WorldWideScience

Sample records for caverns

  1. CMS cavern inspection robot

    CERN Document Server

    Ibrahim, Ibrahim

    2017-01-01

    Robots which are immune to the CMS cavern environment, wirelessly controlled: -One actuated by smart materials (Ionic Polymer-Metal Composites and Macro Fiber Composites) -One regular brushed DC rover -One servo-driven rover -Stair-climbing robot

  2. Brainstem Cavernous Angioma

    Science.gov (United States)

    ... surgical resection of cavernous angiomas, as they provide functional drainage. [5] Elimination of these anomalies can result ... from the brainstem; however, the potential for significant functional deficits from surgical complications is still significant. This ...

  3. The CMS experimental cavern

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    These images taken in early September 2005 show the cathedral-like cavern into which the CMS experiment will be installed. The 26X26X60 cubic metre hall is the largest underground cavern at CERN, located under the town of Cessy in France. Weighing 12 500 tonnes, the huge CMS detector will be assembled in a specially constructed hall above ground before being lowered into the experimental hall ready for the LHC start-up in 2008.

  4. Cerebral Cavernous Malformation and Hemorrhage

    Science.gov (United States)

    ... Text Size: SMALL • LARGE Cerebral Cavernous Angioma and Hemorrhage By Jack Hoch; Reviewed by Dr. Issam Awad ... for years, the mechanism by which these lesions hemorrhage remains poorly understood. Hemorrhage Types Since cavernous angiomas ...

  5. Study of mined storage caverns

    International Nuclear Information System (INIS)

    1975-06-01

    All available information concerning 75 mined storage caverns as well as the investigative techniques utilized to determine the feasibility of a cavern site is presented. Potential new storage caverns may be for products such as high or low vapor pressure petroleum products, other chemical products, aid industrial or nuclear waste

  6. Penile cavernous hemangioma

    Directory of Open Access Journals (Sweden)

    Abdelmoughit ECHCHAOUI

    2015-06-01

    Full Text Available Hemangiomas are benign lesions that occur in any part of the body in newborns or in young patients, they are typically capillary or cavernous. Cavernous hemangioma of the penis is extremely rare; and its etiology is not completely understood. Treatment options (surgical excision, laser therapy or sclerotherapy… are controversial and are required if pain, cosmetic defect and/or bleeding during intercourse.                                                  We report a case of a 26 years old man presented with a five years history of a painless lesion on his penis. Physical examination showed an ovoid, solid, 1 x 2 mm in size on the dorsum of penis (Panel A and two elevated irregular lesions on the ventral side (Panel B. The lesions were compressive, nonpulsatile and bluish-red in color with strawberry like appearance. Biopsy and histopathological examination of the lesion revealed a gaping and communicating vessels proliferated in the superficial and medium dermis which is pathognomonic for cavernous hemangioma (Panel C and D. Given the small size, the large number of the lesions, the young age, and the ulceration risk during intercourse if skin graft after excision, Neodymium: YAG laser coagulation was recommended to get a good cosmetic results and sexual function satisfaction.

  7. Ceremony for ATLAS cavern

    CERN Multimedia

    2003-01-01

    Wednesday 4 June will be a special day for CERN. The President of the Swiss Confederation, Pascal Couchepin, will officially inaugurate the huge ATLAS cavern now that the civil engineering works have ended. The inauguration ceremony will be held in the ATLAS surface building, with speeches by Pascal Couchepin and CERN, ATLAS and civil engineering personalities. This ceremony will be Webcast live. To access the Webcast on 4 June at 18h00 go to CERN Intranet home page or the following address : http://webcast.cern.ch/live.php

  8. The huge ATLAS cavern now fully excavated

    CERN Multimedia

    2002-01-01

    Excavation of the ATLAS cavern is now complete! At the end of two years' work involving a tremendous technical challenge, the civil engineering contractors have succeeded in digging out one of the biggest experimental caverns in the world. Bravo!

  9. Digging the CMS experimental cavern

    CERN Multimedia

    Laurent Guiraud

    2001-01-01

    The huge CMS experimental cavern is located 100 m underground and has two access shafts through which the experiment's components will be lowered. Initially assembled on the surface, each part of the 12 500 tonne machine must be lowered individually with very little clearance.

  10. Civil engineering in the ATLAS cavern

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    Work continues in the cathedral-like cavern that will soon contain ATLAS, the largest particle detector of its type in the world. For such a huge detector, an equally giant cavern must be excavated 100 m underground. The roof must be held without any normal rests at the base; instead it will be supported by huge anchors embedded in concrete that will stop the roof from caving in, located in galleries above the cavern.

  11. Reinforcement of the concrete base slab of the ATLAS cavern

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    Photo 02: UX15 cavern, preparation for concreting of base slab first lift. Photo 05: UX15 cavern, placing of reinforcement for base slab first lift. Photo 07: UX15 cavern, preparation for concreting of base slab first lift. Photo 09: UX15 cavern, placing of reinforcement for base slab first lift. Photo 10: UX15 cavern, view into PX14 shaft above. Photo 12: UX15 cavern, temporary access platform of RB16 tunnel. Photo 15: UJ17 chamber, invert excavation.

  12. A 12-year cavern abandonment test

    Directory of Open Access Journals (Sweden)

    Brouard B.

    2010-06-01

    Full Text Available In 1997-1998, an abandonment test was performed in a 950-m deep, 8000-m3 salt cavern operated by GDF SUEZ at Etrez, France. In this relatively small brine-filled cavern, which had been kept idle for 15 years before the test, thermal equilibrium was reached. A special system was designed to monitor leaks, which proved to be exceedingly small. In these conditions, brine permeation and cavern creep closure are the only factors to play significant roles in pressure evolution. This test strongly suggested that obtaining an equilibrium pressure such that the effects of these two factors were exactly equal would be reached in the long term. Four years later, pressure monitoring in the closed cavern resumed. Pressure evolution during the 2002-2009 period confirmed that cavern brine pressure will remain constant and significantly smaller than geostatic pressure in the long term, precluding any risk of fracturing and brine seepage to the overburden layers.

  13. Rock cavern storage of spent fuel

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Won Jin; Kim, Kyung Soo [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kwon, Sang Ki [Inha University, Incheon (Korea, Republic of)

    2015-12-15

    The rock cavern storage for spent fuel has been assessed to apply in Korea with reviewing the state of the art of the technologies for surface storage and rock cavern storage of spent fuel. The technical feasibility and economic aspects of the rock cavern storage of spent fuel were also analyzed. A considerable area of flat land isolated from the exterior are needed to meet the requirement for the site of the surface storage facilities. It may, however, not be easy to secure such areas in the mountainous region of Korea. Instead, the spent fuel storage facilities constructed in the rock cavern moderate their demands for the suitable site. As a result, the rock cavern storage is a promising alternative for the storage of spent fuel in the aspect of natural and social environments. The rock cavern storage of spent fuel has several advantages compared with the surface storage, and there is no significant difference on the viewpoint of economy between the two alternatives. In addition, no great technical difficulties are present to apply the rock cavern storage technologies to the storage of domestic spent fuel.

  14. Digging a cavern for a titan

    CERN Multimedia

    Patrice Loiez

    1999-01-01

    Civil engineers work 100 m underground near the France-Swiss border on the cavern that will soon house ATLAS, one of the experiments on CERN's new LHC accelerator. All personnel and equipment must be lowered by crane down the access shaft. When completed this cavern will have one of the largest spans constructed at 35 m, which required the roof to be supported by large steel anchors buried in concrete.

  15. End of construction of the CMS cavern

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    View of the CMS cavern with its impressive dimensions: 53 m long, 27 m wide and 24 m high. The construction of this underground complex has been a spectacular feat of engineering. This second of the new caverns for the LHC experiments is the result of six-and-a-half years of work, and its completion marks the end of the large-scale engineering work for the LHC.

  16. Analysis of cavern stability at the West Hackberry SPR site.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L.; Sobolik, Steven Ronald

    2009-05-01

    This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve (SPR) West Hackberry site. The cavern field comprises 22 caverns. Five caverns (6, 7, 8, 9, 11) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 17 caverns (101-117) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a three-dimensional geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios corresponding to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant results in this report are relevant to Cavern 6. The cavern is shaped like a bowl with a large ceiling span and is in close proximity to Cavern 9. The analyses predict tensile stresses at the edge of the ceiling during repressuization of Cavern 6 following workover conditions. During a workover the cavern is at low pressure to service a well. The wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension around the edge of the large ceiling span. With time, these stresses relax to a compressive state because of salt creep. However, the potential for salt fracture and propagation exists, particularly towards Cavern 9. With only 200 ft of salt between the caverns, the operational consequences must be examined if the two caverns become connected. A critical time may be during a workover of Cavern 9 in part because of the operational vulnerabilities, but also because dilatant damage is

  17. The imaging of conditions affecting the cavernous sinus

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Y., E-mail: yenzhitang@doctors.net.u [Royal Free Hospital, Pond Street London NW32QG (United Kingdom); Booth, T.; Steward, M.; Solbach, T.; Wilhelm, T. [Royal Free Hospital, Pond Street London NW32QG (United Kingdom)

    2010-11-15

    The cavernous sinus can be affected by a wide range of conditions including tumours, infection, inflammation, and trauma. Disease in the cavernous sinus can produce characteristic signs and symptoms, which relate to the numerous crucial structures traversing and surrounding the cavernous sinus. Imaging, with the use of different techniques, plays a crucial role in diagnosis and management. The anatomy and imaging of the different disease entities in the cavernous sinus will be reviewed.

  18. Cavernous transformation of the portal vein

    International Nuclear Information System (INIS)

    Lehotska, V.; Dostalova, K.; Durkovsky, A.; Samal, V.

    1995-01-01

    In this contribution, the authors give an account of a rare case of a cavernous transformation of the portal vein that may have originated secondarily in a proliferative hematogenous disease with a polyglobulia and thrombosis in the periferal blood count as well as development of portal hypertension of a prehepatal type. The state of hyper-coagulation in a myeloproliferative disease may have lead to a chronic thrombosis of the portal vein with a subsequent malformation of the portal vein in terms of a cavernous transformation of the portal vein. The case is an interesting one because of the discrepancy between the gravity of the thrombotic complication and slightness of the symptoms in the clinical picture. The authors point out the importance of ultrasonography and computed tomography examination following the intravenous application of a water solution of a contrast medium in a morphologic diagnosing of a rare complication of a chronic thrombotic clot of the portal vein - the cavernous transformation. (authors)

  19. Analysis of cavern stability at the Bryan Mound SPR site.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L.; Sobolik, Steven Ronald

    2009-04-01

    This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve Bryan Mound site. The cavern field comprises 20 caverns. Five caverns (1, 2, 4, and 5; 3 was later plugged and abandoned) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 16 caverns (101-116) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a 3-D geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios due to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant result in this report is relevant to caverns 1, 2, and 5. The caverns have non-cylindrical shapes and have potential regions where the surrounding salt may be damaged during workover procedures. During a workover the normal cavern operating pressure is lowered to service a well. At this point the wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension and large deviatoric stresses at several locations. With time, these stresses relax to a compressive state due to salt creep. However, the potential for salt damage and fracturing exists. The analyses predict tensile stresses at locations with sharp-edges in the wall geometry, or in the case of cavern 5, in the neck region between the upper and lower lobes of the cavern. The effects do not appear to be large-scale, however, so the only major impact is the potential for stress-induced salt falls in cavern 5, potentially leading to

  20. Systematic Evaluation of Salt Cavern Well Integrity

    Science.gov (United States)

    Roberts, B. L.; Lord, D. L.; Lord, A. S.; Bettin, G.; Sobolik, S. R.; Park, B. Y.

    2017-12-01

    The U.S. Strategic Petroleum Reserve (SPR) holds a reserve of crude oil ( 700 million barrels) to help ease any interruptions in oil import to the United States. The oil is stored in a set of 63 underground caverns distributed across four sites along the U.S. Gulf Coast. The caverns were solution mined into salt domes at each of the four sites. The plastic nature of the salt is beneficial for the storage of crude oil as it heals any fractures that may occur in the salt. The SPR is responsible for operating and maintaining the nearly 120 wells used to access the storage caverns over operational lifetimes spanning decades. Salt creep can induce deformation of the well casing which must be remediated to insure cavern and well integrity. This is particularly true at the interface between the plastic salt and the rigid caprock. The Department of Energy, the SPR Management and Operations contractor, and Sandia National Laboratories has developed a multidimensional well-grading system for the salt cavern access wells. This system is designed to assign numeric grades to each well indicating its risk of losing integrity and remediation priority. The system consists of several main components which themselves may consist of sub-components. The main components consider such things as salt cavern pressure history, results from geomechanical simulations modeling salt deformation, and measurements of well casing deformation due to salt creep. In addition, the geology of the salt domes and their overlying caprock is also included in the grading. These multiple factors are combined into summary values giving the monitoring and remediation priority for each well. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology and Engineering Solutions of Sandia LLC, a wholly owned subsidiary of Honeywell International Inc. for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-NA0003525.

  1. Cavernous haemangioma mimicking as clitoral hypertrophy

    Directory of Open Access Journals (Sweden)

    Sajid Nayyar

    2014-01-01

    Full Text Available Haemangioma is the most common benign neoplasm of infantile age. It is most commonly located in head and neck region, trunk and extremities but very rarely it can be located at clitoris. However, it is very important to differentiate clitoral haemangioma from enlargement of the clitoris secondary to androgen excess. Only four cases of clitoromegaly caused by cavernous haemangioma have been reported in the literature so far. Herein, we report our experience with a 10-year-old girl who presented with clitoromegaly and normal hormonal assay that turned out to be clitoral cavernous haemangioma after histopathological examination of the clitoral mass.

  2. Analysis of cavern shapes for the strategic petroleum reserve.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L.; Sobolik, Steven Ronald

    2006-07-01

    This report presents computational analyses to determine the structural integrity of different salt cavern shapes. Three characteristic shapes for increasing cavern volumes are evaluated and compared to the baseline shape of a cylindrical cavern. Caverns with enlarged tops, bottoms, and mid-sections are modeled. The results address pillar to diameter ratios of some existing caverns in the system and will represent the final shape of other caverns if they are repeatedly drawn down. This deliverable is performed in support of the U.S. Strategic Petroleum Reserve. Several three-dimensional models using a close-packed arrangement of 19 caverns have been built and analyzed using a simplified symmetry involving a 30-degree wedge portion of the model. This approach has been used previously for West Hackberry (Ehgartner and Sobolik, 2002) and Big Hill (Park et al., 2005) analyses. A stratigraphy based on the Big Hill site has been incorporated into the model. The caverns are modeled without wells and casing to simplify the calculations. These calculations have been made using the power law creep model. The four cavern shapes were evaluated at several different cavern radii against four design factors. These factors included the dilatant damage safety factor in salt, the cavern volume closure, axial well strain in the caprock, and surface subsidence. The relative performance of each of the cavern shapes varies for the different design factors, although it is apparent that the enlarged bottom design provides the worst overall performance. The results of the calculations are put in the context of the history of cavern analyses assuming cylindrical caverns, and how these results affect previous understanding of cavern behavior in a salt dome.

  3. Imaging diagnosis of dural and direct cavernous carotid fistulae

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Daniela dos; Monsignore, Lucas Moretti; Nakiri, Guilherme Seizem; Cruz, Antonio Augusto Velasco e; Colli, Benedicto Oscar; Abud, Daniel Giansante, E-mail: danisantos2404@gmail.com [Universidade de Sao Paulo (HCFMRP/USP), Ribeirao Preto, SP (Brazil). Faculdade de Medicina. Hospital das Clinicas

    2014-07-15

    Arteriovenous fistulae of the cavernous sinus are rare and difficult to diagnose. They are classified into dural cavernous sinus fistulae or direct carotid-cavernous fistulae. Despite the similarity of symptoms between both types, a precise diagnosis is essential since the treatment is specific for each type of fistula. Imaging findings are remarkably similar in both dural cavernous sinus fistulae and carotid-cavernous fistulae, but it is possible to differentiate one type from the other. Amongst the available imaging methods (Doppler ultrasonography, computed tomography, magnetic resonance imaging and digital subtraction angiography), angiography is considered the gold standard for the diagnosis and classification of cavernous sinus arteriovenous fistulae. The present essay is aimed at didactically presenting the classification and imaging findings of cavernous sinus arteriovenous fistulae. (author)

  4. Historical Cavern Floor Rise for All SPR Sites

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, Dylan Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-09-01

    The Strategic Petroleum Reserve (SPR) contains the largest supply is the largest stockpile of government-owned emergency crude oil in the world. The oil is stored in multiple salt caverns spread over four sites in Louisiana and Texas. Cavern infrastructure near the bottom of the cavern can be damaged from vertical floor movement. This report presents a comprehensive history of floor movements in each cavern. Most of the cavern floor rise rates ranged from 0.5-3.5 ft/yr, however, there were several caverns with much higher rise rates. BH103, BM106, and BH105 had the three highest rise rates. Information from this report will be used to better predict future vertical floor movements and optimally place cavern infrastructure. The reasons for floor rise are not entirely understood and should be investigated.

  5. Enlargement of Cavernous Haemangioma Associated with ...

    African Journals Online (AJOL)

    1974-04-06

    Apr 6, 1974 ... SUMMARY. A cavernous haemangioma of the liver which enlarged rapidly while the patient was receiving exogenous oestro- gens is reported. A dramatic decrease in the size of the tumour was produced by Iigating the right hepatic artery and portal vein. The literature on large haemangiomas of the liver is.

  6. [Cavernous hemangioma of the liver (author's transl)].

    Science.gov (United States)

    Lanuza, A; Olagüe, R; Vallcanera, A; Gracía, A; Páramo, C; Villanueva, A

    1978-02-01

    A three-month old asymptomatic infant was incidentally found to have an abdominal mass. Through standard radiological and vascular procedures it was defined as being of hepatic origin, vascular etiology and of benign prognosis. Differences among cavernous hemangioma, hepatoma, metastasis and hemangio-endothelioma are summarized. The importance of angiography is emphasized as an essential procedure previous to the surgical evaluation and therapy.

  7. Special people visit the ATLAS cavern

    CERN Multimedia

    Muriel

    ATLAS has been host to many important visitors lately. Here are a selected few: Professor Stephen Hawking visits the ATLAS cavern On Tuesday 26 September 2006 the ATLAS Collaboration was honoured by a very special visit to the detector in the underground cavern. We were pleased to guide Professor Stephen Hawking, the famous cosmologist holding the post of Lucasian Professor of Mathematics at Cambridge University (position held by Isaac Newton in the 17th century), on a tour of the ATLAS pit and the LHC tunnel. The visit was accompanied by a few colleagues from the CERN Theory group, and was only possible thanks to the professional assistance of Olga Beltramello and Bernard Lebegue, who had also taken care of all the necessary preparatory work in the cavern. Professor Hawking was very keen to check for himself the status of the detector installation, and he admired, in particular, the spectacular TGC big wheel on side C. (left) Stephen Hawking in the ATLAS cavern side-C (right) and in the LHC tunnel...

  8. The ATLAS cavern in the spotlight

    CERN Document Server

    On Wednesday, 4th June, the President of the Swiss Confederation, Pascal Couchepin, inaugurated the world's largest experimental cavern, which is to house the ATLAS detector in 2007, and announced Switzerland's gift to CERN of the "Palais de l'Equilibre".

  9. Vascular permeability in cerebral cavernous malformations

    DEFF Research Database (Denmark)

    Mikati, Abdul G; Khanna, Omaditya; Zhang, Lingjiao

    2015-01-01

    Patients with the familial form of cerebral cavernous malformations (CCMs) are haploinsufficient for the CCM1, CCM2, or CCM3 gene. Loss of corresponding CCM proteins increases RhoA kinase-mediated endothelial permeability in vitro, and in mouse brains in vivo. A prospective case-controlled observ...

  10. Subdural hematoma from a cavernous malformation.

    Science.gov (United States)

    Schmitt, Anne J; Mitha, Alim P; Germain, Rasha; Eschbacher, Jennifer; Spetzler, Robert F

    2014-01-01

    To present a case of a cavernous malformation presenting with a subdural hematoma. A 27-year-old woman was admitted with progressively worsening headache, vomiting, weakness, and word-finding difficulties 1 week after she was discharged from an outside hospital, where she was managed conservatively for a presumed traumatic subdural hematoma. Computed tomography revealed an enlarging subacute left hemispheric subdural hematoma for which she underwent drill craniostomy. Postprocedural magnetic resonance imaging showed a posterior left temporal lobe mass consistent with a cavernous malformation juxtaposed with the subdural hematoma. Craniotomy for resection of the lesion was performed. She had an uncomplicated postoperative course and experienced a good recovery. The signs and symptoms, diagnostic imaging, and intraoperative findings suggest that the subdural hematoma was caused by extralesional hemorrhage of the cavernous malformation, which is a rare finding associated with these malformations. The clinical course, radiologic, and intraoperative findings suggest that the subdural hemorrhage was caused by extralesional hemorrhage of the cavernous malformation. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Cavernous sinus syndrome: need for early diagnosis.

    Science.gov (United States)

    Toro, Jaime; Burbano, Lisseth Estefania; Reyes, Saúl; Barreras, Paula

    2015-03-27

    Cavernous sinus syndrome (CSS) is a rare condition characterised by ophthalmoplegia, proptosis, ocular and conjunctival congestion, trigeminal sensory loss and Horner's syndrome. These signs and symptoms result from the involvement of the cranial nerves passing through the cavernous sinus. We report the case of a 53-year-old man with a history of daily stabbing headache associated with dizziness, progressive blurred vision, right ocular pain, ptosis and ophthalmoplegia. After working up the patient, a meningioma was identified as the cause of the CSS. Despite advances in neuroimaging techniques, in some cases, the aetiology of CSS remains difficult to determine. We highlight the clinical and radiological features of a meningioma, one of the causes of CSS. Early diagnosis and treatment of CSS play a key role in a better prognosis. 2015 BMJ Publishing Group Ltd.

  12. Cavernous angioma associated with ipsilateral hippocampal sclerosis

    International Nuclear Information System (INIS)

    Okujava, M.; Ebner, A.; Schmitt, J.; Woermann, F.G.

    2002-01-01

    We report two cases with extratemporal cavernous angioma (CA) and coexisting ipsilateral hippocampal sclerosis. Classically dual pathology is defined as the association of hippocampal sclerosis with an extrahippocampal lesion. Subtle changes in hippocampus might be overlooked in the presence of an unequivocal extrahippocampal abnormality. Seizure outcome after epilepsy surgery in cases with dual pathology is less favourable if only one of the lesions is removed. Dual pathology must always be considered in diagnostic imaging of patients with intractable epilepsy and CA. (orig.)

  13. Necrotizing Fasciitis of the Nose Complicated with Cavernous Sinus Thrombosis

    Directory of Open Access Journals (Sweden)

    D. Swaminath

    2014-01-01

    Full Text Available Necrotizing fasciitis is a rapidly progressive life threatening bacterial infection of the skin, the subcutaneous tissue, and the fascia. We present a case of necrotizing fasciitis involving the nose complicated by cavernous sinus thrombosis. Few cases of septic cavernous sinus thrombosis have been reported to be caused by cellulitis of the face but necrotizing fasciitis of the nose is rare. It is very important to recognize the early signs of cavernous thrombosis. Treatment for septic cavernous sinus thrombosis is controversial but early use of empirical antibiotics is imperative.

  14. Multiple intracranial cavernous angiomas: A rare case series

    Directory of Open Access Journals (Sweden)

    Pradeepgoud H Patil

    2012-01-01

    Full Text Available Cavernous angiomas are cerebral cavernous malformations and they are relatively rare lesions. Two forms of cavernous angiomas have been described: a sporadic form, in which patients usually have a single lesion, and a familial form, the hallmarks of which are multiple lesions and autosomal dominant transmission. The familial form appears to be very uncommon and has mainly been described in the Hispanic population. We report two cases of multiple intracranial cavernous angiomas which is an autosomal dominant pattern of inheritance. It is very rare to find this in non Hispanic population.

  15. Recovery of opthalmoplegia associated with cavernous sinus dural arteriovenous fistulas after transvenous cavernous sinus packing

    International Nuclear Information System (INIS)

    Lv Xianli; Jiang Chuhan; Li Youxiang; Yang Xinjian; Wu Zhongxue

    2010-01-01

    Background: We report the recovery of ophthalmoplegia in 11 patients with cavernous sinus dural arteriovenous fistula (CSDAVF) after sinus packing at follow-up. Methods: Of 18 patients with CSDAVF treated with transvenous cavernous sinus packing between August 2002 and December 2007 at Beijing Tiantan Hospital, there were 9 patients with initial CNIII or CNVI dysfunction and 2 patients with CNVI dysfunction immediately after cavernous sinus packing selected and reevaluated. Results: Of 11 patients with CNIII or CNVI palsy, recovery was complete in 10. In 1 patient, complete CNVI palsy was unchanged because the CSDAVF was not cured. There were 6 men and 5 women with a mean age of 52.9 years. In 5 patients, CNVI palsy was associated with chemosis, proptosis and pulsatile tinnitus. Timing of treatment after onset of symptoms was from 4 to 35 days in 9 patients. All CSDAVFs were Barrow type D. Mean follow-up after treatment was 17.7 months (range, 2-54 months). Conclusion: CSDAVF-induced CNIII or CNVI palsies can be cured after cavernous sinus packing transvenously in most patients.

  16. Recovery of opthalmoplegia associated with cavernous sinus dural arteriovenous fistulas after transvenous cavernous sinus packing

    Energy Technology Data Exchange (ETDEWEB)

    Lv Xianli; Jiang Chuhan; Li Youxiang; Yang Xinjian [Beijing Neurosurgical institute, Beijing Tiantan Hospital, Capital Medical University, 6, Tiantan Xili, Chongwen, Beijing (China); Wu Zhongxue, E-mail: ttyyzjb@sina.co [Beijing Neurosurgical institute, Beijing Tiantan Hospital, Capital Medical University, 6, Tiantan Xili, Chongwen, Beijing (China)

    2010-08-15

    Background: We report the recovery of ophthalmoplegia in 11 patients with cavernous sinus dural arteriovenous fistula (CSDAVF) after sinus packing at follow-up. Methods: Of 18 patients with CSDAVF treated with transvenous cavernous sinus packing between August 2002 and December 2007 at Beijing Tiantan Hospital, there were 9 patients with initial CNIII or CNVI dysfunction and 2 patients with CNVI dysfunction immediately after cavernous sinus packing selected and reevaluated. Results: Of 11 patients with CNIII or CNVI palsy, recovery was complete in 10. In 1 patient, complete CNVI palsy was unchanged because the CSDAVF was not cured. There were 6 men and 5 women with a mean age of 52.9 years. In 5 patients, CNVI palsy was associated with chemosis, proptosis and pulsatile tinnitus. Timing of treatment after onset of symptoms was from 4 to 35 days in 9 patients. All CSDAVFs were Barrow type D. Mean follow-up after treatment was 17.7 months (range, 2-54 months). Conclusion: CSDAVF-induced CNIII or CNVI palsies can be cured after cavernous sinus packing transvenously in most patients.

  17. 36 CFR 7.47 - Carlsbad Caverns National Park.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Carlsbad Caverns National Park. 7.47 Section 7.47 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.47 Carlsbad Caverns National Park. (a...

  18. Intramedullary Cavernous Haemangioma Of Spinal Cord: A case ...

    African Journals Online (AJOL)

    user

    Intramedulary Cavernous Haemangioma Of Spinal Cord. Tadios Muni, Hagos Biluts. East and Central African Journal of Surgery Volume 9 Number 2 - December 2004. 56. Intramedullary Cavernous Haemangioma Of Spinal Cord: A case report and Literature. Review. 1Tadios Muni M.D, 2Hagos Biluts M.D.. 1Senior ...

  19. Convergence models for cylindrical caverns and the resulting ground subsidence

    Energy Technology Data Exchange (ETDEWEB)

    Haupt, W.; Sroka, A.; Schober, F.

    1983-02-01

    The authors studied the effects of different convergence characteristics on surface soil response for the case of narrow, cylindrical caverns. Maximum ground subsidence - a parameter of major importance in this type of cavern - was calculated for different convergence models. The models were established without considering the laws of rock mechanics and rheology. As a result, two limiting convergence models were obtained that describe an interval of expectation into which all other models fit. This means that ground movements over cylindrical caverns can be calculated ''on the safe side'', correlating the trough resulting on the surface with the convergence characterisitcs of the cavern. Among other applications, the method thus permits monitoring of caverns.

  20. Beta adrenergic receptors in human cavernous tissue

    Energy Technology Data Exchange (ETDEWEB)

    Dhabuwala, C.B.; Ramakrishna, C.V.; Anderson, G.F.

    1985-04-01

    Beta adrenergic receptor binding was performed with /sup 125/I iodocyanopindolol on human cavernous tissue membrane fractions from normal tissue and transsexual procedures obtained postoperatively, as well as from postmortem sources. Isotherm binding studies on normal fresh tissues indicated that the receptor density was 9.1 fmoles/mg. with a KD of 23 pM. Tissue stored at room temperature for 4 to 6 hours, then at 4C in saline solution for 19 to 20 hours before freezing showed no significant changes in receptor density or affinity, and provided evidence for the stability of postmortem tissue obtained within the same time period. Beta receptor density of 2 cavernous preparations from transsexual procedures was not significantly different from normal control tissues, and showed that high concentrations of estrogen received by these patients had no effect on beta adrenergic receptor density. Displacement of /sup 125/iodocyanopindolol by 5 beta adrenergic agents demonstrated that 1-propranolol had the greatest affinity followed by ICI 118,551, zinterol, metoprolol and practolol. When the results of these displacement studies were subjected to Scatfit, non- linear regression line analysis, a single binding site was described. Based on the relative potency of the selective beta adrenergic agents it appears that these receptors were of the beta 2 subtype.

  1. Strategic petroleum reserve caverns casing damage update 1997

    Energy Technology Data Exchange (ETDEWEB)

    Munson, D.E.; Molecke, M.A.; Neal, J.T. [and others

    1998-01-01

    Hanging casing strings are used for oil and brine transfer in the domal salt storage caverns of the Strategic Petroleum Reserve (SPR). Damage to these casings is of concern because hanging string replacement is costly and because of implications on cavern stability. Although the causes of casing damage are not always well defined, many events leading to damage are assumed to be the result of salt falls impacting the hanging strings. However, in some cases, operational aspects may be suspected. The history of damage to hanging strings is updated in this study to include the most recent events. Potential general domal and local operational and material factors that could influence the tendency for caverns to have salt falls are examined in detail. As a result of this examination, general factors, such as salt dome anomalies and crude type, and most of the operational factors, such as geometry, location and depressurizations, are not believed to be primary causes of casing damage. Further analysis is presented of the accumulation of insolubles during cavern solutioning and accumulation of salt fall material on the cavern floor. Inaccuracies in sump geometry probably make relative cavern insolubles contents uncertain. However, determination of the salt fall accumulations, which are more accurate, suggest that the caverns with the largest salt fall accumulations show the greatest number of hanging string events. There is good correlation between the accumulation rate and the number of events when the event numbers are corrected to an equivalent number for a single hanging string in a quiescent, operating cavern. The principal factor that determines the propensity for a cavern to exhibit this behavior is thought to be the effect of impurity content on the fracture behavior of salt.

  2. Earthquake resistance of cavern for underground nuclear power plants, (2)

    International Nuclear Information System (INIS)

    Komada, Hiroya

    1983-01-01

    Underground nuclear power plants have been studied as one of new siting forms of the nuclear power plants. This form is that some or all of nuclear power plants would be contained in the caverns within the rock mass. Large underground caverns such as the reactor vessel cavern should be excavated at the construction. Therefore, the study on the stability of such large underground caverns containing big important structure will be very important in case of the design of the underground power plants. However the stability analysis of underground caverns during earthquake has almost never been studied. Consequently the analytical methods have not been established. For the purpose of foreseeing the stability analysis of the large underground caverns during earthquake the dynamic analysis of the underground caverns were studied. The characteristics of the rock mass situated in the coastal hillside suitable to the siting conditions of the underground nuclear power plants in Japan were estimated. The stability during earthquake of the reactor vessel caverns of the tunnel type with the width of 32 m, the height of 46 m and the length of 70 m above which the thickness of earth covering is 100 m were analysed. The dynamic stresses at the surrounding rock mass of the caverns under the horizontal earthquake with 407 gal and the vertical earthquake with 204 gal were calculated. It was obtained from the results that the relaxed zone during earthquake was yielded just at the abutment of the underground in case of both the horizontal earthquake and the vertical earthquake, and the depth of the relaxed zone was 10 m at almost from the arch concrete. It is seemed that such relaxed zone can be treated with rock anchors and arch concretes considering the current reinforcement technique. (author)

  3. Dural fistulas of the cavernous sinus

    International Nuclear Information System (INIS)

    Guibert-Tranier, F.; Piton, J.; Caille, J.M.; Lemoine, J.J.

    1984-01-01

    Five cases of dural fistulas of the cavernous sinus are reported. The clinical aspect of this lesion is often misleading in the absence of subjective or objective bruits. The diagnosis is made at angiography which should systematically include the internal and external carotid arteries bilaterally. The goal of this study was to elucidate the great variability of the venous drainage and to correlate it with the clinical symptoms and course. The main problem is to know when and how these fistulas should be treated. Vascular ligatures should not be performed. Therapeutic angiography is the treatment of choice, but should be limited to the following indications: poorly tolerated bruits, severe ophthalmic damage (elevated ocular tension, diminished visual acuity, or oculomotor paralysis), angiographically demonstrated massive arteriovenous shunting, and a high degree of cortical venous reflux. Whatever the indication, the course after embolisation is rarely predictable and in particular the risk of extensive venous thrombosis or recurrence is great. (orig.)

  4. Cavernous hemangioma of the thoracic spinal cord

    International Nuclear Information System (INIS)

    Wang, A.M.; Lin, J.C.T.; Morris, J.H.; Fischer, E.G.; Petersen, R.

    1988-01-01

    A 25-year-old woman presented with a four-year history of progressive right-lower-extremity weakness and atrophy and a left hemisensory deficit was found. Metrizamide-enhanced spinal CT scan showed an intramedullary lesion at the level of T1-T2; this had expanded the cord in fusiform fashion but showed no evidence of a cystic component. Surgical resection was performed and the pathological diagnosis was cavernous hemangioma. Two and one-half years later, her left hemisensory deficit was worsening and a spinal MRI showed high signal intensity mass in the region of the previous surgery consistent with chronic hematoma which was re-evacuated with some improvement in the patient's neurological condition. (orig.)

  5. [Cavernous haemangiomas: hearing and vestibular inaugural symptoms].

    Science.gov (United States)

    Dumas, G; Schmerber, S

    2004-11-01

    Cavernous haemangiomas (cavernomas)(CH) are relatively rare (2% of cranial tumoral pathology) vascular malformations mostly observed in the central nervous system. Their most common topographical site in brain stem is midline in the pons, for which clinical course may mimic symptoms of peripheral origin (sudden deafness, fluctuating hearing loss, Meniere-like vertigo). To establish the correlation between the clinical manifestations of hearing and balance disturbance and the anatomical site within the pons of cavernous haemangiomas, and to describe their clinical features, and the findings on auditory brainstem response (ABR) and magnetic resonance imaging (MRI). To propose a literature review about CH and its implications. We made a retrospective review of the histories of three patients aged 24, 44 and 45 years, diagnosed as having cavernomas of the brainstem in which audiometric evaluation, videonystagmography (VNG), ABR and imaging techniques lead to the diagnosis of intracranial cavernoma. The clinical and radiological files were reviewed and a direct relationship between symptoms and localization was found in all 3 patients, especially in relation to our understanding of the auditory and vestibular pathways within the brainstem. The literature regarding cavernomas of the pons is reviewed and the clinical, neuroimage, pathological, natural course and management aspects of the disease are discussed. We recommend the use of cerebral MRI for initial diagnosis which shows a typical rosette-like appearance with a heterogeneous signal on T2-weighted images, along with follow-up and investigation into similar profiles among family members. At present there is no consensus about the treatment to follow when cavernomas are located in the brain stem. There is no specific medical treatment for this condition, and surgery is indicated only exceptionally. Anticoagulant therapy, platelet-dispersing medication and violent sports activities are contraindicated.

  6. Therapeutic surprise! Photodynamic therapy for cavernous haemangioma of the disc

    Directory of Open Access Journals (Sweden)

    Mahesh P Shanmugam

    2017-01-01

    Full Text Available Purpose: To report the response of cavernous haemangioma of the disc to PDT. Methods and Patients: A 32 years old lady presented to us with complaints of sudden onset of blurry vision in her right eye. What seemed initially as polypoidal choroidal vasculopathy turned out as cavernous haemangioma of the disc after pneumatic displacement of the sub-retinal haeme. She was treated with PDT as she was prone to recurrent haemorrhage from the lesion due to her low platelet count. Results: Complete regression of the cavernous haemangioma was noted as early as the second week itself and remained regressed for 4 months. Conclusion: PDT can be safe option for patients presenting with symptomatic cavernous haemangioma of the disc or retina.

  7. Cavernous sinus syndrome secondary to intracranial lymphoma in a cat.

    Science.gov (United States)

    Guevar, Julien; Gutierrez-Quintana, Rodrigo; Peplinski, George; Helm, Jenny R; Penderis, Jacques

    2014-06-01

    Cavernous sinus syndrome is characterised by internal and external ophthalmoplegia and sensory deficits over the head due to combined deficits of the three cranial nerves (CNs) responsible for the eye movements and pupil function (CN III, IV, VI) and at least one branch of the trigeminal nerve (CN V). It has rarely been described in cats and may occur secondarily to inflammatory, infectious or neoplastic lesions within the region of the cavernous sinus on the ventral aspect of the calvarium. This report describes the clinical and magnetic resonance imaging findings in a 14-year-old domestic shorthair cat with neurological deficits compatible with cavernous sinus syndrome caused by presumptive extranodal lymphoma. Treatment with chemotherapy resulted in clinical and imaging remission. Identification of the neurological deficits in cavernous sinus syndrome allows accurate neuroanatomical localisation in order to target diagnostic imaging studies. © ISFM and AAFP 2013.

  8. Cavernous sinus subarachnoid diverticulum and sixth nerve palsy

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Tatsuya; Negoro, Makoto; Awaya, Shinobu

    1987-05-01

    Metrizamide CT cisternography in a young woman with a chronic sixth nerve palsy demonstrated a cavernous sinus subarachnoid diverticulum originating from the cerebellopontine cistern. The possible etiologic role of this diverticulum in her palsy is discussed.

  9. Cavernous sinus subarachnoid diverticulum and sixth nerve palsy

    International Nuclear Information System (INIS)

    Kobayashi, Tatsuya; Negoro, Makoto; Awaya, Shinobu

    1987-01-01

    Metrizamide CT cisternography in a young woman with a chronic sixth nerve palsy demonstrated a cavernous sinus subarachnoid diverticulum originating from the cerebellopontine cistern. The possible etiologic role of this diverticulum in her palsy is discussed. (orig.)

  10. ADVANCED UNDERGROUND GAS STORAGE CONCEPTS REFRIGERATED-MINED CAVERN STORAGE

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    Limited demand and high cost has prevented the construction of hard rock caverns in this country for a number of years. The storage of natural gas in mined caverns may prove technically feasible if the geology of the targeted market area is suitable; and economically feasible if the cost and convenience of service is competitive with alternative available storage methods for peak supply requirements. It is believed that mined cavern storage can provide the advantages of high delivery rates and multiple fill-withdrawal cycles in areas where salt cavern storage is not possible. In this research project, PB-KBB merged advanced mining technologies and gas refrigeration techniques to develop conceptual designs and cost estimates to demonstrate the commercialization potential of the storage of refrigerated natural gas in hard rock caverns. Five regions of the U.S.A. were studied for underground storage development and PB-KBB reviewed the literature to determine if the geology of these regions was suitable for siting hard rock storage caverns. Area gas market conditions in these regions were also studied to determine the need for such storage. Based on an analysis of many factors, a possible site was determined to be in Howard and Montgomery Counties, Maryland. The area has compatible geology and a gas industry infrastructure for the nearby market populous of Baltimore and Washington D.C.. As Gas temperature is lowered, the compressibility of the gas reaches an optimum value. The compressibility of the gas, and the resultant gas density, is a function of temperature and pressure. This relationship can be used to commercial advantage by reducing the size of a storage cavern for a given working volume of natural gas. This study looks at this relationship and and the potential for commercialization of the process in a storage application. A conceptual process design, and cavern design were developed for various operating conditions. Potential site locations were considered

  11. Cerebral cavernous malformations. Serial magnetic resonance imaging findings in patients with and without gamma knife surgery

    Energy Technology Data Exchange (ETDEWEB)

    Yoon Pyeong-Ho; Kim, Dong-Ik; Jeon Pyoung; Ryu, Young-Hoon; Hwang, Geum-Joo; Park, Sang-Joon [Yonsei Univ., Seoul (Korea, Republic of). Coll. of Medicine

    1998-10-01

    To classify the cerebral cavernous malformations and to investigate the natural history of cavernous malformations according to the classification, 41 patients with 61 cavernous malformations (40 cavernous malformations from 22 patients treated with gamma knife surgery) were regularly followed up using MR imaging for a mean period of 25.5 months in treated cavernous malformations and 20.7 months in untreated cavernous malformations, respectively. Cavernous malformations were classified into four types. Follow-up MR images were analyzed to evaluate changes in size, signal intensity, rebleeding, and perilesional adverse reaction of irradiation. A total of 61 cavernous malformations including 17 in type I, 23 in type II, 10 in type III, and 11 in type IV showed usual degradation of blood product in 22 cavernous malformations, no change in shape and signal intensity in 31 cavernous malformations, and eight cavernous malformations with rebleedings in the serial MR images. In these eight cavernous malformations with rebleedings, six occurred in type II and two in type III, but none in type I or IV. Rebleedings were more frequent in type II than in other types. Adverse reaction of irradiation was observed in five of 22 patients treated with gamma knife surgery. Although most cerebral cavernous malformations showed evolution of hemorrhage or no change in size or shape on follow-up MR images, cerebral cavernous malformations represented as mixture of subacute and chronic hemorrhage with hemosiderin rim (type II) have a higher frequency to rebleed than other types of cerebral cavernous malformations. Cerebral cavernous malformations represented as hemosiderin deposition without central core (type IV) have a lower tendency to rebleed than other types and do not need any treatment. Most of the adverse reaction of irradiation after gamma knife surgery around cavernous malformations are transient findings and are considered to be perilesional edema. (K.H)

  12. Features of Bayou Choctaw SPR caverns and internal structure of the salt dome.

    Energy Technology Data Exchange (ETDEWEB)

    Munson, Darrell E.

    2007-07-01

    The intent of this study is to examine the internal structure of the Bayou Choctaw salt dome utilizing the information obtained from graphical representations of sonar survey data of the internal cavern surfaces. Many of the Bayou Choctaw caverns have been abandoned. Some existing caverns were purchased by the Strategic Petroleum Reserve (SPR) program and have rather convoluted histories and complex cavern geometries. In fact, these caverns are typically poorly documented and are not particularly constructive to this study. Only two Bayou Choctaw caverns, 101 and 102, which were constructed using well-controlled solutioning methods, are well documented. One of these was constructed by the SPR for their use while the other was constructed and traded for another existing cavern. Consequently, compared to the SPR caverns of the West Hackberry and Big Hill domes, it is more difficult to obtain a general impression of the stratigraphy of the dome. Indeed, caverns of Bayou Choctaw show features significantly different than those encountered in the other two SPR facilities. In the number of abandoned caverns, and some of those existing caverns purchased by the SPR, extremely irregular solutioning has occurred. The two SPR constructed caverns suggest that some sections of the caverns may have undergone very regular solutioning to form uniform cylindrical shapes. Although it is not usually productive to speculate, some suggestions that point to the behavior of the Bayou Choctaw dome are examined. Also the primary differences in the Bayou Choctaw dome and the other SPR domes are noted.

  13. Underground hydrogen storage. Final report. [Salt caverns, excavated caverns, aquifers and depleted fields

    Energy Technology Data Exchange (ETDEWEB)

    Foh, S.; Novil, M.; Rockar, E.; Randolph, P.

    1979-12-01

    The technical and economic feasibility of storing hydrogen in underground storage reservoirs is evaluated. The past and present technology of storing gases, primarily natural gas is reviewed. Four types of reservoirs are examined: salt caverns, excavated caverns, aquifers, and depleted fields. A technical investigation of hydrogen properties reveals that only hydrogen embrittlement places a limit on the underground storage by hydrogen. This constraint will limit reservoir pressures to 1200 psi or less. A model was developed to determine economic feasibility. After making reasonable assumptions that a utility might make in determining whether to proceed with a new storage operation, the model was tested and verified on natural gas storage. A parameteric analysis was made on some of the input parameters of the model to determine the sensitivity of the cost of service to them. Once the model was verified it was used to compute the cost of service of storing hydrogen in the four reservoir types. The costs of service for hydrogen storage ranged from 26 to 150% of the cost of the gas stored. The study concludes that it is now both safe and economic to store hydrogen in underground reservoirs.

  14. Gallium scintigraphy in a case of septic cavernous sinus thrombosis

    International Nuclear Information System (INIS)

    Palestro, C.J.; Malat, J.; Gladstone, A.G.; Richman, A.H.

    1986-01-01

    Septic cavernous sinus thrombosis, a relatively uncommon disease entity, frequently can be fatal. Early diagnosis is imperative in order that appropriate treatment be instituted. A 59-year-old woman who was admitted to our institution with complaints of diplopia, blurred vision and fevers that developed following a tooth extraction is presented. Initial CT and lumbar puncture on the day of admission were totally normal. A repeat CT performed 48 hours after admission, on the same day as gallium imaging, demonstrated findings consistent with cavernous sinus thrombosis. Gallium imaging demonstrated intense uptake in the left cavernous sinus and left orbit as well as moderately increased activity in the right cavernous sinus and orbit, confirming infection. The patient was treated with antibiotics, and repeat CT and gallium imaging were performed ten days later, both of which demonstrated near total resolution of the disease process. Conceivably, if gallium imaging had been initiated on the day of admission it may have been the first study to demonstrate an infectious process in the cavernous sinus. Gallium imaging should be considered as a diagnostic tool in the noninvasive workup of this entity

  15. Surgical Outcomes of Cavernous Sinus Syndrome in Pituitary Adenomas.

    Science.gov (United States)

    Fu, Weilun; Duan, Lian; Geng, Sumin

    2017-11-01

    The type of pituitary adenoma with a manifestation that includes cavernous sinus syndrome is rare. Based on the clinical data of 70 patients, this study investigated the pathogenesis, imaging characteristics, and prognostic factors of pituitary adenoma with cavernous sinus syndrome. We conducted a retrospective analysis of the characteristics of patients with pituitary adenoma with cavernous sinus syndrome who received surgical treatment. The patients were classified into different prognosis groups according to the time required for them to recover from the cavernous sinus syndrome. Univariate analyses were conducted for the correlations between the prognosis and factors. Of the 3598 cases of pituitary adenomas, 70 (1.95%) presented cavernous sinus syndrome. Of the patients, 55.7% recovered within 2 weeks of surgery, 24.3% recovered from 2 weeks to 1 year after surgery, and 20% had not returned to normal after more than 1 year after surgery. Univariate analyses showed that shorter disease duration (P syndrome differs depending on the mechanism of the syndrome. There was no significant difference in the prognosis between patients with total pituitary adenoma resection and subtotal resection. Timely surgery within 100 days of symptom occurrence, Knosp grade 0-2, and associated pituitary apoplexy are predictive factors of good prognosis. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. CAVERN ROOF STABILITY FOR NATURAL GAS STORAGE IN BEDDED SALT

    Energy Technology Data Exchange (ETDEWEB)

    DeVries, Kerry L; Mellegard, Kirby D; Callahan, Gary D; Goodman, William M

    2005-06-01

    This report documents research performed to develop a new stress-based criterion for predicting the onset of damage in salt formations surrounding natural gas storage caverns. Laboratory tests were conducted to investigate the effects of shear stress, mean stress, pore pressure, temperature, and Lode angle on the strength and creep characteristics of salt. The laboratory test data were used in the development of the new criterion. The laboratory results indicate that the strength of salt strongly depends on the mean stress and Lode angle. The strength of the salt does not appear to be sensitive to temperature. Pore pressure effects were not readily apparent until a significant level of damage was induced and the permeability was increased to allow penetration of the liquid permeant. Utilizing the new criterion, numerical simulations were used to estimate the minimum allowable gas pressure for hypothetical storage caverns located in a bedded salt formation. The simulations performed illustrate the influence that cavern roof span, depth, roof salt thickness, shale thickness, and shale stiffness have on the allowable operating pressure range. Interestingly, comparison of predictions using the new criterion with that of a commonly used criterion indicate that lower minimum gas pressures may be allowed for caverns at shallow depths. However, as cavern depth is increased, less conservative estimates for minimum gas pressure were determined by the new criterion.

  17. Burkitt's lymphoma of the skull base presenting as cavernous sinus syndrome in early childhood.

    Science.gov (United States)

    Kalina, P; Black, K; Woldenberg, R

    1996-01-01

    Primary non-Hodgkin's lymphoma of the skull base presenting with neuro-ophthalmologic abnormalities or cavernous sinus involvement is very rare in children. We have found only 13 reported cases of cavernous sinus involvement by lymphoma [1]. We report the case of the youngest child diagnosed with Burkitt's lymphoma of the cavernous sinus and sphenoid sinus, whose first presentation was cavernous sinus syndrome with neuro-ophthalmologic findings.

  18. Two new caverns for LHC experiments ATLAS and CMS

    CERN Document Server

    Rammer, H

    1998-01-01

    The LHC will utilize much of the existing infrastructure already constructed for the LEP. However, to house the new ATLAS and CMS detectors, two huge cavern complexes are required at Point 1 and Point 5 on the LEP. The civil engineering design criteria for the two caverns are presented. Attention is directed to the decisive constraints for the design, such as adverse geological ground conditions, the three-dimensional complexity of the shafts, caverns and tunnels, and the existing LEP structures in the vicinity of the new works which remain operational for the first two years of the project. the paper will demonstrate the different basic requirements of the new underground structures at Point 1 and Point 5. The comparison of the two projects from a civil engineering point of view will aim at explaining why different technical solutions have been adopted for the design and construction of these works.

  19. Giant hepatic cavernous hemangioma. Findings on computed helical tomography

    International Nuclear Information System (INIS)

    Castrillon, German A; Montoya, Maria del Pilar; Soto, Jorge A

    2010-01-01

    Objective: To describe computed helical tomography characteristics of the giant hepatic cavernous hemangioma. Method: During five years, we evaluated 21 patients with 21 giant hepatic cavernous hemangiomas with computed helical and multislice tomography. We included 18 women (86%) and 3 men (14%) with a mean age of 45 years. Results: The mean size of hemangiomas was 10.4 cm. Non enhanced computed tomography Showed 21 hemangiomas with lower density than adjacent hepatic parenchyma , all hemangiomas showed a central cleft area with low density. None hemangioma showed calcifications neither internal septa. In enhanced helical tomography all lesions demonstrated a globular, peripheral enhancing pattern with centripetal filling that begin in the arterial phase and continued in portal and delayed phases. None of the lesions showed complete filling. Conclusion: giant hepatic cavernous hemangiomas showed low attenuation in non enhanced computed tomography. central cleft area was very frequently seen. The enhancement pattern is characteristic, starting at the periphery with centripetal filling but it was never complete.

  20. Cavernous hemangioma of the orbit: an unusual acute presentation

    Science.gov (United States)

    Louisraj, Sophia; Ponnudurai, Thendral; Rodriguez, Dominic; Thomas, Philip A; Nelson Jesudasan, Christadoss Arul

    2017-01-01

    We report an unusual presentation of an orbital cavernous hemangioma in a 26-year-old female, who noted sudden redness and swelling of the left eye (LE) on waking up. At presentation, upper eyelid edema with periorbital ecchymosis and subconjunctival hemorrhage were noted in the LE. Although there was transient symptomatic relief with topical medications, blurring of vision developed in the LE. When seen 10 days later, the patient’s LE showed axial proptosis. Magnetic resonance imaging revealed an intraconal soft tissue mass in the superomedial quadrant of the left orbit. Superior orbitotomy with mass excision was done; histopathological examination of the excised mass revealed a cavernous hemangioma. The patient had complete visual recovery following surgery. To our knowledge, an acute presentation of an orbital cavernous hemangioma with subconjunctival hemorrhage and periorbital ecchymosis has not previously been reported. PMID:28769595

  1. Radiological features of childhood giant cavernous malformations

    Energy Technology Data Exchange (ETDEWEB)

    Ozgen, Burce; Senocak, Efsun; Oguz, Kader K. [Hacettepe University, Department of Radiology, Faculty of Medicine, Ankara (Turkey); Soylemezoglu, Figen [Hacettepe University, Department of Pathology, School of Medicine, Ankara (Turkey); Akalan, Nejat [Hacettepe University, Department of Neurosurgery, School of Medicine, Ankara (Turkey)

    2011-04-15

    Giant cavernous malformations (GCM) are very large, low-flow vascular malformations, which usually have atypical imaging features and are commonly misdiagnosed preoperatively as neoplasms or vascular malformations. These lesions have mostly been reported in children. As cavernomas show different features in children compared to adults, we evaluated the imaging features of pediatric GCMs in order to help in the preoperative diagnosis of these malformations. Brain MR studies of nine children (mean age of 4 years; 8 months-9 years) with biopsy-proven GCM were retrospectively evaluated. We defined GCMs as cavernomas of {>=}4 cm. Lesions were evaluated regarding their size, location, signal characteristics, general appearance (uni/multilocular) as well as regarding the presence of mass effect, edema, and fluid-fluid levels and were classified according to the Mottolese classification of pediatric cavernomas. Lesion locations were parietal (n = 5), frontal (n = 2), temporal, and intraventricular. Seven lesions were in the periventricular region (with five in the periatrial region). Six patients had T1 hyperintense multilobulated lesions with ''bubbles of blood'' appearance and three patients had heterogeneous lesions with reticular core. All lesions had mass effect, edema (marked in four cases), and peripheral hemosiderin rim. Fluid-fluid levels were also common (n = 7). Most of our lesions (six of nine) were classified as type IIIA, two as type IIIC, and one as type IA. In children, a GCM should be considered in case of very large hemorrhagic intra-axial mass with ''bubbles of blood'' multicystic appearance, surrounding hemosiderin ring, fluid-fluid levels, and accompanying edema-mass effect, especially in the periatrial location. (orig.)

  2. NA62 cavern and sub-detectors 2017

    CERN Multimedia

    Graham, Connor

    2017-01-01

    The NA62 cavern, with the completed detector, during breaks in data taking in July 2017. Pictures from 05-07-17 by Dan Protopopescu and pictures from 08-07-17 by Connor Graham (Both Glasgow-affiliated). Includes pictures of the whole experiment, safety systems and sub-detector elements.

  3. Novel Technique for the UX15 Cavern Vault Support System

    CERN Document Server

    Rammer, H

    2000-01-01

    The overall LHC project schedule requires the civil engineering work to begin before the final LEP shutdown. The new caverns for the ATLAS experiment will be built in and around the existing underground structures at point 1. In order to make the best possible use of the time available for the LHC civil engineering before the shutdown of LEP, a particular arrangement for the construction of the UX15 cavern vault has been developed. The basic concept of this arrangement consists of the excavation of the cavern top heading and the installation of the concrete vault immediately afterwards, prior to the subsequent bench excavation after LEP shutdown. A temporary support of the dead weight of the concrete roof will be achieved by the suspension of the roof by 38 no. pre-stressed ground anchors of 225 tons capacity each. This support system will work up to the construction of the cavern base slab and walls and the completion of the permanent concrete lining.

  4. A Case of Brainstem Cavernous Angioma Presenting with Persistent Hiccups

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Arami

    2010-07-01

    Full Text Available "nIntractable hiccup most be considered as a symptom of underlying serious pathologies. We report a case of medulla oblongata cavernous angima presented with persistant hiccup and without any improvement during routine nonpharmacologic and pharmacologic treatment regimns. The patient is under our follow up visits and surgery is very high risk for this young girl.

  5. Simulation of Cavern Formation and Karst Development Using Salt

    Science.gov (United States)

    Kent, Douglas C.; Ross, Alex R.

    1975-01-01

    A salt model was developed as a teaching tool to demonstrate the development of caverns and karst topography. Salt slabs are placed in a watertight box to represent fractured limestone. Erosion resulting from water flow can be photographed in time-lapse sequence or demonstrated in the laboratory. (Author/CP)

  6. Analysis of SPR salt cavern remedial leach program 2013.

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Paula D.; Gutierrez, Karen A.; Lord, David L.; Rudeen, David Keith

    2013-09-01

    The storage caverns of the US Strategic Petroleum Reserve (SPR) exhibit creep behavior resulting in reduction of storage capacity over time. Maintenance of oil storage capacity requires periodic controlled leaching named remedial leach. The 30 MMB sale in summer 2011 provided space available to facilitate leaching operations. The objective of this report is to present the results and analyses of remedial leach activity at the SPR following the 2011 sale until mid-January 2013. This report focuses on caverns BH101, BH104, WH105 and WH106. Three of the four hanging strings were damaged resulting in deviations from normal leach patterns; however, the deviations did not affect the immediate geomechanical stability of the caverns. Significant leaching occurred in the toes of the caverns likely decreasing the number of available drawdowns until P/D ratio criteria are met. SANSMIC shows good agreement with sonar data and reasonably predicted the location and size of the enhanced leaching region resulting from string breakage.

  7. Cavernous hemangioma of the orbit: an unusual acute presentation

    Directory of Open Access Journals (Sweden)

    Louisraj S

    2017-07-01

    Full Text Available Sophia Louisraj,1 Thendral Ponnudurai,1 Dominic Rodriguez,2 Philip A Thomas,1 Christadoss Arul Nelson Jesudasan,1 1Department of Orbit and Oculoplasty, Joseph Eye Hospital, 2Department of Medicine, Kauvery Medical Centre, Tiruchirapalli, India Abstract: We report an unusual presentation of an orbital cavernous hemangioma in a 26-year-old female, who noted sudden redness and swelling of the left eye (LE on waking up. At presentation, upper eyelid edema with periorbital ecchymosis and subconjunctival hemorrhage were noted in the LE. Although there was transient symptomatic relief with topical medications, blurring of vision developed in the LE. When seen 10 days later, the patient’s LE showed axial proptosis. Magnetic resonance imaging revealed an intraconal soft tissue mass in the superomedial quadrant of the left orbit. Superior orbitotomy with mass excision was done; histopathological examination of the excised mass revealed a cavernous hemangioma. The patient had complete visual recovery following surgery. To our knowledge, an acute presentation of an orbital cavernous hemangioma with subconjunctival hemorrhage and periorbital ecchymosis has not previously been reported. Keywords: subconjunctival hemorrhage, ecchymosis, cavernous hemangioma

  8. Soft tissue cavernous haemangioma: Photo essay | Girma | Journal ...

    African Journals Online (AJOL)

    Soft tissue cavernous haemangioma: Photo essay. Edom Girma, Asfaw Atnafu. http://dx.doi.org/10.4314/jemp.v4i1.10614 · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL · News.

  9. Estimating the distribution of salt cavern squeeze using subsidence measurements

    NARCIS (Netherlands)

    Fokker, P.A.; Visser, J.

    2014-01-01

    We report a field study on solution mining of magnesium chloride from bischofite layers in the Netherlands at depths between 1500 and 1850 m. Subsidence that was observed in the area is due to part of the brine production being realized by cavern squeeze; some of which were connccted. Wc used an

  10. Odontogenic infection and pachymeningitis of the cavernous sinus.

    Science.gov (United States)

    Jose, Anson; Nagori, Shakil Ahmed; Bhutia, Ongkila; Roychoudhury, Ajoy

    2014-07-01

    Hypertrophic pachymeningitis is a rare inflammatory process that causes thickening of the dura mater. Most cases are idiopathic, but it can result from many inflammatory and infective conditions. We present a case of pachymeningitis of the cavernous sinus, the aetiology of which may have been dental. Copyright © 2014 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  11. Cavernous carotid aneurysms: To do or not to do?

    Directory of Open Access Journals (Sweden)

    Sudha Menon

    2017-01-01

    Full Text Available Cavernous carotid aneurysms (CCA pose considerable dilemmas in management. It is still unclear as to whether an asymptomatic CCA should be subjected to treatment. Similarly, the ideal management strategy for a symptomatic aneurysm is controversial. We present the case of a 60-year-old female with a giant CCA and discuss the management issues.

  12. Fracture and Healing of Rock Salt Related to Salt Caverns

    International Nuclear Information System (INIS)

    Chan, K.S.; Fossum, A.F.; Munson, D.E.

    1999-01-01

    In recent years, serious investigations of potential extension of the useful life of older caverns or of the use of abandoned caverns for waste disposal have been of interest to the technical community. All of the potential applications depend upon understanding the reamer in which older caverns and sealing systems can fail. Such an understanding will require a more detailed knowledge of the fracture of salt than has been necessary to date. Fortunately, the knowledge of the fracture and healing of salt has made significant advances in the last decade, and is in a position to yield meaningful insights to older cavern behavior. In particular, micromechanical mechanisms of fracture and the concept of a fracture mechanism map have been essential guides, as has the utilization of continuum damage mechanics. The Multimechanism Deformation Coupled Fracture (MDCF) model, which is summarized extensively in this work was developed specifically to treat both the creep and fracture of salt, and was later extended to incorporate the fracture healing process known to occur in rock salt. Fracture in salt is based on the formation and evolution of microfractures, which may take the form of wing tip cracks, either in the body or the boundary of the grain. This type of crack deforms under shear to produce a strain, and furthermore, the opening of the wing cracks produce volume strain or dilatancy. In the presence of a confining pressure, microcrack formation may be suppressed, as is often the case for triaxial compression tests or natural underground stress situations. However, if the confining pressure is insufficient to suppress fracture, then the fractures will evolve with time to give the characteristic tertiary creep response. Two first order kinetics processes, closure of cracks and healing of cracks, control the healing process. Significantly, volume strain produced by microfractures may lead to changes in the permeability of the salt, which can become a major concern in

  13. Instability risk analysis and risk assessment system establishment of underground storage caverns in bedded salt rock

    Science.gov (United States)

    Jing, Wenjun; Zhao, Yan

    2018-02-01

    Stability is an important part of geotechnical engineering research. The operating experiences of underground storage caverns in salt rock all around the world show that the stability of the caverns is the key problem of safe operation. Currently, the combination of theoretical analysis and numerical simulation are the mainly adopts method of reserve stability analysis. This paper introduces the concept of risk into the stability analysis of underground geotechnical structure, and studies the instability of underground storage cavern in salt rock from the perspective of risk analysis. Firstly, the definition and classification of cavern instability risk is proposed, and the damage mechanism is analyzed from the mechanical angle. Then the main stability evaluating indicators of cavern instability risk are proposed, and an evaluation method of cavern instability risk is put forward. Finally, the established cavern instability risk assessment system is applied to the analysis and prediction of cavern instability risk after 30 years of operation in a proposed storage cavern group in the Huai’an salt mine. This research can provide a useful theoretical base for the safe operation and management of underground storage caverns in salt rock.

  14. Sensitivity of storage field performance to geologic and cavern design parameters in salt domes.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L. (Sandia National Laboratories, Albuquerque, NM); Park, Byoung Yoon

    2009-03-01

    A sensitivity study was performed utilizing a three dimensional finite element model to assess allowable cavern field sizes for strategic petroleum reserve salt domes. A potential exists for tensile fracturing and dilatancy damage to salt that can compromise the integrity of a cavern field in situations where high extraction ratios exist. The effects of salt creep rate, depth of salt dome top, dome size, caprock thickness, elastic moduli of caprock and surrounding rock, lateral stress ratio of surrounding rock, cavern size, depth of cavern, and number of caverns are examined numerically. As a result, a correlation table between the parameters and the impact on the performance of storage field was established. In general, slower salt creep rates, deeper depth of salt dome top, larger elastic moduli of caprock and surrounding rock, and a smaller radius of cavern are better for structural performance of the salt dome.

  15. Red blood cell scan in cavernous hemangioma of the larynx

    Energy Technology Data Exchange (ETDEWEB)

    Finkelstein, D.M.; Noyek, A.M.; Kirsh, J.C. (Univ. of Toronto, Ontario (Canada))

    1989-09-01

    Cavernous hemangioma of the larynx is an uncommon, difficult-to-diagnose vascular tumor for which there is no significant imaging literature to date. The possibility of improved diagnosis through RBC scanning might obviate injudicious biopsy and potential hemorrhage within the airway. Utilizing the radionuclide RBC scan, which labels the patient's own RBCs initially with cold pyrophosphate, and subsequently with technetium 99m as pertechnetate, we have identified successfully four patients with cavernous hemangioma of the larynx. All presented with a supraglottic mass involving at least the aryepiglottic fold and arytenoid region unilaterally. This report describes our satisfactory diagnostic imaging experience with the radionuclide RBC scan and suggests both its imaging specificity and its role in the management of this lesion.

  16. Cataract surgery in a case of carotid cavernous fistula

    Directory of Open Access Journals (Sweden)

    Akshay Gopinathan Nair

    2014-01-01

    Full Text Available A carotid-cavernous fistula (CCF is an abnormal communication between the cavernous sinus and the carotid arterial system. The ocular manifestations include conjunctival chemosis, proptosis, globe displacement, raised intraocular pressure and optic neuropathy. Although management of CCF in these patients is necessary, the ophthalmologist may also have to treat other ocular morbidities such as cataract. Cataract surgery in patients with CCF may be associated with many possible complications, including suprachoroidal hemorrhage. We describe cataract extraction surgery in 60-year-old female with bilateral spontaneous low-flow CCF. She underwent phacoemulsification via a clear corneal route under topical anesthesia and had an uneventful postoperative phase and recovered successfully. Given the various possible ocular changes in CCF, one must proceed with an intraocular surgery with caution. In this communication, we wish to describe the surgical precautions and the possible pitfalls in cataract surgery in patients with CCF.

  17. Surgical management of cavernous malformations coursing with drug resistant epilepsy

    OpenAIRE

    Mario Arturo Alonso-Vanegas; Jose Miguel eCisneros-Franco; Taisuke eOtsuki

    2012-01-01

    Cerebral cavernous malformations (CM) are dynamic lesions characterized by continuous size changes and repeated bleeding. When involving cortical tissue, CM pose a significant risk for the development of drug-resistant epilepsy, which is thought to be result of an altered neuronal network caused by the lesion itself and its blood degradation products. Preoperative evaluation should comprise a complete seizure history, neurological examination, epilepsy-oriented MRI, EEG, video-EEG, completed ...

  18. Effects of high glucose on human cavernous endothelial cells.

    Science.gov (United States)

    Ning, Hongxiu; Qiu, Xuefeng; Baine, Lia; Lin, Guiting; Lue, Tom F; Lin, Ching-Shwun

    2012-11-01

    To obtain experimental evidence for a causal effect of high glucose (HG) on cavernous endothelial dysfunction. Cavernous tissues were obtained from patients undergoing surgery for penile prosthesis implantation. Endothelial cells were isolated by binding to anti-CD31 antibody, followed by magnetic capture. Their endothelial identity was verified by flow cytometry and immunofluorescence staining for endothelial markers CD31, von Willebrand factor, and endothelial nitric oxide synthase, and by their ability to form tube-like structures in matrigel (tube formation) and to endocytose acetylated low-density lipoprotein (low-density lipoprotein uptake). The cells were then cultured under normal glucose (NG) (5 mM) or HG (25 mM) conditions, followed by analysis for endothelial gene expression, function, proliferation, apoptosis, and mitochondrial fragmentation. Human cavernous endothelial cell (HCEC) strains were established and determined to be nearly 100% pure endothelial cells. In the HG culture condition, HCECs expressed approximately 50% less CD31, von Willebrand factor, and endothelial nitric oxide synthase, but nearly twice as much collagen IV compared with HCECs grown in NG medium. HG also suppressed low-density lipoprotein uptake and tube formation by approximately 50%. HCECs grew significantly slower in the high-glucose medium than in the NG medium. Approximately 3 times as many cells exhibited apoptosis in the HG medium as in the NG medium. Approximately 4 times as many cells contained fragmented mitochondria in the HG medium as in the NG medium. HG caused a decrease in endothelial proliferation, function, and marker expression. It also caused an increase in endothelial collagen IV expression, apoptosis, and mitochondrial fragmentation. Together, these HG-induced changes in cavernous endothelial cells provide an explanation for hyperglycemia's detrimental effects on erectile function. Copyright © 2012 Elsevier Inc. All rights reserved.

  19. Gas hydrates in gas storage caverns; Gashydrate bei der Gaskavernenspeicherung

    Energy Technology Data Exchange (ETDEWEB)

    Groenefeld, P. [Kavernen Bau- und Betriebs-GmbH, Hannover (Germany)

    1997-12-31

    Given appropriate pressure and temperature conditions the storage of natural gas in salt caverns can lead to the formation of gas hydrates in the producing well or aboveground operating facilities. This is attributable to the stored gas becoming more or less saturated with water vapour. The present contribution describes the humidity, pressure, and temperature conditions conducive to gas hydrate formation. It also deals with the reduction of the gas removal capacity resulting from gas hydrate formation, and possible measures for preventing hydrate formation such as injection of glycol, the reduction of water vapour absorption from the cavern sump, and dewatering of the cavern sump. (MSK) [Deutsch] Bei der Speicherung von Erdgas in Salzkavernen kann es unter entsprechenden Druck- und Temperaturverhaeltnissen zur Gashydratbildung in den Foerdersonden oder obertaegigen Betriebseinrichtungen kommen, weil sich das eingelagerte Gas mehr oder weniger mit Wasserdampf aufsaettigt. Im Folgenden werden die Feuchtigkeits-, Druck- und Temperaturbedingungen, die zur Hydratbildung fuehren erlaeutert. Ebenso werden die Verringerung der Auslagerungskapazitaet durch die Hydratbildung, Massnahmen zur Verhinderung der Hydratbildung wie die Injektion von Glykol, die Verringerung der Wasserdampfaufnahme aus dem Kavernensumpf und die Entwaesserung der Kavernensumpfs selbst beschrieben.

  20. Challenges of constructing salt cavern gas storage in China

    Science.gov (United States)

    Xia, Yan; Yuan, Guangjie; Ban, Fansheng; Zhuang, Xiaoqian; Li, Jingcui

    2017-11-01

    After more than ten years of research and engineering practice in salt cavern gas storage, the engineering technology of geology, drilling, leaching, completion, operation and monitoring system has been established. With the rapid growth of domestic consumption of natural gas, the requirement of underground gas storage is increasing. Because high-quality rock salt resources about 1000m depth are relatively scarce, the salt cavern gas storages will be built in deep rock salt. According to the current domestic conventional construction technical scheme, construction in deep salt formations will face many problems such as circulating pressure increasing, tubing blockage, deformation failure, higher completion risk and so on, caused by depth and the complex geological conditions. Considering these difficulties, the differences between current technical scheme and the construction scheme of twin well and big hole are analyzed, and the results show that the technical scheme of twin well and big hole have obvious advantages in reducing the circulating pressure loss, tubing blockage and failure risk, and they can be the alternative schemes to solve the technical difficulties of constructing salt cavern gas storages in the deep rock salt.

  1. Pythium Keratitis Leading to Fatal Cavernous Sinus Thrombophlebitis.

    Science.gov (United States)

    Rathi, Anubha; Chakrabarti, Arunaloke; Agarwal, Tushar; Pushker, Neelam; Patil, Mukesh; Kamble, Hemant; Titiyal, Jeewan S; Mohan, Rishi; Kashyap, Seema; Sharma, Sanjay; Sen, Seema; Satpathy, Gita; Sharma, Namrata

    2018-04-01

    To report a case of Pythium insidiosum keratitis leading to fatal cavernous sinus thrombophlebitis. Case report. A 70-year-old man presented with excruciating pain, redness, and diminution of vision in his left eye for 2 weeks after washing his hair with tap water. A total corneal ulcer with surrounding infiltrates and associated corneal thinning was present. Corneal scraping revealed the presence of Gram-positive cocci. KOH wet mount and in vivo confocal microscopy revealed branching hyphae. Combined antibacterial and antifungal treatment was started, but 4 days later, the ulcer showed signs of worsening with perforation for which a large therapeutic penetrating keratoplasty was done. The host cornea showed branching septate hyphae on Sabarouds Dextrose Agar. Two weeks later, the patient developed left eye proptosis with associated extraocular movement restriction. Magnetic resonance imaging of the head and orbit revealed cavernous sinus thrombophlebitis. Lid sparing partial exenteration was performed. Polymerase chain reaction revealed P. insidiosum. The patient subsequently developed a cerebrovascular attack and died of its complications. Ocular pythiosis may lead to cavernous sinus thrombophlebitis and can even be life threatening. Timely diagnosis and early radical surgery are of value. A high index of suspicion must be kept for P. insidiosum in cases with suspected fungal etiology not responding to conventional treatment.

  2. Bryan Mound SPR cavern 113 remedial leach stage 1 analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Rudeen, David Keith; Weber, Paula D.; Lord, David L.

    2013-08-01

    The U.S. Strategic Petroleum Reserve implemented the first stage of a leach plan in 2011-2012 to expand storage volume in the existing Bryan Mound 113 cavern from a starting volume of 7.4 million barrels (MMB) to its design volume of 11.2 MMB. The first stage was terminated several months earlier than expected in August, 2012, as the upper section of the leach zone expanded outward more quickly than design. The oil-brine interface was then re-positioned with the intent to resume leaching in the second stage configuration. This report evaluates the as-built configuration of the cavern at the end of the first stage, and recommends changes to the second stage plan in order to accommodate for the variance between the first stage plan and the as-built cavern. SANSMIC leach code simulations are presented and compared with sonar surveys in order to aid in the analysis and offer projections of likely outcomes from the revised plan for the second stage leach.

  3. Outcome of LINAC radiosurgery for a cavernous angioma

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Se Mie; Chie, Eui Kyu; Kim, Il Han; Ha, Sung Whan; Park, Charn Il [College of Medicine, Seoul National Univ., Seoul (Korea, Republic of); Park, Suk Won [College of Medicine, Halym Univ., Seoul (Korea, Republic of)

    2003-03-01

    To establish the role of stereotactic radiosurgery using a linear accelerator for the treatment of patients with cavernous angioma. Between February 1995 and May 1997, 11 patients with cavernous angioma were treated with stereotactic radiosurgery using a linear accelerator. Diagnoses were based on the magnetic resonance imaging in 8 patients, and the histological in 3. The vascular lesions were located in the brainstem (5 cases), cerebellum (2 cases) thalamus (1 case) and cerebrum (3 cases), The clinical presentation at onset included previous intracerebral hemorrhages (9 cases) and seizures (2 cases). All patients were treated with a linac-based radiosurgery. The median dose of radiation delivered was 16 Gy ranging from 14 to 24 Gy, which was typically prescribed to the 80% isodose surface (range 50-80%), corresponding to the periphery of the lesion with a single isocenter. Ten patients were followed-up. The median follow-up was 49 months ranging from 8 to 73 months, during which time two patients developed an intracerebral hemorrhage, 1 at 8 months, with the other at 64 months post radiosurgery. One patient developed neurological deficit after radiosurgery, and two developed an edema on the T2 weighted images of the MRI surrounding the radiosurgical target. The use of stereotactic radiosurgery in the treatment of a cavernous angioma may be effective in the prevention of rebleeding, and can be safely delivered. However, a longer follow-up period will be required.

  4. Endovascular treatment of carotid-cavernous vascular lesions

    Directory of Open Access Journals (Sweden)

    GUILHERME BRASILEIRO DE AGUIAR

    Full Text Available ABSTRACT Objective: to evaluate the endovascular treatment of vascular lesions of the cavernous segment of the internal carotidartery (ICA performed at our institution. Methods: we conducted a descriptive, retrospective and prospective study of patients with aneurysms of the cavernous portion of the ICA or with direct carotid-cavernous fistulas (dCCF undergoing endovascular treatment. Results: we included 26 patients with intracavernous aneurysms and ten with dCCF. All aneurysms were treated with ICA occlusion. Those with dCCF were treated with occlusion in seven cases and with selective fistula occlusion in the remaining three. There was improvement of pain and ocular proptosis in all patients with dCCF. In patients with intracavernous aneurysms, the incidence of retro-orbital pain fell from 84.6% to 30.8% after treatment. The endovascular treatment decreased the dysfunction of affected cranial nerves in both groups, especially the oculomotor one. Conclusion: the endovascular treatment significantly improved the symptoms in the patients studied, especially those related to pain and oculomotor nerve dysfunction.

  5. Geotechnical issues and guidelines for storage of compressed air in excavated hard rock caverns

    Energy Technology Data Exchange (ETDEWEB)

    Allen, R.D.; Doherty, T.J.; Fossum, A.F.

    1982-04-01

    The results of a literature survey on the stability of excavated hard rock caverns are presented. The objective of the study was to develop geotechnical criteria for the design of compressed air energy storage (CAES) caverns in hard rock formations. These criteria involve geologic, hydrological, geochemical, geothermal, and in situ stress state characteristics of generic rock masses. Their relevance to CAES caverns, and the identification of required research areas, are identified throughout the text. This literature survey and analysis strongly suggests that the chief geotechnical issues for the development and operation of CAES caverns in hard rock are impermeability for containment, stability for sound openings, and hydrostatic balance.

  6. Geomechanical Analysis and Design Considerations for Thin-Bedded Salt Caverns. Final Report

    International Nuclear Information System (INIS)

    Michael S. Bruno

    2005-01-01

    The bedded salt formations located throughout the United States are layered and interspersed with non-salt materials such as anhydrite, shale, dolomite and limestone. The salt layers often contain significant impurities. GRI and DOE have initialized this research proposal in order to increase the gas storage capabilities by providing operators with improved geotechnical design and operating guidelines for thin bedded salt caverns. Terralog has summarized the geologic conditions, pressure conditions, and critical design factors that may lead to: (1) Fracture in heterogeneous materials; (2) Differential deformation and bedding plane slip; (3) Propagation of damage around single and multiple cavern; and (4) Improved design recommendations for single and multiple cavern configurations in various bedded salt environments. The existing caverns within both the Permian Basin Complex and the Michigan and Appalachian Basins are normally found between 300 m to 1,000 m (1,000 ft to 3,300 ft) depth depending on local geology and salt dissolution depth. Currently, active cavern operations are found in the Midland and Anadarko Basins within the Permian Basin Complex and in the Appalachian and Michigan Basins. The Palo Duro and Delaware Basins within the Permian Basin Complex also offer salt cavern development potential. Terralog developed a number of numerical models for caverns located in thin bedded salt. A modified creep viscoplastic model has been developed and implemented in Flac3D to simulate the response of salt at the Permian, Michigan and Appalachian Basins. The formulation of the viscoplastic salt model, which is based on an empirical creep law developed for Waste Isolation Pilot Plant (WIPP) Program, is combined with the Drucker-Prager model to include the formation of damage and failure. The Permian salt lab test data provided by Pfeifle et al. 1983, are used to validate the assumptions made in the material model development. For the actual cavern simulations two

  7. Geomechanical Analysis and Design Considerations for Thin-Bedded Salt Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Michael S. Bruno

    2005-06-15

    The bedded salt formations located throughout the United States are layered and interspersed with non-salt materials such as anhydrite, shale, dolomite and limestone. The salt layers often contain significant impurities. GRI and DOE have initialized this research proposal in order to increase the gas storage capabilities by providing operators with improved geotechnical design and operating guidelines for thin bedded salt caverns. Terralog has summarized the geologic conditions, pressure conditions, and critical design factors that may lead to: (1) Fracture in heterogeneous materials; (2) Differential deformation and bedding plane slip; (3) Propagation of damage around single and multiple cavern; and (4) Improved design recommendations for single and multiple cavern configurations in various bedded salt environments. The existing caverns within both the Permian Basin Complex and the Michigan and Appalachian Basins are normally found between 300 m to 1,000 m (1,000 ft to 3,300 ft) depth depending on local geology and salt dissolution depth. Currently, active cavern operations are found in the Midland and Anadarko Basins within the Permian Basin Complex and in the Appalachian and Michigan Basins. The Palo Duro and Delaware Basins within the Permian Basin Complex also offer salt cavern development potential. Terralog developed a number of numerical models for caverns located in thin bedded salt. A modified creep viscoplastic model has been developed and implemented in Flac3D to simulate the response of salt at the Permian, Michigan and Appalachian Basins. The formulation of the viscoplastic salt model, which is based on an empirical creep law developed for Waste Isolation Pilot Plant (WIPP) Program, is combined with the Drucker-Prager model to include the formation of damage and failure. The Permian salt lab test data provided by Pfeifle et al. 1983, are used to validate the assumptions made in the material model development. For the actual cavern simulations two

  8. Risk assessment of nonhazardous oil-field waste disposal in salt caverns

    International Nuclear Information System (INIS)

    Elcock, D.

    1998-01-01

    In 1996, Argonne National Laboratory (ANL) conducted a preliminary technical and legal evaluation of disposing of nonhazardous oil-field wastes (NOW) into salt caverns. Argonne determined that if caverns are sited and designed well, operated carefully, closed properly, and monitored routinely, they could be suitable for disposing of oil-field wastes. On the basis of these findings, Argonne subsequently conducted a preliminary evaluation of the possibility that adverse human health effects (carcinogenic and noncarcinogenic) could result from exposure to contaminants released from the NOW disposed of in domal salt caverns. Steps used in this evaluation included the following: identifying potential contaminants of concern, determining how humans could be exposed to these contaminants, assessing contaminant toxicities, estimating contaminant intakes, and calculating human cancer and noncancer risk estimates. Five postclosure cavern release scenarios were assessed. These were inadvertent cavern intrusion, failure of the cavern seal, failure of the cavern through cracks, failure of the cavern through leaky interbeds, and a partial collapse of the cavern roof. Assuming a single, generic, salt cavern and generic oil-field wastes, potential human health effects associated with constituent hazardous substances (arsenic, benzene, cadmium, and chromium) were assessed under each of these scenarios. Preliminary results provided excess cancer risk and hazard index (referring to noncancer health effects) estimates that were well within the US Environmental Protection Agency (EPA) target range for acceptable exposure risk levels. These results led to the preliminary conclusion that from a human health perspective, salt caverns can provide an acceptable disposal method for nonhazardous oil-field wastes

  9. Analysis of cavern and well stability at the West Hackberry SPR site using a full-dome model.

    Energy Technology Data Exchange (ETDEWEB)

    Sobolik, Steven R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    This report presents computational analyses that simulate the structural response of caverns at the Strategic Petroleum Reserve (SPR) West Hackberry site. The cavern field comprises 22 caverns. Five caverns (6, 7, 8, 9, 11) were acquired from industry and have unusual shapes and a history dating back to 1946. The other 17 caverns (101-117) were leached according to SPR standards in the mid-1980s and have tall cylindrical shapes. The history of the caverns and their shapes are simulated in a three-dimensional geomechanics model of the site that predicts deformations, strains, and stresses. Future leaching scenarios corresponding to oil drawdowns using fresh water are also simulated by increasing the volume of the caverns. Cavern pressures are varied in the model to capture operational practices in the field. The results of the finite element model are interpreted to provide information on the current and future status of subsidence, well integrity, and cavern stability. The most significant results in this report are relevant to Cavern 6. The cavern is shaped like a bowl with a large ceiling span and is in close proximity to Cavern 9. The analyses predict tensile stresses at the edge of the ceiling during repressurization of Cavern 6 following workover conditions. During a workover the cavern is at low pressure to service a well. The wellhead pressures are atmospheric. When the workover is complete, the cavern is repressurized. The resulting elastic stresses are sufficient to cause tension around the edge of the large ceiling span. With time, these stresses relax to a compressive state because of salt creep. However, the potential for salt fracture and propagation exists, particularly towards Cavern 9. With only 200 feet of salt between the caverns, the operational consequences must be examined if the two caverns become connected. A critical time may be during a workover of Cavern 9 in part because of the operational vulnerabilities, but also because dilatant damage

  10. Features of West Hackberry SPR Caverns and Internal Structure Of the Salt Dome

    Energy Technology Data Exchange (ETDEWEB)

    Munson, Darrell Eugene [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Underground Storage Technology Dept.

    2006-09-01

    The intent of this report is to examine the internal structure of the West Hackberry salt dome utilizing the information from the geometric configuration of the internal cavern surfaces obtained from graphical representations of sonar survey data. In a general sense, the caverns of West Hackberry are remarkable in the symmetry of their shapes. There are only rather moderate deviations from what would be considered an ideal cylindrical solution mining geometry in these caverns. This finding is in marked contrast to the directional solutioning found in the elliptical cross sectioned, sometimes winged, caverns of Big Hill. None of the persistent lineaments prevalent in Big Hill caverns are evident in West Hackberry caverns. Irregularities of the West Hackberry caverns are restricted to preferential solution formed pits and protuberances with moderate dimensions. In fact, the principal characteristic of West Hackberry caverns is the often large sections of smooth and cylindrical cavern wall. Differences in the cavern characteristics between West Hackberry and Big Hill suggest that the former dome is quite homogeneous, while the latter still retains strong remnants of the interbeds of the original bedded Louann salt. One possible explanation is that the source of the two domes, while both from the Louann mother salt, differs. While the source of the Big Hill dome is directly from the mother salt bed, it appears that the West Hackberry arises from a laterally extruded sill of the mother salt. Consequently, the amount of deformation, and hence, mixing of the salt and interbed material in the extruded sill is significantly greater than would be the case for the directly formed diapir. In West Hackberry, remnants of interbeds apparently no longer exist. An important aspect of the construction of the West Hackberry caverns is the evidence of an attempt to use a uniform solutioning construction practice. This uniformity involved the utilization of single well solutioning and

  11. Pregnancy-related spinal epidural capillary-cavernous haemangioma: magnetic resonance imaging and differential diagnosis

    International Nuclear Information System (INIS)

    Hakan, T.; Berkman, M.Z.; Demir, M.K.; Aker, F.V.

    2007-01-01

    Full text: Epidural haemangiomas are very rare tumours of the spine. Only a few case reports have been published and most of them were cavernous or capillary. To the best of our knowledge, we report the first case of a histologically confirmed epidural capillary-cavernous haemangioma of the thoracic spine presented in the MRI

  12. Risk assessment of nonhazardous oil-field waste disposal in salt caverns

    International Nuclear Information System (INIS)

    Elcock, D.

    1998-01-01

    Salt caverns can be formed in underground salt formations incidentally as a result of mining or intentionally to create underground chambers for product storage or waste disposal. For more than 50 years, salt caverns have been used to store hydrocarbon products. Recently, concerns over the costs and environmental effects of land disposal and incineration have sparked interest in using salt caverns for waste disposal. Countries using or considering using salt caverns for waste disposal include Canada (oil-production wastes), Mexico (purged sulfates from salt evaporators), Germany (contaminated soils and ashes), the United Kingdom (organic residues), and the Netherlands (brine purification wastes). In the US, industry and the regulatory community are pursuing the use of salt caverns for disposal of oil-field wastes. In 1988, the US Environmental Protection Agency (EPA) issued a regulatory determination exempting wastes generated during oil and gas exploration and production (oil-field wastes) from federal hazardous waste regulations--even though such wastes may contain hazardous constituents. At the same time, EPA urged states to tighten their oil-field waste management regulations. The resulting restrictions have generated industry interest in the use of salt caverns for potentially economical and environmentally safe oil-field waste disposal. Before the practice can be implemented commercially, however, regulators need assurance that disposing of oil-field wastes in salt caverns is technically and legally feasible and that potential health effects associated with the practice are acceptable. In 1996, Argonne National Laboratory (ANL) conducted a preliminary technical and legal evaluation of disposing of nonhazardous oil-field wastes (NOW) into salt caverns. It investigated regulatory issues; the types of oil-field wastes suitable for cavern disposal; cavern design and location considerations; and disposal operations, closure and remediation issues. It determined

  13. Radiosurgical treatment of a carotid-cavernous fistula. Case report

    International Nuclear Information System (INIS)

    Barcia-Salorio, J.L.; Hernandez, G.; Broseta, J.; Ballester, B.; Masbout, G.

    1979-01-01

    This report presents the result obtained in the first patient with a Parkinson Type II spontaneous carotid-cavernous fistula (CCF) cured by means of selective gamma radiation from Co-60. The operation was performed with 25 entrances resulting in a total dose for the target of 2,500 rads. 90% doses were received in a 5 mm diameter spherical volume and 50% doses in a 8 mm volume. One year later, a control carotid angiography showed complete occlusion of the CCF and a normal permeability of the carotid artery. (Auth.)

  14. Uncommon cavernous malformation of the optic chiasm: a case report

    Directory of Open Access Journals (Sweden)

    Ning Xianbin

    2012-08-01

    Full Text Available Abstract Cavernous malformation (CM is a vascular malformation disorder characterized by a berry-like mass of expanded blood vessels. CM, originating from the optic chiasm. usually leads to chiasma syndrome presenting with bitemporal hemianopsia. We report a 28-year-old male presenting with left homonymous hemianopsia. Magnetic resonance imaging (MRI revealed an occupied lesion located in the right side of the optic chiasm, and a clinical diagnosis of chiasmal CM was made. Microsurgical excision was performed via anterolateral pterional craniotomy. The patient showed good recovery with slight improvement of the visual field deficits after the operation. No CM recurrence was discovered during the follow-up MRI scans.

  15. A Giant Cavernous Hemangioma of the Left Atrioventricular Groove

    Directory of Open Access Journals (Sweden)

    Chengming Fan

    2017-01-01

    Full Text Available A 10-year-old Chinese female diagnosed with an asymptomatic giant cardiac cavernous hemangioma was reported. The patient originally tended to observation because this unusual cardiac tumoral mass was discovered incidentally during routine health examination of transthoracic echocardiography. Over 5 years of follow-up, the mass had enlarged obviously, and the patient visited our outpatient clinic and was prone to excision. Subsequently, a total resection surgery of the tumor was performed, and the tumor was found to be located on the left atrioventricular groove with complete packing membrane. The patient was discharged on postoperative day 4 and remains asymptomatic on last follow-up.

  16. Nitrogen Monitoring of West Hackberry 117 Cavern Wells

    Energy Technology Data Exchange (ETDEWEB)

    Bettin, Giorgia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lord, David L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-02-01

    U.S. Strategic Petroleum Reserve (SPR) oil storage cavern West Hackberry 117 was tested under extended nitrogen monitoring following a successful mechanical integrity test in order to validate a newly developed hydrostatic column model to be used to differentiate between normal "tight" well behavior and small-leak behavior under nitrogen. High resolution wireline pressure and temperature data were collected during the test period and used in conjunction with the hydrostatic column model to predict the nitrogen/oil interface and the pressure along the entire fluid column from the bradenhead flange nominally at ground surface to bottom of brine pool. Results here and for other SPR caverns have shown that wells under long term nitrogen monitoring do not necessarily pressurize with a relative rate (P N2 /P brine) of 1. The theoretical relative pressure rate depends on the well configuration, pressure and the location of the nitrogen-oil interface and varies from well to well. For the case of WH117 the predicted rates were 0.73 for well A and 0.92 for well B. The measured relative pressurization rate for well B was consistent with the model prediction, while well A rate was found to be between 0.58-0.68. A number of possible reasons for the discrepancy between the model and measured rates of well A are possible. These include modeling inaccuracy, measurement inaccuracy or the possibility of the presence of a very small leak (below the latest calculated minimum detectable leak rate).

  17. Literature Survey Concerning the Feasibility of Remedial Leach for Select Phase I Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Paula D. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Flores, Karen A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lord, David L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    Bryan Mound 5 ( BM5 ) and West Hackberry 9 ( WH9 ) have the potential to create a significant amount of new storage space should the caverns be deemed "leach - ready". This study discusses the original drilling history of the caverns, surrounding geology, current stability, and, based on this culmination of data, makes a preliminary assessment of the leach potential for the cavern. The risks associated with leaching BM5 present substantial problems for the SPR . The odd shape and large amount of insoluble material make it difficult to de termine whether a targeted leach would have the desired effect and create useable ullage or further distort the shape with preferential leaching . T he likelihood of salt falls and damaged or severed casing string is significant . In addition, a targeted le ach would require the relocation of approximately 27 MMB of oil . Due to the abundance of unknown factors associated with this cavern, a targeted leach of BM5 is not recommended. A targeted leaching of the neck of WH 9 could potentially eliminate or diminis h the mid - cavern ledge result ing in a more stable cavern with a more favorable shape. A better understanding of the composition of the surrounding salt and a less complicated leaching history yields more confidence in the ability to successfully leach this region. A targeted leach of WH9 can be recommended upon the completion of a full leach plan with consideration of the impacts upon nearby caverns .

  18. Assessment of the Available Drawdowns for Oil Storage Caverns at the West Hackberry SPR Site

    Energy Technology Data Exchange (ETDEWEB)

    Sobolik, Steven R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Geotechnology and Engineering Dept.

    2016-03-01

    The Department of Energy, in response to requests from the U.S. Congress, wishes to maintain an up-to-date table documenting the number of available full drawdowns of each of the caverns owned by the Strategic Petroleum Reserve. This information is important for assessing the SPR’s ability to deliver oil to domestic oil companies expeditiously if national or world events dictate a rapid sale and deployment of the oil reserves. What factors go into assessing available drawdowns? The evaluation of drawdown risks require the consideration of several factors regarding cavern and wellbore integrity and stability, including stress states caused by cavern geometry and operations, salt damage caused by dilatant and tensile stresses, the effect on enhanced creep on wellbore integrity, the sympathetic stress effect of operations on neighboring caverns. Based on the work over the past several months, a consensus has been built regarding the assessment of drawdown capabilities and risks for the SPR caverns. This paper draws upon the recently West Hackberry model upgrade and analyses to reevaluate and update the available drawdowns for each of those caverns. Similar papers for the Bryan Mound, Big Hill, and Bayou Choctaw papers will be developed as the upgrades to those analyses are completed. The rationale and documentation of the methodology is described in the remainder of this report, as are the updated estimates of available drawdowns for the West Hackberry caverns.

  19. Cavernous sinus syndrome due to osteochondromatosis in a cat.

    Science.gov (United States)

    Perazzi, Anna; Bernardini, Marco; Mandara, Maria T; De Benedictis, Giulia M; De Strobel, Francesca; Zotti, Alessandro

    2013-12-01

    A 1-year-old sexually intact male Korat cat was referred for ophthalmological consultation due to anisocoria. Mydriasis with external ophthalmoplegia and absence of pupillary light responses in the right eye and nasofacial hypalgesia were seen. Cavernous sinus syndrome (CSS) was suspected. Bilateral deformities of the jaw and phalangeal bones, severe spinal pain and abnormal conformation of the lumbar spine were also present. Radiographic examination revealed several mineralised masses in the appendicular and axial skeleton, indicative of multiple cartilaginous exostoses. For further investigation of the CSS-related neurological deficits, the cat underwent computed tomography (CT) examination of the skull. CT images revealed a non-vascularised, calcified, amorphous mass originating from the right lateral skull base and superimposing on the sella turcica. Based on the severity of diffuse lesions and owing to the clinical signs of extreme pain, the cat was euthanased. A diffuse skeletal and intracranial osteochondromatosis was diagnosed histologically.

  20. Intramedullary cavernous hemangiomas, magnetic resonance studies in four patients

    International Nuclear Information System (INIS)

    Barrena, M.R.; Guelbenzu, S.; Garcia, S.; Bertrol, V.

    1998-01-01

    Intramedullary cavernous hemangiomas are vascular malformations that can be located throughout the entire central nervous system. They are more frequently found in brain than in spinal cord, where it is only possible to diagnose them by magnetic resonance (RM): We present four cases of intramedullary spinal cord cavernoma, three of which were located in the thoracic spine and one in cervical spine. Computed tomography was ineffective in their diagnosis. However, MR disclosed there presence of well-defined tumors producing a thickening of the spinal cord. The signal was heterogeneous in both T1 and T2-weighted images. There were low signal areas due to the presence of calcium and hemosiderin and high intensity signals provoked by methemoglobin within the lesions, which were scarcely enhanced by intravenous gadolinium administration. One of the lesions presented in the form of a large intramedullary hematoma. (Author) 8 refs

  1. Management of Cerebral Cavernous Malformations: From Diagnosis to Treatment

    Directory of Open Access Journals (Sweden)

    Nikolaos Mouchtouris

    2015-01-01

    Full Text Available Cerebral cavernous malformations are the most common vascular malformations and can be found in many locations in the brain. If left untreated, cavernomas may lead to intracerebral hemorrhage, seizures, focal neurological deficits, or headaches. As they are angiographically occult, their diagnosis relies on various MR imaging techniques, which detect different characteristics of the lesions as well as aiding in planning the surgical treatment. The clinical presentation and the location of the lesion are the most important factors involved in determining the optimal course of treatment of cavernomas. We concisely review the literature and discuss the advantages and limitations of each of the three available methods of treatment—microsurgical resection, stereotactic radiosurgery, and conservative management—depending on the lesion characteristics.

  2. Emergency treatment by intravascular embolization in traumatic carotid cavernous fistula

    International Nuclear Information System (INIS)

    Tang Jun; Sun Zengtao; Liu Zuoqin; Liu Yanjun; Li Fengxin

    2006-01-01

    Objective: To discuss the method of intervenfional intravascular treatment in traumatic carotid cavernous fistula (TCCF) and the significance of clinical application in emergency. Methods: In 297 eases of TCCF, 36 cases were treated by interventional intravascular embolization by detachable balloon, embolization orificium or occlusion in one side of carotid artery. In the 36 cases, serious epistaxis occurred in 22 eases, cortical vein inflow in 9 cases, intracranial hemorrhage in 3 cases, aggravation of eyesight in 3 cases, and limb dysfunction in 2 cases. Results: Fistula was successfully embolized and internal carotid artery remained patent in 19 cases. Complete embolization of orificium or internal carotid artery was achieved in 17 eases. The serious epistaxias in 22 cases and intracranial hemorrhage in 3 cases stopped. Eyesight recovered in 2 eases and improved in 1 case. Limb dysfunction improved evidently in 2 cases. Conclusion: Intravascular embolization treatment is the first therapeutic choice for TCCF, especially in emergency. It is necessary, safe and effective. (authors)

  3. Observations on vapor pressure in SPR caverns : sources.

    Energy Technology Data Exchange (ETDEWEB)

    Munson, Darrell Eugene

    2010-05-01

    The oil of the Strategic Petroleum Reserve (SPR) represents a national response to any potential emergency or intentional restriction of crude oil supply to this country, and conforms to International Agreements to maintain such a reserve. As assurance this reserve oil will be available in a timely manner should a restriction in supply occur, the oil of the reserve must meet certain transportation criteria. The transportation criteria require that the oil does not evolve dangerous gas, either explosive or toxic, while in the process of transport to, or storage at, the destination facility. This requirement can be a challenge because the stored oil can acquire dissolved gases while in the SPR. There have been a series of reports analyzing in exceptional detail the reasons for the increases, or regains, in gas content; however, there remains some uncertainty in these explanations and an inability to predict why the regains occur. Where the regains are prohibitive and exceed the criteria, the oil must undergo degasification, where excess portions of the volatile gas are removed. There are only two known sources of gas regain, one is the salt dome formation itself which may contain gas inclusions from which gas can be released during oil processing or storage, and the second is increases of the gases release by the volatile components of the crude oil itself during storage, especially if the stored oil undergoes heating or is subject to biological generation processes. In this work, the earlier analyses are reexamined and significant alterations in conclusions are proposed. The alterations are based on how the fluid exchanges of brine and oil uptake gas released from domal salt during solutioning, and thereafter, during further exchanges of fluids. Transparency of the brine/oil interface and the transfer of gas across this interface remains an important unanswered question. The contribution from creep induced damage releasing gas from the salt surrounding the cavern is

  4. An Unusual Differential Diagnosis of Orbital Cavernous Hemangioma: Ancient Schwannoma

    Directory of Open Access Journals (Sweden)

    Sara Filipa Teixeira Ribeiro

    2017-05-01

    Full Text Available Schwannomas are rare lesions of the orbit that can be confused with cavernous hemangioma on imaging studies. We report the case of an 84-year-old woman with a 9-year history of a tumoral lesion in the inferolateral left orbit. The imaging studies did not reveal specific characteristics, only bone remodeling due to the long evolution of the tumor. The patient underwent complete excision of the tumor by anterior orbitotomy via the inferior conjunctival fornix. The histopathological examination revealed an ancient schwannoma, a variant of schwannoma with uncommon histological features. The follow-up was uneventful. The present case emphasizes the importance of considering neural tumors in the differential diagnosis of orbital masses with bone changes and degenerative alterations such as hemorrhagic areas, cysts, and/or calcifications.

  5. Sonographic Findings of Cavernous Hemangioma in Fatty Liver

    International Nuclear Information System (INIS)

    Hahm, Jin Kyeung; Kim, Ki Whang; Yoon, Sang Wook; Kim, Tae Hoon; Lee, Jong Tae; Yoo, Hyung Sik; Kim, Myung Jin; Ji, Hoon

    1995-01-01

    Typical cavernous hemangioma presents no diagnostic difficulty at sonography. However, in cases of atypical hemangioma, further evaluation is needed to differentiate it from malignancy. On the other hand, thcechogenicity of the lesion may be iso echo or hypoecho when it occurs in association with fatty liver. We analyzed the sonographic features of hemangioma in fatty liver. We reviewed the sonograms of 22 lesions from 19 patients. We divided the lesions into two groups; the lesion measuring less than 3cm in diameter (group I) and the lesions measuring same or greater than 3cm (group II). The lesions of each group were analyzed in terms of location, shape, distinction of margin, internal echogenicity, posterior enhancement, lateral shadowing, and peritumoral hypoechoic halo. The lesions were located in subcapsular or perivascular areain 86%. They strowed round or lobulated shape with well defined margin in 82%. Internal echo of the lesions was hypoechoic in 82% and homogeneous in 64%. Posterior enhancement was seen in 77%. The posterior wall of the lesion was distinct in 68%. There was no statistical difference in incidence of each finding described above between the two groups except the internal echogenicity(p<0.05). All of the four hyperechoic lesions measured greater than 3cmin diameter, and three of them showed uneven thickness of echogenic rind. Definitive diagnosis of hemangioma could be obtained in 82%. In remaining 18% of hemangioma, the lesions showed peripheral hypoechoic halo and lateral shadowing that made the diagnosis of hemangioma difficult. However, the possibility of hemangioma could be suggested because they showed haemangiomas internal eye-catching and posterior enhancement. Hepatic cavernous hemangioma presents with variable eye-catching as compared to the surrounding tissue when it is associated with fatty liver disease, Thus, in differentiating hemangiomas from other localized hepatic mass, other characteristics such as homogeneity of the

  6. Dural cavernous sinus fistulas. Diagnostic and endovascular therapy

    International Nuclear Information System (INIS)

    Benndorf, Goetz; Ben Taub General Hospital, Houston, TX

    2010-01-01

    Dural cavernous sinus fistulas (DCSFs) represent a benign vascular disease, consisting in an arteriovenous shunt at the cavernous sinus. In the absence of spontaneous resolution, the fistula may lead to eye redness, swelling, proptosis, chemosis, ophthalmoplegia and visual loss. Although modern imaging techniques have improved the diagnostic, patients with low-flow DCSFs are still misdiagnosed. These patients can get erroneously treated for infections and inflammation for months or years and are at risk of visual loss. Early and proper diagnosis helps to avoid deleterious clinical course of the disease. This volume provides a complete guide to clinical and radiological diagnosis as well as to therapeutic management of DCSF with emphasis on modern minimal invasive treatment options. It commences with an informative description of relevant anatomy. After sections on the classification, etiology and pathogenesis of DCSF, the clinical symptomatology of the disease is described in detail. The role of modern non-invasive imaging tools is then addressed with the use of computed tomography, magnetic resonance imaging and ultrasound. Intra-arterial digital subtraction angiography (DSA), although invasive, remains the gold standard and is mandatory for clinical decision-making and strategy in endovascular treatment. Hence, a throughout consideration is given to both, 2D-DSA and 3D rotational angiography, including recent technological advancements such as Dual Volume (DV) imaging and angiographic computed tomography (ACT). After a short section on arteriovenous hemodynamics, the therapeutic management of DCSFs is described in detail. In particular, various transvenous techniques, required for successful endovascular occlusion of DCSF, are discussed in depth. This well-illustrated volume will be invaluable to all who may encounter DCSF in their clinical practice. (orig.)

  7. Transient behaviour of deep underground salt caverns; Comportement transitoire des cavites salines profondes

    Energy Technology Data Exchange (ETDEWEB)

    Karimi-Jafari, M

    2007-11-15

    This work deals with the transient behaviour of deep underground salt caverns. It has been shown that a cavern is a complex system, in which there are mechanical, thermal, chemical and hydraulic evolutions. The importance of the transient evolutions, particularly the role of the 'reverse' creep in the interpretation of the tightness test in a salt cavern is revealed. Creep is characterized by a formulation of the behaviour law which presents the advantage, in a practical point of view, to only have a reduced number of parameters while accounting of the essential of what it is observed. The initiation of the rupture in the effective traction in a salt cavern rapidly pressurized is discussed. A model fitted to a very long term behaviour (after abandonment) is developed too. In this case too, a lot of phenomena, more or less coupled, occur, when the existing literature took only into account some phenomena. (O.M.)

  8. VACUUM THERAPY – PREVENTION OF HYPOXIA OF CAVERNOUS TISSUE PATIENTS AFTER RADICAL PROSTATECTOMY

    Directory of Open Access Journals (Sweden)

    A. E. Osadchinskii

    2018-01-01

    Full Text Available Patients, after radical prostatectomy with the use of nerve-sparing techniques, without carrying out penile rehabilitation, are at risk of forming cavernous fibrosis with the emergence of subsequent persistent erectile dysfunction. In order to minimize damage to cavernous tissue and early restoration of erectile function during the period of neuropraxia, it is necessary to ensure a sufficient level of oxygenation. The role of applying vacuum in penile rehabilitation for the prevention of hypoxia of cavernous tissue is not fully understood, due to the lack of data on the gaseous composition of the blood at the time of reaching the vacuum of erection. The purpose of this work was to review the scientific studies devoted to the study of vacuum induced penile erection in animals or humans, which indicates high results due to increased oxygenation of cavernous tissue.

  9. Preliminary Technical and Legal Evaluation of Disposing of Nonhazardous Oil Field Waste into Salt Caverns

    National Research Council Canada - National Science Library

    Veil, John

    1996-01-01

    .... These caverns are either created incidentally as a result of salt recovery or intentionally to create an underground chamber that can be used for storing hydrocarbon products or compressed air...

  10. Transorbital superior ophthalmic vein sacrifice to preserve vision in ocular hypertension from aseptic cavernous sinus thrombosis.

    Science.gov (United States)

    Ladner, Travis R; Davis, Brandon J; He, Lucy; Mawn, Louise A; Mocco, J

    2015-12-01

    Aseptic cavernous sinus thrombosis (CST) is rare and may clinically masquerade as a carotid cavernous fistula. Conventional management includes oral anticoagulation, but cases of ocular hypertension affecting vision may require more aggressive intervention. We report a case of a woman with spontaneous bilaterally occluded cavernous sinuses with elevated intraocular pressure (IOP), which resolved immediately following unilateral superior ophthalmic vein (SOV) sacrifice. She was subsequently placed on oral anticoagulants. By 4 months postoperatively her IOP was normalized and her vision had improved. Repeat angiography demonstrated stable venous filling, with some mild improvement of flow through the cavernous sinus. Coil-mediated sacrifice of the SOV might be an effective means to relieve ocular hypertension and preserve vision in the setting of aseptic CST. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  11. EXAMINE AND EVALUATE A PROCESS TO USE SALT CAVERNS TO RECEIVE SHIP BORNE LIQUEFIED NATURAL GAS

    Energy Technology Data Exchange (ETDEWEB)

    Michael M. McCall; William M. Bishop; D. Braxton Scherz

    2003-04-24

    The goal of the U.S. Department of Energy cooperative research project is to define, describe, and validate, a process to utilize salt caverns to receive and store the cargoes of LNG ships. The project defines the process as receiving LNG from a ship, pumping the LNG up to cavern injection pressures, warming it to cavern compatible temperatures, injecting the warmed vapor directly into salt caverns for storage, and distribution to the pipeline network. The performance of work under this agreement is based on U.S. Patent 5,511,905, and other U.S. and Foreign pending patent applications. The cost sharing participants in the research are The National Energy Technology Laboratory (U.S. Department of Energy), BP America Production Company, Bluewater Offshore Production Systems (U.S.A.), Inc., and HNG Storage, L.P. Initial results indicate that a salt cavern based receiving terminal could be built at about half the capital cost, less than half the operating costs and would have significantly higher delivery capacity, shorter construction time, and be much more secure than a conventional liquid tank based terminal. There is a significant body of knowledge and practice concerning natural gas storage in salt caverns, and there is a considerable body of knowledge and practice in handling LNG, but there has never been any attempt to develop a process whereby the two technologies can be combined. Salt cavern storage is infinitely more secure than surface storage tanks, far less susceptible to accidents or terrorist acts, and much more acceptable to the community. The project team developed conceptual designs of two salt cavern based LNG terminals, one with caverns located in Calcasieu Parish Louisiana, and the second in Vermilion block 179 about 50 miles offshore Louisiana. These conceptual designs were compared to conventional tank based LNG terminals and demonstrate superior security, economy and capacity. The potential for the development of LNG receiving terminals

  12. A rare case of abnormal uterine bleeding caused by cavernous hemangioma: a case report

    OpenAIRE

    Benjamin, Mridula A; Yaakub, Hjh Roselina; Telesinghe, PU; Kafeel, Gazala

    2010-01-01

    Abstract Introduction Cavernous hemangiomas of the uterus are extremely rare, benign lesions. A survey of the current literature identified fewer than 50 cases of hemangioma of the uterus. Case presentation We report a case of cavernous hemangioma of the uterus in a 27-year-old Malay, para 1 woman who presented at our hospital with torrential vaginal bleeding having been transferred by land ambulance from a district hospital 30 minutes away. 11 weeks previously she had an urgent cesarean sect...

  13. Disposal of NORM-Contaminated Oil Field Wastes in Salt Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Blunt, D.L.; Elcock, D.; Smith, K.P.; Tomasko, D.; Viel, J.A.; and Williams, G.P.

    1999-01-21

    In 1995, the U.S. Department of Energy (DOE), Office of Fossil Energy, asked Argonne National Laboratory (Argonne) to conduct a preliminary technical and legal evaluation of disposing of nonhazardous oil field waste (NOW) into salt caverns. That study concluded that disposal of NOW into salt caverns is feasible and legal. If caverns are sited and designed well, operated carefully, closed properly, and monitored routinely, they can be a suitable means of disposing of NOW (Veil et al. 1996). Considering these findings and the increased U.S. interest in using salt caverns for NOW disposal, the Office of Fossil Energy asked Argonne to conduct further research on the cost of cavern disposal compared with the cost of more traditional NOW disposal methods and on preliminary identification and investigation of the risks associated with such disposal. The cost study (Veil 1997) found that disposal costs at the four permitted disposal caverns in the United States were comparable to or lower than the costs of other disposal facilities in the same geographic area. The risk study (Tomasko et al. 1997) estimated that both cancer and noncancer human health risks from drinking water that had been contaminated by releases of cavern contents were significantly lower than the accepted risk thresholds. Since 1992, DOE has funded Argonne to conduct a series of studies evaluating issues related to management and disposal of oil field wastes contaminated with naturally occurring radioactive material (NORM). Included among these studies were radiological dose assessments of several different NORM disposal options (Smith et al. 1996). In 1997, DOE asked Argonne to conduct additional analyses on waste disposal in salt caverns, except that this time the wastes to be evaluated would be those types of oil field wastes that are contaminated by NORM. This report describes these analyses. Throughout the remainder of this report, the term ''NORM waste'' is used to mean &apos

  14. Fractal Prediction of Grouting Volume for Treating Karst Caverns along a Shield Tunneling Alignment

    Directory of Open Access Journals (Sweden)

    Wen-Chieh Cheng

    2017-06-01

    Full Text Available Karst geology is common in China, and buried karst formations are widely distributed in Guangdong province. In the process of shield tunneling, the abundant water resources present in karst caverns could lead to the potential for high water ingress, and a subsequent in situ stress change-induced stratum collapse. The development and distribution of karst caverns should therefore be identified and investigated prior to shield tunnel construction. Grouting is an efficient measure to stabilize karst caverns. The total volume of karst caverns along the shield tunneling alignment, and its relationship with the required volume of grouts, should be evaluated in the preliminary design phase. Conventionally, the total volume of karst caverns is empirically estimated based on limited geological drilling hole data; however, accurate results are rarely obtained. This study investigates the hydrogeology and engineering geology of Guangzhou, the capital of Guangdong province, and determines the fractal characteristics of the karst caverns along the tunnel section of Guangzhou metro line no. 9. The karst grouting coefficients (VR were found to vary from 0.11 in the case of inadequate drilling holes to 1.1 in the case where adequate drilling holes are provided. A grouting design guideline was furthermore developed in this study for future projects in karst areas.

  15. Risk analyses for disposing nonhazardous oil field wastes in salt caverns

    Energy Technology Data Exchange (ETDEWEB)

    Tomasko, D.; Elcock, D.; Veil, J.; Caudle, D.

    1997-12-01

    Salt caverns have been used for several decades to store various hydrocarbon products. In the past few years, four facilities in the US have been permitted to dispose nonhazardous oil field wastes in salt caverns. Several other disposal caverns have been permitted in Canada and Europe. This report evaluates the possibility that adverse human health effects could result from exposure to contaminants released from the caverns in domal salt formations used for nonhazardous oil field waste disposal. The evaluation assumes normal operations but considers the possibility of leaks in cavern seals and cavern walls during the post-closure phase of operation. In this assessment, several steps were followed to identify possible human health risks. At the broadest level, these steps include identifying a reasonable set of contaminants of possible concern, identifying how humans could be exposed to these contaminants, assessing the toxicities of these contaminants, estimating their intakes, and characterizing their associated human health risks. The contaminants of concern for the assessment are benzene, cadmium, arsenic, and chromium. These were selected as being components of oil field waste and having a likelihood to remain in solution for a long enough time to reach a human receptor.

  16. Japan's exploration of vertical holes and subsurface caverns on the Moon and Mars

    Science.gov (United States)

    Haruyama, J.; Kawano, I.; Kubota, T.; Yoshida, K.; Kawakatsu, Y.; Kato, H.; Otsuki, M.; Watanabe, K.; Nishibori, T.; Yamamoto, Y.; Iwata, T.; Ishigami, G.; Yamada, T. T.

    2013-12-01

    Recently, gigantic vertical holes exceeding several tens of meters in diameter and depth were discovered on the Moon and Mars. Based on high-resolution image data, lunar holes and some Martian pits (called 'holes' hereafter) are probably skylights of subsurface caverns such as lava tubes or magma chambers. We are starting preparations for exploring the caverns through the vertical holes. The holes and subsurface caverns have high potential as resources for scientific studies. Various important geological and mineralogical processes could be uniquely and effectively observed inside these holes and subsurface caverns. The exposed fresh lava layers on the vertical walls of the lunar and Martian holes would provide information on volcanic eruption histories. The lava layers may also provide information on past magnetic fields of the celestial bodies. The regolith layers may be sandwiched between lava layers and may preserve volatile elements including solar wind protons that could be a clue to understanding past solar activities. Water molecules from solar winds or cometary/meteorite impacts may be stored inside the caverns because of mild temperatures there. The fresh lava materials forming the walls and floors of caverns might trap endogenic volatiles from magma eruptions that will be key materials for revealing the formation and early evolution of the Moon and Mars. Furthermore, the Martian subsurface caverns are highly expected to be life cradles where the temperatures are probably stable and that are free from ultra-violet and other cosmic rays that break chemical bonds, thus avoiding polymerization of molecules. Discovering extraterrestrial life and its varieties is one of our ultimate scientific purposes for exploring the lunar and Martian subsurface caverns. In addition to scientific interests, lunar and Martian subsurface caverns are excellent candidates for future lunar bases. We expect such caverns to have high potential due to stable temperatures; absence

  17. Advanced Underground Gas Storage Concepts: Refrigerated-Mined Cavern Storage, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    none

    1998-09-30

    Over the past 40 years, cavern storage of LPG's, petrochemicals, such as ethylene and propylene, and other petroleum products has increased dramatically. In 1991, the Gas Processors Association (GPA) lists the total U.S. underground storage capacity for LPG's and related products of approximately 519 million barrels (82.5 million cubic meters) in 1,122 separate caverns. Of this total, 70 are hard rock caverns and the remaining 1,052 are caverns in salt deposits. However, along the eastern seaboard of the U.S. and the Pacific northwest, salt deposits are not available and therefore, storage in hard rocks is required. Limited demand and high cost has prevented the construction of hard rock caverns in this country for a number of years. The storage of natural gas in mined caverns may prove technically feasible if the geology of the targeted market area is suitable; and economically feasible if the cost and convenience of service is competitive with alternative available storage methods for peak supply requirements. Competing methods include LNG facilities and remote underground storage combined with pipeline transportation to the area. It is believed that mined cavern storage can provide the advantages of high delivery rates and multiple fill withdrawal cycles in areas where salt cavern storage is not possible. In this research project, PB-KBB merged advanced mining technologies and gas refrigeration techniques to develop conceptual designs and cost estimates to demonstrate the commercialization potential of the storage of refrigerated natural gas in hard rock caverns. DOE has identified five regions, that have not had favorable geological conditions for underground storage development: New England, Mid-Atlantic (NY/NJ), South Atlantic (DL/MD/VA), South Atlantic (NC/SC/GA), and the Pacific Northwest (WA/OR). PB-KBB reviewed published literature and in-house databases of the geology of these regions to determine suitability of hard rock formations for siting

  18. A benchmark approach to hemorrhage risk management of cavernous malformations.

    Science.gov (United States)

    Kashefiolasl, Sepide; Bruder, Markus; Brawanski, Nina; Herrmann, Eva; Seifert, Volker; Tritt, Stephanie; Konczalla, Juergen

    2018-02-02

    Despite the low annual risk of hemorrhage associated with a cavernous malformation (CM) (0.6%-1.1% per year), the risk of rehemorrhage rate and severity of neurologic deficits is significantly higher; therefore, we aimed to evaluate the rupture risk of CMs depending on various factors. We retrospectively analyzed medical records of all patients with CM admitted to our institution between 1999 and April 2016. Cavernoma volume, location of the lesion, existence of a developmental venous anomaly (DVA), number of cavernomas, and patient characteristics (sex, age, hypertension, and antithrombotic therapy) were assessed. One hundred fifty-four patients with CM were included; 89 (58%) ruptured CMs were identified. In statistical univariable analysis, the existence of a DVA was significantly higher in the ruptured cavernoma group ( p DVA ( p DVA ( p DVA are associated with a higher hemorrhage risk. CM volume (≥1 cm 3 ) and the existence of a DVA were independently in accordance with the anatomical location high risk factors for CM rupture. © 2018 American Academy of Neurology.

  19. Treatment Outcome Of Seizures Associated With Intracranial Cavernous Angiomas

    Directory of Open Access Journals (Sweden)

    Nievera Conrad C

    1999-01-01

    Full Text Available Seizures are among the typical presentations of intracranial cavernous angiomas (ICA. Twenty-one patients (age range: 2 to 53 years treated for seizures associated with ICA between 1983 and 1997 were restrospectively studied to evaluate their outcome following medical or surgical intervention. The mean interval between seizure onset and initial presentation at our institution was 7.6 years. Seizures were simple partial in 3 patients, complex partial in 15 and secondarily generalized tonic-clonic in 13. The commonest site of the lesion was the temporal lobe (52%. Multiple angiomas were observed in 5 (24% patients. Seven (32% patients were medically-managed with antiepileptic therapy and 14 (68% underwent either lesionectomy with resection of the epileptogenic zone (9 patients or temporal lobectomy (5 patients. Mean follow-up time was 4 years (range: 3 months to 14 years. Of the medically-managed patients, 3 (43% remained seizure-free whereas 4 (57% continued to have seizures with an average frequency of one per day. Of the surgically-managed patients, 12 (86% became seizure-free and 2 (14% had no more than two seizures per year. Surgery appears to be extremely effective in the management of seizures associated with ICA and should receive a strong and early consideration in patients who fail medical therapy.

  20. The anatomical location and laterality of orbital cavernous haemangiomas.

    Science.gov (United States)

    McNab, Alan A; Selva, Dinesh; Hardy, Thomas G; O'Donnell, Brett

    2014-10-01

    To determine the anatomical location and laterality of orbital cavernous haemangiomas (OCH). Retrospective case series. The records of 104 patients with OCH were analyzed. The anatomical location of each OCH defined by the location of a point at the centre of the lesion, and its laterality. There were 104 patients included in the study. No patient had more than one lesion. Sixteen (15.4%) were located in the anterior third of the orbit, 74 (71.2%) were in the middle third, and 14 (13.5%) in the posterior third. In the middle third, 10 of 74 (13.5%) were extraconal and 64 intraconal (86.5%), with 30 of 64 (46.9%) middle third intraconal lesions lying lateral to the optic nerve. Of 104 lesions, 56 (53.8%) were left sided, showing a trend towards a predilection for the left side (p = 0.065). If data from other published series which included data on laterality is added to our own data and analysed, 270 of 468 (57.7%) OCH occurred in the left orbit (p lateral to the optic nerve. This may reflect an origin of these lesions from the arterial side of the circulation, as there are more small arteries in the intraconal space lateral to the optic nerve than in other locations. A predilection for the left orbit remains unexplained.

  1. Surgical management of cavernous malformations coursing with drug resistant epilepsy

    Directory of Open Access Journals (Sweden)

    Mario Arturo Alonso-Vanegas

    2012-01-01

    Full Text Available Cerebral cavernous malformations (CM are dynamic lesions characterized by continuous size changes and repeated bleeding. When involving cortical tissue, CM pose a significant risk for the development of drug-resistant epilepsy, which is thought to be result of an altered neuronal network caused by the lesion itself and its blood degradation products. Preoperative evaluation should comprise a complete seizure history, neurological examination, epilepsy-oriented MRI, EEG, video-EEG, completed with SPECT, PET, functional MRI and/or invasive monitoring as needed. Radiosurgery shows variable rates of seizure freedom and a high incidence of complications, thus microsurgical resection remains the optimal treatment for CM coursing with drug-resistant epilepsy.Two thirds of patients reach Engel I class at three-year follow-up, regardless of lobar location. Those with secondarily generalized seizures, a higher seizure frequency, and generalized abnormalities on preoperative or postoperative EEG, show poorer outcomes, while factors such as gender, duration of epilepsy, lesion size, age, bleeding at the time of surgery, do not correlate consistently with seizure outcome. Electrocorticography and a meticulous removal of all cortical hemosiderin –beyond pure lesionectomy– reduce the risk of symptomatic recurrences.

  2. [Cavernous angiomas in the Department of Neurosurgery in Katowice].

    Science.gov (United States)

    Gamrot, Jacek; Bazowski, Piotr; Rudnik, Adam; Zawadzki, Tomasz

    2005-01-01

    166 patients with arterio-venous malformations (AVM) were treated in the Department of Neurosurgery at Silesian School of Medicine from 1987 to 2002. There were 30 (18%) patients diagnosed as cavernous angioma (CA). The oldest treated patient was 73 years old and the youngest one was 5 years old. 16 (55%) male and 14 (45%) female were examined and the results of this examination are presented below. The location of CA was as follows: supratentorially--19 patients (64%), infratentorially--6 patients (20%), extracranially--5 patients (16%). During the admission the clinical status of patients were evaluated according to Glasgow Coma Scale (GCS) and Hunt-Hess scale (H-H). Epilepsy occurred in 5 patients (16%), neurological focal deficits--14 (45%), intracranial hemorrhage--7 (23%). All patients were examined using CT (computer tomography) scan, cerebral angiography was carried out in 15 (50%) patients and MRI (magnetic resonance imaging) in 16 (55%). All patients were operated on in our medical centre. The results of treatment were presented according to Glasgow Outcome Scale (GOS).

  3. Endoscopic endonasal resection of cavernous hemangioma of the palate

    Directory of Open Access Journals (Sweden)

    Kristina Piastro

    2017-11-01

    Full Text Available Hemangiomas are a common presentation in the head and neck, but intraosseous hemangiomas are exceedingly rare and account for only 1% of bone tumors. The hard palate is a unique anatomic structure consisting of mucosa rich in minor salivary glands, and is firmly attached to the palatine process of the maxilla and the horizontal plate of the palatine bone. Neoplasms of the hard palate are extremely rare and may display unique characteristics and histologic findings. Whether benign or malignant, the therapy of choice for such tumors is surgical excision performed through a transoral approach, which carries a significant risk of oronasal and oroantral fistula formation. This paper describes the use of an endoscopic endonasal technique for resection of a rare case of a cavernous hemangioma of the hard palate. Resection of favorable benign lesions like palatal hemangiomas are more likely to be successful via this endoscopic endonasal technique which avoids the traditional transoral palatal approach and thus reduces the risk of oronasal and oroantral fistulae. No complications in the immediate postoperative nor within a 1-year follow-up period were observed.

  4. Induced Seismicity Monitoring of an Underground Salt Cavern Prone to Collapse

    Science.gov (United States)

    Mercerat, E. D.; Driad-Lebeau, L.; Bernard, P.

    2010-02-01

    Within the framework of a large research project launched to assess the feasibility of microseismic monitoring of growing underground caverns, this specific work focuses on the analysis of the induced seismicity recorded in a salt mine environment. A local seismic network has been installed over an underground salt cavern located in the Lorraine basin (Northeast of France). The microseismic network includes four 3-components and three single component geophones deployed at depths between 30 and 125 m in cemented boreholes drilled in the vicinity of the study area. The underground cavern under monitoring is located within a salt layer at 180 m depth and it presents a rather irregular shape that can be approximated by a cylindrical volume of 50 m height and 180 m diameter. Presently, the cavern is full of saturated brine inducing a significant pressure on its walls (~2.0 MPa) to keep the overburden mechanically stable. Nevertheless some small microseismic events were recorded by the network and analyzed (approximately 2,000 events in 2 years of recording). In October 2005 and April 2007, two controlled pressure transient experiments were carried out in the cavern, in order to analyze the mechanical response of the overburden by tracking the induced microseismicity. The recorded events were mainly grouped in clusters of 3-30 s of signal duration with emergent first arrivals and rather low frequency content (between 20 and 120 Hz). Some of these events have been spatially located by travel-time picking close to the actual cavern and its immediate roof. Preliminary spectral analysis of isolated microearthquakes suggests sources with non-negligible tensile components possibly related to fluid-filled cracks. Rock-debris falling into the cavern from delamination of clay marls in the immediate roof is probably another source of seismic excitation. This was later confirmed when the most important seismic swarms occurred at the site during May 2007, accompanied by the

  5. Stability of interbed for salt cavern gas storage in solution mining considering cusp displacement catastrophe theory

    Directory of Open Access Journals (Sweden)

    Le Yu

    2015-03-01

    Full Text Available Cusp displacement catastrophe theory can be introduced to propose a new method about instability failure of the interbed for gas storage cavern in bedded salt in solution mining. We can calculate initial fracture drawing pace of this interbed to obtain 2D and 3D gas storage shapes at this time. Moreover, Stability evaluation of strength reduction finite element method (FEM based on this catastrophe theory can used to evaluate this interbed stability after initial fracture. A specific example is simulated to obtain the influence of the interbed depth, cavern internal pressure, and cavern building time on stability safety factor (SSF. The results indicate: the value of SSF will be lower with the increase of cavern building time in solution mining and the increase of interbed depth and also this value remains a rise with the increase of cavern internal pressure Especially, we can conclude that the second-fracture of the interbed may take place when this pressure is lower than 6 MPa or after 6 days later of the interbed after initial fracture. According to above analysis, some effective measures, namely elevating the tube up to the top of the interbed, or changing the circulation of in-and-out lines, can be introduced to avoid the negative effects when the second-fracture of the interbed may occur.

  6. Endoscope-assisted resection of cavernous angioma at the foramen of Monro: a case report.

    Science.gov (United States)

    Matsumoto, Yuji; Kurozumi, Kazuhiko; Shimazu, Yousuke; Ichikawa, Tomotsugu; Date, Isao

    2016-01-01

    Intraventricular cavernous angiomas are rare pathological entities, and those located at the foramen of Monro are even rarer. We herein present a case of cavernous angioma at the foramen of Monro that was successfully treated by neuroendoscope-assisted surgical removal, and review the relevant literature. A 65-year-old woman had experienced headache and vomiting for 10 days before admission to another hospital. Magnetic resonance imaging (MRI) showed a mass at the foramen of Monro, and obstructive hydrocephalus of both lateral ventricles. The patient was then referred to our hospital. Neurological examination on admission to our hospital showed memory disturbance (Mini-Mental State Examination 20/30) and wide-based gait. A cavernous angioma at the foramen of Monro was diagnosed based on the typical popcorn-like appearance of the lesion on MRI. The lesion was completely removed by neuroendoscope-assisted transcortical surgery with the Viewsite Brain Access System (Vycor Medical Inc., Boca Raton, FL), leading to a reduction in the size of the ventricles. The resected mass was histologically confirmed to be cavernous angioma. The patient's symptoms resolved immediately and there were no postoperative complications. Minimally invasive neuroendoscope-assisted surgery was used to successfully treat a cavernous angioma at the foramen of Monro.

  7. Gd-DTPA in the evaluation of the normal and adnormal cavernous sinus

    International Nuclear Information System (INIS)

    Marks, M.P.; Thrush, A.; Enzmann, D.

    1989-01-01

    This paper reports on Gd-DTPA used in the evaluation of normal and abnormal cavernous sinus anatomy. Twenty-five normal subjects and 11 patients with cavernous sinus invasion were studied before Gd-DTPA enhancement. Normal studies were assessed for the conspicuity of the dural margins, the trigeminal cistern, and intracavernous and exiting cranial nerves. Contrast medium enhancement improved deductibility of the medical cavernous sinus margin (68% vs 38% on precontrast images) and intracavernous cranial nerves. Cranial nerves were inconsistently seen even on postcontrast images (cranial nerve III, 88%; v 1 , 36%, V 2 , 38%). On the abnormal images, contrast enhancement was beneficial in defining the relationship of tumor to parasellar structures, egress of tumor through bony foramina, and compression of the trigeminal cistern

  8. Isolated Trochlear Nerve Palsy Associated with Carotid–Cavernous Sinus Fistula

    Directory of Open Access Journals (Sweden)

    Chih-Ming Lin

    2009-06-01

    Full Text Available Cranial nerve ophthalmoplegia linked with a cavernous sinus lesion usually involves the third, fourth and sixth cranial nerve. Isolated fourth nerve palsy caused by carotid–cavernous sinus fistula (CCSF is rare, and related case reports are sporadic in the literature. We report a 67-year-old woman with thunderclap-type headache and isolated right-side trochlear nerve palsy. The unique history and possible pathophysiologic mechanism are discussed. We propose that: (1 thunderclap-type headache could serve as a first symptom of CCSF; and (2 isolated trochlear nerve palsy within the cavernous sinus is not unusual. First-line clinicians should be alert and more aware of this entity.

  9. The evaluation of therapeutic effect of different embolic agents embolization for hepatic cavernous hemangioma

    International Nuclear Information System (INIS)

    Wei Dingtai; Lin Shifeng; Xin Yongtong; Ye Jian'an; Chen Youying

    2007-01-01

    Objective: To evaluate the therapeutic effect of different embolic agents embolization for hepatic cav- ernous hemangioma to select an appropriate embolic agent. Methods: 16 patients with hepatic cavernous hemangioma were treated with Ivalon Ethanol lipiodol emulsion and Pingyangmycin lipiodol emulsion respectively, and observed the therapeutic effect through Ultrasound CT and MRI. Results: Hepatic cavernous hemangioma that were embolization with Ivalon have no changed or were enlarged, which were embolization with Ethanol lipiodol emulsion and Pingyangmycin lipiodol emulsion were all decreased or completely vanished. Conclusion: In embolization for hepatic cavernous hemangioma, the particulate embolic agent Ivalon has no effect, and liquid embolic agent Ethanol lipiodol emulsion and Pingyangmycin lipiodol emulsion proved to be effective. (authors)

  10. Spectacular test of the fire extinguishing system in the underground cavern of the CMS experiment

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    The enormous rumbling heard 100 m under the earth on Friday, 12 May, was not the start of a foam party at CMS. The Safety Team looked on from the second tier of the CMS underground cavern as it reechoed to the sound of water rushing through the two huge pipes overhead and the air was filled with a mixture of water and foam. A minute later it was a winter wonderland, as fluffy puffs of foam came shooting out of the twelve foam blowers lining the upper cavern walls on both sides. In less than two minutes 7 m3 of water mixed with a small percentage of foaming liquid, was transformed into 5600 m3 of foam and discharged into the cavern.

  11. Treatment and Outcome of Epileptogenic Temporal Cavernous Malformations

    Directory of Open Access Journals (Sweden)

    Yong-Zhi Shan

    2015-01-01

    Full Text Available Background: The aim of this study is to explore the treatment and outcome of epileptogenic temporal lobe cavernous malformations (CMs. Methods: We analyzed retrospectively the profiles of 52 patients diagnosed as temporal lobe CMs associated with epilepsy. Among the 52 cases, 11 underwent a direct resection of CM along with the adjacent zone of hemosiderin rim without electrocorticogram (ECoG monitoring while the other 41 cases had operations under the guidance of ECoG. Forty-six patients were treated by lesionectomy + hemosiderin rim while the other six were treated by lesionectomy + hemosiderin rim along with extended epileptogenic zone resection. The locations of lesions, the duration of illness, the manifestation, the excision ranges and the outcomes of postoperative follow-up were analyzed, respectively. Results: All of the 52 patients were treated by microsurgery. There was no neurological deficit through the long-term follow-up. Outcomes of seizure control are as follows: 42 patients (80.8% belong to Engel Class I, 5 patients (9.6% belong to Engel Class II, 3 patients (5.8% belong to Engel Class III and 2 patients (3.8% belong to Engel Class IV. Conclusion: Patients with epilepsy caused by temporal CMs should be treated as early as possible. Resection of the lesion and the surrounding hemosiderin zone is necessary. Moreover, an extended excision of epileptogenic cortex or cerebral lobes is needed to achieve a better prognosis if the ECoG indicates the existence of an extra epilepsy onset origin outside the lesion itself.

  12. Ultimate storage in salt caverns / status report; Endverwahrung von Salzkavernen / Stand der Entwicklung

    Energy Technology Data Exchange (ETDEWEB)

    Crotogino, F.; Schmidt, U. [Kavernen Bau- und Betriebs-GmbH, Hannover (Germany)

    1998-12-31

    The contribution reviews the state of knowledge on final storage in salt caverns. The long-term effects of a hermetically sealed, brine-filled cavern are discussed. So far, there are no valid predictions. (orig.) [Deutsch] In dem Beitrag wird der derzeitige Kenntnis- und Diskussionsstand zur Endverwahrung von Salzkavernen zusammengefasst. Aufbauend auf den bisher vorliegenden Vorstellungen zur Soleimpraegnation bei einem Innendruck, der nahezu dem Ueberlagerungsdruck entspricht, werden die denkbaren langfristigen Auswirkungen einer vollstaendig abgeschlossenen solegefuellten Kaverne skizziert; belastbare Prognosen sind derzeit noch nicht moeglich. (orig.)

  13. Cavernous hemangioma concurrently involving the anterior and middle mediastinum and the lung parenchyma: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jee Hyun; Lee, Soo Jung; Kim, Sung Jin; Cho, Bum Sang [Dept. of Radiology, Chungbuk National University Hospital, Cheongju (Korea, Republic of)

    2017-04-15

    Hemangioma is rarely found in the mediastinum or lung. In the mediastinum, this tumor is usually located in the anterior mediastinum and manifests as a nonspecific soft tissue mass. In the lung, it usually presents as a well-defined nodule. To the best of our knowledge, there is no case of cavernous hemangioma concurrently involving the mediastinum and lung parenchyma, except for one case of concurrent cardiac and pulmonary hemangiomas. Here, we present an interesting case of cystic anterior and middle mediastinal masses together with multiple pulmonary nodules and ground glass opacities, which were diagnosed as cavernous hemangiomas. When similar findings are encountered, clinicians should consider hemangioma in the differential diagnosis.

  14. Modeling deformation processes of salt caverns for gas storage due to fluctuating operation pressures

    Science.gov (United States)

    Böttcher, N.; Nagel, T.; Goerke, U.; Khaledi, K.; Lins, Y.; König, D.; Schanz, T.; Köhn, D.; Attia, S.; Rabbel, W.; Bauer, S.; Kolditz, O.

    2013-12-01

    In the course of the Energy Transition in Germany, the focus of the country's energy sources is shifting from fossil to renewable and sustainable energy carriers. Since renewable energy sources, such as wind and solar power, are subjected to annual, seasonal, and diurnal fluctuations, the development and extension of energy storage capacities is a priority in German R&D programs. Common methods of energy storage are the utilization of subsurface caverns as a reservoir for natural or artificial fuel gases, such as hydrogen, methane, or the storage of compressed air. The construction of caverns in salt rock is inexpensive in comparison to solid rock formations due to the possibility of solution mining. Another advantage of evaporite as a host material is the self-healing capacity of salt rock. Gas caverns are capable of short-term energy storage (hours to days), so the operating pressures inside the caverns are fluctuating periodically with a high number of cycles. This work investigates the influence of fluctuating operation pressures on the stability of the host rock of gas storage caverns utilizing numerical models. Therefore, we developed a coupled Thermo-Hydro-Mechanical (THM) model based on the finite element method utilizing the open-source software platform OpenGeoSys. Our simulations include the thermodynamic behaviour of the gas during the loading/ unloading of the cavern. This provides information on the transient pressure and temperature distribution on the cavern boundary to calculate the deformation of its geometry. Non-linear material models are used for the mechanical analysis, which describe the creep and self-healing behavior of the salt rock under fluctuating loading pressures. In order to identify the necessary material parameters, we perform experimental studies on the mechanical behaviour of salt rock under varying pressure and temperature conditions. Based on the numerical results, we further derive concepts for monitoring THM quantities in the

  15. Simulation of Mechanical Processes in Gas Storage Caverns for Short-Term Energy Storage

    Science.gov (United States)

    Böttcher, Norbert; Nagel, Thomas; Kolditz, Olaf

    2015-04-01

    In recent years, Germany's energy management has started to be transferred from fossil fuels to renewable and sustainable energy carriers. Renewable energy sources such as solar and wind power are subjected by fluctuations, thus the development and extension of energy storage capacities is a priority in German R&D programs. This work is a part of the ANGUS+ Project, funded by the federal ministry of education and research, which investigates the influence of subsurface energy storage on the underground. The utilization of subsurface salt caverns as a long-term storage reservoir for fossil fuels is a common method, since the construction of caverns in salt rock is inexpensive in comparison to solid rock formations due to solution mining. Another advantage of evaporate as host material is the self-healing behaviour of salt rock, thus the cavity can be assumed to be impermeable. In the framework of short-term energy storage (hours to days), caverns can be used as gas storage reservoirs for natural or artificial fuel gases, such as hydrogen, methane, or compressed air, where the operation pressures inside the caverns will fluctuate more frequently. This work investigates the influence of changing operation pressures at high frequencies on the stability of the host rock of gas storage caverns utilizing numerical models. Therefore, we developed a coupled Thermo-Hydro-Mechanical (THM) model based on the finite element method utilizing the open-source software platform OpenGeoSys. The salt behaviour is described by well-known constitutive material models which are capable of predicting creep, self-healing, and dilatancy processes. Our simulations include the thermodynamic behaviour of gas storage process, temperature development and distribution on the cavern boundary, the deformation of the cavern geometry, and the prediction of the dilatancy zone. Based on the numerical results, optimal operation modes can be found for individual caverns, so the risk of host rock damage

  16. Isolated sixth nerve palsy from hemorrhage of a pontine cavernous malformation.

    Science.gov (United States)

    Mallery, Robert M; Klein, Joshua P; Pless, Misha L

    2012-12-01

    A 32-year-old woman who developed binocular horizontal diplopia was found to have an isolated fascicular sixth nerve palsy secondary to hemorrhage of a cavernous malformation within the left pontine tegmentum. There was sparing of the paramedian pontine reticular formation and absence of a horizontal gaze palsy. The natural history of cavernous malformations and a mechanism by which hemorrhage of these vascular lesions may produce minimal neurologic signs, including isolated ocular motor cranial nerve palsies, is discussed. Magnetic resonance imaging (MRI) that includes susceptibility-weighted sequences leads to their accurate diagnosis.

  17. A NOVEL PROCESS TO USE SALT CAVERNS TO RECEIVE SHIP BORNE LNG

    Energy Technology Data Exchange (ETDEWEB)

    Michael M. McCall; William M. Bishop; Marcus Krekel; James F. Davis; D. Braxton Scherz

    2005-05-31

    This cooperative research project validates use of man made salt caverns to receive and store the cargoes of LNG ships in lieu of large liquid LNG tanks. Salt caverns will not tolerate direct injection of LNG because it is a cryogenic liquid, too cold for contact with salt. This research confirmed the technical processes and the economic benefits of pressuring the LNG up to dense phase, warming it to salt compatible temperatures and then directly injecting the dense phase gas into salt caverns for storage. The use of salt caverns to store natural gas sourced from LNG imports, particularly when located offshore, provides a highly secure, large scale and lower cost import facility as an alternative to tank based LNG import terminals. This design can unload a ship in the same time as unloading at a tank based terminal. The Strategic Petroleum Reserve uses man made salt caverns to securely store large quantities of crude oil. Similarly, this project describes a novel application of salt cavern gas storage technologies used for the first time in conjunction with LNG receiving. The energy industry uses man made salt caverns to store an array of gases and liquids but has never used man made salt caverns directly in the importation of LNG. This project has adapted and expanded the field of salt cavern storage technology and combined it with novel equipment and processes to accommodate LNG importation. The salt cavern based LNG receiving terminal described in the project can be located onshore or offshore, but the focus of the design and cost estimates has been on an offshore location, away from congested channels and ports. The salt cavern based terminal can provide large volumes of gas storage, high deliverability from storage, and is simplified in operation compared to tank based LNG terminals. Phase I of this project included mathematical modeling that proved a salt cavern based receiving terminal could be built at lower capital cost, and would have significantly higher

  18. Surgical management of a hemorrhagic pediatric brainstem cavernous malformation – A case report

    Directory of Open Access Journals (Sweden)

    Deborah X. Xie

    2017-06-01

    Full Text Available Vascular malformations of the central nervous system such as cavernous malformations and arteriovenous malformations are rare lesions with controversial management recommendations in the pediatric population. We report a case of a 3-year-old male who presented with multiple discrete episodes of focal neurological deficits including ataxia and an abducens nerve palsy. Imaging revealed a 1.5 cm hemorrhagic mass located in the pons that was concerning for a cavernous malformation. This lesion was completely excised via a combined transpetrosal approach, and the patient had complete resolution of neurologic symptoms at three-month follow-up.

  19. Trial Readiness in Cavernous Angiomas With Symptomatic Hemorrhage (CASH).

    Science.gov (United States)

    Polster, Sean P; Cao, Ying; Carroll, Timothy; Flemming, Kelly; Girard, Romuald; Hanley, Daniel; Hobson, Nicholas; Kim, Helen; Koenig, James; Koskimäki, Janne; Lane, Karen; Majersik, Jennifer J; McBee, Nichol; Morrison, Leslie; Shenkar, Robert; Stadnik, Agnieszka; Thompson, Richard E; Zabramski, Joseph; Zeineddine, Hussein A; Awad, Issam A

    2018-04-11

    Brain cavernous angiomas with symptomatic hemorrhage (CASH) are uncommon but exact a heavy burden of neurological disability from recurrent bleeding, for which there is no proven therapy. Candidate drugs to stabilize the CASH lesion and prevent rebleeding will ultimately require testing of safety and efficacy in multisite clinical trials. Much progress has been made in understanding the epidemiology of CASH, and novel biomarkers have been linked to the biological mechanisms and clinical activity in lesions. Yet, the ability to enroll and risk-stratify CASH subjects has never been assessed prospectively at multiple sites. Biomarkers and other outcomes have not been evaluated for their sensitivity and reliability, nor have they been harmonized across sites. To address knowledge gaps and establish a research network as infrastructure for future clinical trials, through the Trial Readiness grant mechanism, funded by National Institute of Neurological Disorders and Stroke/National Institutes of Health. This project includes an observational cohort study to assess (1) the feasibility of screening, enrollment rates, baseline disease categorization, and follow-up of CASH using common data elements at multiple sites, (2) the reliability of imaging biomarkers including quantitative susceptibility mapping and permeability measures that have been shown to correlate with lesion activity, and (3) the rates of recurrent hemorrhage and change in functional status and biomarker measurements during prospective follow-up. We propose a harmonized multisite assessment of enrollment rates of CASH, baseline features relevant to stratification in clinical trials, and follow-up assessments of functional outcomes in relation to clinical bleeds. We introduce novel biomarkers of vascular leak and hemorrhage, with firm mechanistic foundations, which have been linked to clinical disease activity. We shall test their reliability and validity at multiple sites, and assess their changes over time

  20. Derivation and application of an analytical rock displacement solution on rectangular cavern wall using the inverse mapping method.

    Directory of Open Access Journals (Sweden)

    Mingzhong Gao

    Full Text Available Rectangular caverns are increasingly used in underground engineering projects, the failure mechanism of rectangular cavern wall rock is significantly different as a result of the cross-sectional shape and variations in wall stress distributions. However, the conventional computational method always results in a long-winded computational process and multiple displacement solutions of internal rectangular wall rock. This paper uses a Laurent series complex method to obtain a mapping function expression based on complex variable function theory and conformal transformation. This method is combined with the Schwarz-Christoffel method to calculate the mapping function coefficient and to determine the rectangular cavern wall rock deformation. With regard to the inverse mapping concept, the mapping relation between the polar coordinate system within plane ς and a corresponding unique plane coordinate point inside the cavern wall rock is discussed. The disadvantage of multiple solutions when mapping from the plane to the polar coordinate system is addressed. This theoretical formula is used to calculate wall rock boundary deformation and displacement field nephograms inside the wall rock for a given cavern height and width. A comparison with ANSYS numerical software results suggests that the theoretical solution and numerical solution exhibit identical trends, thereby demonstrating the method's validity. This method greatly improves the computing accuracy and reduces the difficulty in solving for cavern boundary and internal wall rock displacements. The proposed method provides a theoretical guide for controlling cavern wall rock deformation failure.

  1. Physical and Numerical Modeling of the Stability of Deep Caverns in Tahe Oil Field in China

    Directory of Open Access Journals (Sweden)

    Chao Wang

    2017-06-01

    Full Text Available Cave collapses emerge during the process of oil reservoir development, seriously affecting oil production. To reveal the collapse and failure mechanism of the carbonate cavern with a buried depth of 5600 m in Tahe Oil Field, using a self-developed ultra-high pressure model test system with the intelligent numerical control function, the model simulation material of carbonate rocks developed to carry out the 3D geo-mechanical model test. The model test and numerical results indicate that: (1 collapse and failure mechanism of the deep-buried caves mainly involve the failure mode of tensile shear. The rupture plane on the side wall is approximately parallel to the direction of maximum principal compressive stress. The V-type tension and split rupture plane then emerges. (2 In the process of forming holes in the model caverns, micro cracks are generated at the foot of the left and right side walls of the caverns, and the roof panels are constantly moving downward. The shorter the distance to the cave wall, the severer the destructiveness of the surrounding rocks will be. (3 The displacement of the top of the model cavern is relatively large and uniform, indicating that the cave roof moves downward as a whole. The area of the cavity suffering damage is 2.3 times as large as the cave span. The research results in this paper lay a solid test basis for revealing the cave collapse and failure mechanism in super depth.

  2. Wegener's granulomatosis with unusual cavernous sinus and sella turcica extension

    Energy Technology Data Exchange (ETDEWEB)

    Hermann, M.; Bobek-Billewicz, B. [Dept. of Radiology, Medical University of Gdansk (Poland); Bullo, B.; Hermann, A.; Rutkowski, B. [Dept. of Nephrology, Medical University of Gdansk (Poland)

    1999-07-01

    Intracerebral extension of Wegener's granulomatosis (WG) is rare. We present a patient with oculomotor and trochlear nerve palsy with histologically proved WG. An MR examination revealed granulomatous tissue in nasal cavity, paranasal sinuses with meningeal infiltration, and uncommon penetration into cavernous sinus and sella turcica. The MR images before and during pharmacological therapy are presented. (orig.)

  3. Aggressive cavernous sinus dural arteriovenous fistula: Angioarchitecture analysis and embolization by various approaches

    Directory of Open Access Journals (Sweden)

    Chao-Bao Luo

    2016-03-01

    Conclusion: Aggressive CSDAVFs are associated with occlusion/stenosis of the IPS or compartment of IPS–cavernous sinus with leptomeningeal reflux. In this limited case series, aggressive CSDAVFs most presented with brainstem ischemia, followed by nonhemorrhagic/hemorrhagic stroke in the cerebrum. Embolization through various access routes is a feasible method to manage these aggressive CSDAVFs, with an acceptable level of periprocedural risks.

  4. Spall formation in solution mined storage caverns based on a creep and fracture analysis

    International Nuclear Information System (INIS)

    Munson, Darrell E.

    2000-01-01

    Because of limited direct observation, understanding of the interior conditions of the massive storage caverns constructed in Gulf Coast salt domes is realizable only through predictions of salt response. Determination of the potential for formation of salt spans, leading to eventual salt falls, is based on salt creep and fracture using the Multimechanism-Deformation Coupled Fracture (MCDF) model. This is a continuum model for creep, coupled to continuum damage evolution. The model has been successfully tested against underground results of damage around several test rooms at the Waste Isolation Pilot Plant (WIPP). Model simulations, here, evaluate observations made in the Strategic Petroleum Reserve (SPR) storage caverns, namely, the accumulation of material on cavern floors and evidence of salt falls. A simulation of a smooth cavern wall indicates damage is maximum at the surface but diminishes monotonically into the salt, which suggests the source of salt accumulation is surface sluffing. If a protuberance occurs on the wall, fracture damage can form beneath the protuberance, which will eventually cause fracture, and lead to a salt fall

  5. Antioxidative mechanism of Lycium barbarum polysaccharides promotes repair and regeneration following cavernous nerve injury

    Directory of Open Access Journals (Sweden)

    Zhan-kui Zhao

    2016-01-01

    Full Text Available Polysaccharides extracted from Lycium barbarum exhibit antioxidant properties. We hypothesized that these polysaccharides resist oxidative stress-induced neuronal damage following cavernous nerve injury. In this study, rat models were intragastrically administered Lycium barbarum polysaccharides for 2 weeks at 1, 7, and 14 days after cavernous nerve injury. Serum superoxide dismutase and glutathione peroxidase activities significantly increased at 1 and 2 weeks post-injury. Serum malondialdehyde levels decreased at 2 and 4 weeks. At 12 weeks, peak intracavernous pressure, the number of myelinated axons and nicotinamide adenine dinucleotide phosphate-diaphorase-positive nerve fibers, levels of phospho-endothelial nitric oxide synthase protein and 3-nitrotyrosine were higher in rats administered at 1 day post-injury compared with rats administered at 7 and 14 days post-injury. These findings suggest that application of Lycium barbarum polysaccharides following cavernous nerve crush injury effectively promotes nerve regeneration and erectile functional recovery. This neuroregenerative effect was most effective in rats orally administered Lycium barbarum polysaccharides at 1 day after cavernous nerve crush injury.

  6. Preliminary Technical and Legal Evaluation of Disposing of Nonhazardous Oil Field Waste into Salt Caverns

    Energy Technology Data Exchange (ETDEWEB)

    Ayers, Robert C.; Caudle, Dan; Elcock, Deborah; Raivel, Mary; Veil, John; and Grunewald, Ben

    1999-01-21

    This report presents an initial evaluation of the suitability, feasibility, and legality of using salt caverns for disposal of nonhazardous oil field wastes. Given the preliminary and general nature of this report, we recognize that some of our findings and conclusions maybe speculative and subject to change upon further research on this topic.

  7. Cavernous sinus apoplexy presenting isolated sixth cranial nerve palsy: case report.

    Science.gov (United States)

    Zoli, Matteo; Mazzatenta, Diego; Pasquini, Ernesto; Ambrosetto, Paolo; Frank, Giorgio

    2012-12-01

    The clinical and radiological findings of a patient affected by apoplexy of an adenoma located within cavernous sinus and presenting isolated Cranial Nerve (CN) VI palsy are reported. The differential diagnosis with other pathologies is debated, and pathogenesis of isolated abducens nerve palsy is investigated. The pertinent literature of this uncommon case of apoplexy is reviewed. A 59-year-old female presented sudden appearance of CN VI palsy associated to violent headache. Endocrinological assessment did not show pituitary insufficiency; MRI depicted an adenoma located within the left CS. She underwent an endoscopic endonasal procedure with extensive opening of the cavernous sinus, occupied by an ischemic adenoma. Afterward, neurological symptoms promptly resolved and the patient was discharged after 5 days. At 3 months follow-up MRI radical tumor removal was assessed, and the patient resulted neurologically intact. The review of the pertinent literature shows that apoplexy of pituitary tumor exclusively located within the Cavernous Sinus is a very uncommon event. The distinctive clinical presentation is represented by the sudden abducens nerve palsy and the absence of pituitary insufficiency and it could be explained by the vulnerability of the nerve along its course within the cavernous sinus, and by the sparing of the sellar content by the adenoma.

  8. Large cavernous hemangioma of the adrenal gland: Laparoscopic treatment. Report of a case

    Directory of Open Access Journals (Sweden)

    A. Agrusa

    2015-01-01

    Conclusion: Laparoscopic adrenalectomy is considered the standard treatment in case of diagnosis of benign lesions. In this case report we discussed a large adrenal cavernous hemangioma treated with laparoscopic approach. Fundamental is the study of preoperative endocrine disorders and radiologic findings to exclude signs of malignancy.

  9. Arteriovenous Malformation in Temporal Lobe Presenting as Contralateral Ocular Symptoms Mimicking Carotid-Cavernous Fistula

    Directory of Open Access Journals (Sweden)

    Fadzillah Mohd-Tahir

    2013-01-01

    Full Text Available Aim. To report a rare case of arteriovenous malformation in temporal lobe presenting as contralateral orbital symptoms mimicking carotid-cavernous fistula. Method. Interventional case report. Results. A 31-year-old Malay gentleman presented with 2-month history of painful progressive exophthalmos of his left eye associated with recurrent headache, diplopia, and reduced vision. Ocular examination revealed congestive nonpulsating 7 mm exophthalmos of the left eye with no restriction of movements in all direction. There was diplopia in left lateral gaze. Left IOP was elevated at 29 mmHg. Left eye retinal vessels were slightly dilated and tortuous. CT scan was performed and showed right temporal arteriovenous malformation with a nidus of 3.8 cm × 2.5 cm with right middle cerebral artery as feeding artery. There was dilated left superior ophthalmic vein of 0.9 mm in diameter with enlarged left cavernous sinus. MRA and carotid angiogram confirmed right temporal arteriovenous malformation with no carotid-cavernous fistula. Most of the intracranial drainage was via left cavernous sinus. His signs and symptoms dramatically improved following successful embolisation, completely resolved after one year. Conclusion. Intracranial arteriovenous malformation is rarely presented with primary ocular presentation. Early intervention would salvage the eyes and prevent patients from more disaster morbidity or fatality commonly due to intracranial haemorrhage.

  10. Neurturin enhances the recovery of erectile function following bilateral cavernous nerve crush injury in the rat

    Directory of Open Access Journals (Sweden)

    Klein Robert D

    2007-03-01

    Full Text Available Abstract Background The molecular mechanisms responsible for the survival and preservation of function for adult parasympathetic ganglion neurons following injury remain incompletely understood. However, advances in the neurobiology of growth factors, neural development, and prevention of cell death have led to a surge of clinical interest for protective and regenerative neuromodulatory strategies, as surgical therapies for prostate, bladder, and colorectal cancers often result in neuronal axotomy and debilitating loss of sexual function or continence. In vitro studies have identified neurturin, a glial cell line-derived neurotrophic factor, as a neuromodulator for pelvic cholinergic neurons. We present the first in vivo report of the effects of neurturin upon the recovery of erectile function following bilateral cavernous nerve crush injury in the rat. Methods In these experiments, groups (n = 8 each consisted of uninjured controls and animals treated with injection of albumin (blinded crush control group, extended release neurotrophin-4 or neurturin to the site of cavernous nerve crush injury (100 μg per animal. After 5 weeks, recovery of erectile function (treatment effect was assessed by cavernous nerve electrostimulation and peak aortic pressures were measured. Investigators were unblinded to specific treatments after statistical analyses were completed. Results Erectile dysfunction was not observed in the sham group (mean maximal intracavernous pressure [ICP] increase of 117.5 ± 7.3 cmH2O, whereas nerve injury and albumin treatment (control produced a significant reduction in ICP elevation of 40.0 ± 6.3 cmH2O. Neurturin facilitated the preservation of erectile function, with an ICP increase of 55% at 62.0 ± 9.2 cmH2O (p Conclusion Treatment with neurturin at the site of cavernous nerve crush injury facilitates recovery of erectile function. Results support further investigation of neurturin as a neuroprotective and/or neuroregenerative

  11. Intelligent Autofeedback and Safety Early-Warning for Underground Cavern Engineering during Construction Based on BP Neural Network and FEM

    Directory of Open Access Journals (Sweden)

    Lei Xu

    2015-01-01

    Full Text Available The low efficiency of feedback analysis is one of the main shortcomings in the construction of underground cavern engineering. With this in mind, a method of intelligent autofeedback and safety early-warning for underground cavern is proposed based on BP neural network and FEM. The training sample points are chosen by using uniform test design method, and the autogeneration of FEM calculation file for ABAQUS is realized by using the technique of file partition, information grouping, and orderly numbering. Then, intelligent autoinversion of mechanics parameters is realized, and the automatic connection of parameter inversion, subsequent prediction, and safety early-warning is achieved. The software of intelligent autofeedback and safety early-warning for underground cavern engineering during construction is developed. Finally, the applicability of the proposed method and the developed software is verified through an application example of underground cavern of a pumped-storage power station located in Southwest China.

  12. Cavernous Hemangioma of the Orbit and Its Impact on Orbital Fat

    Directory of Open Access Journals (Sweden)

    O. Yu. Yatsenko

    2017-01-01

    Full Text Available The most common representative of primary tumors is a cavernous hemangioma of the orbit, which can lead to the disorder of functions of an eye and a cosmetic defect. The literature has repeatedly described the clinical picture of patients with cavernous hemangioma, their CT semiotics, hemangiomasintercourse with orbital structures. However, there is no data about the effect of the tumor on the state of the orbital fat.The purpose — to study structural features of cavernous hemangiomaand toundertake a study of state of the orbital fat, depending on the size of tumors.Patients and methods. We studied 36 patients with cavernous hemangioma of the orbit. CT scans were performed according to standard procedures to give axial and frontal slices. Volumetric soft tissues of the orbit indicators obtained after the construction of three-dimensional models. Originally built a three-dimensional reconstruction of the osseous orbit outside the orbit's part of the eye, and then — a muscular channel and soft tissue reconstruction unit (extraocular muscles, the optic nerve, lacrimal gland and eyes. We calculate the orbit of the eye and orbital fat. The volume of the orbital part of the eye obtained by subtracting the volume of the volume of its eyes outside the orbit’s part. The amount of fiber internal surgical space obtained by subtracting from the muscular channel volume of extraocular muscles and optic nerve. Control in all cases was a healthy contralateral orbit.Results and discussion. It was found that an increase in the volume of tumors occurssubatrophy of orbital fat. In patients with smallhemangiomas the amount of orbital fat is reduced by about 0.5 cm3, in patients with an average hemangiomasthe amount of orbital fat is retracted more than 1 cm3. The most prominent orbital fat atrophy in theorbitlocalization of large cavernous hemangiomas (on 2,88±0.09 cm3.Conclusions. An increase in the size of cavernous hemangioma leading to its structural

  13. Commercial potential of natural gas storage in lined rock caverns (LRC)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    The geologic conditions in many regions of the United States will not permit the development of economical high-deliverability gas storage in salt caverns. These regions include the entire Eastern Seaboard; several northern states, notably Minnesota and Wisconsin; many of the Rocky Mountain States; and most of the Pacific Northwest. In late 1997, the United States Department of Energy (USDOE) Federal Energy Technology Center engaged Sofregaz US to investigate the commercialization potential of natural gas storage in Lined Rock Caverns (LRC). Sofregaz US teamed with Gaz de France and Sydkraft, who had formed a consortium, called LRC, to perform the study for the USDOE. Underground storage of natural gas is generally achieved in depleted oil and gas fields, aquifers, and solution-mined salt caverns. These storage technologies require specific geologic conditions. Unlined rock caverns have been used for decades to store hydrocarbons - mostly liquids such as crude oil, butane, and propane. The maximum operating pressure in unlined rock caverns is limited, since the host rock is never entirely impervious. The LRC technology allows a significant increase in the maximum operating pressure over the unlined storage cavern concept, since the gas in storage is completely contained with an impervious liner. The LRC technology has been under development in Sweden by Sydkraft since 1987. The development process has included extensive technical studies, laboratory testing, field tests, and most recently includes a storage facility being constructed in southern Sweden (Skallen). The LRC development effort has shown that the concept is technically and economically viable. The Skallen storage facility will have a rock cover of 115 meters (375 feet), a storage volume of 40,000 cubic meters (250,000 petroleum barrels), and a maximum operating pressure of 20 MPa (2,900 psi). There is a potential for commercialization of the LRC technology in the United States. Two regions were studied

  14. Intelligent Autofeedback and Safety Early-Warning for Underground Cavern Engineering during Construction Based on BP Neural Network and FEM

    OpenAIRE

    Xu, Lei; Zhang, Taijun; Ren, Qingwen

    2015-01-01

    The low efficiency of feedback analysis is one of the main shortcomings in the construction of underground cavern engineering. With this in mind, a method of intelligent autofeedback and safety early-warning for underground cavern is proposed based on BP neural network and FEM. The training sample points are chosen by using uniform test design method, and the autogeneration of FEM calculation file for ABAQUS is realized by using the technique of file partition, information grouping, and order...

  15. Rates and characteristics of radiographically detected intracerebral cavernous malformations after cranial radiation therapy in pediatric cancer patients.

    Science.gov (United States)

    Gastelum, Erica; Sear, Katherine; Hills, Nancy; Roddy, Erika; Randazzo, Dominica; Chettout, Nassim; Hess, Christopher; Cotter, Jennifer; Haas-Kogan, Daphne A; Fullerton, Heather; Mueller, Sabine

    2015-06-01

    Rates and characteristics of intracerebral cavernous malformations after cranial radiation therapy remain poorly understood. Herein we report on intracerebral cavernous malformations detected on follow-up imaging in pediatric cancer patients who received cranial radiation therapy at age ≤18 years from 1980 to 2009. Through chart reviews (n = 362) and phone interviews (n = 104) of a retrospective cohort, we identified 10 patients with intracerebral cavernous malformations. The median latency time for detection of intracerebral cavernous malformations after cranial radiation therapy was 12 years (range 1-24 years) at a median age of 21.4 years (interquartile range = 15-28). The cumulative incidence was 3% (95% confidence interval 1%-8%) at 10 years post cranial radiation therapy and 14% (95% confidence interval 7%-26%) at 15 years. Three patients underwent surgical resection. Two surgical specimens were pathologically similar to sporadically occurring intracerebral cavernous malformations; one was consistent with capillary telangiectasia. Intracerebral cavernous malformations are common after cranial radiation therapy and can show a spectrum of histologic features. © The Author(s) 2014.

  16. Virtual Reality Model of the Three-Dimensional Anatomy of the Cavernous Sinus Based on a Cadaveric Image and Dissection.

    Science.gov (United States)

    Qian, Zeng-Hui; Feng, Xu; Li, Yang; Tang, Ke

    2018-01-01

    Studying the three-dimensional (3D) anatomy of the cavernous sinus is essential for treating lesions in this region with skull base surgeries. Cadaver dissection is a conventional method that has insurmountable flaws with regard to understanding spatial anatomy. The authors' research aimed to build an image model of the cavernous sinus region in a virtual reality system to precisely, individually and objectively elucidate the complete and local stereo-anatomy. Computed tomography and magnetic resonance imaging scans were performed on 5 adult cadaver heads. Latex mixed with contrast agent was injected into the arterial system and then into the venous system. Computed tomography scans were performed again following the 2 injections. Magnetic resonance imaging scans were performed again after the cranial nerves were exposed. Image data were input into a virtual reality system to establish a model of the cavernous sinus. Observation results of the image models were compared with those of the cadaver heads. Visualization of the cavernous sinus region models built using the virtual reality system was good for all the cadavers. High resolutions were achieved for the images of different tissues. The observed results were consistent with those of the cadaver head. The spatial architecture and modality of the cavernous sinus were clearly displayed in the 3D model by rotating the model and conveniently changing its transparency. A 3D virtual reality model of the cavernous sinus region is helpful for globally and objectively understanding anatomy. The observation procedure was accurate, convenient, noninvasive, and time and specimen saving.

  17. Are bilateral cavernous hemangiomas of the orbit rare entities? The role of MRI in a retrospective study

    Energy Technology Data Exchange (ETDEWEB)

    Paonessa, Amalia [Department of Neuroradiology, S.Salvatore Hospital, University of L' Aquila, L' Aquila (Italy)], E-mail: apaonessa7@hotmail.com; Limbucci, Nicola; Gallucci, Massimo [Department of Neuroradiology, S.Salvatore Hospital, University of L' Aquila, L' Aquila (Italy)

    2008-05-15

    Cavernous hemangioma is a benign orbital extraocular vascular lesion consisting of large dilated venous channels with fibrous, well-delineated capsule and hemosiderin deposition. Cavernous hemangioma is considered to be almost always unilateral and bilateral cases have been rarely described. The aim of our study is to evaluate imaging characteristics of cavernous hemangioma and evaluate the prevalence of bilateral cases. We studied 14 patients with cavernous hemangioma of the orbit with surgical confirmation. MRI was performed on a 1.5-T unit before and after contrast agent administration. Each MR examination had been retrospectively evaluated in order to define signal patterns, dimensions, location and other main imaging characteristics. In 3 out of the 14 cases studied (21.4%) bilateral cavernous hemangiomas were found. Thirteen masses appeared isointense on T1, two were hypointense, and two heterogeneous. On T2, 12 were hyperintense, 3 were heterogeneous, 1 isointense, and 1 hypointense. Contrast enhancement was inhomogeneous in 5, homogeneous and intense in 12 cases. The size ranged from 3 mm up to 21 mm (average 14.57). In four patients also CT scan without contrast administration of the orbits was performed. Bilateral cavernous hemangioma appears to be more frequent than as predicted by the literature. In our opinion the main reason of this incongruence is related to technological advances. Our results could also be related to carelessness of radiologists to inspect the other orbit for possible concomitant lesions, and thus invites to major attention in exploring both orbits for eventual bilateral lesions.

  18. 27 Febuary 2012 - US DoE Associate Director of Science for High Energy Physics J. Siegrist visiting the LHC superconducting magnet test hall with adviser J.-P. Koutchouk and engineer M. Bajko; in CMS experimental cavern with Spokesperson J. Incadela;in ATLAS experimental cavern with Deputy Spokesperson A. Lankford; in ALICE experimental cavern with Spokesperson P. Giubellino; signing the guest book with Director for Accelerators and Technology S. Myers.

    CERN Multimedia

    Laurent Egli

    2012-01-01

    27 Febuary 2012 - US DoE Associate Director of Science for High Energy Physics J. Siegrist visiting the LHC superconducting magnet test hall with adviser J.-P. Koutchouk and engineer M. Bajko; in CMS experimental cavern with Spokesperson J. Incadela;in ATLAS experimental cavern with Deputy Spokesperson A. Lankford; in ALICE experimental cavern with Spokesperson P. Giubellino; signing the guest book with Director for Accelerators and Technology S. Myers.

  19. Design and construction of the tensioned ties for UX15 cavern vault

    CERN Document Server

    Parkin, R J H

    2002-01-01

    Due to the programme constraints for the UX15 cavern set by CERN, it has been necessary to complete the concrete lining of the vault prior to the excavation of the bench. The vault lining is therefore being temporarily suspended from a number of pre-tensioned high capacity multi-strand tensioned ties. During excavation of the bench, additional loads will be imposed onto the vault lining due to ground displacements. In order to minimise the number of ties, the previously completed linings of the PX14 and PX16 access shafts will be used to support some of the load. Three-dimensional modelling has been undertaken to design the structures and determine the expected behaviour of this complex support system. Geotechnical instrumentation has been installed in the concrete linings and the ground to monitor loads and displacements during construction. After the cavern walls have been completed, the ties will be released.

  20. Design of a novel Cherenkov detectors system for machine induced background monitoring in the CMS cavern

    CERN Document Server

    Orfanelli, Styliani; Giunta, Marina; Stickland, David P; Ambrose, Mitchell J; Rusack, Roger; Finkel, Alexey

    2013-01-01

    A novel detector system has been designed for an efficient online measurement of the machineinduced background in the CMS experimental cavern. The suppression of the CMS cavern background originating from pp collision products and the 25 ns bunch spacing have set the requirements for the detector design. Each detector unit will be a radiation hard, cylindrical Cherenkov radiator optically coupled to an ultra-fast UV-sensitive photomultiplier tube, providing a prompt, directionally sensitive measurement. Simulation and test beam measurements have shown the achievability of the goals that have driven the baseline design. The system will consist of 20 azimuthally distributed detectors per end, installed at a radius of r ~ 180 cm and a distance 20.6 m away from the CMS interaction region. The detector units will enable a measurement of the transverse distribution of the bunchby- bunch machine induced background flux. This will provide important feedback from the CMS on the beam conditions during the LHC machine s...

  1. Cavernous sinus thrombophlebitis related to dental infection--two case reports.

    Science.gov (United States)

    Okamoto, Hiroaki; Ogata, Atsushi; Kosugi, Masafumi; Takashima, Hiroshi; Sakata, Shuji; Matsushima, Toshio

    2012-01-01

    Two cases of cavernous sinus thrombophlebitis (CST) caused by dental infection are described. A 64-year-old woman presented with palsies of the left oculomotor and trochlear nerves after tooth extraction for dental caries in the left maxilla. A 54-year-old man presented with palsy of the left trochlear nerve, sensory disturbance in the ophthalmic and maxillary divisions of the left trigeminal nerve, ptosis, proptosis, and chemosis after dental treatment for caries and periodontitis in the left maxilla. In both patients, computed tomography and magnetic resonance imaging with contrast medium showed non-enhanced lesions within the left cavernous sinus and dilation of the superior ophthalmic veins, which indicated CST. These conditions were resolved by administration of broad-spectrum antibiotics. CST is rare but lethal, so prompt diagnosis is crucial, and immediate appropriate treatment is essential.

  2. A rare case of abnormal uterine bleeding caused by cavernous hemangioma: a case report

    Directory of Open Access Journals (Sweden)

    Telesinghe PU

    2010-05-01

    Full Text Available Abstract Introduction Cavernous hemangiomas of the uterus are extremely rare, benign lesions. A survey of the current literature identified fewer than 50 cases of hemangioma of the uterus. Case presentation We report a case of cavernous hemangioma of the uterus in a 27-year-old Malay, para 1 woman who presented at our hospital with torrential vaginal bleeding having been transferred by land ambulance from a district hospital 30 minutes away. 11 weeks previously she had an urgent cesarean section at our hospital. She had to undergo a hysterectomy to control her bleeding after other measures were unsuccessful. A histopathological report confirmed a diffuse ramifying hemangioma of the cervix and uterus with left hematosalpinx. Conclusion Most ramifying hemangioma lesions are asymptomatic and are found incidentally, but sometimes they may cause abnormal vaginal bleeding and hence should be included in the differential diagnosis of patients with vaginal bleeding. Hysterectomy is the primary mode of treatment in most symptomatic cases.

  3. A rare case of abnormal uterine bleeding caused by cavernous hemangioma: a case report.

    Science.gov (United States)

    Benjamin, Mridula A; Yaakub, Hjh Roselina; Telesinghe, Pu; Kafeel, Gazala

    2010-05-17

    Cavernous hemangiomas of the uterus are extremely rare, benign lesions. A survey of the current literature identified fewer than 50 cases of hemangioma of the uterus. We report a case of cavernous hemangioma of the uterus in a 27-year-old Malay, para 1 woman who presented at our hospital with torrential vaginal bleeding having been transferred by land ambulance from a district hospital 30 minutes away. 11 weeks previously she had an urgent cesarean section at our hospital. She had to undergo a hysterectomy to control her bleeding after other measures were unsuccessful. A histopathological report confirmed a diffuse ramifying hemangioma of the cervix and uterus with left hematosalpinx. Most ramifying hemangioma lesions are asymptomatic and are found incidentally, but sometimes they may cause abnormal vaginal bleeding and hence should be included in the differential diagnosis of patients with vaginal bleeding. Hysterectomy is the primary mode of treatment in most symptomatic cases.

  4. Successful resection of the recurrence of a cavernous malformation of the optic chiasm

    Directory of Open Access Journals (Sweden)

    Martin Scholz

    2008-11-01

    Full Text Available Martin Scholz, Albrecht Harders, Sebastian Lücke, Ioannis Pechlivanis, Martin Engelhardt, Kirsten SchmiederDepartment of Neurosurgery, Ruhr-University Bochum, Knappschaftskrankenhaus, GermanyAbstract: The case of a 33-year-old female who suffered from a recurrence of an intrachiasmatic cavernous malformation is presented. She had already undergone surgery in 1991 and 2001 and was admitted to our hospital with reduced vision in the right eye. After MRI, and diagnosis of recurrence of the cavernoma, a neurosurgical operation was performed using the pterional approach. The intraoperative situation was documented with micro photographs. The postoperative course was uneventful. The female described a minimal improvement of her vision. No postoperative complications were observed. To our knowledge, microsurgically complete extirpation of a recurrence of an intrachiasmatic cavernoma has not yet been reported in the literature.Keywords: optic chiasm, pterional approach, cavernous malformation

  5. Magnetic resonance imaging of a cerebral cavernous haemangioma in a dog : clinical communication

    Directory of Open Access Journals (Sweden)

    J.P. Schoeman

    2002-07-01

    Full Text Available A 13-month-old, neutered, male Golden retriever presented with seizures and progressive depression. Clinical and neurological assessment was consistent with severe intracranial disease. The neurological condition progressively deteriorated and magnetic resonance imaging (MRI revealed the presence of a large, contrast-enhancing, space-occupying mass in the right cerebral hemisphere. Therapy with corticosteroids, mannitol and furosemide ameliorated the signs of depression and ataxia, but the owner elected euthanasia after 1 week. Post mortem examination of the brain confirmed the presence of a large haemorrhagic lesion in the right olfactory lobe, the histopathological appearance of which was consistent with cerebral cavernous haemangioma. This is the 1st case describing the MRI appearance of a cavernous haemangioma of the cerebrum in the veterinary literature.

  6. Delayed massive epistaxis from traumatic cavernous carotid false aneurysms: A report of two unusual cases.

    Science.gov (United States)

    Mankahla, Ncedile; LeFeuvre, David; Taylor, Allan

    2017-08-01

    Introduction Blunt head trauma can injure the cavernous segment of the internal carotid artery (ICA). This may result in a carotid cavernous fistula (CCF). Rarely, a traumatic aneurysm may bleed medially causing massive epistaxis. Case presentation We present two cases of traumatic intracavernous carotid pseudoaneurysms with delayed massive epistaxis. The patients were managed with endovascular treatment involving coil embolization with parent vessel sparing and detachable balloon occlusion with carotid sacrifice. Early clinical outcome was good in both patients. Wherever possible, the CARE 1 guidelines were followed in the reporting. Conclusion These cases illustrate the delayed nature of traumatic aneurysms and the need for a high index of suspicion in the presence of skull base fractures. The use of endovascular detachable balloon occlusion and coil embolization treatment with parent vessel preservation is shown.

  7. Prevalence of cerebral cavernous malformations associated with developmental venous anomalies increases with age.

    Science.gov (United States)

    Brinjikji, Waleed; El-Masri, Ali El-Rida; Wald, John T; Flemming, Kelly D; Lanzino, Giuseppe

    2017-09-01

    To test the hypothesis that the prevalence of cerebral cavernous malformation (CCM) associated with developmental venous anomalies (DVAs) increases with age, we studied the age-related prevalence of DVA-associated CCM among patients with DVAs. Patients with DVAs on contrast-enhanced MRI exams performed over a 2-year period were included in this study. A single neuroradiologist reviewed all imaging exams for the presence of CCMs. Baseline demographic data collected included age, gender, presence of CNS neoplasm, history of cranial radiation, and history of seizure. Patients were divided into age groups based on decade of life. Cochran-Armitage trend tests were performed to determine if increasing age was associated with CCM prevalence. A total of 1689 patients with DVAs identified on contrast-enhanced MRI were included. Of these patients, 116 (6.9%) had a cavernous malformation associated with the DVA. There was a significant positive association between age and the prevalence of DVA-associated CCM (P = 0.002). The prevalence of DVA-associated CCM was 0.8% for the 0-10 age group, 1.6% for the 11-20 age group, 7.5% for the 21-30 age group, 9.5% for the 31-40 age group, 6.1% for the 41-50 age group, 6.3% for the 51-60 age group, 7.4% for the 61-70 age group, and 11.6% for the >70 age group (P DVA-associated cavernous malformations among patients with DVAs. These findings suggest that DVA-associated cavernous malformations are acquired lesions.

  8. When nearing the ATLAS cavern UX15 through RB16: the TX1S shielding

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Photo 01: 52 tons of ATLAS TX1S shielding with bare hands. Photos 02,03,04: Installation of the second TX1S shielding tube at Point Photos 05,06: Positioning of TX1S shielding, the first ATLAS/LHC interface component to be installed underground. Photo 07: Final adjustment of the TX1S shielding tube at the interface between the LHC tunnel and the ATLAS cavern (UX15).

  9. A cavernous haemangioma of breast in male: radiological-pathological correlation

    International Nuclear Information System (INIS)

    Carreira, C.; Romero, C.; Urbasos, M.; Pinto, J.; Rodriguez, R.; Francisco, J.M. de

    2001-01-01

    Vascular tumours of the breast are especially rare in men, and a majority of them are angiosarcomas. In fact, we found only four cases of haemangioma in males in the literature. We present a case of cavernous haemangioma in a male aged 48 years, and which commenced as a palpable mass. We performed differential diagnosis and radiological-pathological correlation. We established the correct classification of this case histologically, and decided on the definitive therapeutic approach. (orig.)

  10. Serial MRI of a mycotic aneurysm of the cavernous carotid artery

    Energy Technology Data Exchange (ETDEWEB)

    Cloud, G.C.; Markus, H.S. [Division of Clinical Neuroscience, St George' s Hospital Medical School, Cranmer Terrace, London SW17 0RE (United Kingdom); Rich, P.M. [Department of Neuroradiology, Atkinson Morley' s Hospital, Copse Hill, London SW20 0NE (United Kingdom)

    2003-08-01

    Cerebral mycotic or infective aneurysms are a rare complication of infectious illness, and such aneurysms of the intracavernous portion of the internal carotid artery are rare. They have been described as a consequence of cavernous sinus infection in an immunocompromised host, but not previously in a renal transplant recipient. We present such a case with serial MRI showing progression from arterial narrowing to aneurysm formation. Transcranial Doppler sonography of the middle cerebral artery showed distal asymptomatic embolisation from the aneurysm. (orig.)

  11. Computer-aided evaluation of waste disposal cavern construction methods. ISBN 3-9801713-0-2.

    International Nuclear Information System (INIS)

    Knissel, W.; Fahlbusch, M.

    1991-01-01

    The disposal of hazardous radioactive and toxic wastes in deep geological formations is considered the safest solution in many countries. The Federal Republic of Germany prefers salt formations for underground disposal on account of the special advantages of the rock salt. Calculation methods are presented for the mathematical description of mining techniques for the construction of waste disposal salt caverns. The developed calculation model allows one to evaluate different construction methods with regard to expenses and time. (orig./DG) [de

  12. Cavernous sinus thrombosis following dental extraction: a rare case report and forgotten entity

    OpenAIRE

    Aggarwal, Karun; Rastogi, Sanjay; Joshi, Atul; Kumar, Ashish; Chaurasia, Archana; Prakash, Rajat

    2017-01-01

    Prior to the advent of efficacious antimicrobial agents, the mortality rate from cavernous sinus thrombosis (CST) was effectively 100%. There have been very few reports of CST associated with tooth extraction. A 40-year-old female presented to the emergency room with swelling over the right side of the face and history of extraction in the upper right region by an unregistered dental practitioner. The patient presented with diplopia, periorbital ecchymosis, and chemosis of the right eye. A co...

  13. A numerical study on the structural behavior of underground rock caverns for radioactive waste disposal

    International Nuclear Information System (INIS)

    Kim, Sun Hoon; Choi, Kyu Sup; Lee, Kyung Jin; Kim, Dae Hong

    1991-01-01

    In order to design safe and economical underground disposal structures for radioactive wastes, understanding the behavior of discontinuous rock masses is essential. This study includes discussions about the computational model for discontinuous rock masses and the structural analysis method for underground storage structures. Then, based on an engineering judgement a suitable selection and slight modifications on computational models and analysis methods have been made in order to analyze and understand the structural behavior of the rock cavern with discontinuities

  14. First DT+RPC chambers installation round in the UX5 cavern

    CERN Multimedia

    Jesus Puerta-Pelayo

    2007-01-01

    DT+RPC packages corresponding to sectors 1 and 7 of the barrel region cannot be installed on surface, since the lowering gantry from SX5 to UX5 uses their gaps to hold the wheels. Therefore this installation has to be carried out in the cavern. These pictures illustrate the first installation round on YB+2 right after the lowering. A total of 8 chambers were successfully installed in 2 days.

  15. Phenotypic modulation of corpus cavernosum smooth muscle cells in a rat model of cavernous neurectomy.

    Directory of Open Access Journals (Sweden)

    Fan Yang

    Full Text Available Patients undergoing radical prostatectomy (RP are at high risk for erectile dysfunction (ED due to potential cavernous nerve (CN damage during surgery. Penile hypoxia after RP is thought to significantly contribute to ED pathogenesis.We previously showed that corpora cavernosum smooth muscle cells (CCSMCs undergo phenotypic modulation under hypoxic conditions in vitro. Here, we studied such changes in an in vivo post-RP ED model by investigating CCSMCs in bilateral cavernous neurectomy (BCN rats.Sprague-Dawley rats underwent sham (n = 12 or BCN (n = 12 surgery. After 12 weeks, they were injected with apomorphine to determine erectile function. The penile tissues were harvested and assessed for fibrosis using Masson trichrome staining and for molecular markers of phenotypic modulation using immunohistochemistry and western blotting. CCSMC morphological structure was evaluated by hematoxylin-eosin (H&E staining and transmission electron microscopy (TEM.Erectile function was significantly lower in BCN rats than in sham rats. BCN increased hypoxia-inducible factor-1α and collagen protein expression in corpora cavernous tissue. H&E staining and TEM showed that CCSMCs in BCN rats underwent hypertrophy and showed rough endoplasmic reticulum formation. The expression of CCSMC phenotypic markers, such as smooth muscle α-actin, smooth muscle myosin heavy chain, and desmin, was markedly lower, whereas vimentin protein expression was significantly higher in BCN rats than in control rats.CCSMCs undergo phenotype modulation in rats with cavernous neurectomy. The results have unveiled physiological transformations that occur at the cellular and molecular levels and have helped characterize CN injury-induced ED.

  16. Cavernous angioma in the cisterna magna; Angioma cavernoso na cisterna magna

    Energy Technology Data Exchange (ETDEWEB)

    Settani, Flavio A.P. [Sao Paulo Univ., SP (Brazil); Fontoura, Emilio A.F.; Hweringer, Lindolfo Carlos; Cardoso, Arquimedes Cavalcanti [Hospital do Servidor Publico Estadual, Sao Paulo, SP (Brazil)

    2000-08-01

    We report a rare case of cavernous angioma in the cisterna magna. The diagnosis of this uncommon condition appears to be difficult to establish only upon clinical and radiological findings. In spite of the recent advances in neuroimaging, this type of angiomas is still diagnosed through surgery and histopathological examination. This 21-year-old patient was submitted to a suboccipital craniotomy which disclosed a vascular lesion which was totally removed. (author)

  17. Surgical Management of Cavernous Malformations Presenting with Drug-Resistant Epilepsy

    OpenAIRE

    Alonso-Vanegas, Mario Arturo; Cisneros-Franco, José M.; Otsuki, Taisuke

    2012-01-01

    Cerebral cavernous malformations (CMs) are dynamic lesions characterized by continuous size changes and repeated bleeding. When involving cortical tissue, CMs pose a significant risk for the development of drug-resistant epilepsy, which is thought to be result of an altered neuronal network caused by the lesion itself and its blood degradation products. Preoperative evaluation should comprise a complete seizure history, neurological examination, epilepsy-oriented MRI, EEG, video-EEG, complete...

  18. Insular epilepsy etiology: clinical manifestation and management tactics for cerebral cavernous angiomas

    Directory of Open Access Journals (Sweden)

    R G Khachatryan

    2018-02-01

    Full Text Available Insular epilepsy is currently of special interest for world epileptology. Many authors including W. Penfield and H. Jasper, suggested the relation between unsuccessful temporal resection and undiagnosed epileptic focus localization in insula. Despite increased interest to insular epilepsy, the data on etiologic structure remain sparse. The current paper presents literature review of etiologic role of cavernous angiomas in the origin of insular epilepsy and dissects management tactics on a clinical example. Literature search was performed in Web of Science and «Russian Science Citation Index» databases using keywords «insular epilepsy» (in English and Russian. Using a clinical example, features of manifestation and diagnosis of insular epilepsy are discussed. The international and national data on the morphological structure, localization and features of manifestations of cerebral cavernous angiomas are given. Epilepsy caused by cavernous angiomas constitute 0.4-0.9% in the general structure of the disease, and their ratio increases in the structure of pharmacoresistant forms. Management tactics for the patients with insular epilepsy was analyzed with the use of International League Against Epilepsy guidelines on cavernoma-related epilepsy (2013. Conclusion is made that solitary seizure in epilepsy onset is an indication for magnetic resonance imaging of the brain to exclude structural pathology. High-field magnetic resonance imaging according to epilepsy program is preferable. With no pathological signs on magnetic resonance imaging scans and clinical signs of vascular pathology, magnetic resonance angiography is helpful to exclude vascular malformations. Early microsurgical removal of cavernous angioma as an etiological substrate of epilepsy decreases the risk of pharmacoresistant epilepsy.

  19. Current status of the Demonstration Test of Underground Cavern-Type Disposal Facilities

    International Nuclear Information System (INIS)

    Akiyama, Yoshihiro; Terada, Kenji; Oda, Nobuaki; Yada, Tsutomu; Nakajima, Takahiro

    2011-01-01

    In Japan, the underground cavern-type disposal facilities for low-level waste (LLW) with relatively high radioactivity, mainly generated from power reactor decommissioning, and for certain transuranic (TRU) waste, mainly from spent fuel reprocessing, are designed to be constructed in a cavern 50-100 m underground and to employ an engineered barrier system (EBS) made of bentonite and cement materials. To advance a disposal feasibility study, the Japanese government commissioned the Demonstration Test of Underground Cavern-Type Disposal Facilities in fiscal year (FY) 2005. Construction of a full-scale mock-up test facility in an actual subsurface environment started in FY 2007. The main test objective is to establish the construction methodology and procedures that ensure the required quality of the EBS on-site. A portion of the facility was constructed by 2010, and the test has demonstrated both the practicability of the construction and the achievement of quality standards: low permeability of less than 5x10 -13 m/s and low-diffusion of less than 1x10 -12 m 2 /s at the completion of construction. This paper covers the test results from the construction of certain parts using bentonite and cement materials. (author)

  20. Evaluation of Computational Method of High Reynolds Number Slurry Flow for Caverns Backfilling

    Energy Technology Data Exchange (ETDEWEB)

    Bettin, Giorgia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-05-01

    The abandonment of salt caverns used for brining or product storage poses a significant environmental and economic risk. Risk mitigation can in part be address ed by the process of backfilling which can improve the cavern geomechanical stability and reduce the risk o f fluid loss to the environment. This study evaluate s a currently available computational tool , Barracuda, to simulate such process es as slurry flow at high Reynolds number with high particle loading . Using Barracuda software, a parametric sequence of simu lations evaluated slurry flow at Re ynolds number up to 15000 and loading up to 25%. Li mitations come into the long time required to run these simulation s due in particular to the mesh size requirement at the jet nozzle. This study has found that slurry - jet width and centerline velocities are functions of Re ynold s number and volume fractio n The solid phase was found to spread less than the water - phase with a spreading rate smaller than 1 , dependent on the volume fraction. Particle size distribution does seem to have a large influence on the jet flow development. This study constitutes a first step to understand the behavior of highly loaded slurries and their ultimate application to cavern backfilling.

  1. Rhino-orbitocerebral mucormycosis associated with cavernous sinus thrombosis: case report

    Directory of Open Access Journals (Sweden)

    Haber, Daniel Martiniano

    2008-12-01

    Full Text Available Introduction: Mucormycosis is a rare opportunistic infection caused by Mucorales fungi, and the Rhizopus is the most common one (70% of the cases. It is an acute invasive fungal disease whose form is disseminated, cutaneous, pulmonary, gastrointestinal and rhino-orbitocerebral. The latter is the most common form and its symptoms comprise of unilateral sinusitis, fever and headache. Once established in the orbit the symptoms can be chemosis, diplopia and reduced vision. The infection can spread to the brain via the orbital apex, orbital arteries or via the cribriform plate. Mucormycosis is a medical emergency and the treatment consists of a surgery to an aggressive debridement and in the use of antifungal therapy. Despite the appropriate management, the mortality rate can reach 40% of the cases. One possible intracranial complication of Mucormycosis is the Cavernous Sinus Thrombosis which is a rare and fatal infective disease. The initial symptoms of Cavernous Sinus Thrombosis are headache, retro-orbital pain, periorbital edema, proptosis, diplopia and reduced vision. Case Report: We describe the case of 43-year-old woman with medical history of diabetes mellitus and use of immunosuppressant drugs after kidney transplantation. The patient developed Acute Bacterial Sinusitis and Rhino-orbitocerebral Mucormycosis associated with Cavernous Sinus Thrombosis.

  2. Saline Cavern Adiabatic Compressed Air Energy Storage Using Sand as Heat Storage Material

    Directory of Open Access Journals (Sweden)

    Martin Haemmerle

    2017-03-01

    Full Text Available Adiabatic compressed air energy storage systems offer large energy storage capacities and power outputs beyond 100MWel. Salt production in Austria produces large caverns which are able to hold pressure up to 100 bar, thus providing low cost pressurized air storage reservoirs for adiabatic compressed air energy storage plants. In this paper the results of a feasibility study is presented, which was financed by the Austrian Research Promotion Agency, with the objective to determine the adiabatic compressed air energy storage potential of Austria’s salt caverns. The study contains designs of realisable plants with capacities between 10 and 50 MWel, applying a high temperature energy storage system currently developed at the Institute for Energy Systems and Thermodynamics in Vienna. It could be shown that the overall storage potential of Austria’s salt caverns exceeds a total of 4GWhel in the year 2030 and, assuming an adequate performance of the heat exchanger, that a 10MWel adiabatic compressed air energy storage plant in Upper Austria is currently feasible using state of the art thermal turbomachinery which is able to provide a compressor discharge temperature of 400 °C.

  3. Superselective embolization with Pingyangmycin lipiodol emulsion for the treatment of liver cavernous hemangioma

    International Nuclear Information System (INIS)

    Kong Peng; Lu Huawei; Wang Jiawei; Yan Dong; Li Yingchun; Sun Min; Tan Jing; Tong Yuyun; Teng Yunshan

    2011-01-01

    Objective: To evaluate the advantages and disadvantages of super selective embolization therapy with Pingyangmycin lipiodol emulsion in treating liver cavernous hemangiomas. Methods: One hundred and fifty patients with hepatic cavernous hemangioma underwent super selective hepatic artery embolization treatment with Pingyangmycin lipiodol emulsion. The changes of clinic symptoms and tumor volumes, and the occurrence of complications were observed both before treatment and at 3 and 6 months after treatment. Results: CT scans showed that the blood supply of the tumor disappeared at 3 months and 6 months after treatment, and tumor volume was reduced in all patients. The lipiodol deposited well within the tumor in all patients. The mean tumor diameter was (8.47 ± 2.2 7) cm before intervention, which decreased to (5.75 ± 1.40) cm (P < 0.05) at 6 months after treatment and to (3.51 ± 0.82) cm at 12 months after treatment. The clinic symptoms were alleviated or even disappeared in all patients. No severe complications such as gallbladder injury, bile duct stenosis or hepatic necrosis occurred during and after the therapy. Conclusion: Super selective embolization therapy with Pingyangmycin lipiodol emulsion is an effective, safe and minimally-invasive non-surgical treatment for liver cavernous hemangiomas. With satisfactory clinical results, this technique can be regarded as an ideal embolization therapy. (authors)

  4. Role of fractionated radiotherapy in patients with hemangioma of the cavernous sinus

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sun Min; Yoon, Sang Min; Lee, Su Min; Park, Jin Hong; Song, Si Yeol; Lee, Sang Wook; Ahn, Seung Do; Kim, Jong Hoon; Choi, Eun Kyung [Dept. of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of)

    2017-09-15

    We performed this retrospective study to investigate the outcomes of patients with hemangioma of the cavernous sinus after fractionated radiotherapy. We analyzed 10 patients with hemangioma of the cavernous sinus who were treated with conventional radiotherapy between January 2000 and December 2016. The median patient age was 54 years (range, 31–65 years), and 8 patients (80.0%) were female. The mean hemangioma volume was 34.1 cm{sup 3} (range, 6.8–83.2 cm{sup 3}), and fractionated radiation was administered to a total dose of 50–54 Gy with a daily dose of 2 Gy. The median follow-up period was 6.8 years (range, 2.2–8.8 years). At last follow-up, the volume of the tumor had decreased in all patients. The average tumor volume reduction rate from the initial volume was 72.9% (range, 18.9–95.3%). All 10 of the cranial neuropathies observed before radiation therapy had improved, with complete symptomatic remission in 9 cases (90%) and partial remission in 1 case (10%). No new acute neurologic impairments were reported after radiotherapy. One probable compressive optic neuropathy was observed at 1 year after radiotherapy. Fractionated radiotherapy achieves both symptomatic and radiologic improvements. It is a well-tolerated treatment modality for hemangiomas of the cavernous sinus.

  5. RESISTANCE OF KARST CAVERNS NITROGEN-FIXING BACTERIA TO EXTREME FACTORS

    Directory of Open Access Journals (Sweden)

    Tashyrev O. B.

    2014-10-01

    Full Text Available To determine the studied bacteria resistance quantitative parameters of extreme factors such as toxic metals (Cu2+, organic xenobiotics (p-nitrochlorobenzene and UV-irradiation were the aim of the research. Six strains of nitrogen-fixing bacteria isolated from clays of two caverns Mushkarova Yama (Podolia, Ukraine and Kuybyshevskaya (Western Caucasus, Abkhazia and Azotobacter vinelandii УКМ В-6017 as a reference strain have been tested. For this purpose the maximum permissible concentration of Cu2+ and p-nitrochlorobenzene in the concentration gradient and lethal doses of UV by the survival caverns have been determined. Maximum permissible concentrations for strains were as 10 ppm Cu2+, 70–120 ppm of p-nitrochlorobenzene. The maximum doses of UV-irradiation varied in the range of 55–85 J/m2 (LD99.99. It is shown that three classes of extreme factors resistance parameters of karst caverns strains are similar to the strain of terrestrial soil ecosystems. The most active studied strains reduce the concentration of p-nitrochlorobenzene in the medium in 13 times. The ability of nitrogen-fixing bacteria to degrade p-nitrochlorobenzene could be used in creation new environmental biotechnology for industrial wastewater treatment from nitrochloroaromatic xenobiotics. Isolated strains could be used as destructors for soils bioremediation in agrobiotechnologies and to optimize plants nitrogen nutrition in terrestrial ecosystems.

  6. Diagnosis and treatment of traumatic carotid cavernous fistula combined with sphenoid sinus pseudoaneurysm

    International Nuclear Information System (INIS)

    Chen Huairui; Bai Rulin; Huang Chengguang; Hu Guohan; Luo Chun; Yuan Guoliang; Lu Yicheng

    2008-01-01

    Objective: To explore the diagnosis and treatment of traumatic carotid cavernous fistula combined with sphenoid sinus pseudoaneurysm. Methods: Interventional diagnosed and treated 6 eases of traumatid carotid cavernous fistula combined with sphenoid sinus pseudoaneurysm. Results: 5 patients presented with recurrent massive epistaxis and symptoms of CCF caused by pseudoaneurysms and fistulas were occluded with detachable balloons and internal carotid arteries were reserved in 2 cases; of which, 1 case also had indirect carotid cavernous fistula in contralateral side, embolizated by trans facial vein approach with microcoil. Complete symptoms resolution was achieved in all cases, without procedure related complications. During the follow-up period, all patients returned to their work. Conclusions: Falling from high speed motorcycle without helmet may be one of the main causes of this disease. The site of strike mostly localize at the frontal and lateral aspects of the orbit. MRI scan is very helpful for the diagnosis before receiving angiography. Detachable balloon occlusion for the pseudoaneurysm and fistula is safe and efficient for the treatment. (authors)

  7. Role of EPI in diagnosing cavernous hemangioma and small HCC : comparison with fast T2-weighted MR Imaging

    International Nuclear Information System (INIS)

    Kim, Suk; Lee, Jun Woo; Kim, Chang Won; Jung, Hyun Woo; Choi, Sang Yoel; Lee, Suck Hong; Kim, Byung Soo

    1998-01-01

    The purpose of this study is to compare single-shot echo-planar MR imaging (EPI) with breath-hold fast T2-weighted imaging (HASTE or Turbo spin-echo T2WI) for evaluation of the role of EPI in distinguishing small hepatocellular carcinoma from cavernous hemangioma. We retrospectively evaluated MR images of 35 patients (21 cases of small HCC and 14 cases of cavernous hemangioma). EPI and breath-hold fast T2WI images were obtained and compared on the basis of lesion detection sensitivity, lesion-to-liver signal intensity ratio (SIR), contrast ratio (CR), and lesion-to-liver contrast to noise ratio (CNR). For the detection of small HCC, the sensitivity of EPI and breath-hold fast T2WI were equal in 14 of 21 cases (71.4%). The detection sensitivity of cavernous hemangioma with EPI and breath-hold fast T2WI was 100 % (14/14). Mean SIR on breath-hold fast T2WI was 2.02 ± 0.45 for small HCC and 3.65 ± 0.97 for cavernous hemangioma; on EPI, the corresponding figures were 2.91 ± 0.57 for cavernous hemangioma; On EPI, the figures obtained were 2.27 ± 0.52 and 6.26 ± 2.19, respectively. Mean CNR on breath-hold fast T2WI was 14.24 ± 4.098 for small HCC and 50.28 ± 10.96 for cavernous hemangioma, while on EPI, the corresponding figures were 13.84 ± 3.02 and 45.44 ± 11.21. In detecting focal hepatic mass, the sensitivity of EPI and breath-hold fast T2WI are comparable for the diagnosis of small HCC and cavernous hemangioma, EPI can provided additional information. (author). 20 refs., 2 tabs., 4 figs

  8. Localization techniques in resection of deep seated cavernous angiomas - review and reevaluation of frame based stereotactic approaches.

    Science.gov (United States)

    Slotty, P J; Ewelt, C; Sarikaya-Seiwert, S; Steiger, H-J; Vesper, J; Hänggi, D

    2013-04-01

    Providing high accuracy is crucial in neurosurgery especially for resection of deep seated small cerebral pathologies such as cavernous angiomas. The goal of the present series was to reevaluate the feasibility, accuracy, efficacy and safety of frame-based, stereotactically guided resection for patients suffering from small deep-seated cavernous angiomas. Additionally a review of the literature on navigational tools in cavernoma surgery is provided comparing different navigation strategies. Ten patients with deep-seated, small intracranial, cavernous angiomas being subject to frame-based, stereotactically aided resection are included in this survey. Based on the stereotactic-fused image, set entry and target point aimed at the rim of the cavernoma were calculated. A minicraniotomy (Assets and drawbacks of the stereotactic-aided approach were evaluated, patients were analyzed for surgery-related neurological deficits and completeness of resection. Complete resection was achieved in all ten patients verified by post-surgery MRI imaging. The surgical procedure itself was only slightly aggravated by the stereotactic equipment. No adverse events such as bleedings or infections were observed in our series. Stereotactically guided, minimally invasive resection of deep seated and small cavernous angiomas is accurate and effective. The frame-based stereotactic guidance requires some additional time and effort which seems justified only for deep seated and small cavernous angiomas. Frameless neuronavigation is a common tool in cavernoma surgery and its spatial resolution is sufficient for the majority of cases.

  9. Magnetic Resonance Imaging Comparison of Intra-Articular Cavernous Synovial Hemangioma and Cystic Synovial Hyperplasia of the Knee

    Energy Technology Data Exchange (ETDEWEB)

    De Filippo, M.; Rovani, C.; Sudberry, J. J.; Rossi, F.; Pogliacomi, F.; Zompatori, M. [Univ. of Parma (Italy). Dept. of Clinical Sciences

    2006-07-15

    Purpose: To identify and compare magnetic resonance imaging (MRI) characteristics, with and without intravenous contrast medium, of cavernous synovial hemangiomas and cystic synovial hyperplasia. Material and Methods: Four cases of cavernous synovial hemangioma and five of cystic synovial hyperplasia of the knee were studied retrospectively. The patients (5 F and 4 M; 15-25 years of age) all had long-standing knee pain. At clinical examination we observed elastic swelling and pain without significant joint effusion. The patients underwent conventional radiography and MRI without and following intravenous contrast medium before arthroscopic biopsy. Results: The radiographs were interpreted as negative in all patients. MRI examination without contrast medium revealed a similar multicystic appearance for both lesions. Following intravenous contrast agent administration, cavernous synovial hemangiomas demonstrated avid, rather homogenous enhancement, whereas cystic synovial hyperplasia demonstrated less intense, peripheral enhancement only. Arthroscopy with histological examination of the lesions confirmed the MRI diagnosis in every case. Conclusion: In our experience, cavernous synovial hemangioma and cystic synovial hyperplasia have a similar appearance on unenhanced MRI, but can be reliably differentiated on the basis of enhancement characteristics following intravenous contrast administration. Keywords: Cavernous synovial hemangioma; cystic synovial hyperplasia; knee; MRI.

  10. Acute respiratory failure after aspiration of activated charcoal with recurrent deposition and release from an intrapulmonary cavern.

    Science.gov (United States)

    Francis, Roland C E; Schefold, Joerg C; Bercker, Sven; Temmesfeld-Wollbrück, Bettina; Weichert, Wilko; Spies, Claudia D; Weber-Carstens, Steffen

    2009-02-01

    To report on the recurrent release of charcoal from an intrapulmonary cavern in a case of acute respiratory failure after charcoal aspiration. Case report. Anaesthesiological ICU, university hospital. An 18-year-old ethanol intoxicated comatose patient regurgitated and aspirated activated charcoal during orotracheal intubation. After 2 days of mechanical ventilation, the patient was transferred to a tertiary care university hospital. On admission, acute respiratory distress syndrome with bilateral pulmonary infiltrations was diagnosed. The patient's recovery was hampered by recurrent release of charcoal from an intrapulmonary cavern. Sophisticated ventilatory support, prone positioning, secretolytics, repetitive bronchoscopy, and antibiotic therapy may have facilitated bronchoalveolar clearance and weaning after 18 days. Aspiration may be a dramatic complication if charcoal is administered in comatose patients without airway protection. In this case report, advanced intensive care measures were necessary to tackle the special feature of charcoal release from an intrapulmonary cavern.

  11. Effect of sildenafil in cavernous arteries of patients with erectile dysfunction

    Directory of Open Access Journals (Sweden)

    Claro Joaquim A

    2003-01-01

    Full Text Available INTRODUCTION: Sildenafil citrate is a type 5 phosphodiesterase inhibitor, which has demonstrated excellent results in the treatment of erectile dysfunction. The effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction has not been established yet. The objective of this study was to assess the effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction, following an intracavernous injection of alprostadil. MATERIALS AND METHODS: 29 male patients, with mean age of 53.8 years (32 to 75 years, were prospectively evaluated. The mean time with complaint of erectile dysfunction was 50.5 months (6 to 168 months. Each patient was his own control. Patients underwent a measurement of peak systolic velocity before and after use of sildenafil citrate associated with 5 micrograms of alprostadil, through ultrasonic velocitometry Knoll/MIDUS® system. In the interval between measurements, approximately 15 days, patients used 3 tablets of sildenafil at home with their partners. RESULTS: Using only 5 mcg of alprostadil, average peak systolic velocity was 23.9 cm/s, and when associated to 50 mg of sildenafil it was 24.8 cm/s. Despite the increase in the flow rate caused by sildenafil, the difference was not statistically significant, Zcalculated = - 0.695 NS (Wilcoxon test. Twenty one of the 29 patients (72.4% showed global improvement in sexual performance with the use of sildenafil citrate at home. There was not a statistically significant correlation between the global response to sildenafil citrate and the increase in the peak systolic velocity. CONCLUSION: We concluded that, even though the use of 50 mg of sildenafil citrate associated with 5 mcg of alprostadil provides an increase in the peak systolic velocity of the cavernous arteries, there was no statistic difference in relation to alprostadil alone. There was no correlation between the global response to sildenafil and the increase in

  12. Transarterial embolization of dural carotid cavernous fistulas with low concentration of n-butyl-cyanoacrylate

    International Nuclear Information System (INIS)

    Tan Huaqiao; Li Minghua; Fang Chun; Wang Wu; Cheng Yingsheng; Du Zhuoying; Wang Jue

    2008-01-01

    Objective: To investigate the technique of transarterial embolization of dural carotid- cavernous fistulas (DCCFs) with low concentration (14%-25%) of n-butyl-cyanoacrylate (NBCA) and determine its value. Methods: Eight patients with DCCFs were treated by transarterial embolization with low concentration of NBCA using a wedged microcatheter. Of the 8 patients, 5 had unsuccessful transvenous embolization and 3 could not be treated with transvenous embolization. Results: Transarterial embolization with low concentration of NBCA using a wedged microcatheter resulted in complete obliteration of the affected cavernous sinus and related shunts in 5 patients, no residual arteriovenous shunt was demonstrated on post- embolization angiography. On clinical and angiographic follow-up 6-12 months later, complete resolution of clinical symptoms was observed in all 5 patients and there were no recurrent or residual DCCFs found. Partial obliteration of the involved cavernous sinus and the related shunt was achieved in the remaining 3 patients on immediate post-procedure angiography, but the volume of shunt diminished significantly. On clinical and angiographic follow-up 3 months later, in 2 patients, clinical symptoms were improved and the arteriovenous shunts were diminished; in the third patient, clinical symptom resolved and the shunt was obliterated. There were no major complications except for the transient worsening of ocular symptoms due to VI cranial nerve palsy in 1 patient. Conclusions: Transarterial embolization of DCCFs with low concentration of NBCA using a wedged microcatheter was a safe and effective treatment method. It is an optimal alternative for the patients with DCCFs in which transvenous route was unsuccessful, or impossible. (authors)

  13. Pancreatic portal cavernoma in patients with cavernous transformation of the portal vein: MR findings

    Energy Technology Data Exchange (ETDEWEB)

    Vilgrain, Valerie [Universite Paris 7 Denis Diderot, Paris (France); AP-HP, Hopital Beaujon, Department of Radiology, Clichy (France); INSERM, Centre de recherche Biomedicale Bichat-beaujon, CRB3, Paris (France); Hopital Beaujon, Department of Radiology, Paris (France); Condat, Bertrand; Plessier, Aurelie [AP-HP, Hopital Beaujon, Department of Gastroenterology, Clichy (France); O' Toole, Dermot [Centre de reference des maladies vasculaires du foie, AP-HP, Hopital Beaujon, Department of Hepatology, PMAD, Clichy (France); Ruszniewski, Philippe [Universite Paris 7 Denis Diderot, Paris (France); INSERM, Centre de recherche Biomedicale Bichat-beaujon, CRB3, Paris (France); Centre de reference des maladies vasculaires du foie, AP-HP, Hopital Beaujon, Department of Hepatology, PMAD, Clichy (France); Valla, Dominique C. [Universite Paris 7 Denis Diderot, Paris (France); INSERM, Centre de recherche Biomedicale Bichat-beaujon, CRB3, Paris (France); AP-HP, Hopital Beaujon, Department of Gastroenterology, Clichy (France)

    2009-11-15

    The purpose of the article was to prospectively evaluate the MR findings of pancreatic portal cavernoma in a consecutive series of patients with cavernous transformation of the portal vein. This study was approved by the review board of our institution, and informed consent was obtained. The clinical and biological data and the MR imaging for 20 patients (11 female, 9 male; median age, 49 years) with cavernous transformation of the portal vein and no evidence of previous pancreatic disease were reviewed. The presence of pancreatic portal cavernoma (defined as intra- and/or peripancreatic portal cavernoma), morphological changes in the pancreas, biliary and ductal pancreatic abnormalities, and extension of the portal venous thrombosis were qualitatively assessed. Fifteen patients (75%) had pancreatic portal cavernoma with collateral formation in the pancreas and/or collaterals around the pancreas seen on dynamic contrast-enhanced MR sequences: three patients had both intra- and peripancreatic portal cavernoma, six had intrapancreatic portal cavernoma alone and six had peripancreatic portal cavernoma only. The presence of intra- or peripancreatic portal cavernoma was significantly associated with extension of the thrombosis to the splenic and superior mesenteric veins (p = 0.05). Morphological changes in the pancreas, heterogeneity on T2-weighted sequences and main ductal pancreatic abnormalities were seen in two, four and two patients, respectively. All these patients had intrapancreatic portal cavernoma. Bile duct dilatation was observed in 13 (65%) patients: among them three had extrahepatic dilatation only and these three patients had associated intrapancreatic portal cavernoma. In patients with cavernous transformation of the portal vein, intra- or peripancreatic portal cavernoma is common. In conclusion, intra- or peripancreatic portal cavernoma was only observed in patients with extension of the thrombosis to the splenic vein and/or the superior mesenteric

  14. Pancreatic portal cavernoma in patients with cavernous transformation of the portal vein: MR findings

    International Nuclear Information System (INIS)

    Vilgrain, Valerie; Condat, Bertrand; Plessier, Aurelie; O'Toole, Dermot; Ruszniewski, Philippe; Valla, Dominique C.

    2009-01-01

    The purpose of the article was to prospectively evaluate the MR findings of pancreatic portal cavernoma in a consecutive series of patients with cavernous transformation of the portal vein. This study was approved by the review board of our institution, and informed consent was obtained. The clinical and biological data and the MR imaging for 20 patients (11 female, 9 male; median age, 49 years) with cavernous transformation of the portal vein and no evidence of previous pancreatic disease were reviewed. The presence of pancreatic portal cavernoma (defined as intra- and/or peripancreatic portal cavernoma), morphological changes in the pancreas, biliary and ductal pancreatic abnormalities, and extension of the portal venous thrombosis were qualitatively assessed. Fifteen patients (75%) had pancreatic portal cavernoma with collateral formation in the pancreas and/or collaterals around the pancreas seen on dynamic contrast-enhanced MR sequences: three patients had both intra- and peripancreatic portal cavernoma, six had intrapancreatic portal cavernoma alone and six had peripancreatic portal cavernoma only. The presence of intra- or peripancreatic portal cavernoma was significantly associated with extension of the thrombosis to the splenic and superior mesenteric veins (p = 0.05). Morphological changes in the pancreas, heterogeneity on T2-weighted sequences and main ductal pancreatic abnormalities were seen in two, four and two patients, respectively. All these patients had intrapancreatic portal cavernoma. Bile duct dilatation was observed in 13 (65%) patients: among them three had extrahepatic dilatation only and these three patients had associated intrapancreatic portal cavernoma. In patients with cavernous transformation of the portal vein, intra- or peripancreatic portal cavernoma is common. In conclusion, intra- or peripancreatic portal cavernoma was only observed in patients with extension of the thrombosis to the splenic vein and/or the superior mesenteric

  15. Symptomatic cavernous malformations of the brainstem: functional outcome after microsurgical resection.

    Science.gov (United States)

    Schwartz, Christoph; Grillhösl, Andreas; Schichor, Christian; Suchorska, Bogdana; Romagna, Alexander; Tonn, Jörg-Christian; Zausinger, Stefan

    2013-11-01

    Brainstem cavernous malformations are associated with a considerable risk of hemorrhage and subsequent morbidity. This study provides a detailed work-up of clinical and radiological outcome as well as identification of prognostic factors in patients who had suffered from symptomatic hemorrhages. Patients who had undergone surgery of symptomatic BSCMs were evaluated pre- and postoperatively both neurologically and neuroradiologically supplemented by telephone interviews. Additionally, patients were scored according to the Scandinavian Stroke Scale. Multiple uni- and multivariate analyses of possible clinical and radiological prognostic factors were conducted. The study population comprised 35 patients. Mean age at operation was 39.3 ± 13.0 years with microsurgical resection of a total of 37 different BSCMs between 2002 and 2011. Median clinical follow-up was 44.0 months (range 8-116 months). Postoperative MRI showed eventually complete resection of all BSCMs. Postoperative overall outcome revealed complete resolution of neurological symptoms for 5/35 patients, 14/35 improved and 9/35 remained unchanged. 7/35 suffered from a postoperative new and permanent neurological deficit, mostly affecting the facial nerve or hemipareses with mild impairment. Pre- and postoperative Scandinavian Stroke Scale scores were 11.0 ± 2.4 and 11.4 ± 2.2 (p = 0.55). None of the analyzed factors were found to significantly correlate with patients' clinical outcome. Complete resection of brainstem cavernous malformations can be achieved with an acceptable risk for long-term morbidity and surgery-related new deficits (~20 %). Neurological outcome is mainly determined within the first 6 months after surgery. Surgical treatment of brainstem cavernous malformations is recommended in symptomatic patients, in whom the lesion is accessible for surgery.

  16. The first Inner Detector End-Cap is lowered into the cavern

    CERN Multimedia

    Heinz Pernegger

    The first Inner Detector End-Cap, containing both the SCT and TRT detectors, arriving down the access shaft on the A-side. . The Inner Detector End-Cap A approaching the installation platform. During the difficult phase of inserting the Inner Detector into the cryostat. On Thursday, May 24, the first Inner Detector end-cap, with both the TRT and SCT end-caps, was taken down to the pit. More pictures can be found on the transfer from SR1 to SX1 as well as the lowering into the cavern and reception on the platform which can also be seen as a slide show

  17. Burkitt's lymphoma with bilateral cavernous sinus and mediastinal involvement in a child

    Energy Technology Data Exchange (ETDEWEB)

    Huisman, Thierry A.G.M.; Tschirch, Frank; Schneider, Jacques F.L.; Martin-Fiori, Ernst; Willi, Ulrich V. [Department of Radiology and Magnetic Resonance Imaging, University Children' s Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich (Switzerland); Niggli, Felix [Department of Paediatrics, University Children' s Hospital Zurich, Zurich (Switzerland)

    2003-10-01

    We report a 12-year-old boy who presented with incomplete right ophthalmoplegia, exophthalmos and headache. Initial CT and MRI revealed a mass in the right cavernous sinus. During tumour work-up, CT identified additional tumour within the mediastinum. Biopsy of the mediastinal lesion identified Burkitt's lymphoma. We report on this case because radiologists and clinicians should be alerted to identify sites of primary Burkitt's lymphoma outside of the central nervous system if clinical symptoms indicate, or imaging shows, CNS lesions. Primary CNS involvement in Burkitt's lymphoma is rare. (orig.)

  18. Burkitt's lymphoma with bilateral cavernous sinus and mediastinal involvement in a child

    International Nuclear Information System (INIS)

    Huisman, Thierry A.G.M.; Tschirch, Frank; Schneider, Jacques F.L.; Martin-Fiori, Ernst; Willi, Ulrich V.; Niggli, Felix

    2003-01-01

    We report a 12-year-old boy who presented with incomplete right ophthalmoplegia, exophthalmos and headache. Initial CT and MRI revealed a mass in the right cavernous sinus. During tumour work-up, CT identified additional tumour within the mediastinum. Biopsy of the mediastinal lesion identified Burkitt's lymphoma. We report on this case because radiologists and clinicians should be alerted to identify sites of primary Burkitt's lymphoma outside of the central nervous system if clinical symptoms indicate, or imaging shows, CNS lesions. Primary CNS involvement in Burkitt's lymphoma is rare. (orig.)

  19. First large genomic inversion in familial cerebral cavernous malformation identified by whole genome sequencing.

    Science.gov (United States)

    Spiegler, Stefanie; Rath, Matthias; Hoffjan, Sabine; Dammann, Philipp; Sure, Ulrich; Pagenstecher, Axel; Strom, Tim; Felbor, Ute

    2018-01-01

    Familial cerebral cavernous malformations (CCMs) predispose to seizures and hemorrhagic stroke. Molecular genetic analyses of CCM1, CCM2, and CCM3 result in a mutation detection rate of up to 98%. However, only whole genome sequencing (WGS) in combination with the Manta algorithm for analyses of structural variants revealed a heterozygous 24 kB inversion including exon 1 of CCM2 in a 12-year-old boy with familial CCMs. Its breakpoints were fine-mapped, and quantitative analysis on RNA confirmed reduced CCM2 expression. Our data expand the spectrum of CCM mutations and indicate that the existence of a fourth CCM disease gene is rather unlikely.

  20. Multiple cerebral cavernous malformations in a pediatric patient with Turner syndrome

    Directory of Open Access Journals (Sweden)

    Nicholas T. Gamboa, B.S.

    2017-12-01

    Full Text Available Turner syndrome (TS; 45,X0 is a relatively common chromosomal disorder that is associated with characteristic phenotypic stigmata: short stature, webbed neck, broad (“shield” chest with widely spaced nipples, cubitus valgus, ovarian dysgenesis (“streak ovary”, primary amenorrhea, renal anomalies, lymphedema of the hands or feet, and various vascular abnormalities. Abnormalities of the cardiovascular system are commonly reported in patient with TS, and vascular anomalies affecting various other organ systems are also frequently reported. To date, however, few reports of intracranial vascular malformations exist. The authors report the case of a patient with TS who was found to have multiple cerebral cavernous malformations on imaging.

  1. The benign course of carotid-cavernous fistula in a child

    Energy Technology Data Exchange (ETDEWEB)

    Kurul, Semra E-mail: skurul@hotmail.com; Cakmakci, Handan; Kovanlikaya, Arzu; Dirik, Eray

    2001-08-01

    Carotid-cavernous fistulas (CCF) are reported very rarely in childhood and their clinical course and prognosis are uncertain. We report a 9-year-old boy presented with left eye swelling, neck pain and headache. The MRI findings suggested a CCF with enlarged left superior ophthalmic vein. Ocular Doppler ultrasonography revealed enlarged left superior ophthalmic vein, and arterialization of Doppler wave form. The cerebral angiogram showed normal anatomy. Control Doppler examination findings supported the diagnosis of closure of fistula. The clinical and radiological findings of this unusual presentation are discussed.

  2. The benign course of carotid-cavernous fistula in a child

    International Nuclear Information System (INIS)

    Kurul, Semra; Cakmakci, Handan; Kovanlikaya, Arzu; Dirik, Eray

    2001-01-01

    Carotid-cavernous fistulas (CCF) are reported very rarely in childhood and their clinical course and prognosis are uncertain. We report a 9-year-old boy presented with left eye swelling, neck pain and headache. The MRI findings suggested a CCF with enlarged left superior ophthalmic vein. Ocular Doppler ultrasonography revealed enlarged left superior ophthalmic vein, and arterialization of Doppler wave form. The cerebral angiogram showed normal anatomy. Control Doppler examination findings supported the diagnosis of closure of fistula. The clinical and radiological findings of this unusual presentation are discussed

  3. Suprasellar and third ventricular cavernous malformation: Lessons learned in differential diagnosis and surgical planning.

    Science.gov (United States)

    Kulason, Kay O; Schneider, Julia R; Rahme, Ralph; Ratzon, Fanni; Anderson, Todd A; Shatzkes, Deborah R; Filippi, Christopher G; Costantino, Peter D; Langer, David J; Boockvar, John A

    2017-01-01

    While craniopharyngiomas (CPs) are the most common cystic suprasellar lesions in adults, cavernous malformations (CMs) only exceptionally occur in this location and are seldom considered in the differential diagnosis of such lesions. However, unlike CPs, suprasellar CMs are not typically approached via an endoscopic endonasal approach. We present a unique clinical case of suprasellar and third ventricular CM mimicking a CP, posing a major decision-making dilemma at the levels of both preoperative diagnosis and surgical planning. This case highlights the importance of carefully considering all the differential diagnoses of sellar pathology to select the most appropriate management strategy and surgical approach.

  4. Congenital pial arteriovenous fistula in the temporal region draining into cavernous sinus: A case report

    International Nuclear Information System (INIS)

    Zhang, Ziyin; Wang, Chaohua; Zhang, Changwei; Xie, Xiaodong; Wang, Kun; Tang, Jianjian

    2013-01-01

    This report concerns a 4-month-old infant with progressive prominent and redness of his left eye since birth. This report concerns a 4-month-old infant with progressive prominent redness of his left eye since birth. Angiography revealed a congenital pial arteriovenous fistula between the temporal branch of the left posterior cerebral artery and left cavernous sinus through the sphenoparietal sinus, a condition not reported in the literature. The fistula was successfully occluded with two micro-coils by vertebrobasilar approach.

  5. Interactive evolution concept for analyzing a rock salt cavern under cyclic thermo-mechanical loading

    Science.gov (United States)

    König, Diethard; Mahmoudi, Elham; Khaledi, Kavan; von Blumenthal, Achim; Schanz, Tom

    2016-04-01

    The excess electricity produced by renewable energy sources available during off-peak periods of consumption can be used e.g. to produce and compress hydrogen or to compress air. Afterwards the pressurized gas is stored in the rock salt cavities. During this process, thermo-mechanical cyclic loading is applied to the rock salt surrounding the cavern. Compared to the operation of conventional storage caverns in rock salt the frequencies of filling and discharging cycles and therefore the thermo-mechanical loading cycles are much higher, e.g. daily or weekly compared to seasonally or yearly. The stress strain behavior of rock salt as well as the deformation behavior and the stability of caverns in rock salt under such loading conditions are unknown. To overcome this, existing experimental studies have to be supplemented by exploring the behavior of rock salt under combined thermo-mechanical cyclic loading. Existing constitutive relations have to be extended to cover degradation of rock salt under thermo-mechanical cyclic loading. At least the complex system of a cavern in rock salt under these loading conditions has to be analyzed by numerical modeling taking into account the uncertainties due to limited access in large depth to investigate material composition and properties. An interactive evolution concept is presented to link the different components of such a study - experimental modeling, constitutive modeling and numerical modeling. A triaxial experimental setup is designed to characterize the cyclic thermo-mechanical behavior of rock salt. The imposed boundary conditions in the experimental setup are assumed to be similar to the stress state obtained from a full-scale numerical simulation. The computational model relies primarily on the governing constitutive model for predicting the behavior of rock salt cavity. Hence, a sophisticated elasto-viscoplastic creep constitutive model is developed to take into account the dilatancy and damage progress, as well as

  6. Discussion on environment control technology of escaping cavern to uranium mines

    International Nuclear Information System (INIS)

    Cao Yongkai

    2012-01-01

    As the important refuge of Uranium Mines, the environment of Escaping Cavern is important to the miner's life. In order to attain the standard of Environment Control, the paper gave the method of Environment Control to the fire danger, pervious, collapse; Gave the isolating prevention time; represented the scheme of compressed-air self-help system, high pressure oxygen system, emergency oxygen system; Introduced the air purge equipment to handle the CO, CO 2 , bacterium and other harmful gas. At the same time, gave the method to control the temperature with the phase-change materials and private prevention. (author)

  7. Mechanical stability of a salt cavern submitted to rapid pressure variations: Application to the underground storage of natural gas, compressed air and hydrogen

    International Nuclear Information System (INIS)

    Djizanne-Djakeun, Hippolyte

    2014-01-01

    Salt caverns used for the underground storage of large volumes of natural gas are in high demand given the ever-increasing energy needs. The storage of renewable energy is also envisaged in these salt caverns for example, storage of compressed air and hydrogen mass storage. In both cases, salt caverns are more solicited than before because they are subject to rapid injection and withdrawal rates. These new operating modes raise new mechanical problems, illustrated in particular by sloughing, and falling of overhanging blocks at cavern wall. Indeed, to the purely mechanical stress related to changes in gas pressure variations, repeated dozens of degrees Celsius of temperature variation are superimposed; causes in particular during withdrawal, additional tensile stresses whom may lead to fractures at cavern wall; whose evolution could be dangerous. The mechanical behavior of rock salt is known: it is elasto-viscoplastic, nonlinear and highly thermo sensitive. The existing rock salt constitutive laws and failures and damages criteria have been used to analyze the behavior of caverns under the effects of these new loading. The study deals with the thermo mechanics of rocks and helps to analyze the effects of these new operations modes on the structural stability of salt caverns. The approach was to firstly design and validate a thermodynamic model of the behavior of gas in the cavern. This model was used to analyze blowout in gas salt cavern. Then, with the thermo mechanical coupling, to analyze the effects of rapid withdrawal, rapid injection and daily cycles on the structural stability of caverns. At the experimental level, we sought the optimal conditions to the occurrence and the development of cracks on a pastille and a block of rock salt. The creep behavior of rock salt specimens in triaxial extension also was analyzed. (author)

  8. The first section of the CMS detector (centre of photo) arriving from the vertical shaft, viewed from the cavern floor.

    CERN Document Server

    Maximilien Brice

    2006-01-01

    In the early morning of 2 November, the first section of the CMS detector began its eagerly awaited descent into the underground cavern. You may imagine the CMS detector as a loaf of sliced bread, cut into 15 slices of different sizes. The two HF sections are the end pieces; the slices in between will be lowered sequentially according to their positions in the ‘loaf', starting from the HF+ section at the far end of the cavern, towards the access shaft at the opposite end.

  9. Pyogenic abscess complicating a resolving cerebral haematoma secondary to a cavernous haemangioma: computed tomography and magnetic resonance imaging findings

    International Nuclear Information System (INIS)

    Borsaru, A.D.; Naidoo, P.

    2005-01-01

    A case is discussed of a brain abscess complicating an intracerebral haemorrhage occurring in a cavernous haemangioma. A young child presented with focal seizures as a result of a large intracerebral haemorrhage, occurring in a cavernous haemangioma. The only clue to the underlying vascular malformation was the presence of an associated developmental venous anomaly. The case was complicated by the development of a brain abscess at the site of the intracranial haematoma. The CT and MRI findings are discussed Copyright (2005) Blackwell Publishing Asia Pty Ltd

  10. Giant cavernous carotid aneurysm with spontaneous ipsilateral ICA occlusion: Report of 2 cases and review of literature

    Directory of Open Access Journals (Sweden)

    Savitr BV Sastri

    2013-01-01

    Full Text Available Giant aneurysms of the cavernous carotid artery are rare entities which present predominantly with features of compression of the adjacent neural structures, most commonly the III, IV, VI and V cranial nerves. Historically, treatment options included occlusion of the feeding vessel, direct surgery on the aneurysm, bypass procedures and in recent times, the use of endovascular devices. While intramural thrombus formation is commonly seen in giant aneurysms, we present 2 cases of giant cavernous aneurysms which on evaluation were found to have spontaneous occlusion of the feeding internal carotid artery secondary to thrombus formation, and review the available literature regarding the same.

  11. Surrounding rock mass stability monitoring of underground caverns in a geomechanical model test using FBG sensors

    Science.gov (United States)

    Li, Yong; Zhu, Weishen; Zheng, Wenhua; He, Jianping

    2009-07-01

    Fiber Bragg Gratings (FBG) sensor is widely accepted as a structural stability device for all kinds of geomaterials by either embedding into or bonding onto the structures. The physical model in geotechnical engineering, which can accurately simulate the construction processes and the effects on the stability of underground caverns on basis of satisfying the similarity principles, is an actual physical entity. Due to a large number of restrained factors, a series of experiments are difficult to be carried out, in particular for how to obtain physical parameters during the experiments. Using the geo-mechanical model test of underground caverns in Shuangjiangkou Hydropower Station as a research object, the FBG sensors were mainly focused on and adopted to figure out the problem how to achieve the small displacements in the large-scale model test. The final experimental results show that the FBG sensor has higher measuring accuracy than other conventional sensors like strain gages and mini-extensometers. The experimental results agree well with the numerical simulation results. In the process of building the model, it's successful to embed the FBG sensors in the physical model through making a reserved pore and adding some special glue. In conclusion, FBG sensors can effectively measure the small displacement of monitoring points in the whole process of the geomechanical model test. The experimental results reveal the deformation and failure characteristics of the surrounding rock mass and make some guidance for the in-situ engineering construction.

  12. Odontogenic orbital cellulitis associated with cavernous sinus thrombosis and pulmonary embolism: a case report.

    Science.gov (United States)

    Allegrini, D; Reposi, S; Nocerino, E; Pece, A

    2017-06-20

    This case illustrates the importance of prompt assessment and treatment of orbital cellulitis. In fact the ocular signs and symptoms may be associated with systemic complications which should be investigated and identified as soon as possible to avoid a poor prognosis. A 46-year-old white woman presented to our emergency room with proptosis, ophthalmoplegia, and conjunctival chemosis of her left eye. An ophthalmologist, having diagnosed orbital cellulitis in her left eye, suspected a cavernous sinus thrombosis. Hematochemical and radiological examinations confirmed the cavernous sinus thrombosis and also showed septic pulmonary embolism. A blood culture indicated Streptococcus constellatus, which is a member of the Peptostreptococcus family, a saprophyte of the oral mucosa that can be pathogenic in immunocompromised persons. The odontogenic origin was then confirmed by dental radiography which showed a maxillary abscess. Her eye signs regressed after antibiotic and anticoagulant therapy. This complex case shows the importance of a multidisciplinary approach for the management of orbital cellulitis, for the prompt diagnosis and treatment of eye injuries and possible complications, so as to avoid serious and permanent sequelae.

  13. Effect of radiation therapy on extracerebral cavernous hemangioma in the middle fossa

    International Nuclear Information System (INIS)

    Shibata, Shobu; Fukushima, Masaaki; Mori, Kazuo; Tsujimura, Masaki; Yokoyama, Hiroaki.

    1987-01-01

    We report three cases of extracerebral cavernous hemangiomas in the middle fossa all of which had received radiotherapy. Follow-up study with serial computed tomography during and after irradiation were presented. In Case 1, radiotherapy after partial removal of the tumor reduced the tumor's size and CT number, and facilitated total removal. In Case 2 as well, irradiation was started before the operation. The tumor responded very well to irradiation and showed significant reduction in the size and CT number of the tumor with a dose of about 3,000 rads. Subtotal romoval was possible. In Case 3, the tumor responded very well clinically to irradiation, and vertigo were much improved with a dose of about 3,000 rads, and CT scan at that time showed significant reduction in the size and CT number of the tumor, therefore she only received radiation therapy, no surgical intervention. It is concluded that in cases of extracerebral cavernous hemangioma with massive hemorrhage, radiation of up to 3,000 rads was a method of choice. The treatment results in an increased probability of total removal of the tumor, and moreover the possibility of eliminating surgery. (author)

  14. Study on Mechanical Characteristics of Fully Grouted Rock Bolts for Underground Caverns under Seismic Loads

    Directory of Open Access Journals (Sweden)

    Guoqing Liu

    2017-01-01

    Full Text Available This study establishes an analytical model for the interaction between the bolt and surrounding rock based on the bearing mechanism of fully grouted rock bolts. The corresponding controlled differential equation for load transfer is deduced. The stress distributions of the anchorage body are obtained by solving the equations. A dynamic algorithm for the bolt considering shear damage on the anchoring interface is proposed based on the dynamic finite element method. The rationality of the algorithm is verified by a pull-out test and excavation simulation of a rounded tunnel. Then, a case study on the mechanical characteristics of the bolts in underground caverns under seismic loads is conducted. The results indicate that the seismic load may lead to stress originating from the bolts and damage on the anchoring interface. The key positions of the antiseismic support can be determined using the numerical simulation. The calculated results can serve as a reference for the antiseismic optimal design of bolts in underground caverns.

  15. TIPS Placement via Combined Transjugular and Transhepatic Approach for Cavernous Portal Vein Occlusion: Targeted Approach

    Directory of Open Access Journals (Sweden)

    Natanel Jourabchi

    2013-01-01

    Full Text Available Purpose. We report a novel technique which aided recanalization of an occluded portal vein for transjugular intrahepatic portosystemic shunt (TIPS creation in a patient with symptomatic portal vein thrombosis with cavernous transformation. Some have previously considered cavernous transformation a contraindication to TIPS. Case Presentation. 62-year-old man with chronic pancreatitis, portal vein thrombosis, portal hypertension and recurrent variceal bleeding presents with melena and hematemesis. The patient was severely anemic, hemodynamically unstable, and required emergent portal decompression. Attempts to recanalize the main portal vein using traditional transjugular access were unsuccessful. After percutaneous transhepatic right portal vein access and navigation of a wire through the occluded main portal vein, an angioplasty balloon was inflated at the desired site of shunt takeoff. The balloon was targeted and punctured from the transjugular approach, and a wire was passed into the portal system. TIPS placement then proceeded routinely. Conclusion. Although occlusion of the portal vein increases difficulty of performing TIPS, it should not be considered an absolute contraindication. We have described a method for recanalizing an occluded portal vein using a combined transhepatic and transjugular approach for TIPS. This approach may be useful to relieve portal hypertension in patients who fail endoscopic and/or surgical therapies.

  16. Apparent glacially induced structural controls on limestone conduit development in Ohio Caverns, United States

    Directory of Open Access Journals (Sweden)

    Adrienne M. Watts

    2016-01-01

    Full Text Available Rock discontinuities such as bedding planes and joints are important controls on the form that caves take. We examined structural controls on the development of Ohio Caverns. The cave formed in Devonian limestone underlying a small bedrock knob (Mt. Tabor within the Interior Lowland province, United States. The area has been overridden by continental glaciation multiple times. The bedrock is pervasively fractured, with many curved and wavy near-vertical fractures showing many different orientations. In the case of Ohio Caverns, it appears that the controlling fractures in map view may not be joints sensu stricto, but rather some combination of tensile and shear (mode-1 and mode-2 fractures, probably forming in the regime transition between tensile and shear fracturing. This is easy to envision in a situation with ice advancing over this topographic high, and would result in the curved fractures that are observed in many places in the cave. It can also explain the numerous fracture directions. However, not all fractures are conduit-significant. The cave initiated on or near a single bedding plane, and the cave passages exhibit strong keyhole or plus-sign cross sections. Passage and fracture orientations are inconsistent with regionally expected directions. It is likely that mechanical, hydraulic, and thermal stresses related to glaciation caused the fracturing in Mt. Tabor. The cave then developed on this template according to local hydrologic conditions. This presents a newly documented structural template sub-type for cave development.

  17. Visits to the ATLAS cavern - A record of 20000 visitors in 2006!

    CERN Document Server

    Alessandra Ciocio

    The year 2006 closed with the impressive record of just under 20000 visitors to the ATLAS cavern. These visitors come from all walks of life - people within ATLAS, groups from other CERN divisions, retired CERN staff, school groups both from the local area and from far away, companies looking for something different as a special outing, celebrities (Cirque du Soleil, Black Eyed Peas hip-hop group) passing through Geneva who had read Angels and Demons, a stream of VIP visitors and now, more and more, Press visitors. There have been public visits in the ATLAS cavern since the middle of 2003. At that time a lot of the visitors were guided by Bernard Lebegue and Francois Butin. The total number of visits in 2003 was 2220 people. Not bad for just two guides! Over the following three years demand for visits increased to such an extent that the ATLAS Visits Service was created and is now run very successfully under the supervision of Connie Potter in the ATLAS Secretariat in close collaboration with the ever-helpfu...

  18. Cavernous angioma of the cauda equina: case report Angioma cavernoso de cauda equina: relato de caso

    Directory of Open Access Journals (Sweden)

    Asdrubal Falavigna

    2004-06-01

    Full Text Available We present a rare case of cavernous angioma of the cauda equina and review the eleven cases available in the literature. A 44-year-old woman presented with low back pain and sciatica associated with bowel and bladder dysfunction and motor weakness of the lower extremity. The MRI revealed an enhancing, heterogeneous and hyperintense intradural lesion compressing the cauda equina roots at the L4 level. Laminectomy at L3-L4 and total removal of the tumor were performed without additional neurological deficit. Pathology revealed a cavernous angioma. The literature, clinical presentation, technical examinations, and treatment are reviewed.Relatamos um caso de angioma cavernoso de cauda equina em mulher de 44 anos de idade com sintomas de lombociatalgia associada a fraqueza de membros inferiores e disfunção esfincteriana vesical e anal. Exame de ressonância magnética evidenciou lesão expansiva intradural heterogênea e hiperintensa na cauda eqüina. Indicado tratamento cirúrgico com remoção completa através de laminectomia L3 e L4. O exame anatomopatológico foi compatível com angioma cavernoso. Os onze casos encontrados na literatura são revisados correlacionando a apresentação clínica, tratamento proposto e prognóstico.

  19. Buffer Construction Methodology in Demonstration Test For Cavern Type Disposal Facility

    International Nuclear Information System (INIS)

    Yoshihiro, Akiyama; Takahiro, Nakajima; Katsuhide, Matsumura; Kenji, Terada; Takao, Tsuboya; Kazuhiro, Onuma; Tadafumi, Fujiwara

    2009-01-01

    A number of studies concerning a cavern type disposal facility have been carried out for disposal of low level radioactive waste mainly generated by power plant decommissioning in Japan. The disposal facility is composed of an engineered barrier system with concrete pit and bentonite buffer, and planed to be constructed in sub-surface 50 - 100 meters depth. Though the previous studies have mainly used laboratory and mock-up tests, we conducted a demonstration test in a full-size cavern. The main objectives of the test were to study the construction methodology and to confirm the quality of the engineered barrier system. The demonstration test was planned as the construction of full scale mock-up. It was focused on a buffer construction test to evaluate the construction methodology and quality control in this paper. Bentonite material was compacted to 1.6 Mg/m 3 in-site by large vibrating roller in this test. Through the construction of the buffer part, a 1.6 Mg/m 3 of the density was accomplished, and the data of workability and quality is collected. (authors)

  20. Cavernous sinus thrombophlebitis (sans thrombosis) secondary to odontogenic fascial space infection: an uncommon complication with unusual presentation.

    Science.gov (United States)

    Prabhu, Sundararaman; Jain, Sachin Kumar; Dal Singh, Vankudoth

    2015-03-01

    We discuss an unusual presentation of non-thrombotic cavernous sinus involvement in a patient who was treated for odontogenic fascial space infection arising from a maxillary molar. The highlights were ipsilateral abducens sparing, contralateral abducens involvement and lack of significant orbital congestion. The patient recovered with conservative treatment.

  1. Seizure outcome after resection of cavernous malformations is better when surrounding hemosiderin-stained brain also is removed.

    Science.gov (United States)

    Baumann, Christian R; Schuknecht, Bernhard; Lo Russo, Giorgio; Cossu, Massimo; Citterio, Alberto; Andermann, Frederick; Siegel, Adrian M

    2006-03-01

    Considering the epileptogenic effect of cavernoma-surrounding hemosiderin, assumptions are made that resection only of the cavernoma itself may not be sufficient as treatment of symptomatic epilepsy in patients with cavernous malformations. The purpose of this study was to test the hypothesis whether seizure outcome after removal of cavernous malformations may be related to the extent of resection of surrounding hemosiderin-stained brain tissue. In this retrospective study, 31 consecutive patients with pharmacotherapy-refractory epilepsy due to a cavernous malformation were included. In all patients, cavernomas were resected, and all patients underwent pre- and postoperative magnetic resonance imaging (MRI). We grouped patients according to MRI findings (hemosiderin completely removed versus not/partially removed) and compared seizure outcome (as assessed by the Engel Outcome Classification score) between the two groups. Three years after resection of cavernomas, patients in whom hemosiderin-stained brain tissue had been removed completely had a better chance for a favorable long-term seizure outcome compared with those with detectable postoperative hemosiderin (p=0.037). Our study suggests that complete removal of cavernoma-surrounding hemosiderin-stained brain tissue may improve epileptic outcome after resection of cavernous malformations.

  2. Seizure outcome after surgical resection of supratentorial cavernous malformations plus hemosiderin rim in patients with short duration of epilepsy.

    Science.gov (United States)

    Jin, Yichao; Zhao, Changyi; Zhang, Shilei; Zhang, Xiaohua; Qiu, Yongming; Jiang, Jiyao

    2014-04-01

    The objective of this study was to retrospectively review the postoperative seizure outcome in patients with short duration of epilepsy associated with cavernous malformations and analyze the effect of surgical methods on seizure outcome in such population. 36 patients with short duration of epilepsy (shorter than 12 months) associated with cavernous malformations in temporal or frontal lobe underwent microsurgical resection. The patients were retrospectively divided into two groups: Group A (21 patients) with complete removal of hemosiderin rim and Group B (15 patients) with partial removal of hemosiderin rim. Clinical follow-up was achieved with telephone correspondence or outpatient assessment. The seizure outcome was based on Engel's classification. After a mean follow-up period of 18 months, 77.8% of the patients (28/36) were classified into Engel class I, including 19 patients (90.5%) in the complete removal of hemosiderin rim group (Group A) and 9 patients (60%) in the partial removal of hemosiderin rim group (Group B). Seizure outcome was significantly better in Group A. There was no mortality and all the postoperative neurological deficits were recovered at the time of follow-up. The analysis of the seizure outcome demonstrate patients with short duration of epilepsy associated with cavernous malformations could benefit greatly from complete resection of hemosiderin rim and cavernous malformations. Copyright © 2014 Elsevier B.V. All rights reserved.

  3. An Investigation of the Integrity of Cemented Casing Seals with Application to Salt Cavern Sealing and Abandonment

    Energy Technology Data Exchange (ETDEWEB)

    Pfeifle, T.W.; Mellegard, K.D.; Skaug, N.T.; Bruno, M.S.

    2001-04-19

    This research project was pursued in three key areas. (1) Salt permeability testing under complex stress states; (2) Hydraulic and mechanical integrity investigations of the well casing shoe through benchscale testing; and (3) Geomechanical modeling of the fluid/salt hydraulic and mechanical interaction of a sealed cavern.

  4. Design and operation problems related to water curtain system for underground water-sealed oil storage caverns

    Directory of Open Access Journals (Sweden)

    Zhongkui Li

    2016-10-01

    Full Text Available The underground water-sealed storage technique is critically important and generally accepted for the national energy strategy in China. Although several small underground water-sealed oil storage caverns have been built in China since the 1970s, there is still a lack of experience for large-volume underground storage in complicated geological conditions. The current design concept of water curtain system and the technical instruction for system operation have limitations in maintaining the stability of surrounding rock mass during the construction of the main storage caverns, as well as the long-term stability. Although several large-scale underground oil storage projects are under construction at present in China, the design concepts and construction methods, especially for the water curtain system, are mainly based on the ideal porosity medium flow theory and the experiences gained from the similar projects overseas. The storage projects currently constructed in China have the specific features such as huge scale, large depth, multiple-level arrangement, high seepage pressure, complicated geological conditions, and high in situ stresses, which are the challenging issues for the stability of the storage caverns. Based on years' experiences obtained from the first large-scale (millions of cubic meters underground water-sealed oil storage project in China, some design and operation problems related to water curtain system during project construction are discussed. The drawbacks and merits of the water curtain system are also presented. As an example, the conventional concept of “filling joints with water” is widely used in many cases, as a basic concept for the design of the water curtain system, but it is immature. In this paper, the advantages and disadvantages of the conventional concept are pointed out, with respect to the long-term stability as well as the safety of construction of storage caverns. Finally, new concepts and principles

  5. Stability and support issues in the construction of large span caverns for physics

    Energy Technology Data Exchange (ETDEWEB)

    Laughton, C.; /Fermilab

    2008-05-01

    New physics experiments, proposed to study neutrinos and protons, call for the use of large underground particle detectors. In the United States, such detectors would be housed in the US Deep Underground Science and Engineering Laboratory (DUSEL), sited within the footprint of the defunct Homestake Mine, South Dakota. Although the experimental proposals differ in detail, all rely heavily upon the ability of the mined and reinforced rock mass to serve as a stable host for the detector facilities. Experimental proposals, based on the use of Water Cherenkov detector technology, specify rock caverns with excavated volumes in excess of half a million cubic meters, spans of at least 50 m, sited at depths of approximately one to 1.5 kilometers. Although perhaps sited at shallower depth, proposals based on the use of Liquid Argon (LAr) detector technology are no less challenging. LAr proposals not only call for the excavation of large span caverns, but have an additional need for the safe management of large quantities (kilo-tonnes) of cryogenic liquid, including critical provisions for the fail-safe egress of underground personnel and the reliable exhaust of Argon gas in the event of a catastrophic release. These multi-year, high value physics experiments will provide the key experimental data needed to support the research of a new generation of physicists as they probe the behavior of basic particles and the fundamental laws of nature. The rock engineer must deliver caverns that will reliably meet operational requirements and remain stable for periods conservatively estimated to be in excess of twenty years. This paper provides an overview of the DUSEL site conditions and discusses key end-user requirements and design criteria likely to dominate in determining the viability of experimental options. The paper stresses the paramount importance of collecting adequate site-specific data to inform early siting, dimensioning and layout decisions. Given the large-scale of the

  6. Hemangioma cavernoso intramedular: relato de caso Spinal cord intramedullary cavernous haemangioma: case report

    Directory of Open Access Journals (Sweden)

    Juliano Colonetti

    2003-09-01

    Full Text Available O hemangioma cavernoso intramedular é anomalia vascular de baixo fluxo, curável através de ressecção cirúrgica. Entretanto, se não forem instituídos o diagnóstico precoce e a terapêutica adequada, pode levar à graves sequelas neurológicas. É extremamente raro a ocorrência de um angioma cavernoso intramedular. É relatado o caso de uma paciente de 33 anos, com um angioma cavernoso intramedular no nível de T6 - T7, que apresentava quadro clínico de compressão medular lenta e progressiva, com piora recente importante. A ressonância magnética da coluna torácica demonstrou, entre a sexta e a sétima vértebras dorsais, lesão expansiva intramedular que se apresentava hipointensa em T1 e discretamente hiperintensa em T2, com pequeno halo hipointenso à sua volta nas duas sequências. A paciente foi submetida a tratamento cirúrgico tardio e não apresentou recuperação neurológica. Os achados clínicos, de imagem e a importância de instituir precocemente o tratamento adequado são analisados e discutidos.The intramedullary cavernous haemangioma is a low flow vascular anomaly curable through surgical resection, howewer if the precocious diagnosis and the appropriate therapeutics are not done it can cause serious neurological sequels.It is extremely rare the occurrence of intramedullary cavernous haemangioma. We report the case of a 33 year-old woman patient with an intramedullary cavernous angioma at T6-T7, that presented a clinical picture of slow and progressive spinal cord compression , with an important recent worsening.The magnetic resonance of the thoracic column demonstrated a T6 - T7 a intramedullary expansive lesion wich presented hypointense on T1 and discretely hyperintense on T2 with a small hypointense area in the two sequences.The patient was submitted to late surgical treatment and did not presented neurological recovery. The clinical and imagelogy pictures, and the importance of instituing precociously the

  7. CNS cavernous haemangioma: “popcorn” in the brain and spinal cord

    International Nuclear Information System (INIS)

    Hegde, A.N.; Mohan, S.; Lim, C.C.T.

    2012-01-01

    Cavernous haemangiomas (CH) are relatively uncommon non-shunting vascular malformations of the central nervous system and can present with seizures or with neurological deficits due to haemorrhage. Radiologists can often suggest the diagnosis of CH based on characteristic magnetic resonance imaging (MRI) features, thus avoiding further invasive procedures such as digital subtraction angiography or surgical biopsy. Although typical MRI appearance combined with the presence of multiple focal low signal lesions on T2*-weighted images or the presence of one or more developmental venous anomaly within the brain can improve the diagnostic confidence, serial imaging studies are often required if a solitary CH presents at a time when the imaging appearances had not yet matured to the typical “popcorn” appearance.

  8. Evaluation on construction quality of pit filler material of cavern type radioactive waste disposal facility

    International Nuclear Information System (INIS)

    Takechi, Shin-ichi; Yokozeki, Kosuke; Shimbo, Hiroshi; Terada, Kenji; Akiyama, Yoshihiro; Yada, Tsutomu; Tsuji, Yukikazu

    2014-01-01

    The pit filler material of the underground cavern-type radioactive waste disposal facility, which is poured directly around the radioactive waste packages where high temperature environment is assumed by their decay heat, is concerned to be adversely affected on the filling behavior and its hardened properties. There also are specific issues that required quality of construction must be achieved by unmanned construction with remote operation, because the pit filler construction shall be done under radiation environment. In this paper, the mix proportion of filler material is deliberated with filling experiments simulating high temperature environment, and also the effect of temperature on hardened properties are confirmed with high temperature curing test. Subsequently, the feasibility of unmanned construction method of filler material by pumping, and by movable bucket, are comparatively discussed through a real size demonstration. (author)

  9. Demonstration test of underground cavern-type disposal facilities, fiscal 2010 status - 59180

    International Nuclear Information System (INIS)

    Akiyama, Yoshihiro; Terada, Kenji; Oda, Nobuaki; Yada, Tsutomu; Nakajima, Takahiro

    2012-01-01

    A test to demonstrate practical construction technology for underground cavern-type disposal facilities is currently underway. Cavern-type disposal facilities are a radioactive waste repository excavated to a depth of 50 to 100 m below ground and constructed with an engineered barrier system (EBS) that is a combination of low-permeable bentonite material and low-diffusive cementitious material. The disposed materials are low-level radioactive waste with relatively high radioactivity, mainly generated from power reactor decommissioning, and certain transuranic wastes that are mainly generated from spent fuel reprocessing. The project started in fiscal 2005*, and since fiscal 2007 a full-scale mock-up of a disposal facility has been constructed in an actual sub-surface environment. The main objective of the demonstration test is to establish construction procedures and methods which ensure the required quality of an EBS on-site. Certain component parts of the facility had been constructed in an underground cavern by fiscal 2010, and tests so far have demonstrated both the practicability of the construction and the achievement of the required quality. This paper covers the project outline and the test results obtained by the construction of certain EBS components. The following results were obtained from the construction test of EBS in the test cavern: 1) The dry density of bentonite buffer at the lower layer constructed by vibratory compaction shows that 95% of core samples have densities within the target range. 2) The specified mix for the low-diffusion layer has uniform density and crack-control properties, and meets the requirements for diffusion performance. 3) The specified mix of the concrete pit has sufficient passing ability through congested reinforcement and meets the requirements of strength performance. 4) The dry density of the bentonite buffer at the lateral layer constructed by the spraying method shows that 65% of the core samples are within the

  10. Unilateral facial palsy in an infant: an unusual presentation of familial multiple cerebral cavernous malformation.

    LENUS (Irish Health Repository)

    Zakaria, Zaitun

    2012-01-01

    Cerebral cavernous malformation (CCM) in infants tends to have genetic predisposition. These cavernomas have a progressive course of events and associated neurological symptoms with increase in age. They most commonly present with seizure and syndrome of increased intracranial pressure comprising of headache, vomiting and focal neurological signs. We describe a case of a 7-month-old infant who presented with an acute onset of right facial paralysis with a background of familial CCM. The CT and MRI scan revealed fresh haemorrhage in the right cerebellar and pontine cavernomas with surrounding oedema and no evidence of obstructive hydrocephalus. These two cavernomas re-bled in a week duration causing episodes of incessant crying and irritability. After discussing the pros and cons of treatment, owing to stable clinical status, the patient is currently been managed conservatively.

  11. Cavernous Malformation Associated With Arterialized Developmental Venous Anomaly: A Case Report.

    Science.gov (United States)

    Nakase, Kenta; Motoyama, Yasushi; Nakai, Tokiko; Takeshima, Yasuhiro; Nakagawa, Ichiro; Park, Young-Su; Ohbayashi, Chiho; Nakase, Hiroyuki

    2017-06-01

    Formation of cavernous malformations (CMs) has been recognized to be associated with developmental venous anomaly (DVA) by many authors. Hemodynamic stress due to venous outflow restriction could be hypothesized as a cause. On the other hand, a rare subgroup of DVA with an arterial component has been reported as likely to hemorrhage or be symptomatic. Cases of arterialized DVAs reported previously have not been associated with the presence of CM. We present herein a case report of arterialized DVA in the brainstem with repeated cerebellar hemorrhage. The 49-year-old patient was treated with surgical evacuation of hematoma. A surgical specimen from the hematoma cavity demonstrated CMs on histological examination. To the best of our knowledge, this represents the first report of CM associated with an arterialized DVA. In addition to venous congestion due to outflow obstruction, bleeding from the arterial component of the DVA might be considered as a cause of CM formation.

  12. Simulations of argon accident scenarios in the ATLAS experimental cavern a safety analysis

    CERN Document Server

    Balda, F

    2002-01-01

    Some characteristic accidents in the ATLAS experimental cavern (UX15) are simulated by means of STAR-CD, a code using the "Finite-Volume" method. These accidents involve different liquid argon leaks from the barrel cryostat of the detector, thus causing the dispersion of the argon into the Muon Chamber region and the evaporation of the liquid. The subsequent temperature gradients and distribution of argon concentrations, as well as their evolution in time are simulated and discussed, with the purpose of analysing the dangers related to asphyxiation and to contact with cryogenic fluids for the working personnel. A summary of the theory that stands behind the code is also given. In order to validate the models, an experimental test on a liquid argon spill performed earlier is simulated, showing that the program is able to output reliable results. At the end, some safety-related recommendations are listed.

  13. Embolization of carotid-cavernous fistula using a silicone balloon and a tracker-catheter system

    International Nuclear Information System (INIS)

    Kim, Sun Yong; Cho, Kil Ho; Park, Bok Hwan

    1992-01-01

    With the recent introduction and development of the detachable balloon system, it has become the treatment of choice in the management of carotid cavernous fistulas(CCFs). But, since most delivery systems for embolization of CCF mainly depend on flow guidance for balloon delivery, in case of small fistula, pseudo aneurysm and arterialized venous collaterals, failure of balloon embolization can occur. To overcome these limitation, the authors designed and used a new versatile, steerable, and flow-guided detachable balloon system by using a Tracker catheter system with silicone or latex balloons. Using this maneuver, we could get successful fistula occlusion in 7 out of 8 patients (silicone balloon). But in one case, we had to occlude the internal carotid artery at the fistula site, proximal and distal cervical portions of the internal carotid artery. This balloon delivery system proved to provide high selectivity for fistula and relatively ease of handing

  14. Carotid-Cavernous Fistula in Ehlers-Danlos Syndrome by Pure Transvenous Approach

    Science.gov (United States)

    Van Overmeire, O.; De Keukeleire, K.; Van Langenhove, P.; Defreyne, L.

    2006-01-01

    Summary We describe a carotid-cavernous fistula (CCF) in a middle aged woman with Ehlers-Danlos syndrome (EDS) type IV, which manifested with a left-sided ophthalmoplegia. The CCF was diagnosed on magnetic resonance imaging. To prevent potential lethal arterial wall injury, the CCF was treated endovascularly under local anesthesia and exclusively by a transvenous approach. The fistula was successfully closed with Guglielmi Detachable Coils. Notwithstanding these precautionary measures, the patient suffered an intraperitoneal and a small retroperitoneal bleed during the procedure and died suddenly ten days after intervention in hemorrhagic shock. A review of recent literature focussing on the technique of transvenous approach and the catheterization risks of CCF in Ehlers-Danlos syndrome is presented. PMID:20569551

  15. Spontaneous Carotid-Cavernous Fistula in the Type IV Ehlers-Danlos Syndrome

    Science.gov (United States)

    Kim, Jeong Gyun; Cho, Won-Sang; Kim, Jeong Eun

    2014-01-01

    Ehlers-Danlos syndrome (EDS) is a rare inherited connective disease. Among several subgroups, type IV EDS is frequently associated with spontaneous catastrophic bleeding from a vascular fragility. We report on a case of carotid-cavernous fistula (CCF) in a patient with type IV EDS. A 46-year-old female presented with an ophthalmoplegia and chemosis in the right eye. Subsequently, seizure and cerebral infarction with micro-bleeds occurred. CCF was completely occluded with transvenous coil embolization without complications. Thereafter, the patient was completely recovered. Transvenous coil embolization can be a good treatment of choice for spontaneous CCF with type IV EDS. However, every caution should be kept during invasive procedure. PMID:24653803

  16. Interventional Treatment of a Symptomatic Neonatal Hepatic Cavernous Hemangioma Using the Amplatzer Vascular Plug

    International Nuclear Information System (INIS)

    Kretschmar, Oliver; Knirsch, Walter; Bernet, Vera

    2008-01-01

    Percutaneous intervention is one treatment option for symptomatic hepatic hemangioma in infants. We report the case of a newborn (birth weight 4060 g) with a large hepatic cavernous hemangioma, which presented early with high cardiac output failure due to arteriovenous shunting and signs of incipient Kasabach-Merritt syndrome. We performed a successful superselective transcatheter coil embolization of three feeding arteries on the seventh day of life. Because of remaining diffuse very small arteries causing a relevant residual shunt, additional occlusion of the three main draining veins was necessary with three Amplatzer vascular plugs. Cardiac failure resolved immediately. Without any additional therapy the large venous cavities disappeared within the following months. The tumor continues to regress in size 8 months after the intervention

  17. Vascular permeability and iron deposition biomarkers in longitudinal follow-up of cerebral cavernous malformations

    DEFF Research Database (Denmark)

    Girard, Romuald; Fam, Maged D; Zeineddine, Hussein A

    2017-01-01

    and quantifiable biomarkers of disease activity in CCMs. This may be applied in natural history studies and may help calibrate clinical trials. The 2 techniques are likely applicable in other disorders of vascular integrity and iron leakage such as aging, hemorrhagic microangiopathy, and traumatic brain injury....... permeability at baseline (p = 0.001), as well as higher regional permeability (p = 0.003) in the area that would later develop a new lesion as compared with the homologous contralateral brain region. CONCLUSIONS In vivo assessment of vascular permeability and iron deposition on MRI can serve as objective......OBJECTIVE Vascular permeability and iron leakage are central features of cerebral cavernous malformation (CCM) pathogenesis. The authors aimed to correlate prospective clinical behavior of CCM lesions with longitudinal changes in biomarkers of dynamic contrast-enhanced quantitative permeability...

  18. Cavernous sinus thrombosis following dental extraction: a rare case report and forgotten entity.

    Science.gov (United States)

    Aggarwal, Karun; Rastogi, Sanjay; Joshi, Atul; Kumar, Ashish; Chaurasia, Archana; Prakash, Rajat

    2017-10-01

    Prior to the advent of efficacious antimicrobial agents, the mortality rate from cavernous sinus thrombosis (CST) was effectively 100%. There have been very few reports of CST associated with tooth extraction. A 40-year-old female presented to the emergency room with swelling over the right side of the face and history of extraction in the upper right region by an unregistered dental practitioner. The patient presented with diplopia, periorbital ecchymosis, and chemosis of the right eye. A computed tomography scan revealed venous dilatation of the right superior ophthalmic vein. The patient was immediately treated with incision and drainage, intravenous antibiotics, and heparin (low molecular weight). Unfortunately, the patient died two days after surgery due to complications from the disease. CST is a rare disease with a high mortality rate. Therefore, dental health education in rural areas, legal action against unregistered dental practitioners, early diagnosis, and aggressive antibiotic treatment can prevent future mortality resulting from CST.

  19. High voltage irradiation of a cavernous giant haemangioma? An impressive case example

    International Nuclear Information System (INIS)

    Proske, H.; Pfab, R.

    1992-01-01

    Because of multifonus of therapeutic possibilities in treating cavernous haemangioma, we mostly, but primarily due to frequent spontaneous regression tendency, we exercise restraint. However, if irradiation is taken into consideration, it is mainly with 'soft' X-rays (100 kV). The application of high voltage X-rays (1 MeV) by means of linear accelerator is seldom and rarely found in literature. That this method can be effective and indication for this is absolutely in order and life-saving, is described in an impressive case example of a congenital giant haemangioma on the right facial half of an infant, where all other previous forms of therapeutical procedures had failed. (orig.) [de

  20. CEREBRAL CAVERNOUS MALFORMATION COEXISTING WITH PITUITARY ADENOMA, HASHIMOTO THYROIDITIS AND MENTAL ILLNESS: FIRST CASE REPORT.

    Directory of Open Access Journals (Sweden)

    Sara Guido

    2017-10-01

    Full Text Available Cerebral Cavernous Malformations (CCMs are vascular lesions involving brain capillaries. They may occur sporadically or be inherited as autosomal dominant character. Due to incomplete penetrance, CCMs incidence is underestimated and, overall sporadic cases, are often accidentally diagnosed. Rarely CCMs are linked to other pathological conditions. Here we present the first case in literature of a young woman affected by sporadic CCM, pituitary adenoma, Hashimoto thyroiditis and mental illness of unknown etiology. Symptoms’ analysis suggests that she may suffer of Hashimoto encephalopathy (HE, a condition that in very few cases develops together with Hashimoto thyroiditis. Genetic bases of HE are still unknown and symptomatology is very heterogeneous. This paper is a preliminary report of the case and is focused on complexity of clinical manifestations that makes the diagnosis uncertain. If our hypothesis will be confirmed by further analysis, our aim will be to clarify genetic causes of HE.

  1. Cavernous sinus thrombosis following dental extraction: a rare case report and forgotten entity

    Science.gov (United States)

    2017-01-01

    Prior to the advent of efficacious antimicrobial agents, the mortality rate from cavernous sinus thrombosis (CST) was effectively 100%. There have been very few reports of CST associated with tooth extraction. A 40-year-old female presented to the emergency room with swelling over the right side of the face and history of extraction in the upper right region by an unregistered dental practitioner. The patient presented with diplopia, periorbital ecchymosis, and chemosis of the right eye. A computed tomography scan revealed venous dilatation of the right superior ophthalmic vein. The patient was immediately treated with incision and drainage, intravenous antibiotics, and heparin (low molecular weight). Unfortunately, the patient died two days after surgery due to complications from the disease. CST is a rare disease with a high mortality rate. Therefore, dental health education in rural areas, legal action against unregistered dental practitioners, early diagnosis, and aggressive antibiotic treatment can prevent future mortality resulting from CST. PMID:29142871

  2. Speleological study of the cavern of the Ecce homo hill, in the municipality of Chimichagua, Cesar

    Directory of Open Access Journals (Sweden)

    Frank David Lascarro-Navarro

    2015-06-01

    Full Text Available In the municipality of Chimichagua, Cesar, there is a system of natural caves associated with carbonate sedimentary rocks, which have suffered chemical dissolution and mechanical erosion generating exokarstic and endokarstic processes, which explain the geochemical and morphological phenomena that have given rise to these cavities. This study presents the results of a speleological work performed to the cavern of the Eccehomo Hill, located in the municipality of Chimichagua department of Cesar, concluding that the lithostratigraphic units outside and inside of the cavities are micritic and micritic limestones with fossils that according to the classification of Folk (1974, belong to the Formation Aguas Blancas, of the Cogollo Group. The cavities possess throughout their extension, variety of speleothems, endokarstic process products such as stalactites, moonmilk, castings, flags, sawtooth, found in the walls and ceiling.

  3. Cavernous sinus thrombosis syndrome and brainstem involvement in patient with leptospirosis: Two rare complications of leptospirosis

    Directory of Open Access Journals (Sweden)

    Shahriyar Alian

    2014-01-01

    Full Text Available Leptospirosis is a bacterial disease that is caused by pathogenic spirochetes of the genus Leptospira. It can affect humans and animals. In humans, it can lead to a wide spectrum of symptoms. It is known as the most common zoonosis in the world. The typical presentation of the disease is an acute biphasic febrile illness with or without jaundice. Less common clinical manifestations may result from involvement of different human body systems. In many places, this disease may be under-diagnosed, especially when associated with neurological complications. Moreover, without treatment, leptospirosis can lead to organ damages, and even death. Neurological complications are uncommon and are reported in a few cases. Cavernous sinus thrombosis syndrome and brainstem involvement are rare complications of leptospirosis and are associated with a high mortality risk. To our knowledge, no such cases have been reported in the literature.

  4. Characterization of bedded salt for storage caverns -- A case study from the Midland Basin, Texas

    Energy Technology Data Exchange (ETDEWEB)

    Hovorka, Susan D.; Nava, Robin

    2000-06-13

    The geometry of Permian bedding salt in the Midland Basin is a product of interaction between depositional facies and postdepositional modification by salt dissolution. Mapping high-frequency cycle patterns in cross section and map view using wireline logs documents the salt geometry. Geologically based interpretation of depositional and dissolution processes provides a powerful tool for mapping and geometry of salt to assess the suitability of sites for development of solution-mined storage caverns. In addition, this process-based description of salt geometry complements existing data about the evolution of one of the best-known sedimentary basins in the world, and can serve as a genetic model to assist in interpreting other salts.

  5. Carotid cavernous fistula with central retinal artery occlusion and Terson syndrome after mid-facial trauma

    Directory of Open Access Journals (Sweden)

    Karna, Satya

    2017-05-01

    Full Text Available Objectives: To report a rare occurrence combination of central retinal artery occlusion (CRAO and Terson syndrome in a Barrow’s type A carotid cavernous fistula (CCF patient.Methods: Observational case report.Results: A twenty-year-old male patient with a history of road traffic accident presented with periorbital swelling and redness in the left eye. Examination revealed a CRAO with intraretinal and preretinal hemorrhages. On imaging, type A CCF and subarachnoid hemorrhage were detected. He underwent embolization of the fistula for cosmetic blemish. The possible mechanisms and clinical implications are discussed. Conclusion: Patients with a head injury can have serious ocular damage. Posterior segment manifestations of CCFs are varied and at times can occur in various rare combinations, making it challenging. Early recognition of these rare manifestations and a multi-disciplinary approach are needed in patients with head trauma.

  6. A servo controlled gradient loading triaxial model test system for deep-buried cavern

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Xu-guang [College of Engineering, Ocean University of China, Qingdao 266100 (China); Shandong Provincial Key Laboratory of Ocean Engineering, Qingdao 266100 (China); Research Center of Geotechnical and Structural Engineering, Shandong University, Jinan 250061 (China); Zhang, Qiang-yong; Li, Shu-cai [Research Center of Geotechnical and Structural Engineering, Shandong University, Jinan 250061 (China)

    2015-10-15

    A servo controlled gradient loading model test system is developed to simulate the gradient geostress in deep-buried cavern. This system consists of the gradient loading apparatus, the digital servo control device, and the measurement system. Among them, the gradient loading apparatus is the main component which is used for exerting load onto the model. This loading apparatus is placed inside the counterforce wall/beam and is divided to several different loading zones, with each loading zone independently controlled. This design enables the gradient loading. Hence, the “real” geostress field surrounding the deep-buried cavern can be simulated. The loading or unloading process can be controlled by the human-computer interaction machines, i.e., the digital servo control system. It realizes the automation and visualization of model loading/unloading. In addition, this digital servo could control and regulate hydraulic loading instantaneously, which stabilizes the geostress onto the model over a long term. During the loading procedure, the collision between two adjacent loading platens is also eliminated by developing a guide frame. This collision phenomenon is induced by the volume shrinkage of the model when compressed in true 3D state. In addition, several accurate measurements, including the optical and grating-based method, are adopted to monitor the small deformation of the model. Hence, the distortion of the model could be accurately measured. In order to validate the performance of this innovative model test system, a 3D geomechanical test was conducted on a simulated deep-buried underground reservoir. The result shows that the radial convergence increases rapidly with the release of the stress in the reservoir. Moreover, the deformation increases with the increase of the gas production rate. This observation is consistence with field observation in petroleum engineering. The system is therefore capable of testing deep-buried engineering structures.

  7. A servo controlled gradient loading triaxial model test system for deep-buried cavern

    International Nuclear Information System (INIS)

    Chen, Xu-guang; Zhang, Qiang-yong; Li, Shu-cai

    2015-01-01

    A servo controlled gradient loading model test system is developed to simulate the gradient geostress in deep-buried cavern. This system consists of the gradient loading apparatus, the digital servo control device, and the measurement system. Among them, the gradient loading apparatus is the main component which is used for exerting load onto the model. This loading apparatus is placed inside the counterforce wall/beam and is divided to several different loading zones, with each loading zone independently controlled. This design enables the gradient loading. Hence, the “real” geostress field surrounding the deep-buried cavern can be simulated. The loading or unloading process can be controlled by the human-computer interaction machines, i.e., the digital servo control system. It realizes the automation and visualization of model loading/unloading. In addition, this digital servo could control and regulate hydraulic loading instantaneously, which stabilizes the geostress onto the model over a long term. During the loading procedure, the collision between two adjacent loading platens is also eliminated by developing a guide frame. This collision phenomenon is induced by the volume shrinkage of the model when compressed in true 3D state. In addition, several accurate measurements, including the optical and grating-based method, are adopted to monitor the small deformation of the model. Hence, the distortion of the model could be accurately measured. In order to validate the performance of this innovative model test system, a 3D geomechanical test was conducted on a simulated deep-buried underground reservoir. The result shows that the radial convergence increases rapidly with the release of the stress in the reservoir. Moreover, the deformation increases with the increase of the gas production rate. This observation is consistence with field observation in petroleum engineering. The system is therefore capable of testing deep-buried engineering structures

  8. Intracerebral cavernous hemangioma after cranial irradiation in childhood. Incidence and risk factors

    International Nuclear Information System (INIS)

    Strenger, V.; Sovinz, P.; Lackner, H.; Dornbusch, H.J.; Moser, A.; Urban, C.; Lingitz, H.; Eder, H.G.

    2008-01-01

    Background and Purpose: Radiotherapy is an integral part of various therapeutic regimens in pediatric and adult oncology. Endocrine dysfunction, neurologic and psychiatric deficits, secondary malignancies and radiation-induced necrosis are well-known possible late effects of cranial irradiation. However, only sporadic cases of radiation-induced cavernous hemangiomas (RICH) have been reported so far. Patients and Methods: Pediatric patients who underwent cranial radiation therapy for malignant diseases between January 1980 and December 2003 were retrospectively analyzed. After the end of therapy they entered a detailed follow-up program. Results: Of 171 patients, eight (three patients with medulloblastoma, three patients with acute lymphoblastic leukemia, and one patient each with ependymoma and craniopharyngioma) developed intracerebral cavernoma 2.9-18.4 years after irradiation representing a cumulative incidence (according to the Kaplan-Meier method) of 2.24%, 3.86%, 4.95%, and 6.74% within 5, 10, 15, and 20 years following radiation therapy, respectively. In patients treated in the first 10 years of life, RICH occurred with shorter latency and significantly more often (p = 0.044) resulting in an even higher cumulative incidence. Conclusion: These findings and previously published cases show that cavernous hemangiomas may occur after irradiation of the brain several years after the end of therapy irrespective of the radiation dose and type of malignancy. Particularly children < 10 years of age at the time of irradiation are at higher risk. Since patients with RICH frequently do not show symptoms but hemorrhage is a possible severe complication, imaging of the central nervous system should be performed routinely for longer follow- ups, particularly in patients who were treated as young children. (orig.)

  9. Intracerebral cavernous hemangioma after cranial irradiation in childhood. Incidence and risk factors

    Energy Technology Data Exchange (ETDEWEB)

    Strenger, V.; Sovinz, P.; Lackner, H.; Dornbusch, H.J.; Moser, A.; Urban, C. [Graz Medical Univ. (Austria). Div. of Pediatric Hematology and Oncology; Lingitz, H. [Graz Medical Univ. (Austria). Dept. of Therapeutic Radiology and Oncology; Eder, H.G. [Graz Medical Univ. (Austria). Dept. of Neurosurgery

    2008-05-15

    Background and Purpose: Radiotherapy is an integral part of various therapeutic regimens in pediatric and adult oncology. Endocrine dysfunction, neurologic and psychiatric deficits, secondary malignancies and radiation-induced necrosis are well-known possible late effects of cranial irradiation. However, only sporadic cases of radiation-induced cavernous hemangiomas (RICH) have been reported so far. Patients and Methods: Pediatric patients who underwent cranial radiation therapy for malignant diseases between January 1980 and December 2003 were retrospectively analyzed. After the end of therapy they entered a detailed follow-up program. Results: Of 171 patients, eight (three patients with medulloblastoma, three patients with acute lymphoblastic leukemia, and one patient each with ependymoma and craniopharyngioma) developed intracerebral cavernoma 2.9-18.4 years after irradiation representing a cumulative incidence (according to the Kaplan-Meier method) of 2.24%, 3.86%, 4.95%, and 6.74% within 5, 10, 15, and 20 years following radiation therapy, respectively. In patients treated in the first 10 years of life, RICH occurred with shorter latency and significantly more often (p = 0.044) resulting in an even higher cumulative incidence. Conclusion: These findings and previously published cases show that cavernous hemangiomas may occur after irradiation of the brain several years after the end of therapy irrespective of the radiation dose and type of malignancy. Particularly children < 10 years of age at the time of irradiation are at higher risk. Since patients with RICH frequently do not show symptoms but hemorrhage is a possible severe complication, imaging of the central nervous system should be performed routinely for longer follow- ups, particularly in patients who were treated as young children. (orig.)

  10. Cavernous malformations of the brainstem presenting in childhood: surgical experience in 40 patients.

    Science.gov (United States)

    Abla, Adib A; Lekovic, Gregory P; Garrett, Mark; Wilson, David A; Nakaji, Peter; Bristol, Ruth; Spetzler, Robert F

    2010-12-01

    Brainstem cavernous malformations (BSCMs) are believed to compose 9% to 35% of all cerebral cavernous malformations, but these lesions have been reported in children in very limited numbers. To review surgical outcomes of pediatric patients with BSCMs treated at 1 institution. We retrospectively analyzed the course of 40 pediatric patients (19 males, 21 females; age range, 10 months to 18.9 years; mean, 12.3 years) who underwent surgery between 1984 and 2009. Age, sex, presenting symptoms, location of lesion, surgical approach, new postoperative deficits, Glasgow Outcome Scale score, recurrences, and resolution of baseline symptoms were recorded. Thirty-nine patients experienced hemorrhage before surgery. Lesion locations included the pons (n=22), midbrain (n=4), midbrain and thalamus (n=4), pontomesencephalic junction (n=3), medulla (n=3), pontomedullary junction (n=3), and cervicomedullary junction (n=1). Mean lesion size was 2.3 cm. Mean length of hospital stay was 10.7 days. The average clinical follow-up was 31.9 months in 36 patients with follow-up after discharge. At last follow-up, 5 patients had experienced symptoms and/or imaging consistent with rehemorrhage, either from a residual that enlarged or true recurrence (5.25% annual rebleed risk per patient after surgery); 2 required reoperation for further resection of cavernoma. Mean Glasgow Outcome Scale score was 4.2 on admission, 4.05 at discharge, and 4.5 at latest follow-up. Preoperative symptoms and deficits improved in 16 patients (40%). New neurological deficits developed in 19 patients (48%) and resolved in 9, leaving 10 patients (25%) with new permanent deficit. Compared with adults, pediatric patients with BCSMs tend to have larger lesions and higher rates of recurrence (regrowth of residual lesion). Given the greater life expectancy of children, surgical treatment seems warranted in those with surgically accessible lesions that have bled. Outcomes were similar to those in our adult series of

  11. Cranial nerve assessment in cavernous sinus tumors with contrast-enhanced 3D fast-imaging employing steady-state acquisition MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Amemiya, Shiori; Aoki, Shigeki; Ohtomo, Kuni [University of Tokyo, Department of Radiology, Graduate School of Medicine, Bunkyo-ku, Tokyo (Japan)

    2009-07-15

    The purpose of this study is to apply contrast-enhanced 3D fast-imaging employing steady-state acquisition (3D-FIESTA) imaging to the evaluation of cranial nerves (CN) in patients with cavernous sinus tumors. Contrast-enhanced 3D-FIESTA images were acquired from ten patients with cavernous sinus tumors with a 3-T unit. In all cases, the trigeminal nerve with tumor involvement was easily identified in the cavernous portions. Although oculomotor and abducens nerves were clearly visualized against the tumor area with intense contrast enhancement, they were hardly identifiable within the area lacking contrast enhancement. The trochlear nerve was visualized in part, but not delineated as a linear structure outside of the lesion. Contrast-enhanced 3D-FIESTA can be useful in the assessment of cranial nerves in and around the cavernous sinus with tumor involvement. (orig.)

  12. Post-irradiation lumbosacral radiculopathy associated with multiple cavernous malformations of the cauda equina: Case report and review of the literature

    OpenAIRE

    Drazin, Doniel; Kappel, Ari; Withrow, Stefan; Perry, Tiffany; Chu, Ray; Phuphanich, Surasak

    2017-01-01

    Background: Multiple radiation-induced cavernous malformations of the cauda equina are extremely rare. A review of the literature suggested that the post-irradiation lumbosacral radiculopathy in our patient was most likely associated with a diagnosis of multiple radiation-induced cavernous malformations of the cauda equina. Case Description: A 76-year-old man with a remote history of abdominal radiation therapy presented with a 6-month history of progressively worsening right foot drop and...

  13. Study of the ventilation at ATLAS cavern UX15 air velocity and temperature around the muon chambers

    CERN Document Server

    Vigo-Castellví, E

    2000-01-01

    The Muon Chambers of ATLAS detector cannot work under temperature differences between two opposed faces above 3 K. In addition, a low velocity of the air around the Muon Chambers is essential to avoid vibration problems. The CV group at the ST division is involved in an airflow simulation inside UX15 cavern to check air temperature and velocity profiles around the ATLAS Muon Chambers. In this paper, the status and the content of the performed theoretical studies will be explained. Three simulation models, which helped to understand the Muon Spectrometer thermal environment and the efficiency of the ventilation system at ATLAS cavern, will be presented. Besides, it will be shown how these studies support the proposal of a deeper individual Muon Chamber study.

  14. Novel Optical Methods for Identification, Imaging, and Preservation of the Cavernous Nerves Responsible for Penile Erections during Prostate Cancer Surgery

    Science.gov (United States)

    2010-03-01

    pr obe for del ivering a s mall, c ollimated, flat-top l aser beam for uniform cavernous nerve stimulation. A direct comparison of the magnitude and...scanning a distance of 25 mm for side-firing delivery. The motorized stage was connected to a PC via USB connections and operated with Labview...Edmund Optics, Barrington, NJ) with custom gold coating (International Micro Photonix, Tewksbury, MA). The optical fiber was inserted into a glass

  15. Intravenous Infusion of Bone Marrow–Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats

    OpenAIRE

    Yohei Matsuda, MD; Masanori Sasaki, MD, PhD; Yuko Kataoka-Sasaki, MD, PhD; Akio Takayanagi, MD, PhD; Ko Kobayashi, MD, PhD; Shinichi Oka, MD, PhD; Masahito Nakazaki, MD, PhD; Naoya Masumori, MD, PhD; Jeffery D. Kocsis, PhD; Osamu Honmou, MD, PhD

    2018-01-01

    Introduction: Intravenous preload (delivered before cavernous nerve [CN] injury) of bone marrow–derived mesenchymal stem cells (MSCs) can prevent or decrease postoperative erectile dysfunction (J Sex Med 2015;12:1713–1721). In the present study, the potential therapeutic effects of intravenously administered MSCs on postoperative erectile dysfunction were evaluated in a rat model of CN injury. Methods: Male Sprague-Dawley rats were randomized into 2 groups after electric CN injury. Intrave...

  16. Unilateral duplicated abducens nerve coursing through both the sphenopetroclival venous gulf and cavernous sinus: a case report.

    Science.gov (United States)

    Coquet, Thomas; Lefranc, Michel; Chenin, Louis; Foulon, Pascal; Havet, Éric; Peltier, Johann

    2018-03-15

    In this anatomy report, we describe the first case of abducens nerve duplication limited to the sphenopetroclival venous gulf and the cavernous sinus. The objective point of division of the two duplicated roots was localized at the gulfar face of the dural porus, just distal to the unique cisternal trunk of the abducens nerve, as it pierced the petroclival dural mater. In the gulfar segment, both roots traveled through a variant of Dorello's canal called the "petrosphenoidal canal" and remained separated through the posterior half of the cavernous sinus. Both roots finally fused in the anterior half of the cavernous sinus to innervate the lateral rectus muscle as a single trunk. Although many variants of the abducens nerve have been reported over the recent decades, this anatomic variation has never been previously described and enriches the continuum of abducens nerve variations reported in the literature data. Awareness of this variation is crucial for neurosurgeons, especially during clival or petrosal surgical approaches used for resection of skull base chordomas.

  17. Performance Study of Salt Cavern Air Storage Based Non-Supplementary Fired Compressed Air Energy Storage System

    Science.gov (United States)

    Chen, Xiaotao; Song, Jie; Liang, Lixiao; Si, Yang; Wang, Le; Xue, Xiaodai

    2017-10-01

    Large-scale energy storage system (ESS) plays an important role in the planning and operation of smart grid and energy internet. Compressed air energy storage (CAES) is one of promising large-scale energy storage techniques. However, the high cost of the storage of compressed air and the low capacity remain to be solved. This paper proposes a novel non-supplementary fired compressed air energy storage system (NSF-CAES) based on salt cavern air storage to address the issues of air storage and the efficiency of CAES. Operating mechanisms of the proposed NSF-CAES are analysed based on thermodynamics principle. Key factors which has impact on the system storage efficiency are thoroughly explored. The energy storage efficiency of the proposed NSF-CAES system can be improved by reducing the maximum working pressure of the salt cavern and improving inlet air pressure of the turbine. Simulation results show that the electric-to-electric conversion efficiency of the proposed NSF-CAES can reach 63.29% with a maximum salt cavern working pressure of 9.5 MPa and 9 MPa inlet air pressure of the turbine, which is higher than the current commercial CAES plants.

  18. Principle of gas storage in salt caverns; Principe du stockage de gaz en cavites creusees dans le sel

    Energy Technology Data Exchange (ETDEWEB)

    Durup, J.G. [Mining Research Institute, CA (United States)]|[Gaz de France (GDF), 75 - Paris (France)

    2001-08-15

    The principle of the exploitation of a gas storage cavity is analogue to the one of a cylinder of compressed gas. Such a reservoir has remarkable dimensions with a volume of several thousands of m{sup 3}, a height of few hundred meters and a diameter of about 100 m. The mechanical resistance with respect to the gas pressure is ensured by the 'pre-stress' corresponding to the weight of the geologic strata. Salt (halite) is the ideal material for the digging out of such facilities because of its excellent tightness, its solubility in water (allowing the dissolution digging technique), and its good mechanical resistance. Natural gas storage is in general performed in natural porous and permeable environments, like depleted hydrocarbon fields or aquifers. The storage in salt caverns has the advantage of allowing important emission flow rates with respect to the quantities of immobilized gases. In some Northern Europe countries, like Germany, the salt deposits are well developed and abundant, in particular near the North Sea and its important natural gas fields. In France, there exists 3 gas storage sites in salt caverns, with about 40 cavities as a whole. This document briefly presents the main elements of the gas storage technique in salt caverns: characteristics and geology of salt deposits, geo-technique, wells, dissolution digging, gas injection and exploitation. (J.S.)

  19. Genetically diagnosed Birt-Hogg-Dubé syndrome and familial cerebral cavernous malformations in the same individual: a case report.

    Science.gov (United States)

    Whitworth, James; Stausbøl-Grøn, Brian; Skytte, Anne-Bine

    2017-01-01

    When faced with an unusual clinical feature in a patient with a Mendelian disorder, the clinician may entertain the possibilities of either the feature representing a novel manifestation of that disorder or the co-existence of a different inherited condition. Here we describe an individual with a submandibular oncocytoma, pulmonary bullae and renal cysts as well as multiple cerebral cavernous malformations and haemangiomas. Genetic investigations revealed constitutional mutations in FLCN, associated with Birt-Hogg-Dubé syndrome (BHD) and CCM2, associated with familial cerebral cavernous malformation. Intracranial vascular pathologies (but not cerebral cavernous malformation) have recently been described in a number of individuals with BHD (Kapoor et al. in Fam Cancer 14:595-597, 10.1007/s10689-015-9807-y , 2015) but it is not yet clear whether they represent a genuine part of that conditions' phenotypic spectrum. We suggest that in such instances of potentially novel clinical features, more extensive genetic testing to consider co-existing conditions should be considered where available. The increased use of next generation sequencing applications in diagnostic settings is likely to lead more cases such as this being revealed.

  20. The cost-effect analysis of interventional and surgical therapy for symptomatic cavernous hemangioma of liver

    International Nuclear Information System (INIS)

    Zeng Qingle; Chen Yong; Zhao Jianbo; Zhang Kewei; Li Yanhao

    2009-01-01

    Objective: Through comparing the damage of hepatic function, occurrence of complications, hospitalization days and medical expense between PLE-IASE therapy and surgical management for symptomatic cavernous hemangioma of liver to provide theoretical guidance in selecting proper treatment for this disease. Methods: One hundred and forty-seven patients were randomly divided into PLE-IASE embolization group (n=89) and surgery group (n=58). Before and 3-7 days after the treatment liver function, including ALT, AST, TBIL, IBIL, TP and ALB, was tested in all patients. The differences in the liver function data between two groups were statistically analyzed. The hospitalization days and medical expense of two groups were also recorded and compared. The complication occurrence of both short-term and long-term was observed, and the results in two groups were compared. Results: No significant difference in liver function was found between two groups before the treatment. After the treatment, the increase of ALT, AST and TBIL in embolization group was significantly lower than that in surgery group, with P value being 0.000, 0.014 and 0.004 respectively. The decrease of TP and ALB in embolization group was also lower than that in surgery group (both P=0.000). During hospitalization, complication occurred in one case in embolization group and in 12 cases in surgery group of which mild complication was seen in 10 and serious complication in 2. No treatment-related complications occurred in long-term observation in neither of the groups. The complication occurrence in embolization group and surgery group was 1.1% and 20.7% respectively, with a significant difference between two groups (P=0.000). The mean hospitalization days and medical expense in embolization group were (8.0 ± 3.5) days and (13 612.7 ± 5 860.5) respectively, while in surgery group were(19.0 ± 5.0) days and (26 335.6 ± 8 314.0) respectively, with significant difference (both P=0.000). Conclusion: For the

  1. The occurrence and proposed significance of Schnabel cavernous degeneration in uveal melanoma.

    Science.gov (United States)

    Kanavi, Mozhgan Rezaei; Azari, Amir A; Potter, Heather D; Lee, Vivian; Albert, Daniel M

    2014-05-01

    Schnabel cavernous degeneration (SCD) has been observed in eyes with uveal melanoma (UM), but, to our knowledge, a definitive study establishing the association between SCD and UM has not been conducted. To explore an association between SCD and UM. A historical cohort analysis was performed using histologic slides and related clinical records of cases from the Collaborative Ocular Melanoma Study and Eye Pathology Laboratory at the University of Wisconsin, including 1985 UM eyes, 517 eye bank eyes, and 155 enucleated glaucomatous eyes. The prevalence of SCD was calculated and compared between each group; subgroup analysis was also conducted of eyes with and without SCD for the prevalence of glaucoma. Schnabel cavernous degeneration was seen in 17 (0.9%) UM eyes, 9 (1.7%) eye bank eyes, and 2 (1.3%) enucleated glaucomatous eyes. No difference was detected between the prevalence of SCD in UM eyes and eye bank eyes (odds ratio [OR], 0.49; 95% CI, 0.22-1.10) or enucleated glaucomatous eyes (OR, 0.66; 95% CI, 0.15-2.89). Subgroup analysis, performed on 421 UM eyes, provided sufficient clinical information to definitively establish the presence or absence of glaucoma. Of the 95 (22.6%) eyes with glaucoma, 11 (11.6%) revealed histopathologic evidence of SCD. Compared with enucleated end-stage glaucoma eyes, this represents a 10-fold increase in SCD in UM eyes with glaucoma (OR, 10.10; 95% CI, 2.17-46.26). The prevalence of glaucoma in UM eyes with SCD, however, was respectively 7- and 15-fold higher than the prevalence of glaucoma in SCD-negative UM eyes (OR, 6.98; 95% CI, 2.51-19.43) and SCD-positive eye bank eyes (OR, 14.67; 95% CI, 1.46-146.97). Although an association between SCD and UM was not confirmed, subgroup analysis did reveal an increased incidence of SCD in eyes with both UM and glaucoma. This suggests that the occurrence of glaucoma may increase the risk of SCD in eyes with UM.

  2. Coexistence of extra-axial cavernous malformation and cerebellar developmental venous anomaly in the cerebellopontine angle.

    Science.gov (United States)

    Wu, Bo; Liu, Weidong; Zhao, Yuan

    2012-01-01

    The coexistence of cavernous malformations (CMs) and developmental venous anomalies (DVAs) in the cerebellopontine angle (CPA) is exceedingly rare. To the authors' knowledge, only one case of CPA CM with concurrence of a neighboring DVA has been reported to date. The authors presented such vascular malformations in a 36-year-old man with progressive CPA syndrome during the course of six weeks. Preoperative neuroimaging suggested the diagnosis of an extra-axial hemorrhagic lesion in the CPA cistern with a cerebellar DVA in the close vicinity. The lesion was totally removed with the DVA untouched and was confirmed to be extra-axial in intimate contact with only the VII-VIII complex and the draining veins of DVA. Pathology revealed a CM. The patient underwent partial improvement in neurological function postoperatively. The radiographic follow-up at one year revealed no recurrence. CMs should be considered in the differential diagnosis of any extra-axial hemorrhagic mass, especially with a DVA in the proximity. The coexistence of CM and DVA in CPA, although maybe just a coincidence, suggests the possibility of a new subtype of extra-axial CPA CM secondary to a preexisting DVA. A long-term follow-up is justified in discovering the potential mechanism and biology of such uncommon vascular malformations. Copyright © 2012 Elsevier Inc. All rights reserved.

  3. Structure and vascular function of MEKK3–cerebral cavernous malformations 2 complex

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Oriana S. [Yale Univ., New Haven, CT (United States); Deng, Hanqiang [Shanghai Jiao Tong Univ. School of Medicine (SJTU-SM), Shanghai (China); Liu, Dou [Yale Univ. School of Medicine, New Haven, CT (United States); Zhang, Ya [Yale Univ. School of Medicine, New Haven, CT (United States); Wei, Rong [Shanghai Jiao Tong Univ. School of Medicine (SJTU-SM), Shanghai (China); Deng, Yong [Yale Univ. School of Medicine, New Haven, CT (United States); Zhang, Fan [Yale Univ. School of Medicine, New Haven, CT (United States); Louvi, Angeliki [Yale Univ. School of Medicine, New Haven, CT (United States); Turk, Benjamin E. [Yale Univ., New Haven, CT (United States); Boggon, Titus J. [Yale Univ., New Haven, CT (United States); Su, Bing [Shanghai Jiao Tong Univ. School of Medicine (SJTU-SM), Shanghai (China)

    2015-08-03

    Cerebral cavernous malformations 2 (CCM2) loss is associated with the familial form of CCM disease. The protein kinase MEKK3 (MAP3K3) is essential for embryonic angiogenesis in mice and interacts physically with CCM2, but how this interaction is mediated and its relevance to cerebral vasculature are unknown. Here we report that Mekk3 plays an intrinsic role in embryonic vascular development. Inducible endothelial Mekk3 knockout in neonatal mice is lethal due to multiple intracranial haemorrhages and brain blood vessels leakage. We discover direct interaction between CCM2 harmonin homology domain (HHD) and the N terminus of MEKK3, and determine a 2.35 Å cocrystal structure. We find Mekk3 deficiency impairs neurovascular integrity, which is partially dependent on Rho–ROCK signalling, and that disruption of MEKK3:CCM2 interaction leads to similar neurovascular leakage. We conclude that CCM2:MEKK3-mediated regulation of Rho signalling is required for maintenance of neurovascular integrity, unravelling a mechanism by which CCM2 loss leads to disease.

  4. Discovery Mondays: 'The civil engineering genius of the 100-metre deep underground caverns'

    CERN Multimedia

    2004-01-01

    CERN is first and foremost a place where physicists study particle collisions. But to be able to observe the infinitely small, they need huge pieces of equipment, the accelerators and detectors, whose construction, some 100 metres below the earth's surface calls on the services of other fascinating disciplines. Take civil engineering, for example. For the construction of the LHC some 420 000 cubic metres of rock have had to be excavated for the 6500 metres of tunnel, 6 new shafts and 32 underground chambers and caverns. To avoid disrupting other experiments in progress, the work on these exceptional structures has had to be done without creating vibrations. The ATLAS experiment hall, a huge cathedral-like structure 100 metres below ground, is another mind-blowing feat of civil engineering. Its construction involved the use of ground-breaking technology, such as the system for suspending the ceiling put in place during the excavation work. At the next Discovery Monday, the specialists responsible for...

  5. Surgical Management of Cavernous Malformations Presenting with Drug-Resistant Epilepsy

    Science.gov (United States)

    Alonso-Vanegas, Mario Arturo; Cisneros-Franco, José M.; Otsuki, Taisuke

    2011-01-01

    Cerebral cavernous malformations (CMs) are dynamic lesions characterized by continuous size changes and repeated bleeding. When involving cortical tissue, CMs pose a significant risk for the development of drug-resistant epilepsy, which is thought to be result of an altered neuronal network caused by the lesion itself and its blood degradation products. Preoperative evaluation should comprise a complete seizure history, neurological examination, epilepsy-oriented MRI, EEG, video-EEG, completed with SPECT, PET, functional MRI, and/or invasive monitoring as needed. Radiosurgery shows variable rates of seizure freedom and a high incidence of complications, thus microsurgical resection remains the optimal treatment for CMs presenting with drug-resistant epilepsy. Two thirds of patients reach Engel I class at 3-year follow-up, regardless of lobar location. Those with secondarily generalized seizures, a higher seizure frequency, and generalized abnormalities on preoperative or postoperative EEG, show poorer outcomes, while factors such as gender, duration of epilepsy, lesion size, age, bleeding at the time of surgery, do not correlate consistently with seizure outcome. Electrocorticography and a meticulous removal of all cortical hemosiderin – beyond pure lesionectomy – reduce the risk of symptomatic recurrences. PMID:22319505

  6. Surrounding rock deformation analysis of underground caverns with multi-body finite element method

    Directory of Open Access Journals (Sweden)

    Wan Jin Liang

    2009-09-01

    Full Text Available Discontinuous deformation problems are common in rock engineering. Numerical analysis methods based on system models of the discrete body can better solve these problems. One of the most effective solutions is discontinuous deformation analysis (DDA method, but the DDA method brings about rock embedding problems when it uses the strain assumption in elastic deformation and adopts virtual springs to simulate the contact problems. The multi-body finite element method (FEM proposed in this paper can solve the problems of contact and deformation of blocks very well because it integrates the FEM and multi-body system dynamics theory. It is therefore a complete method for solving discontinuous deformation problems through balance equations of the contact surface and for simulating the displacement of whole blocks. In this study, this method was successfully used for deformation analysis of underground caverns in stratified rock. The simulation results indicate that the multi-body FEM can show contact forces and the stress states on contact surfaces better than DDA, and that the results calculated with the multi-body FEM are more consistent with engineering practice than those calculated with DDA method.

  7. The far lateral transpontomedullary sulcus approach to pontine cavernous malformations: technical report and surgical results.

    Science.gov (United States)

    Abla, Adib A; Benet, Arnau; Lawton, Michael T

    2014-09-01

    Pontine cavernous malformations (CMs) located on a peripheral pontine surface or the fourth ventricular floor are resectable lesions, but those deep within the pons away from a pial surface are typically observed. However, the anterior bulge of the pons formed by the brachium pontis creates a unique entry point for access to deep pontine lesions from below, working upward through the pontomedullary sulcus. We developed a transpontomedullary sulcus (TPMS) approach to these lesions. The TPMS approach used the far lateral craniotomy and upper vagoaccessory triangle to define the surgical corridor. The entry point was above the olive, lateral to the pyramidal tracts and cranial nerve (CN) VI, above the preolivary sulcus and CN XII, and medial to CNs VII and VIII and CNs IX through XI. Four patients underwent this approach. All presented with hemorrhage and CN VI palsies. All pontine CMs were resected completely. Three patients were improved or unchanged, with good outcomes (modified Rankin Scale score ≤2) in all patients. The central pons remains difficult territory to access, and new surgical corridors are needed. The bulging underbelly of the pons allows access to pontine lesions deep to the pial surface from below. The far lateral TPMS approach is a novel and more direct alternative to the retrosigmoid transmiddle cerebellar peduncle approach. Unlike the retrosigmoid approach, the TPMS approach requires minimal parenchymal transgression and uses a brainstem entry point medial to most lower CNs. Favorable results demonstrate the feasibility of resecting pontine CMs that might have been previously deemed unresectable.

  8. Possible role of the cavernous sinus veins in cerebrospinal fluid absorption

    Directory of Open Access Journals (Sweden)

    Koh Lena

    2007-04-01

    Full Text Available Abstract The purpose of this investigation was to enhance our understanding of cerebrospinal fluid (CSF absorption pathways. To achieve this, Microfil (a coloured silastic material was infused into the subarachnoid space (cisterna magna of sheep post mortem, and the relevant tissues examined macroscopically and microscopically. The Microfil was taken up by an extensive network of extracranial lymphatic vessels in the olfactory turbinates. In addition however, Microfil also passed consistently through the dura at the base of the brain. Microfil was noted in the spaces surrounding the venous network that comprises the cavernous sinus, in the adventitia of the internal carotid arteries and adjacent to the pituitary gland. Additionally, Microfil was observed within the endoneurial spaces of the trigeminal nerve and in lymphatic vessels emerging from the epineurium of the nerve. These results suggest several unconventional pathways by which CSF may be removed from the subarachnoid space. The movement of CSF to locations external to the cranium via these routes may lead to its absorption into veins and lymphatics outside of the skull. The physiological importance of these pathways requires further investigation.

  9. Cavernous angioma after chemotherapy for desmoplastic/nodular medulloblastoma associated with anhidrotic ectodermal dysplasia.

    Science.gov (United States)

    Yamasaki, Fumiyuki; Takayasu, Takeshi; Nosaka, Ryo; Kawaguchi, Hiroshi; Sugiyama, Kazuhiko; Kobayashi, Masao; Kurisu, Kaoru

    2016-02-01

    While cavernous angioma (CVA) after cranial irradiation has been documented, its development after high-dose chemotherapy with autologous peripheral blood stem cell transplantation (PBSCT) has not. We present a patient with desmoplastic/nodular medulloblastoma (DNMB) associated with anhidrotic ectodermal dysplasia (AED) who developed CVA 2 years after high-dose chemotherapy and PBSCT. A 1-year-old boy with ingravescent vomiting was admitted to our institute. He presented with a large head, a depressed nasal bridge, low-set ears, thick lips with peg-shaped teeth, hypohidrosis, sparse hair, thin atrophic skin, scaly dermatitis with frontal bossing, and a bulging anterior fontanel. Neuroradiological examination revealed multiple cerebellar masses with heterogeneous enhancement and speckled calcifications and severe obstructive hydrocephalus. The histological diagnosis of surgical specimens was DNMB, and he underwent postoperative multiple-drug chemotherapy with autologous PBSCT. The outcome was favorable and he did not undergo radiotherapy. After 2 years, intracranial hemorrhage was detected at his regular radiological check-up and he again underwent surgery. The histological diagnosis was CVA. To our knowledge, this is the first report of AED-associated DNMB and CVA.

  10. Installation of the Liquid Argon Calorimater Barrel in the ATLAS Experimental Cavern

    CERN Multimedia

    Vandoni, G.

    On the 27th of October, the Liquid Argon Barrel cryostat was transported from Building 180 to point 1. The next day, the Barrel was lowered into the cavern, and was placed on jacks close to its final position inside the completed lower half of the Tile calorimeter. After a day of precise adjustment, it was resting within a few millimetres of its nominal final position, waiting for the upper half of the Tile calorimeter to be installed. Tight requests had been issued by the Liquid Argon collaboration for the whole transport. It was foreseen that the cryostat should not see any acceleration larger than 0.15g along its axis, 0.08g transversally and 0.3g in the vertical direction. In addition, no acceleration higher than 0.03g (or even 0.003g for permanent oscillation) would be allowed at 20Hz, to avoid the risk of damaging the absorbers at this spontaneous vibration frequency. The difficulty would arise when coping these demands with the tortuous route, its slopes and curbs, vibration transmission from the engi...

  11. Efficacy of Cone Beam Computed Tomography in Treating Cavernous Sinus Dural Arteriovenous Fistula.

    Science.gov (United States)

    Kadooka, Keisuke; Tanaka, Michihiro; Sakata, Yoshinori; Ideguchi, Minoru; Inaba, Maki; Hadeishi, Hiromu

    2018-01-01

    Exact identification of feeding arteries, shunt points, and draining veins is essential in treating cavernous sinus dural arteriovenous fistula (CS dAVF). In addition to digital subtraction angiography (DSA) and 3-dimensional rotational angiography (3DRA), high-resolution cone beam computed tomography (CBCT; especially 80-kv high-resolution cone beam computed tomography) have been performed in recent years. We evaluated the efficacy of CBCT in treating CS dAVF. Eight CS dAVFs were treated with endovascular embolization between January 2013 and December 2016. We retrospectively examined these cases regarding information from DSA, 3DRA, and CBCT with contrast medium. Although all procedures can evaluate feeding arteries, shunt points, and draining veins, CBCT can provide the best definition of feeders and their course through the bony structures and the compartment of CS. Therefore, CBCT with placed microcatheter in the CS can reveal whether the microcatheter is set at the appropriate compartment to be embolized. The efficacy of CBCT in treating dAVF is illustrating the relationships among the bony structures and feeders, compartment of CS, and the position of the microcatheter. Detailed information obtained with CBCT can lead to fewer complications and more effective treatment. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Intractable Posterior Epistaxis due to a Spontaneous Low-Flow Carotid-Cavernous Sinus Fistula: A Case Report and a Review of the Literature

    Directory of Open Access Journals (Sweden)

    A. Giotakis

    2015-01-01

    Full Text Available We report a case of a 90-year-old patient with intractable posterior epistaxis presenting as the only symptom of a nontraumatic low-flow carotid-cavernous sinus fistula. Purpose of this case report is to introduce low-flow carotid-cavernous sinus fistula in the differential diagnosis of intractable posterior epistaxis. We provide a literature review for the sequence of actions for the confrontation of posterior epistaxis. We also emphasize the significance of the radiological diagnostic and therapeutic procedures in the management of posterior epistaxis due to pathology of the cavernous sinus. The gold-standard diagnostic procedure of carotid-cavernous sinus fistula is digital subtraction angiography (DSA. DSA with coils is also the state-of-the-art therapy. By failure of DSA, neurosurgery or stereotactic radiosurgery (SRS may be used as alternatives. SRS may also be used as enhancement procedure of the DSA. Considering the prognosis of a successfully closed carotid-cavernous sinus fistula, recanalization occurs only in a minority of patients. Close follow-up is advised.

  13. Dsa examination and diagnosis of arteriovenous shunts in hepatic cavernous hemangiomas of adults

    International Nuclear Information System (INIS)

    Ouyang Yong; Ouyang Xuehui; Gu Subin; Zhou Qunhui

    2000-01-01

    Objective: To correct the misunderstanding that arteriovenous shunts (AVS) are rarely found in adult cavernous hemangiomas of the liver (CHL) and to increase its diagnosis rate by DSA. Methods: DSA examination and DSA images of thirty adults with definitely diagnostic CHL and without evidence of other hepatic diseases and hepatic injury were analyzed retrospectively. X-ray films of 21 cases with AVS taken immediately after transcatheter arterial embolization using lipiodol (L-TAE) were compared with the corresponding DSA images to check up those AVS opacified in DSA by observing sediment and distribution of iodized oil injected. Results: Definite diagnosis of AVS by DSA were obtained in 22 cases of this series (73%). All the AVS were located in the peritumoral parenchyma and appeared as parallel track sign, and early opacification of small draining veins, etc. during arterial phase of DSA. X-ray films taken immediately after L-TAE in 21 of 22 cases with AVS showed that few portal radicles or draining veins were refilled by iodized oil through incompletely occluded shunts in 11 cases, and no any vein was refilled by iodized oil resulted from complete occlusion of the present AVS in 10. No definite AVS was found in the other 8 cases of this series, and in 6 of them improper imaging factors of DSA were used. Conclusion: This study serves to emphasize that AVS is not a diagnosis of hepatic malignancy, but is frequently seen in the commonly benign CHL of adults. Proper imaging factors of DSA and superior images can be helpful to opacify small AVS of CHL. The formation of AVS in CHL may be closely related to the pathological changes of peritumoral parenchyma, however, its mechanism must be further studied

  14. Culturable microbial diversity and the impact of tourism in Kartchner Caverns, Arizona.

    Science.gov (United States)

    Ikner, Luisa A; Toomey, Rickard S; Nolan, Ginger; Neilson, Julia W; Pryor, Barry M; Maier, Raina M

    2007-01-01

    Kartchner Caverns in Benson, AZ, was opened for tourism in 1999 after a careful development protocol that was designed to maintain predevelopment conditions. As a part of an ongoing effort to determine the impact of humans on this limestone cave, samples were collected from cave rock surfaces along the cave trail traveled daily by tour groups (200,000 visitors year-1) and compared to samples taken from areas designated as having medium (30-40 visitors year-1) and low (2-3 visitors year-1) levels of human exposure. Samples were also taken from fiberglass moldings installed during cave development. Culturable bacteria were recovered from these samples and 90 unique isolates were identified by using 16S rRNA polymerase chain reaction and sequencing. Diversity generally decreased as human impact increased leading to the isolation of 32, 27, and 22 strains from the low, medium, and high impact areas, respectively. The degree of human impact was also reflected in the phylogeny of the isolates recovered. Although most isolates fell into one of three phyla: Actinobacteria, Firmicutes, or Proteobacteria, the Proteobacteria were most abundant along the cave trail (77% of the isolates), while Firmicutes predominated in the low (66%) and medium (52%) impact areas. Although the abundance of Proteobacteria along the cave trail seems to include microbes of environmental rather than of anthropogenic origin, it is likely that their presence is a consequence of increased organic matter availability due to lint and other organics brought in by cave visitors. Monitoring of the cave is still in progress to determine whether these bacterial community changes may impact the future development of cave formations.

  15. Parametric color coding of digital subtraction angiography in the evaluation of carotid cavernous fistulas.

    Science.gov (United States)

    Gölitz, P; Struffert, T; Lücking, H; Rösch, J; Knossalla, F; Ganslandt, O; Deuerling-Zheng, Y; Doerfler, A

    2013-06-01

    Angiographic assessment of carotid cavernous fistulas (CCFs) can be complex. Our purpose was to examine whether the use of parametric color coding in the postprocessing of DSA series is advantageous in the evaluation of CCFs. We enrolled 16 patients with angiographically proven CCFs. Endovascular treatment was performed in 14 cases. For postprocessing of digital subtraction angiography (DSA) series, a newly implemented algorithm of parametric color coding was used, turning sequential images of two-dimensional (2D)-DSA series into a single color-coded image. Angiographic data of initial, interventional, and postinterventional 2D-DSA series were compared with color-coded images. Whether parametric color coding could facilitate evaluation of fistula architecture and provide a more precise estimation of fistula venous drainage patterns as well as whether flow analysis could reveal objective changes during and after treatment were investigated. In 56 % of the cases, parametric color coding was observed to facilitate visualization of fistula angioarchitecture. Estimation of fistula drainage flow patterns was considered to be improved in 31 % of the cases. For assessment of hemodynamic changes during and after treatment, parametric color coding was assumed to be helpful in 21 % of the cases, especially because revealing flow changes that were not visible on 2D-DSA series were now visible. Parametric color coding is a fast application tool that might provide additional support in the angiographic evaluation of CCFs. Visualization of complex fistula architecture could be facilitated, and flow analysis might improve assessment of venous drainage patterns, thereby increasing overall diagnostic confidence. During and after treatment, hemodynamic changes that were not visible on 2D-DSA series could now be depicted.

  16. The effect of cavernous nerve traction on erectile function in rats.

    Directory of Open Access Journals (Sweden)

    Hao Li

    Full Text Available We performed this study to evaluate the effect of cavernous nerve (CN traction on erectile function in rats. Thirty-two 8- week-old Sprague-Dawley rats were divided into four groups: control, 1-minute CN traction, 2-minute CN traction, and 2-minute CN crush. CN traction was performed using a glass hook with a tensile force of 0.2 Newton. One month later, the mean arterial pressure (MAP and intracavernosal pressure (ICP in response to CN stimulation were measured to assess erectile function. The penis and major pelvic ganglion (MPG were harvested to explore the expression of neuronal nitric oxide synthase (nNOS and neurofilament, fibrosis and apoptosis. The ICP/MAP ratio was reduced in the 2-minute CN traction group compared with the control group (P < 0.05. The ICP/MAP ratio in the CN crush group was lower than in the other three groups (P < 0.05, for each. Expression of nNOS in both MPG and dorsal penile nerve was lower in the CN traction group than in the control group, but was higher than in the CN crush group (P < 0.05. Nerve fiber number in the dorsal penile nerve was reduced by 2-minute CN traction (P < 0.05. The ratios of collagen to smooth muscle content and the apoptosis were both increased the in 2-minute CN traction group compared with the control group (P < 0.05. The findings indicate that CN traction is an effective CN injury model and the injury it caused is relatively mild compared with the CN crush model.

  17. A new strategic neurosurgical planning tool for brainstem cavernous malformations using interactive computer graphics with multimodal fusion images.

    Science.gov (United States)

    Kin, Taichi; Nakatomi, Hirofumi; Shojima, Masaaki; Tanaka, Minoru; Ino, Kenji; Mori, Harushi; Kunimatsu, Akira; Oyama, Hiroshi; Saito, Nobuhito

    2012-07-01

    In this study, the authors used preoperative simulation employing 3D computer graphics (interactive computer graphics) to fuse all imaging data for brainstem cavernous malformations. The authors evaluated whether interactive computer graphics or 2D imaging correlated better with the actual operative field, particularly in identifying a developmental venous anomaly (DVA). The study population consisted of 10 patients scheduled for surgical treatment of brainstem cavernous malformations. Data from preoperative imaging (MRI, CT, and 3D rotational angiography) were automatically fused using a normalized mutual information method, and then reconstructed by a hybrid method combining surface rendering and volume rendering methods. With surface rendering, multimodality and multithreshold techniques for 1 tissue were applied. The completed interactive computer graphics were used for simulation of surgical approaches and assumed surgical fields. Preoperative diagnostic rates for a DVA associated with brainstem cavernous malformation were compared between conventional 2D imaging and interactive computer graphics employing receiver operating characteristic (ROC) analysis. The time required for reconstruction of 3D images was 3-6 hours for interactive computer graphics. Observation in interactive mode required approximately 15 minutes. Detailed anatomical information for operative procedures, from the craniotomy to microsurgical operations, could be visualized and simulated three-dimensionally as 1 computer graphic using interactive computer graphics. Virtual surgical views were consistent with actual operative views. This technique was very useful for examining various surgical approaches. Mean (±SEM) area under the ROC curve for rate of DVA diagnosis was significantly better for interactive computer graphics (1.000±0.000) than for 2D imaging (0.766±0.091; pcomputer graphics than with 2D images. Interactive computer graphics was also useful in helping to plan the surgical

  18. Cavernous hemangioma of the bladder in a child of 6 years and 11 months

    OpenAIRE

    N. I. Zryachkin; G. I. Chebotareva; S. A. Khmilevskaya; T. N. Buchkova; M. A. Bezverkhova

    2017-01-01

    We analyze a clinical case of the patient at the age of 6 years and 11 months with a cavernous hemangioma of the bladder. The disease manifested with isolated macrohaematuria. During the diagnostic assessment by 3D-ultrasound examination of the urinary tract with tight bladder filling, a mass with tuberous shape and echonegative areas inside was visualized on the left bladder wall close to its anterior surface, while external bladder contours were unchanged. Color Doppler mapping showed some ...

  19. Ehlers-Danlos syndrome type IV and recurrent carotid-cavernous fistula: review of the literature, endovascular approach, technique and difficulties

    Energy Technology Data Exchange (ETDEWEB)

    Desal, H.A.; Toulgoat, F.; Raoul, S.; Guillon, B.; Bommard, S.; Naudou-Giron, E.; Auffary-Calvier, E.; Kersaint-Gilly, A. de [Department of Neuroradiology, Laennec Hospital, University of Nantes (France); 1

    2005-04-01

    We report the follow-up of a previously published case (Forlodou et al. Neuroradiology 38:595-597, 1996) of carotido-cavernous fistulas (CCFs) in a patient presenting with type IV Ehlers-Danlos syndrome (EDS 4) that were successfully treated twice by an endovascular approach. Initial treatment with a detachable balloon was in 1994 for a right CCF, and, 8 years later, a left CCF was treated by selective transarterial occlusion of the cavernous sinus with coils. Unfortunately, the patient suffered from a spontaneous post-operative intracranial haemorrhage in the left hemisphere and died. Review of the literature, technical considerations for bilateral CCF and complication are discussed.

  20. JACoW Virtual control commissioning for a large critical ventilation system: The CMS cavern use case

    CERN Document Server

    Booth, William; Bradu, Benjamin; Sourisseau, Samuel

    2018-01-01

    The current cavern ventilation control system of the CMS experiment at CERN is based on components which are already obsolete: the SCADA system, or close to the end of life: the PLCs. The control system is going to be upgraded during the LHC Long Shutdown 2 (2019-2020) and will be based on the CERN industrial control standard: UNICOS employing WinCC OA as SCADA and Schneider PLCs. Due to the critical nature of the CMS ventilation installation and the short allowed downtime, the approach was to design an environment based on the virtual commissioning of the new control. This solution uses a first principles model of the ventilation system to simulate the real process. The model was developed with the modelling and simulation software EcosimPro. In addition, the current control application of the cavern ventilation will also be re-engineered as it is not completely satisfactory in some transients where many sequences are performed manually and some pressure fluctuations observed could potentially cause issues t...

  1. Costs for off-site disposal of nonhazardous oil field wastes: Salt caverns versus other disposal methods

    Energy Technology Data Exchange (ETDEWEB)

    Veil, J.A.

    1997-09-01

    According to an American Petroleum Institute production waste survey reported on by P.G. Wakim in 1987 and 1988, the exploration and production segment of the US oil and gas industry generated more than 360 million barrels (bbl) of drilling wastes, more than 20 billion bbl of produced water, and nearly 12 million bbl of associated wastes in 1985. Current exploration and production activities are believed to be generating comparable quantities of these oil field wastes. Wakim estimates that 28% of drilling wastes, less than 2% of produced water, and 52% of associated wastes are disposed of in off-site commercial facilities. In recent years, interest in disposing of oil field wastes in solution-mined salt caverns has been growing. This report provides information on the availability of commercial disposal companies in oil-and gas-producing states, the treatment and disposal methods they employ, and the amounts they charge. It also compares cavern disposal costs with the costs of other forms of waste disposal.

  2. Structural Stability Monitoring of a Physical Model Test on an Underground Cavern Group during Deep Excavations Using FBG Sensors

    Directory of Open Access Journals (Sweden)

    Yong Li

    2015-08-01

    Full Text Available Fiber Bragg Grating (FBG sensors are comprehensively recognized as a structural stability monitoring device for all kinds of geo-materials by either embedding into or bonding onto the structural entities. The physical model in geotechnical engineering, which could accurately simulate the construction processes and the effects on the stability of underground caverns on the basis of satisfying the similarity principles, is an actual physical entity. Using a physical model test of underground caverns in Shuangjiangkou Hydropower Station, FBG sensors were used to determine how to model the small displacements of some key monitoring points in the large-scale physical model during excavation. In the process of building the test specimen, it is most successful to embed FBG sensors in the physical model through making an opening and adding some quick-set silicon. The experimental results show that the FBG sensor has higher measuring accuracy than other conventional sensors like electrical resistance strain gages and extensometers. The experimental results are also in good agreement with the numerical simulation results. In conclusion, FBG sensors could effectively measure small displacements of monitoring points in the whole process of the physical model test. The experimental results reveal the deformation and failure characteristics of the surrounding rock mass and make some guidance for the in situ engineering construction.

  3. Congenital tri-cavernous hemangiomas of the right buccal region, right accessory parotid gland, and masseter muscle region.

    Science.gov (United States)

    Yang, Tao; Gu, Yongchun; Zhang, Li; Hua, Zequan

    2014-03-01

    We report a rare case of congenital tri-cavernous hemangiomas of the right buccal region, right accessory parotid gland, and masseter muscle region in an adult. The patient, a 25-year-old woman, complained of 3 masses in her right midcheek. Ultrasonographic and computed tomographic findings showed an irregular-shaped mass (multiple calcifications) with a well-defined margin in the masseter muscle region, an ellipse-shaped mass (multiple calcifications) with a well-defined margin in the right buccal region, and a comma-shaped mass (no calcifications) with a well-defined margin separate from the parotid gland in the right accessory parotid gland region. These iconographic findings suggested that the masses were all hemangiomas separately originating from the parotid gland, accessory parotid gland, and masseter muscle. The masses were completely removed through a standard parotid incision without postoperative facial palsy, skin deformity, and difficulty in secreting saliva. Findings from histologic examination of the tumor revealed multiple, thin-walled, and dilated blood vessels, confirming the diagnosis of cavernous hemangiomas. Ultrasonographic and computed tomographic findings were extremely useful in diagnosing the mass/masses as hemangioma before surgery, clarifying relationships between the mass and adjacent structures, and determining the surgical approach to the mass/masses.

  4. Sodium alginate microsphere combined with pingyangmycin lipiodol emulsion for clinical treatment of cavernous hemangioma of the liver

    International Nuclear Information System (INIS)

    Yu Miao; Zhang Jinshan; Deng Liping

    2010-01-01

    Objective: To further reduce the adverse reactions of vascular embolization therapy for cavernous hemangioma of the liver (CHL) in order to find better embolizing agents. Methods: Sixty CHL patients were randomly and evenly divided into three groups: embolization therapy with sodium alginate microsphere(SAM) + pingyangmycin lipiodol emulsion (PLE) (group SAM + PLE), PLE (group PLE) and SAM (group SAM). The routine postoperative symptomatic treatments were conducted, including odynolysis, liver-protection and antiinflammatory therapy. The liver function and the intraoperative or postoperative discomfort symptoms before and 7 days after operation, and the changes in tumors were examined with CT scan. Clinical symptoms 3 months after operation were respectively compared. Results: The greatest impact on liver function was seen in group PLE among the three groups. The maximum intraoperative or postoperative discomfort symptoms were seen in group SAM, but the therapeutic effectiveness of the three groups had no significant difference. Conclusion: SAM + PLE is a safe and effective embolizing agent, being user-friendly, minor in the effect on liver function and light in the intraoperative and postoperative reaction. It is recommended that SAM + PLE be widely used for cavernous hemangioma of the liver. (authors)

  5. Single-Session Hematoma Removal and Transcranial Coil Embolization for a Cavernous Sinus Dural Arteriovenous Fistula: A Technical Case Report.

    Science.gov (United States)

    Akamatsu, Yosuke; Sato, Kenichi; Endo, Hidenori; Matsumoto, Yasushi; Tominaga, Teiji

    2017-08-01

    Patients with cavernous sinus dural arteriovenous fistulas (CS dAVFs) with cortical venous varix are indicated for aggressive treatment because of the associated risk for intracranial hemorrhage. We present a case of surgical transvenous embolization in an 84-year-old woman with CS dAVF who presented with massive intracerebral hematoma. Cerebral angiograms revealed the dural AVF drained only into the superficial middle cerebral vein. Because an emergent mass reduction and prevention of rebleeding were necessary, single-session hematoma removal and transcranial embolization of a CS dAVF were performed in the neurosurgical operating room, using a mobile C-arm fluoroscopy. After the right frontotemporal craniotomy, intracerebral hematoma was removed and coil packing of the affected cavernous sinus was successfully performed via the dilated superficial middle cerebral vein. The transcortical vein approach enables occlusion of CS dAVF with isolated cortical venous drainage and may be a valuable alternative approach for some cases needed emergency craniotomy. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Magnetic resonance diffusion tensor imaging and tractography of intracranial cavernous malformations: preliminary observations and characterization of the hemosiderin rim.

    Science.gov (United States)

    Cauley, Keith A; Andrews, Trevor; Gonyea, Jay V; Filippi, Christopher G

    2010-04-01

    Cavernous malformations (CMs) can cause symptoms that appear out of proportion to the lesion size, leading one to hypothesize that they may have an effect on adjacent white matter that is not fully explained by local mass effect. The goal of this study was to investigate the diffusion tensor (DT) properties of CMs, the hemosiderin rim, and normal-appearing adjacent white matter. Eighteen cavernous malformations were characterized using standard MR imaging sequences as well as 6-direction DT imaging with single-shot echo planar-gradient echo imaging at 3 tesla. Diffusion tensor imaging demonstrated that CMs have a characteristic signature on DT imaging, with low fractional anisotropy (FA) and high mean diffusivity centrally within the lesion. The hemosiderin rim had a high FA value relative to the central lesion or adjacent white matter. Tractography revealed that tracts neatly deviate around CMs. Tracts were typically seen to pass through the hemosiderin rim. The hemosiderin rim of CMs was intimately associated with white matter tracts that were deviated by the central lesion. These findings are consistent with histopathological reports that the hemosiderin rim is composed of blood breakdown products deposited in viable white matter.

  7. Feasibility of using intravascular ultrasonography for assessment of giant cavernous aneurysm after endovascular treatment: a technical report.

    Science.gov (United States)

    Majidi, Shahram; Grigoryan, Mikayel; Tekle, Wondwossen G; Watanabe, Masaki; Qureshi, Adnan I

    2012-06-01

    Intravascular ultrasonography (IVUS) has been shown as a valuable adjunct imaging tool during endovascular procedures but its value in detection of any recurrence during follow up after endovascular coil embolization of large and giant intracranial aneurysms is not reported. A 41 years old man who had been treated using stent assisted coil embolization for cavernous segment aneurysm of the left internal carotid artery underwent 60 month angiographic follow up. Concurrently, IVUS catheter was advanced under fluoroscopic guidance inside the cavernous portion of the left internal carotid artery. Then IVUS images were used to visualize the stent, coil loops, and aneurysm neck. The angiographic images were limited because of superimposition of the aneurysm on the parent vessel in all projections. IVUS images demonstrated that the stent was patent along its whole length and there was no sign of stent deformity or in-stent thrombosis. Loops of the coil were visualized as hyperechoic signals inside the aneurysm and there was no sign of herniated loops of coil inside the stent. In this case report, we observed that adjunct use of IVUS can provide valuable information not ascertained by angiography during follow up assessment of coil embolized aneurysm.

  8. Cooperative work program between ERDA/OWI and the Swedish State Power Board on waste storage in mined caverns

    International Nuclear Information System (INIS)

    Witherspoon, P.A.

    1977-01-01

    Recent conferences between members of OWI and LBL, and members of the Swedish State Power Board have revealed that an abandoned iron ore mine in Stripa, Sweden, can be used in a very profitable manner for a cooperative work program on the problem of radioactive waste storage in mined caverns. The main thrust of this cooperative work program will be to determine the feasibility of using a mined cavern in hard rock as a permanent repository for high level radioactive materials. The ERDA/OWI program is directed along different lines that complement the Swedish program. Seven tasks are involved as follows: Task 1 will investigate over a two-year period the temperature effects in the granite rock mass at Stripa using a full scale electric heater that simulates the energy output of radioactive waste canisters. Task 2 will determine the long term effect of waste heat in a fractured rock mass. Task 3 will assess the fracture hydrology in the Stripa mine. Task 4 will involve geophysical measurements to determine the locations of the fracture system in the granite rock mass. Task 5 is a laboratory investigation on the measurement of rock properties that are urgently needed in the overall problem of evaluating repository sites in the U.S. Task 6 will involve a method of measuring the gross seepage rate in the low permeability granitic rocks at Stripa. Task 7 will determine the virgin state of stress in the fractured granite rock mass at Stripa

  9. Numerical simulation for the coupled thermo-mechanical performance of a lined rock cavern for underground compressed air energy storage

    Science.gov (United States)

    Zhou, Shu-Wei; Xia, Cai-Chu; Zhao, Hai-Bin; Mei, Song-Hua; Zhou, Yu

    2017-12-01

    Compressed air energy storage (CAES) is a technology that uses compressed air to store surplus electricity generated from low power consumption time for use at peak times. This paper presents a thermo-mechanical modeling for the thermodynamic and mechanical responses of a lined rock cavern used for CAES. The simulation was accomplished in COMSOL Multiphysics and comparisons of the numerical simulation and some analytical solutions validated the thermo-mechanical modeling. Air pressure and temperatures in the sealing layer and concrete lining exhibited a similar trend of ‘up-down-down-up’ in one cycle. Significant temperature fluctuation occurred only in the concrete lining and sealing layer, and no strong fluctuation was observed in the host rock. In the case of steel sealing, principal stresses in the sealing layer were larger than those in the concrete and host rock. The maximum compressive stresses of the three layers and the displacement on the cavern surface increased with the increase of cycle number. However, the maximum tensile stresses exhibited the opposite trend. Polymer sealing achieved a relatively larger air temperature and pressure compared with steel and air-tight concrete sealing. For concrete layer thicknesses of 0 and 0.1 m and an initial air pressure of 4.5 MPa, the maximum rock temperature could reach 135 °C and 123 °C respectively in a 30 day simulation.

  10. Numerical Simulation of Blast Vibration and Crack Forming Effect of Rock-Anchored Beam Excavation in Deep Underground Caverns

    Directory of Open Access Journals (Sweden)

    XinPing Li

    2017-01-01

    Full Text Available Aiming at surrounding rock damage induced by dynamic disturbance from blasting excavation of rock-anchored beam in rock mass at moderate or far distance in underground cavern, numerical model of different linear charging density and crustal stress in underground cavern is established by adopting dynamic finite element software based on borehole layout, charging, and rock parameter of the actual situation of a certain hydropower station. Through comparison in vibration velocity, contour surface of rock mass excavation, and the crushing extent of excavated rock mass between calculation result and field monitoring, optimum linear charging density of blast hole is determined. Studies are also conducted on rock mass vibration in moderate or far distance to blasting source, the damage of surrounding rock in near-field to blasting source, and crushing degree of excavated rock mass under various in situ stress conditions. Results indicate that, within certain range of in situ stress, the blasting vibration is independent of in situ stress, while when in situ stress is increasing above certain value, the blasting vibration velocity will be increasing and the damage of surrounding rock and the crushing degree of excavated rock mass will be decreasing.

  11. Reliable? The Value of Early Postoperative Magnetic Resonance Imaging after Cerebral Cavernous Malformation Surgery.

    Science.gov (United States)

    Chen, Bixia; Göricke, Sophia; Wrede, Karsten; Jabbarli, Ramazan; Wälchli, Thomas; Jägersberg, Max; Sure, Ulrich; Dammann, Philipp

    2017-07-01

    Cerebral cavernous malformations (CCM) can cause intracerebral hemorrhage. The lesions themselves are frequently associated with perifocal hemosiderin deposits caused by repetitive microhemorrhages. Main indications for a surgical treatment are recurrent symptomatic hemorrhages or cavernoma-related epilepsy. After surgical resection, follow-up magnetic resonance imaging (MRI) is usually performed to confirm 1) the complete resection of the CCM and, especially in cases of cavernoma-related epilepsy, 2) the complete resection of the hemosiderin deposits. This prospective study evaluates the value of early postoperative MRI (within 72 hours) regarding the detection of CCM or hemosiderin remnants compared with a standard 3-6 months postoperative MRI control in 61 CCM cases. Sensitivity of early postoperative MRI for CCM remnant detection was 66.67% (95% confidence interval [CI], 9.43%-99.16%), specificity was 76.74% (95% CI, 61.37%-88.24%), positive predictive value was 16.67% (95% CI, 2.09%-48.41%), and negative predictive value was 97.06% (95% CI, 84.67%-99.93%). Because of the high number of patients who could not be evaluated because of imaging artifacts, sensitivity and specificity analysis was not performed for early postoperative MRI using T2*/susceptibility-weighted imaging to assess hemosiderin remnants. Sensitivity of early postoperative MRI for hemosiderin remnant detection using T2-weighted sequences was 85.71% (95% CI, 63.66%-96.95%), specificity was 66.67% (95% CI, 44.68%-84.37%), positive predictive value was 69.23% (95% CI, 55.45%-80.27%), and negative predictive value was 84.21% (95% CI, 64.31%-94.04%). Our data suggest that early postoperative MRI after CCM surgery is often hampered by imaging artifacts creating false-positive results and therefore ineligible for a resection control. However, reliability of a negative result on early postoperative T2-weighted MRI is relatively high regarding both CCM and hemosiderin remnants. Copyright © 2017

  12. Temporal lobe epilepsy and cavernous malformations: surgical strategies and long-term outcomes.

    Science.gov (United States)

    Vale, Fernando L; Vivas, Andrew C; Manwaring, Jotham; Schoenberg, Mike R; Benbadis, Selim R

    2015-11-01

    Cerebral cavernous malformations (CCM) of the temporal lobe often present with seizures. Surgical resection of these lesions can offer durable seizure control. There is, however, no universally accepted methodology for assessing and surgically treating these patients. We propose an algorithm to maximize positive surgical outcomes (seizure control) while minimizing post-surgical neurological deficit. A retrospective review of 34 patients who underwent epilepsy surgery for radiographically proven temporal lobe CCM was conducted. Patients underwent a relatively standard work-up for seizure localization. In patients with mesial temporal lobe epilepsy (MTLE), a complete resection of the epileptogenic zone was performed including amygdalo-hippocampectomy in addition to a lesionectomy if not contraindicated by pre-operative work-up. Patients with neocortical epilepsy underwent intraoperative electrocorticography (ECoG)-guided lesionectomy. Seizure-free rate for mesial and neocortical (anterior, lateral, and basal) location was 90 vs. 83 %, respectively. Complete resection of the lesion, irrespective of location, was statistically significant for seizure control (p = 0.018). There was no difference in seizure control based on disease duration or location (p > 0.05). Patients with mesial temporal CCM who presented with MTLE were presumed to also have mesial temporal sclerosis (MTS), or dual pathology. These patients underwent routine resection of the mesial structures. Interestingly, patients who had MTLE and basal (neocortical) lesions who underwent a mesial resection for suspected MTS were found not to have dual pathology. Patients with temporal lobe CCM should be offered resection for durable seizure control, prevention of secondary epileptogenic foci, and elimination of hemorrhage risk. The preoperative work-up should follow a team approach. Surgical intervention should include complete lesionectomy in all cases. Intra or extra-operative ECoG for neocortical

  13. The ATLAS installation team, led by Tommi Nyman, after having positioned the Barrel Calorimeter in its final location in the ATLAS experimental cavern UX15

    CERN Multimedia

    2005-01-01

    On Friday 4th November, the ATLAS Barrel Calorimeter was moved from its assembly point at the side of the ATLAS cavern to the centre of the toroidal magnet system. The detector was finally aligned, to the precision of within a millimetre, on Wednesday 9th November.

  14. Direct percutaneous transorbital puncture under fluoroscopic guidance with a 3D skull reconstruction overlay for embolisation of intraorbital and cavernous sinus dural arteriovenous fistulas.

    Science.gov (United States)

    Lv, Ming; Jiang, Chuhan; Liu, Dong; Ning, Zhiguang; Yang, Jun; Wu, Zhongxue

    2015-06-01

    To describe the direct percutaneous transorbital puncture technique for embolisation of the selected intraorbital and cavernous sinus dural arteriovenous fistula, which failed to be treated by conventional endovascular techniques. One case of intraorbital and five cases of cavernous sinus dural arteriovenous fistula were embolised through direct percutaneous transorbital puncture in 2012, and the clinical data were reviewed. Under fluoroscopic guidance with a three-dimensional (3D) skull reconstruction overlay, the cavernous sinus or ophthalmic vein was punctured via the superior orbital fissure. Then a microcatheter was inserted via the needle, and Onyx was injected to embolise the fistula with or without a combination of coils. Complete obliteration of the fistula was achieved in all six patients. After operation all the patients experienced transient swelling of the punctured orbit persisting for three to five days. No other complications occurred. Follow-up of six patients at three to six months showed resolution of their initial neuro-ophthalmological symptoms in five and left visual loss in one did not recover. Six months follow-up angiogram showed no recurrence of these fistulas. Direct percutaneous transorbital puncture provides an option for the intraorbital and cavernous sinus dural arteriovenous fistulas, particularly when the conventional transvenous routes are inaccessible. Overlay of the 3D skull reconstruction can facilitate the precise puncture of the superior orbital fissure. © The Author(s) 2015.

  15. Trans-zygomatic middle cranial fossa approach to access lesions around the cavernous sinus and anterior parahippocampus: a minimally invasive skull base approach.

    Science.gov (United States)

    Melamed, Itay; Tubbs, R Shane; Payner, Troy D; Cohen-Gadol, Aaron A

    2009-08-01

    Exposure of the cavernous sinus or anterior parahippocampus often involves a wide exposure of the temporal lobe and mobilization of the temporalis muscle associated with temporal lobe retraction. The authors present a cadaveric study to illustrate the feasibility, advantages and landmarks necessary to perform a trans-zygomatic middle fossa approach to lesions around the cavernous sinus and anterior parahippocampus. The authors performed bilateral trans-zygomatic middle fossae exposures to reach the cavernous sinus and parahippocampus in five cadavers (10 sides). We assessed the morbidity associated with this procedure and compared the indications, advantages, and disadvantages of this method versus more extensive skull base approaches. A vertical linear incision along the middle portion of the zygomatic arch was extended one finger breadth inferior to the inferior edge of the zygomatic arch. Careful dissection inferior to the arch allowed preservation of facial nerve branches. A zygomatic osteotomy was followed via a linear incision through the temporalis muscle and exposure of the middle cranial fossa floor. A craniotomy along the inferolateral temporal bone and middle fossa floor allowed extradural dissection along the middle fossa floor and exposure of the cavernous sinus including all three divisions of the trigeminal nerve. Intradural inspection demonstrated adequate exposure of the parahippocampus. Exposure of the latter required minimal or no retraction of the temporal lobe. The trans-zygomatic middle fossa approach is a simplified skull base exposure using a linear incision, which may avoid the invasivity of more extensive skull base approaches while providing an adequate corridor for resection of cavernous sinus and parahippocampus lesions. The advantages of this approach include its efficiency, ease, minimalism, preservation of the temporalis muscle, and minimal retraction of the temporal lobe.

  16. The utility of preoperative diffusion tensor imaging in the surgical management of brainstem cavernous malformations.

    Science.gov (United States)

    Flores, Bruno C; Whittemore, Anthony R; Samson, Duke S; Barnett, Samuel L

    2015-03-01

    Resection of brainstem cavernous malformations (BSCMs) may reduce the risk of stepwise neurological deterioration secondary to hemorrhage, but the morbidity of surgery remains high. Diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) are neuroimaging techniques that may assist in the complex surgical planning necessary for these lesions. The authors evaluate the utility of preoperative DTI and DTT in the surgical management of BSCMs and their correlation with functional outcome. A retrospective review was conducted to identify patients who underwent resection of a BSCM between 2007 and 2012. All patients had preoperative DTI/DTT studies and a minimum of 6 months of clinical and radiographic follow-up. Five major fiber tracts were evaluated preoperatively using the DTI/DTT protocol: 1) corticospinal tract, 2) medial lemniscus and medial longitudinal fasciculus, 3) inferior cerebellar peduncle, 4) middle cerebellar peduncle, and 5) superior cerebellar peduncle. Scores were applied according to the degree of distortion seen, and the sum of scores was used for analysis. Functional outcomes were measured at hospital admission, discharge, and last clinic visit using modified Rankin Scale (mRS) scores. Eleven patients who underwent resection of a BSCM and preoperative DTI were identified. The mean age at presentation was 49 years, with a male-to-female ratio of 1.75:1. Cranial nerve deficit was the most common presenting symptom (81.8%), followed by cerebellar signs or gait/balance difficulties (54.5%) and hemibody anesthesia (27.2%). The majority of the lesions were located within the pons (54.5%). The mean diameter and estimated volume of lesions were 1.21 cm and 1.93 cm(3), respectively. Using DTI and DTT, 9 patients (82%) were found to have involvement of 2 or more major fiber tracts; the corticospinal tract and medial lemniscus/medial longitudinal fasciculus were the most commonly affected. In 2 patients with BSCMs without pial presentation, DTI

  17. On the use of hydrate inhibitors for operating natural gas caverns; Zum Einsatz von Hydratinhibitoren beim Betrieb von Erdgasspeichern

    Energy Technology Data Exchange (ETDEWEB)

    Kleinitz, W.; Lissanon, S.J.; Luehn, H.G. [Preussag Energie GmbH, Lingen/Ems (Germany)

    1997-12-31

    One way to prevent gas hydrates in natural gas caverns is to use thermodynamic or kinetic inhibitors in a defined temperature / pressure range. The present contribution describes the temperature conditions prevailing in the tubing string. It also discusses bacterial processes around wells arising in association with methanol digesting bacteria, diethylene glycol digesting bacteria, and kinetic inhibitors. Further topics include inhibitor dosage and absorption drying. (MSK) [Deutsch] Zur Vermeidung von Gashydraten im Erdgasspeicherbereich werden thermodynamische oder kinetische Inhibitoren in einem definierten Temperatur/Druckbereich eingesetzt. Im Folgenden werden die Temperaturbedingungen im Steigrohrsystem erlaeutert. Ebenso werden die bakteriellen Vorgaenge im Bohrlochsbereich in folgenden Einzelheiten: Methanol-verwertenden Bakterien, Diethylenglykol-verwertende Bakterien sowie kinetische Inhibitoren diskutiert. Weitere Themenpunkte sind die Inhibitordosierung und die Adsorptionstrocknung.

  18. A variant epidemic methicillin resistant Staphylococcus aureus-15 cavernous sinus thrombosis and meningitis: A rare occurrence with unusual presentation

    Directory of Open Access Journals (Sweden)

    Veena Kumari H

    2010-01-01

    Full Text Available Septic cavernous sinus thrombosis (CST is an uncommon clinical syndrome. Although Staphylococcus aureus (S aureus is the most common bacterial pathogen causing CST, it is infrequent as a cause of meningitis. We report the first case of CST and meningitis from Bengaluru, Karnataka, caused by community-acquired epidemic methicillin resistant Staphylococcus aureus-15 (EMRSA-15, in a previously healthy individual without known risk factors; the patient recovered following treatment with vancomycin. The isolate was genotyped as belonging to staphylococcal cassette chromosome mec type IV and sequence type 22 and carried the panton-valentine leucocidin gene. It is the first Indian EMRSA-15 disease isolate from a case of meningitis. EMRSA-15 has been a major problem in hospitals in UK and it is a cause for great concern in Indian hospitals too.

  19. Cavernous hemangioma of the bladder in a child of 6 years and 11 months

    Directory of Open Access Journals (Sweden)

    N. I. Zryachkin

    2017-01-01

    Full Text Available We analyze a clinical case of the patient at the age of 6 years and 11 months with a cavernous hemangioma of the bladder. The disease manifested with isolated macrohaematuria. During the diagnostic assessment by 3D-ultrasound examination of the urinary tract with tight bladder filling, a mass with tuberous shape and echonegative areas inside was visualized on the left bladder wall close to its anterior surface, while external bladder contours were unchanged. Color Doppler mapping showed some vessels in the projection of the mass sprouting from the muscular layer of the bladder. The neoplasm was confirmed by abdominopelvic magnetic resonance imaging (with and without contrast enhancement and by cystoscopy. Taking into account familial cancer history of the patient (oncological disorders in the maternal and paternal lines and high degree of vascularization of the mass, a malignancy (rhabdomyosarcoma was deemed highly probable. At 2 months after the disease manifestation, transurethral endoscopic surgery was performed with coagulation and a resection of an exophytic mass of 1 cm in diameter, with a wide base, irregular tuberous shape, brown colored, with a cystic component. The mucous layer on the lateral bladder wall was abnormal with some hemorrhages. Histological examination of the tissue sample showed a  cavernous hemangioma, that was the final diagnosis in this patient. During subsequent 2-year follow up, there was no recurrence of the disease. The described case is of clinical interest because bladder hemangiomas are rare in children; therefore, this disease should be on the list for differential diagnosis in children with macrohaematuria.

  20. A study on the methodology of penile cavernous dynamic imaging for evaluating vasculogenic impotence using 99mTc

    International Nuclear Information System (INIS)

    Cao Jianmin; Shen Ming; Huang Weili

    1996-01-01

    To develop a new quantitative diagnosis method for vasculogenic impotence, the penile cavernous hemodynamic changes of 6 normal volunteers and 24 impotent were studied using 99m Tc-RBC 370 MBq and 99m Tc-PHY 37 MBq. The arterial and venous penile images were evaluated with intravenous and intracavernous administration of 99m Tc and also monitored both before and after intracavernous papaverine injection. The recirculation of 99m Tc-PHY were calculated by measuring the counts of liver tissue and venous blood. The penogram index of arterial system (PIA) of 6 volunteers was 0.90 +- 0.38, 1/2 peak time was 1.84 +- 0.50 min, and the penogram index of venous system (PIV) was -0.21 +- 0.06. PIA>0.60 and PIV>-0.45 were accepted as normal. According to this normal value 24 impotent patients were classified into 4 groups: 4 with psychogenic impotence (PIA 0.72 +- 0.16, PIV -0.32 +- 0.08); 9 with venogenic impotence (PIA 0.86 +- 0.25, PIV -0.75 +-0.13); 5 with the arteriogenic impotence (PIA 0.28 +- 0.09, PIV -0.29 +-0.21); 6 with both arteriogenic and venogenic impotence (PIA 0.28 +- 0.17, PIV -0.75 +- 0.12). The cavernous of 99m Tc-PHY value due to recirculation is very low, and is less than 0.01. The radioisotope erection penogram is a safe, noninvasive and valuable screening test in the identification of vasculogenic impotence, and is effective in differentiating arteriogenic and venogenic impotence

  1. 09 September 2013 - Japanese Members of Internal Affairs and Communications Committee House of Representatives visiting the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton. T. Kondo and K. Yoshida present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    09 September 2013 - Japanese Members of Internal Affairs and Communications Committee House of Representatives visiting the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton. T. Kondo and K. Yoshida present.

  2. 12 April 2013 - The British Royal Academy of Engineering visiting the LHC superconducting magnet test hall with R. Veness and the ATLAS experimental cavern with Collaboration Spokesperson D. Charlton.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    12 April 2013 - The British Royal Academy of Engineering visiting the LHC superconducting magnet test hall with R. Veness and the ATLAS experimental cavern with Collaboration Spokesperson D. Charlton.

  3. 19 September 2012 - Indonesian Members of Parliament visiting the CMS control room and experimental cavern at Point 5 with Former Deputy Spokesperson A. De Roeck and International Relations Adviser E. Tsesmelis.

    CERN Multimedia

    Jean-Claude Gadmer

    2012-01-01

    19 September 2012 - Indonesian Members of Parliament visiting the CMS control room and experimental cavern at Point 5 with Former Deputy Spokesperson A. De Roeck and International Relations Adviser E. Tsesmelis.

  4. 29 May 2013 - Rector Politecnico di Torino M. Gilli in the ATLAS experimental cavern with L. Pontecorvo (ATLAS Collaboration) and in the LHC tunnel at Point 1 with Engineering Department Head R. Saban.

    CERN Multimedia

    VMO

    2013-01-01

    29 May 2013 - Rector Politecnico di Torino M. Gilli in the ATLAS experimental cavern with L. Pontecorvo (ATLAS Collaboration) and in the LHC tunnel at Point 1 with Engineering Department Head R. Saban.

  5. Dr Mauro Dell’Ambrogio, State Secretary for Education and Research of the Swiss Confederation visit the ATLAS Cavern and the LHC Machine with with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    Dr Mauro Dell’Ambrogio, State Secretary for Education and Research of the Swiss Confederation visit the ATLAS Cavern and the LHC Machine with with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

  6. 21 October 2008 - LHC Inauguration - Deputy Minister for Environment, Physical Planning and Public Works T. Xanthopulos welcomed by CERN Director-General R. Aymar, visiting the ATLAS cavern and LHC tunnel and signing the electronic guest book with E. Tsesmelis.

    CERN Document Server

    CERN Photo Service

    2008-01-01

    21 October 2008 - LHC Inauguration - Deputy Minister for Environment, Physical Planning and Public Works T. Xanthopulos welcomed by CERN Director-General R. Aymar, visiting the ATLAS cavern and LHC tunnel and signing the electronic guest book with E. Tsesmelis.

  7. His Excellency Mr Valery Loshchinin Extraordinary and plenipotentiary Ambassador Permanent Representative of the Russian Federation to the United Nations Office in Geneva visit the ATLAS experiment in the cavern at Point 1 introducted by Prof. Peter Jenni.

    CERN Document Server

    Maximilien Brice

    2007-01-01

    His Excellency Mr Valery Loshchinin Extraordinary and plenipotentiary Ambassador Permanent Representative of the Russian Federation to the United Nations Office in Geneva visit the ATLAS experiment in the cavern at Point 1 introducted by Prof. Peter Jenni.

  8. 18 MArch 2008 - Director, Basic and Generic Research Division, Research Promotion Bureau, Japanese Ministry of Education, Culture, Sports, Science and Technology Prof.Ohtake visiting ATLAS cavern with Spokesperson P. Jenni.

    CERN Document Server

    Maximilien Brice

    2008-01-01

    18 MArch 2008 - Director, Basic and Generic Research Division, Research Promotion Bureau, Japanese Ministry of Education, Culture, Sports, Science and Technology Prof.Ohtake visiting ATLAS cavern with Spokesperson P. Jenni.

  9. 17 September 2013 - Polish Members of Parliament visiting the Tunnel at Point 2 with Senior Engineer, Technology Department A. Siemko and visiting the ALICE cavern with ALICE Collaboration, B. Erazmus

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    17 September 2013 - Polish Members of Parliament visiting the Tunnel at Point 2 with Senior Engineer, Technology Department A. Siemko and visiting the ALICE cavern with ALICE Collaboration, B. Erazmus

  10. 10 September 2013 - Italian Minister for Economic Development F. Zanonato visiting the ATLAS cavern with Collaboration Spokesperson D. Charlton and Italian scientists F. Gianotti and A. Di Ciaccio; signing the guest book with CERN Director-General R. Heuer and Director for Research and Scientific Computing S. Bertolucci; in the LHC tunnel with S. Bertolucci, Technology Deputy Department Head L. Rossi and Engineering Department Head R. Saban; visiting CMS cavern with Scientists G. Rolandi and P. Checchia.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    10 September 2013 - Italian Minister for Economic Development F. Zanonato visiting the ATLAS cavern with Collaboration Spokesperson D. Charlton and Italian scientists F. Gianotti and A. Di Ciaccio; signing the guest book with CERN Director-General R. Heuer and Director for Research and Scientific Computing S. Bertolucci; in the LHC tunnel with S. Bertolucci, Technology Deputy Department Head L. Rossi and Engineering Department Head R. Saban; visiting CMS cavern with Scientists G. Rolandi and P. Checchia.

  11. Proposal to negotiate amendments to an existing contract for the supply of steel structures for the LHC shafts, tunnels, caverns and experimental areas

    CERN Document Server

    2005-01-01

    This document concerns the proposal to negotiate amendments to an existing contract for the supply of additional steel structures for the LHC shafts, tunnels, caverns and experimental areas. For the reasons explained in this document, the Finance Committee is invited to approve amendments to the existing contract with the firm INIZIATIVE INDUSTRIALI (IT) for the supply of additional steel structures for the LHC shafts, tunnels, caverns and experimental areas for an amount of 500 000 euros (775 000 Swiss francs), subject to revision for inflation, bringing the total to 6 525 745 euros (10 114 905 Swiss francs), subject to revision for inflation. The amounts in Swiss francs have been calculated using the present rate of exchange.

  12. Successful Treatment of Dental Infection-Induced Chronic Cavernous Sinus Thrombophlebitis With Antibiotics and Low-Molecular-Weight Heparin: Two Case Reports.

    Science.gov (United States)

    Li, Yuan; Zheng, Bo; Chen, Kangning; Gui, Li

    2015-08-01

    Two patients developed cavernous sinus thrombophlebitis from a tooth infection. A 36-year-old man experienced a severe headache with bilateral third and sixth cranial nerve palsies after extraction of his left upper third molar. Another 53-year-old diabetic man developed fever, headache, and bilateral complete ophthalmoplegia after a tooth infection. The brain magnetic resonance imaging scans of both patients showed bilateral cavernous sinus partial thrombosis. Broad-spectrum antibiotics plus low-molecular-weight heparin successfully resolved all symptoms. Both patients recovered fully without any recurrence at the 3-month follow-up visit. Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  13. Endovascular treatment of a cavernous sinus dural arteriovenous fistula by transvenous embolisation through the superior ophthalmic vein via cannulation of a frontal vein

    International Nuclear Information System (INIS)

    Venturi, C.; Bracco, S.; Cerase, A.; Gennari, P.; Lore, F.; Polito, E.; Casasco, A.E.

    2003-01-01

    We describe a new approach for transvenous embolisation of cavernous sinus dural arteriovenous fistulae through the superior ophthalmic vein (SOV), i.e., via percutaneous cannulation of a frontal vein. Modern neurointerventional angiographic materials make it possible to reach the SOV in this way without puncturing it in the orbit or a surgical exposure. Orbital phlebography should still be in the repertoire of interventional neuroradiology units in large centres. (orig.)

  14. Intravenous Infusion of Bone Marrow-Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in Rats.

    Science.gov (United States)

    Matsuda, Yohei; Sasaki, Masanori; Kataoka-Sasaki, Yuko; Takayanagi, Akio; Kobayashi, Ko; Oka, Shinichi; Nakazaki, Masahito; Masumori, Naoya; Kocsis, Jeffery D; Honmou, Osamu

    2018-03-01

    Intravenous preload (delivered before cavernous nerve [CN] injury) of bone marrow-derived mesenchymal stem cells (MSCs) can prevent or decrease postoperative erectile dysfunction (J Sex Med 2015;12:1713-1721). In the present study, the potential therapeutic effects of intravenously administered MSCs on postoperative erectile dysfunction were evaluated in a rat model of CN injury. Male Sprague-Dawley rats were randomized into 2 groups after electric CN injury. Intravenous infusion of bone marrow-derived MSCs (1.0 × 10 6 cells in Dulbecco's modified Eagle's medium 1 mL) or vehicle (Dulbecco's modified Eagle's medium 1 mL) was performed 3 hours after electrocautery-induced CN injury. To assess erectile function, we measured intracavernous pressure at 4 weeks after MSC or vehicle infusion. Histologic examinations were performed to investigate neuronal innervation and inhibition of smooth muscle atrophy. Green fluorescent protein-positive bone marrow-derived MSCs were used for cell tracking. To investigate mRNA expression levels of neurotrophins in the major pelvic ganglia (MPGs), quantitative real-time polymerase chain reaction was performed. The decrease of intracavernous pressure corrected for arterial pressure and area under the curve of intracavernous pressure in the bone marrow-derived MSC group was significantly lower than that in the vehicle group at 4 weeks after infusion (P derived MSCs were detected in the MPGs and injured CNs using confocal microscopy, indicating homing of cells to the MPGs and injured CNs. Brain-derived neurotrophic factor and glial cell-derived neurotrophic factor expression levels in the MPGs were significantly higher in the MSC group than in the vehicle group (P derived MSCs after CN injury might have therapeutic efficacy in experimental erectile dysfunction. Matsuda Y, Sasaki M, Kataoka-Sasaki Y, et al. Intravenous Infusion of Bone Marrow-Derived Mesenchymal Stem Cells Reduces Erectile Dysfunction Following Cavernous Nerve Injury in

  15. Identification of mechanisms involved in the relaxation of rabbit cavernous smooth muscle by a new nitric oxide donor ruthenium compound

    Directory of Open Access Journals (Sweden)

    João Batista Gadelha de Cerqueira

    2012-10-01

    Full Text Available PURPOSE: The aim of this study was to evaluate the relaxation in vitro of cavernous smooth muscle induced by a new NO donor of the complex nitrosil-ruthenium, named trans-[Ru(NH34(caffeine(NO]C13 (Rut-Caf and sodium nitroprusside (SNP. MATERIALS AND METHODS: The tissues, immersed in isolated bath systems, were pre-contracted with phenilephrine (PE (1 µM and then concentration-response curves (10-12 - 10-4 M were obtained. To clarify the mechanism of action involved, it was added to the baths ODQ (10 µM, 30 µM, oxyhemoglobin (10 µM, L-cysteine (100 µM, hydroxicobalamine (100 µM, glibenclamide, iberotoxin and apamine. Tissue samples were frozen in liquid nitrogen to measure the amount of cGMP and cAMP produced. RESULTS: The substances provoked significant relaxation of the cavernous smooth muscle. Both Rut-Caf and SNP determined dose-dependent relaxation with similar potency (pEC50 and maximum effect (Emax. The substances showed activity through activation of the soluble guanylyl cyclase (sGC, because the relaxations were inhibited by ODQ. Oxyhemoglobin significantly diminished the relaxation effect of the substances. L-cysteine failed to modify the relaxations caused by the agents. Hydroxicobalamine significantly diminished the relaxation effect of Rut-Caf. Glibenclamide significantly increased the efficacy of Rut-Caf (pEC50 4.09 x 7.09. There were no alterations of potency or maximum effect of the substances with the addition of the other ion channel blockers. Rut-Caf induced production of significant amounts of cGMP and cAMP during the relaxation process. CONCLUSIONS: In conclusion, Rut-Caf causes relaxation of smooth muscle of corpus cavernosum by means of activation of sGC with intracellular production of cGMP and cAMP; and also by release of NO in the intracellular environment. Rut-Caf releases the NO free radical and it does not act directly on the potassium ion channels.

  16. Ultra-high-resolution C-arm flat-detector CT angiography evaluation reveals 3-fold higher association rate for sporadic intracranial cavernous malformations and developmental venous anomalies: a retrospective study in consecutive 58 patients with 60 cavernous malformations

    Energy Technology Data Exchange (ETDEWEB)

    Kocak, Burak [Aksaray State Hospital, Department of Radiology, Aksaray (Turkey); Kizilkilic, Osman; Kocer, Naci; Islak, Civan [Istanbul University, Department of Radiology, Cerrahpasa Medical Faculty, Istanbul (Turkey); Oz, Buge; Bakkaloglu, Dogu Vuralli [Istanbul University, Department of Pathology, Cerrahpasa Medical Faculty, Istanbul (Turkey); Isler, Cihan [Istanbul University, Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul (Turkey)

    2017-06-15

    The imaging and surgical literature has confusing association rates for the association between sporadic intracranial cavernous malformations (CMs) and developmental venous anomalies (DVAs). In this study, our purpose was to determine the association rate using ultra-high-resolution C-arm flat-detector CT angiography (FDCTA) and compare it with literature. Fifty-eight patients with 60 sporadic intracranial CMs that underwent an FDCTA study were included in our retrospective study. Re-evaluation of radiological data was performed based on the criteria defined by authors. Isotropic volumetric reconstructions with ultra-high resolution (voxel size of 102 μm{sup 3} for initial; 67 μm{sup 3} and 32 μm{sup 3} for further evaluation) were used for assessment. Sixteen patients underwent surgery for excision of their CMs. Fifty-one of all patients (87.9 %) were associated with a DVA. Undefined local venous structures (UD-LVSs) were observed in the remaining 7 patients (12.1 %). The strength of interobserver agreement was excellent [kappa(k) coefficient = 0.923]. Ultra-high-resolution FDCTA evaluation of CMs and DVAs reveals 3-fold higher association rate compared to the literature. FDCTA for patients with sporadic CMs could help identify the associated DVAs that remained undetected or unclear with other imaging modalities, which can be useful in decision-making processes, planning surgery, and during operation. (orig.)

  17. Numerical simulation for excavation and long-term behavior of large-scale cavern in soft rock

    International Nuclear Information System (INIS)

    Sawada, Masataka; Okada, Tetsuji

    2010-01-01

    Low-level radioactive waste is planned to be disposed at the depth of more than 50 m in Neogene tuff or tuffaceous sandstone. Generally there are few cracks in sedimentary soft rocks, thus it is considered to be easier to determine permeability of soft rocks than that of discontinuous rocks. On the other hand, sedimentary soft rocks show strong time-dependent behavior, and they are more sensitive to heat, groundwater, and their chemical effect. Numerical method for long-term behavior of underground facilities is necessary to their design and safety assessment. Numerical simulations for excavation of test cavern in disposal site are described in this report. Our creep model was applied to these simulations. Although it is able to reproduce the behavior of soft rock observed in laboratory creep test, simulation using parameters obtained from laboratory tests predicts much larger displacement than that of measurement. Simulation using parameters modified based on in-situ elastic wave measurement and back analysis reproduces measured displacements very well. Behavior of the surrounding rock mass during resaturation after setting of the waste and the engineered barrier system is also simulated. We have a plan to investigate chemical and mechanical interaction among soft rock, tunnel supports and engineered barriers, and to make their numerical models. (author)

  18. A true 3D physical model test study on the stability of an underground cavern group in Shuangjiangkou Hydropower Station

    Science.gov (United States)

    Zhu, Weishen; Zhang, Lei; Li, Yong; Zhang, Qianbing

    2010-03-01

    Taking the underground caverns of Shuangjiangkou (SJK) Hydropower Station as an engineering background, a largescale true 3D physical model test is performed to study the stability of the enclosing rock masses, including the analogous material, the steel structure frame, fabrications of rock bolts and cables, development of the measuring techniques, fabrication of the physical model, excavations and the overload test. The developed steel structure can simulate the complicated circumstances just like high in-situ stress and high overburden depth. It also can apply the true 3D loading on six surfaces of the physical model. Many combinational ball sliding blocks are installed between model surface and the structural wall to reduce the friction between the contact surfaces. During the model construction, precast blocks are used and monitoring holes are predefined before the analogous material is piled up. A unique grouting technique and prestressed cables are adopted in the model test. A digital photogrammetric technique, displacement sensing bars based on Fiber Bragg Gratings (FBG) technology, and mini extensometers are developed and adopted for measuring the deformation in the process of excavations. The overload tests are accomplished under the conditions of different overburden depths. The results of this research will make certain guiding significance to the practical engineering.

  19. The association between cerebral developmental venous anomaly and concomitant cavernous malformation: an observational study using magnetic resonance imaging.

    Science.gov (United States)

    Meng, Guolu; Bai, Chuanfeng; Yu, Tengfei; Wu, Zhen; Liu, Xing; Zhang, Junting; zhao, Jizong

    2014-03-15

    Some studies reported that cerebral developmental venous anomaly (DVA) is often concurrent with cavernous malformation (CM). But there is lack of statistical evidence and study of bulk cases. The factors associated with concurrency are still unknown. The purpose of this study was to determine the prevalence of concomitant DVA and CM using observational data on Chinese patients and analyze the factors associated with the concurrency. The records of all cranial magnetic resonance imaging (MRI) performed between January 2001 and December 2012 in Beijing Tiantan Hospital were reviewed retrospectively. The DVA and CM cases were selected according to imaging reports that met diagnostic criteria. Statistical analysis was performed using the Pearson chi-square statistic for binary variables and multivariable logistic regression analysis for predictors associated with the concurrent CM. We reviewed a total of 165,230 cranial MR images performed during the previous 12 year period, and identified 1,839 cases that met DVA radiographic criteria. There were 205 patients who presented concomitant CM among the 1,839 DVAs. The CM prevalence in DVA cases (11.1%) was significantly higher than that in the non-DVA cases (2.3%) (PDVA. There is a higher chance of concurrent CM with DVA when the DVA has three or more medullary veins in the same MRI scanning section, when the DVA is infratentorial, and when there are multiple DVAs. When diagnosing DVA cases, physicians should be alerted to the possibility of concurrent CM.

  20. The transport of nonindigenous microorganisms into caves by human visitation: a case study at Carlsbad Caverns National Park

    Science.gov (United States)

    Griffin, Dale W.; Gray, Michael A.; Lyles, Michael B.; Northup, Diana E.

    2014-01-01

    A series of atmospheric investigations was conducted in Carlsbad Cavern to determine if human visitation is a possible cause for the contamination of the cave system with non-indigenous microorganisms. In 2004, site-specific culture-based data demonstrated that Staphylococcus spp. colony-forming units (CFUs) were the most prevalent members of the atmospheric community along the paved visitor trail (avg. 18.8% of CFU), while Knoellia spp. CFUs dominated off-trail locations (40.1% of CFU). Fungal culture data revealed that Penicillium and Aspergillus were prevalent in the Lunch Room where food is stored, sold, and consumed. Ubiquitous genera such as Cladosporium and Alternaria were prevalent near the Natural Entrance of the cave, and the general trend was a decrease in fungal CFUs with progression into the cave system, except for the area near the Lunch Room. Management practices such as prohibition of crumb-generating types of foods could be considered to protect cave health. In 2009, nonculture-based analyses demonstrated that Enterobacteriaceae were the dominant microbiota at sites along the descent trail and within the Lunch Room. Dominance of Enterobacteriaceae has not been previously demonstrated in caves. Either they are naturally occurring indigenous members, or their presence is a marker of anthropogenic contamination.

  1. Methodology to assess water presence on speleothems during periods of low precipitation, with implications for recharge sources - Kartchner Caverns, Arizona

    Science.gov (United States)

    Blasch, Kyle W.

    2011-01-01

    Beginning in January 2005, recharge processes and the presence of water on speleothems were monitored in Kartchner Caverns during a 44-month period when annual rainfall rates were 6 to 18 percent below the long-term mean. Electrical-resistance sensors designed to detect the presence of water were used to identify ephemeral streamflow in the channels overlying the cave as well as the movement of water within the cave system. Direct infiltration of precipitation through overhead rocks provided consistent inflow to the cave, but precipitation rates and subsequent infiltration rates were reduced during the comparatively dry years. Ephemeral stream-channel recharge through autogenic and allogenic processes, the predominant recharge mechanism during wetter periods, was limited to two low-volume events. From visual observations, it appeared that recharge from channel infiltration was equal to or less than recharge from overhead infiltration. Electrical-resistance sensors were able to detect thin films of water on speleothems, including stalactites, ribbons, and stalagmites. These films of water were directly attributed to overhead infiltration of precipitation. Periods of low precipitation resulted in decreased speleothem wetness.

  2. Strategic Petroleum Reserve, West Hackberry oil storage cavern fire and spill of September 21, 1978: an environmental assessment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, A

    1980-02-29

    This report summarizes an environmental assessment of the fire and oil spill at the Strategic Petroleum Reserve site, West Hackberry, Louisiana. Subjective identification of oil contaminated habitats was supported by a more rigorous classification of samples utilizing discriminant analysis. Fourteen contaminated stations were identified along the shore of Black Lake just north and west of Wellpad 6, encompassing approximately 9 hectares. Seasonal variation in the structures of marsh and lake bottom communities in this contaminated area were not generally distinguishable from that of similar communities in uncontaminated habitats along the southern and southeastern shores of Black Lake. The major impact of spilled oil on the marsh vegetation was to accelerate the natural marsh deterioration which will eventually impact animals dependent on marsh vegetation for habitat structure. Vanadium, the predominate trace metal in the oil, and pyrogenic products due to the fire were found at the most distant sampling site (5 km) from Cavern 6 during Phase I, but were not detected downwind of the fire in excess of background levels in the later phases. Remote sensing evaluation of vegetation under the plume also indicated that stress existed immediately after the fire, but had disappeared by the end of the 1-year survey.

  3. The Role of Hemosiderin Excision in Seizure Outcome in Cerebral Cavernous Malformation Surgery: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Ruan, Di; Yu, Xiao-Bo; Shrestha, Sudeep; Wang, Lin; Chen, Gao

    2015-01-01

    Whether the excision of hemosiderin surrounding cerebral cavernous malformations (CCMs) is necessary to achieve a seizure-free result has been the subject of debate. Here, we report a systematic review of related literature up to Jan 1, 2015 including 594 patients to assess the effect of hemosiderin excision on seizure outcome in patients with CCMs by meta-analysis. Ten studies comparing extended hemosiderin excision with only lesion resection were identified by searching the English-language literature. Meta-analyses, subgroup analyses and sensitivity analysis were conducted to determine the association between hemosiderin excision and seizure outcome after surgery. Seizure outcome was significantly improved in the patients who underwent an extended excision of the surrounding hemosiderin (OR, 0.62; 95% CI: 0.42-0.91; P = 0.01). In subgroup analysis, studies from Asia (OR, 0.42; 95% CI: 0.25-0.71; P = 0.001), male-majority (female ratio 1 year) before surgery (OR, 0.43; 95% CI: 0.22-0.84; P = 0.01), lesion diameter > 2 cm (OR, 0.41; 95% CI: 0.19-0.87; P = 0.02) and short-term (hemosiderin excision could exhibit significantly improved seizure outcomes compared to patients without hemosiderin excision. However, further well-designed prospective multiple-center RCT studies are still needed.

  4. De novo formation of cerebral cavernous malformation in a patient with intractable epilepsy: case report and review.

    Science.gov (United States)

    Colpan, Mustafa Efkan; Uckardesler, Levent; Sekerci, Zeki; Slavin, Konstantin

    2010-07-01

    The exact origin and process of development of cerebral cavernous malformations (CCMs) is currently unknown. In this article, the authors present de novo CCM formation in a patient with intractable epilepsy and discuss the pathogenesis of CCM in light of several current theories. A 34-year-old man presented with a 10-year history of intractable seizures. His neurological examination was normal, and the initial magnetic resonance imaging (MRI) was suggestive of right mesial temporal sclerosis (MTS). Follow-up MRI study showed development of CCM in the right frontal region. Subsequently, invasive monitoring revealed right temporal seizure source, prompting right temporal lobectomy that resulted in abolition of epilepsy. Histological diagnosis of CCM was confirmed after the lesion was removed in a separate surgery. The patient recovered to normal lifestyle without any complications. This appears to be a first documented case of de novo CCM formation in the setting of intractable epilepsy with ipsilateral MTS. Since the possibility of lesion development cannot be ruled out based on clinical examination, updated imaging and thorough neurophysiological workup are needed for successful treatment of patients with intractable epilepsy.

  5. Clinical and angiographic characteristics of cavernous sinus dural arteriovenous fistulas manifesting as venous infarction and/or intracranial hemorrhage

    International Nuclear Information System (INIS)

    Miyamoto, Naoko; Naito, Isao; Takatama, Shin; Shimizu, Tatsuya; Iwai, Tomoyuki; Shimaguchi, Hidetoshi

    2009-01-01

    Cavernous sinus (CS) dural arteriovenous fistulas (DAVFs) rarely cause venous infarction (VI) and/or intracranial hemorrhage (ICH) despite the presence of cortical venous drainage (CVD). The present study investigated the characteristics of CS DAVFs manifesting as VI/ICH. Fifty-four patients treated for CS DAVFs were retrospectively studied. Six patients presented with VI/ICH. Two of the three patients presenting with ICH had CVD only to the superficial sylvian vein (SSV) or the deep sylvian vein (DSV). Three patients presenting with VI had multiple drainages, and angiography of these patients showed a varix on the SSV, drainage into the DSV with agenesis of the second and third segment of basal vein of Rosenthal, and thrombosis of the distal petrosal vein. CS DAVF with CVD only carries higher risk of VI/ICH than multiple drainages. Many CS DAVFs presenting with VI, especially those with drainage into the petrosal vein, have multiple drainages in the early stage. Thrombosis of the inferior and superior petrosal sinuses and superior orbital vein gradually increases pressure of the CVD, and then, VI may occur. In contrast, CS DAVFs with CVD only from the beginning, common in the patients with drainage into the SSVs and DSVs, are likely to cause ICH. Angiographic risk factors causing VI/ICH are CVD only, varix formation, agenesis of the second and third segment of basal vein of Rosenthal, and thrombosis of the superior orbital vein, lateral half of the superior petrosal sinus, and distal CVD. (orig.)

  6. Clinical and angiographic characteristics of cavernous sinus dural arteriovenous fistulas manifesting as venous infarction and/or intracranial hemorrhage

    Energy Technology Data Exchange (ETDEWEB)

    Miyamoto, Naoko; Naito, Isao; Takatama, Shin; Shimizu, Tatsuya; Iwai, Tomoyuki [Geriatrics Research Institute and Hospital, Department of Neurosurgery, Maebashi (Japan); Shimaguchi, Hidetoshi [Gunma University Graduate School of Medicine, Department of Neurosurgery, Maebashi (Japan)

    2009-01-15

    Cavernous sinus (CS) dural arteriovenous fistulas (DAVFs) rarely cause venous infarction (VI) and/or intracranial hemorrhage (ICH) despite the presence of cortical venous drainage (CVD). The present study investigated the characteristics of CS DAVFs manifesting as VI/ICH. Fifty-four patients treated for CS DAVFs were retrospectively studied. Six patients presented with VI/ICH. Two of the three patients presenting with ICH had CVD only to the superficial sylvian vein (SSV) or the deep sylvian vein (DSV). Three patients presenting with VI had multiple drainages, and angiography of these patients showed a varix on the SSV, drainage into the DSV with agenesis of the second and third segment of basal vein of Rosenthal, and thrombosis of the distal petrosal vein. CS DAVF with CVD only carries higher risk of VI/ICH than multiple drainages. Many CS DAVFs presenting with VI, especially those with drainage into the petrosal vein, have multiple drainages in the early stage. Thrombosis of the inferior and superior petrosal sinuses and superior orbital vein gradually increases pressure of the CVD, and then, VI may occur. In contrast, CS DAVFs with CVD only from the beginning, common in the patients with drainage into the SSVs and DSVs, are likely to cause ICH. Angiographic risk factors causing VI/ICH are CVD only, varix formation, agenesis of the second and third segment of basal vein of Rosenthal, and thrombosis of the superior orbital vein, lateral half of the superior petrosal sinus, and distal CVD. (orig.)

  7. Cryogenic fracturing of calcite flowstone in caves: theoretical considerations and field observations in Kents Cavern, Devon, UK

    Directory of Open Access Journals (Sweden)

    Lundberg Joyce

    2012-07-01

    Full Text Available Several caves in Devon, England, have been noted for extensive cracking of substantial flowstone floors. Conjectural explanations have included earthquake damage, local shock damage from collapsing cave passages, hydraulic pressure, and cryogenic processes. Here we present a theoretical model to demonstrate that frost-heaving and fracture of flowstone floors that overlie wet sediments is both a feasible and likely consequence of unidirectional air flow or cold-air ponding in caves, and argue that this is the most likely mechanism for flowstone cracking in caves located in Pleistocene periglacial environments outside of tectonically active regions. Modeled parameters for a main passage in Kents Cavern, Devon, demonstrate that 1 to 6 months of -10 to -15° C air flow at very modest velocities will result in freezing of 1 to 3 m of saturated sediment fill. The resultant frost heave increases with passage width and depth of frozen sediments. In the most conservative estimate, freezing over one winter season of 2 m of sediment in a 6-m wide passage could fracture flowstone floors up to ~13 cm thick, rising to ~23 cm in a 12-m wide passage. Natural flaws in the flowstone increase the thickness that could be shattered. These numbers are quite consistent with the field evidence.

  8. Practical experience with gas permeability tests by the new SoMIT method in Etzel cavern field; Praktische Erfahrungen mit Gasdichtheitstests nach dem neuen SoMIT-Verfahren im Kavernenfeld Etzel

    Energy Technology Data Exchange (ETDEWEB)

    Boor, S.; Huebner, S. [KBB Underground Technologies GmbH, Hannover (Germany); Schweinsberg, H.J. [IVG Logistik GmbH, Bonn (Germany); Tryller, H. von [SOCON, Giessen (Germany)

    2007-09-13

    In the course of restructuring and extension measures in the Etzel cavern field, IVG Logistik GmbH has been retrofitting oil storage caverns into gas storage caverns since November 2005. Before completion can be started, gastightness of all wells had to be checked. This was done, for the first time, using the SoMIT (Sonar Mechanical Integrity Testing) process in which the level is gauged continuously by an ultrasonic probe. This method is more accurate by about a power of ten than the conventional gamma-gamma probe. Further, continuous measurement enables in-time evaluation of trends. As IVG had good results with the conventional test method in Etzel cavern field, the higher accuracy of the SoMIT method was used for shortening the test time and achieving a cost reduction. SoMIT also has operative advantages. For example, there are no repeated measurements which would require resetting of the probe to the reference depth and might also cause measuring errors. Further, the measurements are not influenced by oil residues in the cavern as the ultrasonic probe is used above the fluid level. (orig.)

  9. Multiple cerebral cavernous malformations: typical pattern on MR imaging and appearance of a new lesion in the follow-up MRI; Multiple zerebrale kavernoese Angiome - Klassischer MRT-Befund mit Nachweis einer de-novo Gefaessmalformation im Verlauf

    Energy Technology Data Exchange (ETDEWEB)

    Kuhn, J.; Bewermeyer, H. [Neurologische Klinik, Kliniken der Stadt Koeln, Krankenhaus Merheim (Germany); Knitelius, H.O. [Radiologische Klinik, Kliniken der Stadt Koeln, Krankenhaus Merheim (Germany)

    2004-07-01

    Cerebral cavernous malformations (CCM) are common, mostly benign vascular anomalies of the CNS. Clinical features are seizures, headache and focal neurological signs. Often they are asymptomatic. Apart from sporadically cases CCM occur as an autosomal dominant condition. Familial cases are associated with a high frequency of multiple lesions. MRI is most sensitive in the detection of cavernous malformations. The MRI findings of CCM are variable, depending on hemorrhage and calcifications. The typical appearance of CCM are heterogenous ''popcorn-like'' lesions of different size with a mixed signal core and a hypointense hemosiderin rim. Our report concerns a 22 year old man with multiple cerebral cavernous malformations whose follow-up MRI of brain showed the appearance of a new lesion. (orig.)

  10. [De Novo Cavernous Angioma Secondary to a Developmental Venous Anomaly:A Case Report and Review of the Literature].

    Science.gov (United States)

    Sakakibara, Yohtaro; Taguchi, Yoshio; Nakamura, Homare; Onodera, Hidetaka; Uchida, Masashi; Kawaguchi, Kimiyuki; Aida, Yoshio

    2017-04-01

    Previously, cavernous angiomas(CAs)have been thought to be only congenital in origin. Recently, however, a few cases of de novo CAs have been reported in the literature. We present a case of a de novo CA and discuss the etiology of the newly appeared CA. A 29-year-old man was presented to a local clinic because of hypersomnia. MRI demonstrated a heterogeneous mass peripherally located, which was in contact with a developmental venous anomaly(DVA)at the left thalamus. Six years before the presentation, he visited the same clinic because of faintness, and MRI results indicated no abnormality except for the DVA. Three weeks later, he suddenly experienced difficulty in speech, and the MRI revealed an increase in the size of the mass. Subsequently, he was admitted at our institution, and neurological examination revealed aphasia and right hemiparesis. A left carotid angiogram on venous phase showed a narrowing of the DVA, which was seen as it entered the internal cerebral vein. The diagnosis of a de novo CA was made. The mass was completely resected through the transcallosal transventricular approach to avoid injuring the DVA. The DVA could not be found during surgery. The pathological diagnosis was in line with the findings of CA. Postoperatively, the patient continued having difficulty in speech and was transferred to another institution for speech rehabilitation. Although the association of CA and DVA has been described with increasing frequencies recently, the etiology of de novo CA in the case of this association has been a matter of debate. In the present case, it was speculated that a narrowing of the DVA resulted in increased venous pressure and caused the development of de novo CA.

  11. Preoperative Lateralization Modalities for Cushing Disease: Is Dynamic Magnetic Resonance Imaging or Cavernous Sinus Sampling More Predictive of Intraoperative Findings?

    Science.gov (United States)

    Sun, Hai; Yedinak, Chris; Ozpinar, Alp; Anderson, Jim; Dogan, Aclan; Delashaw, Johnny; Fleseriu, Maria

    2015-06-01

    Objective To analyze whether cavernous sinus sampling (CSS) and dynamic magnetic resonance imaging (dMRI) are consistent with intraoperative findings in Cushing disease (CD) patients. Design Retrospective outcomes study. Setting Oregon Health & Science University; 2006 and 2013. Participants A total of 37 CD patients with preoperative dMRI and CSS to confirm central adrenocorticotropic hormone (ACTH) hypersecretion. Patients were 78% female; mean age was 41 years (at diagnosis), and all had a minimum of 6 months of follow-up. Main Outcome Measures Correlations among patient characteristics, dMRI measurements, CSS results, and intraoperative findings. Results All CSS indicated presence of CD. Eight of 37 patients had no identifiable tumor on dMRI. Three of 37 patients had no tumor at surgery. dMRI tumor size was inversely correlated with age (rs = - 0.4; p = 0.01) and directly correlated to intraoperative lateralization (rs = 0.3; p < 0.05). Preoperative dMRI was directly correlated to intraoperative lateralization (rs = 0.5; p < 0.002). CSS lateralization showed no correlation with intraoperative findings (rs = 0.145; p = 0.40) or lateralization observed on preoperative dMRI (rs = 0.17; p = 0.29). Postoperative remission rate was 68%. Conclusion dMRI localization was most consistent with intraoperative findings; CSS results were less reliable. Results suggest that small ACTH-secreting tumors continue to pose a challenge to reliable preoperative localization.

  12. The Role of Hemosiderin Excision in Seizure Outcome in Cerebral Cavernous Malformation Surgery: A Systematic Review and Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Di Ruan

    Full Text Available Whether the excision of hemosiderin surrounding cerebral cavernous malformations (CCMs is necessary to achieve a seizure-free result has been the subject of debate. Here, we report a systematic review of related literature up to Jan 1, 2015 including 594 patients to assess the effect of hemosiderin excision on seizure outcome in patients with CCMs by meta-analysis.Ten studies comparing extended hemosiderin excision with only lesion resection were identified by searching the English-language literature. Meta-analyses, subgroup analyses and sensitivity analysis were conducted to determine the association between hemosiderin excision and seizure outcome after surgery.Seizure outcome was significantly improved in the patients who underwent an extended excision of the surrounding hemosiderin (OR, 0.62; 95% CI: 0.42-0.91; P = 0.01. In subgroup analysis, studies from Asia (OR, 0.42; 95% CI: 0.25-0.71; P = 0.001, male-majority (female ratio 1 year before surgery (OR, 0.43; 95% CI: 0.22-0.84; P = 0.01, lesion diameter > 2 cm (OR, 0.41; 95% CI: 0.19-0.87; P = 0.02 and short-term (< 3 years follow-up (OR, 0.48; 95% CI: 0.29-0.80; P = 0.005 tended to correlate with a significantly favorable outcome.Patients who underwent extended surrounding hemosiderin excision could exhibit significantly improved seizure outcomes compared to patients without hemosiderin excision. However, further well-designed prospective multiple-center RCT studies are still needed.

  13. Difference of language cortex reorganization between cerebral arteriovenous malformations, cavernous malformations, and gliomas: a functional MRI study.

    Science.gov (United States)

    Deng, Xiaofeng; Xu, Long; Zhang, Yan; Wang, Bo; Wang, Shuo; Zhao, Yuanli; Cao, Yong; Zhang, Dong; Wang, Rong; Ye, Xun; Wu, Jun; Zhao, Jizong

    2016-04-01

    The authors attempted to demonstrate the difference in language cortex reorganization between cerebral malformations (AVMs), cavernous malformations (CMs), and gliomas by blood oxygen level-dependent (BOLD) functional magnetic resonance imaging. Clinical and imaging data of 27 AVM patients (AVM-L group), 29 CM patients (CM-L group), and 20 glioma patients (Glioma-L group) were retrospectively reviewed, with lesions overlying the left inferior frontal gyrus (Broca area). As a control, patients with lesions involving the right inferior frontal gyrus were also enrolled, including 14 AVM patients (AVM-R group), 20 CM patients (CM-R group), and 14 glioma patients (Glioma-R group). All patients were right-handed. Lateralization indices (LI) of BOLD signal activations were calculated separately for Broca and Wernicke areas. In AVM-L group, right-sided lateralization of BOLD signals was observed in 10 patients (37.0%), including 6 in the Broca area alone, 1 in the Wernicke area alone, and 3 in both areas. Three patients (10.3%) of CM-L group showed right-sided lateralization in both Broca and Wernicke areas, and 1 patient (5.0%) of Glioma-L group had right-sided lateralization in the Wernicke area alone. A significant difference of right-sided lateralization was observed between the AVM-L group and CM-L group (P = 0.018) and also between the AVM-L group and Glioma-L group (P = 0.027). No patient in AVM-R, CM-R, or Glioma-R groups showed right-sided lateralization. Language cortex reorganization may occur in AVM, CM, and glioma patients when the traditional language cortex was involved by lesions, but the potential of reorganization for CM and glioma patients seems to be insufficient compared with AVM patients.

  14. Frequency of arteriovenous shunts in hepatic cavernous hemangiomas in adults as seen on selective arteriography and postembolization radiography.

    Science.gov (United States)

    Ouyang, Y; Ouyang, X H; Yu, M; Gu, S B

    2001-01-01

    To study the frequency and angiographic findings of arteriovenous shunts (AVS) associated with adult cavernous hemangiomas of the liver (CHL) on hepatic artery digital subtraction angiography (DSA) and optimize the imaging technique of DSA to improve its diagnostic efficacy. We retrospectively analyzed 43 intraarterial DSA procedures performed on 30 adults with CHL. Of the 30 patients 22 were found to have an AVS. Transcatheter arterial embolization with Lipiodol (L-TAE) was performed on 21 of these and radiographs were taken immediately after embolization to observe the distribution of the injected iodized oil. The results were compared with those of the AVS found on DSA images. AVS were identified by DSA in 22 (73.3%) of 30 patients. All AVS were located in the peritumoral liver tissue and had a parallel track appearance, or early filling of small draining veins during the arterial phase of DSA. Radiographs taken immediately after L-TAE in 21 of the 22 cases with AVS showed iodized oil filling a few portal branches or draining veins as a result of incompletely occluded shunts in 11 patients. In 10 patients there was complete occlusion and no filling of any vein, or only the originating end of draining veins filled with iodized oil. No evidence of AVS was found in the other eight patients in this series, and in six of these the DSA was not considered diagnostic. The present study indicates that AVS are frequently seen in adults with CHL. DSA with high-quality images is helpful in identifying small AVS of CHL. The formation of an AVS in CHL may be closely related to the pathological changes in the peritumoral liver tissue.

  15. Sensory function after cavernous haemangioma: a case report of thermal hypersensitivity at and below an incomplete spinal cord injury.

    Science.gov (United States)

    Gómez-Soriano, J; Goiriena, E; Florensa-Vila, J; Gómez-Arguelles, J M; Mauderli, A; Vierck, C J; Albu, S; Simón-Martinez, C; Taylor, J

    2012-09-01

    Case report of a 42-year-old woman with non-evoked pain diagnosed with a cavernous C7-Th6 spinal haemangioma. To assess the effect of intramedullary haemorrhage (IH) on nociception and neuropathic pain (NP) at and below an incomplete spinal cord injury (SCI). Sensorimotor Function Group, Hospital Nacional de Parapléjicos de Toledo (HNPT). T2*-susceptibility weighted image (SWI) magnetic resonance imaging (MRI) of spinal haemosiderin and a complete pain history were performed 8 months following initial dysaesthesia complaint. Thermal pain thresholds were assessed with short 1 s stimuli, while evidence for central sensitization was obtained with psychophysical electronic Visual Analogue Scale rating of tonic 10 s 3 °C and 48 °C stimuli, applied at and below the IH. Control data were obtained from 10 healthy volunteers recruited from the HNPT. Non-evoked pain was present within the Th6 dermatome and lower legs. T2*-SWI MRI imaging detected extensive haemosiderin-rich IH (C7-Th5/6 spinal level). Cold allodynia was detected below the IH (left L5 dermatome) with short thermal stimuli. Tonic thermal stimuli applied to the Th6, Th10 and C7 dermatomes revealed widespread heat and cold allodynia. NP was diagnosed following IH, corroborated by an increase in below-level cold pain threshold with at- and below-level cold and heat allodynia. Psychophysical evidence for at- and below-level SCI central sensitization was obtained with tonic thermal stimuli. Early detection of IH could lead to better management of specific NP symptoms, an appreciation of the role of haemorrhage as an aggravating SCI physical factor, and the identification of specific spinal pathophysiological pain mechanisms.

  16. 2nd February 2011-Vice-Chancellor of Jammu University-Prof. Varun Sahni-India visiting ALICE cavern and LHC Tunnel

    CERN Multimedia

    Sylvain Chapeland

    2011-01-01

    Photo 1-2,4-8:The delegation visiting the ATLAS cavern Photo 3:ALICE Collaboration Spokesperson P. Giubellino+ALICE Collaboration University of Jammu S. Mahajan+ALICE Collaboration University of Jammu A. Bhasin+ALICE Collaboration Universita degli Studi di Torino R. Bala+V. Sahni+Adviser for India R.Voss+S. Arriaga+ALICE Collaboration University of Jammu A. Gupta Photo 9-13:The delegation visiting the LHC tunnel at Point 2 Photo 14-22: Signature of the Guest Book with R. Voss

  17. 2 April 2014 - H. E. Mr Joachim Gauck, President of the Federal Republic of Germany in the ATLAS experimental cavern with Director-General R. Heuer.

    CERN Multimedia

    Brice, Maximilien

    2014-01-01

    in the ATLAS cavern: Minister of State at the Federal Foreign Office M. Böhmer (green jacket) and Mrs daniela Schadt (First Lady). 201404-069_39.jpg: State Secretary, Federal Ministry of Education and Research G. Schütte, Minister of State at the Federal Foreign Office M. Böhmer, President Gauck, CERN DG, State Secretary, Chief of the Federal President´s Office D. Gill and Ambassador of the Federal Republic of Germany to the Swiss Confederation O. Lampe.

  18. Dedication of the massive ATLAS art mural painted by Josef Kristofoletti directly above the cavern of the ATLAS Experiment at CERN

    CERN Multimedia

    Claudia Marcelloni, Michael Barnett

    2010-01-01

    Ceremony to celebrate the massive mural of the ATLAS detector at CERN painted by artist Josef Kristofoletti. The mural is located at the ATLAS Experiment site, and it shows on two perpendicular walls the detector with a collision event superimposed. The event on the large wall shows a simulation of an event that would be recorded in ATLAS if a Higgs boson was produced. The cavern of the ATLAS Experiment with the detector is 100 meters directly below the mural. The height of the mural is about 12 meters (40 feet). The actual ATLAS detector is more than twice as big.

  19. Giant cavernous malformation in the ventrolateral midbrain with extension into the thalamus: a case report of a paramedian supracerebellar transtentorial approach.

    Science.gov (United States)

    Duan, Hongzhou; Hara, Yosuke; Goto, Tetsuya; Chiba, Akihiro; Hongo, Kazuhiro

    2016-08-01

    Cavernous malformations (CMs) of the midbrain and thalamus are relatively rare and particularly difficult to be resected given their location in eloquent tissues. Here, we report a case of a 14-year-old boy who experienced repeated and progressive right hemiparesis. Image examinations showed a gradually enlarged CM originated in the left ventrolateral midbrain extending to the left thalamus with repeated hemorrhage. By performing a paramedian supracerebellar transtentorial approach, the CM was totally removed, and the patient recovered without any new neurological deficit. The authors' experience suggests that this approach is eminent in treating giant lesions involving the ventrolateral midbrain and thalamus.

  20. Pore pressure measurement plan of near field rock used on three dimensional groundwater flow analysis in demonstration test of cavern type disposal facility

    International Nuclear Information System (INIS)

    Onuma, Kazuhiro; Terada, Kenji; Matsumura, Katsuhide; Koyama, Toshihiro; Yajima, Kazuaki

    2008-01-01

    Demonstration test of underground cavern type disposal facilities is planed though carrying out construction of full scale engineering barrier system which simulated in the underground space in full scale and under actual environment. This test consists of three part, these are construction test, performance test and measurement test. Behavior of near field rock mass is measured about hydrological behavior under and after construction to evaluate effect at test facility. To make plan of pore pressure measurement, three dimensional groundwater flow analysis has been carried out. Based on comparison of analysis before and after test, detail plan has been studied. (author)

  1. Epistaxis revealing the rupture of a carotid aneurysm of the cavernous sinus extending into the sphenoid: treatment using an uncovered stent and coils. Review of literature.

    Science.gov (United States)

    Lehmann, Pierre; Saliou, Guillaume; Page, Cyril; Balut, Antonia; Le Gars, Daniel; Vallée, Jean Noel

    2009-05-01

    True carotid aneurysms with sphenoid extension and revealed by epistaxis are rare. A review of the literature shows the mortality risk of this pathology and the different therapeutic options. A 41-year-old female presented with a cavernous carotid aneurysm with sphenoid extension revealed by massive epistaxis. We propose a combined treatment of the affected vessel using coils and an uncovered stent. The first stage to stop the hemorrhages and occlude the aneurysm using the coil and the second stage several days later after anticoagulation using the stent to prevent revascularization. This treatment has been shown to be effective in producing immediate hemostasis and stable long-term occlusion.

  2. Cavernous body reduction in four patients with erectile dysfunction due to insufficient venous occlusion and a deficit of elastic fibers in the tunica albugínea

    Directory of Open Access Journals (Sweden)

    Fabrizio Iacono

    2007-12-01

    Full Text Available INTRODUCTION: The corpora cavernosa are cylindrical vessels containing fluid under pressure. Thus, if cavernous wall resistance decreases, the radius increases and internal pressure decreases (LaPlace's law. We reasoned that if we decrease the corpus cavernosum radius, by excising a strip from each tunica albuginea, intracavernous pressure would increase during erection. MATERIALS AND METHODS: We treated with this procedure, four patients (mean age 41.5 with long-standing erectile dysfunction due to veno-occlusive dysfunction, non-responders to phosphodiesterase-5 inhibitors and intracavernous PGE1 injection. RESULTS: Two months post-surgery, intracavernous PGE1 (40 mcg induced a satisfactory erection in two patients and a 45% and 58% tumescence in the other two. PGE1 responders also responded to 100 mg sildenafil. After 100 mg sildenafil and 20 mg tadalafil, the two non-responders had erections that enabled penetration but were short lasting. CONCLUSION: The procedure described could be more effective than cavernous revascularization operations. The results seem to confirm the mathematical assumptions.

  3. Treatment of a direct carotid-cavernous fistula in a patient with type IV Ehlers-Danlos syndrome: a novel approach

    Energy Technology Data Exchange (ETDEWEB)

    Hollands, J.K.; Santarius, T.; Kirkpatrick, P.J. [Addenbrooke' s Hospital, Department of Neurosurgery, Cambridge (United Kingdom); Higgins, J.N. [Addenbrooke' s Hospital, Department of Neuroradiology, Cambridge (United Kingdom)

    2006-07-15

    We report a case of a 34-year-old female with type IV Ehlers-Danlos syndrome diagnosed with a carotid cavernous fistula presenting with progressive proptosis. Endovascular embolization using balloons or coils carries a high risk of complications in this group of patients, owing to the extreme fragility of the blood vessels. Initial treatment was conservative until an intracerebral haemorrhage occurred. To avoid transfemoral angiography, the ipsilateral carotid arteries and the internal jugular vein were surgically exposed for insertion of two endovascular sheaths. The patient was transferred from theatre to the angiography suite and the sheaths were used for embolization access. The fistula was closed, with preservation of the carotid artery, using Guglielmi detachable coils deployed in the cavernous sinus from the arterial and venous sides. Rapid resolution of symptoms and signs followed, which was sustained at 6-month follow-up. This technique offers alternative access for endovascular treatment, which may reduce the high incidence of mortality associated with catheter angiography in this condition. (orig.)

  4. Proposal for the award of a contract for the repair work on the endwalls of the UX45 and UX65 caverns

    CERN Document Server

    2001-01-01

    This document concerns the award of a contract for the repair work on the endwalls of the UX 45 and UX 65 caverns in the LHC tunnel. Following a market survey carried out among 39 firms in ten Member States, a call for tenders (IT-2886/ST/LHC) was sent on 22 January 2001 to seven firms and two consortia, each consisting of three firms, in six Member States. By the closing date, CERN had received four tenders from two firms and two consortia in three Member States. The Finance Committee is invited to agree to the negotiation of a contract with CONRAD ZSCHOKKE (CH), the lowest bidder complying with the technical requirements, for the repair work on the endwalls of the UX 45 and UX 65 caverns for a total amount of 1 734 340 Swiss francs, not subject to revision until 31 December 2002. The firm has indicated the following distribution by country of the contract value covered by this adjudication proposal: CH - 100%.

  5. Flow diversion in vasculitic intracranial aneurysms? Repair of giant complex cavernous carotid aneurysm in polyarteritis nodosa using Pipeline embolization devices: first reported case.

    Science.gov (United States)

    Martinez Santos, Jaime; Kaderali, Zul; Spears, Julian; Rubin, Laurence A; Marotta, Thomas R

    2016-07-01

    Intracranial aneurysms in polyarteritis nodosa (PAN) are exceedingly rare lesions with unpredictable behavior that pose real challenges to microsurgical and endovascular interventions owing to their inflammatory nature. We introduce a safe and effective alternative for treating these aneurysms using Pipeline embolization devices (PEDs). A 20-year-old man presented with diplopia, headaches, chronic abdominal pain, and weight loss. Diagnostic evaluations confirmed PAN, including bilateral giant cavernous carotid aneurysms. Cyclophosphamide and steroids achieved significant and sustained clinical improvement, with a decision to follow the aneurysms serially. Seven years later the left unruptured aneurysm enlarged, causing a sudden severe headache and a cavernous sinus syndrome. Treatment of the symptomatic aneurysm was pursued using flow diversion (PED) and the internal carotid artery was successfully reconstructed with a total of four overlapping PEDs. At 6 months follow-up, complete exclusion of the aneurysm was demonstrated, with symptomatic recovery. This is the first description of using a flow-diverting technique in an inflammatory vasculitis. In this case, PEDs not only attained a definitive closure of the aneurysm but also reconstructed the damaged and fragile arterial segment affected with vasculitis. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  6. ATLAS cavern hand-over ceremony on 4th June 2003 in the presence of the President of the Swiss Confederation

    CERN Multimedia

    Jenni, P

    The 4th of June 2003 will be remembered as a very major milestone in the history of the ATLAS detector construction. In the presence of the President of the Swiss Confederation, Mr. Pascal Couchepin, the ATLAS cavern was handed over by the CERN Director-General, Professor Luciano Maiani, to the Collaboration. For this highly press-mediated event the CERN Director-General had invited some 100 political personalities and representatives from the Geneva and the neighbouring French regions, and from CERN Member and Non-Member States. The surface building was transformed for this occasion into an attractive multi- media hall with films and exhibitions from ATLAS and the civil engineering, with a bar and the CERN jazz band. Besides of course the cavern itself, the Swiss President visited also the ATLAS barrel toroid magnet and the LAr calorimeter assembly activities in Hall 180. The Swiss President visiting the Barrel Toroid integration work in Hall 180 He was very interested and impressed by these, aski...

  7. 3 May 2014 - His Excellency Dr Karolos Papoulias President of the Hellenic Republic in the LHC tunnel at Point 1 and in ATLAS experimental cavern with Director-General R. Heuer.

    CERN Multimedia

    Brice, Maximilien

    2014-01-01

    In the LHC tunnel at Point 1: Beams Department, Controls Group Leader E. Hatziangeli and Technology Department, Cryogenics Group Deputy Leader D. Delikaris. In the ATLAS cavern: ATLAS Deputy Spokesperson B. Heinemann and ATLAS Collaboration National contact person and CAST Collaboration National Technical University of Athens Team Leader E. Gazis.

  8. Countercurrent transfer of 125I-LHRH in the perihypophyseal cavernous sinus-carotid rete vascular complex, demonstrated on isolated pig heads perfused with autologous blood.

    Science.gov (United States)

    Grzegorzewski, W J; Skipor, J; Wasowska, B; Krzymowski, T

    1997-05-01

    The objective of the study was to determine whether the local permeability of luteinizing hormone-releasing hormone (LHRH) from the venous blood of the perihypophyseal cavernous sinus into the arterial blood of the carotid rete, supplying the brain and hypophysis in gilts, depends on the day of the estrous cycle, as well as to determine whether this transfer exists when LH concentration in the blood is reduced (the experimental short-loop negative feedback for LH secretion after estradiol injection in ovariectomized gilts). Experiments were conducted on isolated gilt heads with necks, on chosen days of the estrous cycle (n = 40), and on previously ovariectomized gilts treated with estradiol benzoate (EB) (n = 5) or corn oil (n = 3). After exsanguination, the gilt heads with necks were disarticulated and about 30-45 min later were supplied with autologous, oxygenated, and heated blood at a stable blood flow and pressure through the left carotid artery for 30 min. 125I-LHRH was infused into both cavernous sinuses through the cannulated angularis oculi veins for 5 min. After 125I-LHRH infusion, radiolabeled LHRH was found (P gilts), on Days 12-14 (seven gilts) of the estrous cycle, and in five ovariectomized gilts during negative feedback for LH surge (40 hr after EB). No significant radioactivity of 125I-LHRH was found in the arterial blood on Days 3-5 (n = 6), 9-11 (n = 4), and 15-21 (n = 17) of the estrous cycle. A very low level of radioactivity was found in the ovariectomized control group after the injection of corn oil (n = 3). These results provide evidence for the permeability of LHRH from the venous to the arterial blood and its retrograde transport with the arterial blood to the hypophysis and brain, after the ovulation period (Days 1-2) and on Days 12-14 of the estrous cycle. This suggests that a close relationship exists between the day of the estrous cycle and LHRH permeability from the venous to the arterial blood in the perihypophyseal cavernous sinus

  9. Cerebral Cavernous Malformation

    Science.gov (United States)

    ... those areas not involved with motor function, speech, vision, hearing, memory, and learning) are very likely to be candidates ... those areas not involved with motor function, speech, vision, hearing, memory, and learning) are very likely to be candidates ...

  10. Cavernous Angioma and Children

    Science.gov (United States)

    ... physician indicating the medical necessity of the placement, tuition for this kind of private school can be tax deductible as a medical expense. With a great deal of advocating, and perhaps the help of an ... partial tuition compensation from your school district. What should I ...

  11. Usefulness of Preoperative Surgical Simulation with Three-Dimensional Fusion Images for Resection of Cerebral Cavernous Malformations Near Broca’s Area

    Directory of Open Access Journals (Sweden)

    Satoshi Takahashi

    2014-01-01

    Full Text Available Treating subcortical brain lesions in or near eloquent areas is challenging not only because lesions must be resected while preserving brain tissue involved in essential functions, but also because lesions often cannot be easily identified from the surface of the brain. Here, we report 2 cases of cerebral cavernous malformations near Broca’s area. In both cases, lesions were surgically removed by utilizing three-dimensional fusion images created using preoperative magnetic resonance imaging and computed tomography data. Excisions were completed without any worsening of speech function, and the use of presurgical simulations was found to be useful in the design and execution of the actual operations. The technique described in this report serves as a useful tool in simulating surgical strategies by using brain gyri and sulci as surgical landmarks. Furthermore, in contrast to other intraoperative techniques, this method can aid in shortening the duration of surgery and can help limit damage to eloquent areas of the brain.

  12. Transorbital penetrating cerebral injury caused by a wooden stick: surgical nuances for removal of a foreign body lodged in cavernous sinus.

    Science.gov (United States)

    Borkar, Sachin Anil; Garg, Kanwaljeet; Garg, Mayank; Sharma, Bhawani Shankar

    2014-08-01

    Penetrating head injury (PHI) is rare in civilian population and is mostly caused by low-velocity modes. A transorbital penetrating intracranial injury is very rare and more severe than traumatic brain injury. We report a rare case of transorbital penetrating cranial injury caused by a wooden stick. The surgical strategy was planned as the wooden stick was lodged in the right cavernous sinus. The wooden stick was successfully removed. Patient made an uneventful recovery. Transorbital penetrating injuries are uncommon form of injury and require a multidisciplinary approach. No attempt should be made to remove the foreign body without the backup of an operating room because of the possibility that the object may be tamponading an injured vessel. A careful planning and a strict adherence to basic perioperative principles can lead to a satisfactory outcome.

  13. Low androgen induced penile maldevelopment involves altered gene expression of biomarkers of smooth muscle differentiation and a key enzyme regulating cavernous smooth muscle cell tone.

    Science.gov (United States)

    Okumu, Lilian A; Braden, Tim D; Vail, Krystal; Simon, Liz; Goyal, Hari Om

    2014-07-01

    We determined the effects of low androgens in the neonatal period on biomarkers of smooth muscle cell differentiation, Myh11 and Acta2, and on Pde5A expression in the penis. One-day-old pups were treated daily with the gonadotropin-releasing hormone antagonist antide with or without dihydrotestosterone for 1 to 6 days. Tissues were collected at age day 7 and at adulthood at age 120 days. Penes were examined by quantitative reverse transcriptase-polymerase chain reaction, Western blot and immunohistochemistry. Testes were assayed for the intratesticular testosterone and steroidogenic enzymes Cyp17α1 and StAR. Gonadotropin-releasing hormone antagonist exposure suppressed the neonatal testicular testosterone surge 70% to 80%. Quantitative reverse transcriptase-polymerase chain reaction revealed 80% to 90% reductions in Cyp17α1 and StAR protein, and 40% to 60% reductions in Myh11 and ACTA2 as a result of gonadotropin-releasing hormone antagonist compared to controls. Dihydrotestosterone co-administration mitigated these decreases. Western blot confirmed the Myh11 decrease at the protein level. Immunohistochemistry of Acta2 confirmed cavernous smooth muscle cell loss at the tissue level. Also, gonadotropin-releasing hormone antagonist exposure decreased Pde5a expression and dihydrotestosterone co-administration mitigated the decrease. Comparison of data between 2 parts of the penis body (corpora cavernosa and corpus spongiosum) showed that antagonist induced decreases in Myh11, Acta2 and Pde5a expression occurred only in the corpora cavernosa, implying that the latter is the target site of low androgen action. As evidenced by gonadotropin-releasing hormone antagonist induced suppression of the neonatal testosterone surge and reduced steroidogenesis, low androgens in the neonatal period altered gene expression of biomarkers of smooth muscle cell differentiation. This led to loss of cavernous smooth muscle cells and consequently to penile maldevelopment. Copyright

  14. Spontaneous Regeneration of Nerve Fiber and Irreversibility of Corporal Smooth Muscle Fibrosis after Cavernous Nerve Crush Injury: Evidence From Serial Transmission Electron Microscopy and Intracavernous Pressure.

    Science.gov (United States)

    Wu, Yi-No; Chen, Kuo-Chiang; Liao, Chun-Hou; Chiang, Han-Sun

    2017-10-16

    To determine the pathophysiological progresses following bilateral cavernous nerve crushing (BCNC) injury, as an index for a treatment point and establishment of adequate treatment strategies for neurogenic erectile dysfunction (ED). Thirty-six rats were assigned to 1 of 6 groups, and BCNC or sham surgery was performed. Functional testing and ultrastructural analyses were performed immediately and at 7, 14, 21, and 28 d after the cavernous nerve (CN) injury (n = 6). Intracavernos pressure lowered progressively from 7 d to 14 d post-injury, and histological staining revealed that the number of neuronal nitric oxide synthase-positive nerve fibers on the dorsal penile nerve decreased significantly and progressively from 7 d until 21 d post-injury. Furthermore, ultrastructural analyses revealed axon loss and demyelination of the CN at 7 and 14 d post-injury. However, it is followed by partial spontaneous recovery of erectile function and regeneration of the CN at 28 d post-injury, suggesting that these time points may be useful for evaluating the effects of drug treatments. Furthermore, we found that CN injury-induced damage to corporal smooth muscle cells was irreversible; therefore, focusing on protecting the corpus cavernosum from apoptosis may be more important than nerve protection when assessing treatment mechanisms in the CN injury model. Our study makes a significant contribution to the human diagnostic pathology literature because it describes characteristics of relevant tissue in the rat, and provides information regarding time points that may be useful for future studies of pathological mechanisms or treatment evaluations. Copyright © 2017. Published by Elsevier Inc.

  15. State of the art for fabricating and emplacing concrete containers into large horizontal disposal caverns in the french geological repository - 59267

    International Nuclear Information System (INIS)

    Bosgiraud, Jean-Michel; Guariso, Maurice; Pineau, Francois

    2012-01-01

    The research and development work presented in this paper was initialized by Andra in 2007. The work necessary for manufacturing and testing a full scale demonstrator is presently implemented. The case story is twofold. The first part is related to the initial development of a high performance concrete formulation used for fabricating concrete storage containers (containing Intermediate Level and Long Lived Waste primary canisters) to be stacked and emplaced into 400-m long concrete lined horizontal disposal vaults (also called cavern), excavated in the Callovo-Oxfordian clay host formation at a 550 to 600-m depth, with an inside diameter of approximately 8-m. The fabrication of the concrete boxes is illustrated. The second part presents the outcome at the end of the detailed design phase, for a system which is now being manufactured (for further test and assembly), for the emplacement of the concrete containers inside the vault. The application was engineered for remote emplacing a pile of 2 concrete containers (the containers are preliminarily stacked in a pile of 2, inside a hot cell, thanks to a ground travelling gantry crane). The emplacement process is justified and the related emplacement synoptic is illustrated. The test campaign is scheduled in 2011-2012. The successful completion of the technical trials is mandatory to confirm the mechanical feasibility of remotely emplacing concrete containers into large horizontal disposal caverns over long distances. The later display of the machinery at work in Andra's showroom will be instrumental for the confidence building process involving the various stakeholders concerned by the public enquiry period (mid-2013) preceding the deep geological repository license application (2014-2015). (authors)

  16. Complex carotid cavernous sinus fistulas Barrow type D: endovascular treatment via the ophthalmic vein, imaging control with standardized MRI, long-term results

    International Nuclear Information System (INIS)

    Struffert, T.; Grunwald, I.Q.; Reith, W.; Muecke, I.

    2007-01-01

    Purpose: Since feeding arteries from both the internal and external carotid artery are common, cavernous fistulas of Barrow type D are difficult to treat. Embolization using the transarterial approach is considered to be the standard therapy. However, it is often impossible to embolize feeders from the internal carotid artery. The transorbital approach after anterior orbitotomy through the ophthalmic vein is an alternative in this complex situation. The following reports our experience with three female patients who underwent transvenous embolization. Procedural success was documented using standardized MRI and clinical reevaluation. Materials and Methods: Three female patients between 57 and 78 years of age were diagnosed with carotid cavernous fistulas by conventional angiogram. All patients were suffering from exophthalmus and visual impairment. Two patients showed secondary glaucoma and diplopia. In one patient we performed a technically successful transarterial embolization using particles, but no relevant improvement of the patient's condition was seen. Transfemoral transvenous access via the sinus petrosus was not possible in any patient. All patients were then embolized via the ophthalmic vein using GDC detachable coils. All patients were clinically reevaluated by an ophthalmologist. Also a standardized MRI was performed for documentation. Follow-up was performed for the first patient for 32 months, for the second patient for 34 months and for the third patient for 50 months. Results: Transvenous embolization was technically successful in all three cases. Clinical symptoms disappeared rapidly. Postprocedural MRI showed a symmetric diameter of the ophthalmic vein. Venous congestion of the orbit caused by fatty tissue edema regressed completely. Contrast-enhanced magnetic resonance angiography showed normal arterial vessels without evidence of fistula. (orig.)

  17. Stereotactic Radiosurgery for Benign (World Health Organization Grade I) Cavernous Sinus Meningiomas-International Stereotactic Radiosurgery Society (ISRS) Practice Guideline: A Systematic Review.

    Science.gov (United States)

    Lee, Cheng-Chia; Trifiletti, Daniel M; Sahgal, Arjun; DeSalles, Antonio; Fariselli, Laura; Hayashi, Motohiro; Levivier, Marc; Ma, Lijun; Álvarez, Roberto Martínez; Paddick, Ian; Regis, Jean; Ryu, Samuel; Slotman, Ben; Sheehan, Jason

    2018-03-15

    Stereotactic radiosurgery (SRS) has become popular as a standard treatment for cavernous sinus (CS) meningiomas. To summarize the published literature specific to the treatment of CS meningioma with SRS found through a systematic review, and to create recommendations on behalf of the International Stereotactic Radiosurgery Society. Articles published from January 1963 to December 2014 were systemically reviewed. Three electronic databases, PubMed, EMBASE, and The Cochrane Central Register of Controlled Trials, were searched. Publications in English with at least 10 patients (each arm) were included. Of 569 screened abstracts, a total of 49 full-text articles were included in the analysis. All studies were retrospective. Most of the reports had favorable outcomes with 5-yr progression-free survival (PFS) rates ranging from 86% to 99%, and 10-yr PFS rates ranging from 69% to 97%. The post-SRS neurological preservation rate ranged from 80% to 100%. Resection can be considered for the treatment of larger (>3 cm in diameter) and symptomatic CS meningioma in patients both receptive to and medically eligible for open surgery. Adjuvant or salvage SRS for residual or recurrent tumor can be utilized depending on factors such as tumor volume and proximity to adjacent critical organs at risk. The literature is limited to level III evidence with respect to outcomes of SRS in patients with CS meningioma. Based on the observed results, SRS offers a favorable benefit to risk profile for patients with CS meningioma.

  18. Diffuse cavernous hemangioma of the rectum: an atypical cause of rectal bleeding Hemangioma cavernoso difuso del recto: una causa atípica de hemorragia digestiva baja

    Directory of Open Access Journals (Sweden)

    D. Hervías

    2004-05-01

    Full Text Available Objective: cavernous hemangioma of the rectosigmoid colon is a rare disease, with no more than 200 cases reported in the literature. The rectosigmoid is the most common site of this disease in the gastrointestinal tract. Case report: we report the case of a 31-year-old male with recurrent episodes of rectal bleeding, who was finally diagnosed of diffuse cavernous hemangioma of the rectum. The tumor, of 12 x 10 x 9 cm in size, occupied the rectum to the margin of the anal sphincter. A surgical procedure was ruled out because of the inability to carry out a safe anastomosis while preserving anal sphincters. Discussion: rectal hemangiomas are less frequent vascular malformations. The clinical presentation of a cavernous hemangioma of the rectum is usually acute, recurrent or chronic rectal bleeding. Other symptoms stem from the possible compression or invasion of adjacent structures, such as lumbar or perianal pain, metrorrhage, hematuria, etc. This diagnosis is commonly made in younger patients. Colonoscopy is without doubt the diagnostic technique of choice, and it allows to establish the localization, morphology, and total extension of the lesion; its characteristic image is a red-purplish nodule with great vascular congestion. According to the opinion of most authors, biopsy is not advisable during colonoscopy, since imaging techniques are sufficient for an accurate diagnosis, and the risk of bleeding while manipulating this lesion is not negligible. Computed tomography and particularly magnetic resonance imaging, given their high precision to delimit the lesion and its relations to adjacent structures, are imaging studies that are mandatory before surgical treatment. Other techniques such as selective angiography, barium enema, gastrointestinal transit, and upper-tract endoscopy may be supplementary and help locate more lesions along the gastrointestinal tract. Failure to recognize the exact diagnosis and extent of diffuse cavernous hemangioma

  19. Use of MALDI-TOF mass spectrometry and a custom database to characterize bacteria indigenous to a unique cave environment (Kartchner Caverns, AZ, USA).

    Science.gov (United States)

    Zhang, Lin; Vranckx, Katleen; Janssens, Koen; Sandrin, Todd R

    2015-01-02

    MALDI-TOF mass spectrometry has been shown to be a rapid and reliable tool for identification of bacteria at the genus and species, and in some cases, strain levels. Commercially available and open source software tools have been developed to facilitate identification; however, no universal/standardized data analysis pipeline has been described in the literature. Here, we provide a comprehensive and detailed demonstration of bacterial identification procedures using a MALDI-TOF mass spectrometer. Mass spectra were collected from 15 diverse bacteria isolated from Kartchner Caverns, AZ, USA, and identified by 16S rDNA sequencing. Databases were constructed in BioNumerics 7.1. Follow-up analyses of mass spectra were performed, including cluster analyses, peak matching, and statistical analyses. Identification was performed using blind-coded samples randomly selected from these 15 bacteria. Two identification methods are presented: similarity coefficient-based and biomarker-based methods. Results show that both identification methods can identify the bacteria to the species level.

  20. PTEN/PI3K/Akt/VEGF signaling and the cross talk to KRIT1, CCM2, and PDCD10 proteins in cerebral cavernous malformations.

    Science.gov (United States)

    Kar, Souvik; Samii, Amir; Bertalanffy, Helmut

    2015-04-01

    Cerebral cavernous malformations (CCM) are common vascular malformation of the brain and are associated with abnormal angiogenesis. Although the exact etiology and the underlying molecular mechanism are still under investigation, recent advances in the identification of the mutations in three genes and their interactions with different signaling pathways have shed light on our understanding of CCM pathogenesis. The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is known to play a major role in angiogenesis. Studies have shown that the phosphatase and tensin homologue deleted on chromosome ten (PTEN), a tumor suppressor, is an antagonist regulator of the PI3K/Akt pathway and mediates angiogenesis by activating vascular endothelial growth factor (VEGF) expression. Here, we provide an update literature review on the current knowledge of the PTEN/PI3K/Akt/VEGF signaling in angiogenesis, more importantly in CCM pathogenesis. In addition to reviewing the current literatures, this article will also focus on the structural domain of the three CCM proteins and their interacting partners. Understanding the biology of these proteins with respect to their signaling counterpart will help to guide future research towards new therapeutic targets applicable for CCM treatment.

  1. Extended resection of hemosiderin fringe is better for seizure outcome: a study in patients with cavernous malformation associated with refractory epilepsy.

    Science.gov (United States)

    Wang, Xiaoyu; Tao, Zhang; You, Chao; Li, Qiang; Liu, Yi

    2013-01-01

    Cerebral cavernous malformation (CCM) is frequently associated with intractable focal epilepsy. Epileptogenicity is usually attributed to the hemosiderin deposits. Extent of resection is a crucial issue for achieving good seizure outcome. To assess whether seizure outcome is related to the extended resection (ER) of surrounding hemosiderin fringe brain tissue. Between April 2000 and April 2008, 132 patients with CCM and refractory epilepsy were scheduled for surgery based on the high-resolution magnetic resonance imaging (MRI) findings and intensive video-electroencephalogram (EEG) monitoring. All patients underwent pre- and post-operative MRI. Based on MRI findings patients were grouped into: ER group (ER, hemosiderin completely removed) and lesionectomy group (LE, hemosiderin not/partially removed). Post-operative seizure outcome was compared between the two groups based on Engel and the International League Against Epilepsy outcome scales. At 1-year follow-up of the 86 patients in the ER group, 54 (74.4%) achieved seizure free outcome and in the LE group of the 46 patients, 20 (59.5%) achieved seizure-free outcome. At 5-year follow-up, 59.5% (25/42) of patients in ER group and 27.8% (5/18) of patients in LE group achieved seizure-free outcome. ER was not associated with increased neurological morbidity. Our study suggests that complete removal of hemosiderin fringe brain tissue surrounding CCMs may improve short-term and long-term seizure outcome.

  2. Optimal Timing of Surgery for Intramedullary Cavernous Hemangioma of the Spinal Cord in Relation to Preoperative Motor Paresis, Disease Duration, and Tumor Volume and Location.

    Science.gov (United States)

    Imagama, Shiro; Ito, Zenya; Ando, Kei; Kobayashi, Kazuyoshi; Hida, Tetsuro; Ito, Kenyu; Tsushima, Mikito; Ishikawa, Yoshimoto; Matsumoto, Akiyuki; Morozumi, Masayoshi; Tanaka, Satoshi; Machino, Masaaki; Ota, Kyotaro; Nakashima, Hiroaki; Wakao, Norimitsu; Sakai, Yoshihito; Matsuyama, Yukihiro; Ishiguro, Naoki

    2017-05-01

    Prospective study. Investigate factors associated with preoperative motor paresis, recovery, ambulatory status, and intraoperative neurophysiological monitoring (IONM) among patients with no preoperative paresis (N group), complete preoperative motor recovery (CR group), and no complete recovery (NCR group) in patients with intramedullary spinal cavernous hemangioma to determine the optimal timing of surgery. The study evaluated 41 surgical cases in our institute. Disease duration, tumor lesion, manual muscle testing (MMT), and gait at onset, just before surgery, and final follow-up (FU), tumor and lesion volume, IONM, extent of tumor resection, and tumor recurrence were evaluated among N, CR, and NCR groups. Motor paresis at onset was found in 26 patients (63%), with 42% of those in CR group. Disease duration from onset negatively affected stable gait just before surgery and FU as well as lower preoperative MMT ( P preoperative motor paresis to allow optimal surgical outcome. IONM should be carefully monitored in patients with a history of preoperative paresis even with preoperative complete motor recovery.

  3. Rare disorders can be an underlying cause of cyclic vomiting: Familial Mediterranean fever, Helicobacter pylori gastritis, and cavernous transformation of the portal vein.

    Science.gov (United States)

    Egritaş Gürkan, Ödül; Ünlüsoy Aksu, Aysel; Demirtaş, Zeliha; Dalgıç, Buket

    2015-11-01

    Considering the etiology of cyclic vomiting syndrome (CVS) in childhood, a variety of underlying organic causes has been clearly identified in the literature. The aim of this study was to emphasize that endoscopic evaluation in the first step may help diagnosis and treatment in patients with CVS, unlike the CVS-related "North American Society for Pediatric Gastroenterology, Hepatology and Nutrition" (NASPGHAN) consensus statement in 2008. The medical files of patients with vomiting complaints admitted to our tertiary center between the years 2007 and 2012 were analyzed retrospectively. Patients were identified according to the International Classification of Diseases (ICD) codes at their initial presentation, including vomiting. A total of 815 patients with vomiting complaints were evaluated. Of the 379 patients who presented with vomiting only, 336 patients were already being followed for chronic vomiting. Cyclic vomiting was detected in 31 out of 336 patients. In our series, familial Mediterranean fever (FMF), cavernous transformation of the portal vein, and Helicobacter pylori (HP) gastritis presented with CVS for the first time in the pediatric age group. We emphasize that endoscopic evaluation in patients with CVS should be performed as the first step for appropriate diagnosis and treatment.

  4. Evaluation of long-term effect of hepatic arterial embolization with pingyangmycin-lipiodol emulsion in patients with hepatic cavernous hemangiomas

    International Nuclear Information System (INIS)

    Zhang Xuejun; Ouyang Yong; Ma Heping; Chao Lumeng; Zhen Yanli; Gu Subin; Zhou Qunhui; Liu Pengzhi; Wang Hong

    2010-01-01

    Objective: To evaluate the long-term effect of hepatic arterial embolization with pingyanmycin-lipiodol emulsion (PLE) in patients with cavernous hemangiomas of the liver (CHL) and its influence factors. Methods: One hundred and fifty-six hemangiomas that were diagnosed by imaging examinations or confirmed pathologically by surgery in 105 patients with integral follow-up data were analyzed retrospectively in this paper. All hemangiomas were divided into 4 groups according to their size (the largest size of hemangioma) by the authors as follows: A group (≤3 cm, n=25); B group (>3 cm and 2 test respectively. And the influence factors, included of the variant size of hemangiomas, abundant or sparse of abnormal sinusoids and the number of treatment procedures, were also analyzed respectively. Results: The total effective rate of the 156 hemangiomas in 105 patients was 92.95% (145/156). After single procedure of hepatic arterial embolization with PLE, the total effective rate of A and B groups were 100% (57/57), that of C and D groups were 85.86% (85/99), and the difference reach significant (X 2 =8.8553, P 2 =5.2642, P<0.05) than those of group with single procedure (72.73%, 8/11). Conclusions: A best long-term curative effect (complete cure) is usually obtained in the small hemangiomas with abundant abnormal sinusoids, and a satisfactory long-term curative effect can also be achieved in the larger or multiple hemangiomas, particularly in those hemangiomas with abundant abnormal sinusoids by using the repeat procedures of hepatic arterial embolization with PLE. (authors)

  5. Cavernous malformations of the brainstem: three-dimensional-constructive interference in steady-state magnetic resonance imaging for improvement of surgical approach and clinical results.

    Science.gov (United States)

    Zausinger, Stefan; Yousry, Indra; Brueckmann, Hartmut; Schmid-Elsaesser, Robert; Tonn, Joerg-Christian

    2006-02-01

    The indications for resection of cavernous malformations (CMs) of the brainstem include neurological deficits, (recurrent) hemorrhage, and surgically accessible location. In particular, knowledge of the thickness of the parenchymal layer and of the CM's spatial relation to nuclei, tracts, cranial nerves, and vessels is critical for planning the surgical approach. We reviewed the operative treatment of 13 patients with 14 brainstem CMs, with special regard to refined three-dimensional (3D)-constructive interference in steady-state (CISS) magnetic resonance imaging (MRI). Patients were evaluated neurologically and by conventional spin-echo/fast spin-echo and 3D-CISS MRI. Surgery was performed with the use of microsurgical techniques and neurophysiological monitoring. Eleven CMs were located in the pons/pontomedullary region; 10 of the 11 were operated on via the lateral suboccipital approach. Three CMs were located near the floor of the fourth ventricle and operated on via the median suboccipital approach, with total removal of all CMs. Results were excellent or good in 10 patients; one patient transiently required tracheostomy, and two patients developed new hemipareses/ataxia with subsequent improvement. Not only did 3D-CISS sequences allow improved judgment of the thickness of the parenchymal layer over the lesion compared with spin-echo/fast spin-echo MRI, but 3D-CISS imaging also proved particularly superior in demonstrating the spatial relation of the lesion to fairly "safe" entry zones (e.g., between the trigeminal nerve and the VIIth and VIIIth nerve groups) by displaying the cranial nerves and vessels within the cerebellopontine cistern more precisely. Surgical treatment of brainstem CMs is recommended in symptomatic patients. Especially in patients with lesions situated ventrolaterally, the 3D-CISS sequence seems to be a valuable method for identifying the CM's relation to safe entry zones, thereby facilitating the surgical approach.

  6. Detailed imaging of the normal anatomy and pathologic conditions of the cavernous region at 3 Tesla using a contrast-enhanced MR angiography

    Energy Technology Data Exchange (ETDEWEB)

    Linn, Jennifer; Peters, Friederike; Lummel, Nina; Brueckmann, Hartmut; Yousry, Indra [University Hospital Munich, Department of Neuroradiology, Munich (Germany); Schankin, Christoph [University Hospital Munich, Department of Neurology, Munich (Germany); Rachinger, Walter [University Hospital Munich, Department of Neurosurgery, Munich (Germany)

    2011-12-15

    The purpose of this study was to evaluate the potential of a high-resolution contrast-enhanced magnetic resonance angiography (CE-MRA) at 3 Tesla for the delineation of the cavernous sinus (CS) anatomy both under normal and under pathological conditions. Fifteen patients without pathologies in the CS and ten patients with pituitary adenomas were included. The CE-MRA was performed on a 3-Tesla scanner and analyzed collaboratively by two readers. The cranial nerves (CNs) within the CS, namely CNIII, CNIV, CNV1, CNV2, and CNVI, were identified in both patient groups. In the adenoma patients it was also assessed whether and to which extend the adenoma invaded the CS and the spatial relationship between tumor and CNs was determined. In the patients with normal CS anatomy, CNIII could be identified in 100%, CNIV in 86.7%, and CNV1, CNV2, as well as CNVI in 100% of analyzed sides. Pituitary adenomas invaded the CS unilaterally (right side) in four patients, and bilaterally in six patients. In patients with adenomas, the CN could be identified and differentiated from the tumor in the following percentages: CNIII in 100%, CNIV in 70%, both CNV1 and CNV2 in 90%, and CNVI in 100%. In all these cases, the tumor-nerve spatial relationship could be visualized. 3-Tesla CE-MRA allows detailed imaging of the complex anatomy of the CS and its structures. In adenoma patients, it clearly visualizes the spatial relationship between tumor and CNs, and thus might be helpful to optimize presurgical planning. (orig.)

  7. 10th February 2011-Ambassador Permanent Representative of the Republic of Ecuador to the United Nations H.E. Mr Mauricio Montalvo visiting CMS cavern with Head of International Relations F. Pauss

    CERN Document Server

    Maximilien Brice

    2011-01-01

    Photo 1,9-50:the delegation visiting the CMS cavern Photo 2-8:visiting CMS Control room Photo 51:V. Aguilar,First Secretary-G. Tonelli,CMS Collaboration Spokesperson-M. Montalvo-L. Sulak,CMS Collaboration-M. del Carmen Vivar,Third Secretary-N. Mora,Personal Assistant of Ambassador-B. Jones,Information Technology Department, EU Projects-L. Vayas,Counsellor-F. Pauss-J. Carlos Sánchez,First Secretary-J. Salicio,Adviser for Ecuador Photo 52-59:M.Montalvo signing the Guest Book with F. Pauss

  8. Successful treatment of direct carotid-cavernous fistula in a patient with Ehlers-Danlos syndrome type IV without arterial puncture: the transvenous triple-overlay embolization (TAILOREd) technique.

    Science.gov (United States)

    Huynh, Thien J; Morton, Ryan P; Levitt, Michael R; Ghodke, Basavaraj V; Wink, Onno; Hallam, Danial K

    2017-08-18

    We report successful transvenous treatment of direct carotid-cavernous fistula in a patient with Ehlers-Danlos syndrome type IV using a novel triple-overlay embolization (TAILOREd) technique without the need for arterial puncture, which is known to be highly risky in this patient group. The TAILOREd technique allowed for successful treatment using preoperative MR angiography as a three-dimensional overlay roadmap combined with cone beam CT and live fluoroscopy, precluding the need for an arterial puncture. 2017 BMJ Publishing Group Ltd.

  9. Intra-arterial embolization with pingyangmycin-lipiodol emulsion for the treatment of hepatic cavernous hemangioma: an analysis of factors affecting therapeutic results

    International Nuclear Information System (INIS)

    Zeng Qingle; Chen Yong; Zhao Jianbo; Zhang Kewei; Li Yanhao

    2009-01-01

    Objective: To analyze the factors that might affect the therapeutic results of pingyangmycin-lipiodol emulsion intra-arterial sclerosing embolization (PLE-IASE) in treating symptomatic cavernous hemangioma of liver (SCHL). Methods: PLE-IASE was performed in 89 patients with SCHL (32 males and 57 females). Before treatment the mean diameter of the hemangioma was (8.3±3.8) cm. Of 89 patients, 53 experienced anxiety, 35 suffered from right upper abdominal pain and the remaining one developed Kasabach-Merrit syndrome. Before PLE-IASE, the arteriographic classification was conducted based on hepatic arteriographic findings. Then pingyangmycin-lipiodol emulsion (PLE) was injected through the feeding artery. The dosage of pingyangmycin (PYM) was (9.8 ± 4.4) mg and the dosage of lipiodol (LP) was (5.9 ± 2.9) ml. The lipiodol deposition status was judged by the follow-up spot film taken immediately after PLE-IASE. The observations of the occurrence of complications, the relief of symptoms and the minification of SCHL were followed for 6-72 months after PLE-IASE. The linear regression analysis statistics was conducted by taking the minification as dependent variable and taking the arteriographic classification, lipiodol deposition status, the dosage of PYM, the dosage of lipiodol and the preoperative SCHL diameter as independent variable. Results: Of all 89 cases of SCHL, hypervascular type was seen in 51, hypovascular type in 26 and arteriovenous shunt (AVS) type in 12. Good lipiodol deposition status was found in 64 patients and poor deposition in 25 patients after PLE-IASE. After PLE-IASE, the symptom of anxiety in 53 patients was relieved and the right upper abdominal pain was reduced in 33 cases although intermittent pain still remained in 2 patients. The blood platelet count of the patient with Kasabach-Merrit syndrome returned to normal after the treatment. The symptomatic relieve rate was 98.7%. No serious complications occurred in the follow-up period. The linear

  10. Superiority of constructive interference in steady-state MRI sequencing over T1-weighted MRI sequencing for evaluating cavernous sinus invasion by pituitary macroadenomas.

    Science.gov (United States)

    Lang, Min; Silva, Danilo; Dai, Lu; Kshettry, Varun R; Woodard, Troy D; Sindwani, Raj; Recinos, Pablo F

    2018-03-23

    OBJECTIVE Preoperatively determining the extent of parasellar invasion of pituitary macroadenomas is useful for surgical planning and patient counseling. Here, the authors compared constructive interference in steady state (CISS), a T2-weighted gradient-echo MRI sequence, to volume-interpolated breath-hold examination (VIBE), a T1-weighted gradient-echo MRI sequence, for evaluation of cavernous sinus invasion (CSI) by pituitary macroadenomas. METHODS VIBE and CISS images of 98 patients with pituitary macroadenoma were retrospectively analyzed and graded using the modified Knosp classification. The Knosp grades were correlated to surgical findings of CSI, which were determined intraoperatively using 0° and 30° endoscopes. The predictive accuracies for CSI according to the Knosp grades derived from the CISS and VIBE images were compared using receiver operating characteristic (ROC) curves. Postoperative MRI was used to evaluate the gross-total resection (GTR) rates. RESULTS The CSI rate by pituitary macroadenomas was 27.6% (27 of 98 cases). Of 196 assessments (left and right sides of 98 macroadenomas), 45 (23.0%) had different Knosp grades when scored using VIBE versus CISS images. For the VIBE images, 0% of Knosp grade 0, 4.5% of grade 1, 23.8% of grade 2, 42.1% of grade 3A, 100% of grade 3B, and 83.3% of grade 4 macroadenomas were found to have CSI intraoperatively. For the CISS images, 0% of Knosp grade 0, 2.1% of grade 1, 31.3% of grade 2, 56.3% of grade 3A, 100% of grade 3B, and 100% of grade 4 macroadenomas were found to have CSI intraoperatively. Two pituitary macroadenomas were classified as grade 4 on VIBE sequences but grades 3A and 2 on CISS sequences; CSI was not observed intraoperatively in both cases. The GTR rate was 64.3% and 60.0% for high-grade (3A, 3B, and 4) macroadenomas classified using VIBE and CISS sequences, respectively. The areas under the ROC curves were 0.94 and 0.97 for VIBE- and CISS-derived Knosp grades (p = 0.007), respectively

  11. 1 October 2013 - British Minister of State for Trade and Investment Lord Green of Hurstpierpoint signing the guest book with Head of Internationals Relations R. Voss; visiting the LHC tunnel at Point 1 and the ATLAS experimental cavern with ATLAS Collaboration Members K. Behr and J. Catmore.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    1 October 2013 - British Minister of State for Trade and Investment Lord Green of Hurstpierpoint signing the guest book with Head of Internationals Relations R. Voss; visiting the LHC tunnel at Point 1 and the ATLAS experimental cavern with ATLAS Collaboration Members K. Behr and J. Catmore.

  12. 23 July - Italian Director-General for Prevention G. Ruocco and Director-General for European and International Relations Ministry of Health D. Roderigo visiting the ATLAS experimental cavern with ATLAS Deputy Spokesperson B. Heinemann. Life Sciences Section M. Cirilli and Life Sciences Adviser M. Dosanjh present.

    CERN Document Server

    Anna Pantelia

    2013-01-01

    23 July - Italian Director-General for Prevention G. Ruocco and Director-General for European and International Relations Ministry of Health D. Roderigo visiting the ATLAS experimental cavern with ATLAS Deputy Spokesperson B. Heinemann. Life Sciences Section M. Cirilli and Life Sciences Adviser M. Dosanjh present.

  13. 21 May 2013 - Slovakian State Secretary, Ministry of Health V. Čislák signing the Guest Book with CERN Director-General R. Heuer; in the LHC tunnel at Point 2 with V. Senaj (Technology Department); in the ALICE experimental cavern with P. Chochula (Physics Department). M. Cirilli (Knowledge Transfer Group) present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    21 May 2013 - Slovakian State Secretary, Ministry of Health V. Čislák signing the Guest Book with CERN Director-General R. Heuer; in the LHC tunnel at Point 2 with V. Senaj (Technology Department); in the ALICE experimental cavern with P. Chochula (Physics Department). M. Cirilli (Knowledge Transfer Group) present.

  14. Senior Senator from Florida and Chairman, Senate Committee on Space, Aeronautics and Related Sciences W. Nelson, visiting the ATLAS cavern and LHC tunnel with ATLAS Collaboration Spokesperson P. Jenni and AMS Collaboration Spokesperson S.C.C.Ting, 16 March 2008.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    Senior Senator from Florida and Chairman, Senate Committee on Space, Aeronautics and Related Sciences W. Nelson, visiting the ATLAS cavern and LHC tunnel with ATLAS Collaboration Spokesperson P. Jenni and AMS Collaboration Spokesperson S.C.C.Ting, 16 March 2008.

  15. 9 April 2013 - Minister for Universities and Science United Kingdom of Great Britain and Northern Ireland D. Willetts in the ATLAS experimental cavern with ATLAS Collaboration Spokesperson D. Charlton and in the LHC tunnel at Point 1 with Beams Department Head P. Collier. Director for Accelerators and Technology S. Myers, Editor at the Communication Group K. Kahle and Beams Department Engineer R. Veness present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    9 April 2013 - Minister for Universities and Science United Kingdom of Great Britain and Northern Ireland D. Willetts in the ATLAS experimental cavern with ATLAS Collaboration Spokesperson D. Charlton and in the LHC tunnel at Point 1 with Beams Department Head P. Collier. Director for Accelerators and Technology S. Myers, Editor at the Communication Group K. Kahle and Beams Department Engineer R. Veness present.

  16. 17 October 2013 - C. Ashton High Representative of the European Union for Foreign Affairs and Security Policy, Vice-President of the European Commission visiting the ATLAS cavern with ATLAS Collaboration Spokesperson D. Charlton; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest book with CERN Director-General R. Heuer.

    CERN Multimedia

    Maximilien Brice

    2013-01-01

    17 October 2013 - C. Ashton High Representative of the European Union for Foreign Affairs and Security Policy, Vice-President of the European Commission visiting the ATLAS cavern with ATLAS Collaboration Spokesperson D. Charlton; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest book with CERN Director-General R. Heuer.

  17. 25 April 2012 - Latvia Riga Technical University Rector L. Ribickis signing the guest book with CERN Director-General R. Heuer and visiting the LHC tunnel at Point 5 and CMS experimental cavern with Deputy Spokesperson T. Camporesi and Adviser for the Republic of Latvia T. Kurtyka.

    CERN Document Server

    Maximilien Brice

    2012-01-01

    25 April 2012 - Latvia Riga Technical University Rector L. Ribickis signing the guest book with CERN Director-General R. Heuer and visiting the LHC tunnel at Point 5 and CMS experimental cavern with Deputy Spokesperson T. Camporesi and Adviser for the Republic of Latvia T. Kurtyka.

  18. 12 December 2013 - Sir Konstantin Novoselov, Nobel Prize in Physics 2010, signing the guest book with International Relations Adviser E. Tsesmelis; visiting the ATLAS experimental cavern with Spokesperson D. Charlton; in the LHC tunnel with Technology Department Head F. Bordry. I. Antoniadis, CERN Theory Group Leader, accompanies throughout.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    12 December 2013 - Sir Konstantin Novoselov, Nobel Prize in Physics 2010, signing the guest book with International Relations Adviser E. Tsesmelis; visiting the ATLAS experimental cavern with Spokesperson D. Charlton; in the LHC tunnel with Technology Department Head F. Bordry. I. Antoniadis, CERN Theory Group Leader, accompanies throughout.

  19. 3 February 2011 - British Members of the Science and Technology Committee (Commons)led by A. Miller MP signing the guest book with CERN Director for Accelerators and Technology S. Myers; in the ATLAS experimental cavern at LHC Point 1 with Spokesperson F. Gianotti and Deputy D. Charlton.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    3 February 2011 - British Members of the Science and Technology Committee (Commons)led by A. Miller MP signing the guest book with CERN Director for Accelerators and Technology S. Myers; in the ATLAS experimental cavern at LHC Point 1 with Spokesperson F. Gianotti and Deputy D. Charlton.

  20. 6 November 2013 - Permanent Representative of Chile to the United Nations Office and Other international organizations in Geneva Ambassador J. Balmaceda Serigos signing the guest book with Adviser for Latin America J. Salicio Diez; visiting the ATLAS experimental cavern with Spokesperson D. Charlton (Spouse, Son and First Secretary present).

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    6 November 2013 - Permanent Representative of Chile to the United Nations Office and Other international organizations in Geneva Ambassador J. Balmaceda Serigos signing the guest book with Adviser for Latin America J. Salicio Diez; visiting the ATLAS experimental cavern with Spokesperson D. Charlton (Spouse, Son and First Secretary present).

  1. 28 March 2014 - Italian Minister of Education, University and Research S. Giannini welcomed by CERN Director-General R. Heuer and Director for Research and Scientific Computing S. Bertolucci in the ATLAS experimental cavern with Former Collaboration Spokesperson F. Gianotti. Signature of the guest book with Belgian State Secretary for the Scientific Policy P. Courard.

    CERN Multimedia

    Gadmer, Jean-Claude

    2014-01-01

    28 March 2014 - Italian Minister of Education, University and Research S. Giannini welcomed by CERN Director-General R. Heuer and Director for Research and Scientific Computing S. Bertolucci in the ATLAS experimental cavern with Former Collaboration Spokesperson F. Gianotti. Signature of the guest book with Belgian State Secretary for the Scientific Policy P. Courard.

  2. 17th April 2008 - W. W. Tichenor, Ambassador, Permanent Representative of the United States of America to the United Nations Office and other international organisations in Geneva visiting the ATLAS cavern with Collaboration Spokesperson P. Jenni and AMS Collaboration Spokesperson S.C.C.Ting.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    17th April 2008 - W. W. Tichenor, Ambassador, Permanent Representative of the United States of America to the United Nations Office and other international organisations in Geneva visiting the ATLAS cavern with Collaboration Spokesperson P. Jenni and AMS Collaboration Spokesperson S.C.C.Ting.

  3. 8 May 2013 - Swedish European Spallation Source Chief Executive Officer J. H. Yeck in the ATLAS visitor centre and experimental cavern with Collaboration Spokesperson D. Charlton (also present M. Nessi, R. Garoby and E. Tsesmelis); signing the guest book with International Relations Adviser E. Tsesmelis.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    8 May 2013 - Swedish European Spallation Source Chief Executive Officer J. H. Yeck in the ATLAS visitor centre and experimental cavern with Collaboration Spokesperson D. Charlton (also present M. Nessi, R. Garoby and E. Tsesmelis); signing the guest book with International Relations Adviser E. Tsesmelis.

  4. 16 December 2013 - Hooke Professor of Experimental Physics and Pro Vice Chancellor University of Oxford Prof. I. Walmsley visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, Physics Department, ATLAS Collaboration P. Wells and Chair, CMS Collaboration Board, Oxford University and Purdue University I. Shipsey

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    16 December 2013 - Hooke Professor of Experimental Physics and Pro Vice Chancellor University of Oxford Prof. I. Walmsley visiting the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, Physics Department, ATLAS Collaboration P. Wells and Chair, CMS Collaboration Board, Oxford University and Purdue University I. Shipsey

  5. 19 July 2013 - Chairman of the Policy Committee, European Cancer Organisation, President, European Association for Cancer Research E. Celis visiting the ATLAS experimental cavern with ATLAS Collaboration Deputy Spokesperson, B. Heinemann and signing the Guest Book with Director for Accelerators and Technology S. Myers. Life Sciences Adviser M. Dosanjh present.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    19 July 2013 - Chairman of the Policy Committee, European Cancer Organisation, President, European Association for Cancer Research E. Celis visiting the ATLAS experimental cavern with ATLAS Collaboration Deputy Spokesperson, B. Heinemann and signing the Guest Book with Director for Accelerators and Technology S. Myers. Life Sciences Adviser M. Dosanjh present.

  6. 22. August 2013 - Permanent Representative of the Republic of Korea to the United Nations Office and other international organizations in Geneva, Ambassador Extraordinary and Plenipotentiary S. Choi signing the guest book with Director-General R. Heuer; visiting the LHC tunnel with P. Fessia and the CMS experimental cavern with Former Collaboration Spokesperson J. Virdee.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    22. August 2013 - Permanent Representative of the Republic of Korea to the United Nations Office and other international organizations in Geneva, Ambassador Extraordinary and Plenipotentiary S. Choi signing the guest book with Director-General R. Heuer; visiting the LHC tunnel with P. Fessia and the CMS experimental cavern with Former Collaboration Spokesperson J. Virdee.

  7. 17 September 2013 - Estonian Minister of Education and Research J. Aaviksoo signing the guest book with CERN Director-General R- Heuer; visiting the TOTEM facility with TOTEM Collaboration Spokesperson S. Giani; in the LHC tunnel at Point 5 with International Relations Adviser T. Kurtyka and visiting the CMS cavern with CMS Collaboration Spokesperson J. Incandela. International Relations Adviser R. Voss present.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    17 September 2013 - Estonian Minister of Education and Research J. Aaviksoo signing the guest book with CERN Director-General R- Heuer; visiting the TOTEM facility with TOTEM Collaboration Spokesperson S. Giani; in the LHC tunnel at Point 5 with International Relations Adviser T. Kurtyka and visiting the CMS cavern with CMS Collaboration Spokesperson J. Incandela. International Relations Adviser R. Voss present.

  8. 1er février 2011-Première Présidente de la Confédération Suisse (1999)-Mme Ruth Dreifuss-Visite de la caverne expérimentale d’ATLAS avec F. Pauss, Chef des Relations internationales

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Photo 1-24:Collaboration ATLAS, Ancien Porte-parole P. Jenni+F. Pauss+Experte en pédagogie S. Forster+R. Dreifuss+C. Bossy+JP Bossy, visite de la caverne ATLAS Photo 25-40:Visite du Tunnel LHC au Point 1

  9. 18 February 2013 - Foundation for Polish Science President M. Zylicz signing the guest book with CERN Director for Research and Scientific Computing S. Bertolucci; visiting the ALICE experimental cavern with K. Safarik and L. Graczykowskind LHC tunnel with Technology Department A. Siemko.

    CERN Multimedia

    Samuel Morier-Genoud

    2013-01-01

    18 February 2013 - Foundation for Polish Science President M. Zylicz signing the guest book with CERN Director for Research and Scientific Computing S. Bertolucci; visiting the ALICE experimental cavern with K. Safarik and L. Graczykowskind LHC tunnel with Technology Department A. Siemko.

  10. 21 January 2008 - Vice-President of the Human Rights Commission Z. Muhsin Al Hussein, Ambassador to United Nations A. Attar and their delegation from Saudi Arabia, visiting the ATLAS experimental cavern with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

    CERN Multimedia

    Claudia Marcelloni

    2008-01-01

    21 January 2008 - Vice-President of the Human Rights Commission Z. Muhsin Al Hussein, Ambassador to United Nations A. Attar and their delegation from Saudi Arabia, visiting the ATLAS experimental cavern with Collaboration Spokesperson P. Jenni and Technical Coordinator M. Nessi.

  11. Mr Lars Leijonborg, Minister for Higher Education and Research of Sweden visiting the cavern ATLAS, the control room of ATLAS and the machine LHC at Point 1 with Collaboration Spokesperson P. Jenni and Dr. Jos Engelen, Chief Scientific Officer of CERN.

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    Mr Lars Leijonborg, Minister for Higher Education and Research of Sweden visiting the cavern ATLAS, the control room of ATLAS and the machine LHC at Point 1 with Collaboration Spokesperson P. Jenni and Dr. Jos Engelen, Chief Scientific Officer of CERN.

  12. 29 November 2013 - U. Humphrey Orjiako Nigerian Ambassador Extraordinary and Plenipotentiary Permanent Mission to the United Nations Office and other international organisations in Geneva signing the Guest Book with Head of International Relations R. Voss, visiting the LHC tunnel at Point 2 and the ALICE cavern with ALICE Collaboration Deputy Spokesperson Y. Schutz.

    CERN Multimedia

    Noemi Caraban

    2013-01-01

    29 November 2013 - U. Humphrey Orjiako Nigerian Ambassador Extraordinary and Plenipotentiary Permanent Mission to the United Nations Office and other international organisations in Geneva signing the Guest Book with Head of International Relations R. Voss, visiting the LHC tunnel at Point 2 and the ALICE cavern with ALICE Collaboration Deputy Spokesperson Y. Schutz.

  13. 5 June 2013 - European Union Ambassador to Switzerland and the Principality of Liechtenstein R. Jones in the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, in the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the guest book with Director-General R. Heuer. Head of the EU Projects Office S. Stavrev present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    5 June 2013 - European Union Ambassador to Switzerland and the Principality of Liechtenstein R. Jones in the ATLAS cavern with ATLAS Collaboration Deputy Spokesperson T. Wengler, in the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the guest book with Director-General R. Heuer. Head of the EU Projects Office S. Stavrev present.

  14. 16 December 2013 - P. Lavie President of the Technion Institute of Technology in Israel visiting the ATLAS cavern with ATLAS Deputy Spokesperson T. Wengler; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest Book with CERN Director-General R. Heuer. G. Mikenberg, E. Rabinovici, Y. Rozen and S. Tarem present throughout.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    16 December 2013 - P. Lavie President of the Technion Institute of Technology in Israel visiting the ATLAS cavern with ATLAS Deputy Spokesperson T. Wengler; visiting the LHC tunnel at Point 1 with Technology Department Head F. Bordry and signing the Guest Book with CERN Director-General R. Heuer. G. Mikenberg, E. Rabinovici, Y. Rozen and S. Tarem present throughout.

  15. 13 September 2013 - Chairman of the Board of Directors of the von Karman Institute Kingdom of Belgium J.-P. Contzen visiting the ATLAS experimental cavern with ATLAS Former Spokesperson P. Jenni; visiting the LHC tunnel at Point 1 with Technology Department N. Delruelle and signing the guest book with Technology Department Head F. Bordry. International Relations Adviser T. Kurtyka present.

    CERN Multimedia

    Laurent Egli (visit)

    2013-01-01

    13 September 2013 - Chairman of the Board of Directors of the von Karman Institute Kingdom of Belgium J.-P. Contzen visiting the ATLAS experimental cavern with ATLAS Former Spokesperson P. Jenni; visiting the LHC tunnel at Point 1 with Technology Department N. Delruelle and signing the guest book with Technology Department Head F. Bordry. International Relations Adviser T. Kurtyka present.

  16. 19 September 2011 - Austrian State Secretary for European and International Affairs W. Waldner, signing the guest book with Head of International Relations F. Pauss; visiting CMS service cavern with Collaboration Spokesperson G. Tonelli and the LHC superconducting magnet test hall with M. Zerlauth.

    CERN Multimedia

    Benoît Jeannet

    2011-01-01

    Austrian state secretary for foreign affairs, Wolfgang Waldner, left, was welcomed to CERN by Felicitas Pauss, head of international relations at CERN, on 19 September. While at CERN, he toured the CMS control room and underground experimental service cavern, the LHC superconducting magnet test hall, and the Universe of Particles exhibition in the Globe of Science and Innovation.

  17. Tuesday 28 January 2014 - K. E. Huthmacher Ministerialdirektor Provision for the Future - Basic and Sustainability Research Federal Ministry of Education and Research (BMBF) visiting the stands with R. Heuer CERN Director-General on the occasion of the Inauguration of the Industrial Exhibition Germany@CERN and visiting the ATLAS Cavern with D. Charlton ATLAS Collaboration Spokesperson and R. Voss Head of International Relations.

    CERN Multimedia

    Pantelia, Anna

    2014-01-01

    Tuesday 28 January - K. E. Huthmacher Ministerialdirektor Provision for the Future - Basic and Sustainability Research Federal Ministry of Education and Research (BMBF) visiting the stands with R. Heuer CERN Director-General on the occasion of the Inauguration of the Industrial Exhibition Germany@CERN and visiting the ATLAS Cavern with D. Charlton ATLAS Collaboration Spokesperson and R. Voss Head of International Relations.

  18. 5 June 2013 - Sri Lankan Senior Minister of Scientific Affairs T. Vitharana signing the guest book with Director-General R. Heuer, in the LHC tunnel at Point 5 with International Relations Adviser R. Voss and in the CMS cavern with CERN Team leader A. Petrilli.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    5 June 2013 - Sri Lankan Senior Minister of Scientific Affairs T. Vitharana signing the guest book with Director-General R. Heuer, in the LHC tunnel at Point 5 with International Relations Adviser R. Voss and in the CMS cavern with CERN Team leader A. Petrilli.

  19. 16 July 2013 - Israel Ministry of Education Director-General D. Stauber in the LHC tunnel at Point 1 with L. Tavian, visiting the ATLAS experimental cavern with Senior Physicist G. Mikenberg; Israeli Delegate to CERN Council E. Rabinovici and CERN Adviser for Israel E. Tsesmelis present; signing the guest book with CERN Director-General R. Heuer.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    16 July 2013 - Israel Ministry of Education Director-General D. Stauber in the LHC tunnel at Point 1 with L. Tavian, visiting the ATLAS experimental cavern with Senior Physicist G. Mikenberg; Israeli Delegate to CERN Council E. Rabinovici and CERN Adviser for Israel E. Tsesmelis present; signing the guest book with CERN Director-General R. Heuer.

  20. 24 May 2013 - Rector of the Polish Stanislaw Staszic AGH University of Science and Technology T. Slomka in the LHC tunnel at Point 8 with Senior Polish Staff Member A. Siemko, in LHCb experimental cavern with LHCb Collaboration Spokesperson P. Campana and signing the guest book with Director-General R. Heuer. Adviser for Eastern Europe T. Kurtyka present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    24 May 2013 - Rector of the Polish Stanislaw Staszic AGH University of Science and Technology T. Slomka in the LHC tunnel at Point 8 with Senior Polish Staff Member A. Siemko, in LHCb experimental cavern with LHCb Collaboration Spokesperson P. Campana and signing the guest book with Director-General R. Heuer. Adviser for Eastern Europe T. Kurtyka present.

  1. 30 August 2013 - Senior Vice Minister for Foreign Affairs in Japan M. Matsuyama signing the guest book with CERN Director-General; visit the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton and visiting the LHC tunnel at Point 1 with former ATLAS Japan national contact physicist T. Kondo. R. Voss and K. Yoshida present throughout.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    30 August 2013 - Senior Vice Minister for Foreign Affairs in Japan M. Matsuyama signing the guest book with CERN Director-General; visit the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton and visiting the LHC tunnel at Point 1 with former ATLAS Japan national contact physicist T. Kondo. R. Voss and K. Yoshida present throughout.

  2. 8 April 2013 - Indian Hon'ble Minister for Ministry of Science & Technology and Ministry of Earth Sciences Shri Sudini Jaipal Reddy in the LHC tunnel with K. Foraz, visiting the CMS cavern with Technical Coordinator A. Ball and Former Spokesperson T. Virdee, signing the guest book with Director-General R. Heuer.

    CERN Multimedia

    Samuel Morier-Genoud

    2013-01-01

    8 April 2013 - Indian Hon'ble Minister for Ministry of Science & Technology and Ministry of Earth Sciences Shri Sudini Jaipal Reddy in the LHC tunnel with K. Foraz, visiting the CMS cavern with Technical Coordinator A. Ball and Former Spokesperson T. Virdee, signing the guest book with Director-General R. Heuer.

  3. SU-E-T-304: Dosimetric Comparison of Cavernous Sinus Tumors: Heterogeneity Corrected Pencil Beam (PB-Hete) Vs. X-Ray Voxel Monte Carlo (XVMC) Algorithms for Stereotactic Radiotherapy (SRT)

    Energy Technology Data Exchange (ETDEWEB)

    Pokhrel, D; Sood, S; Badkul, R; Jiang, H; Saleh, H; Wang, F [University of Kansas Hospital, Kansas City, KS (United States)

    2015-06-15

    Purpose: To compare dose distributions calculated using PB-hete vs. XVMC algorithms for SRT treatments of cavernous sinus tumors. Methods: Using PB-hete SRT, five patients with cavernous sinus tumors received the prescription dose of 25 Gy in 5 fractions for planning target volume PTV(V100%)=95%. Gross tumor volume (GTV) and organs at risk (OARs) were delineated on T1/T2 MRI-CT-fused images. PTV (range 2.1–84.3cc, mean=21.7cc) was generated using a 5mm uniform-margin around GTV. PB-hete SRT plans included a combination of non-coplanar conformal arcs/static beams delivered by Novalis-TX consisting of HD-MLCs and a 6MV-SRS(1000 MU/min) beam. Plans were re-optimized using XVMC algorithm with identical beam geometry and MLC positions. Comparison of plan specific PTV(V99%), maximal, mean, isocenter doses, and total monitor units(MUs) were evaluated. Maximal dose to OARs such as brainstem, optic-pathway, spinal cord, and lenses as well as normal tissue volume receiving 12Gy(V12) were compared between two algorithms. All analysis was performed using two-tailed paired t-tests of an upper-bound p-value of <0.05. Results: Using either algorithm, no dosimetrically significant differences in PTV coverage (PTVV99%,maximal, mean, isocenter doses) and total number of MUs were observed (all p-values >0.05, mean ratios within 2%). However, maximal doses to optic-chiasm and nerves were significantly under-predicted using PB-hete (p=0.04). Maximal brainstem, spinal cord, lens dose and V12 were all comparable between two algorithms, with exception of one patient with the largest PTV who exhibited 11% higher V12 with XVMC. Conclusion: Unlike lung tumors, XVMC and PB-hete treatment plans provided similar PTV coverage for cavernous sinus tumors. Majority of OARs doses were comparable between two algorithms, except for small structures such as optic chiasm/nerves which could potentially receive higher doses when using XVMC algorithm. Special attention may need to be paid on a case

  4. Cavernous hemangioma presenting marked hyperostosis

    International Nuclear Information System (INIS)

    Kobata, Hitoshi; Miyake, Hiroji; Kitamura, Junji; Kajikawa, Hiroshi; Ohta, Tomio

    1988-01-01

    The authors report here a case of hemangioma of the left parietal bone which presented headache and papilledema. This patient is a 37-year-old female who had, prior to admission, complained of increasing headache for one year and blurred vision for three months. She had no history of head injury. Local physical examinations revealed a slight bulging in her left parietal region which was insensitive to palpation and not adherent to the overlying scalp. Neurological examinations revealed bilateral papilledema and an incongruous bitemporal upper quadrant defect in the visual field. All the other neurological and laboratory data were normal. A plain skull roentogenogram showed a 9 x 9 cm osteolytic and characteristic honeycomb lesion in the parietal region. Systemic bone survey revealed a similar lesion in the right tibia which was not histologically examined. A marked accumulation of isotopes was detected on the bone scintigrams at both lesions. Selective external carotid angiograms demonstrated a tumor stain fed by the superficial temporal, occipital, and middle meningial arteries. CT scans of the brain and skull clearly showed a local thickening of and structural changes in the skull bone and also a mass effect on the brain and lateral ventricle. The lesioned bone was removed en bloc and replaced by an artificial bone. It was highly vascular, but not adherent to the overlying dura. The post-operative course was uneventful, and the headache and papilledema disappeared. Hemangioma of the skull presenting marked hyperostosis, as reported above, seems to be rare. In addition, in this case, skeletal angioma without any clinical manifestation was detected. Clinical and radiological pictures of the hemangioma of the skull and other bones were briefly discussed. (author)

  5. Cavernous Haemangioma -A Case Report

    Directory of Open Access Journals (Sweden)

    Sunil Kumar Sharma

    2016-07-01

    Full Text Available Hemangiomas are developmental vascular abnormalities and more than 50% of these lesions occur in the head and neck region, with the lips, tongue, buccal mucosa, and palate most commonly involved. They are considered as hamartomas rather than true neoplasms. Here we report a case of hemangioma of the tongue, discussing the diagnostic aspects and treatment modalities. Factors such as patient's age, size and site of lesion and the proximity of lesion to vital structure are paramount in the determination of the therapeutic approach and surgical excision. Even though radiotherapy, cryotherapy, laser therapy, medical treatment, injection of sclerosing substances and the selective embolization of the lingual artery seem to have some efficacy, the author conclude that surgery is the therapy of choice in the isolated vascular lesions of the tongue.

  6. gigapanorama of NA 62 cavern

    CERN Multimedia

    Brice, Maximilien

    2015-01-01

    The image shows the new rare Kaon decay experiment at CERN, called NA62. The NA62 experiment is 270 metres long and includes a 120-metre-long vacuum tank, shown here, housing several of the particle detectors. (Note: the experiment axis is a straight line, the curving of the tank is an optical effect of the photo.) Kaons are particles that decay into lighter elementary particles. The kaon decay processes are mostly well known, except for some very rare decay modes. For example, NA62 is investigating a rare decay predicted by the Standard Model in which a kaon decays into one pion and two neutrinos. This process occurs only once every 10 billion decays. The understanding of such ultra-rare decays are of great importance because they test the Standard Model in energy ranges not accessible by direct measurements. They are therefore complementary to the measurements at the LHC. ultra high definition on demand (photolab@cern.ch).

  7. Surgical outcome of motor deficits and neurological status in brainstem cavernous malformations based on preoperative diffusion tensor imaging: a prospective randomized clinical trial.

    Science.gov (United States)

    Li, Da; Jiao, Yu-Ming; Wang, Liang; Lin, Fu-Xin; Wu, Jun; Tong, Xian-Zeng; Wang, Shuo; Cao, Yong

    2018-03-16

    OBJECTIVE Surgical management of brainstem lesions is challenging due to the highly compact, eloquent anatomy of the brainstem. This study aimed to evaluate the safety and efficacy of preoperative diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) in brainstem cavernous malformations (CMs). METHODS A prospective randomized controlled clinical trial was performed by using stratified blocked randomization. The primary eligibility criterion of the study was being a surgical candidate for brainstem CMs (with informed consent). The study enrolled 23 patients who underwent preoperative DTI/DTT and 24 patients who did not (the control group). The pre- and postoperative muscle strength of both limbs and modified Rankin Scale (mRS) scores were evaluated. Muscle strength of any limb at 12 months after surgery at the clinic visit was the primary outcome; worsened muscle strength was considered to be a poor outcome. Outcome assessors were blinded to patient management. This study reports the preliminary results of the interim analysis. RESULTS The cohort included 47 patients (22 women) with a mean age of 35.7 years. The clinical baselines between these 2 groups were not significantly different. In the DTI/DTT group, the corticospinal tract was affected in 17 patients (73.9%): it was displaced, deformed/partially interrupted, or completely interrupted in 6, 7, and 4 patients, respectively. The surgical approach and brainstem entry point were adjusted in 3 patients (13.0%) based on DTI/DTT data. The surgical morbidity of the DTI/DTT group (7/23, 30.4%) was significantly lower than that of the control group (19/24, 79.2%, p = 0.001). At 12 months, the mean mRS score (1.1, p = 0.034) and percentage of patients with worsened motor deficits (4.3%, p = 0.006) were significantly lower in the DTI/DTT group than in the control group (1.7% and 37.5%). Multivariate logistic regression identified the absence of preoperative DTI/DTT (OR 0.06, 95% CI 0.01-0.73, p = 0

  8. 8th February 2011-Rector Universidad Autónoma de Sinaloa Mexico Dr Victor Antonio Corrales Burgeño-Mexico-visiting ALICE cavern and tunnel with ALICE Spokesperson P. Giubellino

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Photo 1,3-14:The delegation visiting ALICE cavern Photo 2:Dra. Beatriz E. Rodríguez Pérez\tDirectora del Centro de Políticas de Género para la igualdad entre Hombres y Mujeres,Dr Victor Antonio Corrales Burgeño,P. Giubellino Photo 15-29:The delegation visiting LHC Tunnel Photo 30-57:Signature of the Guest Book with CERN Director-General R. Heuer and Head of International Relations F. Pauss Photo 58:Adviser for Mexico J. Salicio,ALICE Collaboration Universidad Autonoma de Sinaloa I. Leon Monzon,ALICE Collaboration Centro Invest. Estudios Avanz. IPN (Cinnestav) G. Herrera Corral,R. Heuer,Dr Victor Antonio Corrales Burgeño,F. Pauss,Dra. Beatriz E. Rodríguez Pérez,Directora de Relaciones InternacionalesMC. América M. Lizárraga González

  9. High-flow bypass with radial artery graft followed by internal carotid artery ligation for large or giant aneurysms of cavernous or cervical portion: clinical results and cognitive performance.

    Science.gov (United States)

    Ono, Hideaki; Inoue, Tomohiro; Tanishima, Takeo; Tamura, Akira; Saito, Isamu; Saito, Nobuhito

    2018-04-01

    High-flow bypass followed by ligation of the internal carotid artery (ICA) is an effective treatment, but the impact of abrupt occlusion of the ICA is unpredictable, especially on postoperative cognitive function. The present study evaluated the clinical results as well as cognitive performances after high-flow bypass using radial artery graft (RAG) with supportive superficial temporal artery (STA)-middle cerebral artery (MCA) bypass, followed by ICA ligation. Ten consecutive patients underwent high-flow bypass surgery for large or giant ICA aneurysms of cavernous or cervical portion. Demographics, clinical information, magnetic resonance (MR) imaging, computed tomography, digital subtraction angiography (DSA), intraoperative somatosensory evoked potentials, neuropsychological examinations including the Wechsler Adult Intelligence Scale-Third Edition and the Wechsler Memory Scale-Revised (WMS-R), and follow-up data were analyzed. The aneurysm was located on the cavernous segment in eight cases and cervical segment in two cases, and mean aneurysm size was 27.9 mm. Postoperative DSA demonstrated robust bypass flow from the external carotid artery to MCA via the RAG, and no anterograde flow into the aneurysm. No patient showed new symptoms after the operation. Follow-up clinical study and MR imaging were performed in nine patients and showed no additional ischemic lesion compared with preoperative imaging. Seven patients completed neuropsychological examinations before and after surgery. All postoperative scores except WMS-R composite memory score slightly improved. High-flow bypass followed by ICA ligation can achieve good clinical outcomes. Successful high-flow bypass using RAG with supportive STA-MCA bypass and ICA ligation does not adversely affect postoperative cognitive function.

  10. Report on the explosion, fire, and oil spill resulting in one fatality and injury on September 21, 1978, at Well 6 of Cavern 6 at the West Hackberry, Louisiana, oil storage site of the strategic petroleum reserve. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    1978-11-01

    The following report is the independent product of the Accident Investigation Committee which was commissioned by the Department of Energy following the accident on September 21, 1978, at the Strategic Petroleum Reserve site at West Hackberry, Louisiana. This Committee is charged with the task of determining the nature, extent, and causes of that accident, which resulted in loss of life, injury and property damage, and the need for corrective action. A nonburning oil spill went into nearby Black Lake, but was contained by the deployment of a series of oil spill containment booms and a prevailing wind from the northeast that kept the oil spill in a restricted area near shore. Because of the rapid and effective containment and cleanup of the oil spill by the Rapid Response Team, it appears very likely at this time that Black Lake will not sustain any permanent environmental damage. Cavern 6 initially contained approximately 7,000,000 barrels of oil at a pressure of 650 psig measured at the well head. As of September 29, 1978, the Strategic Petroleum Reserve Office - New Orleans (SPRO) estimated that oil expulsion from Cavern 6 was 67,510 barrels. Of this, 34,620 barrels of oil are accounted for, including 31,200 barrels of oil released into Black Lake and subsequently recovered. The remainder (32,890 barrels) was assumed by SPRO to have been burned. The total loss is presently estimated by the Accident Investigation Committee 's consultant to be $12 million. An assessment of the technical problems present at the time of the accident is given. Recommendations for improved safety procedures are included.

  11. Spontaneous thrombosis of internal carotid artery: a natural history of giant carotid cavernous aneurysms Trombose espontânea da artéria carótida interna: a história natural dos aneurismas gigantes intracavernosos

    Directory of Open Access Journals (Sweden)

    Lucas Perez de Vasconcellos

    2009-06-01

    Full Text Available OBJECTIVE: To describe five cases of giant carotid cavernous aneurysms which evolved with spontaneous thrombosis of internal carotid artery (STICA, with emphasis at epidemiology, clinical presentation, natural history, related factors and neurological outcome. METHOD: There were 711 consecutives patients with 802 aneurysms with and without surgical treatment during a period of 19 years. We selected 35 patients with 40 carotid cavernous aneurysms (5% of which 20 (50% were giant aneurysms. Among those cases, 5 patients evolved with STICA (25%. Symptoms and findings at presentation were recorded and compared with those at outcome. RESULTS: Clinical presentation was commonly related to atherosclerotic factors such as elevated blood pressure (80%, diabetes mellitus (40% and dislipidemy (40%. All patients presented with hemicranial headache, ophthalmparesy and retro bulbar pain, and after STICA all presented improvement of symptoms. After STICA, 4 patients had regression of deficit, 2 partial and 2 complete. Four patients had sensorial trigeminal neuropathy in V1 and V2 territories, also showing improvement of symptoms after STICA. CONCLUSION: STICA is a common outcome in giant carotid cavernous aneurysms, and is related with significant improvement of symptoms; however, it may be catastrophic for those patients without efficient collateral circulation.OBJETIVO: Relatar cinco casos de aneurismas gigantes intracavernosos que evoluíram com trombose espontânea da artéria carótida interna (TEACI, estudando-se: prevalência, apresentação clínica, história natural, fatores associados e prognóstico neurológico. MÉTODO: Análise de 711 pacientes consecutivos com diagnóstico de 802 aneurismas cerebrais submetidos a tratamento clínico ou cirúrgico num período de 19 anos. Foram identificados 40 aneurismas intracavernosos, sendo que 20 desses eram gigantes. Dentre esses, 5 pacientes com aneurismas gigantes intracavernosos que evoluíram com TEACI

  12. Transposición de los cuerpos cavernosos para el tratamiento de la incontinencia urinaria posadenomectomía The cavernous bodies' transposition for treatment of post-adenomectomy urinary incontinence

    Directory of Open Access Journals (Sweden)

    Lourdes Santana Sarrhy

    2010-09-01

    Full Text Available Se documenta el caso de un paciente de 78 años de edad con antecedentes de haber sido operado de hiperplasia prostática benigna a través de una adenomectomía retropúbica y, después de retirada la sonda uretral, comenzó a tener salida involuntaria de orina en las posiciones de pie y sentado. Después de 6 meses los síntomas se mantuvieron e intensificaron, y múltiples estudios confirmaron una lesión iatrogénica del esfínter externo. Se realizó una transposición perineal de los cuerpos cavernosos y se creó una uretra funcional de aproximadamente 2,5 cm. Se observó mejoría clínica inmediata que inicialmente solucionó por completo la incontinencia urinaria posquirúrgica. A los 4 años de la operación, el paciente presenta solo escaso goteo posmiccional y ligera salida de orina con los grandes esfuerzos, que mejora con tratamiento médico.This is the case of a male patient aged 78 with a history of benign prostatic hyperplasia surgery through a retropubic adenomectomy and after the urethral stent withdrawal he had an involuntary urine output in standing and sitting down positions. After 6 months the symptoms remained and intensified and multiple studies confirmed an iatrogenic lesion of external sphincter. A perineal transposition of cavernous bodies and a approximately 2,5 cm functional urethra was created. There was an immediate clinical improvement that initially solved completely the postsurgical urinary incontinence. At four year after surgery, patient presents only a low postmicturition dripping and slight urine output with great efforts improving the medical treatment.

  13. Study on the planning of a demonstration plant for hydrogen fuel production by electrolysis using caching in salt caverns under pressure; Studie ueber die Planung einer Demonstrationsanlage zur Wasserstoff-Kraftstoffgewinnung durch Elektrolyse mit Zwischenspeicherung in Salzkavernen unter Druck

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-02-05

    In a two year research project the long-term storage of hydrogen as energy carrier has been assessed in detail for large renewable electricity quantities in underground storage caverns in Germany. Next to a regions analysis for potential storage sites, the benchmarking against other large scale storage concepts, a comparative and perspective analysis of alkaline and PEM-electrolysers also potential business cases for Power-to-Hydrogen in the mobility sector as well as for the chemical, electricity and natural gas industry have been analysed. [German] Durch den geplanten Ausbau der Stromerzeugung aus fluktuierenden, erneuerbaren Energien in Deutschland ruecken Speichertechnologien fuer elektrische Energie immer staerker in den Fokus des industriellen und politischen Interesses. Eine vielversprechende Moeglichkeit fuer eine Langzeitspeicherung bei hohen Anteilen von Wind- und Photovoltaikanlagen sind Speichertechnologien wie die Wasserstoffspeicherung mit Hilfe von Wasserelektrolyseuren. Diese koennen erneuerbaren Strom in grossen Mengen und bei entsprechender Steuerung selektiv in Zeiten mit hohem Dargebot z.B. an Windstrom chemisch speichern. Der gespeicherte Wasserstoff kann dann entweder zu einem spaeteren Zeitpunkt wieder rueckverstromt oder direkt stofflich verwertet werden, z.B. als Kraftstoff fuer den Verkehrssektor, als chemischer Rohstoff oder fuer den Hausenergiebereich durch Einspeisung in das Erdgastransportnetz. Thema der vorliegenden Studie sind Analysen und Planungen fuer die Erprobung des Gesamtsystems ''Wasserstoff-Elektrolyse-Speicherung'' in energiewirtschaftlich relevanten Dimensionen. Dazu werden mit einem neuen Ansatz techno-oekonomische Entwicklungspfade fuer Wasserstoff-Systeme unterschiedlicher Groesse und Technologien charakterisiert und technologische Risiken bei der Realisierung dieser Systeme identifiziert und bewertet. Diese Arbeiten werden ergaenzt durch Arbeiten auf dem Gebiet der Salzkavernenspeicherung in Form

  14. 28 November 2013 - N. N. Kudryavtsev, Russian Rector of the Moscow Institute of Physics and Technology signing an Agreement and the Guest Book with CERN Director-General R. Heuer; visiting the ATLAS cavern with ATLAS Deputy Spokesperson B. Heinemann and visiting the LHC tunnel at Point 1 with AGH University of Science and Technology A. Erokhin. M. Savino, Physics Department, Joint Institute for Nuclear Research also present.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    28 November 2013 - N. N. Kudryavtsev, Russian Rector of the Moscow Institute of Physics and Technology signing an Agreement and the Guest Book with CERN Director-General R. Heuer; visiting the ATLAS cavern with ATLAS Deputy Spokesperson B. Heinemann and visiting the LHC tunnel at Point 1 with AGH University of Science and Technology A. Erokhin. M. Savino, Physics Department, Joint Institute for Nuclear Research also present.

  15. 21 May 2013 - Greek Minister of Health A. Lykouretzos signing the guest book with CERN Director-General R. Heuer; visiting the LHC tunnel at POint 5 and CMS experimental cavern with Deputy Spokesperson T. Camporesi. CERN-HERMES Network Technical Coordinator E. Dimovasili; Life Sciences Adviser M. Dosanjh; National Contact Physicist, ATLAS Collaboration, NTU, Athens E. Gazis and International Relations Adviser R. Voss accompany the delegation throughout.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    21 May 2013 - Greek Minister of Health A. Lykouretzos signing the guest book with CERN Director-General R. Heuer; visiting the LHC tunnel at POint 5 and CMS experimental cavern with Deputy Spokesperson T. Camporesi. CERN-HERMES Network Technical Coordinator E. Dimovasili; Life Sciences Adviser M. Dosanjh; National Contact Physicist, ATLAS Collaboration, NTU, Athens E. Gazis and International Relations Adviser R. Voss accompany the delegation throughout.

  16. 8 October 2013 - Rolex Director- General G. Marini in the ATLAS Control Room with CERN Director-General R. Heuer and ATLAS Collaboration Senior Physicist C. Rembser; visiting the ATLAS experimental cavern at LHC Point 1. Were also present from the Directorate: S. Lettow, Director for Administration and General Infrastructure; from the ATLAS Collaboration: Technische Universitaet Dortmund (DE) J. Jentzsch and SLAC National Accelerator Laboratory (US) G. Piacquadio.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    8 October 2013 - Rolex Director- General G. Marini in the ATLAS Control Room with CERN Director-General R. Heuer and ATLAS Collaboration Senior Physicist C. Rembser; visiting the ATLAS experimental cavern at LHC Point 1. Were also present from the Directorate: S. Lettow, Director for Administration and General Infrastructure; from the ATLAS Collaboration: Technische Universitaet Dortmund (DE) J. Jentzsch and SLAC National Accelerator Laboratory (US) G. Piacquadio.

  17. M. G.-F. Leclerc, Préfet de la Haute-Savoie lors de sa visite dans le tunnel du LHC au Point 2 avec D. Delikaris, Département Technologie; dans la caverne de l'expérience ALICE avec B. Erazmus, Collaboration ALICE et lors de la signature du livre d'or avec F. Bordry, Chef du Département Technologie. P. Fassnacht, Conseiller au Bureau des Relations internationales présent.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    M. G.-F. Leclerc, Préfet de la Haute-Savoie lors de sa visite dans le tunnel du LHC au Point 2 avec D. Delikaris, Département Technologie; dans la caverne de l'expérience ALICE avec B. Erazmus, Collaboration ALICE et lors de la signature du livre d'or avec F. Bordry, Chef du Département Technologie. P. Fassnacht, Conseiller au Bureau des Relations internationales présent.

  18. Genetics Home Reference: cerebral cavernous malformation

    Science.gov (United States)

    ... malformations affect about 0.5 percent of the population worldwide. Related Information What information about a genetic condition can statistics provide? Why are some genetic conditions more common in particular ethnic groups? Genetic Changes Mutations in at least three genes, KRIT1 (also ...

  19. Interconnected cavernous structure of bacterial fruiting bodies.

    Directory of Open Access Journals (Sweden)

    Cameron W Harvey

    Full Text Available The formation of spore-filled fruiting bodies by myxobacteria is a fascinating case of multicellular self-organization by bacteria. The organization of Myxococcus xanthus into fruiting bodies has long been studied not only as an important example of collective motion of bacteria, but also as a simplified model for developmental morphogenesis. Sporulation within the nascent fruiting body requires signaling between moving cells in order that the rod-shaped self-propelled cells differentiate into spores at the appropriate time. Probing the three-dimensional structure of myxobacteria fruiting bodies has previously presented a challenge due to limitations of different imaging methods. A new technique using Infrared Optical Coherence Tomography (OCT revealed previously unknown details of the internal structure of M. xanthus fruiting bodies consisting of interconnected pockets of relative high and low spore density regions. To make sense of the experimentally observed structure, modeling and computer simulations were used to test a hypothesized mechanism that could produce high-density pockets of spores. The mechanism consists of self-propelled cells aligning with each other and signaling by end-to-end contact to coordinate the process of differentiation resulting in a pattern of clusters observed in the experiment. The integration of novel OCT experimental techniques with computational simulations can provide new insight into the mechanisms that can give rise to the pattern formation seen in other biological systems such as dictyostelids, social amoeba known to form multicellular aggregates observed as slugs under starvation conditions.

  20. A RARE CASE OF CAVERNOUS HAEMANGIOMA FACE

    Directory of Open Access Journals (Sweden)

    Tarun Guha

    2017-12-01

    Full Text Available PRESENTATION OF CASE A 60-year-old male presented to ENT OPD with a swelling on the left side of face for past 30 years. This was insidious in onset, slowly progressive, not associated with pain, visual disturbance, bleeding from the swelling, facial deformity or impairment of hearing. He had a small ulcer over the swelling for past 2 months and hunchback for past 20 years. He had no history of diabetes mellitus, hypertension, tuberculosis, bronchial asthma, radiation exposure, trauma, surgery in the past or any other intervention.

  1. Cavernous haemangioma mimicking as clitoral hypertrophy | Nayyar ...

    African Journals Online (AJOL)

    Haemangioma is the most common benign neoplasm of infantile age. It is most commonly located in head and neck region, trunk and extremities but very rarely it can be located at clitoris. However, it is very important to differentiate clitoral haemangioma from enlargement of the clitoris secondary to androgen excess.

  2. The behaviour of salt and salt caverns

    NARCIS (Netherlands)

    Fokker, P.A.

    1995-01-01

    Salts are mined for both storage and extraction purposes, either via dry or solution mining techniques. For operational, environmental and geological purposes, it is important to understand and predict the in situ behaviour of salt, in particular the creep and strength characteristics. A

  3. Complex carotid cavernous sinus fistulas Barrow type D: endovascular treatment via the ophthalmic vein, imaging control with standardized MRI, long-term results; Interdisziplinaere Embolisation spontaner Karotis-Cavernosus-Fisteln Typ D nach Barrow ueber die Vena ophthalmica: klinische Langzeitergebnisse und kernspintomografische Befunde

    Energy Technology Data Exchange (ETDEWEB)

    Struffert, T.; Grunwald, I.Q.; Reith, W. [Abteilung fuer Diagnostische und Interventionelle Neuroradiologie, Universitaetsklinikum des Saarlandes (Germany); Muecke, I. [Klinik fuer Augenheilkunde, Universitaetsklinikum des Saarlandes (Germany)

    2007-04-15

    Purpose: Since feeding arteries from both the internal and external carotid artery are common, cavernous fistulas of Barrow type D are difficult to treat. Embolization using the transarterial approach is considered to be the standard therapy. However, it is often impossible to embolize feeders from the internal carotid artery. The transorbital approach after anterior orbitotomy through the ophthalmic vein is an alternative in this complex situation. The following reports our experience with three female patients who underwent transvenous embolization. Procedural success was documented using standardized MRI and clinical reevaluation. Materials and Methods: Three female patients between 57 and 78 years of age were diagnosed with carotid cavernous fistulas by conventional angiogram. All patients were suffering from exophthalmus and visual impairment. Two patients showed secondary glaucoma and diplopia. In one patient we performed a technically successful transarterial embolization using particles, but no relevant improvement of the patient's condition was seen. Transfemoral transvenous access via the sinus petrosus was not possible in any patient. All patients were then embolized via the ophthalmic vein using GDC detachable coils. All patients were clinically reevaluated by an ophthalmologist. Also a standardized MRI was performed for documentation. Follow-up was performed for the first patient for 32 months, for the second patient for 34 months and for the third patient for 50 months. Results: Transvenous embolization was technically successful in all three cases. Clinical symptoms disappeared rapidly. Postprocedural MRI showed a symmetric diameter of the ophthalmic vein. Venous congestion of the orbit caused by fatty tissue edema regressed completely. Contrast-enhanced magnetic resonance angiography showed normal arterial vessels without evidence of fistula. (orig.)

  4. Feasibility of Noninvasive Diagnosis and Treatment Planning in a Case Series with Carotid-Cavernous Fistula using High-Resolution Time-Resolved MR-Angiography with Stochastic Trajectories (TWIST) and Extended Parallel Acquisition Technique (ePAT 6) at 3 T.

    Science.gov (United States)

    Seeger, A; Kramer, U; Bischof, F; Schuettauf, F; Ebner, F; Danz, S; Ernemann, U; Hauser, T-K

    2015-09-01

    The evaluation of carotid-cavernous fistulas (CCFs) and the intracranial vasculature has been predominantly carried out using conventional digital subtraction angiography (DSA). Recent developments in time-resolved magnetic resonance angiography (MRA) provide the opportunity to assess both multiple arterial and venous phases with high temporal and spatial resolution. Here, we investigated the feasibility of this technique to functionally assess CCF prior to intervention. Six consecutive patients with clinical symptoms of a CCF were scheduled for clinically indicated MRA and underwent a protocol that comprised conventional imaging sequences and high resolution time-resolved MRA with interleaved stochastic trajectories (TWIST). The location of the fistulous communication, the flow pattern, and venous drainage were determined by time-resolved MRA and compared with DSA which was available in five out of six patients. Typical morphological findings (including enlargement of the superior ophthalmic vein, exophthalmos) were found in all cases in both conventional MRI and time-resolved MRA source data. The temporal resolution of time-resolved MRA enabled a good separation of the early filling of the cavernous sinus during the arterial phase. Direct fistulous communication was assessed in three patients with good correlation to DSA, whereas indirect CCF could not definitely be visualized. The time-resolved MRA provided information about the flow pattern and the venous drainage of the fistula in all patients, which is essential for therapy planning. Time-resolved MRA provides important morphological and functional information in patients with CCF. Although DSA remains the gold standard for diagnosis and exact classification of fistulas, time-resolved MRA can provide the relevant hemodynamic information to plan interventional treatment as a one-step procedure with a focused diagnostic workup.

  5. Numerical analysis of the bearing capacity of complex rock mechanical underground systems with filigree structures in the presence of imponderables. A contribution to the systematization of the investigative process with application/demonstration using the example of the salt cavern ASSE II/south flank; Numerische Analyse des Tragverhaltens komplexer gebirgsmechanischer untertaegiger Systeme mit filigranen Strukturen bei Anwesenheit von Imponderabilien. Ein Beitrag zur Systematisierung des Untersuchungsprozesses mit Anwendung/Demonstration am Beispiel des Salzbergwerks Schacht ASSE II/Suedflanke

    Energy Technology Data Exchange (ETDEWEB)

    Dyogtyev, Oleksandr

    2017-03-02

    The thesis dealing with the numerical analysis of the bearing capacity of complex rock mechanical underground systems with filigree structures in the presence of imponderables covers the following issues: status of science and technology, concept for the performance of numerical studies on the bearing capacity of large-volume underground systems, application example salt cavern ASSE II - application of the developed concept/development of numerical tools for the overall system/application of the global model to the given questions/realization of the modification potential.

  6. Trombose séptica de seios cavernosos, transverso e sigmóide e de veia jugular, associada à meningite, secundária a furúnculo nasal: Relato de Caso Septic thrombosis of cavernous, transverse, sigmoid sinuses and jugular vein, associated with meningitis, secondary to nasal furuncle: Case report

    Directory of Open Access Journals (Sweden)

    Hélio Utida

    2002-06-01

    Full Text Available Os autores descrevem um caso de furúnculo nasal que evoluiu com trombose séptica de seio cavernoso, bilateral e assimétrica, e de seios transverso e sigmóide e de veia jugular interna a esquerda, associada à meningite bacteriana, em um paciente previamente hígido. Apesar da trombose séptica extensa de seios venosos, o paciente apresentou boa evolução, após tratamento clínico agressivo com antibióticos, corticosteróides e anticoagulantes. Porém, manteve como seqüela: paresia de VI nervo à esquerda e lesão parcial de nervo óptico homolateral.The authors report a case of nasal furuncle that progressed to septic bilateral and asymmetric thrombosis of cavernous, transverse, sigmoid sinus and internal jugular vein, associated with bacterial meningitis, in a previously healthy patient. In spite of the extensive thrombosis, the patient presented a good evolution, after an aggressive clinical treatment with antibiotics, corticosteroids and anticoagulants. However, there remained paresis of the VI nerve on the left and partial lesion of the homolateral optic nerve.

  7. 20 fevrier 2012 - Le Vice-Président du Gouvernement Wallon et Ministre du Développement durable et de la Fonction Publique en charge de l’Energie du Logement et de la Recherche J.-M. Nollet, Royaume de Belgique, visite la salle de contrôle de CMS au Point 5, la caverne expérimentale CMS et le hall de tests des aimants supraconducteurs du LHC. Les chefs de département T. Lagrange et F. Hemmer accompagnent la délégation. L. Walckiers guide la visite SM18.

    CERN Document Server

    Maximilien Brice

    2012-01-01

    20 fevrier 2012 - Le Vice-Président du Gouvernement Wallon et Ministre du Développement durable et de la Fonction Publique en charge de l’Energie du Logement et de la Recherche J.-M. Nollet, Royaume de Belgique, visite la salle de contrôle de CMS au Point 5, la caverne expérimentale CMS et le hall de tests des aimants supraconducteurs du LHC. Les chefs de département T. Lagrange et F. Hemmer accompagnent la délégation. L. Walckiers guide la visite SM18.

  8. 15 janvier 2014 - A. Manoha, Présidente du Tribunal de Grande Instance de Bourg-en-Bresse en France, visite le tunnel du LHC au Point 5 avec R. Garoby, Chef adjoint du département Faisceaux; visite la caverne de l'expérience CMS avec D. Contardo, Chef du projet CMS Upgrade et signe le livre d'or avec R. Garoby. F. Eder, Délégué aux relations avec les Etats-hôtes du CERN présent.

    CERN Document Server

    Pantelia, Anna

    2014-01-01

    15 janvier 2014 - A. Manoha, Présidente du Tribunal de Grande Instance de Bourg-en-Bresse en France, visite le tunnel du LHC au Point 5 avec R. Garoby, Chef adjoint du département Faisceaux; visite la caverne de l'expérience CMS avec D. Contardo, Chef du projet CMS Upgrade et signe le livre d'or avec R. Garoby. F. Eder, Délégué aux relations avec les Etats-hôtes du CERN présent.

  9. 29 August 2013 - J.-F. Jauslin, Directeur de l’Office fédéral de la culture (OFC) Ambassadeur suisse auprès de l’UNESCO et de l’OIF au 1er septembre 2013 Confédération suisse visite le centre visiteurs de l’expérience ATLAS ainsi que la caverne expérimentale d'ATLAS avec P. Jenny, ancien Porte-parole d'ATLAS. M. Bona, Conseiller du Directeur général pour les relations avec les Organisations internationales présent tout au long.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    29 August 2013 - J.-F. Jauslin, Directeur de l’Office fédéral de la culture (OFC) Ambassadeur suisse auprès de l’UNESCO et de l’OIF au 1er septembre 2013 Confédération suisse visite le centre visiteurs de l’expérience ATLAS ainsi que la caverne expérimentale d'ATLAS avec P. Jenny, ancien Porte-parole d'ATLAS. M. Bona, Conseiller du Directeur général pour les relations avec les Organisations internationales présent tout au long.

  10. 11 June 2013- Autrian Federal President Dr Heinz Fischer and Federal Minister Prof. Dr Karlheinz Töchterle visit CMS cavern and LHC tunnel at Point 5 and the ASACUSA and AEGIS experiments on the AD. Signature of the guest book in the Globe of Science and Innovation after a round table with 10 young austrian scientists. Family photograph in front of an LHC magnet.

    CERN Multimedia

    TEAM VMO

    2013-01-01

    Welcome line: on French territory by the Representative of the French Republic S. Donnot, Sous-Préfet de Gex; CERN Director-General R. Heuer; Director for Research and Scientific Computing S. Bertolucci; Director for Accelerators and Technology S. Myers; Director for Administration and general Infrastructure S. Lettow; Head of Technology Department F. Bordry; CERN Austrian Circle Spokesperson F. Eder and CERN Protocol S. Molinari. First Lady and Federal Minister Töchterle follow. CERN-HI-1306154 19-32: in CMS conference room, building 3562: general presentation of the Laboratory by the DG; CERN-HI-1306154 33-43: visiting the LHC tunnel at Point 5 with Head of Technology Department F. Bordry CERN-HI-1306154 44-64: in the CMS cavern with Collaboration Spokesperson J. Incandela and CMS and Austrian Academy of Sciences C. Wulz; CERN-HI-1306154 65-90: ASACUSA with E. Widmann and AEGIS with M. Doser. CERN-HI-1306154 91-115: round table, signatures and exchange of gifts in the Globe of Science and Innovation; fa...

  11. LaJolla Spring Cave Complex - Meramec Caverns

    Science.gov (United States)

    EPA Region 7 is directing the potentially responsible party at a groundwater contamination Superfund site in Franklin County, Mo., to perform additional work to protect workers and visitors from potentially harmful exposures at LaJolla Springs Cave Complex

  12. Orsi bruni e delle caverne, antichi abitatori delle Alpi

    OpenAIRE

    Ormezzano, Daniele

    2016-01-01

    The cave bear was among the first inhabitants of the Alpine region. Several caves, in Northern Italy (Liguria and Carso), are particularly rich in bone remains of these animals. Of the two species present in Prehistoric times, the cave bear (Ursus spelaeus), whose dimensions were decisively bigger than the actual brown bear, was the most widespread.In the Alpine caves there are remains of their utilization by ancient humans, while in France can be admired the splendid paintings on the cave wa...

  13. Storage of Residual Fuel Oil in Underground Unlined Rock Caverns.

    Science.gov (United States)

    1980-12-01

    Pierre Londe France (Europe) Civil Don Coates Canada (North America) Mining Z. T. Bieniawski United States (North America) Mining X Dinnis da Gama...E. T. Brown, who has been working closely with the Commission Cochairmen, Franklin and Bieniawski , reported. Prof. Brown will edit a book on testing...because of inactivity. (Note: The Chairman of the Case History Commission was asked to name a liaison member. Dr. Z. T. Bieniawski was nominated.) 57

  14. Alan Alda visits the ATLAS Experiment cavern at CERN

    CERN Document Server

    Claudia Marcelloni

    2012-01-01

    Alan Alda, is an American actor, director, screenwriter, and author. A six-time Emmy Award and Golden Globe Award winner, he is best known for his role as Hawkeye Pierce in the TV series M*A*S*H. He is currently a Visiting Professor at the State University of New York at Stony Brook School of Journalism and a member of the advisory board of The Center for Communicating Science.[1

  15. Online radiation monitoring for the LHC machine and experimental caverns

    CERN Document Server

    Wijnands, Thijs; Tesarek, Richard; CERN. Geneva. TS Department

    2006-01-01

    With an unprecedented amount of electronic systems exposed to radiation, reduced operational efficiency due to radiation induced failures in electronic equipment has become a serious issue for the LHC. The RADMON radiation monitoring system presented here has been designed to measure radiation at the location of equipment and to provide an early warning as radiation levels start to increase. Nearly 300 monitors will provide on line measurements of the dose, dose rate, particle flux and particle fluence. The data can be visualised in real time in LHC control rooms and is stored in a database at a rate of 1 Hz. It will be shown that the system allows studying the spatio-temporal distribution of the radiation fields in the LHC.

  16. Indirect carotid- cavernous fistula — embolisation using the superior ...

    African Journals Online (AJOL)

    Kurt

    headaches, tinnitus and hyperaemia of both eyes. She had a 2-month his- tory of blurred vision and diplopia in all gaze positions. There was no histo- ry of head trauma. The patient was otherwise healthy and was a non- smoker. Physical examination revealed conjuctival chemosis without propto- sis. She had arterialisation ...

  17. View of the ATLAS cavern at SX15

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Photo 01: Coactivity in UX15: installation of the cranes and of the metallic structures. Photo 02: The ATLAS HO structure in UX15: a 12 storey metallic frame underground Photo 03: ATLAS giant structures under construction in UX15.

  18. Diffuse Cavernous Haemangioma of the Rectum: Case Report

    African Journals Online (AJOL)

    agnosis in some cases, a careful biopsy with its potential hazards of causing profuse haemorrhage may remain the only option in most others. Characteristic endoscop- ic findings are of soft, dilated, easily collapsible submu- cosal masses, ranging in color from deep wine to plum. (8). Computed tomography (CT) scans can ...

  19. Cavernous hemangioma of the tongue: A rare case report

    Directory of Open Access Journals (Sweden)

    K A Kamala

    2014-01-01

    Full Text Available Hemangiomas are developmental vascular abnormalities and more than 50% of these lesions occur in the head and neck region, with the lips, tongue, buccal mucosa, and palate most commonly involved. They are considered as hamartomas rather than true neoplasms. Here we report a case of hemangioma of the body of the tongue, discussing the diagnostic aspects and treatment modalities of such lesion and emphasizing the role of the color Doppler ultrasonography, especially in the diagnosis and treatment. Factors such as patient′s age, size and site of lesion and the proximity of lesion to vital structure are paramount in the determination of the therapeutic approach and surgical excision. Even though radiotherapy, cryotherapy, laser therapy, medical treatment, injection of sclerosing substances and the selective embolization of the lingual artery seem to have some efficacy, the author conclude that surgery is the therapy of choice in the isolated vascular lesions of the body of the tongue.

  20. Intramedullary cavernous haemangioma of spinal cord: A case ...

    African Journals Online (AJOL)

    Thoracic myelography done showed bilateral symmetrical funnelling of the contrast at the level of T5 with widening of the spinal cord, which are typical characteristics of an intramedullary mass of spinal cord. T2-T6 Laminectomy was done. Near total excision of a 4 by 2.5 cm intradural, intramedulary bluish black, necrotic, ...

  1. Major clean-up effort in the ATLAS cavern

    CERN Multimedia

    Marzio Nessi

    On Tuesday 10 October, 58 ATLAS collaborators volunteered to give a hand for a major clean-up of the ATLAS detector prior to the toroid magnet ramp-up. This special task monopolised all of the technical coordination team and eight supervisors to oversee the volunteers who were assigned to two separate five-hour shifts. The volunteers removed all sorts of loose material inside and outside the detector, focusing mainly on potentially magnetic material lost inside the detector and dirt accumulated over several months, not to mention zillions of clipped cable ties! The technical crew provided 120 garbage bags and all were used. All sorts of material that had been lost inside the detector by various people was retrieved, in particular small tools which could potentially damage the detector, as well as metallic fillings hazardous for the electronics once the magnet will be ramped up. A more detailed inspection followed for all the inside of the detector, making sure the current on the magnet could be raised to 5KA ...

  2. Endovascular treat- ment of post- traumatic carotid- cavernous ...

    African Journals Online (AJOL)

    Kurt

    often preventing balloon deflation where the balloon position was not satisfactory on trial inflations. This technique was improved by perform- ing initial test inflation of the balloon with less viscous iodinated contrast material in order to determine whether the position of the balloon was satisfactory. Once correct place-.

  3. Thyssengas profitting by the Epe cavern storage facilities

    Energy Technology Data Exchange (ETDEWEB)

    Scheler, J.

    1987-07-01

    Natural gas import contracts are limited in what concerns the supply of natural gas. However, there seem to be no limits to the gas utilities' supplies to their customers. The Thyssengas district heat company has made it its aim to balance the rigid terms of delivery and the flexible supply customers expect. Storage facilities help to achieve this aim.

  4. Cavernous sinus syndrome due to rhino-orbital-cerebral mucormycosis

    Directory of Open Access Journals (Sweden)

    Vagner Moyses Vilela

    2013-06-01

    Full Text Available The present report describes the case of a 43-year-old diabetic patient with facial pain, protruding eyes, nasal congestion and decreased right vision (involvement of the ipsilateral cranial nerves III, IV and V. Computed tomography showed diffuse sinusitis at right, cribriform plate erosion and presence of a hypodense collection in the frontal lobe with peripheral enhancement. Magnetic resonance imaging confirmed the presence of a cerebral abscess. Samples were collected from the lesion, confirming hyphae compatible with mucormycosis.

  5. Indirect carotid- cavernous fistula — embolisation using the superior ...

    African Journals Online (AJOL)

    Kurt

    embolisation may play a role as an adjunct to venous embolisation, by decreasing the magnitude of the shunt. Transvenous embolisation is prob- ably the preferred option in the majority of patients with dural arte- rio-venous malformations (AVMs) including indirect CCF.1,3 This allows preservation of the ICA. The specific.

  6. The Asian earthquakes detected in the ATLAS cavern

    CERN Multimedia

    2005-01-01

    At the end of December, mysterious vibrations were picked up by the deformation sensors under the feet that are to support the ATLAS detector. It transpired that they had detected waves produced by the earthquakes responsible for the terrible tsunami in Asia.

  7. 10 janvier 2014 - A. Kilani, Ambassadeur Représentant permanent de la Tunisie auprès de l'Office des Nations Unies à Genève et des institutions spécialisées en Suisse visite la caverne de l'expérience ATLAS avec P. Jenni, ancien porte-parole d'ATLAS; visite le tunnel du LHC au Point 1 avec J.M. Jiménez, Chef du Département Technologie et signe le livre d'or avec F. Bordry, Directeur des accélérateurs et de la technologie. P. Fassnacht, Bureau des Relations internationales, Conseiller pour la République tunisienne présent.

    CERN Multimedia

    Jean-Claude, Gadmer

    2014-01-01

    10 janvier 2014 - A. Kilani, Ambassadeur Représentant permanent de la Tunisie auprès de l'Office des Nations Unies à Genève et des institutions spécialisées en Suisse visite la caverne de l'expérience ATLAS avec P. Jenni, ancien porte-parole d'ATLAS; visite le tunnel du LHC au Point 1 avec J.M. Jiménez, Chef du Département Technologie et signe le livre d'or avec F. Bordry, Directeur des accélérateurs et de la technologie. P. Fassnacht, Bureau des Relations internationales, Conseiller pour la République tunisienne présent.

  8. Calculation of the water permeability in large scale at a rock cavern in Blekinge, Sweden

    International Nuclear Information System (INIS)

    Lindblom, U.; Granero, J.J.

    1979-08-01

    A contract for KBS, Hagconsult has interpreted water leakage date for rock chambers near the harbor of Karlshamn in Southern Sweden. The storage plant consists of four separate rock chambers, each with a ca cross sectional area of 600 m 2 and a volume of 400.000 m 3 . The bedrock consists of gray, fine-grained gneiss, named ''Blekinge kustgnejs''. Through a simple potential flow analysis, utilizing homogeneous and isotropic rock conditions, the gross hydraulic conductivity of the rock mass was estimated at 1 x 10 -8 m/s. (author)

  9. Bilateral orbital abscesses with subdural empyema and cavernous sinus thrombosis due to melioidosis in a child

    Directory of Open Access Journals (Sweden)

    Jayaraman Kogilavaani

    2014-09-01

    Full Text Available Orbital cellulitis is an emergency situation in children. Rapid diagnosis and appropriate management are mandatory to save both vision and life. In contrast, melioidosis infection causing orbital cellulitis with intracranial infection is a rare situation in children, and requires an aggressive management. Poor response or worsening of clinical condition despite appropriate management of paediatric orbital cellulitis should alert the physician of this devastating infection, especially when it occurs in those living in endemic areas.

  10. An on line radiation monitoring system for the LHC machine and experimental caverns

    CERN Document Server

    Wijnands, T; Tesarek, R

    2007-01-01

    With an unprecedented amount of electronic systems exposed to radiation, reduced operational efficiency due to radiation induced failures in electronic equipment has become a serious issue for the LHC. The RADMON radiation monitoring system presented here has been designed to measure radiation at the location of equipment and to provide an early warning as radiation levels start to increase. Nearly 300 monitors will provide on line measurements of the dose, dose rate, particle flux and particle fluence. The data can be visualised in real time in LHC control rooms and is stored in a database at a rate of 1 Hz. It will be shown that the system allows studying the spatio-temporal distribution of the radiation fields in the LHC.

  11. Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism.

    Science.gov (United States)

    Gao, Liang; Wu, Changjing; Fu, Fudong; You, Xuanhe; Ma, Xue; Qin, Feng; Li, Tao; Wang, Run; Yuan, Jiuhong

    2018-03-01

    Penile fibrosis caused by ischemic priapism (IP) adversely affects patients' erectile function. We explored the role of lysyl oxidase (LOX) in rat and human penes after ischemic priapism (IP) to verify the effects of anti-LOX in relieving penile fibrosis and preventing erectile dysfunction caused by IP in rats. Seventy-two rats were randomly divided into six groups: control group, control + β-aminopropionitrile (BAPN) group, 9 hrs group, 9 hrs + BAPN group, 24 hrs group, and 24 hrs + BAPN group. β-aminopropionitrile (BAPN), a specific inhibitor of LOX, was administered in the drinking water. At 1 week and 4 weeks, half of the rats in each group were randomly selected for the experiment. Compared to the control group, the erectile function of IP rats was significantly decreased while the expression of LOX in the corpus cavernosum was significantly up-regulated in both 9 and 24 hrs group. Proliferated fibroblasts, decreased corpus cavernosum smooth muscle cells/collagen ratios, destroyed endothelial continuity, deposited abnormal collagen and disorganized fibers were observed in IP rats. The relative content of collage I and III was not obviously different among the groups. β-aminopropionitrile (BAPN) could effectively improve the structure and erectile function of the penis, and enhance recovery. The data in this study suggests that LOX may play an important role in the fibrosis of corpus cavernosum after IP and anti-LOX may be a novel target for patients suffering with IP. © 2017 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

  12. Stability Study for a Large Cavern in Salt Rock From Slanic Prahova

    International Nuclear Information System (INIS)

    Arad, S.; Arad, V.; Onica, I.; Oprina, A.; Chipesiu, F.; Mitrica, B.; Apostu, A.; Margineanu, R.; Hulubei, H.

    2010-01-01

    The design of a large detection infrastructure for measurements of very rare events like proton decay, or neutrino astrophysics, is in preparation and has a strong support from EU by the FP7 project LAGUNA (Design of a pan-European Infrastructure for Large Apparatus studying Grand Unification and Neutrino Astrophysics). The project has the main goal to establish the best location for a huge underground detector. The location will be selected from 7 underground laboratories from Great Britain, France, Spain, Finland, Italy, Poland and Romania. The LAGUNA site will be chosen taking into account different criteria, e.g. the depth of the site i.e. the ability to absorb and shield against high energy muons, the available space and possibility to install a large volume detector inside (larger than 70 000 m 3 ), and the natural radiation background. The site proposed in Romania is located in the salt mine Slanic Prahova. Three detector types are investigated based on different active detection media: MEMPHYSwater, LENA-liquid scintillator and GLACIER-liquid argon. (author)

  13. A primary cavernous hemangioma of the thyroid gland: A case report and literature review.

    Science.gov (United States)

    Miao, Jie; Chen, Shubo; Li, Yongcai; Fu, Lin; Li, Hui

    2017-12-01

    Thyroid hemangioma is benign and associated with fine-needle aspiration (FNA) biopsy or trauma in most cases. Its differential diagnosis is very difficult. We presented the case of a 48-year-old man complained of slowly progressed swelling in the anterior neck for 20 years. Ultrasound and CT scan revealed a hypoechogenic and heterogeneous mass measuring 4 × 3.5 cm located in the right lobe of thyroid gland. Postoperative pathological and immunohistochemical examinations of the surgical specimen revealed a primary hemangioma of the thyroid gland. The patient received a right lobectomy of the thyroid. The patient had been followed up for 10 months after surgery without complications and remained asymptomatic. Primary thyroid hemangioma should be considered when there is a well-circumscribed capsule mass on medical imaging without history of FNA or any other cervical procedures or trauma.

  14. Seasonal heat storage in underground caverns. Final report; Saisonale Waermespeicherung in Grubenraeumen. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Eikmeier, B.; Mohr, M.; Unger, H.

    1999-11-01

    The solar assisted heat supply of buildings can provide an important contribution in order to achieve the targets of minimization of primary energy consumption and reduction of greenhouse gas emissions. However, the problem of the seasonal divergence between the high solar energy supply in the summer and the high demand in the winter consists; therefore seasonal heat storage is indispensable. Here, a considerable fraction of the investments must be addressed to the central reservoir. An approach towards the reduction of the investment costs for the installation of seasonal storages in the use of cavities, which are already available in mines. In the Ruhr-Area a complex net of subterranean cavities is available. For the cost estimation of solar assisted heat supply with integrated storage in mines, the reference suburban colony 'Essen-Stoppenberg' with 42 double family houses is chosen. The specific storage costs are estimated for different technical options (tunnel- or shaft storage, direct or indirect charging system). In most cases these costs are comparable to other seasonal heat storage projects. With advantageous conditions specific capital expenditures can be achieved, which are lower than those of conventional seasonal storage. However, it must be considered, that the operating costs of pit storages are expected to be higher. (orig.)

  15. ATLAS Tile Calorimeter extended barrel Side A assembly and installation in the cavern.

    CERN Multimedia

    Nikolai Topilin

    2009-01-01

    These photos belong to the self-published book by Nikolai Topilin "ATLAS Hadron Calorimeter Assembly". The book is a collection of souvenirs from the years of assembly and installation of the Tile Hadron Calorimeter, which extended from November 2002 until May 2006.

  16. ATLAS Tile Calorimeter extended barrel side C, assembly and installation in the cavern.

    CERN Multimedia

    Nikolai Topilin

    2009-01-01

    These photos belong to the self-published book by Nikolai Topilin "ATLAS Hadron Calorimeter Assembly". The book is a collection of souvenirs from the years of assembly and installation of the Tile Hadron Calorimeter, which extended from November 2002 until May 2006.

  17. Transvenous embolization of cavernous sinus dural arteriovenous fistula via angiographic occlusive inferior petrous sinus

    Directory of Open Access Journals (Sweden)

    Chao-Bao Luo

    2015-09-01

    Conclusion: Angiographic occlusive IPS of CSDAVF may be related to true occlusion of IPS or patent IPS with compartment of the IPS-CS. There is no statistically significant difference in procedural times for these two different fistula anatomies. Transvenous embolization via angiographic occlusive IPS is a safe and effective method to manage CSDAVFs.

  18. Thermal-mechanical aspects for radioactive waste storage into underground caverns

    International Nuclear Information System (INIS)

    Vieira, Alvaro.

    1985-12-01

    The thermal and mechanical behaviors of rock mass by analytical models, considering transient effects of the heat generation from radioactive wastes, are analysed. The models were applied to Brazilian gneissic type of rock, considering the usual design of vitrified waste cylinders individually installed into conveniently spaced holes. (M.C.K.) [pt

  19. Heat storage in underground caverns - measurements and simulations; Speicherung von Waerme in Grubenraeumen - Messung und Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Schaberg, A.; Krause, H.; Poetke, W. [TU Bergakademie Freiberg (Germany). Inst. fuer Waermetechnik und Technische Thermodynamik

    1997-12-01

    Among the different discussed underground concepts for longterm storing of solar or waste heat old waterfilled mines can be an interesting solution. To examine the temperature behaviour of this storage type a testing store is built in a mine belonging to the Freiberg University of Mining and Technology in Saxonia. In a longterm project temperatures are measured inside the water volume and in the adjacent rock. The temperature behaviour depends on the operating conditions. Inside the water volume temperature stratification can be observed. During loading and standstill heat is transported into the rock surrounding. A certain part of this amount of heat can be discharged again. For designing and optimizing this storage type a numerical modell is developed. The modell is validated with experimental data from the testing plant. (orig.) [Deutsch] Unter den verschiedenen, in der Diskussion stehenden Untegrund-Waermespeichern fuer Solarwaerme oder Abwaerme bieten sich auch geflutete Gruben als Waermespeicher an. Zur Untersuchung des Temperaturverhaltens dieses Speichertyps ist im Saechsischen Lehr- und Besucherbergwerk der TU Bergakademie Freiberg ein Versuchsspeicher errichtet worden. In einem Langzeitversuch wird das Temperaturfeld im Wasser und im angrenzenden Gestein aufgezeichnet. Das Temperaturverhalten ist von den Betriebsgroessen abhaengig. Im Grubenwasser stellt sich eine stabile Temperaturschichtung ein. Waehrend der Beladung und der Stillstandszeiten wird Waerme in die Gesteinsumgebung transportiert. Ein Teil dieser Waermemenge kann wider entspeichert werden. Zur Auslegung und Optimierung von Gruben-Waermespeichern ist ein numerisches Modell entwickelt worden. Das Modell ist anhand der Messergebnisse des Versuchsspeichers validiert worden. (orig.)

  20. Pure spinal epidural cavernous hemangioma: A case series of seven cases

    Directory of Open Access Journals (Sweden)

    Ignatius Ngene Esene

    2016-01-01

    Conclusion: PSECH although rare is increasing reported and ought to be included in the differential diagnosis of spinal epidural lesions. Early surgical treatment with total resection is recommended as would result in a good prognosis.

  1. Discovery Mondays - 'The civil engineering genius of the 100-metre deep underground caverns'

    CERN Multimedia

    2004-01-01

    CERN is first and foremost a place where physicists study particle collisions. But to be able to observe the infinitely small, they need huge pieces of equipment, the accelerators and detectors, whose construction, some 100 metres below the earth's surface, calls on the services of other fascinating disciplines. Take civil engineering, for example. At the next Discovery Monday, come and find out about the machines involved in the large-scale excavation and concreting work. Everyone is welcome at Microcosm, which will be specially transformed into a worksite for the occasion! Come along to Microcosm (Reception Building 33, Meyrin site) on Monday 6 September from 7:30 p.m. to 9:00 p.m. Entrance Free http://www.cern.ch/microcosm

  2. Cavernous hemangioma in the floor of oral cavity masquerading as a ranula

    Directory of Open Access Journals (Sweden)

    Puneeta Vohra

    2015-01-01

    Full Text Available A painless, bluish, submucosal swelling on one side of the floor of the mouth usually indicates the presence of a ranula. Rarely, such a swelling may be caused by an inflammatory disease process in a salivary gland, a neoplasm in the sublingual salivary gland, hemangiomas, a lymphatic nodular swelling, amyloidosis, or embryologic cysts/dermoid cyst. We report a 35-year-old female patient with swelling in the floor of her mouth that was clinically diagnosed as a ranula due to negative diascopy, the site of swelling, and the age of patient. Because of a strong clinical suspicion of a ranula, diagnostic methods such as angiography and magnetic resonance imaging (MRI were not used in our case. A preoperative diagnosis was not truly established. We report a case of hemangioma in the floor of the mouth masquerading as a ranula. Although a rarity, vascular malformations should always be ruled out by using digital subtraction angiography and MRI studies before going for surgical intervention.

  3. Surgical treatment of a large congenital cavernous hemangioma on the thorax of a foal

    DEFF Research Database (Denmark)

    Jacobsen, Stine; Christophersen, Mogens Teken; Tnibar, Aziz

    2018-01-01

    A 3-day-old male foal was presented with a fluctuant 25 × 15 cm mass on the thorax. The mass had increased in size since birth. The mass did not respond to conservative treatment consisting of aspiration of serohaemorrhagic contents and compression bandages, and it was therefore surgically remove...

  4. The simplified convergence rate calculation for salt grit backfilled caverns in rock salt

    International Nuclear Information System (INIS)

    Navarro, Martin

    2013-03-01

    Within the research and development project 3609R03210 of the German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety, different methods were investigated, which are used for the simplified calculation of convergence rates for mining cavities in salt rock that have been backfilled with crushed salt. The work concentrates on the approach of Stelte and on further developments based on this approach. The work focuses on the physical background of the approaches. Model specific limitations are discussed and possibilities for further development are pointed out. Further on, an alternative approach is presented, which implements independent material laws for the convergence of the mining cavity and the compaction of the crushed salt backfill.

  5. Selective Embolization of Bilateral Arterial Cavernous Fistulas for Posttraumatic Penile Arterial Priapism

    International Nuclear Information System (INIS)

    Lazinger, Maxwell; Beckmann, Carl F.; Cossi, Alda; Roth, Robert A.

    1996-01-01

    A 22-year-old man suffered a hiking accident with perineal trauma and developed a nonpainful priapism secondary to bilateral arterial-cavernosal fistulas. To minimize the risk of impotence in this young patient, successive selective embolizations with autologous blood clot were performed to close the fistulas. This led to an uncomplicated full recovery. No fistula was detectable on Doppler ultrasonography at 1-year follow-up. Review of the literature confirms the safety of embolization with autologous clot

  6. Swedish-American cooperative program on radioactive waste storage in mined caverns. Technical project report No. 1

    International Nuclear Information System (INIS)

    Witherspoon, P.A.; Degerman, O.

    1978-05-01

    The Swedish-American cooperative program of investigations at the Stripa iron-ore mine is the first international effort of its kind in which field work will be carried out aimed at the general problem of underground radioactive waste storage. The program will focus on a number of problems that must be solved in developing the technology needed to design and operate waste repositories in crystalline rock. These involve such items as the appropriate mining techniques for repository construction, the effects of pressure and temperature on rock permeability, in situ rock stress measurements, and geochemical groundwater investigations. Two critical problems that will receive considerable investigation are (1) the effects of elevated temperatures on the geomechanical behavior of granite, and (2) the fracture hydrology of the granite rock mass at Stripa. The investigation of temperature effects will be approached from two standpoints: (1) the short-term effects will be studied by using full-size canisters equipped with electric heaters to simulate the energy output of radioactive waste, and (2) the long-term effects, by using a time-scaled array of electric heaters to simulate the thermal loading on a rock mass over periods of several decades. The purpose of the hydrology studies is to define the surface and subsurface hydrological conditions of the fractured granite mass at Stripa and to determine how these conditions vary as a function of time and temperature. An understanding of the rate at which water is able to seep through the rock walls of an underground opening and of the level of accuracy required for the necessary field measurements is vital to the design of a waste repository

  7. Fauna cavernícola brasileira: composição e caracterização preliminar

    Directory of Open Access Journals (Sweden)

    Eleonora Trajano

    1986-01-01

    Full Text Available In this study a number of caves from various Brazilian limestone regions were surveyed. The information gathered expands and improves that of our preliminary article, allowing a reasonable good picture of the Brazilian cave fauna. There doesn't seem to be any striking difference between the composition of the Brazilian cave fauna and that of the other tropical regions that have been studied. Animals commonly found throughout the studied area include: Phalangopsidae crickets, Reduviidae heteropterans, Polydesmida and Juliformida millipedes, Opilionida Laniatores, and spiders, particularly Scytodidae, Ctenidae, Theridiosomatidae and Pholcidae. Among the vertebrates the commonest are barts and catfishes. Amblypygi are common in all regions except São Paulo State, which is outside the group geographical distribution. Cockroaches are frequent in the warm caves to the north of Vale do Ribeira (São Paulo State where these animals are rarely seen. The cave fauna of the Vale do Ribeira is better Known than that of other Brazilian regions. Those small secretive species often found in Vale do Ribeira are probable also common elsewhere: beetles (partilarly the Carabidae, Leiodidae Catopinae, and, to a lesser exyent, the Pselaphidae and Otilodactylidae; dipterans (in special Chironomidae and Keroplatidae; and typically soil animals like collembolans and earthwormos. The sandstone cave fauna is basically the same found in limestone. The only difference seems to be the larger amount of batguano found in the former, conditioning larger populations of guano-feeding arthropods such as crickets and juliformid millipedes. The fauna of the entrance and twilight zone is characterized by the predominance of the Arachnida like opilionids Goniosominae and spiders Pholcidae, and heteropterans Reduviidae; the only typical dipteran of this fauna is the larval form of the fungus gnat Neoditomyia sp. (Mycetophiloidea. It was also observed a stratification within the studied cave communities as a result of the preference of various species toward determined substrates. As in other tropical regions, terrestrial predator troglobites are rare in Brazil, in contrast with temperate caves, characterized by a larger number of such species (particularly among the spiders and beetles. For Brazil only a genus of carabid beetle (Schizogenius spp , an unidentified species of pselaphidae beetle and some pseudoscorpions, among the terrestrial predators, have been found bearing troglomorphic characters. The Brazilian troglobites are mainly aquatic organisms (catfishes and crustaceans or terrestrial detritivores/omnivores like isopods and polydesmide millipeds.

  8. Giant cavernous hemangioma coexistent with diffuse hepatic hemangiomatosis presenting as portal vein thrombosis and hepatic lobar atrophy

    Directory of Open Access Journals (Sweden)

    Bo Reum Yoo

    2014-01-01

    Full Text Available

    A combination of giant hepatic hemangioma and diffuse hemangiomatosis is extremely rare in adults. Even when they are large, hemangiomas are soft and rarely compress adjacent structures. A 78-year-old man presented with abdominal pain and distension. Ultrasonography, computed tomography, and magnetic resonance imaging demonstrated a large expansile mass replacing the medial segment and caudate lobe with diffusely scattered nodules in the entire liver. The large hilar mass contained a central nonenhancing area and had a mass effect, leading to left portal vein occlusion. The image findings also revealed two unprecedented findings: left lateral segmental atrophy of the liver and recent portomesenteric vein thrombosis. The hepatic lesions were confirmed with hemangiomas by ultrasonography-guided biopsy. We diagnosed intrahepatic portal vein obstruction caused by a mass effect of giant hepatic hemangioma coexistent with diffuse hemangiomatosis, resulting in hepatic segmental atrophy and extrahepatic portal vein thrombosis.

  9. Is cystic mesenchymal hamartoma of the liver similar to infantile hemangioendothelioma and cavernous hemangioma on dynamic computed tomography?

    International Nuclear Information System (INIS)

    Kaufman, R.A.

    1992-01-01

    Dynamic incremental contrast CT of a cystic mesenchymal hamartoma of the liver in a 10 year old boy demonstrated peripheral and septae enhancement with partial centripetal fill-in during the next sixty minutes, not unlike that which occurs in hemangioendothelioma and hemangioma. Histologic similarities among these mesenchymal lesions may explain the similar CT and angiographic characteristics of such malformations. (orig.)

  10. Novel Optical Methods for Identification, Imaging, and Preservation of the Cavernous Nerves Responsible for Penile Erections during Prostate Cancer Surgery

    Science.gov (United States)

    2011-03-01

    of posterior retinal layers in spectral optical coher- ence tomography images of the normal retina and retinal patholo- gies,” J. Biomed. Opt. 124...analysis of fibrovascular pigmentepithelial detachment using high-definition optical coherence tomography,” Br. J. Oph- thamol. 92, 197–203 2008. 5. T

  11. CT and MR imaging of non-cavernous cranial dural arteriovenous fistulas: Findings associated with cortical venous reflux

    Energy Technology Data Exchange (ETDEWEB)

    Letourneau-Guillon, Laurent; Cruz, Juan Pablo; Krings, Timo, E-mail: Timo.Krings@uhn.ca

    2015-08-15

    Highlights: • The conventional neuroimaging manifestations of dural arteriovenous fistulas are highly variable. • Identification of cortical venous reflux is important to prevent complications. • Tortuous and dilated vessels without a nidus are associated with cortical venous reflux. • Digital subtraction angiography remains the gold standard for DAVF diagnosis. - Abstract: Purpose: To compare the conventional CT and MR findings of DAVFs in relation to the venous drainage pattern on digital subtraction angiography (DSA). Materials and Methods: Cross-sectional imaging findings (CT and/or MR) in 92 patients were compared to the presence of cortical venous reflux (CVR) on DSA. Results: Imaging features significantly more prevalent in patients with CVR included: abnormally dilated and tortuous leptomeningeal vessels (92% vs. 4%, p < 0.001) or medullary vessels (69% vs. 0%, p < 0.001), venous ectasias (45% vs. 0%, p < 0.001) and focal vasogenic edema (38% vs. 0%, p < 0.001). The following findings trended towards association but did not reach the p value established following Bonferroni correction: dilated external carotid artery branches (71% vs. 38%, p = 0.005), cluster of vessels surrounding dural venous sinus (50% vs. 19%, p = 0.009), presence of hemorrhage (33 vs. 12%, p = 0.040), and parenchymal enhancement (21% vs. 0%, p = 0.030). Conclusion: In the appropriate clinical setting, recognition of ancillary signs presumably related to venous arterialization and congestion as well as arterial feeder hypertrophy should prompt DSA confirmation to identify DAVFs associated with CVR.

  12. Endovascular treatment of unruptured aneurysms of cavernous and ophthalmic segment of internal carotid artery with flow diverter device Pipeline

    Directory of Open Access Journals (Sweden)

    Jevsek Marko

    2016-12-01

    Full Text Available Intra-arterial treatment of aneurysms by redirecting blood flow is a newer method. The redirection is based on a significantly more densely braided wire stent. The stent wall keeps the blood in the lumen of the stent and slows down the turbulent flow in the aneurysms. Stagnation of blood in the aneurysm sac leads to the formation of thrombus and subsequent exclusion of the aneurysm from the circulation. The aim of the study was to evaluate flow diverter device Pipeline for broad neck and giant aneurysm treatment.

  13. Endovascular treatment of unruptured aneurysms of cavernous and ophthalmic segment of internal carotid artery with flow diverter device Pipeline.

    Science.gov (United States)

    Jevsek, Marko; Mounayer, Charbel; Seruga, Tomaz

    2016-12-01

    Intra-arterial treatment of aneurysms by redirecting blood flow is a newer method. The redirection is based on a significantly more densely braided wire stent. The stent wall keeps the blood in the lumen of the stent and slows down the turbulent flow in the aneurysms. Stagnation of blood in the aneurysm sac leads to the formation of thrombus and subsequent exclusion of the aneurysm from the circulation. The aim of the study was to evaluate flow diverter device Pipeline for broad neck and giant aneurysm treatment. Fifteen patients with discovered aneurysm of the internal carotid artery were treated between November 2010 and February 2014. The majority of aneurysms of the internal carotid artery were located intradural at the ophthalmic part of the artery. The patients were treated using a flow diverter device Pipeline, which was placed over the aneurysm neck. Treatment success was assessed clinically and angiographically using O'Kelly Marotta scale. Control angiography immediately after the release of the stent showed stagnation of the blood flow in the aneurysm sac. In none of the patients procedural and periprocedural complications were observed. 6 months after the procedure, control CT or MR angiography showed in almost all cases exclusion of the aneurysm from the circulation and normal blood flow in the treated artery. Neurological status six months after the procedure was normal in all patients. Treatment of aneurysms with flow diverter Pipeline device is a safe and significantly less time consuming method in comparison with standard techniques. This new method is a promising approach in treatment of broad neck aneurysms.

  14. Three dimensional simulation for bayou choctaw strategic petroleum reserve (SPR).

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L. (Sandia National Laboratories, Albuquerque, NM); Park, Byoung Yoon; Lee, Moo Yul

    2006-12-01

    Three dimensional finite element analyses were performed to evaluate the structural integrity of the caverns located at the Bayou Choctaw (BC) site which is considered a candidate for expansion. Fifteen active and nine abandoned caverns exist at BC, with a total cavern volume of some 164 MMB. A 3D model allowing control of each cavern individually was constructed because the location and depth of caverns and the date of excavation are irregular. The total cavern volume has practical interest, as this void space affects total creep closure in the BC salt mass. Operations including both cavern workover, where wellhead pressures are temporarily reduced to atmospheric, and cavern enlargement due to leaching during oil drawdowns that use water to displace the oil from the caverns, were modeled to account for as many as the five future oil drawdowns in the six SPR caverns. The impacts on cavern stability, underground creep closure, surface subsidence, infrastructure, and well integrity were quantified.

  15. Composição da fauna cavernícola brasileira, com uma análise preliminar da distribuição dos taxons

    Directory of Open Access Journals (Sweden)

    Eleonora Trajano

    1990-01-01

    Full Text Available New data on Brazilian cave fauna are added to previous surveys and the relative abundance and distribution of the cavernicolous taxa is discussed. Terrestrial representatives of several arthropod families and genera are common in both tropical and subtropical Brazilian caves: Endecous and Eidmanacris crickets, Reduviidae heteropterans, Carabidae, Catopinae and Ptilodactylidae beetles, dipterans such as the Chironomidae, Keroplatidae, Phoridae and Drosophilidae, Hydropsychidae trichopterans, Pseudonnanolenidae and Chelodesnidae millipedes, Plato, Ctenus, Loxosceles and Blechroscelis spiders, Pachylinae opilionids, Chernetidae pseudoscorpions and acarians such as the Macrochelidae and Uropodidae. Other taxa are mainly or exclusively tropical Blattelidae, Blattidae and BlaberidaE cockroaches, Histeridae beetles, Noctuoidea moths, social insects as termites and ants, Styloniscidae isopods, Migalomorpha spiders, Amblypigi On the other hand, Psauridae spiders, Goniosoma and Tricommatinae opilionids, Elmidae beetles, and Philosciidae isopods seems to be mainly subtropical. Brazilian aquatic cave fauna seems to be less diversified than the terrestrial one. Siluriform fishes such as pimelodids, trichomycterids and loricariids predominate throughout the country, besides decapod (Macrobrachium shrimps, Potamidae crabs, Aegla anomurans, the latter exclusive of subtropical caves and amphipod (Spelaeogammarus, in tropical caves, and Hyalella crustaceans. Insect larvae (e.g. Elmidae coleopterans, Nematocera dipterans, trichopterans and adults (e.g. Veliidae and Naucoridae heteropterans, Dytiscidae coleopterans, oligochaetes and gastropods such as the Hydrobiidae, are also relatively common. Blechroscelis spiders, Goniosoma opilionids, Zelurus heteropterans, Eidmanacris crickets, Keroplatidae dipterans and Macrobrachium shrimps, among others, live next to the entrance zone in the majority of the caves. But, these animals become troglofiles under certain circunstances (an exceptional input of energy, or the absence of competition with cave-adapted species more efficient.

  16. The Armenian minister for trade and economic development Karen Chshmaritian, visited CERN on 4 July and toured the ATLAS experimental cavern and assembly hall

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Armenian Minister for Trade and Economic Development, K. Chshmaritian third from right with from left to right : Aram Kotzinian, JINR, Dubna; Dr Marzio Nessi, ATLAS, Zohrad Mnatsakanian, Ambassador at the Permanent Mission of the Republic of Armenia in Geneva, Karen Chshmaritian, Armenian Minister for Trade and Economic Development, Alexey Sissakian, Vice-Director of JINR and Peter Jenni, ATLAS Spokesperson.

  17. Mesure des champs de radiation dans le detecteur ATLAS et sa caverne avec les detecteurs au silicium a pixels ATLAS-MPX

    Science.gov (United States)

    Bouchami, Jihene

    The LHC proton-proton collisions create a hard radiation environment in the ATLAS detector. In order to quantify the effects of this environment on the detector performance and human safety, several Monte Carlo simulations have been performed. However, direct measurement is indispensable to monitor radiation levels in ATLAS and also to verify the simulation predictions. For this purpose, sixteen ATLAS-MPX devices have been installed at various positions in the ATLAS experimental and technical areas. They are composed of a pixelated silicon detector called MPX whose active surface is partially covered with converter layers for the detection of thermal, slow and fast neutrons. The ATLAS-MPX devices perform real-time measurement of radiation fields by recording the detected particle tracks as raster images. The analysis of the acquired images allows the identification of the detected particle types by the shapes of their tracks. For this aim, a pattern recognition software called MAFalda has been conceived. Since the tracks of strongly ionizing particles are influenced by charge sharing between adjacent pixels, a semi-empirical model describing this effect has been developed. Using this model, the energy of strongly ionizing particles can be estimated from the size of their tracks. The converter layers covering each ATLAS-MPX device form six different regions. The efficiency of each region to detect thermal, slow and fast neutrons has been determined by calibration measurements with known sources. The study of the ATLAS-MPX devices response to the radiation produced by proton-proton collisions at a center of mass energy of 7 TeV has demonstrated that the number of recorded tracks is proportional to the LHC luminosity. This result allows the ATLAS-MPX devices to be employed as luminosity monitors. To perform an absolute luminosity measurement and calibration with these devices, the van der Meer method based on the LHC beam parameters has been proposed. Since the ATLAS-MPX devices response and the luminosity are correlated, the results of measuring radiation levels are expressed in terms of particle fluences per unit integrated luminosity. A significant deviation has been obtained when comparing these fluences with those predicted by GCALOR, which is one of the ATLAS detector simulations. In addition, radiation measurements performed at the end of proton-proton collisions have demonstrated that the decay of radionuclides produced during collisions can be observed with the ATLAS-MPX devices. The residual activation of ATLAS components can be measured with these devices by means of ambient dose equivalent calibration. Keywords: pattern recognition, charge sharing effect, neutron detection efficiency, luminosity, van der Meer method, particle fluences, GCALOR simulation, residual activation, ambient dose equivalent.

  18. Prediction of postoperative outcome with special respect to removal of hemosiderin fringe: a study in patients with cavernous haemangiomas associated with symptomatic epilepsy.

    Science.gov (United States)

    Hammen, T; Romstöck, J; Dörfler, A; Kerling, F; Buchfelder, M; Stefan, H

    2007-04-01

    In this study 30 patients with symptomatic epilepsy caused by cavernomas were investigated in a postoperative follow up study to assess predictors for postoperative outcome with respect to indications, time and approach of surgery. Thirty patients with cavernomas refractory to medical treatment were scheduled for surgery based on the findings of high-resolution MR imaging and intensive EEG-video monitoring. Postoperative outcome of epilepsy was assessed by follow-up examinations based on the basis of classification by Engel and the International League against epilepsy (ILAE). The following variables were associated with good postoperative outcome: (1) complete resection of hemosiderin fringe surrounding the cavernoma was correlated to less postoperative seizure frequency versus incomplete resection of the hemosiderin fringe according to the outcome protocol of ILAE. (2) Lower duration of epilepsy at the time of operation was correlated to a better postoperative outcome with a benefit for recovery. (3) Absence of hemorrhage before surgery and unifocal seizure onset was a predictor for a favorable outcome, whereas bilateral or multifocal seizure onset zones showed poorer postoperative outcomes. (4) In patients with dual pathology (hippocampal sclerosis in addition to a cavernoma), lesionectomy plus hippocampectomy as opposed to lesionectomy only, had a better outcome than single lesionectomy. Postoperative outcome in patients with cavernomas should be the topic of further prospective multicenter studies involving a large number of patients. In addition to the ideal operation time and handling of dual pathology the role of extended resection including perilesional hemorrhages should be taken into account.

  19. 9th May 2008 - Members of Saudi government visiting ATLAS control room and cavern with Technical Coordinator M. Nessi and Adviser to the Director-General D. Blechschmidt.

    CERN Multimedia

    Mona Schweizer

    2008-01-01

    CERN-HI-0804043 05: from left to right 1st row Mrs. Ibtesam Badhrees, ATLAS Collaboration user Mr. Nadhmi Al-Nassr, Interim President, King Abdullah University of Science and Technology, KAUST H.E. Dr. Khaled S. Al-Sultan, Rector, King Fahd University for Petroleum and Minerals Mr. Abdallah S. Jum’ah, President and Chief Executive Officer, Saudi Aramco H.E. Dr. Ibrahim A. Al-Assaf, Minister of Finance H.E. Dr. Abdul Rahman Al-Tuwaijri, Chairman of Capital Markets Authority H.E. Dr. Mohammed I. Al-Suwaiyel, President, King Abdul Aziz City for Science & Technology KACST; 2nd row Mr. Salim S. Al-Aydh, Senior Vice President – Engineering & Project Management, Saudi Aramco Mr. Khalid A. Al-Falih, Executive Vice President – Operations, Saudi Aramco Mr. A. Othman, Saudi Aramco Mr. Peter Woicke, Member of the Saudi Aramco Board of Directors Mr. Abdulaziz F. Al-Khayyal, Senior Vice President – Industrial Relations, Saudi Aramco Mr. James W. Kinnear, Retired President & Chief Executive Office...

  20. 20 April 2011 - President of the European Commission J.M. Barroso visiting the LHC tunnel at Point 5 and CMS experimental cavern.

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    CERN-HI-1104125 02 - 18: President Barroso is welcomed in the French territory by the Representative of the French Republic O. Laurens-Bernard, Sous-Préfet de Gex, then, in the welcome line, CERN Director General introduces: Director for Research and Scientific Computing S. Bertolucci Portuguese Delegate to CERN Council G. Barreira Head of International Relations F. Pauss Head of Physics Department P. Bloch Head of Technology Department F. Bordry Head of Beams Department P. Collier Head of Information Technology Department F. Hemmer CMS Collaboration Spokesperson G. Tonelli Project Coordinator of FP7 EuCARD J.-P. Koutchouk and CERN EU Projects Leader S. Stavrev. From left to right on CERN-HI-1104125 91: Head of the EU Delegation to the WTO A. Pangratis;General Director, DG Research and Innovation, European Commission R. J. Smits; CERN Director for Research and Scientific Computing S. Bertolucci; Head of International Relations F. Pauss; President of the European Commission J. M. Barroso;CERN Director-Genera...

  1. Visit of the ATLAS cavern by Prof. Murray Gell-Mann, Physics Nobel 1969. With Dr Peter Jenni and Dr Alison Lister

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    Murray Gell-Mann, well known for proposing the quark model and as a recipient of the Nobel Prize in Physics in 1969, came to CERN on 23 January. During his visit he gave a theoretical physics seminar on decoherent histories in quantum mechanics.

  2. Case report

    African Journals Online (AJOL)

    abp

    2017-10-10

    Oct 10, 2017 ... Abstract. The cavernous hemangioma is a rare benign vascular tumor. About 50 cases of this disease were found in the literature over the last century and only 9 cases of cavernous hemangioma on the pregnant uterus were published it comes into cavernous or capillary form. The symptomatology is.

  3. Expansion analyses of strategic petroleum reserve in Bayou Choctaw : revised locations.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L.; Park, Byoung Yoon

    2010-11-01

    This report summarizes a series of three-dimensional simulations for the Bayou Choctaw Strategic Petroleum Reserve. The U.S. Department of Energy plans to leach two new caverns and convert one of the existing caverns within the Bayou Choctaw salt dome to expand its petroleum reserve storage capacity. An existing finite element mesh from previous analyses is modified by changing the locations of two caverns. The structural integrity of the three expansion caverns and the interaction between all the caverns in the dome are investigated. The impacts of the expansion on underground creep closure, surface subsidence, infrastructure, and well integrity are quantified. Two scenarios were used for the duration and timing of workover conditions where wellhead pressures are temporarily reduced to atmospheric pressure. The three expansion caverns are predicted to be structurally stable against tensile failure for both scenarios. Dilatant failure is not expected within the vicinity of the expansion caverns. Damage to surface structures is not predicted and there is not a marked increase in surface strains due to the presence of the three expansion caverns. The wells into the caverns should not undergo yield. The results show that from a structural viewpoint, the locations of the two newly proposed expansion caverns are acceptable, and all three expansion caverns can be safely constructed and operated.

  4. ¿Y antes de Fauchard qué? La odontología en las cavernas, los templos, los hospitales y las universidades And what was there before Fauchard? Dentistry in caverns, temples, hospitals and universities

    Directory of Open Access Journals (Sweden)

    H Ramírez Skinner

    2012-04-01

    Full Text Available Este trabajo muestra los orígenes de la odontología entre los primitivos habitantes del planeta, entre los médicos de la Antigüedad, el Renacimiento y la Edad Media hasta los tiempos modernos y la instauración del concepto de hospital clínico universitario. Sostiene que la práctica de la odontología es por definición un acto médico que tiene por objeto al ser humano en la sociedad y la salud a restablecer como bien único e indivisible, siendo ambos conceptos los que delimitan y enmarcan toda la práctica médica. La odontología nace junto con el ser humano, junto con el enfermar, el envejecer y el morir.This paper shows the origin of dentistry among the primitive inhabitants of the planet, the physicians of the Antiquity, Renaissance and Middle Ages up to the modern times and the establishment of the concept of university clinical hospital. It endorses the practice of dentistry by definition as a medical act that has the human being in the society as the object of the act itself, and the health to restore as the one and indivisible good to enhance. Both concepts are the limits and natural frame of all the medical practice. Dentistry was born with the human being, together with getting sick, ageing and dying.

  5. 3rd February 2011-Science Museum Patrons-Kingdom of Great Britain and Northern Ireland-visiting CMS cavern and LHC Tunnel with A. De Roeck,CMS Collaboration Deputy Spokesperson and M. Lamont,Beams Department, Operation Group Leader

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    The delegation: Mr Ian Blatchford,Director of the Science Museum and NMSI Mrs Susan Fisher,Director of Development, National Museum of Science and Industry (NMSI) Dr Douglas Gurr,Chairman of the Board of Trustees, NMSI Mr Martin Smith,Previous NMSI trustee Mrs Elise Smith,Spouse Mr Michael Wilson,NMSI trustee Mrs Jane Wilson,Spouse Mr Gregg Wilson,Son Dr Ann Coxon,UK Friends of the Science Museum Trustee Mr Nicholas Lewis,Contact of Martin Smith accompanied by P. Wells,Physics Department, ATLAS Inner Detector Group Leader and A. Koek,Communication group (International Arts Development, CERN Cultural Policy and Strategy with the Arts, The Collide Programme)

  6. Fractionated stereotactic radiotherapy: results in pituitary adenomas, acoustic neuromas and cavernous meningiomas; Radiotherapie stereotaxique fractionnee: resultats dans les adenomes hypophysaires, les neurinomes de l`acoustique et les meningiomes du sinus caverneux

    Energy Technology Data Exchange (ETDEWEB)

    Colin, P.; Redon, C. [Polyclinique Courlancy, 51 - Reims (France); Scavarda, D.; Delemer, B.; Nakib, I.; Caron, J.; Bazin, A.; Bernard, M.H.; Peruzzi, P.; Scherpereel, B.; Rousseaux, P. [Centre Hospitalier Universitaire, 51 - Reims (France); Fauchon, V. [Centre de Hautes Energies, 06 - Teymeinade (France); Delannes, M. [Centre Claudius-Regaud, 31 - Toulouse (France)

    1998-03-01

    In order to optimize cerebral benign tumor irradiation, fractionated stereotactic radiotherapy allows a focused-volume irradiation (2.1 cm{sup 3}, 16 mm diameter) under standard fractionation conditions. Results of a retrospective and multicentric analysis are presented. For these benign tumors, the focused target volume obtained by the fractionated stereotactic radiotherapy seems to be better adapted to the treatment of limited benign tumors than standard radiotherapy. The use of standard fractionation reduces the risk of severe normal tissue damage, sometimes observed for radiosurgery and inherent in the use of single fraction. (authors)

  7. Method to increase the safety of a final storage site in a salt cavern filled with solidified radioactive waste with regard to unforeseen rock movements and/or water ingress into cavities of the final storage site

    International Nuclear Information System (INIS)

    Koester, R.; Rudolph, G.; Kroebel, R.

    1986-01-01

    The wastes of weak or average radio-activity (e.g. T) are stored in barrels in a salt mine. In order to prevent leaching of the waste after the ingress of water into the salt mine, the intermediate spaces between the barrels are filled with a concrete grout. This grout consists of a water/bentonite/cement mixture, to which sand may be added, and which hardens. It forms a monolithic block. (orig./PW)

  8. Dinámica poblacional, selección de sitios de percha y patrones reproductivos de algunos murciélagos cavernícolas en el oeste de México

    Directory of Open Access Journals (Sweden)

    José Williams Torres-Flores

    2012-09-01

    Full Text Available Estudiamos la ecología poblacional y reproducción de algunas especies de murciélagos presentes en una cueva del oeste de México. Entre agosto 2003-marzo 2005 capturamos 16 409 individuos de los cuales 86.7% pertenecieron a miembros de la familia Mormoopidae, 7.4% a Phyllostomidae, 5.8% a N. mexicanus y 0.1% a B. plicata. Los números poblacionales de las especies varían notablemente a lo largo del año y entre temporadas. Segregación sexual durante la época reproductiva sucede en Pteronotus y N. mexicanus. Los mormópidos y N. mexicanus ocuparon las partes más profundas de la cueva donde imperan temperaturas >25.8°C y humedad >99%. Los filostómidos ocuparon las secciones intermedias con temperaturas de 23.2-28.3°C y humedad de 74-89.9%; B. plicata y G. sylvestris ocuparon una cámara con temperatura de 23.2°C y humedad del 84.2%. Los mormópidos y N. mexicanus exhibieron un patrón monoéstrico estacional, G. soricina presentó un patrón poliéstrico bimodal estacional y M. waterhousii exhibió un patrón reproductivo continuo. Nuestros resultados indican un reemplazamiento estacional entre varias especies, así como movimientos estacionales hacia otras cuevas. La selección de los sitios de percha esta ligada a las condiciones microclimáticas del refugio y la fisiología de las especies. La reproducción de las especies insectívoras esta influida por la precipitación que determina la disponibilidad del alimento.

  9. 14 April 2014 - UK University College London Hospitals and National Health Service Foundation Trust Chairman R. Murley in the ATLAS cavern with CERN Head of Medical Applications S. Myers and Collaboration Spokesperson D. Charlton.

    CERN Multimedia

    Gadmer, Jean-Claude

    2014-01-01

    Mr Richard Murley Chairman Sir Robert Naylor Chief Executive University College London Hospitals (UCLH) – National Health Service (NHS) Foundation Trust United Kingdom of Great Britain and Northern Ireland

  10. Lino Baranao, President of the National Agency for the Promotion of Science and Technology in Argentina, toured the ATLAS experiment's underground cavern during his visit to CERN on 9 May

    CERN Document Server

    Patrice Loïez

    2005-01-01

    Picture 01 : Here he is seen with ATLAS spokesperson, Peter Jenni (left), and the ATLAS Muon System project leader, Giora Mikenberg, listening to Karina Loureiro (right), an Argentinian student at the University of Wisconsin

  11. 18 December 2012 - British University of Edinburgh Principal T. O’Shea and delegation (see list below) visiting the CERN Control Centre with Beams Department D. Nisbet, the LHC superconducting magnet test hall with Beams Department R. Veness, in the ATLAS Visitor Centre and experimental cavern with Collaboration Spokesperson F. Gianotti, in LHCb experimental cavern with Collaboration Spokesperson P. Campana and signing the guest book with CERN Director-General R. Heuer

    CERN Multimedia

    Jean-Claude Gadmer

    2012-01-01

    The delegation was throughout accompanied by Beams Department R. Veness and Physics Department and ATLAS Collaboration P. Wells 1.\tProf. Sir Timothy O'Shea, Principal, University of Edinburgh 2.\tProf. Lesley Yellowlees, Vice Principal, Head of College of Science and Engineering 3.\tProf Jeff Haywood, Vice Principal for Knowledge Management 4.\tProf. Peter Higgs, Professor of Theoretical Physics 5.\tMr Bruce Minto, Supporter of the University 6.\tProf. Walter Nimmo, Supporter of the University 7.\tProf. Arthur Trew, Head of School of Physics and Astronomy 8.\tProf David Robertson, Head of School of Informatics 9.\tProf Stefano Brandani, Head of School of Engineering 10.\tMr Alan Walker, accompanying Prof. Higgs 11.\tProf. Peter Clarke, LHCb Collaboration, School of Physics and Astronomy

  12. A numerical study of the non-linear stress-strain-characteristic of rock salt using a finite element code

    International Nuclear Information System (INIS)

    Moldzio, G.

    1980-01-01

    As is shown by the results of a computer based numerical stress analysis of a storage cavern this method can provide usefull and applicable results. The method can be applied for simulating the cavern geometry and the stress distribution. Although the program NTIS is written in FORTRAN, a computer with a large core memory is necessary. The elasticity analysis confirms the advantages of an elliptically shaped cavern ceiling, which is strived for since a long time in practice. (DG) [de

  13. September 2016 Bayou Choctaw Subsidence Report

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, Dylan Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lord, Anna C. Snider [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    Subsidence monitoring is a crucial component to understanding cavern integrity of salt storage caverns. This report looks at historical and current data at the Bayou Choctaw Strategic Petroleum Reserve Site. Data from the most recent land-based annual surveys, GPS, and tiltmeter indicate the subsidence rates across the site are approximately 0.0 ft./yr. Because of this, there is no evidence from the subsidence survey to suggest any of the DOE caverns have been structurally compromised.

  14. Siting technology of underground nuclear power station

    International Nuclear Information System (INIS)

    Motojima, M.; Hibino, S.

    1989-01-01

    For the site of a nuclear power station, it may be possible to select a seaside mountain area, if the condition is suitable to excavate large rock caverns in which a reactor and other equipments are installed. As the case study on the siting technology for an underground nuclear power station, the following example was investigated. The site is a seaside steep mountain area, and almost all the equipments are installed in plural tunnel type caverns. The depth from the ground surface to the top of the reactor cavern is about 150 m, and the thickness of the rock pillar between the reactor cavern of 33 m W x 82 mH x 79 mD and the neighboring turbine cavern is 60 m. In this paper, the stability of rock caverns in this example, evaluated by numerical analysis, is described. The numerical analysis was carried out on the central cross section of the reactor cavern, taking the turbine cavern, geostress, the mechanical properties of rock mass and the process of excavation works in consideration. By the analysis, the underground caverns in this example were evaluated as stable, if the rock quality is equivalent to C H class or better according to the CRIEPI rock classification. (K.I.)

  15. sommaire N°13

    African Journals Online (AJOL)

    threatening condition and can lead to ocular sequelae. it results from an abnormal vascular interconnection between a branch of ... Keywords: carotid cavernous fistula, craniofacial trauma, cerebral angiography, embolization.

  16. 78 FR 21931 - Arlington Storage Company, LLC; Notice of Intent To Prepare an Environmental Assessment for the...

    Science.gov (United States)

    2013-04-12

    ... 500 horsepower (hp) skid-mounted compressor unit; use of Well no. 45 in debrining \\1\\ operation, and for future cavern monitoring; \\1\\ The project would ready the caverns for natural gas storage by... and temporary brine pipelines; installation of electric and instrument air lines connecting the...

  17. Case report

    African Journals Online (AJOL)

    abp

    2015-12-11

    Dec 11, 2015 ... This is an Open Access article distributed under the terms of the Creative Commons. Attribution License (http://creativecommons.org/licenses/by/2.0), which permits ... was composed of large, cavernous vascular spaces filled with blood and separated by connective tissue stroma diagnosed as cavernous.

  18. Serge Dassault, chair of the Dassault Group and Socpresse and senator of Essonne, participated in the Amicable Economic and Social Council of France at CERN on 15 June.

    CERN Multimedia

    Maximilien Brice

    2006-01-01

    Dassault visited the underground cavern of the ATLAS experiment together with his son, Olivier, and Jean Jacques Blaising, head of the Physics Department. The participants also toured the LHC magnet assembly and testing hall, and the surface assembly hall and experimental cavern of the CMS experiment.

  19. Swiss President to visit CERN

    CERN Multimedia

    2003-01-01

    "Pascal Couchepin, President of the Swiss Confederation, will visit CERN on 4 June to participate in the official inauguration of the underground cavern for the laboratory's ATLAS experiment. As the first new experimental cavern to be handed over to CERN by civil engineering contractors, this represents an important milestone for the Laboratory" (1 page).

  20. L'atteinte du sinus caverneux dans le carcinome adenoïde systique ...

    African Journals Online (AJOL)

    Introduction: Head and neck adenoid cystic carcinoma (ACC) is a malignant epithelial neoplasm, developing from salivary gland tissue. Cavernous sinus and skull base invasion by perinervous spread is a particular behavior of this tumor entity. We report two cases of cavernous sinus invasion. Cases report: The first one ...