-54 months). Conclusion: CSDAVF-induced CNIII or CNVI palsies can be cured after cavernous sinus packing transvenously in most patients.

  17. CAVERNOUS HEMANGIOMA OF THE INTERNAL AUDITORY CANAL

    Directory of Open Access Journals (Sweden)

    Mohammad Hossein Hekmatara

    1993-06-01

    Full Text Available Cavernous hemangioma is a rare benign tumor of the internal auditory canal (IAC of which fourteen cases have been reported so far."nTinnitus and progressive sensorineural hearing loss (SNHL are the chief complaints of the patients. Audiological and radiological planes, CTScan, and magnetic resonance image (MRI studies are helpful in diagnosis. The only choice of treatment is surgery with elective transmastoid trans¬labyrinthine approach. And if tumor is very large, the method of choice will be retrosigmoid approach.

  18. Meningioma and cavernous angioma following childhood radiotherapy

    Directory of Open Access Journals (Sweden)

    Baheti Akshay

    2010-01-01

    Full Text Available Prophylactic cranial irradiation has been a part of multimodality management of acute lymphoblastic leukemia (ALL. With optimum treatment and the resultant long-term cure rates, long-term side effects of radiation including radiation-induced neoplasms have been increasingly unearthed. We report a rare case of development of both a meningioma and a cavernous angioma following prophylactic cranial irradiation as a part of treatment of ALL. Regular follow-up and high index of suspicion for late radiation sequelae after treatment are therefore justifiable in leukemia survivors with history of prophylactic cranial irradiation.

  19. Multiple CNS cavernous haemangiomas presenting with spinal cord haematoma secondary to an intra-medullary cavernous haemangioma: A case report

    International Nuclear Information System (INIS)

    Background: Spinal vascular malformations are rare. Intra-medullary cavernous haemangiomas are very rare and only few cases have been described. Occasionally they may cause pain, myelopathy with sensory or motor deficit due to mass effect or hemorrhage. Case Report: We report a patient who presented to the emergency department with acute retention of urine and lower limb weakness. He was diagnosed as a spinal intramedullary haematoma secondary to a cavernous haemangioma. In addition, multiple intracranial cavernous haemangiomas were found. Conclusions: We are of the opinion that our case of spinal intramedullary cavernous haemangioma with multiple intracranial involvements deserves attention due to its rarity and it is also an important reminder to examine the whole neuroaxis in patients with spinal intramedullary cavernous haemangiomas, regardless they are symptomatic or asymptomatic

  20. Vascular permeability in cerebral cavernous malformations

    DEFF Research Database (Denmark)

    Mikati, Abdul G; Khanna, Omaditya; Zhang, Lingjiao;

    2015-01-01

    Patients with the familial form of cerebral cavernous malformations (CCMs) are haploinsufficient for the CCM1, CCM2, or CCM3 gene. Loss of corresponding CCM proteins increases RhoA kinase-mediated endothelial permeability in vitro, and in mouse brains in vivo. A prospective case-controlled observ......Patients with the familial form of cerebral cavernous malformations (CCMs) are haploinsufficient for the CCM1, CCM2, or CCM3 gene. Loss of corresponding CCM proteins increases RhoA kinase-mediated endothelial permeability in vitro, and in mouse brains in vivo. A prospective case......-controlled observational study investigated whether the brains of human subjects with familial CCM show vascular hyperpermeability by dynamic contrast-enhanced quantitative perfusion magnetic resonance imaging, in comparison with CCM cases without familial disease, and whether lesional or brain vascular permeability...... correlates with CCM disease activity. Permeability in white matter far (WMF) from lesions was significantly greater in familial than in sporadic cases, but was similar in CCM lesions. Permeability in WMF increased with age in sporadic patients, but not in familial cases. Patients with more aggressive...

  1. Beta adrenergic receptors in human cavernous tissue

    International Nuclear Information System (INIS)

    Beta adrenergic receptor binding was performed with 125I iodocyanopindolol on human cavernous tissue membrane fractions from normal tissue and transsexual procedures obtained postoperatively, as well as from postmortem sources. Isotherm binding studies on normal fresh tissues indicated that the receptor density was 9.1 fmoles/mg. with a KD of 23 pM. Tissue stored at room temperature for 4 to 6 hours, then at 4C in saline solution for 19 to 20 hours before freezing showed no significant changes in receptor density or affinity, and provided evidence for the stability of postmortem tissue obtained within the same time period. Beta receptor density of 2 cavernous preparations from transsexual procedures was not significantly different from normal control tissues, and showed that high concentrations of estrogen received by these patients had no effect on beta adrenergic receptor density. Displacement of 125iodocyanopindolol by 5 beta adrenergic agents demonstrated that 1-propranolol had the greatest affinity followed by ICI 118,551, zinterol, metoprolol and practolol. When the results of these displacement studies were subjected to Scatfit, non- linear regression line analysis, a single binding site was described. Based on the relative potency of the selective beta adrenergic agents it appears that these receptors were of the beta 2 subtype

  2. Beta adrenergic receptors in human cavernous tissue

    Energy Technology Data Exchange (ETDEWEB)

    Dhabuwala, C.B.; Ramakrishna, C.V.; Anderson, G.F.

    1985-04-01

    Beta adrenergic receptor binding was performed with /sup 125/I iodocyanopindolol on human cavernous tissue membrane fractions from normal tissue and transsexual procedures obtained postoperatively, as well as from postmortem sources. Isotherm binding studies on normal fresh tissues indicated that the receptor density was 9.1 fmoles/mg. with a KD of 23 pM. Tissue stored at room temperature for 4 to 6 hours, then at 4C in saline solution for 19 to 20 hours before freezing showed no significant changes in receptor density or affinity, and provided evidence for the stability of postmortem tissue obtained within the same time period. Beta receptor density of 2 cavernous preparations from transsexual procedures was not significantly different from normal control tissues, and showed that high concentrations of estrogen received by these patients had no effect on beta adrenergic receptor density. Displacement of /sup 125/iodocyanopindolol by 5 beta adrenergic agents demonstrated that 1-propranolol had the greatest affinity followed by ICI 118,551, zinterol, metoprolol and practolol. When the results of these displacement studies were subjected to Scatfit, non- linear regression line analysis, a single binding site was described. Based on the relative potency of the selective beta adrenergic agents it appears that these receptors were of the beta 2 subtype.

  3. Dural fistulas of the cavernous sinus

    Energy Technology Data Exchange (ETDEWEB)

    Guibert-Tranier, F.; Piton, J.; Caille, J.M.; Lemoine, J.J.

    1984-11-01

    Five cases of dural fistulas of the cavernous sinus are reported. The clinical aspect of this lesion is often misleading in the absence of subjective or objective bruits. The diagnosis is made at angiography which should systematically include the internal and external carotid arteries bilaterally. The goal of this study was to elucidate the great variability of the venous drainage and to correlate it with the clinical symptoms and course. The main problem is to know when and how these fistulas should be treated. Vascular ligatures should not be performed. Therapeutic angiography is the treatment of choice, but should be limited to the following indications: poorly tolerated bruits, severe ophthalmic damage (elevated ocular tension, diminished visual acuity, or oculomotor paralysis), angiographically demonstrated massive arteriovenous shunting, and a high degree of cortical venous reflux. Whatever the indication, the course after embolisation is rarely predictable and in particular the risk of extensive venous thrombosis or recurrence is great.

  4. Dural fistulas of the cavernous sinus

    International Nuclear Information System (INIS)

    Five cases of dural fistulas of the cavernous sinus are reported. The clinical aspect of this lesion is often misleading in the absence of subjective or objective bruits. The diagnosis is made at angiography which should systematically include the internal and external carotid arteries bilaterally. The goal of this study was to elucidate the great variability of the venous drainage and to correlate it with the clinical symptoms and course. The main problem is to know when and how these fistulas should be treated. Vascular ligatures should not be performed. Therapeutic angiography is the treatment of choice, but should be limited to the following indications: poorly tolerated bruits, severe ophthalmic damage (elevated ocular tension, diminished visual acuity, or oculomotor paralysis), angiographically demonstrated massive arteriovenous shunting, and a high degree of cortical venous reflux. Whatever the indication, the course after embolisation is rarely predictable and in particular the risk of extensive venous thrombosis or recurrence is great. (orig.)

  5. [Cavernous hemangioma confined to the tongue].

    Science.gov (United States)

    Galletti, C

    1988-12-01

    The authors relate on a case of an isolated cavernous haemangioma of the body of the tongue characterized by considerable size. Such neoplasms, usually described within the more extensive chapter of the more common angiomatous lesion of the oral cavity, are relatively rare. The authors describe a personal case discussing the diagnostic spects of such lesion and emphasizing the importance of the arteriography of the carotid artery and the of the selective arteriography of the lingual arteries, especially in considering surgery. Biopsies are not recommended. After discussing the histopathological and clinical aspects of such lesions the Authors emphasize the therapeutic ones. Even though radiotherapy, cryotherapy, laser therapy, medical treatment, injection of sclerosing substances and the selective embolization, of the lingual artery seem to have some efficacy, the authors conclude that surgery in the therapy of choice in the isolated vascular lesions of the body of the tongue. PMID:3274631

  6. THE DIAGNOSIS OF MAGNETIC RESONANCE IMAGING FOR SPINAL CAVERNOUS ANGIOMAS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Objective To assess the characteristics of magnetic resonance imaging (MRI) for spinal cavernous angiomas.Methods The examinations of plain scan and contrast enhanced scan of magnetic resonance (MR) were performed in three patients with spinal cavernous angiomas.Results The focus of two cases was located in thorax segment of the spinal cord and one in lower cervical segment.All focuses were single and the shape of spinal cord was normal or slightly thick. MRI characteristic of spinal cavernous angiomas was just like popcorn or mulberry with a jumbled gobbet signal. Low and short T2 signal appeared around the focus. In all cases, there were no obvious contrast enhanced signal in 2 cases and one case with moderate contrast enhanced signal. The diameter of hemorrhage was smaller than that of the spinal cord.Conclusion MRI has higher sensitivity and specificity in the diagnosis of spinal cavernous angioma.

  7. ATLAS - End-Cap calorimeter lowered in to the cavern

    CERN Multimedia

    IT-UDS Audiovisual Services

    2006-01-01

    The End-cap calorimeter was lowered into the ATLAS cavern at POINT1. This calorimeter will measure the energy of particles close to the beam axis when protons collide. Cooling is important for maximum detector efficiency.

  8. The comparison study of MR scanning sequence on cavernous sinus syndrome

    International Nuclear Information System (INIS)

    Objective: To compare the value of different MR sequence on evaluating cavernous sinus syndrome. Methods: Routine head MR scan sequence; thin slice scanning of cavernous sinus area with FSE T1WI, T2WI, STIR sequences, 3D-FIESTA sequence, enhanced FSE T1WI sequence were performed in 33 cases with cavernous sinus syndrome. And the display of cavernous sinus was analyzed. Results: Detection rate of cavernous sinus syndrome was 72.7% with routine head MR scan, 84.8% with cavernous sinus thin slice scanning, 87.8% with 3D-FIESTA sequence and 92.9% with enhanced T1WI scan. Conclusion: Routine MR head scan will miss diagnosis of cavernous sinus syndrome in some degree; cavernous sinus thin slice scanning and 3D-FIESTA sequence can detecte the lesions better and the best way in using enhanced T1WI scan to detect and characterize cavernous sinus syndrome. (authors)

  9. Configuration of Fibrous and Adipose Tissues in the Cavernous Sinus

    OpenAIRE

    Liang, Liang; Gao, Fei; Xu, Qunyuan; Zhang, Ming

    2014-01-01

    Objective Three-dimensional anatomical appreciation of the matrix of the cavernous sinus is one of the crucial necessities for a better understanding of tissue patterning and various disorders in the sinus. The purpose of this study was to reveal configuration of fibrous and adipose components in the cavernous sinus and their relationship with the cranial nerves and vessels in the sinus and meningeal sinus wall. Materials and Methods Nineteen cadavers (8 females and 11 males; age range, 54–89...

  10. Studies on the construction of underground rock cavern

    International Nuclear Information System (INIS)

    Underground rock cavern for pump storage power stations have reinforced concrete lining at the vault, generally. Stress of reinforcing bar in the lining was measured in many of these caverns. This report describes the mechanism of stress origination in the vault lining, which is found of investigation of the actual measurements and numerical analysis. Stress in the vault lining is caused by temperature change and deformation of cavern wall due to excavation, mainly. It needs special care to the tall or long cavern that compressive stress increases according to the reduction of the arch span on the process of cutting-down of bench. If rock mass around the cavern is igneous and jointy, compressive stress will be very large. To take the average of measured values, stress at the end part of arch is smaller than the crown part. These results obtained from actual servey will be useful to the design of the vault lining of large cavern for nuclear power station and others, from now on. (author)

  11. ADVANCED UNDERGROUND GAS STORAGE CONCEPTS REFRIGERATED-MINED CAVERN STORAGE

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    Limited demand and high cost has prevented the construction of hard rock caverns in this country for a number of years. The storage of natural gas in mined caverns may prove technically feasible if the geology of the targeted market area is suitable; and economically feasible if the cost and convenience of service is competitive with alternative available storage methods for peak supply requirements. It is believed that mined cavern storage can provide the advantages of high delivery rates and multiple fill-withdrawal cycles in areas where salt cavern storage is not possible. In this research project, PB-KBB merged advanced mining technologies and gas refrigeration techniques to develop conceptual designs and cost estimates to demonstrate the commercialization potential of the storage of refrigerated natural gas in hard rock caverns. Five regions of the U.S.A. were studied for underground storage development and PB-KBB reviewed the literature to determine if the geology of these regions was suitable for siting hard rock storage caverns. Area gas market conditions in these regions were also studied to determine the need for such storage. Based on an analysis of many factors, a possible site was determined to be in Howard and Montgomery Counties, Maryland. The area has compatible geology and a gas industry infrastructure for the nearby market populous of Baltimore and Washington D.C.. As Gas temperature is lowered, the compressibility of the gas reaches an optimum value. The compressibility of the gas, and the resultant gas density, is a function of temperature and pressure. This relationship can be used to commercial advantage by reducing the size of a storage cavern for a given working volume of natural gas. This study looks at this relationship and and the potential for commercialization of the process in a storage application. A conceptual process design, and cavern design were developed for various operating conditions. Potential site locations were considered

  12. Cerebral cavernous malformations. Serial magnetic resonance imaging findings in patients with and without gamma knife surgery

    International Nuclear Information System (INIS)

    To classify the cerebral cavernous malformations and to investigate the natural history of cavernous malformations according to the classification, 41 patients with 61 cavernous malformations (40 cavernous malformations from 22 patients treated with gamma knife surgery) were regularly followed up using MR imaging for a mean period of 25.5 months in treated cavernous malformations and 20.7 months in untreated cavernous malformations, respectively. Cavernous malformations were classified into four types. Follow-up MR images were analyzed to evaluate changes in size, signal intensity, rebleeding, and perilesional adverse reaction of irradiation. A total of 61 cavernous malformations including 17 in type I, 23 in type II, 10 in type III, and 11 in type IV showed usual degradation of blood product in 22 cavernous malformations, no change in shape and signal intensity in 31 cavernous malformations, and eight cavernous malformations with rebleedings in the serial MR images. In these eight cavernous malformations with rebleedings, six occurred in type II and two in type III, but none in type I or IV. Rebleedings were more frequent in type II than in other types. Adverse reaction of irradiation was observed in five of 22 patients treated with gamma knife surgery. Although most cerebral cavernous malformations showed evolution of hemorrhage or no change in size or shape on follow-up MR images, cerebral cavernous malformations represented as mixture of subacute and chronic hemorrhage with hemosiderin rim (type II) have a higher frequency to rebleed than other types of cerebral cavernous malformations. Cerebral cavernous malformations represented as hemosiderin deposition without central core (type IV) have a lower tendency to rebleed than other types and do not need any treatment. Most of the adverse reaction of irradiation after gamma knife surgery around cavernous malformations are transient findings and are considered to be perilesional edema. (K.H)

  13. Features of Bayou Choctaw SPR caverns and internal structure of the salt dome.

    Energy Technology Data Exchange (ETDEWEB)

    Munson, Darrell E.

    2007-07-01

    The intent of this study is to examine the internal structure of the Bayou Choctaw salt dome utilizing the information obtained from graphical representations of sonar survey data of the internal cavern surfaces. Many of the Bayou Choctaw caverns have been abandoned. Some existing caverns were purchased by the Strategic Petroleum Reserve (SPR) program and have rather convoluted histories and complex cavern geometries. In fact, these caverns are typically poorly documented and are not particularly constructive to this study. Only two Bayou Choctaw caverns, 101 and 102, which were constructed using well-controlled solutioning methods, are well documented. One of these was constructed by the SPR for their use while the other was constructed and traded for another existing cavern. Consequently, compared to the SPR caverns of the West Hackberry and Big Hill domes, it is more difficult to obtain a general impression of the stratigraphy of the dome. Indeed, caverns of Bayou Choctaw show features significantly different than those encountered in the other two SPR facilities. In the number of abandoned caverns, and some of those existing caverns purchased by the SPR, extremely irregular solutioning has occurred. The two SPR constructed caverns suggest that some sections of the caverns may have undergone very regular solutioning to form uniform cylindrical shapes. Although it is not usually productive to speculate, some suggestions that point to the behavior of the Bayou Choctaw dome are examined. Also the primary differences in the Bayou Choctaw dome and the other SPR domes are noted.

  14. Hemiparesis in carotid cavernous fistulas (CCFs):a case report and review of the literature

    Institute of Scientific and Technical Information of China (English)

    王慧晓; 白如林; 黄承光; 卢亦成; 张光霁

    2004-01-01

    @@ Carotid-cavernous fistulas (CCFs) are abnormal arteriovenous anastamoses between the carotid artery and the cavernous sinus. These fistulas may be classified by cause (spontaneous or traumatic), flow velocity (high or low ), or pathogenesis (direct or indirect).

  15. Review of spinal epidural cavernous hemangioma

    International Nuclear Information System (INIS)

    The characteristics of spinal epidural cavernous hemangioma without primary origin in the vertebral bone were evaluated in 54 patients including our new case. The 36 male and 18 female patients were aged 5 to 78 years (mean 47 years). Most lesions were in the thoracic spine (80%) and on the dorsal side of the spinal cord (93%). The clinical course was mostly slowly progressive, with myelopathy in 33% at onset and 83% at admission. The lesion appeared isointense to the spinal cord on T1-weighted imaging, and isointense or slightly hypointense to the cerebrospinal fluid on T2-weighted imaging. Lesion without hemorrhage showed prominent homogeneous enhancement after administration of gadolinium-diethylenetriaminepenta-acetic acid because of the sinusoidal channel structure. Heterogeneous enhancement was caused by hematoma and/or post-hemorrhagic degeneration. The differential diagnosis of this disease includes metastatic tumor, Ewing's sarcoma, chordoma, eosinophilic granuloma, sarcoidosis, lipoma, hypertrophy of the posterior longitudinal ligament or the ligamentum flavum, meningioma, and neurinoma. The relationships between clinical course and surgery or outcome suggest that early diagnosis and total removal of the lesion before massive lesional bleeding occurs are necessary for a good outcome. (author)

  16. Endovascular embolization for the treatment of carotid cavernous fistula: recent progresses in research

    International Nuclear Information System (INIS)

    Carotid cavernous fistula is the abnormal arteriovenous communications, which can be located within the internal carotid cavernous segment itself, or between the cavernous and the internal carotid branches or external carotid meningeal branches. With the development of interventional neuroradiology, endovascular embolization has become the choice of treatment for the carotid cavernous fistula, as the technique is less invasive, simple and reliable. This paper aims to review the recent progresses in this respect in order to further improve its clinical diagnosis and treatment. (authors)

  17. Underground hydrogen storage. Final report. [Salt caverns, excavated caverns, aquifers and depleted fields

    Energy Technology Data Exchange (ETDEWEB)

    Foh, S.; Novil, M.; Rockar, E.; Randolph, P.

    1979-12-01

    The technical and economic feasibility of storing hydrogen in underground storage reservoirs is evaluated. The past and present technology of storing gases, primarily natural gas is reviewed. Four types of reservoirs are examined: salt caverns, excavated caverns, aquifers, and depleted fields. A technical investigation of hydrogen properties reveals that only hydrogen embrittlement places a limit on the underground storage by hydrogen. This constraint will limit reservoir pressures to 1200 psi or less. A model was developed to determine economic feasibility. After making reasonable assumptions that a utility might make in determining whether to proceed with a new storage operation, the model was tested and verified on natural gas storage. A parameteric analysis was made on some of the input parameters of the model to determine the sensitivity of the cost of service to them. Once the model was verified it was used to compute the cost of service of storing hydrogen in the four reservoir types. The costs of service for hydrogen storage ranged from 26 to 150% of the cost of the gas stored. The study concludes that it is now both safe and economic to store hydrogen in underground reservoirs.

  18. Bedded salt in Ontario : geology, solution mining and cavern storage

    Energy Technology Data Exchange (ETDEWEB)

    Carter, T. [Ontario Ministry of Natural Resources, London, ON (Canada). Petroleum Resources Centre

    2009-07-01

    This presentation discussed bedded salt geology in Ontario in relation to cavern storage and solution mining. Ontario's salt basin forms part of the Michigan basin. The salt formed as reefs surrounding the shallow basin restricted the flow of water. Salt then formed as the water evaporated. The bedded salt occurs in several layers underlying up to 16,000 km{sup 2} in the province. Subsurface resources used in the area include salt cavern hydrocarbon storage; oil and gas reservoirs; and natural gas reservoir storage. The Salina Group stratigraphy is comprised of several separate salt beds with a maximum combined thickness of 90 m. The Salina salt beds exhibit evidence of dissolution after deposition. There are currently 20 active solution mining wells in operation in the Windsor and Goderich regions. There are currently 112 wells and 70 caverns used for cavern storage in Ontario that are used to store approximately 27 million bbl of liquefied petroleum gas (LPG) and oil. Non-salt layers in the salt beds can interfere with both solution mining and cavern storage operations. tabs., figs.

  19. Endoscopic transsphenoidal approach to pituitary adenomas invading the cavernous sinus

    Institute of Scientific and Technical Information of China (English)

    TAO Yu-xin; QU Qiu-yi; WANG Zhen-lin; ZHANG Qiu-hang

    2010-01-01

    Background Surgery of pituitary adenomas invading cavernous sinus has always been thought as a challenge due to the complex anatomical structures and high risk of complications. The purpose of this study was to evaluate endoscopic trarssphenoidal approach to pituitary adenomas invading cavernous sinus.Methods The clinical data of 22 patients who admitted to Xuanwu Hospital with pituitary adenomas invading cavernous sinus were analyzed retrospectively. All patients underwent endoscopic transsphenoidal surgery. To expose the surgical field sufficiently, the opening of sellar floor was exceeded the bone overlying the invaded cavernous sinus, and synthetic dura was used to repair and strengthen the sella floor for preventing the leak of cerebrospinal fluid.Results Among 22 patients, total resection was achieved in 14, subtotal resection in 5, and partial resection in 3; no patient underwent insufficient resection. Visual symptoms improved in 7 of 9 patients. In one patient diplopia disappeared.Headache was relieved to various extents in all patients. No serious complications were found. Patient's hospital stay ranged from 7 to 20 days.Conclusion These data suggest that the endoscopic transsphenoid approach is a safe, minimally invasive, and efficient surgical technique, which might be an important therapeutic strategy for the pituitary adenoms invading cavernous sinus.

  20. Cavernous angioma of the optic chiasm--case report.

    Science.gov (United States)

    Iwai, Y; Yamanaka, K; Nakajima, H; Miyaura, T

    1999-08-01

    A 31-year-old female presented with cavernous angioma originating from the optic chiasm manifesting as sudden onset of right retroorbital pain and right visual disturbance. She had a psychomotor seizure 10 years ago. Cavernous angioma at the right basal ganglia had been partially removed at that time. After the operation, the patient had left hemiparesis, but gradually improved. Neurological examination revealed decreased right visual acuity, left homonymous hemianopsia, and left hemiparesis. Magnetic resonance imaging revealed a mixed signal intensity mass at the right optic nerve to the optic chiasm with a low signal intensity rim on T2-weighted imaging, situated at the right basal ganglia where the cavernous angioma had been partially resected. Right frontotemporal craniotomy was performed by the pterional approach. A subpial hematoma was situated at the right optic nerve to the optic chiasm. The hematoma with an angiomatous component was completely resected from the surrounding structure. Histological examination of the specimens confirmed cavernous angioma. Postoperatively, her right visual acuity was slightly improved, but the visual field defect was unchanged. We emphasize the importance of correct diagnosis by magnetic resonance imaging and subsequent resection for preserving and improving the visual function of patients with cavernous angiomas of the optic chiasm. PMID:10487042

  1. [Trigeminal-cavernous fistula. Report of a case and review of the literature].

    Science.gov (United States)

    Santos Franco, Jorge; Sánchez Olivera, Carlos; Saavedra Andrade, Rafael; Sandoval Balanzario, Miguel Antonio

    2013-01-01

    Persistent primitive trigeminal artery is a rare anatomical variant resulting from the absence of obliteration of the embryonic trigeminal artery. The shunt between the persistent primitive trigeminal artery and the cavernous sinus is called trigeminal-cavernous fistula. We report the case of a woman with a trigeminal-cavernous fistula secondary to head trauma who was treated by transarterial embolization. PMID:24108341

  2. Case history: blowout at an LPG storage cavern in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Hamberger, Ulrika

    1991-01-01

    A ''blowout'' occurred when an additional well was drilled to secure sufficient water pressure at an underground LPG storage cavern in September 1989. The leak was stopped after 12 hours. By grouting through the drill rod, it was possible to fill up the cavity around the drill bit. It was then possible to grout the hole up to ground level. The 48,000 m{sup 3}-capacity underground storage, which is located in Karlshamn on the south coast of Sweden, has been in operation since April 1990. Storage is accomplished under hydrostatic water conditions. The storage cavern is placed at such a depth so as to guarantee a sufficient groundwater pressure above the whole storage. A ''curtain'' of drill holes, which efficiently spread the groundwater, is placed above the cavern. The groundwater was carefully observed in wells during the excavation period and these observations continue. (author).

  3. Two new caverns for LHC experiments ATLAS and CMS

    CERN Document Server

    Rammer, H

    1998-01-01

    The LHC will utilize much of the existing infrastructure already constructed for the LEP. However, to house the new ATLAS and CMS detectors, two huge cavern complexes are required at Point 1 and Point 5 on the LEP. The civil engineering design criteria for the two caverns are presented. Attention is directed to the decisive constraints for the design, such as adverse geological ground conditions, the three-dimensional complexity of the shafts, caverns and tunnels, and the existing LEP structures in the vicinity of the new works which remain operational for the first two years of the project. the paper will demonstrate the different basic requirements of the new underground structures at Point 1 and Point 5. The comparison of the two projects from a civil engineering point of view will aim at explaining why different technical solutions have been adopted for the design and construction of these works.

  4. Giant hepatic cavernous hemangioma. Findings on computed helical tomography

    International Nuclear Information System (INIS)

    Objective: To describe computed helical tomography characteristics of the giant hepatic cavernous hemangioma. Method: During five years, we evaluated 21 patients with 21 giant hepatic cavernous hemangiomas with computed helical and multislice tomography. We included 18 women (86%) and 3 men (14%) with a mean age of 45 years. Results: The mean size of hemangiomas was 10.4 cm. Non enhanced computed tomography Showed 21 hemangiomas with lower density than adjacent hepatic parenchyma , all hemangiomas showed a central cleft area with low density. None hemangioma showed calcifications neither internal septa. In enhanced helical tomography all lesions demonstrated a globular, peripheral enhancing pattern with centripetal filling that begin in the arterial phase and continued in portal and delayed phases. None of the lesions showed complete filling. Conclusion: giant hepatic cavernous hemangiomas showed low attenuation in non enhanced computed tomography. central cleft area was very frequently seen. The enhancement pattern is characteristic, starting at the periphery with centripetal filling but it was never complete.

  5. Tolerance of cranial nerves of the cavernous sinus to radiosurgery

    International Nuclear Information System (INIS)

    Stereotactic radiosurgery is becoming a more accepted treatment option for benign, deep seated intracranial lesions. However, little is known about the effects of large single fractions of radiation on cranial nerves. This study was undertaken to assess the effect of radiosurgery on the cranial nerves of the cavernous sinus. The authors examined the tolerance of cranial nerves (II-VI) following radiosurgery for 62 patients (42/62 with meningiomas) treated for lesions within or near the cavernous sinus. Twenty-nine patients were treated with a modified 6 MV linear accelerator (Joint Center for Radiation Therapy) and 33 were treated with the Gamma Knife (University of Pittsburgh). Three-dimensional treatment plans were retrospectively reviewed and maximum doses were calculated for the cavernous sinus and the optic nerve and chiasm. Median follow-up was 19 months (range 3-49). New cranial neuropathies developed in 12 patients from 3-41 months following radiosurgery. Four of these complications involved injury to the optic system and 8 (3/8 transient) were the result of injury to the sensory or motor nerves of the cavernous sinus. There was no clear relationship between the maximum dose to the cavernous sinus and the development of complications for cranial nerves III-VI over the dose range used (1000-4000 cGy). For the optic apparatus, there was a significantly increased incidence of complications with dose. Four of 17 patients (24%) receiving greater than 800 cGy to any part of the optic apparatus developed visual complications compared with 0/35 who received less than 800 cGy (p = 0.009). Radiosurgery using tumor-controlling doses of up to 4000 cGy appears to be a relatively safe technique in treating lesions within or near the sensory and motor nerves (III-VI) of the cavernous sinus. The dose to the optic apparatus should be limited to under 800 cGy. 21 refs., 4 tabs

  6. A new shape design method of salt cavern used as underground gas storage

    International Nuclear Information System (INIS)

    Graphical abstract: Safety factor contours of four salt cavern gas storages after running 10 years. Highlights: ► We propose a new model to design the shape of salt cavern gas storage. ► The concepts of slope instability and pressure arch are introduced into the shape design. ► The max. gas pressure determines the shapes and dimensions of cavern lower structure. ► The min. gas pressure decides the shapes and dimensions of cavern upper structure. - Abstract: A new model used to design the shape and dimension of salt cavern gas storage is proposed in the paper. In the new model, the cavern is divided into two parts, namely the lower and upper structures, to design. The concepts of slope instability and pressure arch are introduced into the shape design of the lower and upper structures respectively. Calculating models are established according to the concepts. Field salt cavern gas storage in China is simulated as examples, and its shape and dimension are proposed. The effects of gas pressure, friction angle and cohesion of rock salt on the cavern stability are discussed. Moreover, the volume convergence, displacement, plastic volume rate, safety factor, and effective strain are compared with that of three other existing shapes salt caverns to validate the performance of newly proposed cavern. The results show that the max. gas pressure determines the shape and dimension of cavern lower structure, while the min. gas pressure decides that of cavern upper structure. With the increase of friction angle and cohesion of rock salt, the stability of salt cavern is increased. The newly proposed salt cavern gas storage has more notable advantages than the existing shapes of salt cavern in volume convergence, displacement, plastic volume rate, safety factor, and effective strain under the same conditions

  7. [Ovarian torsion revealing an ovarian cavernous hemangioma in a child].

    Science.gov (United States)

    M'pemba Loufoua-Lemay, A-B; Peko, J-F; Mbongo, J-A; Mokoko, J-C; Nzingoula, S

    2003-11-01

    The authors report one case of cavernous hemangioma of the left ovary, which was revealed by ovarian torsion. Such benign tumors of the blood vessels are rare in ovaries during childhood. This hemangioma was observed in a 13-year-old patient, who presented with abdominal and pelvic pain and vomiting. The pelvic mass was noted and sonography revealed a cystic tumor. An annexectomia was realized. Histology showed narcotized ovary cells, with an increased number of vascular channels composed of thin walled vessels, whose wall consisted of an endothelium. This aspect evoked a cavernous hemangioma of the ovary. PMID:14613693

  8. Ovarian cavernous hemangioma in an 8-year-old girl.

    Science.gov (United States)

    Mirilas, P; Georgiou, G; Zevgolis, G

    1999-04-01

    The case of an ovarian cavernous hemangioma with torsion in an 8-year-old girl is described. Current literature records less than 50 cases of which only 8 are in children. The presenting symptoms of acute abdomen and the ultrasonographic study led to the preoperative diagnosis of torsion of an ovarian tumor. Salpingo-oophorectomy and appendicectomy were performed with an uneventful postoperative course. The histological pattern of the tumor was that of an entirely cavernous hemangioma. The case is reported in view of its rarity. PMID:10342121

  9. Large underground caverns - precedent experience study. Phase 2: cavern excavation engineering assessment. Sellafield specific conditions. V. 1: text

    International Nuclear Information System (INIS)

    Data compiled from various published and unpublished sources, on the construction of large underground caverns, has been drawn together here in order to produce a comparative reference database of precedent practice which could be used to inform engineers responsible for the preliminary design work for an underground radioactive disposal facility below NIREX's Sellafield site. This Global Survey, revealed the need for further research to clarify rock mass type and a suitable depth for the repository for the Sellafield site. The resulting geotechnical assessment of the rock mass is described in this volume. This work aimed to provide data on cavern constructability to NIREX's specific requirements and is divided into ten sections, including a survey of temporary mine openings, which was used to assess an upper boundary for the scan of any potential cavern repository. (UK)

  10. Cavernous sinus thrombosis and air embolism following surgery for acoustic neurinoma : a case report.

    Directory of Open Access Journals (Sweden)

    Nadkarni T

    2002-04-01

    Full Text Available A 55 year old male patient was operated on for a massive and vascular acoustic neurinoma in a sitting position. The tumor was completely excised. Post-operatively, the patient developed irritability and clinical features suggestive of contralateral cavernous sinus thrombosis. CT scan showed air within the dural walls of the cavernous sinus on the side of surgery. However, there was no radiological evidence of cavernous sinus thrombosis on the contralateral side. Cavernous sinus thrombosis as a post-surgery complication has not been reported. Air within the dural confines of the cavernous sinus has also not been observed or radiologically recorded in the literature.

  11. Caverns for neutrino physicists; Des cavernes pour les physiciens du neutrino

    Energy Technology Data Exchange (ETDEWEB)

    Duffaut, P

    2005-09-01

    Since more than 20 years, particle physicists are using underground facilities to catch cosmic neutrinos and to get rid of other parasitic cosmic radiations. The observation of significant numbers of neutrinos requires the use of large volume caverns at important depths. This article presents such existing facilities in the US, France, Italy, UK, Spain, Japan (Kamioka), Russia and India and the different projects in competition for the setting up of a mega-ton detector with a volume of 1 million m{sup 3} of water (DUSEL project in the US, MEMPHYS project in France, Hyperkamiokande in Japan). Several suitable underground spaces are available in these countries (abandoned mines, tunnels) but each has its advantages and drawbacks in terms of rock mechanics, access and seismicity. (J.S.)

  12. A contribution to the detection of subsoil movements above cavernous cavities in salt deposits

    International Nuclear Information System (INIS)

    The rock and soil movements above subsurface cavities depend on size, shape and depth of the caverns made for depositing different raw and waste materials. The fundamental relationships between cavernous convergencies and surface sinkage are illustrated by different cavern models with the help of published mathematical solutions. Separate caverns and fields or groups of caverns with or without filling are investigated. These solution models are applied to an already realized cavern project and the theoretical results are compared with the measuring results, with the intention to adapt the equations for determining convergencies and sinkages and to determine by estimation the free parameters of the mathematical model of sinkage. Models are proposed which shall help to determine the modification of convergency in dependency on the depth, to estimate the convergency in the excavation phase and to determine the limit angle in dependency on the depth. According to the regularities existing for cylindric caverns, this calculatory model is extended on ellipsoid cavities. (orig.)

  13. Hepatic cavernous hemangioma in cirrhotic liver: imaging findings

    International Nuclear Information System (INIS)

    To document the imaging findings of hepatic cavernous hemangioma detected in cirrhotic liver. The imaging findings of 14 hepatic cavernous hemangiomas in ten patients with liver cirrhosis were retrospectively analyzed. A diagnosis of hepatic cavernous hemangioma was based on the findings of two or more of the following imaging studies: MR, including contrast-enhanced dynamic imaging (n=10), dynamic CT (n=4), hepatic arteriography (n=9), and US (n=10). The mean size of the 14 hepatic hemangioma was 0.9 (range, 0.5-1.5) cm in the longest dimension. In 11 of these (79%), contrast-enhanced dynamic CT and MR imaging showed rapid contrast enhancement of the entire lesion during the early phase, and hepatic arteriography revealed globular enhancement and rapid filling-in. On contrast-enhanced MR images, three lesions (21%) showed partial enhancement until the 5-min delayed phases. US indicated that while three slowly enhancing lesions were homogeneously hyperechoic, 9 (82%) of 11 showing rapid enhancement were not delineated. The majority of hepatic cavernous hemangiomas detected in cirrhotic liver are small in size, and in many, hepatic arteriography and/or contrast-enhanced dynamic CT and MR imaging demonstrates rapid enhancement. US, however, fails to distinguish a lesion of this kind from its cirrhotic background. (author)

  14. Sensitivity analysis of influencing parameters in cavern stability

    Institute of Scientific and Technical Information of China (English)

    Abolfazl Abdollahipour; Reza Rahmannejad

    2012-01-01

    In order to analyze the stability of the underground rock structures,knowing the sensitivity of geomechanical parameters is important.To investigate the priority of these geomechanical properties in the stability of cavern,a sensitivity analysis has been performed on a single cavern in various rock mass qualities according to RMR using Phase 2.The stability of cavern has been studied by investigating the side wall deformation.Results showed that most sensitive properties are coefficient of lateral stress and modulus of deformation.Also parameters of Hoek-Brown criterion and σc have no sensitivity when cavern is in a perfect elastic state.But in an elasto-plastic state,parameters of Hoek-Brown criterion and σc affect the deformability; such effect becomes more remarkable with increasing plastic area.Other parameters have different sensitivities concerning rock mass quality (RMR).Results have been used to propose the best set of parameters for study on prediction of sidewall displacement.

  15. A Case of Brainstem Cavernous Angioma Presenting with Persistent Hiccups

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Arami

    2010-07-01

    Full Text Available "nIntractable hiccup most be considered as a symptom of underlying serious pathologies. We report a case of medulla oblongata cavernous angima presented with persistant hiccup and without any improvement during routine nonpharmacologic and pharmacologic treatment regimns. The patient is under our follow up visits and surgery is very high risk for this young girl.

  16. Orbital cavernous hemangiomas: ultrasound and magnetic resonance imaging evaluation.

    Science.gov (United States)

    Diamantopoulou, A; Damianidis, Ch; Kyriakou, V; Kotziamani, N; Emmanouilidou, M; Goutsaridou, F; Tsitouridis, I

    2010-03-01

    Cavernous hemangioma is the most common intraorbital lesion in adults. The aim of our study was to evaluate the magnetic resonance imaging (MRI) and ultrasound (US) characteristics of cavernous hemangioma and their role in the differential diagnosis of orbital tumors. Eight patients with orbital cavernous hemangiomas, five women and three men with a mean age of 48 years were examined in a period of six years. All patients underwent MRI examination and four patients were also evaluated by US. In all cases MRI depicted a well-defined intraconal tumor. The lesions were homogeneous, isointense to muscle on T1-weighted sequence and hyperintense to muscle on T2-weighted sequence in six patients. In one patient the mass was isointense on T1WI with heterogeneous signal intensity on T2WI and in one patient the lesion had heterogeneous signal intensity on both T1- and T2-weighted sequences. After intravenous contrast medium administration, the tumors showed initial inhomogeneous enhancement with progressive accumulation of contrast material on delayed images in seven patients and initial homogeneous enhancement in one patient. On ultrasonography, the orbital masses appeared slightly hyperechoic, heterogeneous with small areas of slow blood flow. The analysis of imaging characteristics of a well-defined intraconal lesion in an adult patient with painless progressive proptosis can be highly suggestive of the diagnosis of cavernous hemangioma. PMID:24148341

  17. Analysis of SPR salt cavern remedial leach program 2013.

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Paula D.; Gutierrez, Karen A.; Lord, David L.; Rudeen, David Keith [GRAM, Inc., Albuquerque, NM

    2013-09-01

    The storage caverns of the US Strategic Petroleum Reserve (SPR) exhibit creep behavior resulting in reduction of storage capacity over time. Maintenance of oil storage capacity requires periodic controlled leaching named remedial leach. The 30 MMB sale in summer 2011 provided space available to facilitate leaching operations. The objective of this report is to present the results and analyses of remedial leach activity at the SPR following the 2011 sale until mid-January 2013. This report focuses on caverns BH101, BH104, WH105 and WH106. Three of the four hanging strings were damaged resulting in deviations from normal leach patterns; however, the deviations did not affect the immediate geomechanical stability of the caverns. Significant leaching occurred in the toes of the caverns likely decreasing the number of available drawdowns until P/D ratio criteria are met. SANSMIC shows good agreement with sonar data and reasonably predicted the location and size of the enhanced leaching region resulting from string breakage.

  18. Cavernous hemangioma of rhinopharynx: our experience and review of literature

    Directory of Open Access Journals (Sweden)

    Testa Domenico

    2015-01-01

    Full Text Available Hemangiomas are benign tumors originating in the vascular tissues of skin, mucosa, muscles, glands, and bones. Although these tumors are common lesions of the head and neck, they rarely occur in the nasal cavity and paranasal sinuses. Cavernous haemangioma of the lateral wall of the nasopharynx has not previously been reported. We examined the clinical, radiological and therapeutic management of cavernous haemangioma of nasopharynx starting from a clinical case of a 26-year-old woman with a history of recurrent and conspicuous epistaxis and leftsided nasal associated severe obstruction. Nasopharynx examination, by flexible endoscopy, showed a cystic mass borne by the left side wall of the nasopharynx, in contact with the soft palate, covered by intact and regular mucosa. Contrast-enhanced computed tomography (CT scan, confirmed these findings and showed contextual lamellar calcifications and inhomogeneous enhancement. The nasal endoscopic approach (FESS, under general anesthesia, allowed removal of the mass, without complications, after careful hemostasis of arterial branches. It was possible to establish the precise site of origin of the tumor only during the surgical procedure. Histopathological study showed mucosa with extensive vascular proliferation, with framework of lacunar/cavernous haemangioma, also present at lamellar bone tissue level. An unusual site and an unspecific clinical appearance can make diagnosis and treatment of a cavernous hemangioma of the nasopharynx difficult. The nasal endoscopic technique proved to be reliable in terms of adequate exposure and visualization of the lesion, control of bleeding, and complete removal of the mass.

  19. Lowering End-cap YE-1 in the CMS cavern

    CERN Multimedia

    2008-01-01

    On Tuesday 22 January, the dance of the CMS end-caps came to an end with the lowering of YE-1, the heaviest of them all. After a spectacular lowering operation lsting ten hours, this mammoth component completed the 100-metre descent and was gently placed on the floor of the CMS cavern to the applause of the many onlookers.

  20. Valuation of gas stored in salt cavern facilities

    Energy Technology Data Exchange (ETDEWEB)

    Bond, Michael A. [St. Mary' s University, TX (United States); Grant, Floyd H. [Purdue University, IN (United States)

    2008-07-01

    Since natural gas production is relatively inelastic towards demand in the short term, underground storage is used as a buffer against periods of high demand. Of the three most common storage facility types, depleted reservoirs, aquifers and manmade salt caverns, the latter is the most costly to develop. The challenge then is to maximize profits through efficient operation, well-timed injection and withdrawal of gas. The valuation of a commodity in storage is a challenging problem and has been the subject of study for decades. We investigate selected existing valuation approaches and look for ways to leverage salt-cavern-specific physical characteristics for financial advantage. The basis for our valuation is the Black-Scholes model for pricing options. Then, applying Monte-Carlo methods and simulation, we model combinations of characteristics in multi-cavern facilities and their impact on profitability. We describe the theory behind our work and our analytical framework and provide numerical results of our analysis. Our approach offers increased efficiency in salt-cavern gas storage facility operations. (author)

  1. Novel Technique for the UX15 Cavern Vault Support System

    CERN Document Server

    Rammer, H

    2000-01-01

    The overall LHC project schedule requires the civil engineering work to begin before the final LEP shutdown. The new caverns for the ATLAS experiment will be built in and around the existing underground structures at point 1. In order to make the best possible use of the time available for the LHC civil engineering before the shutdown of LEP, a particular arrangement for the construction of the UX15 cavern vault has been developed. The basic concept of this arrangement consists of the excavation of the cavern top heading and the installation of the concrete vault immediately afterwards, prior to the subsequent bench excavation after LEP shutdown. A temporary support of the dead weight of the concrete roof will be achieved by the suspension of the roof by 38 no. pre-stressed ground anchors of 225 tons capacity each. This support system will work up to the construction of the cavern base slab and walls and the completion of the permanent concrete lining.

  2. Numerical Simulations of Leakage from Underground LPG Storage Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Hajime; Pruess, Karsten

    2004-09-01

    To secure a stable supply of petroleum gas, underground storage caverns for liquified petroleum gas (LPG) are commonly used in many countries worldwide. Storing LPG in underground caverns requires that the surrounding rock mass remain saturated with groundwater and that the water pressure be higher than the liquid pressure inside the cavern. In previous studies, gas containment criteria for underground gas storage based on hydraulic gradient and pressure have been discussed, but these studies do not consider the physicochemical characteristics and behavior of LPG such as vaporization and dissolution in groundwater. Therefore, while these studies are very useful for designing storage caverns, they do not provide better understanding of the either the environmental effects of gas contamination or the behavior of vaporized LPG. In this study, we have performed three-phase fluid flow simulations of gas leakage from underground LPG storage caverns, using the multiphase multicomponent nonisothermal simulator TMVOC (Pruess and Battistelli, 2002), which is capable of solving the three-phase nonisothermal flow of water, gas, and a multicomponent mixture of volatile organic chemicals (VOCs) in multidimensional heterogeneous porous media. A two-dimensional cross-sectional model resembling an actual underground LPG facility in Japan was developed, and gas leakage phenomena were simulated for three different permeability models: (1) a homogeneous model, (2) a single-fault model, and (3) a heterogeneous model. In addition, the behavior of stored LPG was studied for the special case of a water curtain suddenly losing its function because of operational problems, or because of long-term effects such as clogging of boreholes. The results of the study indicate the following: (1) The water curtain system is a very powerful means for preventing gas leakage from underground storage facilities. By operating with appropriate pressure and layout, gas containment can be ensured. (2

  3. Fungal communities on speleothem surfaces in Kartchner Caverns, Arizona, USA

    Directory of Open Access Journals (Sweden)

    Vaughan Michael J.

    2011-01-01

    Full Text Available Kartchner Caverns, located near Benson, Arizona, USA, is an active carbonate cave that serves as the major attraction for Kartchner Caverns State Park. Low-impact development and maintenance have preserved prediscovery macroscopic cavern features and minimized disturbances to biological communities within the cave.. The goal of this study was to examine fungal diversity in Kartchner Caverns on actively-forming speleothem surfaces. Fifteen formations were sampled from five sites across the cave. Richness was assessed using standard culture-based fungal isolation techniques. A culture-independent analysis using denaturing gradient gel electrophoresis (DGGE was used to assay evidence of community homogeneity across the cave through the separation of 18S rDNA amplicons from speleothem community DNA. The culturing effort recovered 53 distinct morphological taxonomic units (MTUs, corresponding to 43 genetic taxonomic units (GTUs that represented 21 genera. From the observed MTU accumulation curve and the projected total MTU richness curve, it is estimated that 51 percent of the actual MTU richness was recovered. The most commonly isolated fungi belonged to the genera Penicillium, Paecilomyces, Phialophora, and Aspergillus.This culture- based analysis did not reveal significant differences in fungal richness or number of fungi recovered across sites. Cluster analysis using DGGE band profiles did not reveal distinctive groupings of speleothems by sample site. However, canonical correspondence analysis (CCA analysis of culture-independent DGGE profiles showed a significant effect of sampling site and formation type on fungal community structure.Taken together, these results reveal that diverse fungal communities exist on speleothem surfaces in Kartchner Caverns, and that these communities are not uniformly distributed spatially. Analysis of sample saturation indicated that more sampling depth is required to uncover the full scale of mycological richness

  4. Preliminary technical and legal evaluation of disposing of nonhazardous oil field waste into salt caverns

    Energy Technology Data Exchange (ETDEWEB)

    Veil, J.; Elcock, D.; Raivel, M.; Caudle, D.; Ayers, R.C. Jr.; Grunewald, B.

    1996-06-01

    Caverns can be readily formed in salt formations through solution mining. The caverns may be formed incidentally, as a result of salt recovery, or intentionally to create an underground chamber that can be used for storing hydrocarbon products or compressed air or disposing of wastes. The purpose of this report is to evaluate the feasibility, suitability, and legality of disposing of nonhazardous oil and gas exploration, development, and production wastes (hereafter referred to as oil field wastes, unless otherwise noted) in salt caverns. Chapter 2 provides background information on: types and locations of US subsurface salt deposits; basic solution mining techniques used to create caverns; and ways in which salt caverns are used. Later chapters provide discussion of: federal and state regulatory requirements concerning disposal of oil field waste, including which wastes are considered eligible for cavern disposal; waste streams that are considered to be oil field waste; and an evaluation of technical issues concerning the suitability of using salt caverns for disposing of oil field waste. Separate chapters present: types of oil field wastes suitable for cavern disposal; cavern design and location; disposal operations; and closure and remediation. This report does not suggest specific numerical limits for such factors or variables as distance to neighboring activities, depths for casings, pressure testing, or size and shape of cavern. The intent is to raise issues and general approaches that will contribute to the growing body of information on this subject.

  5. Sensitivity of storage field performance to geologic and cavern design parameters in salt domes.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L. (Sandia National Laboratories, Albuquerque, NM); Park, Byoung Yoon

    2009-03-01

    A sensitivity study was performed utilizing a three dimensional finite element model to assess allowable cavern field sizes for strategic petroleum reserve salt domes. A potential exists for tensile fracturing and dilatancy damage to salt that can compromise the integrity of a cavern field in situations where high extraction ratios exist. The effects of salt creep rate, depth of salt dome top, dome size, caprock thickness, elastic moduli of caprock and surrounding rock, lateral stress ratio of surrounding rock, cavern size, depth of cavern, and number of caverns are examined numerically. As a result, a correlation table between the parameters and the impact on the performance of storage field was established. In general, slower salt creep rates, deeper depth of salt dome top, larger elastic moduli of caprock and surrounding rock, and a smaller radius of cavern are better for structural performance of the salt dome.

  6. Bilateral Persistent Trigeminal Arteries with Unilateral Trigeminal Artery to Cavernous Sinus Fistula: A Case Report

    OpenAIRE

    Chen, David; Chen, Chi-Jen; Chen, Jiann-Jy; Tseng, Ying-Chi; Hsu, Hui-Ling; Ku, Jan-Wen

    2013-01-01

    A 59-year-old man who denied a history of trauma presented with left pulsatile tinnitus and left orbital swelling for six months. Digital subtraction angiography showed a left persistent trigeminal artery (PTA) with a trigeminal artery to cavernous sinus (trigeminal-cavernous sinus) fistula and a right PTA. Transarterial detachable coil embolization of the left trigeminal-cavernous sinus fistula was performed, and the symptoms subsided. There has been no report of bilateral PTAs with a sponta...

  7. Cluster Headache Secondary to Macroprolactinoma with Ipsilateral Cavernous Sinus Invasion

    Directory of Open Access Journals (Sweden)

    M. J. Levy

    2012-01-01

    Full Text Available We present a 25 year-old man with episodic cluster headache that was refractory to all standard pharmacological prophylactic and abortive treatments. Because of the lack of response, an MRI brain was performed which showed a large pituitary tumour with ipsilateral cavernous sinus invasion. The serum prolactin was significantly elevated at 54,700 miU/L (50–400 confirming a macro-prolactinoma. Within a few days of cabergoline therapy the headache resolved. He continues to be headache free several years after starting the dopamine agonist. This case highlights the importance of imaging the pituitary fossa in patients with refractory cluster headache, It also raises the potential anatomical importance of the cavernous sinus in pituitary-associated headache.

  8. Cataract surgery in a case of carotid cavernous fistula

    Directory of Open Access Journals (Sweden)

    Akshay Gopinathan Nair

    2014-01-01

    Full Text Available A carotid-cavernous fistula (CCF is an abnormal communication between the cavernous sinus and the carotid arterial system. The ocular manifestations include conjunctival chemosis, proptosis, globe displacement, raised intraocular pressure and optic neuropathy. Although management of CCF in these patients is necessary, the ophthalmologist may also have to treat other ocular morbidities such as cataract. Cataract surgery in patients with CCF may be associated with many possible complications, including suprachoroidal hemorrhage. We describe cataract extraction surgery in 60-year-old female with bilateral spontaneous low-flow CCF. She underwent phacoemulsification via a clear corneal route under topical anesthesia and had an uneventful postoperative phase and recovered successfully. Given the various possible ocular changes in CCF, one must proceed with an intraocular surgery with caution. In this communication, we wish to describe the surgical precautions and the possible pitfalls in cataract surgery in patients with CCF.

  9. Cavernous Angioma of the Corpus Callosum Presenting with Acute Psychosis

    OpenAIRE

    Giacomo Pavesi; Francesco Causin; Alberto Feletti

    2014-01-01

    Psychiatric symptoms may occasionally be related to anatomic alterations of brain structures. Particularly, corpus callosum lesions seem to play a role in the change of patients’ behavior. We present a case of a sudden psychotic attack presumably due to a hemorrhagic cavernous angioma of the corpus callosum, which was surgically removed with complete resolution of symptoms. Although a developmental defect like agenesis or lipoma is present in the majority of these cases, a growing lesion of t...

  10. Cavernous Hemangioma of the Rib: A Rare Diagnosis

    Directory of Open Access Journals (Sweden)

    Stavros Gourgiotis

    2010-01-01

    Full Text Available Hemangioma of the rib is an uncommon benign vascular tumour. A case of rib hemangioma in a 29-year-old woman is presented. Chest roentgenogram and computed tomography revealed a mass along the inner surface of the 7th left rib with bone destruction. She underwent resection of the 7th rib. The pathologic diagnosis was cavernous hemangioma. Hemangiomas of the rib are rare tumours but should be kept in mind in the differential diagnosis of rib tumours.

  11. Treatment of Cavernous Sinus Tumors with Linear Accelerator Radiosurgery

    OpenAIRE

    Chang, Steven D; Doty, James R; Martin, David P.; Hancock, Steven L.; Adler, John R.

    1999-01-01

    Since 1989, 79 patients with benign or malignant cavernous sinus tumors, have been treated at Stanford University with linear accelerator (linac) radiosurgery. Radiosurgery has been used as (1) a planned second-stage procedure for residual tumor following surgery, (2) primary treatment for patients whose medical conditions preclude surgery, (3) palliation of malignant lesions, and (4) definitive treatment for small, well-localized, poorly accessible tumors. Mean patient age was 52 years (rang...

  12. Cavernous hemangioma of the adrenal gland: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Eui Dong; Cho, Jae Min; You, Jin Jong; Choi, Dae Seob; Ryoo, Jae Wook [Gyeongsang National University College of Medicine, Jinju (Korea, Republic of)

    2005-07-15

    Hemangiomas are rare benign tumors of the adrenal gland. We report here on the CT findings of a cavernous hemangioma of the right adrenal gland. The CT revealed a well-delineated adrenal mass having an internal necrotic portion and tiny peripheral calcifications. After administration of the contrast media, the tumor showed peripheral enhancement on the arterial phase, and this was followed by progressive centripetal fill-in.

  13. Is the Gamma Knife Treatment of Cerebral Cavernous Angioma Effective?

    OpenAIRE

    Wenchuan, Zhang; Wenxiang, Zhong; Xuhui, Wang

    2013-01-01

    The treatment of cerebral cavernous angioma (CCA) has caused great controversy. In the case of recurrent haemorrhage, frequent epileptic attacks, clear dysneuria, etc., and by taking into consideration focal positions, number of foci, and conditions conducive to operations, it is our opinion that excision of CCA foci is the first choice to cure the disease. Controversy regarding the gamma knife treatment of CCA has existed for a long time. The main reason behind this i...

  14. Configuration of Fibrous and Adipose Tissues in the Cavernous Sinus

    Science.gov (United States)

    Liang, Liang; Gao, Fei; Xu, Qunyuan; Zhang, Ming

    2014-01-01

    Objective Three-dimensional anatomical appreciation of the matrix of the cavernous sinus is one of the crucial necessities for a better understanding of tissue patterning and various disorders in the sinus. The purpose of this study was to reveal configuration of fibrous and adipose components in the cavernous sinus and their relationship with the cranial nerves and vessels in the sinus and meningeal sinus wall. Materials and Methods Nineteen cadavers (8 females and 11 males; age range, 54–89 years; mean age, 75 years) were prepared as transverse (6 sets), coronal (3 sets) and sagittal (10 sets) plastinated sections that were examined at both macroscopic and microscopic levels. Results Two types of the web-like fibrous networks were identified and localized in the cavernous sinus. A dural trabecular network constituted a skeleton-frame in the sinus and contributed to the sleeves of intracavernous cranial nerves III, IV, V1, V2 and VI. A fine trabecular network, or adipose tissue, was the matrix of the sinus and was mainly distributed along the medial side of the intracavernous cranial nerves, forming a dumbbell-shaped adipose zone in the sinus. Conclusions This study revealed the nature, fine architecture and localization of the fine and dural trabecular networks in the cavernous sinus and their relationship with intracavernous cranial nerves and vessels. The results may be valuable for better understanding of tissue patterning in the cranial base and better evaluation of intracavernous disorders, e.g. the growth direction and extent of intracavernous tumors. PMID:24586578

  15. Bilateral Persistent Trigeminal Arteries with Unilateral Trigeminal Artery to Cavernous Sinus Fistula

    Science.gov (United States)

    Chen, David; Chen, Chi-Jen; Chen, Jiann-Jy; Tseng, Ying-Chi; Hsu, Hui-Ling; Ku, Jan-Wen

    2013-01-01

    Summary A 59-year-old man who denied a history of trauma presented with left pulsatile tinnitus and left orbital swelling for six months. Digital subtraction angiography showed a left persistent trigeminal artery (PTA) with a trigeminal artery to cavernous sinus (trigeminal-cavernous sinus) fistula and a right PTA. Transarterial detachable coil embolization of the left trigeminal-cavernous sinus fistula was performed, and the symptoms subsided. There has been no report of bilateral PTAs with a spontaneous fistula connected from one PTA to the ipsilateral cavernous sinus. This paper reports such a rare circumstance. PMID:24070083

  16. Bilateral persistent trigeminal arteries with unilateral trigeminal artery to cavernous sinus fistula. A case report.

    Science.gov (United States)

    Chen, David; Chen, Chi-Jen; Chen, Jiann-Jy; Tseng, Ying-Chi; Hsu, Hui-Ling; Ku, Jan-Wen

    2013-09-01

    A 59-year-old man who denied a history of trauma presented with left pulsatile tinnitus and left orbital swelling for six months. Digital subtraction angiography showed a left persistent trigeminal artery (PTA) with a trigeminal artery to cavernous sinus (trigeminal-cavernous sinus) fistula and a right PTA. Transarterial detachable coil embolization of the left trigeminal-cavernous sinus fistula was performed, and the symptoms subsided. There has been no report of bilateral PTAs with a spontaneous fistula connected from one PTA to the ipsilateral cavernous sinus. This paper reports such a rare circumstance. PMID:24070083

  17. Transcatheter Arterial Embolization of Two Symptomatic Giant Cavernous Hemangiomas of the Liver

    International Nuclear Information System (INIS)

    Cavernous hemangiomas are usually asymptomatic; however, a small percentage may cause symptoms. This case report discusses palliation by transcatheter arterial embolization with polyvinyl alcohol particles

  18. Isolated Cavernous Hemangioma of the Conjunctiva: Case Report and Review of Literature

    Directory of Open Access Journals (Sweden)

    Hossein Aghaei

    2013-12-01

    Full Text Available Purpose: To report clinical and pathologic result of a young patient with isolated cavernous hemangioma of conjunctiva Case report: A 26-year-old man who presented with smooth, red, lobular surface mass was seen in the bulbar conjunctiva in temporal side with engorged episcleral and conjunctival vessels around the lesion. Excisional biopsy was performed. Pathologist confirmed the diagnosis of cavernous hemangioma of bulbar conjunctiva. Patient was followed-up for 18 months without recurrence and cosmetic feature was acceptable. Conclusion: Ocular surface is an uncommon site of cavernous hemangioma and isolated conjunctival cavernous hemangioma is rare, but this tumor is considered as a differential diagnosis of conjunctival vascular tumors.

  19. The role of Tc-99m RBC scintigraphy in the differential diagnosis of orbital cavernous hemangioma.

    Science.gov (United States)

    Sayit, E; Durak, I; Capakaya, G; Yilmaz, M; Durak, H

    2001-04-01

    The cavernous hemangioma is the most common benign orbital tumor in adults. Its presentation is during the forth to fifth decades with a slowly progressive unilateral proptosis. Intraconal cavernous hemangiomas may be difficult to differentiate from other intraconal lesions such as schwannomas, meningiomas and hemangiopericytomas. We report a case of orbital cavernous hemangioma diagnosed by Tc-99m RBC scintigraphy. Tc-99m RBC scintigraphy revealed a typical scintigraphic pattern in which there is intense focally increased uptake on the delayed image. We conclude that Tc-99m RBC scintigraphy can be a useful method in the differential diagnosis of orbital cavernous hemangioma as in hepatic hemangioma. PMID:11448074

  20. Isolated oculomotor nerve palsy caused by cavernous sinus dural arteriovenous fistula: Case report

    International Nuclear Information System (INIS)

    Cavernous dural arteriovenous fistula (DAVF), which usually presents with conjunctival injection, proptosis, loss of visual acuity, and ophthalmoplegia, is a rare cause of ophthalmoplegia. Thus, it may be overlooked when the typical symptoms are lacking. There have been some cavernous DAVF case reports presenting with isolated oculomotor, abducens and trochlear nerve palsy. We report a patient presenting with isolated oculomotor palsy, caused by cavernous DAVF, which was treated by transvenous coil embolization. This case suggests that cavernous DAVF should be considered in the differential diagnosis of isolated oculomotor nerve palsy and for which case - selective angiography and embolization may be helpful in reaching a diagnosis and providing a guide for optimal treatment

  1. Isolated oculomotor nerve palsy caused by cavernous sinus dural arteriovenous fistula: Case report

    Energy Technology Data Exchange (ETDEWEB)

    Ihn, Yon Kwon; Jung, Won Sang [The Catholic Univ. of Korea, Suwon (Korea, Republic of); Kim, Bum Soo [The Catholic Univ. of Korea, Seoul (Korea, Republic of)

    2012-10-15

    Cavernous dural arteriovenous fistula (DAVF), which usually presents with conjunctival injection, proptosis, loss of visual acuity, and ophthalmoplegia, is a rare cause of ophthalmoplegia. Thus, it may be overlooked when the typical symptoms are lacking. There have been some cavernous DAVF case reports presenting with isolated oculomotor, abducens and trochlear nerve palsy. We report a patient presenting with isolated oculomotor palsy, caused by cavernous DAVF, which was treated by transvenous coil embolization. This case suggests that cavernous DAVF should be considered in the differential diagnosis of isolated oculomotor nerve palsy and for which case - selective angiography and embolization may be helpful in reaching a diagnosis and providing a guide for optimal treatment.

  2. Structural analysis of the West Hackbery No. 6 SPR storage cavern

    Energy Technology Data Exchange (ETDEWEB)

    Benzley, S.E.

    1980-08-01

    Four separate structural analyses of the West Hackberry No. 6 SPR storage cavern are presented. One analysis covers the creep response of the cavern beginning shortly before the time when an accidental fire occurred and proceeding through the cavern recertification pressure test. The second analysis models the surface uplife that is expected during the same pressure test. The third and fourth numerical studies investigate the structural response of West Hackberry No. 6 to slabbing and a rapid pressure drop. All analyses indicate that this cavern should be structurally stable for the conditions assumed.

  3. Carotid Cavernous Fistula Associated with Persistent Trigeminal Artery

    Science.gov (United States)

    Hurst, Robert W.; Howard, Robert S.; Zager, Eric

    1998-01-01

    Carotid-cavernous fistula (CCF) associated with persistent trigeminal artery (PTA) is a rare but important clinical entity. We present a case treated by microcoil embolization with preservation of internal carotid, PTA, and hasilar artery flow following embolization. A 62-year-old female developed pulsatile tinnitus followed by left eye proptosis and diplopia. Examination revealed a cranial nerve VI palsy and an objective bruit over the left orbit. Angiographic evaluation revealed a carotid cavernous fistula originating from a persistent trigeminal artery. Placement of a detachable balloon across the fistula site while preserving the PTA proved impossible, and the fistula was treated with microcoils following placement of a microcatheter across the fistula into the cavernous sinus. Complete closure of the fistula was followed by resolution of the patient's symptoms. Preservation of all major vessels including the PTA was accomplished through the use of coil embolization. Careful evaluation of the angiogram is necessary to identify PTA associated with a CCF. Previous reports have described treatment of CCF with PTA by surgical or balloon ocolusion, some involving sacrifice of the PTA. Examination of the relevant embryology and anatomy reveals, however, that occlusion of the PTA must be approached with caution due to potential supply to the posterior circulation. ImagesFigure 1 PMID:17171071

  4. Bryan Mound SPR cavern 113 remedial leach stage 1 analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Rudeen, David Keith [GRAM, Inc., Albuquerque, NM; Weber, Paula D.; Lord, David L.

    2013-08-01

    The U.S. Strategic Petroleum Reserve implemented the first stage of a leach plan in 2011-2012 to expand storage volume in the existing Bryan Mound 113 cavern from a starting volume of 7.4 million barrels (MMB) to its design volume of 11.2 MMB. The first stage was terminated several months earlier than expected in August, 2012, as the upper section of the leach zone expanded outward more quickly than design. The oil-brine interface was then re-positioned with the intent to resume leaching in the second stage configuration. This report evaluates the as-built configuration of the cavern at the end of the first stage, and recommends changes to the second stage plan in order to accommodate for the variance between the first stage plan and the as-built cavern. SANSMIC leach code simulations are presented and compared with sonar surveys in order to aid in the analysis and offer projections of likely outcomes from the revised plan for the second stage leach.

  5. Outcome of LINAC radiosurgery for a cavernous angioma

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Se Mie; Chie, Eui Kyu; Kim, Il Han; Ha, Sung Whan; Park, Charn Il [College of Medicine, Seoul National Univ., Seoul (Korea, Republic of); Park, Suk Won [College of Medicine, Halym Univ., Seoul (Korea, Republic of)

    2003-03-01

    To establish the role of stereotactic radiosurgery using a linear accelerator for the treatment of patients with cavernous angioma. Between February 1995 and May 1997, 11 patients with cavernous angioma were treated with stereotactic radiosurgery using a linear accelerator. Diagnoses were based on the magnetic resonance imaging in 8 patients, and the histological in 3. The vascular lesions were located in the brainstem (5 cases), cerebellum (2 cases) thalamus (1 case) and cerebrum (3 cases), The clinical presentation at onset included previous intracerebral hemorrhages (9 cases) and seizures (2 cases). All patients were treated with a linac-based radiosurgery. The median dose of radiation delivered was 16 Gy ranging from 14 to 24 Gy, which was typically prescribed to the 80% isodose surface (range 50-80%), corresponding to the periphery of the lesion with a single isocenter. Ten patients were followed-up. The median follow-up was 49 months ranging from 8 to 73 months, during which time two patients developed an intracerebral hemorrhage, 1 at 8 months, with the other at 64 months post radiosurgery. One patient developed neurological deficit after radiosurgery, and two developed an edema on the T2 weighted images of the MRI surrounding the radiosurgical target. The use of stereotactic radiosurgery in the treatment of a cavernous angioma may be effective in the prevention of rebleeding, and can be safely delivered. However, a longer follow-up period will be required.

  6. Role of radiosurgery in the management of cavernous sinus meningiomas

    International Nuclear Information System (INIS)

    Objective - To provide our early experience and philosophy in the utility of radiosurgery in the management of cavernous sinus meningiomas. Methods - Twenty-five consecutive cases with cavernous sinus meningiomas treated between 1990 and 1995 were reviewed. Three cases were treated with gamma-knife radiosurgery, 15 with preceding surgery and gamma knife, 7 with surgery. Mean follow-up following radiosurgery and surgery were 34.8 and 25.4 months, respectively. Results - The 5-year actuarial tumor control rate following radiosurgery was 85.7% and tumor remission rate was 61.4%. Permanent neurological deterioration after radiosurgery was seen in 1 case (5.9%), whereas newly developed or worsened neurological deficits permanently persisted in 59.1% of patients after surgery. There was a clear correlation between surgical radiocality and postoperative morbidity rate. Conclusions - Gamma-knife radiosurgery is a valuable addition to surgical removal in the treatment of cavernous sinus meningiomas. Combination of non-radical resection and subsequent radiosurgery in recommended to improve treatment-associated morbidity. (au)

  7. Gas hydrates in gas storage caverns; Gashydrate bei der Gaskavernenspeicherung

    Energy Technology Data Exchange (ETDEWEB)

    Groenefeld, P. [Kavernen Bau- und Betriebs-GmbH, Hannover (Germany)

    1997-12-31

    Given appropriate pressure and temperature conditions the storage of natural gas in salt caverns can lead to the formation of gas hydrates in the producing well or aboveground operating facilities. This is attributable to the stored gas becoming more or less saturated with water vapour. The present contribution describes the humidity, pressure, and temperature conditions conducive to gas hydrate formation. It also deals with the reduction of the gas removal capacity resulting from gas hydrate formation, and possible measures for preventing hydrate formation such as injection of glycol, the reduction of water vapour absorption from the cavern sump, and dewatering of the cavern sump. (MSK) [Deutsch] Bei der Speicherung von Erdgas in Salzkavernen kann es unter entsprechenden Druck- und Temperaturverhaeltnissen zur Gashydratbildung in den Foerdersonden oder obertaegigen Betriebseinrichtungen kommen, weil sich das eingelagerte Gas mehr oder weniger mit Wasserdampf aufsaettigt. Im Folgenden werden die Feuchtigkeits-, Druck- und Temperaturbedingungen, die zur Hydratbildung fuehren erlaeutert. Ebenso werden die Verringerung der Auslagerungskapazitaet durch die Hydratbildung, Massnahmen zur Verhinderung der Hydratbildung wie die Injektion von Glykol, die Verringerung der Wasserdampfaufnahme aus dem Kavernensumpf und die Entwaesserung der Kavernensumpfs selbst beschrieben.

  8. Fractionated Proton Radiotherapy for Benign Cavernous Sinus Meningiomas

    Energy Technology Data Exchange (ETDEWEB)

    Slater, Jerry D., E-mail: jdslater@dominion.llumc.edu [Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, CA (United States); Loredo, Lilia N.; Chung, Arthur; Bush, David A.; Patyal, Baldev [Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, CA (United States); Johnson, Walter D.; Hsu, Frank P.K. [Department of Neurosurgery, Loma Linda University Medical Center, Loma Linda, CA (United States); Slater, James M. [Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, CA (United States)

    2012-08-01

    Purpose: To evaluate the efficacy of fractionated proton radiotherapy for a population of patients with benign cavernous sinus meningiomas. Methods and Materials: Between 1991 and 2002, 72 patients were treated at Loma Linda University Medical Center with proton therapy for cavernous sinus meningiomas. Fifty-one patients had biopsy or subtotal resection; 47 had World Health Organization grade 1 pathology. Twenty-one patients had no histologic verification. Twenty-two patients received primary proton therapy; 30 had 1 previous surgery; 20 had more than 1 surgery. The mean gross tumor volume was 27.6 cm{sup 3}; mean clinical target volume was 52.9 cm{sup 3}. Median total doses for patients with and without histologic verification were 59 and 57 Gy, respectively. Mean and median follow-up periods were 74 months. Results: The overall 5-year actuarial control rate was 96%; the control rate was 99% in patients with grade 1 or absent histologic findings and 50% for those with atypical histology. All 21 patients who did not have histologic verification and 46 of 47 patients with histologic confirmation of grade 1 tumor demonstrated disease control at 5 years. Control rates for patients without previous surgery, 1 surgery, and 2 or more surgeries were 95%, 96%, and 95%, respectively. Conclusions: Fractionated proton radiotherapy for grade 1 cavernous sinus meningiomas achieves excellent control rates with minimal toxicities, regardless of surgical intervention or use of histologic diagnosis. Disease control for large lesions can be achieved by primary fractionated proton therapy.

  9. Review of applicable technology: solution mining of caverns in salt domes to serve as repositories for radioactive wastes

    International Nuclear Information System (INIS)

    There is an abundance of salt domes in the Gulf Coastal region. Advances in leaching technology and cavern shape control make it possible to build large caverns with configurations approaching teardrops, cylinders, and spheres. Fenix and Scisson has designed and constructed several dozen caverns in sizes up to three million barrels (16.8 million cubic feet). It is now within current technological bounds to evacuate the brine left in the cavern following construction, dehumidify the cavern atmosphere and supply conditioned cavern ventilation. The state-of-the-art in drilling large diameter holes has advanced to the point that it is now possible to drill 120-in. holes as deep as 6,000 ft and 144-in. holes to lesser depths. Additional research is needed in the area of cavern stability. Cavern shrinkage rates are known to increase with depth because of lower salt strengths at higher pressures and temperatures

  10. Feasibility analysis of using abandoned salt caverns for large-scale underground energy storage in China

    International Nuclear Information System (INIS)

    Highlights: • A method is proposed for the evaluation of using an abandoned salt cavern for energy (natural gas) storage. • A feasibility analysis is given of China’s first UGS (Underground Gas Storage) facility using an abandoned salt cavern. • Numerical modeling has been used to investigate mechanical safety of a gas pressurized cavern. • Chinese abandoned salt caverns show good feasibility of being converted to UGSs. • China’s bedded rock salt can meet the requirements for UGS. - Abstract: Rock salt in China is primarily bedded salt, usually composed of many thin salt layers and interlayers (e.g. anhydrite, mudstone, and glauberite). Thus, the feasibility analysis of abandoned salt caverns located in salt beds to be used as Underground Gas Storage (UGS) facilities is full of challenges. In this paper, we introduce the feasibility analysis of China’s first salt cavern gas storage facility using an abandoned salt cavern. The cavern is located in Jintan city, Jiangsu province, China. The mechanical properties and permeability of the bedded salts are obtained by experiments. Based on the results of the analyses, it appears to be quite feasible to convert the abandoned salt caverns of Jintan city to UGS facilities. The stability of the cavern is evaluated by the 3D geomechanical numerical simulations, and the operating parameters are proposed accordingly. Results indicate that the maximum volume shrinkage of the cavern is less than 25% and the maximum deformations are less than 2% of the caverns’ maximum diameters after operating for 20 years. It is recommended that the weighted average internal gas pressure be maintained as 11 MPa to control the extent of the plastic zones to a safe level. Safety factors decrease with operating time, especially those of the interface between rock salt and mudstone layers decrease significantly. Effective strain is generally greater than 2%, and locally is greater than 3% after operating 20 years. The maximum

  11. Geomechanical Analysis and Design Considerations for Thin-Bedded Salt Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Michael S. Bruno

    2005-06-15

    The bedded salt formations located throughout the United States are layered and interspersed with non-salt materials such as anhydrite, shale, dolomite and limestone. The salt layers often contain significant impurities. GRI and DOE have initialized this research proposal in order to increase the gas storage capabilities by providing operators with improved geotechnical design and operating guidelines for thin bedded salt caverns. Terralog has summarized the geologic conditions, pressure conditions, and critical design factors that may lead to: (1) Fracture in heterogeneous materials; (2) Differential deformation and bedding plane slip; (3) Propagation of damage around single and multiple cavern; and (4) Improved design recommendations for single and multiple cavern configurations in various bedded salt environments. The existing caverns within both the Permian Basin Complex and the Michigan and Appalachian Basins are normally found between 300 m to 1,000 m (1,000 ft to 3,300 ft) depth depending on local geology and salt dissolution depth. Currently, active cavern operations are found in the Midland and Anadarko Basins within the Permian Basin Complex and in the Appalachian and Michigan Basins. The Palo Duro and Delaware Basins within the Permian Basin Complex also offer salt cavern development potential. Terralog developed a number of numerical models for caverns located in thin bedded salt. A modified creep viscoplastic model has been developed and implemented in Flac3D to simulate the response of salt at the Permian, Michigan and Appalachian Basins. The formulation of the viscoplastic salt model, which is based on an empirical creep law developed for Waste Isolation Pilot Plant (WIPP) Program, is combined with the Drucker-Prager model to include the formation of damage and failure. The Permian salt lab test data provided by Pfeifle et al. 1983, are used to validate the assumptions made in the material model development. For the actual cavern simulations two

  12. Risk assessment of nonhazardous oil-field waste disposal in salt caverns.

    Energy Technology Data Exchange (ETDEWEB)

    Elcock, D.

    1998-03-05

    In 1996, Argonne National Laboratory (ANL) conducted a preliminary technical and legal evaluation of disposing of nonhazardous oil-field wastes (NOW) into salt caverns. Argonne determined that if caverns are sited and designed well, operated carefully, closed properly, and monitored routinely, they could be suitable for disposing of oil-field wastes. On the basis of these findings, Argonne subsequently conducted a preliminary evaluation of the possibility that adverse human health effects (carcinogenic and noncarcinogenic) could result from exposure to contaminants released from the NOW disposed of in domal salt caverns. Steps used in this evaluation included the following: identifying potential contaminants of concern, determining how humans could be exposed to these contaminants, assessing contaminant toxicities, estimating contaminant intakes, and calculating human cancer and noncancer risk estimates. Five postclosure cavern release scenarios were assessed. These were inadvertent cavern intrusion, failure of the cavern seal, failure of the cavern through cracks, failure of the cavern through leaky interbeds, and a partial collapse of the cavern roof. Assuming a single, generic, salt cavern and generic oil-field wastes, potential human health effects associated with constituent hazardous substances (arsenic, benzene, cadmium, and chromium) were assessed under each of these scenarios. Preliminary results provided excess cancer risk and hazard index (referring to noncancer health effects) estimates that were well within the US Environmental Protection Agency (EPA) target range for acceptable exposure risk levels. These results led to the preliminary conclusion that from a human health perspective, salt caverns can provide an acceptable disposal method for nonhazardous oil-field wastes.

  13. Risk assessment of nonhazardous oil-field waste disposal in salt caverns

    International Nuclear Information System (INIS)

    In 1996, Argonne National Laboratory (ANL) conducted a preliminary technical and legal evaluation of disposing of nonhazardous oil-field wastes (NOW) into salt caverns. Argonne determined that if caverns are sited and designed well, operated carefully, closed properly, and monitored routinely, they could be suitable for disposing of oil-field wastes. On the basis of these findings, Argonne subsequently conducted a preliminary evaluation of the possibility that adverse human health effects (carcinogenic and noncarcinogenic) could result from exposure to contaminants released from the NOW disposed of in domal salt caverns. Steps used in this evaluation included the following: identifying potential contaminants of concern, determining how humans could be exposed to these contaminants, assessing contaminant toxicities, estimating contaminant intakes, and calculating human cancer and noncancer risk estimates. Five postclosure cavern release scenarios were assessed. These were inadvertent cavern intrusion, failure of the cavern seal, failure of the cavern through cracks, failure of the cavern through leaky interbeds, and a partial collapse of the cavern roof. Assuming a single, generic, salt cavern and generic oil-field wastes, potential human health effects associated with constituent hazardous substances (arsenic, benzene, cadmium, and chromium) were assessed under each of these scenarios. Preliminary results provided excess cancer risk and hazard index (referring to noncancer health effects) estimates that were well within the US Environmental Protection Agency (EPA) target range for acceptable exposure risk levels. These results led to the preliminary conclusion that from a human health perspective, salt caverns can provide an acceptable disposal method for nonhazardous oil-field wastes

  14. Analysis of cavern and well stability at the West Hackberry SPR site using a full-dome model.

    Energy Technology Data Exchange (ETDEWEB)

    Sobolik, Steven R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve (SPR) West Hackberry site. The cavern field comprises 22 caverns. Five caverns (6, 7, 8, 9, 11) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 17 caverns (101-117) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a three-dimensional geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios corresponding to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant results in this report are relevant to Cavern 6. The cavern is shaped like a bowl with a large ceiling span and is in close proximity to Cavern 9. The analyses predict tensile stresses at the edge of the ceiling during repressurization of Cavern 6 following workover conditions. During a workover the cavern is at low pressure to service a well. The wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension around the edge of the large ceiling span. With time, these stresses relax to a compressive state because of salt creep. However, the potential for salt fracture and propagation exists, particularly towards Cavern 9. With only 200 feet of salt between the caverns, the operational consequences must be examined if the two caverns become connected. A critical time may be during a workover of Cavern 9 in part because of the operational vulnerabilities, but also because dilatant damage

  15. [Cavernous hemangiomas of the skin of the face and neck and the oral soft tissues].

    Science.gov (United States)

    Chumakova, M A; Chumakova, T G; Chumakov, A A

    2007-01-01

    The structure, clinical manifestations, behavior of cavernous hemangomas of the skin of the face and neck, and the oral soft tissues were studied, by using biopsy specimens from 229 patients. Three types of cavernous hemagiomas of these areas were identified. Their preferred treatments were defined and pathogenetically warranted. PMID:18074821

  16. Risk assessment of nonhazardous oil-field waste disposal in salt caverns.

    Energy Technology Data Exchange (ETDEWEB)

    Elcock, D.

    1998-03-10

    Salt caverns can be formed in underground salt formations incidentally as a result of mining or intentionally to create underground chambers for product storage or waste disposal. For more than 50 years, salt caverns have been used to store hydrocarbon products. Recently, concerns over the costs and environmental effects of land disposal and incineration have sparked interest in using salt caverns for waste disposal. Countries using or considering using salt caverns for waste disposal include Canada (oil-production wastes), Mexico (purged sulfates from salt evaporators), Germany (contaminated soils and ashes), the United Kingdom (organic residues), and the Netherlands (brine purification wastes). In the US, industry and the regulatory community are pursuing the use of salt caverns for disposal of oil-field wastes. In 1988, the US Environmental Protection Agency (EPA) issued a regulatory determination exempting wastes generated during oil and gas exploration and production (oil-field wastes) from federal hazardous waste regulations--even though such wastes may contain hazardous constituents. At the same time, EPA urged states to tighten their oil-field waste management regulations. The resulting restrictions have generated industry interest in the use of salt caverns for potentially economical and environmentally safe oil-field waste disposal. Before the practice can be implemented commercially, however, regulators need assurance that disposing of oil-field wastes in salt caverns is technically and legally feasible and that potential health effects associated with the practice are acceptable. In 1996, Argonne National Laboratory (ANL) conducted a preliminary technical and legal evaluation of disposing of nonhazardous oil-field wastes (NOW) into salt caverns. It investigated regulatory issues; the types of oil-field wastes suitable for cavern disposal; cavern design and location considerations; and disposal operations, closure and remediation issues. It determined

  17. Risk assessment of nonhazardous oil-field waste disposal in salt caverns

    International Nuclear Information System (INIS)

    Salt caverns can be formed in underground salt formations incidentally as a result of mining or intentionally to create underground chambers for product storage or waste disposal. For more than 50 years, salt caverns have been used to store hydrocarbon products. Recently, concerns over the costs and environmental effects of land disposal and incineration have sparked interest in using salt caverns for waste disposal. Countries using or considering using salt caverns for waste disposal include Canada (oil-production wastes), Mexico (purged sulfates from salt evaporators), Germany (contaminated soils and ashes), the United Kingdom (organic residues), and the Netherlands (brine purification wastes). In the US, industry and the regulatory community are pursuing the use of salt caverns for disposal of oil-field wastes. In 1988, the US Environmental Protection Agency (EPA) issued a regulatory determination exempting wastes generated during oil and gas exploration and production (oil-field wastes) from federal hazardous waste regulations--even though such wastes may contain hazardous constituents. At the same time, EPA urged states to tighten their oil-field waste management regulations. The resulting restrictions have generated industry interest in the use of salt caverns for potentially economical and environmentally safe oil-field waste disposal. Before the practice can be implemented commercially, however, regulators need assurance that disposing of oil-field wastes in salt caverns is technically and legally feasible and that potential health effects associated with the practice are acceptable. In 1996, Argonne National Laboratory (ANL) conducted a preliminary technical and legal evaluation of disposing of nonhazardous oil-field wastes (NOW) into salt caverns. It investigated regulatory issues; the types of oil-field wastes suitable for cavern disposal; cavern design and location considerations; and disposal operations, closure and remediation issues. It determined

  18. Fibrosis of corpus cavernosum in animals following cavernous nerve ablation

    Institute of Scientific and Technical Information of China (English)

    Wan-LiHu; Li-QuanHu; jianSong; Shi-WenLi; Xin-MinZheng; BeiCheng; Bing-ChunTian

    2004-01-01

    t Aim: To investigate alterations of smooth muscle cells and collagen fibers in corpus cavernosum following cavernous neurectomy and its relation to the expression of transforming growth factor-β1 (TGF-β1). Methods: Ten adult male SD rats (neurectomy group) were subject to a bilateral cavernous nerve (CN) resection aseptically under an operating microscope, with 6 sham-operated rats as the control. Fifteen weeks after the operation, the penile specimens were collected and prepared for quantitative-analyzing of ratio of smooth muscle to collagen fibers in corpus cavernosum with confocal microscopy, and for detecting the expression of TGF-β1 by RT-PCR and westernblot.Results: Smooth muscle cells that show red color after fluorescent-labeling with tetramethylrhodamine isothiocyanatephalloidin and collagen fibers that produce green autofluorescence after paraformaldehyde fixation were clearly identified under the confocal microscope. Quantification of fluorescent intensity showed that the ratio of smooth muscle to collagen fibers in corpus cavernosum in neurectomy group was 0.265± 0.125, which was significantly lower than that in sham-operated group (0.760±0.196, P<0.01). RT-PCR and western-blot analyses revealed a significantlyhigher expression of TGF-β1 in the penile tissues of the neurectomy animals than that in sham-operated group.Conclusion: Bilateral ablation of CN can lead to fibrosis of corpus cavernosum, which may be related to an increased expression of TGF-β1 induced by hypoxia in cavernous tissue after denervation.

  19. Worsening angle closure glaucoma and choroidal detachments subsequent to closure of a carotid cavernous fistula

    Directory of Open Access Journals (Sweden)

    Thinda Sumeer

    2012-07-01

    Full Text Available Abstract Background Carotid cavernous fistulas are abnormal communications between the cavernous sinus and the external or internal carotid arteries. Although rare, closure of carotid cavernous fistulas can lead to immediate ocular complications. To our knowledge, our case represents the first report of worsening angle closure glaucoma and choroidal detachments over an extended period of two months subsequent to closure of a carotid cavernous fistula. Case presentation A 70-year-old female with a history of primary angle closure glaucoma presented with 4 mm of proptosis, resistance to retropulsion, tortuous corkscrew blood vessels and an orbital bruit of the right eye. Diagnostic cerebral angiogram showed a small indirect Barrow type D right carotid cavernous fistula. Transarterial embolization was planned but repeat cerebral angiography prior to the procedure demonstrated spontaneous partial closure of the carotid cavernous fistula and the procedure was aborted. One month later, our patient was noted to have worsening vision and choroidal detachments of the right eye. She declined further testing and was thus started on self-administered manual carotid jugular compressions. One month later, she developed progressive worsening of her choroidal detachments and angle closure. She eventually opted for surgical intervention but repeat cerebral angiography showed significant thrombosis of the carotid cavernous fistula and no intervention was warranted. Examination two months later showed complete resolution of the choroidal detachments and open angles of both eyes. Conclusions Our patient demonstrated worsening angle closure glaucoma and choroidal detachments after spontaneous closure of her carotid cavernous fistula had been noted. Ocular complications, including acute angle closure, have been reported to occur immediately after closure of carotid cavernous fistulas, but not over months as in our patient. It is imperative that individuals who have

  20. Atypical Presentation of Cavernous Sinus Infection with Intracavernous ICA Aneurysm

    OpenAIRE

    Pant, Bhawana; Joshi, H. C. K.; Isser, D. K.

    2012-01-01

    In a typical presentation of intracavernous internal carotid artery aneurysm and cavernous sinus infection there is involvement of 3rd, 4th and 6th cranial nerves along with 2nd and 5th cranial nerve. Here we present a case of a 32 years old male with unilateral mycotic intracavernous internal carotid artery aneurysm with a history of head injury. Atypical features in this case was involvement of distantly situated multiple cranial nerves and sparing the 5th cranial nerve and optic nerve whic...

  1. Cavernous Angioma of the Corpus Callosum Presenting with Acute Psychosis

    Directory of Open Access Journals (Sweden)

    Giacomo Pavesi

    2014-01-01

    Full Text Available Psychiatric symptoms may occasionally be related to anatomic alterations of brain structures. Particularly, corpus callosum lesions seem to play a role in the change of patients’ behavior. We present a case of a sudden psychotic attack presumably due to a hemorrhagic cavernous angioma of the corpus callosum, which was surgically removed with complete resolution of symptoms. Although a developmental defect like agenesis or lipoma is present in the majority of these cases, a growing lesion of the corpus callosum can rarely be the primary cause. Since it is potentially possible to cure these patients, clinicians should be aware of this association.

  2. The anterior interhemispheric approach to a third ventricular cavernous malformation.

    Science.gov (United States)

    Martirosyan, Nikolay L; Kalani, M Yashar S; Nakaji, Peter; Spetzler, Robert F

    2016-01-01

    The anterior interhemispheric approach is a workhorse for treatment of lesions in the third ventricle. In this case, we demonstrate the utility of this approach for resecting a complex third ventricular cavernous malformation. We discuss patient positioning, optimal location of the craniotomy, and surgical resection techniques for safe removal of these lesions. We also demonstrate the importance of gravity retraction using the falx to prevent injury to the dominant frontal lobe. The video can be found here: https://youtu.be/38woc28er7M . PMID:26722693

  3. Gamma Knife radiosurgery for the treatment of cavernous sinus hemangiomas

    OpenAIRE

    Xu, Qingsheng; Shen, Jian; Feng, Yiping; ZHAN, Renya

    2015-01-01

    The present retrospective study aimed to analyze the outcome of patients with cavernous sinus hemangioma (CSH) treated with Gamma Knife radiosurgery (GKS). Between August 2011 and April 2014, 7 patients with CSHs underwent GKS. GKS was performed as the sole treatment option in 5 patients, whilst partial resection had been performed previously in 1 patient and biopsy had been performed in 1 patient. The mean volume of the tumors at the time of GKS was 12.5±10.2 cm3 (range, 5.3–33.2 cm3), and t...

  4. Is cerebral cavernous malformation a pre-glioma lesion?

    Institute of Scientific and Technical Information of China (English)

    ZHANG Ji-yang; MING Zong-yi; WU An-hua

    2012-01-01

    Glioma is the most malignant tumor in the brain,the origin of glioma is still unknown.Recently some papers indicated that glioma may be developed from cerebral cavernous malformation (CCM).We describe a man with a right temporal lobe CCM,after gamma-knife radiotherapy,the patient developed a low-grade astrocytoma in the area of the preexistent CCM.This case,together with other reports,may indicated an oncogenetic properties of CCM,and we proposed that CCM may be a pre-glioma lesion.

  5. Nitrogen Monitoring of West Hackberry 117 Cavern Wells.

    Energy Technology Data Exchange (ETDEWEB)

    Bettin, Giorgia; Lord, David

    2015-02-01

    U.S. Strategic Petroleum Reserve (SPR) oil storage cavern West Hackberry 117 was tested under extended nitrogen monitoring following a successful mechanical integrity test in order to validate a newly developed hydrostatic column model to be used to differentiate between normal "tight" well behavior and small-leak behavior under nitrogen. High resolution wireline pressure and temperature data were collected during the test period and used in conjunction with the hydrostatic column model to predict the nitrogen/oil interface and the pressure along the entire fluid column from the bradenhead flange nominally at ground surface to bottom of brine pool. Results here and for other SPR caverns have shown that wells under long term nitrogen monitoring do not necessarily pressurize with a relative rate (P N2 /P brine) of 1. The theoretical relative pressure rate depends on the well configuration, pressure and the location of the nitrogen-oil interface and varies from well to well. For the case of WH117 the predicted rates were 0.73 for well A and 0.92 for well B. The measured relative pressurization rate for well B was consistent with the model prediction, while well A rate was found to be between 0.58-0.68. A number of possible reasons for the discrepancy between the model and measured rates of well A are possible. These include modeling inaccuracy, measurement inaccuracy or the possibility of the presence of a very small leak (below the latest calculated minimum detectable leak rate).

  6. Intraosseous cystic cavernous angioma with occipital skull osteolysis

    Directory of Open Access Journals (Sweden)

    Sakyo Hirai, MD

    2014-09-01

    Full Text Available Intraosseous cavernous angiomas (CAs of the skull are rare, and those cases that appear are commonly localized in the frontal bone. Computed tomography (CT and Magnetic resonance imaging (MRI typically show a well-defined intradiploic lytic mass with homogeneous enhancement. We describe an intraosseous cystic CA of the occipital skull in a 46-year-old man who presented with transient right-sided deafness and posterior cervical pain. MRI revealed a large (3.7 cm × 3.2 cm × 4.1 cm extra-axial tumor, compressing the right cerebellar hemisphere, with heterogeneous peripheral enhancement. A CT scan showed osteolytic change of the occipital skull. The tumor was totally resected via a suboccipital approach. Intraoperatively, we found a mainly cystic tumor containing xanthochromic fluid. Histologically, the tumor was diagnosed as a cavernous angioma. This is the first reported case of an intraosseous CA of the skull with cyst formation. The characteristic radiological imaging of the presented case mimicked a malignant tumor with peripheral enhancement and prominent osteolytic change.

  7. Ultrasonography guided percutaneous radiofrequency ablation for hepatic cavernous hemangioma

    Institute of Scientific and Technical Information of China (English)

    Yan Cui; Hong-Wen Zhang; Li-Yan Zhou; Man-Ku Dong; Ping Wang; Min Ji; Xiao-Ou Li; Chang-Wei Chen; Zi-Pei Liu; Yong-Jie Xu

    2003-01-01

    AIM: Hepatic cavernous hemangioma (HCH) is the mostcommon benign tumor of the liver and its management isstill controversial. Recent successin situ radiofrequencyablation of hepatic malignancies has led us to consider usingthis technique in patients with HCH. This study was to assessthe efficacy, safety, and complications of percutaneousradiofrequency ablation (PRFA) under ultrasonographyguidance in patients with HCH.METHODS: Twelve patients (four men and eight women,age ranged 33-56 years, mean age was 41.7 years) with 15hepatic cavernous hemangiomas (2.5 cm to 9.5 cm) weretreated using the RF-2000 generator and 10-needle LeVeenelectrode percutaneously guided by B-ultrasound. Lesionslarger than 3 cm were treated by multiple overlappingablations that encompass the entire lesion as well as a rimof normal liver tissue (approximately 0.5 cm).RESULTS: All the patients who received PRFA therapy hadno severe pain, bleeding or bile leakage during and afterthe procedures. Nine to 34 months′ follow-up (mean, 21months) by ultrasound and/or spiral CT scan demonstratedthat the ablated lesions in this group were shrunk remarkably,and the shrunken range was 38-79 % (mean, 67 % per 21months). The contrast enhancement was disappeared withinthe tumor or at its periphery in all cases on spiral CT scansobtained 3 to 6 months after treatment.CONCLUSION: The results of this study suggest that PRFAtherapy is a mini-invasive, simple, safe, and effective methodfor the treatment of selected patients with HCH.

  8. Cavernous hemangioma in the thymus: a case report.

    Science.gov (United States)

    Ose, Naoko; Kobori, Yuko; Takeuchi, Yukiyasu; Susaki, Yoshiyuki; Taniguchi, Seiji; Maeda, Hajime

    2016-12-01

    Cavernous hemangioma is not a neoplasm, but rather a congenital venous malformation with the potential to develop in all parts of the body, though it is very rarely seen in the thymus. We report a case of cavernous hemangioma in the thymus partially resected. A 71-year-old woman presented with pericardial discomfort, and chest computed tomography (CT) showed a left lateral mediastinal mass which was 2.0 × 1.2 × 1.8 cm in size, with border regularity and without calcification. Its interior was partially enhanced. Three-dimensional chest computed tomography image showed a tortuous vessel connecting to the tumor. Surgical resection was performed for the purpose of providing a definitive diagnosis and treatment because a mediastinal tumor such as thymoma or teratoma was suspected. Partial resection of the thymus including the mass was done by utilizing a three-port, left-sided video-assisted thoracic surgery (VATS) approach with hoisting of the third rib with the patient in a spinal position. A wine-colored mass bulging from the surface of the left lobe of the thymus was identified along with the communicating vessel which could only be cut with an energy device. It is considered that thymic partial resection using VATS is a better option for small and non-infiltrative lesions. PMID:26943686

  9. Cerebral cavernous malformations: from genes to proteins to disease.

    Science.gov (United States)

    Cavalcanti, Daniel D; Kalani, M Yashar S; Martirosyan, Nikolay L; Eales, Justin; Spetzler, Robert F; Preul, Mark C

    2012-01-01

    Over the past half century molecular biology has led to great advances in our understanding of angio- and vasculogenesis and in the treatment of malformations resulting from these processes gone awry. Given their sporadic and familial distribution, their developmental and pathological link to capillary telangiectasias, and their observed chromosomal abnormalities, cerebral cavernous malformations (CCMs) are regarded as akin to cancerous growths. Although the exact pathological mechanisms involved in the formation of CCMs are still not well understood, the identification of 3 genetic loci has begun to shed light on key developmental pathways involved in CCM pathogenesis. Cavernous malformations can occur sporadically or in an autosomal dominant fashion. Familial forms of CCMs have been attributed to mutations at 3 different loci implicated in regulating important processes such as proliferation and differentiation of angiogenic precursors and members of the apoptotic machinery. These processes are important for the generation, maintenance, and pruning of every vessel in the body. In this review the authors highlight the latest discoveries pertaining to the molecular genetics of CCMs, highlighting potential new therapeutic targets for the treatment of these lesions. PMID:21962164

  10. A NOVEL PROCESS TO USE SALT CAVERNS TO RECEIVE SHIP BORNE LNG

    Energy Technology Data Exchange (ETDEWEB)

    Michael M. McCall; William M. Bishop; Marcus Krekel; James F. Davis; D. Braxton Scherz

    2005-05-31

    This cooperative research project validates use of man made salt caverns to receive and store the cargoes of LNG ships in lieu of large liquid LNG tanks. Salt caverns will not tolerate direct injection of LNG because it is a cryogenic liquid, too cold for contact with salt. This research confirmed the technical processes and the economic benefits of pressuring the LNG up to dense phase, warming it to salt compatible temperatures and then directly injecting the dense phase gas into salt caverns for storage. The use of salt caverns to store natural gas sourced from LNG imports, particularly when located offshore, provides a highly secure, large scale and lower cost import facility as an alternative to tank based LNG import terminals. This design can unload a ship in the same time as unloading at a tank based terminal. The Strategic Petroleum Reserve uses man made salt caverns to securely store large quantities of crude oil. Similarly, this project describes a novel application of salt cavern gas storage technologies used for the first time in conjunction with LNG receiving. The energy industry uses man made salt caverns to store an array of gases and liquids but has never used man made salt caverns directly in the importation of LNG. This project has adapted and expanded the field of salt cavern storage technology and combined it with novel equipment and processes to accommodate LNG importation. The salt cavern based LNG receiving terminal described in the project can be located onshore or offshore, but the focus of the design and cost estimates has been on an offshore location, away from congested channels and ports. The salt cavern based terminal can provide large volumes of gas storage, high deliverability from storage, and is simplified in operation compared to tank based LNG terminals. Phase I of this project included mathematical modeling that proved a salt cavern based receiving terminal could be built at lower capital cost, and would have significantly higher

  11. Literature Survey Concerning the Feasibility of Remedial Leach for Select Phase I Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Paula D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Flores, Karen A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lord, David L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    Bryan Mound 5 ( BM5 ) and West Hackberry 9 ( WH9 ) have the potential to create a significant amount of new storage space should the caverns be deemed "leach - ready". This study discusses the original drilling history of the caverns, surrounding geology, current stability, and, based on this culmination of data, makes a preliminary assessment of the leach potential for the cavern. The risks associated with leaching BM5 present substantial problems for the SPR . The odd shape and large amount of insoluble material make it difficult to de termine whether a targeted leach would have the desired effect and create useable ullage or further distort the shape with preferential leaching . T he likelihood of salt falls and damaged or severed casing string is significant . In addition, a targeted le ach would require the relocation of approximately 27 MMB of oil . Due to the abundance of unknown factors associated with this cavern, a targeted leach of BM5 is not recommended. A targeted leaching of the neck of WH 9 could potentially eliminate or diminis h the mid - cavern ledge result ing in a more stable cavern with a more favorable shape. A better understanding of the composition of the surrounding salt and a less complicated leaching history yields more confidence in the ability to successfully leach this region. A targeted leach of WH9 can be recommended upon the completion of a full leach plan with consideration of the impacts upon nearby caverns .

  12. [Plea for a unifying concept of the cavernous sinus and the trigeminal cavity].

    Science.gov (United States)

    Bataille, B; Sakka, M; Lapierre, F

    The object of this study is a scientific research in human and compared anatomy of the cavernous sinus and Meckel's cave. The observations made in the foetus and human adult are compared to these made in non human primates and domestic mammals, the cavernous sinus and the Meckel's cave contribute to realize a entirety that we call "a morphological and functional anatomical system". The human cavernous sinus and Meckel's cave are described as an indissociable parasellar space representing a heavy traffic area for vascular and nervous structures. In the human and non human primates, the authors observe a parasellar space which agreed with the concept of "trigeminal-cavernous anatomical system". In the cat, the same observations are made and an osseous outline closing the roof of the parasellar space is observed; this is the evidence of a more ancient osseous or cartilaginous wall. The authors demonstrate in the last part of this study that the morphogenesis of this trigeminal-cavernous system is in relation with the phylogenic development of its morphological and functional environment, that we call the "externation". This study is of interest: to a best understanding of the tumors involving the cavernous sinus, to a semantic point of view: an attempt to a review of the terminology applied to the cavernous sinus and Meckel's cave. PMID:7729219

  13. CNS Cavernous Hemangioma; Imaging, Clinical Presentation and Related Anatomophysiology

    Directory of Open Access Journals (Sweden)

    Jalal Jalal Shokouhi

    2009-01-01

    Full Text Available "nClinical and imaging judgement or decision: "n- Is it a CH “CM, CA“? "n- Is it solitary, multiple or familial? "n- Is there an associated venous malformation? "n- Are there risks and consequences of hemorrhage? "n- Is the anatomic location critical and life threatening? "nCavernous malformation is a low pressure, slow flowing malformation and composes 10 – 15 % of vascular malformations. Cavernous angioma consists of enlarged sinusoidal vascular spaces, a compact mass in the brain and spinal cord, the endothelial lining is weak and blood element leakage is frequent.Calcification is possible "X – ray CT ". 75% located in the brain and 25 % in the posterior fossa and brain stem. "nAll 50% of cases are multiple and this form is familial in 80 % of cases “possibility combined with cord cavernoma“. "nExtra – medullary and extra – paranchymal forms are rare. "n- 40-60 % of the patients demonstrate seizure because of hemorrhage inside the cavernoma. "n10 – 15 % of complicated patients show significant clinical signs especially in the brain stem."n Imaging: "n1- X-ray CT: Isodense or hyperdense with frequent and heavy calcification . "nEnhanced CT may show the degree of enhancement. "n2 – By MRI: T1 may be isointense but in case of hemorrhage there is bright methemoglobin inside. By T2 and flair a thin capsule and a rim of hemosiderin – ferritin "popcorn or mulberries" and shows enhancement "GD-GRE-MRI pulse". "nCompanion of venous angioma and cavernoma is possible. "nBleeding is more likely from cavernous malformations during pregnancy. "nConclusion: CT and MRI demonstrate all forms and sites of brain and spinal cord cavernomas. "nAttention is necessary for brain stem lesions especially during pregnancy."n Treatment: 1- Medial and serial MRI controls. "n2- Radiosurgery "Gama-knife", rare. "n3- Microsurgery, very rare Multiple forms of these lesions are demonstratable in 55 patients.  

  14. Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment

    Directory of Open Access Journals (Sweden)

    Nikolaos Mouchtouris

    2015-01-01

    Full Text Available Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics.

  15. Observations on vapor pressure in SPR caverns : sources.

    Energy Technology Data Exchange (ETDEWEB)

    Munson, Darrell Eugene

    2010-05-01

    The oil of the Strategic Petroleum Reserve (SPR) represents a national response to any potential emergency or intentional restriction of crude oil supply to this country, and conforms to International Agreements to maintain such a reserve. As assurance this reserve oil will be available in a timely manner should a restriction in supply occur, the oil of the reserve must meet certain transportation criteria. The transportation criteria require that the oil does not evolve dangerous gas, either explosive or toxic, while in the process of transport to, or storage at, the destination facility. This requirement can be a challenge because the stored oil can acquire dissolved gases while in the SPR. There have been a series of reports analyzing in exceptional detail the reasons for the increases, or regains, in gas content; however, there remains some uncertainty in these explanations and an inability to predict why the regains occur. Where the regains are prohibitive and exceed the criteria, the oil must undergo degasification, where excess portions of the volatile gas are removed. There are only two known sources of gas regain, one is the salt dome formation itself which may contain gas inclusions from which gas can be released during oil processing or storage, and the second is increases of the gases release by the volatile components of the crude oil itself during storage, especially if the stored oil undergoes heating or is subject to biological generation processes. In this work, the earlier analyses are reexamined and significant alterations in conclusions are proposed. The alterations are based on how the fluid exchanges of brine and oil uptake gas released from domal salt during solutioning, and thereafter, during further exchanges of fluids. Transparency of the brine/oil interface and the transfer of gas across this interface remains an important unanswered question. The contribution from creep induced damage releasing gas from the salt surrounding the cavern is

  16. Diagnosis and management of trigemino-cavernous fistulas: case reports and review of the literature.

    Science.gov (United States)

    Miller, Timothy R; Jindal, Gaurav; Mohan, Suyash; Fortes, Manuel; Hurst, Robert; Pukenas, Bryan; Gandhi, Dheeraj

    2015-01-01

    Although usually asymptomatic, a persistent trigeminal artery (PTA) can rarely be associated with a direct fistula to the cavernous sinus (ie, trigemino-cavernous fistula). We present three patients with trigemino-cavernous fistulas; two were subsequently treated using modern endovascular techniques while the third initially declined therapy. We then review the literature of reported cases of this unusual entity. The aberrant anatomy associated with a PTA presents unique challenges to the management of these lesions, and must be well delineated prior to treatment. Finally, conservative management of trigemino-cavernous fistulas, either de novo or recurrent, may be considered if they demonstrate no evidence of cortical venous reflux and patient symptoms are tolerable. PMID:24394154

  17. Dural carotid cavernous sinus fistula presenting as isolated oculomotor nerve palsy: Case report

    Directory of Open Access Journals (Sweden)

    Şehnaz Arıcı

    2015-04-01

    Full Text Available Indirect (dural carotid cavernous fistula is formed by the connection between meningeal branches of the internal carotid artery and the cavernous sinüs, and low flow circulation with low pressure is occured. Proptosis, ophtalmoplegia, headache, scleral and conjuctival hyperemia expanding around the eyeball can be observed. A forty-eight year old female patient with a background of diabetes mellitus and hypertension was admitted with complaints of double vision. Isolated oculomotor nerve palsy was found in neurological examination and an indirect carotid cavernous fistula was revealed by digital subtraction angiography. Our case with carotid cavernous fistula as a rare cause of isolated oculomotor nerve palsy is worth to be reported.

  18. Long-term measurements and estimation of time-dependent deformation of large scale underground cavern

    International Nuclear Information System (INIS)

    The time-dependent deformation of rock mass is an important factor to evaluate the soundness of underground caverns and a reliable estimation method of the deformation is needed for the maintenance. Based on long-term measurements, the feature of the time-dependent deformation of the cavern are clarified. As the results, we focus on the compliance variable model proposed by Okubo et al, that can express nonlinear viscoelastic behavior and the over-peak-strength state analytically. Determination methods of parameters of the compliance variable model are proposed and these are utilized to compare with the cavern's real behavior that has been measured for about ten years since the excavation was completed. Finally, the estimation analysis of the underground cavern deformation is conducted and the long-term stability is evaluated. (author)

  19. Transient behaviour of deep underground salt caverns; Comportement transitoire des cavites salines profondes

    Energy Technology Data Exchange (ETDEWEB)

    Karimi-Jafari, M

    2007-11-15

    This work deals with the transient behaviour of deep underground salt caverns. It has been shown that a cavern is a complex system, in which there are mechanical, thermal, chemical and hydraulic evolutions. The importance of the transient evolutions, particularly the role of the 'reverse' creep in the interpretation of the tightness test in a salt cavern is revealed. Creep is characterized by a formulation of the behaviour law which presents the advantage, in a practical point of view, to only have a reduced number of parameters while accounting of the essential of what it is observed. The initiation of the rupture in the effective traction in a salt cavern rapidly pressurized is discussed. A model fitted to a very long term behaviour (after abandonment) is developed too. In this case too, a lot of phenomena, more or less coupled, occur, when the existing literature took only into account some phenomena. (O.M.)

  20. Dural cavernous sinus fistulas. Diagnostic and endovascular therapy

    Energy Technology Data Exchange (ETDEWEB)

    Benndorf, Goetz [Baylor College of Medicine, Houston, TX (United States). Dept. of Radiology; Ben Taub General Hospital, Houston, TX (United States). Interventional Neuroradiology

    2010-07-01

    Dural cavernous sinus fistulas (DCSFs) represent a benign vascular disease, consisting in an arteriovenous shunt at the cavernous sinus. In the absence of spontaneous resolution, the fistula may lead to eye redness, swelling, proptosis, chemosis, ophthalmoplegia and visual loss. Although modern imaging techniques have improved the diagnostic, patients with low-flow DCSFs are still misdiagnosed. These patients can get erroneously treated for infections and inflammation for months or years and are at risk of visual loss. Early and proper diagnosis helps to avoid deleterious clinical course of the disease. This volume provides a complete guide to clinical and radiological diagnosis as well as to therapeutic management of DCSF with emphasis on modern minimal invasive treatment options. It commences with an informative description of relevant anatomy. After sections on the classification, etiology and pathogenesis of DCSF, the clinical symptomatology of the disease is described in detail. The role of modern non-invasive imaging tools is then addressed with the use of computed tomography, magnetic resonance imaging and ultrasound. Intra-arterial digital subtraction angiography (DSA), although invasive, remains the gold standard and is mandatory for clinical decision-making and strategy in endovascular treatment. Hence, a throughout consideration is given to both, 2D-DSA and 3D rotational angiography, including recent technological advancements such as Dual Volume (DV) imaging and angiographic computed tomography (ACT). After a short section on arteriovenous hemodynamics, the therapeutic management of DCSFs is described in detail. In particular, various transvenous techniques, required for successful endovascular occlusion of DCSF, are discussed in depth. This well-illustrated volume will be invaluable to all who may encounter DCSF in their clinical practice. (orig.)

  1. Numerical evaluation of the groundwater drainage system for underground storage caverns

    Science.gov (United States)

    Park, Eui Seob; Chae, Byung Gon

    2015-04-01

    A novel concept storing cryogenic liquefied natural gas in a hard rock lined cavern has been developed and tested for several years as an alternative. In this concept, groundwater in rock mass around cavern has to be fully drained until the early stage of construction and operation to avoid possible adverse effect of groundwater near cavern. And then rock mass should be re-saturated to form an ice ring, which is the zone around cavern including ice instead of water in several joints within the frozen rock mass. The drainage system is composed of the drainage tunnel excavated beneath the cavern and drain holes drilled on rock surface of the drainage tunnel. In order to de-saturate sufficiently rock mass around the cavern, the position and horizontal spacing of drain holes should be designed efficiently. In this paper, a series of numerical study results related to the drainage system of the full-scale cavern are presented. The rock type in the study area consists mainly of banded gneiss and mica schist. Gneiss is in slightly weathered state and contains a little joint and fractures. Schist contains several well-developed schistosities that mainly stand vertically, so that vertical joints are better developed than the horizontals in the area. Lugeon tests revealed that upper aquifer and bedrock are divided in the depth of 40-50m under the surface. Groundwater level was observed in twenty monitoring wells and interpolated in the whole area. Numerical study using Visual Modflow and Seep/W has been performed to evaluate the efficiency of drainage system for underground liquefied natural gas storage cavern in two hypothetically designed layouts and determine the design parameters. In Modflow analysis, groundwater flow change in an unconfined aquifer was simulated during excavation of cavern and operation of drainage system. In Seep/W analysis, amount of seepage and drainage was also estimated in a representative vertical section of each cavern. From the results

  2. EXAMINE AND EVALUATE A PROCESS TO USE SALT CAVERNS TO RECEIVE SHIP BORNE LIQUEFIED NATURAL GAS

    Energy Technology Data Exchange (ETDEWEB)

    Michael M. McCall; William M. Bishop; D. Braxton Scherz

    2003-04-24

    The goal of the U.S. Department of Energy cooperative research project is to define, describe, and validate, a process to utilize salt caverns to receive and store the cargoes of LNG ships. The project defines the process as receiving LNG from a ship, pumping the LNG up to cavern injection pressures, warming it to cavern compatible temperatures, injecting the warmed vapor directly into salt caverns for storage, and distribution to the pipeline network. The performance of work under this agreement is based on U.S. Patent 5,511,905, and other U.S. and Foreign pending patent applications. The cost sharing participants in the research are The National Energy Technology Laboratory (U.S. Department of Energy), BP America Production Company, Bluewater Offshore Production Systems (U.S.A.), Inc., and HNG Storage, L.P. Initial results indicate that a salt cavern based receiving terminal could be built at about half the capital cost, less than half the operating costs and would have significantly higher delivery capacity, shorter construction time, and be much more secure than a conventional liquid tank based terminal. There is a significant body of knowledge and practice concerning natural gas storage in salt caverns, and there is a considerable body of knowledge and practice in handling LNG, but there has never been any attempt to develop a process whereby the two technologies can be combined. Salt cavern storage is infinitely more secure than surface storage tanks, far less susceptible to accidents or terrorist acts, and much more acceptable to the community. The project team developed conceptual designs of two salt cavern based LNG terminals, one with caverns located in Calcasieu Parish Louisiana, and the second in Vermilion block 179 about 50 miles offshore Louisiana. These conceptual designs were compared to conventional tank based LNG terminals and demonstrate superior security, economy and capacity. The potential for the development of LNG receiving terminals

  3. Traumatic Persistent Trigeminal Artery - Cavernous Sinus Fistula Treated by Transcatheter Arterial Embolization

    Science.gov (United States)

    Asai, K.; Hasuo, K.; Hara, T.; Miyagishima, T.; Terano, N.

    2010-01-01

    Summary We describe a rare case of traumatic persistent trigeminal artery (PTA) - cavernous sinus fistula. Cerebral angiography showed direct communication between the right PTA and the cavernous sinus which was treated by transcathether arterial embolization. Although previous reports have indicated the use of more coils to treat this condition, we successfully treated the patient with only two coils placed near the orifice of the fistula after sufficient anatomical evaluation. PMID:20377986

  4. Traumatic persistent trigeminal artery--cavernous sinus fistula treated by transcatheter arterial embolization. A case report.

    Science.gov (United States)

    Asai, K; Hasuo, K; Hara, T; Miyagishima, T; Terano, N

    2010-03-01

    We describe a rare case of traumatic persistent trigeminal artery (PTA) - cavernous sinus fistula. Cerebral angiography showed direct communication between the right PTA and the cavernous sinus which was treated by transcathether arterial embolization. Although previous reports have indicated the use of more coils to treat this condition, we successfully treated the patient with only two coils placed near the orifice of the fistula after sufficient anatomical evaluation. PMID:20377986

  5. Traumatic Persistent Trigeminal Artery - Cavernous Sinus Fistula Treated by Transcatheter Arterial Embolization: A Case Report

    OpenAIRE

    Asai, K.; Hasuo, K; Hara, T.; Miyagishima, T.; Terano, N.

    2010-01-01

    We describe a rare case of traumatic persistent trigeminal artery (PTA) - cavernous sinus fistula. Cerebral angiography showed direct communication between the right PTA and the cavernous sinus which was treated by transcathether arterial embolization. Although previous reports have indicated the use of more coils to treat this condition, we successfully treated the patient with only two coils placed near the orifice of the fistula after sufficient anatomical evaluation.

  6. Spontaneous occlusion of traumatic carotid-cavernous fistula - the effect of angiography

    International Nuclear Information System (INIS)

    In two patients with a traumatic carotid-cavernous fistula, permanent occlusion of the lesion was observed following cerebral angiography and confirmed by further angiography. A delay is therefore recommended between performing angiography and carrying out further treatment, which may carry some risk. Possibly the use of ionic contrast media, which irritate the vessels, compression of the carotid artery, which reduces flow through the fistula, and general anaesthesia, which may drop the blood pressure, initiate thrombosis in the cavernous sinus. (orig.)

  7. Diagnosis of orbital cavernous hemangioma with Tc-99m RBC SPECT.

    Science.gov (United States)

    Ki, W W; Shin, J W; Won, K S; Ryu, J S; Yang, S O; Lee, H K; Kim, Y J

    1997-08-01

    The authors report two cases of orbital cavernous hemangioma diagnosed by Tc-99m RBC SPECT. Tc-99m RBC SPECT showed a typical scintigraphic pattern commonly seen in hepatic hemangioma in which there is intense focally increased uptake on delayed SPECT images. Tc-99m RBC SPECT in orbital cavernous hemangioma may be as useful a diagnostic modality as in hepatic hemangioma. PMID:9262901

  8. Light and scanning electron microscopical study of the cavernous sinus of the monkey, Macaca fascicularis.

    OpenAIRE

    Rajendran, K.; Ling, E A

    1985-01-01

    The cavernous sinus of Macaca fascicularis is in many respects similar to the human sinus. It consists predominantly of one main venous channel that, together with the internal carotid artery, occupies a meningo-endocranial compartment lateral to the pituitary gland. Trabeculae are few and do not in any way cause the sinus to appear cavernous. They are mostly flattened in the direction of the main venous channel. Cranial nerves three, four, six and the ophthalmic division of five are all loca...

  9. The CMS cavern at Point 5 (SX5) in February 2005

    CERN Multimedia

    Tejinder S. Virdee

    2005-01-01

    The CMS cavern at Point 5 (also called SX5) in Cessy, neighbouring France. The 4th and 5th pictures, taken in March 2003, shows the cavern during its construction, while the first three photos are taken once ready in February 2005. Fig. 6 shows the structure assembly in June 2005 and Fig. 7 the civil engineering works on the SX5 surface in April 2004.

  10. TIPS Placement via Combined Transjugular and Transhepatic Approach for Cavernous Portal Vein Occlusion: Targeted Approach

    OpenAIRE

    Natanel Jourabchi; Justin Pryce McWilliams; Edward Wolfgang Lee; Steven Sauk; Stephen Thomas Kee

    2013-01-01

    Purpose. We report a novel technique which aided recanalization of an occluded portal vein for transjugular intrahepatic portosystemic shunt (TIPS) creation in a patient with symptomatic portal vein thrombosis with cavernous transformation. Some have previously considered cavernous transformation a contraindication to TIPS. Case Presentation. 62-year-old man with chronic pancreatitis, portal vein thrombosis, portal hypertension and recurrent variceal bleeding presents with melena and hemateme...

  11. Disposal of NORM-Contaminated Oil Field Wastes in Salt Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Blunt, D.L.; Elcock, D.; Smith, K.P.; Tomasko, D.; Viel, J.A.; and Williams, G.P.

    1999-01-21

    In 1995, the U.S. Department of Energy (DOE), Office of Fossil Energy, asked Argonne National Laboratory (Argonne) to conduct a preliminary technical and legal evaluation of disposing of nonhazardous oil field waste (NOW) into salt caverns. That study concluded that disposal of NOW into salt caverns is feasible and legal. If caverns are sited and designed well, operated carefully, closed properly, and monitored routinely, they can be a suitable means of disposing of NOW (Veil et al. 1996). Considering these findings and the increased U.S. interest in using salt caverns for NOW disposal, the Office of Fossil Energy asked Argonne to conduct further research on the cost of cavern disposal compared with the cost of more traditional NOW disposal methods and on preliminary identification and investigation of the risks associated with such disposal. The cost study (Veil 1997) found that disposal costs at the four permitted disposal caverns in the United States were comparable to or lower than the costs of other disposal facilities in the same geographic area. The risk study (Tomasko et al. 1997) estimated that both cancer and noncancer human health risks from drinking water that had been contaminated by releases of cavern contents were significantly lower than the accepted risk thresholds. Since 1992, DOE has funded Argonne to conduct a series of studies evaluating issues related to management and disposal of oil field wastes contaminated with naturally occurring radioactive material (NORM). Included among these studies were radiological dose assessments of several different NORM disposal options (Smith et al. 1996). In 1997, DOE asked Argonne to conduct additional analyses on waste disposal in salt caverns, except that this time the wastes to be evaluated would be those types of oil field wastes that are contaminated by NORM. This report describes these analyses. Throughout the remainder of this report, the term ''NORM waste'' is used to mean &apos

  12. Acute Cavernous Sinus Syndrome from Metastasis of Lung Cancer to Sphenoid Bone

    OpenAIRE

    Zelenak, Marianna; Doval, Mariana; Gorscak, Jason J.; Cuscela, Daniel O.

    2012-01-01

    Cavernous sinus syndrome is a rare entity in oncology reported only in occasional case reports. Optimal therapy is thus poorly defined with rapidly progressive disease dominating the picture. Management includes prompt diagnosis, attempts at stabilization of cranial nerve function, and aggressive control of central pain syndrome. Here, we report cavernous sinus syndrome secondary to the original squamous cell carcinoma of the lung. With common presenting causes of this syndrome being infectio...

  13. Effect of sildenafil in cavernous arteries of patients with erectile dysfunction

    OpenAIRE

    Joaquim A. Claro; Sérgio F Ximenes; Archimedes Nardozza Jr.; Enrico Andrade; Leonardo Messina; Miguel Srougi

    2003-01-01

    INTRODUCTION: Sildenafil citrate is a type 5 phosphodiesterase inhibitor, which has demonstrated excellent results in the treatment of erectile dysfunction. The effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction has not been established yet. The objective of this study was to assess the effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction, following an intracavernous injection of alprostadil. MATERIALS AND METHO...

  14. A rare case of abnormal uterine bleeding caused by cavernous hemangioma: a case report

    OpenAIRE

    Telesinghe PU; Yaakub Hjh; Benjamin Mridula A; Kafeel Gazala

    2010-01-01

    Abstract Introduction Cavernous hemangiomas of the uterus are extremely rare, benign lesions. A survey of the current literature identified fewer than 50 cases of hemangioma of the uterus. Case presentation We report a case of cavernous hemangioma of the uterus in a 27-year-old Malay, para 1 woman who presented at our hospital with torrential vaginal bleeding having been transferred by land ambulance from a district hospital 30 minutes away. 11 weeks previously she had an urgent cesarean sect...

  15. Evaluation of MR imaging findings differentiating cavernous haemangiomas from schwannomas in the orbit

    Energy Technology Data Exchange (ETDEWEB)

    Xian, Junfang; Zhang, Zhengyu; Wang, Zhenchang; Li, Jing; Yang, Bentao; Chen, Qinghua; Chang, Qinglin; He, Liyan [Capital Medical University, Beijing Tongren Hospital, Department of Radiology, Beijing (China)

    2010-09-15

    It is important to distinguish between orbital cavernous haemangioma and schwannoma because the treatments of choice for the two tumours are different. The aim was to evaluate MR imaging findings distinguishing the two tumours. Magnetic resonance imaging including T1- and T2-weighted imaging and contrast-enhanced MR imaging was performed in 43 patients with cavernous haemangiomas and 16 patients with schwannomas confirmed by pathology. Location, configuration, margins, signal intensity, homogeneity and enhancement pattern of the tumour were retrospectively evaluated. There was a significant difference between cavernous haemangiomas and schwannomas regarding the location, configuration and margins of the mass, signal intensity and homogeneity on T1- and T2-weighted imaging, the spread pattern of contrast enhancement, the enhancement pattern and the type of time-intensity curve (P < 0.05). Markedly homogeneous hyperintensity signal on T2-weighted imaging and the spread pattern of the contrast enhancement favoured cavernous haemangioma rather than schwannoma (P < 0.01). Cavernous haemangiomas and schwannomas have different MR imaging features that could be helpful in the differentiation between the tumours. The spread pattern of the contrast enhancement on dynamic contrast-enhanced MR imaging is the most reliable finding distinguishing cavernous haemangiomas from schwannomas. (orig.)

  16. Deformation and Failure Characteristics of the Rock Masses around Deep Underground Caverns

    Directory of Open Access Journals (Sweden)

    Chong Zhang

    2015-01-01

    Full Text Available The deformation and failure characteristics of deep rock masses are the focus of this study on deep rock mass engineering. The study identifies the deformation and failure characteristics of a deep cavern under different ground stress conditions using model test and theoretical analysis methods. First, the similarity theory for model tests is introduced, and then the scale factors used in the present study are calculated according to the Froude criterion. Based on the study objectives, the details of the study methods (the similarity coefficient, the loading conditions, the test steps, etc. are introduced. Finally, the failure characteristics of the deep cavern and the strain distribution characteristics surrounding the caverns under different ground stress conditions are identified using the model test. It was found that compared with shallow rock masses the rock masses of the deep cavern have a much greater tensile range, which reaches 1.5 times the diameter of the cavern under the conditions established in the present study. Under different ground stress conditions, there are differences in failure characteristics and the reasons of the differences were analyzed. The implication of the test results on the design of support system for deep caverns was presented.

  17. Risk analyses for disposing nonhazardous oil field wastes in salt caverns

    Energy Technology Data Exchange (ETDEWEB)

    Tomasko, D.; Elcock, D.; Veil, J.; Caudle, D.

    1997-12-01

    Salt caverns have been used for several decades to store various hydrocarbon products. In the past few years, four facilities in the US have been permitted to dispose nonhazardous oil field wastes in salt caverns. Several other disposal caverns have been permitted in Canada and Europe. This report evaluates the possibility that adverse human health effects could result from exposure to contaminants released from the caverns in domal salt formations used for nonhazardous oil field waste disposal. The evaluation assumes normal operations but considers the possibility of leaks in cavern seals and cavern walls during the post-closure phase of operation. In this assessment, several steps were followed to identify possible human health risks. At the broadest level, these steps include identifying a reasonable set of contaminants of possible concern, identifying how humans could be exposed to these contaminants, assessing the toxicities of these contaminants, estimating their intakes, and characterizing their associated human health risks. The contaminants of concern for the assessment are benzene, cadmium, arsenic, and chromium. These were selected as being components of oil field waste and having a likelihood to remain in solution for a long enough time to reach a human receptor.

  18. Transvenous embolization of indirect carotid-cavernous fistula via upper ophthalmic/facial vein - Case report and literature review

    International Nuclear Information System (INIS)

    Indirect carotid-cavernous fistula or dural arterio-venous fistula of cavernous sinus is relatively rare pathologic finding. Different classifications of carotid-cavernous fistulae are proposed. Now days more and more they are treated by endovascular approach. A case of authors' practice of transvenous embolization of carotid-cavernous fistula via upper ophthalmic vein in 52 year old female is presented with review of the literature. A week later ocular symptoms of the patient regressed. Control angiography at the third month follow up does not visualize fistula. The transvenous approach in management of carotid cavernous fistulae is safe and effective in cases direct arterial approach is absent or technically impossible. Key words: Indirect Carotid-Cavernous Fistula. Embolization. Transvenous Approach

  19. Targeted compartmental embolization of cavernous sinus dural arteriovenous fistulae using transfemoral medial and lateral facial vein approaches

    Energy Technology Data Exchange (ETDEWEB)

    Agid, R.; Willinsky, R.A.; Haw, C.; Souza, M.P.S.; terBrugge, K.G. [Division of Neuroradiology, Department of Medical Imaging, Toronto Western Hospital, Room 210, 3 Fell Pavilion, 399 Bathurst Street, M5T 2S8, Toronto, Ontario (Canada); Vanek, I.J. [Department of Ophthalmology, Toronto Western Hospital, 399 Bathurst St, M5T 2S8, Toronto, Ontario (Canada)

    2004-02-01

    There are multiple transvenous approaches for treatment of cavernous dural arteriovenous fistulae (DAVF). The choice of a specific route depends on the compartment of the cavernous sinus involved in the fistula and its venous drainage. We used two different facial vein approaches to treat patients with cavernous DAVF draining directly into the anterior compartment of the cavernous sinus and thence to the superior ophthalmic vein. Other transvenous routes to the sinus were not apparent. Embolization was targeted to the involved compartment with preservation of those not embolized. No major post-procedure ophthalmic venous engorgement occurred. We believe that ideal treatment of cavernous DAVF is targeted transvenous coil deposition, which necessitates detailed knowledge of the anatomy of the facial veins and cavernous sinus compartments. (orig.)

  20. Japan's exploration of vertical holes and subsurface caverns on the Moon and Mars

    Science.gov (United States)

    Haruyama, J.; Kawano, I.; Kubota, T.; Yoshida, K.; Kawakatsu, Y.; Kato, H.; Otsuki, M.; Watanabe, K.; Nishibori, T.; Yamamoto, Y.; Iwata, T.; Ishigami, G.; Yamada, T. T.

    2013-12-01

    Recently, gigantic vertical holes exceeding several tens of meters in diameter and depth were discovered on the Moon and Mars. Based on high-resolution image data, lunar holes and some Martian pits (called 'holes' hereafter) are probably skylights of subsurface caverns such as lava tubes or magma chambers. We are starting preparations for exploring the caverns through the vertical holes. The holes and subsurface caverns have high potential as resources for scientific studies. Various important geological and mineralogical processes could be uniquely and effectively observed inside these holes and subsurface caverns. The exposed fresh lava layers on the vertical walls of the lunar and Martian holes would provide information on volcanic eruption histories. The lava layers may also provide information on past magnetic fields of the celestial bodies. The regolith layers may be sandwiched between lava layers and may preserve volatile elements including solar wind protons that could be a clue to understanding past solar activities. Water molecules from solar winds or cometary/meteorite impacts may be stored inside the caverns because of mild temperatures there. The fresh lava materials forming the walls and floors of caverns might trap endogenic volatiles from magma eruptions that will be key materials for revealing the formation and early evolution of the Moon and Mars. Furthermore, the Martian subsurface caverns are highly expected to be life cradles where the temperatures are probably stable and that are free from ultra-violet and other cosmic rays that break chemical bonds, thus avoiding polymerization of molecules. Discovering extraterrestrial life and its varieties is one of our ultimate scientific purposes for exploring the lunar and Martian subsurface caverns. In addition to scientific interests, lunar and Martian subsurface caverns are excellent candidates for future lunar bases. We expect such caverns to have high potential due to stable temperatures; absence

  1. Extradural Total Petrous Apex Resection With Trigeminal Translocation for Improved Exposure of the Posterior Cavernous Sinus and Petroclival Region

    OpenAIRE

    Fukushima, Takanori; Day, J. Diaz; Hirahara, Kazuho

    1996-01-01

    We have analyzed a strategy for improved exposure of the posterior cavernous sinus and petroclival region through an extradural subtemporal approach to be utilized in the removal of neoplastic processes with involvement of the apical petrous bone and posterior cavernous sinus. This surgical approach includes the following elements for improved exposure of the posterior cavernous sinus through the middle fossa corridor: (1) maximal extradural exposure and mobilization of the trigeminal nerve c...

  2. Advanced Underground Gas Storage Concepts: Refrigerated-Mined Cavern Storage, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    none

    1998-09-30

    Over the past 40 years, cavern storage of LPG's, petrochemicals, such as ethylene and propylene, and other petroleum products has increased dramatically. In 1991, the Gas Processors Association (GPA) lists the total U.S. underground storage capacity for LPG's and related products of approximately 519 million barrels (82.5 million cubic meters) in 1,122 separate caverns. Of this total, 70 are hard rock caverns and the remaining 1,052 are caverns in salt deposits. However, along the eastern seaboard of the U.S. and the Pacific northwest, salt deposits are not available and therefore, storage in hard rocks is required. Limited demand and high cost has prevented the construction of hard rock caverns in this country for a number of years. The storage of natural gas in mined caverns may prove technically feasible if the geology of the targeted market area is suitable; and economically feasible if the cost and convenience of service is competitive with alternative available storage methods for peak supply requirements. Competing methods include LNG facilities and remote underground storage combined with pipeline transportation to the area. It is believed that mined cavern storage can provide the advantages of high delivery rates and multiple fill withdrawal cycles in areas where salt cavern storage is not possible. In this research project, PB-KBB merged advanced mining technologies and gas refrigeration techniques to develop conceptual designs and cost estimates to demonstrate the commercialization potential of the storage of refrigerated natural gas in hard rock caverns. DOE has identified five regions, that have not had favorable geological conditions for underground storage development: New England, Mid-Atlantic (NY/NJ), South Atlantic (DL/MD/VA), South Atlantic (NC/SC/GA), and the Pacific Northwest (WA/OR). PB-KBB reviewed published literature and in-house databases of the geology of these regions to determine suitability of hard rock formations for siting

  3. Construction of the bridge in the cavern in the Vrata tunnel (Croatia)

    Science.gov (United States)

    Garasic, Mladen; Sasa Kovacevic, Meho; Juric-Kacunic, Danijela

    2010-05-01

    In the Dinaric karst system in Croatia some 11500 speleological objects have been explored so far, more than 1000 of which were discovered during construction works. Such speleological objects without natural entrance on the terrain surface (which are called "caverns") have been discovered on the construction sites of the highways. Over the past twenty years they have been systematically investigated and treated. A special kind of remediation was conducted in the cavern's large hall of the "Vrata" tunnel on the Zagreb - Rijeka highway. Due to size, shape, cavern's position and hydrogeological parameters (fissured and karstified aquifers) within the karst system it was necessary to design and construct a 58 m bridge over the cavern. In addition, the cavern's vault had to be reinforced and stabilized, as the overburden was very thin. The beam-and -stringer grid with special anchors was used. The cavern's rehabilitation in the "Vrata" tunnel was a unique undertaking, and the bridge (without piers) is the cavern's longest bridge in the world. A speleological object of large dimensions was discovered in the "Vrata"tunnel's right tube on the Rijeka-Zagreb highway. Speleological, geotechnical, engineering geological and hydrogeological investigation works were carried out for the purpose of preservation the speleological object (cavern). On the basis of classification results of rock masses and conducted numerical analyses the support system for the cavern's vault stabilization was selected. The support system's elements include the beam-and-stringer grid constructed on the terrain's surface above the cavern, tendons and geotechnical anchors. To ensure stability of the speleological object, and to conduct the backward numerical analyses the measurement of vertical deformations from the terrain's surface along the rock's mass by means of sliding micrometers was undertaken. Backward numerical analyses combined with geotechnical measurements enable safer and more rational

  4. Treatment Outcome Of Seizures Associated With Intracranial Cavernous Angiomas

    Directory of Open Access Journals (Sweden)

    Nievera Conrad C

    1999-01-01

    Full Text Available Seizures are among the typical presentations of intracranial cavernous angiomas (ICA. Twenty-one patients (age range: 2 to 53 years treated for seizures associated with ICA between 1983 and 1997 were restrospectively studied to evaluate their outcome following medical or surgical intervention. The mean interval between seizure onset and initial presentation at our institution was 7.6 years. Seizures were simple partial in 3 patients, complex partial in 15 and secondarily generalized tonic-clonic in 13. The commonest site of the lesion was the temporal lobe (52%. Multiple angiomas were observed in 5 (24% patients. Seven (32% patients were medically-managed with antiepileptic therapy and 14 (68% underwent either lesionectomy with resection of the epileptogenic zone (9 patients or temporal lobectomy (5 patients. Mean follow-up time was 4 years (range: 3 months to 14 years. Of the medically-managed patients, 3 (43% remained seizure-free whereas 4 (57% continued to have seizures with an average frequency of one per day. Of the surgically-managed patients, 12 (86% became seizure-free and 2 (14% had no more than two seizures per year. Surgery appears to be extremely effective in the management of seizures associated with ICA and should receive a strong and early consideration in patients who fail medical therapy.

  5. Surgical management of cavernous malformations coursing with drug resistant epilepsy

    Directory of Open Access Journals (Sweden)

    Mario Arturo Alonso-Vanegas

    2012-01-01

    Full Text Available Cerebral cavernous malformations (CM are dynamic lesions characterized by continuous size changes and repeated bleeding. When involving cortical tissue, CM pose a significant risk for the development of drug-resistant epilepsy, which is thought to be result of an altered neuronal network caused by the lesion itself and its blood degradation products. Preoperative evaluation should comprise a complete seizure history, neurological examination, epilepsy-oriented MRI, EEG, video-EEG, completed with SPECT, PET, functional MRI and/or invasive monitoring as needed. Radiosurgery shows variable rates of seizure freedom and a high incidence of complications, thus microsurgical resection remains the optimal treatment for CM coursing with drug-resistant epilepsy.Two thirds of patients reach Engel I class at three-year follow-up, regardless of lobar location. Those with secondarily generalized seizures, a higher seizure frequency, and generalized abnormalities on preoperative or postoperative EEG, show poorer outcomes, while factors such as gender, duration of epilepsy, lesion size, age, bleeding at the time of surgery, do not correlate consistently with seizure outcome. Electrocorticography and a meticulous removal of all cortical hemosiderin –beyond pure lesionectomy– reduce the risk of symptomatic recurrences.

  6. Second Barrel Toroid Coil Installed in ATLAS Cavern

    CERN Multimedia

    Tappern, G.

    The second barrel toroid coil was lowered into the ATLAS Cavern on Friday, 26 November. The operation takes approximately five hours of precision crane and winch operations. Before lowering, several checks are made to ensure that no loose items have been left on the coil which would fall during the lowering down the shaft. This is a very difficult, but very important check, with the first coil in position, and partly below the shaft. After changing the winch tooling on Wednesday December 1st, the coil was lifted, rotated and placed into the feet. The girders which support the coil and the Z direction stops had all been pre-set before putting the coil in the feet. The angle is controlled by an inclinometer. When the final adjustments of position have been made, which will locate the coils at the plus/minus two mm level, the connection beams (voussoirs and struts) will be put in place; this requires a complex shimming procedure. This will lock together the two coils into the feet and forms the foundation for th...

  7. Gamma Knife radiosurgery for the treatment of cavernous sinus hemangiomas

    Science.gov (United States)

    XU, QINGSHENG; SHEN, JIAN; FENG, YIPING; ZHAN, RENYA

    2016-01-01

    The present retrospective study aimed to analyze the outcome of patients with cavernous sinus hemangioma (CSH) treated with Gamma Knife radiosurgery (GKS). Between August 2011 and April 2014, 7 patients with CSHs underwent GKS. GKS was performed as the sole treatment option in 5 patients, whilst partial resection had been performed previously in 1 patient and biopsy had been performed in 1 patient. The mean volume of the tumors at the time of GKS was 12.5±10.2 cm3 (range, 5.3–33.2 cm3), and the median prescription of peripheral dose was 14.0 Gy (range, 10.0–15.0 Gy). The mean follow-up period was 20 months (range, 6–40 months). At the last follow-up, the lesion volume had decreased in all patients, and all cranial neuropathies observed prior to GKS had improved. There were no radiation-induced neuropathies or complications during the follow-up period. GKS appears to be an effective and safe treatment modality for the management of CSHs. PMID:26893777

  8. Cavernous sinus invasion by pituitary macroadenomas: neuroradiological, clinical and surgical correlation

    Directory of Open Access Journals (Sweden)

    CUKIERT ARTHUR

    1998-01-01

    Full Text Available The classical imaging gold-standard for this diagnosis is the presence of tumor lateral to the carotid artery. Seventeen patients with pituitary macroadenomas with intraoperative confirmation of cavernous sinus invasion were studied with MRI. Only 8 patients had tumor lateral to the carotid artery; 13 had tumor within the carotid syphon and all lacked the ring enhancement of the medial wall of the cavernous sinus. In 10 patients, widening of the posterior double leaflets of the cavernous sinus could be. All patients were operated by the transesphenoidal route. Only one patient was cured by surgery alone. Only 3 patients disclosing the above mentioned MRI features were identified in a series of 250 patients and did not have cavernous sinus invasion. The present criteria proved to be useful in the pre-operative diagnosis of cavenous sinus invasion and patients' counselling. Pre-operative diagnosis of cavernous sinus invasion of pituitary tumors has a great impact in the management of such patients.

  9. Familial cerebral cavernous haemangioma diagnosed in an infant with a rapidly growing cerebral lesion

    International Nuclear Information System (INIS)

    Cavernous haemangiomas of the central nervous system are vascular malformations best imaged by MRI. They may present at any age, but to our knowledge only 39 cases in the first year of life have previously been reported. A familial form has been described and some of the underlying genetic mutations have recently been discovered. We present the clinical features and serial MRI findings of an 8-week-old boy who presented with subacute intracranial haemorrhage followed by rapid growth of a surgically proven cavernous haemangioma, mimicking a tumour. He also developed new lesions. A strong family history of neurological disease was elucidated. A familial form of cavernous haemangioma was confirmed by identification of a KRIT 1 gene mutation and cavernous haemangiomas in the patient and other family members. We stress the importance of considering cavernous haemangiomas in the context of intracerebral haemorrhage and in the differential diagnosis of rapidly growing lesions in this age group. The family history is also important in screening for familial disease

  10. A study on the structural behaviour of rock caverns for underground radioactive waste repository(II)

    International Nuclear Information System (INIS)

    The objective of this study is to develope the basic technology necessary for the assurance of structural safety of rock caverns for a permanent radioactive waste repository. The structural analysis of rock caverns subjected to external loads, especially seismic loads, is performed to make sure of the structural integrity of the underground radioactive repository, and finally seeking the sufficient isolation of radioactive wastes from the human life environment during the hazardous lifetime of radionuclides. It is generally known that the structural behavior of rock caverns is greatly influenced by the type of structures and material properties of rock masses around the cavern. In order to develop seismic analysis techniques of underground structures such as the radioactive waste repository, the followings should be studied: depth and site dependence of earthquake characteristics, dynamic material properties of rock, modelling the behavior of rock discontinuities, and structural analysis methods. This study reviews the present status of the research on the aforementioned areas and includes the dynamic structural analysis of the underground cavern subjected to earthquake loading in order to assess the structural stability of an underground radioactive waste repository. (Author)

  11. Bow-tie risk assessment combining causes and effects applied to gasoil storage in an abandoned salt cavern,

    NARCIS (Netherlands)

    Visser, K; Hendriks, D.; Wildenborg, T.; Duijne, H.

    2014-01-01

    A semi-quantitative risk assessment is presented for the storage of gas oil in depleted salt caverns in the Twente region, the Netherlands. It is based on a bow-tie model, in which an incident, leakage of gas oil from the storage system (cavern and wells), is evaluated by assessing its possible caus

  12. Rock Cavern Stability Analysis Under Different Hydro-Geological Conditions Using the Coupled Hydro-Mechanical Model

    Science.gov (United States)

    Chen, H. M.; Zhao, Z. Y.; Choo, L. Q.; Sun, J. P.

    2016-02-01

    Rock cavern stability has a close relationship with the uncertain geological parameters, such as the in situ stress, the joint configurations, and the joint mechanical properties. Therefore, the stability of the rock cavern should be studied with variable geological conditions. In this paper, the coupled hydro-mechanical model, which is under the framework of the discontinuous deformation analysis, is developed to study the underground cavern stability when considering the hydraulic pressure after excavation. Variable geological conditions are taken into account to study their impacts on the seepage rate and the cavern stability, including the in situ stress ratio, joint spacing, and joint dip angle. In addition, the two cases with static hydraulic pressure and without hydraulic pressure are also considered for the comparison. The numerical simulations demonstrate that the coupled approach can capture the cavern behavior better than the other two approaches without the coupling effects.

  13. Cavernous sinus thrombosis secondary to aspergillus granuloma: A case report and review of the literature.

    Science.gov (United States)

    Brenet, Esteban; Boulagnon-Rombi, Camille; N'guyen, Yohan; Litré, Claude-Fabien

    2016-10-01

    Cavernous sinus thrombosis is a rare but serious complication of sphenoid aspergillosis. The rarity of this pathology makes its diagnostic very difficult on a clinical, biological and radiological sense. The authors present a case of cavernous sinus thrombosis with ipsilateral internal carotid artery thrombosis secondary to a non-invasive sphenoid aspergillosis in an immunocompetent host, responsible of a cavernous syndrome associated to a Claude Bernard Horner syndrome. One year after surgery, the patient is still asymptomatic without recurrence. Diagnostic modalities are detailed and several management of this pathology are compared. Surgery is essential in a diagnostic and therapeutic sense. There is no evidence of the interest of adjuvant therapies such as antibiotic and anticoagulation. Concerning the antifungal treatment, the attitude towards a non-invasive sphenoid aspergillosis in an immunocompetent host is unclear. PMID:26860234

  14. Diagnosis and therapy of dural arteriovenous fistula in carotid cavernous sinus region

    International Nuclear Information System (INIS)

    Objective: To investigate the diagnostic and therapeutic methods of dural arteriovenuoe fistula in carotid cavernous sinus region. Methods: Twenty five cases of clinical diagnosis of dural arteriovenous fistula of carotid cavernous sinus region were identified by whole cerebral angiography with seldingers technique. Among them 13 cases underwent endovascular embolized therapy due to large amount of shunt, and another 12 cases were undertaken conservative method of compressing carotid artery of affected side on basis of lesser amount of shunt with a few number of feeding arteries. Results: Conditions of the 25 cases revealed by DSA were selected for the proper indications and then underwent the formentioned therapy with all successful achievement. Conclusion Diagnosis of dural arteriovenous fistula of carotid cavernous sinus region is not difficult. Endovascular embolization is very effective, but the conservative compressing method of carotid artery of the affected side is also an efficient therapy. (authors)

  15. Spectacular test of the fire extinguishing system in the underground cavern of the CMS experiment

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    The enormous rumbling heard 100 m under the earth on Friday, 12 May, was not the start of a foam party at CMS. The Safety Team looked on from the second tier of the CMS underground cavern as it reechoed to the sound of water rushing through the two huge pipes overhead and the air was filled with a mixture of water and foam. A minute later it was a winter wonderland, as fluffy puffs of foam came shooting out of the twelve foam blowers lining the upper cavern walls on both sides. In less than two minutes 7 m3 of water mixed with a small percentage of foaming liquid, was transformed into 5600 m3 of foam and discharged into the cavern.

  16. Tc-99m RBC SPECT in hepatic cavernous hemangioma

    International Nuclear Information System (INIS)

    Hepatic cavernous hemangioma (HCH) is the most common benign hepatic tumor which is detected incidentally during ultrasonography (US) done at health check-up and computed tomography (CT) done for evaluation of metastasis. The aim of the study is to evaluate retrospectively the accuracy of the modality in the diagnosis of HCH at our institution. 229 patients underwent Tc-99m RBC liver SPECT from Nov 16, 1994 to Sep 24, 2001. There were 127 males and 103 females. Their ages ranges from 82 to 17 years with a mean age of 45.8 years. Twenty millicuries of Tc-99m RBCs autologously labeled were injected. SPECT was done in 2-3 hours after the tracer administration and several hours delayed scan was also obtained in some patients. SPECT was performed with low energy high resolution collimators and triple-head gamma camera (MultiSPECT, Siemens medical systems, Inc., Hoffman Estate, III. USA). SPECT was evaluated visually and results were compared with US, CT, MRI, and clinical follow-up. Of the 156 patients a total of 210 hemangiomas were found in RBC liver SPECT. With regard to the distribution of the lesions, 113 cases revealed single; 43 cases depicted multiple HCHs, with 164 in the right lobe and 46 in the left lobe. The size of lesions ranges from 0.9 to 10 cm. Regarding the size of the lesions on radiographic image, 11 were less than 1cm, 144 were 1 to 4 cm, and the others were more than 4 cm in diameter. RBC liver SPECT is none-invasive and very useful method in the diagnosis of hepatic hemangioma in patients with sonographic and computed tomographic suspicion, if the size is more than 1 cm in diameter. The method is used often for confirmation of HCH in our institution

  17. Surgical management of intramedullary cavernous angiomas and analysis pain relief

    Directory of Open Access Journals (Sweden)

    Huang Si Qing

    2014-01-01

    Full Text Available Objective: The objective of this study was to conduct a retrospective analysis of the clinical characteristics of 20 individuals with intramedullary cavernous angiomas (ICA presented with serious pain complaints. This study was to investigate the efficacy of short- and long-term pain relief following surgical resection. Materials and Methods: Between 2006 and 2012, 55 patients with ICA were surgically managed in our institution. Of these 20 (36.4% patients presented with serious pain as a unique clinical feature. Numerical pain scores (NPS: 0-10 were used to assess the patients′ pain levels preoperatively, as well as at 1 month and 1 year postoperatively. All the patients had magnetic resonance imaging (MRI preoperatively and during follow-up. IBM SPSS Statistics 19.0 was used to analysis the outcomes. Results: Of the 20 patients with ICA, 9 (45% required cervical and 11 (55% thoracic surgery. Seven (35% patients presented with radicular pain and 13 (65% presented with central pain. Pain improved from a total mean preoperative score of 8.60 to total mean score of 2.95 (P < 0.01 at one month and 3.35 (P < 0.01 at one year post-surgery. However, the pain symptoms completely disappeared in the long-term follow-up only in three (15% patients. Five (25% patients reported new pain symptoms with no lesion reoccurrence postoperatively. Conclusion: Pain is the common complaint in patients with ICA. Surgery is effective in providing short- and long-term pain relief. However, long-term follow-up measures on postoperative pain levels show that the pain does recur in the months following surgery.

  18. Clitoromegaly caused by cavernous hemangioma: A rare case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Bita Geramizadeh

    2012-01-01

    Full Text Available Hemangioma is a common benign neoplasm, but a location such as the clitoris is very rare. However, it is very important to differentiate clitoral hemangioma from enlargement of the clitoris secondary to androgen excess. To the best of our knowledge, only three cases of clitoromegaly caused by cavernous hemangioma have been reported in the English literature. Herein, we report our experience with a 16-year-old girl who presented with clitoromegaly and normal hormonal assay that turned out to be clitoral cavernous hemangioma after pathologic examination of the clitoral mass.

  19. Simulation of Mechanical Processes in Gas Storage Caverns for Short-Term Energy Storage

    Science.gov (United States)

    Böttcher, Norbert; Nagel, Thomas; Kolditz, Olaf

    2015-04-01

    In recent years, Germany's energy management has started to be transferred from fossil fuels to renewable and sustainable energy carriers. Renewable energy sources such as solar and wind power are subjected by fluctuations, thus the development and extension of energy storage capacities is a priority in German R&D programs. This work is a part of the ANGUS+ Project, funded by the federal ministry of education and research, which investigates the influence of subsurface energy storage on the underground. The utilization of subsurface salt caverns as a long-term storage reservoir for fossil fuels is a common method, since the construction of caverns in salt rock is inexpensive in comparison to solid rock formations due to solution mining. Another advantage of evaporate as host material is the self-healing behaviour of salt rock, thus the cavity can be assumed to be impermeable. In the framework of short-term energy storage (hours to days), caverns can be used as gas storage reservoirs for natural or artificial fuel gases, such as hydrogen, methane, or compressed air, where the operation pressures inside the caverns will fluctuate more frequently. This work investigates the influence of changing operation pressures at high frequencies on the stability of the host rock of gas storage caverns utilizing numerical models. Therefore, we developed a coupled Thermo-Hydro-Mechanical (THM) model based on the finite element method utilizing the open-source software platform OpenGeoSys. The salt behaviour is described by well-known constitutive material models which are capable of predicting creep, self-healing, and dilatancy processes. Our simulations include the thermodynamic behaviour of gas storage process, temperature development and distribution on the cavern boundary, the deformation of the cavern geometry, and the prediction of the dilatancy zone. Based on the numerical results, optimal operation modes can be found for individual caverns, so the risk of host rock damage

  20. Bilateral indirect carotid cavernous fistula post trivial injury- A case report

    Institute of Scientific and Technical Information of China (English)

    Siti Hajar Mat Abu; Hanizasurana Hashim; Tara Mary George; Norfariza Ngah; Adil Hussein

    2013-01-01

    Fifty-seven years old Malay lady, post menopausal with co-morbid of diabetes mellitus and hypertension presented with three months history of bilateral painful red eyes associated with double vision. Examination revealed both eyes proptosis, corkscrew vessels with present of bruit, secondary narrow angle with raised intraocular pressure, 6th cranial nerve palsy, and bilateral venous stasis retinopathy. CT angiogram showed bilateral dilated superior ophthalmic veins with cerebral angiogram findings of bilateral indirect carotid cavernous fistula involving small meningeal vessels. Indirect or dural cavernous sinus Fistula can easily be missed or misdiagnosed. Trivial injury especially in the predisposing patient can initiate the occurrence.

  1. Treatment of traumatic trigeminal-cavernous fistula by coil embolization and compression of carotid artery

    Directory of Open Access Journals (Sweden)

    Yang Xinjian

    2007-01-01

    Full Text Available We report a case of a traumatic cavernous fistula supplied by a persistent primitive trigeminal artery. The process of treatment was unique in this case. Fistula was subcompletely occluded by coiling from primitive trigeminal artery. Residual fistula was helped to form thrombosis by compression of the carotid artery with hand in the procedure. Long-term follow-up was satisfactory. Traumatic cavernous fistula supplied by a persistent primitive trigeminal artery could be treated by embolization and temporal compression of the parent artery might be useful for residual minimal fistula.

  2. Ultimate storage in salt caverns / status report; Endverwahrung von Salzkavernen / Stand der Entwicklung

    Energy Technology Data Exchange (ETDEWEB)

    Crotogino, F.; Schmidt, U. [Kavernen Bau- und Betriebs-GmbH, Hannover (Germany)

    1998-12-31

    The contribution reviews the state of knowledge on final storage in salt caverns. The long-term effects of a hermetically sealed, brine-filled cavern are discussed. So far, there are no valid predictions. (orig.) [Deutsch] In dem Beitrag wird der derzeitige Kenntnis- und Diskussionsstand zur Endverwahrung von Salzkavernen zusammengefasst. Aufbauend auf den bisher vorliegenden Vorstellungen zur Soleimpraegnation bei einem Innendruck, der nahezu dem Ueberlagerungsdruck entspricht, werden die denkbaren langfristigen Auswirkungen einer vollstaendig abgeschlossenen solegefuellten Kaverne skizziert; belastbare Prognosen sind derzeit noch nicht moeglich. (orig.)

  3. Commissioning of the CMS Cryogenic System After Final Installation in the Underground Cavern

    CERN Document Server

    Dupont, T; Perinic, G

    2010-01-01

    After having served for the surface tests of the Compact Muon Solenoid (CMS) magnet, the cold box and ancillaries of the CMS helium refrigerator have been dismantled, moved and re-installed in the USC55 cavern in 2007. The full re-commissioning in the cavern has been followed by several tests of the refrigerator to confirm its nominal performance before it was used for the magnet and detector tests in 2008. During these tests the safety modes of the refrigeration system have been tested and improved. After a nine-year project both, the magnet and the refrigeration system are now ready for the CMS operation.

  4. Cavernous Hemangioma of the External Canal, Tympanic Membrane, and Middle Ear Cleft: A Case Report.

    Science.gov (United States)

    Odat, Haitham; Al-Qudah, Mohannad; Al-Qudah, Mohammad A

    2016-06-01

    Cavernous hemangioma involving the external canal, tympanic membrane, and middle ear cavity is extremely rare. We present a case of a 45-year-old woman who had progressive right sided decreased hearing, pulsatile tinnitus, and aural fullness of 7 months duration. Microscopic examination, imaging studies, surgical treatment, and histological evaluation are reported. To the best of our knowledge, this is the first case of cavernous hemangioma with simultaneous involvement of the external ear, tympanic membrane, middle ear, and attic reported in English literature. PMID:26304856

  5. A NOVEL PROCESS TO USE SALT CAVERNS TO RECEIVE SHIP BORNE LNG

    Energy Technology Data Exchange (ETDEWEB)

    Michael M. McCall; William M. Bishop; Marcus Krekel; James F. Davis; D. Braxton Scherz

    2005-05-31

    This cooperative research project validates use of man made salt caverns to receive and store the cargoes of LNG ships in lieu of large liquid LNG tanks. Salt caverns will not tolerate direct injection of LNG because it is a cryogenic liquid, too cold for contact with salt. This research confirmed the technical processes and the economic benefits of pressuring the LNG up to dense phase, warming it to salt compatible temperatures and then directly injecting the dense phase gas into salt caverns for storage. The use of salt caverns to store natural gas sourced from LNG imports, particularly when located offshore, provides a highly secure, large scale and lower cost import facility as an alternative to tank based LNG import terminals. This design can unload a ship in the same time as unloading at a tank based terminal. The Strategic Petroleum Reserve uses man made salt caverns to securely store large quantities of crude oil. Similarly, this project describes a novel application of salt cavern gas storage technologies used for the first time in conjunction with LNG receiving. The energy industry uses man made salt caverns to store an array of gases and liquids but has never used man made salt caverns directly in the importation of LNG. This project has adapted and expanded the field of salt cavern storage technology and combined it with novel equipment and processes to accommodate LNG importation. The salt cavern based LNG receiving terminal described in the project can be located onshore or offshore, but the focus of the design and cost estimates has been on an offshore location, away from congested channels and ports. The salt cavern based terminal can provide large volumes of gas storage, high deliverability from storage, and is simplified in operation compared to tank based LNG terminals. Phase I of this project included mathematical modeling that proved a salt cavern based receiving terminal could be built at lower capital cost, and would have significantly higher

  6. Roentgenological investigation of cavernous sinus structure with special reference to paracavernous cranial nerves

    International Nuclear Information System (INIS)

    We have evaluated the anatomical structure of cavernous sinuses in parasellar blocks obtained from adult cadavers to gain clinically useful information. Ten microdissectional studies of parasellar blocks (20 sides of cavernous sinus) were carried out with special emphasis on the course of paracavernous cranial nerves (3rd to 6th). These were also examined on plain radiographs. Secondly, CT investigations of the cavernous sinuses (notably as to paracavernous cranial nerves) were undertaken in twenty clinical cases having presumed parasellar lesions and in three parasellar blocks from cadavers. The results from microdisectional studies and plain radiographs were as follows. It was found that the 3rd cranial nerve entered the lateral wall of the cavernous sinus close to the antero-inferior part of the posterior clinoid on lateral projection. The 4th cranial nerve, on the other hand, entered near the postero-inferior portion of the posterior clinoid on the same view. Variations in Parkinson's triangle were fairly often noted, although marked asymmetry was not seen in individual cases. From CT findings, it was found that a postenhanced, magnified direct coronal study was essential for identifying paracavernous cranial nerves more clearly. The 3rd and 5th cranial nerves were fairly well identified on axial and coronal projections. Careful radiological investigation including plain skull radiographs and CT seems to be of value for those who diagnose or treat parasellar lesions. (orig.)

  7. Endoscopic approaches to brainstem cavernous malformations: Case series and review of the literature

    Directory of Open Access Journals (Sweden)

    Nikhil R Nayak

    2015-01-01

    Conclusion: The endoscope is a promising adjunct to the neurosurgeon′s ability to approach difficult to access brainstem cavernous malformations. It allows the surgeon to achieve well-illuminated, panoramic views, and by combining approaches, can provide minimally invasive access to most regions of the brainstem.

  8. Giant Cavernous Aneurysm Associated with a Persistent Trigeminal Artery and Persistent Otic Artery

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Chang Wei; Xie, Xiao Dong; Yang, Zhi Gang; Wang, Chao Hua; You, Chao; Mao, Bo Yong; He, Min; Sun, Hong [West China Hospital, Sichuan University, Sichuan (China)

    2009-10-15

    Primitive trigeminal artery (PTA) and primitive otic artery (POA) is a very rare entity in adult life. We present a case of PTA and POA associated with a giant unruptured cavernous aneurysm in a 54-year-old woman. The PTA and the POA arose from the sac of the aneurysm directly, which greatly complicated endovascular therapy management

  9. Giant Cavernous Aneurysm Associated with a Persistent Trigeminal Artery and Persistent Otic Artery

    Science.gov (United States)

    Zhang, Chang-wei; Yang, Zhi-gang; Wang, Chao-hua; You, Chao; Mao, Bo-yong; He, Min; Sun, Hong

    2009-01-01

    Primitive trigeminal artery (PTA) and primitive otic artery (POA) is a very rare entity in adult life. We present a case of PTA and POA associated with a giant unruptured cavernous aneurysm in a 54-year-old woman. The PTA and the POA arose from the sac of the aneurysm directly, which greatly complicated endovascular therapy management. PMID:19721839

  10. Post-Traumatic Cavernous Fistula Fed by Persistent Trigeminal Artery: Treatment by GDC Embolisation

    Science.gov (United States)

    Deol, P.S.; Mishra, N.K.; Gupta, V.; Gaikwad, S.B.; Garg, A.; Singh, N.

    2001-01-01

    Summary A case of traumatic persistent primitive trigeminal artery (PPTA) cavernous sinus fistula treated with GDC embolisation is reported. Because of the small lumen of PPTA, posteriorly directed course and flow contribution from the posterior circulation, balloon embolisation via the carotid system was not considered appropriate. The fistula was successfully closed by GDC embolisation. PMID:20663331

  11. Intravascular treatment of a cavernous fistula by rupture of a traumatic carotid trigeminal aneurysm. Case reports

    Energy Technology Data Exchange (ETDEWEB)

    Flandroy, P.; Collignon, J.; Lacour, P.; Marsault, C.; Stevenaert, A.

    1987-05-01

    The authors report the particular treatment of a traumatic cavernous fistula caused by the rupture of an exceptional lesion: a false aneurysm of the C5 segment of the right carotid artery situated at the origin of a persistent trigeminal artery.

  12. Arteriovenous Malformation in Temporal Lobe Presenting as Contralateral Ocular Symptoms Mimicking Carotid-Cavernous Fistula

    Directory of Open Access Journals (Sweden)

    Fadzillah Mohd-Tahir

    2013-01-01

    Full Text Available Aim. To report a rare case of arteriovenous malformation in temporal lobe presenting as contralateral orbital symptoms mimicking carotid-cavernous fistula. Method. Interventional case report. Results. A 31-year-old Malay gentleman presented with 2-month history of painful progressive exophthalmos of his left eye associated with recurrent headache, diplopia, and reduced vision. Ocular examination revealed congestive nonpulsating 7 mm exophthalmos of the left eye with no restriction of movements in all direction. There was diplopia in left lateral gaze. Left IOP was elevated at 29 mmHg. Left eye retinal vessels were slightly dilated and tortuous. CT scan was performed and showed right temporal arteriovenous malformation with a nidus of 3.8 cm × 2.5 cm with right middle cerebral artery as feeding artery. There was dilated left superior ophthalmic vein of 0.9 mm in diameter with enlarged left cavernous sinus. MRA and carotid angiogram confirmed right temporal arteriovenous malformation with no carotid-cavernous fistula. Most of the intracranial drainage was via left cavernous sinus. His signs and symptoms dramatically improved following successful embolisation, completely resolved after one year. Conclusion. Intracranial arteriovenous malformation is rarely presented with primary ocular presentation. Early intervention would salvage the eyes and prevent patients from more disaster morbidity or fatality commonly due to intracranial haemorrhage.

  13. Multiparameter monitoring of a salt cavern collapse (Cerville-Buissoncourt site, France)

    Science.gov (United States)

    Daupley, Xavier; Fabriol, Robert; Contrucci, Isabelle; Bernardie, Séverine; Cao, Ngoc-Tuyen; Jousset, Philippe; Klein, Emmanuelle; Lebert, François; Behrooz, Bazargan

    2010-05-01

    Since 2004, in the framework of GISOS (Scientific Interest Group on the Impact and Safety of Underground Structures), INERIS and BRGM participated in a monitoring experiment of a salt cavern located in the Lorrain salt basin, few kilometers away from Nancy (France). The site is located in the mining concession of Cerville Buissoncourt, owned by SOLVAY. The mining method used consists in extracting the full salt formation by solution mining until the collapse of the overburden. Thereby, the opportunity offered by this collapse was taken to test various monitoring techniques to detect its early warning signs and to improve scientific and technical knowledge of salt caverns mechanical behavior and evolution. Several geotechnical and geophysical methods have been further implemented on site in addition to the monitoring carried out by the operator, which are : microseismic, hydroacoustic, broadband seismology, surface measurements (tacheometer and RTK GPS), drilling extensometry, hydro-chemistry. In early 2009, after several significant changes in the cavity behavior, and as it had reached its critical dimensions, the operator decided to trigger its collapse. For this, pumping operations in the cavern were carried out to reduce brine level and hydrostatic pressure that contributed previously to the cavern stability. These operations, conducted during 4 days, were monitored in real time. They led to the collapse of the cavity on February 13th, 2009. Comparative analysis of the measurements acquired by the several monitoring techniques allows describing in detail the different evolution stages of the cavity and the early warning signs of its collapse.

  14. The Magnetic Resonance hnage and Pathology of Spinal Cord Cavernous Hemangioma

    Institute of Scientific and Technical Information of China (English)

    同志勤; 白斌; 同志超; 宋广义; 赵京龙

    2002-01-01

    Objective To investigate the characteristics of magnetic resonance image(MRI) of spinal cord cavernous hemangioma. Methods Six cases of spinal cord cavernous heman-gioma diagnosed by MRI and confirmed by pathology were reviewed. The characteristics of MRI wereanalgzed and correlated with pathological characteristics of spinal cord cavernous hemangioma. ResultsIn 4 cases, the tumors were located in thoracic segment of the spinal cord and 2 in cervical cord. Alllesions were solitary and the spinal cords were normal or a little thicker. The MRI showed that the im-ages of focus were ball-like popcorn or mulberry with mixed signal,with short T2 signal around the fo-cus. Under microscope, the hemangioma was composed of highly expanded blood sinusoids and its wallwas thin and consisted of flat epithelial cells. T'here were some red blood cells in the cavity of the sinu-soid and a little fibrous tissue in the diazoma between blood sinusoids. And also some fresh and old hem-orrhages could be seen in the specimen. Conclusion MRI has high sensitivity and specificity in thediagnosis of spinal cavernous hemangioma.

  15. Progress on CMS detector lowering: the YE+2 section arriving in the cavern

    CERN Multimedia

    2006-01-01

    On 12 December, a further section of the detector (YE+2) containing the cathode strip chamber made the 10-hour journey underground. This piece is 16 m high and weighs 880 tonnes. There are now four sections of the detector in the experimental cavern, with a further 11 to follow.

  16. Gas-cooled HTR reactor installed in a pressure vessel cavern

    International Nuclear Information System (INIS)

    A pebble-bed reactor in a pressure vessel cavern is described which has a reflector which in case of accidents with pressure equalisation between cold gas and hot gas transfers the resulting loads to a lateral thermal shield constructed in the form of a pressure-tight metal cylinder. (TK)

  17. Thermo-mechanical modelling of cyclic gas storage applications in salt caverns

    Science.gov (United States)

    Böttcher, Norbert; Watanabe, Norihiro; Görke, Uwe-Jens; Kolditz, Olaf; Nagel, Thomas

    2016-04-01

    Due to the growing importance of renewable energy sources it becomes more and more necessary to investigate energy storage potentials. One major way to store energy is the power-to-gas concept. Excessive electrical energy can be used either to produce hydrogen or methane by electrolysis or methanation or to compress air, respectively. Those produced gases can then be stored in artificial salt caverns, which are constructed in large salt formations by solution mining. In combination with renewable energy sources, the power-to-gas concept is subjected to fluctuations. Compression and expansion of the storage gases lead to temperature differences within the salt rock. The variations can advance several metres into the host rock, influencing its material behaviour, inducing thermal stresses and altering the creep response. To investigate the temperature influence on the cavern capacity, we have developed a numerical model to simulate the thermo-mechanical behaviour of salt caverns during cyclic gas storage. The model considers the thermodynamic behaviour of the stored gases as well as the heat transport and the temperature dependent material properties of the host rock. Therefore, we utilized well-known constitutive thermo-visco-plastic material models, implemented into the open source-scientific software OpenGeoSys. Both thermal and mechanical processes are solved using a finite element approach, connected via a staggered coupling scheme. The model allows the assessment of the structural safety as well as the convergence of the salt caverns.

  18. Preliminary Technical and Legal Evaluation of Disposing of Nonhazardous Oil Field Waste into Salt Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Ayers, Robert C.; Caudle, Dan; Elcock, Deborah; Raivel, Mary; Veil, John; and Grunewald, Ben

    1999-01-21

    This report presents an initial evaluation of the suitability, feasibility, and legality of using salt caverns for disposal of nonhazardous oil field wastes. Given the preliminary and general nature of this report, we recognize that some of our findings and conclusions maybe speculative and subject to change upon further research on this topic.

  19. Higher Rate of Intracerebral Hemorrhage in Hispanic Patients with Cerebral Cavernous Malformation

    OpenAIRE

    Jenson, Amanda V.; Rodriguez, Gustavo J.; Alvarado, Luis A.; Cruz-Flores, Salvador; Maud, Alberto

    2015-01-01

    Cerebral cavernous malformations (CCM) are vascular malformations prone to intracerebral hemorrhage and epilepsy. Studies about the natural history and clinical presentation in the Hispanic population are lacking [7]. Retrospectively, we identified demographics and clinical features of Hispanic patients with CCM in our neurology clinic. Comparison with studies in the non-Hispanic White population with CCM was conducted.

  20. Follow-up of endovascular treatment of direct carotid-cavernous fistulas

    International Nuclear Information System (INIS)

    Direct carotid-cavernous fistula (CCF) is a direct communication between the internal carotid artery (ICA) and the cavernous sinus. Some patients treated with detachable balloons develop pseudoaneurysms or present with a true aneurysm recanalization in the cavernous ICA with poorly known long-term radiological and clinical progression. The objective of the present study was to evaluate the long-term clinical and radiological progression of patients treated with detachable balloons. The present study evaluated 13 patients previously treated for direct CCF by an endovascular approach. The follow-up period ranged between 19 and 128 months. Ophthalmological evaluation demonstrated alterations in eight patients (61.5%). All of these alterations were already present from the moment of the treatment and displayed no signs of progression. Cranial magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) were performed in all patients, and 11 pseudoaneurysms were demonstrated in ten of the 11 patients in whom ICA patency had been preserved. Five patients were submitted for cerebral digital subtraction angiography (DSA) to characterize the pseudoaneurysms previously observed on MRA studies, with no significant differences in morphology, size, aneurismal neck, and number of lesions. Endovascular treatment of direct CCF with detachable balloons has been shown to be a long-term effective and stable therapeutic method. The authors found asymptomatic pseudoaneurysms in 91% of cases where the ICA patency was preserved. MRI and MRA demonstrated an accuracy similar to that of DSA in the diagnosis of pseudoaneurysms of cavernous ICA. (orig.)

  1. Follow-up of endovascular treatment of direct carotid-cavernous fistulas

    Energy Technology Data Exchange (ETDEWEB)

    Marques, Marcio C.P.; Nalli, Darcio R.; Fonseca, Jose Roberto F.; Nogueira, Roberto G.; Abdala, Nitamar [Federal University of Sao Paulo, Department of Radiology, Sao Paulo, SP (Brazil); Pereira Caldas, Jose Guilherme M. [Sao Paulo University, Department of Radiology, Sao Paulo (Brazil)

    2010-12-15

    Direct carotid-cavernous fistula (CCF) is a direct communication between the internal carotid artery (ICA) and the cavernous sinus. Some patients treated with detachable balloons develop pseudoaneurysms or present with a true aneurysm recanalization in the cavernous ICA with poorly known long-term radiological and clinical progression. The objective of the present study was to evaluate the long-term clinical and radiological progression of patients treated with detachable balloons. The present study evaluated 13 patients previously treated for direct CCF by an endovascular approach. The follow-up period ranged between 19 and 128 months. Ophthalmological evaluation demonstrated alterations in eight patients (61.5%). All of these alterations were already present from the moment of the treatment and displayed no signs of progression. Cranial magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) were performed in all patients, and 11 pseudoaneurysms were demonstrated in ten of the 11 patients in whom ICA patency had been preserved. Five patients were submitted for cerebral digital subtraction angiography (DSA) to characterize the pseudoaneurysms previously observed on MRA studies, with no significant differences in morphology, size, aneurismal neck, and number of lesions. Endovascular treatment of direct CCF with detachable balloons has been shown to be a long-term effective and stable therapeutic method. The authors found asymptomatic pseudoaneurysms in 91% of cases where the ICA patency was preserved. MRI and MRA demonstrated an accuracy similar to that of DSA in the diagnosis of pseudoaneurysms of cavernous ICA. (orig.)

  2. The Role of Palliative Radiosurgery When Cancer Invades the Cavernous Sinus

    International Nuclear Information System (INIS)

    Purpose: Involvement of the cavernous sinus by direct invasion from skull base cancer or from metastatic spread of cancers is a challenging problem. We evaluated the role of stereotactic radiosurgery (SRS) in the treatment of patients who developed cavernous sinus metastases or direct invasion. Methods and Materials: We retrospectively reviewed the data from 37 patients who had cavernous sinus metastases or had cavernous sinus invasion from adjacent skull base cancers and who underwent SRS between 1992 and 2006 at University of Pittsburgh Medical Center. The median patient age was 57.8 years. Previous adjuvant management included fractionated radiotherapy in 8, chemotherapy in 16, and both radiotherapy and chemotherapy in 5. The primary sites of metastases or invasion were nasopharyngeal carcinoma (n = 7), parotid gland carcinoma (n = 7), and metastases from systemic cancer (n = 23). The median target volume was 6.3 cm3 (range, 0.3-33.6), and the median margin dose was 14 Gy (range, 12-20). Results: At a mean of 12.9 months (range, 0.8-63.9), 32 patients had died and 5 were living. The overall survival rate after SRS was 36.6% and 19.4% at 1 and 2 years, respectively. Progression-free survival was related to a greater marginal dose. After SRS, 12 (35.3%) of 34 patients with neurologic symptoms exhibited improvement. SRS early after diagnosis was significantly associated with improvement of cranial nerve dysfunction. Conclusion: SRS is a minimally invasive palliative option for patients whose cancer has invaded the cavernous sinus. The benefits for cranial nerve deficits are best when SRS is performed early

  3. Endovascular management of dural carotid-cavernous sinus fistulas in 141 patients

    Energy Technology Data Exchange (ETDEWEB)

    Kirsch, M. [Alfried Krupp Krankenhaus, Klinik fuer Radiologie und Neuroradiologie, Essen (Germany); Universitaetsklinikum Greifswald, Institut fuer Diagnostische Radiologie und Neuroradiologie, Greifswald (Germany); Henkes, H.; Liebig, T.; Weber, W.; Golik, S.; Kuehne, D. [Alfried Krupp Krankenhaus, Klinik fuer Radiologie und Neuroradiologie, Essen (Germany); Esser, J. [Universitaetsklinikum Essen, Zentrum fuer Augenheilkunde, Essen (Germany)

    2006-07-15

    Introduction: The purpose of this study was to evaluate the single-centre experience with transvenous coil treatment of dural carotid-cavernous sinus fistulas. Methods: Between November 1991 and December 2005, a total of 141 patients (112 female) with dural carotid-cavernous sinus fistula underwent 161 transvenous treatment sessions. The patient files and angiograms were analysed retrospectively. Clinical signs and symptoms included chemosis (94%), exophthalmos (87%), cranial nerve palsy (54%), increased intraocular pressure (60%), diplopia (51%), and impaired vision (28%). Angiography revealed in addition cortical drainage in 34% of the patients. Partial arterial embolization was carried out in 23% of the patients. Transvenous treatment comprised in by far the majority of patients complete filling of the cavernous sinus and the adjacent segment of the superior and inferior ophthalmic vein with detachable coils. Complete interruption of the arteriovenous shunt was achieved in 81% of the patients. A minor residual shunt (without cortical or ocular drainage) remained in 13%, a significant residual shunt (with cortical or ocular drainage) remained in 4%, and the attempted treatment failed in 2%. There was a tendency for ocular pressure-related symptoms to resolve rapidly, while cranial nerve palsy and diplopia improved slowly (65%) or did not change (11%). The 39 patients with visual impairment recovered within the first 2 weeks after endovascular treatment. After complete interruption of the arteriovenous shunt, no recurrence was observed. The transvenous coil occlusion of the superior and inferior ophthalmic veins and the cavernous sinus of the symptomatic eye is a highly efficient and safe treatment in dural carotid-cavernous sinus fistulas. In the majority of patients a significant and permanent improvement in clinical signs and symptoms can be achieved. (orig.)

  4. Neurturin enhances the recovery of erectile function following bilateral cavernous nerve crush injury in the rat

    Directory of Open Access Journals (Sweden)

    Klein Robert D

    2007-03-01

    Full Text Available Abstract Background The molecular mechanisms responsible for the survival and preservation of function for adult parasympathetic ganglion neurons following injury remain incompletely understood. However, advances in the neurobiology of growth factors, neural development, and prevention of cell death have led to a surge of clinical interest for protective and regenerative neuromodulatory strategies, as surgical therapies for prostate, bladder, and colorectal cancers often result in neuronal axotomy and debilitating loss of sexual function or continence. In vitro studies have identified neurturin, a glial cell line-derived neurotrophic factor, as a neuromodulator for pelvic cholinergic neurons. We present the first in vivo report of the effects of neurturin upon the recovery of erectile function following bilateral cavernous nerve crush injury in the rat. Methods In these experiments, groups (n = 8 each consisted of uninjured controls and animals treated with injection of albumin (blinded crush control group, extended release neurotrophin-4 or neurturin to the site of cavernous nerve crush injury (100 μg per animal. After 5 weeks, recovery of erectile function (treatment effect was assessed by cavernous nerve electrostimulation and peak aortic pressures were measured. Investigators were unblinded to specific treatments after statistical analyses were completed. Results Erectile dysfunction was not observed in the sham group (mean maximal intracavernous pressure [ICP] increase of 117.5 ± 7.3 cmH2O, whereas nerve injury and albumin treatment (control produced a significant reduction in ICP elevation of 40.0 ± 6.3 cmH2O. Neurturin facilitated the preservation of erectile function, with an ICP increase of 55% at 62.0 ± 9.2 cmH2O (p Conclusion Treatment with neurturin at the site of cavernous nerve crush injury facilitates recovery of erectile function. Results support further investigation of neurturin as a neuroprotective and/or neuroregenerative

  5. Carotid-cavernous fistula caused by laceration of persistent fetal trigeminal artery treated with single catheter coil embolization

    Directory of Open Access Journals (Sweden)

    Benjamin L Brown

    2012-01-01

    Full Text Available We present the endovascular treatment of traumatic carotid-cavernous fistula from persistent fetal trigeminal artery (PFTA laceration. To date, there are six such cases of traumatic PFTA-cavernous fistulas reported in the literature. These injuries can pose a unique challenge in that rupture of a PFTA in its course through the cavernous sinus may produce a fistula feeding from both anterior and posterior circulations. Previously, these have been treated with dual catheter coil embolization from the carotid and basilar systems. We utilize a single catheter technique accessing the cavernous sinus through the origin of the PFTA on the internal carotid. Both anterior and posterior fistula components may be embolized through this single access. This represents a simple yet safe treatment option.

  6. Western Portion IKONOS and Landsat ETM Merge Satellite Imagery for Carlsbad Caverns National Park Vegetation Mapping Project

    Data.gov (United States)

    National Park Service, Department of the Interior — IKONOS and Landsat ETM+ image merge for Carlsbad Caverns National Park, New Mexico. The image has a spatial resolution of 12 meters and is comprised of 11 layers....

  7. Persistent trigeminal artery arising from the arterial ring/fenestration of the cavernous segment of the internal carotid artery.

    Science.gov (United States)

    Uchino, Akira; Saito, Naoko; Kurita, Hiroki; Ishihara, Shoichiro

    2012-09-01

    A persistent trigeminal artery (PTA) is the most common carotid-vertebrobasilar anastomosis, usually arising from the cavernous or precavernous segment of the internal carotid artery (ICA) and connecting to the distal basilar artery. There are two types of PTA, lateral and medial. We present the first case of a lateral-type PTA arising from the large arterial ring/fenestration of the cavernous segment of the left ICA with findings from both magnetic resonance angiography and selective catheter angiography. PMID:22215430

  8. Commercial potential of natural gas storage in lined rock caverns (LRC)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    The geologic conditions in many regions of the United States will not permit the development of economical high-deliverability gas storage in salt caverns. These regions include the entire Eastern Seaboard; several northern states, notably Minnesota and Wisconsin; many of the Rocky Mountain States; and most of the Pacific Northwest. In late 1997, the United States Department of Energy (USDOE) Federal Energy Technology Center engaged Sofregaz US to investigate the commercialization potential of natural gas storage in Lined Rock Caverns (LRC). Sofregaz US teamed with Gaz de France and Sydkraft, who had formed a consortium, called LRC, to perform the study for the USDOE. Underground storage of natural gas is generally achieved in depleted oil and gas fields, aquifers, and solution-mined salt caverns. These storage technologies require specific geologic conditions. Unlined rock caverns have been used for decades to store hydrocarbons - mostly liquids such as crude oil, butane, and propane. The maximum operating pressure in unlined rock caverns is limited, since the host rock is never entirely impervious. The LRC technology allows a significant increase in the maximum operating pressure over the unlined storage cavern concept, since the gas in storage is completely contained with an impervious liner. The LRC technology has been under development in Sweden by Sydkraft since 1987. The development process has included extensive technical studies, laboratory testing, field tests, and most recently includes a storage facility being constructed in southern Sweden (Skallen). The LRC development effort has shown that the concept is technically and economically viable. The Skallen storage facility will have a rock cover of 115 meters (375 feet), a storage volume of 40,000 cubic meters (250,000 petroleum barrels), and a maximum operating pressure of 20 MPa (2,900 psi). There is a potential for commercialization of the LRC technology in the United States. Two regions were studied

  9. Cavern disposal concepts for HLW/SF: assuring operational practicality and safety with maximum programme flexibility

    International Nuclear Information System (INIS)

    Most conventional engineered barrier system (EBS) designs for HLW/SF repositories are based on concepts developed in the 1970s and 1980s that assured feasibility with high margins of safety, in order to convince national decision makers to proceed with geological disposal despite technological uncertainties. In the interval since the advent of such 'feasibility designs', significant progress has been made in reducing technological uncertainties, which has lead to a growing awareness of other, equally important uncertainties in operational implementation and challenges regarding social acceptance in many new, emerging national repository programs. As indicated by the NUMO repository concept catalogue study (NUMO, 2004), there are advantages in reassessing how previous designs can be modified and optimised in the light of improved system understanding, allowing a robust EBS to be flexibly implemented to meet nation-specific and site-specific conditions. Full-scale emplacement demonstrations, particularly those carried out underground, have highlighted many of the practical issues to be addressed; e.g., handling of compacted bentonite in humid conditions, use of concrete for support infrastructure, remote handling of heavy radioactive packages in confined conditions, quality inspection, monitoring / ease of retrieval of emplaced packages and institutional control. The CAvern REtrievable (CARE) concept reduces or avoids such issues by emplacement of HLW or SF within multi-purpose transportation / storage / disposal casks in large ventilated caverns at a depth of several hundred metres. The facility allows the caverns to serve as inspectable stores for an extended period of time (up to a few hundred years) until a decision is made to close them. At this point the caverns are backfilled and sealed as a final repository, effectively with the same safety case components as conventional 'feasibility designs'. In terms of operational practicality an d safety, the CARE

  10. Commercial potential of natural gas storage in lined rock caverns (LRC); FINAL

    International Nuclear Information System (INIS)

    The geologic conditions in many regions of the United States will not permit the development of economical high-deliverability gas storage in salt caverns. These regions include the entire Eastern Seaboard; several northern states, notably Minnesota and Wisconsin; many of the Rocky Mountain States; and most of the Pacific Northwest. In late 1997, the United States Department of Energy (USDOE) Federal Energy Technology Center engaged Sofregaz US to investigate the commercialization potential of natural gas storage in Lined Rock Caverns (LRC). Sofregaz US teamed with Gaz de France and Sydkraft, who had formed a consortium, called LRC, to perform the study for the USDOE. Underground storage of natural gas is generally achieved in depleted oil and gas fields, aquifers, and solution-mined salt caverns. These storage technologies require specific geologic conditions. Unlined rock caverns have been used for decades to store hydrocarbons - mostly liquids such as crude oil, butane, and propane. The maximum operating pressure in unlined rock caverns is limited, since the host rock is never entirely impervious. The LRC technology allows a significant increase in the maximum operating pressure over the unlined storage cavern concept, since the gas in storage is completely contained with an impervious liner. The LRC technology has been under development in Sweden by Sydkraft since 1987. The development process has included extensive technical studies, laboratory testing, field tests, and most recently includes a storage facility being constructed in southern Sweden (Skallen). The LRC development effort has shown that the concept is technically and economically viable. The Skallen storage facility will have a rock cover of 115 meters (375 feet), a storage volume of 40,000 cubic meters (250,000 petroleum barrels), and a maximum operating pressure of 20 MPa (2,900 psi). There is a potential for commercialization of the LRC technology in the United States. Two regions were studied

  11. Phase II Study to Assess the Efficacy of Hypofractionated Stereotactic Radiotherapy in Patients With Large Cavernous Sinus Hemangiomas

    International Nuclear Information System (INIS)

    Purpose: Cavernous sinus hemangioma is a rare vascular tumor. The direct microsurgical approach usually results in massive hemorrhage. Although radiosurgery plays an important role in managing cavernous sinus hemangiomas as a treatment alternative to microsurgery, the potential for increased toxicity with single-session treatment of large tumors is a concern. The purpose of this study was to assess the efficacy of hypofractionated stereotactic radiotherapy in patients with large cavernous sinus hemangiomas. Methods: Fourteen patients with large (volume >20 cm3) cavernous sinus hemangiomas were enrolled in a prospective Phase II study between December 2007 and December 2010. The hypofractionated stereotactic radiotherapy dose was 21 Gy delivered in 3 fractions. Results: After a mean follow-up of 15 months (range, 6–36 months), the magnetic resonance images showed a mean of 77% tumor volume reduction (range, 44–99%). Among the 6 patients with cranial nerve impairments before hypofractionated stereotactic radiotherapy, 1 achieved symptomatic complete resolution and 5 had improvement. No radiotherapy-related complications were observed during follow-up. Conclusion: Our current experience, though preliminary, substantiates the role of hypofractionated stereotactic radiotherapy for large cavernous sinus hemangiomas. Although a longer and more extensive follow-up is needed, hypofractionated stereotactic radiotherapy of 21 Gy delivered in 3 fractions is effective in reducing the tumor volume without causing any new deficits and can be considered as a treatment modality for large cavernous sinus hemangiomas.

  12. Radiation-induced intracerebral cavernous angiomas in children with malignant brain tumors. A report of two cases

    International Nuclear Information System (INIS)

    Cavernous angiomas forming in the brain after radiation therapy for pediatric brain tumors have recently attracted special interest as a late complication of radiation therapy. We report here on two children with malignant brain tumors who developed intracerebral cavernous angiomas 4 to 5 years after radiation therapy. A 14-year-old girl with a primitive neuroectodermal tumor developed a cavernous angioma in the hypothalamus after being irradiated with 55 Gy 4 years ago. The second case, 13-year-old boy with a pineal mixed germ cell tumor showed a cavernous angioma at the thalamus 5 years after receiving radiation therapy with a dose of 60 Gy. Both patients did not show any abnormal symptoms and the cavernous angiomas diagnoses were made with MRI findings. A review of 20 reported cases of radiation-induced cavernous angiomas in the brain revealed some characteristic findings. Eighteen of the 20 cases were children, fourteen cases developed hemorrhage, the radiation dose administered was distributed between 18-60 Gy (median dose of 43.5 Gy), and the median latent period was 7.5 years (range: 2-21 years). As a differential diagnosis for the recurrent tumor is guite difficult in most cases, it is necessary to observe patients who developed angioma-like lesions in the irradiated area carefully. (author)

  13. 27 Febuary 2012 - US DoE Associate Director of Science for High Energy Physics J. Siegrist visiting the LHC superconducting magnet test hall with adviser J.-P. Koutchouk and engineer M. Bajko; in CMS experimental cavern with Spokesperson J. Incadela;in ATLAS experimental cavern with Deputy Spokesperson A. Lankford; in ALICE experimental cavern with Spokesperson P. Giubellino; signing the guest book with Director for Accelerators and Technology S. Myers.

    CERN Multimedia

    Laurent Egli

    2012-01-01

    27 Febuary 2012 - US DoE Associate Director of Science for High Energy Physics J. Siegrist visiting the LHC superconducting magnet test hall with adviser J.-P. Koutchouk and engineer M. Bajko; in CMS experimental cavern with Spokesperson J. Incadela;in ATLAS experimental cavern with Deputy Spokesperson A. Lankford; in ALICE experimental cavern with Spokesperson P. Giubellino; signing the guest book with Director for Accelerators and Technology S. Myers.

  14. Strategic Petroleum Reserve (SPR) oil storage cavern sulphur mines 2-4-5 certification tests and analysis. Part I: 1981 testing. Part II: 1982 testing

    Energy Technology Data Exchange (ETDEWEB)

    Beasley, R.R.

    1982-12-01

    Well leak tests and a cavern pressure were conducted in June through December 1981, and are described in Part I. The tests did not indicate conclusively that there was no leakage from the cavern, but the data indicate that cavern structural failure during oil storage is unlikely. The test results indicated that retesting and well workover were desirable prior to making a decision on the cavern use. Well leak tests were conducted in March through May 1982, and are described in Part II. The tests indicated that there was no significant leakage from wells 2 and 4 but that the leakage from wells 2A and 5 exceeded the DOE criterion. Because of the proximity of cavern 2-4-5 to the edge of the salt, this cavern should be considered for only one fill/withdrawal cycle prior to extensive reevaluation. 57 figures, 17 tables.

  15. A novel support system for shallow buried caverns based on the mining method

    Science.gov (United States)

    Wen-Qi, Ding; Ya-Fei, Qiao; Yue-Lang, Jin; Qing-Zhao, Zhang

    2016-02-01

    In order to maintain the original appearance of the rocks on a cavern roof and protect the ground environment, a new supporting method for shallow-buried caverns is proposed. This study investigates the design theory and construction process. Based to this method, some crisscross small tunnel sheds are embedded in the overburden layer. Hence a supporting system of interaction between surrounding rocks and supporting structures is formed. By combining the numerical calculation with monitoring measurement, we found that the distribution of calculated deformation generally agreed with the monitoring measurements. The monitoring results revealed that the proportion of rock shelf load-bearing reached 47%. The self-bearing capacity of the surrounding rocks is brought into significantly play.

  16. External carotid artery embolization of dural arteriovenous malformations involving the cavernous sinus

    International Nuclear Information System (INIS)

    Nine patients with dural arteriovenous malformations (AVMs) in the region of the cavernous sinus were treated by means of external carotid artery (ECA) embolization using polyvinyl alcohol. All AVMs received vascular supply from both the ECA and the internal carotid artery. Seven cases were clinically cured after embolization, while 2 cases with cortical venous drainage and high flow through the shunt were not completely cured. Venous thrombosis was observed in 5 cases before and in 9 after embolization. In 6 cases the drainage pattern changed owing to venous thrombosis. Complete thrombosis of the cavernous sinus was found on a follow-up angiography in 2 cases. Formation of venous thrombosis and occlusion of feeding arteries are curcial factors for success of ECA embolization. Dural AVMs with cortical venous drainage and high flow cannot be relieved by ECA embolization alone owing to difficulty in obtaining thrombosis of the veins. (orig.)

  17. Magnetic resonance imaging of a cerebral cavernous haemangioma in a dog : clinical communication

    Directory of Open Access Journals (Sweden)

    J.P. Schoeman

    2002-07-01

    Full Text Available A 13-month-old, neutered, male Golden retriever presented with seizures and progressive depression. Clinical and neurological assessment was consistent with severe intracranial disease. The neurological condition progressively deteriorated and magnetic resonance imaging (MRI revealed the presence of a large, contrast-enhancing, space-occupying mass in the right cerebral hemisphere. Therapy with corticosteroids, mannitol and furosemide ameliorated the signs of depression and ataxia, but the owner elected euthanasia after 1 week. Post mortem examination of the brain confirmed the presence of a large haemorrhagic lesion in the right olfactory lobe, the histopathological appearance of which was consistent with cerebral cavernous haemangioma. This is the 1st case describing the MRI appearance of a cavernous haemangioma of the cerebrum in the veterinary literature.

  18. Design of a novel Cherenkov detectors system for machine induced background monitoring in the CMS cavern

    CERN Document Server

    Orfanelli, Styliani; Giunta, Marina; Stickland, David P; Ambrose, Mitchell J; Rusack, Roger; Finkel, Alexey

    2013-01-01

    A novel detector system has been designed for an efficient online measurement of the machineinduced background in the CMS experimental cavern. The suppression of the CMS cavern background originating from pp collision products and the 25 ns bunch spacing have set the requirements for the detector design. Each detector unit will be a radiation hard, cylindrical Cherenkov radiator optically coupled to an ultra-fast UV-sensitive photomultiplier tube, providing a prompt, directionally sensitive measurement. Simulation and test beam measurements have shown the achievability of the goals that have driven the baseline design. The system will consist of 20 azimuthally distributed detectors per end, installed at a radius of r ~ 180 cm and a distance 20.6 m away from the CMS interaction region. The detector units will enable a measurement of the transverse distribution of the bunchby- bunch machine induced background flux. This will provide important feedback from the CMS on the beam conditions during the LHC machine s...

  19. Bipolar radiofrequency ablation for symptomatic giant (>10 cm) hepatic cavernous haemangiomas: Initial clinical experience

    International Nuclear Information System (INIS)

    Aim: To describe initial clinical experience with bipolar radiofrequency ablation (RFA) for symptomatic giant hepatic haemangiomas. Materials and methods: Four consecutive patients with a large-volume, symptomatic hepatic cavernous haemangioma of >10 cm were treated with bipolar RFA during laparotomy with ultrasound guidance. Complications were carefully noted. Clinical and radiological effectiveness were evaluated comparing baseline with 3 and 6 months follow-up of symptom assessments and upper abdominal magnetic resonance imaging (MRI) or computed tomography (CT). Results: RFA was successfully performed for all four giant haemangiomas. No major complications were observed. Peri-procedural shrinking was remarkable and intermediate-term volume reduction ranged from 58–92% after 6 months. Symptom relief after 6 months was complete in two patients and considerable in the other two. Conclusion: Preliminary results suggest intra-operative bipolar RFA to be a safe, feasible, and effective technique for treatment of giant symptomatic hepatic cavernous haemangiomas.

  20. Design and construction of the tensioned ties for UX15 cavern vault

    CERN Document Server

    Parkin, R J H

    2002-01-01

    Due to the programme constraints for the UX15 cavern set by CERN, it has been necessary to complete the concrete lining of the vault prior to the excavation of the bench. The vault lining is therefore being temporarily suspended from a number of pre-tensioned high capacity multi-strand tensioned ties. During excavation of the bench, additional loads will be imposed onto the vault lining due to ground displacements. In order to minimise the number of ties, the previously completed linings of the PX14 and PX16 access shafts will be used to support some of the load. Three-dimensional modelling has been undertaken to design the structures and determine the expected behaviour of this complex support system. Geotechnical instrumentation has been installed in the concrete linings and the ground to monitor loads and displacements during construction. After the cavern walls have been completed, the ties will be released.

  1. Cerebral Hemorrhage after Endovascular Treatment of Bilateral Traumatic Carotid Cavernous Fistulae with Covered Stents

    OpenAIRE

    Cho, Kwang-Chun; Seo, Dae-Hee; Choe, Il-Seung; Park, Sung-Choon

    2011-01-01

    Bilateral traumatic carotid-cavernous fistulae (TCCFs) is rarely encountered neurovascular disease. For treatment of TCCF, detachable balloons have been widely used. Nowadays, transarterial and/or transvenous coil embolization with placement of covered stents is adopted as another treatment method. We experienced a patient with a bilateral TCCFs who was successfully treated with covered stents. However, cerebral hemorrhage occurred in the bed of previous infarction one day after treatment. Hy...

  2. A cavernous haemangioma of breast in male: radiological-pathological correlation

    Energy Technology Data Exchange (ETDEWEB)

    Carreira, C.; Romero, C.; Urbasos, M.; Pinto, J. [Servicio de Radiologia, Hospital ' ' Virgen de la Salud' ' , Toledo (Spain); Rodriguez, R.; Francisco, J.M. de [Servicio de Anatomia Patologica, Hospital ' ' Virgen de la Salud' ' , Toledo (Spain)

    2001-02-01

    Vascular tumours of the breast are especially rare in men, and a majority of them are angiosarcomas. In fact, we found only four cases of haemangioma in males in the literature. We present a case of cavernous haemangioma in a male aged 48 years, and which commenced as a palpable mass. We performed differential diagnosis and radiological-pathological correlation. We established the correct classification of this case histologically, and decided on the definitive therapeutic approach. (orig.)

  3. First DT+RPC chambers installation round in the UX5 cavern

    CERN Multimedia

    Jesus Puerta-Pelayo

    2007-01-01

    DT+RPC packages corresponding to sectors 1 and 7 of the barrel region cannot be installed on surface, since the lowering gantry from SX5 to UX5 uses their gaps to hold the wheels. Therefore this installation has to be carried out in the cavern. These pictures illustrate the first installation round on YB+2 right after the lowering. A total of 8 chambers were successfully installed in 2 days.

  4. Phenotypic modulation of corpus cavernosum smooth muscle cells in a rat model of cavernous neurectomy.

    Directory of Open Access Journals (Sweden)

    Fan Yang

    Full Text Available Patients undergoing radical prostatectomy (RP are at high risk for erectile dysfunction (ED due to potential cavernous nerve (CN damage during surgery. Penile hypoxia after RP is thought to significantly contribute to ED pathogenesis.We previously showed that corpora cavernosum smooth muscle cells (CCSMCs undergo phenotypic modulation under hypoxic conditions in vitro. Here, we studied such changes in an in vivo post-RP ED model by investigating CCSMCs in bilateral cavernous neurectomy (BCN rats.Sprague-Dawley rats underwent sham (n = 12 or BCN (n = 12 surgery. After 12 weeks, they were injected with apomorphine to determine erectile function. The penile tissues were harvested and assessed for fibrosis using Masson trichrome staining and for molecular markers of phenotypic modulation using immunohistochemistry and western blotting. CCSMC morphological structure was evaluated by hematoxylin-eosin (H&E staining and transmission electron microscopy (TEM.Erectile function was significantly lower in BCN rats than in sham rats. BCN increased hypoxia-inducible factor-1α and collagen protein expression in corpora cavernous tissue. H&E staining and TEM showed that CCSMCs in BCN rats underwent hypertrophy and showed rough endoplasmic reticulum formation. The expression of CCSMC phenotypic markers, such as smooth muscle α-actin, smooth muscle myosin heavy chain, and desmin, was markedly lower, whereas vimentin protein expression was significantly higher in BCN rats than in control rats.CCSMCs undergo phenotype modulation in rats with cavernous neurectomy. The results have unveiled physiological transformations that occur at the cellular and molecular levels and have helped characterize CN injury-induced ED.

  5. Diffuse Cavernous Hemangioma of the Penis, Scrotum, Perineum, and Rectum - A rare tumor

    Directory of Open Access Journals (Sweden)

    Rastogi Rajul

    2008-01-01

    Full Text Available Hemangiomas are benign lesions that occur in any part of the body. Genital hemangioma involving the entire penis and scrotum are extremely rare. More rarely they can extend in to the pelvis making preoperative imaging imperative and decisive in treatment. Very few cases have been reported in the medical literature. Hereby, a rare cavernous hemangioma that involves the entire penis, scrotum and extends into perineum and rectum in an 18-year-old male is presented with review of literature.

  6. Diffuse Cavernous Hemangioma of the Penis, Scrotum, Perineum, and Rectum - A rare tumor

    OpenAIRE

    Rastogi Rajul

    2008-01-01

    Hemangiomas are benign lesions that occur in any part of the body. Genital hemangioma involving the entire penis and scrotum are extremely rare. More rarely they can extend in to the pelvis making preoperative imaging imperative and decisive in treatment. Very few cases have been reported in the medical literature. Hereby, a rare cavernous hemangioma that involves the entire penis, scrotum and extends into perineum and rectum in an 18-year-old male is presented with review of literature.

  7. Cavernous mesenteric lymphangiomatosis mimicking metastasis in a patient with rectal cancer: A case report

    Institute of Scientific and Technical Information of China (English)

    Seong Su Hwang; Hyun Joo Choi; Soo Youn Park

    2009-01-01

    Lymphangioma usually occurs in children and usually involves the skin. Mesenteric lymphangioma is extremely rare in adults. Typically, lymphangioma appears on computed tomography (CT) as a lower attenuation of a cystic mass, however, some cases appear to be a solid mass. We describe the CT and 18FFDG positron emission tomography/CT appearance in a case of jejunal and mesenteric cavernous lymphangiomatosis mimicking metastasis in an adult patient with rectal cancer.

  8. Sudden onset proptosis secondary to cavernous sinus thrombosis from underlying mandibular dental infection

    OpenAIRE

    Jones, Robin Gwynne; Arnold, Brendan

    2009-01-01

    The present report concerns a patient who presented with a 4-day history of left-sided facial pain arising from a pre-existing dental infection and progressive shortness of breath. The patient had a previous diagnosis of rheumatoid arthritis and was being treated with methotrexate. The rapid development of a right eye proptosis necessitated urgent decompression with a lateral canthotomy and cantholysis. Imaging revealed a left facial abscess, cavernous sinus thrombosis (CST), bilateral intern...

  9. Current status of the demonstration test of underground cavern-type disposal facilities

    International Nuclear Information System (INIS)

    In Japan, the underground cavern-type disposal facilities for low-level waste (LLW) with relatively high radioactivity, mainly generated from power reactor decommissioning, and for certain transuranic (TRU) waste, mainly from spent fuel reprocessing, are designed to be constructed in a cavern 50-100 m underground and to employ an engineered barrier system (EBS) made of bentonite and cement materials. To advance a disposal feasibility study, the Japanese government commissioned the Demonstration Test of Underground Cavern-Type Disposal Facilities in fiscal year (FY) 2005. Construction of a full-scale mock-up test facility in an actual subsurface environment started in FY 2007. The main test objective is to establish the construction methodology and procedures that ensure the required quality of the EBS on-site. A portion of the facility was constructed by 2010, and the test has demonstrated both the practicability of the construction and the achievement of quality standards: low permeability of less than 5x10-13 m/s and low-diffusion of less than 1x10-12 m2/s at the completion of construction. This paper covers the test results from the construction of certain parts using bentonite and cement materials. (author)

  10. Rhino-orbitocerebral mucormycosis associated with cavernous sinus thrombosis: case report

    Directory of Open Access Journals (Sweden)

    Haber, Daniel Martiniano

    2008-12-01

    Full Text Available Introduction: Mucormycosis is a rare opportunistic infection caused by Mucorales fungi, and the Rhizopus is the most common one (70% of the cases. It is an acute invasive fungal disease whose form is disseminated, cutaneous, pulmonary, gastrointestinal and rhino-orbitocerebral. The latter is the most common form and its symptoms comprise of unilateral sinusitis, fever and headache. Once established in the orbit the symptoms can be chemosis, diplopia and reduced vision. The infection can spread to the brain via the orbital apex, orbital arteries or via the cribriform plate. Mucormycosis is a medical emergency and the treatment consists of a surgery to an aggressive debridement and in the use of antifungal therapy. Despite the appropriate management, the mortality rate can reach 40% of the cases. One possible intracranial complication of Mucormycosis is the Cavernous Sinus Thrombosis which is a rare and fatal infective disease. The initial symptoms of Cavernous Sinus Thrombosis are headache, retro-orbital pain, periorbital edema, proptosis, diplopia and reduced vision. Case Report: We describe the case of 43-year-old woman with medical history of diabetes mellitus and use of immunosuppressant drugs after kidney transplantation. The patient developed Acute Bacterial Sinusitis and Rhino-orbitocerebral Mucormycosis associated with Cavernous Sinus Thrombosis.

  11. Superselective embolization with Pingyangmycin lipiodol emulsion for the treatment of liver cavernous hemangioma

    International Nuclear Information System (INIS)

    Objective: To evaluate the advantages and disadvantages of super selective embolization therapy with Pingyangmycin lipiodol emulsion in treating liver cavernous hemangiomas. Methods: One hundred and fifty patients with hepatic cavernous hemangioma underwent super selective hepatic artery embolization treatment with Pingyangmycin lipiodol emulsion. The changes of clinic symptoms and tumor volumes, and the occurrence of complications were observed both before treatment and at 3 and 6 months after treatment. Results: CT scans showed that the blood supply of the tumor disappeared at 3 months and 6 months after treatment, and tumor volume was reduced in all patients. The lipiodol deposited well within the tumor in all patients. The mean tumor diameter was (8.47 ± 2.2 7) cm before intervention, which decreased to (5.75 ± 1.40) cm (P < 0.05) at 6 months after treatment and to (3.51 ± 0.82) cm at 12 months after treatment. The clinic symptoms were alleviated or even disappeared in all patients. No severe complications such as gallbladder injury, bile duct stenosis or hepatic necrosis occurred during and after the therapy. Conclusion: Super selective embolization therapy with Pingyangmycin lipiodol emulsion is an effective, safe and minimally-invasive non-surgical treatment for liver cavernous hemangiomas. With satisfactory clinical results, this technique can be regarded as an ideal embolization therapy. (authors)

  12. Simulation of concrete deterioration in Finnish rock cavern conditions for final disposal of nuclear waste

    International Nuclear Information System (INIS)

    Highlights: • Concrete deterioration in Finnish rock cavern disposal conditions was simulated. • Simulation requires advanced models instead of traditional linear diffusion models. • Concrete analysed performed moderately during the period of 500 years. • Corrosion of steel reinforcement cannot be excluded during the period analysed. - Abstract: A simulation of concrete ageing in Finnish rock cavern disposal conditions showed that the concrete undergoes complex deterioration processes during the period required for lowering the level of radiation. In respect of the concrete ageing, the life time of the disposal facilities shall be divided into the periods before and after the closing of the caverns. Generally, the sulphate-resistant type of concrete analysed performed moderately during the analysed period of 500 years contrary to the corrosion of steel reinforcement, which cannot be excluded. Simulation of ageing clearly requires thermodynamical methods instead of linear diffusion models based on Fick’s law, which are traditionally used in construction industry. The study proves that the thermodynamical simulation method developed with adequate experimental data also makes it possible to observe latent factors of concrete deterioration

  13. Pregnancy and cavernous sinus syndrome in diffuse large B-cell lymphoma

    Directory of Open Access Journals (Sweden)

    Juan Wang

    2013-01-01

    Full Text Available Diffuse large B-cell lymphoma (DLBCL usually present with rapidly growing lymph nodes or extra-nodal masses. Central nerve system involvement and pregnancy are rare in DLBCL. Here, we report an unusual case of DLBCL with cavernous sinus syndrome during pregnancy. A 24-year-old woman presented cavernous sinus syndrome as the initial presentation during pregnancy. Magnetic resonance imaging (MRI revealed enlargement of bilateral cavernous sinus. Tonsil and ovary biopsy indicated malignant lymphoma-DLBCL. Bone marrow smear showed infiltration by tumor cells. The case delivered a viable baby by cesarean section and then took chemotherapy of rituxan, cyclophosphamide, adriamycin, eldisine and dexamethasone. The disease deteriorated rapidly, especially after the pregnancy was terminated. Fortunately, a complete response was achieved after six cycles of chemotherapy. With the accumulation of clinical practice of such cases, we would be able to recognize minimal symptoms of DLBCL at the beginning and confirm the most suitable timing of the initiation of chemotherapy during pregnancy.

  14. Current status of the Demonstration Test of Underground Cavern-Type Disposal Facilities

    International Nuclear Information System (INIS)

    In Japan, the underground cavern-type disposal facilities for low-level waste (LLW) with relatively high radioactivity, mainly generated from power reactor decommissioning, and for certain transuranic (TRU) waste, mainly from spent fuel reprocessing, are designed to be constructed in a cavern 50-100 m underground and to employ an engineered barrier system (EBS) made of bentonite and cement materials. To advance a disposal feasibility study, the Japanese government commissioned the Demonstration Test of Underground Cavern-Type Disposal Facilities in fiscal year (FY) 2005. Construction of a full-scale mock-up test facility in an actual subsurface environment started in FY 2007. The main test objective is to establish the construction methodology and procedures that ensure the required quality of the EBS on-site. A portion of the facility was constructed by 2010, and the test has demonstrated both the practicability of the construction and the achievement of quality standards: low permeability of less than 5x10-13 m/s and low-diffusion of less than 1x10-12 m2/s at the completion of construction. This paper covers the test results from the construction of certain parts using bentonite and cement materials. (author)

  15. Failure Monitoring and Leakage Detection for Underground Storage of Compressed Air Energy in Lined Rock Caverns

    Science.gov (United States)

    Kim, Hyung-Mok; Rutqvist, Jonny; Kim, Hyunwoo; Park, Dohyun; Ryu, Dong-Woo; Park, Eui-Seob

    2016-02-01

    Underground compressed air energy storage (CAES) in lined rock caverns (LRCs) provides a promising solution for storing energy on a large scale. One of the essential issues facing underground CAES implementation is the risk of air leakage from the storage caverns. Compressed air may leak through an initial defect in the inner containment liner, such as imperfect welds and construction joints, or through structurally damaged points of the liner during CAES operation for repeated compression and decompression cycles. Detection of the air leakage and identification of the leakage location around the underground storage cavern are required. In this study, we analyzed the displacement (or strain) monitoring method to detect the mechanical failure of liners that provides major pathways of air leakage using a previously developed numerical technique simulating the coupled thermodynamic and geomechanical behavior of underground CAES in LRCs. We analyzed the use of pressure monitoring to detect air leakage and characterize the leakage location. From the simulation results, we demonstrated that tangential strain monitoring at the inner face of sealing liners could enable one to detect failure. We also demonstrated that the use of the cross-correlation method between pressure history data measured at various sensors could identify the air leak location. These results may help in the overall design of a monitoring and alarm system for the successful implementation and operation of CAES in LRCs.

  16. Coil embolization of cavernous sinus in patients with direct and dural arteriovenous fistula

    Energy Technology Data Exchange (ETDEWEB)

    Bink, Andrea; Berkefeld, Joachim; Zanella, Friedhelm; Mesnil de Rochemont, Richard du [Goethe University, Department of Neuroradiology, Frankfurt am Main (Germany); Luechtenberg, Marc [Goethe University, Department of Ophthalmology, Frankfurt/Main (Germany); Gerlach, Ruediger [Goethe University, Department of Neurosurgery, Frankfurt/Main (Germany); Neumann-Haefelin, Tobias [Goethe University, Department of Neurology, Frankfurt/Main (Germany)

    2009-06-15

    To determine technical success and acute complication rates after endovascular coil packing of the cavernous sinus. Nineteen patients presented with either direct (13) or dural (6) arteriovenous fistula (AVF) and were treated by means of coil embolization of the cavernous sinus. The aim of treatment was complete obliteration of the fistula. In a retrospective study, the degree of obliteration, regression of symptoms as well as complication rates were evaluated. Initial complete obliteration was achieved in 12 patients, subtotal occlusion of the sinus in 6 and incomplete packing with major residual fistula in 1 of the patients. Retreatment was successfully performed in two patients with early recurrence of AVF. Follow-up showed complete occlusion rates in 16 and subtotal obliteration in 3 patients. Chemosis and exophthalmus regressed rapidly in all affected patients. Persistence of cranial nerve deficits was observed in 11 cases. Postinterventional thrombosis of the ophthalmic vein was the only major acute complication (n = 2). Coil embolization of the cavernous sinus in cases with AVF is a complex procedure that is technically feasible and safe in the majority of cases. Adequate anticoagulation is recommended to avoid thrombembolic complications. Long-term outcome has to be determined by further studies. (orig.)

  17. Coil embolization of cavernous sinus in patients with direct and dural arteriovenous fistula

    International Nuclear Information System (INIS)

    To determine technical success and acute complication rates after endovascular coil packing of the cavernous sinus. Nineteen patients presented with either direct (13) or dural (6) arteriovenous fistula (AVF) and were treated by means of coil embolization of the cavernous sinus. The aim of treatment was complete obliteration of the fistula. In a retrospective study, the degree of obliteration, regression of symptoms as well as complication rates were evaluated. Initial complete obliteration was achieved in 12 patients, subtotal occlusion of the sinus in 6 and incomplete packing with major residual fistula in 1 of the patients. Retreatment was successfully performed in two patients with early recurrence of AVF. Follow-up showed complete occlusion rates in 16 and subtotal obliteration in 3 patients. Chemosis and exophthalmus regressed rapidly in all affected patients. Persistence of cranial nerve deficits was observed in 11 cases. Postinterventional thrombosis of the ophthalmic vein was the only major acute complication (n = 2). Coil embolization of the cavernous sinus in cases with AVF is a complex procedure that is technically feasible and safe in the majority of cases. Adequate anticoagulation is recommended to avoid thrombembolic complications. Long-term outcome has to be determined by further studies. (orig.)

  18. Evaluation of Computational Method of High Reynolds Number Slurry Flow for Caverns Backfilling

    Energy Technology Data Exchange (ETDEWEB)

    Bettin, Giorgia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-05-01

    The abandonment of salt caverns used for brining or product storage poses a significant environmental and economic risk. Risk mitigation can in part be address ed by the process of backfilling which can improve the cavern geomechanical stability and reduce the risk o f fluid loss to the environment. This study evaluate s a currently available computational tool , Barracuda, to simulate such process es as slurry flow at high Reynolds number with high particle loading . Using Barracuda software, a parametric sequence of simu lations evaluated slurry flow at Re ynolds number up to 15000 and loading up to 25%. Li mitations come into the long time required to run these simulation s due in particular to the mesh size requirement at the jet nozzle. This study has found that slurry - jet width and centerline velocities are functions of Re ynold s number and volume fractio n The solid phase was found to spread less than the water - phase with a spreading rate smaller than 1 , dependent on the volume fraction. Particle size distribution does seem to have a large influence on the jet flow development. This study constitutes a first step to understand the behavior of highly loaded slurries and their ultimate application to cavern backfilling.

  19. Resection of Giant Hepatic Cavernous Hemangiomas after Dissection of the Third Porta Hepatis

    Institute of Scientific and Technical Information of China (English)

    YAOXiaoping; ZHOUWeiping; WANGYi; WUMengchao; JINGLiang

    2002-01-01

    Objective:To estabhsh a novel and safe operation technique for the resection of giant hepatic cavernous hemangiomas involving the retro-hepatic vena cava.Methods:After ligating the hepatic artery of affected lobe, the short hepatic veins at the third porta hepatis were dissected and ligated individually to separate the tumor from the retrohepatic vena cava, followed by the resection of the tumor under intermittent interruption of the porta hepatis.Results:A total of 62 giant hepatic cavernous hemangiomas were successfully resected without hepatic vascular exclusion. Right and caudate lobectomies were done in 27 cases, right hemihepatectornies in 5 cases, right upper segnentectomies in 7 cases, right posterior lobectomies in 7 cases, extended left and caudate lobectomies in 10 cases, and caudate lobectomies in 6 cases. The blood transfusion requirement during operation was 1 400 ml on average. All did well postoperatively during a follow up of 4 - 84 months.Conclusion:It is safe and feasible to resect giant hepatic cavernous hemangioma following dissection of the third porta hepatis. Duringoperation the key step is dissection of the short hepatic veins.

  20. Helical CT finding of carotid-cavernous fistula: a sign of early enhancing superior ophthalmic vein

    International Nuclear Information System (INIS)

    The purpose of this study was to determine the diagnostic value of a sign of early enhancing superior ophthalmic vein (SOV), as seen on helical CT images in patients with carotid-cavernous fistula (CCF). This study involved 16 patients with CCF and 28 control patients. Axial CT images with scanning delays of 30 seconds following bolus injection of contrast material (90 mL, 3 mL/sec) were obtained, and this procedure was followed by coronal CT imaging. To determine the presence or absence of early enhancement or, dilatation of the SOV, bulging of the cavernous sinus, and enlargement of extraocular muscle, CT images were analysed by three observers in a blinded, random manner. Early enhancement of SOV was determined to be present where enhancement of the SOV was similar to or stronger than that of the ipsilateral posterior cerebral artery. A sign of early enhancing SOV was seen in 14 of the 16 patients with CCF but in no control patients (88% sensitivity and 100% specificity). The respective sensitivity and specificity of other CT features were 71% and 100% (dilatation of the SOV, as seen on axial images), 60% and 83% (dilatation of the SOV, as seen on coronal images), 71% and 89% (dilatation of the cavernous sinus), and 65% and 98% (enlargement of extraocular muscle). A sign of early enhancing SOV is a characteristic and specific CT finding of CCF, and is useful for the diagnosis of CCF. (author)

  1. Superior ophthalmic vein approach for endovascular treatment of dural cavernous sinus fistulas

    International Nuclear Information System (INIS)

    Objective: To investigate the method for surgical exposure the superior ophthalmic vein with embolization of the cavernous sinus dural arteriovenous fistula and evaluate its efficacy and safety. Methods: Surgical exposure of the superior ophthalmic vein was performed by eyelid incision and followed by catheterization and embolization with micro-coils for 16 patients with cavernous sinus dural arteriovenous fistulas. Results: Clinical cure was achieved in all patients and complete angiographic obliteration of fistula was documented in 15 patients (94%). Residual fistula was left in 1 patients with compact occlusion via pterygoid drainage but disappeared one month later by manual compression of the carotid artery. Headache and vomiting were the most common symptoms after the embolization, other 2 patients had mild diplopia and relieved within two months. No permanent procedure-related morbidity and recurrence occurred during clinical follow up for 5 months to 6 years. Conclusion: Surgical exposure of the superior ophthalmic vein for embolization of cavernous sinus dural arteriovenous fistula is a safe and efficient method. (authors)

  2. Electrocorticography-Guided Surgical Treatment of Solitary Supratentorial Cavernous Malformations with Secondary Epilepsy

    Institute of Scientific and Technical Information of China (English)

    Chao Wang; Chao You; Guo-qiang Han; Jun Wang; Yun-biao Xiong; Chuang-xi Liu

    2014-01-01

    Objective To evaluate the efficacy of electrocorticographic (ECoG) monitoring and the application of different surgical approaches in the surgical treatment of solitary supretentorial cavernous malformations with secondary epilepsy. Methods This study enrolled a consecutive series of 36 patients with solitary supratentorial cavernous malformations and secondary epilepsy who underwent surgery with intraoperative ECoG monitoring in the Department of Neurosurgery between January 2004 and January 2008. The patients were composed of 15 males and 21 females, aged between 8 and 52 years (mean age 27.3±2.8 years) at the time of surgery. Epilepsy history, the type of epilepsy at the presentation, lesion location, the incidence of residual epileptiform discharges, and postoperative outcomes were evaluated. Results Histopathological examination indicated cavernous malformations and hippocampal sclerosis in 36 and 5 cases, respectively. Neuronal degeneration, glial cell proliferation, and neurofibrillary tangles were found in all the resected cerebral tissues of extended lesionectomy of residual epileptic foci. Lesionectomy, anterior temporal lobectomy, anterior temporal lobectomy plus cortical thermocoagulation, extended lesionectomy, extended lesionectomy plus cortical thermocoagulation were performed in 4, 4, 1, 14, and 13 cases, respectively. Residual epileptiform discharges were captured in 9 out of the 14 patients who had additional cortical thermocoagulation. According to Engle class for postoperative outcomes, 27 cases were class I (75.00%), 5 were class II (13.89%), 2 were class III (5.56%), and 2 were class IV (5.56%), thus the total effective rate (class I+class II) was 88.89%. Neither of epilepsy history, the type of epilepsy, and the location of cavernous malformation was significantly related to outcomes (P>0.05). A significant relationship was found between the incidence of residual epileptiform discharges and outcomes (P=0.041). Conclusions Intraoperative ECo

  3. Annex 3: Determining the hydration heat data of a granulate/filler mixture filled into a 10 m3 model cavern

    International Nuclear Information System (INIS)

    One important aim of the model cavern experiments was a comparison of the measured product temperatures with the calculated time-and place-dependent temperature curves, from which conclusions can be drawn on the quality of temperature estimates for a large cavern. (orig./PW)

  4. Conceptual design of a large cavern for giant liquid argon charge imaging equipment in Oki-no-shima Island

    International Nuclear Information System (INIS)

    The T2K utilizing J-PARK high intensity started the data accumulation. If beam intensity of J-PARC will become the 1MW class in the future, we will build the cavern under the ground in Oki-no-shima to accommodate the experiment with 100kton liquid Ar TPC. Geologically, the Oki gneiss in the Oki-no-shima eastern side is very stable. The Oki gneiss is the one of the Japanese oldest rocks born about 2 billion years ago and compressive strength of the bedrock is about 80Mpa over. The development of the crack is not seen and has few springs in the underground. We designed large dome cylindrical cavern(the diameter 90m and the height 50m) for storage 100kton liquid Ar, some access tunnel and others connected to a cavern. (author)

  5. Transarterial embolization of dural carotid cavernous fistulas with low concentration of n-butyl-cyanoacrylate

    International Nuclear Information System (INIS)

    Objective: To investigate the technique of transarterial embolization of dural carotid- cavernous fistulas (DCCFs) with low concentration (14%-25%) of n-butyl-cyanoacrylate (NBCA) and determine its value. Methods: Eight patients with DCCFs were treated by transarterial embolization with low concentration of NBCA using a wedged microcatheter. Of the 8 patients, 5 had unsuccessful transvenous embolization and 3 could not be treated with transvenous embolization. Results: Transarterial embolization with low concentration of NBCA using a wedged microcatheter resulted in complete obliteration of the affected cavernous sinus and related shunts in 5 patients, no residual arteriovenous shunt was demonstrated on post- embolization angiography. On clinical and angiographic follow-up 6-12 months later, complete resolution of clinical symptoms was observed in all 5 patients and there were no recurrent or residual DCCFs found. Partial obliteration of the involved cavernous sinus and the related shunt was achieved in the remaining 3 patients on immediate post-procedure angiography, but the volume of shunt diminished significantly. On clinical and angiographic follow-up 3 months later, in 2 patients, clinical symptoms were improved and the arteriovenous shunts were diminished; in the third patient, clinical symptom resolved and the shunt was obliterated. There were no major complications except for the transient worsening of ocular symptoms due to VI cranial nerve palsy in 1 patient. Conclusions: Transarterial embolization of DCCFs with low concentration of NBCA using a wedged microcatheter was a safe and effective treatment method. It is an optimal alternative for the patients with DCCFs in which transvenous route was unsuccessful, or impossible. (authors)

  6. Preoperative irradiation of an extracerebral cavernous hemangioma in the middle fossa

    International Nuclear Information System (INIS)

    This is a report of case with the extracerebral cavernous hemangioma in the middle fossa in which total removal was carried out after radiotherapy. Follow-up study with computed tomography during and after irradiation are presented. A 44-year-old house-wife complained of a decreased vision of the both eyes and paresis of the left upper and lower limbs. CT scan revealed a slightly high density area in the right middle cranial fossa which was markedly enhanced with contrast media. Right carotid angio-graphy demonstrated a large avascular mass in the right middle fossa and no feeding artery or draining vein was visualized except a faint irregular stain in the venous phase. An attempt to total removal of the tumor had failed to success because of extensive hemorrhage from the tumor. Histological examination revealed a cavernous hemangioma. Irradiation with a total dose of 5000 rads was delivered. After irradiation. CT scan revealed a marked decrease of size and EMI number of the tumor. At this stage, hypervascular mass lesion with feeding arteries was noted in conventional angiography. Tumor stain in prolonged injection angiography was also visualized. In the second operation, removal of the tumor was performed without any difficulty and hemorrhage was controlled easily by electrocoagulation. Histology revealed a marked narrowing of vessels with an increase in the connective tissues. In the central part of specimen, there noted findings of coagulation necrosis, intraluminal thrombus formations and so on, which were attributed to the influence of radiation. It is concluded that in case of a extracerebral cavernous hemangioma with massive hemorrhage, radiation of up to 3000 - 5000 rads was a method of choice. The treatment results in an increase of probability of total removal of the tumor. (author)

  7. Fractionated external-beam radiation therapy for meningiomas of the cavernous sinus

    International Nuclear Information System (INIS)

    Purpose: Despite advances in microsurgical technique, many cavernous sinus meningiomas remain unresectable or only partially resectable, prompting referral of patients for radiation therapy. Stereotactic radiosurgery is recommended as therapy at some institutions. We evaluated our experience with fractionated radiotherapy to permit comparison with single-fraction radiosurgery. Materials and Methods: Between July 1985 and January 1998, 21 women and 7 men were treated for primary (21) or recurrent (7) cavernous sinus meningiomas. Of these, 22 tumors were subtotally resected and 6 were unresectable. Of the 28 lesions, 26 were categorized histologically as benign (16), aggressive-benign (7), or malignant (3); 2 were not biopsied. All patients were treated with fractionated photon irradiation to a median dose of 53.1 Gy. We assessed prognostic factors for overall (OS) and progression-free survival (PFS), including age, gender, presentation (primary vs. recurrent), extent of surgical resection, radiotherapy dose, and technique. Influence of radiotherapy dose and technique on acute and late treatment toxicities was analyzed. Results: One patient died of disease and 2 others were alive with progressive disease at last follow-up, yielding 8-year actuarial OS and PFS of 96% and 81%, respectively. Univariate analysis showed that none of the prognostic factors tested was significantly associated with OS or PFS. There were two late side effects of treatment: an orbital sac fibrosis and a 6-month decline of cognitive function documented by formal neuropsychiatric testing. Neither radiotherapy dose nor technique significantly influenced late toxicity. Conclusion: For unresectable or subtotally resected cavernous sinus meningiomas, fractionated radiotherapy provides patients with excellent progression-free survival and minimal treatment-related toxicity

  8. Pancreatic portal cavernoma in patients with cavernous transformation of the portal vein: MR findings

    Energy Technology Data Exchange (ETDEWEB)

    Vilgrain, Valerie [Universite Paris 7 Denis Diderot, Paris (France); AP-HP, Hopital Beaujon, Department of Radiology, Clichy (France); INSERM, Centre de recherche Biomedicale Bichat-beaujon, CRB3, Paris (France); Hopital Beaujon, Department of Radiology, Paris (France); Condat, Bertrand; Plessier, Aurelie [AP-HP, Hopital Beaujon, Department of Gastroenterology, Clichy (France); O' Toole, Dermot [Centre de reference des maladies vasculaires du foie, AP-HP, Hopital Beaujon, Department of Hepatology, PMAD, Clichy (France); Ruszniewski, Philippe [Universite Paris 7 Denis Diderot, Paris (France); INSERM, Centre de recherche Biomedicale Bichat-beaujon, CRB3, Paris (France); Centre de reference des maladies vasculaires du foie, AP-HP, Hopital Beaujon, Department of Hepatology, PMAD, Clichy (France); Valla, Dominique C. [Universite Paris 7 Denis Diderot, Paris (France); INSERM, Centre de recherche Biomedicale Bichat-beaujon, CRB3, Paris (France); AP-HP, Hopital Beaujon, Department of Gastroenterology, Clichy (France)

    2009-11-15

    The purpose of the article was to prospectively evaluate the MR findings of pancreatic portal cavernoma in a consecutive series of patients with cavernous transformation of the portal vein. This study was approved by the review board of our institution, and informed consent was obtained. The clinical and biological data and the MR imaging for 20 patients (11 female, 9 male; median age, 49 years) with cavernous transformation of the portal vein and no evidence of previous pancreatic disease were reviewed. The presence of pancreatic portal cavernoma (defined as intra- and/or peripancreatic portal cavernoma), morphological changes in the pancreas, biliary and ductal pancreatic abnormalities, and extension of the portal venous thrombosis were qualitatively assessed. Fifteen patients (75%) had pancreatic portal cavernoma with collateral formation in the pancreas and/or collaterals around the pancreas seen on dynamic contrast-enhanced MR sequences: three patients had both intra- and peripancreatic portal cavernoma, six had intrapancreatic portal cavernoma alone and six had peripancreatic portal cavernoma only. The presence of intra- or peripancreatic portal cavernoma was significantly associated with extension of the thrombosis to the splenic and superior mesenteric veins (p = 0.05). Morphological changes in the pancreas, heterogeneity on T2-weighted sequences and main ductal pancreatic abnormalities were seen in two, four and two patients, respectively. All these patients had intrapancreatic portal cavernoma. Bile duct dilatation was observed in 13 (65%) patients: among them three had extrahepatic dilatation only and these three patients had associated intrapancreatic portal cavernoma. In patients with cavernous transformation of the portal vein, intra- or peripancreatic portal cavernoma is common. In conclusion, intra- or peripancreatic portal cavernoma was only observed in patients with extension of the thrombosis to the splenic vein and/or the superior mesenteric

  9. Pancreatic portal cavernoma in patients with cavernous transformation of the portal vein: MR findings

    International Nuclear Information System (INIS)

    The purpose of the article was to prospectively evaluate the MR findings of pancreatic portal cavernoma in a consecutive series of patients with cavernous transformation of the portal vein. This study was approved by the review board of our institution, and informed consent was obtained. The clinical and biological data and the MR imaging for 20 patients (11 female, 9 male; median age, 49 years) with cavernous transformation of the portal vein and no evidence of previous pancreatic disease were reviewed. The presence of pancreatic portal cavernoma (defined as intra- and/or peripancreatic portal cavernoma), morphological changes in the pancreas, biliary and ductal pancreatic abnormalities, and extension of the portal venous thrombosis were qualitatively assessed. Fifteen patients (75%) had pancreatic portal cavernoma with collateral formation in the pancreas and/or collaterals around the pancreas seen on dynamic contrast-enhanced MR sequences: three patients had both intra- and peripancreatic portal cavernoma, six had intrapancreatic portal cavernoma alone and six had peripancreatic portal cavernoma only. The presence of intra- or peripancreatic portal cavernoma was significantly associated with extension of the thrombosis to the splenic and superior mesenteric veins (p = 0.05). Morphological changes in the pancreas, heterogeneity on T2-weighted sequences and main ductal pancreatic abnormalities were seen in two, four and two patients, respectively. All these patients had intrapancreatic portal cavernoma. Bile duct dilatation was observed in 13 (65%) patients: among them three had extrahepatic dilatation only and these three patients had associated intrapancreatic portal cavernoma. In patients with cavernous transformation of the portal vein, intra- or peripancreatic portal cavernoma is common. In conclusion, intra- or peripancreatic portal cavernoma was only observed in patients with extension of the thrombosis to the splenic vein and/or the superior mesenteric

  10. Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.

    Science.gov (United States)

    Wang, Junwen; Voellger, Benjamin; Benzel, Julia; Schlomann, Uwe; Nimsky, Christopher; Bartsch, Jörg W; Carl, Barbara

    2016-09-15

    Invasion of tumor cells critically depends on cell-cell or cell-extracellular matrix interactions. Enzymes capable of modulating these interactions belong to the proteinase families of ADAM (a disintegrin and metalloprotease) and MMP (matrix metalloprotease) proteins. Our objective is to examine their expression levels and evaluate the relationship between expression levels and cavernous sinus invasion in pituitary adenomas. Tissue samples from 35 patients with pituitary adenomas were analyzed. Quantitative real-time polymerase chain reaction (qPCR) was employed to assess mRNA expression levels for ADAM and MMP genes. Protein levels were examined using immunohistochemistry and Western Blot. Correlation analyses between expression levels and clinical parameters were performed. By silencing ADAM12 and MMP-14 with siRNA in a mouse pituitary adenoma cell line (TtT/GF), their cellular effects were investigated. In our study, nine women and 26 men were included, with a mean age of 53.1 years (range 15-84 years) at the time of surgery. There were 19 cases with cavernous sinus invasion. The proteins ADAM12 and MMP-14 were significantly up-regulated in invasive adenomas compared to noninvasive adenomas. Both human isoforms of ADAM12 (ADAM12L and ADAM12s) were involved in tumor invasion; moreover, ADAM12L was found to correlate positively with Ki-67 proliferation index in pituitary adenomas. In TtT/GF pituitary adenoma cells, silencing of ADAM12 and MMP-14 significantly inhibited cell invasion and migration, respectively, whereas only silencing of ADAM12 suppressed cell proliferation. We conclude that ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas, which qualifies these proteins in diagnosis and therapy. PMID:27144841

  11. Effect of sildenafil in cavernous arteries of patients with erectile dysfunction

    Directory of Open Access Journals (Sweden)

    Joaquim A Claro

    2003-08-01

    Full Text Available INTRODUCTION: Sildenafil citrate is a type 5 phosphodiesterase inhibitor, which has demonstrated excellent results in the treatment of erectile dysfunction. The effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction has not been established yet. The objective of this study was to assess the effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction, following an intracavernous injection of alprostadil. MATERIALS AND METHODS: 29 male patients, with mean age of 53.8 years (32 to 75 years, were prospectively evaluated. The mean time with complaint of erectile dysfunction was 50.5 months (6 to 168 months. Each patient was his own control. Patients underwent a measurement of peak systolic velocity before and after use of sildenafil citrate associated with 5 micrograms of alprostadil, through ultrasonic velocitometry Knoll/MIDUS® system. In the interval between measurements, approximately 15 days, patients used 3 tablets of sildenafil at home with their partners. RESULTS: Using only 5 mcg of alprostadil, average peak systolic velocity was 23.9 cm/s, and when associated to 50 mg of sildenafil it was 24.8 cm/s. Despite the increase in the flow rate caused by sildenafil, the difference was not statistically significant, Zcalculated = - 0.695 NS (Wilcoxon test. Twenty one of the 29 patients (72.4% showed global improvement in sexual performance with the use of sildenafil citrate at home. There was not a statistically significant correlation between the global response to sildenafil citrate and the increase in the peak systolic velocity. CONCLUSION: We concluded that, even though the use of 50 mg of sildenafil citrate associated with 5 mcg of alprostadil provides an increase in the peak systolic velocity of the cavernous arteries, there was no statistic difference in relation to alprostadil alone. There was no correlation between the global response to sildenafil and the increase in

  12. Mechanical stability of a salt cavern submitted to rapid pressure variations: Application to the underground storage of natural gas, compressed air and hydrogen

    International Nuclear Information System (INIS)

    Salt caverns used for the underground storage of large volumes of natural gas are in high demand given the ever-increasing energy needs. The storage of renewable energy is also envisaged in these salt caverns for example, storage of compressed air and hydrogen mass storage. In both cases, salt caverns are more solicited than before because they are subject to rapid injection and withdrawal rates. These new operating modes raise new mechanical problems, illustrated in particular by sloughing, and falling of overhanging blocks at cavern wall. Indeed, to the purely mechanical stress related to changes in gas pressure variations, repeated dozens of degrees Celsius of temperature variation are superimposed; causes in particular during withdrawal, additional tensile stresses whom may lead to fractures at cavern wall; whose evolution could be dangerous. The mechanical behavior of rock salt is known: it is elasto-viscoplastic, nonlinear and highly thermo sensitive. The existing rock salt constitutive laws and failures and damages criteria have been used to analyze the behavior of caverns under the effects of these new loading. The study deals with the thermo mechanics of rocks and helps to analyze the effects of these new operations modes on the structural stability of salt caverns. The approach was to firstly design and validate a thermodynamic model of the behavior of gas in the cavern. This model was used to analyze blowout in gas salt cavern. Then, with the thermo mechanical coupling, to analyze the effects of rapid withdrawal, rapid injection and daily cycles on the structural stability of caverns. At the experimental level, we sought the optimal conditions to the occurrence and the development of cracks on a pastille and a block of rock salt. The creep behavior of rock salt specimens in triaxial extension also was analyzed. (author)

  13. Burkitt's lymphoma with bilateral cavernous sinus and mediastinal involvement in a child

    Energy Technology Data Exchange (ETDEWEB)

    Huisman, Thierry A.G.M.; Tschirch, Frank; Schneider, Jacques F.L.; Martin-Fiori, Ernst; Willi, Ulrich V. [Department of Radiology and Magnetic Resonance Imaging, University Children' s Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich (Switzerland); Niggli, Felix [Department of Paediatrics, University Children' s Hospital Zurich, Zurich (Switzerland)

    2003-10-01

    We report a 12-year-old boy who presented with incomplete right ophthalmoplegia, exophthalmos and headache. Initial CT and MRI revealed a mass in the right cavernous sinus. During tumour work-up, CT identified additional tumour within the mediastinum. Biopsy of the mediastinal lesion identified Burkitt's lymphoma. We report on this case because radiologists and clinicians should be alerted to identify sites of primary Burkitt's lymphoma outside of the central nervous system if clinical symptoms indicate, or imaging shows, CNS lesions. Primary CNS involvement in Burkitt's lymphoma is rare. (orig.)

  14. Cavernous hemangioma presenting as a right adnexal mass in a child.

    Science.gov (United States)

    Correa-Rivas, María S; Colón-González, Gloria; Lugo-Vicente, Humberto

    2003-09-01

    This is the case of an 11-year-old girl who presented with a right adnexal mass and vague abdominal symptoms since seven months prior to her hospital admission for surgery. CT-scan and sonographic images were those of a benign lesion, probably ovarian torsion or infarction. Serum tumoral markers were normal. A right salpingo-oophorectomy and appendectomy were performed. Pathology examination revealed a cavernous hemangioma of the ovary. The clinicopathologic presentation of this unusual benign ovarian tumor is discussed. PMID:14619460

  15. Huge Cavernous Hemangiomas Enveloping the Optic Nerve Successfully Removed by a Vertical Lid Split Orbitotomy

    Directory of Open Access Journals (Sweden)

    Jung-Hoon Yum

    2014-01-01

    Full Text Available A 63-year-old woman presented with a 15-year history of gradually increasing proptosis of right eye. Ocular examination revealed proptosis of 9 mm with decreased visual acuity in her right eye. CT scan showed a well-circumscribed and enhancing orbital mass filling almost the entire right orbit. The tumor occupied the superolateral, superomedial, and inferomedial intraconal space, enveloping the optic nerve. Complete excision of two large intraconal tumors was performed successfully via a vertical lid split orbitotomy. Histopathologic examination confirmed the diagnosis of cavernous hemangioma. There were no intraoperative or postoperative complications. The patient achieved a satisfactory cosmetic outcome 1 year after surgery.

  16. The First Result of Global Commissioning of the ATLAS Endcap Muon Trigger System in ATLAS Cavern

    CERN Document Server

    Sugimoto, T; Takahashi, Y; Tomoto, M; Fukunaga, C; Ikeno, M; Iwasaki, H; Nagano, K; Nozaki, M; Sasaki, O; Tanaka, S; Yasu, Y; Hasegawa, Y; Oshita, H; Takeshita, T; Nomachi, M; Sugaya, Y; Kubota, T; Ishino, M; Kanaya, N; Kawamoto, T; Kobayashi, T; Kuwabara, T; Nomoto, H; Sakamoto, H; Yamaguchi, T; Kadosaka, T; Kawagoe, K; Kiyamura, H; Kurashige, H; Niwa, T; Ochi, A; Omachi, C; Takeda, H; Lifshitz, R; Lupu, N; Bressler, S; Tarem, S; Kajomovitz, E; Ben Ami, S; Bahat Treidel, O; Benhammou, Ya; Etzion, E; Lellouch, D; Levinson, L; Mikenberg, G; Roich, A

    2007-01-01

    We report on the ATLAS commissioning run from the view point of the Thin Gap Chamber (TGC), which is the ATLAS end cap muon trigger detector. All the TGC sectors with on-detector electronics are going to be installed to the ATLAS cavern by the end of September 2007. To integrate all sub-detectors before the physics run starting from early 2008, the global commissioning run together with other sub-detectors has been performed from June 2007. We have evaluated the performance of the complete trigger chain of the TGC electronics and provide the trigger signal using cosmic-ray to the sub-systems in the global run environment.

  17. Congenital pial arteriovenous fistula in the temporal region draining into cavernous sinus: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Ziyin; Wang, Chaohua; Zhang, Changwei; Xie, Xiaodong [Dept. of Neurosurgery, West China Hospital of Sichuan University, Chengdu (China); Wang, Kun; Tang, Jianjian [Dept. of Neurosurgery, Affiliated Hospital of Hainan Medical College, Haikou (China)

    2013-06-15

    This report concerns a 4-month-old infant with progressive prominent and redness of his left eye since birth. This report concerns a 4-month-old infant with progressive prominent redness of his left eye since birth. Angiography revealed a congenital pial arteriovenous fistula between the temporal branch of the left posterior cerebral artery and left cavernous sinus through the sphenoparietal sinus, a condition not reported in the literature. The fistula was successfully occluded with two micro-coils by vertebrobasilar approach.

  18. Congenital pial arteriovenous fistula in the temporal region draining into cavernous sinus: A case report

    International Nuclear Information System (INIS)

    This report concerns a 4-month-old infant with progressive prominent and redness of his left eye since birth. This report concerns a 4-month-old infant with progressive prominent redness of his left eye since birth. Angiography revealed a congenital pial arteriovenous fistula between the temporal branch of the left posterior cerebral artery and left cavernous sinus through the sphenoparietal sinus, a condition not reported in the literature. The fistula was successfully occluded with two micro-coils by vertebrobasilar approach.

  19. The benign course of carotid-cavernous fistula in a child

    International Nuclear Information System (INIS)

    Carotid-cavernous fistulas (CCF) are reported very rarely in childhood and their clinical course and prognosis are uncertain. We report a 9-year-old boy presented with left eye swelling, neck pain and headache. The MRI findings suggested a CCF with enlarged left superior ophthalmic vein. Ocular Doppler ultrasonography revealed enlarged left superior ophthalmic vein, and arterialization of Doppler wave form. The cerebral angiogram showed normal anatomy. Control Doppler examination findings supported the diagnosis of closure of fistula. The clinical and radiological findings of this unusual presentation are discussed

  20. Interactive evolution concept for analyzing a rock salt cavern under cyclic thermo-mechanical loading

    Science.gov (United States)

    König, Diethard; Mahmoudi, Elham; Khaledi, Kavan; von Blumenthal, Achim; Schanz, Tom

    2016-04-01

    The excess electricity produced by renewable energy sources available during off-peak periods of consumption can be used e.g. to produce and compress hydrogen or to compress air. Afterwards the pressurized gas is stored in the rock salt cavities. During this process, thermo-mechanical cyclic loading is applied to the rock salt surrounding the cavern. Compared to the operation of conventional storage caverns in rock salt the frequencies of filling and discharging cycles and therefore the thermo-mechanical loading cycles are much higher, e.g. daily or weekly compared to seasonally or yearly. The stress strain behavior of rock salt as well as the deformation behavior and the stability of caverns in rock salt under such loading conditions are unknown. To overcome this, existing experimental studies have to be supplemented by exploring the behavior of rock salt under combined thermo-mechanical cyclic loading. Existing constitutive relations have to be extended to cover degradation of rock salt under thermo-mechanical cyclic loading. At least the complex system of a cavern in rock salt under these loading conditions has to be analyzed by numerical modeling taking into account the uncertainties due to limited access in large depth to investigate material composition and properties. An interactive evolution concept is presented to link the different components of such a study - experimental modeling, constitutive modeling and numerical modeling. A triaxial experimental setup is designed to characterize the cyclic thermo-mechanical behavior of rock salt. The imposed boundary conditions in the experimental setup are assumed to be similar to the stress state obtained from a full-scale numerical simulation. The computational model relies primarily on the governing constitutive model for predicting the behavior of rock salt cavity. Hence, a sophisticated elasto-viscoplastic creep constitutive model is developed to take into account the dilatancy and damage progress, as well as

  1. Burkitt's lymphoma with bilateral cavernous sinus and mediastinal involvement in a child

    International Nuclear Information System (INIS)

    We report a 12-year-old boy who presented with incomplete right ophthalmoplegia, exophthalmos and headache. Initial CT and MRI revealed a mass in the right cavernous sinus. During tumour work-up, CT identified additional tumour within the mediastinum. Biopsy of the mediastinal lesion identified Burkitt's lymphoma. We report on this case because radiologists and clinicians should be alerted to identify sites of primary Burkitt's lymphoma outside of the central nervous system if clinical symptoms indicate, or imaging shows, CNS lesions. Primary CNS involvement in Burkitt's lymphoma is rare. (orig.)

  2. Endoscopically diagnosed cavernous hemangioma in the deep small intestine: A case report

    Directory of Open Access Journals (Sweden)

    Hsin-Hung Chen

    2015-06-01

    Full Text Available We report a 27-year-old female with chronic iron deficiency anemia and unexplained fecal occult blood. Abdominal ultrasonography and computed tomography disclosed a possible endoluminal lesion in the small intestine. Single-balloon enteroscopy detected the target lesion in the proximal ileum. The lesion was a 2.5-cm submucosal tumor that was purple-red, soft, had a narrow base, and exhibited superficial telangiectasia. After endoscopic marking, the tumor was resected with minimally invasive laparoscopy. It was histologically confirmed as a cavernous hemangioma. In this report, we discuss the endoscopic characteristics, surgical and pathological assessment, and management strategy of hemangiomas in the small intestine.

  3. The first Inner Detector End-Cap is lowered into the cavern

    CERN Multimedia

    Heinz Pernegger

    The first Inner Detector End-Cap, containing both the SCT and TRT detectors, arriving down the access shaft on the A-side. . The Inner Detector End-Cap A approaching the installation platform. During the difficult phase of inserting the Inner Detector into the cryostat. On Thursday, May 24, the first Inner Detector end-cap, with both the TRT and SCT end-caps, was taken down to the pit. More pictures can be found on the transfer from SR1 to SX1 as well as the lowering into the cavern and reception on the platform which can also be seen as a slide show

  4. CT and MR imaging of cerebral cavernous angiomas. Scanographie et IRM des angiomes caverneux cerebraux

    Energy Technology Data Exchange (ETDEWEB)

    Silbermann, O.; Dietemann, J.L.; Tajahmady, T.; Jeung, M.Y.; Granel de Solignac, M.; Vouge, M.; Badoz, A.; Dosch, J.C. (Centre Hospitalier Regional Universitaire 67 - Strasbourg (FR)) (and others); Froideveaux, J.C.; Kiesmann, M.

    1991-01-01

    Computed tomography, then MRI, have completely changed the diagnostic approach of cavernous hemangiomas. The CT image of these vascular malformations may still be misleading, as the lesion usually is naturally hyperdense and often enhances with an iodine injection; the differential diagnosis with low-grade astrocytoma or oligodendroglioma may be difficult. MRI produces a more characteristic image by demonstrating the peripheral rim of hemosiderin and the hemorrhagic sequellae in the center of the lesion. On T1- as well as T2-weighted images, the center of the lesion is hyperintense, while its periphery is hypointense.

  5. Giant cavernous carotid aneurysm with spontaneous ipsilateral ICA occlusion: Report of 2 cases and review of literature

    Directory of Open Access Journals (Sweden)

    Savitr BV Sastri

    2013-01-01

    Full Text Available Giant aneurysms of the cavernous carotid artery are rare entities which present predominantly with features of compression of the adjacent neural structures, most commonly the III, IV, VI and V cranial nerves. Historically, treatment options included occlusion of the feeding vessel, direct surgery on the aneurysm, bypass procedures and in recent times, the use of endovascular devices. While intramural thrombus formation is commonly seen in giant aneurysms, we present 2 cases of giant cavernous aneurysms which on evaluation were found to have spontaneous occlusion of the feeding internal carotid artery secondary to thrombus formation, and review the available literature regarding the same.

  6. Carotid-cavernous fistula caused by rupture of persistent primitive trigeminal artery trunk aneurysm--case report.

    Science.gov (United States)

    Yoshida, Masahiro; Ezura, Masayuki; Mino, Masaki

    2011-01-01

    A 60-year-old female presented with a carotid-cavernous fistula (CCF) manifesting as left abducens nerve palsy. Left internal carotid digital subtraction angiography showed a persistent primitive trigeminal artery (PPTA) near the CCF. Super-selective angiography showed direct shunt flow between the PPTA trunk aneurysm and the left cavernous sinus. The aneurysm was successfully occluded with detachable coils. The CCF disappeared and the PPTA was preserved. The abducens nerve paralysis had disappeared 6 months later. CCF caused by a PPTA trunk aneurysm is extremely rare. We speculate that the PPTA trunk aneurysm formed and then ruptured due to hemodynamic stress caused by hypoplasia of the basilar artery. PMID:21785245

  7. Uterine cavernous haemangioma in a post-menopausal woman: CT and MRI findings mimicking uterine myoma with degeneration

    OpenAIRE

    Lee, E J; Kim, S H; Kim, Y.H.(Center for Underground Physics, Institute for Basic Science (IBS), Daejon, 305-811, Korea)

    2011-01-01

    Cavernous haemangioma is a very rare vascular malformation of the uterus. We describe the CT and MRI findings of a cavernous haemangioma in an 81-year-old female with recurrent menorrhagia. CT showed a well-marginated mass with multifocal calcifications and extensive haemorrhage, as well as necrosis in the anterior wall of the uterus. MRI revealed heterogeneous low- to high-signal intensities of the mass on T1 and T2 weighted images as well as portions with poor enhancement of the mass on con...

  8. The first section of the CMS detector (centre of photo) arriving from the vertical shaft, viewed from the cavern floor.

    CERN Document Server

    Maximilien Brice

    2006-01-01

    In the early morning of 2 November, the first section of the CMS detector began its eagerly awaited descent into the underground cavern. You may imagine the CMS detector as a loaf of sliced bread, cut into 15 slices of different sizes. The two HF sections are the end pieces; the slices in between will be lowered sequentially according to their positions in the ‘loaf', starting from the HF+ section at the far end of the cavern, towards the access shaft at the opposite end.

  9. Treatment of a cavernous sinus dural arteriovenous fistula by deep orbital puncture of the superior ophthalmic vein

    International Nuclear Information System (INIS)

    In a patient with progressive ophthalmological problems, including uncontrolled intraocular pressure related to a cavernous sinus dural arteriovenous fistula, urgent intervention may be necessary to prevent permanent visual loss. We report a case in which inadequate transarterial embolisation and lack of access for transvenous catheterisation, including a direct approach through the superior ophthalmic vein, preceded percutaneous puncture of the superior ophthalmic vein deep within the orbit, permitting venous occlusion without complications. This case demonstrates that deep orbital puncture of the vein is feasible for occlusion of a cavernous sinus dural arteriovenous fistula. (orig.)

  10. Visits to the ATLAS cavern - A record of 20000 visitors in 2006!

    CERN Multimedia

    Alessandra Ciocio

    The year 2006 closed with the impressive record of just under 20000 visitors to the ATLAS cavern. These visitors come from all walks of life - people within ATLAS, groups from other CERN divisions, retired CERN staff, school groups both from the local area and from far away, companies looking for something different as a special outing, celebrities (Cirque du Soleil, Black Eyed Peas hip-hop group) passing through Geneva who had read Angels and Demons, a stream of VIP visitors and now, more and more, Press visitors. There have been public visits in the ATLAS cavern since the middle of 2003. At that time a lot of the visitors were guided by Bernard Lebegue and Francois Butin. The total number of visits in 2003 was 2220 people. Not bad for just two guides! Over the following three years demand for visits increased to such an extent that the ATLAS Visits Service was created and is now run very successfully under the supervision of Connie Potter in the ATLAS Secretariat in close collaboration with the ever-helpfu...

  11. Fístula carotídeo-cavernosa Carotid-cavernous fistula

    Directory of Open Access Journals (Sweden)

    Manuel Augusto Pereira Vilela

    2013-02-01

    Full Text Available Fístulas carotídeo-cavernosas são raras. São classificadas nos tipos direto e indireto. Fístulas diretas têm uma comunicação anormal entre a artéria carótida interna e o seio cavernoso. Nas formas indiretas a conexão se faz entre os ramos meningeos da carótida interna e/ou externa e o mesmo seio. O propósito deste artigo é o de atualizar os conceitos anatômicos, clínicos, diagnósticos e terapêuticos desta situação.Carotid cavernous fistulae are an uncommon disease. They are classified as direct or indirect. In direct fistulas there is an abnormal communication between the internal carotid artery and the cavernous sinus. Indirect forms have an abnormal bypass between the meningeal branches of the internal and/or external carotid arteries and the same sinus. The purpose of this article is to provide an overview of the anatomy of the envolved area and the clinical findings, diagnostic evaluation and treatment.

  12. TIPS Placement via Combined Transjugular and Transhepatic Approach for Cavernous Portal Vein Occlusion: Targeted Approach

    Directory of Open Access Journals (Sweden)

    Natanel Jourabchi

    2013-01-01

    Full Text Available Purpose. We report a novel technique which aided recanalization of an occluded portal vein for transjugular intrahepatic portosystemic shunt (TIPS creation in a patient with symptomatic portal vein thrombosis with cavernous transformation. Some have previously considered cavernous transformation a contraindication to TIPS. Case Presentation. 62-year-old man with chronic pancreatitis, portal vein thrombosis, portal hypertension and recurrent variceal bleeding presents with melena and hematemesis. The patient was severely anemic, hemodynamically unstable, and required emergent portal decompression. Attempts to recanalize the main portal vein using traditional transjugular access were unsuccessful. After percutaneous transhepatic right portal vein access and navigation of a wire through the occluded main portal vein, an angioplasty balloon was inflated at the desired site of shunt takeoff. The balloon was targeted and punctured from the transjugular approach, and a wire was passed into the portal system. TIPS placement then proceeded routinely. Conclusion. Although occlusion of the portal vein increases difficulty of performing TIPS, it should not be considered an absolute contraindication. We have described a method for recanalizing an occluded portal vein using a combined transhepatic and transjugular approach for TIPS. This approach may be useful to relieve portal hypertension in patients who fail endoscopic and/or surgical therapies.

  13. Apparent glacially induced structural controls on limestone conduit development in Ohio Caverns, United States

    Directory of Open Access Journals (Sweden)

    Adrienne M. Watts

    2016-01-01

    Full Text Available Rock discontinuities such as bedding planes and joints are important controls on the form that caves take. We examined structural controls on the development of Ohio Caverns. The cave formed in Devonian limestone underlying a small bedrock knob (Mt. Tabor within the Interior Lowland province, United States. The area has been overridden by continental glaciation multiple times. The bedrock is pervasively fractured, with many curved and wavy near-vertical fractures showing many different orientations. In the case of Ohio Caverns, it appears that the controlling fractures in map view may not be joints sensu stricto, but rather some combination of tensile and shear (mode-1 and mode-2 fractures, probably forming in the regime transition between tensile and shear fracturing. This is easy to envision in a situation with ice advancing over this topographic high, and would result in the curved fractures that are observed in many places in the cave. It can also explain the numerous fracture directions. However, not all fractures are conduit-significant. The cave initiated on or near a single bedding plane, and the cave passages exhibit strong keyhole or plus-sign cross sections. Passage and fracture orientations are inconsistent with regionally expected directions. It is likely that mechanical, hydraulic, and thermal stresses related to glaciation caused the fracturing in Mt. Tabor. The cave then developed on this template according to local hydrologic conditions. This presents a newly documented structural template sub-type for cave development.

  14. Surrounding rock mass stability monitoring of underground caverns in a geomechanical model test using FBG sensors

    Science.gov (United States)

    Li, Yong; Zhu, Weishen; Zheng, Wenhua; He, Jianping

    2009-07-01

    Fiber Bragg Gratings (FBG) sensor is widely accepted as a structural stability device for all kinds of geomaterials by either embedding into or bonding onto the structures. The physical model in geotechnical engineering, which can accurately simulate the construction processes and the effects on the stability of underground caverns on basis of satisfying the similarity principles, is an actual physical entity. Due to a large number of restrained factors, a series of experiments are difficult to be carried out, in particular for how to obtain physical parameters during the experiments. Using the geo-mechanical model test of underground caverns in Shuangjiangkou Hydropower Station as a research object, the FBG sensors were mainly focused on and adopted to figure out the problem how to achieve the small displacements in the large-scale model test. The final experimental results show that the FBG sensor has higher measuring accuracy than other conventional sensors like strain gages and mini-extensometers. The experimental results agree well with the numerical simulation results. In the process of building the model, it's successful to embed the FBG sensors in the physical model through making a reserved pore and adding some special glue. In conclusion, FBG sensors can effectively measure the small displacement of monitoring points in the whole process of the geomechanical model test. The experimental results reveal the deformation and failure characteristics of the surrounding rock mass and make some guidance for the in-situ engineering construction.

  15. Gamma knife radiosurgery for benign cavernous sinus tumors. Treatment concept and outcomes in 120 cases

    International Nuclear Information System (INIS)

    Availability of modern computer-aided robotized devices, such as the Automatic Positioning System (APSTM; Elekta Instruments AB, Stockholm, Sweden) and PerfexionTM (Elekta Instruments AB), allowed us to develop the original concept of robotic gamma knife microradiosurgery, which is based on the very precise irradiation of the lesion with regard to conformity and selectivity; intentional avoidance of the excessive irradiation of functionally-important anatomical structures, particularly cranial nerves, located both within and in the vicinity of the target; and delivery of sufficient irradiation energy to the tumor with the intention to attain lesion shrinkage, while keeping the marginal dose sufficiently low for prevention of possible complications. The results of such treatment strategy were evaluated retrospectively in 120 patients with benign cavernous sinus neoplasms (pituitary adenomas, meningiomas, schwannomas, and hemangiomas), who were followed up from 24 to 78 months (mean 47 months) after radiosurgery. Tumor growth control and shrinkage rates were 98% and 68%, respectively. More than 50% volume reduction was noted in 25% of lesions. The most prominent volumetric tumor response was observed in hemangiomas, followed by schwannomas, pituitary adenomas, and meningiomas. Treatment-related complications were marked in 7% of cases, and were mainly related to transient isolated cranial neuropathy appearing within several months after radiosurgery. Major morbidity was limited to one patient (0.8%). Application of microradiosurgical treatment principles provides effective and safe management of benign cavernous sinus tumors and is associated with high probability of lesion shrinkage and minimal risk of complications. (author)

  16. Transarterial Embolization of Traumatic Carotid-cavernous Fistulae by Gugliemi Detachable Coils: A Seven-year Experience

    OpenAIRE

    Luo, Chao-Bao; Mu-Huo Teng, Michael; Lin, Chung-Jung; Chang, Feng-Chi; Chang, Cheng-Yen

    2008-01-01

    We report our experience with transarterial embolization of traumatic carotid-cavernous fistulae (TCCFs) by using Gugliemi detachable coil (GDC). From 2000 to 2007 at our institution, 11 patients with 12 TCCFs underwent transarterial GDC embolization because of failure to occlude fistulae by detachable balloon with preservation of the parent artery.

  17. Vascular lesions of the lumbar epidural space: magnetic resonance imaging features of epidural cavernous hemangioma and epidural hematoma

    Directory of Open Access Journals (Sweden)

    Basile Júnior Roberto

    1999-01-01

    Full Text Available The authors report the magnetic resonance imaging diagnostic features in two cases with respectively lumbar epidural hematoma and cavernous hemangioma of the lumbar epidural space. Enhanced MRI T1-weighted scans show a hyperintense signal rim surrounding the vascular lesion. Non-enhanced T2-weighted scans showed hyperintense signal.

  18. Numerical study on criteria for design and operation of water curtain system in underground oil storage cavern using site descriptive fracture networks

    Science.gov (United States)

    Moon, Jiwon; Yeo, In Wook

    2013-04-01

    Underground unlined caverns have been constructed in fractured rocks to stockpile oil and petroleum products, where they are hydraulically contained by natural groundwater pressure. However, for the case that natural groundwater pressure is not maintained at the required level, water curtain boreholes, through which water is injected, are often constructed above the cavern as engineering barrier to secure water pressure enough to overwhelm the operational pressure of the cavern. For secure containment of oil and petroleum products inside the cavern, it is essential to keep water pressure around the cavern higher than operational pressure of the cavern using either natural groundwater pressure or engineering barrier. In the Republic of Korea, a number of underground stockpile bases are being operated by Korea National Oil Corporation (KNOC) and private companies, most of which have water curtain system. The criterion that KNOC adopts for water curtain system design and operation such as the vertical distance from the cavern and operational injection rate is based on the Åberg hypothesis that the vertical hydraulic gradient should be larger than one. The criterion has been used for maintaining oil storage cavern without its thorough review. In this study, systematic numerical works have been done for reviewing the Åberg criterion. As groundwater predominantly takes places through fractures in underground caverns, discrete fracture modeling approach is essential for this study. Fracture data, obtained from boreholes drilled at the stage of site investigation at the Yeosu stockpile base in Korea, were statistically analyzed in terms of orientation and intensity, which were used to generate the site descriptive three dimensional fracture networks. Then, groundwater flow modeling has been carried out for the fracture networks. Constant head boundaries were applied along the circumference of the cavern and water curtain boreholes. Main flow channel and hydraulic

  19. Stability and support issues in the construction of large span caverns for physics

    Energy Technology Data Exchange (ETDEWEB)

    Laughton, C.; /Fermilab

    2008-05-01

    New physics experiments, proposed to study neutrinos and protons, call for the use of large underground particle detectors. In the United States, such detectors would be housed in the US Deep Underground Science and Engineering Laboratory (DUSEL), sited within the footprint of the defunct Homestake Mine, South Dakota. Although the experimental proposals differ in detail, all rely heavily upon the ability of the mined and reinforced rock mass to serve as a stable host for the detector facilities. Experimental proposals, based on the use of Water Cherenkov detector technology, specify rock caverns with excavated volumes in excess of half a million cubic meters, spans of at least 50 m, sited at depths of approximately one to 1.5 kilometers. Although perhaps sited at shallower depth, proposals based on the use of Liquid Argon (LAr) detector technology are no less challenging. LAr proposals not only call for the excavation of large span caverns, but have an additional need for the safe management of large quantities (kilo-tonnes) of cryogenic liquid, including critical provisions for the fail-safe egress of underground personnel and the reliable exhaust of Argon gas in the event of a catastrophic release. These multi-year, high value physics experiments will provide the key experimental data needed to support the research of a new generation of physicists as they probe the behavior of basic particles and the fundamental laws of nature. The rock engineer must deliver caverns that will reliably meet operational requirements and remain stable for periods conservatively estimated to be in excess of twenty years. This paper provides an overview of the DUSEL site conditions and discusses key end-user requirements and design criteria likely to dominate in determining the viability of experimental options. The paper stresses the paramount importance of collecting adequate site-specific data to inform early siting, dimensioning and layout decisions. Given the large-scale of the

  20. A locus for cerebral cavernous malformations maps to chromosome 7q in two families

    Energy Technology Data Exchange (ETDEWEB)

    Marchuk, D.A.; Gallione, C.J. [Duke Univ. Medical Center, Durham, NC (United States); Morrison, L.A.; Davis, L.E.; Clericuzio, C.L. [Univ. of New Mexico School of Medicine, Albuquerque, NM (United States)] [and others

    1995-07-20

    Cavernous malformations (angiomas) affecting the central nervous system and retina can be inherited in autosomal dominant pattern (OMIM 116860). These vascular lesions may remain clinically silent or lead to a number of neurological symptoms including seizure, intracranial hemorrhage, focal neurological deficit, and migraine. We have mapped a gene for this disorder in two families, one of Italian-American origin and one of Mexican-American origin, to markers on proximal 7q, with a combined maximum lod score of 3.92 ({theta} of zero) with marker D7S479. Haplotype analysis of these families places the locus between markers D7S502 proximally and D7S515 distally, an interval of approximately 41 cM. The location distinguishes this disorder from an autosomal dominant vascular malformation syndrome where lesions are primarily cutaneous and that maps to 9p21. 16 refs., 3 figs., 1 tab.

  1. CNS cavernous haemangioma: “popcorn” in the brain and spinal cord

    International Nuclear Information System (INIS)

    Cavernous haemangiomas (CH) are relatively uncommon non-shunting vascular malformations of the central nervous system and can present with seizures or with neurological deficits due to haemorrhage. Radiologists can often suggest the diagnosis of CH based on characteristic magnetic resonance imaging (MRI) features, thus avoiding further invasive procedures such as digital subtraction angiography or surgical biopsy. Although typical MRI appearance combined with the presence of multiple focal low signal lesions on T2*-weighted images or the presence of one or more developmental venous anomaly within the brain can improve the diagnostic confidence, serial imaging studies are often required if a solitary CH presents at a time when the imaging appearances had not yet matured to the typical “popcorn” appearance.

  2. [A Case Report of Stereotactic Craniotomy for the Cerebral Cavernous Angioma].

    Science.gov (United States)

    Ota, Yuichiro; Araki, Osamu; Oki, Shuichi; Inagawa, Tetsuji; Emoto, Katsuya; Shibukawa, Masaaki; Yamasaki, Hiroyuki; Kano, Yukari; Tani, Itaru

    2016-02-01

    A 59-year-old woman presented with right sensory loss and right hemiparesis. In February 2013, she was admitted to Araki Neurosurgical Hospital. A magnetic resonance imaging was performed that revealed a left temporal lobe hemorrhage. The image also showed a chronic stereotype hematoma. After 14 days of hospitalization, she underwent a stereotactic craniotomy. Subsequently, by postoperative pathological evaluation, the hematoma was diagnosed as a cavernous angioma. She had no postoperative complications. She was provided rehabilitation support and was discharged 28 days after the admission following which she rejoined work. A stereotactic craniotomy device is very useful in surgeries involving deep lesions. We present a case of stereotactic craniotomy and a few investigation reports. PMID:26856269

  3. CNS cavernous haemangioma: 'popcorn' in the brain and spinal cord

    Energy Technology Data Exchange (ETDEWEB)

    Hegde, A.N. [Department of Neuroradiology, National Neuroscience Institute (Singapore); Department of Diagnostic Imaging, National University Hospital (Singapore); Mohan, S. [Department of Neuroradiology, National Neuroscience Institute (Singapore); Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia (United States); Lim, C.C.T., E-mail: Tchoyoson_lim@nni.com.sg [Department of Neuroradiology, National Neuroscience Institute (Singapore); Department of Neurology, Duke NUS Graduate Medical School (Singapore)

    2012-04-15

    Cavernous haemangiomas (CH) are relatively uncommon non-shunting vascular malformations of the central nervous system and can present with seizures or with neurological deficits due to haemorrhage. Radiologists can often suggest the diagnosis of CH based on characteristic magnetic resonance imaging (MRI) features, thus avoiding further invasive procedures such as digital subtraction angiography or surgical biopsy. Although typical MRI appearance combined with the presence of multiple focal low signal lesions on T2*-weighted images or the presence of one or more developmental venous anomaly within the brain can improve the diagnostic confidence, serial imaging studies are often required if a solitary CH presents at a time when the imaging appearances had not yet matured to the typical 'popcorn' appearance.

  4. Characterization of bedded salt for storage caverns -- A case study from the Midland Basin, Texas

    Energy Technology Data Exchange (ETDEWEB)

    Hovorka, Susan D.; Nava, Robin

    2000-06-13

    The geometry of Permian bedding salt in the Midland Basin is a product of interaction between depositional facies and postdepositional modification by salt dissolution. Mapping high-frequency cycle patterns in cross section and map view using wireline logs documents the salt geometry. Geologically based interpretation of depositional and dissolution processes provides a powerful tool for mapping and geometry of salt to assess the suitability of sites for development of solution-mined storage caverns. In addition, this process-based description of salt geometry complements existing data about the evolution of one of the best-known sedimentary basins in the world, and can serve as a genetic model to assist in interpreting other salts.

  5. Zenithal ceiling tubes, a peculiar karst corrosion form in Carlsbad Caverns (New Mexico, USA)

    Science.gov (United States)

    Calaforra, José Maria; de Waele, Jo

    2010-05-01

    Carlsbad Caverns is a world renown show cave located in the Guadalupe Mountains (Chihuahuan desert, New Mexico) and managed by the United States National Park Service. The cave is hosted in the Permian Capitan Reef limestones that border the Delaware basin. It consists of elongated passages connecting wide rooms that extend to a depth of almost 300 m beneath the natural cave entrance, almost 200 m below the floor of nearby Walnut Canyon. As most caves of the Guadalupe mountains it has formed by rising hydrogen sulphide deriving from underlying oil and gas deposits, producing sulphuric acid by mixing with fresh water which corroded the limestone into unusually large chambers. This H2SO4 speleogenesis has produced gypsum that is present under various forms. Carlsbad Caverns has been widely studied by generations of cave scientists, and research has especially focalised on speleothems, mineralogy, speleogenesis, cave fauna and, mostly in the last decennia, microbiology. This has resulted in a large number of publications in many scientific journals, making Carlsbad Caverns one of the best studied caves of the world. During a trip to the Hall of the White Giant, in the squeezing crawlways that connect the main Corridor to the Sand Passage, several cylindrical vertical upward developing holes were observed on the ceiling at several heights. They have a circular cross-section with diameters of 1 to some centimetres and taper out towards their upper end. Their walls are smooth and their edges sharp. Their length can reach several decimetres. Sometimes gypsum can be found inside. They often occur randomly distributed in groups and their development is not necessarily controlled by fractures or other bedrock structures. These holes are similar in shape to the bellholes described from many tropical caves, but are much smaller. They also look like the holes described by Stanton (1986) from caves in the Mendip Hills. This author believed they formed by activity of snails (they

  6. Unilateral facial palsy in an infant: an unusual presentation of familial multiple cerebral cavernous malformation.

    LENUS (Irish Health Repository)

    Zakaria, Zaitun

    2012-01-01

    Cerebral cavernous malformation (CCM) in infants tends to have genetic predisposition. These cavernomas have a progressive course of events and associated neurological symptoms with increase in age. They most commonly present with seizure and syndrome of increased intracranial pressure comprising of headache, vomiting and focal neurological signs. We describe a case of a 7-month-old infant who presented with an acute onset of right facial paralysis with a background of familial CCM. The CT and MRI scan revealed fresh haemorrhage in the right cerebellar and pontine cavernomas with surrounding oedema and no evidence of obstructive hydrocephalus. These two cavernomas re-bled in a week duration causing episodes of incessant crying and irritability. After discussing the pros and cons of treatment, owing to stable clinical status, the patient is currently been managed conservatively.

  7. Indirect cavernous carotid fistula in a 12-year-old girl

    Science.gov (United States)

    Livi, Francesca; Ndoro, Samuel; Caird, John; Crimmins, Darach

    2016-01-01

    We present a very rare case of indirect cavernous carotid fistula (CCF) in a 12-year-old girl. Indirect CCF is extremely rare in the paediatric population. A 12-year-old girl presented with a 7-month history of frontal headaches and intermittent left-sided proptosis. On examination, she had dilated and engorged scleral veins on the left eye, mild dysdiadochokinesia and past pointing on the left side. A brain computer tomography with contrast, brain magnetic resonance imaging (MRI) and interventional radiography (IR) cerebral angiogram confirmed the diagnosis of CCF. The CCF was embolized and a follow-up brain MRI and an IR cerebral angiogram were conducted over the course of 8 months that revealed no evidence of residual CCF. CCF, though rare in the paediatric population, should be highly considered in the differential diagnosis when dilated scleral veins, proptosis and dysdiadokinesis are present in the clinical setting. Prompt treatment has good prognostic results. PMID:27273682

  8. High voltage irradiation of a cavernous giant haemangioma? An impressive case example

    International Nuclear Information System (INIS)

    Because of multifonus of therapeutic possibilities in treating cavernous haemangioma, we mostly, but primarily due to frequent spontaneous regression tendency, we exercise restraint. However, if irradiation is taken into consideration, it is mainly with 'soft' X-rays (100 kV). The application of high voltage X-rays (1 MeV) by means of linear accelerator is seldom and rarely found in literature. That this method can be effective and indication for this is absolutely in order and life-saving, is described in an impressive case example of a congenital giant haemangioma on the right facial half of an infant, where all other previous forms of therapeutical procedures had failed. (orig.)

  9. Improved Vision from Severe Compressive Optic Neuropathy by Apical Cavernous Hemangioma.

    Science.gov (United States)

    Kang, Hyera; Takahashi, Yasuhiro; Nishimura, Kunihiro; Yasuda, Muneyoshi; Akutsu, Hiroyoshi; Kakizaki, Hirohiko

    2016-01-01

    A 59-year-old woman had a 1-year history of right vision loss. Her visual acuity was then 0.01 OD, and the critical flicker frequency (CFF) was 8 Hz OD. Goldmann perimetry examination showed inferior suppression of the right visual field center. Funduscopic examination revealed normal coloring of the right optic disc. Imaging studies showed an apical oval tumor. The optic nerve was compressed by both the tumor and the superior rectus muscle/levator palpebrae superioris complex. The tumor was dissected from the surrounding tissues and completely extracted. Histopathologic examination confirmed a cavernous hemangioma. The patient underwent three cycles of postoperative steroid pulse therapy. One year after the surgery, her visual acuity and CFF improved to 1.0 and 32 Hz OD, respectively. Her right visual field was within the normal range. PMID:27099610

  10. Cavernous sinus thrombosis syndrome and brainstem involvement in patient with leptospirosis: Two rare complications of leptospirosis

    Science.gov (United States)

    Alian, Shahriyar; Taghipour, Mehrdad; Sharifian, Rayka; Fereydouni, Mohammad Amin

    2014-01-01

    Leptospirosis is a bacterial disease that is caused by pathogenic spirochetes of the genus Leptospira. It can affect humans and animals. In humans, it can lead to a wide spectrum of symptoms. It is known as the most common zoonosis in the world. The typical presentation of the disease is an acute biphasic febrile illness with or without jaundice. Less common clinical manifestations may result from involvement of different human body systems. In many places, this disease may be under-diagnosed, especially when associated with neurological complications. Moreover, without treatment, leptospirosis can lead to organ damages, and even death. Neurological complications are uncommon and are reported in a few cases. Cavernous sinus thrombosis syndrome and brainstem involvement are rare complications of leptospirosis and are associated with a high mortality risk. To our knowledge, no such cases have been reported in the literature. PMID:25535508

  11. Cranial nerve assessment in cavernous sinus tumors with contrast-enhanced 3D fast-imaging employing steady-state acquisition MR imaging

    International Nuclear Information System (INIS)

    The purpose of this study is to apply contrast-enhanced 3D fast-imaging employing steady-state acquisition (3D-FIESTA) imaging to the evaluation of cranial nerves (CN) in patients with cavernous sinus tumors. Contrast-enhanced 3D-FIESTA images were acquired from ten patients with cavernous sinus tumors with a 3-T unit. In all cases, the trigeminal nerve with tumor involvement was easily identified in the cavernous portions. Although oculomotor and abducens nerves were clearly visualized against the tumor area with intense contrast enhancement, they were hardly identifiable within the area lacking contrast enhancement. The trochlear nerve was visualized in part, but not delineated as a linear structure outside of the lesion. Contrast-enhanced 3D-FIESTA can be useful in the assessment of cranial nerves in and around the cavernous sinus with tumor involvement. (orig.)

  12. Cranial nerve assessment in cavernous sinus tumors with contrast-enhanced 3D fast-imaging employing steady-state acquisition MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Amemiya, Shiori; Aoki, Shigeki; Ohtomo, Kuni [University of Tokyo, Department of Radiology, Graduate School of Medicine, Bunkyo-ku, Tokyo (Japan)

    2009-07-15

    The purpose of this study is to apply contrast-enhanced 3D fast-imaging employing steady-state acquisition (3D-FIESTA) imaging to the evaluation of cranial nerves (CN) in patients with cavernous sinus tumors. Contrast-enhanced 3D-FIESTA images were acquired from ten patients with cavernous sinus tumors with a 3-T unit. In all cases, the trigeminal nerve with tumor involvement was easily identified in the cavernous portions. Although oculomotor and abducens nerves were clearly visualized against the tumor area with intense contrast enhancement, they were hardly identifiable within the area lacking contrast enhancement. The trochlear nerve was visualized in part, but not delineated as a linear structure outside of the lesion. Contrast-enhanced 3D-FIESTA can be useful in the assessment of cranial nerves in and around the cavernous sinus with tumor involvement. (orig.)

  13. A servo controlled gradient loading triaxial model test system for deep-buried cavern

    International Nuclear Information System (INIS)

    A servo controlled gradient loading model test system is developed to simulate the gradient geostress in deep-buried cavern. This system consists of the gradient loading apparatus, the digital servo control device, and the measurement system. Among them, the gradient loading apparatus is the main component which is used for exerting load onto the model. This loading apparatus is placed inside the counterforce wall/beam and is divided to several different loading zones, with each loading zone independently controlled. This design enables the gradient loading. Hence, the “real” geostress field surrounding the deep-buried cavern can be simulated. The loading or unloading process can be controlled by the human-computer interaction machines, i.e., the digital servo control system. It realizes the automation and visualization of model loading/unloading. In addition, this digital servo could control and regulate hydraulic loading instantaneously, which stabilizes the geostress onto the model over a long term. During the loading procedure, the collision between two adjacent loading platens is also eliminated by developing a guide frame. This collision phenomenon is induced by the volume shrinkage of the model when compressed in true 3D state. In addition, several accurate measurements, including the optical and grating-based method, are adopted to monitor the small deformation of the model. Hence, the distortion of the model could be accurately measured. In order to validate the performance of this innovative model test system, a 3D geomechanical test was conducted on a simulated deep-buried underground reservoir. The result shows that the radial convergence increases rapidly with the release of the stress in the reservoir. Moreover, the deformation increases with the increase of the gas production rate. This observation is consistence with field observation in petroleum engineering. The system is therefore capable of testing deep-buried engineering structures

  14. Lacrimal Sac Mucoepidermoid Carcinoma with Metastases to the Cavernous Sinus Following Dacryocystorhinostomy Treated with Stereotactic Radiotherapy

    Directory of Open Access Journals (Sweden)

    Jonathan C.P. Roos

    2016-05-01

    Full Text Available Purpose: We report a very good outcome in a 44-year-old woman in whom cancer was missed as the cause of nasolacrimal duct obstruction and dacryocystitis and which was deemed inoperable after spreading to the cavernous sinus. Case Report: The patient was referred to our unit 12 months following uneventful right dacryocystorhinostomy for nasolacrimal duct obstruction. This had been complicated by the formation of a significant canthal swelling 6 months later, which had been excised at that time. The symptom of nasolacrimal duct obstruction and scar recurrence prompted the referral to our unit. Examination and biopsy confirmed a malignancy. Despite extensive surgery, including concurrent radical neck dissection and parotidectomy, within 6 months, her mucoepidermoid carcinoma was found to have spread to the cavernous sinus, restricting blood flow from the carotid and causing an abducens nerve palsy. Though deemed inoperable at first, Gamma Knife stereotactic radiosurgery was sought as treatment for her disease, resulting in a good outcome 4 years after surgery. Conclusion: Experience from this case suggests the importance of considering malignancy as a cause in young patients when presenting with nasolacrimal duct obstruction. In such cases, and perhaps for all patients, biopsy specimens should be submitted as many tumours are found incidentally at the time of dacryocystorhinostomy. Whilst the external approach to dacryocystorhinostomy may identify abnormal anatomy intraoperatively, prompting biopsy, this is less likely with an endonasal approach where osteotomy precedes sac visualisation. The endonasal approach may therefore be less appropriate in such cases where malignancy is suspected as osteotomy may aid in the spread.

  15. A servo controlled gradient loading triaxial model test system for deep-buried cavern

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Xu-guang [College of Engineering, Ocean University of China, Qingdao 266100 (China); Shandong Provincial Key Laboratory of Ocean Engineering, Qingdao 266100 (China); Research Center of Geotechnical and Structural Engineering, Shandong University, Jinan 250061 (China); Zhang, Qiang-yong; Li, Shu-cai [Research Center of Geotechnical and Structural Engineering, Shandong University, Jinan 250061 (China)

    2015-10-15

    A servo controlled gradient loading model test system is developed to simulate the gradient geostress in deep-buried cavern. This system consists of the gradient loading apparatus, the digital servo control device, and the measurement system. Among them, the gradient loading apparatus is the main component which is used for exerting load onto the model. This loading apparatus is placed inside the counterforce wall/beam and is divided to several different loading zones, with each loading zone independently controlled. This design enables the gradient loading. Hence, the “real” geostress field surrounding the deep-buried cavern can be simulated. The loading or unloading process can be controlled by the human-computer interaction machines, i.e., the digital servo control system. It realizes the automation and visualization of model loading/unloading. In addition, this digital servo could control and regulate hydraulic loading instantaneously, which stabilizes the geostress onto the model over a long term. During the loading procedure, the collision between two adjacent loading platens is also eliminated by developing a guide frame. This collision phenomenon is induced by the volume shrinkage of the model when compressed in true 3D state. In addition, several accurate measurements, including the optical and grating-based method, are adopted to monitor the small deformation of the model. Hence, the distortion of the model could be accurately measured. In order to validate the performance of this innovative model test system, a 3D geomechanical test was conducted on a simulated deep-buried underground reservoir. The result shows that the radial convergence increases rapidly with the release of the stress in the reservoir. Moreover, the deformation increases with the increase of the gas production rate. This observation is consistence with field observation in petroleum engineering. The system is therefore capable of testing deep-buried engineering structures.

  16. A servo controlled gradient loading triaxial model test system for deep-buried cavern.

    Science.gov (United States)

    Chen, Xu-guang; Zhang, Qiang-yong; Li, Shu-cai

    2015-10-01

    A servo controlled gradient loading model test system is developed to simulate the gradient geostress in deep-buried cavern. This system consists of the gradient loading apparatus, the digital servo control device, and the measurement system. Among them, the gradient loading apparatus is the main component which is used for exerting load onto the model. This loading apparatus is placed inside the counterforce wall/beam and is divided to several different loading zones, with each loading zone independently controlled. This design enables the gradient loading. Hence, the "real" geostress field surrounding the deep-buried cavern can be simulated. The loading or unloading process can be controlled by the human-computer interaction machines, i.e., the digital servo control system. It realizes the automation and visualization of model loading/unloading. In addition, this digital servo could control and regulate hydraulic loading instantaneously, which stabilizes the geostress onto the model over a long term. During the loading procedure, the collision between two adjacent loading platens is also eliminated by developing a guide frame. This collision phenomenon is induced by the volume shrinkage of the model when compressed in true 3D state. In addition, several accurate measurements, including the optical and grating-based method, are adopted to monitor the small deformation of the model. Hence, the distortion of the model could be accurately measured. In order to validate the performance of this innovative model test system, a 3D geomechanical test was conducted on a simulated deep-buried underground reservoir. The result shows that the radial convergence increases rapidly with the release of the stress in the reservoir. Moreover, the deformation increases with the increase of the gas production rate. This observation is consistence with field observation in petroleum engineering. The system is therefore capable of testing deep-buried engineering structures. PMID

  17. Decompressed zones surrounding tunnels and caverns in the Valanginien marl of the Oberbauenstock

    International Nuclear Information System (INIS)

    At the Oberbauenstock Type B repository model site for low and intermediate level radwaste, tunnels and caverns will be surrounded by decompressed zones which are induced through the stress redistributions caused by the tunnelling action. The following report treats the formation, the extent and the inherent properties of the decompressed - or loosened -zone. The loosening may be accompanied by an increase of the hydraulic permeability (k-value). For the Valanginien marl (host rock), the k-value is considered to change from 10-10 m/s to approx. 10-7 m/s. The swelling potential of the marl induces the so-called joint swelling in the plastified rock zones; this can reduce the final k-value to 10-8 -10-9 m/s. Over long periods of time, creep of the marl under the given overburden stress might, following backfilling of the tunnels and caverns, additionally reduce the permeability. However, present indications are that the viscosity of the Valanginien marl is too high to allow a significant recompression of the decompressed zones. The permeability, however, may possibly be reduced by grouting techniques. It is proposed to study the mechanisms of rock loosening, joint swelling and creeping in more detail by means of in situ and laboratory investigations. The report includes the large-scale determination of the permeability of naturally jointed rock, making use of seepage measurements on power tunnels in the Swiss Alps. Comparisons may then be carried out between the naturally jointed rock and the 'artificially' jointed decompressed rock zone with regard to their permeability. (author)

  18. A servo controlled gradient loading triaxial model test system for deep-buried cavern

    Science.gov (United States)

    Chen, Xu-guang; Zhang, Qiang-yong; Li, Shu-cai

    2015-10-01

    A servo controlled gradient loading model test system is developed to simulate the gradient geostress in deep-buried cavern. This system consists of the gradient loading apparatus, the digital servo control device, and the measurement system. Among them, the gradient loading apparatus is the main component which is used for exerting load onto the model. This loading apparatus is placed inside the counterforce wall/beam and is divided to several different loading zones, with each loading zone independently controlled. This design enables the gradient loading. Hence, the "real" geostress field surrounding the deep-buried cavern can be simulated. The loading or unloading process can be controlled by the human-computer interaction machines, i.e., the digital servo control system. It realizes the automation and visualization of model loading/unloading. In addition, this digital servo could control and regulate hydraulic loading instantaneously, which stabilizes the geostress onto the model over a long term. During the loading procedure, the collision between two adjacent loading platens is also eliminated by developing a guide frame. This collision phenomenon is induced by the volume shrinkage of the model when compressed in true 3D state. In addition, several accurate measurements, including the optical and grating-based method, are adopted to monitor the small deformation of the model. Hence, the distortion of the model could be accurately measured. In order to validate the performance of this innovative model test system, a 3D geomechanical test was conducted on a simulated deep-buried underground reservoir. The result shows that the radial convergence increases rapidly with the release of the stress in the reservoir. Moreover, the deformation increases with the increase of the gas production rate. This observation is consistence with field observation in petroleum engineering. The system is therefore capable of testing deep-buried engineering structures.

  19. Intracerebral cavernous hemangioma after cranial irradiation in childhood. Incidence and risk factors

    Energy Technology Data Exchange (ETDEWEB)

    Strenger, V.; Sovinz, P.; Lackner, H.; Dornbusch, H.J.; Moser, A.; Urban, C. [Graz Medical Univ. (Austria). Div. of Pediatric Hematology and Oncology; Lingitz, H. [Graz Medical Univ. (Austria). Dept. of Therapeutic Radiology and Oncology; Eder, H.G. [Graz Medical Univ. (Austria). Dept. of Neurosurgery

    2008-05-15

    Background and Purpose: Radiotherapy is an integral part of various therapeutic regimens in pediatric and adult oncology. Endocrine dysfunction, neurologic and psychiatric deficits, secondary malignancies and radiation-induced necrosis are well-known possible late effects of cranial irradiation. However, only sporadic cases of radiation-induced cavernous hemangiomas (RICH) have been reported so far. Patients and Methods: Pediatric patients who underwent cranial radiation therapy for malignant diseases between January 1980 and December 2003 were retrospectively analyzed. After the end of therapy they entered a detailed follow-up program. Results: Of 171 patients, eight (three patients with medulloblastoma, three patients with acute lymphoblastic leukemia, and one patient each with ependymoma and craniopharyngioma) developed intracerebral cavernoma 2.9-18.4 years after irradiation representing a cumulative incidence (according to the Kaplan-Meier method) of 2.24%, 3.86%, 4.95%, and 6.74% within 5, 10, 15, and 20 years following radiation therapy, respectively. In patients treated in the first 10 years of life, RICH occurred with shorter latency and significantly more often (p = 0.044) resulting in an even higher cumulative incidence. Conclusion: These findings and previously published cases show that cavernous hemangiomas may occur after irradiation of the brain several years after the end of therapy irrespective of the radiation dose and type of malignancy. Particularly children < 10 years of age at the time of irradiation are at higher risk. Since patients with RICH frequently do not show symptoms but hemorrhage is a possible severe complication, imaging of the central nervous system should be performed routinely for longer follow- ups, particularly in patients who were treated as young children. (orig.)

  20. Case Report: Carotid–cavernous fistula due to aneurysmal rupture in a case of aortoaortitis with bilateral giant internal carotid artery aneurysms

    International Nuclear Information System (INIS)

    Takayasu aortoarteritis (TA) rarely affects the nervous system, but when it does, it usually manifests as cerebral ischemia or stroke. These strokes have mainly been attributed to stenotic extracranial vessels. Stenoses of intracranial vessels, although rare in TA, can occur due to either embolization into the vessel or because of the vasculitic process itself. Intracranial aneurysms are very rare in patients with TA. Bilateral cavernous internal carotid artery (ICA) aneurysms are rarer. They have been reported following radiation therapy and in association with fibromuscular dysplasia and juvenile Paget disease. Bilateral mycotic intracavernous aneurysms also occur. Bilateral giant cavernous ICA aneurysms with carotid-cavernous fistula (CCF) consequent to rupture into the cavernous sinus in a case of TA are extremely unusual. We report a case that fulfilled both American College of Rheumatology and European League against Rheumatology criteria for TA. The patient had bilateral cavernous sinus giant aneurysms and CCF because the right-sided aneurysm had ruptured and was leaking into the cavernous sinus

  1. Effects of anesthesia with isoflurane on plasma concentrations of adrenocorticotropic hormone in samples obtained from the cavernous sinus and jugular vein of horses.

    Science.gov (United States)

    Carmalt, James L; Duke-Novakovski, Tanya; Schott, Harold C; van der Kolk, Johannes H

    2016-07-01

    OBJECTIVE To determine effects of anesthesia on plasma concentrations and pulsatility of ACTH in samples obtained from the cavernous sinus and jugular vein of horses. ANIMALS 6 clinically normal adult horses. PROCEDURES Catheters were placed in a jugular vein and into the cavernous sinus via a superficial facial vein. The following morning (day 1), cavernous sinus blood samples were collected every 5 minutes for 1 hour (collection of first sample = time 0) and jugular venous blood samples were collected at 0, 30, and 60 minutes. On day 2, horses were sedated with xylazine hydrochloride and anesthesia was induced with propofol mixed with ketamine hydrochloride. Horses were positioned in dorsal recumbency. Anesthesia was maintained with isoflurane in oxygen and a continuous rate infusion of butorphanol tartrate. One hour after anesthesia was induced, the blood sample protocol was repeated. Plasma ACTH concentrations were quantified by use of a commercially available sandwich assay. Generalized estimating equations that controlled for horse and an expressly automated deconvolution algorithm were used to determine effects of anesthesia on plasma ACTH concentrations and pulsatility, respectively. RESULTS Anesthesia significantly reduced the plasma ACTH concentration in blood samples collected from the cavernous sinus. CONCLUSIONS AND CLINICAL RELEVANCE Mean plasma ACTH concentrations in samples collected from the cavernous sinus of anesthetized horses were reduced. Determining the success of partial ablation of the pituitary gland in situ for treatment of pituitary pars intermedia dysfunction may require that effects of anesthesia be included in interpretation of plasma ACTH concentrations in cavernous sinus blood. PMID:27347826

  2. Prediction versus actual response of rocks in an excavation of underground cavern at the Lam Ta Khong pumped storage project

    Energy Technology Data Exchange (ETDEWEB)

    Lertsgoon, P.N. [Electricity Generating Authority of Thailand, Bangkruai Nonthaburi (Thailand)

    2003-07-01

    The Lam Ta Khong Pumped Storage Project represents the first underground power plant in Thailand, and involves the excavation of a large underground cavern. Its dimensions are a 25 span, 175 metres long and 49 metres high. It is excavated in sandstone and siltstone and houses 4 power generator units capable of producing a maximum of 1000 mega watts (MW). The work was completed in 2000. The feasibility study revealed questionable properties of the siltstone which governs the ceiling of the cavern, due to a slacking phenomenon. A comparison between prediction and actual ground responses during excavation was performed for construction safety. PHASES and PHASE2 software were used for the prediction, while the actual rock response was obtained using a monitoring system. The parameters on rock properties from back calculation used in the design were made obvious by the correspondence between the prediction and the actual responses. 2 refs., 1 tab., 5 figs.

  3. Process for the manufacture of a dense cover of liquids and solids in underground stores, particularly in sumps of caverns

    Energy Technology Data Exchange (ETDEWEB)

    Kleinitz, W.

    1978-08-10

    In order to use salt caverns as stores, a coating material is used, which is applied as a solution or in the dispersion condition. The coating material consists of polyisobutyls with additives of polyisoprene and/or polybutadene. Its characteristics include good adhesion to rock salt, the formation of even films, good flow and therefore a self-healing surface. The substances used have negligible porosity for polar steam, due to their non-polarity.

  4. Process for the manufacture of a dense cover of liquids and solids in underground stores, particularly in sumps of caverns

    International Nuclear Information System (INIS)

    In order to use salt caverns as stores, a coating material is used, which is applied as a solution or in the dispersion condition. The coating material consists of polyisobutyls with additives of polyisoprene and/or polybutadene. Its characteristics include good adhesion to rock salt, the formation of even films, good flow and therefore a self-healing surface. The substances used have negligible porosity for polar steam, due to their non-polarity. (HGOE)

  5. Traumatic carotid-cavernous fistula associated with persistent primitive trigeminal artery treated by transarterial coil embolization--case report.

    Science.gov (United States)

    Kobayashi, Nozomu; Miyachi, Shigeru; Oi, Sachie; Yamamoto, Naohito

    2011-01-01

    A 30-year-old woman presented with traumatic carotid-cavernous fistula associated with persistent primitive trigeminal artery (PPTA) manifesting as right conjunctival chemosis, exophthalmos, and diplopia. The lesion was treated successfully by trans-arterial coil embolization using the double catheter method with balloon assist. Injury to the PPTA is relatively rare and the PPTA should be sacrificed together with the fistula during the repair. PMID:21273742

  6. Determination of hydraulic conductivity of fractured rock masses: A case study for a rock cavern project in Singapore

    OpenAIRE

    Zhipeng Xu; Zhiye Zhao; Jianping Sun; Ming Lu

    2015-01-01

    In order to reduce the risk associated with water seepage in an underground rock cavern project in Singapore, a reliable hydro-geological model should be established based on the in situ investigation data. The key challenging issue in the hydro-geological model building is how to integrate limited geological and hydro-geological data to determine the hydraulic conductivity of the fractured rock masses. Based on the data obtained from different stages (feasibility investigation stage, constru...

  7. Dural Venous System in the Cavernous Sinus: A Literature Review and Embryological, Functional, and Endovascular Clinical Considerations

    OpenAIRE

    Mitsuhashi, Yutaka; HAYASAKI, Koji; Kawakami, Taichiro; Nagata, Takashi; KANESHIRO, Yuta; UMABA, Ryoko; Ohata, Kenji

    2016-01-01

    The cavernous sinus (CS) is one of the cranial dural venous sinuses. It differs from other dural sinuses due to its many afferent and efferent venous connections with adjacent structures. It is important to know well about its complex venous anatomy to conduct safe and effective endovascular interventions for the CS. Thus, we reviewed previous literatures concerning the morphological and functional venous anatomy and the embryology of the CS. The CS is a complex of venous channels from embryo...

  8. Transarterial detachable coil embolization combined with ipsilateral intermittent carotid oppression for traumatic carotid-cavernous fistula with small fistula

    Institute of Scientific and Technical Information of China (English)

    Qing Huang; Hongbing Zhang; Gang Wang; Jun Yang; Yanlong Hu; Jianxin Liu

    2015-01-01

    One case of traumatic carotid-cavernous fistula (TCCF) with small fistula treated by transarterial detachable coil embolization was reported.The intermittent ipsilateral carotid compression was used to identify the final blocking of the residual fistula.The follow-up digital subtraction angiography showed that the TCCF was cured finally, From this case, we conclude that this method may be an effective way to treat TCCF with small fistula.

  9. Gene expression profile comparison in the penile tissue of diabetes and cavernous nerve injury-induced erectile dysfunction rat model

    Science.gov (United States)

    Kam, Sung Chul; Lee, Sang Hoon; Jeon, Ju Hong; So, Insuk; Chae, Mee Ree; Park, Jong Kwan

    2016-01-01

    Purpose To investigate the effects of cavernous nerve injury (CNI) on gene expression profiles in the cavernosal tissue of a CNI-induced erectile dysfunction (ED) model and to provide a basis for future investigations to discover potential target genes for ED treatment. Materials and Methods Young adult rats were divided randomly into 2 groups: sham operation and bilateral CN resection. At 12 weeks after CNI we measured erectile responses and performed microarray experiments and gene set enrichment analysis to reveal gene signatures that were enriched in the CNI-induced ED model. Alterations in gene signatures were compared with those in the diabetes-induced ED model. The diabetic-induced ED data is taken from GSE2457. Results The mean ratio of intracavernosal pressure/blood pressure for the CNI group (0.54±0.4 cmH2O) was significantly lower than that in the sham operation group (0.73±0.8 cmH2O, p<0.05). Supervised and unsupervised clustering analysis showed that the diabetes- and CNI-induced ED cavernous tissues had different gene expression profiles from normal cavernous tissues. We identified 46 genes that were upregulated and 77 genes that were downregulated in both the CNI- and diabetes-induced ED models. Conclusions Our genome-wide and computational studies provide the groundwork for understanding complex mechanisms and molecular signature changes in ED. PMID:27437539

  10. Percutaneous transsplenic portal catheterization combined with TIPS for the treatment of portal vein thrombosis associated with cavernous transformation

    International Nuclear Information System (INIS)

    Objective: To evaluate the feasibility, safety and efficacy of percutaneous transsplenic portal catheterization combined with transjugular intrahepatic portosystemic shunt (TIPS) in the treatment of portal vein thrombosis (PVT) associated with cavernous transformation. Methods: Percutaneous transsplenic portal catheterization was performed in 3 patients suffered from PVT with cavernous transformation in order to reopen the portal vein, then, TIPS was carried out to establish the portal shunt. A follow-up of 22-40 months period was conducted to observe therapeutic results, stent patency, hepatic function and complications. Results: The procedure was successfully completed in all three patients. One patient developed early symptoms of hepatic encephalopathy two times during the following 7 months, and the symptoms disappeared after medication was employed. In one patient the bilirubin was persistently increased in 6 months after the treatment, and there was no significant difference in the bilirubin level compared to that before the procedure. The remaining patient showed good recovery after the procedure. No complications occurred during the interventional management, and in a follow-up period of 22-40 months the shunt remained patency and no bleeding reoccurred. Conclusion: In treating the portal vein thrombosis associated with cavernous transformation, the choices of therapeutic methods are limited. Thus, as a safe and effective technique, percutaneous transsplenic portal catheterization combined with transjugular intrahepatic portosystemic shunt may be used clinically, although the procedure carries difficulties as well as challenges. (authors)

  11. Atypically enhancing hepatic cavernous hemangiomas: high-spatial-resolution gadolinium-enhanced triphasic dynamic gradient-recalled-echo imaging findings

    International Nuclear Information System (INIS)

    We retrospectively investigated the appearance and frequency of atypically enhancing cavernous hemangiomas with high-spatial-resolution (512 x 224 matrix) gadolinium-enhanced triphasic dynamic gradient-recalled-echo (GRE) MR images. Images of 132 hepatic cavernous hemangiomas (ranging in size from 4 to 72 mm; mean size 17.2 mm) in 95 patients (42 men and 53 women; age range 25-85 years; mean age 54 years) were retrospectively reviewed by two independent radiologists. Forty (30%) of 132 lesions atypically enhanced. Smaller hemangiomas (≤15 mm) more frequently (29%) showed early entire enhancement with or without arterio-portal shunting in the hepatic arterial-dominant phase (p<0.001); most of them showed hyperintense complete fill-in in the equilibrium phase and were readily characterized. ''Bright dot'' or minimal peripheral enhancement in the equilibrium phase was seen in a small number of lesions (6% each). With T2-weighted images, 130 (98%) lesions showed moderately to very high signal intensity and only 2 (2%) with minimal peripheral enhancement showed hyperintensity of slight degree. The high-spatial-resolution dynamic GRE images clearly revealed minute enhancement characteristics of hemangiomas. Although moderately to very high signal intensity with T2-weighted MR images is informative for the diagnosis of most cavernous hemangiomas, when a lesion shows minimal peripheral enhancement in the equilibrium phase and hyperintensity of slight degree with T2-weighted images, further follow-up or biopsy may be warranted to discriminate hypovascular metastases. (orig.)

  12. Blunt abdominal injury with rupture of giant hepatic cavernous hemangioma and laceration of the spleen

    Institute of Scientific and Technical Information of China (English)

    Lung-YunKang; Fong-DeeHuang; Yuan-YuarnLiu

    2015-01-01

     A 41-year-old woman with blunt abdominal trau-ma due to a motor vehicle accident presented to our emergency department. The patient had a history of a giant hepatic cavern-ous hemangioma. Emergency exploratory laparotomy was per-formed for suspected intra-abdominal bleeding with abdominal compartment syndrome, and more than 4 liters of blood and blood clots were removed. An active bleeding laceration (5 cm) of a hepatic cavernous hemangioma was detected in segment III of the liver. The bleeding was controlled by sutures, Teflon patches and tamponade. The abdomen was closed temporarily using the vacuum-assisted method. Because of the presence of persistent  fresh  blood  through  abdominal  drainage  at  a  rate of  >1  L/h,  splenectomy  was  performed  to  control  the  bleed-ing again by sutures and Teflon patches. Finally, the abdomen was closed using a biologic mesh. The patient was discharged home 30 days after trauma. Bleeding of trauma-caused hepatic hemangioma is rare, but splenic injury due to blunt abdominal trauma is common. An in-depth investigation is necessary to avoid second intervention.

  13. Possible role of the cavernous sinus veins in cerebrospinal fluid absorption

    Directory of Open Access Journals (Sweden)

    Koh Lena

    2007-04-01

    Full Text Available Abstract The purpose of this investigation was to enhance our understanding of cerebrospinal fluid (CSF absorption pathways. To achieve this, Microfil (a coloured silastic material was infused into the subarachnoid space (cisterna magna of sheep post mortem, and the relevant tissues examined macroscopically and microscopically. The Microfil was taken up by an extensive network of extracranial lymphatic vessels in the olfactory turbinates. In addition however, Microfil also passed consistently through the dura at the base of the brain. Microfil was noted in the spaces surrounding the venous network that comprises the cavernous sinus, in the adventitia of the internal carotid arteries and adjacent to the pituitary gland. Additionally, Microfil was observed within the endoneurial spaces of the trigeminal nerve and in lymphatic vessels emerging from the epineurium of the nerve. These results suggest several unconventional pathways by which CSF may be removed from the subarachnoid space. The movement of CSF to locations external to the cranium via these routes may lead to its absorption into veins and lymphatics outside of the skull. The physiological importance of these pathways requires further investigation.

  14. Discovery Mondays: 'The civil engineering genius of the 100-metre deep underground caverns'

    CERN Multimedia

    2004-01-01

    CERN is first and foremost a place where physicists study particle collisions. But to be able to observe the infinitely small, they need huge pieces of equipment, the accelerators and detectors, whose construction, some 100 metres below the earth's surface calls on the services of other fascinating disciplines. Take civil engineering, for example. For the construction of the LHC some 420 000 cubic metres of rock have had to be excavated for the 6500 metres of tunnel, 6 new shafts and 32 underground chambers and caverns. To avoid disrupting other experiments in progress, the work on these exceptional structures has had to be done without creating vibrations. The ATLAS experiment hall, a huge cathedral-like structure 100 metres below ground, is another mind-blowing feat of civil engineering. Its construction involved the use of ground-breaking technology, such as the system for suspending the ceiling put in place during the excavation work. At the next Discovery Monday, the specialists responsible for...

  15. Long term follow up of carotid cavernous fistula patients treated with carotid occlusion

    International Nuclear Information System (INIS)

    Objective: To explore efficacy,durability and possible impacts on life quality of carotid occlusion treatment to carotid cavernous fistula (CCF) patients. Methods: CCF patients since 2001 were retrospectively analyzed, the clinical features, 2 weeks post procedure mRS score and ratio of carotid occlusion were recorded. Headache impact test (HIT-6) and Short form health survey (SF-36) were used to assess impact of sequelae in patients' daily life, by phone call, questionnaire and clinic recheck. Results: Total 96 cases were studied composed of 81 direct CCF and 15 dural AVF. Thirty-two direct CCF cases underwent carotid occlusion during procedure and many ophthalmologic signs but visual impairment got recovery after 2 weeks, the mRS score less than 2 were revealed. The one year post operation HIT-6 score more than 50 was more likely found in carotid occlusion cases comparing with those preserved carotid artery while the 3 year SF-36 scores of carotid occlusion cases revealed inferior to those with patent artery, especially in body pain, general health and vitality subscales. Conclusion: Carotid occlusion seems to be a feasible, effective and durable alternative for CCF treatment, but which could play a negative role on quality of patients' life in the long run. (authors)

  16. Sporadic Cerebral Cavernous Malformations: Report of Further Mutations of CCM Genes in 40 Italian Patients

    Science.gov (United States)

    D'Angelo, Rosalia; Alafaci, Concetta; Scimone, Concetta; Ruggeri, Alessia; Salpietro, Francesco Maria; Bramanti, Placido; Tomasello, Francesco; Sidoti, Antonina

    2013-01-01

    Cerebral cavernous malformations (CCMs) are vascular lesions characterized by abnormally enlarged capillary cavities, affecting the central nervous system. CCMs can occur sporadically or as a familial autosomal dominant condition with incomplete penetrance and variable clinical expression attributable to mutations in three different genes: CCM1 (K-Rev interaction trapped 1 (KRIT1)), CCM2 (MGC4607), and CCM3 (PDCD10). CCMs occur as a single or multiple malformations that can lead to seizures, focal neurological deficits, hemorrhagic stroke, and headache. However, patients are frequently asymptomatic. In our previous mutation screening, performed in a cohort of 95 Italian patients, both sporadic and familial, we have identified several mutations in CCM genes, three of which in three distinct sporadic patients. In this study, representing further molecular screening of the three CCM genes, in a south Italian cohort of CCM patients enrolled by us in the last three years, we report the identification of other four new mutations in 40 sporadic patients with either single or multiple CCM. PMID:24058906

  17. Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Oriana S. [Yale Univ., New Haven, CT (United States); Deng, Hanqiang [Shanghai Jiao Tong Univ. School of Medicine (SJTU-SM), Shanghai (China); Liu, Dou [Yale Univ. School of Medicine, New Haven, CT (United States); Zhang, Ya [Yale Univ. School of Medicine, New Haven, CT (United States); Wei, Rong [Shanghai Jiao Tong Univ. School of Medicine (SJTU-SM), Shanghai (China); Deng, Yong [Yale Univ. School of Medicine, New Haven, CT (United States); Zhang, Fan [Yale Univ. School of Medicine, New Haven, CT (United States); Louvi, Angeliki [Yale Univ. School of Medicine, New Haven, CT (United States); Turk, Benjamin E. [Yale Univ., New Haven, CT (United States); Boggon, Titus J. [Yale Univ., New Haven, CT (United States); Su, Bing [Shanghai Jiao Tong Univ. School of Medicine (SJTU-SM), Shanghai (China)

    2015-08-03

    Cerebral cavernous malformations 2 (CCM2) loss is associated with the familial form of CCM disease. The protein kinase MEKK3 (MAP3K3) is essential for embryonic angiogenesis in mice and interacts physically with CCM2, but how this interaction is mediated and its relevance to cerebral vasculature are unknown. Here we report that Mekk3 plays an intrinsic role in embryonic vascular development. Inducible endothelial Mekk3 knockout in neonatal mice is lethal due to multiple intracranial haemorrhages and brain blood vessels leakage. We discover direct interaction between CCM2 harmonin homology domain (HHD) and the N terminus of MEKK3, and determine a 2.35 Å cocrystal structure. We find Mekk3 deficiency impairs neurovascular integrity, which is partially dependent on Rho–ROCK signalling, and that disruption of MEKK3:CCM2 interaction leads to similar neurovascular leakage. We conclude that CCM2:MEKK3-mediated regulation of Rho signalling is required for maintenance of neurovascular integrity, unravelling a mechanism by which CCM2 loss leads to disease.

  18. Stabiliztin of VEGFR2 Signaling by Cerebral Cavernous Malformation 3 is Critical for Vascular Development

    Energy Technology Data Exchange (ETDEWEB)

    Y He; H Zhang; L Yu; M Gunel; T Boggon; H Chen; W Min

    2011-12-31

    Cerebral cavernous malformations (CCMs) are human vascular malformations caused by mutations in three genes of unknown function: CCM1, CCM2, and CCM3. CCM3, also known as PDCD10 (programmed cell death 10), was initially identified as a messenger RNA whose abundance was induced by apoptotic stimuli in vitro. However, the in vivo function of CCM3 has not been determined. Here, we describe mice with a deletion of the CCM3 gene either ubiquitously or specifically in the vascular endothelium, smooth muscle cells, or neurons. Mice with global or endothelial cell-specific deletion of CCM3 exhibited defects in embryonic angiogenesis and died at an early embryonic stage. CCM3 deletion reduced vascular endothelial growth factor receptor 2 (VEGFR2) signaling in embryos and endothelial cells. In response to VEGF stimulation, CCM3 was recruited to and stabilized VEGFR2, and the carboxyl-terminal domain of CCM3 was required for the stabilization of VEGFR2. Indeed, the CCM3 mutants found in human patients lacking the carboxyl-terminal domain were labile and were unable to stabilize and activate VEGFR2. These results demonstrate that CCM3 promotes VEGFR2 signaling during vascular development.

  19. Dynamic Response Analysis of Leaching Tube Used in Salt Cavern Gas Storage

    Directory of Open Access Journals (Sweden)

    Tongtao Wang

    2012-09-01

    Full Text Available Fluid-structure coupling finite element model is proposed to analysis the dynamic response of leaching tube in the construction of salt cavern gas storage. The stress and deformation of leaching tube induced by the carrying fluid flow are studied. Meanwhile, an experiment on the dynamic response of plastic tube caused by carrying fluid flow is carried out to verify the calculation accuracy of the proposed model. Experimental results prove that the finite element model proposed in the study has a high accuracy, which can well characterize the stress and deformation of leaching tube under the action of fluid flow. The errors between experimental and numerical results are about 5%, which can satisfy the engineering accuracy demands. Excited pressure produced by fluid flow has significant effects on the stress and deformation of leaching tube string, which is the main cause of tube damage. Therefore, low injected freshwater velocity is proposed at the initial stage and then it is increased slowly. Moreover, rapidly opening or closing the valve should be avoided.

  20. Installation of the Liquid Argon Calorimater Barrel in the ATLAS Experimental Cavern

    CERN Multimedia

    Vandoni, G.

    On the 27th of October, the Liquid Argon Barrel cryostat was transported from Building 180 to point 1. The next day, the Barrel was lowered into the cavern, and was placed on jacks close to its final position inside the completed lower half of the Tile calorimeter. After a day of precise adjustment, it was resting within a few millimetres of its nominal final position, waiting for the upper half of the Tile calorimeter to be installed. Tight requests had been issued by the Liquid Argon collaboration for the whole transport. It was foreseen that the cryostat should not see any acceleration larger than 0.15g along its axis, 0.08g transversally and 0.3g in the vertical direction. In addition, no acceleration higher than 0.03g (or even 0.003g for permanent oscillation) would be allowed at 20Hz, to avoid the risk of damaging the absorbers at this spontaneous vibration frequency. The difficulty would arise when coping these demands with the tortuous route, its slopes and curbs, vibration transmission from the engi...

  1. Gamma radiosurgery combined with trans-sphenoidal surgery for pituitary tumor involved to the cavernous sinus

    International Nuclear Information System (INIS)

    Ten patients (2 males and 8 females with an average age of 39 years) were treated with combined trans-sphenoidal surgery and gamma radiosurgery for pituitary tumor involved to the cavernous sinus. A Follow-up period ranged from 7 to 29 months, with a mean of 21 months. Therapeutic effects were assessed using magnetic resonance imaging (MRI) every 3 months, endocrine examination, optical examination for visual field, and auditory test. Pituitary tumor after radiosurgery was shown as hypointensity on T1-weighted images and hyperintensity on T2-weighted images. Tumor response could be classified on MRI into (1) a remarkably decreased tumor in size with increased contrast enhancement (n=6), (2) a remarkably decreased tumor in size with unchanged contrast enhancement (n=one), (3) a slightly decreased tumor in size with increased spotted contrast enhancement (n=2), and (4) unchanged tumor in size with decreased contrast enhancement (n=one). Of 6 Type 1 patients, 5 had growth hormone production. Growth hormone production tended to be associated with favorable response to radiosurgery. In 3 patients who showed endocrinologically favorable response (such as increased growth hormone in blood and somatomedin C value), complete regression of tumor was achieved at a 20-month follow-up period. Radiosurgery also seemed to be useful for treating hormone active tumors. (N.K.)

  2. The application of 99Tcm-RBC scintigraphy in the diagnosis of orbital cavernous hemangioma

    International Nuclear Information System (INIS)

    Objective: The purpose of this study was to evaluate the clinical value of 99Tcm-RBC scintigraphy in the diagnosis of orbital cavernous hemangioma (OCH). Methods: Forty-one patients with pathologically confirmed orbital mass, of which 10 were OCH, underwent 99Tcm-RBC scintigraphy in this study. The scanning procedure included an initial perfusion phase, followed by an early and a delayed blood pool phase. All patients underwent ultrasonography and CT, and 15 patients also underwent MRI. SPSS 11.5 was used to analyse the data. Results: All 10 OCH patients had no abnormal findings on radionuclide angiographic images and early blood pool phase, but increased activity was found during delayed blood pool phase. All the other non-OCH orbital tumors did not have this tracer pattern. The radioactivity ratios of the lump to non-lump (L/N) were 2.96 ± 0.05 and 1.14 ± 0.25, respectively, which had a statistically significant difference (t=15.18, P99Tcm- RBC scintigraphy is a reliable and useful procedure for the diagnosis of OCH. It may be considered as one of the routine clinical screening tools for the diagnosis of OCH and as a complement investigation to ultrasonography and CT. (authors)

  3. Role of oxidative stress in surgical cavernous nerve injury in a rat model.

    Science.gov (United States)

    Wang, Hui; Ding, Xie-Gang; Li, Shi-Wen; Zheng, Hang; Zheng, Xin-Min; Navin, Shrestha; Li, Lu; Wang, Xing-Huan

    2015-06-01

    This study investigates the role of oxidative stress in surgical cavernous nerve (CN) injury in a rat model. Eighty-four male Sprague-Dawley rats were randomly divided into three groups: group 1, sham-operated rats; group 2, bilateral CN-crushed rats; and group 3, bilateral CN-transection-and-sutured-immediately rats. Oxidative stress was evaluated by malondialdehyde levels, super oxide dismutase (SOD) activities, and glutathione peroxidase (GPX) activities in serum. Erectile function was assessed by CN electrostimulation at 3 months with mean maximal intracavernous pressure (ICP) and maximal ICP per mean arterial pressure. Nerve injury was assessed by toluidine blue staining of CNs and nicotinamide adenine dinucleotide phosphate (NADPH)-diaphorase staining of penile tissue. GPX protein expression and nitrotyrosine-3 (NT-3) levels in penile tissue were measured. Erectile function and the number of myelinated axons of CNs and NADPH-diaphorase-positive nerve fibers were statistically decreased between groups, from sham to crush to transection. For markers, both nerve-injury groups showed increased oxidative stress markers at early time points, with the transection group showing greater oxidative stress than the crushed group and values normalizing to sham levels by week 12. GPX expression and NT-3 levels in penile tissue were in concordance with the results of SOD and GPX. These results show that oxidative stress plays an important role in injured CNs, and different methods of CN injury can lead to different degrees of oxidative stress in a rat model. PMID:25597854

  4. Research on base rock mechanic characteristics of caverns for radioactive waste disposal

    International Nuclear Information System (INIS)

    It has been considered that underground space is mechanically stable as compared with on the ground, and superior for storing radioactive waste for long period. However, in order to utilize underground space for the place of radioactive waste disposal, its long term stability such as the aseismatic ability of base rocks must be ensured, and for this purpose, it is necessary to grasp the mechanical characteristics of the base rocks around caverns, and to advance the technology for measuring and evaluating minute deformation and earth pressure change. In this research, the study on the fracture mechanics characteristics of base rocks and the development of the technology for measuring long terms stress change of base rocks were carried out. In this research, what degree the memory of past stress is maintained by rocks was presumed by measuring AE and strain when stress was applied to rock test pieces. The rocks tested were tuff, sandstone and granite. The experimental method and the experimental results of the prestress by AE method and DRA are reported. (K.I.)

  5. Recognition of microclimate zones through radon mapping, Lechuguilla Cave, Carlsbad Caverns National Park, New Mexico

    International Nuclear Information System (INIS)

    Radon concentrations range from less than 185 to 3,515 Bq m-3 throughout Lechuguilla Cave, Carlsbad Caverns National Park, New Mexico. Concentrations in the entrance passages and areas immediately adjacent to these passages are controlled by outside air temperature and barometric pressure, similar to other Type 2 caves. Most of the cave is developed in three geographic branches beneath the entrance passages; these areas maintain Rn levels independent of surface effects, an indication that Rn levels in deep, complex caves or mines cannot be simply estimated by outside atmospheric parameters. These deeper, more isolated areas are subject to convective ventilation driven by temperature differences along the 477-m vertical extent of the cave. Radon concentrations are used to delineate six microclimate zones (air circulation cells) throughout the cave in conjunction with observed airflow data. Suspected surface connections contribute fresh air to remote cave areas demonstrated by anomalous Rn lows surrounded by higher values, the presence of mammalian skeletal remains, CO2 concentrations and temperatures lower than the cave mean, and associated surficial karst features

  6. Surrounding rock deformation analysis of underground caverns with multi-body finite element method

    Directory of Open Access Journals (Sweden)

    Wan-jin LIANG

    2009-09-01

    Full Text Available Discontinuous deformation problems are common in rock engineering. Numerical analysis methods based on system models of the discrete body can better solve these problems. One of the most effective solutions is discontinuous deformation analysis (DDA method, but the DDA method brings about rock embedding problems when it uses the strain assumption in elastic deformation and adopts virtual springs to simulate the contact problems. The multi-body finite element method (FEM proposed in this paper can solve the problems of contact and deformation of blocks very well because it integrates the FEM and multi-body system dynamics theory. It is therefore a complete method for solving discontinuous deformation problems through balance equations of the contact surface and for simulating the displacement of whole blocks. In this study, this method was successfully used for deformation analysis of underground caverns in stratified rock. The simulation results indicate that the multi-body FEM can show contact forces and the stress states on contact surfaces better than DDA, and that the results calculated with the multi-body FEM are more consistent with engineering practice than those calculated with DDA method.

  7. Effects of vascular endothelial growth factor on angiogenesis of the endothelial cells isolated from cavernous malformations

    Institute of Scientific and Technical Information of China (English)

    TAN YuZhen; ZHAO Yao; WANG HaiJie; ZHOU LiangFu; MAO Ying; LIU Rui; SHU Jia; WANG YongFei

    2008-01-01

    Human cerebral cavernous malformation (CM) is a common vascular malformation of the central nervous system. We have investigated the biological characteristics of CM endothelial cells and the cellular and molecular mechanisms of CM angiogenesis to offer new insights into exploring effective measures for treatment of this disease. The endothelial cells were isolated from CM tissue masses dissected during operation and expanded in vitro. Expression of VEGFR-1 and VEGFR-2 was examined with immunocytochemical staining. Proliferation, migration and tube formation of CM endothelial cells were determined using MTT, wounding and transmigration assays, and three-dimensional collagen type Ⅰ gel respectively. The endothelial cells were successfully isolated from the tissue specimens of 25 CMs dissected without dipolar electrocoagulation. The cells show the general characteristics of the vascular endothelial cells. Expression of VEGFR-1 and VEGFR-2 on the cells is higher than that on the normal cerebral microvascular endothelial cells. After treatment with VEGF, numbers of the proliferated and migrated cells, the maximal distance of cell migration and the length and area of capillary-like struc-tures formed in the three-dimensional collagen gel increase significantly. These results demonstrate that expression of VEGFR-1 and VEGFR-2 on CM endothelial cells is up-regulated. By binding to re-ceptors, VEGF may activate the downstream signaling pathways and promote proliferation, migration and tube formation of CM endothelial cells. VEGF/VEGFR signaling pathways play important regulating roles in CM angiogenesis.

  8. FAM222B Is Not a Likely Novel Candidate Gene for Cerebral Cavernous Malformations.

    Science.gov (United States)

    Spiegler, Stefanie; Kirchmaier, Bettina; Rath, Matthias; Korenke, G Christoph; Tetzlaff, Fabian; van de Vorst, Maartje; Neveling, Kornelia; Acker-Palmer, Amparo; Kuss, Andreas W; Gilissen, Christian; Fischer, Andreas; Schulte-Merker, Stefan; Felbor, Ute

    2016-07-01

    Cerebral cavernous malformations (CCMs) are prevalent slow-flow vascular lesions which harbour the risk to develop intracranial haemorrhages, focal neurological deficits, and epileptic seizures. Autosomal dominantly inherited CCMs were found to be associated with heterozygous inactivating mutations in 3 genes, CCM1 (KRIT1), CCM2 (MGC4607), and CCM3 (PDCD10) in 1999, 2003 and 2005, respectively. Despite the availability of high-throughput sequencing techniques, no further CCM gene has been published since. Here, we report on the identification of an autosomal dominantly inherited frameshift mutation in a gene of thus far unknown function, FAM222B (C17orf63), through exome sequencing of CCM patients mutation-negative for CCM1-3. A yeast 2-hybrid screen revealed interactions of FAM222B with the tubulin cytoskeleton and STAMBP which is known to be associated with microcephaly-capillary malformation syndrome. However, a phenotype similar to existing models was not found, neither in fam222bb/fam222ba double mutant zebrafish generated by transcription activator-like effector nucleases nor in an in vitro sprouting assay using human umbilical vein endothelial cells transfected with siRNA against FAM222B. These observations led to the assumption that aberrant FAM222B is not involved in the formation of CCMs. PMID:27587990

  9. CT angiography diagnosis on the rupture of traumatic pseudoaneurysms of the cavernous of the internal carotid artery into the sphenoid sinus

    International Nuclear Information System (INIS)

    Objective: To investigate diagnostic value of CTA for traumatic pseudoaneurysms (TPA) in the cavernous segment of the internal carotid artery (ICA) when they rupture into the sphenoid sinus. Methods: CTA of 7 patients with TPA in the cavernous segments of ICA verified by DSA were retrospectively analyzed. All the patients were performed CTA scanning. The post-processing techniques included VR, MIP, MPR, and CPR. Results: All the CTA images of 7 patients showed irregular mass in the sphenoid sinus with obviously enhancement in the same phase to ICA, which communicating with ICA in wide base. The peripheral area of the mass showed no enhancement. The size varied from 3 mm × 2 mm × 1 mm to 33 mm × 30 mm × 27 mm. The adjacent lateral wall of sphenoid sinus showed fractures in all cases. TPA located at anterior-knee segments of cavernous ICA in 6 cases, and cavernous free segment in 1 case. All the disruptions were found at medial or anterior medial wall of ICA. Conclusions: Cranial CTA is the effective non-invasive method for diagnosing TPA in the cavernous segment of ICA when they rupture into sphenoid sinus. Combined using of VR, MIP, MPR, and CPR can delineate the location and size of the sphenoid wall fracture and the ICA rupture, which help to clarify the anatomical relationship between them. (authors)

  10. Multiple cerebral cavernous malformations: typical pattern on MR imaging and appearance of a new lesion in the follow-up MRI

    International Nuclear Information System (INIS)

    Cerebral cavernous malformations (CCM) are common, mostly benign vascular anomalies of the CNS. Clinical features are seizures, headache and focal neurological signs. Often they are asymptomatic. Apart from sporadically cases CCM occur as an autosomal dominant condition. Familial cases are associated with a high frequency of multiple lesions. MRI is most sensitive in the detection of cavernous malformations. The MRI findings of CCM are variable, depending on hemorrhage and calcifications. The typical appearance of CCM are heterogenous ''popcorn-like'' lesions of different size with a mixed signal core and a hypointense hemosiderin rim. Our report concerns a 22 year old man with multiple cerebral cavernous malformations whose follow-up MRI of brain showed the appearance of a new lesion. (orig.)

  11. Ovarian Cavernous Hemangioma Presenting as a Large Growing Mass in a Postmenopausal Woman: A Case Report and Review of the Literature.

    Science.gov (United States)

    Kim, Sun Suk; Han, Si Eun; Lee, Nam Kyung; Choi, Kyung Un; Joo, Jong Kil; Suh, Dong Soo; Kim, Heung Yeol; Kim, Ki Hyung

    2015-12-01

    Ovarian hemangiomas are usually of the cavernous type, and are rarely encountered. A 73-year-old woman presented with lower abdominal discomfort. Subsequent physical examination depicted a palpable mass in the lower abdomen. Abdominopelvic computed tomography (CT) revealed a well-circumscribed mass with thin septa measuring 12.1 × 9.0 cm in the right ovary. Levels of the tumor markers cancer antigen (CA)-125 and CA 19-9 were within the normal range. At laparoscopy, the tumor was found to be confined to the right ovary and to have a smooth surface. The final histopathological result was ovarian cavernous hemangioma. Microscopically, the mass consisted of multiple, dilated, blood-filled vascular channels separated by loose connective tissue, and all were lined by a single layer of flattened endothelium. The authors present a case of ovarian cavernous hemangioma presenting as a large growing mass in a postmenopausal woman and review previously published literature. PMID:26793681

  12. Cavernous hemangioma of the internal auditory canal encasing the VII and VIII cranial nerve complex: case report and review of the literature.

    Science.gov (United States)

    Mastronardi, Luciano; Carpineta, Ettore; Cacciotti, Guglielmo; Di Scipio, Ettore; Roperto, Raffaelino

    2016-04-01

    Cavernous angiomas originating in the internal auditory canal are very rare. In the available literature, only 65 cases of cavernomas in this location have been previously reported. We describe the case of a 22-year-old woman surgically treated for a cavernous hemangioma in the left internal auditory canal, mimicking on preoperative magnetic resonance imaging MRI an acoustic neuroma. Neurological symptoms were hypoacusia and dizziness. The cavernous angioma encased the seventh and, partially, the eighth cranial nerve complex. A "nearly total" removal was performed, leaving a thin residual of malformation adherent to the facial nerve. Postoperative period was uneventful; hearing was unchanged, but the patient had a moderate inferior left facial palsy (House-Brackmann grade II) slightly improved during the following weeks. On the basis of the observation of this uncommon case, we propose a revision of the literature and discuss clinical features, differential diagnosis, and treatment. PMID:26876892

  13. Modeling of coupled thermodynamic and geomechanical performance of underground compressed air energy storage (CAES) in lined rock caverns

    Energy Technology Data Exchange (ETDEWEB)

    Rutqvist, J.; Kim, H. -M.; Ryu, D. -W.; Synn, J. -H.; Song, W. -K.

    2012-02-01

    We applied coupled nonisothermal, multiphase fluid flow and geomechanical numerical modeling to study the coupled thermodynamic and geomechanical performance of underground compressed air energy storage (CAES) in concrete-lined rock caverns. The paper focuses on CAES in lined caverns at relatively shallow depth (e.g., 100 m depth) in which a typical CAES operational pressure of 5 to 8 MPa is significantly higher than both ambient fluid pressure and in situ stress. We simulated a storage operation that included cyclic compression and decompression of air in the cavern, and investigated how pressure, temperature and stress evolve over several months of operation. We analyzed two different lining options, both with a 50 cm thick low permeability concrete lining, but in one case with an internal synthetic seal such as steel or rubber. For our simulated CAES system, the thermodynamic analysis showed that 96.7% of the energy injected during compression could be recovered during subsequent decompression, while 3.3% of the energy was lost by heat conduction to the surrounding media. Our geomechanical analysis showed that tensile effective stresses as high as 8 MPa could develop in the lining as a result of the air pressure exerted on the inner surface of the lining, whereas thermal stresses were relatively smaller and compressive. With the option of an internal synthetic seal, the maximum effective tensile stress was reduced from 8 to 5 MPa, but was still in substantial tension. We performed one simulation in which the tensile tangential stresses resulted in radial cracks and air leakage though the lining. This air leakage, however, was minor (about 0.16% of the air mass loss from one daily compression) in terms of CAES operational efficiency, and did not significantly impact the overall energy balance of the system. However, despite being minor in terms of energy balance, the air leakage resulted in a distinct pressure increase in the surrounding rock that could be

  14. SU-E-I-91: Quantitative Assessment of Early Hepatocellular Carcinoma and Cavernous Hemangioma of Live Using In-Line Phase-Contrast X-Ray Imaging

    International Nuclear Information System (INIS)

    Purpose: To investigate the potential utility of in-line phase-contrast imaging (ILPCI) technique with synchrotron radiation in detecting early hepatocellular carcinoma and cavernous hemangioma of live using in vitro model system. Methods: Without contrast agents, three typical early hepatocellular carcinoma specimens and three typical cavernous hemangioma of live specimens were imaged using ILPCI. To quantitatively discriminate early hepatocellular carcinoma tissues and cavernous hemangioma tissues, the projection images texture feature based on gray level co-occurrence matrix (GLCM) were extracted. The texture parameters of energy, inertia, entropy, correlation, sum average, sum entropy, difference average, difference entropy and inverse difference moment, were obtained respectively. Results: In the ILPCI planar images of early hepatocellular carcinoma specimens, vessel trees were clearly visualized on the micrometer scale. Obvious distortion deformation was presented, and the vessel mostly appeared as a ‘dry stick’. Liver textures appeared not regularly. In the ILPCI planar images of cavernous hemangioma of live specimens, typical vessels had not been found compared with the early hepatocellular carcinoma planar images. The planar images of cavernous hemangioma of live specimens clearly displayed the dilated hepatic sinusoids with the diameter of less than 100 microns, but all of them were overlapped with each other. The texture parameters of energy, inertia, entropy, correlation, sum average, sum entropy, and difference average, showed a statistically significant between the two types specimens image (P<0.01), except the texture parameters of difference entropy and inverse difference moment(P>0.01). Conclusion: The results indicate that there are obvious changes in morphological levels including vessel structures and liver textures. The study proves that this imaging technique has a potential value in evaluating early hepatocellular carcinoma and cavernous

  15. An Analytical Solution for Mechanical Responses Induced by Temperature and Air Pressure in a Lined Rock Cavern for Underground Compressed Air Energy Storage

    Science.gov (United States)

    Zhou, Shu-Wei; Xia, Cai-Chu; Du, Shi-Gui; Zhang, Ping-Yang; Zhou, Yu

    2015-03-01

    Mechanical responses induced by temperature and air pressure significantly affect the stability and durability of underground compressed air energy storage (CAES) in a lined rock cavern. An analytical solution for evaluating such responses is, thus, proposed in this paper. The lined cavern of interest consists of three layers, namely, a sealing layer, a concrete lining and the host rock. Governing equations for cavern temperature and air pressure, which involve heat transfer between the air and surrounding layers, are established first. Then, Laplace transform and superposition principle are applied to obtain the temperature around the lined cavern and the air pressure during the operational period. Afterwards, a thermo-elastic axisymmetrical model is used to analytically determine the stress and displacement variations induced by temperature and air pressure. The developments of temperature, displacement and stress during a typical operational cycle are discussed on the basis of the proposed approach. The approach is subsequently verified with a coupled compressed air and thermo-mechanical numerical simulation and by a previous study on temperature. Finally, the influence of temperature on total stress and displacement and the impact of the heat transfer coefficient are discussed. This paper shows that the temperature sharply fluctuates only on the sealing layer and the concrete lining. The resulting tensile hoop stresses on the sealing layer and concrete lining are considerably large in comparison with the initial air pressure. Moreover, temperature has a non-negligible effect on the lined cavern for underground compressed air storage. Meanwhile, temperature has a greater effect on hoop and longitudinal stress than on radial stress and displacement. In addition, the heat transfer coefficient affects the cavern stress to a higher degree than the displacement.

  16. Dsa examination and diagnosis of arteriovenous shunts in hepatic cavernous hemangiomas of adults

    International Nuclear Information System (INIS)

    Objective: To correct the misunderstanding that arteriovenous shunts (AVS) are rarely found in adult cavernous hemangiomas of the liver (CHL) and to increase its diagnosis rate by DSA. Methods: DSA examination and DSA images of thirty adults with definitely diagnostic CHL and without evidence of other hepatic diseases and hepatic injury were analyzed retrospectively. X-ray films of 21 cases with AVS taken immediately after transcatheter arterial embolization using lipiodol (L-TAE) were compared with the corresponding DSA images to check up those AVS opacified in DSA by observing sediment and distribution of iodized oil injected. Results: Definite diagnosis of AVS by DSA were obtained in 22 cases of this series (73%). All the AVS were located in the peritumoral parenchyma and appeared as parallel track sign, and early opacification of small draining veins, etc. during arterial phase of DSA. X-ray films taken immediately after L-TAE in 21 of 22 cases with AVS showed that few portal radicles or draining veins were refilled by iodized oil through incompletely occluded shunts in 11 cases, and no any vein was refilled by iodized oil resulted from complete occlusion of the present AVS in 10. No definite AVS was found in the other 8 cases of this series, and in 6 of them improper imaging factors of DSA were used. Conclusion: This study serves to emphasize that AVS is not a diagnosis of hepatic malignancy, but is frequently seen in the commonly benign CHL of adults. Proper imaging factors of DSA and superior images can be helpful to opacify small AVS of CHL. The formation of AVS in CHL may be closely related to the pathological changes of peritumoral parenchyma, however, its mechanism must be further studied

  17. Cranial Nerve Dysfunction Associated with Cavernous Dural Arteriovenous Fistulas After Transvenous Embolization with Onyx

    International Nuclear Information System (INIS)

    PurposeCranial nerve dysfunction (CND) is not uncommon in patients with cavernous dural arteriovenous fistulas (cDAVFs), and may represent an initial manifestation or a complication after endovascular treatment. This study evaluated the outcome of CND associated with cDAVFs after transvenous embolization (TVE) using Onyx.Materials and MethodsForty-one patients with cDAVFs were treated with TVE in our department between April 2009 and October 2013. For each patient, clinical and radiologic records were retrospectively reviewed and evaluated, with an emphasis placed on evaluating the outcomes of the pre-existing cDAVF-induced CND and the TVE-induced CND.ResultsOf the 41 cases, 25 had a history of preoperative CND. Postoperatively, gradual remission to complete recovery (CR) within 8 months was observed in 17 of these cases, transient aggravation in 7, and significant improvement to be better than preoperative function but no CR in 1. All aggravation of CND occurred immediately or within 1 day after TVE and resolved completely within 5 months. Nine patients developed new CND after TVE. New CND occurred during the perioperative period in 8 cases, but all cases resolved completely within 15 days–6 months. Delayed CND was observed in 3 cases with a time lag of 3–25 months after TVE. Two of these completely resolved within 20 days–1 month and the remaining case significantly improved.ConclusionBoth the pre-existing cDAVF-induced CND and the TVE-induced new or aggravated CND completely resolved in almost all cases after embolization with Onyx

  18. Long-Term Outcomes of Stereotactic Radiosurgery for Treatment of Cavernous Sinus Meningiomas

    International Nuclear Information System (INIS)

    Purpose: Patients with cavernous sinus meningiomas (CSM) have an elevated risk of surgical morbidity and mortality. Recurrence is often observed after partial resection. Stereotactic radiosurgery (SRS), either alone or combined with surgery, represents an important advance in CSM management, but long-term results are lacking. Methods and Materials: A total of 88 CSM patients, treated from January 1991 to December 2005, were retrospectively reviewed. The mean follow-up was 86.8 months (range, 17.1–179.4 months). Among the patients, 22 were followed for more than 10 years. There was a female predominance (84.1%). The age varied from 16 to 90 years (mean, 51.6). In all, 47 patients (53.4%) received SRS alone, and 41 patients (46.6%) had undergone surgery before SRS. A dose of 14 Gy was prescribed to isodose curves from 50% to 90%. In 25 patients (28.4%), as a result of the proximity to organs at risk, the prescribed dose did not completely cover the target. Results: After SRS, 65 (73.8%) patients presented with tumor volume reduction; 14 (15.9%) remained stable, and 9 (10.2%) had tumor progression. The progression-free survival was 92.5% at 5 years, and 82.5% at 10 years. Age, sex, maximal diameter of the treated tumor, previous surgery, and complete target coverage did not show significant associations with prognosis. Among the 88 treated patients, 17 experienced morbidity that was related to SRS, and 6 of these patients spontaneously recovered. Conclusions: SRS is an effective and safe treatment for CSM, feasible either in the primary or the postsurgical setting. Incomplete coverage of the target did not worsen outcomes. More than 80% of the patients remained free of disease progression during long-term follow-up.

  19. Long-Term Outcomes of Stereotactic Radiosurgery for Treatment of Cavernous Sinus Meningiomas

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Marcos Antonio dos, E-mail: marcosrxt@gmail.com [Radiotherapy Department, Instituto Madrileno de Oncologia/Grupo IMO, Madrid (Spain); Bustos Perez de Salcedo, Jose; Gutierrez Diaz, Jose Angel [Radiotherapy Department, Instituto Madrileno de Oncologia/Grupo IMO, Madrid (Spain); Neurosurgery Department, Sanatorio San Francisco de Asis, Madrid (Spain); Calvo, Felipe A. [Radiotherapy Department, Instituto Madrileno de Oncologia/Grupo IMO, Madrid (Spain); Department of Oncology, Hospital General Universitario Gregorio Maranon, Madrid (Spain); Samblas, Jose [Radiotherapy Department, Instituto Madrileno de Oncologia/Grupo IMO, Madrid (Spain); Neurosurgery Department, Sanatorio San Francisco de Asis, Madrid (Spain); Marsiglia, Hugo [Radiotherapy Department, Instituto Madrileno de Oncologia/Grupo IMO, Madrid (Spain); Sallabanda, Kita [Radiotherapy Department, Instituto Madrileno de Oncologia/Grupo IMO, Madrid (Spain); Neurosurgery Department, Sanatorio San Francisco de Asis, Madrid (Spain)

    2011-12-01

    Purpose: Patients with cavernous sinus meningiomas (CSM) have an elevated risk of surgical morbidity and mortality. Recurrence is often observed after partial resection. Stereotactic radiosurgery (SRS), either alone or combined with surgery, represents an important advance in CSM management, but long-term results are lacking. Methods and Materials: A total of 88 CSM patients, treated from January 1991 to December 2005, were retrospectively reviewed. The mean follow-up was 86.8 months (range, 17.1-179.4 months). Among the patients, 22 were followed for more than 10 years. There was a female predominance (84.1%). The age varied from 16 to 90 years (mean, 51.6). In all, 47 patients (53.4%) received SRS alone, and 41 patients (46.6%) had undergone surgery before SRS. A dose of 14 Gy was prescribed to isodose curves from 50% to 90%. In 25 patients (28.4%), as a result of the proximity to organs at risk, the prescribed dose did not completely cover the target. Results: After SRS, 65 (73.8%) patients presented with tumor volume reduction; 14 (15.9%) remained stable, and 9 (10.2%) had tumor progression. The progression-free survival was 92.5% at 5 years, and 82.5% at 10 years. Age, sex, maximal diameter of the treated tumor, previous surgery, and complete target coverage did not show significant associations with prognosis. Among the 88 treated patients, 17 experienced morbidity that was related to SRS, and 6 of these patients spontaneously recovered. Conclusions: SRS is an effective and safe treatment for CSM, feasible either in the primary or the postsurgical setting. Incomplete coverage of the target did not worsen outcomes. More than 80% of the patients remained free of disease progression during long-term follow-up.

  20. Cranial Nerve Dysfunction Associated with Cavernous Dural Arteriovenous Fistulas After Transvenous Embolization with Onyx

    Energy Technology Data Exchange (ETDEWEB)

    Li, Chuanhui; Wang, Yang; Li, Youxiang; Jiang, Chuhan; Wu, Zhongxue; Yang, Xinjian, E-mail: yang-xj@163.net [Capital Medical University, Beijing Neurosurgical Institute and Beijing Tiantan Hospital (China)

    2015-10-15

    PurposeCranial nerve dysfunction (CND) is not uncommon in patients with cavernous dural arteriovenous fistulas (cDAVFs), and may represent an initial manifestation or a complication after endovascular treatment. This study evaluated the outcome of CND associated with cDAVFs after transvenous embolization (TVE) using Onyx.Materials and MethodsForty-one patients with cDAVFs were treated with TVE in our department between April 2009 and October 2013. For each patient, clinical and radiologic records were retrospectively reviewed and evaluated, with an emphasis placed on evaluating the outcomes of the pre-existing cDAVF-induced CND and the TVE-induced CND.ResultsOf the 41 cases, 25 had a history of preoperative CND. Postoperatively, gradual remission to complete recovery (CR) within 8 months was observed in 17 of these cases, transient aggravation in 7, and significant improvement to be better than preoperative function but no CR in 1. All aggravation of CND occurred immediately or within 1 day after TVE and resolved completely within 5 months. Nine patients developed new CND after TVE. New CND occurred during the perioperative period in 8 cases, but all cases resolved completely within 15 days–6 months. Delayed CND was observed in 3 cases with a time lag of 3–25 months after TVE. Two of these completely resolved within 20 days–1 month and the remaining case significantly improved.ConclusionBoth the pre-existing cDAVF-induced CND and the TVE-induced new or aggravated CND completely resolved in almost all cases after embolization with Onyx.

  1. Optical and electrical stimulation of the rat prostate cavernous nerves: priming and fatigue studies

    Science.gov (United States)

    Kaouk, Ghallia S.; Perkins, William C.; Lagoda, Gwen A.; Burnett, Arthur L.; Fried, Nathaniel M.

    2015-02-01

    Optical nerve stimulation (ONS) is being explored as an alternative to electrical nerve stimulation (ENS) for use as an intra-operative diagnostic method for identification and preservation of prostate cavernous nerves (CNs) during radical prostatectomy. Nerve priming and fatigue studies were performed to further characterize CNs and provide insight into the different ONS and ENS mechanisms. ONS studies were conducted using a 1455-nm diode laser, coupled to fiber optic probe, and delivering a collimated, 1-mm-diameter laser spot on CNs. For nerve priming studies, laser power was escalated in 5 mW increments (15 - 60 mW) with each stimulation lasting 15 s, until a strong ICP response was observed, and then power was similarly de-escalated. For ONS fatigue studies, a constant laser power was delivered for a period of 10 min. ENS studies were conducted for comparison, with standard parameters (4 V, 5 ms, 16 Hz) for fatigue studies (10 min. duration), but incrementally increasing/decreasing voltage (0.1 - 4.0 V) for priming studies with 15 s stimulations. ONS threshold was approximately 20% higher during initial escalating laser power steps (6.4 W/cm2) than in subsequently de-escalating laser power steps (5.1 W/cm2), demonstrating a nerve priming effect. Evidence of nerve priming during ENS was not observed. For nerve fatigue studies, ONS of CNs showed a peak ICP response at about 60 s, followed by a gradual decay in ICP, while ENS maintained a strong, but cyclical ICP. Nerve priming may allow repetitive ONS of CNs at lower and hence safer laser power settings. Both nerve priming and fatigue studies revealed different mechanisms for ONS and ENS.

  2. EC-IC bypass for cavernous carotid aneurysms: An initial experience with twelve patients

    Science.gov (United States)

    Menon, G.; Jayanand, Sudhir; Krishnakumar, K.; Nair, S.

    2014-01-01

    Aims: Need for performing a bypass procedure prior to parent artery occlusion in patients with good cerebral vascular reserve is controversial. We analyze our experience of 12 giant internal carotid artery aneurysms treated with extracranial-intracranial (EC-IC) bypass and proximal artery occlusion. Materials and Methods: Retrospective analysis of the case records of all complex carotid aneurysms operated in our institute since January 2009. Results: The study included eleven cavernous carotid aneurysms and one large fusiform cervical carotid aneurysm reaching the skull base. Preoperative assessment of cerebral vascular reserve was limited to Balloon test occlusion with hypotensive challenge. Eleven patients who successfully completed a Balloon test occlusion (BTO) underwent low flow superficial temporal artery to middle cerebral artery (STA-MCA) bypass, while one patient with a failed BTO underwent a high flow bypass using a saphenous vein graft. Parent artery ligation was performed in all patients following the bypass procedure. Check angiogram revealed thrombosis of the aneurysm in all patients with a graft patency rate of 81.8%. We had one operative mortality, probably related to a leak from the anastomotic site. The only patient who had a high flow bypass developed contralateral hemispheric infarcts and remained vegetative. All the other patients had a good recovery and with a Glasgow outcome score of 5 at last follow-up. Conclusion: We feel that combining EC-IC bypass prior to parent vessel occlusion helps in reducing the risk of post operative ischemic complications especially in situations where a complete mandated cerebral blood flow studies are not feasible. PMID:25126123

  3. Morphological Characteristics of the Sphenoid Sinus and Endoscopic Localization of the Cavernous Sinus.

    Science.gov (United States)

    Yang, Youxiong; Zhan, Guowen; Liao, Jianchun; Dang, Ruishan; Wang, Hongli; Li, Yang; Zhang, Xiaote

    2015-09-01

    The aim of this study was to investigate the relationship between the morphological characteristics of the sphenoid sinus and endoscopic localization of the cavernous sinus (CS) using an extended endoscopic endonasal transsphenoidal approach. Thirty sides of CS in 15 adult cadaver heads were dissected to simulate the extended endoscopic endonasal transsphenoidal approach, and the morphology of the sphenoid sinus and anatomic structures of CS were observed. The opticocarotid recess (OCR), ophthalmomaxillary recess (V1V2R), and maxillomandibular recess (V2V3R) in the lateral wall of the sphenoid sinus were presented in 16 sides (53.3%), 6 sides (20%), and 4 sides (13.3%) of the 30 sides, respectively. OCR is a constant anatomic landmark in endoscopy and coincides with the anterior portion of the clinoidal triangle. The C-shaped internal carotid artery (ICA) in the lateral wall of the sphenoid sinus was presented in 11 sides (36.7%), the upper one-third of which corresponds to the middle portion of the clinoidal triangle, and the lower two-thirds of which correlates to the supratrochlear triangle, infratrochlear triangle, and ophthalmic nerve in CS, around which the medial, lateral, and anteroinferior interspaces are distributed. From a front-to-behind perspective, the C-shaped ICA consists of inferior horizontal segment, anterior vertical segment, clinoidal segment as well as partial subarachnoid segment of the ICA. OCR and C-shaped ICA in the lateral wall of the sphenoid sinus are the 2 reliable anatomic landmarks in the intraoperative location of the parasellar region of CS. PMID:26221856

  4. Determination of hydraulic conductivity of fractured rock masses: A case study for a rock cavern project in Singapore

    Directory of Open Access Journals (Sweden)

    Zhipeng Xu

    2015-04-01

    Full Text Available In order to reduce the risk associated with water seepage in an underground rock cavern project in Singapore, a reliable hydro-geological model should be established based on the in situ investigation data. The key challenging issue in the hydro-geological model building is how to integrate limited geological and hydro-geological data to determine the hydraulic conductivity of the fractured rock masses. Based on the data obtained from different stages (feasibility investigation stage, construction stage, and post-construction stage, suitable models and methods are proposed to determine the hydraulic conductivities at different locations and depths, which will be used at other locations in the future.

  5. Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations

    OpenAIRE

    Cunningham, Kirk; Uchida, Yutaka; O'Donnell, Erin; Claudio, Estefania; Li, Wenling; Soneji, Kosha; Wang, Hongshan; Mukouyama, Yoh-suke; Siebenlist, Ulrich

    2011-01-01

    Cerebral cavernous malformations (CCM) are irregularly shaped and enlarged capillaries in the brain that are prone to hemorrhage, resulting in headaches, seizures, strokes and even death in patients. The disease affects up to 0.5% of the population and the inherited form has been linked to mutations in one of three genetic loci, CCM1, CCM2 and CCM3. To understand the pathophysiology underlying the vascular lesions in CCM, it is critical to develop a reproducible mouse genetic model of this di...

  6. Determination of hydraulic conductivity of fractured rock masses:A case study for a rock cavern project in Singapore

    Institute of Scientific and Technical Information of China (English)

    Zhipeng Xu; Zhiye Zhao; Jianping Sun; Ming Lu

    2015-01-01

    In order to reduce the risk associated with water seepage in an underground rock cavern project in Singapore, a reliable hydro-geological model should be established based on the in situ investigation data. The key challenging issue in the hydro-geological model building is how to integrate limited geological and hydro-geological data to determine the hydraulic conductivity of the fractured rock masses. Based on the data obtained from different stages (feasibility investigation stage, construction stage, and post-construction stage), suitable models and methods are proposed to determine the hy-draulic conductivities at different locations and depths, which will be used at other locations in the future.

  7. Incidental direct carotid-cavernous fistula in a patient with high-grade internal carotid artery stenosis

    International Nuclear Information System (INIS)

    The concurrent occurrence of internal carotid artery (ICA) stenosis and carotid-cavernous fistula (CCF) is infrequent. We report the case of a 59-year-old man with symptomatic high-grade stenosis of left ICA who was referred to our hospital for surgical treatment. An ipsilateral direct CCF was found incidentally during operation. Ultimately, the two lesions were successfully treated with a covered stent while the ICA was preserved. The result of our study may provide further insight into this rare combination of diseases. (author)

  8. Ehlers-Danlos syndrome type IV and recurrent carotid-cavernous fistula: review of the literature, endovascular approach, technique and difficulties

    Energy Technology Data Exchange (ETDEWEB)

    Desal, H.A.; Toulgoat, F.; Raoul, S.; Guillon, B.; Bommard, S.; Naudou-Giron, E.; Auffary-Calvier, E.; Kersaint-Gilly, A. de [Department of Neuroradiology, Laennec Hospital, University of Nantes (France); 1

    2005-04-01

    We report the follow-up of a previously published case (Forlodou et al. Neuroradiology 38:595-597, 1996) of carotido-cavernous fistulas (CCFs) in a patient presenting with type IV Ehlers-Danlos syndrome (EDS 4) that were successfully treated twice by an endovascular approach. Initial treatment with a detachable balloon was in 1994 for a right CCF, and, 8 years later, a left CCF was treated by selective transarterial occlusion of the cavernous sinus with coils. Unfortunately, the patient suffered from a spontaneous post-operative intracranial haemorrhage in the left hemisphere and died. Review of the literature, technical considerations for bilateral CCF and complication are discussed.

  9. Structural Stability Monitoring of a Physical Model Test on an Underground Cavern Group during Deep Excavations Using FBG Sensors

    Science.gov (United States)

    Li, Yong; Wang, Hanpeng; Zhu, Weishen; Li, Shucai; Liu, Jian

    2015-01-01

    Fiber Bragg Grating (FBG) sensors are comprehensively recognized as a structural stability monitoring device for all kinds of geo-materials by either embedding into or bonding onto the structural entities. The physical model in geotechnical engineering, which could accurately simulate the construction processes and the effects on the stability of underground caverns on the basis of satisfying the similarity principles, is an actual physical entity. Using a physical model test of underground caverns in Shuangjiangkou Hydropower Station, FBG sensors were used to determine how to model the small displacements of some key monitoring points in the large-scale physical model during excavation. In the process of building the test specimen, it is most successful to embed FBG sensors in the physical model through making an opening and adding some quick-set silicon. The experimental results show that the FBG sensor has higher measuring accuracy than other conventional sensors like electrical resistance strain gages and extensometers. The experimental results are also in good agreement with the numerical simulation results. In conclusion, FBG sensors could effectively measure small displacements of monitoring points in the whole process of the physical model test. The experimental results reveal the deformation and failure characteristics of the surrounding rock mass and make some guidance for the in situ engineering construction. PMID:26404287

  10. Structural Stability Monitoring of a Physical Model Test on an Underground Cavern Group during Deep Excavations Using FBG Sensors

    Directory of Open Access Journals (Sweden)

    Yong Li

    2015-08-01

    Full Text Available Fiber Bragg Grating (FBG sensors are comprehensively recognized as a structural stability monitoring device for all kinds of geo-materials by either embedding into or bonding onto the structural entities. The physical model in geotechnical engineering, which could accurately simulate the construction processes and the effects on the stability of underground caverns on the basis of satisfying the similarity principles, is an actual physical entity. Using a physical model test of underground caverns in Shuangjiangkou Hydropower Station, FBG sensors were used to determine how to model the small displacements of some key monitoring points in the large-scale physical model during excavation. In the process of building the test specimen, it is most successful to embed FBG sensors in the physical model through making an opening and adding some quick-set silicon. The experimental results show that the FBG sensor has higher measuring accuracy than other conventional sensors like electrical resistance strain gages and extensometers. The experimental results are also in good agreement with the numerical simulation results. In conclusion, FBG sensors could effectively measure small displacements of monitoring points in the whole process of the physical model test. The experimental results reveal the deformation and failure characteristics of the surrounding rock mass and make some guidance for the in situ engineering construction.

  11. Effect of installing monobars in stability of powerhouse cavern roof in Masjed-Soleiman power plant extension

    Energy Technology Data Exchange (ETDEWEB)

    Shahabi, M. [Moshanir, Tehran (Iran, Islamic Republic of); Shahverdiloo, M.R. [Moshanir, Masjed-Soleiman (Iran, Islamic Republic of)

    2003-07-01

    The Masjed-e-Soleiman Dam and Hydroelectric Power Plant consists of a 170 metres high rock fill dam with a capacity of 2000 mega watts (MW). This power plant is located approximately 25 kilometres northeast of Masjed-e-Soleiman on the Karun River in southwestern Iran. The underground cavern houses the powerhouse, which consists of eight 250 MW power units (4 units for phase 1 and 4 units for the extension phase). The overburden of the powerhouse is 250-320 metres. The recent completion of the first step of the project involved a dam which supplies 1000 MW of electricity. This paper describes the installation of monobars to ensure the stability of the roof of the extension. It also provides a brief overview of the geological condition, rock support measures and the sequences of excavation for the extension powerhouse cavern. The impact that the installation of the monobars had on roof stability, based on instrumentation results, was examined. 4 refs., 1 tab., 9 figs.

  12. Dynamic subsidence prediction of ground surface above salt cavern gas storage considering the creep of rock salt

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    A new model is proposed to predict the dynamic subsidence of ground surface above salt cavern gas storage during the leaching and storage, which takes into account the creep of rock salt. In the model, the extended form of Gaussian curve is adopted to figure out the shape of subsidence areas. The corresponding theoretical formulas are derived. In addition, parameters are studied to investigate the surface subsidence as a function of the salt ejection rate, internal pressure, buried depth, diameter, height, running time, etc. Through an example, the subsidence of the salt cavern gas storage located at Jiangsu of China obtained by the new model was compared with those by Peter A F formula, Schober & Sroka formula and FLAC3D through simulation. The results showed the proposed model is precise and correct, and can meet the actual engineering demands. The surface subsidence is equidirectional with the increase of salt ejection rate, depth, diameter, height, and running time, but reverse to the increase of internal pressure. The depth, diameter, running time and internal pressure have great effects on the subsidence, whereas the salt ejection rate and height have little influences on it.

  13. Depiction of the cranial nerves around the cavernous sinus by 3D reversed FISP with diffusion weighted imaging (3D PSIF-DWI)

    International Nuclear Information System (INIS)

    The purpose of this study was to evaluate the anatomy of cranial nerves running in and around the cavernous sinus, we employed three-dimensional reversed fast imaging with steady-state precession (FISP) with diffusion weighted imaging (3D PSIF-DWI) on 3-T magnetic resonance (MR) system. After determining the proper parameters to obtain sufficient resolution of 3D PSIF-DWI, we collected imaging data of 20-side cavernous regions in 10 normal subjects. 3D PSIF-DWI provided high contrast between the cranial nerves and other soft tissues, fluid, and blood in all subjects. We also created volume-rendered images of 3D PSIF-DWI and anatomically evaluated the reliability of visualizing optic, oculomotor, trochlear, trigeminal, and abducens nerves on 3D PSIF-DWI. All 20 sets of cranial nerves were visualized and 12 trochlear nerves and 6 abducens nerves were partially identified. We also presented preliminary clinical experiences in two cases with pituitary adenomas. The anatomical relationship between the tumor and cranial nerves running in and around the cavernous sinus could be three-dimensionally comprehended by 3D PSIF-DWI and the volume-rendered images. In conclusion, 3D PSIF-DWI has great potential to provide high resolution 'cranial nerve imaging', which visualizes the whole length of the cranial nerves including the parts in the blood flow as in the cavernous sinus region. (author)

  14. A rare variant of persistent trigeminal artery: cavernous carotid-cerebellar artery anastomosis--a case report and a systematic review.

    Science.gov (United States)

    Raphaeli, Guy; Bandeira, Alexandra; Mine, Benjamin; Brisbois, Denis; Lubicz, Boris

    2009-12-01

    We report a very rare anomalous anatomic variant of the cavernous internal carotid artery supplying directly the posterior inferior cerebellar artery, with no basilar artery opacification. A systematic review as well as a description of other variants of trigeminal-cerebellar anastomosis is given. PMID:19517204

  15. Ruptured hepatic cavernous hemangioma: a case report and literature review; Hemangioma cavernoso hepatico roto: relato de caso e revisao da literatura

    Energy Technology Data Exchange (ETDEWEB)

    Paula Neto, Walter Teixeira de [Hospital Uniclinicas, Chapeco, SC (Brazil). Servico de Radiologia e Diagnostico por Imagem], e-mail: walterteixeira21@yahoo.com.br; Koifman, Ana Celia Baptista [Hospital Municipal Souza Aguiar, Rio de Janeiro, RJ (Brazil); Martins, Carlos Alberto de Souza [Sociedade Brasileira de Radiologia (SBR), Rio de Janeiro, RJ (Brazil); Clinica Life Imagem, Rio de Janeiro, RJ (Brazil)

    2009-07-15

    Hepatic hemangioma is frequently asymptomatic, and bleeding is rare, even in cases of large lesions. The authors report the case of a 31-year-old female patient presenting with acute abdominal pain, whose imaging studies have demonstrated hematoma in the left hepatic lobe associated with hemo peritoneum. The patient was submitted to left hepatectomy, with a final histopathological diagnosis of cavernous hemangioma. (author)

  16. Neuromedin B Restores Erectile Function by Protecting the Cavernous Body and the Nitrergic Nerves from Injury in a Diabetic Rat Model.

    Directory of Open Access Journals (Sweden)

    Hiroaki Nishimatsu

    Full Text Available Erectile dysfunction (ED is a major health problem worldwide and affects approximately 75% of diabetic patients, likely due to severely damaged cavernous body. While screening for cytokines produced by adipose tissue-derived stem cells, we detected neuromedin B (NMB. To explore a potential treatment option for ED, we examined whether NMB was capable of restoring erectile function. We also examined the potential mechanism by which NMB could restore erectile function. Male Wistar rats were injected with streptozotocin (STZ to induce diabetes. An adenovirus expressing NMB (AdNMB was injected into the penis 6 weeks after STZ administration. Four weeks after the injection of AdNMB, erectile function, penile histology, and protein expression were analyzed. As assessed by the measurement of intracavernous pressure, AdNMB injection significantly restored erectile function compared with the injection of an adenovirus expressing green fluorescent protein. This restoration was associated with conservation of the cavernous body structure and neural nitric oxide synthase (nNOS-expressing nerves, together with recovery of α-smooth muscle actin, vascular endothelial-cadherin, and nNOS expression. Furthermore, NMB significantly stimulated the survival of SH-SY5Y cells derived from human neuroblastoma tissue with characteristics similar to neurons. Collectively, these results suggested that NMB restored erectile function via protection of the cavernous body from injury and stimulation of the survival of the associated nerves. NMB may be useful to treat ED patients with a severely damaged cavernous body.

  17. Neuromedin B Restores Erectile Function by Protecting the Cavernous Body and the Nitrergic Nerves from Injury in a Diabetic Rat Model.

    Science.gov (United States)

    Nishimatsu, Hiroaki; Suzuki, Etsu; Saito, Yasuho; Niimi, Aya; Nomiya, Akira; Yamada, Daisuke; Homma, Yukio

    2015-01-01

    Erectile dysfunction (ED) is a major health problem worldwide and affects approximately 75% of diabetic patients, likely due to severely damaged cavernous body. While screening for cytokines produced by adipose tissue-derived stem cells, we detected neuromedin B (NMB). To explore a potential treatment option for ED, we examined whether NMB was capable of restoring erectile function. We also examined the potential mechanism by which NMB could restore erectile function. Male Wistar rats were injected with streptozotocin (STZ) to induce diabetes. An adenovirus expressing NMB (AdNMB) was injected into the penis 6 weeks after STZ administration. Four weeks after the injection of AdNMB, erectile function, penile histology, and protein expression were analyzed. As assessed by the measurement of intracavernous pressure, AdNMB injection significantly restored erectile function compared with the injection of an adenovirus expressing green fluorescent protein. This restoration was associated with conservation of the cavernous body structure and neural nitric oxide synthase (nNOS)-expressing nerves, together with recovery of α-smooth muscle actin, vascular endothelial-cadherin, and nNOS expression. Furthermore, NMB significantly stimulated the survival of SH-SY5Y cells derived from human neuroblastoma tissue with characteristics similar to neurons. Collectively, these results suggested that NMB restored erectile function via protection of the cavernous body from injury and stimulation of the survival of the associated nerves. NMB may be useful to treat ED patients with a severely damaged cavernous body. PMID:26207818

  18. The ATLAS installation team, led by Tommi Nyman, after having positioned the Barrel Calorimeter in its final location in the ATLAS experimental cavern UX15

    CERN Document Server

    2005-01-01

    On Friday 4th November, the ATLAS Barrel Calorimeter was moved from its assembly point at the side of the ATLAS cavern to the centre of the toroidal magnet system. The detector was finally aligned, to the precision of within a millimetre, on Wednesday 9th November.

  19. Direct Carotid Cavernous Fistula of an Adult-Type Persistent Primitive Trigeminal Artery with Multiple Vascular Variations

    Science.gov (United States)

    Jin, Sung-Chul; Park, Hyun; Choi, Choong-Gon

    2011-01-01

    We report a case of spontaneous right carotid-cavernous fistula (CCF) in a proximal segment of persistent primitive trigeminal artery (PPTA) and combined vascular anomalies such as left duplicated hypoplastic proximal posterior cerebral arteries and a variation of anterior choroidal artery supplying temporal and occipital lobe. A 45-year-old male presented with progressive right exophthalmos, diplopia, and ocular pain. With manual compression of the internal carotid artery, a cerebral angiography revealed a right CCF from a PPTA. Treatment involved the placement of detachable non-fibered and fibered coils, and use of a hyperglide balloon to protect against coil herniation into the internal carotid artery. A final angiograph revealed complete occlusion of PPTA resulted in no contrast filling of CCF. PMID:21607181

  20. Direct carotid cavernous fistula of an adult-type persistent primitive trigeminal artery with multiple vascular variations.

    Science.gov (United States)

    Jin, Sung-Chul; Park, Hyun; Kwon, Do Hoon; Choi, Choong-Gon

    2011-04-01

    We report a case of spontaneous right carotid-cavernous fistula (CCF) in a proximal segment of persistent primitive trigeminal artery (PPTA) and combined vascular anomalies such as left duplicated hypoplastic proximal posterior cerebral arteries and a variation of anterior choroidal artery supplying temporal and occipital lobe. A 45-year-old male presented with progressive right exophthalmos, diplopia, and ocular pain. With manual compression of the internal carotid artery, a cerebral angiography revealed a right CCF from a PPTA. Treatment involved the placement of detachable non-fibered and fibered coils, and use of a hyperglide balloon to protect against coil herniation into the internal carotid artery. A final angiograph revealed complete occlusion of PPTA resulted in no contrast filling of CCF. PMID:21607181

  1. Progression of unilateral moyamoya disease resulted in spontaneous occlusion of ipsilateral cavernous dural arteriovenous fistula: Case report.

    Science.gov (United States)

    Liu, Peng; Xu, Ya; Lv, Xianli; Ge, Huijian; Lv, Ming; Li, Youxiang

    2016-06-01

    The pathogenic association between cavernous dural arteriovenous fistula (CDAVF) and moyamoya disease remains unclear. This unusual case is the first report of a progression of unilateral moyamoya disease resulting in the spontaneous occlusion of ipsilateral CDAVF. A 52-year-old woman presented with two-week spontaneous exophthalmos, chemosis and tinnitus, and cerebral angiography showed a right CDAVF coexisting with ipsilateral moyamoya disease. Transvenous approaches through the inferior petrosal sinus and facial vein were attempted but failed. However, a progression of the moyamoya disease and disappearance of the CDAVF were observed on one month follow-up angiogram in accordance with the resolution of clinical symptoms. This extremely rare coincidental presentation may have deeper pathogenic implications. This case report may give a clue to the underlying mechanism of the progression of moyamoya disease and occlusion of the CDAVF. PMID:26916656

  2. Support behaviour of a salt cavern in great depth under atmospheric pressure; Tragverhalten tiefliegender Salzkavernen bei atmosphaerischem Innendruck

    Energy Technology Data Exchange (ETDEWEB)

    Hauck, R.

    2001-07-01

    In the paper the IUB method for the proof of stability of a salt cavern in great depth under atmospheric pressure was compared to a method on the basis of the continuum damage mechanic theory with regard to the necessary application of engineering experience in the assessment of the results. The central part of the proof of stability for the case of a cavern blow out is the assessment of the spalling process with time. Based on the combination of the results of numerical calculations and laboratory tests with the method IUB it becomes possible to asses the development of fracture zones in the rock mass with time. For the calculation example of a cavern under atmospheric pressure a fracture zone of 14 m in 200 days was predicted. With the application of material laws on the basis of the continuum damage theory, as f.e. the MDCF model, it is possible to simulate the process of damage which leads to spalling. With regard to the question to be investigated the definition of the dilatancy boundary and the evolutionary function of damage had to be modified. For the creep rupture criterion a maximum value of the damage variable {omega} was chosen. Its value was defined assessing creep rupture times of laboratory tests with perforated test samples. In the assessment of the spalling process it has to be considered that the damage variable can only describe the softening of a load bearing area but not its total loss. Taking this into account a fracture zone of 9 to 12 m was predicted for the calculation example. It could be concluded that in the assessment of the process of spalling with time in case of a cavern blow out the application of engineering experience on the results of the numerical analysis and laboratory tests is still necessary using a material law based on the continuum damage mechanics theory. (orig.) [German] In der vorliegenden Arbeit wurde das Verfahren IUB fuer den Nachweis der Standsicherheit einer tiefliegenden Salzkaverne unter atmosphaerischem

  3. Lead shielding efficiency from the gamma background measurements in the salt cavern of the Polkowice-Sieroszowice copper mine

    International Nuclear Information System (INIS)

    The studies of lead shielding efficiency from the gamma background measurements were performed in the salt cavern of the copper mine - a site considered for an underground laboratory. Within the energy range of 50-2700 keV, the measured gamma-ray count rates normalized to the mass of the high-purity detectors germanium crystal are 5.93 and 6.32 s-1kg-1 for the used low-background and portable spectrometers, respectively. The gamma-ray flux of 0.124 (2) cm-2 s-1 connected with the natural radioisotopes was observed by the portable HPGe, including 0.026 (1) cm-2 s-1 contribution of radon decay products, whereas the photon flux at the spectrum continuum was 0.18 (5) cm-2 s-1. (author)

  4. On the use of hydrate inhibitors for operating natural gas caverns; Zum Einsatz von Hydratinhibitoren beim Betrieb von Erdgasspeichern

    Energy Technology Data Exchange (ETDEWEB)

    Kleinitz, W.; Lissanon, S.J.; Luehn, H.G. [Preussag Energie GmbH, Lingen/Ems (Germany)

    1997-12-31

    One way to prevent gas hydrates in natural gas caverns is to use thermodynamic or kinetic inhibitors in a defined temperature / pressure range. The present contribution describes the temperature conditions prevailing in the tubing string. It also discusses bacterial processes around wells arising in association with methanol digesting bacteria, diethylene glycol digesting bacteria, and kinetic inhibitors. Further topics include inhibitor dosage and absorption drying. (MSK) [Deutsch] Zur Vermeidung von Gashydraten im Erdgasspeicherbereich werden thermodynamische oder kinetische Inhibitoren in einem definierten Temperatur/Druckbereich eingesetzt. Im Folgenden werden die Temperaturbedingungen im Steigrohrsystem erlaeutert. Ebenso werden die bakteriellen Vorgaenge im Bohrlochsbereich in folgenden Einzelheiten: Methanol-verwertenden Bakterien, Diethylenglykol-verwertende Bakterien sowie kinetische Inhibitoren diskutiert. Weitere Themenpunkte sind die Inhibitordosierung und die Adsorptionstrocknung.

  5. Endoscope-assisted supracerebellar transtentorial approach to the posterior medial temporal lobe for resection of cavernous malformation.

    Science.gov (United States)

    Kalani, M Yashar S; Lei, Ting; Martirosyan, Nikolay L; Oppenlander, Mark E; Spetzler, Robert F; Nakaji, Peter

    2016-01-01

    The mesial temporal lobe can be approached via a pterional or orbitozygomatic craniotomy, the subtemporal approach, or transcortically. Alternatively, the entire mesial temporal lobe can be accessed using a lateral supracerebellar transtentorial (SCTT) approach. Here we describe the technical nuances of patient positioning, craniotomy, supracerebellar dissection, and tentorial disconnection to traverse the tentorial incisura to arrive at the posterior mesial temporal lobe for a cavernous malformation. The SCTT approach is especially useful for lesions in the dominant temporal lobe where an anterolateral approach may endanger language centers or the vein of Labbé. The video can be found here: https://youtu.be/D8mIR5yeiVw . PMID:26722685

  6. 21 October 2008 - LHC Inauguration - Deputy Minister for Environment, Physical Planning and Public Works T. Xanthopulos welcomed by CERN Director-General R. Aymar, visiting the ATLAS cavern and LHC tunnel and signing the electronic guest book with E. Tsesmelis.

    CERN Multimedia

    CERN Photo Service

    2008-01-01

    21 October 2008 - LHC Inauguration - Deputy Minister for Environment, Physical Planning and Public Works T. Xanthopulos welcomed by CERN Director-General R. Aymar, visiting the ATLAS cavern and LHC tunnel and signing the electronic guest book with E. Tsesmelis.

  7. 09 September 2013 - Japanese Members of Internal Affairs and Communications Committee House of Representatives visiting the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton. T. Kondo and K. Yoshida present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    09 September 2013 - Japanese Members of Internal Affairs and Communications Committee House of Representatives visiting the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton. T. Kondo and K. Yoshida present.

  8. 19 September 2012 - Indonesian Members of Parliament visiting the CMS control room and experimental cavern at Point 5 with Former Deputy Spokesperson A. De Roeck and International Relations Adviser E. Tsesmelis.

    CERN Multimedia

    Jean-Claude Gadmer

    2012-01-01

    19 September 2012 - Indonesian Members of Parliament visiting the CMS control room and experimental cavern at Point 5 with Former Deputy Spokesperson A. De Roeck and International Relations Adviser E. Tsesmelis.

  9. 12 April 2013 - The British Royal Academy of Engineering visiting the LHC superconducting magnet test hall with R. Veness and the ATLAS experimental cavern with Collaboration Spokesperson D. Charlton.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    12 April 2013 - The British Royal Academy of Engineering visiting the LHC superconducting magnet test hall with R. Veness and the ATLAS experimental cavern with Collaboration Spokesperson D. Charlton.

  10. 18 MArch 2008 - Director, Basic and Generic Research Division, Research Promotion Bureau, Japanese Ministry of Education, Culture, Sports, Science and Technology Prof.Ohtake visiting ATLAS cavern with Spokesperson P. Jenni.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    18 MArch 2008 - Director, Basic and Generic Research Division, Research Promotion Bureau, Japanese Ministry of Education, Culture, Sports, Science and Technology Prof.Ohtake visiting ATLAS cavern with Spokesperson P. Jenni.

  11. Dr Mauro Dell’Ambrogio, State Secretary for Education and Research of the Swiss Confederation visit the ATLAS Cavern and the LHC Machine with with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    Dr Mauro Dell’Ambrogio, State Secretary for Education and Research of the Swiss Confederation visit the ATLAS Cavern and the LHC Machine with with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

  12. 17 September 2013 - Polish Members of Parliament visiting the Tunnel at Point 2 with Senior Engineer, Technology Department A. Siemko and visiting the ALICE cavern with ALICE Collaboration, B. Erazmus

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    17 September 2013 - Polish Members of Parliament visiting the Tunnel at Point 2 with Senior Engineer, Technology Department A. Siemko and visiting the ALICE cavern with ALICE Collaboration, B. Erazmus

  13. 29 May 2013 - Rector Politecnico di Torino M. Gilli in the ATLAS experimental cavern with L. Pontecorvo (ATLAS Collaboration) and in the LHC tunnel at Point 1 with Engineering Department Head R. Saban.

    CERN Multimedia

    VMO

    2013-01-01

    29 May 2013 - Rector Politecnico di Torino M. Gilli in the ATLAS experimental cavern with L. Pontecorvo (ATLAS Collaboration) and in the LHC tunnel at Point 1 with Engineering Department Head R. Saban.

  14. March 2008 - ITER Organization Director-General K.Ikeda and Deputy Director-General N. Holtkamp, visiting the ATLAS cavern with Spokesperson P. Jenni, Accelerators Technology Department Head P. Lebrun and LHC Mangnets Group Leader L. Rossi.

    CERN Multimedia

    Claudia Marcelloni

    2008-01-01

    March 2008 - ITER Organization Director-General K.Ikeda and Deputy Director-General N. Holtkamp, visiting the ATLAS cavern with Spokesperson P. Jenni, Accelerators Technology Department Head P. Lebrun and LHC Mangnets Group Leader L. Rossi.

  15. 10 September 2013 - Italian Minister for Economic Development F. Zanonato visiting the ATLAS cavern with Collaboration Spokesperson D. Charlton and Italian scientists F. Gianotti and A. Di Ciaccio; signing the guest book with CERN Director-General R. Heuer and Director for Research and Scientific Computing S. Bertolucci; in the LHC tunnel with S. Bertolucci, Technology Deputy Department Head L. Rossi and Engineering Department Head R. Saban; visiting CMS cavern with Scientists G. Rolandi and P. Checchia.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    10 September 2013 - Italian Minister for Economic Development F. Zanonato visiting the ATLAS cavern with Collaboration Spokesperson D. Charlton and Italian scientists F. Gianotti and A. Di Ciaccio; signing the guest book with CERN Director-General R. Heuer and Director for Research and Scientific Computing S. Bertolucci; in the LHC tunnel with S. Bertolucci, Technology Deputy Department Head L. Rossi and Engineering Department Head R. Saban; visiting CMS cavern with Scientists G. Rolandi and P. Checchia.

  16. Familial cerebral cavernous malformations: Rio de Janeiro study and review of the recommendations for management Malformação cavernosa cerebral familiar: um estudo no Rio de Janeiro e revisão das recomendações para tratamento

    OpenAIRE

    Flávio Domingues; Gasparetto, Emerson L.; Ricardo Andrade; Fabio Noro; Antônio Eiras; Judith Gault; Carlos Eduardo Silva Correia; Jorge Marcondes de Souza

    2008-01-01

    OBJECTIVE: Multiple cerebral cavernous malformation (CCM) is the hallmark of familial presentation of cavernous malformation in the brain. We describe an ongoing Familial Cerebral Cavernous Malformation Project in the Rio de Janeiro state showing genetic profile and the pattern of emergent neuroimaging findings of this particular population besides a review of the updated recommendations for management of familial CCM versus patients harboring sporadic lesions. METHOD: Four families of our co...

  17. 海绵体神经损伤所致ED大鼠模型建立%Rat model of erectile dysfunction caused by cavernous nerve ablation

    Institute of Scientific and Technical Information of China (English)

    张新华; 胡礼泉; 尹静; 莫曾南; 陈坚

    2002-01-01

    目的寻找大鼠海绵体神经并建立神经损伤所致ED大鼠模型.方法对20只大鼠进行解剖,在外科显微镜下找到海绵体神经并经电刺激试验证实.随后将42只实验大鼠随机分为假手术对照组、单侧海绵体神经损伤组及双侧海绵体神经损伤组.术后3周用阿朴吗啡试验来评估所建动物模型.结果盆主要神经节位于背侧前列腺后外侧叶表面,其最大的传出神经就是海绵体神经.诱发阴茎勃起的电刺激参数是:电压5V、刺激频率20Hz及刺激时间5ms.术后3周,阿朴吗啡均能诱发对照组大鼠阴茎勃起,30分钟内平均勃起次数为2.57±1.40,实验组大鼠,无论单侧损伤还是双侧损伤,均丧失勃起功能(0.00±0.00).结论大鼠较大的盆主要神经节及海绵体神经易于辨认,电刺激反应明显,而且大鼠价格便宜,易于饲养及购买,是建立海绵体神经损伤性ED模型的理想动物.此外还发现,无论是单侧海绵体神经损伤还是双侧损伤,损伤后早期,大鼠均丧失勃起功能.%Objective To identify the rat cavernous nerve and establish a rat model of erectile dysfunction (ED) caused by injury of the cavernous nerve. Methods Twenty rats underwent dissections. Cavernous nerves were identified with the aid of an operating microscope and confirmed by electrical stimulation. Then, 42 experimental rats were randomized into 3 groups, including sham-operated controls and unilateral and bilateral cavernous nerve ablation groups. Three weeks after surgery, rat models were evaluated with the Apomorphine test.Results The major pelvic ganglion lies on either side of the dorsolateral lobes of the prostate. It includes 2 inflows, one called hypogastric nerve and the other, the pelvic nerve. The largest outflow is termed the cavernous nerve. Stimulus parameters which could induce obvious penile erection were 5 volts, a frequency of 20 Hertz and a duration of 5 milliseconds. Three weeks after surgery, apomorphine

  18. Endovascular treatment of a cavernous sinus dural arteriovenous fistula by transvenous embolisation through the superior ophthalmic vein via cannulation of a frontal vein

    Energy Technology Data Exchange (ETDEWEB)

    Venturi, C.; Bracco, S.; Cerase, A.; Gennari, P. [Unit of Diagnostic and Therapeutic Neuroradiology, Policlinico ' ' Le Scotte' ' , Azienda Ospedaliera Universitaria Senese, Viale Mario Bracci 16, 53100, Siena (Italy); Lore, F. [Institute of Endocrinology, Policlinico ' ' Le Scotte' ' , University of Siena, Viale Mario Bracci 16, 53100, Siena (Italy); Polito, E. [Institute of Ophthalmology, Policlinico ' ' Le Scotte' ' , University of Siena, Viale Mario Bracci 16, 53100, Siena (Italy); Casasco, A.E. [Department of Endovascular and Percutaneous Therapy, Clinica Nuestra Senora del Rosario, Madrid (Spain)

    2003-08-01

    We describe a new approach for transvenous embolisation of cavernous sinus dural arteriovenous fistulae through the superior ophthalmic vein (SOV), i.e., via percutaneous cannulation of a frontal vein. Modern neurointerventional angiographic materials make it possible to reach the SOV in this way without puncturing it in the orbit or a surgical exposure. Orbital phlebography should still be in the repertoire of interventional neuroradiology units in large centres. (orig.)

  19. Paradoxical Exacerbation of Symptoms with Obstruction of the Venous Outflow after Gamma Knife Radiosurgery for Treatment of a Dural Arteriovenous Fistula of the Cavernous Sinus

    OpenAIRE

    Ko, Jun Kyeung; CHO, WON HO; Lee, Tae Hong; Choi, Chang Hwa

    2015-01-01

    A 59-year-old female presented with progressive right proptosis, chemosis and ocular pain. An imaging work-up including conventional catheter angiography showed a right-sided dural arteriovenous fistula of the cavernous sinus, which drained into the right superior petrosal sinus, right superior ophthalmic vein, and right inferior ophthalmic vein, and cortical venous reflux was seen via the right petrosal vein in the right posterior fossa. After failure of transvenous embolization, the patient...

  20. Control Effect of a Large Geological Discontinuity on the Seismic Response and Stability of Underground Rock Caverns: A Case Study of the Baihetan #1 Surge Chamber

    Science.gov (United States)

    Cui, Zhen; Sheng, Qian; Leng, Xianlun

    2016-06-01

    In this paper, the seismic stability of the #1 surge chamber of the Baihetan hydropower plant, which is influenced by a large dominating geological discontinuity [the interlayer shear weakness zone (ISWZ) C2)], is studied. An advanced, nonlinear, continuously yielding (CY) model was adopted to describe the complex mechanical properties of ISWZ C2. This model considers a power function type, normal stress dependent behavior and the progressive damage that occurred during shear tests. The applicability of the CY model is proved via a comparison with field test results and the theoretical solution. Verification work was conducted in 3DEC code to show that the 3DEC software is suitable for implementing this model. Three ground motion waveforms were utilized to conduct a seismic analysis of the #1 surge chamber after a special response spectrum matching process. The seismic analysis confirmed the control effect of ISWZ C2 on the seismic stability of the cavern. The majority of the cavern's seismic displacement consists of elastic body movement, while the plastic deformation is relatively limited. Further, most of the deformations were caused by the contact deformation of C2. For the contact deformation of C2, the magnitude of permanent shear deformation is larger than that of the normal deformation. The magnitude of permanent shear deformation is more notable along the strike direction of C2, and the permanent normal displacement n of C2 mainly occurs along the dip direction of C2. Finally, the seismic stability of the cavern is assessed via the overload method. The seismic safety factor of the cavern is approximately 2-3.

  1. Endovascular treatment of a cavernous sinus dural arteriovenous fistula by transvenous embolisation through the superior ophthalmic vein via cannulation of a frontal vein

    International Nuclear Information System (INIS)

    We describe a new approach for transvenous embolisation of cavernous sinus dural arteriovenous fistulae through the superior ophthalmic vein (SOV), i.e., via percutaneous cannulation of a frontal vein. Modern neurointerventional angiographic materials make it possible to reach the SOV in this way without puncturing it in the orbit or a surgical exposure. Orbital phlebography should still be in the repertoire of interventional neuroradiology units in large centres. (orig.)

  2. Identification of mechanisms involved in the relaxation of rabbit cavernous smooth muscle by a new nitric oxide donor ruthenium compound

    Directory of Open Access Journals (Sweden)

    João Batista Gadelha de Cerqueira

    2012-10-01

    Full Text Available PURPOSE: The aim of this study was to evaluate the relaxation in vitro of cavernous smooth muscle induced by a new NO donor of the complex nitrosil-ruthenium, named trans-[Ru(NH34(caffeine(NO]C13 (Rut-Caf and sodium nitroprusside (SNP. MATERIALS AND METHODS: The tissues, immersed in isolated bath systems, were pre-contracted with phenilephrine (PE (1 µM and then concentration-response curves (10-12 - 10-4 M were obtained. To clarify the mechanism of action involved, it was added to the baths ODQ (10 µM, 30 µM, oxyhemoglobin (10 µM, L-cysteine (100 µM, hydroxicobalamine (100 µM, glibenclamide, iberotoxin and apamine. Tissue samples were frozen in liquid nitrogen to measure the amount of cGMP and cAMP produced. RESULTS: The substances provoked significant relaxation of the cavernous smooth muscle. Both Rut-Caf and SNP determined dose-dependent relaxation with similar potency (pEC50 and maximum effect (Emax. The substances showed activity through activation of the soluble guanylyl cyclase (sGC, because the relaxations were inhibited by ODQ. Oxyhemoglobin significantly diminished the relaxation effect of the substances. L-cysteine failed to modify the relaxations caused by the agents. Hydroxicobalamine significantly diminished the relaxation effect of Rut-Caf. Glibenclamide significantly increased the efficacy of Rut-Caf (pEC50 4.09 x 7.09. There were no alterations of potency or maximum effect of the substances with the addition of the other ion channel blockers. Rut-Caf induced production of significant amounts of cGMP and cAMP during the relaxation process. CONCLUSIONS: In conclusion, Rut-Caf causes relaxation of smooth muscle of corpus cavernosum by means of activation of sGC with intracellular production of cGMP and cAMP; and also by release of NO in the intracellular environment. Rut-Caf releases the NO free radical and it does not act directly on the potassium ion channels.

  3. New peculiar cave ceiling forms from Carlsbad Caverns (New Mexico, USA): The zenithal ceiling tube-holes

    Science.gov (United States)

    Calaforra, Jose-Maria; De Waele, Jo

    2011-11-01

    During a trip to the Hall of the White Giant, Carlsbad Caverns (NM, USA) cigar-shaped vertically upward developing holes were observed on the ceiling at different heights of the passages. They have a circular cross-section with diameters of 1 to some centimetres and taper out towards their upper end. Their walls are smooth and their bottom edges are sharp, while their length can reach several decimetres. Sometimes gypsum can be found inside. They often occur randomly distributed in groups and their development is not necessarily controlled by fractures or other bedrock structures. We name these peculiar karren-like cave microforms “zenithal ceiling tube-holes” because of their origin by H2S environment corrosion processes and their vertical (zenithal) upward growth in ceilings. A comparison is made between zenithal ceiling tube-holes and other karstic or non karstic similar forms such as bell holes, oxidation vents, snailholes, Korrosionskolke (mixture-solution hollows) or pockets, röhrenkarren, light-oriented photokarren, borings of (often marine) organisms and negative stalactites. Zenithal ceiling tube-holes are created by the corrosive effect of sulphuric acid. H2S(g) dissolves in water giving rise to widespread sulphuric acid corrosion. When H2S bubbles are trapped underneath overhanging surfaces or ceilings and water level rises steadily the corrosive effect is concentrated vertically upwards, drilling vertical holes that can also completely pass overhanging rock ledges.

  4. A true 3D physical model test study on the stability of an underground cavern group in Shuangjiangkou Hydropower Station

    Science.gov (United States)

    Zhu, Weishen; Zhang, Lei; Li, Yong; Zhang, Qianbing

    2010-03-01

    Taking the underground caverns of Shuangjiangkou (SJK) Hydropower Station as an engineering background, a largescale true 3D physical model test is performed to study the stability of the enclosing rock masses, including the analogous material, the steel structure frame, fabrications of rock bolts and cables, development of the measuring techniques, fabrication of the physical model, excavations and the overload test. The developed steel structure can simulate the complicated circumstances just like high in-situ stress and high overburden depth. It also can apply the true 3D loading on six surfaces of the physical model. Many combinational ball sliding blocks are installed between model surface and the structural wall to reduce the friction between the contact surfaces. During the model construction, precast blocks are used and monitoring holes are predefined before the analogous material is piled up. A unique grouting technique and prestressed cables are adopted in the model test. A digital photogrammetric technique, displacement sensing bars based on Fiber Bragg Gratings (FBG) technology, and mini extensometers are developed and adopted for measuring the deformation in the process of excavations. The overload tests are accomplished under the conditions of different overburden depths. The results of this research will make certain guiding significance to the practical engineering.

  5. The transport of nonindigenous microorganisms into caves by human visitation: a case study at Carlsbad Caverns National Park

    Science.gov (United States)

    Griffin, Dale W.; Gray, Michael A.; Lyles, Michael B.; Northup, Diana E.

    2014-01-01

    A series of atmospheric investigations was conducted in Carlsbad Cavern to determine if human visitation is a possible cause for the contamination of the cave system with non-indigenous microorganisms. In 2004, site-specific culture-based data demonstrated that Staphylococcus spp. colony-forming units (CFUs) were the most prevalent members of the atmospheric community along the paved visitor trail (avg. 18.8% of CFU), while Knoellia spp. CFUs dominated off-trail locations (40.1% of CFU). Fungal culture data revealed that Penicillium and Aspergillus were prevalent in the Lunch Room where food is stored, sold, and consumed. Ubiquitous genera such as Cladosporium and Alternaria were prevalent near the Natural Entrance of the cave, and the general trend was a decrease in fungal CFUs with progression into the cave system, except for the area near the Lunch Room. Management practices such as prohibition of crumb-generating types of foods could be considered to protect cave health. In 2009, nonculture-based analyses demonstrated that Enterobacteriaceae were the dominant microbiota at sites along the descent trail and within the Lunch Room. Dominance of Enterobacteriaceae has not been previously demonstrated in caves. Either they are naturally occurring indigenous members, or their presence is a marker of anthropogenic contamination.

  6. Strategic Petroleum Reserve, West Hackberry oil storage cavern fire and spill of September 21, 1978: an environmental assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, A

    1980-02-29

    This report summarizes an environmental assessment of the fire and oil spill at the Strategic Petroleum Reserve site, West Hackberry, Louisiana. Subjective identification of oil contaminated habitats was supported by a more rigorous classification of samples utilizing discriminant analysis. Fourteen contaminated stations were identified along the shore of Black Lake just north and west of Wellpad 6, encompassing approximately 9 hectares. Seasonal variation in the structures of marsh and lake bottom communities in this contaminated area were not generally distinguishable from that of similar communities in uncontaminated habitats along the southern and southeastern shores of Black Lake. The major impact of spilled oil on the marsh vegetation was to accelerate the natural marsh deterioration which will eventually impact animals dependent on marsh vegetation for habitat structure. Vanadium, the predominate trace metal in the oil, and pyrogenic products due to the fire were found at the most distant sampling site (5 km) from Cavern 6 during Phase I, but were not detected downwind of the fire in excess of background levels in the later phases. Remote sensing evaluation of vegetation under the plume also indicated that stress existed immediately after the fire, but had disappeared by the end of the 1-year survey.

  7. Dural Venous System in the Cavernous Sinus: A Literature Review and Embryological, Functional, and Endovascular Clinical Considerations.

    Science.gov (United States)

    Mitsuhashi, Yutaka; Hayasaki, Koji; Kawakami, Taichiro; Nagata, Takashi; Kaneshiro, Yuta; Umaba, Ryoko; Ohata, Kenji

    2016-06-15

    The cavernous sinus (CS) is one of the cranial dural venous sinuses. It differs from other dural sinuses due to its many afferent and efferent venous connections with adjacent structures. It is important to know well about its complex venous anatomy to conduct safe and effective endovascular interventions for the CS. Thus, we reviewed previous literatures concerning the morphological and functional venous anatomy and the embryology of the CS. The CS is a complex of venous channels from embryologically different origins. These venous channels have more or less retained their distinct original roles of venous drainage, even after alterations through the embryological developmental process, and can be categorized into three longitudinal venous axes based on their topological and functional features. Venous channels medial to the internal carotid artery "medial venous axis" carry venous drainage from the skull base, chondrocranium and the hypophysis, with no direct participation in cerebral drainage. Venous channels lateral to the cranial nerves "lateral venous axis" are exclusively for cerebral venous drainage. Venous channels between the internal carotid artery and cranial nerves "intermediate venous axis" contribute to all the venous drainage from adjacent structures, directly from the orbit and membranous skull, indirectly through medial and lateral venous axes from the chondrocranium, the hypophysis, and the brain. This concept of longitudinal venous axes in the CS may be useful during endovascular interventions for the CS considering our better understandings of its functions in venous drainage. PMID:27063146

  8. Cryogenic fracturing of calcite flowstone in caves: theoretical considerations and field observations in Kents Cavern, Devon, UK

    Directory of Open Access Journals (Sweden)

    Lundberg Joyce

    2012-07-01

    Full Text Available Several caves in Devon, England, have been noted for extensive cracking of substantial flowstone floors. Conjectural explanations have included earthquake damage, local shock damage from collapsing cave passages, hydraulic pressure, and cryogenic processes. Here we present a theoretical model to demonstrate that frost-heaving and fracture of flowstone floors that overlie wet sediments is both a feasible and likely consequence of unidirectional air flow or cold-air ponding in caves, and argue that this is the most likely mechanism for flowstone cracking in caves located in Pleistocene periglacial environments outside of tectonically active regions. Modeled parameters for a main passage in Kents Cavern, Devon, demonstrate that 1 to 6 months of -10 to -15° C air flow at very modest velocities will result in freezing of 1 to 3 m of saturated sediment fill. The resultant frost heave increases with passage width and depth of frozen sediments. In the most conservative estimate, freezing over one winter season of 2 m of sediment in a 6-m wide passage could fracture flowstone floors up to ~13 cm thick, rising to ~23 cm in a 12-m wide passage. Natural flaws in the flowstone increase the thickness that could be shattered. These numbers are quite consistent with the field evidence.

  9. Electrical stimulation vs. pulsed and continuous-wave optical stimulation of the rat prostate cavernous nerves, in vivo

    Science.gov (United States)

    Perkins, William C.; Lagoda, Gwen A.; Burnett, Arthur; Fried, Nathaniel M.

    2015-07-01

    Identification and preservation of the cavernous nerves (CNs) during prostate cancer surgery is critical for post-operative sexual function. Electrical nerve stimulation (ENS) mapping has previously been tested as an intraoperative tool for CN identification, but was found to be unreliable. ENS is limited by the need for electrode-tissue contact, poor spatial precision from electrical current spreading, and stimulation artifacts interfering with detection. Alternatively, optical nerve stimulation (ONS) provides noncontact stimulation, improved spatial selectivity, and elimination of stimulation artifacts. This study compares ENS to pulsed/CW ONS to explore the ONS mechanism. A total of eighty stimulations were performed in 5 rats, in vivo. ENS (4 V, 5 ms, 10 Hz) was compared to ONS using a pulsed diode laser nerve stimulator (1873 nm, 5 ms, 10 Hz) or CW diode laser nerve stimulator (1455 nm). Intracavernous pressure (ICP) response and nerve compound action potentials (nCAPs) were measured. All three stimulation modes (ENS, ONS-CW, ONS-P) produced comparable ICP magnitudes. However, ENS demonstrated more rapid ICP response times and well defined nCAPs compared to unmeasurable nCAPs for ONS. Further experiments measuring single action potentials during ENS and ONS are warranted to further understand differences in the ENS and ONS mechanisms.

  10. Metachronous occurrence of nonradiation-induced brain cavernous hemangioma and medulloblastoma in a child with neurofibromatosis type I phenotype

    Directory of Open Access Journals (Sweden)

    Luciano L Furlanetti

    2012-01-01

    Full Text Available Cavernous hemangioma (CH is a sporadic vascular malformation occurring either as an autosomal dominant condition or as a well-known complication of radiation exposure. Medulloblastoma is a primitive neuroectodermal tumor common in children and currently treated with surgical resection, chemotherapy, and radiotherapy. Neurofibromatosis is the most common single-gene disorder of the central nervous system. Posterior fossa malignant tumors in the context of neurofibromatosis type I (NF1 are very infrequent. This is the first documented case of an unusual metachronous occurrence of non-radiation-induced CH and medulloblastoma in a child with NF1 phenotype. We report the case of a 13-month-old boy with cafι-au-lait skin lesions associated with NF1-like phenotype who underwent surgical resection of a single CH in the temporal lobe due to recurrent seizures. Four years later he presented with signs of raised intracranial pressure associated with a posterior fossa tumor and hydrocephalus, thus requiring gross total resection of the lesion. Histological analysis revealed a medulloblastoma. After being treated with radiotherapy and chemotherapy, he achieved total remission. Six years later a massive recurrence of the tumor was observed and the child eventually died. The interest in this case lies in the rarity of NF1-like phenotype associated with a non-radiation-induced brain CH and medulloblastoma in a child.

  11. Direct-puncture approach to the extraconal portion of the superior ophthalmic vein for carotid cavernous fistulae

    Energy Technology Data Exchange (ETDEWEB)

    Kurata, A.; Suzuki, S.; Iwamoto, K.; Miyazaki, T.; Inukai, M.; Abe, K.; Niki, J.; Yamada, M.; Fujii, K. [Kitasato University School of Medicine, Department of Neurosurgery, Kanagawa (Japan); Kan, S. [Kitasato University School of Medicine, Department of Radiology, Kanagawa (Japan)

    2009-11-15

    The transvenous approach via the superior ophthalmic vein (SOV) is an available approach for carotid cavernous fistula (CCF), especially in the event that there is no other suitable approach route to the fistula. Surgical exposure of the peripheral roots of the SOV is commonly used; however, often, the SOV is often not accessible because of anatomical problems and/or complications. In this paper, we present and discuss our original direct-puncture approach to the extraconal portion of the SOV. An attempt on three patients with traumatic CCF failed with the transarterial approach and the conventional venous approach via the inferior petrosal sinus; therefore, the patients were treated with the direct-puncture approach to the extraconal portion of the SOV using two-dimensional digital subtraction angiography with local anesthesia. All cases that had tortuous and partially stenotic division of the SOV were treated successfully with this approach and without complications. This approach will become an alternate approach, especially when the peripheral roots of the SOV are focally narrowed and tortuous, making it impossible to insert a catheter. (orig.)

  12. Direct-puncture approach to the extraconal portion of the superior ophthalmic vein for carotid cavernous fistulae

    International Nuclear Information System (INIS)

    The transvenous approach via the superior ophthalmic vein (SOV) is an available approach for carotid cavernous fistula (CCF), especially in the event that there is no other suitable approach route to the fistula. Surgical exposure of the peripheral roots of the SOV is commonly used; however, often, the SOV is often not accessible because of anatomical problems and/or complications. In this paper, we present and discuss our original direct-puncture approach to the extraconal portion of the SOV. An attempt on three patients with traumatic CCF failed with the transarterial approach and the conventional venous approach via the inferior petrosal sinus; therefore, the patients were treated with the direct-puncture approach to the extraconal portion of the SOV using two-dimensional digital subtraction angiography with local anesthesia. All cases that had tortuous and partially stenotic division of the SOV were treated successfully with this approach and without complications. This approach will become an alternate approach, especially when the peripheral roots of the SOV are focally narrowed and tortuous, making it impossible to insert a catheter. (orig.)

  13. Fractionated stereotactic radiation therapy in the management of benign cavernous sinus meningiomas. Long-term experience and review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Milker-Zabel, S.; Zabel-du Bois, A.; Debus, J. [Heidelberg Univ. (Germany). Dept. of Radiation Oncology; Huber, P. [Heidelberg Univ. (Germany). Dept. of Radiotherapy; Schlegel, W. [German Cancer Research Center, Heidelberg (Germany). Dept. of Medical Physics

    2006-11-15

    Purpose: To analyze own long-term results with fractionated stereotactic radiotherapy (FSRT) in patients with benign meningiomas of the cavernous sinus and to review the literature on these rare lesions. Patients and Methods: 57 patients were treated with FSRT for benign meningiomas of the cavernous sinus between 01/1990 and 12/2003 at the authors' institution. Histology was WHO grade I in 28/57 lesions, and undetermined in 29/57 lesions. 29 patients received radiotherapy as primary treatment, ten following surgery, and 18 patients were irradiated for recurrent disease. Median target volume was 35.2 cm{sup 3}. Median total dose was 57.6 Gy with 1.8 Gy per fraction. 51/57 patients showed clinical symptoms before radiotherapy like reduced vision (n=19), diplopia (n=25), or trigeminal hyp-/dysesthesia (n=17). Results: Median follow-up period was 6.5 years. 50/57 patients were followed for >36 months. Overall local tumor control was 100%. 39/57 patients had stable disease based on CT/MRI, while 18/57 had a partial remission of tumor volume. Overall survival for patients with WHO grade I meningiomas was 95.5% after 5 and 10 years. Two patients died 2.8 and 4.1 years after radiotherapy due to cardiac failure. In 11/57 patients, preexisting neurologic deficits improved. There was one patient with recurrent hyperlacrimation of one eye on the side of the irradiated meningioma. Three patients complained about subjective visual deterioration after FSRT without any objective findings in an ophthalmologic examination. No late toxicity RTOG{>=} III was seen. Conclusion: These data demonstrate that FSRT is an effective and safe treatment modality for local control of benign cavernous sinus meningiomas with a minimal risk of significant late toxicity. (orig.)

  14. The Role of Hemosiderin Excision in Seizure Outcome in Cerebral Cavernous Malformation Surgery: A Systematic Review and Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Di Ruan

    Full Text Available Whether the excision of hemosiderin surrounding cerebral cavernous malformations (CCMs is necessary to achieve a seizure-free result has been the subject of debate. Here, we report a systematic review of related literature up to Jan 1, 2015 including 594 patients to assess the effect of hemosiderin excision on seizure outcome in patients with CCMs by meta-analysis.Ten studies comparing extended hemosiderin excision with only lesion resection were identified by searching the English-language literature. Meta-analyses, subgroup analyses and sensitivity analysis were conducted to determine the association between hemosiderin excision and seizure outcome after surgery.Seizure outcome was significantly improved in the patients who underwent an extended excision of the surrounding hemosiderin (OR, 0.62; 95% CI: 0.42-0.91; P = 0.01. In subgroup analysis, studies from Asia (OR, 0.42; 95% CI: 0.25-0.71; P = 0.001, male-majority (female ratio 1 year before surgery (OR, 0.43; 95% CI: 0.22-0.84; P = 0.01, lesion diameter > 2 cm (OR, 0.41; 95% CI: 0.19-0.87; P = 0.02 and short-term (< 3 years follow-up (OR, 0.48; 95% CI: 0.29-0.80; P = 0.005 tended to correlate with a significantly favorable outcome.Patients who underwent extended surrounding hemosiderin excision could exhibit significantly improved seizure outcomes compared to patients without hemosiderin excision. However, further well-designed prospective multiple-center RCT studies are still needed.

  15. 2 April 2014 - H. E. Mr Joachim Gauck, President of the Federal Republic of Germany in the ATLAS experimental cavern with Director-General R. Heuer.

    CERN Multimedia

    Brice, Maximilien

    2014-01-01

    in the ATLAS cavern: Minister of State at the Federal Foreign Office M. Böhmer (green jacket) and Mrs daniela Schadt (First Lady). 201404-069_39.jpg: State Secretary, Federal Ministry of Education and Research G. Schütte, Minister of State at the Federal Foreign Office M. Böhmer, President Gauck, CERN DG, State Secretary, Chief of the Federal President´s Office D. Gill and Ambassador of the Federal Republic of Germany to the Swiss Confederation O. Lampe.

  16. 2nd February 2011-Vice-Chancellor of Jammu University-Prof. Varun Sahni-India visiting ALICE cavern and LHC Tunnel

    CERN Multimedia

    Sylvain Chapeland

    2011-01-01

    Photo 1-2,4-8:The delegation visiting the ATLAS cavern Photo 3:ALICE Collaboration Spokesperson P. Giubellino+ALICE Collaboration University of Jammu S. Mahajan+ALICE Collaboration University of Jammu A. Bhasin+ALICE Collaboration Universita degli Studi di Torino R. Bala+V. Sahni+Adviser for India R.Voss+S. Arriaga+ALICE Collaboration University of Jammu A. Gupta Photo 9-13:The delegation visiting the LHC tunnel at Point 2 Photo 14-22: Signature of the Guest Book with R. Voss

  17. Dedication of the massive ATLAS art mural painted by Josef Kristofoletti directly above the cavern of the ATLAS Experiment at CERN

    CERN Multimedia

    Claudia Marcelloni, Michael Barnett

    2010-01-01

    Ceremony to celebrate the massive mural of the ATLAS detector at CERN painted by artist Josef Kristofoletti. The mural is located at the ATLAS Experiment site, and it shows on two perpendicular walls the detector with a collision event superimposed. The event on the large wall shows a simulation of an event that would be recorded in ATLAS if a Higgs boson was produced. The cavern of the ATLAS Experiment with the detector is 100 meters directly below the mural. The height of the mural is about 12 meters (40 feet). The actual ATLAS detector is more than twice as big.

  18. Study on the planning of a demonstration plant for hydrogen fuel production by electrolysis using caching in salt caverns under pressure

    International Nuclear Information System (INIS)

    In a two year research project the long-term storage of hydrogen as energy carrier has been assessed in detail for large renewable electricity quantities in underground storage caverns in Germany. Next to a regions analysis for potential storage sites, the benchmarking against other large scale storage concepts, a comparative and perspective analysis of alkaline and PEM-electrolysers also potential business cases for Power-to-Hydrogen in the mobility sector as well as for the chemical, electricity and natural gas industry have been analysed.

  19. Ovarian Cavernous Hemangioma Presenting as a Large Growing Mass in a Postmenopausal Woman: A Case Report and Review of the Literature

    OpenAIRE

    Kim, Sun Suk; Han, Si Eun; Lee, Nam Kyung; CHOI, KYUNG UN; Joo, Jong Kil; Suh, Dong Soo; Kim, Heung Yeol; Kim, Ki Hyung

    2015-01-01

    Ovarian hemangiomas are usually of the cavernous type, and are rarely encountered. A 73-year-old woman presented with lower abdominal discomfort. Subsequent physical examination depicted a palpable mass in the lower abdomen. Abdominopelvic computed tomography (CT) revealed a well-circumscribed mass with thin septa measuring 12.1 × 9.0 cm in the right ovary. Levels of the tumor markers cancer antigen (CA)-125 and CA 19-9 were within the normal range. At laparoscopy, the tumor was found to be c...

  20. Lemierre syndrome complicated by cavernous sinus thrombosis, the development of subdural empyemas, and internal carotid artery narrowing without cerebral infarction. Case report.

    Science.gov (United States)

    Westhout, Franklin; Hasso, Anton; Jalili, Mehrdad; Afghani, Behnoosh; Armstrong, William; Nwagwu, Chiedozie; Ackerman, Laurie L

    2007-01-01

    Lemierre syndrome is an extremely rare complication of mild-to-moderate pharyngeal infections. The authors present an unusual case of Lemierre syndrome in a 16-year-old boy with cavernous sinus thrombosis and right internal carotid artery narrowing without neurological sequelae, right subdural empyema, and cerebritis in the right temporal and occipital lobes. Neuroimaging also demonstrated right jugular vein thrombosis. Cultures of samples from the blood proved positive for the presence of Fusobacterium necrophorum. The patient underwent unilateral tonsillectomy, drainage of the peritonsillar abscess, and a myringotomy on the right side. Postoperatively the patient was treated conservatively with antibiotic therapy resulting in an excellent outcome. PMID:17233314

  1. Treatment of a direct carotid-cavernous fistula in a patient with type IV Ehlers-Danlos syndrome: a novel approach

    Energy Technology Data Exchange (ETDEWEB)

    Hollands, J.K.; Santarius, T.; Kirkpatrick, P.J. [Addenbrooke' s Hospital, Department of Neurosurgery, Cambridge (United Kingdom); Higgins, J.N. [Addenbrooke' s Hospital, Department of Neuroradiology, Cambridge (United Kingdom)

    2006-07-15

    We report a case of a 34-year-old female with type IV Ehlers-Danlos syndrome diagnosed with a carotid cavernous fistula presenting with progressive proptosis. Endovascular embolization using balloons or coils carries a high risk of complications in this group of patients, owing to the extreme fragility of the blood vessels. Initial treatment was conservative until an intracerebral haemorrhage occurred. To avoid transfemoral angiography, the ipsilateral carotid arteries and the internal jugular vein were surgically exposed for insertion of two endovascular sheaths. The patient was transferred from theatre to the angiography suite and the sheaths were used for embolization access. The fistula was closed, with preservation of the carotid artery, using Guglielmi detachable coils deployed in the cavernous sinus from the arterial and venous sides. Rapid resolution of symptoms and signs followed, which was sustained at 6-month follow-up. This technique offers alternative access for endovascular treatment, which may reduce the high incidence of mortality associated with catheter angiography in this condition. (orig.)

  2. Cavernous body reduction in four patients with erectile dysfunction due to insufficient venous occlusion and a deficit of elastic fibers in the tunica albugínea

    Directory of Open Access Journals (Sweden)

    Fabrizio Iacono

    2007-12-01

    Full Text Available INTRODUCTION: The corpora cavernosa are cylindrical vessels containing fluid under pressure. Thus, if cavernous wall resistance decreases, the radius increases and internal pressure decreases (LaPlace's law. We reasoned that if we decrease the corpus cavernosum radius, by excising a strip from each tunica albuginea, intracavernous pressure would increase during erection. MATERIALS AND METHODS: We treated with this procedure, four patients (mean age 41.5 with long-standing erectile dysfunction due to veno-occlusive dysfunction, non-responders to phosphodiesterase-5 inhibitors and intracavernous PGE1 injection. RESULTS: Two months post-surgery, intracavernous PGE1 (40 mcg induced a satisfactory erection in two patients and a 45% and 58% tumescence in the other two. PGE1 responders also responded to 100 mg sildenafil. After 100 mg sildenafil and 20 mg tadalafil, the two non-responders had erections that enabled penetration but were short lasting. CONCLUSION: The procedure described could be more effective than cavernous revascularization operations. The results seem to confirm the mathematical assumptions.

  3. ATLAS cavern hand-over ceremony on 4th June 2003 in the presence of the President of the Swiss Confederation

    CERN Document Server

    Jenni, P

    The 4th of June 2003 will be remembered as a very major milestone in the history of the ATLAS detector construction. In the presence of the President of the Swiss Confederation, Mr. Pascal Couchepin, the ATLAS cavern was handed over by the CERN Director-General, Professor Luciano Maiani, to the Collaboration. For this highly press-mediated event the CERN Director-General had invited some 100 political personalities and representatives from the Geneva and the neighbouring French regions, and from CERN Member and Non-Member States. The surface building was transformed for this occasion into an attractive multi- media hall with films and exhibitions from ATLAS and the civil engineering, with a bar and the CERN jazz band. Besides of course the cavern itself, the Swiss President visited also the ATLAS barrel toroid magnet and the LAr calorimeter assembly activities in Hall 180. The Swiss President visiting the Barrel Toroid integration work in Hall 180 He was very interested and impressed by these, aski...

  4. Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1

    Science.gov (United States)

    Choquet, Hélène; Trapani, Eliana; Goitre, Luca; Trabalzini, Lorenza; Akers, Amy; Fontanella, Marco; Hart, Blaine L.; Morrison, Leslie A.; Pawlikowska, Ludmila; Kim, Helen; Retta, Saverio Francesco

    2016-01-01

    Background Familial Cerebral Cavernous Malformation type 1 (CCM1) is an autosomal dominant disease caused by mutations in the Krev Interaction Trapped 1 (KRIT1/CCM1) gene, and characterized by multiple brain lesions. CCM lesions manifest across a range of different phenotypes, including wide differences in lesion number, size and susceptibility to intracerebral hemorrhage (ICH). Oxidative stress plays an important role in cerebrovascular disease pathogenesis, raising the possibility that inter-individual variability in genes related to oxidative stress may contribute to the phenotypic differences observed in CCM1 disease. Here, we investigated whether candidate oxidative stress-related cytochrome P450 (CYP) and matrix metalloproteinase (MMP) genetic markers grouped by superfamilies, families or genes, or analyzed individually influence the severity of CCM1 disease. Methods Clinical assessment and cerebral susceptibility-weighted magnetic resonance imaging (SWI) were performed to determine total and large (≥5 mm in diameter) lesion counts as well as ICH in 188 Hispanic CCM1 patients harboring the founder KRIT1/CCM1 ‘common Hispanic mutation’ (CCM1–CHM). Samples were genotyped on the Affymetrix Axiom Genome-Wide LAT1 Human Array. We analyzed 1,122 genetic markers (both single nucleotide polymorphisms (SNPs) and insertion/deletions) grouped by CYP and MMP superfamily, family or gene for association with total or large lesion count and ICH adjusted for age at enrollment and gender. Genetic markers bearing the associations were then analyzed individually. Results The CYP superfamily showed a trend toward association with total lesion count (P=0.057) and large lesion count (P=0.088) in contrast to the MMP superfamily. The CYP4 and CYP8 families were associated with either large lesion count or total lesion count (P=0.014), and two other families (CYP46 and the MMP Stromelysins) were associated with ICH (P=0.011 and 0.007, respectively). CYP4F12 rs11085971, CYP8A

  5. 以癫痫发作为主的脑内海绵状血管畸形的手术治疗%Surgical Treatment of Cerebral Cavernous Malformation Presenting Epileptic Seizures

    Institute of Scientific and Technical Information of China (English)

    周峰; 吴俊; 彭磊; 王硕; 桑林; 郑重; 解飞; 葛留锁; 马延山

    2014-01-01

      结论对于合并癫痫的海绵状血管畸形患者应早期进行手术。术中应完整切除海绵状血管畸形病灶(包括病灶周边的胶质瘢痕层和含铁血黄素层),同时行皮层热灼术。%Objective To provide effective surgical methods for patients with cavernous malformation complicated with epilepsy. Methods Twenty-seven patients with cavernous malformation complicated with epilepsy in our department were retrospectively analyzed. Simultaneously, we compared different epilepsy prognosis and other relevant factors between patients accepted total resection (including the gliotic and hemosiderin-stained brain tissue adjacent to the lesions) and patients accepted total resection combined with cortex thermocoagulation. Results ① Prognosis of patients treated with total resection combined with cortex thermocoagulation was much better than those who only accepted total resection (P=0.036). ②Prognosis of patients whose course of epilepsy is less than 1 year was much better than those whose course is more than 1 year (P=0.022).③There were no statistical signiifcances for epilepsy prognosis in sex, age, the lobe where the cavernous malformation located, different epilepsy seizures, whether preoperative application of antiepileptic drugs (AEDs) and postoperative Karnofsky Performance Status Scale (KPS). Conclusion The analysis of outcome showed that patients with cavernous malformation complicated with epilepsy beneifted signiifcantly from early surgery. And at the same time, in order to achieve better effect from the surgery, total resection of cavernous malformation (including the gliotic hemosiderin-stained brain tissue adjacent to the lesions) must be adopted, and cortex thermocoagulation treatment should be applied.

  6. Heat and Mass Transfer and Creep in Underground Oil Storage with Cavern%盐穴地下储油库热质交换及蠕变

    Institute of Scientific and Technical Information of China (English)

    卜宪标; 谭羽非; 李炳熙; 宋传亮

    2009-01-01

    To ensure cavern tightness and safety, the models of heat transfer between oil, brine and surrounding rock, thermal pressurization rate, halite creep, and seepage were established and TDMA algorithm was adopted to solve them. The results suggest that the temperature and the pressure will increase by 8. 635℃ and 8.97 MPa in seven years storage process, respectively, i. e. , an approximate value of 1 MPa/℃. The creep rate will decrease with the increase in storage time, and the penetration could be neglected due to little penetrability. In addition, temperature will have significant influence on the cavern pressure and the influence will be determined by the ratio between the thermal expansion coefficient and the compressibility factor (α/β) of both oil and brine. It appears that the thermal expansion coefficient and the compressibility factor of both oil and brine should be measured precisely so that the liquid temperature and pressure in caverns can be predicted accurately.%为了确保盐穴储油库的密闭性和安全性,建立了油、卤水和围岩的热交换模型以及由于温度变化而引起的溶腔压力变化模型,同时建立了岩盐蠕变和渗透模型.通过TDMA算法对模型进行了求解,结果表明,油在7 a的放置过程中,温度升高了8.635℃,压力升高了8.97 MPa,即温度升高1℃压力约升高1 MPa.另外,盐穴的蠕变量随着放置时间的增加而减小.岩盐的渗透率很小,油的渗透量可以忽略.温度变化对溶腔压力有重要的影响,油和卤水的热膨胀系数与可压缩系数的比值决定了温度变化对压力的影响程度.在实际注油时,要准确测量油和卤水的可压缩系数和热膨胀系数,以便对溶腔内液体的温度和压力做出正确的预测和判断.

  7. Brainstem Cavernous Angioma

    Science.gov (United States)

    ... in significant, and potentially life-threatening, symptoms. The nerves that transverse the brainstem control basic, involuntary functions such as respiration, gag reflex, heartbeat regulation, body temperature, pain and heat sensation, ...

  8. Cerebral Cavernous Malformations (CCM)

    Science.gov (United States)

    ... such as weight loss, daily exercise, improvement in sleep hygiene, avoidance of triggers or to advise on medical ... lifestyle changes (weight loss, daily exercise, improvement in sleep hygiene, avoidance of triggers), medications for symptomatic relief, or ...

  9. Ovarian cavernous hemangioma.

    Science.gov (United States)

    Alvarez, M; Cerezo, L

    1986-01-01

    Vascular tumors of the female genital tract are rare, especially those of the ovary. Most cases are small lesions that are discovered incidentally. We describe a 68-year-old woman with a benign hemangioma that presented clinically as a very large ovarian mass. PMID:3753575

  10. Spinal extradural cavernous angioma

    International Nuclear Information System (INIS)

    The clinical case of a white 57 year-old patient is presented, with clinical pattern of dorsal medullary compression, reason why a laminectomy of D5-D7 was carried out, with resection of an extradural, rounded, wine colored lesion, of 3x2x2 cm. The results of the biopsy confirmed the diagnosis of an angiomatous malformation (cavernoma). Surgery is the ideal treatment for these types of lesions and the spine magnetic resonance is an useful study to diagnose and to treat those affected

  11. Cavernous hemangioma of the Ilium mimicking aggressive malignant bone tumor with increased activity on 18F-FDG PRT/CT

    International Nuclear Information System (INIS)

    Osseous hemangioma is a benign vascular tumor, and it usually occurs in the vertebrae and the skull. However, hemangiomas of flat bones are rare, and there are very few reports that describe the radiologic findings of osseous hemangioma of the ilium. We report a unique case of large cavernous hemangioma mimicking a chondrogenic malignant bone tumor originated from the ilium in a 22-year-old female. The mass showed stippled calcifications, heterogeneous enhancement with thick septa and enhanced soft tissue components on CT and MR, and also this mass demonstrated heterogeneous 2-fluoro [fluorine-18]-2-deoxy-D-glucose (18F-FDG) uptake on 18F-FDG PET/CT.

  12. Fístula carótido-cavernosa com epistaxe letal: relato de caso Carotid-cavernous fistula with lethal epistaxis: case report

    Directory of Open Access Journals (Sweden)

    Rover Borba

    2001-06-01

    Full Text Available A fístula carótido-cavernosa é uma comunicação patológica entre a artéria carótida interna e o seio cavernoso. Apresentamos o caso de um paciente de 32 anos de idade com fístula carótido-cavernosa devida a traumatismo crânio-encefálico. O tratamento preconizado é a embolização mas neste caso em especial houve falha devido às características próprias da fístula, e o paciente progrediu de maneira desfavorável evoluindo ao óbito por epistaxe incontrolável.We report the case of a 32 years old male patient with carotid-cavernous fistula caused by head injury who died from massive epistaxis. Treatment assesment of this case is faced with the literature.

  13. Estimation of low energy neutron flux (En ≤ 15 MeV) in India-based Neutrino Observatory cavern using Monte Carlo techniques

    International Nuclear Information System (INIS)

    The neutron flux at low energy (En ≤ 15 MeV) resulting from the radioactivity of the rock in the underground cavern of the India-based Neutrino Observatory is estimated using Geant4-based Monte Carlo simulations. The neutron production rate due to the spontaneous fission of 235, 238U, 232Th and (α, n) interactions in the rock is determined employing the actual rock composition. It is shown that the total flux is equivalent to a finite size cylindrical rock (D=L=140 cm) element. The energy integrated neutron flux thus obtained at the center of the underground tunnel is 2.76 (0.47) × 10−6 n cm−2 s−1. The estimated neutron flux is of the same order (∼10−6 n cm−2 s−1) as measured in other underground laboratories

  14. Estimation of low energy neutron flux ($E_n\\leq15$ MeV) in India-based Neutrino Observatory cavern using Monte Carlo techniques

    CERN Document Server

    Dokania, N; Mathimalar, S; Garai, A; Nanal, V; Pillay, R G; Bhushan, K G

    2015-01-01

    The neutron flux at low energy ($E_n\\leq15$ MeV) resulting from the radioactivity of the rock in the underground cavern of the India-based Neutrino Observatory is estimated using Geant4-based Monte Carlo simulations. The neutron production rate due to the spontaneous fission of U, Th and ($\\alpha, n$) interactions in the rock is determined employing the actual rock composition. It has been demonstrated that the total flux is equivalent to a finite size cylindrical rock ($D=L=140$ cm) element. The energy integrated neutron flux thus obtained at the center of the underground tunnel is 2.76 (0.47) $\\times 10^{-6}\\rm~n ~cm^{-2}~s^{-1}$. The estimated neutron flux is of the same order ($\\sim10^{-6}\\rm~n ~cm^{-2}~s^{-1}$)~as measured in other underground laboratories.

  15. State of the art for fabricating and emplacing concrete containers into large horizontal disposal caverns in the french geological repository - 59267

    International Nuclear Information System (INIS)

    The research and development work presented in this paper was initialized by Andra in 2007. The work necessary for manufacturing and testing a full scale demonstrator is presently implemented. The case story is twofold. The first part is related to the initial development of a high performance concrete formulation used for fabricating concrete storage containers (containing Intermediate Level and Long Lived Waste primary canisters) to be stacked and emplaced into 400-m long concrete lined horizontal disposal vaults (also called cavern), excavated in the Callovo-Oxfordian clay host formation at a 550 to 600-m depth, with an inside diameter of approximately 8-m. The fabrication of the concrete boxes is illustrated. The second part presents the outcome at the end of the detailed design phase, for a system which is now being manufactured (for further test and assembly), for the emplacement of the concrete containers inside the vault. The application was engineered for remote emplacing a pile of 2 concrete containers (the containers are preliminarily stacked in a pile of 2, inside a hot cell, thanks to a ground travelling gantry crane). The emplacement process is justified and the related emplacement synoptic is illustrated. The test campaign is scheduled in 2011-2012. The successful completion of the technical trials is mandatory to confirm the mechanical feasibility of remotely emplacing concrete containers into large horizontal disposal caverns over long distances. The later display of the machinery at work in Andra's showroom will be instrumental for the confidence building process involving the various stakeholders concerned by the public enquiry period (mid-2013) preceding the deep geological repository license application (2014-2015). (authors)

  16. Brainstem cavernous malformations: a review with two case reports Malformações cavernosas do tronco cerebral: uma revisão com relato de dois casos

    Directory of Open Access Journals (Sweden)

    Adolfo Ramírez-Zamora

    2009-09-01

    Full Text Available Central nervous system (CNS cavernous malformations (CMs are developmental malformations of the vascular bed with a highly variable clinical course due to their dynamic nature. We present one case of "de novo" brainstem cavernous malformation after radiation therapy adding to the increasing number of reported cases in the medical literature, and the case of a pregnant patient with symptomatic intracranial hemorrhage related to brainstem CMs to illustrate the complex nature in management of these patients, followed by a review of clinical and radiographic characteristics. CMs account for 8-15% of all intracranial and intraspinal vascular malformations. Although traditionally thought to be congenital in origin, CMs may present as acquired lesions particularly after intracranial radiation therapy. Clinical manifestations are protean and surgical treatment should be considered for patients with progressive neurologic deficits.Malformações cavernosas (MFC do sistema nervoso central são malformações do desenvolvimento do leito vascular com múltiplas apresentações clínicas devido a sua natureza dinâmica. Apresentamos dois casos de malformações cavernosas do tronco cerebral: o primeiro após radioterapia e o segundo em paciente grávida com hemorragia intracraniana sintomática. MFC são responsáveis por cerca de 8-15% de todas as malformações vasculares. Embora tradicionalmente sejam genéticas, as MFC podem também ser adquiridas, particularmente após radioterapia. As manifestações clínicas são variáveis e o tratamento cirúrgico deve ser considerado para pacientes com quadros neurológicos progressivos.

  17. Complex carotid cavernous sinus fistulas Barrow type D: endovascular treatment via the ophthalmic vein, imaging control with standardized MRI, long-term results

    International Nuclear Information System (INIS)

    Purpose: Since feeding arteries from both the internal and external carotid artery are common, cavernous fistulas of Barrow type D are difficult to treat. Embolization using the transarterial approach is considered to be the standard therapy. However, it is often impossible to embolize feeders from the internal carotid artery. The transorbital approach after anterior orbitotomy through the ophthalmic vein is an alternative in this complex situation. The following reports our experience with three female patients who underwent transvenous embolization. Procedural success was documented using standardized MRI and clinical reevaluation. Materials and Methods: Three female patients between 57 and 78 years of age were diagnosed with carotid cavernous fistulas by conventional angiogram. All patients were suffering from exophthalmus and visual impairment. Two patients showed secondary glaucoma and diplopia. In one patient we performed a technically successful transarterial embolization using particles, but no relevant improvement of the patient's condition was seen. Transfemoral transvenous access via the sinus petrosus was not possible in any patient. All patients were then embolized via the ophthalmic vein using GDC detachable coils. All patients were clinically reevaluated by an ophthalmologist. Also a standardized MRI was performed for documentation. Follow-up was performed for the first patient for 32 months, for the second patient for 34 months and for the third patient for 50 months. Results: Transvenous embolization was technically successful in all three cases. Clinical symptoms disappeared rapidly. Postprocedural MRI showed a symmetric diameter of the ophthalmic vein. Venous congestion of the orbit caused by fatty tissue edema regressed completely. Contrast-enhanced magnetic resonance angiography showed normal arterial vessels without evidence of fistula. (orig.)

  18. Cavernous nerves innervation from prostate apex to distal penis%海绵体神经在前列腺尖部及远端的行程与分布

    Institute of Scientific and Technical Information of China (English)

    李俊; 黄健; 虞湘才; 黄海

    2009-01-01

    目的 观察海绵体神经在前列腺尖部及其远端的行程和分布,探讨海绵体神经与周围 组织的关系.方法 3具成年男性尸体尿道和阴茎标本,自前列腺尖部至阴茎头连续切片行HE染色和神经纤维嗜银染色,观察海绵体神经在前列腺尖部及其远端尿道膜部阴茎的行程与分布.结果 海绵体神经纤维束行于前列腺尖部和尿道膜部约3点到9点处,距离尿道腔约3~5 mm,向远端进入阴茎海绵体近段.自尿道膜部向前走行与海绵体静脉丛并行进入海绵体中隔.结论 海绵体神经在前列腺尖部以及阴茎近段与尿道及海绵体静脉关系密切,该部位尿道和海绵体静脉相关手术容易损伤海绵体神经.%Objective To investigate the cavernous nerves innervation from prostate apex to glans penis and the relation between cavernous nerves and surrounding tissues and organs. Methods The urethra and penises of three formalin preserved adult cadavers were removed from prostate apex to glans penis.The sections underwent hematoxylin-eosin staining and Bielschowsky nerve staining.The course and distribution of cavernous nerves and relationship between the cavernous nerves and surrounding tissues and organs was observed microscopically and photographed from prostate apex to glans penis. Results From serial sections we found when nerve fibres run along prostate apex,while surrounding the lateral and dorsal aspects of prostate apex and urethra.from 30'clock to 9 0'clock.Most fibres went through smooth muscle and some of them went through the periphery striated muscle and urogenital diaphragm.The distance to urethra lumen was only 3-5 mm.After the nerve fibres went distally and anteriorly,they accompanied closely with cavernous vein plexus and then went into corpora cavernosa.At the distal end of corpora cavernosa,there were"windows"through which the neurovascular bundles communicated between corpora cavernosa and glans penis just like doors to glans

  19. Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion.

    Science.gov (United States)

    Hannan, Johanna L; Matsui, Hotaka; Sopko, Nikolai A; Liu, Xiaopu; Weyne, Emmanuel; Albersen, Maarten; Watson, Joseph W; Hoke, Ahmet; Burnett, Arthur L; Bivalacqua, Trinity J

    2016-01-01

    Axonal injury due to prostatectomy leads to Wallerian degeneration of the cavernous nerve (CN) and erectile dysfunction (ED). Return of potency is dependent on axonal regeneration and reinnervation of the penis. Following CN injury (CNI), RhoA and Rho-associated protein kinase (ROCK) increase in penile endothelial and smooth muscle cells. Previous studies indicate that nerve regeneration is hampered by activation of RhoA/ROCK pathway. We evaluated the role of RhoA/ROCK pathway in CN regulation following CNI using a validated rat model. CNI upregulated gene and protein expression of RhoA/ROCK and caspase-3 mediated apoptosis in the major pelvic ganglion (MPG). ROCK inhibitor (ROCK-I) prevented upregulation of RhoA/ROCK pathway as well as activation of caspase-3 in the MPG. Following CNI, there was decrease in the dimer to monomer ratio of neuronal nitric oxide synthase (nNOS) protein and lowered NOS activity in the MPG, which were prevented by ROCK-I. CNI lowered intracavernous pressure and impaired non-adrenergic non-cholinergic-mediated relaxation in the penis, consistent with ED. ROCK-I maintained the intracavernous pressure and non-adrenergic non-cholinergic-mediated relaxation in the penis following CNI. These results suggest that activation of RhoA/ROCK pathway mediates caspase-3 dependent apoptosis of nitrergic neurons in the MPG following CNI and that ROCK-I can prevent post-prostatectomy ED. PMID:27388816

  20. Diffuse cavernous hemangioma of the rectum: an atypical cause of rectal bleeding Hemangioma cavernoso difuso del recto: una causa atípica de hemorragia digestiva baja

    Directory of Open Access Journals (Sweden)

    D. Hervías

    2004-05-01

    Full Text Available Objective: cavernous hemangioma of the rectosigmoid colon is a rare disease, with no more than 200 cases reported in the literature. The rectosigmoid is the most common site of this disease in the gastrointestinal tract. Case report: we report the case of a 31-year-old male with recurrent episodes of rectal bleeding, who was finally diagnosed of diffuse cavernous hemangioma of the rectum. The tumor, of 12 x 10 x 9 cm in size, occupied the rectum to the margin of the anal sphincter. A surgical procedure was ruled out because of the inability to carry out a safe anastomosis while preserving anal sphincters. Discussion: rectal hemangiomas are less frequent vascular malformations. The clinical presentation of a cavernous hemangioma of the rectum is usually acute, recurrent or chronic rectal bleeding. Other symptoms stem from the possible compression or invasion of adjacent structures, such as lumbar or perianal pain, metrorrhage, hematuria, etc. This diagnosis is commonly made in younger patients. Colonoscopy is without doubt the diagnostic technique of choice, and it allows to establish the localization, morphology, and total extension of the lesion; its characteristic image is a red-purplish nodule with great vascular congestion. According to the opinion of most authors, biopsy is not advisable during colonoscopy, since imaging techniques are sufficient for an accurate diagnosis, and the risk of bleeding while manipulating this lesion is not negligible. Computed tomography and particularly magnetic resonance imaging, given their high precision to delimit the lesion and its relations to adjacent structures, are imaging studies that are mandatory before surgical treatment. Other techniques such as selective angiography, barium enema, gastrointestinal transit, and upper-tract endoscopy may be supplementary and help locate more lesions along the gastrointestinal tract. Failure to recognize the exact diagnosis and extent of diffuse cavernous hemangioma

  1. Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history

    International Nuclear Information System (INIS)

    To retrospectively investigate the prevalence, MR findings, natural history, and association with other hepatic lesions of focal nodular hyperplasia (FNH)-like lesions in a cohort of consecutive patients with cavernous transformation of the portal vein (CTPV). This retrospective IRB-approved study comprised 58 patients (32 men, 26 women; average age, 50 years) with CTPV who underwent liver MR imaging between 2000 and 2008. MR images were assessed by two radiologists in consensus for the presence of (a) FNH-like lesions and other liver lesions, and (b) other imaging findings. Patients were assigned to a stable or progressive clinical course based on lesion characteristics at follow-up. Twelve of 58 patients (21%) had 38 FNH-like lesions (average size, 1.3 cm). Common findings of FNH-like lesions were isointensity on T2-weighted images (82%), intense and homogeneous enhancement during the arterial phase, and lack of washout during the hepatic venous and interstitial phases (100%). FNH-like lesions were found with other benign liver lesions (1 hemangioma, 1 adenoma) in two patients. Three (25%) patients with FNH-like lesions showed a progressive clinical course. FNH-like lesions are commonly detected in patients with CTPV. Most lesions demonstrate benign imaging findings and stable clinical course. (orig.)

  2. Focal nodular hyperplasia-like lesions in patients with cavernous transformation of the portal vein: prevalence, MR findings and natural history

    Energy Technology Data Exchange (ETDEWEB)

    Marin, Daniele [Duke University Medical Center, Department of Radiology, Durham, NC (United States); University of Rome Sapienza, Department of Radiological Sciences, Rome (Italy); Galluzzo, Anna; Brancatelli, Giuseppe [Universita di Palermo, Istituto di Radiologia, Palermo (Italy); Plessier, Aurelie; Valla, Dominique [Service d' Hepatologie, Hopital Beaujon, Clichy (France); Vilgrain, Valerie [Assistance Publique des Hopitaux de Paris, APHP, Hopital Beaujon, Department of Radiology, Clichy (France); Universite Paris 7 Denis Diderot, Paris (France)

    2011-10-15

    To retrospectively investigate the prevalence, MR findings, natural history, and association with other hepatic lesions of focal nodular hyperplasia (FNH)-like lesions in a cohort of consecutive patients with cavernous transformation of the portal vein (CTPV). This retrospective IRB-approved study comprised 58 patients (32 men, 26 women; average age, 50 years) with CTPV who underwent liver MR imaging between 2000 and 2008. MR images were assessed by two radiologists in consensus for the presence of (a) FNH-like lesions and other liver lesions, and (b) other imaging findings. Patients were assigned to a stable or progressive clinical course based on lesion characteristics at follow-up. Twelve of 58 patients (21%) had 38 FNH-like lesions (average size, 1.3 cm). Common findings of FNH-like lesions were isointensity on T2-weighted images (82%), intense and homogeneous enhancement during the arterial phase, and lack of washout during the hepatic venous and interstitial phases (100%). FNH-like lesions were found with other benign liver lesions (1 hemangioma, 1 adenoma) in two patients. Three (25%) patients with FNH-like lesions showed a progressive clinical course. FNH-like lesions are commonly detected in patients with CTPV. Most lesions demonstrate benign imaging findings and stable clinical course. (orig.)

  3. Familial form of cerebral cavernous malformations: evaluation of gradient-spin-echo (GRASE) imaging in lesion detection and characterization at 1.5 T

    International Nuclear Information System (INIS)

    The purpose of this study was to evaluate the turbo gradient-spin-echo sequence (GRASE) in the MR assessment of the familial form of cerebral cavernous malformations (CCM). Twenty-one patients (15 male, six female) aged from 21 to 68 years (mean = 42.2 years) were prospectively examined with cerebral MR imaging, including T2-weighted turbo gradient-spin-echo (TGSE), turbo spin-echo (TSE) and gradient-echo (GRE) sequences. All sequences were performed in the same plane, the same matrix and the same field of view and were analyzed for signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), susceptibility effects, number of CCM, size of CCM and signal of CCM. It was found that SNR and CNR in the TGSE sequence were significantly inferior to those in both TSE and GRE sequences. TGSE and TSE sequences were significantly less prone to susceptibility effects than the GRE sequence. The sensitivity of TGSE and TSE sequences in detecting CCM was significantly lower than that of the GRE sequence. TGSE and TSE sequences provided comparable information about CCM size and signal. It was concluded that GRASE imaging was less sensitive than the GRE sequence in the detection of CCM and provided information similar to that yielded by the TSE sequence in the characterization of lesions, but with a higher number of artifacts. GRASE imaging cannot therefore replace TSE or GRE sequences in the MR evaluation of the familial form of CCM. (orig.)

  4. BP Canada energy company ethane cavern well fires Fort Saskatchewan, Alberta August/September 2001 : EUB Post-incident report April 2002

    International Nuclear Information System (INIS)

    A natural gas liquids (NGL) plant, located approximately 6 kilometres northeast of Fort Saskatchewan, Alberta, is operated by BP Canada Energy Company (BP). A pipeline is used to deliver the products to several locations in Alberta, eastern Canada, and the United States, and the products are stored on site. A two-inch line connecting two wellheads that service one of the storage caverns experienced the failure of an elbow on August 26, 2001. Subsequent investigations indicated that unusual transverse forging defects were the source of the elbow failure. Conventional testing methods would not have detected such defects. The consequence of this failure was the release of ethane product into the atmosphere. An ethane vapour plume was created, and it ignited upon contact with overhead power lines at the plant site. All access roads to and from the plant were immediately secured and there were no injuries to plant personnel. The emergency response plan developed by BP was activated and the facility was shut down. The public was not threatened in any way nor was their property even though the black smoke from the fire could be seen from far away. Well control operations were expedited through the cooperation of officials from the Alberta Energy and Utilities Board (EUB), Alberta Environment, local authorities and BP. Emissions of soot were the primary environmental impact and the provincial air quality guidelines were not exceeded. A review of the events indicate that local emergency response personnel reacted quickly to the situation in the appropriate manner although the expectations from the public were not met concerning early public notification. Equipment design changes have been effected to prevent reoccurrence. 4 figs

  5. 大型地下水封洞库施工顺序优化%Excavation sequence analysis of underground water-seal petroleum storage caverns

    Institute of Scientific and Technical Information of China (English)

    郭伟

    2012-01-01

    A method of side pressure coefficient of describing geostatic stress is used to invert initial ground stress.Based on measured data of initial ground stress,the side pressure coefficient is obtained by regression analysis.The excavation sequence and construction method of underground petroleum storage caverns are simulated by using numerical method.The result shows that the deformation and plastic zone of rock mass are nearly the same under two ways of excavation: three-layer excavation and four-layer excavation.The separate excavation way is superior to the parallel and successive excavation way.The space between of working faces should be greater than 40 m.%采用侧压系数法对某大型地下水封洞库地应力进行了反演分析,运用回归反演的初始地应力场对储油主洞室进行了施工开挖分层及施工顺序的优化分析.分析结果表明,储油主洞室分三层和分四层两种开挖方式对岩体位移和塑性区分布范围影响都不大;跳挖开挖方式优于平行开挖和依次开挖方式,在施工工期许可的条件下宜按照跳挖开挖方式进行,各洞室开挖掌子面间距宜控制在40m以上.

  6. Detailed imaging of the normal anatomy and pathologic conditions of the cavernous region at 3 Tesla using a contrast-enhanced MR angiography

    International Nuclear Information System (INIS)

    The purpose of this study was to evaluate the potential of a high-resolution contrast-enhanced magnetic resonance angiography (CE-MRA) at 3 Tesla for the delineation of the cavernous sinus (CS) anatomy both under normal and under pathological conditions. Fifteen patients without pathologies in the CS and ten patients with pituitary adenomas were included. The CE-MRA was performed on a 3-Tesla scanner and analyzed collaboratively by two readers. The cranial nerves (CNs) within the CS, namely CNIII, CNIV, CNV1, CNV2, and CNVI, were identified in both patient groups. In the adenoma patients it was also assessed whether and to which extend the adenoma invaded the CS and the spatial relationship between tumor and CNs was determined. In the patients with normal CS anatomy, CNIII could be identified in 100%, CNIV in 86.7%, and CNV1, CNV2, as well as CNVI in 100% of analyzed sides. Pituitary adenomas invaded the CS unilaterally (right side) in four patients, and bilaterally in six patients. In patients with adenomas, the CN could be identified and differentiated from the tumor in the following percentages: CNIII in 100%, CNIV in 70%, both CNV1 and CNV2 in 90%, and CNVI in 100%. In all these cases, the tumor-nerve spatial relationship could be visualized. 3-Tesla CE-MRA allows detailed imaging of the complex anatomy of the CS and its structures. In adenoma patients, it clearly visualizes the spatial relationship between tumor and CNs, and thus might be helpful to optimize presurgical planning. (orig.)

  7. AB211. Effect of early chronic low-dose tadalafil administration on erectile dysfunction after cavernous nerve injury in the rat model

    Science.gov (United States)

    Bian, Jun; Liu, Cundong; Yang, Jiankun; Zhou, Qizhao; Sun, Xiangzhou; Deng, Chunhua

    2016-01-01

    Objective To investigate the effect of early chronic tadalafil administration on erectile dysfunction after cavernous nerve (CN) injury in the rat model. Methods Using the CN crush injury model, animals were divided into four groups: no CN injury (sham), bilateral CN injury exposed to either no tadalafil (control) or tadalafil at a dose (2 mg/kg) daily postoperation for 4 weeks, and normal group. At the time point, we assessed erectile function by apomorphine test, measurement of maximum intracavernosal pressure (ICP)/mean arterial pressure (MAP) ratio with major pelvic ganglion (MPG) electrical stimulation. For the histological analyses, the mid-shaft of penis were harvested. Immunohistochemical antibody staining was performed for nNOS and the numbers of nNOS-positive nerve fibers were recorded. Results Penile erection was observed in 50% (6/12) of the rats for (1.13±0.92) times within 30 min in control group, as compared with 0% (0/11) of the rats for (0.00±0.00) times in CN crush group (P0.05), while ICP/MAP ratio after MPG electrical stimulation of control group was significantly higher than that of CN crush group (P<0.05), but significantly lower than that of sham group (P<0.05) and normal group (P<0.05). The numbers of nNOS-positive nerve fibers was significantly larger in control group than in CN crush group (54.11±5.02 vs. 21.34±3.17, P<0.05), but was significantly smaller than that of sham group (76.48±8.24, P<0.05) and normal group (81.09±7.25, P<0.05). Conclusions Early chronic low-dose tadalafil administration on erectile dysfunction after CN injury contributes to restoration of erectile function.

  8. Energy restriction and exercise modulate angiopoietins and vascular endothelial growth factor expression in the cavernous tissue of high-fat diet-fed rats

    Institute of Scientific and Technical Information of China (English)

    In(ě)s Tomada; Nuno Tomada; Henrique Almeida; Delminda Neves

    2012-01-01

    The purpose of the current study was to evaluate the effect of a high-fat (HF) diet,energy restriction and exercise on the expression of vascular endothelial growth factor (VEGF),angiopoietin (Ang) 1 and 2,and their receptors in rat corpus cavernosum (CC).Male Wistar rats were fed adlibitum with an HF diet for 8 or 16 weeks.After 8 weeks of the HF diet,a group of rats was subjected to energy restriction with or without exercise for 8 weeks.Control animals had free access to standard diet for the same period.After euthanasia,blood was collected and the penises removed for immunofluorescence assays (VEGF,VEGF receptor (VEGFR) 1 and 2,Ang1,Ang2 and Tie2) and semiquantification of VEGF,VEGFR1,VEGFR2,Ang1,Ang2,Tie2,endothelial nitric oxide synthase (eNOS) and Akt/phospho-Akt by Western blotting.HF diet-fed rats exhibited lower high-density lipoprotein cholesterol (HDL-c) levels,higher systolic blood pressure and an increased atherogenic index.A significant increase in Ang2 expression in the CC was verified and coupled to a decrease in VEGF and VEGFRs.The Akt pathway was activated by the HF diet.Energy restriction and exercise increased eNOS expression and restored most HF diet-induced modifications except for VEGFR2 expression.These results emphasize the role of diet on vascular function regulation,demonstrating that cavernous imbalance of VEGF/VEGFRs and Angs/rie2 systems occurs before serum lipid changes and obesity onset,antedating structural atherosclerotic features.

  9. Detailed imaging of the normal anatomy and pathologic conditions of the cavernous region at 3 Tesla using a contrast-enhanced MR angiography

    Energy Technology Data Exchange (ETDEWEB)

    Linn, Jennifer; Peters, Friederike; Lummel, Nina; Brueckmann, Hartmut; Yousry, Indra [University Hospital Munich, Department of Neuroradiology, Munich (Germany); Schankin, Christoph [University Hospital Munich, Department of Neurology, Munich (Germany); Rachinger, Walter [University Hospital Munich, Department of Neurosurgery, Munich (Germany)

    2011-12-15

    The purpose of this study was to evaluate the potential of a high-resolution contrast-enhanced magnetic resonance angiography (CE-MRA) at 3 Tesla for the delineation of the cavernous sinus (CS) anatomy both under normal and under pathological conditions. Fifteen patients without pathologies in the CS and ten patients with pituitary adenomas were included. The CE-MRA was performed on a 3-Tesla scanner and analyzed collaboratively by two readers. The cranial nerves (CNs) within the CS, namely CNIII, CNIV, CNV1, CNV2, and CNVI, were identified in both patient groups. In the adenoma patients it was also assessed whether and to which extend the adenoma invaded the CS and the spatial relationship between tumor and CNs was determined. In the patients with normal CS anatomy, CNIII could be identified in 100%, CNIV in 86.7%, and CNV1, CNV2, as well as CNVI in 100% of analyzed sides. Pituitary adenomas invaded the CS unilaterally (right side) in four patients, and bilaterally in six patients. In patients with adenomas, the CN could be identified and differentiated from the tumor in the following percentages: CNIII in 100%, CNIV in 70%, both CNV1 and CNV2 in 90%, and CNVI in 100%. In all these cases, the tumor-nerve spatial relationship could be visualized. 3-Tesla CE-MRA allows detailed imaging of the complex anatomy of the CS and its structures. In adenoma patients, it clearly visualizes the spatial relationship between tumor and CNs, and thus might be helpful to optimize presurgical planning. (orig.)

  10. Staged endovascular treatment with selective EC-IC bypass for symptomatic large-giant aneurysms in the cavernous portion of the internal carotid artery

    International Nuclear Information System (INIS)

    For the treatment of symptomatic large-giant aneurysm in the cavernous portion of the internal carotid artery (ICA), it is often necessary to occlude the ICA with or without extracranial-intracranial (EC-IC) bypass surgery. We report 11 patients with such symptomatic lesions treated between January 2004 and June 2008 by staged endovascular trapping of the aneurysm with detachable coils following selective EC-IC bypass placement. The necessity of the bypass was determined according to neurological conditions and radiological findings during the preoperative balloon test occlusion (BTO) of the ICA. When ischemic symptoms occurred during BTO, high-flow bypass was selected. Otherwise, findings on single-photon emission computed tomography were used for the bypass selection. Following completion of the bypass, dual antiplatelet therapy was induced. Then the confirmative BTO and endovascular ICA occlusion (ICA-O) under local anesthesia were planned several days after the bypass placement. A total of 4 high-flow bypasses with radial artery graft were placed before ICA-O, while 7 patients underwent endovascular ICA-O without bypass surgery. There were no perioperative complications related to the procedures in 10 cases, but 1 developed cerebral infarction 7 days after bypass placement possibly due to distal embolism from intraaneurysmal thrombus. No patients showed postoperative symptoms according to insufficient ipsilateral cerebral blood flow, and cranial nerve palsies improved in all patients. Favorable outcomes can be expected for patients with such aneurysms by staged endovascular ICA-O with selective EC-IC bypass. Although endovascular ICA-O can be safe and useful, understanding of adequate antithrombotic therapy and treatment timing are especially important in cases with bypass placement. (author)

  11. High-resolution micro-CT for morphologic and quantitative assessment of the sinusoid in human cavernous hemangioma of the liver.

    Directory of Open Access Journals (Sweden)

    Jinghao Duan

    Full Text Available Hepatic sinusoid plays a vital role in human cavernous hemangioma of the liver (CHL, and its morphologic investigation facilitates the understanding of microcirculation mechanism and pathological change of CHL. However, precise anatomical view of the hepatic sinusoid has been limited by the resolution and contrast available from existing imaging techniques. While liver biopsy has traditionally been the reliable method for the assessment of hepatic sinusoids, the invasiveness and sampling error are its inherent limitations. In this study, imaging of CHL samples was performed using in-line phase-contrast imaging (ILPCI technique with synchrotron radiation. ILPCI allowed clear visualization of soft tissues and revealed structural details that were invisible to conventional radiography. Combining the computed tomography (CT technique, ILPCI-CT was used to acquire the high-resolution micro-CT images of CHL, and three dimensional (3D microstructures of hepatic sinusoids were provided for the morphologic depiction and quantitative assessment. Our study demonstrated that ILPCI-CT could substantially improve the radiographic contrast of CHL tissues in vitro with no contrast agent. ILPCI-CT yielded high-resolution micro-CT image of CHL sample at the micron scale, corresponding to information on actual structures revealed at histological section. The 3D visualization provided an excellent view of the hepatic sinusoid. The accurate view of individual hepatic sinusoid was achieved. The valuable morphological parameters of hepatic sinusoids, such as thrombi, diameters, surface areas and volumes, were measured. These parameters were of great importance in the evaluation of CHL, and they provided quantitative descriptors that characterized anatomical properties and pathological features of hepatic sinusoids. The results highlight the high degree of sensitivity of the ILPCI-CT technique and demonstrate the feasibility of accurate visualization of hepatic

  12. 10th February 2011-Ambassador Permanent Representative of the Republic of Ecuador to the United Nations H.E. Mr Mauricio Montalvo visiting CMS cavern with Head of International Relations F. Pauss

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Photo 1,9-50:the delegation visiting the CMS cavern Photo 2-8:visiting CMS Control room Photo 51:V. Aguilar,First Secretary-G. Tonelli,CMS Collaboration Spokesperson-M. Montalvo-L. Sulak,CMS Collaboration-M. del Carmen Vivar,Third Secretary-N. Mora,Personal Assistant of Ambassador-B. Jones,Information Technology Department, EU Projects-L. Vayas,Counsellor-F. Pauss-J. Carlos Sánchez,First Secretary-J. Salicio,Adviser for Ecuador Photo 52-59:M.Montalvo signing the Guest Book with F. Pauss

  13. Intra-arterial embolization with pingyangmycin-lipiodol emulsion for the treatment of hepatic cavernous hemangioma: an analysis of factors affecting therapeutic results

    International Nuclear Information System (INIS)

    Objective: To analyze the factors that might affect the therapeutic results of pingyangmycin-lipiodol emulsion intra-arterial sclerosing embolization (PLE-IASE) in treating symptomatic cavernous hemangioma of liver (SCHL). Methods: PLE-IASE was performed in 89 patients with SCHL (32 males and 57 females). Before treatment the mean diameter of the hemangioma was (8.3±3.8) cm. Of 89 patients, 53 experienced anxiety, 35 suffered from right upper abdominal pain and the remaining one developed Kasabach-Merrit syndrome. Before PLE-IASE, the arteriographic classification was conducted based on hepatic arteriographic findings. Then pingyangmycin-lipiodol emulsion (PLE) was injected through the feeding artery. The dosage of pingyangmycin (PYM) was (9.8 ± 4.4) mg and the dosage of lipiodol (LP) was (5.9 ± 2.9) ml. The lipiodol deposition status was judged by the follow-up spot film taken immediately after PLE-IASE. The observations of the occurrence of complications, the relief of symptoms and the minification of SCHL were followed for 6-72 months after PLE-IASE. The linear regression analysis statistics was conducted by taking the minification as dependent variable and taking the arteriographic classification, lipiodol deposition status, the dosage of PYM, the dosage of lipiodol and the preoperative SCHL diameter as independent variable. Results: Of all 89 cases of SCHL, hypervascular type was seen in 51, hypovascular type in 26 and arteriovenous shunt (AVS) type in 12. Good lipiodol deposition status was found in 64 patients and poor deposition in 25 patients after PLE-IASE. After PLE-IASE, the symptom of anxiety in 53 patients was relieved and the right upper abdominal pain was reduced in 33 cases although intermittent pain still remained in 2 patients. The blood platelet count of the patient with Kasabach-Merrit syndrome returned to normal after the treatment. The symptomatic relieve rate was 98.7%. No serious complications occurred in the follow-up period. The linear

  14. 28 March 2014 - Italian Minister of Education, University and Research S. Giannini welcomed by CERN Director-General R. Heuer and Director for Research and Scientific Computing S. Bertolucci in the ATLAS experimental cavern with Former Collaboration Spokesperson F. Gianotti. Signature of the guest book with Belgian State Secretary for the Scientific Policy P. Courard.

    CERN Multimedia

    Gadmer, Jean-Claude

    2014-01-01

    28 March 2014 - Italian Minister of Education, University and Research S. Giannini welcomed by CERN Director-General R. Heuer and Director for Research and Scientific Computing S. Bertolucci in the ATLAS experimental cavern with Former Collaboration Spokesperson F. Gianotti. Signature of the guest book with Belgian State Secretary for the Scientific Policy P. Courard.

  15. 3 February 2011 - British Members of the Science and Technology Committee (Commons)led by A. Miller MP signing the guest book with CERN Director for Accelerators and Technology S. Myers; in the ATLAS experimental cavern at LHC Point 1 with Spokesperson F. Gianotti and Deputy D. Charlton.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    3 February 2011 - British Members of the Science and Technology Committee (Commons)led by A. Miller MP signing the guest book with CERN Director for Accelerators and Technology S. Myers; in the ATLAS experimental cavern at LHC Point 1 with Spokesperson F. Gianotti and Deputy D. Charlton.

  16. 24 May 2013 - Rector of the Polish Stanislaw Staszic AGH University of Science and Technology T. Slomka in the LHC tunnel at Point 8 with Senior Polish Staff Member A. Siemko, in LHCb experimental cavern with LHCb Collaboration Spokesperson P. Campana and signing the guest book with Director-General R. Heuer. Adviser for Eastern Europe T. Kurtyka present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    24 May 2013 - Rector of the Polish Stanislaw Staszic AGH University of Science and Technology T. Slomka in the LHC tunnel at Point 8 with Senior Polish Staff Member A. Siemko, in LHCb experimental cavern with LHCb Collaboration Spokesperson P. Campana and signing the guest book with Director-General R. Heuer. Adviser for Eastern Europe T. Kurtyka present.

  17. 1 October 2013 - British Minister of State for Trade and Investment Lord Green of Hurstpierpoint signing the guest book with Head of Internationals Relations R. Voss; visiting the LHC tunnel at Point 1 and the ATLAS experimental cavern with ATLAS Collaboration Members K. Behr and J. Catmore.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    1 October 2013 - British Minister of State for Trade and Investment Lord Green of Hurstpierpoint signing the guest book with Head of Internationals Relations R. Voss; visiting the LHC tunnel at Point 1 and the ATLAS experimental cavern with ATLAS Collaboration Members K. Behr and J. Catmore.

  18. Senior Senator from Florida and Chairman, Senate Committee on Space, Aeronautics and Related Sciences W. Nelson, visiting the ATLAS cavern and LHC tunnel with ATLAS Collaboration Spokesperson P. Jenni and AMS Collaboration Spokesperson S.C.C.Ting, 16 March 2008.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    Senior Senator from Florida and Chairman, Senate Committee on Space, Aeronautics and Related Sciences W. Nelson, visiting the ATLAS cavern and LHC tunnel with ATLAS Collaboration Spokesperson P. Jenni and AMS Collaboration Spokesperson S.C.C.Ting, 16 March 2008.

  19. 22. August 2013 - Permanent Representative of the Republic of Korea to the United Nations Office and other international organizations in Geneva, Ambassador Extraordinary and Plenipotentiary S. Choi signing the guest book with Director-General R. Heuer; visiting the LHC tunnel with P. Fessia and the CMS experimental cavern with Former Collaboration Spokesperson J. Virdee.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    22. August 2013 - Permanent Representative of the Republic of Korea to the United Nations Office and other international organizations in Geneva, Ambassador Extraordinary and Plenipotentiary S. Choi signing the guest book with Director-General R. Heuer; visiting the LHC tunnel with P. Fessia and the CMS experimental cavern with Former Collaboration Spokesperson J. Virdee.

  20. 17 April 2013 - UK Queen Mary University London Principal S. Gaskell in the ATLAS control room at LHC Point 1, LHC tunnel and ATLAS experimental cavern with Collaboration Spokesperson D. Charlton and signing the guest book with CERN Director for Accelerators and Technology S. Myers.

    CERN Document Server

    Maximilien Brice

    2013-01-01

    17 April 2013 - UK Queen Mary University London Principal S. Gaskell in the ATLAS control room at LHC Point 1, LHC tunnel and ATLAS experimental cavern with Collaboration Spokesperson D. Charlton and signing the guest book with CERN Director for Accelerators and Technology S. Myers.

  1. 9 April 2013 - Minister for Universities and Science United Kingdom of Great Britain and Northern Ireland D. Willetts in the ATLAS experimental cavern with ATLAS Collaboration Spokesperson D. Charlton and in the LHC tunnel at Point 1 with Beams Department Head P. Collier. Director for Accelerators and Technology S. Myers, Editor at the Communication Group K. Kahle and Beams Department Engineer R. Veness present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    9 April 2013 - Minister for Universities and Science United Kingdom of Great Britain and Northern Ireland D. Willetts in the ATLAS experimental cavern with ATLAS Collaboration Spokesperson D. Charlton and in the LHC tunnel at Point 1 with Beams Department Head P. Collier. Director for Accelerators and Technology S. Myers, Editor at the Communication Group K. Kahle and Beams Department Engineer R. Veness present.

  2. 17 October 2013 - C. Ashton High Representative of the European Union for Foreign Affairs and Security Policy, Vice-President of the European Commission visiting the ATLAS cavern with ATLAS Collaboration Spokesperson D. Charlton; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest book with CERN Director-General R. Heuer.

    CERN Multimedia

    Maximilien Brice

    2013-01-01

    17 October 2013 - C. Ashton High Representative of the European Union for Foreign Affairs and Security Policy, Vice-President of the European Commission visiting the ATLAS cavern with ATLAS Collaboration Spokesperson D. Charlton; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest book with CERN Director-General R. Heuer.

  3. 1er février 2011-Première Présidente de la Confédération Suisse (1999)-Mme Ruth Dreifuss-Visite de la caverne expérimentale d’ATLAS avec F. Pauss, Chef des Relations internationales

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Photo 1-24:Collaboration ATLAS, Ancien Porte-parole P. Jenni+F. Pauss+Experte en pédagogie S. Forster+R. Dreifuss+C. Bossy+JP Bossy, visite de la caverne ATLAS Photo 25-40:Visite du Tunnel LHC au Point 1

  4. 8 April 2013 - Indian Hon'ble Minister for Ministry of Science & Technology and Ministry of Earth Sciences Shri Sudini Jaipal Reddy in the LHC tunnel with K. Foraz, visiting the CMS cavern with Technical Coordinator A. Ball and Former Spokesperson T. Virdee, signing the guest book with Director-General R. Heuer.

    CERN Multimedia

    Samuel Morier-Genoud

    2013-01-01

    8 April 2013 - Indian Hon'ble Minister for Ministry of Science & Technology and Ministry of Earth Sciences Shri Sudini Jaipal Reddy in the LHC tunnel with K. Foraz, visiting the CMS cavern with Technical Coordinator A. Ball and Former Spokesperson T. Virdee, signing the guest book with Director-General R. Heuer.

  5. Tuesday 28 January 2014 - K. E. Huthmacher Ministerialdirektor Provision for the Future - Basic and Sustainability Research Federal Ministry of Education and Research (BMBF) visiting the stands with R. Heuer CERN Director-General on the occasion of the Inauguration of the Industrial Exhibition Germany@CERN and visiting the ATLAS Cavern with D. Charlton ATLAS Collaboration Spokesperson and R. Voss Head of International Relations.

    CERN Multimedia

    Pantelia, Anna

    2014-01-01

    Tuesday 28 January - K. E. Huthmacher Ministerialdirektor Provision for the Future - Basic and Sustainability Research Federal Ministry of Education and Research (BMBF) visiting the stands with R. Heuer CERN Director-General on the occasion of the Inauguration of the Industrial Exhibition Germany@CERN and visiting the ATLAS Cavern with D. Charlton ATLAS Collaboration Spokesperson and R. Voss Head of International Relations.

  6. 22 May 2013 - Turkish Minister of Health M. Müezzinoğlu signing the guest book with Director-General R. Heuer; in the LHC tunnel at Point 5 with International Relations Adviser E. Tsesmelis; in CMS experimental cavern with Deputy Spokesperson T. Camporesi. Turkish Scientists S. A. Cetin and B. Demirkoz present.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    22 May 2013 - Turkish Minister of Health M. Müezzinoğlu signing the guest book with Director-General R. Heuer; in the LHC tunnel at Point 5 with International Relations Adviser E. Tsesmelis; in CMS experimental cavern with Deputy Spokesperson T. Camporesi. Turkish Scientists S. A. Cetin and B. Demirkoz present.

  7. 8 May 2013 - Swedish European Spallation Source Chief Executive Officer J. H. Yeck in the ATLAS visitor centre and experimental cavern with Collaboration Spokesperson D. Charlton (also present M. Nessi, R. Garoby and E. Tsesmelis); signing the guest book with International Relations Adviser E. Tsesmelis.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    8 May 2013 - Swedish European Spallation Source Chief Executive Officer J. H. Yeck in the ATLAS visitor centre and experimental cavern with Collaboration Spokesperson D. Charlton (also present M. Nessi, R. Garoby and E. Tsesmelis); signing the guest book with International Relations Adviser E. Tsesmelis.

  8. 5 June 2013 - Sri Lankan Senior Minister of Scientific Affairs T. Vitharana signing the guest book with Director-General R. Heuer, in the LHC tunnel at Point 5 with International Relations Adviser R. Voss and in the CMS cavern with CERN Team leader A. Petrilli.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    5 June 2013 - Sri Lankan Senior Minister of Scientific Affairs T. Vitharana signing the guest book with Director-General R. Heuer, in the LHC tunnel at Point 5 with International Relations Adviser R. Voss and in the CMS cavern with CERN Team leader A. Petrilli.

  9. 25 April 2012 - Latvia Riga Technical University Rector L. Ribickis signing the guest book with CERN Director-General R. Heuer and visiting the LHC tunnel at Point 5 and CMS experimental cavern with Deputy Spokesperson T. Camporesi and Adviser for the Republic of Latvia T. Kurtyka.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    25 April 2012 - Latvia Riga Technical University Rector L. Ribickis signing the guest book with CERN Director-General R. Heuer and visiting the LHC tunnel at Point 5 and CMS experimental cavern with Deputy Spokesperson T. Camporesi and Adviser for the Republic of Latvia T. Kurtyka.

  10. 21 January 2008 - Vice-President of the Human Rights Commission Z. Muhsin Al Hussein, Ambassador to United Nations A. Attar and their delegation from Saudi Arabia, visiting the ATLAS experimental cavern with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

    CERN Document Server

    Claudia Marcelloni

    2008-01-01

    21 January 2008 - Vice-President of the Human Rights Commission Z. Muhsin Al Hussein, Ambassador to United Nations A. Attar and their delegation from Saudi Arabia, visiting the ATLAS experimental cavern with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

  11. 21 May 2013 - Slovakian State Secretary, Ministry of Health V. Čislák signing the Guest Book with CERN Director-General R. Heuer; in the LHC tunnel at Point 2 with V. Senaj (Technology Department); in the ALICE experimental cavern with P. Chochula (Physics Department). M. Cirilli (Knowledge Transfer Group) present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    21 May 2013 - Slovakian State Secretary, Ministry of Health V. Čislák signing the Guest Book with CERN Director-General R. Heuer; in the LHC tunnel at Point 2 with V. Senaj (Technology Department); in the ALICE experimental cavern with P. Chochula (Physics Department). M. Cirilli (Knowledge Transfer Group) present.

  12. 5 June 2013 - European Union Ambassador to Switzerland and the Principality of Liechtenstein R. Jones in the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, in the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the guest book with Director-General R. Heuer. Head of the EU Projects Office S. Stavrev present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    5 June 2013 - European Union Ambassador to Switzerland and the Principality of Liechtenstein R. Jones in the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, in the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the guest book with Director-General R. Heuer. Head of the EU Projects Office S. Stavrev present.

  13. 16 December 2013 - Hooke Professor of Experimental Physics and Pro Vice Chancellor University of Oxford Prof. I. Walmsley visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, Physics Department, ATLAS Collaboration P. Wells and Chair, CMS Collaboration Board, Oxford University and Purdue University I. Shipsey

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    16 December 2013 - Hooke Professor of Experimental Physics and Pro Vice Chancellor University of Oxford Prof. I. Walmsley visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, Physics Department, ATLAS Collaboration P. Wells and Chair, CMS Collaboration Board, Oxford University and Purdue University I. Shipsey

  14. 7 May 2013 - Ambassador of the Federal Republic of Germany to Switzerland and Liechtenstein P. Gottwald and Mrs Gottwald in the ATLAS experimental cavern and LHC tunnel with Collaboration Deputy Spokesperson T. Wengler and German Scientists A. Schopper and V. Mertens.

    CERN Multimedia

    Maximilien Brice

    2013-01-01

    7 May 2013 - Ambassador of the Federal Republic of Germany to Switzerland and Liechtenstein P. Gottwald and Mrs Gottwald in the ATLAS experimental cavern and LHC tunnel with Collaboration Deputy Spokesperson T. Wengler and German Scientists A. Schopper and V. Mertens.

  15. 30 August 2013 - Senior Vice Minister for Foreign Affairs in Japan M. Matsuyama signing the guest book with CERN Director-General; visit the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton and visiting the LHC tunnel at Point 1 with former ATLAS Japan national contact physicist T. Kondo. R. Voss and K. Yoshida present throughout.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    30 August 2013 - Senior Vice Minister for Foreign Affairs in Japan M. Matsuyama signing the guest book with CERN Director-General; visit the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton and visiting the LHC tunnel at Point 1 with former ATLAS Japan national contact physicist T. Kondo. R. Voss and K. Yoshida present throughout.

  16. 12 December 2013 - Sir Konstantin Novoselov, Nobel Prize in Physics 2010, signing the guest book with International Relations Adviser E. Tsesmelis; visiting the ATLAS experimental cavern with Spokesperson D. Charlton; in the LHC tunnel with Technology Department Head F. Bordry. I. Antoniadis, CERN Theory Group Leader, accompanies throughout.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    12 December 2013 - Sir Konstantin Novoselov, Nobel Prize in Physics 2010, signing the guest book with International Relations Adviser E. Tsesmelis; visiting the ATLAS experimental cavern with Spokesperson D. Charlton; in the LHC tunnel with Technology Department Head F. Bordry. I. Antoniadis, CERN Theory Group Leader, accompanies throughout.

  17. 29 November 2013 - U. Humphrey Orjiako Nigerian Ambassador Extraordinary and Plenipotentiary Permanent Mission to the United Nations Office and other international organisations in Geneva signing the Guest Book with Head of International Relations R. Voss, visiting the LHC tunnel at Point 2 and the ALICE cavern with ALICE Collaboration Deputy Spokesperson Y. Schutz.

    CERN Multimedia

    Noemi Caraban

    2013-01-01

    29 November 2013 - U. Humphrey Orjiako Nigerian Ambassador Extraordinary and Plenipotentiary Permanent Mission to the United Nations Office and other international organisations in Geneva signing the Guest Book with Head of International Relations R. Voss, visiting the LHC tunnel at Point 2 and the ALICE cavern with ALICE Collaboration Deputy Spokesperson Y. Schutz.

  18. 16 Augur 2013 -Bulgarian Minister of Education and Sciences A. Klisarova visiting the LHC tunnel with S. Russenschuck and CMS experimental cavern with Deputy Spokesperson T. Camporesi and V. Genchev ; signing the guest book with CERN Director-General R. Heuer. Accompanied throughout by P. Hristov, L. Litov, R. Voss and Z. Zaharieva.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    16 Augur 2013 -Bulgarian Minister of Education and Sciences A. Klisarova visiting the LHC tunnel with S. Russenschuck and CMS experimental cavern with Deputy Spokesperson T. Camporesi and V. Genchev ; signing the guest book with CERN Director-General R. Heuer. Accompanied throughout by P. Hristov, L. Litov, R. Voss and Z. Zaharieva.

  19. Mr Lars Leijonborg, Minister for Higher Education and Research of Sweden visiting the cavern ATLAS, the control room of ATLAS and the machine LHC at Point 1 with Collaboration Spokesperson P. Jenni and Dr. Jos Engelen, Chief Scientific Officer of CERN.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    Mr Lars Leijonborg, Minister for Higher Education and Research of Sweden visiting the cavern ATLAS, the control room of ATLAS and the machine LHC at Point 1 with Collaboration Spokesperson P. Jenni and Dr. Jos Engelen, Chief Scientific Officer of CERN.

  20. 17 September 2013 - Estonian Minister of Education and Research J. Aaviksoo signing the guest book with CERN Director-General R- Heuer; visiting the TOTEM facility with TOTEM Collaboration Spokesperson S. Giani; in the LHC tunnel at Point 5 with International Relations Adviser T. Kurtyka and visiting the CMS cavern with CMS Collaboration Spokesperson J. Incandela. International Relations Adviser R. Voss present.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    17 September 2013 - Estonian Minister of Education and Research J. Aaviksoo signing the guest book with CERN Director-General R- Heuer; visiting the TOTEM facility with TOTEM Collaboration Spokesperson S. Giani; in the LHC tunnel at Point 5 with International Relations Adviser T. Kurtyka and visiting the CMS cavern with CMS Collaboration Spokesperson J. Incandela. International Relations Adviser R. Voss present.

  1. 16 July 2013 - Israel Ministry of Education Director-General D. Stauber in the LHC tunnel at Point 1 with L. Tavian, visiting the ATLAS experimental cavern with Senior Physicist G. Mikenberg; Israeli Delegate to CERN Council E. Rabinovici and CERN Adviser for Israel E. Tsesmelis present; signing the guest book with CERN Director-General R. Heuer.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    16 July 2013 - Israel Ministry of Education Director-General D. Stauber in the LHC tunnel at Point 1 with L. Tavian, visiting the ATLAS experimental cavern with Senior Physicist G. Mikenberg; Israeli Delegate to CERN Council E. Rabinovici and CERN Adviser for Israel E. Tsesmelis present; signing the guest book with CERN Director-General R. Heuer.

  2. 6 November 2013 - Permanent Representative of Chile to the United Nations Office and Other international organizations in Geneva Ambassador J. Balmaceda Serigos signing the guest book with Adviser for Latin America J. Salicio Diez; visiting the ATLAS experimental cavern with Spokesperson D. Charlton (Spouse, Son and First Secretary present).

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    6 November 2013 - Permanent Representative of Chile to the United Nations Office and Other international organizations in Geneva Ambassador J. Balmaceda Serigos signing the guest book with Adviser for Latin America J. Salicio Diez; visiting the ATLAS experimental cavern with Spokesperson D. Charlton (Spouse, Son and First Secretary present).

  3. 23 July - Italian Director-General for Prevention G. Ruocco and Director-General for European and International Relations Ministry of Health D. Roderigo visiting the ATLAS experimental cavern with ATLAS Deputy Spokesperson B. Heinemann. Life Sciences Section M. Cirilli and Life Sciences Adviser M. Dosanjh present.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    23 July - Italian Director-General for Prevention G. Ruocco and Director-General for European and International Relations Ministry of Health D. Roderigo visiting the ATLAS experimental cavern with ATLAS Deputy Spokesperson B. Heinemann. Life Sciences Section M. Cirilli and Life Sciences Adviser M. Dosanjh present.

  4. 13 September 2013 - Chairman of the Board of Directors of the von Karman Institute Kingdom of Belgium J.-P. Contzen visiting the ATLAS experimental cavern with ATLAS Former Spokesperson P. Jenni; visiting the LHC tunnel at Point 1 with Technology Department N. Delruelle and signing the guest book with Technology Department Head F. Bordry. International Relations Adviser T. Kurtyka present.

    CERN Document Server

    Laurent Egli (visit)

    2013-01-01

    13 September 2013 - Chairman of the Board of Directors of the von Karman Institute Kingdom of Belgium J.-P. Contzen visiting the ATLAS experimental cavern with ATLAS Former Spokesperson P. Jenni; visiting the LHC tunnel at Point 1 with Technology Department N. Delruelle and signing the guest book with Technology Department Head F. Bordry. International Relations Adviser T. Kurtyka present.

  5. 19 September 2011 - Austrian State Secretary for European and International Affairs W. Waldner, signing the guest book with Head of International Relations F. Pauss; visiting CMS service cavern with Collaboration Spokesperson G. Tonelli and the LHC superconducting magnet test hall with M. Zerlauth.

    CERN Multimedia

    Benoît Jeannet

    2011-01-01

    Austrian state secretary for foreign affairs, Wolfgang Waldner, left, was welcomed to CERN by Felicitas Pauss, head of international relations at CERN, on 19 September. While at CERN, he toured the CMS control room and underground experimental service cavern, the LHC superconducting magnet test hall, and the Universe of Particles exhibition in the Globe of Science and Innovation.

  6. 18 February 2013 - Foundation for Polish Science President M. Zylicz signing the guest book with CERN Director for Research and Scientific Computing S. Bertolucci; visiting the ALICE experimental cavern with K. Safarik and L. Graczykowskind LHC tunnel with Technology Department A. Siemko.

    CERN Multimedia

    Samuel Morier-Genoud

    2013-01-01

    18 February 2013 - Foundation for Polish Science President M. Zylicz signing the guest book with CERN Director for Research and Scientific Computing S. Bertolucci; visiting the ALICE experimental cavern with K. Safarik and L. Graczykowskind LHC tunnel with Technology Department A. Siemko.

  7. 19 July 2013 - Chairman of the Policy Committee, European Cancer Organisation, President, European Association for Cancer Research E. Celis visiting the ATLAS experimental cavern with ATLAS Collaboration Deputy Spokesperson, B. Heinemann and signing the Guest Book with Director for Accelerators and Technology S. Myers. Life Sciences Adviser M. Dosanjh present.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    19 July 2013 - Chairman of the Policy Committee, European Cancer Organisation, President, European Association for Cancer Research E. Celis visiting the ATLAS experimental cavern with ATLAS Collaboration Deputy Spokesperson, B. Heinemann and signing the Guest Book with Director for Accelerators and Technology S. Myers. Life Sciences Adviser M. Dosanjh present.

  8. 16 December 2013 - P. Lavie President of the Technion Institute of Technology in Israel visiting the ATLAS cavern with ATLAS Deputy Spokesperson T. Wengler; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest Book with CERN Director-General R. Heuer. G. Mikenberg, E. Rabinovici, Y. Rozen and S. Tarem present throughout.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    16 December 2013 - P. Lavie President of the Technion Institute of Technology in Israel visiting the ATLAS cavern with ATLAS Deputy Spokesperson T. Wengler; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest Book with CERN Director-General R. Heuer. G. Mikenberg, E. Rabinovici, Y. Rozen and S. Tarem present throughout.

  9. Hhcy大鼠阴茎海绵体内cAMP,cGMP含量及研究%The Study about cAMP and cGMP in the Penile Corpus Cavernous of Hyper Homocysteine Rats

    Institute of Scientific and Technical Information of China (English)

    王贵平; 李明; 张万峰; 王洪杰; 丁晓晖; 刘会恩

    2011-01-01

    Objective:To detect the levels of camp,cgmp in the penile corpus cavernous of adult male Wistar rats with high homocysteine and to explore the relationship of camp and cgmp with erectile dysfunction.Methods:Forty wistar rats were divided into a control and an Hhcy group.The control group were fed on normal diet and Hhcy group were fed diet with 3% methionine respectively.Four weeks later,the Wistar rats were detected by injecting apomorphine,the levels of camp and cgmp in the penile corpus cavenous were detect and that of serum homocysteine by the cycle enzyme method.Results:Compared with the control group,the levels of camp and cgmp in the penile corpus cavernous of the Hhcy group were significantly lower,while homocysteine was significantly higher.Conclusion:The levels of camp and cgmp in the penile corpus cavernous in Wistar rats with high homocysteine is lower.Hhcy is an significantly risk factor of erectile dysfunction.%目的:探讨高同型半胱氨酸血症大鼠阴茎海绵体组织内cAMP,cGMP含量的变化并研究其对阴茎勃起功能影响.方法:取40只成年雄性大鼠,随机分成两组,分为正常对照组和Hhcy组.Hhcy组给予3%高蛋氨酸饲料喂养,正常组给予普通饲料喂养,饲养四周后后分别注射阿扑吗啡进行大鼠阴茎勃起功能实验,抽取血清检测Hhcy含量,麻醉后取阴茎海绵体测量cAMP,cGMP含量.结果:Hhcy组血清中同型半胱氨酸含量显著高于正常组,大鼠阴茎组织中cAMP,cGMP含量显著低于正常组.结论:高同型半胱氨酸血症大鼠阴茎海绵体中cAMP,cGMP含量降低.高同型半胱氨酸血症是阴茎勃起功能障碍的危险因素.

  10. Cerebral Cavernous Malformation and Hemorrhage

    Science.gov (United States)

    ... patients and this could contribute to predisposition to hemorrhagic stroke. Extreme stimulants such as cocaine and other illicit drugs have been shown to cause brain hemorrhages among patients without prior ... even after a hemorrhagic event. Should symptoms suddenly appear, don't delay ...

  11. gigapanorama of NA 62 cavern

    CERN Multimedia

    Brice, Maximilien

    2015-01-01

    The image shows the new rare Kaon decay experiment at CERN, called NA62. The NA62 experiment is 270 metres long and includes a 120-metre-long vacuum tank, shown here, housing several of the particle detectors. (Note: the experiment axis is a straight line, the curving of the tank is an optical effect of the photo.) Kaons are particles that decay into lighter elementary particles. The kaon decay processes are mostly well known, except for some very rare decay modes. For example, NA62 is investigating a rare decay predicted by the Standard Model in which a kaon decays into one pion and two neutrinos. This process occurs only once every 10 billion decays. The understanding of such ultra-rare decays are of great importance because they test the Standard Model in energy ranges not accessible by direct measurements. They are therefore complementary to the measurements at the LHC. ultra high definition on demand (photolab@cern.ch).

  12. CT Diagnosis of Cavernous Hemangioma of the Occipital Bone(A Report of 6 Cases)%枕骨海绵状血管瘤CT诊断(附6例报告)

    Institute of Scientific and Technical Information of China (English)

    杨春燕; 张新民; 王济源

    2004-01-01

    枕骨海绵状血管瘤(occipital bone cavernous angiomas.OCA)较为少见,由于本病无明显临床定位体征,诊断较为困难。在CT影像应用临床之前,传统的X线是其最基本的检查方法,但存在着一定的局限性及不足之处。CT对本病的报道甚少。笔者就经CT发现,手术及病理证实的6例此病报道如下,旨在提高对此病的认识,掌握基本的CT表现。

  13. 8th February 2011-Rector Universidad Autónoma de Sinaloa Mexico Dr Victor Antonio Corrales Burgeño-Mexico-visiting ALICE cavern and tunnel with ALICE Spokesperson P. Giubellino

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Photo 1,3-14:The delegation visiting ALICE cavern Photo 2:Dra. Beatriz E. Rodríguez Pérez\tDirectora del Centro de Políticas de Género para la igualdad entre Hombres y Mujeres,Dr Victor Antonio Corrales Burgeño,P. Giubellino Photo 15-29:The delegation visiting LHC Tunnel Photo 30-57:Signature of the Guest Book with CERN Director-General R. Heuer and Head of International Relations F. Pauss Photo 58:Adviser for Mexico J. Salicio,ALICE Collaboration Universidad Autonoma de Sinaloa I. Leon Monzon,ALICE Collaboration Centro Invest. Estudios Avanz. IPN (Cinnestav) G. Herrera Corral,R. Heuer,Dr Victor Antonio Corrales Burgeño,F. Pauss,Dra. Beatriz E. Rodríguez Pérez,Directora de Relaciones InternacionalesMC. América M. Lizárraga González

  14. Fundamental studies on storage in saline caverns of thickened chemical and toxic waste, especially incinerator ash. Final report and summary; Grundlagenuntersuchungen zum Dickstoffverfahren mit chem./tox. Abfaellen, insbesondere MVA-Filteraschen, im Salinar. Zusammenfassender Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Kecke, H.J. (ed.)

    2001-07-01

    Waste incineration produces about three quarters of slag and one quarter of ash. While the slag can be recycled after treatment, e.g. as roadway construction material, the dust is stored in salt caverns. Problems can be avoided by hydraulic transport and flushing, or by hydromechanization, i.e. mixing incinerator dust with a carrier fluid and binder. The thickened material will fill the cavern completely without requiring compressing. To make this process efficient, detailed analyses of the residue materials of waste incineration are required.d. [German] Die Restmasse bei der Muellverbrennung umfasst dann etwa zu dreiviertel Schlacke und zu etwa einem Viertel Asche bzw. Staeube aus der Rauchgasreinigung. Die Schlacke kann nach einer weiteren Behandlung einer Nutzung zugefuehrt werden; vor allem kommt sie als Verkehrsweg-Unterbau zum Einsatz. Fuer die Staeube bietet sich die Einlagerung in gegebene Hohlraeume des Salzbergbaues an. Bei der Einlagerung untertage sollte eine weitere Konvergenz der Hohlraeume weitgehend unterbunden werden. Dies ist bei einer Schuettung (mechanische Einbringung, Blasversatz) mit einem Lueckenvolumen von etwa 40% z.T. gegeben. Auch erfordert das Handling mit staubfoermigen Stoffen besondere Massnahmen zur Eingrenzung von Emissionen. Die Unzulaenglichkeiten bzw. Erschwernisse koennen im wesentlichen durch den hydraulischen Transport und die hydraulische Einbringung (Spuelversatz) unterbunden werden. Einen weiteren Vorteil bietet die Hydromechanisation, wenn ein Stoffgemisch zum Einsatz kommt (Staeube aus der Muellverbrennung - Traegerfluessigkeit - und Bindemittel), welches nach der Ablagerung die Fluessigkeit bindet und so den Hohlraum kompressionsfrei vollstaendig ausfuellt. Ein tragfaehiges Fundament fuer das Dickstoffverfahren kann somit nur durch eine tiefgehende Analyse der anfallenden Stoffe aus der Rauchgasreinigung geschaffen werden. Dem diente das nunmehr bearbeitete Projekt 'Grundlagenuntersuchungen zum Dickstoffverfahren

  15. Report on the explosion, fire, and oil spill resulting in one fatality and injury on September 21, 1978, at Well 6 of Cavern 6 at the West Hackberry, Louisiana, oil storage site of the strategic petroleum reserve. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    1978-11-01

    The following report is the independent product of the Accident Investigation Committee which was commissioned by the Department of Energy following the accident on September 21, 1978, at the Strategic Petroleum Reserve site at West Hackberry, Louisiana. This Committee is charged with the task of determining the nature, extent, and causes of that accident, which resulted in loss of life, injury and property damage, and the need for corrective action. A nonburning oil spill went into nearby Black Lake, but was contained by the deployment of a series of oil spill containment booms and a prevailing wind from the northeast that kept the oil spill in a restricted area near shore. Because of the rapid and effective containment and cleanup of the oil spill by the Rapid Response Team, it appears very likely at this time that Black Lake will not sustain any permanent environmental damage. Cavern 6 initially contained approximately 7,000,000 barrels of oil at a pressure of 650 psig measured at the well head. As of September 29, 1978, the Strategic Petroleum Reserve Office - New Orleans (SPRO) estimated that oil expulsion from Cavern 6 was 67,510 barrels. Of this, 34,620 barrels of oil are accounted for, including 31,200 barrels of oil released into Black Lake and subsequently recovered. The remainder (32,890 barrels) was assumed by SPRO to have been burned. The total loss is presently estimated by the Accident Investigation Committee 's consultant to be $12 million. An assessment of the technical problems present at the time of the accident is given. Recommendations for improved safety procedures are included.

  16. Glaucoma secundário à fístula carótido-cavernosa espontânea com resolução após a embolização da fístula: relato de caso Secondary glaucoma following carotid cavernous fistula resolved after fistula's embolization: case report

    Directory of Open Access Journals (Sweden)

    Marcelo Jarczun Kac

    2010-08-01

    Full Text Available Fístulas carótido-cavernosas espontâneas são raras e ocorrem mais frequentemente em mulheres de meia-idade. Os autores relatam um caso de uma fístula carótido-cavernosa espontânea em mulher idosa evoluindo com glaucoma de difícil controle. Após a embolização cirúrgica da fístula a paciente apresentou regressão da sintomatologia e normalização da pressão intraocular.Spontaneous carotid cavernous fistulas are a rare entity occurring more frequently in middle aged women. The authors report a case of a spontaneous carotid cavernous fistula in an elderly woman resulting in glaucoma of hard management. After surgical embolization of the fistula, the symptoms regressed and the intraocular pressure moved back to regular levels.

  17. Complex paraclinoidal and giant cavernous aneurysms: importance of preoperative evaluation with temporary balloon occlusion test and SPECT Aneurismas paraclinoideos complexos e cavernosos gigantes: importância da avaliação pré-operatória com teste de oclusão temporária com balão e SPECT

    OpenAIRE

    Antônio Aversa do Souto; Flavio S. Domingues; Gaudencio Espinosa; Eduardo Wajnberg; Haroldo Chagas; Rodrigo Tragante; Marcelo Altino; Charles André; Jorge Marcondes de Souza

    2006-01-01

    In the treatment of complex paraclinoidal and giant cavernous aneurysms, preservation of the patency of the internal carotid artery (ICA) is not always possible, and therapeutic occlusion of the carotid is still an important option for their management. A complete preoperative evaluation of the carotid reserve circulation, including the use of temporary balloon occlusion test and single photon emission computerized tomography (SPECT) should be included in the current paradigms of paraclinoida...

  18. Clinical analysis of postoperative complicated chylous ascites of cavernous transformation of portal vein in children%小儿门静脉海绵样变术后并发乳糜腹水临床分析

    Institute of Scientific and Technical Information of China (English)

    高志刚; 熊启星; 钭金法; 王金湖; 黄寿奖; 钱云忠; 章希圣

    2008-01-01

    Objective To analyze the cause,prevention and therapy of postoperative complicated chylous ascites of cavernous transformation of portal vein in children.Methods Between Jan.2001 and Apr.1 2006.9 patients(male 5,female 4)who had recurrent upper gastrointestinal hemorrhage caused by cavernous degeneration of portal vein were operated and analyzed retrospectively.Their age ranged from 2yr7mon to 12yr2mon with an average of 7yr3mon.Four patients had complicated postoperative chylous ascites.Of them,2 cases were performed on splenectomy and splenorenal shunt,1 was received side-to-side mesocaval shunt and 1 had distal splenorenal shunt.Results Three of the 4 patients were cured after short-term fasting and total parental nutrition(TPN)administrated for 1-4 weeks.One case had accumulating ehylus aboUt 2000 ml daily after 4 weeks of conservative treatment,and the chylus was discharged one week after a peritoneo-saphenous shunt. An patients were followed-up from 1 year to 6 years without recurrence.Conclusions The cause of postoperative complicated chylous ascites of cavernous transformation of portal vein in children is the damaging of lymphatic vessels and the chylocyst during operation.Conservative therapy is effective,whereas an operation is chosen if necessary.%目的 本文探讨小儿门静脉海绵样变术后并发乳糜腹水的发病原因,预防措施及治疗方法.方法 回顾性分析本院5年间收治因门静脉海绵样变门脉高压而反复上消化道出血患儿9例,均行手术治疗,术后4例出现乳糜腹,其中2例发生于脾脏切除加脾肾静脉分流术后,1例发生于肠系膜上静脉下腔静脉分流术后,1例发生于Warren术后.结果 4例乳糜腹水患儿有3例经过禁食及TPN等保守治疗后在术后1~4周乳糜腹水消失,1例患儿经过4周保守治疗后每天仍有2000 ml左右的乳糜腹水,在术后4周行腹腔大隐静脉转流术,术后1周乳糜腹水消失.随访1~6年,均无复发.结论 门静脉

  19. Study on the planning of a demonstration plant for hydrogen fuel production by electrolysis using caching in salt caverns under pressure; Studie ueber die Planung einer Demonstrationsanlage zur Wasserstoff-Kraftstoffgewinnung durch Elektrolyse mit Zwischenspeicherung in Salzkavernen unter Druck

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-02-05

    In a two year research project the long-term storage of hydrogen as energy carrier has been assessed in detail for large renewable electricity quantities in underground storage caverns in Germany. Next to a regions analysis for potential storage sites, the benchmarking against other large scale storage concepts, a comparative and perspective analysis of alkaline and PEM-electrolysers also potential business cases for Power-to-Hydrogen in the mobility sector as well as for the chemical, electricity and natural gas industry have been analysed. [German] Durch den geplanten Ausbau der Stromerzeugung aus fluktuierenden, erneuerbaren Energien in Deutschland ruecken Speichertechnologien fuer elektrische Energie immer staerker in den Fokus des industriellen und politischen Interesses. Eine vielversprechende Moeglichkeit fuer eine Langzeitspeicherung bei hohen Anteilen von Wind- und Photovoltaikanlagen sind Speichertechnologien wie die Wasserstoffspeicherung mit Hilfe von Wasserelektrolyseuren. Diese koennen erneuerbaren Strom in grossen Mengen und bei entsprechender Steuerung selektiv in Zeiten mit hohem Dargebot z.B. an Windstrom chemisch speichern. Der gespeicherte Wasserstoff kann dann entweder zu einem spaeteren Zeitpunkt wieder rueckverstromt oder direkt stofflich verwertet werden, z.B. als Kraftstoff fuer den Verkehrssektor, als chemischer Rohstoff oder fuer den Hausenergiebereich durch Einspeisung in das Erdgastransportnetz. Thema der vorliegenden Studie sind Analysen und Planungen fuer die Erprobung des Gesamtsystems ''Wasserstoff-Elektrolyse-Speicherung'' in energiewirtschaftlich relevanten Dimensionen. Dazu werden mit einem neuen Ansatz techno-oekonomische Entwicklungspfade fuer Wasserstoff-Systeme unterschiedlicher Groesse und Technologien charakterisiert und technologische Risiken bei der Realisierung dieser Systeme identifiziert und bewertet. Diese Arbeiten werden ergaenzt durch Arbeiten auf dem Gebiet der Salzkavernenspeicherung in Form

  20. AB117. Efficacy and mechanism of combination therapy using Icariin and daily sildenafil citrate for the treatment of erectile dysfunction in a rat model of bilateral cavernous nerves injury

    Science.gov (United States)

    Xu, Yongde; Guan, Ruili; Lei, Hongen; Yang, Yong; Xin, Zhongcheng

    2016-01-01

    The commonly utilized phosphodiesterase type 5 (PDE5) inhibitors does not lead to satisfactory penile erection after radical prostatectomy due to lack of nitric oxide (NO) released from the damaged cavernous nerves (CNs). Of particular interest is that Icariin (ICA) has been demonstrated to increase the expression of neuronal NO synthase (nNOS) in our previous work. In this study, the efficacy and mechanisms ICA in combination with daily sildenafil for the treatment of neurogenic erectile dysfunction (ED) was investigated in a rat model of bilateral CNs injury (BCNI). Sixty male Sprague-Dawley rats injected with 5-ethynyl-2-deoxyuridine (EdU; 50 mg/kg) at newborn were used to track endogenous stem cells (SCs). Fourty-eight rats of BCNI were randomized equally into gavage feeding of vehicle, sildenafil, ICA and sildenafil+ICA, respectively. Twelve sham-operated rats received vehicle treatment and served as control. Interestingly, ICA in combination with sildenafil resulted in better erectile function and effectively preserved the penile size compared with the control and sildenafil groups (P<0.05). In addition, the numbers of nNOS-positive nerves and EdU-positive cells coexpressing Schwann cell marker S100 in the ICA-treated groups were greater compared with the control group (P<0.05). These results indicate that ICA promotes endogenous SCs to differentiate into Schwann cells, which is essential for the regeneration of nNOS-positive nerves after BCNI; on this basis, sildenafil can then improve penile engorgement through the NO-activated smooth muscle relaxation. Therefore, the combined use of ICA and daily sildenafil may be a candidate for the treatment of neurogenic ED in the future.