WorldWideScience

Sample records for catastrophic incident recovery

  1. Catastrophic Incident Recovery: Long-Term Recovery from an Anthrax Event Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Lesperance, Ann M.

    2008-06-30

    On March 19, 2008, policy makers, emergency managers, and medical and Public Health officials convened in Seattle, Washington, for a workshop on Catastrophic Incident Recovery: Long-Term Recovery from an Anthrax Event. The day-long symposium was aimed at generating a dialogue about restoration and recovery through a discussion of the associated challenges that impact entire communities, including people, infrastructure, and critical systems.

  2. Adaptation to and Recovery from Global Catastrophe

    Directory of Open Access Journals (Sweden)

    Seth D. Baum

    2013-03-01

    Full Text Available Global catastrophes, such as nuclear war, pandemics and ecological collapse threaten the sustainability of human civilization. To date, most work on global catastrophes has focused on preventing the catastrophes, neglecting what happens to any catastrophe survivors. To address this gap in the literature, this paper discusses adaptation to and recovery from global catastrophe. The paper begins by discussing the importance of global catastrophe adaptation and recovery, noting that successful adaptation/recovery could have value on even astronomical scales. The paper then discusses how the adaptation/recovery could proceed and makes connections to several lines of research. Research on resilience theory is considered in detail and used to develop a new method for analyzing the environmental and social stressors that global catastrophe survivors would face. This method can help identify options for increasing survivor resilience and promoting successful adaptation and recovery. A key point is that survivors may exist in small isolated communities disconnected from global trade and, thus, must be able to survive and rebuild on their own. Understanding the conditions facing isolated survivors can help promote successful adaptation and recovery. That said, the processes of global catastrophe adaptation and recovery are highly complex and uncertain; further research would be of great value.

  3. A sustainable training strategy for improving health care following a catastrophic radiological or nuclear incident.

    Science.gov (United States)

    Blumenthal, Daniel J; Bader, Judith L; Christensen, Doran; Koerner, John; Cuellar, John; Hinds, Sidney; Crapo, John; Glassman, Erik; Potter, A Bradley; Singletary, Lynda

    2014-02-01

    The detonation of a nuclear device in a US city would be catastrophic. Enormous loss of life and injuries would characterize an incident with profound human, political, social, and economic implications. Nevertheless, most responders have not received sufficient training about ionizing radiation, principles of radiation safety, or managing, diagnosing, and treating radiation-related injuries and illnesses. Members throughout the health care delivery system, including medical first responders, hospital first receivers, and health care institution support personnel such as janitors, hospital administrators, and security personnel, lack radiation-related training. This lack of knowledge can lead to failure of these groups to respond appropriately after a nuclear detonation or other major radiation incident and limit the effectiveness of the medical response and recovery effort. Efficacy of the response can be improved by getting each group the information it needs to do its job. This paper proposes a sustainable training strategy for spreading curricula throughout the necessary communities. It classifies the members of the health care delivery system into four tiers and identifies tasks for each tier and the radiation-relevant knowledge needed to perform these tasks. By providing education through additional modules to existing training structures, connecting radioactive contamination control to daily professional practices, and augmenting these systems with just-in-time training, the strategy creates a sustainable mechanism for giving members of the health care community improved ability to respond during a radiological or nuclear crisis, reducing fatalities, mitigating injuries, and improving the resiliency of the community.

  4. Preterm infant with a catastrophic hemorrhagic-thromboembolic incident.

    Science.gov (United States)

    Abdelhamid, Adel E

    2012-01-01

    Thrombotic disease of the newborn is uncommon but usually associated with serious morbidity and mortality. Although the operating mechanisms of coagulation and fibrinolysis are the same in all age groups, plasma concentrations of the two systems' components are significantly different in neonates compared to children and adults. This places neonates at greater risk for thrombosis that may rise considerably if a predisposing factor is present or a genetic or medical condition predisposing to thrombosis coexists. While marginal, the possibility of abnormal bleeding secondary to congenital prothrombotic disorders has been described. A significant association between thromboembolic/hemorrhagic disease in newborns and each of factor V(Leiden) and prothrombin G20210A mutations has been reported. Although not a frequent occurrence in adults and children, congenital 'multigenic' thrombophilia is well known. However, the combined heterozygote state of both mutations is perhaps underreported in preterm infants. We present a severely intrauterine growth-restricted preterm baby born to consanguineous parents. He had stroke as part of a generalized bleeding-thromboembolic incident caused by combined heterozygote mutation of factor V(Leiden) and prothrombin G20210A, each of which was then found in a heterozygote form in each of the 2 parents.

  5. Recovery from chemical, biological, and radiological incidents :

    Energy Technology Data Exchange (ETDEWEB)

    Franco, David Oliver; Yang, Lynn I.; Hammer, Ann E.

    2012-06-01

    To restore regional lifeline services and economic activity as quickly as possible after a chemical, biological or radiological incident, emergency planners and managers will need to prioritize critical infrastructure across many sectors for restoration. In parallel, state and local governments will need to identify and implement measures to promote reoccupation and economy recovery in the region. This document provides guidance on predisaster planning for two of the National Disaster Recovery Framework Recovery Support Functions: Infrastructure Systems and Economic Recovery. It identifies key considerations for infrastructure restoration, outlines a process for prioritizing critical infrastructure for restoration, and identifies critical considerations for promoting regional economic recovery following a widearea disaster. Its goal is to equip members of the emergency preparedness community to systematically prioritize critical infrastructure for restoration, and to develop effective economic recovery plans in preparation for a widearea CBR disaster.

  6. From Catastrophizing to Recovery: a pilot study of a single-session treatment for pain catastrophizing

    Directory of Open Access Journals (Sweden)

    Darnall BD

    2014-04-01

    Full Text Available Beth D Darnall, John A Sturgeon, Ming-Chih Kao, Jennifer M Hah, Sean C MackeyDivision of Pain Medicine, Stanford Systems Neuroscience and Pain Laboratory, Stanford University School of Medicine, Palo Alto, CA, USABackground: Pain catastrophizing (PC – a pattern of negative cognitive-emotional responses to real or anticipated pain – maintains chronic pain and undermines medical treatments. Standard PC treatment involves multiple sessions of cognitive behavioral therapy. To provide efficient treatment, we developed a single-session, 2-hour class that solely treats PC entitled “From Catastrophizing to Recovery”[FCR].Objectives: To determine 1 feasibility of FCR; 2 participant ratings for acceptability, understandability, satisfaction, and likelihood to use the information learned; and 3 preliminary efficacy of FCR for reducing PC.Design and methods: Uncontrolled prospective pilot trial with a retrospective chart and database review component. Seventy-six patients receiving care at an outpatient pain clinic (the Stanford Pain Management Center attended the class as free treatment and 70 attendees completed and returned an anonymous survey immediately post-class. The Pain Catastrophizing Scale (PCS was administered at class check-in (baseline and at 2, and 4 weeks post-treatment. Within subjects repeated measures analysis of variance (ANOVA with Student's t-test contrasts were used to compare scores across time points.Results: All attendees who completed a baseline PCS were included as study participants (N=57; F=82%; mean age =50.2 years; PCS was completed by 46 participants at week 2 and 35 participants at week 4. Participants had significantly reduced PC at both time points (P<0001 and large effect sizes were found (Cohen's d=0.85 and d=1.15.Conclusion: Preliminary data suggest that FCR is an acceptable and effective treatment for PC. Larger, controlled studies of longer duration are needed to determine durability of response, factors

  7. Analysis of Environmental Contamination resulting from Catastrophic Incidents: Part two: Building Laboratory Capability by Selecting and Developing Analytical Methodologies

    Science.gov (United States)

    Catastrophic incidents can generate a large number of samples with analytically diverse types including forensic, clinical, environmental, food, and others. Environmental samples include water, wastewater, soil, air, urban building and infrastructure materials, and surface resid...

  8. 32 CFR 537.6 - Identification of recovery incidents.

    Science.gov (United States)

    2010-07-01

    ... for assistance with workers' compensation forms, without coordinating with the RJA or recovery... 32 National Defense 3 2010-07-01 2010-07-01 true Identification of recovery incidents. 537.6... ACCOUNTS CLAIMS ON BEHALF OF THE UNITED STATES § 537.6 Identification of recovery incidents....

  9. Vegetation recovery patterns assessment at landslides caused by catastrophic earthquake: a case study in central Taiwan.

    Science.gov (United States)

    Chou, Wen-Chieh; Lin, Wen-Tzu; Lin, Chao-Yuan

    2009-05-01

    The catastrophic earthquake, 7.3 on the Richter scale, occurred on September 21, 1999 in Central Taiwan. Much of standing vegetation on slopes was eliminated and massive, scattered landslides were induced at the Jou-Jou Mountain area of the Wu-Chi basin in Nantou County. We evaluated three methods for assessing landslide hazard and vegetation recovery conditions. (1) Self-organizing map (SOM) neural network coupled with fuzzy technique was used to quickly extract the landslide. (2) The NDVI-based vegetation recovery index derived from multi-temporal SPOT satellite images was used to evaluate vegetation recovery rate in the denudation sites. (3) The spatial distribution index (SDI) based on land-cover topographic location was employed to analyze vegetation recovery patterns, including the invading, surviving and mixed patterns at the Jou-Jou Mountain area. On September 27, 1999, there were 849.20 ha of landslide area extracted using the self-organizing map and fuzzy technique combined model. After six years of natural vegetation succession, the landslide has gradually restored, and vegetation recovery rate reached up to 86%. On-site observation shows that many native pioneer plants have invaded onto the denudation sites even if disturbed by several typhoons. Two native surviving plants, Arundo formosana Hack and Pinus taiwanensis Hayata, play a vital role in natural vegetation succession in this area, especially for the sites on ridgeline and steep slopes.

  10. Analysis of environmental contamination resulting from catastrophic incidents: part 1. Building and sustaining capacity in laboratory networks.

    Science.gov (United States)

    Magnuson, Matthew; Ernst, Hiba; Griggs, John; Fitz-James, Schatzi; Mapp, Latisha; Mullins, Marissa; Nichols, Tonya; Shah, Sanjiv; Smith, Terry; Hedrick, Elizabeth

    2014-11-01

    Catastrophic incidents, such as natural disasters, terrorist attacks, and industrial accidents, can occur suddenly and have high impact. However, they often occur at such a low frequency and in unpredictable locations that planning for the management of the consequences of a catastrophe can be difficult. For those catastrophes that result in the release of contaminants, the ability to analyze environmental samples is critical and contributes to the resilience of affected communities. Analyses of environmental samples are needed to make appropriate decisions about the course of action to restore the area affected by the contamination. Environmental samples range from soil, water, and air to vegetation, building materials, and debris. In addition, processes used to decontaminate any of these matrices may also generate wastewater and other materials that require analyses to determine the best course for proper disposal. This paper summarizes activities and programs the United States Environmental Protection Agency (USEPA) has implemented to ensure capability and capacity for the analysis of contaminated environmental samples following catastrophic incidents. USEPA's focus has been on building capability for a wide variety of contaminant classes and on ensuring national laboratory capacity for potential surges in the numbers of samples that could quickly exhaust the resources of local communities. USEPA's efforts have been designed to ensure a strong and resilient laboratory infrastructure in the United States to support communities as they respond to contamination incidents of any magnitude. The efforts include not only addressing technical issues related to the best-available methods for chemical, biological, and radiological contaminants, but also include addressing the challenges of coordination and administration of an efficient and effective response. Laboratory networks designed for responding to large scale contamination incidents can be sustained by applying

  11. Factors influencing recovery and restoration following a chemical incident.

    Science.gov (United States)

    Peña-Fernández, A; Wyke, S; Brooke, N; Duarte-Davidson, R

    2014-11-01

    Chemicals are an important part of our society. A wide range of chemicals are discharged into the environment every day from residential, commercial and industrial sources. Many of these discharges do not pose a threat to public health or the environment. However, global events have shown that chemical incidents or accidents can have severe consequences on human health, the environment and society. It is important that appropriate tools and technical guidance are available to ensure that a robust and efficient approach to developing a remediation strategy is adopted. The purpose of remediation is to protect human health from future exposure and to return the affected area back to normal as soon as possible. There are a range of recovery options (techniques or methods for remediation) that are applicable to a broad range of chemicals and incidents. Recovery options should be evaluated according to their appropriateness and efficacy for removing contaminants from the environment; however economic drivers and social and political considerations often influence decision makers on which remedial actions are implemented during the recovery phase of a chemical incident. To date, there is limited information in the literature on remediation strategies and recovery options that have been implemented following a chemical incident, or how successful they have been. Additional factors that can affect the approach taken for recovery are not well assessed or understood by decision makers involved in the remediation and restoration of the environment following a chemical incident. The identification of this gap has led to the development of the UK Recovery Handbook for Chemical Incidents to provide a framework for choosing an effective recovery strategy. A compendium of practical evidence-based recovery options (techniques or methods for remediation) for inhabited areas, food production systems and water environments has also been developed and is included in the chemical

  12. Key Planning Factors for Recovery from a Radiological Terrorism Incident

    Science.gov (United States)

    2012-09-01

    Livermore National Laboratory – Annmarie R. Wood- Zika , Lawrence Livermore National Laboratory – Robert P. Fischer, Lawrence Livermore National...recovery timeline and costs , improving public health and safety, and addressing major resource limitations and critical decisions. DHS S&T would like to...time, recovery costs , and improve public health and safety. Key Planning Factors described in these documents will help local, state, and Federal

  13. System Safety Assessment Based on Past Incidents in Oil and Gas Industries: A Focused Approach in Forecasting of Minor, Severe, Critical, and Catastrophic Incidents, 2010–2015

    Directory of Open Access Journals (Sweden)

    Praveen Patel

    2016-01-01

    Full Text Available Accident in an occupation which occurred due to series of repetitive minor incidents within the working environment. This work demonstrates the critical system safety assessment based on various incidents that took place to the different system and subsystem of two Indian oil refineries in five years of span 2010 to 2015. The categorization of incidents and hazard rate function of each incident category were classified and calculated. The result of Weibull analysis estimators in the form of scale and shape parameters provides useful information of incidents forecasting and their patterns in a particular time.

  14. Recovery from chemical, biological, and radiological incidents. Critical infrastructure and economic impact considerations

    Energy Technology Data Exchange (ETDEWEB)

    Franco, David Oliver [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Yang, Lynn I. [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Hammer, Ann E. [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2012-06-01

    To restore regional lifeline services and economic activity as quickly as possible after a chemical, biological or radiological incident, emergency planners and managers will need to prioritize critical infrastructure across many sectors for restoration. In parallel, state and local governments will need to identify and implement measures to promote reoccupation and economy recovery in the region. This document provides guidance on predisaster planning for two of the National Disaster Recovery Framework Recovery Support Functions: Infrastructure Systems and Economic Recovery. It identifies key considerations for infrastructure restoration, outlines a process for prioritizing critical infrastructure for restoration, and identifies critical considerations for promoting regional economic recovery following a widearea disaster. Its goal is to equip members of the emergency preparedness community to systematically prioritize critical infrastructure for restoration, and to develop effective economic recovery plans in preparation for a widearea CBR disaster.

  15. PREVAIL: Predicting Recovery through Estimation and Visualization of Active and Incident Lesions

    Directory of Open Access Journals (Sweden)

    Jordan D. Dworkin

    2016-01-01

    Conclusion: This study demonstrates that by using only information from a single visit at incidence, we can predict how a new lesion will recover using relatively simple statistical techniques. The potential to visualize the likely course of recovery has implications for clinical decision-making, as well as trial enrichment.

  16. Psychological impact and recovery after involvement in a patient safety incident: a repeated measures analysis

    Science.gov (United States)

    Van Gerven, Eva; Bruyneel, Luk; Panella, Massimiliano; Euwema, Martin; Sermeus, Walter; Vanhaecht, Kris

    2016-01-01

    Objective To examine individual, situational and organisational aspects that influence psychological impact and recovery of a patient safety incident on physicians, nurses and midwives. Design Cross-sectional, retrospective surveys of physicians, midwives and nurses. Setting 33 Belgian hospitals. Participants 913 clinicians (186 physicians, 682 nurses, 45 midwives) involved in a patient safety incident. Main outcome measures The Impact of Event Scale was used to retrospectively measure psychological impact of the safety incident at the time of the event and compare it with psychological impact at the time of the survey. Results Individual, situational as well as organisational aspects influenced psychological impact and recovery of a patient safety incident. Psychological impact is higher when the degree of harm for the patient is more severe, when healthcare professionals feel responsible for the incident and among female healthcare professionals. Impact of degree of harm differed across clinicians. Psychological impact is lower among more optimistic professionals. Overall, impact decreased significantly over time. This effect was more pronounced for women and for those who feel responsible for the incident. The longer ago the incident took place, the stronger impact had decreased. Also, higher psychological impact is related with the use of a more active coping and planning coping strategy, and is unrelated to support seeking coping strategies. Rendered support and a support culture reduce psychological impact, whereas a blame culture increases psychological impact. No associations were found with job experience and resilience of the health professional, the presence of a second victim support team or guideline and working in a learning culture. Conclusions Healthcare organisations should anticipate on providing their staff appropriate and timely support structures that are tailored to the healthcare professional involved in the incident and to the specific

  17. Estimation of incidence and recovery rates of Plasmodium falciparum parasitaemia from longitudinal data

    Science.gov (United States)

    Bekessy, A.; Molineaux, L.; Storey, J.

    1976-01-01

    A method is described of estimating the malaria incidence rate ĥ and the recovery rate r from longitudinal data. The method is based on the assumption that the phenomenon of patent parasitaemia can be represented by a reversible two-state catalytic model; it is applicable to all problems that can be represented by such a model. The method was applied to data on falciparum malaria from the West African savanna and the findings suggested that immunity increases the rate of recovery from patent parasitaemia by a factor of up to 10, and also reduces the number of episodes of patent parasitaemia resulting from one inoculation. Under the effect of propoxur, ĥ varies with the estimated man-biting rate of the vector while r̂ increases, possibly owing to reduced super-infection. PMID:800968

  18. Catastrophe medicine; Medecine de catastrophe

    Energy Technology Data Exchange (ETDEWEB)

    Lebreton, A. [Service Technique de l`Energie Electrique et des Grands Barrages (STEEGB), (France)

    1996-12-31

    The `Catastrophe Medicine` congress which took place in Amiens (France) in December 5 to 7 1996 was devoted to the assessment and management of risks and hazards in natural and artificial systems. The methods of risk evaluation and prevision were discussed in the context of dams accidents with the analysis of experience feedbacks and lessons gained from the organisation of emergency plans. Three round table conferences were devoted to the importance of psychological aspects during such major crises. (J.S.)

  19. Cosmic Catastrophes

    Science.gov (United States)

    Wheeler, J. Craig

    2014-08-01

    Preface; 1. Setting the stage: star formation and hydrogen burning in single stars; 2. Stellar death: the inexorable grip of gravity; 3. Dancing with stars: binary stellar evolution; 4. Accretion disks: flat stars; 5. White Dwarfs: quantum dots; 6. Supernovae: stellar catastrophes; 7. Supernova 1987A: lessons and enigmas; 8. Neutron stars: atoms with attitude; 9. Black holes in theory: into the abyss; 10. Black holes in fact: exploring the reality; 11. Gamma-ray bursts, black holes and the universe: long, long ago and far, far away; 12. Supernovae and the universe; 13. Worm holes and time machines: tunnels in space and time; 14. Beyond: the frontiers; Index.

  20. Volcanic Catastrophes

    Science.gov (United States)

    Eichelberger, J. C.

    2003-12-01

    The big news from 20th century geophysics may not be plate tectonics but rather the surprise return of catastrophism, following its apparent 19th century defeat to uniformitarianism. Divine miracles and plagues had yielded to the logic of integrating observations of everyday change over time. Yet the brilliant interpretation of the Cretaceous-Tertiary Boundary iridium anomaly introduced an empirically based catastrophism. Undoubtedly, decades of contemplating our own nuclear self-destruction played a role in this. Concepts of nuclear winter, volcanic winter, and meteor impact winter are closely allied. And once the veil of threat of all-out nuclear exchange began to lift, we could begin to imagine slower routes to destruction as "global change". As a way to end our world, fire is a good one. Three-dimensional magma chambers do not have as severe a magnitude limitation as essentially two-dimensional faults. Thus, while we have experienced earthquakes that are as big as they get, we have not experienced volcanic eruptions nearly as great as those preserved in the geologic record. The range extends to events almost three orders of magnitude greater than any eruptions of the 20th century. Such a calamity now would at the very least bring society to a temporary halt globally, and cause death and destruction on a continental scale. At maximum, there is the possibility of hindering photosynthesis and threatening life more generally. It has even been speculated that the relative genetic homogeneity of humankind derives from an evolutionary "bottleneck" from near-extinction in a volcanic cataclysm. This is somewhat more palatable to contemplate than a return to a form of Original Sin, in which we arrived at homogeneity by a sort of "ethnic cleansing". Lacking a written record of truly great eruptions, our sense of human impact must necessarily be aided by archeological and anthropological investigations. For example, there is much to be learned about the influence of

  1. Considering the unthinkable—A review and discussion of current international law and suggestions regarding how we deal with a catastrophic incident in space

    Science.gov (United States)

    Beamer-Downie, Darcy

    2013-12-01

    It is now clear that private enterprise and not nationally funded space agencies will be the driving force behind development of space for the "benefit" of private enterprise and the general public. It is also not unreasonable to say that in the next 20-30 years we will see the public accessing space via sub-orbital flights, orbital excursions, orbiting hotels and possibly even hotels located on a celestial body. The existing principles regarding the rescue and return of "astronauts" was never fit for purpose and is certainly not appropriate for this new era of private space activity. Activities in space are dangerous and the travelling public is generally risk adverse. So how do we balance the obvious risks associated with space travel, against the societal desire to seek adventures in space and with the prevailing risk adverse culture? It is now time to seriously consider the development of international safety standards for space vehicles and habitations in order to ensure that rescue and return from a space excursion is a reality for passengers and crew. If we fail to do so then the scenario set out below may become a tragic reality. Catastrophic ScenarioConsider a scenario in which a space hotel loses a significant amount of its in-orbit life support capability. Rescue is underway but it will take time. The Captain realises that there is not enough oxygen on board for all to survive until rescue. What if anything can be done?

  2. Key Planning Factors for Recovery from a Chemical Warfare Agent Incident

    Science.gov (United States)

    2012-07-01

    chemical scenario involving the release of a blister agent (mustard lewisite) would result in a waste that the State of Colorado would regulate as... Waste Management ................................................................. 24 4.3 Key Planning Factors: Recovery Planning...Planning Factors, this document presents a chemical warfare agent scenario featuring Agent Yellow, a blister agent. Agent Yellow is a mixture of

  3. Recovery from a chemical weapons accident or incident: A concept paper on planning

    Energy Technology Data Exchange (ETDEWEB)

    Herzenberg, C.L.; Haffenden, R.; Lerner, K.; Meleski, S.A.; Tanzman, E.A. [Argonne National Lab., IL (United States); Lewis, L.M. [US Dept. of Agriculture (United States); Hemphill, R.C. [Niagara Mohawk Power Corporation (United States); Adams, J.D. [US Environmental Protection Agency (United States)

    1994-04-01

    Emergency planning for an unintended release of chemical agent from the nation`s chemical weapons stockpile should include preparation for. the period following implementation of immediate emergency response. That period -- the recovery, reentry, and restoration stage -- is the subject of this report. The report provides an overview of the role of recovery, reentry, and restoration planning in the Chemical Stockpile Emergency Preparedness Program (CSEPP), describes the transition from immediate emergency response to restoration, and analyzes the legal framework that would govern restoration activities. Social, economic, and administrative issues, as well as technical ones, need to be considered in the planning effort. Because of possible jurisdictional conflicts, appropriate federal, state, and local agencies need to be included in a coordinated planning process. Advance consideration should be given to the pertinent federal and state statutes and regulations. On the federal level, the principal statutes and regulations to be considered are those associated with the Comprehensive Environmental Response, Compensation, and Liability Act; the Resource Conservation and Recovery Act; and the National Environmental Policy Act. This report recommends that extensive preaccident planning be undertaken for the recovery, reentry, and restoration stage and outlines several key issues that should be considered in that planning. The need for interagency cooperation and coordination at all levels of the planning process is emphasized.

  4. The Ongoing Catastrophe

    DEFF Research Database (Denmark)

    Kublitz, Anja

    for the girl talk is centred on catastrophes or Nakbas, as they are referred to in Arabic. Not only al-Nakba of 1948 when the Palestinians were displaced from their homeland, but also the many recurring wars and the individual catastrophes that involve dead family members, rapes, loss of children and abusive...

  5. Incidence of neurosensory deficits and recovery after lower third molar surgery: a prospective clinical study of 4338 cases.

    Science.gov (United States)

    Cheung, L K; Leung, Y Y; Chow, L K; Wong, M C M; Chan, E K K; Fok, Y H

    2010-04-01

    A prospective study of all lower third molar surgery performed in the outpatient extraction clinic of a teaching dental hospital was conducted from January 1998 through October 2005 to determine the incidence of subsequent neurosensory deficit due to inferior alveolar nerve (IAN) and lingual nerve (LN) injury, to examine possible contributing risk factors and to describe the pattern of recovery. 3595 patients were included (61% female, 39% male; age range, 14-82 years). Of the 4338 lower third molar extractions performed by various grades of operators, 0.35% developed IAN deficit and 0.69% developed LN deficit. Distoangular impaction was found to increase the risk of LN deficit significantly (pdeficit (pdeficits (pdeficits was noted most significantly at 3 and 6 months, respectively. By the end of the follow-up period, 67% of IAN deficits and 72% of LN deficits had recovered completely.

  6. Catastrophic Antiphospholipid Syndrome

    Directory of Open Access Journals (Sweden)

    Rawhya R. El-Shereef

    2016-01-01

    Full Text Available This paper reports one case of successfully treated patients suffering from a rare entity, the catastrophic antiphospholipid syndrome (CAPS. Management of this patient is discussed in detail.

  7. Habitability and cosmic catastrophes

    CERN Document Server

    Hanslmeier, Arnold; McKay, Christopher P

    2008-01-01

    Catastrophic cosmic events such as asteroid impacts appear in the range of some 100 million years and have drastically affected evolution. The author discusses whether and how such events could have occurred in recently found extrasolar planetary systems.

  8. Anthropogenic impacts to the recovery of the Mexican gray wolf with a focus on trapping-related incidents

    Science.gov (United States)

    Turnbull, Trey T.; Cain, James W.; Roemer, Gary W.

    2013-01-01

    Concerns regarding the potential negative impacts of regulated furbearer trapping to reintroduced Mexican gray wolves (Canis lupus baileyi), led to an executive order prohibiting trapping in the New Mexico, USA, portion of the Blue Range Wolf Recovery Area. This ban was to last for 6 months and required an evaluation of the risk posed to wolves by traps and snares legally permitted in New Mexico. We reviewed potential threats to wolves in the Blue Range Wolf Recovery Area, including threats associated with regulated furbearer trapping. One hundred Mexican gray wolf mortalities have been documented during the reintroduction effort (1998–2011). Of those mortalities with a known cause, >81% were human-caused resulting from illegal shooting (n = 43), vehicle collisions (n = 14), lethal removal by the United States Fish and Wildlife Service (USFWS; n = 12), non-project-related trapping (n = 2), project-related trapping (n = 1), and legal shooting by the public (n = 1). Ten wolves died due to unknown causes. The remaining 17 mortalities were a result of natural causes (e.g., starvation, disease). An additional 23 wolves were permanently, but non-lethally, removed from the wild by the USFWS. Of 13 trapping incidents in New Mexico that involved non-project trappers (i.e., trappers not associated with USFWS or U.S. Department of Agriculture-Wildlife Services), 7 incidents are known to have resulted in injuries to wolves: 2 wolves sustained injuries severe enough to result in leg amputations and 2 additional wolves died as a result of injuries sustained. Foothold traps with rubber-padded jaws and properly set snares may reduce trap-related injuries to Mexican gray wolves; however, impacts caused by trapping are overshadowed by other anthropogenic impacts (e.g., illegal shooting, non-lethal permanent removal, and vehicle collisions).

  9. [The abdominal catastrophe].

    Science.gov (United States)

    Seiler, Christian A

    2011-08-01

    Patients with an abdominal catastrophe are in urgent need of early, interdisciplinary medical help. The treatment plan should be based on medical priorities and clear leadership. First priority should be given to achieve optimal oxygenation of blood and stabilization of circulation during all treatment-phases. The sicker the patient, the less invasive the (surgical) treatment should to be, which means "damage control only". This short article describes 7 important, pragmatic rules that will help to increase the survival of a patient with an abdominal catastrophe. Preexisting morbidity and risk factors must be included in the overall risk-evaluation for every therapeutic intervention. The challenge in patients with an abdominal catastrophe is to carefully balance the therapeutic stress and the existing resistance of the individual patient. The best way to avoid abdominal disaster, however, is its prevention.

  10. The Ongoing Catastrophe

    DEFF Research Database (Denmark)

    Kublitz, Anja

    2015-01-01

    were expelled from their homeland. However, according to my interlocutors, al-Nakba never stopped, but continues in the present. To understand this phenomenon, I suggest that it is conducive to think of al-Nakba as a reverse national myth, a figure of un-becoming, which is replicated in the present. I...... argue that, unlike the spectacular catastrophes in Palestine and later in Lebanon, life in the Danish camps is characterized by minor mundane catastrophes that are each so small that they barely register or elicit a moral response, but nevertheless erode the lives of my interlocutors....

  11. Catastrophic Medical Expenditure Risk

    NARCIS (Netherlands)

    G. Flores (Gabriela); O.A. O'Donnell (Owen)

    2012-01-01

    textabstractMedical expenditure risk can pose a major threat to living standards. We derive decomposable measures of catastrophic medical expenditure risk from reference-dependent utility with loss aversion. We propose a quantile regression based method of estimating risk exposure from cross-section

  12. Catastrophic primary antiphospholipid syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dong Hun; Byun, Joo Nam [Chosun University Hospital, Gwangju (Korea, Republic of); Ryu, Sang Wan [Miraero21 Medical Center, Gwangju (Korea, Republic of)

    2006-09-15

    Catastrophic antiphospholipid syndrome (CAPLS) was diagnosed in a 64-year-old male who was admitted to our hospital with dyspnea. The clinical and radiological examinations showed pulmonary thromboembolism, and so thromboembolectomy was performed. Abdominal distension rapidly developed several days later, and the abdominal computed tomography (CT) abdominal scan revealed thrombus within the superior mesenteric artery with small bowel and gall bladder distension. Cholecystectomy and jejunoileostomy were performed, and gall bladder necrosis and small bowel infarction were confirmed. The anticardiolipin antibody was positive. Anticoagulant agents and steroids were administered, but the patient expired 4 weeks after surgery due to acute respiratory distress syndrome (ARDS). We report here on a case of catastrophic APLS with manifestations of pulmonary thromboembolism, rapidly progressing GB necrosis and bowel infarction.

  13. [Catastrophic antiphospholipid syndrome].

    Science.gov (United States)

    Wisłowska, Małgorzata

    2015-01-01

    Catastrophic antiphospholipid syndrome is the most dangerous form of the antiphospholipid syndrome, which is characterized by rapid onset of thrombosis in small vessels of many organs and intravascular coagulation, thrombocytopenia and hemolytic anemia. The syndrome develops over a short period of time with acute multi-organ failure, including kidney, respiratory, cardiovascular, central nervous system and adrenal glands, often associated with disseminated thrombotic microangiopathy. The catastrophic antiphospholipid syndrome involves three or more systems, organs and/or tissues, the development of symptoms must occur within less than one week, it is necessary to confirm the histopathological vascular occlusion in at least one organ or tissue, and laboratory confirmation of the presence of antiphospholipid antibodies in the serum on two occasions over an interval of 12 weeks. This syndrome is characterized by a high mortality despite the use of optimal treatment. Early diagnosis and aggressive treatment of patients with catastrophic antiphospholipid syndrome is essential to save the life of these patients. In the last 10 years, the mortality in this disease decreased from 50% to 30% with simultaneous treatment with anticoagulants, corticosteroids, plasmapheresis and immunoglobulins.

  14. High Altitude Platforms for Disaster Recovery: Capabilities, Strategies, and Techniques for Providing Emergency Telecommunications

    Energy Technology Data Exchange (ETDEWEB)

    Juan D. Deaton

    2008-05-01

    Natural disasters and terrorist acts have significant potential to disrupt emergency communication systems. These emergency communication networks include first-responder, cellular, landline, and emergency answering services such as 911, 112, or 999. Without these essential emergency communications capabilities, search, rescue, and recovery operations during a catastrophic event will be severely debilitated. High altitude platforms could be fitted with telecommunications equipment and used to support these critical communications missions once the catastrophic event occurs. With the ability to be continuously on station, HAPs provide excellent options for providing emergency coverage over high-risk areas before catastrophic incidents occur. HAPs could also provide enhanced 911 capabilities using either GPS or reference stations. This paper proposes potential emergency communications architecture and presents a method for estimating emergency communications systems traffic patterns for a catastrophic event.

  15. CATASTROPHIC EVENTS MODELING

    Directory of Open Access Journals (Sweden)

    Ciumas Cristina

    2013-07-01

    Full Text Available This paper presents the emergence and evolution of catastrophe models (cat models. Starting with the present context of extreme weather events and features of catastrophic risk (cat risk we’ll make a chronological illustration from a theoretical point of view of the main steps taken for building such models. In this way the importance of interdisciplinary can be observed. The first cat model considered contains three modules. For each of these indentified modules: hazard, vulnerability and financial losses a detailed overview and also an exemplification of a potential case of an earthquake that measures more than 7 on Richter scale occurring nowadays in Bucharest will be provided. The key areas exposed to earthquake in Romania will be identified. Then, based on past catastrophe data and taking into account present conditions of housing stock, insurance coverage and the population of Bucharest the impact will be quantified by determining potential losses. In order to accomplish this work we consider a scenario with data representing average values for: dwelling’s surface, location, finishing works. On each step we’ll make a reference to the earthquake on March 4 1977 to see what would happen today if a similar event occurred. The value of Bucharest housing stock will be determined taking firstly the market value, then the replacement value and ultimately the real value to quantify potential damages. Through this approach we can find the insurance coverage of potential losses and also the uncovered gap. A solution that may be taken into account by public authorities, for example by Bucharest City Hall will be offered: in case such an event occurs the impossibility of paying compensations to insured people, rebuilding infrastructure and public buildings and helping the suffering persons should be avoided. An actively public-private partnership should be created between government authorities, the Natural Disaster Insurance Pool, private

  16. Catastrophic medical expenditure risk.

    Science.gov (United States)

    Flores, Gabriela; O'Donnell, Owen

    2016-03-01

    We propose a measure of household exposure to particularly onerous medical expenses. The measure can be decomposed into the probability that medical expenditure exceeds a threshold, the loss due to predictably low consumption of other goods if it does and the further loss arising from the volatility of medical expenses above the threshold. Depending on the choice of threshold, the measure is consistent with a model of reference-dependent utility with loss aversion. Unlike the risk premium, the measure is only sensitive to particularly high expenses, and can identify households that expect to incur such expenses and would benefit from subsidised, but not actuarially fair, insurance. An empirical illustration using data from seven Asian countries demonstrates the importance of taking account of informal insurance and reveals clear differences in catastrophic medical expenditure risk across and within countries. In general, risk is higher among poorer, rural and chronically ill populations.

  17. Vitality of Neural Networks under Reoccurring Catastrophic Failures.

    Science.gov (United States)

    Sardi, Shira; Goldental, Amir; Amir, Hamutal; Vardi, Roni; Kanter, Ido

    2016-08-17

    Catastrophic failures are complete and sudden collapses in the activity of large networks such as economics, electrical power grids and computer networks, which typically require a manual recovery process. Here we experimentally show that excitatory neural networks are governed by a non-Poissonian reoccurrence of catastrophic failures, where their repetition time follows a multimodal distribution characterized by a few tenths of a second and tens of seconds timescales. The mechanism underlying the termination and reappearance of network activity is quantitatively shown here to be associated with nodal time-dependent features, neuronal plasticity, where hyperactive nodes damage the response capability of their neighbors. It presents a complementary mechanism for the emergence of Poissonian catastrophic failures from damage conductivity. The effect that hyperactive nodes degenerate their neighbors represents a type of local competition which is a common feature in the dynamics of real-world complex networks, whereas their spontaneous recoveries represent a vitality which enhances reliable functionality.

  18. Preoperative Preparation for Cardiac Surgery Facilitates Recovery, Reduces Psychological Distress, and Reduces the Incidence of Acute Postoperative Hypertension.

    Science.gov (United States)

    Anderson, Erling A.

    1987-01-01

    Cardiac surgery patients were assigned to information-only, information-plus-coping, or control preoperative preparation groups. Preoperatively, both experimental groups were significantly less anxious than were controls. Both experimental groups increased patients' belief in control over recovery. Postoperatively, experimental patients were less…

  19. Developing a Regional Recovery Framework

    Energy Technology Data Exchange (ETDEWEB)

    Lesperance, Ann M.; Olson, Jarrod; Stein, Steven L.; Clark, Rebecca; Kelly, Heather; Sheline, Jim; Tietje, Grant; Williamson, Mark; Woodcock, Jody

    2011-09-01

    Abstract A biological attack would present an unprecedented challenge for local, state, and federal agencies; the military; the private sector; and individuals on many fronts ranging from vaccination and treatment to prioritization of cleanup actions to waste disposal. To prepare the Seattle region to recover from a biological attack, the Seattle Urban Area Security Initiative (UASI) partners collaborated with military and federal agencies to develop a Regional Recovery Framework for a Biological Attack in the Seattle Urban Area. The goal was to reduce the time and resources required to recover and restore wide urban areas, military installations, and other critical infrastructure following a biological incident by providing a coordinated systems approach. Based on discussions in small workshops, tabletop exercises, and interviews with emergency response agency staff, the partners identified concepts of operation for various areas to address critical issues the region will face as recovery progresses. Key to this recovery is the recovery of the economy. Although the Framework is specific to a catastrophic, wide-area biological attack using anthrax, it was designed to be flexible and scalable so it could also serve as the recovery framework for an all-hazards approach. The Framework also served to coalesce policy questions that must be addressed for long-term recovery. These questions cover such areas as safety and health, security, financial management, waste management, legal issues, and economic development.

  20. Catastrophic Head Injuries in High School and Collegiate Sports.

    Science.gov (United States)

    Mueller, Frederick O.

    2001-01-01

    Describes the incidence of catastrophic head injuries within high school and college sports. Data from a national surveillance system indicated that a football-related fatality occurred every year except one from 1945-99, mainly related to head injuries. From 1984-99, 69 football head-related injuries resulted in permanent disability. Deaths and…

  1. Catastrophizing and perceived partner responses to pain.

    Science.gov (United States)

    Boothby, Jennifer L; Thorn, Beverly E; Overduin, Lorraine Y; Ward, L Charles

    2004-06-01

    This study examined the relationship between catastrophizing and patient-perceived partner responses to pain behaviors. The Catastrophizing subscale of the Cognitive Coping Strategy Inventory and the West Haven-Yale Multidimensional Pain Inventory were completed by 62 adult chronic pain patients. Consistent with past research, catastrophizing and patient-perceived solicitous partner behaviors were positively correlated with negative pain outcomes. The communal coping theory of catastrophizing suggests that catastrophizing might be undertaken to solicit support and empathy from others. However, catastrophizing was not related to perceived solicitous partner behavior in this study. Rather, catastrophizing was associated with perceived punishing partner responses. Implications are that catastrophizing and perceived solicitous partner behaviors are independently associated with pain and that catastrophizing may not be reinforced by empathy from significant others.

  2. Neurosurgical management for complicated catastrophic antiphospholipid syndrome.

    Science.gov (United States)

    Drazin, Doniel; Westley Phillips, H; Shirzadi, Ali; Drazin, Noam; Schievink, Wouter

    2014-04-01

    Antiphospholipid syndrome (APS) is an autoimmune condition involving arterial and venous thrombosis. An unusual APS variant, catastrophic antiphospholipid syndrome (CAPS), includes rapid multi-organ failure from widespread small vessel thrombosis. Central nervous system complications arise in one-third of CAPS patients. In rare cases, CAPS co-manifests with cerebellar hemorrhage presenting a neurosurgical emergency. We present a 65-year-old woman with CAPS-related cerebellar hematoma, co-morbid idiopathic thrombocytopenic purpura, deep vein thrombosis and altered mental status, with treatment complicated by thrombocytopenia. The patient suddenly deteriorated, secondary to a cerebellar subdural hematoma, and underwent decompression and excision of the hematoma. After recovery in the intensive care unit, she developed a new spontaneous epidural hematoma requiring additional surgery. Management of these patients is hematologically complex and often requires a multi-disciplinary team of physicians. This patient provides an important learning point for clinicians - consider CAPS when hemorrhage and thrombosis are present.

  3. THE CATASTROPHIC RISK REINSURANCE: FOREIGN EXPERIENCE

    Directory of Open Access Journals (Sweden)

    T. Tatarina

    2014-03-01

    Full Text Available The article deals with foreign experience of catastrophic risks reinsurance. The directions to ensure savings and increase capitalization of insurance companies under reinsurance protection. The necessary of catastrophic risk reinsurance in Ukraine has brought.

  4. Guidance for Catastrophic Emergency Situations Involving Asbestos

    Science.gov (United States)

    This document addresses the types of asbestos issues that may arise during catastrophic events and how EPA has addressed such issues. It replaces the Guidelines for Catastrophic Emergency Situations Involving Asbestos which was issued in 1992.

  5. Coping with ecological catastrophe: crossing major thresholds

    Directory of Open Access Journals (Sweden)

    John Cairns, Jr.

    2004-08-01

    Full Text Available The combination of human population growth and resource depletion makes catastrophes highly probable. No long-term solutions to the problems of humankind will be discovered unless sustainable use of the planet is achieved. The essential first step toward this goal is avoiding or coping with global catastrophes that result from crossing major ecological thresholds. Decreasing the number of global catastrophes will reduce the risks associated with destabilizing ecological systems, which could, in turn, destabilize societal systems. Many catastrophes will be local, regional, or national, but even these upheavals will have global consequences. Catastrophes will be the result of unsustainable practices and the misuse of technology. However, avoiding ecological catastrophes will depend on the development of eco-ethics, which is subject to progressive maturation, comments, and criticism. Some illustrative catastrophes have been selected to display some preliminary issues of eco-ethics.

  6. Addressing the Federal-State-Local Interface Issues During a Catastrophic Event Such as an Anthrax Attack

    Energy Technology Data Exchange (ETDEWEB)

    Stein, Steven L.; Lesperance, Ann M.; Upton, Jaki F.

    2010-02-01

    On October 9, 2008, federal, state and local policy makers, emergency managers, and medical and public health officials convened in Seattle, Washington, for a workshop on Addressing the Federal-State-Local Interface Issues During a Catastrophic Event Such as an Anthrax Attack. The day-long symposium was aimed at generating a dialogue about recovery and restoration through a discussion of the associated challenges that impact entire communities, including people, infrastructure, and critical systems. The Principal Federal Official (PFO) provided an overview of the role of the PFO in a catastrophic event. A high-level summary of an anthrax scenario was presented. The remainder of the day was focused on interactive discussions among federal, state and local emergency management experts in the areas of: • Decision-making, prioritization, and command and control • Public health/medical services • Community resiliency and continuity of government. Key topics and issues that resulted from discussions included: • Local representation in the Joint Field Office (JFO) • JFO transition to the Long-Term Recovery Office • Process for prioritization of needs • Process for regional coordination • Prioritization - process and federal/military intervention • Allocation of limited resources • Re-entry decision and consistency • Importance of maintaining a healthy hospital system • Need for a process to establish a consensus on when it is safe to re-enter. This needs to be across all jurisdictions including the military. • Insurance coverage for both private businesses and individuals • Interaction between the government and industry. The symposium was sponsored by the Interagency Biological Restoration Demonstration, a collaborative regional program jointly funded by the U.S. Department of Homeland Security and the U.S. Department of Defense. To aid the program’s efforts and inform the development of blueprint for recovery from a biological incident

  7. The Climate Catastrophe as Blockbuster

    DEFF Research Database (Denmark)

    Eskjær, Mikkel Fugl

    2013-01-01

    Modern disaster films constitute a specific cultural form that speaks to the anxieties of the “risk society.” This essay looks at how risks like climate change is presented and constructed in popular culture. It regards blockbuster representations as part of a wider discourse of “catastrophism......” within the realm of public climate change communication. For that reason, the essay centers on the interplay between news media and entertainment. It argues that blockbuster disaster films represent an inversion of traditional risk and disaster news....

  8. Is Geothermal Simulation a "Catastrophe"?

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, V.V.; Pinder, George F.

    1980-12-16

    All numerical simulators of geothermal reservoirs depend upon an accurate representation of the thermodynamics of steam-water systems. These relationships are required to render tractable the system of balance equations derived from the physics of flow through porous media. While it is generally recognized that the steam-water system (i.e. two phase) is not in thermodynamic equilibrium, equihbrium thermodynamics are employed in its description. In this paper, we present an alternative view based on non-equilibrium thermodynamics. The underpinnings of this approach are found in a branch of topology generally referred to as "catastrophe theory". [Thom, 1975

  9. Catastrophic Evaporation of Rocky Planets

    CERN Document Server

    Perez-Becker, Daniel

    2013-01-01

    Short-period exoplanets can have dayside surface temperatures surpassing 2000 K, hot enough to vaporize rock and drive a thermal wind. Small enough planets evaporate completely. We construct a radiative-hydrodynamic model of atmospheric escape from strongly irradiated, low-mass rocky planets, accounting for dust-gas energy exchange in the wind. Rocky planets with masses 2000 K are found to disintegrate entirely in 0.1 M_Earth/Gyr --- our model yields a present-day planet mass of < 0.02 M_Earth or less than about twice the mass of the Moon. Mass loss rates depend so strongly on planet mass that bodies can reside on close-in orbits for Gyrs with initial masses comparable to or less than that of Mercury, before entering a final short-lived phase of catastrophic mass loss (which KIC 12557548b has entered). Because this catastrophic stage lasts only up to a few percent of the planet's life, we estimate that for every object like KIC 12557548b, there should be 10--100 close-in quiescent progenitors with sub-da...

  10. Disaster risk insurance and catastrophe models in risk-prone small Caribbean islands.

    Science.gov (United States)

    Joyette, Antonio R T; Nurse, Leonard A; Pulwarty, Roger S

    2015-07-01

    Post-catastrophe recovery and financial liquidity have long challenged small Caribbean islands. These states are vulnerable to multifarious natural hazards that often cause considerable socioeconomic dislocation. Such events inflict heavy losses on businesses and households, and significantly disrupt all aspects of government operations. After Hurricane Ivan devastated the economies of some islands in September 2004-with estimated losses of as much as 200 per cent of gross domestic product in some cases-regional governments, aided by the World Bank and international donors, approved the creation of a regional catastrophe insurance scheme. This parametric-based mechanism is underpinned by derivatives-based catastrophe modelling whose outputs determine policy triggers and pay outs. Hazard models, particularly catastrophe models, are not widely accepted as yet. Despite recent advancements, major concerns have rendered them peripheral tools for many establishments. This paper reviews the region's vulnerabilities and examines constraints on the application of these models and suggests a means of improving their efficacy and acceptability.

  11. Catastrophe mechanism & classification of discontinuity behavior in thermal science (Ⅰ) --Fold catastrophe

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The mechanism of discontinuity behavior has important significance in the study of thermal science,such as fire,combustion,explosion and heat transfer.This sort of discontinuity behavior and the catastrophe caused by system nonlinearity may be equivalently classified according to the catastrophe model promulgated by catastrophe theory.Under the conditions of uniform temperature and thermal isolation,the self-ignition behavior of a Semenov System can be viewed as a result of the fold catastrophe of the system.

  12. Catastrophic Disruption of Comet ISON

    Science.gov (United States)

    Keane, Jacqueline V.; Milam, Stefanie N.; Coulson, Iain M.; Kleyna, Jan T.; Sekanina, Zdenek; Kracht, Rainer; Riesen, Timm-Emmanuel; Meech, Karen J.; Charnley, Steven B.

    2016-01-01

    We report submillimeter 450 and 850 microns dust continuum observations for comet C/2012 S1 (ISON) obtained at heliocentric distances 0.31-0.08 au prior to perihelion on 2013 November 28 (rh?=?0.0125 au). These observations reveal a rapidly varying dust environment in which the dust emission was initially point-like. As ISON approached perihelion, the continuum emission became an elongated dust column spread out over as much as 60? (greater than 10(exp 5) km in the anti-solar direction. Deconvolution of the November 28.04 850 microns image reveals numerous distinct clumps consistent with the catastrophic disruption of comet ISON, producing approximately 5.2?×?10(exp 10) kg of submillimeter-sized dust. Orbital computations suggest that the SCUBA-2 emission peak coincides with the comet's residual nucleus.

  13. Academic Training: Predicting Natural Catastrophes

    CERN Multimedia

    Françoise Benz

    2005-01-01

    2005-2006 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 12, 13, 14, 15, 16 December from 11:00 to 12:00 - Main Auditorium, bldg. 500 Predicting Natural Catastrophes E. OKAL / Northwestern University, Evanston, USA 1. Tsunamis -- Introduction Definition of phenomenon - basic properties of the waves Propagation and dispersion Interaction with coasts - Geological and societal effects Origin of tsunamis - natural sources Scientific activities in connection with tsunamis. Ideas about simulations 2. Tsunami generation The earthquake source - conventional theory The earthquake source - normal mode theory The landslide source Near-field observation - The Plafker index Far-field observation - Directivity 3. Tsunami warning General ideas - History of efforts Mantle magnitudes and TREMOR algorithms The challenge of 'tsunami earthquakes' Energy-moment ratios and slow earthquakes Implementation and the components of warning centers 4. Tsunami surveys Principles and methodologies Fifteen years of field surveys and re...

  14. Catastrophizing delays the analgesic effect of distraction.

    Science.gov (United States)

    Campbell, Claudia M; Witmer, Kenny; Simango, Mpepera; Carteret, Alene; Loggia, Marco L; Campbell, James N; Haythornthwaite, Jennifer A; Edwards, Robert R

    2010-05-01

    Behavioral analgesic techniques such as distraction reduce pain in both clinical and experimental settings. Individuals differ in the magnitude of distraction-induced analgesia, and additional study is needed to identify the factors that influence the pain relieving effects of distraction. Catastrophizing, a set of negative emotional and cognitive processes, is widely recognized to be associated with increased reports of pain. We sought to evaluate the relationship between catastrophizing and distraction analgesia. Healthy participants completed three sessions in a randomized order. In one session (Pain Alone), pain was induced by topical application of a 10% capsaicin cream and simultaneous administration of a tonic heat stimulus. In another session (Pain+Distraction), identical capsaicin+heat application procedures were followed, but subjects played video games that required a high level of attention. During both sessions, verbal ratings of pain were obtained and participants rated their degree of catastrophizing. During the other session (Distraction Alone) subjects played the video games in the absence of any pain stimulus. Pain was rated significantly lower during the distraction session compared to the "Pain Alone" session. In addition, high catastrophizers rated pain significantly higher regardless of whether the subjects were distracted. Catastrophizing did not influence the overall degree of distraction analgesia; however, early in the session high catastrophizers had little distraction analgesia, though later in the session low and high catastrophizers rated pain similarly. These results suggest that both distraction and catastrophizing have substantial effects on experimental pain in normal subjects and these variables interact as a function of time.

  15. Does catastrophic thinking enhance oesophageal pain sensitivity?

    DEFF Research Database (Denmark)

    Martel, M O; Olesen, A E; Jørgensen, D;

    2016-01-01

    that catastrophic thinking exerts an influence on oesophageal pain sensitivity, but not necessarily on the magnitude of acid-induced oesophageal sensitization. WHAT DOES THIS STUDY ADD?: Catastrophizing is associated with heightened pain sensitivity in the oesophagus. This was substantiated by assessing responses...

  16. Environmental Catastrophes Under Time-inconsistent Preferences

    NARCIS (Netherlands)

    Michielsen, T.O.

    2013-01-01

    Abstract I analyze optimal natural resource use in an intergenerational model with the risk of a catastrophe. Each generation maximizes a weighted sum of discounted utility (positive) and the probability that a catastrophe will occur at any point in the future (negative). The model generates time-in

  17. Fracto—emissions in Catastrophic Cleavage Process

    Institute of Scientific and Technical Information of China (English)

    HonglaiTAN; WeiYANG

    1996-01-01

    Fracto-emissions accompanying crack propagation are observed in the recent experiments.The energy impulses during and after fracture stimulate the fracto-emissions.Model concerning atomic scale cleavage processes is proposed to formulate a catastrophic fracure theory relevant to these phenomena.A criterion for catastrophic jump of the cleavage potential is applied to representative crystals.

  18. Lessons from Fukushima: Relocation and Recovery from Nuclear Catastrophe

    Science.gov (United States)

    2015-06-01

    than my mind with yoga , volleyball, hikes, and walks. I am thankful to the leaders at FEMA for valuing lifetime learning by supporting this program...process that weighs the costs, benefits , and tradeoffs involved with the various methods of reducing dose exposure. It discusses existing ICRP and...receiving the Chernobyl compensation benefits . Stuck in an environment with few other economic prospects, the reliance on the government payments

  19. Iodine and thyroid gland with or without nuclear catastrophe

    Directory of Open Access Journals (Sweden)

    Kovačev-Zavišić Branka

    2012-01-01

    Full Text Available Introduction. Iodine, as a trace element, is a necessary and limiting substrate for thyroid gland hormone synthesis. It is an essential element that enables the thyroid gland to produce thyroid hormones thyroxine (T4 and triiodothyronine (T3. Synthesis of Thyroid Hormones and Iodine Metabolism. Three iodine molecules are added to make triiodothyronine, and four for thyroxine - the two key hormones produced by the thyroid gland. Iodine deficiency. The proper daily amount of iodine is required for optimal thyroid function. Iodine deficiency can cause hypothyroidism, developmental brain disorders and goiter. Iodine deficiency is the single most common cause of preventable mental retardation and brain damage in the world. It also decreases child survival, causes goiters, and impairs growth and development. Iodine deficiency disorders in pregnant women cause miscarriages, stillbirths, and other complications. Children with iodine deficiency disorders can grow up stunted, apathetic, mentally retarded, and incapable of normal movements, speech or hearing. Excessive Iodine Intake. Excessive iodine intake, which can trigger autoimmune thyroid disease and dysfunction, is on the other side. Iodine use in Case of Nuclear Catastrophe. In addition to other severe consequences of radioactivity, high amount of radioactive iodine causes significant increase in incidence of thyroid gland carcinoma after some of the nuclear catastrophes (Hiroshima, Nagasaki, Chernobyl, Fukushima. The incidence of thyroid carcinoma was increased mostly in children. This paper was aimed at clarifying some of the possibilities of prevention according to the recommendations given by the World Health Organization.

  20. Catastrophic event modeling. [lithium thionyl chloride batteries

    Science.gov (United States)

    Frank, H. A.

    1981-01-01

    A mathematical model for the catastrophic failures (venting or explosion of the cell) in lithium thionyl chloride batteries is presented. The phenomenology of the various processes leading to cell failure is reviewed.

  1. Catastrophic antiphospholipid syndrome: task force report summary.

    Science.gov (United States)

    Cervera, R; Rodríguez-Pintó, I

    2014-10-01

    The Task Force on Catastrophic Antiphospholipid Syndrome (CAPS) aimed to assess the current knowledge on pathogenesis, clinical and laboratory features, diagnosis and classification, precipitating factors and treatment of CAPS. This article summarizes the main aspects of its final report.

  2. Catastrophes in Scale-Free Networks

    Institute of Scientific and Technical Information of China (English)

    ZHOU Tao; WANG Bing-Hong

    2005-01-01

    @@ An alternative model about cascading occurrences caused by perturbation is established to search the mechanism because catastrophes in networks occur. We investigate the avalanche dynamics of our model on two-dimensional Euclidean lattices and scale-free networks and find that the avalanche dynamic behaviour is sensitive to the topological structure of networks. The simulation results show that the catastrophes occur much more frequently in scale-free networks than those in Euclidean lattices, and the greatest catastrophe in scale-free networks is much more serious than that in Euclidean lattices. Furthermore, we have studied how to reduce the catastrophes'degree, and have schemed out an effective strategy, called the targeted safeguard strategy for scale-free networks.

  3. Insuring catastrophes and the role of governments

    Directory of Open Access Journals (Sweden)

    M. M. Boyer

    2013-08-01

    Full Text Available In this paper we model the cost of providing insurance coverage against natural and man-made hazards. We propose an insurance market model that explains (1 the use of reinsurance to help finance the cost of catastrophic events and (2 the implicit (or explicit presence of government entities acting as (reinsurers of last resort. Using an economic model, we show how insurance programmes should be designed to cover the losses due to a possible catastrophic natural hazard. Our results show that the optimal structure of a reinsurance programme minimizes the cost of offering insurance protection. We also show how government intervention can reduce the cost of insurance against natural catastrophes and increase policyholders' welfare. Our paper therefore offers public policy implications as to the role and presence of government as an insurer of last resort and the minimum insurance premium necessary to cover the cost of catastrophic events.

  4. Catastrophic avalanches and methods of their control

    Directory of Open Access Journals (Sweden)

    N. A. Volodicheva

    2014-01-01

    Full Text Available Definition of such phenomenon as “catastrophic avalanche” is presented in this arti-cle. Several situations with releases of catastrophic avalanches in mountains of Caucasus, Alps, and Central Asia are investigated. Materials of snow-avalanche ob-servations performed since 1960s at the Elbrus station of the Lomonosov Moscow State University (Central Caucasus were used for this work. Complex-valued measures of engineering protection demonstrating different efficiencies are consid-ered.

  5. Mindfulness, acceptance and catastrophizing in chronic pain.

    Directory of Open Access Journals (Sweden)

    Maaike J de Boer

    Full Text Available OBJECTIVES: Catastrophizing is often the primary target of the cognitive-behavioral treatment of chronic pain. Recent literature on acceptance and commitment therapy (ACT suggests an important role in the pain experience for the concepts mindfulness and acceptance. The aim of this study is to examine the influence of mindfulness and general psychological acceptance on pain-related catastrophizing in patients with chronic pain. METHODS: A cross-sectional survey was conducted, including 87 chronic pain patients from an academic outpatient pain center. RESULTS: The results show that general psychological acceptance (measured with the AAQ-II is a strong predictor of pain-related catastrophizing, independent of gender, age and pain intensity. Mindfulness (measured with the MAAS did not predict levels of pain-related catastrophizing. DISCUSSION: Acceptance of psychological experiences outside of pain itself is related to catastrophizing. Thus, acceptance seems to play a role in the pain experience and should be part of the treatment of chronic pain. The focus of the ACT treatment of chronic pain does not necessarily have to be on acceptance of pain per se, but may be aimed at acceptance of unwanted experiences in general. Mindfulness in the sense of "acting with awareness" is however not related to catastrophizing. Based on our research findings in comparisons with those of other authors, we recommend a broader conceptualization of mindfulness and the use of a multifaceted questionnaire for mindfulness instead of the unidimensional MAAS.

  6. Interactive effects of catastrophizing and suppression on responses to acute pain: a test of an appraisal x emotion regulation model.

    Science.gov (United States)

    Gilliam, Wesley; Burns, John W; Quartana, Phillip; Matsuura, Justin; Nappi, Carla; Wolff, Brandy

    2010-06-01

    We examined whether people who tend to catastrophize about pain and who also attempt to regulate negative thoughts and feelings through suppression may represent a distinct subgroup of individuals highly susceptible to pain and distress. Ninety-seven healthy normal participants underwent a 4-min ischemic pain task followed by a 2-min recovery period. Self-reported pain and distress was recorded during the task and every 20 s during recovery. Participants completed the Pain Catastrophizing Scale and the White Bear Suppression Inventory. Repeated measures multiple regression analysis (using General Linear Model procedures) revealed significant 3-way interactions such that participants scoring high on the rumination and/or helplessness subscales of the Pain Catastrophizing Scale and who scored high on the predisposition to suppress unwanted thoughts and feelings reported the greatest pain and distress during recovery. Results suggest that pain catastrophizers who attempt to regulate their substantial pain intensity and distress with maladaptive emotion regulation strategies, such as suppression, may be especially prone to experience prolonged recovery from episodes of acute pain. Thus, emotion regulation factors may represent critical variables needed to understand the full impact of catastrophic appraisals on long-term adjustment to pain.

  7. Creating catastrophes in the classroom

    Science.gov (United States)

    Andersson, Thommy

    2013-04-01

    Buildings, infrastructure and human life are being destroyed by wind and landslides. To interest and motivate pupils and to help them understand abstract knowledge, a practical experiment could be useful. These experiments will show why strong winds circulate around tropical cyclones and how fluvial geological processes affect nature and communities. The experiments are easy to set up and the equipment is not expensive. Experiment 1: Exogenic processes of water are often slow processes. This experiment will simulate water processes that can take thousands of years, in less than 40 minutes. This experiment can be presented for and understood by pupils at all levels. Letting the pupils build up the scenery will make them more curious about the course of events. During that time they will see the geomorphological genesis of landforms such as landslides, sandurs, deltas, canyons sedimentations, selective erosions. Placing small houses, bridges etc. we can lead to discussions about natural catastrophes and community planning. Material needed for the experiment is a water bucket, erosion gutter, clay (simulating rock), sand and smaller pebbles (simulating the soil), houses of "Monopoly" size and tubes. By using a table with wheels it is easy to reuse the result for other lessons. Installation of a pump can make the experiment into a closed loop system. This installation can be used for presentations outside the classroom. Experiment 2: The Coriolis Effect explains why the wind (moving objects) deflects when moving. In the northern hemisphere the deflection is clockwise and anti-clockwise in the southern hemisphere. This abstract effect is often hard for upper secondary pupils to understand. This experiment will show the effect and thus make the theory real and visible. Material needed for this experiment is a bucket, pipes, a string. At my school we had cooperation with pupils from the Industrial Technology programme who made a copper pipe construction. During the

  8. Pricing for Catastrophe Bonds Based on Expected-value Model

    Directory of Open Access Journals (Sweden)

    Junfei Chen

    2013-02-01

    Full Text Available As the catastrophes cannot be avoided and result in huge economic losses, therefore the compensation issue for catastrophe losses become an important research topic. Catastrophe bonds can effectively disperse the catastrophe risks which mainly undertaken by the government and the insurance companies currently and focus on capital more effectively in broad capital market, therefore to be an ideal catastrophe securities product. This study adopts Expectancy Theory to supplement and improve the pricing of catastrophe bonds based on Value Theory. A model of expected utility is established to determine the conditions of the expected revenue R of catastrophe bonds. The pricing model of the value function is used to get the psychological value of R,U (R-R‾, for catastrophe bonds. Finally, the psychological value is improved by the value according to expected utility and this can more accurately evaluate catastrophe bonds at a reasonable price. This research can provide decision-making for the pricing of catastrophe bonds.

  9. Incident, Action, Recovery, and Recommissioning for the 4.5-MJ Pulsed Power Supply Located at the Electromagnetic Gun Facility, Barricade C, Aberdeen Proving Ground, MD

    Science.gov (United States)

    2007-04-01

    modified and, in 2001, was placed back in operation at barricade C to operate with an electromagnetic (EM) railgun load. On 9 February 2006, a capacitor ...MJ. 15. SUBJECT TERMS pulsed power, capacitor , railgun , armature, incident 16. SECURITY CLASSIFICATION OF: 19a. NAME OF RESPONSIBLE PERSON...back in operation at barricade C to operate with an electromagnetic railgun load. The PPS consists of 18 250-kJ independently triggered modules

  10. Catastrophic Outcomes in Free Tissue Transfer: A Six-Year Review of the NSQIP Database

    Directory of Open Access Journals (Sweden)

    David W. Grant

    2014-01-01

    Full Text Available Background. No studies report robust data on the national incidence and risk factors associated with catastrophic medical outcomes following free tissue transfer. Methods. The American College of Surgeons (ACS multicenter, prospective National Surgical Quality Improvement Program (NSQIP database was used to identify patients who underwent free tissue transfer between 2006 and 2011. Multivariable logistic regression was used for statistical analysis. Results. Over the 6-year study period 2,349 patients in the NSQIP database underwent a free tissue transfer procedure. One hundred and twenty-two patients had at least one catastrophic medical outcome (5.2%. These 122 patients had 151 catastrophic medical outcomes, including 93 postoperative respiratory failure events (4.0%, 14 pulmonary emboli (0.6%, 13 septic shock events (0.5%, 12 myocardial infarctions (0.5%, 6 cardiac arrests (0.3%, 4 strokes (0.2%, 1 coma (0.0%, and 8 deaths (0.3%. Total length of hospital stay was on average 14.7 days longer for patients who suffered a catastrophic medical complication (P<0.001. Independent risk factors were identified. Conclusions. Free tissue transfer is a proven and safe technique. Catastrophic medical complications were infrequent but added significantly to length of hospital stay and patient morbidity.

  11. Evolutionary Catastrophes and the Goldilocks Problem

    CERN Document Server

    Cirkovic, Milan M

    2007-01-01

    One of the mainstays of the controversial "rare Earth" hypothesis is the "Goldilocks problem" regarding various parameters describing a habitable planet, partially involving the role of mass extinctions and other catastrophic processes in biological evolution. Usually, this is construed as support for the uniqueness of the Earth's biosphere and intelligent human life. Here I argue that this is a misconstrual and that, on the contrary, observation-selection effects, when applied to catastrophic processes, make it very difficult for us to discern whether the terrestrial biosphere and evolutionary processes which created it are exceptional in the Milky Way or not. In particular, an anthropic overconfidence bias related to the temporal asymmetry of evolutionary processes appears when we try to straightforwardly estimate catastrophic risks from the past records on Earth. This agnosticism, in turn, supports the validity and significance of practical astrobiological and SETI research.

  12. Catastrophic expenditure on medicines in Brazil

    Science.gov (United States)

    Luiza, Vera Lucia; Tavares, Noemia Urruth Leão; Oliveira, Maria Auxiliadora; Arrais, Paulo Sergio Dourado; Ramos, Luiz Roberto; Pizzol, Tatiane da Silva Dal; Mengue, Sotero Serrate; Farias, Mareni Rocha; Bertoldi, Andréa Dâmaso

    2016-01-01

    ABSTRACT OBJECTIVE To describe the magnitude of the expenditure on medicines in Brazil according to region, household size and composition in terms of residents in a situation of dependency. METHODS Population-based data from the national household survey were used, with probabilistic sample, applied between September 2013 and February 2014 in urban households. The expenditure on medicines was the main outcome of interest. The prevalence and confidence intervals (95%CI) of the outcomes were stratified according to socioeconomic classification and calculated according to the region, the number of residents dependent on income, the presence of children under five years and residents in a situation of dependency by age. RESULTS In about one of every 17 households (5.3%) catastrophic health expenditure was reported and, in 3.2%, the medicines were reported as one of the items responsible for this situation. The presence of three or more residents (3.6%) and resident in a situation of dependency (3.6%) were the ones that most reported expenditure on medicines. Southeast was the region with the lowest prevalence of expenditure on medicines. The prevalence of households with catastrophic health expenditure and on medicines in relation to the total of households showed a regressive tendency for economic classes. CONCLUSIONS Catastrophic health expenditure was present in 5.3%, and catastrophic expenditure on medicines in 3.2% of the households. Multi-person households, presence of residents in a situation of economic dependency and belonging to the class D or E had the highest proportion of catastrophic expenditure on medicines. Although the problem is important, permeated by aspects of iniquity, Brazilian policies seem to be protecting families from catastrophic expenditure on health and on medicine. PMID:27982383

  13. On a new global catastrophic ICT model

    DEFF Research Database (Denmark)

    Riaz, M. Tahir; Bhalerao, Dipashree M.; Madsen, Ole Brun

    2011-01-01

    of the world's population suffers from affordable ICT solutions and the presence of sufficient ICT infrastructure. The main goal of this paper is to create a framework to define catastrophic areas from an ICT point of view. QOS features like packet loss rate, delay, throughput and delivery ratio for 50 nodes...... coverage before and after calamities. This definition of catastrophic area from ICT point of view has no one tried before. Network parameters behavioural graphs are also important. This paper presents only behavioural part....

  14. Improving Catastrophe Modeling for Business Interruption Insurance Needs.

    Science.gov (United States)

    Rose, Adam; Huyck, Charles K

    2016-10-01

    While catastrophe (CAT) modeling of property damage is well developed, modeling of business interruption (BI) lags far behind. One reason is the crude nature of functional relationships in CAT models that translate property damage into BI. Another is that estimating BI losses is more complicated because it depends greatly on public and private decisions during recovery with respect to resilience tactics that dampen losses by using remaining resources more efficiently to maintain business function and to recover more quickly. This article proposes a framework for improving hazard loss estimation for BI insurance needs. Improved data collection that allows for analysis at the level of individual facilities within a company can improve matching the facilities with the effectiveness of individual forms of resilience, such as accessing inventories, relocating operations, and accelerating repair, and can therefore improve estimation accuracy. We then illustrate the difference this can make in a case study example of losses from a hurricane.

  15. Remembering pain after surgery: a longitudinal examination of the role of pain catastrophizing in children's and parents' recall.

    Science.gov (United States)

    Noel, Melanie; Rabbitts, Jennifer A; Tai, Gabrielle G; Palermo, Tonya M

    2015-05-01

    Children's memories for pain play a powerful role in their pain experiences. Parents' memories may also influence children's pain experiences, by influencing parent-child interactions about pain and children's cognitions and behaviors. Pain catastrophizing of children and parents has been implicated as a factor underlying memory biases; however, this has not been empirically examined. The current longitudinal study is the first to examine the role of pain catastrophizing of children and parents in the development of their pain memories after surgery. Participants were 49 youth (32 girls) aged 10 to 18 years undergoing major surgery and their parents. One week before surgery, children and parents completed measures of pain catastrophizing. Two weeks after surgery (the acute recovery period), children and parents completed measures of child pain intensity and affect. Two to 4 months after surgery, children's and parents' memories of child pain intensity and affect were elicited. Hierarchical linear regression models revealed that over and above covariates, parent catastrophizing about their child's pain (magnification, rumination) accounted for a significant portion of variance in children's affective and parents' sensory pain memories. Although parent catastrophizing had a direct effect on pain memories, mediation analyses revealed that child catastrophizing (helplessness) indirectly influenced children's and parents' pain memories through the child's postoperative pain experience. Findings highlight that aspects of catastrophic thinking about child pain before surgery are linked to distressing pain memories several months later. Although both child and parent catastrophizing influence pain memory development, parent catastrophizing is most influential to both children's and parents' evolving cognitions about child pain.

  16. The Pain Catastrophizing Scale: Development and Validation.

    Science.gov (United States)

    Sullivan, Michael J. L.; And Others

    1995-01-01

    A series of 4 studies involving 547 college students and community adults report the development of the Pain Catastrophizing Scale, its validity with clinical and nonclinical samples, and its correlation with measures of related constructs. The scale provides information about heightened responses to aversive procedures or events. (SLD)

  17. Mindfulness, Acceptance and Catastrophizing in Chronic Pain

    NARCIS (Netherlands)

    de Boer, Maaike J.; Steinhagen, Hannemike E.; Versteegen, Gerbrig J.; Struys, Michel M. R. F.; Sanderman, Robbert

    2014-01-01

    Objectives: Catastrophizing is often the primary target of the cognitive-behavioral treatment of chronic pain. Recent literature on acceptance and commitment therapy (ACT) suggests an important role in the pain experience for the concepts mindfulness and acceptance. The aim of this study is to exami

  18. Catastrophizing and Causal Beliefs in Whiplash

    NARCIS (Netherlands)

    Buitenhuis, J.; de Jong, P. J.; Jaspers, J. P. C.; Groothoff, J. W.

    2008-01-01

    Study Design. Prospective cohort study. Objective. This study investigates the role of pain catastrophizing and causal beliefs with regard to severity and persistence of neck complaints after motor vehicle accidents. Summary of Background Data. In previous research on low back pain, somatoform disor

  19. Extension of catastrophe theory to Dulac unfoldings

    NARCIS (Netherlands)

    Broer, HW; Naudot, [No Value; Roussarie, R; Dumortier, F; Broer, H; Mawhin, J; Vanderbauwhede, A; Lunel, SV

    2005-01-01

    We consider a perturbation of a Hamiltonian planar vector field. The bifurcation set of limit cycles is studied. If the vector field is defined in an annulus, limit cycles are in one to one correspondence to the zeros of a polynomial. Catastrophe theory is relevant for the study of the ensuing bifur

  20. Thoracic aortic catastrophes : towards the endovascular solution

    NARCIS (Netherlands)

    Jonker, F.H.W.

    2010-01-01

    Descending thoracic aortic catastrophes include a variety of acute pathologies of the descending thoracic aorta, which are all associated with high morbidity and mortality rates, requiring immediate intervention. For this thesis, we explored the management and outcomes of several thoracic aortic cat

  1. Recovery from Iridium-192 flakes of a radioactive source for industrial use after a radiation incident; Recuperacion de hojuelas de Iridio-192 provenientes de una fuente radiactivas de uso industrial despues de un incidente radiologico

    Energy Technology Data Exchange (ETDEWEB)

    Cruz, W.H.; Zapata, L.A., E-mail: wcruz@ipen.gob.pe, E-mail: lzapata@ipen.gob.pe [Instituto Peruano de Energia Nuclear (GRRA/IPEN), Lima (Peru). Division de Gestion de Residuos Radiactivos

    2013-07-01

    The Iridium-192 ({sup 192}Ir) is the most used and ideal for industrial radiography applications, especially in petrochemical plants and pipelines and provides better contrast sensitivity for thick (25.4 mm). This source has constructive sealed double encapsulation, the internal capsule containing stainless steel to radioactive material in the form of flakes and welded with TIG process. The radiological incident happened at a gas station fuel sales in circumstances in which there was a homogeneity test welds a tank, the flakes or Ir-192 fell off his ponytail and left scattered over an area of 2 m{sup 2}, some fell flat areas and other land so collected in lead shielding and metal container and ground source. Full recovery of the leaflets was performed at the Division of radioactive waste management (GRRA) gaining a total of 22 flakes with no radiation risk to staff performance and installation and the conclusion was reached that the misapplicaion of TIG welding was the main cause the incident. (author)

  2. Personality and temperament correlates of pain catastrophizing in young adolescents

    NARCIS (Netherlands)

    P.E.H.M. Muris (Peter); C.M.G. Meesters (Cor); M.F.C.M. Van Den Hout (Mari F. C. M.); S. Wessels (Sylvia); I.H.A. Franken (Ingmar); E.G.C. Rassin (Eric)

    2007-01-01

    textabstractPain catastrophizing is generally viewed as an important cognitive factor underlying chronic pain. The present study examined personality and temperament correlates of pain catastrophizing in a sample of young adolescents (N = 132). Participants completed the Pain Catastrophizing Scale f

  3. Recent catastrophic landslides and mitigation in China

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Increasing population density and development of mountainous terrain have brought human settlements within reach of landslide hazards.In recent years,due to the shortening of return period for severe natural events such as heavy rainfall,snowline retreating,great earthquake together with human activities,catastrophic landslides happened more frequently than before,resulting in large-scale casualties due to the increasing occurrences of rapid long-runout rock avalanches,especially in China.This paper present...

  4. Fitting the Cusp Catastrophe in R: A cusp Package Primer

    Directory of Open Access Journals (Sweden)

    Raoul P. P. P. Grasman

    2009-11-01

    Full Text Available Of the seven elementary catastrophes in catastrophe theory, the “cusp” model is the most widely applied. Most applications are however qualitative. Quantitative techniques for catastrophe modeling have been developed, but so far the limited availability of flexible software has hindered quantitative assessment. We present a package that implements and extends the method of Cobb (Cobb and Watson 1980; Cobb, Koppstein, and Chen 1983, and makes it easy to quantitatively fit and compare different cusp catastrophe models in a statistically principled way. After a short introduction to the cusp catastrophe, we demonstrate the package with two instructive examples.

  5. Prediction of Catastrophes: an experimental model

    CERN Document Server

    Peters, Randall D; Pomeau, Yves

    2012-01-01

    Catastrophes of all kinds can be roughly defined as short duration-large amplitude events following and followed by long periods of "ripening". Major earthquakes surely belong to the class of 'catastrophic' events. Because of the space-time scales involved, an experimental approach is often difficult, not to say impossible, however desirable it could be. Described in this article is a "laboratory" setup that yields data of a type that is amenable to theoretical methods of prediction. Observations are made of a critical slowing down in the noisy signal of a solder wire creeping under constant stress. This effect is shown to be a fair signal of the forthcoming catastrophe in both of two dynamical models. The first is an "abstract" model in which a time dependent quantity drifts slowly but makes quick jumps from time to time. The second is a realistic physical model for the collective motion of dislocations (the Ananthakrishna set of equations for creep). Hope thus exists that similar changes in the response to ...

  6. Performance studies – the theory of catastrophes?

    Directory of Open Access Journals (Sweden)

    Konrad Wojnowski

    2014-01-01

    Full Text Available The author of Performatyka – teoria katastrof? [“Performance studies – the theory of catastrophes?”], which is a cross-sectional investigation into performance studies, tracks the trains of thought about catastrophes in different theories of performativity, ranging from J. L. Austin’s to Jon McKenzie’s ideas. Of particular interest is how particular theoreticians integrate the term ‘catastrophe’ into their conceptual frameworks and how they evaluate it. By criticizing the approach taken by Judith Butler, who postulates “melancholic performance studies”, which brings to mind Adorno’s idea that is explicated in Minima Moralia (traurige Wissenschaft, the author tries to show how we can productively use Austin’s theses that are presented in the first chapters of his famous How to Do Things with Words. In the author’s opinion, Austin allows us to approach communicational catastrophes from a different perspective, which is often forgotten, i.e. of the functioning of contextual systems. It is shown that the tension between felicity and infelicity may be at the core of the popularity of performativity which is understood as a tool for researching contemporary cultural phenomena.

  7. Downward catastrophe of solar magnetic flux ropes

    CERN Document Server

    Zhang, Quanhao; Hu, Youqiu; Liu, Rui

    2016-01-01

    2.5D time-dependent ideal magnetohydrodynamic (MHD) models in Cartesian coordinates were used in previous studies to seek MHD equilibria involving a magnetic flux rope embedded in a bipolar, partially open background field. As demonstrated by these studies, the equilibrium solutions of the system are separated into two branches: the flux rope sticks to the photosphere for solutions at the lower branch but is suspended in the corona for those at the upper branch. Moreover, a solution originally at the lower branch jumps to the upper, as the related control parameter increases and reaches a critical value, and the associated jump is here referred to as upward catastrophe. The present paper advances these studies in three aspects. First, the magnetic field is changed to be force-free. The system still experiences an upward catastrophe with an increase in each control parameter. Secondly, under the force-free approximation, there also exists a downward catastrophe, characterized by a jump of a solution from the u...

  8. Factors that determine catastrophic expenditure for tuberculosis care: a patient survey in China

    Institute of Scientific and Technical Information of China (English)

    Chengchao Zhou; Qian Long; Jiaying Chen; Li Xiang; Qiang Li; Shenglan Tang; Fei Huang

    2016-01-01

    Background:Tuberculosis (TB) often causes catastrophic economic effects on both the individual suffering the disease and their households.A number of studies have analyzed patient and household expenditure on TB care,but there does not appear to be any that have assessed the incidence,intensity and determinants of catastrophic health expenditure (CHE) relating to TB care in China.That will be the objective of this paper.Methods:The data used for this study were derived from the baseline survey of the China Government-Gates Foundation TB Phase Ⅱ program.Our analysis included 747 TB cases.Catastrophic health expenditure for TB care was estimated using two approaches,with households defined as experiencing CHE if their annual expenditure on TB care:(a) exceeded 10 % of total household income;and (b) exceeded 40 % of their non-food expenditure (capacity to pay).Chi-square tests were used to identify associated factors and logistic regression analysis to identify the determinants of CHE.Results:The incidence of CHE was 66.8 % using the household income measure and 54.7 % using non-food expenditure (capacity to pay).An inverse association was observed between CHE rates and household income level.Significant determinants of CHE were:age,household size,employment status,health insurance status,patient income as a percentage of total household income,hospitalization and status as a minimum living security household.Factors including gender,marital status and type of TB case had no significant associations with CHE.Conclusions:Catastrophic health expenditure incidence from TB care is high in China.An integrated policy expanding the free treatment package and ensuring universal coverage,especially the height of UHC for TB patients,is needed.Financial and social protection interventions are essential for identified at-risk groups.

  9. Catastrophe theory and its application status in mechanical engineering

    Directory of Open Access Journals (Sweden)

    Jinge LIU

    Full Text Available Catastrophe theory is a kind of mathematical method which aims to apply and interpret the discontinuous phenomenon. Since its emergence, it has been widely used to explain a variety of emergent phenomena in the fields of natural science, social science, management science and some other science and technology fields. Firstly, this paper introduces the theory of catastrophe in several aspects, such as its generation, radical principle, basic characteristics and development. Secondly, it summarizes the main applications of catastrophe theory in the field of mechanical engineering, focusing on the research progress of catastrophe theory in revealing catastrophe of rotor vibration state, analyzing friction and wear failure, predicting metal fracture, and so on. Finally, it advises that later development of catastrophe theory should pay more attention to the combination of itself with other traditional nonlinear theories and methods. This paper provides a beneficial reference to guide the application of catastrophe theory in mechanical engineering and related fields for later research.

  10. Fire phenomena and nonlinearity (II). Catastrophic fire dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Z. [University of Science and Technology, Hefei (China). State Key Laboratory of Fire Science

    2000-09-01

    As one of the most important non-linear mechanisms to cause fire or exacerbate fire disaster, there is a great deal of catastrophe behaviours existing in fire processes. The main tasks of the study of catastrophic fire dynamics are: 1) analysis of the catastrophe mechanisms of discontinuity behaviours in fire systems; 2) investigation of the controlling methods of discontinuity behaviours of fire system; 3) qualitative analysis of the dynamical characteristics of fire systems; and 4) catastrophe classifying of discontinuity phenomena in fire system. The other disciplines, such as physics, chemistry, biology, geoscience, astronomy, or even social sciences (for instance, political, economics, strategics and management science), may also take the similar method to establish the corresponding branch discipline of catastrophe science and catastrophe classification method. It is pointed out that an ignition behaviour of the uniform temperature thermal explosion system under the control of radiation has cusp catastrophe mechanism. 10 refs., 3 figs.

  11. Catastrophizing and symptoms of sleep disturbances in children.

    Science.gov (United States)

    Gregory, Alice M; Noone, Deirdre M; Eley, Thalia C; Harvey, Allison G

    2010-03-01

    Catastrophizing about sleeplessness is a cognitive process associated with sleep disturbance in adults. This study aimed to (1) examine whether children catastrophize about the consequences of not sleeping; (2) define the topics that children catastrophize about; (3) assess whether there is a link between catastrophizing and sleep disturbance in children; and (4) examine whether an association between catastrophizing and sleep in children is mediated by anxiety and depression symptoms. Children completed the sleep self-report and a catastrophizing interview. Testing took place in two inner-city schools in London, UK and participants comprised 123 children aged between 8 and 10 years (49% male). Thirty-four (28%) participants reported concerns in response to the catastrophizing questionnaire. The main topics being catastrophized were concerns about sleep, physiological issues and one's own emotions. Catastrophes predicted sleep disturbance after controlling for age and sex (beta = 0.35, P anxiety and depression symptoms (beta = 0.15, P = 0.106). Symptoms of anxiety (Sobel test = 3.30, P sleep. A proportion of children catastrophized about the consequences of sleeplessness and this was associated with sleep disturbance, an association which was mediated through anxiety and depression symptoms.

  12. Repeated catastrophic valley infill following medieval earthquakes in the Nepal Himalaya.

    Science.gov (United States)

    Schwanghart, Wolfgang; Bernhardt, Anne; Stolle, Amelie; Hoelzmann, Philipp; Adhikari, Basanta R; Andermann, Christoff; Tofelde, Stefanie; Merchel, Silke; Rugel, Georg; Fort, Monique; Korup, Oliver

    2016-01-08

    Geomorphic footprints of past large Himalayan earthquakes are elusive, although they are urgently needed for gauging and predicting recovery times of seismically perturbed mountain landscapes. We present evidence of catastrophic valley infill following at least three medieval earthquakes in the Nepal Himalaya. Radiocarbon dates from peat beds, plant macrofossils, and humic silts in fine-grained tributary sediments near Pokhara, Nepal's second-largest city, match the timing of nearby M > 8 earthquakes in ~1100, 1255, and 1344 C.E. The upstream dip of tributary valley fills and x-ray fluorescence spectrometry of their provenance rule out local sources. Instead, geomorphic and sedimentary evidence is consistent with catastrophic fluvial aggradation and debris flows that had plugged several tributaries with tens of meters of calcareous sediment from a Higher Himalayan source >60 kilometers away.

  13. Science for decision making: Transmitting hazard science using catastrophic scenarios

    Science.gov (United States)

    Wein, A.

    2010-12-01

    The ShakeOut and ARkStorm scenarios are scientifically-based, multi-disciplinary efforts to describe the damages and consequences of large, but plausible, natural disasters for use in emergency management and other planning. The ShakeOut earthquake scenario, completed in 2008, posits the occurrence of a major earthquake on the southern San Andreas Fault. It was used by more than 5,000 emergency personnel in a California statewide exercise, and it underpins the Federal Emergency Management Agency’s (FEMA) Catastrophic Plan for Southern California. The ARkStorm winter storm scenario, to be completed in 2010, posits the occurrence of a statewide disaster like the storm that occurred during 1861-1862. The ARkStorm scenario will culminate with two planning summits comprised of federal and state agencies, because such an event would exceed local response and recovery capabilities. This talk will address the following questions that are critical to transmitting science for decision making with examples and observations from the two scenarios: 1) Who are the end users of the scenarios, what types of decisions can scenarios inform, and how are stakeholders engaged? 2) What forms of information and processes work best to communicate and apply the hazard science? 3) What are the challenges of using science in decision making? 4) What future directions shall we pursue? From my perspective as coordinator of economic consequences analyses for the two scenarios, I will share insights to these questions. Framing stakeholder decisions in terms of scale (e.g., household to State) and disaster phase (e.g., emergency response, recovery, and mitigation) allows us to align methods of stakeholder engagement with stakeholder decision making. For these regional-scale scenarios, the methods of engagement included stakeholder participation in project vision, scenario construction workshops, presentations, conferences, and emergency response and recovery exercises. Champions (self

  14. A unified approach of catastrophic events

    Directory of Open Access Journals (Sweden)

    S. Nikolopoulos

    2004-01-01

    Full Text Available Although there is an accumulated charge of theoretical, computational, and numerical work, like catastrophe theory, bifurcation theory, stochastic and deterministic chaos theory, there is an important feeling that these matters do not completely cover the physics of real catastrophic events. Recent studies have suggested that a large variety of complex processes, including earthquakes, heartbeats, and neuronal dynamics, exhibits statistical similarities. Here we are studying in terms of complexity and non linear techniques whether isomorphic signatures emerged indicating the transition from the normal state to the both geological and biological shocks. In the last 15 years, the study of Complex Systems has emerged as a recognized field in its own right, although a good definition of what a complex system is, actually is eluded. A basic reason for our interest in complexity is the striking similarity in behaviour close to irreversible phase transitions among systems that are otherwise quite different in nature. It is by now recognized that the pre-seismic electromagnetic time-series contain valuable information about the earthquake preparation process, which cannot be extracted without the use of important computational power, probably in connection with computer Algebra techniques. This paper presents an analysis, the aim of which is to indicate the approach of the global instability in the pre-focal area. Non-linear characteristics are studied by applying two techniques, namely the Correlation Dimension Estimation and the Approximate Entropy. These two non-linear techniques present coherent conclusions, and could cooperate with an independent fractal spectral analysis to provide a detection concerning the emergence of the nucleation phase of the impending catastrophic event. In the context of similar mathematical background, it would be interesting to augment this description of pre-seismic electromagnetic anomalies in order to cover biological

  15. Bladder Pneumatosis From a Catastrophic Vascular Event

    Directory of Open Access Journals (Sweden)

    Ian J. Cooke

    2016-09-01

    Full Text Available Air within the bladder wall, or bladder pneumatosis, is a very rare finding typically resulting from an infectious etiology, as in emphysematous cystitis (EC. However, there have been reports of bladder pneumatosis occurring without clear infectious origins. We present a case of a female patient found to have concurrent bladder and ileal pneumatosis secondary to a catastrophic vascular event. Prompt recognition of non-infectious etiologies of bladder pneumatosis is essential as this distinction may dramatically alter clinical decision-making.

  16. Catastrophic volcanic collapse: relation to hydrothermal processes.

    Science.gov (United States)

    López, D L; Williams, S N

    1993-06-18

    Catastrophic volcanic collapse, without precursory magmatic activity, is characteristic of many volcanic disasters. The extent and locations of hydrothermal discharges at Nevado del Ruiz volcano, Colombia, suggest that at many volcanoes collapse may result from the interactions between hydrothermal fluids and the volcanic edifice. Rock dissolution and hydrothermal mineral alteration, combined with physical triggers such as earth-quakes, can produce volcanic collapse. Hot spring water compositions, residence times, and flow paths through faults were used to model potential collapse at Ruiz. Caldera dimensions, deposits, and alteration mineral volumes are consistent with parameters observed at other volcanoes.

  17. Multiple Sclerosis and Catastrophic Health Expenditure in Iran

    Science.gov (United States)

    Juyani, Yaser; Hamedi, Dorsa; Hosseini Jebeli, Seyede Sedighe; Qasham, Maryam

    2016-01-01

    Background: There are many disabling medical conditions which can result in catastrophic health expenditure. Multiple Sclerosis is one of the most costly medical conditions through the world which encounter families to the catastrophic health expenditures. This study aims to investigate on what extent Multiple sclerosis patients face catastrophic costs. Method: This study was carried out in Ahvaz, Iran (2014). The study population included households that at least one of their members suffers from MS. To analyze data, Logit regression model was employed by using the default software STATA12. Results: 3.37% of families were encountered with catastrophic costs. Important variables including brand of drug, housing, income and health insurance were significantly correlated with catastrophic expenditure. Conclusions: This study suggests that although a small proportion of MS patients met the catastrophic health expenditure, mechanisms that pool risk and cost (e.g. health insurance) are required to protect them and improve financial and access equity in health care.

  18. Bankruptcy by catastrophes for major multi-nationals: stock exchange sensitivity for three catastrophes

    NARCIS (Netherlands)

    Van Gulijk, C.; Ale, B.J.M.

    2012-01-01

    This paper investigates the effect of major catastrophes have on stock exchange values for the major multi-nationals. The paper demonstrates that the Sharpe analysis is more sensitive in identifying effects than just following the daily stock values for assessing market response. It was found that m

  19. Payments for health care and its effect on catastrophe and impoverishment: experience from the transition to Universal Coverage in Thailand.

    Science.gov (United States)

    Somkotra, Tewarit; Lagrada, Leizel P

    2008-12-01

    Equitable health financing was embodied in the reform strategies of Thailand's health care system when the country moved towards implementing the Universal Coverage (UC) policy in 2001. This study aimed to measure the pattern of household out-of-pocket payments for health care and to examine the financial catastrophe and impoverishment due to such payments during the transitional period (pre- and post-Universal Coverage policy implementation) in Thailand. This study used the nationally representative Socioeconomic Surveys in 2000 (pre-UC), 2002, and 2004 (post-UC), which contained data from 24747, 34758 and 34843 individual households, respectively. The proportion of out-of-pocket payments for health care as a share of household living standards among Thai households shows a decreasing pattern during the observed period. Moreover, the incidence and intensity of catastrophic payments for health care decline from the pre-UC to post-UC period. The distribution of incidence and the intensity of catastrophic payments for health care across quintiles also indicate that the lower quintile group (1st and 2nd quintiles) incurs lower catastrophic health care payments compared to the higher quintile group. The UC policy is also effective in preventing impoverishment due to out-of-pocket payments for health care since both the poverty headcount and poverty gap decline from the pre-UC to post-UC period. This study provides important evidence that the UC policy implementation is a valuable social protection and safety net strategy that contributes to the prevention of financial catastrophe and impoverishment due to out-of-pocket payments for health care. In conclusion, the UC policy in Thailand achieves one of the goals of improving the health system through equitable health care financing by reducing financial catastrophe and impoverishment due to out-of-pocket payments for health care.

  20. Personality and temperament correlates of pain catastrophizing in young adolescents

    OpenAIRE

    Muris, Peter; Meesters, Cor; van den Hout, Mari F. C. M.; Wessels, Sylvia; Franken, Ingmar; Rassin, Eric

    2007-01-01

    textabstractPain catastrophizing is generally viewed as an important cognitive factor underlying chronic pain. The present study examined personality and temperament correlates of pain catastrophizing in a sample of young adolescents (N = 132). Participants completed the Pain Catastrophizing Scale for Children, as well as scales for measuring sensitivity of the behavioral inhibition and behavioral activation systems (BIS-BAS), and various reactive and regulative temperament traits. Results de...

  1. Mutation accumulation and the catastrophic senescence of Pacific salmon

    CERN Document Server

    Penna, T J P; Stauffer, D; Stauffer, Dietrich

    1995-01-01

    The bit-string model of biological aging is used to simulate the catastrophic senescence of Pacific Salmon. We have shown that reproduction occuring only once and at a fixed age is the only ingredient needed to explain the catastrophic senescence according the mutation accumulation theory. Several results are presented, some of them with up to 10^8 fishes, showing how the survival rates in catastrophic senescence are affected by changes in the parameters of the model.

  2. Death, Catastrophe, and the Significance of Tragedy

    Directory of Open Access Journals (Sweden)

    Jennifer Ballengee

    2014-05-01

    Full Text Available This NANO note will examine the tension between representation, memorial, and the catastrophe of death that emerges in the space of tragedy, as the problem arises in two quite different works: Oedipus at Colonus, a fairly typical fifth-century Greek tragedy, and Falling Man, Don DeLillo’s novel that, in its attempt to address the events of 9/11, reflects in form and subject matter many of Aristotle’s terms of tragic representation. It is not the intent of this note to engage with the recent proliferation of work in “performance theory.” Rather than being concerned with an imagined exchange between audience and actor, this study examines how the supplementary relationship of gesture and speech in tragedy disrupts the public/private distinction, and how this articulation effects and enables the public memorialization of death. Thus, this paper will consider the representation of death as an event whose catastrophic, and somewhat mysterious, collision of the public and the private lends it its tragic significance.

  3. Inside money, procyclical leverage, and banking catastrophes.

    Directory of Open Access Journals (Sweden)

    Charles D Brummitt

    Full Text Available We explore a model of the interaction between banks and outside investors in which the ability of banks to issue inside money (short-term liabilities believed to be convertible into currency at par can generate a collapse in asset prices and widespread bank insolvency. The banks and investors share a common belief about the future value of certain long-term assets, but they have different objective functions; changes to this common belief result in portfolio adjustments and trade. Positive belief shocks induce banks to buy risky assets from investors, and the banks finance those purchases by issuing new short-term liabilities. Negative belief shocks induce banks to sell assets in order to reduce their chance of insolvency to a tolerably low level, and they supply more assets at lower prices, which can result in multiple market-clearing prices. A sufficiently severe negative shock causes the set of equilibrium prices to contract (in a manner given by a cusp catastrophe, causing prices to plummet discontinuously and banks to become insolvent. Successive positive and negative shocks of equal magnitude do not cancel; rather, a banking catastrophe can occur even if beliefs simply return to their initial state. Capital requirements can prevent crises by curtailing the expansion of balance sheets when beliefs become more optimistic, but they can also force larger price declines. Emergency asset price supports can be understood as attempts by a central bank to coordinate expectations on an equilibrium with solvency.

  4. Inside money, procyclical leverage, and banking catastrophes.

    Science.gov (United States)

    Brummitt, Charles D; Sethi, Rajiv; Watts, Duncan J

    2014-01-01

    We explore a model of the interaction between banks and outside investors in which the ability of banks to issue inside money (short-term liabilities believed to be convertible into currency at par) can generate a collapse in asset prices and widespread bank insolvency. The banks and investors share a common belief about the future value of certain long-term assets, but they have different objective functions; changes to this common belief result in portfolio adjustments and trade. Positive belief shocks induce banks to buy risky assets from investors, and the banks finance those purchases by issuing new short-term liabilities. Negative belief shocks induce banks to sell assets in order to reduce their chance of insolvency to a tolerably low level, and they supply more assets at lower prices, which can result in multiple market-clearing prices. A sufficiently severe negative shock causes the set of equilibrium prices to contract (in a manner given by a cusp catastrophe), causing prices to plummet discontinuously and banks to become insolvent. Successive positive and negative shocks of equal magnitude do not cancel; rather, a banking catastrophe can occur even if beliefs simply return to their initial state. Capital requirements can prevent crises by curtailing the expansion of balance sheets when beliefs become more optimistic, but they can also force larger price declines. Emergency asset price supports can be understood as attempts by a central bank to coordinate expectations on an equilibrium with solvency.

  5. 5. Nonmalignant diseases after the Chernobyl catastrophe.

    Science.gov (United States)

    Yablokov, Alexey V

    2009-11-01

    This section describes the spectrum and the scale of the nonmalignant diseases that have been found among exposed populations. Adverse effects as a result of Chernobyl irradiation have been found in every group that has been studied. Brain damage has been found in individuals directly exposed--liquidators and those living in the contaminated territories, as well as in their offspring. Premature cataracts; tooth and mouth abnormalities; and blood, lymphatic, heart, lung, gastrointestinal, urologic, bone, and skin diseases afflict and impair people, young and old alike. Endocrine dysfunction, particularly thyroid disease, is far more common than might be expected, with some 1,000 cases of thyroid dysfunction for every case of thyroid cancer, a marked increase after the catastrophe. There are genetic damage and birth defects especially in children of liquidators and in children born in areas with high levels of radioisotope contamination. Immunological abnormalities and increases in viral, bacterial, and parasitic diseases are rife among individuals in the heavily contaminated areas. For more than 20 years, overall morbidity has remained high in those exposed to the irradiation released by Chernobyl. One cannot give credence to the explanation that these numbers are due solely to socioeconomic factors. The negative health consequences of the catastrophe are amply documented in this chapter and concern millions of people.

  6. A depth refugium from catastrophic coral bleaching prevents regional extinction.

    Science.gov (United States)

    Smith, Tyler B; Glynn, Peter W; Maté, Juan L; Toth, Lauren T; Gyory, Joanna

    2014-06-01

    Species intolerant of changing climate might avoid extinction within refugia buffered from extreme conditions. Refugia have been observed in the fossil record but are not well documented or understood on ecological time scales. Using a 37-year record from the eastern Pacific across the two most severe El Niño events on record (1982-1983 and 1997 1998) we show how an exceptionally thermally sensitive reef-building hydrocoral, Millepora intricata, twice survived catastrophic bleaching in a deeper-water refuge (> 11 m depth). During both events, M. intricata was extirpated across its range in shallow water, but showed recovery within several years, while two other hydrocorals without deep-water populations were driven to regional extinction. Evidence from the subfossil record in the same area showed shallow-water persistence of abundant M. intricata populations from 5000 years ago, through severe El Niño-Southern Oscillation cycles, suggesting a potential depth refugium on a millennial timescale. Our data confirm the deep refuge hypothesis for corals under thermal stress.

  7. Catastrophic antiphospholipid syndrome with concurrent thrombotic and hemorrhagic manifestations.

    Science.gov (United States)

    Rangel, M L; Alghamdi, I; Contreras, G; Harrington, T; Thomas, D B; Barisoni, L; Andrews, D; Wolf, M; Asif, A; Nayer, A

    2013-07-01

    Antiphospholipid syndrome (APS) is a distinct autoimmune prothrombotic disorder due to pathogenic autoantibodies directed against proteins that bind to phospholipids. APS is characterized by arterial and venous thrombosis and their clinical sequelae. Catastrophic antiphospholipid syndrome (CAPS) is a rare and often fatal form of APS characterized by disseminated intravascular thrombosis and ischemic injury resulting in multiorgan failure. Rarely, intravascular thrombosis in CAPS is accompanied by hemorrhagic manifestations such as diffuse alveolar hemorrhage. Here, we report a 43-year-old woman who presented with anemia, acute gastroenteritis, abnormal liver function tests, bilateral pulmonary infiltrates, and a systemic inflammatory response syndrome. The patient developed respiratory failure as a result of diffuse alveolar hemorrhage followed by acute renal failure. Laboratory tests disclosed hematuria, proteinuria, and reduced platelet count. Microbiologic tests were negative. A renal biopsy demonstrated acute thrombotic microangiopathy and extensive interstitial hemorrhage. Serologic tests disclosed antinuclear antibodies and reduced serum complement C4 concentration. Coagulation studies revealed the lupus anticoagulant and autoantibodies against cardiolipin, beta 2-glycoprotein I, and prothrombin. High-dose glucocorticoids and plasma exchange resulted in rapid resolution of pulmonary, renal, and hematological manifestations. This rare case emphasizes that CAPS can present with concurrent thrombotic and hemorrhagic manifestations. Rapid diagnosis and treatment may result in complete recovery.

  8. Catastrophic rockfalls and rockslides in the Sierra Nevada, USA

    Science.gov (United States)

    Wieczorek, Gerald F.; Evans, Stephen G.; DeGraff, Jerome V.

    2002-01-01

    Despite having a low recorded historical incidence of landsliding, the Sierra Nevada has undergone large prehistoric and historical rockfalls and rockslides that could be potentially catastrophic if they occurred today in the more densely populated parts of the region. Several large documented rockfall and rockslides have been triggered either by strong seismic shaking or long periods of unusually wet weather; however, in several instances no obvious triggering event can be identified. The glaciated topography of the higher elevations of the SierraNevada has produced many relatively small falls and slides within relatively hard, massively jointed, granitic rocks; however, where exposed to weathering for long periods after glaciation, the oversteepened rock slopes are prone to uncommonly large falls and slides. At lower elevations on the nonglaciated slopes of the Sierra Nevada, rockslides commonly occur within more weathered granitic rocks, where the strength of the rock mass is typically affected by joint weathering and alteration of the intact rock to saprolite. Historical large rock-falls and rockslides in the Sierra Nevada have created additional secondary natural hazards, including debris flows and floods from the breaching of landslide dams that can be as hazardous as the initial rockfalls and rockslides.

  9. Madame Bovary and Catastrophism: Revolving narratives

    Directory of Open Access Journals (Sweden)

    Ruth Morris

    2011-07-01

    Full Text Available Cet article relie Madame Bovary au contexte scientifique français des années 1850, en lisant le roman de Flaubert à la lumière des théories de Cuvier. Le savant français Georges Cuvier, avec nombre de ses contemporains, explique les origines du monde à l’aide de la théorie des catastrophes. D’après cette théorie, le monde est divisé en périodes très courtes ponctuées de grandes catastrophes ou, en termes cuviériens, de « révolutions » qui ont éradiqué toute vie et ont permis au monde d’être entièrement repeuplé. Une telle conception affecte l’idée même du « temps ». Cuvier pense que la formation de la Terre est relativement récente, l’époque présente n’étant vieille que de cinq mille ans. Cette compression temporelle peut être rapportée à Madame Bovary dont le « tempo » s’accroît au fur et à mesure qu’on se rapproche du dénouement. Dans la théorie des catastrophes comme dans le roman, le temps ne suit pas une ligne chronologique. Les « révolutions » viennent briser le fil continu du temps et Emma est souvent incapable de distinguer entre le passé, le présent et le futur. Les « révolutions » servent aussi à ponctuer et à perturber le cours de la vie sur Terre en produisant des événements majeurs dans l’histoire du globe. Il en est de même dans la vie d’Emma. Son existence est marquée par des événements majeurs, comme le bal, qui créent un éclatement et une fragmentation de la temporalité, comme dans la théorie de Cuvier. Je défendrai aussi l’idée d’un lien entre la soudaineté et la violence des « révolutions » et les crises nerveuses d’Emma, qui surviennent brusquement et relèvent de l’hystérie. La conception cuviérienne de la temporalité doit enfin être envisagée au regard des théories de l’évolution, ce qui implique de réévaluer les notions d’adaptation, d’hérédité et de mort dans le roman de Flaubert.This paper locates Madame

  10. Recovery Swaps

    OpenAIRE

    Berd, Arthur M.

    2010-01-01

    We derive an arbitrage free relationship between recovery swap rates, digital default swap spreads and conventional CDS spreads, and argue that the fair forward recovery rate used in recovery swaps must contain a convexity premium over the expected recovery value.

  11. Catastrophic Consequences of Kicking the Chameleon

    CERN Document Server

    Erickcek, Adrienne L; Burrage, Clare; Huang, Zhiqi

    2013-01-01

    The physics of the "dark energy" that drives the current cosmological acceleration remains mysterious, and the dark sector may involve new light dynamical fields. If these light scalars couple to matter, a screening mechanism must prevent them from mediating an unacceptably strong fifth force locally. Here we consider a concrete example: the chameleon mechanism. We show that the same coupling between the chameleon field and matter employed by the screening mechanism also has catastrophic consequences for the chameleon during the Universe's first minutes. The chameleon couples to the trace of the stress-energy tensor, which is temporarily non-zero in a radiation-dominated universe whenever a particle species becomes non-relativistic. These "kicks" impart a significant velocity to the chameleon field, causing its effective mass to vary non-adiabatically and resulting in the copious production of quantum fluctuations. Dissipative effects strongly modify the background evolution of the chameleon field, invalidati...

  12. Simple scaling of catastrophic landslide dynamics.

    Science.gov (United States)

    Ekström, Göran; Stark, Colin P

    2013-03-22

    Catastrophic landslides involve the acceleration and deceleration of millions of tons of rock and debris in response to the forces of gravity and dissipation. Their unpredictability and frequent location in remote areas have made observations of their dynamics rare. Through real-time detection and inverse modeling of teleseismic data, we show that landslide dynamics are primarily determined by the length scale of the source mass. When combined with geometric constraints from satellite imagery, the seismically determined landslide force histories yield estimates of landslide duration, momenta, potential energy loss, mass, and runout trajectory. Measurements of these dynamical properties for 29 teleseismogenic landslides are consistent with a simple acceleration model in which height drop and rupture depth scale with the length of the failing slope.

  13. Grasshopper Population Ecology: Catastrophe, Criticality, and Critique

    Directory of Open Access Journals (Sweden)

    Jeffrey A. Lockwood

    2008-06-01

    Full Text Available Grasshopper population dynamics are an important part of the North American rangeland ecosystem and an important factor in the economies that derive from the rangeland. Outbreak dynamics have plagued management strategies in the rangeland, and attempts to find simple, linear and mechanistic solutions to both understanding and predicting the dynamics have proved fruitless. These efforts to ground theory in a correspondence with the “real” world, including whether the population dynamics are ultimately density dependent or density independent, have generated abundant heat but little light. We suggest that a pragmatic approach, in which theories are taken to be “tools” rather than competing claims of truth, has greater promise to move ecological research in a constructive direction. Two recent non-linear approaches exploiting the tools of complexity science provide insights relevant to explaining and forecasting population dynamics. Observation and data collection were used to structure models derived from catastrophe theory and self-organized criticality. These models indicate that nonlinear processes are important in the dynamics of the outbreaks. And the conceptual structures of these approaches provide clear, albeit constrained or contingent, implications for pest managers. We show that, although these two frameworks, catastrophe theory and self-organized criticality, are very different, the frequency distributions of time series from both systems result in power law relationships. Further, we show that a simple lattice-based model, similar to SOC but structured on the biology of the grasshoppers gives a spatial time series similar to data over a 50-year span and the frequency distribution is also a power law relationship. This demonstration exemplifies how a “both–and” rather than an “either–or” approach to ecological modeling, in which the useful elements of particular theories or conceptual structures are extracted, may

  14. Cell death by mitotic catastrophe: a molecular definition

    NARCIS (Netherlands)

    Castedo, M.; Perfettini, J.-L.; Roumier, T.; Andreau, K.; Medema, R.H.; Kroemer, G.

    2004-01-01

    The current literature is devoid of a clearcut definition of mitotic catastrophe, a type of cell death that occurs during mitosis. Here, we propose that mitotic catastrophe results from a combination of deficient cell-cycle checkpoints (in particular the DNA structure checkpoints and the spindle ass

  15. Catastrophe, gender and urban experience 1648-1920

    DEFF Research Database (Denmark)

    Employing a broad definition of catastrophe, this book examines how urban communities conceived, adapted to and were transformed by catastrophes. Competing views of gender figure in the telling and retelling of these trag- edies, which are mediated by myth and memory. This is a nuanced account...

  16. Purchase of Catastrophe Insurance by Dutch Dairy and Arable Farmers

    NARCIS (Netherlands)

    Ogurtsov, V.; Asseldonk, van M.A.P.M.; Huirne, R.B.M.

    2009-01-01

    This article analyzed the impact of risk perception, risk attitude, and other farmer personal and farm characteristics on the actual purchase of catastrophe insurance by Dutch dairy and arable farmers. The specific catastrophe insurance types considered were hail–fire–storm insurance for buildings,

  17. 'Performative narrativity': Palestinian identity and the performance of catastrophe

    NARCIS (Netherlands)

    Saloul, I.

    2008-01-01

    The day Israel annually celebrates as its "Day of Independence" Palestinians commemorate as their day of catastrophe (al-nakba). To most Palestinians, the catastrophic loss of Palestine in 1948 represents the climactic formative event of their lives. In the aftermath of this loss, the Palestinian so

  18. Catastrophic healthcare expenditure - drivers and protection: the Portuguese case.

    Science.gov (United States)

    Kronenberg, Christoph; Barros, Pedro Pita

    2014-03-01

    The objective of this paper is to assess the extent of catastrophic healthcare expenditure, which can lead to impoverishment, even in a country with a National Health Service, such as Portugal. The level of catastrophic healthcare expenditure will be identified before the determinants of these catastrophic payments are analyzed. Afterwards, the effects of existing exemptions to copayments in health care use will be tested and the relationship between catastrophe and impoverishment will be discussed. Catastrophe is calculated from the Portuguese Household Budget Surveys of 2000 and 2005, and then analyzed using logistic regression models. The results show that catastrophe due to healthcare out-of-pocket payments are a sizeable issue in Portugal. Exemptions from out-of-pocket expenses for medical care should be created to prevent vulnerable groups from facing catastrophic healthcare spending. These vulnerable groups include children, people with disabilities and individuals suffering from chronic conditions. Disability proxies offer straightforward policy options for an exemption for the elderly with recognized disabilities. An exemption of retired people with disabilities is therefore recommended to policymakers as it targets a vulnerable group with high risk of facing catastrophic healthcare expenditure.

  19. Psychological resilience predicts decreases in pain catastrophizing through positive emotions.

    Science.gov (United States)

    Ong, Anthony D; Zautra, Alex J; Reid, M Carrington

    2010-09-01

    The study used a daily process design to examine the role of psychological resilience and positive emotions in the day-to-day experience of pain catastrophizing. A sample of 95 men and women with chronic pain completed initial assessments of neuroticism, psychological resilience, and demographic data, and then completed short diaries regarding pain intensity, pain catastrophizing, and positive and negative emotions every day for 14 consecutive days. Multilevel modeling analyses indicated that independent of level of neuroticism, negative emotions, pain intensity, income, and age, high-resilient individuals reported greater positive emotions and exhibited lower day-to-day pain catastrophizing compared with low-resilient individuals. Mediation analyses revealed that psychologically resilient individuals rebound from daily pain catastrophizing through experiences of positive emotion. Implications for research on psychological resilience, pain catastrophizing, and positive emotions are discussed.

  20. Grey forewarning and prediction for mine water inflowing catastrophe periods

    Institute of Scientific and Technical Information of China (English)

    MA Qi-hua; CAO Jian-jun

    2007-01-01

    Based on the theory of grey system, established GM (1, 1) grey catastrophe predict model for the first time in order to forecast the catastrophe periods of mine water inflowing (not the volume of water inflowing). After establishing the grey predict system of the catastrophe regularity of 10 month-average volume of water inflowing, the grey forewarning for mine water inflowing catastrophe periods was established which was used to analyze water disaster in -400 meter level of Wennan Colliery. Based on residual analysis,it shows that the result of grey predict system is almost close to the actual value. And the scene actual result also shows the reliability of prediction. Both the theoretical analysis and the scene actual result indicate feasibility and reliability of the method of grey catastrophe predict system.

  1. Manipulation of pain catastrophizing: An experimental study of healthy participants

    Directory of Open Access Journals (Sweden)

    Joel E Bialosky

    2008-11-01

    Full Text Available Joel E Bialosky1*, Adam T Hirsh2,3, Michael E Robinson2,3, Steven Z George1,3*1Department of Physical Therapy; 2Department of Clinical and Health Psychology; 3Center for Pain Research and Behavioral Health, University of Florida, Gainesville, Florida, USAAbstract: Pain catastrophizing is associated with the pain experience; however, causation has not been established. Studies which specifically manipulate catastrophizing are necessary to establish causation. The present study enrolled 100 healthy individuals. Participants were randomly assigned to repeat a positive, neutral, or one of three catastrophizing statements during a cold pressor task (CPT. Outcome measures of pain tolerance and pain intensity were recorded. No change was noted in catastrophizing immediately following the CPT (F(1,84 = 0.10, p = 0.75, partial η2 < 0.01 independent of group assignment (F(4,84 = 0.78, p = 0.54, partial η2 = 0.04. Pain tolerance (F(4 = 0.67, p = 0.62, partial η2 = 0.03 and pain intensity (F(4 = 0.73, p = 0.58, partial η2 = 0.03 did not differ by group. This study suggests catastrophizing may be difficult to manipulate through experimental pain procedures and repetition of specific catastrophizing statements was not sufficient to change levels of catastrophizing. Additionally, pain tolerance and pain intensity did not differ by group assignment. This study has implications for future studies attempting to experimentally manipulate pain catastrophizing.Keywords: pain, catastrophizing, experimental, cold pressor task, pain catastrophizing scale

  2. [Critical incidents].

    Science.gov (United States)

    Scheidegger, D

    2005-03-01

    In medicine real severe mishaps are rare. On the other hand critical incidents are frequent. Anonymous critical incident reporting systems allow us to learn from these mishaps. This learning process will make our daily clinical work safer Unfortunately, before these systems can be used efficiently our professional culture has to be changed. Everyone in medicine has to admit that errors do occur to see the need for an open discussion. If we really want to learn from errors, we cannot punish the individual, who reported his or her mistake. The interest is primarily in what has happened and why it has happened and not who has committed this mistake. The cause for critical incidents in medicine is in over 80% the human factor Poor communication, work under enormous stress, conflicts and hierarchies are the main cause. This has been known for many years, therefore have already 15 years ago high-tech industries, like e.g. aviation, started to invest in special courses on team training. Medicine is a typical profession were until now only the individual performance decided about the professional career Communication, conflict management, stress management, decision making, risk management, team and team resource management were subjects that have never been taught during our preor postgraduate education. These points are the most important ones for an optimal teamwork. A multimodular course designed together with Swissair (Human Aspect Development medical, HADmedical) helps to cover, as in aviation, the soft factor and behavioural education in medicine and to prepare professionals in health care to work as a real team.

  3. Empirical Bayes Credibility Models for Economic Catastrophic Losses by Regions

    Directory of Open Access Journals (Sweden)

    Jindrová Pavla

    2017-01-01

    Full Text Available Catastrophic events affect various regions of the world with increasing frequency and intensity. The number of catastrophic events and the amount of economic losses is varying in different world regions. Part of these losses is covered by insurance. Catastrophe events in last years are associated with increases in premiums for some lines of business. The article focus on estimating the amount of net premiums that would be needed to cover the total or insured catastrophic losses in different world regions using Bühlmann and Bühlmann-Straub empirical credibility models based on data from Sigma Swiss Re 2010-2016. The empirical credibility models have been developed to estimate insurance premiums for short term insurance contracts using two ingredients: past data from the risk itself and collateral data from other sources considered to be relevant. In this article we deal with application of these models based on the real data about number of catastrophic events and about the total economic and insured catastrophe losses in seven regions of the world in time period 2009-2015. Estimated credible premiums by world regions provide information how much money in the monitored regions will be need to cover total and insured catastrophic losses in next year.

  4. The relation between catastrophizing and the communication of pain experience.

    Science.gov (United States)

    Sullivan, M J L; Martel, M O; Tripp, D; Savard, A; Crombez, G

    2006-06-01

    The Communal Coping Model of pain catastrophizing proposes that pain catastrophizers enact pain behaviors in order to solicit support or empathy from their social environment. By this account, pain catastrophizers might be expected to engage in behavior aimed at maximizing the probability that their pain will be perceived by others in their social environment. To test this prediction, 40 undergraduates were videotaped during a cold pressor procedure. A separate sample of 20 (10 men, 10 women) undergraduates were asked to view the video sequences and infer the pain ratings of the cold pressor participants. Correlational analyses revealed that higher levels of pain catastrophizing of the cold pressor participants were associated with observer inferences of more intense pain, r=.39, ppain catastrophizing and observer inferences of pain intensity was mediated by the cold pressor participants' pain behavior. Although pain catastrophizing was associated with observers' inferences of more intense pain, cold pressor participants' level of pain catastrophizing was not associated with observers' accuracy in inferring self-reported pain. Implications of the findings for theory and clinical practice are addressed.

  5. Catastrophic Cracking Courtesy of Quiescent Cavitation

    CERN Document Server

    Daily, D Jesse; Thomson, Scott L; Truscott, Tadd T

    2012-01-01

    A popular party trick is to fill a glass bottle with water and hit the top of the bottle with an open hand, causing the bottom of the bottle to break open. We investigate the source of the catastrophic cracking through the use of high-speed video and an accelerometer attached to the bottom of a glass bottle. Upon closer inspection, it is obvious that the acceleration caused by hitting the top of the bottle is followed by the formation of bubbles near the bottom. The nearly instantaneous acceleration creates an area of low pressure on the bottom of the bottle where cavitation bubbles form. Moments later, the cavitation bubbles collapse at roughly 10 times the speed of formation, causing the bottle to break. The accelerometer data shows that the bottle is broken after the bubbles collapse and that the magnitude of the bubble collapse is greater than the initial impact. The fluid dynamics video highlights that this trick will not work if the bottle is empty nor if it is filled with a carbonated fluid because the...

  6. Avoiding Environmental Catastrophes: Varieties of Principled Precaution

    Directory of Open Access Journals (Sweden)

    Alan R. Johnson

    2012-09-01

    Full Text Available The precautionary principle is often proposed as a guide to action in environmental management or risk assessment, and has been incorporated in various legal and regulatory contexts. For many, it reflects the common sense notion of being safe rather than sorry, but it has attracted numerous critics. At times, proponents and critics talk at cross purposes, due to the multiplicity of ways the precautionary principle has been formulated. The approach taken here is to examine four general varieties of precaution, relating each to arguments made in various contexts by others. First, I examine the parallel between the precautionary principle and an argument referred to as Pascal's wager. Critics are right to dismiss versions of the precautionary principle that follow the logic of Pascal's wager, because that argument requires assumption of an infinite catastrophe, which is seldom the case in environmental decisions. Second, I explore precaution viewed as an instance of the phenomenon of ambiguity aversion as described by Daniel Ellsberg. Third, I evaluate precautionary perspectives on our duties to future generations, drawing inspiration from the views of Gifford Pinchot. Fourth, I consider the precautionary principle as an instance of Aldo Leopold's notion of intelligent tinkering. Although controversy persists, I find that a legitimate theoretical foundation exists to implement Ellsbergian, Pinchotian and Leopoldean varieties of precaution in environmental decision making. Additionally, I remark on the role of adaptive management and maintaining resilience in ecological and social systems as an approach to implementing the precautionary principle.

  7. The Potential for Space Intervention in Global Catastrophes

    Science.gov (United States)

    Hempsell, M.

    There is a growing understanding of the risks facing mankind of global catastrophe, which is defined as an event that kills a quarter the world population and risks destruction of organised society. Such catastrophes can be triggered by either naturally occurring, or arthropogenic, initiating events. And history shows that catastrophes with a natural origin do occur, with a mean separation time of around 1000 years. Anthropogenic initiated events are a recent possibility resulting from an expansion of technology capabilities, economic activity and population and, while they clearly significantly increase the total risk level above the natural background, it is more difficult to determine quantitatively by how much. Some initiating events and be directly tackled by an appropriate space capability. For example intercepting Near Earth Object before collision, or using Solar Power Satellites to eliminating carbon dioxide production in the power generation process to which many attribute global warming. Obviously prevention is the preferred option and so, not surprisingly, these particular uses of space as a means of preventing global catastrophe have received considerable attention. However space capability has a much wider potential for intervention in global catastrophes, even in those where the initiating event itself cannot be prevented. Previous work highlighting the risks through consideration of historic catastrophes has identified that global catastrophes have a complex structure with the initiating event triggering chains of vectors, which in turn trigger death causing agents. The work also highlighted that the vectors and agents during a catastrophe are similar regardless of the initiating event. This opens the possibility that space systems capable of addressing generic vectors and agents on a global scale can help deal with any global catastrophe regardless of its cause. The paper lists known (and credible) components to global catastrophes and highlight

  8. Risk Measure and Premium Distribution on Catastrophe Reinsurance

    Institute of Scientific and Technical Information of China (English)

    XUN LI; WANG DE-HUI

    2012-01-01

    In this paper,we propose a new risk measure which is based on the Orlicz premium principle to characterize catastrophe risk premium.The intention is to develop a formulation strategy for Catastrophe Fund.The logarithm equivalent form of reinsurance premium is regarded as the retention of reinsurer,and the differential earnings between the reinsurance premium and the reinsurer's retention is accumulated as a part of Catastrophe Fund.We demonstrate that the aforementioned risk measure has some good properties,which are further confirmed by numerical simulations in R environment.

  9. How effective incident management retains market share.

    Science.gov (United States)

    Enright, Courtenay

    2012-01-01

    This paper discusses the need for business continuity practitioners to make incident management a focal element of their programme. Particularly during the first few minutes and hours of a business disruption, an established incident management methodology is not only key to achieving a successful, coordinated recovery, but it can play an even more important role in maintaining customer confidence following a disruption or crisis.

  10. Gradient catastrophe and Fermi-edge resonances in Fermi gas.

    Science.gov (United States)

    Bettelheim, E; Kaplan, Y; Wiegmann, P

    2011-04-22

    Any smooth spatial disturbance of a degenerate Fermi gas inevitably becomes sharp. This phenomenon, called the gradient catastrophe, causes the breakdown of a Fermi sea to multiconnected components characterized by multiple Fermi points. We argue that the gradient catastrophe can be probed through a Fermi-edge singularity measurement. In the regime of the gradient catastrophe the Fermi-edge singularity problem becomes a nonequilibrium and nonstationary phenomenon. We show that the gradient catastrophe transforms the single-peaked Fermi-edge singularity of the tunneling (or absorption) spectrum to a sequence of multiple asymmetric singular resonances. An extension of the bosonic representation of the electronic operator to nonequilibrium states captures the singular behavior of the resonances.

  11. Systematic care management: a comprehensive approach to catastrophic injury management applied to a catastrophic burn injury population--clinical, utilization, economic, and outcome data in support of the model.

    Science.gov (United States)

    Kucan, John; Bryant, Ernest; Dimick, Alan; Sundance, Paula; Cope, Nathan; Richards, Reginald; Anderson, Chris

    2010-01-01

    The new standard for successful burn care encompasses both patient survival and the burn patient's long-term quality of life. To provide optimal long-term recovery from catastrophic injuries, including catastrophic burns, an outcome-based model using a new technology called systematic care management (SCM) has been developed. SCM provides a highly organized system of management throughout the spectrum of care that provides access to outcome data, consistent oversight, broader access to expert providers, appropriate allocation of resources, and greater understanding of total costs. Data from a population of 209 workers' compensation catastrophic burn cases with a mean TBSA of 27.9% who were managed under the SCM model of care were analyzed. The data include treatment type, cost, return to work, and outcomes achieved. Mean duration of management to achieve all guaranteed outcomes was 20 months. Of the 209 injured workers, 152 (72.7%) achieved sufficient recovery to be released to return to work, of which 97 (46.8%) were both released and competitively employed. Assessment of 10 domains of functional independence indicated that 47.2% of injured workers required total assistance at initiation of SCM. However, at termination of SCM, 84% of those injured workers were fully independent in the 10 functional activities. When compared with other burn research outcome data, the results support the value of the SCM model of care.

  12. UKRAINIAN EVENTS AS HISTORICAL, INTERNATIONAL CATASTROPHE

    Directory of Open Access Journals (Sweden)

    V. V. Kasyanov

    2016-01-01

    Full Text Available In the scientific article fully examines current events in Ukraine in 2014-2015. The author believes that the causal and comparative historical analysis of the current Ukrainian crisis allows characterizing it as a major historical and ethnic catastrophe on a global scale after the collapse of the USSR in 1991. Obvious microand macroeffects inevitably impact on the history of relations between Ukrainian and Russian brotherly nations, lead (and has led to freeze their contacts, projects and links. It causes a feeling of well-founded anxiety for the fate of not only bilateral relations between Ukraine and Russia and the state of Post-Soviet space, but also for the development of all Slavic ethnic groups in the world. According to the author, it is necessary to review quickly realized Ukrainian direction of Russian state policy. It is necessary, as quickly as possible to get away from officiously promotional activities, technologies and techniques of information war and bring aid all the diversity of cultural cooperation. It is only a means of soft power, understood by us in the manner of the approach of its founder, American political scientist Joseph Nye, are able to restore the broken trust and interaction structures. Only the culture, and more specifically it such areas as language, traditions, generation feats, faith, can gradually normalize, and then to improve the bilateral relations, the each other perception, to restore a sense of respect, friendship and mutual assistance between Ukraine and Russia. It is obvious that bilateral cultural project able to change the existing negative situation.

  13. Catastrophic antiphospholipid antibody syndrome in a child with thrombotic microangiopathy.

    Science.gov (United States)

    Prasad, N; Bhadauria, D; Agarwal, N; Gupta, A; Gupta, P; Jain, M; Lal, H

    2012-07-01

    Thrombotic microangiopathic hemolytic anemia (TMHA) is not uncommon in clinical nephrology practice while antiphospholipid syndrome (APS) is uncommon. Although less than 1% of patients with APS develop catastrophic APS (CAPS), its potential lethal outcome because of thrombosis in multiple organs and subsequent multiorgan failure emphasizes its importance in nephrology practice. Here is a case of catastrophic APS in a 7-year-old girl, who presented to us with TMHA associated with antiphospholipid antibodies and subsequently died because of CAPS.

  14. Pain frequency moderates the relationship between pain catastrophizing and pain

    OpenAIRE

    2014-01-01

    Background: Pain frequency has been shown to influence sensitization, psychological distress, and pain modulation. The present study examined if pain frequency moderates the relationship between pain catastrophizing and pain. Method: A non-clinical (247 students) and a clinical (223 pain patients) sample completed the Danish versions of the Pain Catastrophizing Scale (PCS), Beck Depression Inventory, and the State Trait Anxiety Inventory and rated pain intensity, unpleasantness and frequen...

  15. Pain frequency moderates the relationship between pain catastrophizing and pain

    OpenAIRE

    2014-01-01

    Background Pain frequency has been shown to influence sensitization, psychological distress and pain modulation. The present study examined if pain frequency moderates the relationship between pain catastrophizing and pain. Method A non-clinical (247 students) and a clinical (223 pain patients) sample completed the Danish versions of the Pain Catastrophizing Scale, Beck Depression Inventory and the State Trait Anxiety Inventory and rated pain intensity, unpleasantness and frequency Results In...

  16. Pain Catastrophizing Correlates with Early Mild Traumatic Brain Injury Outcome

    Science.gov (United States)

    Chaput, Geneviève; Lajoie, Susanne P.; Naismith, Laura M.; Lavigne, Gilles

    2016-01-01

    Background. Identifying which patients are most likely to be at risk of chronic pain and other postconcussion symptoms following mild traumatic brain injury (MTBI) is a difficult clinical challenge. Objectives. To examine the relationship between pain catastrophizing, defined as the exaggerated negative appraisal of a pain experience, and early MTBI outcome. Methods. This cross-sectional design included 58 patients diagnosed with a MTBI. In addition to medical chart review, postconcussion symptoms were assessed by self-report at 1 month (Time 1) and 8 weeks (Time 2) after MTBI. Pain severity, psychological distress, level of functionality, and pain catastrophizing were measured by self-report at Time 2. Results. The pain catastrophizing subscales of rumination, magnification, and helplessness were significantly correlated with pain severity (r = .31 to .44), number of postconcussion symptoms reported (r = .35 to .45), psychological distress (r = .57 to .67), and level of functionality (r = −.43 to −.29). Pain catastrophizing scores were significantly higher for patients deemed to be at high risk of postconcussion syndrome (6 or more symptoms reported at both Time 1 and Time 2). Conclusions. Higher levels of pain catastrophizing were related to adverse early MTBI outcomes. The early detection of pain catastrophizing may facilitate goal-oriented interventions to prevent or minimize the development of chronic pain and other postconcussion symptoms. PMID:27445604

  17. Pain Catastrophizing Correlates with Early Mild Traumatic Brain Injury Outcome

    Directory of Open Access Journals (Sweden)

    Geneviève Chaput

    2016-01-01

    Full Text Available Background. Identifying which patients are most likely to be at risk of chronic pain and other postconcussion symptoms following mild traumatic brain injury (MTBI is a difficult clinical challenge. Objectives. To examine the relationship between pain catastrophizing, defined as the exaggerated negative appraisal of a pain experience, and early MTBI outcome. Methods. This cross-sectional design included 58 patients diagnosed with a MTBI. In addition to medical chart review, postconcussion symptoms were assessed by self-report at 1 month (Time 1 and 8 weeks (Time 2 after MTBI. Pain severity, psychological distress, level of functionality, and pain catastrophizing were measured by self-report at Time 2. Results. The pain catastrophizing subscales of rumination, magnification, and helplessness were significantly correlated with pain severity (r=.31 to .44, number of postconcussion symptoms reported (r=.35 to .45, psychological distress (r=.57 to .67, and level of functionality (r=-.43 to -.29. Pain catastrophizing scores were significantly higher for patients deemed to be at high risk of postconcussion syndrome (6 or more symptoms reported at both Time 1 and Time 2. Conclusions. Higher levels of pain catastrophizing were related to adverse early MTBI outcomes. The early detection of pain catastrophizing may facilitate goal-oriented interventions to prevent or minimize the development of chronic pain and other postconcussion symptoms.

  18. Finding the "Sweet Spot" for Catastrophic Incident Search and Rescue

    Science.gov (United States)

    2009-09-01

    38 Figure 3. 2008 Multiagency Communications Centers for RNC and DNC ..................105 Figure 4. A JAGCC Will Facilitate Coordination and...and Democratic National Conventions ( DNC ). Approximately 70 agencies were represented in the RNC and 63 in the DNC respective MACCs in 2008 (Gottfried...2008) as presented in Figure 3. Figure 3. 2008 Multiagency Communications Centers for RNC and DNC The MACC is a good example of a field

  19. Assessing the Utility of Work Team Theory in a Unified Command Environment at Catastrophic Incidents

    Science.gov (United States)

    2005-03-01

    Key to Unified Command. Fire Management Notes, Vol. 49, Number 1; (1988), pp. 8-9. North, Robert C.; Koch, Jr., Howard E.; Zinnes , Dina A., The...announced its intent to issue a tentative interim agreement this 98 North, Robert C.; Koch, Jr., Howard ...E.; Zinnes , Dina A. “The Integrative Functions of Conflict,” The Journal of Conflict Resolution, Vol. 4, No. 3, (Sept., 1960), 355-374 (355). 64

  20. Catastrophic antiphospholipid syndrome in obstetric practice

    Directory of Open Access Journals (Sweden)

    Валерий Николаевич Запорожан

    2015-05-01

    Full Text Available Thus, the Catastrophic antiphospholipid syndrome (CAPS is much more common than has been assumed until now, in all patients the authors strongly recommend screening for AFA. Furthermore, eclampsia, HELLP-syndrome premature detachment of normally located placentae (PDNSP can develop in the presence of other defects of hemostasis, in particular in mutation FV Leiden, MTHFR C677T, deficiency of protein C (PC, protein S (PS. The combination of acquired thrombophilia due to APS, with genetic defects worsen hemostasis during the pathological process leading to the development of thrombotic complications. Perhaps a combination of hereditary thrombophilia and APS creates a favorable environment in which, under certain conditions, possible decompensation of the hemostatic system and the development of CAPS. Patients with APS constitute a group of very high risk of thromboembolic complications in the perioperative period. Even a minimally invasive intervention (biopsy, curettage, tooth extraction may trigger the development of CAPS. Thus, according to Erkan et al. (2003, 40% of patients develop CAPS was provoked by surgery. The main reasons for the development of thrombotic complications in connection with surgical intervention is the damage to the vessel wall, blood stasis and the abolition of indirect anticoagulants. In the study on the presence of genetic thrombophilia was found heterozygous form of FV Leiden mutation and homozygous mutation of MTHFR C677T. He was diagnosed with pregnancy 14 weeks, APS, mixed form of thrombophilia (a combination of acquisitions and multigenic thrombophilia, hyperhomocysteinemia, weighed down by obstetric and somatic history.It is very urgent and important problem remains diagnosis CAPS, which is inconceivable without the determination of AFA. The latter should be mandatory for all pregnant women with preeclampsia habitual miscarriage, Premature detachment of normally situated placenta (PDNSP, genital herpes history

  1. Catastrophic Antiphospholipid Syndrome Presenting as Ischemic Pancreatitis in Systemic Lupus Erythematosus

    Directory of Open Access Journals (Sweden)

    Ajit Vyas

    2009-09-01

    Full Text Available Context Antiphospholipid syndrome is often associated with systemic lupus erythematosus. Both syndromes have different clinical manifestations based on organ involvement. Antiphospholipid syndrome commonly causes spontaneous abortions, cerebral vascular occlusion, and deep venous thrombosis. Catastrophic antiphospholipid syndrome occurs when three or more organ systems are affected by thromboses in less than a week. Case report We report a unique case of a young woman with a history of systemic lupus erythematosus and antiphospholipid syndrome who presented with recurrent ischemic pancreatitis. Pancreatitis was refractory to anticoagulation and low dose steroids. Secondary to recurrence of pancreatitis and other organ involvement, she was treated as a presumed case of catastrophic antiphospholipid syndrome. Aggressive treatment with plasmapheresis, corticosteroids, cyclophosphamide, and anticoagulation eventually led to her recovery. Conclusion Awareness of this rare, rapidly fatal medical condition prompts vital, early intervention to improve patients’ survival. This case report aims to add to the limited therapeutic data available as well as suggest a possible approach to treating this rare syndrome with very high morbidity and mortality.

  2. Impact disruption and recovery of the deep subsurface biosphere

    DEFF Research Database (Denmark)

    Cockell, Charles S.; Voytek, Mary A.; Gronstal, Aaaron L

    2012-01-01

    Although a large fraction of the world's biomass resides in the subsurface, there has been no study of the effects of catastrophic disturbance on the deep biosphere and the rate of its subsequent recovery. We carried out an investigation of the microbiology of a 1.76 km drill core obtained from t...

  3. Web 2.0 for Disaster Response and Recovery

    Science.gov (United States)

    Schmidt, Gregory

    2010-01-01

    Successful disaster response is an exercise in managing human resources under very difficult conditions. Catastrophic disasters can disrupt both the physical communication networks and the social networks critical to efficient response and recovery. While a well-designed disaster plan serves as a framework, it often requires communication and…

  4. Dynamical systems V bifurcation theory and catastrophe theory

    CERN Document Server

    1994-01-01

    Bifurcation theory and catastrophe theory are two of the best known areas within the field of dynamical systems. Both are studies of smooth systems, focusing on properties that seem to be manifestly non-smooth. Bifurcation theory is concerned with the sudden changes that occur in a system when one or more parameters are varied. Examples of such are familiar to students of differential equations, from phase portraits. Moreover, understanding the bifurcations of the differential equations that describe real physical systems provides important information about the behavior of the systems. Catastrophe theory became quite famous during the 1970's, mostly because of the sensation caused by the usually less than rigorous applications of its principal ideas to "hot topics", such as the characterization of personalities and the difference between a "genius" and a "maniac". Catastrophe theory is accurately described as singularity theory and its (genuine) applications. The authors of this book, the first printing of w...

  5. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements.

    Science.gov (United States)

    Liu, Pengfei; Erez, Ayelet; Nagamani, Sandesh C Sreenath; Dhar, Shweta U; Kołodziejska, Katarzyna E; Dharmadhikari, Avinash V; Cooper, M Lance; Wiszniewska, Joanna; Zhang, Feng; Withers, Marjorie A; Bacino, Carlos A; Campos-Acevedo, Luis Daniel; Delgado, Mauricio R; Freedenberg, Debra; Garnica, Adolfo; Grebe, Theresa A; Hernández-Almaguer, Dolores; Immken, LaDonna; Lalani, Seema R; McLean, Scott D; Northrup, Hope; Scaglia, Fernando; Strathearn, Lane; Trapane, Pamela; Kang, Sung-Hae L; Patel, Ankita; Cheung, Sau Wai; Hastings, P J; Stankiewicz, Paweł; Lupski, James R; Bi, Weimin

    2011-09-16

    Complex genomic rearrangements (CGRs) consisting of two or more breakpoint junctions have been observed in genomic disorders. Recently, a chromosome catastrophe phenomenon termed chromothripsis, in which numerous genomic rearrangements are apparently acquired in one single catastrophic event, was described in multiple cancers. Here, we show that constitutionally acquired CGRs share similarities with cancer chromothripsis. In the 17 CGR cases investigated, we observed localization and multiple copy number changes including deletions, duplications, and/or triplications, as well as extensive translocations and inversions. Genomic rearrangements involved varied in size and complexities; in one case, array comparative genomic hybridization revealed 18 copy number changes. Breakpoint sequencing identified characteristic features, including small templated insertions at breakpoints and microhomology at breakpoint junctions, which have been attributed to replicative processes. The resemblance between CGR and chromothripsis suggests similar mechanistic underpinnings. Such chromosome catastrophic events appear to reflect basic DNA metabolism operative throughout an organism's life cycle.

  6. Catastrophic ice lake collapse in Aram Chaos, Mars

    CERN Document Server

    Roda, Manuel; Zegers, Tanja E; Oosthoek, Jelmer H P

    2014-01-01

    Hesperian chaotic terrains have been recognized as the source of outflow channels formed by catastrophic outflows. Four main scenarios have been proposed for the formation of chaotic terrains that involve different amounts of water and single or multiple outflow events. Here, we test these scenarios with morphological and structural analyses of imagery and elevation data for Aram Chaos in conjunction with numerical modeling of the morphological evolution of the catastrophic carving of the outflow valley. The morphological and geological analyses of Aram Chaos suggest large-scale collapse and subsidence (1500 m) of the entire area, which is consistent with a massive expulsion of liquid water from the subsurface in one single event. The combined observations suggest a complex process starting with the outflow of water from two small channels, followed by continuous groundwater sapping and headward erosion and ending with a catastrophic lake rim collapse and carving of the Aram Valley, which is synchronous with ...

  7. Stagewise cognitive development: an application of catastrophe theory.

    Science.gov (United States)

    van der Maas, H L; Molenaar, P C

    1992-07-01

    In this article an overview is given of traditional methodological approaches to stagewise cognitive developmental research. These approaches are evaluated and integrated on the basis of catastrophe theory. In particular, catastrophe theory specifies a set of common criteria for testing the discontinuity hypothesis proposed by Piaget. Separate criteria correspond to distinct methods used in cognitive developmental research. Such criteria are, for instance, the detection of spurts in development, bimodality of test scores, and increased variability of responses during transitional periods. When a genuine stage transition is present, these criteria are expected to be satisfied. A revised catastrophe model accommodating these criteria is proposed for the stage transition in cognitive development from the preoperational to the concrete operational stage.

  8. Strategic reasoning and bargaining in catastrophic climate change games

    Science.gov (United States)

    Verendel, Vilhelm; Johansson, Daniel J. A.; Lindgren, Kristian

    2016-03-01

    Two decades of international negotiations show that agreeing on emission levels for climate change mitigation is a hard challenge. However, if early warning signals were to show an upcoming tipping point with catastrophic damage, theory and experiments suggest this could simplify collective action to reduce greenhouse gas emissions. At the actual threshold, no country would have a free-ride incentive to increase emissions over the tipping point, but it remains for countries to negotiate their emission levels to reach these agreements. We model agents bargaining for emission levels using strategic reasoning to predict emission bids by others and ask how this affects the possibility of reaching agreements that avoid catastrophic damage. It is known that policy elites often use a higher degree of strategic reasoning, and in our model this increases the risk for climate catastrophe. Moreover, some forms of higher strategic reasoning make agreements to reduce greenhouse gases unstable. We use empirically informed levels of strategic reasoning when simulating the model.

  9. A critical look at risk assessments for global catastrophes.

    Science.gov (United States)

    Kent, Adrian

    2004-02-01

    Recent articles by Busza et al. (BJSW) and Dar et al. (DDH) argue that astrophysical data can be used to establish small bounds on the risk of a "killer strangelet" catastrophe scenario in the RHIC and ALICE collider experiments. The case for the safety of the experiments set out by BJSW does not rely solely on these bounds, but on theoretical arguments, which BJSW find sufficiently compelling to firmly exclude any possibility of catastrophe. Nonetheless, DDH and other commentators (initially including BJSW) suggested that these empirical bounds alone do give sufficient reassurance. This seems unsupportable when the bounds are expressed in terms of expectation value-a good measure, according to standard risk analysis arguments. For example, DDH's main bound, p(catastrophe) future generations, a catastrophe risk no higher than approximately 10(-15) per year would be required for consistency with established policy for radiation hazard risk minimization. Allowing for risk aversion and for future lives, a respectable case can be made for requiring a bound many orders of magnitude smaller. In summary, the costs of small risks of catastrophe have been significantly underestimated by BJSW (initially), by DDH, and by other commentators. Future policy on catastrophe risks would be more rational, and more deserving of public trust, if acceptable risk bounds were generally agreed upon ahead of time and if serious research on whether those bounds could indeed be guaranteed was carried out well in advance of any hypothetically risky experiment, with the relevant debates involving experts with no stake in the experiments under consideration.

  10. Application of Catastrophe Theory in 3D Seismic Data Interpretation of Coal Mine

    Institute of Scientific and Technical Information of China (English)

    ZHAO Mu-hua; YANG Wen-qiang; CUI Hui-xia

    2005-01-01

    In order to detect fault exactly and quickly, cusp catastrophe theory is used to interpret 3D coal seismic data in this paper. By establishing a cusp model, seismic signal is transformed into standard form of cusp catastrophe and catastrophe parameters, including time-domain catastrophe potential, time-domain catastrophe time, frequency-domain catastrophe potential and frequency- domain degree, are calculated. Catastrophe theory is used in 3D seismic structural interpretation in coal mine. The results show that the position of abnormality of the catastrophe parameter profile or curve is related to the location of fault, and the cusp catastrophe theory is effective to automatically pick up geology information and improve the interpretation precision in 3D seismic data.

  11. Heritability of pain catastrophizing and associations with experimental pain outcomes: a twin study.

    Science.gov (United States)

    Trost, Zina; Strachan, Eric; Sullivan, Michael; Vervoort, Tine; Avery, Ally R; Afari, Niloofar

    2015-03-01

    This study used a twin paradigm to examine genetic and environmental contributions to pain catastrophizing and the observed association between pain catastrophizing and cold-pressor task (CPT) outcomes. Male and female monozygotic (n = 206) and dizygotic twins (n = 194) from the University of Washington Twin Registry completed a measure of pain catastrophizing and performed a CPT challenge. As expected, pain catastrophizing emerged as a significant predictor of several CPT outcomes, including cold-pressor Immersion Tolerance, Pain Tolerance, and Delayed Pain Rating. The heritability estimate for pain catastrophizing was found to be 37% with the remaining 63% of variance attributable to unique environmental influence. Additionally, the observed associations between pain catastrophizing and CPT outcomes were not found attributable to shared genetics or environmental exposure, which suggests a direct relationship between catastrophizing and experimental pain outcomes. This study is the first to examine the heritability of pain catastrophizing and potential processes by which pain catastrophizing is related to experimental pain response.

  12. Catastrophic antiphospholipid syndrome presenting as fever of unknown origin

    Directory of Open Access Journals (Sweden)

    Fatma I Al-Beladi

    2012-01-01

    Full Text Available Antiphospholipid syndrome is characterized by the presence of antiphospholipid antibodies with characteristic clinical manifestation, which include venous, arterial thrombosis, thrombotic microangiopathy, and recurrent fetal loss. The syndrome can be secondary to many causes including systemic lupus erythematosus (SLE or "primary" antiphospholipid syndrome (APLS. We report a case of a man with catastrophic antiphospholipid syndrome (CAPS, which occurs when three or more organ systems are affected by thrombosis in less than a week. Catastrophic antiphospholipid syndrome is uncommon but often fatal. The patient received a successful treatment that controlled this disease and included intravenous heparin, antiplatelet, intravenous corticosteroid, and plasmapheresis.

  13. Catastrophic antiphospholipid syndrome presenting as fever of unknown origin.

    Science.gov (United States)

    Al-Beladi, Fatma I

    2012-01-01

    Antiphospholipid syndrome is characterized by the presence of antiphospholipid antibodies with characteristic clinical manifestation, which include venous, arterial thrombosis, thrombotic microangiopathy, and recurrent fetal loss. The syndrome can be secondary to many causes including systemic lupus erythematosus (SLE) or "primary" antiphospholipid syndrome (APLS). We report a case of a man with catastrophic antiphospholipid syndrome (CAPS), which occurs when three or more organ systems are affected by thrombosis in less than a week. Catastrophic antiphospholipid syndrome is uncommon but often fatal. The patient received a successful treatment that controlled this disease and included intravenous heparin, antiplatelet, intravenous corticosteroid, and plasmapheresis.

  14. Predicting catastrophes in nonlinear dynamical systems by compressive sensing.

    Science.gov (United States)

    Wang, Wen-Xu; Yang, Rui; Lai, Ying-Cheng; Kovanis, Vassilios; Grebogi, Celso

    2011-04-15

    An extremely challenging problem of significant interest is to predict catastrophes in advance of their occurrences. We present a general approach to predicting catastrophes in nonlinear dynamical systems under the assumption that the system equations are completely unknown and only time series reflecting the evolution of the dynamical variables of the system are available. Our idea is to expand the vector field or map of the underlying system into a suitable function series and then to use the compressive-sensing technique to accurately estimate the various terms in the expansion. Examples using paradigmatic chaotic systems are provided to demonstrate our idea.

  15. Predicting catastrophes in nonlinear dynamical systems by compressive sensing

    CERN Document Server

    Wang, Wen-Xu; Lai, Ying-Cheng; Kovanis, Vassilios; Grebogi, Celso

    2011-01-01

    An extremely challenging problem of significant interest is to predict catastrophes in advance of their occurrences. We present a general approach to predicting catastrophes in nonlinear dynamical systems under the assumption that the system equations are completely unknown and only time series reflecting the evolution of the dynamical variables of the system are available. Our idea is to expand the vector field or map of the underlying system into a suitable function series and then to use the compressive-sensing technique to accurately estimate the various terms in the expansion. Examples using paradigmatic chaotic systems are provided to demonstrate our idea.

  16. Pain catastrophizing predicts verbal expression among children with chronic pain and their mothers

    Directory of Open Access Journals (Sweden)

    Shelby L Langer

    2016-03-01

    Full Text Available This study examined intra- and inter-personal associations between pain catastrophizing and verbal expression in 70 children with recurrent abdominal pain and their mothers. Participants independently completed the Pain Catastrophizing Scale. Mothers and children then talked about the child’s pain. Speech was categorized using a linguistic analysis program. Catastrophizing was positively associated with the use of negative emotion words by both mothers and children. In addition, mothers’ catastrophizing was positively associated with both mothers’ and children’s anger word usage, whereas children’s catastrophizing was inversely associated with mothers’ anger word usage. Findings extend the literature on behavioral and interpersonal aspects of catastrophizing.

  17. Anomalous left coronary artery from the pulmonary artery with a large patent ductus arteriosus: aversion of a catastrophe.

    Science.gov (United States)

    Aggarwal, Sanjeev; Delius, Ralph E; Pettersen, Michael D

    2013-01-01

    We present an infant who had an anomalous left coronary artery arising from the pulmonary artery (ALCAPA) and a large patent ductus arteriosus (PDA), who was diagnosed before a potentially catastrophic closure of PDA. In the presence of normal left ventricular function and the absence of coronary artery collaterals, it is difficult to diagnose ALCAPA. A disproportionate degree of left ventricular dilation and severity of mitral valve regurgitation relative to the degree of PDA shunt, and echogenic papillary muscles on an echocardiogram should raise a suspicion of coronary artery anomalies. The infant underwent surgical ligation of PDA with translocation of coronary arteries and had an uneventful recovery.

  18. The Chernobyl Catastrophe. Consequences on Human Health

    Energy Technology Data Exchange (ETDEWEB)

    Yablokov, A.; Labunska, I.; Blokov, I. (eds.)

    2006-04-15

    of estimates of excess mortality resulting from the Chernobyl accident spans an extremely wide range depending upon precisely what is taken into account. The most recent epidemiological evidence, published under the auspices of the Russian Academy of Sciences, suggests that the scale of the problems could be very much greater than predicted by studies published to date. For example, the 2005 IAEA report predicted that 4000 additional deaths would result from the Chernobyl accident. The most recently published figures indicate that in Belarus, Russia and the Ukraine alone the accident resulted in an estimated 200,000 additional deaths between 1990 and 2004. Overall, the available data reveal a considerable range in estimated excess mortalities resulting from the Chernobyl accident, serving to underline the huge uncertainties attached to knowledge of the full impacts of the Chernobyl accident. This report includes some data, which have not been published before in the international arena. In combination with the extensive body of literature which has been published to date, these data indicate that 'official' figures (e.g. the IAEA 2005 evaluation) for morbidity (incidence of disease) and death arising as a direct result of the radioactive contamination released from Chernobyl may grossly underestimate both the local and international impact of the incident. Four population groups appear to have experienced the most severe health effects: (1) accident clean-up workers, or 'liquidators', including civilian and the military personnel drafted to carry out clean-up activities and construct the protective cover for the reactor; (2) evacuees from dangerously contaminated territories inside the 30-km zone around the power plant; (3) residents of the less (but still dangerously) contaminated territories; and (4) children born into the families from all of the above three groups.

  19. Concrete ensemble Kalman filters with rigorous catastrophic filter divergence.

    Science.gov (United States)

    Kelly, David; Majda, Andrew J; Tong, Xin T

    2015-08-25

    The ensemble Kalman filter and ensemble square root filters are data assimilation methods used to combine high-dimensional, nonlinear dynamical models with observed data. Ensemble methods are indispensable tools in science and engineering and have enjoyed great success in geophysical sciences, because they allow for computationally cheap low-ensemble-state approximation for extremely high-dimensional turbulent forecast models. From a theoretical perspective, the dynamical properties of these methods are poorly understood. One of the central mysteries is the numerical phenomenon known as catastrophic filter divergence, whereby ensemble-state estimates explode to machine infinity, despite the true state remaining in a bounded region. In this article we provide a breakthrough insight into the phenomenon, by introducing a simple and natural forecast model that transparently exhibits catastrophic filter divergence under all ensemble methods and a large set of initializations. For this model, catastrophic filter divergence is not an artifact of numerical instability, but rather a true dynamical property of the filter. The divergence is not only validated numerically but also proven rigorously. The model cleanly illustrates mechanisms that give rise to catastrophic divergence and confirms intuitive accounts of the phenomena given in past literature.

  20. A case of seronegative catastrophic antiphospholipid antibody syndrome.

    Science.gov (United States)

    Shreders, Amanda; Bar, Michael

    2013-02-01

    Catastrophic antiphospholipid antibody syndrome (CAPS) is a rare syndrome associated with multiorgan failure that carries a high mortality rate. It has been defined previously by the presence of autoantibodies in a patient with acute multiorgan failure as a result of small vessel occlusion by multiple thrombi. We report a patient who meets all criteria of CAPS except for persistent seronegativity.

  1. The Application of Catastrophe Theory to Medical Image Analysis

    NARCIS (Netherlands)

    Kuijper, Arjan; Florack, L.M.J.

    2002-01-01

    In order to investigate the deep structure of Gaussian scale space images, one needs to understand the behaviour of critical points under the influence of blurring. We show how the mathematical framework of catastrophe theory can be used to describe the various different types of annihilations and c

  2. Enabling Unity of Effort in Response Activities during Complex Catastrophes

    Science.gov (United States)

    2013-03-01

    catastrophe (including any hurricane, tornado, storm, high water , winddriven water , tidal wave, tsunami, earthquake, volcanic eruption , landslide...the Insurrection Act, and the Stafford Act. Perhaps the most efficient means to achieve unity of effort would be to consolidate all forces under a...possible under our federalist system of government, where respective authorities are divided between federal, state and local jurisdictions. The most

  3. Alignment of Lyapunov Vectors: A Quantitative Criterion to Predict Catastrophes?

    Science.gov (United States)

    Beims, Marcus W.; Gallas, Jason A. C.

    2016-11-01

    We argue that the alignment of Lyapunov vectors provides a quantitative criterion to predict catastrophes, i.e. the imminence of large-amplitude events in chaotic time-series of observables generated by sets of ordinary differential equations. Explicit predictions are reported for a Rössler oscillator and for a semiconductor laser with optoelectronic feedback.

  4. Catastrophe Theory: A Unified Model for Educational Change.

    Science.gov (United States)

    Cryer, Patricia; Elton, Lewis

    1990-01-01

    Catastrophe Theory and Herzberg's theory of motivation at work was used to create a model of change that unifies and extends Lewin's two separate stage and force field models. This new model is used to analyze the behavior of academics as they adapt to the changing university environment. (Author/MLW)

  5. Vaginismus : Heightened Harm Avoidance and Pain Catastrophizing Cognitions

    NARCIS (Netherlands)

    Borg, Charmaine; Peters, Madelon L.; Schultz, Willibrord Weijmar; de Jong, Peter J.

    2012-01-01

    Introduction. Catastrophic appraisal of experienced pain may promote hypervigilance and intense pain, while the personality trait of harm avoidance (HA) might prevent the occurrence of correcting such experiences. Women inflicted with vaginismus may enter a self-perpetuating downward spiral of incre

  6. Catastrophic fire deaths: the numbers are back up.

    Science.gov (United States)

    Tremblay, K J

    1994-01-01

    The number of catastrophic multiple-death fires in the United States rose in 1993 from the record low of 1992 to a level more consistent with that of recent years. Despite our efforts to highlight risk factors, we continue to see the same problems year after year.

  7. 7 CFR 402.4 - Catastrophic Risk Protection Endorsement Provisions.

    Science.gov (United States)

    2010-01-01

    ... total household income at or below the national poverty level for a family of four, or less than 50..., provided that you execute a High Risk Land Exclusion Option and obtain a catastrophic risk protection... the landowners must agree in writing to such arrangement and have their social security number...

  8. A catastrophe theory model of the conflict helix, with tests.

    Science.gov (United States)

    Rummel, R J

    1987-10-01

    Macro social field theory has undergone extensive development and testing since the 1960s. One of these has been the articulation of an appropriate conceptual micro model--called the conflict helix--for understanding the process from conflict to cooperation and vice versa. Conflict and cooperation are viewed as distinct equilibria of forces in a social field; the movement between these equilibria is a jump, energized by a gap between social expectations and power, and triggered by some minor event. Quite independently, there also has been much recent application of catastrophe theory to social behavior, but usually without a clear substantive theory and lacking empirical testing. This paper uses catastrophe theory--namely, the butterfly model--mathematically to structure the conflict helix. The social field framework and helix provide the substantive interpretation for the catastrophe theory; and catastrophe theory provides a suitable mathematical model for the conflict helix. The model is tested on the annual conflict and cooperation between India and Pakistan, 1948 to 1973. The results are generally positive and encouraging.

  9. The Application of Catastrophe Theory to Image Analysis

    NARCIS (Netherlands)

    Kuijper, Arjan; Florack, L.M.J.

    2002-01-01

    In order to investigate the deep structure of Gaussian scale space images, one needs to understand the behaviour of critical points under the in flence of blurring. We show how the mathematical framework of catastrophe theory can be used to describe the various different types of annihilations and t

  10. [Establishing the personal identity of the victims in aviation catastrophes].

    Science.gov (United States)

    Abramov, S S; Alekseev, I V; Gedygushev, I A; Zaĭtsev, A B; Isaev, Iu S; Nedel'ko, N F; Miller, V V; Proskurin, V N; Khaĭrulin, E G; Shilin, A V

    1999-01-01

    Algorithm of organization measures and expert investigations is proposed, based on experience gained in expert studies during liquidation of aircraft catastrophes. It permits effective classification, differentiation, and identification of victims and is based on traditional and high technological methods of investigation.

  11. Concrete ensemble Kalman filters with rigorous catastrophic filter divergence

    Science.gov (United States)

    Kelly, David; Majda, Andrew J.; Tong, Xin T.

    2015-01-01

    The ensemble Kalman filter and ensemble square root filters are data assimilation methods used to combine high-dimensional, nonlinear dynamical models with observed data. Ensemble methods are indispensable tools in science and engineering and have enjoyed great success in geophysical sciences, because they allow for computationally cheap low-ensemble-state approximation for extremely high-dimensional turbulent forecast models. From a theoretical perspective, the dynamical properties of these methods are poorly understood. One of the central mysteries is the numerical phenomenon known as catastrophic filter divergence, whereby ensemble-state estimates explode to machine infinity, despite the true state remaining in a bounded region. In this article we provide a breakthrough insight into the phenomenon, by introducing a simple and natural forecast model that transparently exhibits catastrophic filter divergence under all ensemble methods and a large set of initializations. For this model, catastrophic filter divergence is not an artifact of numerical instability, but rather a true dynamical property of the filter. The divergence is not only validated numerically but also proven rigorously. The model cleanly illustrates mechanisms that give rise to catastrophic divergence and confirms intuitive accounts of the phenomena given in past literature. PMID:26261335

  12. Recovery Online

    Science.gov (United States)

    Clark, John R.

    2007-01-01

    Since the founding of Alcoholics Anonymous (AA) in 1935, programs offering opportunity for recovery from alcoholism and other addictions have undergone vast changes. The Internet has created nearly limitless opportunities for recovering people and those seeking recovery to find both meetings and places where they can gather virtually and discuss…

  13. Backup & Recovery

    CERN Document Server

    Preston, W

    2009-01-01

    Packed with practical, freely available backup and recovery solutions for Unix, Linux, Windows, and Mac OS X systems -- as well as various databases -- this new guide is a complete overhaul of Unix Backup & Recovery by the same author, now revised and expanded with over 75% new material.

  14. Catastrophic senescence and semelparity in the Penna aging model

    CERN Document Server

    Pinol, C M N

    2010-01-01

    The catastrophic senescence of the Pacific salmon is among the initial tests used to validate the Penna aging model. Based on the mutation accumulation theory, the sudden decrease in fitness following reproduction may be solely attributed to the semelparity of the species. In this work, we report other consequences of mutation accumulation. Contrary to earlier findings, such dramatic manifestation of aging depends not only on the choice of breeding strategy but also on the value of the reproduction age, R, and the mutation threshold, T. Senescence is catastrophic when T\\leq R. As the organism's tolerance for harmful genetic mutations increases, the aging process becomes more gradual. We observe senescence that is threshold dependent whenever T>R. That is, the sudden drop in survival rate occurs at age equal to the mutation threshold value.

  15. Le gouvernement mondial des catastrophes « naturelles »

    Directory of Open Access Journals (Sweden)

    Sandrine Revet

    2015-01-01

    Full Text Available Depuis la fin des années 1980, une tentative de gouvernement international des catastrophes dites « naturelles » a progressivement vu le jour. Celui-ci prétend coordonner à l’échelle internationale des actions relevant à la fois de la prévention des risques et de la gestion de crise. L’article propose de décrire ce processus en en retraçant les grandes étapes, depuis la Décennie internationale pour la prévention des catastrophes naturelles de l’ONU (1990-1999 jusqu’aux négociations ayant mené au Cadre d’action de Hyogo (CAH, 2005-2015. Il mettra en lumière les grandes tensions qui ont animé ce processus et qui révèlent les différentes approches adoptées face aux catastrophes naturelles : mettre en place des politiques de prévention qui misent sur la transformation en profondeur des choix de développement ou insister sur les capacités technologiques de prévision, de communication de l’alerte et de gestion des crises provoquées par les catastrophes lorsqu’elles surviennent ? Nous nous intéresserons enfin aux enjeux qui seront soulevés en 2015 par les négociations du prochain cadre d’action international CAH2 lors de la conférence mondiale qui se tiendra à Sendaï au Japon.

  16. Bifurcation and catastrophe of seepage flow system in broken rock

    Institute of Scientific and Technical Information of China (English)

    MIAO Xie-xing; LI Shun-cai; CHEN Zhan-qing

    2009-01-01

    The study of dynamical behavior of water or gas flows in broken rock is a basic research topic among a series of key projects about stability control of the surrounding rocks in mines and the prevention of some disasters such as water inrush or gas outburst and the protection of the groundwater resource. It is of great theoretical and engineering importance in respect of promo-tion of security in mine production and sustainable development of the coal industry. According to the non-Darcy property of seepage flow in broken rock dynamic equations of non-Darcy and non-steady flows in broken rock are established. By dimensionless transformation, the solution diagram of steady-states satisfying the given boundary conditions is obtained. By numerical analysis of low relaxation iteration, the dynamic responses corresponding to the different flow parameters have been obtained. The stability analysis of the steady-states indicate that a saddle-node bifurcaton exists in the seepage flow system of broken rock. Consequently, using catastrophe theory, the fold catastrophe model of seepage flow instability has been obtained. As a result, the bifurcation curves of the seepage flow systems with different control parameters are presented and the standard potential function is also given with respect to the generalized state variable for the fold catastrophe of a dynamic system of seepage flow in broken rock.

  17. Catastrophic subsidence: An environmental hazard, shelby county, Alabama

    Science.gov (United States)

    Lamoreaux, Philip E.; Newton, J. G.

    1986-03-01

    Induced sinkholes (catastrophic subsidence) are those caused or accelerated by human activities These sinkholes commonly result from a water level decline due to pumpage Construction activities in a cone of depression greatly increases the likelihood of sinkhole occurrence Almost all occur where cavities develop in unconsolidated deposits overlying solution openings in carbonate rocks. Triggering mechanisms resulting from water level declines are (1) loss of buoyant support of the water, (2) increased gradient and water velocity, (3) water-level fluctuations, and (4) induced recharge Construction activities triggering sinkhole development include ditching, removing overburden, drilling, movement of heavy equipment, blasting and the diversion and impoundment of drainage Triggering mechanisms include piping, saturation, and loading Induced sinkholes resulting from human water development/management activities are most predictable in a youthful karst area impacted by groundwater withdrawals Shape, depth, and timing of catastrophic subsidence can be predicted in general terms Remote sensing techniques are used in prediction of locations of catastrophic subsidence. This provides a basis for design and relocation of structures such as a gas pipeline, dam, or building Utilization of techniques and a case history of the relocation of a pipeline are described

  18. Evidence for Middle Amazonian catastrophic flooding and glaciation on Mars

    Science.gov (United States)

    Rodríguez, J. Alexis P.; Gulick, Virginia C.; Baker, Victor R.; Platz, Thomas; Fairén, Alberto G.; Miyamoto, Hideaki; Kargel, Jeffrey S.; Rice, James W.; Glines, Natalie

    2014-11-01

    Early geologic investigations of Mars revealed some of the largest channels in the Solar System (outflow channels), which appear to have mostly developed ∼3 byr ago. These channels have been the subject of much scientific inquiry since the 1970s and proposed formative processes included surface erosion by catastrophic floods, glaciers, debris flows and lava flows. Based on the analysis of newly acquired Mars Reconnaissance Orbiter (MRO) Context (CTX, 5.15-5.91 m/pixel) and High Resolution Imaging Science Experiment (HiRISE, 25-50 cm/pixel) image data, we have identified a few locations contained within relatively narrow canyons of the southern circum-Chryse outflow channels that retain well-preserved decameter/hectometer-scale landform assemblages. These terrains include landforms consistent in shape, dimension and overall assemblage to those produced by catastrophic floods, and at one location, to glacial morphologies. Impact crater statistics for four of these surfaces, located within upstream, midstream and downstream outflow channel surfaces, yield an age estimate of ∼600 myr. This suggests that the southern circum-Chryse outflow channels were locally resurfaced by some of the most recent catastrophic floods on the planet, and that these floods coexisted within regional glacier environments as recently as during the Middle Amazonian.

  19. Recovery post ICU.

    Science.gov (United States)

    Jones, Christina

    2014-10-01

    Many ICU patients struggle to recovery following critical illness and may be left with physical, cognitive and psychological problems, which have a negative impact on their quality of life. Gross muscle mass loss and weakness can take some months to recover after the patients' Intensive Care Unit (ICU) discharge, in addition critical illness polyneuropathies can further complicate physical recovery. Psychological problems such as anxiety, depression and post traumatic stress disorder (PTSD) are common and have an negative impact on the patients' ability to engage in rehabilitation after ICU discharge. Finally cognitive deficit affecting memory can be a significant problem. The first step in helping patients to recover from such a devastating illness is to recognise those who have the greatest need and target interventions. Research now suggests that there are interventions that can accelerate physical recovery and reduce the incidence of psychological problems such as anxiety, depression and PTSD. Cognitive rehabilitation, however, is still in its infancy. This review will look at the research into patients' recovery and what can be done to improve this where needed.

  20. Psychological Trauma in the Workplace: Variation of Incident Severity among Industry Settings and between Recurring vs Isolated Incidents

    Directory of Open Access Journals (Sweden)

    GS DeFraia

    2015-07-01

    Full Text Available Background: Psychologically traumatic workplace events (known as critical incidents occur within various work environments, with workgroups in certain industries vulnerable to multiple incidents. With the increasing prevalence of incidents in the USA, incident response is a growing practice area within occupational medicine, industrial psychology, occupational social work and other occupational health professions.Objective: To analyze a measure of incident severity based on level of disruption to the workplace and explore whether incident severity varied among different industry settings or between workgroups experiencing multiple vs single traumatic incidents.Methods: Administrative data mining was employed to examine practice data from a workplace trauma response unit in the USA. Bivariate analyses were conducted to test whether scores from an instrument measuring incident severity level varied among industry settings or between workgroups impacted by multiple vs isolated events.Results: Incident severity level differed among various industry settings. Banks, retail stores and fast food restaurants accounted for the most severe incidents, while industrial and manufacturing sites reported less severe incidents. Workgroups experiencing multiple incidents reported more severe incidents than workgroups experiencing a single incident.Conclusion: Occupational health practitioners should be alert to industry differences in several areas: pre-incident resiliency training, the content of business recovery plans, assessing worker characteristics, strategies to assist continuous operations and assisting workgroups impacted by multiple or severe incidents.

  1. Critical incident reporting systems.

    Science.gov (United States)

    Ahluwalia, Jag; Marriott, Lin

    2005-02-01

    Approximately 10% of all hospital admissions are complicated by critical incidents in which harm is caused to the patient - this amounts to more than 850,000 incidents annually. Critical incident reporting (CIR) systems refer to the structured reporting, collation and analysis of such incidents. This article describes the attributes required for an effective CIR system. Example neonatal trigger events and a management pathway for handling a critical incident report are described. The benefits and limitations of CIR systems, reactive and prospective approaches to the analysis of actual or potential critical incidents and the assessment of risk are also reviewed. Individual human error is but one contributor in the majority of critical incidents. Recognition of this and the fostering of an organisational culture that views critical incident reports as an opportunity to learn and to improve future patient care is vital if CIR systems are to be effective.

  2. Disaster Debris Recovery Database - Recovery

    Data.gov (United States)

    U.S. Environmental Protection Agency — The US EPA Region 5 Disaster Debris Recovery Database includes public datasets of over 6,000 composting facilities, demolition contractors, transfer stations,...

  3. Incident Information Management Tool

    CERN Document Server

    Pejovic, Vladimir

    2015-01-01

    Flaws of\tcurrent incident information management at CMS and CERN\tare discussed. A new data\tmodel for future incident database is\tproposed and briefly described. Recently developed draft version of GIS-­‐based tool for incident tracking is presented.

  4. Situational vs. dispositional measurement of catastrophizing: Associations with pain responses in multiple samples

    Science.gov (United States)

    Campbell, Claudia M.; Kronfli, Tarek; Buenaver, Luis F.; Smith, Michael T.; Berna, Chantal; Haythornthwaite, Jennifer A.; Edwards, Robert R.

    2009-01-01

    Catastrophizing is widely recognized as an important risk factor for adverse pain-related outcomes. However, questions remain surrounding the details of its assessment. In particular, recent laboratory studies suggest that evaluation of “situational” catastrophizing (i.e., catastrophizing measured during or directly after the administration of noxious stimulation) may provide information distinct from that obtained by standard, or “dispositional” measures which assess individuals’ recall of catastrophizing in daily life. However, comparatively little research has systematically investigated the inter-relationships and properties of these two different forms of pain-related catastrophizing. The current study evaluated both situational and dispositional catastrophizing measures within multiple samples: healthy individuals (N=84), patients with painful temporomandibular joint disorders (TMD; N=48), and patients with painful arthritis (N=43). All participants first completed the Pain Catastrophizing Scale (PCS)49, and then underwent psychophysical pain testing, which included heat, cold, and pressure pain. Participants then completed a situational catastrophizing measure with reference to the laboratory pain he/she had just undergone. Situational catastrophizing scores were not significantly correlated with dispositional PCS scores in the healthy participants and arthritis patients, though they were associated in TMD patients. Situational catastrophizing was more strongly associated with experimental pain responses than dispositional PCS scores for the healthy subjects and arthritis patients. In general, higher levels of situational catastrophizing were associated with lower pain thresholds and higher pain ratings across all 3 samples. The findings highlight the importance of multi-dimensional assessment of pain-related catastrophizing, and suggests a role for measuring catastrophizing related to specific, definable events. PMID:20439057

  5. Recovery Spirituality

    Directory of Open Access Journals (Sweden)

    Ernest Kurtz

    2015-01-01

    Full Text Available There is growing interest in Alcoholics Anonymous (A.A. and other secular, spiritual, and religious frameworks of long-term addiction recovery. The present paper explores the varieties of spiritual experience within A.A., with particular reference to the growth of a wing of recovery spirituality promoted within A.A. It is suggested that the essence of secular spirituality is reflected in the experience of beyond (horizontal and vertical transcendence and between (connection and mutuality and in six facets of spirituality (Release, Gratitude, Humility, Tolerance, Forgiveness, and a Sense of Being-at-home shared across religious, spiritual, and secular pathways of addiction recovery. The growing varieties of A.A. spirituality (spanning the “Christianizers” and “Seculizers” reflect A.A.’s adaptation to the larger diversification of religious experience and the growing secularization of spirituality across the cultural contexts within which A.A. is nested.

  6. Blue sky catastrophe as applied to modeling of cardiac rhythms

    Science.gov (United States)

    Glyzin, S. D.; Kolesov, A. Yu.; Rozov, N. Kh.

    2015-07-01

    A new mathematical model for the electrical activity of the heart is proposed. The model represents a special singularly perturbed three-dimensional system of ordinary differential equations with one fast and two slow variables. A characteristic feature of the system is that its solution performs nonclassical relaxation oscillations and simultaneously undergoes a blue sky catastrophe bifurcation. Both these factors make it possible to achieve a phenomenological proximity between the time dependence of the fast component in the model and an ECG of the human heart.

  7. ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    DEFF Research Database (Denmark)

    Toledo Lazaro, Luis Ignacio; Altmeyer, Matthias; Rask, Maj-Britt;

    2013-01-01

    induced breakage of stalled forks even in cells with active ATR. Thus, ATR-mediated suppression of dormant origins shields active forks against irreversible breakage via preventing exhaustion of nuclear RPA. This study elucidates how replicating genomes avoid destabilizing DNA damage. Because cancer cells...... origin firing generates an excess of single-stranded DNA that exhausts the nuclear pool of RPA. Partial reduction of RPA accelerated fork breakage, and forced elevation of RPA was sufficient to delay such "replication catastrophe" even in the absence of ATR activity. Conversely, unscheduled origin firing...

  8. Spontaneous Recovery

    Science.gov (United States)

    Rescorla, Robert A.

    2004-01-01

    Spontaneous recovery from extinction is one of the most basic phenomena of Pavlovian conditioning. Although it can be studied by using a variety of designs, some procedures are better than others for identifying the involvement of underlying learning processes. A wide range of different learning mechanisms has been suggested as being engaged by…

  9. Depolymerizing kinesins Kip3 and MCAK shape cellular microtubule architecture by differential control of catastrophe.

    Science.gov (United States)

    Gardner, Melissa K; Zanic, Marija; Gell, Christopher; Bormuth, Volker; Howard, Jonathon

    2011-11-23

    Microtubules are dynamic filaments whose ends alternate between periods of slow growth and rapid shortening as they explore intracellular space and move organelles. A key question is how regulatory proteins modulate catastrophe, the conversion from growth to shortening. To study this process, we reconstituted microtubule dynamics in the absence and presence of the kinesin-8 Kip3 and the kinesin-13 MCAK. Surprisingly, we found that, even in the absence of the kinesins, the microtubule catastrophe frequency depends on the age of the microtubule, indicating that catastrophe is a multistep process. Kip3 slowed microtubule growth in a length-dependent manner and increased the rate of aging. In contrast, MCAK eliminated the aging process. Thus, both kinesins are catastrophe factors; Kip3 mediates fine control of microtubule length by narrowing the distribution of maximum lengths prior to catastrophe, whereas MCAK promotes rapid restructuring of the microtubule cytoskeleton by making catastrophe a first-order random process.

  10. Nuclear catastrophe in Japan. Health consequences resulting from Fukushima; Atomkatastrophe in Japan. Gesundheitliche Folgen von Fukushima

    Energy Technology Data Exchange (ETDEWEB)

    Paulitz, Henrik; Eisenberg, Winfrid; Thiel, Reinhold

    2013-03-06

    On 11 March 2011, a nuclear catastrophe occurred at the Fukushima Dai-ichi nuclear power plant in Japan in the wake of an earthquake and due to serious safety deficiencies. This resulted in a massive and prolonged release of radioactive fission and decay products. Approximately 20% of the radioactive substances released into the atmosphere have led to the contamination of the landmass of Japan with 17,000 becquerels per square meter of cesium-137 and a comparable quantity of cesium-134. The initial health consequences of the nuclear catastrophe are already now, after only two years, scientifically verifiable. Similar to the case of Chernobyl, a decline in the birth rate was documented nine months after the nuclear catastrophe. Throughout Japan, the total drop in number of births in December 2011 was 4362, with the Fukushima Prefecture registering a decline of 209 births. Japan also experienced a rise in infant mortality, with 75 more children dying in their first year of life than expected statistically. In the Fukushima Prefecture alone, some 55,592 children were diagnosed with thyroid gland nodules or cysts. In contrast to cysts and nodules found in adults, these findings in children must be classified as precancerous. There were also the first documented cases in Fukushima of thyroid cancer in children. The present document undertakes three assessments of the expected incidence of cancer resulting from external exposure to radiation. These are based on publications in scientific journals on soil contamination in 47 prefectures in Japan, the average total soil contamination, and, in the third case, on local dose rate measurements in the fall of 2012. Taking into consideration the shielding effect of buildings, the medical organization IPPNW has calculated the collective lifetime doses for individuals at 94,749 manSv, 206,516 manSv, and 118,171 manSv, respectively. In accordance with the risk factors set by the European Committee on Radiation Risk (ECRR) for death

  11. Do we need a communal coping model of pain catastrophizing? An alternative explanation

    OpenAIRE

    2006-01-01

    In this topical review, a case is made for placing pain catastrophizing within the transactional stress and coping model of Lazarus and Folkman (1984). It is argued that the CCM in its current formulation might actually contribute to the conceptual confusion around the construct of pain catastrophizing that was mentioned previously. This finally leads to the question of whether we actually need a CCM of catastrophizing.

  12. Plasma Exchange in the Management of Catastrophic Antiphospholipid Syndrome

    Directory of Open Access Journals (Sweden)

    Dimitri Titeca-Beauport

    2016-01-01

    Full Text Available Objective. Report of a case of catastrophic antiphospholipid syndrome (CAPS with multiple organ involvement leading to a life-threatening condition despite early combination corticosteroid and heparin therapy. Initiation of plasma exchange led to rapid improvement of the patient’s general condition. Design. Case report. Setting. University teaching hospital medical intensive care unit. Patient. Single case: 52-year-old man hospitalized for catastrophic antiphospholipid syndrome (CAPS with cardiac, renal, and cutaneous involvement. Despite early methylprednisolone and heparin therapy, the patient’s condition progressively deteriorated, resulting in acute renal failure, right adrenal hemorrhage, and pulmonary involvement, leading to acute respiratory distress on day 6, requiring high-flow nasal cannula oxygen therapy with FiO2 of 1.0. Interventions. Plasma exchange was started on day 6. Endpoints and Main Results. A marked improvement of the patient’s general condition was observed after initiation of plasma exchange, with successful weaning of oxygen therapy and normalization of platelet count, troponin, and serum creatinine within four days. Conclusions. This case illustrates the efficacy of plasma exchange in CAPS and the difficulty for physicians to determine the optimal timing of plasma exchange.

  13. "Till destruction sicken": the catastrophe of mind in Macbeth.

    Science.gov (United States)

    Tarantelli, Carole Beebe

    2010-12-01

    The author examines the tragedy of Macbeth from the vertex of its portrait of the effects of the hero's abandonment to the "blindest fury of destructiveness" (Freud, 1930, p. 121), using aspects of psychoanalytic thought to illuminate the theme. She affirms that Macbeth's immediate transformation in phantasy from loyal subject to future assassin threatens to flood his psyche with the uncontainable energy of destruction and thus to produce a psychic catastrophe. The remainder of the play is then examined as a representation of Macbeth's attempts to defend himself from that catastrophe: the only objects whose existence he can tolerate are those that cannot challenge his possession of the crown, which leads him to attempt to destroy all opposition. Since this is impossible, his alternative is to denude his mind of its perception of the reality in which the actions of others will inevitably produce future transformations which he is unable to control. The play's last soliloquy anticipates the final state, the repose of emptiness; it portrays a mind, emptied of emotion, looking at a world which it has denuded of meaning.

  14. Plasma Exchange in the Management of Catastrophic Antiphospholipid Syndrome

    Science.gov (United States)

    Salle, Valery; Kontar, Loay; Maizel, Julien

    2016-01-01

    Objective. Report of a case of catastrophic antiphospholipid syndrome (CAPS) with multiple organ involvement leading to a life-threatening condition despite early combination corticosteroid and heparin therapy. Initiation of plasma exchange led to rapid improvement of the patient's general condition. Design. Case report. Setting. University teaching hospital medical intensive care unit. Patient. Single case: 52-year-old man hospitalized for catastrophic antiphospholipid syndrome (CAPS) with cardiac, renal, and cutaneous involvement. Despite early methylprednisolone and heparin therapy, the patient's condition progressively deteriorated, resulting in acute renal failure, right adrenal hemorrhage, and pulmonary involvement, leading to acute respiratory distress on day 6, requiring high-flow nasal cannula oxygen therapy with FiO2 of 1.0. Interventions. Plasma exchange was started on day 6. Endpoints and Main Results. A marked improvement of the patient's general condition was observed after initiation of plasma exchange, with successful weaning of oxygen therapy and normalization of platelet count, troponin, and serum creatinine within four days. Conclusions. This case illustrates the efficacy of plasma exchange in CAPS and the difficulty for physicians to determine the optimal timing of plasma exchange. PMID:27833765

  15. Catastrophic failure in complex socio-technical systems

    Energy Technology Data Exchange (ETDEWEB)

    Weir, D. [Intercultural Management, Rue Dostoievski, BP 085, 06902 Sophia Antipolis (France)]. E-mail: dweir@tinyworld.co.uk

    2004-07-01

    This paper reviews the sequences leading to catastrophic failures in complex socio-technical systems. It traces some of the elements of an analytic framework to that proposed by Beer in Decision and Control, first published in 1966, and argues that these ideas are centrally relevant to a topic on which research interest has developed subsequently, the study of crises, catastrophes and disasters in complex socio-technical systems in high technology sectors. But while the system perspective is central, it is not by itself entirely adequate. The problems discussed cannot be discussed simply in terms of system parameters like variety, redundancy and complexity. Much empirical research supports the view that these systems typically operate in degraded mode. The degradations may be primarily initiated within the social components of the socio-technical system. Such variables as hierarchical position, actors' motivations and intentions are relevant to explain the ways in which communication systems typically operate to filter out messages from lower participants and to ignore the 'soft signals' issuing from small-scale and intermittent malfunctions. (author)

  16. Catastrophe model of the accident process, safety climate, and anxiety.

    Science.gov (United States)

    Guastello, Stephen J; Lynn, Mark

    2014-04-01

    This study aimed (a) to address the evidence for situational specificity in the connection between safety climate to occupational accidents, (b) to resolve similar issues between anxiety and accidents, (c) to expand and develop the concept of safety climate to include a wider range of organizational constructs, (d) to assess a cusp catastrophe model for occupational accidents where safety climate and anxiety are treated as bifurcation variables, and environ-mental hazards are asymmetry variables. Bifurcation, or trigger variables can have a positive or negative effect on outcomes, depending on the levels of asymmetry, or background variables. The participants were 1262 production employees of two steel manufacturing facilities who completed a survey that measured safety management, anxiety, subjective danger, dysregulation, stressors and hazards. Nonlinear regression analyses showed, for this industry, that the accident process was explained by a cusp catastrophe model in which safety management and anxiety were bifurcation variables, and hazards, age and experience were asymmetry variables. The accuracy of the cusp model (R2 = .72) exceeded that of the next best log-linear model (R2 = .08) composed from the same survey variables. The results are thought to generalize to any industry where serious injuries could occur, although situationally specific effects should be anticipated as well.

  17. Relationship of Fault Geometry to Catastrophic Outflow on Mars

    Science.gov (United States)

    Davatzes, A.; Gulick, V.

    2006-12-01

    We present results from studies of large outflow channels on Mars that suggest fault morphology is a critical factor for the trapping and catastrophic release of water on Mars, resulting in large flooding events. On Earth, hot springs are commonly concentrated around fault relays, bends, and fault tips, where jointing forms in zones of concentrated stress promoting tensile failure. Examples of fault controlled hydrothermal activity have been documented in the Coso Geothermal Field in California, Southern Seismic Zone in Iceland, Waiotapu Geothermal Field in New Zealand, Killoran Fault in Ireland, and throughout the southwestern United States. On Earth, abrupt changes in the water table, as well as the formation of sand-boils and springs, are associated with earthquakes, and their spatial distribution is related to the geometry of the earthquake slip patch. A similar process may occur on Mars, where hydrothermal waters collect in highly fractured zones at fault relays, and are released catastrophically during an earthquake event. Two examples of large outflow channels on Mars, Mangala and Athabasca Valles, appear to be sourced in a relay zone. Other Martian examples show sourcing at fault bends and fault tips. Data from the instruments on Mars Reconnaissance Orbiter will help us to further understand this mechanism by which large flood events may occur. High resolution images from HiRISE will be used to map these fault systems and estimate outflow rates, and data from CRISM will be used to identify regions of past high temperature fluid flow on the surface of Mars.

  18. Rituximab use in the catastrophic antiphospholipid syndrome: descriptive analysis of the CAPS registry patients receiving rituximab.

    Science.gov (United States)

    Berman, Horacio; Rodríguez-Pintó, Ignasi; Cervera, Ricard; Morel, Nathalie; Costedoat-Chalumeau, Nathalie; Erkan, Doruk; Shoenfeld, Yehuda; Espinosa, Gerard

    2013-09-01

    The catastrophic variant of the antiphospholipid syndrome (APS) is characterized by thrombosis in multiple organs developing over a short period of time. First-line treatment for the catastrophic APS is the combination of anticoagulation plus corticosteroids plus plasma exchange and/or intravenous immunoglobulin. Despite this regimen, the mortality remains high and new treatment options are needed. By a systematic review of the Catastrophic APS Registry (CAPS Registry), we identified 20 patients treated with rituximab. The purpose of this study is to describe the clinical manifestations, laboratory features, and outcomes of rituximab-treated CAPS patients. In addition, the rationale for using rituximab in catastrophic APS is discussed.

  19. Agricultural Mechanism of Spreading Catastrophe Risk in China and Legislation Conception

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    This paper introduces agricultural catastrophe and its characteristics,and conducts comparative analysis on existing mechanism of spreading agricultural catastrophe risk,indicating that the mechanism of administrative remedy has the greatest efficiency and highest cost;the mechanism of social assistance has the lowest cost,but its efficiency is lowest and there are unstable factors;market mechanism,namely the insurance of agricultural catastrophe,is the rational choice of agricultural department in mechanism of risk spreading.This paper analyzes the status quo of China’s insurance of agricultural catastrophe,indicating that the main body of management in China’s insurance of agricultural catastrophe is missing.In addition,the market demand is critically scanty,and insurance of agricultural catastrophe lacks external development environment.The gap of China’s insurance law of agricultural catastrophe has become the greatest obstacle to the development of insurance of agricultural catastrophe.From legislative purpose,basic principle,nature,main body of legal relations,management range,policy support,supervision and management and so on,the legislation conception of China’s insurance of agricultural catastrophe is put forward.

  20. Pain Catastrophizing and Its Relationship with Health Outcomes: Does Pain Intensity Matter?

    Science.gov (United States)

    García-Palacios, Azucena; Botella, Cristina; Ribera-Canudas, Maria Victoria

    2017-01-01

    Pain catastrophizing is known to contribute to physical and mental functioning, even when controlling for the effect of pain intensity. However, research has yet to explore whether the strength of the relationship between pain catastrophizing and pain-related outcomes varies across pain intensity levels (i.e., moderation). If this was the case, it would have important implications for existing models of pain and current interventions. The present investigation explored whether pain intensity moderates the relationship between pain catastrophizing and pain-related outcomes. Participants were 254 patients (62% women) with heterogeneous chronic pain. Patients completed a measure of pain intensity, pain interference, pain catastrophizing, and physical and mental health. Pain intensity moderated the relationship between pain catastrophizing and pain interference and between pain catastrophizing and physical health status. Specifically, the strength of the correlation between pain catastrophizing and these outcomes decreased considerably as pain intensity increased. In contrast, pain intensity did not moderate the relationship between pain catastrophizing and mental health. Study findings provide a new insight into the role of pain intensity (i.e., moderator) in the relationship between pain catastrophizing and various pain-related outcomes, which might help develop existent models of pain. Clinical implications are discussed in the context of personalized therapy.

  1. Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations (I): catastrophic APS, APS nephropathy and heart valve lesions.

    Science.gov (United States)

    Cervera, R; Tektonidou, M G; Espinosa, G; Cabral, A R; González, E B; Erkan, D; Vadya, S; Adrogué, H E; Solomon, M; Zandman-Goddard, G; Shoenfeld, Y

    2011-02-01

    The objectives of the 'Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations' were to assess the clinical utility of the international consensus statement on classification criteria and treatment guidelines for the catastrophic APS, to identify and grade the studies that analyse the relationship between the antiphospholipid antibodies and the non-criteria APS manifestations and to present the current evidence regarding the accuracy of these non-criteria APS manifestations for the detection of patients with APS. This article summarizes the studies analysed on the catastrophic APS, APS nephropathy and heart valve lesions, and presents the recommendations elaborated by the Task Force after this analysis.

  2. The effectiveness of the nationwide BokSmart rugby injury prevention program on catastrophic injury rates.

    Science.gov (United States)

    Brown, J C; Verhagen, E; Knol, D; Van Mechelen, W; Lambert, M I

    2016-02-01

    Rugby Union ("rugby") participants have a higher than average risk of injury compared with participants of other popular team sports. BokSmart, a nationwide injury prevention program was launched in South Africa in mid-2009, with the goal of reducing catastrophic head/neck (serious) injuries in players. The program provides injury prevention information to coaches and referees. This study investigated if BokSmart has been associated with a reduction in these injuries. The BokSmart program collected data on all South African rugby-related serious injuries since 2008. Using a Poisson regression, injury numbers were compared pre-BokSmart (2008-2009) to the years post-implementation (2010-2013). Player numbers were assumed to be constant throughout this evaluation: junior = 529,483; senior = 121,663. In junior players, the "post-BokSmart" period had 2.5 less annual serious injuries than "pre-BokSmart" (incidence rate ratio: 0.6, 95% confidence interval: 0.5-0.7, P < 0.000). In contrast, there was no significant difference in these periods in seniors. The absence of effect in seniors may be a result of fewer players or of differences in effectiveness of BokSmart in this group--future studies should investigate these questions.

  3. Cancer incidence among waiters

    DEFF Research Database (Denmark)

    Reijula, Jere; Kjaerheim, Kristina; Lynge, Elsebeth

    2015-01-01

    INCIDENCE IN SOME CANCER SITES CAN LIKELY BE EXPLAINED BY HIGHER ALCOHOL CONSUMPTION, THE PREVALENCE OF SMOKING AND OCCUPATIONAL EXPOSURE TO TOBACCO SMOKE HOPEFULLY, THE INCIDENCE OF CANCER AMONG WAITERS WILL DECREASE IN THE FUTURE, DUE TO THE BANNING OF TOBACCO SMOKING IN RESTAURANTS AND BARS IN THE NORDIC...

  4. A ground moving target emergency tracking method for catastrophe rescue

    Science.gov (United States)

    Zhou, X.; Li, D.; Li, G.

    2014-11-01

    In recent years, great disasters happen now and then. Disaster management test the emergency operation ability of the government and society all over the world. Immediately after the occurrence of a great disaster (e.g., earthquake), a massive nationwide rescue and relief operation need to be kicked off instantly. In order to improve the organizations efficiency of the emergency rescue, the organizers need to take charge of the information of the rescuer teams, including the real time location, the equipment with the team, the technical skills of the rescuers, and so on. One of the key factors for the success of emergency operations is the real time location of the rescuers dynamically. Real time tracking methods are used to track the professional rescuer teams now. But volunteers' participation play more and more important roles in great disasters. However, real time tracking of the volunteers will cause many problems, e.g., privacy leakage, expensive data consumption, etc. These problems may reduce the enthusiasm of volunteers' participation for catastrophe rescue. In fact, the great disaster is just small probability event, it is not necessary to track the volunteers (even rescuer teams) every time every day. In order to solve this problem, a ground moving target emergency tracking method for catastrophe rescue is presented in this paper. In this method, the handheld devices using GPS technology to provide the location of the users, e.g., smart phone, is used as the positioning equipment; an emergency tracking information database including the ID of the ground moving target (including the rescuer teams and volunteers), the communication number of the handheld devices with the moving target, and the usually living region, etc., is built in advance by registration; when catastrophe happens, the ground moving targets that living close to the disaster area will be filtered by the usually living region; then the activation short message will be sent to the selected

  5. Social cognitive theory of posttraumatic recovery: the role of perceived self-efficacy.

    Science.gov (United States)

    Benight, Charles C; Bandura, Albert

    2004-10-01

    The present article integrates findings from diverse studies on the generalized role of perceived coping self-efficacy in recovery from different types of traumatic experiences. They include natural disasters, technological catastrophes, terrorist attacks, military combat, and sexual and criminal assaults. The various studies apply multiple controls for diverse sets of potential contributors to posttraumatic recovery. In these different multivariate analyses, perceived coping self-efficacy emerges as a focal mediator of posttraumatic recovery. Verification of its independent contribution to posttraumatic recovery across a wide range of traumas lends support to the centrality of the enabling and protective function of belief in one's capability to exercise some measure of control over traumatic adversity.

  6. Critical Amount of Resource in Containing Catastrophic Epidemics

    CERN Document Server

    Chen, Xiaolong; Feng, Ling; Yang, Chun; Wang, Moming; Fan, Xiaoming; Hu, Yanqing

    2016-01-01

    During an epidemic control, the containment of the disease is usually achieved through increasing public health resource to quickly identify, quarantine and cure the infected population. However, the exact impact of this resource expenditure on the physical spreading dynamics remains unknown. In this work we find that the influence of resource expenditure exhibits extreme critical behaviour, which is the first order phase transition in nature. Specifically, if the amount of invested resource is below a critical value, a significant fraction of the total population will become infected; once it is more than that critical value, the disease outbreak can be effectively eradicated or contained. This finding implies that the government expenditure on infectious disease control needs to meet a certain critical threshold to be of any effectiveness. Otherwise, the outbreak could be catastrophic. We have validated our theoretical results on one real contact network and three typical social networks, with all of them e...

  7. Catastrophes in nature and society mathematical modeling of complex systems

    CERN Document Server

    Khlebopros, Rem G; Fet, Abram I

    2007-01-01

    Many people are concerned about crises leading to disasters in nature, in social and economic life. The book offers a popular account of the causative mechanisms of critical states and breakdown in a broad range of natural and cultural systems - which obey the same laws - and thus makes the reader aware of the origin of catastrophic events and the ways to avoid and mitigate their negative consequences. The authors apply a single mathematical approach to investigate the revolt of cancer cells that destroy living organisms and population outbreaks that upset natural ecosystems, the balance between biosphere and global climate interfered lately by industry, the driving mechanisms of market and related economic and social phenomena, as well as the electoral system the proper use of which is an arduous accomplishment of democracy.

  8. Rotation-Dependent Catastrophic Disruption of Gravitational Aggregates

    CERN Document Server

    Ballouz, Ronald-Louis; Michel, Patrick; Schwartz, Stephen R

    2014-01-01

    We carry out a systematic exploration of the effect of pre-impact rotation on the outcomes of low-speed collisions between planetesimals modeled as gravitational aggregates. We use pkdgrav, a cosmology code adapted to collisional problems and recently enhanced with a new soft-sphere collision algorithm that includes more realistic contact forces. A rotating body has lower effective surface gravity than a non-rotating one and therefore might suffer more mass loss as the result of a collision. What is less well understood, however, is whether rotation systematically increases mass loss on average regardless of the impact trajectory. This has important implications for the efficiency of planet formation via planetesimal growth, and also more generally for the determination of the impact energy threshold for catastrophic disruption (leading to the largest remnant retaining 50% of the original mass), as this has generally only been evaluated for non-spinning bodies. We find that for most collision scenarios, rotat...

  9. Catastrophic Antiphospholipid Syndrome Presenting as Bilateral Central Retinal Artery Occlusions

    Directory of Open Access Journals (Sweden)

    Steven S. Saraf

    2015-01-01

    Full Text Available A previously healthy 22-year-old African American woman presented with bilateral vision loss associated with headache. Her ocular examination was significant for bilateral retinal arterial “boxcarring,” retinal whitening, retinal hemorrhages, and cherry red spots. She was diagnosed with bilateral central retinal artery occlusions and was hospitalized due to concomitant diagnosis of stroke and hypercoagulable state. She was also found to be in heart failure and kidney failure. Rheumatology was consulted and she was diagnosed with catastrophic antiphospholipid syndrome in association with systemic lupus erythematosus. Approximately 7 months after presentation, the patient’s vision improved and remained stable at 20/200 and 20/80.

  10. Catastrophe characteristics of the condensation and pool boiling phenomena

    Science.gov (United States)

    Ma, Xuehu; Xu, Dunqi; Lin, Jifang

    1995-02-01

    Recently, Utaka proposed two types of the transition modes of dropwise condensation, i.e. the continuous and the jumping modes, and presented a criterion for determining the condensation transition mode. Stylianous and Rose proposed two hypotheses, the coalescence-limited transition and the nucleation site saturation transition. Neither Utaka's criterion nor Rose's hypotheses could clearly interpret the physical mechanisms of the transition both from filmwise to dropwise and from dropwise to pseudofilm condensation, and explicitly presented the main factors affecting the transitions. Kalinin hs given a general review of the transition boiling heat transfer. The catastrophe theory will be applied here to eluicidate the complex phenomena of the transitions of the condensation and boiling pattern states.

  11. Can non-ideal magnetohydrodynamics solve the magnetic braking catastrophe?

    CERN Document Server

    Wurster, James; Bate, Matthew R

    2015-01-01

    We investigate whether or not the low ionisation fractions in molecular cloud cores can solve the `magnetic braking catastrophe', where magnetic fields prevent the formation of circumstellar discs around young stars. We perform three-dimensional smoothed particle non-ideal magnetohydrodynamics (MHD) simulations of the gravitational collapse of one solar mass molecular cloud cores, incorporating the effects of ambipolar diffusion, Ohmic resistivity and the Hall effect alongside a self-consistent calculation of the ionisation chemistry assuming 0.1 micron grains. When including only ambipolar diffusion or Ohmic resistivity, discs do not form in the presence of strong magnetic fields, similar to the cases using ideal MHD. With the Hall effect included, disc formation depends on the direction of the magnetic field with respect to the rotation vector of the gas cloud. When the vectors are aligned, strong magnetic braking occurs and no disc is formed. When the vectors are anti-aligned, a disc with radius of 13AU ca...

  12. Chasma Australe Mars: Structural Framework for a Catastrophic Outflow Origin

    Science.gov (United States)

    Anguita, F.; Babin, R.; Benito, G.; Collado, A.; Gomez, D.; Rice, J. W.

    1998-01-01

    Chasma Australe is the most remarkable of the martian south pole erosional reentrants carved in the polar layered deposits. Ms chasma originates near the south pole and runs across the polar troughs over a distance of about 500 km. Its width varies between 20 and 80 km and, with a depth up to 1000 m, it reaches the bedrock. Following an idea put forward originally for Chasma Boreale, we propose for the genesis of Chasma Australe a mechanism of catastrophic outflow preceded by a tectonically induced powerful sapping process. A detailed geomorphological analysis of Chasma Australe shows erosional and depositional features that can be interpreted as produced by the motion of a fluid. Like other polar reentrants, Chasma Australe is clearly assymetric, with a steep eastern margin where basal and lateral erosion prevailed, and a gentler western side, where the stepped topography and bedrock spurs favored deposition.

  13. Eradicating Catastrophic Collapse in Interdependent Networks via Reinforced Nodes

    CERN Document Server

    Yuan, Xin; Stanley, H Eugene; Havlin, Shlomo

    2016-01-01

    In interdependent networks, it is usually assumed, based on percolation theory, that nodes become nonfunctional if they lose connection to the network giant component. However, in reality, some nodes, equipped with alternative resources, together with their connected neighbors can still be functioning once disconnected from the giant component. Here we propose and study a generalized percolation model that introduces a fraction of reinforced nodes in the interdependent networks that can function and support their neighborhood. We analyze, both analytically and via simulations, the order parameter$-$the functioning component$-$comprising both the giant component and smaller components that include at least one reinforced node. Remarkably, we find that for interdependent networks, we need to reinforce only a small fraction of nodes to prevent abrupt catastrophic collapses. Moreover, we find that the universal upper bound of this fraction is 0.1756 for two interdependent Erd\\H{o}s-R\\'{e}nyi (ER) networks, regula...

  14. The role of infectious diseases in the catastrophic antiphospholipid syndrome.

    Science.gov (United States)

    Garcia-Carrasco, M; Mendoza-Pinto, C; Macias-Diaz, S; Vazquez de Lara, F; Etchegaray-Morales, I; Galvez-Romero, J L; Mendez-Martinez, S; Cervera, R

    2015-11-01

    Catastrophic antiphospholipid syndrome (CAPS), also called "Asherson syndrome", is a variant of the antiphospholipid syndrome (APS) that occurs in less than 1% of APS cases. The etiology of CAPS is uncertain; however, several triggering factors have been recognized. The most common of these are infectious diseases, particularly those of the respiratory tract. CAPS pathogenesis is incompletely understood, but several theories have been proposed, such as the molecular mimicry theory, which describes the production of anti-β2-glycoprotein I (GP1) antibody in response to infection. The process is complex and involves the activation of Toll-like receptor 4 (TLR-4), which triggers a cytokine storm, followed by endothelial alterations that induce a procoagulant state.

  15. Heckling the Catastrophe. On the Holocaust Literary Criticism

    Directory of Open Access Journals (Sweden)

    Paweł Wolski

    2015-01-01

    Full Text Available The article discusses a special kind of narrative about the catastrophe, treated as a specific genre of writing: the theory of literature of the Holocaust. The article presents its two most significant (although not the only ones features: firstly, the conviction about its unusual character as compared to other genres/forms of writing, sometimes secretly described by such concepts as the uniqueness of the Holocaust (which metonymizes not only the event itself but also the narrations referring to it and, secondly, identifies all text-producing entities (narrator, author etc., simultaneously constituting the basic feature of the most important genre/modality of this kind of writing which is testimony. The article presents the examples of Polish and foreign scholars portraying this state of affairs.

  16. MECHANISM AND CATASTROPHE THEORY ANALYSIS OF CIRCULAR TUNNEL ROCKBURST

    Institute of Scientific and Technical Information of China (English)

    PAN Yue; ZHANG Yong; YU Guang-ming

    2006-01-01

    Mechanism of circular tunnel rockburst is that, when the carrying capacity of the centralized zone of plastic deformation in limiting state reduces, the comparatively intact part in rock mass unloads by way of elasticity; rockburst occurs immediately when the elastic energy released by the comparatively intact part exceeds the energy dissipated by plastic deformation. The equivalent strain was taken as a state variable to establish a catastrophe model of tunnel rockburst, and the computation expression of the earthquake energy released by tunnel rockburst was given. The analysis shows that, the conditions of rockburst occurrence are relative to rock's ratio of elastic modulus to descendent modulus and crack growth degree of rocks; to rock mass with specific rockburst tendency, there exists a corresponding critical depth of softened zone, and rockburst occurs when the depth of softened zone reaches.

  17. Catastrophe analysis on pillar instability considered mining effect

    Institute of Scientific and Technical Information of China (English)

    LI Jiang-teng; CAO Ping

    2005-01-01

    The instability of the pillar was discussed based on the potential energy principle and the cusp catastrophe theory, and a simplified mechanical model of the pillar was established considering the mining effect. The necessary-sufficient conditions, the jump value of displacement of pillar and the released energy expressions were deduced. The results show that the instability of the pillar is related to the properties of the rock, the external force and the relative stiffness of the elastic area to the plastic area. The instability of system is like to occur with the enlarging of the softening area or the decreasing of E/λ. The calculation done shows that the estimated results correspond to practical experience.

  18. Stability of theoretical model for catastrophic weather prediction

    Institute of Scientific and Technical Information of China (English)

    SHI Wei-hui; WANG Yue-peng

    2007-01-01

    Stability related to theoretical model for catastrophic weather prediction,which includes non-hydrostatic perfect elastic model and anelastic model, is discussed and analyzed in detail. It is proved that non-hydrostatic perfect elastic equations set is stable in the class of infinitely differentiable function. However, for the anelastic equations set, its continuity equation is changed in form because of the particular hypothesis for fluid, so "the matching consisting of both viscosity coefficient and incompressible assumption" appears, thereby the most important equations set of this class in practical prediction shows the same instability in topological property as Navier-Stokes equation,which should be avoided first in practical numerical prediction. In light of this, the referenced suggestions to amend the applied model are finally presented.

  19. Variable Structure Control of Catastrophic Course in Airdropping Heavy Cargo

    Institute of Scientific and Technical Information of China (English)

    Zhang Huiyuan; Shi Zhongke

    2009-01-01

    The mathematical model of a transport aircraft would be subjected to a sudden change when heavy cargo is dropped off in airdropping, which exerts serious influences upon the safety of the aircraft. A variable structure controller is specially designed for handling the airdrop process. The nonlinear system is linearized by input-output feedback linearization using differential geometry theories. On this basis, an inner loop system for velocity and attitude tracking control is designed by using the exponentially approaching rule of the variable structure theory. The whole flight control system is integrated with the outer loop flight altitude control. Digital simulation evidences the applicability of the system to potentially catastrophic course in airdropping heavy cargo and provides robustness against system parameter perturbation.

  20. Catastrophe Insurance Modeled by Shot-Noise Processes

    Directory of Open Access Journals (Sweden)

    Thorsten Schmidt

    2014-02-01

    Full Text Available Shot-noise processes generalize compound Poisson processes in the following way: a jump (the shot is followed by a decline (noise. This constitutes a useful model for insurance claims in many circumstances; claims due to natural disasters or self-exciting processes exhibit similar features. We give a general account of shot-noise processes with time-inhomogeneous drivers inspired by recent results in credit risk. Moreover, we derive a number of useful results for modeling and pricing with shot-noise processes. Besides this, we obtain some highly tractable examples and constitute a useful modeling tool for dynamic claims processes. The results can in particular be used for pricing Catastrophe Bonds (CAT bonds, a traded risk-linked security. Additionally, current results regarding the estimation of shot-noise processes are reviewed.

  1. Coupled catastrophes: sudden shifts cascade and hop among interdependent systems

    CERN Document Server

    Brummitt, Charles D; D'Souza, Raissa M

    2014-01-01

    A profoundly important challenge in several disciplines today is to understand how sudden changes can propagate among coupled systems. Examples include the synchronization of business cycles, population collapse in patchy ecosystems, markets shifting to a new technology platform, collapses in prices and in confidence in financial markets, and protests erupting in multiple countries. We characterize these phenomena using a simple model grounded in the theory of fast--slow ordinary differential equations and in catastrophe theory. In the model, a system consists of multiple subsystems (e.g., countries in the global economy or patches of an ecosystem), each described by a scalar quantity (such as economic output or population) that undergoes sudden changes via saddle-node bifurcations. The subsystems are coupled via their scalar quantities (e.g., trade couples economic output, diffusion couples populations); that coupling moves their bifurcations. The model elucidates two ways in which sudden changes can propaga...

  2. On the governance of global and catastrophic risks

    DEFF Research Database (Denmark)

    Faber, Michael Havbro

    2011-01-01

    of sustainable and global life safety and health improvements? Finally, new results and perspectives are presented on the issue of allocation of resources for the purpose of improving global public health and a discussion on global risk governance concludes the paper.......The focus of the present paper regards the identification and treatment of critical issues in the process of societal decision making concerning management of global and catastrophic risks. Taking basis in recent works by the author, the paper in particular addresses: 1) Which are the most relevant...... hazards in a holistic global perspective and how may these be categorised in view of strategies for their treatment?; 2) How might robust societal decisions on risk management subject to large uncertainties be formally supported?; 3) How may available economic resources be prioritised for the purpose...

  3. Alternative solutions for public and private catastrophe funding in Austria

    Directory of Open Access Journals (Sweden)

    M. Gruber

    2008-07-01

    Full Text Available The impacts of natural hazards as well as their frequency of occurrence during the last decades have increased decisively. Therefore, the public as well as the private sector are expected to react to this development by providing sufficient funds, in particular for the improvement of protection measures and an enhanced funding of damage compensation for affected private individuals, corporate and public entities.

    From the public stance, the establishment of an appropriate regulatory environment seems to be indispensable. Structural and legal changes should, on the one hand, renew and improve the current distribution system of public catastrophe funds as well as the profitable investment of these financial resources, and on the other hand, facilitate the application of alternative mechanisms provided by the capital and insurance markets.

    In particular, capital markets have developed alternative risk transfer and financing mechanisms, such as captive insurance companies, risk pooling, contingent capital solutions, multi-trigger products and insurance securitisation for hard insurance market phases. These instruments have already been applied to catastrophic (re-insurance in other countries (mainly the US and off-shore domiciles, and may contribute positively to the insurability of extreme weather events in Austria by enhancing financial capacities. Not only private individuals and corporate entities may use alternative mechanisms in order to retain, thus, to finance certain risks, but also public institutions.

    This contribution aims at analysing potential solutions for an improved risk management of natural hazards in the private and the public sector by considering alternative mechanisms of the capital and insurance markets. Also the establishment of public-private-partnerships, which may contribute to a more efficient cat funding system in Austria, is considered.

  4. Overcoming challenges of catastrophe modelling in data poor regions

    Science.gov (United States)

    Grassby, L.; Millinship, I.; Breinl, K.

    2012-04-01

    There is an increasing demand for loss accumulation tools in expanding international insurance markets such as India, China and Thailand. This reflects the combination of an increase in exposures in these territories as industry intensifies and urban development expands, as well as several notable natural catastrophes affecting these areas over the past few years (e.g. extreme floods in Mumbai in 2006 and in Thailand in 2011). Large, global insurers and reinsurers are embracing the opportunity to underwrite these exposures but only where adequate tools are available to provide understanding of the hazards, exposures and potential losses. Unlike more developed countries, data availability in these regions is typically limited and of poor resolution, but model development is still required in order to analyse the risk. Some of the modelling challenges associated with data limitations include: (1) dealing with a lack of hydrological data which results in greater uncertainty of the flow rate and event frequency; (2) lower DTM resolution than that available across much of Europe, which underlies the hazard component of the catastrophe model; (3) limited accessibility to data that characterises the Built Environment including information on different building types and their susceptibility to damage; and (4) a lack of claims data from previous events or engineering research into the vulnerability of different building types. This is used to generate of country and structure specific vulnerability curves that explain the relationship between hazard intensity and damages. By presenting an industry specific flood model for data-poor India in collaboration with Allianz Re, we illustrate how we have overcome many of these challenges to allow loss accumulations to be made. The resulting model was successfully validated against the floods in Mumbai and Surat in 2006 and is being developed further with the availability of new data.

  5. Dynamic growth of slip surfaces in catastrophic landslides.

    Science.gov (United States)

    Germanovich, Leonid N; Kim, Sihyun; Puzrin, Alexander M

    2016-01-01

    This work considers a landslide caused by the shear band that emerges along the potential slip (rupture) surface. The material above the band slides downwards, causing the band to grow along the slope. This growth may first be stable (progressive), but eventually becomes dynamic (catastrophic). The landslide body acquires a finite velocity before it separates from the substrata. The corresponding initial-boundary value problem for a dynamic shear band is formulated within the framework of Palmer & Rice's (Proc. R. Soc. Lond. A332, 527-548. (doi:10.1098/rspa.1973.0040)) approach, which is generalized to the dynamic case. We obtain the exact, closed-form solution for the band velocity and slip rate. This solution assesses when the slope fails owing to a limiting condition near the propagating tip of the shear band. Our results are applicable to both submarine and subaerial landslides of this type. It appears that neglecting dynamic (inertia) effects can lead to a significant underestimation of the slide size, and that the volumes of catastrophic slides can exceed the volumes of progressive slides by nearly a factor of 2. As examples, we consider the Gaviota and Humboldt slides offshore of California, and discuss landslides in normally consolidated sediments and sensitive clays. In particular, it is conceivable that Humboldt slide is unfinished and may still displace a large volume of sediments, which could generate a considerable tsunami. We show that in the case of submarine slides, the effect of water resistance on the shear band dynamics may frequently be limited during the slope failure stage. For a varying slope angle, we formulate a condition of slide cessation.

  6. Alternative solutions for public and private catastrophe funding in Austria

    Science.gov (United States)

    Gruber, M.

    2008-07-01

    The impacts of natural hazards as well as their frequency of occurrence during the last decades have increased decisively. Therefore, the public as well as the private sector are expected to react to this development by providing sufficient funds, in particular for the improvement of protection measures and an enhanced funding of damage compensation for affected private individuals, corporate and public entities. From the public stance, the establishment of an appropriate regulatory environment seems to be indispensable. Structural and legal changes should, on the one hand, renew and improve the current distribution system of public catastrophe funds as well as the profitable investment of these financial resources, and on the other hand, facilitate the application of alternative mechanisms provided by the capital and insurance markets. In particular, capital markets have developed alternative risk transfer and financing mechanisms, such as captive insurance companies, risk pooling, contingent capital solutions, multi-trigger products and insurance securitisation for hard insurance market phases. These instruments have already been applied to catastrophic (re-)insurance in other countries (mainly the US and off-shore domiciles), and may contribute positively to the insurability of extreme weather events in Austria by enhancing financial capacities. Not only private individuals and corporate entities may use alternative mechanisms in order to retain, thus, to finance certain risks, but also public institutions. This contribution aims at analysing potential solutions for an improved risk management of natural hazards in the private and the public sector by considering alternative mechanisms of the capital and insurance markets. Also the establishment of public-private-partnerships, which may contribute to a more efficient cat funding system in Austria, is considered.

  7. Key Planning Factors for Recovery from a Biological Terrorism Incident

    Science.gov (United States)

    2012-08-30

    goals may be advised for areas where young children or people with compromised immune systems spend considerable time. Pre-planning for clearance...Cipro) can cause moderate to severe nausea, diarrhea , vomiting, headache, stomach pain, skin rashes, mental confusion, tremors, seizures

  8. Research on traffic flow forecasting model based on cusp catastrophe theory

    Institute of Scientific and Technical Information of China (English)

    张亚平; 裴玉龙

    2004-01-01

    This paper intends to describe the relationship between traffic parameters by using cusp catastrophe theory and to deduce highway capacity and corresponding speed forecasting value through suitable transformation of catastrophe model. The five properties of a catastrophe system are outlined briefly, and then the data collected on freeways of Zhujiang River Delta, Guangdong province, China are examined to ascertain whether they exhibit qualitative properties and attributes of the catastrophe model. The forecasting value of speed and capacity for freeway segments are given based on the catastrophe model. Furthermore, speed-flow curve on freeway is drawn by plotting out congested and uncongested traffic flow and the capacity value for the same freeway segment is also obtained from speed-flow curve to test the feasibility of the application of cusp catastrophe theory in traffic flow analysis. The calculating results of catastrophe model coincide with those of traditional traffic flow models regressed from field observed data, which indicates that the deficiency of traditional analysis of relationship between speed, flow and occupancy in two-dimension can be compensated by analysis of the relationship among speed, flow and occupancy based on catastrophe model in three-dimension. Finally, the prospects and problems of its application in traffic flow research in China are discussed.

  9. Spatial structure induced by marine reserves shapes population responses to catastrophes in mathematical models.

    Science.gov (United States)

    McGilliard, Carey R; Punt, André E; Hilborn, Ray

    2011-06-01

    Catastrophic events such as oil spills, hypoxia, disease, and major predation events occur in marine ecosystems and affect fish populations. Previous evaluations of the performance of spatial management alternatives have not considered catastrophic events. We investigate the effects of local and global catastrophic events on populations managed with and without no-take marine reserves and with fishing mortality rates that are optimized accounting for reserves. A spatial population dynamics model is used to explore effects of large, catastrophic natural mortality events. The effects of the spatial spread, magnitude, probability of catastrophe, and persistence of a catastrophic event through time are explored. Catastrophic events affecting large spatial areas and those that persist through time have the greatest effects on population dynamics because they affect natural mortality nonlinearly, whereas the probability and magnitude of catastrophic events result in only linear increases in natural mortality. The probability of falling below 10% or 20% of unfished abundance was greatest when a no-take marine reserve was implemented with no additional fishing regulations and least when a no-take marine reserve was implemented in addition to the maintenance of optimal fishing mortality in fished areas. In the absence of implementation error, maintaining abundance across space using restrictions on fishing mortality rates, regardless of the existence of a no-take marine reserve, decreased the probability of falling below 10% or 20% of unfished abundance.

  10. Analysis of Interlayer Connection Catastrophe Characteristics in Internet AS level Topology

    Directory of Open Access Journals (Sweden)

    Si-yuan Jia

    2013-02-01

    Full Text Available Based on CAIDA’s (cooperative association for Internet data analysis statistics at AS-level collected from April 2009 to April 2010, it is found that network size, degree correlations and clustering have changed significantly three times. According to the definition of k-core, the Internet topology is divided into different levels. In this paper, by analyzing the changing connection on each level at the three time spots, we found that the connection difference between the highest and the lowest level varies cyclically. Before Internet has significant change, the connection difference between the highest and the lowest shell changes acutely. At that time point it is the later stage of the fluctuation period which is the accumulation of small fluctuation. The concept of catastrophe coefficient is proposed for quantifying the probability of Internet catastrophe so that the catastrophe coefficient of Internet could be calculated on real time, and the catastrophe time spots could be predicted. Using real data for verification, it turns out that catastrophe coefficient can accurately predict the "giant fluctuations" occurrence in the macroscopic structure. With the proposal of the concept of catastrophe coefficient, the research can play an important guiding role in understanding the actual network internal development and changes, analyzing the cause of Internet catastrophe, preventing devastating catastrophe, planning and further re-designing Ipv6.

  11. Applying Catastrophe Theory to an Information-Processing Model of Problem Solving in Science Education

    Science.gov (United States)

    Stamovlasis, Dimitrios; Tsaparlis, Georgios

    2012-01-01

    In this study, we test an information-processing model (IPM) of problem solving in science education, namely the working memory overload model, by applying catastrophe theory. Changes in students' achievement were modeled as discontinuities within a cusp catastrophe model, where working memory capacity was implemented as asymmetry and the degree…

  12. 12 CFR 741.214 - Report of crime or catastrophic act and Bank Secrecy Act compliance.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Report of crime or catastrophic act and Bank Secrecy Act compliance. 741.214 Section 741.214 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION... Unions § 741.214 Report of crime or catastrophic act and Bank Secrecy Act compliance. Any credit...

  13. Pain-related catastrophizing in pain patients and people with pain in the general population

    NARCIS (Netherlands)

    de Boer, M. J.; Struys, M. M. R. F.; Versteegen, G. J.

    2012-01-01

    Background Catastrophizing is a defining factor in the pain experience and strongly contributes to the prediction of various aspects of health. Catastrophizing is not just present in pain patients, but may also be present in people with non-clinical pain. The aim of the present study is to investiga

  14. Pain-related catastrophizing in pain patients and people with pain in the general population.

    NARCIS (Netherlands)

    Boer, M.J. de; Struys, M.M.; Versteegen, G.J.

    2012-01-01

    BACKGROUND: Catastrophizing is a defining factor in the pain experience and strongly contributes to the prediction of various aspects of health. Catastrophizing is not just present in pain patients, but may also be present in people with non-clinical pain. The aim of the present study is to investig

  15. Gérard Brugnot, 2008, Les Catastrophes Naturelles, Paris, Le Cavalier Bleu, 127 p.

    Directory of Open Access Journals (Sweden)

    Stéphane Callens

    2009-01-01

    Full Text Available La collection « idées reçues » se propose de faire le point sur les savoirs et les croyances à propos d’un thème donné. Le thème des « catastrophes naturelles » est présenté par Gérard Brugnot, qui commente 16 idées reçues sur ces risques majeurs, regroupées dans quatre chapitres : 1/ « il y a toujours eu des catastrophes naturelles, il y en aura toujours », 2/ « Des catastrophes vraiment toutes naturelles ? », 3/ « On peut réduire les effets des catastrophes naturelles », 4/ « Catastrophes n...

  16. Yoga attitudes in chronic low back pain: Roles of catastrophizing and fear of movement.

    Science.gov (United States)

    Combs, Martha A; Thorn, Beverly E

    2015-08-01

    Chronic low back pain is a significant public health problem and, although underused, yoga may be an effective complementary treatment. The current study examined associations of pain catastrophizing and fear of movement with attitudes toward yoga in adults with chronic low back pain. Participants completed three quantitative questionnaires assessing specific constructs: beliefs about yoga, fear of movement, and pain catastrophizing. A semi-structured in-person interview was then conducted to obtain specific pain-related information. Hierarchical regression and mediational analyses were used to test hypotheses. Consistent with the fear-avoidance model of chronic pain, catastrophizing and fear of movement were negatively associated with yoga attitudes. Specifically, fear of movement was a mediator between catastrophizing and attitudes toward yoga. Individuals with higher levels of catastrophizing and fear of movement may be less likely to consider a pain treatment involving physical movement.

  17. Precursory landforms and geologic structures of catastrophic landslides induced by typhoon Talas 2011 Japan (Invited)

    Science.gov (United States)

    Chigira, M.; Matsushi, Y.; Tsou, C.

    2013-12-01

    Our experience of catastrophic landslides induced by rainstorms and earthquakes in recent years suggests that many of them are preceded by deep-seated gravitational slope deformation. Deep-seated gravitational slope deformation continues slowly and continually and some of them transform into catastrophic failures, which cause devastating damage in wide areas. Some other types, however, do not change into catastrophic failure. Deep-seated gravitational slope deformation that preceded catastrophic failures induced by typhoon Talas 2011 Japan, had been surveyed with airborne laser scanner beforehand, of which high-resolution DEMs gave us an important clue to identify which type of topographic features of gravitational slope deformation is susceptible to catastrophic failure. We found that 26 of 39 deep-seated catastrophic landslides had small scarps along the heads of future landslides. These scarps were caused by gravitational slope deformation that preceded the catastrophic failure. Although the scarps may have been enlarged by degradation, their sizes relative to the whole slopes suggest that minimal slope deformation had occurred in the period immediately before the catastrophic failure. The scarp ratio, defined as the ratio of length of a scarp to that of the whole slope both measured along the slope line, ranged from 1% to 23%. 38% of the landslides with small scarps had scarp ratios less than 4%, and a half less than 8%. This fact suggests that the gravitational slope deformation preceded catastrophic failure was relatively small and may suggest that those slopes were under critical conditions just before catastrophic failure. The above scarp ratios may be characteristic to accretional complex with undulating, anastomosing thrust faults, which were major sliding surfaces of the typhoon-induced landslides. Eleven of the remaining 13 landslides occurred in landslide scars of previous landslides or occurred as an extension of landslide scars at the lower parts of

  18. Drug related critical incidents.

    Science.gov (United States)

    Khan, F A; Hoda, M Q

    2005-01-01

    Drug related incidents are a common form of reported medical errors. This paper reviews the critical incidents related to drug errors reported from the main operating theatre suite in a teaching hospital in a developing country from January 1997 to December 2002. Each report was evaluated individually by two reviewers using a structured process. During this period, 44 874 anaesthetics were administered; 768 critical incidents were reported, 165 (21%) of which were related to drug errors. Underdosage, side-effect/drug reaction and syringe swap were the most common. A total of 76% were classified as preventable; 56% due to human error and 19% due to system error. High risk incidents accounted for 10% of all drug errors and most of these were related to the use of neuromuscular blocking drugs. This analysis has been found useful in addressing some issues about priorities.

  19. Large whale incident database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Large whale stranding, death, ship strike and entanglement incidents are all recorded to monitor the health of each population and track anthropogenic factors that...

  20. Police Incident Blotter (Archive)

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The Police Blotter Archive contains crime incident data after it has been validated and processed to meet Uniform Crime Reporting (UCR) standards, published on a...

  1. The critical incident inventory: characteristics of incidents which affect emergency medical technicians and paramedics

    Directory of Open Access Journals (Sweden)

    Halpern Janice

    2012-08-01

    Full Text Available Abstract Background Emergency medical technicians (EMTs and paramedics experience critical incidents which evoke distress and impaired functioning but it is unknown which aspects of incidents contribute to their impact. We sought to determine these specific characteristics by developing an inventory of critical incident characteristics and testing their relationship to protracted recovery from acute stress, and subsequent emotional symptoms. Methods EMT/paramedics (n = 223 completed a retrospective survey of reactions to an index critical incident, and current depressive, posttraumatic and burnout symptoms. Thirty-six potential event characteristics were evaluated; 22 were associated with peritraumatic distress and were retained. We assigned inventory items to one of three domains: situational, systemic or personal characteristics. We tested the relationships between (a endorsing any domain item and (b outcomes of the critical incident (peritraumatic dissociation, recovery from components of the Acute Stress Reaction and depressive, posttraumatic, and burnout symptoms. Analyses were repeated for the number of items endorsed. Results Personal and situational characteristics were most frequently endorsed. The personal domain had the strongest associations, particularly with peritraumatic dissociation, prolonged distressing feelings, and current posttraumatic symptoms. The situational domain was associated with peritraumatic dissociation, prolonged social withdrawal, and current posttraumatic symptoms. The systemic domain was associated with peritraumatic dissociation and prolonged irritability. Endorsing multiple characteristics was related to peritraumatic, acute stress, and current posttraumatic symptoms. Relationships with outcome variables were as strong for a 14-item inventory (situational and personal characteristics only as the 22-item inventory. Conclusions Emotional sequelae are associated most strongly with EMT/paramedics’ personal

  2. Parent Pain and Catastrophizing Are Associated With Pain, Somatic Symptoms, and Pain-Related Disability Among Early Adolescents

    OpenAIRE

    Wilson, Anna C; Moss, Ashley; Palermo, Tonya M.; Fales, Jessica L.

    2013-01-01

    Objective To examine associations between parental history of pain and catastrophizing and their adolescent’s pain, somatic symptoms, catastrophizing, and disability. Methods Participants included 178 youths aged 11–14 years recruited through public schools. Adolescents completed measures assessing pain characteristics, somatic symptoms, and pain catastrophizing. Parents reported on their own pain, and catastrophizing about their adolescent’s pain. Results About one quarter of the adolescents...

  3. Robust catastrophe-free space agriculture on Mars

    Science.gov (United States)

    Yamashita, Masamichi

    During the early stage of CELSS research, economy was a selling point of the bio-regenerative life support concept. Until system integration was exercised in detail at mission planing for the International Space Station, the turning point from open system to CELSS was estimated 10 years of operation for 10 crew member as a consensus. Initial investment and operational cost for the 10-10 regenerative system was believed to be cheaper than the integrated amount of consumables for running open system. Any drop-out from recycling loop of materials is counted as “penalty”. Under this context, degree of closure was raised as an index to measure “maturity” of CELSS technology. Once it was found quite difficult to achieve 100 % closure perfect, science merit of CELSS study was redefined as a small scaled model of terrestrial biosphere. Natural ecosystem has huge sink and backyard in its materials loop. They provide a basis for keeping member in the ecology without falling into catastrophe. Low productivity at high biological diversity is a common key feature at the climax phase of ecosystem. Artificial ecosystem on ground relies on “unpaid” backyard function of surrounding biosphere together with strong control for realizing high productivity at less degree of bio-diversity. It should be noted that top criteria in engineering manned space system is robustness and survivability of crew. All other item is secondary, and just better to have. Without verification of catastrophe free, space agriculture will never be implemented for space and stay as a fantasy on ground forever. There is a great gap between ecology and this requirement for manned space system. In order to fill this gap, we should remind how gatherer and hunter was civilized after the agricultural revolution about ten thousand years ago. Planting cereal crop was a great second step in agricultural innovation. Cereal grain can be stored more than one year after its harvest. Food processing and

  4. The Properties of Fragments from Catastrophic Disruption Events

    Science.gov (United States)

    Giblin, I.; Martelli, G.; Farinella, P.; Paolicchi, P.; Di Martino, M.; Smith, P. N.

    1998-07-01

    We report and discuss the results from a series of catastrophic disruption experiments involving 21-cm spherical targets of alumina cement. These experiments were performed in the open air using a contact charge technique to simulate an impact at ∼6 km/s, typical of collision velocities between asteroids in the main belt. The 1992 experiments reported here, the most recent in an extensive experimental program initiated by Giuseppe Martelli before his death in 1994, follow directly from those described in I. Giblinet al.(1994a,Icarus110, 203-224), with a number of improvements to our instrumentation and analysis. By using two high-speed cameras at a mutual angle of 60° we have made possible a three-dimensional analysis of fragment velocities alongside the standard size, shape, ejection angle and rotation rate measurements which can easily be made from appropriately oriented single film records. In this paper we report on the results of the 1992 experiments, together with various unpublished data from 1989. We make a comparison between these sets of data and between our data and those of other researchers in this field. Also, we compare our results to those of the most recent semi-empirical model (SEM) of P. Paolicchiet al.(1996,Icarus121, 126-157) and to appropriate data concerning real asteroids, focusing on the dynamical families, which are believed to be remnants from the catastrophic disruption of precursor asteroids. A secondary purpose of this paper is to document our experiences and techniques in the implementation and analysis of these experiments. We find considerable variation in the slope of the fragment size distribution, even between closely similar experiments. Fragments are found to be slightly flatter and/or more elongated than those from some previous work, but in agreement with the previous study mentioned above. Fragment velocities are generally between 4 and 20 m/s with a few fast fragments observed up to 35 m/s. Only a weak correlation is

  5. Experimental reduction of pain catastrophizing modulates pain report but not spinal nociception as verified by mediation analyses.

    Science.gov (United States)

    Terry, Ellen L; Thompson, Kathryn A; Rhudy, Jamie L

    2015-08-01

    Pain catastrophizing is associated with enhanced pain; however, the mechanisms by which it modulates pain are poorly understood. Evidence suggests that catastrophizing modulates supraspinal processing of pain but does not modulate spinal nociception (as assessed by nociceptive flexion reflex [NFR]). Unfortunately, most NFR studies have been correlational. To address this, this study experimentally reduced catastrophizing to determine whether it modulates spinal nociception (NFR). Healthy pain-free participants (N = 113) were randomly assigned to a brief 30-minute catastrophizing reduction manipulation or a control group that received pain education. Before and after manipulations, 2 types of painful stimuli were delivered to elicit (1) NFR (single trains of stimuli) and (2) temporal summation of NFR (3 stimulations at 2 Hz). After each set of stimuli, participants were asked to report their pain intensity and unpleasantness, as well as their situation-specific catastrophizing. Manipulation checks verified that catastrophizing was effectively reduced. Furthermore, pain intensity and unpleasantness to both stimulation types were reduced by the catastrophizing manipulation, effects that were mediated by catastrophizing. Although NFRs were not affected by the catastrophizing manipulation, temporal summation of NFR was reduced. However, this effect was not mediated by catastrophizing. These results indicate that reductions in catastrophizing lead to reductions in pain perception but do not modulate spinal nociception and provides further evidence that catastrophizing modulates pain at the supraspinal, not the spinal, level.

  6. Observational Constraints on the Catastrophic Disruption Rate of Small Main Belt Asteroids

    CERN Document Server

    Denneau, Larry; Fitzsimmons, Alan; Hsieh, Henry; Kleyna, Jan; Granvik, Mikael; Micheli, Marco; Spahr, T; Vereš, Peter; Wainscoat, Richard; Burgett, W S; Chambers, K C; Draper, P W; Flewelling, H; Huber, M E; Kaiser, N; Morgan, J S; Tonry, J L

    2014-01-01

    We have calculated 90% confidence limits on the steady-state rate of catastrophic disruptions of main belt asteroids in terms of the absolute magnitude at which one catastrophic disruption occurs per year (HCL) as a function of the post-disruption increase in brightness (delta m) and subsequent brightness decay rate (tau). The confidence limits were calculated using the brightest unknown main belt asteroid (V = 18.5) detected with the Pan-STARRS1 (Pan-STARRS1) telescope. We measured the Pan-STARRS1's catastrophic disruption detection efficiency over a 453-day interval using the Pan-STARRS moving object processing system (MOPS) and a simple model for the catastrophic disruption event's photometric behavior in a small aperture centered on the catastrophic disruption event. Our simplistic catastrophic disruption model suggests that delta m = 20 mag and 0.01 mag d-1 99% of main belt catastrophic disruptions in the size range to which this study was sensitive (100 m) are not impact-generated, but are instead due ...

  7. Upset Prevention and Recovery for Unimpaired and Impaired Aircraft Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the project is the development of an on-board envelope estimation, protection and upset recovery tool to address loss of control incidents in...

  8. [2016 review on catastrophic antiphospholipid syndrome].

    Science.gov (United States)

    Costedoat-Chalumeau, Nathalie; Coutte, Laetitia; Le Guern, Véronique; Morel, Nathalie; Leroux, Gaelle; Paule, Romain; Mouthon, Luc; Piette, Jean-Charles

    2016-12-01

    The catastrophic antiphospholipid syndrome (CAPS) develops in at least 1% of patients with antiphospholipid syndrome, either primary or associated with systemic lupus erythematosus. CAPS reveals the antiphospholipid syndrome in about 50% of cases. The CAPS is characterized by rapidly-progressive widespread thromboses mainly affecting the microvasculature in the presence of antiphospholipid antibodies. In a few days, the patients develop multiorgan failure with renal insufficiency with severe hypertension, pulmonary, cerebral, cardiac, digestive and/or cutaneous involvement. The vital prognosis is frequently engaged. CAPS is often precipitated by infectious diseases, surgical procedures and/or withdrawal or modification of the anticoagulation. CAPS overall mortality rate has decreased and is currently below 30%. The main differential diagnoses are other thrombotic microangiopathies, and heparin-induced thrombocytopenia. The treatment of CAPS consists of the association of anticoagulation and steroids, plus plasma exchange and/or intravenous immunoglobulins. Cyclophosphamide is added only in patients with active systemic lupus erythematosus. The potential contribution of some additional therapies (rituximab, eculizumab or sirolimus) needs to be assessed. The prevention of CAPS is essential and is based upon the adequate management of the perioperative period when surgery cannot be avoided, the prompt treatment and the prevention with immunization of infections and the education of patients with antiphospholipid syndrome, especially for the management of oral anticoagulants.

  9. Quantifying the hurricane catastrophe risk to offshore wind power.

    Science.gov (United States)

    Rose, Stephen; Jaramillo, Paulina; Small, Mitchell J; Apt, Jay

    2013-12-01

    The U.S. Department of Energy has estimated that over 50 GW of offshore wind power will be required for the United States to generate 20% of its electricity from wind. Developers are actively planning offshore wind farms along the U.S. Atlantic and Gulf coasts and several leases have been signed for offshore sites. These planned projects are in areas that are sometimes struck by hurricanes. We present a method to estimate the catastrophe risk to offshore wind power using simulated hurricanes. Using this method, we estimate the fraction of offshore wind power simultaneously offline and the cumulative damage in a region. In Texas, the most vulnerable region we studied, 10% of offshore wind power could be offline simultaneously because of hurricane damage with a 100-year return period and 6% could be destroyed in any 10-year period. We also estimate the risks to single wind farms in four representative locations; we find the risks are significant but lower than those estimated in previously published results. Much of the hurricane risk to offshore wind turbines can be mitigated by designing turbines for higher maximum wind speeds, ensuring that turbine nacelles can turn quickly to track the wind direction even when grid power is lost, and building in areas with lower risk.

  10. Role of senescence and mitotic catastrophe in cancer therapy

    Directory of Open Access Journals (Sweden)

    Shukla Yogeshwer

    2010-01-01

    Full Text Available Abstract Senescence and mitotic catastrophe (MC are two distinct crucial non-apoptotic mechanisms, often triggered in cancer cells and tissues in response to anti-cancer drugs. Chemotherapeuticals and myriad other factors induce cell eradication via these routes. While senescence drives the cells to a state of quiescence, MC drives the cells towards death during the course of mitosis. The senescent phenotype distinguishes tumor cells that survived drug exposure but lost the ability to form colonies from those that recover and proliferate after treatment. Although senescent cells do not proliferate, they are metabolically active and may secrete proteins with potential tumor-promoting activities. The other anti-proliferative response of tumor cells is MC that is a form of cell death that results from abnormal mitosis and leads to the formation of interphase cells with multiple micronuclei. Different classes of cytotoxic agents induce MC, but the pathways of abnormal mitosis differ depending on the nature of the inducer and the status of cell-cycle checkpoints. In this review, we compare the two pathways and mention that they are activated to curb the growth of tumors. Altogether, we have highlighted the possibilities of the use of senescence targeting drugs, mitotic kinases and anti-mitotic agents in fabricating novel strategies in cancer control.

  11. On growth rate hysteresis and catastrophic crystal growth

    Science.gov (United States)

    Ferreira, Cecília; Rocha, Fernando A.; Damas, Ana M.; Martins, Pedro M.

    2013-04-01

    Different crystal growth rates as supersaturation is increasing or decreasing in impure media is a phenomenon called growth rate hysteresis (GRH) that has been observed in varied systems and applications, such as protein crystallization or during biomineralization. We have recently shown that the transient adsorption of impurities onto newly formed active sites for growth (or kinks) is sensitive to the direction and rate of supersaturation variation, thus providing a possible explanation for GRH [6]. In the present contribution, we expand on this concept by deriving the analytical expressions for transient crystal growth based on the energetics of growth hillock formation and kink occupation by impurities. Two types of GRH results are described according to the variation of kink density with supersaturation: for nearly constant density, decreasing or increasing supersaturation induce, respectively, growth promoting or inhibiting effects relative to equilibrium conditions. This is the type of GRH measured by us during the crystallization of egg-white lysozyme. For variable kink density, slight changes in the supersaturation level may induce abrupt variations in the crystal growth rate. Different literature examples of this so-called 'catastrophic' crystal growth are discussed in terms of their fundamental consequences.

  12. Investigating the outcomes of SPH models of catastrophic destruction

    Science.gov (United States)

    Dell'Oro, A.; Cellino, A.; Paolicchi, P.; Tanga, P.

    Smooth particle hydro-dynamics (SPH) codes have proved able to simulate satisfactorily the shattering processes in high-energy collisions among asteroids, reproducing the major observational evidences. In particular, SPH models reproduce fairly well the size distributions of the members of some asteroid families. A considerable difference between SPH models and Semi-Empirical Models (SEM) is that in the former the asteroids are ground up into very small fragments, the size of which is limited by the resolution of the code. Moreover, the subsequent ballistic dynamical evolution, driven by their mutual gravitational attraction, would result in a significant re-accumulation into many bodies. On the contrary, ejection velocity fields predicted by SEM allow the reaccumulation into very few bodies, sometimes only the largest remnant. This difference is a critical issue for the interpretation of the observational data in order to understand the physics of the catastrophic destruction process, and the physical characteristics of the asteroids themselves. We present a new analysis of some SPH velocity fields aiming to shed light on the intrinsic differences between SPH models and SEMs.

  13. Catastrophic debris avalanche deposit of Socompa volcano, northern Chile

    Science.gov (United States)

    Francis, P. W.; Gardeweg, M.; Ramirez, C. F.; Rothery, D. A.

    1985-01-01

    Between 10,000 and 500 yr ago the Socompa volcano in northern Chile experienced a catastrophic collapse of a 70 deg sector of the original cone, causing a debris avalanche that descended nearly 3000 m vertically and traveled more than 35 km from the volcano. The deposits cover some 490 sq km and have a minimum volume of 15 cu km. Parts of the original cone slumped in a nearly coherent form and are now preserved as large blocks more than 400 m high. The primary avalanche traveled northwestward over sloping ground before coming to rest transiently, forming a prominent marginal ridge, and then slid away northeastward to form a secondary flow, overriding much of the primary avalanche deposit. Abundant, prismatic, jointed dacite blocks within the debris avalanche deposit and a thin, fine-grained pumiceous deposit beneath it suggest that the collapse was triggered by magmatic activity and may have been accompanied by a violent lateral blast. Collapse was followed by eruption of pumiceous pyroclastic flows and extrusion of voluminous dacite domes.

  14. Quantum resonance catastrophe for conductance through a periodically driven barrier

    Science.gov (United States)

    Thuberg, Daniel; Reyes, Sebastián A.; Eggert, Sebastian

    2016-05-01

    We consider the quantum conductance in a tight-binding chain with a locally applied potential which is oscillating in time. The steady state for such a driven impurity can be calculated exactly for any energy and applied potential using the Floquet formalism. The resulting transmission has a nontrivial, nonmonotonic behavior depending on incoming momentum, driving frequency, and the strength of the applied periodic potential. Hence there is an abundance of tuning possibilities, which allows finding the resonances of total reflection for any choice of incoming momentum and periodic potential. Remarkably, this implies that even for an arbitrarily small infinitesimal impurity potential it is always possible to find a resonance frequency at which there is a catastrophic breakdown of the transmission T =0 . The points of zero transmission are closely related to the phenomenon of Fano resonances at dynamically created bound states in the continuum. The results are relevant for a variety of one-dimensional systems where local AC driving is possible, such as quantum nanodot arrays, ultracold gases in optical lattices, photonic crystals, or molecular electronics.

  15. Chromothripsis: how does such a catastrophic event impact human reproduction?

    Science.gov (United States)

    Pellestor, Franck

    2014-03-01

    The recent discovery of a new kind of massive chromosomal rearrangement, baptized chromothripsis (chromo for chromosomes, thripsis for shattering into pieces), greatly modifies our understanding of molecular mechanisms implicated in the repair of DNA damage and the genesis of complex chromosomal rearrangements. Initially described in cancers, and then in constitutional rearrangements, chromothripsis is characterized by the shattering of one (or a few) chromosome(s) segments followed by a chaotic reassembly of the chromosomal fragments, occurring during one unique cellular event. The diversity and the high complexity of chromothripsis events raise questions about their origin, their ties to chromosome instability and their impact in pathology. Several causative mechanisms, involving abortive apoptosis, telomere erosion, mitotic errors, micronuclei formation and p53 inactivation, have been proposed. The remarkable point is that all these mechanisms have been identified in the field of human reproduction as causal factors for reproductive failures and chromosomal abnormalities. Consequently, it seems important to consider this unexpected catastrophic phenomenon in the context of fertilization and early embryonic development in order to discuss its potential impact on human reproduction.

  16. Fold catastrophe model of dynamic pillar failure in asymmetric mining

    Institute of Scientific and Technical Information of China (English)

    PAN Yue; LI Ai-wu; QI Yun-song

    2009-01-01

    A rock burst disaster not only destroys the pit facilities and results in economic loss but it also threatens the life of the miners. Pillar rock burst has a higher frequency of occurrence in the pit compared to other kinds of rock burst. Understanding the cause, magnitude and prevention of pillar rock burst is a significant undertaking. Equations describing the bending moment and displacement of the rock beam in asymmetric mining have been deduced for simplified asymmetric beam-pillar systems. Using the symbolic operation software MAPLE 9.5 a catastrophe model of the dynamic failure of an asymmetric rock-beam pillar system has been established. The differential form of the total potential function deduced from the law of conservation of energy was used for this deduction. The critical conditions and the initial and final positions of the pillar during failure have been given in analytical form. The amount of elastic energy released by the rock beam at the instant of failure is determined as well as. A diagrammatic form showing the pillar failure was plotted using MATLAB software. This plot contains a wealth of information and is important for understanding the behavior during each deformation phase of the rock-beam pillar system. The graphic also aids in distinguishing the equivalent stiffness of the rock beam in different directions.

  17. A case of catastrophic antiphospholipid syndrome: first report with advanced cardiac imaging using MRI.

    Science.gov (United States)

    Rosenbaum, A N; Anavekar, N S; Ernste, F C; Mankad, S V; Le, R J; Manocha, K K; Barsness, G W

    2015-10-01

    This present case pertains to a 48-year-old woman with a history of antiphospholipid syndrome, who presented with progressive fatigue, generalized weakness, and orthopnea acutely. She had a prior diagnosis of antiphospholipid syndrome with recurrent deep vein thromboses (DVTs) and repeated demonstration of lupus anticoagulants. She presented in cardiogenic shock with markedly elevated troponin and global myocardial dysfunction on echocardiography, and cardiac catheterization revealed minimal disease. Cardiac magnetic resonance imaging was performed, which revealed findings of perfusion defects and microvascular obstruction, consistent with the pathophysiology of catastrophic antiphospholipid syndrome (CAPS). Diagnosis was made based on supportive imaging, including head magnetic resonance imaging (MRI) revealing multifocal, acute strokes; microvascular thrombosis in the dermis; and subacute renal infarctions. The patient was anticoagulated with intravenous unfractionated heparin and received high-dose methylprednisolone, plasmapheresis, intravenous immunoglobulin, and one dose each of rituximab and cyclophosphamide. She convalesced with eventual myocardial recovery after a complicated course. The diagnosis of CAPS relies on the presence of (1) antiphospholipid antibodies and (2) involvement of multiple organs in a microangiopathic thrombotic process with a close temporal association. The myocardium is frequently affected, and heart failure, either as the presenting symptom or cause of death, is common. Despite echocardiographic evidence of myocardial dysfunction in such patients, MRIs of CAPS have not previously been reported. This case highlights the utility in assessing the involvement of the myocardium by the microangiopathic process with MRI. Because the diagnosis of CAPS requires involvement in multiple organ systems, cardiac MRI is likely an underused tool that not only reaffirms the pathophysiology of CAPS, but could also clue clinicians in to the

  18. Radiation incidents in dentistry

    Energy Technology Data Exchange (ETDEWEB)

    Lovelock, D.J. [Dental Hospital and School, Newcastle upon Tyne (United Kingdom). Dept. of Radiology

    1996-12-31

    Most dental practitioners act as their own radiographer and radiologist, unlike their medical colleagues. Virtually all dental surgeons have a dental X-ray machine for intraoral radiography available to them and 40% of dental practices have equipment for dental panoramic tomography. Because of the low energy of X-ray equipment used in dentistry, radiation incidents tend to be less serious than those associated with other aspects of patient care. Details of 47 known incidents are given. The advent of the 1985 and 1988 Ionising Radiation Regulations has made dental surgeons more aware of the hazards of radiation. These regulations, and general health and safety legislation, have led to a few dental surgeons facing legal action. Because of the publicity associated with these court cases, it is expected that there will be a decrease in radiation incidents arising from the practice of dentistry. (author).

  19. Catastrophe models and the expansion method: A review of issues and an application to the econometric modeling of economic growth

    Directory of Open Access Journals (Sweden)

    Emilio Casetti

    1997-01-01

    Full Text Available Many negative reactions to Catastrophe Theory have been triggered by overly simplistic applications unintended and unsuited for statistical-econometric estimation, inference, and testing. In this paper it is argued that stochastic catastrophe models constructed using the Expansion Method hold the most promise to widen the acceptance of Catastrophe Theory by analytically oriented scholars in the social sciences and elsewhere. The paper presents a typology of catastrophe models, and demonstrates the construction and estimation of an econometric expanded cusp catastrophe model of economic growth.

  20. Nuclear catastrophe in Japan. Health consequences resulting from Fukushima; Atomkatastrophe in Japan. Gesundheitliche Folgen von Fukushima

    Energy Technology Data Exchange (ETDEWEB)

    Paulitz, Henrik; Eisenberg, Winfrid; Thiel, Reinhold

    2013-03-06

    On 11 March 2011, a nuclear catastrophe occurred at the Fukushima Dai-ichi nuclear power plant in Japan in the wake of an earthquake and due to serious safety deficiencies. This resulted in a massive and prolonged release of radioactive fission and decay products. Approximately 20% of the radioactive substances released into the atmosphere have led to the contamination of the landmass of Japan with 17,000 becquerels per square meter of cesium-137 and a comparable quantity of cesium-134. The initial health consequences of the nuclear catastrophe are already now, after only two years, scientifically verifiable. Similar to the case of Chernobyl, a decline in the birth rate was documented nine months after the nuclear catastrophe. Throughout Japan, the total drop in number of births in December 2011 was 4362, with the Fukushima Prefecture registering a decline of 209 births. Japan also experienced a rise in infant mortality, with 75 more children dying in their first year of life than expected statistically. In the Fukushima Prefecture alone, some 55,592 children were diagnosed with thyroid gland nodules or cysts. In contrast to cysts and nodules found in adults, these findings in children must be classified as precancerous. There were also the first documented cases in Fukushima of thyroid cancer in children. The present document undertakes three assessments of the expected incidence of cancer resulting from external exposure to radiation. These are based on publications in scientific journals on soil contamination in 47 prefectures in Japan, the average total soil contamination, and, in the third case, on local dose rate measurements in the fall of 2012. Taking into consideration the shielding effect of buildings, the medical organization IPPNW has calculated the collective lifetime doses for individuals at 94,749 manSv, 206,516 manSv, and 118,171 manSv, respectively. In accordance with the risk factors set by the European Committee on Radiation Risk (ECRR) for death

  1. Lightning incidents in Mongolia

    Directory of Open Access Journals (Sweden)

    Myagmar Doljinsuren

    2015-11-01

    Full Text Available This is one of the first studies that has been conducted in Mongolia on the distribution of lightning incidents. The study covers a 10-year period from 2004 to 2013. The country records a human death rate of 15.4 deaths per 10 million people per year, which is much higher than that of many countries with similar isokeraunic level. The reason may be the low-grown vegetation observed in most rural areas of Mongolia, a surface topography, typical to steppe climate. We suggest modifications to Gomes–Kadir equation for such countries, as it predicts a much lower annual death rate for Mongolia. The lightning incidents spread over the period from May to August with the peak of the number of incidents occurring in July. The worst lightning affected region in the country is the central part. Compared with impacts of other convective disasters such as squalls, thunderstorms and hail, lightning stands as the second highest in the number of incidents, human deaths and animal deaths. Economic losses due to lightning is only about 1% of the total losses due to the four extreme weather phenomena. However, unless precautionary measures are not promoted among the public, this figure of losses may significantly increase with time as the country is undergoing rapid industrialization at present.

  2. Catastrophe model for the exposure to blood-borne pathogens and other accidents in health care settings.

    Science.gov (United States)

    Guastello, S J; Gershon, R R; Murphy, L R

    1999-11-01

    Catastrophe models, which describe and predict discontinuous changes in system state variables, were used to model the exposure to blood and bodily fluids and more conventional occupational accidents among 1708 health care workers. Workers at three hospitals completed a survey measuring HIV-relevant exposures (needlesticks, cuts, splashes, contact with open wounds), the accident rate for broadly-defined injuries, and several occupationally relevant themes: safety climate, shift work, depression symptoms, work pace, verbal abuse, and professional group membership. A cusp (cubic polynomial) model predicting HIV-relevant exposures specifically was more accurate (R2 = 0.56) than a comparable linear model containing the same variables (R2 = 0.07). Some of the foregoing variables predisposed workers to greater differences in HIV-relevant and general accident exposures: shiftwork, climate, depressive symptoms, and work pace. Other variables governed how close an individual was to a critical threshold where a harmful incident would take place: verbal abuse, professional group membership. Similarly, a cusp model for accident incidents predicted from HIV-relevant exposures and occupational variables was also more accurate (R2 = 0.75) than comparison models. Two variables predisposed the worker to a greater accident risk: depression symptoms and shift work. Four other variables predisposed the worker to lesser accident risk: job satisfaction, safety climate, environmental stressors, and work pace. Compliance with the universal precautions and HIV-related training were not relevant to either of the models.

  3. Dyadic analysis of child and parent trait and state pain catastrophizing in the process of children's pain communication.

    Science.gov (United States)

    Birnie, Kathryn A; Chambers, Christine T; Chorney, Jill; Fernandez, Conrad V; McGrath, Patrick J

    2016-04-01

    When explored separately, child and parent catastrophic thoughts about child pain show robust negative relations with child pain. The objective of this study was to conduct a dyadic analysis to elucidate intrapersonal and interpersonal influences of child and parent pain catastrophizing on aspects of pain communication, including observed behaviours and perceptions of child pain. A community sample of 171 dyads including children aged 8 to 12 years (89 girls) and parents (135 mothers) rated pain catastrophizing (trait and state versions) and child pain intensity and unpleasantness following a cold pressor task. Child pain tolerance was also assessed. Parent-child interactions during the cold pressor task were coded for parent attending, nonattending, and other talk, and child symptom complaints and other talk. Data were analyzed using the actor-partner interdependence model and hierarchical multiple regressions. Children reporting higher state pain catastrophizing had greater symptom complaints regardless of level of parent state pain catastrophizing. Children reporting low state pain catastrophizing had similar high levels of symptom complaints, but only when parents reported high state pain catastrophizing. Higher child and parent state and/or trait pain catastrophizing predicted their own ratings of higher child pain intensity and unpleasantness, with child state pain catastrophizing additionally predicting parent ratings. Higher pain tolerance was predicted by older child age and lower child state pain catastrophizing. These newly identified interpersonal effects highlight the relevance of the social context to children's pain expressions and parent perceptions of child pain. Both child and parent pain catastrophizing warrant consideration when managing child pain.

  4. Psychometric properties of the Brazilian version of the Pain Catastrophizing Scale for acute low back pain

    Directory of Open Access Journals (Sweden)

    Renata Antunes Lopes

    2015-05-01

    Full Text Available Measurement instruments of pain catastrophizing for middle-aged and elderly individuals are needed to understand its impact on low back pain. The goals were to cross-culturally adapt the Pain Catastrophizing Scale, assess the construct validity through Rasch analysis, and verify reliability and convergent validity of pain catastrophizing with psychosocial factors. 131 individuals aged 55 years and older with acute low back pain were interviewed . The intra-rater reliability was Kp = 0.80 and interrater Kp = 0.75. The Rasch analysis found adequate reliability coefficients (0.95 for items and 0.90 for individuals . The separation index for the elderly was 2.95 and 4.59 items. Of the 13 items, one did not fit the model, which was justified in the sample evaluated. The pain catastrophizing correlated with most psychosocial factors. The instrument proved to be clinically useful. Subsequent studies should carry out the same analysis in different populations.

  5. Establishment and Application of Assessment Indicator System of Agricultural Catastrophe Vulnerability

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    To give play to the role of agricultural catastrophe risk fund in spreading agricultural catastrophe risk,we select natural conditions,economic conditions,social conditions,as the external vulnerability assessment indicators;select commodity rate of agricultural products,substitutability of agricultural products,the extent of agricultural products being related to the national economy and the people’s livelihood,as the internal vulnerability assessment indicators.We assign weight to indicators using Analytic Hierarchy Process,and establish assessment indicator system of agricultural catastrophe vulnerability,to analyze the compensation for losses of different agricultural products arising from agricultural catastrophe in different regions.And we take the case of rice in Sichuan Province,to demonstrate the role this indicator system.

  6. Study on Catastrophic Air Current Early-warning and Control System of Coalmines

    Directory of Open Access Journals (Sweden)

    L.F. Fang

    2016-02-01

    Full Text Available Catastrophic air current significantly influences the stability of ventilation system, and existing studies have not considered the flow characteristics of catastrophic air current when designing the control systems. To analyze the effects of different kinds of coalmine accidents on safety production, grey relation entropy theory was used to analyze the hazard assessment of coalmine accidents. Fluent software was employed to study the flow characteristics of catastrophic air current, and the catastrophic air current early-warning and control system of coalmine was researched according to the theoretical analysis and numerical simulation. The threat of fire accidents and roof accidents were larger than other accidents. The influence of temperature and CO volume fraction distribution of fire accidents to the tailwind side was larger than that of the weather side, and gradient decreased on the weather side. This system can effectively control the spread of fire and poisonous gas,

  7. The role of positive traits and pain catastrophizing in pain perception.

    Science.gov (United States)

    Pulvers, Kim; Hood, Anna

    2013-05-01

    A variety of biological, psychological, and social factors interact to influence pain. This article focuses on two distinct, but connected, psychological factors--positive personality traits and pain catastrophizing--and their link with pain perception in healthy and clinical populations. First, we review the protective link between positive personality traits, such as optimism, hope, and self-efficacy, and pain perception. Second, we provide evidence of the well-established relationship between pain catastrophizing and pain perception and other related outcomes. Third, we outline the inverse relationship between positive traits and pain catastrophizing, and offer a model that explains the inverse link between positive traits and pain perception through lower pain catastrophizing. Finally, we discuss clinical practice recommendations based on the aforementioned relationships.

  8. Global Catastrophes in Perspective: Asteroid Impacts vs Climate Change

    Science.gov (United States)

    Boslough, M. B.; Harris, A. W.

    2008-12-01

    When allocating resources to address threats, decision makers are best served by having objective assessments of the relative magnitude of the threats in question. Asteroids greater than about 1 km in diameter are assumed by the planetary impact community to exceed a "global catastrophe threshold". Impacts from smaller objects are expected to cause local or regional destruction, and would be the proximate cause of most associated fatalities. Impacts above the threshold would be expected to alter the climate, killing billions of people and causing a collapse of civilization. In this apocalyptic scenario, only a small fraction of the casualties would be attributable to direct effects of the impact: the blast wave, thermal radiation, debris, ground motion, or tsunami. The vast majority of deaths would come later and be due to indirect causes: starvation, disease, or violence as a consequence of societal disruption related to the impact-induced global climate change. The concept of a catastrophe threshold comes from "nuclear winter" studies, which form the basis for quantitative estimates of the consequences of a large impact. The probability estimates come from astronomical observations and statistical analysis. Much of the impact threat, at its core, is a climate-change threat. Prior to the Spaceguard Survey of Near-Earth Objects (NEOs), the chance of dying from an asteroid impact was estimated to be 1 in 25,000 (Chapman & Morrison, 1994). Most of the large asteroids have now been discovered, and none is on an impact trajectory. Moreover, new data show that mid-sized asteroids (tens to hundreds of meters across) are less abundant than previously thought, by a factor of three. We now estimate that the lifetime odds of being killed by the impact of one of the remaining undiscovered NEOs are about one in 720,000 for individuals with a life expectancy of 80 years (Harris, 2008). One objective way to compare the relative magnitude of the impact threat to that of

  9. Pediatric catastrophic antiphospholipid syndrome: descriptive analysis of 45 patients from the "CAPS Registry".

    Science.gov (United States)

    Berman, Horacio; Rodríguez-Pintó, Ignasi; Cervera, Ricard; Gregory, Simone; de Meis, Ernesto; Rodrigues, Carlos Ewerton Maia; Aikawa, Nádia Emi; de Carvalho, Jozélio Freire; Springer, Janusz; Niedzwiecki, Maciej; Espinosa, Gerard

    2014-02-01

    Given the lack of information about catastrophic antiphospholipid syndrome (APS) in pediatric patients, the objective of the current study was to describe the clinical characteristics, laboratory features, treatment, and outcome of pediatric patients with catastrophic APS and compare them with the adult patients with catastrophic APS. We identified patients who were under 18years of age at time of catastrophic APS diagnosis included in the international registry of patients with catastrophic APS (CAPS Registry). Their main demographic and clinical characteristics, laboratory features, treatment, and outcome were described and compared with those of adult patients with catastrophic APS. From the 446 patients included in the CAPS Registry as of May 2013, 45 (10.3%) patients developed 46 catastrophic events before 18years of age (one patient presented two episodes). Overall, 32 (71.1%) patients were female and the mean age was 11.5±4.6years (range, 3months-18years). A total of 31 (68.9%) patients suffered from primary APS and 13 (28.9%) from systemic lupus erythematosus (SLE). The main differences between the two groups of patients were the higher prevalence of infections as precipitating factor for catastrophic event in the pediatric population (60.9% versus 26.8% in the adult population, p<0.001) and of peripheral vessel thrombosis (52.2% versus 34.3%, p=0.017). In addition, catastrophic APS was the first manifestation of APS more frequently in pediatric patients (86.6% versus 45.2%, p<0.001). Interestingly, pediatric patients showed a trend of lower mortality, although the difference was not statistically significant (26.1% versus 40.2%; odds ratio, 1.9; 95% confidence interval, 0.96-3.79; p=0.063). No differences were found neither in the laboratory features nor in the isolated or combination treatments between groups. Catastrophic APS in pediatric patients is a rare disease. There are minimal differences in the clinical and laboratory features, treatment, and

  10. Fully-coupled hydrometeorological prediction of catastrophic Mediterranean floods

    Science.gov (United States)

    Rebora, N.; Gabellani, S.; Rudari, R.; Silvestro, F.; Parodi, A.; Gochis, D.

    2012-12-01

    On November 4th, 2011, the city of Genoa, Italy, located between the Tyrrhenian Sea and the Apennine mountains, was witness to a catastrophic flash flood. About 500 millimeters of rain -a third of the average annual rainfall- fell in approximately six hours. The waters that flooded the town center equated to an approximately 300 year flood event. Six people perished, commercial property was inundated, cars were swept away and many trees were uprooted. We analyze the performance of cloud-permitting (1 km) model simulations of the convective system responsible for this extreme event using the Advanced Research Weather and Forecasting Model (ARW-WRF, version 3.3) with its associated hydrological modeling extension ('WRF-Hydro') focusing on the utility of model quantitative precipitation forecasts (QPFs) for flash flood prediction. WRF model skill is assessed with respect to specification of cloud microphysics, convection and land surface physics parameterizations. The QPF results strongly suggest an event dominated by comparatively shallow warm rain processes where local maxima were the product of both synoptic scale dynamics and orographic enhancement over the Apennine mountain range. Land and sea surface temperature forcing was assess but found to be secondary in importance. Streamflow prediction skill from the fully coupled WRF-Hydro modeling system was compared against observations and against offline or 'uncoupled' hydrological model runs, driven by several quantitative precipitation estimate (QPEs) products. The results illustrate the significant sensitivity of the predicted (simulated) streamflow event to QPF (QPE) skill and emphasize the importance of taking into account many factors and sources of error in the hydrometeorological prediction chain. The end product of this study is a comprehensive evaluation and justification for optimal configurations of the WRF-Hydro modeling system for high-impact Mediterranean flood events for use in future forecasting

  11. A CATASTROPHIC-CUM-RESTORATIVE QUEUING SYSTEM WITH CORRELATED BATCH ARRIVALS AND VARIABLE CAPACITY

    Directory of Open Access Journals (Sweden)

    Rakesh Kumar

    2008-07-01

    Full Text Available In this paper, we study a catastrophic-cum-restorative queuing system with correlated batch arrivals and service in batches of variable sizes. We perform the transient analysis of the queuing model. We obtain the Laplace Transform of the probability generating function of system size. Finally, some particular cases of the model have been derived and discussed. Keywords: Queue length, Catastrophes, Correlated batch arrivals, Broadband services, Variable service capacity, and Restoration.

  12. Floating worlds and their phantoms in the aftermath of social catastrophes.

    Science.gov (United States)

    Kimbles, Samuel

    2017-02-01

    In this paper the author describes certain kinds of images (phantoms) that appear in the aftermath of social catastrophes. These phantoms come with an underlying narrative structure, which the author describes as phantom narratives. Phantom narratives show how the unconscious, working at the group and individual levels, provides political and social contexts within which the individual may find a different kind of containment for these catastrophes. In this way their suffering may be potentially processed psychologically and related to symbolically.

  13. Earthquake recovery of historic buildings: exploring cost and time needs.

    Science.gov (United States)

    Al-Nammari, Fatima M; Lindell, Michael K

    2009-07-01

    Disaster recovery of historic buildings has rarely been investigated even though the available literature indicates that they face special challenges. This study examines buildings' recovery time and cost to determine whether their functions (that is, their use) and their status (historic or non-historic) affect these outcomes. The study uses data from the city of San Francisco after the 1989 Loma Prieta earthquake to examine the recovery of historic buildings owned by public agencies and non-governmental organisations. The results show that recovery cost is affected by damage level, construction type and historic status, whereas recovery time is affected by the same variables and also by building function. The study points to the importance of pre-incident recovery planning, especially for building functions that have shown delayed recovery. Also, the study calls attention to the importance of further investigations into the challenges facing historic building recovery.

  14. Metacognitive beliefs moderate the relationship between catastrophic misinterpretation and health anxiety.

    Science.gov (United States)

    Bailey, Robin; Wells, Adrian

    2015-08-01

    Catastrophic misinterpretations of bodily symptoms have a central role in cognitive-behavioural models of health anxiety. However, the metacognitive (S-REF) model postulates that psychological disturbance is linked more to beliefs about thinking i.e., metacognition. Equally the relationship between catastrophic misinterpretation and health anxiety should be moderated by metacognition, in particular negative beliefs about the uncontrollability and danger of thinking (MCQNeg). Participants (N = 351) completed measures to examine the relationship between these variables. Results indicated positive relationships between metacognition, catastrophic misinterpretation, and health anxiety. Moderation analysis showed that the effect of catastrophic misinterpretations on health anxiety was explained by the proposed interaction with metacognition. Follow-up regression analysis demonstrated the interaction term explained variance in health anxiety when controlling for other variables, and was a stronger unique predictor of health anxiety than catastrophic misinterpretation. Metacognition appears to be an important factor in the relationship between catastrophic misinterpretation and health anxiety, and would have important implications for existing models and treatment.

  15. Catastrophic Health Expenditure and Household Impoverishment: a case of NCDs prevalence in Kenya

    Directory of Open Access Journals (Sweden)

    Daniel Mwai

    2016-03-01

    Full Text Available Introduction and problem: Non-Communicable Diseases (NCDs have become one of the leading causes of morbidity and mortality in Kenya. Their claim on financial and time resources adversely affects household welfare. Health care cost for NCDs in Kenya is predominantly paid by households as OOP. Health expenditure on NCD stands at 6.2% of Total Health Expenditure which is 0.4 % of the total gross domestic product of the country. This expenditure scenario could have implications on household welfare through catastrophic expenditure in Kenya. Most studies done on catastrophic expenditure in Kenya have not looked at the effect of NCD on poverty. Methodology: The paper has investigated the determinants of catastrophic health spending in a household with special focus on the NCDs. It has also investigated the effect of catastrophic expenditure on household welfare.A National household level survey data on expenditure and utilization is used. Controlling for endogeneity, the results revealed that NCDs and communicable diseases contribute significantly to the likelihood of a household incurring catastrophic expenditure. Results: Although all types of sicknesses have negative effects on household welfare, NCDs have more severe impacts on impoverishment. Policy wise, government and development partners should put in place a health financing plan entailing health insurance and resource pooling as a mean towards social protection. Key words:  Non-Communicable Diseases (NCD, Catastrophic Health Expenditure, endogeneity Impoverishment

  16. Relationships Between Refraining From Catastrophic Thinking, Repetitive Negative Thinking, and Psychological Distress.

    Science.gov (United States)

    Sugiura, Tomoko; Sugiura, Yoshinori

    2016-10-01

    Skills to refrain from catastrophic thinking were negatively related to worry and a wide range of psychological distress. Repetitive negative thinking (including worry) is proposed as a common etiological factor for a wide range of psychological distress. Therefore, reduced repetitive negative thinking would mediate the negative relation between refraining from catastrophic thinking and psychological distress (depression, social anxiety, phobia, generalized anxiety, and obsessions and compulsions). As an overlap between five indices of psychological distress was expected, we first computed latent factors underlying them, which were then predicted by refraining from catastrophic thinking and repetitive negative thinking. Cross-sectional questionnaire data from 125 nonclinical voluntarily participating students (M age = 19.0 years, SD = 3.6; 54% women) supported the predictions: refraining from catastrophic thinking was negatively correlated with depression, social anxiety, phobia, generalized anxiety, and obsession and compulsion. Repetitive negative thinking mediated the negative relationship between refraining from catastrophic thinking and latent factors underlying psychological distress (Fear and Distress). Refraining from catastrophic thinking may be negatively correlated with psychological distress due to its negative relation to repetitive negative thinking.

  17. Incident Wave Climate at the OWC Pico Plant

    DEFF Research Database (Denmark)

    Le Crom, I.; Cabrera Bermejo, H.; Pecher, Arthur

    2011-01-01

    The aim of the study is to retrieve the incident wave information that coincides with former Pico plant operation periods. The recent implementation of a directional pressure sensor for wave measurement as well as the recovery of the data gathered by a directional wave rider buoy allowed embarking...

  18. Does changing pain-related knowledge reduce pain and improve function through changes in catastrophizing?

    Science.gov (United States)

    Lee, Hopin; McAuley, James H; Hübscher, Markus; Kamper, Steven J; Traeger, Adrian C; Moseley, G Lorimer

    2016-04-01

    Evidence from randomized controlled studies shows that reconceptualizing pain improves patients' knowledge of pain biology, reduces catastrophizing thoughts, and improves pain and function. However, causal relationships between these variables remain untested. It is hypothesized that reductions in catastrophizing could mediate the relationship between improvements in pain knowledge and improvements in pain and function. To test this causal mechanism, we conducted longitudinal mediation analyses on a cohort of 799 patients who were exposed to a pain education intervention. Patients provided responses to the neurophysiology of pain questionnaire, catastrophic thoughts about pain scale, visual analogue pain scale, and the patient specific functional scale, at baseline, 1-month, 6-month, and 12-month follow-up. With adjustment for potential confounding variables, an improvement in pain biology knowledge was significantly associated with a reduction in pain intensity (total effect = -2.20, 95% confidence interval [CI] = -2.96 to -1.44). However, this effect was not mediated by a reduction in catastrophizing (indirect effect = -0.16, 95% CI = -0.36 to 0.02). This might be due to a weak, nonsignificant relationship between changes in catastrophizing and pain intensity (path b = 0.19, 95% CI = -0.03 to 0.41). Similar trends were found in models with function as the outcome. Our findings indicate that change in catastrophizing did not mediate the effect of pain knowledge acquisition on change in pain or function. The strength of this conclusion is moderated, however, if patient-clinician relational factors are conceptualized as a consequence of catastrophizing, rather than a cause.

  19. Walking Recovery after a Hip Fracture: A Prospective Follow-Up Study among Community-Dwelling over 60-Year Old Men and Women

    Directory of Open Access Journals (Sweden)

    Anu Salpakoski

    2014-01-01

    Full Text Available Purpose. Recovery of walking outdoors after hip fracture is important for equal participation in the community. The causes of poor recovery are not fully understood. This study investigates recovery of walking outdoors and associated determinants after hip fracture. Methods. A prospective follow-up study, among clinical sample of 81 community-dwelling hip fracture patients over 60 years. Perceived difficulty in walking outdoors and 500 meters was assessed before fracture, at discharge to home (3.2 ± 2.2 weeks after surgery, and on average 6.0 ± 3.3 weeks after discharge. Potential determinants for walking recovery were assessed. Linear latent trajectory model was used to analyse changes during follow-up. Association between walking trajectories and potential determinants was analysed with a logistic regression model. Results. Two trajectories, No-to-minor-difficulty and Catastrophic, were found. Thirty-eight percent of the participants ended up in the Catastrophic trajectory for walking outdoors and 67% for 500 meters. Multivariate logistic regression analysis revealed that use of walking aid and indoor falls before fracture and prolonged pain were independently associated with catastrophic decline in both primary outcomes: difficulty in walking outdoors and 500 meters. Conclusions. A large proportion of community-dwelling older people recovering from hip fracture experienced catastrophic decline in outdoor walking. Acknowledging recovery prognoses at early stage enables individualized rehabilitation.

  20. Immune recovery vitritis

    Directory of Open Access Journals (Sweden)

    Dujić Mirjana

    2007-01-01

    Full Text Available Introduction Immune recovery vitritis (IRV is symptomatic vitritis of > 1+ severity associated with inactive cytomegalovirus (CMV retinitis. It is an opportunistic infection of the eye, in the patients who suffer from AIDS, and is treated with a highly active antiretroviral therapy (HAART. As a result of this therapy, there is an immune reconstitution in the body and inflammation of the vitreous body. Objective The aim of the study was to show the incidence of IRV in patients treated with HAART. Method A retrospective study was conducted in patients who suffered from CMV retinitis. Twenty-one were treated with HAART and had the diagnosis of CMV retinitis, as well. All of them were examined by the same ophthalmologist who peformed slit lamp examination with mydriasis and indirect ophthalmoscopy. Results Nine of 21 patients developed IRV as a complication of HAART, two had cystoid macular edema (CMO. Conclusion CMV retinitis develops when the number of CD4+ T lymphocytes drops below 50/mm3. This results in necrotic retinitis which, if untreated, leads to complete loss of vision. With the introduction of HAART, we learned that the reconstitution of immune status was achieved as well as life expectancy, but there was a dramatic decline in the opportunistic infection, including CMV retinitis, as well. With the immune reconstitution, the inflammation develops in the eye, known as IRV. Sometimes, it is necessary to treat this condition, but in the case of our patients, the inflammation was mild, and no treatment was necessary.

  1. Medication incidents reported to an online incident reporting system.

    LENUS (Irish Health Repository)

    Alrwisan, Adel

    2011-01-15

    AIMS: Approximately 20% of deaths from adverse events are related to medication incidents, costing the NHS an additional £500 million annually. Less than 5% of adverse events are reported. This study aims to assess the reporting rate of medication incidents in NHS facilities in the north east of Scotland, and to describe the types and outcomes of reported incidents among different services. Furthermore, we wished to quantify the proportion of reported incidents according to the reporters\\' profession. METHODS: A retrospective description was made of medication incidents reported to an online reporting system (DATIX) over a 46-month-period (July 2005 to April 2009). Reports originated from acute and community hospitals, mental health, and primary care facilities. RESULTS: Over the study period there were 2,666 incidents reported with a mean monthly reporting rate of 78.2\\/month (SD±16.9). 6.1% of all incidents resulted in harm, with insulin being the most commonly implicated medication. Nearly three-quarters (74.2%, n=1,978) of total incidents originated from acute hospitals. Administration incidents were implicated in the majority of the reported medication incidents (59%), followed by prescribing (10.8%) and dispensing (9.9%), while the nondescript "other medication incidents" accounted for 20.3% of total incidents. The majority of reports were made by nursing and midwifery staff (80%), with medical and dental professionals reporting the lowest number of incidents (n=56, 2%). CONCLUSIONS: The majority of medication incidents in this study were reported by nursing and midwifery staff, and were due to administration incidents. There is a clear need to elucidate the reasons for the limited contribution of the medical and dental professionals to reporting medication incidents.

  2. Congestion with incidents

    DEFF Research Database (Denmark)

    Fosgerau, Mogens

    2010-01-01

    This paper considers the impact of random delays during a repeatedly occurring demand peak in a congested facility, such as an airport or an urban road. Congestion is described in the form of a dynamic queue using the Vickrey bottleneck model and assuming Nash equilibrium in departure times. Every...... period an incident may occur at a random time, temporarily reducing the bottleneck capacity to zero. The paper gives some properties of Nash equilibrium and the social optimum as well as a pretty good welfare improving tolling scheme....

  3. Determinants of mitotic catastrophe on abrogation of the G2 DNA damage checkpoint by UCN-01.

    Science.gov (United States)

    On, Kin Fan; Chen, Yue; Ma, Hoi Tang; Chow, Jeremy P H; Poon, Randy Y C

    2011-05-01

    Genotoxic stress such as ionizing radiation halts entry into mitosis by activation of the G(2) DNA damage checkpoint. The CHK1 inhibitor 7-hydroxystaurosporine (UCN-01) can bypass the checkpoint and induce unscheduled mitosis in irradiated cells. Precisely, how cells behave following checkpoint abrogation remains to be defined. In this study, we tracked the fates of individual cells after checkpoint abrogation, focusing in particular on whether they undergo mitotic catastrophe. Surprisingly, while a subset of UCN-01-treated cells were immediately eliminated during the first mitosis after checkpoint abrogation, about half remained viable and progressed into G(1). Both the delay of mitotic entry and the level of mitotic catastrophe were dependent on the dose of radiation. Although the level of mitotic catastrophe was specific for different cell lines, it could be promoted by extending the mitosis. In supporting this idea, weakening of the spindle-assembly checkpoint, by either depleting MAD2 or overexpressing the MAD2-binding protein p31(comet), suppressed mitotic catastrophe. Conversely, delaying of mitotic exit by depleting either p31(comet) or CDC20 tipped the balance toward mitotic catastrophe. These results underscore the interplay between the level of DNA damage and the effectiveness of the spindle-assembly checkpoint in determining whether checkpoint-abrogated cells are eliminated during mitosis.

  4. Abrupt Climate Change. Lessons from Integrated Catastrophic Risk Management. Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    Ermolieva, T.; Obersteiner, M.

    2003-05-06

    This paper is an extended version of the talks 'Uncertainty and Robust Solutions: Lessons from IIASA Case Studies on Catastrophic Risk Management and Economic Growth under Shocks' given on 12 June 2002 and 'Sink Technologies and Climate Risk Management' given on 15 May 2002 at IIASA's Greenhouse Gas Initiative seminars. Risks of disaster arise out of the combination of natural hazards and human activities. We argue that by divorcing the natural disaster issues from social and economic development, half of this disaster equation is ignored. The current pace of disaster development is undermining the markets and safety nets not only of developing countries. Far greater policy coherence is needed between economists, development planners, natural scientists and disaster managers in order to prevent catastrophic losses to human lives, livelihoods, and natural and economic assets. In this paper we present an integrated approach to catastrophic risk management that aims at more coherence and comprehensiveness. The models presented take into account spatial and temporal heterogeneity of catastrophes as well as institutional heterogeneity within a model of economic growth. Loss and gains profiles are functions of various strategies/requirements/goals of agents such as individuals, governments, producers, insurers and investors. GIS-based catastrophe models and stochastic optimization methods allow to guide policy analyses with respect to location specific risk exposures.

  5. Rate-weakening friction characterizes both slow sliding and catastrophic failure of landslides.

    Science.gov (United States)

    Handwerger, Alexander L; Rempel, Alan W; Skarbek, Rob M; Roering, Joshua J; Hilley, George E

    2016-09-13

    Catastrophic landslides cause billions of dollars in damages and claim thousands of lives annually, whereas slow-moving landslides with negligible inertia dominate sediment transport on many weathered hillslopes. Surprisingly, both failure modes are displayed by nearby landslides (and individual landslides in different years) subjected to almost identical environmental conditions. Such observations have motivated the search for mechanisms that can cause slow-moving landslides to transition via runaway acceleration to catastrophic failure. A similarly diverse range of sliding behavior, including earthquakes and slow-slip events, occurs along tectonic faults. Our understanding of these phenomena has benefitted from mechanical treatments that rely upon key ingredients that are notably absent from previous landslide descriptions. Here, we describe landslide motion using a rate- and state-dependent frictional model that incorporates a nonlocal stress balance to account for the elastic response to gradients in slip. Our idealized, one-dimensional model reproduces both the displacement patterns observed in slow-moving landslides and the acceleration toward failure exhibited by catastrophic events. Catastrophic failure occurs only when the slip surface is characterized by rate-weakening friction and its lateral dimensions exceed a critical nucleation length [Formula: see text] that is shorter for higher effective stresses. However, landslides that are extensive enough to fall within this regime can nevertheless slide slowly for months or years before catastrophic failure. Our results suggest that the diversity of slip behavior observed during landslides can be described with a single model adapted from standard fault mechanics treatments.

  6. Planning for persistence in marine reserves: a question of catastrophic importance.

    Science.gov (United States)

    Game, Edward T; Watts, Matthew E; Wooldridge, Scott; Possingham, Hugh P

    2008-04-01

    Large-scale catastrophic events, although rare, lie generally beyond the control of local management and can prevent marine reserves from achieving biodiversity outcomes. We formulate a new conservation planning problem that aims to minimize the probability of missing conservation targets as a result of catastrophic events. To illustrate this approach we formulate and solve the problem of minimizing the impact of large-scale coral bleaching events on a reserve system for the Great Barrier Reef, Australia. We show that by considering the threat of catastrophic events as part of the reserve design problem it is possible to substantially improve the likely persistence of conservation features within reserve networks for a negligible increase in cost. In the case of the Great Barrier Reef, a 2% increase in overall reserve cost was enough to improve the long-run performance of our reserve network by >60%. Our results also demonstrate that simply aiming to protect the reefs at lowest risk of catastrophic bleaching does not necessarily lead to the best conservation outcomes, and enormous gains in overall persistence can be made by removing the requirement to represent all bioregions in the reserve network. We provide an explicit and well-defined method that allows the probability of catastrophic disturbances to be included in the site selection problem without creating additional conservation targets or imposing arbitrary presence/absence thresholds on existing data. This research has implications for reserve design in a changing climate.

  7. Catastrophe Bonds. From Structure to Strategy – A Cluster Analysis at European Level

    Directory of Open Access Journals (Sweden)

    Laura-Gabriela CONSTANTIN

    2014-12-01

    Full Text Available As a core activity and discipline of corporate management and corporate governance, risk management is, especially nowadays, a central part in pursuing the sustainable development desiderates, both from the perspective of the firm and of the society as a whole.Considering the negative impact natural catastrophes have on the companies’ and countries’ competitiveness, the development of sustainable financial products that make a contribution to transferring the risk and allocating the capital in case of disasters stands for a continual preoccupation, especially for the (reinsurance industry, while the study of catastrophe bonds – insurance-linked securities – is of interest in the specialized literature. In this context, the scope of the present research is to expand the empirical studies within this field while examining the link between the structure of the catastrophe bonds and the risk management approach employed while accessing the capital markets through this transactions.The methodology entailed clustering a selection of transactions developed by European cedents based on the size of each issue and correlating the results with an innovative score, developed to encompass several important catastrophe bonds structural components.The findings reflect that the general structural elements of the financial transactions reflect closely the corporate approach regarding the innovative risk intermediation instruments for the examined catastrophe bonds deals. The outcomes also emphasize, as expected, that companies with a stronger presence on this market seem to have a more sophisticated risk management approach.

  8. Catastrophe model and its experimental verification of static loading rock system under impact load

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    According to the catastrophe model for impact buckling of static loading structures, a new catastrophe model for impact loading failure of a static loading rock system was established, and one dimension (1D) catastrophe model was analyzed. The analysis results indicate that the furcation collection where catastrophe may take place is not only decided by mechanical system itself but also relates to exterior loading, which is different from the results obtained under mono-static loading where the bifurcation collection is only determined by mechanics of the system itself and has nothing to do with exterior loading. In addition, the corresponding 1D coupled static-dynamic loading experiment is designed to verify the analysis results of catastrophe model The test is done with Instron 1342 electroservo controlled testing system, in which medium strain rate is caused by monotony rising dynamic load. The parameters are obtained combining theoretical model with experiment. The experimental and theoretical curves of critical dynamic load vs static load are rather coincided, thus the new model is proved to be correct.

  9. Rate-weakening friction characterizes both slow sliding and catastrophic failure of landslides

    Science.gov (United States)

    Handwerger, Alexander L.; Rempel, Alan W.; Skarbek, Rob M.; Roering, Joshua J.; Hilley, George E.

    2016-09-01

    Catastrophic landslides cause billions of dollars in damages and claim thousands of lives annually, whereas slow-moving landslides with negligible inertia dominate sediment transport on many weathered hillslopes. Surprisingly, both failure modes are displayed by nearby landslides (and individual landslides in different years) subjected to almost identical environmental conditions. Such observations have motivated the search for mechanisms that can cause slow-moving landslides to transition via runaway acceleration to catastrophic failure. A similarly diverse range of sliding behavior, including earthquakes and slow-slip events, occurs along tectonic faults. Our understanding of these phenomena has benefitted from mechanical treatments that rely upon key ingredients that are notably absent from previous landslide descriptions. Here, we describe landslide motion using a rate- and state-dependent frictional model that incorporates a nonlocal stress balance to account for the elastic response to gradients in slip. Our idealized, one-dimensional model reproduces both the displacement patterns observed in slow-moving landslides and the acceleration toward failure exhibited by catastrophic events. Catastrophic failure occurs only when the slip surface is characterized by rate-weakening friction and its lateral dimensions exceed a critical nucleation length h*h* that is shorter for higher effective stresses. However, landslides that are extensive enough to fall within this regime can nevertheless slide slowly for months or years before catastrophic failure. Our results suggest that the diversity of slip behavior observed during landslides can be described with a single model adapted from standard fault mechanics treatments.

  10. Catastrophic wind damage to North American forests and the potential impact of climate change.

    Science.gov (United States)

    Peterson, C J

    2000-11-15

    Catastrophic winds from tornadoes and downbursts are a major cause of natural disturbance in forests of eastern North America, accounting for thousands of hectares of disturbed area annually. Wind disturbance shows substantial regional variation, decreasing from the mid-west to the east and from the south-east to New England. In terms of the relative importance among these types of storms, more forest damage results from tornadoes in the south-east and mid-west, while downbursts are the most important type of wind disturbance in the Great Lakes area. Downbursts vary widely in size, but large ones can damage thousands of hectares, while tornadoes are much smaller, seldom affecting more than several hundred hectares. Tornadoes cause the most severe wind disturbances. Site characteristics such as physiography, soil moisture, and soil depth; stand characteristics like density and canopy roughness; and tree characteristics such as size, species, rooting depth, and wood strength, are the factors most recognized as influencing damage patterns. The consequences of wind damage to forests, such as change in environmental conditions, density, size structure, species composition, and successional status, occur on both immediate (hours-to-days) and long-term (months-to-decades) time scales. Most wind disturbances result in the post-disturbance vegetation being comprised of surviving canopy trees, and varying amounts of sprouts, released understory stems, and new seedlings. Stand size structure is usually reduced, and successional status of a forest is often advanced. Diversity can be either increased or decreased, depending on the measure of abundance used to calculate diversity. Because tornadoes and downbursts are in part products of thermodynamic climatic circumstances, they may be affected by anticipated changes in climatic conditions as the 21st century progresses. However, the current understanding of tornado and downburst formation from supercell storms is very

  11. Catastrophic wind damage to North American forests and the potential impact of climate change

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, C.J. [Department of Botany, 2502 Plant Sciences Building, University of Georgia, Athens, GA 30602-7271 (United States)

    2000-11-15

    Catastrophic winds from tornadoes and downbursts are a major cause of natural disturbance in forests of eastern North America, accounting for thousands of hectares of disturbed area annually. Wind disturbance shows substantial regional variation, decreasing from the mid-west to the east and from the south-east to New England. In terms of the relative importance among these types of storms, more forest damage results from tornadoes in the south-east and mid-west, while downbursts are the most important type of wind disturbance in the Great Lakes area. Downbursts vary widely in size, but large ones can damage thousands of hectares, while tornadoes are much smaller, seldom affecting more than several hundred hectares. Tornadoes cause the most severe wind disturbances. Site characteristics such as physiography, soil moisture, and soil depth; stand characteristics like density and canopy roughness; and tree characteristics such as size, species, rooting depth, and wood strength, are the factors most recognized as influencing damage patterns. The consequences of wind damage to forests, such as change in environmental conditions, density, size structure, species composition, and successional status, occur on both immediate (hours-to-days) and long-term (months-to-decades) time scales. Most wind disturbances result in the post-disturbance vegetation being comprised of surviving canopy trees, and varying amounts of sprouts, released understory stems, and new seedlings. Stand size structure is usually reduced, and successional status of a forest is often advanced. Diversity can be either increased or decreased, depending on the measure of abundance used to calculate diversity. Because tornadoes and downbursts are in part products of thermodynamic climatic circumstances, they may be affected by anticipated changes in climatic conditions as the 21st century progresses. However, the current understanding of tornado and downburst formation from supercell storms is very

  12. Targeting pain catastrophization in patients with fibromyalgia using virtual reality exposure therapy: a proof-of-concept study

    OpenAIRE

    Morris, Linzette Deidrè; Louw, Quinette Abegail; Grimmer, Karen Anne; Meintjes, Ernesta

    2015-01-01

    [Purpose] Pain catastrophizing is a key predictor of poor compliance to exercises among patients with fibromyalgia syndrome. Alteration of pain catastrophizing in this group is thus warranted. This study aimed to provide proof-of-concept of a novel virtual reality exposure therapy program as treatment for exercise-related pain catastrophizing in patients with fibromyalgia syndrome. [Subjects and Methods] An exploratory, case-controlled study was conducted (fibromyalgia syndrome group and matc...

  13. After the Fall: The Tapestry of Disturbance and Recovery.

    Science.gov (United States)

    Nadkarni, Nalini M

    2017-02-01

    On July 3, 2015, Nalini Nadkarni, a world-renowned ecologist who had been studying the biologic processes of ecosystem disturbance and recovery, sustained a catastrophic 50-foot free-fall from the top of the rainforest canopy to the forest floor at her remote field research site. She lost consciousness in shock and sustained life-threatening injuries. Her accompanying students hiked out, radio-called 911, and the Harborview Medical Center (Seattle) Medivac team arrived 4 hours later to rescue her. Her prognosis was extremely grim; her family gathered in anticipation of her death as she underwent four operations during her 10 days in the ICU. As she emerged from coma, she spent weeks of hospital recovery and months of progressive mobility and physical therapy during medical leave from work. She experienced ICU psychosis and postintensive care syndrome, but slowly recovered nearly totally, to the point where she can solo hike up to 18 miles in a day, and has fully resumed her professional responsibilities as professor of biology, including climbing tall trees for her canopy research. She attributes her survival and remarkable recovery to both exquisite medical critical care and support she received, and also to incorporating lessons learned from her interdisciplinary study of how diverse natural systems commonly experience and recover from catastrophic disturbances (e.g., forest fires, traffic jams, orphaned children, and refugee survivors of war). Insights from her own encounter with critical illness and study of disturbance and recovery led her to reflect on the tapestry of disturbance and recovery that permeate all ecosystems, and with relevance to the evolving Society of Critical Care Medicine, postintensive care syndrome, and THRIVE initiatives.

  14. Improving Recovery from Catastrophic Bone Injuries: An Animal Model for Assessing the Bone Reparative Potential of Progenitor Cell Therapy

    Science.gov (United States)

    2009-08-01

    Liu, Y. Strecker, S., Wang, L., Kronenberg , M., Kalajzic, I. and Rowe, D. Characterizing the Osteogenic Potential of Mesenchymal Stem Cells and...Their Immediate Cellular Derivatives. J. Bone. Min. Res. 24: Suppl 1, Abst SA0220, 2009. 3. Kronenberg , M., Harrison, J., Ravi, N., Shin, D. and Rowe, D...Abst SA0227, 2009. 4. Harrison, J., Kronenberg , M. and Rowe, D. Tracking Expression of a Smooth Muscle Alpha- Actin-Red Fluorescent Protein (SMAA-RFP

  15. Grazing incidence beam expander

    Energy Technology Data Exchange (ETDEWEB)

    Akkapeddi, P.R.; Glenn, P.; Fuschetto, A.; Appert, Q.; Viswanathan, V.K.

    1985-01-01

    A Grazing Incidence Beam Expander (GIBE) telescope is being designed and fabricated to be used as an equivalent end mirror in a long laser resonator cavity. The design requirements for this GIBE flow down from a generic Free Electron Laser (FEL) resonator. The nature of the FEL gain volume (a thin, pencil-like, on-axis region) dictates that the output beam be very small. Such a thin beam with the high power levels characteristic of FELs would have to travel perhaps hundreds of meters or more before expanding enough to allow reflection from cooled mirrors. A GIBE, on the other hand, would allow placing these optics closer to the gain region and thus reduces the cavity lengths substantially. Results are presented relating to optical and mechanical design, alignment sensitivity analysis, radius of curvature analysis, laser cavity stability analysis of a linear stable concentric laser cavity with a GIBE. Fabrication details of the GIBE are also given.

  16. CATASTROPHIC ECO-ENVIRONMENTAL CHANGE IN THE SONGNEN PLAIN, NORTHEASTERN CHINA SINCE 1900S

    Institute of Scientific and Technical Information of China (English)

    WANG Hai-xia; WAN Zhong-juan; YU Shao-peng; LUO Xin-zheng; SUN Guang-you

    2004-01-01

    Although the Songnen Plain in the northeastern China was developed relatively late in the temperate zone of the world, its eco-environment has changed greatly. This paper analyzes the changes of land cover and the rates and trends ofdesertification during the past 100 years in the Songnen Plain. According to the macroscopic analysis, we find that the eco-environment in the plain has reached to the threshold of catastrophic change since the 1950s. The Thom Needle Catastrophic Model was used to determine and validate this conclusion. Human activities, including large-scale construction projects, such as huge dams and dikes, and excessive grazing were the primary factors contributing to regional eco-environmental catastrophe. And irrational reclamation of the wilderness also affected the eco-environmental change. The results reveal the complex human-land interactions.

  17. Evaluation of the propensity for coal spontaneous combustion based on catastrophe theory

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yu-tao; ZHANG Xi-chen; TIEN Jerry C; LI Ya-qing

    2011-01-01

    Generally,different prevention measures should be taken according to spontaneous combustion propensities.The current methods to evaluate the propensity of coal spontaneous combustion,such as chromatographic method of oxygen adsorption,oxidation kinetics method and activation energy method,are mostly affected by human factors.Their boundaries among different classes of propensities were all established by subjective judgments.A new evaluation method using catastrophe theory is introduced.This method can accurately depict the process of coal spontaneous combustion and the evaluation index,"catastrophe temperature",be obtained based on the model.In terms of catastrophe temperature,the spontaneous combustion propensity of different coals can be sequenced.Experimental data indicate that this method is appropriate to describe the spontaneous combustion process and to evaluate the propensity of coal spontaneous combustion.

  18. Tailored disconnection based on presurgical evidence in catastrophic epilepsy: report of 2 cases.

    Science.gov (United States)

    Park, Jun T; Manjila, Sunil V; Tangen, Rachel B; Cohen, Mark L; Shahid, Asim M; Sweet, Jennifer A; Tuxhorn, Ingrid E; Miller, Jonathan P

    2016-06-01

    Catastrophic epilepsy in infants, often due to extensive cortical dysplasia, has devastating consequences with respect to brain development. Conventional lobar, multilobar, or hemispheric resection in these infants is challenging, carrying an increased operative risk compared with that in older children. Removing a larger tissue volume versus removing or disconnecting the epileptogenic region does not always guarantee better seizure outcome. The authors describe 2 infants with catastrophic epilepsy who benefited from individually tailored disconnections based on a hypothesized epileptogenic zone following intensive presurgical evaluation. Two infants with catastrophic epilepsy and epileptic spasms underwent leukotomies between 3 and 12 months of age. They were followed up postoperatively for 19-36 months. Both patients had 90%-100% seizure reduction and a significantly improved neurodevelopmental outcome without postoperative complication. Cortical malformation was seen in both patients. Modifications of established surgical disconnection techniques, tailored to each patient's specific epileptogenic zone, optimized seizure and neurodevelopmental outcomes while minimizing the risks associated with more extensive resections.

  19. CALIFORNIA STATE UNIVERSITY CATASTROPHIC (CAT) LEAVE DONATION PROGRAM: DEMOGRAPHICS, ECONOMIC SECURITY, AND SOCIAL EQUITY.

    Science.gov (United States)

    Muller, Christina

    2015-01-01

    The California State University (CSU) Chancellor's Office reached an agreement with all CSU collective bargaining units and Employee Relations on a uniform Catastrophic (CAT) Leave Donation Program in 1992. The CAT Leave Donation Program allows employees to donate sick and/or vacation leave credits to employees who are incapacitated due to a catastrophic illness or injury and have exhausted all of their own leave credits. This also extends to employees with whom family illnesses are deemed catastrophic, thus requiring the employee to care for an immediate family member. Stakeholders include union represented employees who accrue leave credits as well as any employee who receives or donates hours of leave credits in the program. Other stakeholders include the family members and program administrators.

  20. On the foreshocks of strong earthquakes in the light of catastrophe theory

    CERN Document Server

    Guglielmi, A V; Sobisevich, L E; Lavrov, I P

    2013-01-01

    It is useful to consider the earthquakes in terms of catastrophe theory. In the paper, we illustrate this statement by analysis foreshocks preceding the strong earthquakes. We focused on the so-called catastrophe flags, and on the triggers that cause the critical transitions. The analysis shows a sharp increase of foreshock activity 3 h before the mainshock. This result is reminiscent of the well-known activation of the ULF magnetic precursors of earthquakes. Furthermore, we found that the characteristic frequency of foreshock sequence decreases a few hours before the mainshock, which is consistent with a prediction of the catastrophe theory. Finally, the analysis testifies that the strong foreshocks seems may be triggers of mainshocks. The idea is that the surface waves propagating outwards from the foreshock return back to the vicinity of the epicenter after having made a complete revolution around the Earth and induce there the mainshock.

  1. Analgesic effect of perioperative escitalopram in high pain catastrophizing patients after total knee arthroplasty

    DEFF Research Database (Denmark)

    Lunn, Troels H; Frokjaer, Vibe G; Hansen, Torben Bæk

    2015-01-01

    has not previously been investigated. The authors hypothesized that perioperative escitalopram would reduce pain after TKA in high pain catastrophizing patients. METHODS: A total of 120 pain catastrophizing patients (selected using the pain catastrophizing scale as preoperative screening tool......) scheduled for TKA were randomized in a double-blind manner to either 10 mg escitalopram or placebo daily from preanesthesia to postoperative day 6 in addition to a standardized analgesic regime. The primary outcome was pain upon ambulation 24 h after surgery. Secondary outcomes were overall pain during well......-defined mobilizations and at rest from 2 to 48 h and from days 2 to 6, morphine equivalents, anxiety, depression, and side effects. RESULTS: Pain upon ambulation (mean [95% CI]) 24 h after surgery in the escitalopram versus placebo group was 58 (53 to 64) versus 64 (58 to 69), the mean difference being -5 (-13 to 3), P...

  2. Household catastrophic healthcare expenditure and impoverishment due to rotavirus gastroenteritis requiring hospitalization in Malaysia.

    Directory of Open Access Journals (Sweden)

    Tharani Loganathan

    Full Text Available While healthcare costs for rotavirus gastroenteritis requiring hospitalization may be burdensome on households in Malaysia, exploration on the distribution and catastrophic impact of these expenses on households are lacking.We assessed the economic burden, levels and distribution of catastrophic healthcare expenditure, the poverty impact on households and inequities related to healthcare payments for acute gastroenteritis requiring hospitalization in Malaysia.A two-year prospective, hospital-based study was conducted from 2008 to 2010 in an urban (Kuala Lumpur and rural (Kuala Terengganu setting in Malaysia. All children under the age of 5 years admitted for acute gastroenteritis were included. Patients were screened for rotavirus and information on healthcare expenditure was obtained.Of the 658 stool samples collected at both centers, 248 (38% were positive for rotavirus. Direct and indirect costs incurred were significantly higher in Kuala Lumpur compared with Kuala Terengganu (US$222 Vs. US$45; p<0.001. The mean direct and indirect costs for rotavirus gastroenteritis consisted 20% of monthly household income in Kuala Lumpur, as compared with only 5% in Kuala Terengganu. Direct medical costs paid out-of-pocket caused 141 (33% households in Kuala Lumpur to experience catastrophic expenditure and 11 (3% households to incur poverty. However in Kuala Terengganu, only one household (0.5% experienced catastrophic healthcare expenditure and none were impoverished. The lowest income quintile in Kuala Lumpur was more likely to experience catastrophic payments compared to the highest quintile (87% vs 8%. The concentration index for out-of-pocket healthcare payments was closer to zero at Kuala Lumpur (0.03 than at Kuala Terengganu (0.24.While urban households were wealthier, healthcare expenditure due to gastroenteritis had more catastrophic and poverty impact on the urban poor. Universal rotavirus vaccination would reduce both disease burden and health

  3. 36-Year-Old Female with Catastrophic Antiphospholipid Syndrome Treated with Eculizumab: A Case Report and Review of Literature

    Directory of Open Access Journals (Sweden)

    Marianna Strakhan

    2014-01-01

    Full Text Available Catastrophic antiphospholipid syndrome (CAPS is a rare but potentially life-threatening condition characterized by diffuse vascular thrombosis, leading to multiple organ failure developing over a short period of time in the presence of positive antiphospholipid antibodies (aPL. CAPS is a severe form of antiphospholipid syndrome, developing in about 1% of cases of classic antiphospholipid syndrome, manifesting as microangiopathy, affecting small vessels of multiple organs. It is acute in onset, with majority of cases developing thrombocytopenia and less frequently hemolytic anemia and disseminated intravascular coagulation. Lupus anticoagulant and anticardiolipin antibodies have been reported as predominant antibodies associated with CAPS. Treatment options often utilized in CAPS include anticoagulation, steroids, plasma exchange, cyclophosphamide therapy, and intravenous immunoglobulin therapy. Even though the reported incidence of this condition is considered to be low, the mortality rate is approaching 50%. The high rate of mortality should warrant greater awareness among clinicians for timely diagnosis and treatment of this life-threatening condition. Studies have shown that complement activation plays a key role in the pathogenesis of aPL mediated thrombosis in CAPS. We report a case of a 36-year-old female admitted with clinical and laboratory findings consistent with CAPS successfully treated with eculizumab, a terminal complement inhibitor.

  4. The World Trade Center Attack: Helping the helpers: the role of critical incident stress management

    OpenAIRE

    Hammond, Jeffrey; Brooks, Jill

    2001-01-01

    Healthcare and prehospital workers involved in disaster response are susceptible to a variety of stress-related psychological and physical sequelae. Critical incident stress management, of which critical incident stress debriefing is a component, can mitigate the response to these stressors. Critical incident stress debriefing is a peer-driven, therapist-guided, structured, group intervention designed to accelerate the recovery of personnel. The attack on the World Trade Center, and the impac...

  5. Model and algorithm for optimization of rescue center location of emergent catastrophe

    Institute of Scientific and Technical Information of China (English)

    WANG Ding-wei; ZHANG Guo-xiang

    2006-01-01

    The location of rescue centers is a key problem in optimal resource allocation and logistics in emergency response.We propose a mathematical model for rescue center location with the considerations of emergency occurrence probability,catastrophe diffusion function and rescue function.Because the catastrophe diffusion and rescue functions are both nonlinear and time-variable,it cannot be solved by common mathematical programming methods.We develop a heuristic embedded genetic algorithm for the special model solution.The computation based on a large number of examples with practical data has shown us satisfactory results.

  6. Requiem for analytical psychology: a reflection on Jung's (anti)catastrophic psychology.

    Science.gov (United States)

    Barreto, Marco Heleno

    2014-02-01

    This article is an interpretation of analytical psychology in the light of the catastrophic vision and dreams that Jung had in 1913 and 1914. It is shown how the guiding spirit of Jung's psychological project is to be found in that psychic material. Then it is proposed that the completion of the symbolic catastrophe displayed in Jung's last vision (1961) points to the end of the psychological foundations upon which analytical psychology is built, and thus to its cultural obsolescence, extensive to any psychology grounded in Jung's notion of 'soul'.

  7. Imaging findings in the rare catastrophic variant of the primary antiphospholipid syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Thuerl, Christina; Altehoefer, Carsten; Laubenberger, Joerg [Freiburg Univ. (Germany). Abt. Radiologie; Spyridonidis, Alexandros [Freiburg Univ. (DE). Abt. Innere Medizin 1 (Haematologie und Onkologie)

    2002-03-01

    We report imaging findings in a case of the rare catastrophic variant of antiphospholipid syndrome (CAPS) characterized by widespread microvascular occlusions, which may lead to multiple organ failure. We present a case of a 66-year-old woman with bone marrow necrosis, acute acalculous cholecystitis (AAC), focal liver necrosis, subtle patchy splenic infarctions, and bilateral adrenal infarction. The demonstration of multiple microvascular organ involvement (three or more) is crucial for the diagnosis of the catastrophic variant of APS. This can be performed radiologically intra-vitam. Imaging can even reveal subclinical microinfarctions, which are often only diagnosed at autopsy. (orig.)

  8. Pain catastrophizing as a risk factor for chronic pain after total knee arthroplasty: a systematic review

    Directory of Open Access Journals (Sweden)

    Burns LC

    2015-01-01

    Full Text Available Lindsay C Burns,1–3 Sarah E Ritvo,1 Meaghan K Ferguson,1 Hance Clarke,3–5 Ze’ev Seltzer,3,5 Joel Katz1,3–5 1Department of Psychology, York University, Toronto, ON, Canada; 2Arthritis Research Centre of Canada, Vancouver, BC, Canada; 3Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, ON, Canada; 4Department of Anesthesia, University of Toronto, Toronto, ON, Canada; 5Centre for the Study of Pain, Faculties of Dentistry and Medicine, University of Toronto, Toronto, ON, Canada Background: Total knee arthroplasty (TKA is a common and costly surgical procedure. Despite high success rates, many TKA patients develop chronic pain in the months and years following surgery, constituting a public health burden. Pain catastrophizing is a construct that reflects anxious preoccupation with pain, inability to inhibit pain-related fears, amplification of the significance of pain vis-à-vis health implications, and a sense of helplessness regarding pain. Recent research suggests that it may be an important risk factor for untoward TKA outcomes. To clarify this impact, we systematically reviewed the literature to date on pain catastrophizing as a prospective predictor of chronic pain following TKA. Methods: We searched MEDLINE, EMBASE, and PsycINFO databases to identify articles related to pain catastrophizing, TKA, risk models, and chronic pain. We reviewed titles and abstracts to identify original research articles that met our specified inclusion criteria. Included articles were then rated for methodological quality. including methodological quality. Due to heterogeneity in follow-up, analyses, and outcomes reported across studies, a quantitative meta-analysis could not be performed. Results: We identified six prospective longitudinal studies with small-to-mid-sized samples that met the inclusion criteria. Despite considerable variability in reported pain outcomes, pain catastrophizing was identified as a significant

  9. Climate change increases the likelihood of catastrophic avian mortality events during extreme heat waves.

    Science.gov (United States)

    McKechnie, Andrew E; Wolf, Blair O

    2010-04-23

    Severe heat waves have occasionally led to catastrophic avian mortality in hot desert environments. Climate change models predict increases in the intensity, frequency and duration of heat waves. A model of avian evaporative water requirements and survival times during the hottest part of day reveals that the predicted increases in maximum air temperatures will result in large fractional increases in water requirements (in small birds, equivalent to 150-200 % of current values), which will severely reduce survival times during extremely hot weather. By the 2080s, desert birds will experience reduced survival times much more frequently during mid-summer, increasing the frequency of catastrophic mortality events.

  10. Catastrophes and Conservation: Lessons from Sea Otters and the Exxon Valdez

    Directory of Open Access Journals (Sweden)

    Estes J.A.

    1992-02-01

    Full Text Available The Exxon Valdez spill is broadly perceived as an environmental catastrophe. However, expected catastrophic declines in the region's sea otter population cannot be demonstrated, not because they didn't occur but because the necessary information is lacking. Furthermore, efforts to rehabilitate oiled sea otters following the spill were extremely expensive and ineffective. Some improvements are possible with better planning. However, post-spill capture and rehabilitation probably can not be used to substantially reduce sea otter losses from future spills, and the use of such measures to conserve populations is unrealistic.

  11. EPA Recovery Mapper

    Data.gov (United States)

    U.S. Environmental Protection Agency — The EPA Recovery Mapper is an Internet interactive mapping application that allows users to discover information about every American Recovery and Reinvestment Act...

  12. Forecasting scenarios of collision catastrophes produced by celestial body falls

    Science.gov (United States)

    Shor, V.; Kochetova, O.; Chernetenko, Y.; Zheleznov, N.; Deryugin, V.; Zaitsev, A.

    2014-07-01

    The subject under discussion arose in the course of developing a computer program, which gives the possibility for numerical and graphical modeling of the scenarios of catastrophes caused by collisions of cosmic bodies with the Earth. It is expected that this program can be used for computer-assisted training of the personnel of units of the Ministry for Emergency Situations in the case of a situation caused by the fall of a celestial body on the Earth. Also, it is anticipated that the program can be used in real situations when a dangerous body is discovered on an orbit leading to an imminent collision with the Earth. From the scientific point of view, both variants of use require solving of analogous tasks. In what follows, we discuss both variants. 1. The computation of the circumstances for a fall on the Earth (or approach within short distance) of a real body begins with the determination of its orbit from the observations available using the least-squares method. The mean square error of the representation of the observations on the base of the initial values of the coordinates and the velocities is computed, as well as their covariance matrix. Then, the trajectory of the body's motion is followed by numerical integration starting from the osculating epoch to the collision with the Earth or to its flyby. The computer program takes into account the various cases: at the initial moment, the body can move away from or approach the Earth, it can be outside the sphere of action or inside it. At the moment, when the body enters the sphere of action, the coordinates of the center of the dispersion ellipse on the target plane are computed as well as the dimensions of its axes. Using these data, the probability of collision with the Earth is calculated. Then, the point of penetration of the body into the Earth's atmosphere at a given height above the level of the Earth geoid is determined. In case the body is passing by the Earth, the minimum distance of the body from

  13. From a Catastrophe Itself to Cata/strophic Reading. The Poetry of Charles Baudelaire in the Account of Jorge Semprúna L’écriture ou la vie

    Directory of Open Access Journals (Sweden)

    Judith Kasper

    2015-01-01

    Full Text Available This essay addresses the instable meaning of the term catastrophe over the course of history. The first part takes leave of the “the tiny fissures” in the continuous catastrophe noted by Walter Benjamin to develop a philology of the cata/strophe. This philology does not only register a given meaning (for instance, of the catastrophe, but intervenes actively as disruption. It insists on the strophe in the catastrophe, transforming catastrophe into cata/strophe that, in fatal situations, permits the poetic potential to become a dynamic force that can, at least on the linguistic level, open toward other dimensions without denying the catastrophe itself. The second part is dedicated to a reading of Jorge Semprún’s autobiographical novel L’écriture ou la vie from the perspective of this philological concept. It seeks to show how Semprún’s citing and reciting of Baudelaire’s strophes in the putrid atmosphere of the Buchenwald concentration camp literally produce, on the level of the signifiers, fresh air to breathe.

  14. Higher-dimensional catastrophes in nonlinear Compton scattering

    Science.gov (United States)

    Kharin, Vasily; Seipt, Daniel; Rykovanov, Sergey

    2016-10-01

    The Compton scattering of the light on the accelerated electron beam is a valuable tool for generating tunable wide range X- and γ-radiation.However, the cross-section of the scattering is relatively low. That is, in order to obtain bright X-rays one naturally may consider increasing the intensity of the incident light. Passing to relativistic values of laser intensity significantly changes scattering mechanism. Precise QED analysis of the scattered spectra leads to the study of the corresponding elements of S-matrix. Evaluation is usually performed numerically (except cases of specific pulse shapes and scattering angles). We argue that the problem of extracting the scattered spectra in nonlinear Compton scattering of the pulse can be reformulated in terms of studying properties of projection map of specific surfaces associated to the pulse. They are stable with respect to initial conditions, and the brightest regions of the spectrum appear to be in correspondence with the singularities of the projection map, also known as caustics in pure mathematics, diffraction optics and cosmology. Work was supported by the Helmholtz Association (Helmholtz Young Investigators group VH-NG-1037).

  15. Recovery from mental illness

    DEFF Research Database (Denmark)

    Petersen, Kirsten Schultz; Friis, Vivi Soegaard; Haxholm, Birthe Lodahl;

    2015-01-01

    Mental health services strive to implement a recovery-oriented approach to rehabilitation. Little is known about service users' perception of the recovery approach. The aim is to explore the service user's perspectives on facilitators and barriers associated with recovery. Twelve residents living...

  16. Removing a broken guidewire in the hip joint: treatment options and recommendations for preventing an avoidable surgical catastrophe. A case report

    Directory of Open Access Journals (Sweden)

    Abhijeet Ashok Salunke

    Full Text Available ABSTRACT CONTEXT: Hardware breakage during hip surgery can pose challenging and difficult problems for orthopedic surgeons. Apart from technical difficulties relating to retrieval of the broken hardware, complications such as adjacent joint arthritis and damage to neurovascular structures and major viscera can occur. Complications occurring during the perioperative period must be informed to the patient and proper documentation is essential. The treatment options must be discussed with the patient and relatives and the implant company must be informed about this untoward incident. CASE REPORT: We report a case of complete removal of the implant and then removal of the broken guidewire using a combination of techniques, including a cannulated drill bit, pituitary forceps and Kerrison rongeur. CONCLUSIONS: We suggest some treatment options and recommendations for preventing an avoidable surgical catastrophe.

  17. Sudden cardiac death in adults: causes, incidence and interventions.

    Science.gov (United States)

    Walker, Wendy Marina

    Many nurses will be familiar with the unexpected death of an adult patient following a sudden, life-threatening cardiac event. It is a situation that demands sensitive nursing care and skilled interventions to provide a foundation for recovery and promote healthy bereavement. This article examines the causes and incidence of sudden cardiac death in adults. Possible reactions of those who are suddenly bereaved are described and immediate care interventions aimed at dealing with the grief process are discussed. The article concludes by identifying ways in which the incidence of sudden cardiac death may be reduced.

  18. Disentangling phase transitions and critical points in the proton–neutron interacting boson model by catastrophe theory

    Directory of Open Access Journals (Sweden)

    J.E. García-Ramos

    2014-09-01

    Full Text Available We introduce the basic concepts of catastrophe theory needed to derive analytically the phase diagram of the proton–neutron interacting boson model (IBM-2. Previous studies [1–3] were based on numerical solutions. We here explain the whole IBM-2 phase diagram including the precise order of the phase transitions in terms of the cusp catastrophe.

  19. Disentangling phase transitions and critical points in the proton–neutron interacting boson model by catastrophe theory

    Energy Technology Data Exchange (ETDEWEB)

    García-Ramos, J.E., E-mail: enrique.ramos@dfaie.uhu.es [Departamento de Física Aplicada, Universidad de Huelva, 21071 Huelva (Spain); Unidad Asociada de la Universidad de Huelva al IEM (CSIC), Madrid (Spain); Arias, J.M., E-mail: ariasc@us.es [Departamento de Física Atómica, Molecular y Nuclear, Universidad de Sevilla, Apdo 1065, 41080 Sevilla (Spain); Unidad Asociada de la Universidad de Sevilla al IEM (CSIC), Madrid (Spain); Dukelsky, J., E-mail: dukelsky@iem.cfmac.csic.es [Instituto de Estructura de la Materia, CSIC, Serrano 123, 28006 Madrid (Spain)

    2014-09-07

    We introduce the basic concepts of catastrophe theory needed to derive analytically the phase diagram of the proton–neutron interacting boson model (IBM-2). Previous studies [1–3] were based on numerical solutions. We here explain the whole IBM-2 phase diagram including the precise order of the phase transitions in terms of the cusp catastrophe.

  20. Relationship of depression and catastrophizing to pain, disability, and medication adherence in patients with HIV-associated sensory neuropathy.

    Science.gov (United States)

    Lucey, Brendan P; Clifford, David B; Creighton, Jason; Edwards, Robert R; McArthur, Justin C; Haythornthwaite, Jennifer

    2011-08-01

    Few studies have examined how patients with chronic HIV infection cope with pain and how pain relates to medication adherence. Pain coping strategies such as catastrophizing are often associated with increased pain and disability and may also influence adherence to medications. The goal of our study is to assess the relationship of catastrophizing and depression to pain, disability, and medication adherence through questionnaires administered to a cross-section of patients with HIV-associated sensory neuropathy. In our study, 46 HIV-seropositive subjects completed questionnaires evaluating neuropathic pain severity, pain catastrophizing, pain-related disability, depressive symptoms, severity of antiretroviral therapy (ART) side effects, and common reasons for medication nonadherence. Hierarchical regression analysis indicated that pain catastrophizing correlated with severity of neuropathic pain independent of depressive symptoms. Furthermore, depressive symptoms were not associated with multiple factors independent of pain catastrophizing such as severity of neuropathic pain and pain-related disability. Pain catastrophizing, but not depressive symptoms, correlated with increased pain disability even after controlling for the effects of age and neuropathic pain. We also found that poor adherence attributed to fear of side effects or forgetfulness was associated with increased severity of neuropathic pain, while depressive symptoms but not catastrophizing correlated with ART side effects. These findings suggest that both catastrophizing and depressive symptoms are important factors to consider in the management of pain from HIV neuropathy and adherence to ART.

  1. 灾难性医疗支出研究%Study on Catastrophic Health Expenditure

    Institute of Scientific and Technical Information of China (English)

    褚福灵

    2016-01-01

    Catastrophic heath expenditure occurs when the total out-of-pocket health payments are ≥40%of the household’s capacity to pay(non-living expenses). Studies have showed that the highest rate of catastrophic payments was 13%% in the world, and there were about 5% of poverty caused by serious illness. We should calculate the rate of catastrophic payment and poverty due to illness by using normative methods, and adopt comprehensive measures to prevent the occurrence of catastrophic health expenditure.%家庭的医疗费用支出等于或超过家庭支付能力(非生存支出)的40%时,该家庭即发生了灾难性医疗支出。世界范围内,家庭灾难性医疗支出发生率最高为13%,因病致贫发生率最高为5%。应采用规范的方法测算灾难性医疗支出发生率与因病致贫率,并采取综合措施防范灾难性医疗风险的发生。

  2. SOIL CONTAMINATION CAUSED BY EMERGENCY BIO-REDUCTION OF CATASTROPHIC LIVESTOCK MORTALITIES

    Science.gov (United States)

    Catastrophic regional losses of poultry and livestock have caused environmental officials in North America to seek emergency on-farm disposal alternatives that pose less pollution risk to soil and shallow groundwater than burial. Bio-decomposition of remains followed by land application of the resul...

  3. THE NONLINEAR CUSP-CATASTROPHE MODEL OF THE SEDIMENT TRANSPORT RATE

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In the catastrophe theory of nonlinear science,the intensity of water-flow and the coefficient of non-uniformsediment m are regarded as two bound variables, and the in-tensity of bed-load transport Φ as the state variable in the mo-tion of non-uniform sediment in cusp-catastrophe model.Based on the standard equation of the cusp-catastrophe theo-ry, the relation equation between the intensity of bed-loadtransport Φ and the intensity of water-flow has been derivedby used coordinate transform and topology transform. The e-quation of bed load transport rate was built on the cusp-catas-trophe theory of nonlinear science. The others are applied toverify this equation, that the results calculated by the cusp-ca-tastrophe equation agree well with the other equations. Thisindicates that the cusp-catastrophe equation is reasonable, and the results fully reflect the characteristics of threshold motionand transport of non-uniform sediment. The purpose of thispaper is to explore the incipient motion and transport laws ofnon-uniform sediment from the viewpoint of nonlinear science.

  4. Expected Utility and Catastrophic Risk in a Stochastic Economy-Climate Model

    NARCIS (Netherlands)

    Ikefuji, M.; Laeven, R.J.A.; Magnus, J.R.; Muris, C.H.M.

    2010-01-01

    In the context of extreme climate change, we ask how to conduct expected utility analysis in the presence of catastrophic risks. Economists typically model decision making under risk and uncertainty by expected util- ity with constant relative risk aversion (power utility); statisticians typi- cally

  5. Subamolide a induces mitotic catastrophe accompanied by apoptosis in human lung cancer cells.

    Science.gov (United States)

    Hung, Jen-Yu; Wen, Ching-Wen; Hsu, Ya-Ling; Lin, En-Shyh; Huang, Ming-Shyan; Chen, Chung-Yi; Kuo, Po-Lin

    2013-01-01

    This study investigated the anticancer effects of subamolide A (Sub-A), isolated from Cinnamomum subavenium, on human nonsmall cell lung cancer cell lines A549 and NCI-H460. Treatment of cancer cells with Sub-A resulted in decreased cell viability of both lung cancer cell lines. Sub-A induced lung cancer cell death by triggering mitotic catastrophe with apoptosis. It triggered oxidant stress, indicated by increased cellular reactive oxygen species (ROS) production and decreased glutathione level. The elevated ROS triggered the activation of ataxia-telangiectasia mutation (ATM), which further enhanced the ATF3 upregulation and subsequently enhanced p53 function by phosphorylation at Serine 15 and Serine 392. The antioxidant, EUK8, significantly decreased mitotic catastrophe by inhibiting ATM activation, ATF3 expression, and p53 phosphorylation. The reduction of ATM and ATF3 expression by shRNA decreased Sub-A-mediated p53 phosphorylation and mitotic catastrophe. Sub-A also caused a dramatic 70% reduction in tumor size in an animal model. Taken together, cell death of lung cancer cells in response to Sub-A is dependent on ROS generation, which triggers mitotic catastrophe followed by apoptosis. Therefore, Sub-A may be a novel anticancer agent for the treatment of nonsmall cell lung cancer.

  6. Subamolide A Induces Mitotic Catastrophe Accompanied by Apoptosis in Human Lung Cancer Cells

    Directory of Open Access Journals (Sweden)

    Jen-Yu Hung

    2013-01-01

    Full Text Available This study investigated the anticancer effects of subamolide A (Sub-A, isolated from Cinnamomum subavenium, on human nonsmall cell lung cancer cell lines A549 and NCI-H460. Treatment of cancer cells with Sub-A resulted in decreased cell viability of both lung cancer cell lines. Sub-A induced lung cancer cell death by triggering mitotic catastrophe with apoptosis. It triggered oxidant stress, indicated by increased cellular reactive oxygen species (ROS production and decreased glutathione level. The elevated ROS triggered the activation of ataxia-telangiectasia mutation (ATM, which further enhanced the ATF3 upregulation and subsequently enhanced p53 function by phosphorylation at Serine 15 and Serine 392. The antioxidant, EUK8, significantly decreased mitotic catastrophe by inhibiting ATM activation, ATF3 expression, and p53 phosphorylation. The reduction of ATM and ATF3 expression by shRNA decreased Sub-A-mediated p53 phosphorylation and mitotic catastrophe. Sub-A also caused a dramatic 70% reduction in tumor size in an animal model. Taken together, cell death of lung cancer cells in response to Sub-A is dependent on ROS generation, which triggers mitotic catastrophe followed by apoptosis. Therefore, Sub-A may be a novel anticancer agent for the treatment of nonsmall cell lung cancer.

  7. Morphological response of a barrier island system on a catastrophic event

    DEFF Research Database (Denmark)

    Fruergaard, Mikkel; Kroon, Aart

    2016-01-01

    The AD 1634 North Sea storm is one of the most catastrophic storms along the Wadden Sea coast of Denmark. In this study we show how pre-1634 storm morphology exerted a strong control on the resulting post-storm coastal morphology. Erosional responses associated with the storm were barrier breachi...

  8. Do we need a communal coping model of pain catastrophizing? An alternative explanation

    NARCIS (Netherlands)

    Severeijns, R.; Vlaeyen, J.W.S.; Hout, M.A. van den

    2006-01-01

    In this topical review, a case is made for placing pain catastrophizing within the transactional stress and coping model of Lazarus and Folkman (1984). It is argued that the CCM in its current formulation might actually contribute to the conceptual confusion around the construct of pain catastrophiz

  9. The nonlinear dynamical hypothesis in science education problem solving: a catastrophe theory approach.

    Science.gov (United States)

    Stamovlasis, Dimitrios

    2006-01-01

    The current study tests the nonlinear dynamical hypothesis in science education problem solving by applying catastrophe theory. Within the neo-Piagetian framework a cusp catastrophe model is proposed, which accounts for discontinuities in students' performance as a function of two controls: the functional M-capacity as asymmetry and the degree of field dependence/independence as bifurcation. The two controls have functional relation with two opponent processes, the processing of relevant information and the inhibitory process of dis-embedding irrelevant information respectively. Data from achievement scores of freshmen at a technological college were measured at two points in time, and were analyzed using dynamic difference equations and statistical regression techniques. The cusp catastrophe model proved superior (R(2)=0.77) comparing to the pre-post linear counterpart (R(2)=0.46). Besides the empirical evidence, theoretical analyses are provided, which attempt to build bridges between NDS-theory concepts and science education problem solving and to neo-Piagetian theories as well. This study sets a framework for the application of catastrophe theory in education.

  10. Potential for Application of a Probabilistic Catastrophe Risk Modelling Framework to Poverty Outcomes

    OpenAIRE

    2016-01-01

    This paper analyzes the potential to combine catastrophe risk modelling (CAT risk modeling) with economic analysis of vulnerability to poverty using the example of drought hazard impacts on the welfare of rural households in Ethiopia. The aim is to determine the potential for applying a derived set of damage (vulnerability) functions based on realized shocks and household expenditure/consu...

  11. Folding catastrophes due to viscosity in multiferroic domains: implications for room-temperature multiferroic switching

    Science.gov (United States)

    Scott, J. F.

    2015-12-01

    Unusual domains with curved walls and failure to satisfy the Landau-Lifshitz-Kittel Law are modeled as folding catastrophes (saddle-node bifurcations). This description of ballistic motion in a viscous medium is based upon early work by Dawber et al 2003 Appl. Phys. Lett. 82 436. It suggests that ferroelectric films can exhibit folds or vortex patterns but not both.

  12. The 13 August 2010 catastrophic debris flows after the 2008 Wenchuan earthquake, China

    NARCIS (Netherlands)

    Xu, Q.; Zhang, S.; Li, W.L.; Asch, Th.W.J. van

    2012-01-01

    From 12 to 14 August 2010, heavy rainstorms occurred in the Sichuan province in SW China in areas which were affected by the 2008 Wenchuan Earthquake, inducing catastrophic debris flows. This disaster is named as “the 8.13 debris flows”. The results of the research presented in this paper show that

  13. Perceptions of Challenge: The Role of Catastrophe Theory in Piano Learning

    Science.gov (United States)

    Bugos, Jennifer; Lee, William

    2015-01-01

    The purpose of this study is to evaluate the perceptions of private piano instructors on the role of challenge in teaching and learning the piano and to examine the potential application of catastrophe theory in understanding the role and outcomes of such challenges. A 23-item electronic questionnaire was administered to collect quantitative and…

  14. Rapid growth of an infectious intracranial aneurysm with catastrophic intracranial hemorrhage.

    Science.gov (United States)

    Koffie, Robert M; Stapleton, Christopher J; Torok, Collin M; Yoo, Albert J; Leslie-Mazwi, Thabele M; Codd, Patrick J

    2015-03-01

    Infectious intracranial aneurysms are rare vascular lesions that classically occur in patients with infective endocarditis. We present a 49-year-old man with altered mental status and headache with rapid growth and rupture of an infectious intracranial aneurysm with catastrophic intracranial hemorrhage, and review issues related to open neurosurgical and endovascular interventions.

  15. Stochastic simulation of catastrophic hail and windstorm indemnities in the Dutch greenhouse sector

    NARCIS (Netherlands)

    Asseldonk, van M.A.P.M.; Meuwissen, M.P.M.; Huirne, R.B.M.

    2001-01-01

    A risk analysis was performed to examine the effect of changes in the Dutch greenhouse sector on the probability of occurrence and magnitude of indemnities induced by catastrophic natural hazards. Analyzed historical indemnities, which included direct and consequential losses resulting from severe h

  16. A Call to Action: Responding to Large-Scale Disasters, Catastrophes, and Traumas

    Science.gov (United States)

    Parham, William D.

    2011-01-01

    The ascendance of large-scale disasters, catastrophes, and traumas as a concentrated focus of academic inquiry in counseling psychology is timely, and this special issue and subsequent investigations represent welcome areas of scholarship. The observations and comments herein salute the authors for responding to a post-Katrina discovery by…

  17. Insights into Participants' Behaviours in Educational Games, Simulations and Workshops: A Catastrophe Theory Application to Motivation.

    Science.gov (United States)

    Cryer, Patricia

    1988-01-01

    Develops models for participants' behaviors in games, simulations, and workshops based on Catastrophe Theory and Herzberg's two-factor theory of motivation. Examples are given of how these models can be used, both for describing and understanding the behaviors of individuals, and for eliciting insights into why participants behave as they do. (11…

  18. Physical limits of semiconductor laser operation: A time-resolved analysis of catastrophic optical damage

    DEFF Research Database (Denmark)

    Ziegler, Mathias; Hempel, Martin; Larsen, Henning Engelbrecht

    2010-01-01

    The early stages of catastrophic optical damage (COD) in 808 nm emitting diode lasers are mapped by simultaneously monitoring the optical emission with a 1 ns time resolution and deriving the device temperature from thermal images. COD occurs in highly localized damage regions on a 30 to 400 ns...

  19. Catastrophic Failure and Fault-Tolerant Design of IGBT Power Electronic Converters - An Overview

    DEFF Research Database (Denmark)

    Wu, Rui; Blaabjerg, Frede; Wang, Huai;

    2013-01-01

    Reliability is one of the key issues for the application of Insulated Gate Bipolar Transistors (IGBTs) in power electronic converters. Many efforts have been devoted to the reduction of IGBT wear out failure induced by accumulated degradation and catastrophic failure triggered by single-event ove......Reliability is one of the key issues for the application of Insulated Gate Bipolar Transistors (IGBTs) in power electronic converters. Many efforts have been devoted to the reduction of IGBT wear out failure induced by accumulated degradation and catastrophic failure triggered by single......-event overstress. The wear out failure under field operation could be mitigated by scheduled maintenances based on lifetime prediction and condition monitoring. However, the catastrophic failure is difficult to be predicted and thus may lead to serious consequence of power electronic converters. To obtain a better...... understanding of catastrophic failure of IGBTs, the state-of-the-art research on their failure behaviors and failure mechanisms is presented in this paper. Moreover, various fault-tolerant design methods, to prevent converter level malfunctions in the event of IGBT failure, are also reviewed....

  20. Pedagogy in Catastrophic Times: Giroux and the Tasks of Critical Public Intellectuals

    Science.gov (United States)

    Morris, Doug

    2012-01-01

    This article reflects on Henry Giroux's work as a critical public intellectual and the important role his work plays in fostering educated hope and insurgent possibilities during our present times of daily and longer term catastrophes. In addition to attempting to capture the experience of what it means and how it feels to read Giroux along with…

  1. Battleground Energy Recovery Project

    Energy Technology Data Exchange (ETDEWEB)

    Bullock, Daniel [USDOE Gulf Coast Clean Energy Application Center, Woodlands, TX (United States)

    2011-12-31

    In October 2009, the project partners began a 36-month effort to develop an innovative, commercial-scale demonstration project incorporating state-of-the-art waste heat recovery technology at Clean Harbors, Inc., a large hazardous waste incinerator site located in Deer Park, Texas. With financial support provided by the U.S. Department of Energy, the Battleground Energy Recovery Project was launched to advance waste heat recovery solutions into the hazardous waste incineration market, an area that has seen little adoption of heat recovery in the United States. The goal of the project was to accelerate the use of energy-efficient, waste heat recovery technology as an alternative means to produce steam for industrial processes. The project had three main engineering and business objectives: Prove Feasibility of Waste Heat Recovery Technology at a Hazardous Waste Incinerator Complex; Provide Low-cost Steam to a Major Polypropylene Plant Using Waste Heat; and Create a Showcase Waste Heat Recovery Demonstration Project.

  2. Biomechanics of subdural hemorrhage in American football: review of the literature in response to rise in incidence.

    Science.gov (United States)

    Forbes, Jonathan A; Zuckerman, Scott; Abla, Adib A; Mocco, J; Bode, Ken; Eads, Todd

    2014-02-01

    The number of catastrophic head injuries recorded during the 2011 football season was the highest since data collection began in 1984--the vast majority of these cases were secondary to subdural hemorrhage (SDH). The incidence of catastrophic head injury continues to rise: the average yearly incidence from 2008 to 2012 was 238% that of the average yearly incidence from 1998 to 2002. Greater than 95% of the football players who suffered catastrophic head injury during this period were age 18 or younger. Currently, the helmet industry utilizes a standard based on data obtained at Wayne State University approximately 50 years ago that seeks to limit severity index--a surrogate marker of translational acceleration. In this manuscript, we utilize a focused review of the literature to better characterize the biomechanical factors associated with SDH following collisions in American football and discuss these data in the context of current helmet standard. Review of the literature indicates the rotational acceleration (RA) threshold above which the risk of SDH becomes appreciable is approximately 5,000 rad/s(2). This value is not infrequently surmounted in typical high school football games. In contrast, translational accelerations (TAs) experienced during even elite-level impacts in football are not of sufficient magnitude to result in SDH. This information raises important questions about the current helmet standard--in which the sole objective is limitation of TA. Further studies will be necessary to better define whether helmet constructs and quality assurance standards designed to limit RA will also help to decrease the risk of catastrophic head injury in American football.

  3. Optimism Moderates the Influence of Pain Catastrophizing on Shoulder Pain Outcome: A Longitudinal Analysis.

    Science.gov (United States)

    Coronado, Rogelio A; Simon, Corey B; Lentz, Trevor A; Gay, Charles W; Mackie, Lauren N; George, Steven Z

    2017-01-01

    Study Design Secondary analysis of prospectively collected data. Background An abundance of evidence has highlighted the influence of pain catastrophizing and fear avoidance on clinical outcomes. Less is known about the interaction of positive psychological resources with these pain-associated distress factors. Objective To assess whether optimism moderates the influence of pain catastrophizing and fear avoidance on 3-month clinical outcomes in patients with shoulder pain. Methods Data from 63 individuals with shoulder pain (mean ± SD age, 38.8 ± 14.9 years; 30 female) were examined. Demographic, psychological, and clinical characteristics were obtained at baseline. Validated measures were used to assess optimism (Life Orientation Test-Revised), pain catastrophizing (Pain Catastrophizing Scale), fear avoidance (Fear-Avoidance Beliefs Questionnaire physical activity subscale), shoulder pain intensity (Brief Pain Inventory), and shoulder function (Pennsylvania Shoulder Score function subscale). Shoulder pain and function were reassessed at 3 months. Regression models assessed the influence of (1) pain catastrophizing and optimism and (2) fear avoidance and optimism. The final multivariable models controlled for factors of age, sex, education, and baseline scores, and included 3-month pain intensity and function as separate dependent variables. Results Shoulder pain (mean difference, -1.6; 95% confidence interval [CI]: -2.1, -1.2) and function (mean difference, 2.4; 95% CI: 0.3, 4.4) improved over 3 months. In multivariable analyses, there was an interaction between pain catastrophizing and optimism (β = 0.19; 95% CI: 0.02, 0.35) for predicting 3-month shoulder function (F = 16.8, R(2) = 0.69, Pshoulder pain (P = .090) or function (P = .092). Conclusion Optimism decreased the negative influence of pain catastrophizing on shoulder function, but not pain intensity. Optimism did not alter the influence of fear-avoidance beliefs on these outcomes. Level of Evidence

  4. Catastrophic injury in rugby union: is the level of risk acceptable?

    Science.gov (United States)

    Fuller, Colin W

    2008-01-01

    Rugby union is a full contact sport with a relatively high overall risk of injury and a small specific risk of fatal and catastrophic spinal injury. Although catastrophic injuries in rugby union cause public concern and generate strong emotive reactions, the magnitude of society's concern about this type of injury is often dominated by people's perceptions rather than by actual levels of risk. This article assesses published values for the risk of catastrophic injuries in rugby union, evaluates these against the risk standards of the UK Health and Safety Executive (HSE) and compares the values with the risks associated with other common sport and non-sport activities. The assessment showed that the risks of sustaining a catastrophic injury in rugby union in England (0.8/100,000 per year), Ireland (0.9/100,000 per year) and Argentina (1.9/100,000 per year) were within the HSE's 'acceptable' region of risk (0.1-2/100,000 per year), whilst the risks in New Zealand (4.2/100,000 per year), Australia (4.4/100,000 per year) and Fiji (13/100,000 per year) were within the 'tolerable' region of risk (2-100/100,000 per year). The risk of sustaining a catastrophic injury in rugby union was generally lower than or comparable with the levels reported for a wide range of other collision sports, such as ice hockey (4/100,000 per year), rugby league (2/100,000 per year) and American Football (2/100,000 per year). In addition, the risk of catastrophic injury in rugby union was comparable with that experienced by most people in work-based situations and lower than that experienced by motorcyclists, pedestrians and car occupants. Whilst ranking risks provides an effective way of assessing their acceptability, it is recognized that representing risks by a single risk value can be misleading, as account must also be taken of the public's perception of the risks and the inherent differences in the types of risk being considered. However, an acceptable level of risk is often regarded as

  5. Assessment of Flood Catastrophe Risk for Grain Production at the Provincial Scale in China Based on the BMM Method

    Institute of Scientific and Technical Information of China (English)

    XU Lei; ZHANG Qiao; ZHOU Ai-lian; HUO Ran

    2013-01-01

    Flood catastrophe risk assessment is imperative for the steady development of agriculture under the context of global climate change, and meanwhile, it is an urgent scientiifc issue need to be solved in agricultural risk assessment discipline. This paper developed the methodology of lfood catastrophe risk assessment, which can be shown as the standard process of crop loss calculation, Monte Carlo simulation, the generalized extreme value distribution (GEV) iftting, and risk evaluation. Data on crop loss were collected based on hectares covered by natural disasters, hectares affected by natural disasters, and hectares destroyed by natural disasters using the standard equation. Monte Carlo simulation based on appropriate distribution was used to expand sample size to overcome the insufifciency of crop loss data. Block maxima model (BMM) approach based on the extreme value theory was for modeling the generalized extreme value distribution (GEV) of lfood catastrophe loss, and then lfood catastrophe risk at the provincial scale in China was calculated. The Type III Extreme distribution (Weibull) has a weighted advantage of modeling lfood catastrophe risk for grain production. The impact of lfood catastrophe to grain production in China was signiifcantly serious, and high or very high risk of lfood catastrophe mainly concentrates on the central and eastern regions of China. Given the scenario of suffering once-in-a-century lfood disaster, for majority of the major-producing provinces, the probability of 10% reduction of grain output is more than 90%. Especially, the probabilities of more than 15% decline in grain production reach up to 99.99, 99.86, 99.69, and 91.60% respectively in Anhui, Jilin, Liaoning, and Heilongjiang. Flood catastrophe assessment can provide multifaceted information about lfood catastrophe risk that can help to guide management of lfood catastrophe.

  6. The impact of uncertain precipitation data on insurance loss estimates using a Flood Catastrophe Model

    Directory of Open Access Journals (Sweden)

    C. C. Sampson

    2014-01-01

    Full Text Available Catastrophe risk models used by the insurance industry are likely subject to significant uncertainty, but due to their proprietary nature and strict licensing conditions they are not available for experimentation. In addition, even if such experiments were conducted, these would not be repeatable by other researchers because commercial confidentiality issues prevent the details of proprietary catastrophe model structures from being described in public domain documents. However, such experimentation is urgently required to improve decision making in both insurance and re-insurance markets. In this paper we therefore construct our own catastrophe risk model for flooding in Dublin, Ireland in order to assess the impact of typical precipitation data uncertainty on loss predictions. As we consider only a city region rather than a whole territory and have access to detailed data and computing resources typically unavailable to industry modellers, our model is significantly more detailed than commercial products. The model consists of four components, a stochastic rainfall module, a hydrological and hydraulic flood hazard module, a vulnerability module and a financial loss module. Using these we undertake a series of simulations to test the impact of driving the stochastic event generator with four different rainfall data sets: ground gauge data, gauge corrected rainfall radar, meteorological re-analysis data (ERA-Interim and a satellite rainfall product (CMORPH. Catastrophe models are unusual because they use the upper three components of the modelling chain to generate a large synthetic database of unobserved and severe loss-driving events for which estimated losses are calculated. We find these loss estimates to be highly sensitive to uncertainties propagated from the driving observational datasets, suggesting that the range of uncertainty within catastrophe model structures may be greater than commonly believed.

  7. Error and repair catastrophes: A two-dimensional phase diagram in the quasispecies model

    Science.gov (United States)

    Tannenbaum, Emmanuel; Shakhnovich, Eugene I.

    2004-01-01

    This paper develops a two-gene, single fitness peak model for determining the equilibrium distribution of genotypes in a unicellular population which is capable of genetic damage repair. The first gene, denoted by σvia, yields a viable organism with first-order growth rate constant k>1 if it is equal to some target “master” sequence σvia,0. The second gene, denoted by σrep, yields an organism capable of genetic repair if it is equal to some target “master” sequence σrep,0. This model is analytically solvable in the limit of infinite sequence length, and gives an equilibrium distribution which depends on μ≡Lɛ, the product of sequence length and per base pair replication error probability, and ɛr, the probability of repair failure per base pair. The equilibrium distribution is shown to exist in one of the three possible “phases.” In the first phase, the population is localized about the viability and repairing master sequences. As ɛr exceeds the fraction of deleterious mutations, the population undergoes a “repair” catastrophe, in which the equilibrium distribution is still localized about the viability master sequence, but is spread ergodically over the sequence subspace defined by the repair gene. Below the repair catastrophe, the distribution undergoes the error catastrophe when μ exceeds ln k/ɛr, while above the repair catastrophe, the distribution undergoes the error catastrophe when μ exceeds ln k/fdel, where fdel denotes the fraction of deleterious mutations.

  8. Learning from incidents and accidents

    NARCIS (Netherlands)

    Drupsteen, L.; Kampen, J. van

    2014-01-01

    There are many different definitions for what constitutes an incident or an accident, however the focus is always on unintended and often unforeseen events that cause unintended consequences. This article is focused on the process of learning from incidents and accidents. The focus is on making sure

  9. Harnessing Critical Incidents for Learning

    Science.gov (United States)

    Patahuddin, Sitti Maesuri; Lowrie, Tom

    2015-01-01

    A critical incident is a situation or event that holds significance for learning, both for the students and teachers. This paper presents four examples of critical incidents from a Year 7 teacher's lesson excerpts in Indonesia involving teaching of fractions, to show how they shaped classroom situation, brought forward elements of conflict, and…

  10. Chernobyl record. The definitive history of the Chernobyl catastrophe

    Energy Technology Data Exchange (ETDEWEB)

    Mould, R.F

    2000-07-01

    The contents of Chernobyl Record have taken 14 years to compile and this period of time was necessary to enable information to be released from Soviet sources, measurements to be made in the environment, for estimation of radiation doses and for follow-up of the health of population groups which had been exposed. This time frame also includes the 10th anniversary conferences and the completion of joint projects of the European Commission, Ukraine, Belarus and the Russian Federation. It has also enabled me to visit the power plant site, Chernobyl town and Pripyat relatively soon after the accident and also some 10 years later: December 1987 and June 1998. Without such visits some of the photographs in this Record could not have been obtained. Information is also contained in these pages of comparisons of various aspects of the Chernobyl accident with data from the Three Mile Island accident in the USA in 1979, the Hiroshima and Nagasaki atomic bombs, the highly contaminated Techa river area in the Urals in Russia and the accident in Tokaimura, Japan in 1999. The first two chapters are introductory in that they describe terminology which is necessary for an understanding of the remaining chapters. Chapters 3-6 describes the early events: including those leading up to the explosion and then what followed in the immediate aftermath. Chapters 7-8 describe the Sarcophagus and the past and future of nuclear power for electricity generation, including the future of the Chernobyl power station. Chapters 9-11 consider the radiation doses received by various populations, including liquidators, evacuees and those living on contaminated territories: and the contamination of milk by {sup 131}I, and the contamination of other parts of the food chain by {sup 137}Cs. Chapters 12-14 describe the environmental impact of the accident, as does chapter 11. Chapters 15-18 detail the long-term effects on health, including not only the incidence of cancer, but also of non

  11. Beyond enhanced recovery?

    DEFF Research Database (Denmark)

    Jørgensen, Christoffer C; Kehlet, Henrik

    2014-01-01

    We read with great interest the special article by Smart and Daniels discussing several important topics of perioperative care, especially regarding lack of consensus on the definition of "postoperative recovery", and need for further understanding of the pathogenic mechanisms. However, we disagr...... that a "new, clearly defined standard of what "recovery" actually is", demands "a look beyond enhanced recovery"(1) for several reasons. This article is protected by copyright. All rights reserved....

  12. Depressive symptoms and pain evaluations among persons with chronic pain: catastrophizing, but not pain acceptance, shows significant effects.

    Science.gov (United States)

    Richardson, Elizabeth J; Ness, Timothy J; Doleys, Daniel M; Baños, James H; Cianfrini, Leanne; Richards, J Scott

    2009-12-15

    Cognitive factors such as catastrophic thoughts regarding pain, and conversely, one's acceptance of that pain, may affect emotional functioning among persons with chronic pain conditions. The aims of the present study were to examine the effects of both catastrophizing and acceptance on affective ratings of experimentally induced ischemic pain and also self-reports of depressive symptoms. Sixty-seven individuals with chronic back pain completed self-report measures of catastrophizing, acceptance, and depressive symptoms. In addition, participants underwent an ischemic pain induction procedure and were asked to rate the induced pain. Catastrophizing showed significant effects on sensory and intensity but not affective ratings of the induced pain. Acceptance did not show any significant associations, when catastrophizing was also in the model, with any form of ratings of the induced pain. Catastrophizing, but not acceptance, was also significantly associated with self-reported depressive symptoms when these two variables were both included in a regression model. Overall, results indicate negative thought patterns such as catastrophizing appear to be more closely related to outcomes of perceived pain severity and affect in persons with chronic pain exposed to an experimental laboratory pain stimulus than does more positive patterns as reflected in measures of acceptance.

  13. Decreasing incidence rates of bacteremia

    DEFF Research Database (Denmark)

    Nielsen, Stig Lønberg; Pedersen, C; Jensen, T G;

    2014-01-01

    BACKGROUND: Numerous studies have shown that the incidence rate of bacteremia has been increasing over time. However, few studies have distinguished between community-acquired, healthcare-associated and nosocomial bacteremia. METHODS: We conducted a population-based study among adults with first......-acquired, 50.0 for healthcare-associated and 66.7 for nosocomial bacteremia. During 2000-2008, the overall incidence rate decreased by 23.3% from 254.1 to 198.8 (3.3% annually, p ...) and the incidence rate of nosocomial bacteremia decreased by 28.9% from 82.2 to 56.0 (4.2% annually, p

  14. Catastrophic health expenditure: a comparative analysis of empty-nest and non-empty-nest households with seniors in Shandong, China

    Science.gov (United States)

    Yang, Tingting; Chu, Jie; Zhou, Chengchao; Medina, Alexis; Li, Cuicui; Jiang, Shan; Zheng, Wengui; Sun, Liyuan; Liu, Jing

    2016-01-01

    Objective The aim of this study was to compare the catastrophic health expenditure (CHE) prevalence and its determinants between empty-nest and non-empty-nest elderly households. Setting Shandong province of China. Participants A total of 2761 elderly households are included in the analysis. Results CHE incidence among elderly households was 44.9%. The CHE incidence of empty-nest singles (59.3%, p=0.000, OR=3.19) and empty-nest couples (52.9%, p=0.000, OR=2.45) are both statistically higher than that of non-empty-nest elderly households (31.4%). An inverse association was observed between CHE incidence and income level in all elderly household types. Factors including 1 or more household elderly members with non-communicable chronic diseases in the past 6 months, 1 or more elderly household members being hospitalised in the past year and lower household income, are significant risk factors for CHE in all 3 household types (p<0.05). Health insurance status was found to be a significant determinant of CHE among empty-nest singles and non-empty-nest households (p<0.05). Conclusions CHE incidence among elderly households is high in China. Empty-nest households are at higher risk for CHE than non-empty-nest households. Based on these findings, we suggest that special insurance be developed to broaden the coverage of health services and heighten the reimbursement rate for empty-nest elderly in the existing health insurance schemes. Financial and social protection interventions are also essential for identified at-risk subgroups among different types of elderly households. PMID:27381206

  15. Polar catastrophe at the MgO(100)/SnO2(110) interface

    KAUST Repository

    Albar, Arwa

    2016-11-14

    First principles calculations, based on density functional theory, are used to investigate the structural and electronic properties of the epitaxial MgO(100)/SnO2(110) interface of wide band gap insulators. Depending on the interface termination, nonmagnetic metallic and half-metallic interface states are observed. The formation of these states is explained by a polar catastrophe model for nonpolar-polar interfaces. Strong lattice distortions and buckling develop in SnO2, which influence the interface properties as the charge discontinuity is partially screened. Already a single unit cell of SnO2 is sufficient to drive the polar catastrophe scenario. © 2016 The Royal Society of Chemistry.

  16. Scaling law characterizing the dynamics of the transition of HIV-1 to error catastrophe

    Science.gov (United States)

    Gupta, Vipul; Dixit, Narendra M.

    2015-10-01

    Increasing the mutation rate, μ , of viruses above a threshold, {μ }c, has been predicted to trigger a catastrophic loss of viral genetic information and is being explored as a novel intervention strategy. Here, we examine the dynamics of this transition using stochastic simulations mimicking within-host HIV-1 evolution. We find a scaling law governing the characteristic time of the transition: τ ≈ 0.6/≤ft(μ -{μ }c\\right). The law is robust to variations in underlying evolutionary forces and presents guidelines for treatment of HIV-1 infection with mutagens. We estimate that many years of treatment would be required before HIV-1 can suffer an error catastrophe.

  17. Error catastrophe and phase transition in the empirical fitness landscape of HIV

    Science.gov (United States)

    Hart, Gregory R.; Ferguson, Andrew L.

    2015-03-01

    We have translated clinical sequence databases of the p6 HIV protein into an empirical fitness landscape quantifying viral replicative capacity as a function of the amino acid sequence. We show that the viral population resides close to a phase transition in sequence space corresponding to an "error catastrophe" beyond which there is lethal accumulation of mutations. Our model predicts that the phase transition may be induced by drug therapies that elevate the mutation rate, or by forcing mutations at particular amino acids. Applying immune pressure to any combination of killer T-cell targets cannot induce the transition, providing a rationale for why the viral protein can exist close to the error catastrophe without sustaining fatal fitness penalties due to adaptive immunity.

  18. Evaluating core technology capacity based on an improved catastrophe progression method: the case of automotive industry

    Science.gov (United States)

    Zhao, Shijia; Liu, Zongwei; Wang, Yue; Zhao, Fuquan

    2017-01-01

    Subjectivity usually causes large fluctuations in evaluation results. Many scholars attempt to establish new mathematical methods to make evaluation results consistent with actual objective situations. An improved catastrophe progression method (ICPM) is constructed to overcome the defects of the original method. The improved method combines the merits of the principal component analysis' information coherence and the catastrophe progression method's none index weight and has the advantage of highly objective comprehensive evaluation. Through the systematic analysis of the influencing factors of the automotive industry's core technology capacity, the comprehensive evaluation model is established according to the different roles that different indices play in evaluating the overall goal with a hierarchical structure. Moreover, ICPM is developed for evaluating the automotive industry's core technology capacity for the typical seven countries in the world, which demonstrates the effectiveness of the method.

  19. Catastrophe Bonds Structures at European Level – A Cluster Analysis Approach

    Directory of Open Access Journals (Sweden)

    Nadotti Loris Lino Maria

    2014-12-01

    Full Text Available The present paper aims at examining several characteristics of the catastrophe bonds (CB market by focusing on emblematic transactions with the objective of stressing the choices of the European-based (reinsurance groups in terms of the CB tranches structure. For the purpose of highlighting the common individualities regarding the configuration of the catastrophe bonds, there are recognized homogenous groups in terms of covered perils and size of the each CB tranche, while emphasizing some stringent aspects linked to their trigger mechanism (like the basis risk, their rating, or tenor. The research identifies several profiles regarding the structural characteristics of the CB during the entire analysed period (1999-2014 and the main periods of development of the market. Accommodating categorical and continuous data, the structural patterns are determined and analysed by applying the two-step cluster methodology.

  20. Catastrophic model for stability analysis of high pile-column bridge pier

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    According to the engineering features of higher pile-column bridge pier in mountainous area, a clamped beam mechanical model was set up by synthetically analyzing the higher pile-column bridge pier buckling mechanism. Based on the catastrophe theory, the cusp catastrophe model of higher pile-column bridge pier was established by the determination of its potential function and bifurcation set equation, the necessary instability conditions of high pile-column bridge pier were deduced, and the determination method for column-buckling and lateral displacement of high pile-column bridge pier was derived. The comparison between the experimental and calculated results show that the calculated curves agree with testing curves and the method is reasonable and effective.

  1. Changes in Climate Extremes and Catastrophic Events in the Mongolian Plateau from 1951 to 2012

    DEFF Research Database (Denmark)

    Wang, Lei; Yao, Zhi-Jun; Jiang, Liguang;

    2016-01-01

    The spatiotemporal changes in 21 indices of extreme temperature and precipitation for the Mongolian Plateau from 1951 to 2012 were investigated on the basis of daily temperature and precipitation data from 70 meteorological stations. Changes in catastrophic events, such as droughts, floods...... was shown for total precipitation from west to east as based on the spatial distribution of decadal trends. Drought was the most serious extreme disaster, and prolonged drought for longer than 3 yr occurred about every 7-11 yr. An increasing trend in the disaster area was apparent for flood events from 1951......, and snowstorms, were also investigated for the same period. The correlations between catastrophic events and the extreme indices were examined. The results show that the Mongolian Plateau experienced an asymmetric warming trend. Both the cold extremes and warm extremes showed greater warming at night than...

  2. INVESTIGATING FINANCIAL INNOVATION AND EUROPEAN CAPITAL MARKETS. THE CASE OF CATASTROPHE BONDS AND LISTED REINSURANCE COMPANIES

    Directory of Open Access Journals (Sweden)

    CONSTANTIN LAURA-GABRIELA

    2014-12-01

    Full Text Available Focusing on the financial innovation – stock market interconnections, the present research studies the association between the insurance-linked market activity of European (reinsurance companies and their evolution on the capital markets. With the aim of emphasizing the connections from the perspective of the stock performance and their risk, the empirical analysis is based on vector autoregression (VAR and Granger causality analyses. The proposed examination is further developed by considering both impulse response functions and variance decomposition insights. The proxies of the catastrophe bond market, as financial innovation, there are employed both the size and the number of catastrophe bonds transactions, while the stock returns and their standard deviation stand for representatives of the evolution of the reinsurance companies on the capital markets in terms of financial performance and risk. The main results confirm other studies, suggesting that the effects of issuing cat bonds on the ceding companies is reflected rather in terms of stocks’ risk diminishing

  3. INVESTIGATING FINANCIAL INNOVATION AND EUROPEAN CAPITAL MARKETS. THE CASE OF CATASTROPHE BONDS AND LISTED REINSURANCE COMPANIES

    Directory of Open Access Journals (Sweden)

    CONSTANTIN LAURA-GABRIELA

    2014-12-01

    Full Text Available Focusing on the financial innovation – stock market interconnections, the present research studies the association between the insurance-linked market activity of European (reinsurance companies and their evolution on the capital markets. With the aim of emphasizing the connections from the perspective of the stock performance and their risk, the empirical analysis is based on vector autoregression (VAR and Granger causality analyses. The proposed examination is further developed by considering both impulse response functions and variance decomposition insights. The proxies of the catastrophe bond market, as financial innovation, there are employed both the size and the number of catastrophe bonds transactions, while the stock returns and their standard deviation stand for representatives of the evolution of the reinsurance companies on the capital markets in terms of financial performance and risk. The main results confirm other studies, suggesting that the effects of issuing cat bonds on the ceding companies is reflected rather in terms of stocks’ risk diminishing.

  4. "Sizing Up" Codependency Recovery.

    Science.gov (United States)

    Messner, Beth A.

    1996-01-01

    Analyzes codependency related, self-help literature with a dramatistic lens to explore M. Beattie's bibliotherapeutic portrayal of codependency and codependency recovery. Depicts Beattie's "stylistic medicine" for codependency recovery as a three-step, rebirth experience: (1) recognize the codependent pollution within; (2) engage in…

  5. Police Incident Blotter (30 Day)

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — The 30 Day Police Blotter contains the most recent initial crime incident data, updated on a nightly basis. All data is reported at the block/intersection level,...

  6. Idiot Savants: Rate of Incidence

    Science.gov (United States)

    Hill, A. Lewis

    1977-01-01

    A survey of 300 public residential facilities for the mentally retarded revealed a .06 percent incidence rate for idiot savants, persons of low intelligence who possess an unusually high skill in some special task. (CL)

  7. Civil Support: Actions Are Needed to Improve DOD’s Planning for a Complex Catastrophe

    Science.gov (United States)

    2013-09-01

    tsunami, earthquake, volcanic eruption , landslide, mudslide, snowstorm, or drought), or regardless of cause, any fire, flood, or explosion, in any...and emergencies. A major disaster is any natural catastrophe (including any hurricane, tornado, storm, high water , wind-driven water , tidal wave...damage under imminently serious conditions in response to a request from civil authorities when time does not permit approval from higher DOD

  8. Subamolide A Induces Mitotic Catastrophe Accompanied by Apoptosis in Human Lung Cancer Cells

    OpenAIRE

    Jen-Yu Hung; Ching-Wen Wen; Ya-Ling Hsu; En-Shyh Lin; Ming-Shyan Huang; Chung-Yi Chen; Po-Lin Kuo

    2013-01-01

    This study investigated the anticancer effects of subamolide A (Sub-A), isolated from Cinnamomum subavenium, on human nonsmall cell lung cancer cell lines A549 and NCI-H460. Treatment of cancer cells with Sub-A resulted in decreased cell viability of both lung cancer cell lines. Sub-A induced lung cancer cell death by triggering mitotic catastrophe with apoptosis. It triggered oxidant stress, indicated by increased cellular reactive oxygen species (ROS) production and decreased glutathione le...

  9. Risque extensif et risque quotidien dans le Chaco bolivien : sources de crise et catastrophe

    Directory of Open Access Journals (Sweden)

    Lilian R. Reyes Pando

    2012-04-01

    Full Text Available Les risques de catastrophe suivent un continuum qui va des risques structurels initiaux (de pré-impact aux risques futurs ou directement liés aux pratiques de reconstruction et à une récupération1 inadéquate, en passant par les risques contingents (résultant directement de l’impact. Ces différentes catégories sont souvent construites à partir de risques chroniques déjà existants. Elles sont utilisées pour démontrer l’évolution cyclique des catastrophes de 2009 et 2011, associées à la sécheresse et au gel, ayant affectés le Chaco bolivien. Par ailleurs, cet article vise à montrer en quoi une analyse des facteurs de causalité et des impacts post-catastrophe déjà connus est nécessaire. Ces notions sont souvent associées aux aléas à grande échelle pouvant survenir brutalement, mais elles occultent la compréhension des besoins lors de crises qui surviennent à causes d’aléas diffus, extensifs, liés aux styles de vie. Il s’agit également de révéler en quoi les tentatives d’appréhender les catégories successives de risques, apparemment séquencées, en utilisant des mécanismes et des cadres institutionnels indépendants, sont vouées à l’échec. De fait, des relations existent entre risques principaux, risques contingents et risques futurs, et la gestion des risques de catastrophe ainsi que les mécanismes de développement nécessaires pour les réduire.

  10. CATASTROPHIC ABDOMINAL INJURY WITH EVISCERATION OF JEJUNUM AND ILEUM IN A DRAUGHT DONKEY

    Directory of Open Access Journals (Sweden)

    M. H. Hussain, M. Athar, A. Yousaf, G. Muhammad and M. Saqib

    2003-12-01

    Full Text Available The present report describes a catastrophic penetrating abdominal injury associated with a roadside accident in a draught donkey. Though repair of the eviscerated, damaged portion of the small intestine was accomplished successfully, the animal could not be saved. After postmortem it was concluded that hypovolemia and respiratory distress resulted in the death of the wounded donkey before any resuscitating attempt could be made.

  11. Terrestrial catastrophe caused by cometary impact at the end of Cretaceous

    Science.gov (United States)

    Hsü, Kenneth J.

    1980-05-01

    Evidence is presented indicating that the extinction, at the end of the Cretaceous, of large terrestrial animals was caused by atmospheric heating during a cometary impact and that the extinction of calcareous marine plankton was a consequence of poisoning by cyanide released by the fallen comet and of a catastrophic rise in calcite-compensation depth in the oceans after the detoxification of the cyanide.

  12. Catastrophe of coronal magnetic flux ropes in fully open magnetic field

    Institute of Scientific and Technical Information of China (English)

    LI; Guoqiang(李国强); HU; Youqiu(胡友秋)

    2002-01-01

    The catastrophe of coronal magnetic flux ropes is closely related to solar explosive phenomena, such as prominence eruptions, coronal mass ejections, and two-ribbon solar flares. Using a 2-dimensional, 3-component ideal MHD model in Cartesian coordinates, numerical simulations are carried out to investigate the equilibrium property of a coronal magnetic flux rope which is embedded in a fully open background magnetic field. The flux rope emerges from the photosphere and enters the corona with its axial and annular magnetic fluxes controlled by a single "emergence parameter". For a flux rope that has entered the corona, we may change its axial and annular fluxes artificially and let the whole system reach a new equilibrium through numerical simulations. The results obtained show that when the emergence parameter, the axial flux, or the annular flux is smaller than a certain critical value, the flux rope is in equilibrium and adheres to the photosphere. On the other hand, if the critical value is exceeded, the flux rope loses equilibrium and erupts freely upward, namely, a catastrophe takes place. In contrast with the partly-opened background field, the catastrophic amplitude is infinite for the case of fully-opened background field.

  13. Depletion of Paraspeckle Protein 1 Enhances Methyl Methanesulfonate-Induced Apoptosis through Mitotic Catastrophe.

    Directory of Open Access Journals (Sweden)

    Xiangjing Gao

    Full Text Available Previously, we have shown that paraspeckle protein 1 (PSPC1, a protein component of paraspeckles that was involved in cisplatin-induced DNA damage response (DDR, probably functions at the G1/S checkpoint. In the current study, we further examined the role of PSPC1 in another DNA-damaging agent, methyl methanesulfonate (MMS-induced DDR, in particular, focusing on MMS-induced apoptosis in HeLa cells. First, it was found that MMS treatment induced the expression of PSPC1. While MMS treatment alone can induce apoptosis, depletion of PSPC1 expression using siRNA significantly increased the level of apoptosis following MMS exposure. In contrast, overexpressing PSPC1 decreased the number of apoptotic cells. Interestingly, morphological observation revealed that many of the MMS-treated PSPC1-knockdown cells contained two or more nuclei, indicating the occurrence of mitotic catastrophe. Cell cycle analysis further showed that depletion of PSPC1 caused more cells entering the G2/M phase, a prerequisite of mitosis catastrophe. On the other hand, over-expressing PSPC1 led to more cells accumulating in the G1/S phase. Taken together, these observations suggest an important role for PSPC1 in MMS-induced DDR, and in particular, depletion of PSPC1 can enhance MMS-induced apoptosis through mitotic catastrophe.

  14. Induction of mitotic catastrophe by PKC inhibition in Nf1-deficient cells.

    Science.gov (United States)

    Zhou, Xiaodong; Kim, Sung-Hoon; Shen, Ling; Lee, Hyo-Jung; Chen, Changyan

    2014-01-01

    Mutations of tumor suppressor Nf1 gene deregulate Ras-mediated signaling, which confers the predisposition for developing benign or malignant tumors. Inhibition of protein kinase C (PKC) was shown to be in synergy with aberrant Ras for the induction of apoptosis in various types of cancer cells. However, it has not been investigated whether loss of PKC is lethal for Nf1-deficient cells. In this study, using HMG (3-hydroxy-3-methylgutaryl, a PKC inhibitor), we demonstrate that the inhibition of PKC by HMG treatment triggered a persistently mitotic arrest, resulting in the occurrence of mitotic catastrophe in Nf1-deficient ST8814 cells. However, the introduction of the Nf1 effective domain gene into ST8814 cells abolished this mitotic crisis. In addition, HMG injection significantly attenuated the growth of the xenografted ST8814 tumors. Moreover, Chk1 was phosphorylated, accompanied with the persistent increase of cyclin B1 expression in HMG-treated ST8814 cells. The knockdown of Chk1 by the siRNA prevented the Nf1-deficient cells from undergoing HMG-mediated mitotic arrest as well as mitotic catastrophe. Thus, our data suggested that the suppression of PKC activates the Chk1-mediated mitotic exit checkpoint in Nf1-deficient cells, leading to the induction of apoptosis via mitotic catastrophe. Collectively, the study indicates that targeting PKC may be a potential option for developing new strategies to treat Nf1-deficiency-related diseases.

  15. Incorporating Family Function into Chronic Pain Disability: The Role of Catastrophizing

    Directory of Open Access Journals (Sweden)

    Fatemeh Akbari

    2016-01-01

    Full Text Available Background. Observers’ responses to pain are recently investigated to more comprehensively explain chronic pain (CP and disability. However, the role of family context, defined as interference in roles, communication, and problem-solving, and how (i.e., through which mechanisms these variables contribute to CP related disability have yet to be examined. Objectives. The aim of the present study is to examine family context in relationship to pain catastrophizing, fear of movement, and depression and its role in understanding CP disability. Three different models were examined. Methods. A total sample of 142 patients with musculoskeletal chronic pain was recruited to examine the role of fear of movement, pain intensity, pain catastrophizing, and depression in relationship to family functioning as predictors of disability. Results. Findings indicated that two models showed acceptable fit, but one of them revealed superior fit indices. Results of the model with superior fit indices indicated that family dysfunction may contribute to catastrophic thinking, which, in turn, contributes to patients’ disability through increasing fear of movement and depression. Discussion. The current study provides further support for the notion that the impact of emotional and cognitive variables upon CP-related disability can be better understood when we consider the social context of pain patients and family function in particular.

  16. Observational Features of Large-Scale Structures as Revealed by the Catastrophe Model of Solar Eruptions

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Large-scale magnetic structures are the main carrier of major eruptions in the solar atmosphere. These structures are rooted in the photosphere and are driven by the unceasing motion of the photospheric material through a series of equilibrium configurations. The motion brings energy into the coronal magnetic field until the system ceases to be in equilibrium. The catastrophe theory for solar eruptions indicates that loss of mechanical equilibrium constitutes the main trigger mechanism of major eruptions, usually shown up as solar flares,eruptive prominences, and coronal mass ejections (CMEs). Magnetic reconnection which takes place at the very beginning of the eruption as a result of plasma instabilities/turbulence inside the current sheet, converts magnetic energy into heating and kinetic energy that are responsible for solar flares, and for accelerating both plasma ejecta (flows and CMEs) and energetic particles. Various manifestations are thus related to one another, and the physics behind these relationships is catastrophe and magnetic reconnection. This work reports on recent progress in both theoretical research and observations on eruptive phenomena showing the above manifestations. We start by displaying the properties of large-scale structures in the corona and the related magnetic fields prior to an eruption, and show various morphological features of the disrupting magnetic fields. Then, in the framework of the catastrophe theory,we look into the physics behind those features investigated in a succession of previous works,and discuss the approaches they used.

  17. Pain affects spouses too: personal experience with pain and catastrophizing as correlates of spouse distress.

    Science.gov (United States)

    Leonard, Michelle T; Cano, Annmarie

    2006-12-15

    Chronic pain has adverse effects on individuals with chronic pain (ICPs) as well as their family members. Borrowing from an empathy model described by Goubert et al. (2005), we examined top-down and bottom-up factors that may be related to psychological well-being in the spouses of ICPs. A diverse community sample of 113 middle-aged spouses of individuals with chronic pain (ICPs) completed measures on pain severity and spouse pain catastrophizing (PCS-S; Cano et al., 2005). Results showed that almost half (48.7%) of spouses reported chronic pain themselves and that pain in the spouse accounted for within-couple differences on psychological distress. That is, in couples where only the ICP reported pain, ICP psychological distress was greater than their spouses. However, when both partners reported chronic pain, there was no significant difference in psychological distress between partners. Hierarchical regression analyses showed that spouse magnification catastrophizing was associated with depressive and anxiety symptoms, and that helplessness catastrophizing was associated with depressive symptoms for spouses of ICPs who also reported chronic pain but not for spouses of ICPs without chronic pain. The results are discussed in light of interpersonal processes that may affect spouses' distress.

  18. Dynamics of microtubule asters in microfabricated chambers: The role of catastrophes

    Science.gov (United States)

    Faivre-Moskalenko, Cendrine; Dogterom, Marileen

    2002-01-01

    Recent in vivo as well as in vitro experiments have indicated that microtubule pushing alone is sufficient to position a microtubule-organizing center within a cell. Here, we investigate the effect of catastrophes on the dynamics of microtubule asters within microfabricated chambers that mimic the confining geometry of living cells. The use of a glass bead as the microtubule-organizing center allows us to manipulate the aster by using optical tweezers. In the case in which microtubules preexist, we show that because of microtubule buckling, repositioning almost never occurs after relocation with the optical tweezers, although initial microtubule growth always leads the aster to the geometrical center of the chamber. When a catastrophe promoter is added, we find instead that the aster is able to efficiently explore the chamber geometry even after being relocated with the optical tweezers. As predicted by theoretical calculations, the results of our in vitro experiments clearly demonstrate the need for catastrophes for proper positioning in a confining geometry. These findings correlate with recent observations of nuclear positioning in fission yeast cells. PMID:12486218

  19. Pain catastrophizing predicts pain intensity during a neurodynamic test for the median nerve in healthy participants.

    Science.gov (United States)

    Beneciuk, Jason M; Bishop, Mark D; George, Steven Z

    2010-08-01

    Psychological factors within the Fear-Avoidance Model of Musculoskeletal Pain (FAM) predict clinical and experimental pain in both symptomatic and asymptomatic individuals. Clinicians routinely examine individuals with provocative testing procedures that evoke symptoms. The purpose of this study was to investigate which FAM factors were associated with evoked pain intensity, non-painful symptom intensity, and range of motion during an upper-limb neurodynamic test. Healthy participants (n = 62) completed psychological questionnaires for pain catastrophizing, fear of pain, kinesiophobia, and anxiety prior to neurodynamic testing. Pain intensity, non-painful sensation intensity, and elbow range of motion (ROM) were collected during testing and served as dependent variables in separate simultaneous regression models. All the psychological predictors in the model accounted for 18% of the variance in evoked pain intensity (p = .02), with only pain catastrophizing (beta = .442, p neurodynamic testing for healthy subjects. Although these findings cannot be directly translated to clinical practice, the influence of pain catastrophizing on evoked pain responses should be considered during neurodynamic testing.

  20. Overfishing reduces resilience of kelp beds to climate-driven catastrophic phase shift.

    Science.gov (United States)

    Ling, S D; Johnson, C R; Frusher, S D; Ridgway, K R

    2009-12-29

    A key consideration in assessing impacts of climate change is the possibility of synergistic effects with other human-induced stressors. In the ocean realm, climate change and overfishing pose two of the greatest challenges to the structure and functioning of marine ecosystems. In eastern Tasmania, temperate coastal waters are warming at approximately four times the global ocean warming average, representing the fastest rate of warming in the Southern Hemisphere. This has driven range extension of the ecologically important long-spined sea urchin (Centrostephanus rodgersii), which has now commenced catastrophic overgrazing of productive Tasmanian kelp beds leading to loss of biodiversity and important rocky reef ecosystem services. Coincident with the overgrazing is heavy fishing of reef-based predators including the spiny lobster Jasus edwardsii. By conducting experiments inside and outside Marine Protected Areas we show that fishing, by removing large predatory lobsters, has reduced the resilience of kelp beds against the climate-driven threat of the sea urchin and thus increased risk of catastrophic shift to widespread sea urchin barrens. This shows that interactions between multiple human-induced stressors can exacerbate nonlinear responses of ecosystems to climate change and limit the adaptive capacity of these systems. Management actions focused on reducing the risk of catastrophic phase shift in ecosystems are particularly urgent in the face of ongoing warming and unprecedented levels of predator removal from the world's oceans.

  1. Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes.

    Science.gov (United States)

    Doodhi, Harinath; Prota, Andrea E; Rodríguez-García, Ruddi; Xiao, Hui; Custar, Daniel W; Bargsten, Katja; Katrukha, Eugene A; Hilbert, Manuel; Hua, Shasha; Jiang, Kai; Grigoriev, Ilya; Yang, Chia-Ping H; Cox, David; Horwitz, Susan Band; Kapitein, Lukas C; Akhmanova, Anna; Steinmetz, Michel O

    2016-07-11

    Microtubules are dynamic polymers built of tubulin dimers that attach in a head-to-tail fashion to form protofilaments, which further associate laterally to form a tube. Asynchronous elongation of individual protofilaments can potentially lead to an altered microtubule-end structure that promotes sudden depolymerization, termed catastrophe [1-4]. However, how the dynamics of individual protofilaments relates to overall growth persistence has remained unclear. Here, we used the microtubule targeting anti-cancer drug Eribulin [5-7] to explore the consequences of stalled protofilament elongation on microtubule growth. Using X-ray crystallography, we first revealed that Eribulin binds to a site on β-tubulin that is required for protofilament plus-end elongation. Based on the structural information, we engineered a fluorescent Eribulin molecule. We demonstrate that single Eribulin molecules specifically interact with microtubule plus ends and are sufficient to either trigger a catastrophe or induce slow and erratic microtubule growth in the presence of EB3. Interestingly, we found that Eribulin increases the frequency of EB3 comet "splitting," transient events where a slow and erratically progressing comet is followed by a faster comet. This observation possibly reflects the "healing" of a microtubule lattice. Because EB3 comet splitting was also observed in control microtubules in the absence of any drugs, we propose that Eribulin amplifies a natural pathway toward catastrophe by promoting the arrest of protofilament elongation.

  2. Cyber Incidents Involving Control Systems

    Energy Technology Data Exchange (ETDEWEB)

    Robert J. Turk

    2005-10-01

    The Analysis Function of the US-CERT Control Systems Security Center (CSSC) at the Idaho National Laboratory (INL) has prepared this report to document cyber security incidents for use by the CSSC. The description and analysis of incidents reported herein support three CSSC tasks: establishing a business case; increasing security awareness and private and corporate participation related to enhanced cyber security of control systems; and providing informational material to support model development and prioritize activities for CSSC. The stated mission of CSSC is to reduce vulnerability of critical infrastructure to cyber attack on control systems. As stated in the Incident Management Tool Requirements (August 2005) ''Vulnerability reduction is promoted by risk analysis that tracks actual risk, emphasizes high risk, determines risk reduction as a function of countermeasures, tracks increase of risk due to external influence, and measures success of the vulnerability reduction program''. Process control and Supervisory Control and Data Acquisition (SCADA) systems, with their reliance on proprietary networks and hardware, have long been considered immune to the network attacks that have wreaked so much havoc on corporate information systems. New research indicates this confidence is misplaced--the move to open standards such as Ethernet, Transmission Control Protocol/Internet Protocol, and Web technologies is allowing hackers to take advantage of the control industry's unawareness. Much of the available information about cyber incidents represents a characterization as opposed to an analysis of events. The lack of good analyses reflects an overall weakness in reporting requirements as well as the fact that to date there have been very few serious cyber attacks on control systems. Most companies prefer not to share cyber attack incident data because of potential financial repercussions. Uniform reporting requirements will do much to make this

  3. One day at a time: The impact of daily satisfaction with spouse responses on pain, negative affect and catastrophizing among individuals with rheumatoid arthritis.

    Science.gov (United States)

    Holtzman, Susan; Delongis, Anita

    2007-09-01

    The majority of research on pain catastrophizing has focused on its negative consequences for adjustment to chronic pain, with few investigations of factors that influence catastrophizing or its detrimental effects. Using a daily process methodology, the current study examined, first, the extent to which a supportive social environment plays a role in reduced catastrophizing, and second, the extent to which support might protect against the detrimental effects of catastrophizing on well-being. Sixty-nine married individuals with rheumatoid arthritis took part in an initial background interview, followed by twice daily telephone interviews (regarding pain intensity, negative affect, catastrophizing and satisfaction with spouse responses) for 1 week. Multi-level modeling indicated several pathways through which satisfaction with spouse responses disrupts the vicious cycle of pain, negative affect and catastrophizing. Consistent with past research, catastrophizing was associated with increases in pain and negative affect. However, when individuals reported increases in satisfaction with spouse responses they were less likely to experience increases in negative affect due to catastrophizing. Satisfaction with spouse responses also reduced the likelihood of feeling overwhelmed and helpless in dealing with daily pain. The relationship between pain and catastrophizing was attenuated in the context of increases in satisfaction with spouse responses. Negative affect was associated with increases in catastrophizing, but only when individuals reported decreases in satisfaction with spouse responses. Overall, findings were consistent with a model in which satisfaction with spouse responses serves as a coping resource, and suggests the importance of involving close others in treatments to reduce pain and catastrophizing.

  4. GLACIER DEGRADATION AND CATASTROPHIC MUDFLOWS ORIGIN FROM THE MODERN GLACIAL-MORAINE BODIES IN THE ELBRUS REGION

    Directory of Open Access Journals (Sweden)

    E. A. Zolotarev

    2012-01-01

    Full Text Available Mechanism of formation of the catastrophic mudflows in different glacial valleys of Elbrus region at the present stage of glacial degradation is described. The important role of the buried ice in the formation of catastrophic mudflows that affected Tyrnyauz in the XX century was revealed as a result of remote monitoring of changes in glacial-moraine complex of Kayarta river. The dynamics of glacial lakes in the Adyl-Su valley in the Bashkara Glacier region was described and probability of their breakthrough was estimated. The quantitative indicators of the dynamics of the landslide in the Kubasanty valley were obtained as a result of remote monitoring, and its influence on the formation of catastrophic mudflows is discovered. Various possible methods of catastrophic mudflows prevention not requiring expensive protective constructions are discussed.

  5. Virtual reality exposure therapy as treatment for pain catastrophizing in fibromyalgia patients: proof-of-concept study (Study Protocol

    Directory of Open Access Journals (Sweden)

    Spottiswoode Bruce

    2011-04-01

    Full Text Available Abstract Background Albeit exercise is currently advocated as one of the most effective management strategies for fibromyalgia syndrome (FMS; the implementation of exercise as a FMS treatment in reality is significantly hampered by patients' poor compliance. The inference that pain catastrophizing is a key predictor of poor compliance in FMS patients, justifies considering the alteration of pain catastrophizing in improving compliance towards exercises in FMS patients. The aim of this study is to provide proof-of-concept for the development and testing of a novel virtual reality exposure therapy (VRET program as treatment for exercise-related pain catastrophizing in FMS patients. Methods Two interlinked experimental studies will be conducted. Study 1 aims to objectively ascertain if neurophysiological changes occur in the functional brain areas associated with pain catastrophizing, when catastrophizing FMS subjects are exposed to visuals of exercise activities. Study 2 aims to ascertain the preliminary efficacy and feasibility of exposure to visuals of exercise activities as a treatment for exercise-related pain catastrophizing in FMS subjects. Twenty subjects will be selected from a group of FMS patients attending the Tygerberg Hospital in Cape Town, South Africa and randomly allocated to either the VRET (intervention group or waiting list (control group. Baseline neurophysiological activity for subjects will be collected in study 1 using functional magnetic resonance imaging (fMRI. In study 2, clinical improvement in pain catastrophizing will be measured using fMRI (objective and the pain catastrophizing scale (subjective. Discussion The premise is if exposing FMS patients to visuals of various exercise activities trigger the functional brain areas associated with pain catastrophizing; then as a treatment, repeated exposure to visuals of the exercise activities using a VRET program could possibly decrease exercise-related pain catastrophizing

  6. Delayed cell death associated with mitotic catastrophe in γ-irradiated stem-like glioma cells

    Directory of Open Access Journals (Sweden)

    Esser Norbert

    2011-06-01

    Full Text Available Abstract Background and Purpose Stem-like tumor cells are regarded as highly resistant to ionizing radiation (IR. Previous studies have focused on apoptosis early after irradiation, and the apoptosis resistance observed has been attributed to reduced DNA damage or enhanced DNA repair compared to non-stem tumor cells. Here, early and late radioresponse of patient-derived stem-like glioma cells (SLGCs and differentiated cells directly derived from them were examined for cell death mode and the influence of stem cell-specific growth factors. Materials and methods Primary SLGCs were propagated in serum-free medium with the stem-cell mitogens epidermal growth factor (EGF and fibroblast growth factor-2 (FGF-2. Differentiation was induced by serum-containing medium without EGF and FGF. Radiation sensitivity was evaluated by assessing proliferation, clonogenic survival, apoptosis, and mitotic catastrophe. DNA damage-associated γH2AX as well as p53 and p21 expression were determined by Western blots. Results SLGCs failed to apoptose in the first 4 days after irradiation even at high single doses up to 10 Gy, but we observed substantial cell death later than 4 days postirradiation in 3 of 6 SLGC lines treated with 5 or 10 Gy. This delayed cell death was observed in 3 of the 4 SLGC lines with nonfunctional p53, was associated with mitotic catastrophe and occurred via apoptosis. The early apoptosis resistance of the SLGCs was associated with lower γH2AX compared to differentiated cells, but we found that the stem-cell culture cytokines EGF plus FGF-2 strongly reduce γH2AX levels. Nonetheless, in two p53-deficient SLGC lines examined γIR-induced apoptosis even correlated with EGF/FGF-induced proliferation and mitotic catastrophe. In a line containing CD133-positive and -negative stem-like cells, the CD133-positive cells proliferated faster and underwent more γIR-induced mitotic catastrophe. Conclusions Our results suggest the importance of delayed

  7. The role of catastrophic geomorphic events in central Appalachian landscape evolution

    Science.gov (United States)

    Jacobson, R.B.; Miller, A.J.; Smith, J.A.

    1989-01-01

    Catastrophic geomorphic events are taken as those that are large, sudden, and rare on human timescales. In the nonglaciated, low-seismicity central Appalachians, these are dominantly floods and landslides. Evaluation of the role of catastrophic events in landscape evolution includes assessment of their contributions to denudation and formation of prominent landscape features, and how they vary through space and time. Tropical storm paths and topographic barriers at the Blue Ridge and Allegheny Front create significant climatic variability across the Appalachians. For moderate floods, the influence of basin geology is apparent in modifying severity of flooding, but for the most extreme events, flood discharges relate mainly to rainfall characteristics such as intensity, duration, storm size, and location. Landslide susceptibility relates more directly to geologic controls that determine what intensity and duration of rainfall will trigger slope instability. Large floods and landslides are not necessarily effective in producing prominent geomorphic features. Large historic floods in the Piedmont have been minimally effective in producing prominent and persistent geomorphic features. In contrast, smaller floods in the Valley and Ridge produced erosional and depositional features that probably will require thousands of years to efface. Scars and deposits of debris slide-avalanches triggered on sandstone ridges recover slowly and persist much longer than scars and deposits of smaller landslides triggered on finer-grained regolith, even though the smaller landslides may have eroded greater aggregate volume. The surficial stratigraphic record can be used to extend the spatial and temporal limits of our knowledge of catastrophic events. Many prominent alluvial and colluvial landforms in the central Appalachians are composed of sediments that were deposited by processes similar to those observed in historic catastrophic events. Available stratigraphic evidence shows two

  8. A population-based, incidence cohort study of mid-back pain after traffic collisions

    DEFF Research Database (Denmark)

    Johansson, M S; Boyle, E; Hartvigsen, Jan;

    2015-01-01

    BACKGROUND: Traffic collisions often result in a wide range of symptoms included in the umbrella term whiplash-associated disorders. Mid-back pain (MBP) is one of these symptoms. The incidence and prognosis of different traffic injuries and their related conditions (e.g. neck pain, low back pain......, depression or others) has been investigated previously; however, knowledge about traffic collision-related MBP is lacking. The study objectives were to describe the incidence, course of recovery and prognosis of MBP after traffic collisions, in terms of global self-reported recovery. METHODS: Longitudinal...... recovery was 101 days (95% CI: 99-104) and about 23% were still not recovered after 1 year. Participant's expectation for recovery, general health, extent of severely affecting comorbidities and having experienced a previous traffic injury were some of the prognostic factors identified. CONCLUSIONS...

  9. Virtual reality exposure therapy as treatment for pain catastrophizing in fibromyalgia patients: proof-of-concept study (Study Protocol)

    OpenAIRE

    Spottiswoode Bruce; Grimmer-Somers Karen A; Morris Linzette D; Louw Quinette A

    2011-01-01

    Abstract Background Albeit exercise is currently advocated as one of the most effective management strategies for fibromyalgia syndrome (FMS); the implementation of exercise as a FMS treatment in reality is significantly hampered by patients' poor compliance. The inference that pain catastrophizing is a key predictor of poor compliance in FMS patients, justifies considering the alteration of pain catastrophizing in improving compliance towards exercises in FMS patients. The aim of this study ...

  10. Role of pain catastrophizing during pain processing in a cohort of patients with chronic and severe arthritic knee pain.

    Science.gov (United States)

    Wade, James B; Riddle, Daniel L; Price, Donald D; Dumenci, Levent

    2011-02-01

    We examined the relationship between catastrophizing and a 3-stage model of pain processing, consisting of pain sensation intensity (stage 1), pain unpleasantness (stage 2), and suffering (stage 3). We studied 310 patients with chronic and severe osteoarthritic knee pain (68.7% female) using 4 competing structural equation models. A strong relationship was found between the suffering construct and its indicators. Of the 4 theoretically plausible models, we found a model with 3 specific pathways of pain sensation leading to the final stage of pain-related suffering. A unique contribution of this study is the integration of catastrophizing into the 3 pain stages. In this model, catastrophizing mediates the relationship between pain-related unpleasantness and suffering, as well as the relationship between sensation and suffering through unpleasantness. Psychological intervention targeting catastrophizing could provide reduction of pain-related suffering that adds to the benefits of therapies directed toward the primary sensory and immediate unpleasant dimensions of pain. These results emphasize the benefit of integrating knowledge of the psychological and neural mechanisms of pain. Catastrophizing makes a unique contribution to suffering apart from the contribution of immediate unpleasantness. The study results emphasize the benefit of integrating knowledge of the psychological and neural mechanisms of pain, and the importance of psychological intervention targeting catastrophizing to reduce pain-related suffering.

  11. Catastrophic Inflation

    CERN Document Server

    Downes, Sean; Sinha, Kuver

    2011-01-01

    We study inflection point inflation using Singularity Theory, which relates degenerate critical points of functions to their local behavior. This approach illuminates universal features of small-field models and gives analytic control over parametrized families of scalar potentials near inflationary solutions. The behavior of the scalar potential is tied to the number of physical input parameters, which determines a set of universality classes. Within these classes, we obtain universal scaling relations for density perturbations and the scale of inflation. In specific models, we show that the scale of supersymmetry breaking also possesses scaling behavior. We illustrate this general structure with a specific example: the Racetrack Inflation model in type IIB string theory, with the inflaton being the real part of the K\\"ahler modulus, and the input parameters being flux dependent quantities that appear in the 4D, N=1 superpotential.

  12. A Bumpy Recovery

    Institute of Scientific and Technical Information of China (English)

    CHEN FENGYING

    2010-01-01

    @@ The world economic situation has been extremely complicated in 2010. This year saw fluctuating market confidence,changing commodity prices, imbalanced economic recovery, diverse economic policies, lingering trade protectionism, and fierce currency battles.

  13. Recovery Audit Program

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Recovery Audit Programs mission is to identify and correct Medicare improper payments through the efficient detection and collection of overpayments made on...

  14. Disaster Debris Recovery Database

    Data.gov (United States)

    U.S. Environmental Protection Agency — The US EPA Region 5 Disaster Debris Recovery Database includes public datasets of over 3,500 composting facilities, demolition contractors, haulers, transfer...

  15. Silver recovery system data

    Energy Technology Data Exchange (ETDEWEB)

    Boulineau, B.

    1991-08-26

    In August of 1990 the Savannah River Site Photography Group began testing on a different type of silver recovery system. This paper describes the baseline study and the different phases of installation and testing of the system.

  16. Enhanced oil recovery

    Energy Technology Data Exchange (ETDEWEB)

    Chakma, A.; Rafiq Islam, M.; Berruti, F.

    1991-01-01

    Some forty to sixty percent of the original oil in place typically remains trapped in the reservoir after primary and secondary recoveries. Enhanced oil recovery refers to the recovery of the residual oil by different techniques. Many of the existing and proposed enhanced oil recovery techniques require sound understanding of basic chemical engineering principles such as fluid flow, heat and mass transfer, interfacial phenomena etc. Chemical EOR techniques require a good understanding of interfacial phenomena, chemical reaction, multicomponent absorption. Understanding of the fundamentals of the various EOR processes is not adequate. EOR is increasingly attracting a growing number of chemical engineers and, as a result, some of the fundamental aspect of EOR are now being investigated. However, much more remains to be done and chemical engineers can play an important role in providing a better understanding of EOR fundamentals. This volume presents selected papers on EOR presented at AICHE meetings.

  17. Recovery Action Mapping Tool

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Recovery Action Mapping Tool is a web map that allows users to visually interact with and query actions that were developed to recover species listed under the...

  18. FEMA Disaster Recovery Centers

    Data.gov (United States)

    Department of Homeland Security — This is a search site for FEMA's Disaster Recovery Centers (DRC). A DRC is a readily accessible facility or mobile office set up by FEMA where applicants may go for...

  19. Cardiovascular disease incidence and survival

    DEFF Research Database (Denmark)

    Byberg, Stine; Agyemang, Charles; Zwisler, Ann Dorthe

    2016-01-01

    Studies on cardiovascular disease (CVD) incidence and survival show varying results between different ethnic groups. Our aim was to add a new dimension by exploring the role of migrant status in combination with ethnic background on incidence of-and survival from-CVD and more specifically acute...... significantly lower incidence of CVD, AMI and stroke. All-cause and cause-specific survival after CVD, AMI and stroke was similar or significantly better for migrants compared to Danish-born, regardless of type of migrant (refugee vs. family-reunified) or country of origin. Refugees are disadvantaged in terms...... of some types of cardiovascular disease compared to Danish-born. Family-reunified migrants on the other hand had lower rates of CVD. All migrants had better survival than Danish-born indicating that migrants may not always be disadvantaged in health....

  20. Evaluating the potential for catastrophic fault-rupture-related hazards affecting a key hydroelectric and irrigation region in central Asia

    Science.gov (United States)

    Rust, D.; Korjenkov, A.; Tibaldi, A.; Usmanova, M.

    2009-04-01

    of these toxic dumps are vulnerable to seismically induced landsliding, release of reservoir water and breaching of very large (up to several km3) landslide-dammed lakes within the deep mountain valleys typical of the fault zone. The May 2008 earthquake in neighboring Sichuan, in which some 30 landslide-dammed lakes were created, may be useful in refining hazard scenarios developed from the multi-pronged analysis employed in our study. This analysis involves compiling all relevant existing data, such as seismic archives held in paper format, within the project GIS. Spatial and temporal patterns exhibited by these compiled data, together with focal mechanism determinations where possible, are combined with data on the distribution and nature of geological units to provide estimates of peak ground acceleration and the likely incidence of seismically-triggered slope instability. This compilation also identifies data deficiencies to be targeted using a portable seismometer network, geophysical and geodetic surveys, InSAR and other remote sensing data; all combined with geotechnical and palaeoseismological fieldwork. Initial results from this approach confirm the ground-shaking potential of Talas-Fergana rupture events, suggest a long-term slip rate as high as 15 mm a-1, and the occurrence of the last ground-rupturing event some 4-500 years BP. The lack of significant activity since that event suggests the Talas-Fergana structure may comprise a seismic gap within the Tien-Shan, highlighting the importance of hazard scenarios in proposing mitigation measures against potentially catastrophic threats, such as extensive pollution of irrigated lands in the Fergana Valley downstream from Toktogul on which some 10 million people depend.

  1. Recovery of an isolated coral reef system following severe disturbance.

    Science.gov (United States)

    Gilmour, James P; Smith, Luke D; Heyward, Andrew J; Baird, Andrew H; Pratchett, Morgan S

    2013-04-05

    Coral reef recovery from major disturbance is hypothesized to depend on the arrival of propagules from nearby undisturbed reefs. Therefore, reefs isolated by distance or current patterns are thought to be highly vulnerable to catastrophic disturbance. We found that on an isolated reef system in north Western Australia, coral cover increased from 9% to 44% within 12 years of a coral bleaching event, despite a 94% reduction in larval supply for 6 years after the bleaching. The initial increase in coral cover was the result of high rates of growth and survival of remnant colonies, followed by a rapid increase in juvenile recruitment as colonies matured. We show that isolated reefs can recover from major disturbance, and that the benefits of their isolation from chronic anthropogenic pressures can outweigh the costs of limited connectivity.

  2. S. pombe kinesins-8 promote both nucleation and catastrophe of microtubules.

    Directory of Open Access Journals (Sweden)

    Muriel Erent

    Full Text Available The kinesins-8 were originally thought to be microtubule depolymerases, but are now emerging as more versatile catalysts of microtubule dynamics. We show here that S. pombe Klp5-436 and Klp6-440 are non-processive plus-end-directed motors whose in vitro velocities on S. pombe microtubules at 7 and 23 nm s(-1 are too slow to keep pace with the growing tips of dynamic interphase microtubules in living S. pombe. In vitro, Klp5 and 6 dimers exhibit a hitherto-undescribed combination of strong enhancement of microtubule nucleation with no effect on growth rate or catastrophe frequency. By contrast in vivo, both Klp5 and Klp6 promote microtubule catastrophe at cell ends whilst Klp6 also increases the number of interphase microtubule arrays (IMAs. Our data support a model in which Klp5/6 bind tightly to free tubulin heterodimers, strongly promoting the nucleation of new microtubules, and then continue to land as a tubulin-motor complex on the tips of growing microtubules, with the motors then dissociating after a few seconds residence on the lattice. In vivo, we predict that only at cell ends, when growing microtubule tips become lodged and their growth slows down, will Klp5/6 motor activity succeed in tracking growing microtubule tips. This mechanism would allow Klp5/6 to detect the arrival of microtubule tips at cells ends and to amplify the intrinsic tendency for microtubules to catastrophise in compression at cell ends. Our evidence identifies Klp5 and 6 as spatial regulators of microtubule dynamics that enhance both microtubule nucleation at the cell centre and microtubule catastrophe at the cell ends.

  3. Mechanism for the catastrophe-promoting activity of the microtubule destabilizer Op18/stathmin.

    Science.gov (United States)

    Gupta, Kamlesh K; Li, Chunlei; Duan, Aranda; Alberico, Emily O; Kim, Oleg V; Alber, Mark S; Goodson, Holly V

    2013-12-17

    Regulation of microtubule dynamic instability is crucial for cellular processes, ranging from mitosis to membrane transport. Stathmin (also known as oncoprotein 18/Op18) is a prominent microtubule destabilizer that acts preferentially on microtubule minus ends. Stathmin has been studied intensively because of its association with multiple types of cancer, but its mechanism of action remains controversial. Two models have been proposed. One model is that stathmin promotes microtubule catastrophe indirectly, and does so by sequestering tubulin; the other holds that stathmin alters microtubule dynamics by directly destabilizing growing microtubules. Stathmin's sequestration activity is well established, but the mechanism of any direct action is mysterious because stathmin binds to microtubules very weakly. To address these issues, we have studied interactions between stathmin and varied tubulin polymers. We show that stathmin binds tightly to Dolastatin-10 tubulin rings, which mimic curved tubulin protofilaments, and that stathmin depolymerizes stabilized protofilament-rich polymers. These observations lead us to propose that stathmin promotes catastrophe by binding to and acting upon protofilaments exposed at the tips of growing microtubules. Moreover, we suggest that stathmin's minus-end preference results from interactions between stathmin's N terminus and the surface of α-tubulin that is exposed only at the minus end. Using computational modeling of microtubule dynamics, we show that these mechanisms could account for stathmin's observed activities in vitro, but that both the direct and sequestering activities are likely to be relevant in a cellular context. Taken together, our results suggest that stathmin can promote catastrophe by direct action on protofilament structure and interactions.

  4. Phase diagram of the two-fluid Lipkin model: A "butterfly" catastrophe

    Science.gov (United States)

    García-Ramos, J. E.; Pérez-Fernández, P.; Arias, J. M.; Freire, E.

    2016-03-01

    Background: In the past few decades quantum phase transitions have been of great interest in nuclear physics. In this context, two-fluid algebraic models are ideal systems to study how the concept of quantum phase transition evolves when moving into more complex systems, but the number of publications along this line has been scarce up to now. Purpose: We intend to determine the phase diagram of a two-fluid Lipkin model that resembles the nuclear proton-neutron interacting boson model Hamiltonian using both numerical results and analytic tools, i.e., catastrophe theory, and compare the mean-field results with exact diagonalizations for large systems. Method: The mean-field energy surface of a consistent-Q -like two-fluid Lipkin Hamiltonian is studied and compared with exact results coming from a direct diagonalization. The mean-field results are analyzed using the framework of catastrophe theory. Results: The phase diagram of the model is obtained and the order of the different phase-transition lines and surfaces is determined using a catastrophe theory analysis. Conclusions: There are two first-order surfaces in the phase diagram, one separating the spherical and the deformed shapes, while the other separates two different deformed phases. A second-order line, where the later surfaces merge, is found. This line finishes in a transition point with a divergence in the second-order derivative of the energy that corresponds to a tricritical point in the language of the Ginzburg-Landau theory for phase transitions.

  5. Overcoming catastrophic interference in connectionist networks using Gram-Schmidt orthogonalization.

    Directory of Open Access Journals (Sweden)

    Vipin Srivastava

    Full Text Available Connectionist models of memory storage have been studied for many years, and aim to provide insight into potential mechanisms of memory storage by the brain. A problem faced by these systems is that as the number of items to be stored increases across a finite set of neurons/synapses, the cumulative changes in synaptic weight eventually lead to a sudden and dramatic loss of the stored information (catastrophic interference, CI as the previous changes in synaptic weight are effectively lost. This effect does not occur in the brain, where information loss is gradual. Various attempts have been made to overcome the effects of CI, but these generally use schemes that impose restrictions on the system or its inputs rather than allowing the system to intrinsically cope with increasing storage demands. We show here that catastrophic interference occurs as a result of interference among patterns that lead to catastrophic effects when the number of patterns stored exceeds a critical limit. However, when Gram-Schmidt orthogonalization is combined with the Hebb-Hopfield model, the model attains the ability to eliminate CI. This approach differs from previous orthogonalisation schemes used in connectionist networks which essentially reflect sparse coding of the input. Here CI is avoided in a network of a fixed size without setting limits on the rate or number of patterns encoded, and without separating encoding and retrieval, thus offering the advantage of allowing associations between incoming and stored patterns. PACS Nos.: 87.10.+e, 87.18.Bb, 87.18.Sn, 87.19.La.

  6. The relationship of adult attachment dimensions to pain-related fear, hypervigilance, and catastrophizing.

    Science.gov (United States)

    McWilliams, Lachlan A; Asmundson, Gordon J G

    2007-01-01

    Despite the prominence of fear-avoidance models of chronic pain, there is a paucity of research regarding the origins of pain-related fear. Based on the premise that insecure attachment could be a developmentally based origin of elevated fear of pain, associations between adult attachment dimensions and constructs included in fear-avoidance models of chronic pain were investigated. Consistent with Bartholomew and Horowitz's [Bartholomew K, Horowitz LM. Attachment styles among young adults: a test of a four-category model. J Pers Soc Psychol 1991;61:226-44.] model, attachment was conceptualized as being comprised of a model of self dimension (i.e., degree of anxiety regarding rejection based on beliefs of personal unworthiness) and a model of others dimension (i.e., degree of interpersonal mistrust and discomfort with interpersonal closeness). A large university student sample free of chronic pain (N=278) completed a measure of adult romantic attachment (i.e., Experiences in Close Relationships Questionnaire; [Brennan KA, Clark CL, Shaver PR. Self-report measurement of adult attachment: an integrative overview. In: Simpson JA, Rholes WS, editors. Attachment theory and close relationships. New York: The Guilford Press, 1998. p. 46-76.]), the Fear of Pain Questionnaire-III [McNeil DW, Rainwater AJ. Development of the fear of pain questionnaire - III. J Behav Med 1998;21:389-410.], the Pain Vigilance and Awareness Questionnaire [McCracken LM. Attention to pain in persons with chronic pain: a behavioural approach. Behav Ther 1997;28:271-84.], and the Pain Catastrophizing Scale [Sullivan MJ, Bishop SR, Pivik J. The pain catastrophizing scale: development and validation. Psychol Assess 1995;7:24-532.]. It was hypothesized that insecure attachment would be positively associated with reports of pain-related fear, hypervigilance, and catastrophizing and that the model of self dimension would be the attachment variable most strongly associated with these variables

  7. Lupus anticoagulant-hypoprothrombinemia syndrome and catastrophic antiphospholipid syndrome in a patient with antidomain I antibodies.

    Science.gov (United States)

    Galland, Joris; Mohamed, Shirine; Revuz, Sabine; de Maistre, Emmanuel; de Laat, Bas; Marie, Pierre-Yves; Zuily, Stéphane; Lévy, Bruno; Regnault, Véronique; Wahl, Denis

    2016-07-01

    Lupus anticoagulant-hypoprothrombinemia syndrome is a rare condition characterized by the association of acquired factor II deficiency and lupus anticoagulant. Contrary to classical antiphospholipid syndrome, it may cause severe life-threatening bleeding (89% of published cases). We report a patient, positive for antidomain I antibodies, with initially primary lupus anticoagulant-hypoprothrombinemia syndrome without previous clinical manifestation or underlying systemic disease. Five years later, he experienced the first systemic lupus erythematous flare. Within a few days, catastrophic antiphospholipid syndrome was diagnosed with heart, liver and kidney involvement. The patient recovered under pulse steroids, intravenous heparin and intravenous immunoglobulins.

  8. Catastrophic antiphospholipid syndrome and pulmonary embolism in a 3-year-old child

    Energy Technology Data Exchange (ETDEWEB)

    Olivier, Carine; Blondiaux, Eleonore; Dacher, Jean-Nicolas [University Hospital of Rouen, Department of Radiology, Rouen (France); Blanc, Thierry [University Hospital of Rouen, Department of Neonatal Medicine, Rouen (France); Borg, Jeanne-Yvonne [University Hospital of Rouen, Haematology Laboratory, Rouen (France)

    2006-08-15

    We report a rare example of catastrophic antiphospholipid syndrome (CAPS) in a young child. A 3-year-old girl with no previous medical history presented with extensive and recurrent thromboses. The diagnosis of CAPS was based on the occurrence of cardiopulmonary embolism in the child with a high titre of autoantibodies directed against phospholipids and beta-2-glycoprotein 1. In spite of a relatively rapid diagnosis and multiple treatments, the outcome was unfavourable. Multimodality imaging, including both ultrasonography and spiral CT, allowed close follow-up of the thromboses. (orig.)

  9. Reactive oxygen species regulate a balance between mitotic catastrophe and apoptosis.

    Science.gov (United States)

    Sorokina, Irina V; Denisenko, Tatiana V; Imreh, Gabriela; Gogvadze, Vladimir; Zhivotovsky, Boris

    2016-12-01

    Mitotic catastrophe (MC) is a sequence of events resulting from premature or inappropriate entry of cells into mitosis that can be caused by chemical or physical stresses. There are several observations permitting to define MC as an oncosuppressive mechanism. MC can end up in apoptosis, necrosis or senescence. Here we show that the anticancer drug doxorubicin triggers DNA damage and MC independently of ROS production. In contrast, doxorubicin-induced apoptosis was found to be ROS-dependent. Antioxidants NAC or Trolox suppressed apoptosis, but facilitated MC development. Our data demonstrate that evasion of apoptosis and subsequent stimulation of MC can contribute to tumor cell elimination improving anticancer therapy.

  10. A double-ended queue with catastrophes and repairs, and a jump-diffusion approximation

    CERN Document Server

    Di Crescenzo, Antonio; Kumar, Balasubramanian Krishna; Nobile, Amelia G; 10.1007/s11009-011-9214-2

    2011-01-01

    Consider a system performing a continuous-time random walk on the integers, subject to catastrophes occurring at constant rate, and followed by exponentially-distributed repair times. After any repair the system starts anew from state zero. We study both the transient and steady-state probability laws of the stochastic process that describes the state of the system. We then derive a heavy-traffic approximation to the model that yields a jump-diffusion process. The latter is equivalent to a Wiener process subject to randomly occurring jumps, whose probability law is obtained. The goodness of the approximation is finally discussed.

  11. Hydrogen Civilization Doctrine: Whether the Humankind Can Prevent Global Ecological Catastrophe?

    Institute of Scientific and Technical Information of China (English)

    GOLTSOV V. A.; GOLTSOVA L. F.; SPORTSMEN L. A.; GOLTSOVA M. V.

    2012-01-01

    Hydrogen Civilization (HyCi) doctrine is a novel world outlook,all-embracing vision of the sustainability of the human future:humanity can preclude world climate catastrophe and conserve the biosphere's ability to maintain the life of humanity by the only way,just by the sustainable movement along the vector "Hydrogen Energy → Hydrogen Economy → Hydrogen Civilization".HyCi doctrine is overcoming boundaries between different sciences,between peoples and nations.Hydrogen civilization is a public ideal (‘superattractor’)putting in the forefront Shakespeare's Hamlet question on a global scale:"To be or not to be the humankind:that is the question".

  12. Pain affects spouses too: Personal experience with pain and catastrophizing as correlates of spouse distress ⋆

    OpenAIRE

    2006-01-01

    Chronic pain has adverse effects on individuals with chronic pain (ICPs) as well as their family members. Borrowing from an empathy model described by Goubert et al. (2005), we examined top-down and bottom-up factors that may be related to psychological well-being in the spouses of ICPs. A diverse community sample of 113 middle-aged spouses of individuals with chronic pain (ICPs) completed measures on pain severity and spouse pain catastrophizing (PCS-S; Cano et al., 2005). Results showed tha...

  13. Successes and failures of compulsory risk mitigation: re-evaluating the Turkish Catastrophe Insurance Pool.

    Science.gov (United States)

    Başbuğ-Erkan, B Burcak; Yilmaz, Ozlem

    2015-10-01

    The Turkish Catastrophe Insurance Pool (TCIP) is one of the best practices of public-private partnerships in an emerging market designed to reduce economic losses from disasters. This paper reviews the application of this compulsory mechanism along with data relating to the performance of the scheme following recent earthquakes in Turkey. We also consider the current perceptions of Turkish society towards the TCIP and how they can be enhanced. Our conclusions aim to assist stakeholders in government, homeowners, insurance companies, media, banks and civil society to appreciate the value of the system and key actions necessary to improve it.

  14. CHINA HEALTH INSURANCE%Identification of Families at Catastrophic Medical Risk

    Institute of Scientific and Technical Information of China (English)

    褚福灵

    2016-01-01

    Study on methods for the identifi cation of families at catastrophic medical risk is needed to prevent poverty caused by illness and to realize precise poverty alleviation. Catastrophic medical risk families refer to families with catastrophic medical (Health) expenditures, which are families with large amount of medical expenses or poor families caused by illness. From the dimensions of medical expenses, diseases in family members, family income, family property, physical and mental health status of family members and so on, the catastrophic medical risk families are divided into 1-4 level (from low to high). When compensating for medical cost, it should submit to high risk family to prevent poverty caused by illness.%研究灾难性医疗风险家庭的认定办法,是防范因病致贫风险和实现精准扶贫的需要。灾难性医疗风险家庭是指发生了灾难性医疗(卫生)支出的家庭,分为大额医疗费用家庭与因病致贫家庭。从“医疗费用、家庭成员患病情况、家庭收入、家庭财产、家庭成员体能与心智状况”等维度,将灾难性医疗风险家庭分为1-4个级别。1级灾难性医疗风险最低,4级灾难性医疗风险最高。在对医疗费用补偿时,应当向灾难性医疗支出风险大的家庭倾斜,以确保困难家庭及弱势群体的灾难性医疗风险得到化解,防范因病致贫现象发生。

  15. Changes in Climate Extremes and Catastrophic Events in the Mongolian Plateau from 1951 to 2012

    DEFF Research Database (Denmark)

    Wang, Lei; Yao, Zhi-Jun; Jiang, Liguang;

    2016-01-01

    The spatiotemporal changes in 21 indices of extreme temperature and precipitation for the Mongolian Plateau from 1951 to 2012 were investigated on the basis of daily temperature and precipitation data from 70 meteorological stations. Changes in catastrophic events, such as droughts, floods...... in the daytime. The spatial changes in significant trends showed a good homogeneity and consistency in Inner Mongolia. Changes in the precipitation extremes were not as obvious as those in the temperature extremes. The spatial distributions in changes of precipitation extremes were complex. Adecreasing trend...

  16. Ecological recovery in ERA

    DEFF Research Database (Denmark)

    EFSA Scientific Committee (Scientific Committee); Topping, Christopher John

    2016-01-01

    EFSA performs environmental risk assessments (ERAs) for single potential stressors such as plant protection products, genetically modified organisms and feed additives and for invasive alien species that are harmful for plant health. In this risk assessment domain, the EFSA Scientific Committee...... recognises the importance of more integrated ERAs considering both the local and landscape scales, as well as the possible co-occurrence of multiple potential stressors that fall under the remit of EFSA, which are important when addressing ecological recovery. In this scientific opinion, the Scientific...... Committee gathered scientific knowledge on the potential for the recovery of non-target organisms for the further development of ERA. Current EFSA guidance documents and opinions were reviewed on how ecological recovery is addressed in ERA schemes. In addition, this scientific opinion is based on expert...

  17. The Impact of Universal Coverage Policy on Catastrophic Health Payments in Thailand%泰国全民覆盖政策对灾难性卫生支出的影响

    Institute of Scientific and Technical Information of China (English)

    高倩; 任苒

    2013-01-01

    Before 2002, the three existing basic medical security systems of Thailand covered 30% of the population, and the surplus population participated in the universal coverage(UC)policy of medical security system which promulgated in 2002. Since the implement of UC policy, it has improved the equity of medical service application and health financing, reduced Catastrophic Health Payments and low-income groups have obtained more benefits. The incidence rate of Catastrophic Health Payments decreased and the spending burden of catastrophic health expenditure in low-income groups decreased from 6.11%(2000)to 4.65%(2002).%2002年以前,泰国3个原有的基本医疗保障制度覆盖了30%的人口,2002年颁布的全民覆盖(UC)政策覆盖了剩余人口,使泰国实现了医疗保障的全民覆盖。全民覆盖改革实施后,改善了医疗服务利用和卫生筹资的公平性,减少了灾难性卫生支出,尤其是低收入组受益较大。灾难性卫生支出的发生率有所降低,其中低收入组人群家庭灾难性卫生支出负担从2000年的6.11%降低到2002年的4.65%。

  18. Spatially Dispersed Employee Recovery

    DEFF Research Database (Denmark)

    Hvass, Kristian Anders; Torfadóttir, Embla

    2014-01-01

    , who have a work place away from a fixed or central location and have minimal management contact. Results suggest that the support employees receive from management, such as recognition, information sharing, training, and strategic awareness are all important for spatially dispersed front......-line employees' satisfaction with management's actions and overall employee recovery.......Employee recovery addresses either employee well-being or management's practices in aiding employees in recovering themselves following a service failure. This paper surveys the cabin crew at a small, European, low-cost carrier and investigates employees' perceptions of management practices to aid...

  19. Epigenetics in Stroke Recovery

    Science.gov (United States)

    Kassis, Haifa; Shehadah, Amjad; Chopp, Michael; Zhang, Zheng Gang

    2017-01-01

    Abstract: While the death rate from stroke has continually decreased due to interventions in the hyperacute stage of the disease, long-term disability and institutionalization have become common sequelae in the aftermath of stroke. Therefore, identification of new molecular pathways that could be targeted to improve neurological recovery among survivors of stroke is crucial. Epigenetic mechanisms such as post-translational modifications of histone proteins and microRNAs have recently emerged as key regulators of the enhanced plasticity observed during repair processes after stroke. In this review, we highlight the recent advancements in the evolving field of epigenetics in stroke recovery. PMID:28264471

  20. Orimulsion containment and recovery

    Energy Technology Data Exchange (ETDEWEB)

    Sommerville, M. [Briggs Marine Environmental Services, Aberdeen (United Kingdom)

    1999-01-01

    This paper focuses on the need for examination of Orimulsion fuel and its spill behaviour in the light of the anticipated increase in consumption of this fuel which comprises bitumen dispersed in water with addition of a small amount of surfactant. The behaviour and fate of Orimulsion at sea, and observations from experimental and sea trials are examined. The identification of spill control techniques, spill detection, the predictive modeling of the spill and response, sub-surface plume measurement, and containment and deflection are considered. Recovery of the bitumen produced from an Orimulsion spill, combined containment and recovery, dispersed Orimulsion, and beach cleaning are addressed. The properties of Orimulsion are tabulated. (UK)

  1. Recovery in aluminium

    DEFF Research Database (Denmark)

    Gundlach, Carsten

    2006-01-01

    In the present thesis the development of a unique experimental method for volume characterisation of individual embedded crystallites down to a radius of 150 nm is presented. This method is applied to in-situ studies of recovery in aluminium. The method is an extension of 3DXRD microscopy, an X...... are represented as strings. To identify the strings a combination of a 5D connected component type algorithm and multi-peak fitting was found to be superior. The first use of the method was a study of recovery of a deformed aluminium alloy (AA1050). The aluminium alloy was deformed by cold rolling to a thickness...

  2. Breakout and Tether-cutting Eruption Models Are Both Catastrophic (Sometimes)

    CERN Document Server

    Longcope, D W

    2013-01-01

    We present a simplified analytic model of a quadrupolar magnetic field and flux rope to model coronal mass ejections. The model magnetic field is two-dimensional, force-free and has current only on the axis of the flux rope and within two currents sheets. It is a generalization of previous models containing a single current sheet anchored to a bipolar flux distribution. Our new model can undergo quasi-static evolution due either to changes at the boundary or to magnetic reconnection at either current sheet. We find that all three kinds of evolution can lead to a catastrophe known as loss of equilibrium. Some equilibria can be driven to catastrophic instability either through reconnection at the lower current sheet, known as tether cutting, or through reconnection at the upper current sheet, known as breakout. Other equilibria can be destabilized through only one and not the other. Still others undergo no instability, but evolve increasingly rapidly in response to slow steady driving (ideal or reconnective). O...

  3. Catastrophic drought in East Asian monsoon region during Heinrich event 1

    Science.gov (United States)

    Zhou, Xin; Sun, Liguang; Chu, Yangxi; Xia, Zehui; Zhou, Xinying; Li, Xiangzhong; Chu, Zhuding; Liu, Xiangjun; Shao, Da; Wang, Yuhong

    2016-06-01

    Heinrich event 1 (H1) is an important millennial climate event during the last deglaciation. The substantial decreasing of monsoon strength in the East Asian monsoon region during the H1, as shown by stalagmite δ18O records, has been attributed to the southward shift of the intertropical convergence zone (ITCZ), which is caused by the slowdown/collapse of the Atlantic meridional overturning circulation (AMOC). However, records from different Asian monsoon regions show various trends in precipitation changes during the H1, and these trends cannot be solely interpreted by the southward shift of the ITCZ. In the present study, we reconstructed time-series of East Asian monsoon precipitation between 25,000 and 10,000 a BP from floodplain sediments in the Huai River Basin. A white sediment layer, distinct from other layers in the profile, contains significantly low TOC, tree pollen and fern spore contents, and more positive δ13Corg, and it is deposited during the H1 event. The determined TOC, pollen and δ13Corg time-series, together with previously reported stalagmite δ18O, indicate a catastrophic (severe) drought in Jianghuai Region, one of the East Asian monsoon regions, during the H1. The La Niña condition in tropical Pacific likely also contributes to the catastrophic drought in Jianghuai Region and the precipitation variations in the Asian monsoon region during the H1.

  4. Catastrophes in non-equilibrium many-particle wave functions: universality and critical scaling

    Science.gov (United States)

    Mumford, J.; Kirkby, W.; O’Dell, D. H. J.

    2017-02-01

    As part of the quest to uncover universal features of quantum dynamics, we study catastrophes that form in simple many-particle wave functions following a quench, focusing on two-mode systems that include the two-site Bose–Hubbard model, and under some circumstances optomechanical systems and the Dicke model. When the wave function is plotted in Fock space certain characteristic shapes, that we identify as cusp catastrophes, appear under generic conditions. In the vicinity of a cusp the wave function takes on a universal structure described by the Pearcey function and obeys scaling relations which depend on the total number of particles N. In the thermodynamic limit (N\\to ∞ ) the cusp becomes singular, but at finite N it is decorated by an interference pattern. This pattern contains an intricate network of vortex–antivortex pairs, initiating a theory of topological structures in Fock space. In the case where the quench is a δ-kick the problem can be solved analytically and we obtain scaling exponents for the size and position of the cusp, as well as those for the amplitude and characteristic length scales of its interference pattern. Finally, we use these scalings to describe the wave function in the critical regime of a {{{Z}}}2 symmetry-breaking dynamical phase transition.

  5. Phase diagram of the two-fluid Lipkin model: a butterfly catastrophe

    CERN Document Server

    García-Ramos, J E; Arias, J M; Freire, E

    2016-01-01

    Background: In the last few decades quantum phase transitions have been of great interest in Nuclear Physics. In this context, two-fluid algebraic models are ideal systems to study how the concept of quantum phase transition evolves when moving into more complex systems, but the number of publications along this line has been scarce up to now. Purpose: We intend to determine the phase diagram of a two-fluid Lipkin model, that resembles the nuclear proton-neutron interacting boson model Hamiltonian, using both numerical results and analytic tools, i.e., catastrophe theory, and to compare the mean-field results with exact diagonalizations for large systems. Method: The mean-field energy surface of a consistent-Q-like two-fluid Lipkin Hamiltonian is studied and compared with exact results coming from a direct diagonalization. The mean-field results are analyzed using the framework of catastrophe theory. Results: The phase diagram of the model is obtained and the order of the different phase-transition lines and ...

  6. Exponential Orthogonality Catastrophe in Single-Particle and Many-Body Localized Systems

    Science.gov (United States)

    Deng, Dong-Ling; Pixley, J. H.; Li, Xiaopeng

    We investigate the statistical orthogonality catastrophe (StOC) in single-particle and many-body localized systems by studying the response of the many-body ground state to a local quench. Using scaling arguments and exact numerical calculations, we establish that the StOC gives rise to a wave function overlap between the pre- and post-quench ground states that has an exponential decay with the system size, in sharp contrast to the well-known power law Anderson orthogonality catastrophe in metallic systems. This exponential decay arises from a statistical charge transfer process where a particle can be effectively ``transported'' to an arbitrary lattice site. We show that in a many-body localized phase, this non-local transport and the associated exponential StOC phenomenon persist in the presence of interactions. We study the possible experimental consequences of the exponential StOC on the Loschmidt echo and spectral function, establishing that this phenomenon might be observable in cold atomic experiments through Ramsey interference and radio-frequency spectroscopy. We thank S.-T. Wang, Z.-X. Gong, Y.-L. Wu, J. D. Sau, and Z. Ovadyahu for discussions. This work is supported by LPS-MPO-CMTC, JQI-NSF-PFC, and ARO-Atomtronics-MURI. The authors acknowledge the University of Maryland supercomputing resources.

  7. Conditions of Agricultural Catastrophe Risks in China and Establishment of Agricultural Risks Protection Systems

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Agricultural risks in our country have been introduced:firstly,disasters are multiple and frequently happened;secondly,widely affected and seriously suffered.Features of risks also are introduced:the first is the agricultural risk unit is large;the second is the agricultural risk is strongly regional;the third is the agricultural risk is universally half revival.The paper discusses the limits of the agricultural risks management,pointing out that in the management systems of agricultural risks,government finance is strongly burdened,compensations on the catastrophe is small in region,low in level.Based on the above analysis,the protection systems of agricultural risks have been constructed:the first is to establish the reassurance systems of agricultural risks;the second is to establish the risk funds of single agricultural item;the third is to transfer the catastrophe risks through stocks;the fourth is to construct multi leveled countermeasures of agricultural risks.

  8. On the obstacles and way to assess the seismic catastrophe for high arch dams

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    To prevent possible seismic catastrophe,naturally,its assessment is deeply concerned over in China as a series of arch dams of about 300 m high will be constructed in the severe seismic regions.In this paper the major obstacles to the seismic catastrophe assessment of high arch dams which focused on clearly defining the Maximum Credible Earthquake (MCE) and reasonably selecting its site-specific seismic input parameters as well as quantitatively evaluating the limit state of dam-breach for designers are emphasized.Some breakthrough progress with pending problems is presented,such as to adopt more reasonable seismic input parameters based on seismic hazard evaluation of dam site; to develop model and method more fit in with the reality for non-linear seismic analysis of dam-foundation-reservoir system.The ideals of further improvement both in evaluating the MCE and defining the quantitative index of its performance objective are discussed,including how to use semi-empirical method of simulating strong ground motion near fault,how to solve the long-standing problem of stress singularity at dam heel,and how to investigate dynamic behaviors of fully-graded damconcrete through dynamic tests and 3-dimensional meso-mechanics analysis checked by CT technique.

  9. CSL protein regulates transcription of genes required to prevent catastrophic mitosis in fission yeast.

    Science.gov (United States)

    Převorovský, Martin; Oravcová, Martina; Zach, Róbert; Jordáková, Anna; Bähler, Jürg; Půta, František; Folk, Petr

    2016-11-16

    For every eukaryotic cell to grow and divide, intricately coordinated action of numerous proteins is required to ensure proper cell-cycle progression. The fission yeast Schizosaccharomyces pombe has been instrumental in elucidating the fundamental principles of cell-cycle control. Mutations in S. pombe 'cut' (cell untimely torn) genes cause failed coordination between cell and nuclear division, resulting in catastrophic mitosis. Deletion of cbf11, a fission yeast CSL transcription factor gene, triggers a 'cut' phenotype, but the precise role of Cbf11 in promoting mitotic fidelity is not known. We report that Cbf11 directly activates the transcription of the acetyl-coenzyme A carboxylase gene cut6, and the biotin uptake/biosynthesis genes vht1 and bio2, with the former 2 implicated in mitotic fidelity. Cbf11 binds to a canonical, metazoan-like CSL response element (GTGGGAA) in the cut6 promoter. Expression of Cbf11 target genes shows apparent oscillations during the cell cycle using temperature-sensitive cdc25-22 and cdc10-M17 block-release experiments, but not with other synchronization methods. The penetrance of catastrophic mitosis in cbf11 and cut6 mutants is nutrient-dependent. We also show that drastic decrease in biotin availability arrests cell proliferation but does not cause mitotic defects. Taken together, our results raise the possibility that CSL proteins play conserved roles in regulating cell-cycle progression, and they could guide experiments into mitotic CSL functions in mammals.

  10. Sri Lanka : de la lutte contre le terrorisme à la catastrophe humanitaire

    Directory of Open Access Journals (Sweden)

    Delon Madavan

    2009-04-01

    Full Text Available La volonté du gouvernement sri lankais d’en finir militairement avec le LTTE a abouti à une catastrophe humanitaire. L’armée et les Tigres se rendent coupables de crime de guerre et de crime contre l’humanité à l’encontre des civils tamouls, qui sont piégés dans la zone de combat ou enfermés dans des camps de détention. La perception différenciée de l’opération militaire selon les communautés nécessiterait la création d’un Tribunal Pénal International pour Sri Lanka.The will of Sri Lankan government to finish militarily with LTTE has ended with an humanitarian catastrophe. Both the Sri Lankan Army and the Tigers are guilty of international war and humanitarian crimes against Tamil civilians, who are trapped in the war zone or locked in detention camps. The different perceptions of the military operation according to the communities should need the creation of an International Penal Court for Sri Lanka

  11. Catastrophic glacial multi-phase mass movements: a special type of glacial hazard

    Directory of Open Access Journals (Sweden)

    D. A. Petrakov

    2008-04-01

    Full Text Available Many glacier-related hazards are well typified and studied, but some events stand out from conventional classifications. The Kolka-Karmadon catastrophic event on 20 September 2002 in North Ossetia, North Caucasus, Russia is used as an example of a complex glacier failure exhibiting characteristics such as high mobility, long runout, ultrarapid movement and multiphase behaviour. We consider terminology protocol for glacier hazard classification and then, using the Kolka-Karmadon event and several other examples from around the world, we propose a new term for this family of events. Catastrophic glacier multi-phase mass movement (CGMM is described and further illustrated by eight major events from Russia, Georgia, Peru, Chile, and Canada. CGMM have a combination of specific features: extraordinary velocities and long-distance runout despite low path angle; progressive fluidisation along travel path; superelevation and run-up of the moving mass, air blast wave in the avalanche flow phase; entrainment of available materials in its path, and the repeated nature of the event. CGMM events may affect areas remote from glaciers which were previously considered as safe.

  12. State Methods for a Cyber Incident

    Science.gov (United States)

    2012-03-01

    Statewide Emergency Response and Response Plan SIPC State Infrastructure Protection Center SIRT Security Incident Response Team SIRT State Incident...by statute and policy to report agency information security incidents to the state Security Incident Response Team ( SIRT ). Those reports are made...through recent state statutes. P-16 Yes, agencies are required by statute and policy to report information security incidents to the SIRT . Q-17

  13. Good Gradings of Generalized Incidence Rings

    CERN Document Server

    Price, Kenneth L

    2011-01-01

    This inquiry is based on both the construction of generalized incidence rings due to Gene Abrams and the construction of good group gradings of incidence algebras due to Molli Jones. We provide conditions for a generalized incidence ring to be graded isomorphic to a subring of an incidence ring over a preorder. We also extend Jones's construction to good group gradings for incidence algebras over preorders with crosscuts of length one or two.

  14. Critical incident. An ethical dilemma.

    Science.gov (United States)

    County, B

    2000-10-01

    The purpose of this critical incident analysis is to demonstrate how knowledge of legal, moral and ethical issues has affected my nursing practice. This is a personal journey--an exploration of my own values and beliefs. The piece demonstrates how reviewing the literature has changed my stance on the issues discussed. Consequently, the piece is written in the first person, but references are used to substantiate my findings.

  15. A One Year Prospective Study of Neurogenic Stuttering Following Stroke: Incidence and Co-Occurring Disorders

    Science.gov (United States)

    Theys, C.; van Wieringen, A.; Sunaert, S.; Thijs, V.; De Nil, L. F.

    2011-01-01

    In this prospective study, data on incidence, stuttering characteristics, co-occurring speech disorders, and recovery of neurogenic stuttering in a large sample of stroke participants were assessed. Following stroke onset, 17 of 319 participants (5.3%; 95% CI, 3.2-8.3) met the criteria for neurogenic stuttering. Stuttering persisted in at least…

  16. Cancer incidence in pulmonary vasculitis.

    Science.gov (United States)

    Zycinska, Katarzyna; Kostrzewa-Janicka, Jolanta; Nitsch-Osuch, Aneta; Wardyn, Kazimierz

    2013-01-01

    Pulmonary vasculitis is a potentially lethal autoimmune disease characterized by granulomatous inflammation of respiratory tract, necrotizing vasculitis affecting small-to medium-size vessels and antineutrophil cytoplasmic antibodies elevation. Typical therapy involves high-dose glucocorticosteroids combined with cyclophosphamide in a dose 1-2 mg/kg/per day. A high relapse rate in pulmonary vasculitis means prolonged courses of cyclophosphamide in some patients. Carcinogenic effects of cyclophosphamide, especially its toxic metabolite acrolein that is excreted into the urine, are responsible for the development of acute myeloid leukemia (AML) and bladder cancer. These and other malignancies are cyclophosphamide dose-depended. The aim of the present study was to assess the incidence of cancer in patients with pulmonary vasculitis in comparison with the incidence of cancer in the general population. Analyses were done according to the cumulative dose of cyclophosphamide, subdivided into low (≤35 g) and high (>35 g). During the observation period 15 cancers occurred. A significantly increased standardized incidence ratio (SIR) was observed for non-melanoma skin cancers (SIR 5.2; 95 % Cl 2.3-8.7), AML (SIR 4.3; 95 % Cl 2.1-11.2), and bladder cancer (SIR 3.4; 95 % Cl 1.6-5.2). Induction remission treatment and relapse treatment with cyclophosphamide involves a substantial risk of late appearing malignances in patients with pulmonary vasculitis. Monitoring and prophylactic management in pulmonary vasculitis after cessation of cyclophosphamide therapy is crucial.

  17. Cost Recovery Through Depreciation.

    Science.gov (United States)

    Forrester, Robert T.; Wesolowski, Leonard V.

    1983-01-01

    The approach of adopting depreciation rather than use allowance in order to recover more accurately the cost of college buildings and equipment used on federal projects is considered. It is suggested that depreciation will offer most colleges and universities a higher annual recovery rate, and an opportunity for better facilities planning. For…

  18. The Ghanaian Economic Recovery

    Science.gov (United States)

    2013-12-01

    struggle for power between the Bretton Woods institutions and African leaders.28 20 Nii K. Sowa...Oriented Industrial Output in Ghana: The Case of Formal Wood Processing in an Era of Economic Recovery.” The Journal of Modern African Studies 39

  19. Sulfur recovery further improved

    Energy Technology Data Exchange (ETDEWEB)

    Borsboom, J.; Grinsven, M. van; Warners, A. van [Jacobs Nederland B.V., (Netherlands); Nisselrooy, P. van [Gastec N.V., (Netherlands)

    2002-04-01

    The original 100-year-old Claus process for producing sulfur from hydrogen sulfide in acid gas is described together with improvements which have been made over the years. The most recent modification, EUROCLAUS, achieves sulfur recoveries of 99-99.9 per cent. Five commercial units are being designed.

  20. Recovery of Interdependent Networks

    CERN Document Server

    Di Muro, M A; Stanley, H E; Havlin, S; Braunstein, L A

    2015-01-01

    Recent network research has focused on the cascading failures in a system of interdependent networks and the necessary preconditions for system collapse. An important question that has not been addressed is how to repair a failing system before it suffers total breakdown. Here we introduce a recovery strategy of nodes and develop an analytic and numerical framework for studying the concurrent failure and recovery of a system of interdependent networks based on an efficient and practically reasonable strategy. Our strategy consists of repairing a fraction of failed nodes, with probability of recovery $\\gamma$, that are neighbors of the largest connected component of each constituent network. We find that, for a given initial failure of a fraction $1-p$ of nodes, there is a critical probability of recovery above which the cascade is halted and the system fully restores to its initial state and below which the system abruptly collapses. As a consequence we find in the plane $\\gamma-p$ of the phase diagram three ...

  1. A Bumpy Recovery

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The world economy crawls ahead amid risk and uncertainty The world economic situation has been extremely complicated in 2010. This year saw fluctuating market confidence,changing commodity prices, imbalanced economic recovery, diverse economic policies, lingering trade protectionism, and fierce currency battles.

  2. Recovery in the East

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    As robust as the economic recovery in East Asia has been in recent months,attention must now be turned to managing emerging risks challenging macroeconomic stability,said World Bank’s latest East Asia and Pacific Economic Update released on October 19.Edited excerpts follow

  3. Health service use, out-of-pocket payments and catastrophic health expenditure among older people in India

    DEFF Research Database (Denmark)

    Brinda, Ethel Mary; Kowal, Paul; Attermann, Jørn;

    2015-01-01

    BACKGROUND: Healthcare financing through out-of-pocket payments and inequities in healthcare utilisation are common in low and middle income countries (LMICs). Given the dearth of pertinent studies on these issues among older people in LMICs, we investigated the determinants of health service use......, out-of-pocket and catastrophic health expenditures among older people in one LMIC, India. METHODS: We accessed data from a nationally representative, multistage sample of 2414 people aged 65 years and older from the WHO's Study on global Ageing and adult health in India. Sociodemographic...... the number of health visits and out-of-pocket health expenditures. The prevalence of catastrophic health expenditure among older people in India was 7% (95% CI 6% to 8%). Older men and individuals with chronic diseases were at higher risk of catastrophic health expenditure, while access to health insurance...

  4. La catastrophe nucléaire de Tchernobyl entre erreurs humaines et défauts techniques

    CERN Document Server

    Perrineau, Aude

    2015-01-01

    Découvrez enfin tout ce qu'il faut savoir sur la catastrophe nucléaire de Tchernobyl en moins d'une heure ! Le 26 avril 1986 à 1 h 23, une catastrophe d'un nouveau genre ébranle le monde : un réacteur de la centrale nucléaire de Tchernobyl explose. Alors que les autorités soviétiques camouflent l'accident, puis en minimisent l'importance, un nuage radioactif se forme et se propage sur toute l'Europe…Ce livre vous permettra d'en savoir plus sur : Le contexte de l'époque Les acteurs majeurs qui ont participé à l'événement La catastrophe nucléaire de Tchernobyl Les répercussions du drameLe mot

  5. Associations between Neuroticism and Depression in Relation to Catastrophizing and Pain-Related Anxiety in Chronic Pain Patients.

    Science.gov (United States)

    Kadimpati, Sandeep; Zale, Emily L; Hooten, Michael W; Ditre, Joseph W; Warner, David O

    2015-01-01

    Several cognitive-affective constructs, including pain catastrophizing and pain-related anxiety, have been implicated in the onset and progression of chronic pain, and both constructs have been identified as key targets for multidisciplinary pain treatment. Both neuroticism and depression have been linked to these constructs (and to each other), but how each may contribute to the pain experience is unknown. This study tested associations between neuroticism, depression, and indices of catastrophizing and pain-related anxiety among persons seeking treatment for chronic non-malignant pain. We hypothesized, as a higher-order personality trait, neuroticism would remain uniquely associated with both pain catastrophizing and pain-related anxiety, even after accounting for current symptoms of depression. A retrospective study design assessed depression (as measured by the Centers for Epidemiologic Studies-Depression scale), neuroticism (measured with the Neuroticism-Extraversion-Openness Personality Inventory), the Pain Catastrophizing Scale, and the Pain Anxiety Symptom Score in a consecutive series of patients (n=595) admitted to a 3-week outpatient pain treatment program from March 2009 through January 2011. Hierarchical regression indicated that neuroticism was independently associated with greater pain catastrophizing and pain-related anxiety, above-and-beyond the contributions of sociodemographic characteristics, pain severity, and depression. A depression by neuroticism interaction was not observed, suggesting that associations between neuroticism and cognitive-affective pain constructs remained stable across varying levels of current depression. These findings represent an early but important step towards the clarification of complex associations between trait neuroticism, current depression, and tendencies toward catastrophic and anxiety-provoking appraisals of pain among persons seeking treatment for chronic pain.

  6. Associations between Neuroticism and Depression in Relation to Catastrophizing and Pain-Related Anxiety in Chronic Pain Patients.

    Directory of Open Access Journals (Sweden)

    Sandeep Kadimpati

    Full Text Available Several cognitive-affective constructs, including pain catastrophizing and pain-related anxiety, have been implicated in the onset and progression of chronic pain, and both constructs have been identified as key targets for multidisciplinary pain treatment. Both neuroticism and depression have been linked to these constructs (and to each other, but how each may contribute to the pain experience is unknown. This study tested associations between neuroticism, depression, and indices of catastrophizing and pain-related anxiety among persons seeking treatment for chronic non-malignant pain. We hypothesized, as a higher-order personality trait, neuroticism would remain uniquely associated with both pain catastrophizing and pain-related anxiety, even after accounting for current symptoms of depression. A retrospective study design assessed depression (as measured by the Centers for Epidemiologic Studies-Depression scale, neuroticism (measured with the Neuroticism-Extraversion-Openness Personality Inventory, the Pain Catastrophizing Scale, and the Pain Anxiety Symptom Score in a consecutive series of patients (n=595 admitted to a 3-week outpatient pain treatment program from March 2009 through January 2011. Hierarchical regression indicated that neuroticism was independently associated with greater pain catastrophizing and pain-related anxiety, above-and-beyond the contributions of sociodemographic characteristics, pain severity, and depression. A depression by neuroticism interaction was not observed, suggesting that associations between neuroticism and cognitive-affective pain constructs remained stable across varying levels of current depression. These findings represent an early but important step towards the clarification of complex associations between trait neuroticism, current depression, and tendencies toward catastrophic and anxiety-provoking appraisals of pain among persons seeking treatment for chronic pain.

  7. A population-based, incidence cohort study of mid-back pain after traffic collisions

    DEFF Research Database (Denmark)

    Johansson, M S; Boyle, E; Hartvigsen, Jan;

    2015-01-01

    data from a population-based inception cohort of all traffic injuries occurring in Saskatchewan, Canada, during a 2-year period were used. Annual overall and age-sex-specific incidence rates were calculated, the course of recovery was described using the Kaplan-Meier technique, and associations between...... participant characteristics and time-to-self-reported recovery were explored in 3496 MBP cases using Cox proportional hazards models. RESULTS: The yearly incidence rate was 236 per 100,000 population during the study period, and was highest in women and in young persons. The median time-to-first reported......BACKGROUND: Traffic collisions often result in a wide range of symptoms included in the umbrella term whiplash-associated disorders. Mid-back pain (MBP) is one of these symptoms. The incidence and prognosis of different traffic injuries and their related conditions (e.g. neck pain, low back pain...

  8. Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations (II): thrombocytopenia and skin manifestations.

    Science.gov (United States)

    Cervera, R; Tektonidou, M G; Espinosa, G; Cabral, A R; González, E B; Erkan, D; Vadya, S; Adrogué, H E; Solomon, M; Zandman-Goddard, G; Shoenfeld, Y

    2011-02-01

    The objectives of the 'Task Force on Catastrophic Antiphospholipid Syndrome (APS) and Non-criteria APS Manifestations' were to assess the clinical utility of the international consensus statement on classification criteria and treatment guidelines for the catastrophic APS, to identify and grade the studies that analyze the relationship between the antiphospholipid antibodies and the non-criteria APS manifestations, and to present the current evidence regarding the accuracy of these non-criteria APS manifestations for the detection of patients with APS. This article summarizes the studies analyzed on thrombocytopenia and skin manifestations, and presents the recommendations elaborated by the Task Force after this analysis.

  9. Polar catastrophe, electron leakage, and magnetic ordering at the LaMnO$_3$/SrMnO$_3$ interface

    OpenAIRE

    Nanda, B. R. K.; Satpathy, S.

    2009-01-01

    Electronic reconstruction at the polar interface LaMnO$_3$/SrMnO$_3$ (LMO/SMO) (100) resulting from the polar catastrophe is studied from a model Hamiltonian that includes the double and super exchange interactions, the Madelung potential, and the Jahn-Teller coupling terms relevant for the manganites. We show that the polar catastrophe, originating from the alternately charged LMO layers and neutral SMO layers, is quenched by the accumulation of an extra half electron per cell in the interfa...

  10. The geomorphic impact of catastrophic glacier ice loss in mountain regions

    Science.gov (United States)

    Evans, S. G.

    2006-12-01

    Perhaps the most dramatic manifestation of global warming is catastrophic glacier ice loss in mountain regions. The geomorphic impact of this process was first outlined by Evans and Clague in 1994 and includes mountain slope instability, glacier avalanching, the formation and failure of moraine dammed lakes, and the formation and failure of ice dammed lakes. The present paper is an update of the 1994 publication and has three components. First, a global review of recent glacier-related geomorphic events is undertaken. Second, an analysis of two cases from the Coast Mountains of British Columbia - the 1975 Devastation Glacier landslide and the 1983 Nostetuko Lake outburst resulting from the failure of a moraine dam illustrates the interaction of glacier ice loss and related geomorphic events. At Devastation Glacier, approximately 13 M m3 of altered Quaternary volcanic rock and glacier ice was lost from the west flank of Pylon Peak in the Mount Meager volcanic complex. The events were initiated by a catastrophic rockslide, involving altered Quaternary pyroclastic rocks, which continued down Devastation Creek valley as a high velocity debris avalanche. The overall length of the slide path was 7 km and the vertical height of the path was 1220 m yielding a fahrboschung of 10°. Other large landslides occurred in Devastation Creek valley in 1931 and 1947. Stability analysis of the initial failure shows that the 1975 rockslide was the result of a complex history of glacial erosion, loading and unloading of the toe of the slide mass caused by the Little Ice Age advance and subsequent retreat of Devastation Glacier. The shearing resistance along the base of the rockslide mass was reduced prior to 1975 by substantial previous slope displacements related to glacial ice loss. Some of this displacement is likely to have occurred as subglacial slope deformation since ice fall and crevasse patterns suggest the presence of slide like shearing displacements below the base of

  11. Earthquake and the Catastrophic End of the Late Bronze Age in the Eastern Mediterranean

    Science.gov (United States)

    Nur, A.

    2009-04-01

    The reasons for the catastrophic and wide spread political as well as physical collapse in the Aegean and Eastern Mediterranean areas that define the end of the Bronze age ca. 1225 BC to 1175 BC remain a major enigma. It has been attributed by historian to attacks by outsiders with the most favored group being the (enigmatic) so-called sea people. Unfortunately there is no real evidence for this. However combined geological, geophysical and archaeological evidence suggests that earthquakes may have played a key role in this extraordinary collapse during the late 13th and early 12th centuries . Based on the instrumentally recorded earthquakes occurring in the Aegean and Eastern Mediterranean region during the 20th century, several events that have clear historical information, and the geography of seismically active faults it is obvious that numerous earthquakes of magnitude 6·5 or greater (enough to destroy modern buildings, let alone those of antiquity) occurred here frequently in the past. Furthermore major earthquakes often occur in this region in groups, known as ‘‘sequences'' or ‘‘storms'', in which one large quake is followed days, months, or a few years later by others elsewhere on the plate boundary fault lines. When a map of the areas in the Aegean and Eastern Mediterranean region shaken by 20th century  earthquakes of magnitude 6·5 and greater and with an intensity of VII or greater is overlaid on Robert Drews' map of sites destroyed in these same regions during the so-called ‘‘Catastrophe'' near the end of the Late Bronze Age, it is readily apparent that virtually all of these LBA sites lie within the affected (‘‘high-shaking'') areas. This would suggest that a major ‘‘earthquake storm'' may have occurred in the Late Bronze Age Aegean and Eastern Mediterranean during the years 1225-1175 . This ‘‘storm'' may have interacted with societal, political and economic forces at work in these areas c. 1200  and

  12. Calibration and validation of earthquake catastrophe models. Case study: Impact Forecasting Earthquake Model for Algeria

    Science.gov (United States)

    Trendafiloski, G.; Gaspa Rebull, O.; Ewing, C.; Podlaha, A.; Magee, B.

    2012-04-01

    Calibration and validation are crucial steps in the production of the catastrophe models for the insurance industry in order to assure the model's reliability and to quantify its uncertainty. Calibration is needed in all components of model development including hazard and vulnerability. Validation is required to ensure that the losses calculated by the model match those observed in past events and which could happen in future. Impact Forecasting, the catastrophe modelling development centre of excellence within Aon Benfield, has recently launched its earthquake model for Algeria as a part of the earthquake model for the Maghreb region. The earthquake model went through a detailed calibration process including: (1) the seismic intensity attenuation model by use of macroseismic observations and maps from past earthquakes in Algeria; (2) calculation of the country-specific vulnerability modifiers by use of past damage observations in the country. The use of Benouar, 1994 ground motion prediction relationship was proven as the most appropriate for our model. Calculation of the regional vulnerability modifiers for the country led to 10% to 40% larger vulnerability indexes for different building types compared to average European indexes. The country specific damage models also included aggregate damage models for residential, commercial and industrial properties considering the description of the buildings stock given by World Housing Encyclopaedia and the local rebuilding cost factors equal to 10% for damage grade 1, 20% for damage grade 2, 35% for damage grade 3, 75% for damage grade 4 and 100% for damage grade 5. The damage grades comply with the European Macroseismic Scale (EMS-1998). The model was validated by use of "as-if" historical scenario simulations of three past earthquake events in Algeria M6.8 2003 Boumerdes, M7.3 1980 El-Asnam and M7.3 1856 Djidjelli earthquake. The calculated return periods of the losses for client market portfolio align with the

  13. Usages des TIC et rapports a l’incertitude en situation de catastrophes naturelles

    Directory of Open Access Journals (Sweden)

    Claire Brossaud

    2008-11-01

    Full Text Available Cet article montre comment des professionnels et des sinistrés qui ont été confrontés à des catastrophes naturelles sur trois territoires distincts - la tempête à Limoges en 1999, les inondations à Abbeville (2001 et à Bourg-en-Bresse (2005 - ont construit une histoire commune du risque au moyen des technologies de l’information et de la communication (TIC : Internet, téléphone portable, bases de données, outils de travail partagés, etc. Les usages des TIC sont d’abord resitués concrètement avant, pendant et après les événements dans un contexte historique où les sciences et techniques sont de plus en plus sollicitées pour réduire les incertitudes liées aux menaces sanitaires et écologiques. On voit ensuite s’élaborer une culture du risque sur la base de compétences socio-cognitives et relationnelles particulières face aux événements et à leur prise en charge technologique. Nous examinons en dernier ressort le rôle des TIC dans l’apprentissage d’une argumentation et d’une délibération collective sur les catastrophes, notamment grâce à la mise en place d’outils dédiés à l’étude sur le site http://www.technorisque.net.This article shows how professionnals and disaster victims involved in natural catastrophes in three different areas - Limoges storm in 1999, Abbeville and Bourg-en-Bresse floods in 2001 and 2005 – built a commun risk story with Information and communication technologies (ICT : Internet, mobiles, data bases, groupware, etc. At first, ICT uses are concretely approached before, during and after the events in a historic context where sciences and technology are growing up to reduce uncertainties of medical and ecological threats. Then, in the second part of this article, a risk culture is supported by socio-cognitive and relationnal competences towards events and their technological holding. At last, we examine ICT place in a collective argumentation and deliberation about the

  14. Generation of Vertically Incident Seismograms,

    Science.gov (United States)

    1985-09-01

    p. 106, equation 3.38.) %lPHASE Flag: If set, Minimum- phase filter required; otherwise, Zero phase %ILNR Counter of model file input lines, used in... PHASE ) FILTER -TYPE DB SLOPE CUT-OFF FREQUENCY 1 72 70 2 72 30 4’ 4 GENERATION OF VERTICALLY INCIDENT SEISMOGRAMS VISP; PLOTS OF PARAMETERS TEST I...FILTER PHASE 1 (MINIMUM PHASE ) FILTER -TYPE DB SLOPE CUT-OFF FREQUENCY 1 96 50 2 96 10 Table 6. Input data used to test a high-cult filter with zero phase

  15. Grazing incidence diffraction : A review

    Energy Technology Data Exchange (ETDEWEB)

    Gilles, B. [LTPCM, ENSEEG. St. Martin d`Heres. (France)

    1996-09-01

    Different Grazing Incidence Diffraction (GID) methods for the analysis of thin films and multilayer structures are reviewed in three sections: the reflectivity is developed in the first one, which includes the non-specular diffuse scattering. The second one is devoted to the extremely asymmetric Bragg diffraction and the third one to the in-plane Bragg diffraction. Analytical formulations of the scattered intensities are developed for each geometry, in the framework of the kinetical analysis as well as the dynamical theory. Experimental examples are given to illustrate the quantitative possibility of the GID techniques.

  16. Karner Blue Butterfly Recovery Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This recovery plan has been prepared by the Karner Blue Butterfly Recovery Team under the leadership of Dr. David Andow, University of Minnesota-St. Paul. Dr. John...

  17. A Cusp Catastrophe Model for Team Learning, Team Potency and Team Culture.

    Science.gov (United States)

    Rebelo, Teresa; Stamovlasis, Dimitrios; Lourenco, Paulo Renato; Dimas, Isabel; Pinheiro, Margarida

    2016-10-01

    This paper examines team learning behaviors within a nonlinear dynamical system (NDS) perspective. The present research is based on a sample of 36 project workgroups, where data were collected at two moments of their life cycle, with visual analogue scales. Using both the least squares method and maximum likelihood, it proposes a cusp catastrophe model for explaining team learning. The cusp model is superior to its linear alternatives and implements team culture as the asymmetry variable and team potency as bifurcation. The findings of cusp structure in the data support the existence of discontinuous shifts in learning behavior and furthermore a proposition that the punctuated equilibrium model (PEM) might be a reasonable model for describing group functioning, since it encompasses such sudden changes between distinct stages (attractors). A discussion on small group research is also provided by highlighting the nonlinear dynamics of team processes, along with further implications for research and practice.

  18. The catastrophic final flooding of Doggerland by the Storegga Slide tsunami

    Directory of Open Access Journals (Sweden)

    Bernhard Weninger

    2008-12-01

    Full Text Available Around 8200 calBP, large parts of the now submerged North Sea continental shelf (‘Doggerland’ were catastrophically flooded by the Storegga Slide tsunami, one of the largest tsunamis known for the Holocene, which was generated on the Norwegian coastal margin by a submarine landslide. In the present paper, we derive a precise calendric date for the Storegga Slide tsunami, use this date for reconstruction of contemporary coastlines in the North Sea in relation to rapidly rising sea-levels, and discuss the potential effects of the tsunami on the contemporaneous Mesolithic population. One main result of this study is an unexpectedly high tsunami impact assigned to the western regions of Jutland.

  19. Behavioral and catastrophic drift of invertebrates in two streams in northeastern Wyoming

    Science.gov (United States)

    Wangsness, David J.; Peterson, David A.

    1980-01-01

    Invertebrate drift samples were collected in August 1977 from two streams in the Powder River structural basin in northeastern Wyoming. The streams are Clear Creek, a mountain stream, and the Little Powder River, a plains stream. Two major patterns of drift were recognized. Clear Creek was sampled during a period of normal seasonal conditions. High drift rates occurred during the night indicating a behavioral drift pattern that is related to the benthic invertebrate density and carrying capacity of the stream substrates. The mayfly genes Baetis, a common drift organism, dominated the peak periods of drift in Clear Creek. The Little Powder River has a high discharge during the study period. Midge larvae of the families Chironomidae and Ceratopogonidae, ususally not common in drift, dominated the drift community. The dominance of midge larvae, the presence of several other organisms not common in drift, and the high discharge during the study period caused a catastrophic drift pattern. (USGS)

  20. Progression of antiphospholipid antibody syndrome to catastrophic antiphospholipid antibody syndrome acutely with cessation of antithrombotic therapy.

    Science.gov (United States)

    Katikireddi, V S; Kandiah, D A

    2012-05-01

    Catastrophic antiphospholipid antibody syndrome (CAPS) is a serious condition that is often unrecognised with a high mortality. Cessation of anticoagulation in antiphospholipid antibody syndrome (APS) can have devastating consequences with progression to CAPS. Making a diagnosis of APS can however be challenging because of the evolving diagnostic criteria and difficulty in confirming thromboses. Management of these patients can also be complex, especially in those with coexistent thrombocytopenia. New potential treatments are emerging targeted on the immunomodulation of APS rather than just prevention of thrombosis. This article aims to highlight these diagnostic and management difficulties by reporting and discussing three cases of APS with progression to CAPS following cessation of anticoagulation, one with fatal consequences, with confirmation of CAPS on autopsy, and two with successful treatment and outcomes.

  1. Catastrophic antiphospholipid antibody syndrome in a young woman in the postpartum period.

    Science.gov (United States)

    Jacobson, Tatiana B; Kolade, Victor O; Kapadia, Avni S

    2010-01-01

    A 27-year-old Hispanic female was admitted to hospital with fever, a sudden marked decrease in vision, and multi-organ failure shortly after preterm delivery by cesarean section for eclampsia. Her past history was significant for a spontaneous first trimester abortion and one live birth complicated by intrauterine growth retardation. She was found to have several focal brain infarcts, exudative retinal detachment, bilateral adrenal hemorrhage, renal insufficiency, hypertension and subsequently hypotension. Positive anticardiolipin antibodies, lupus anticoagulant, and anti-B2 glycoprotein-I, as well as deranged coagulation profile and PTT mixing studies aided in the diagnosis of catastrophic antiphospholipid antibody syndrome. Anticoagulation and high-dose intravenous steroids led to significant improvement in the patient's condition, including her vision.

  2. Psychological resilience, pain catastrophizing, and positive emotions: perspectives on comprehensive modeling of individual pain adaptation.

    Science.gov (United States)

    Sturgeon, John A; Zautra, Alex J

    2013-03-01

    Pain is a complex construct that contributes to profound physical and psychological dysfunction, particularly in individuals coping with chronic pain. The current paper builds upon previous research, describes a balanced conceptual model that integrates aspects of both psychological vulnerability and resilience to pain, and reviews protective and exacerbating psychosocial factors to the process of adaptation to chronic pain, including pain catastrophizing, pain acceptance, and positive psychological resources predictive of enhanced pain coping. The current paper identifies future directions for research that will further enrich the understanding of pain adaptation and espouses an approach that will enhance the ecological validity of psychological pain coping models, including introduction of advanced statistical and conceptual models that integrate behavioral, cognitive, information processing, motivational and affective theories of pain.

  3. Cosmology or Catastrophe? A non-minimally coupled scalar in an inhomogeneous universe

    CERN Document Server

    Caputa, Pawel; Olson, Joseph; Underwood, Bret

    2013-01-01

    A non-minimally coupled scalar field can have, in principle, a negative effective Planck mass squared which depends on the scalar field. Surprisingly, an isotropic and homogeneous cosmological universe with a non-minimally coupled scalar field is perfectly smooth as the rolling scalar field causes the effective Planck mass to change sign and pass through zero. However, we show that any small deviations from homogeneity diverge as the effective Planck mass vanishes, with catastrophic consequences for the cosmology. The physical origin of the divergence is due to the presence of non-zero scalar anisotropic stress from the non-minimally coupled scalar field. Thus, while the homogeneous and isotropic cosmology appears surprisingly sensible when the effective Planck mass vanishes, inhomogeneities tell a different story.

  4. Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication.

    Science.gov (United States)

    Holmes, J Bradley; Akman, Gokhan; Wood, Stuart R; Sakhuja, Kiran; Cerritelli, Susana M; Moss, Chloe; Bowmaker, Mark R; Jacobs, Howard T; Crouch, Robert J; Holt, Ian J

    2015-07-28

    Encoding ribonuclease H1 (RNase H1) degrades RNA hybridized to DNA, and its function is essential for mitochondrial DNA maintenance in the developing mouse. Here we define the role of RNase H1 in mitochondrial DNA replication. Analysis of replicating mitochondrial DNA in embryonic fibroblasts lacking RNase H1 reveals retention of three primers in the major noncoding region (NCR) and one at the prominent lagging-strand initiation site termed Ori-L. Primer retention does not lead immediately to depletion, as the persistent RNA is fully incorporated in mitochondrial DNA. However, the retained primers present an obstacle to the mitochondrial DNA polymerase γ in subsequent rounds of replication and lead to the catastrophic generation of a double-strand break at the origin when the resulting gapped molecules are copied. Hence, the essential role of RNase H1 in mitochondrial DNA replication is the removal of primers at the origin of replication.

  5. Risk finance for catastrophe losses with Pareto-calibrated Lévy-stable severities.

    Science.gov (United States)

    Powers, Michael R; Powers, Thomas Y; Gao, Siwei

    2012-11-01

    For catastrophe losses, the conventional risk finance paradigm of enterprise risk management identifies transfer, as opposed to pooling or avoidance, as the preferred solution. However, this analysis does not necessarily account for differences between light- and heavy-tailed characteristics of loss portfolios. Of particular concern are the decreasing benefits of diversification (through pooling) as the tails of severity distributions become heavier. In the present article, we study a loss portfolio characterized by nonstochastic frequency and a class of Lévy-stable severity distributions calibrated to match the parameters of the Pareto II distribution. We then propose a conservative risk finance paradigm that can be used to prepare the firm for worst-case scenarios with regard to both (1) the firm's intrinsic sensitivity to risk and (2) the heaviness of the severity's tail.

  6. Substantial contribution of anthropogenic air pollution to catastrophic floods in Southwest China

    Science.gov (United States)

    Fan, Jiwen; Rosenfeld, Daniel; Yang, Yan; Zhao, Chun; Leung, L. Ruby; Li, Zhanqing

    2015-07-01

    Extreme weather events have become more frequent and are likely linked to increases in greenhouse gases and aerosols, which alter the Earth's radiative balance and cloud processes. On 8-9 July 2013, a catastrophic flood devastated the mountainous area to the northwest of the Sichuan Basin. Atmospheric simulations at a convection-permitting scale with aerosols and chemistry included show that heavy air pollution trapped in the basin significantly enhances the rainfall intensity over the mountainous areas through "aerosol-enhanced conditional instability." That is, aerosols suppress convection by absorbing solar radiation and increasing atmospheric stability in the basin during daytime. This allows excess moist air to be transported to the mountainous areas and orographically lifted, generating strong convection and extremely heavy precipitation at night. We show that reducing pollution in the Sichuan Basin can effectively mitigate floods. It is suggested that coupling aerosol with meteorology can be crucial to improve weather forecast in polluted regions.

  7. Evaluation of social vulnerability to floods in Huaihe River basin: a methodology based on catastrophe theory

    Science.gov (United States)

    You, W. J.; Zhang, Y. L.

    2015-08-01

    Huaihe River is one of the seven largest rivers in China, in which floods occurred frequently. Disasters cause huge casualties and property losses to the basin, and also make it famous for high social vulnerability to floods. Based on the latest social-economic data, the index system of social vulnerability to floods was constructed, and Catastrophe theory method was used in the assessment process. The conclusion shows that social vulnerability as a basic attribute attached to urban environment, with significant changes from city to city across the Huaihe River basin. Different distribution characteristics are present in population, economy, flood prevention vulnerability. It is important to make further development of social vulnerability, which will play a positive role in disaster prevention, improvement of comprehensive ability to respond to disasters.

  8. Eculizumab Induces Sustained Remission in a Patient With Refractory Primary Catastrophic Antiphospholipid Syndrome.

    Science.gov (United States)

    Zikos, Thomas A; Sokolove, Jeremy; Ahuja, Neera; Berube, Caroline

    2015-09-01

    Catastrophic antiphospholipid syndrome (CAPS) is fatal in approximately 44% of patients in whom the diagnosis is made, thus demonstrating the inadequacy of current medical therapy. In this report, we discuss a 47-year-old man with a known history of primary antiphospholipid syndrome, who presented with CAPS after undergoing cholecystectomy and a treatment-refractory early relapse after development of colitis. Given the potential therapeutic efficacy of complement inhibition in antiphospholipid syndrome, the patient was administered eculizumab, a terminal complement inhibitor. Progressive clinical improvement and laboratory improvement were observed upon initiation of eculizumab. He has remained in remission for over 16 months of follow-up while on eculizumab. In conclusion, this case represents successful use of eculizumab for the treatment of primary CAPS.

  9. Vascular Endothelial Cell Function in Catastrophic Antiphospholipid Syndrome: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    B. Routy

    2013-01-01

    Full Text Available Catastrophic antiphospholipid syndrome (CAPS is a rare autoimmune condition, which has been associated with a high mortality rate. However, with current management that includes a combination of anticoagulation, glucocorticoid administration, and plasma exchange, mortality rate has declined. Despite survival improvement with new generation immunosuppressive agents, their mechanisms of action are poorly defined, and CAPS is still considered a high-risk complication in patients known with antiphospholipid antibody syndrome. Herein, we present a case of a 79-year-old male who presented with a myocardial infarct and renal failure secondary to CAPS following a splenectomy for immune thrombocytopenia. Regardless of rapid combination of first-line treatment and rituximab therapy, the patient developed lethal cardiogenic shock secondary to mitral valve papillary muscle necrosis. Discussion of the pathophysiology and avenues of future therapies in CAPS are reported.

  10. Preventing catastrophes in spatially extended systems through dynamic switching of random interactions

    Indian Academy of Sciences (India)

    Anshul Choudhary; Vivek Kohar; Sudeshna Sinha

    2015-02-01

    In this paper, we review and extend the results from our recently published work [Scientific Reports (Nature) 4, 4308] on taming explosive growth in spatially extended systems. Specifically, we consider collections of relaxation oscillators, which are relevant to modelling phenomena ranging from engineering to biology, under varying coupling topologies. We find that the system witnesses unbounded growth under regular connections on a ring, for sufficiently strong coupling strengths. However, when a fraction of the regular connections are dynamically rewired to random links, this blow-up is suppressed. We present the critical value of random links necessary for successful prevention of explosive growth in the oscillators for varying network rewiring time-scales. Further, we outline our analysis on the possible mechanisms behind the occurrence of catastrophes and how the switching of links helps to suppress them.

  11. Columnar order in jammed LiFePO4 cathodes: ion transport catastrophe and its mitigation.

    Science.gov (United States)

    Smith, Kyle C; Mukherjee, Partha P; Fisher, Timothy S

    2012-05-21

    The high-rate, high-capacity potential of LiFePO4-based lithium-ion battery cathodes has motivated numerous experimental and theoretical studies aiming to realize such performance through nano-sizing, tailoring of particle shape through synthesis conditions, and doping. Here, a granular mechanics study of microstructures formed by dense jammed packings of experimentally and theoretically inspired LiFePO4 particle shapes is presented. A strong dependence of the resultant packing structures on particle shapes is observed, in which columnar structures aligned with the [010] direction inhibit diffusion along [010] in anisotropic LiFePO4. Transport limitations are induced by [010] columnar order and lead to catastrophic performance degradation in anisotropic LiFePO4 electrodes. Further, judicious mixing of nanoplatelets with additive nanoparticles can frustrate columnar ordering and thereby enhance the rate capability of LiFePO4 electrodes by nearly an order of magnitude.

  12. Surviving catastrophic disintegration of a large left atrial myxoma: the importance of multi-disciplinary team.

    Science.gov (United States)

    Habbab, Louay; Alfaraidi, Haifa; Lamy, Andre

    2014-09-12

    Atrial myxomas are the most common primary cardiac tumors, representing ∼50% of all benign cardiac tumors. Patients with a left atrial myxoma (LAM) generally present with symptoms of mechanical obstruction of blood flow, systemic emboli or constitutional symptoms. Embolic complications may occur any time with progression of the tumor; therefore, myxoma is usually considered an indication for urgent surgery. This report describes a patient with mobile large LAM who survived multiple emboli to the brain, spleen, kidneys, abdominal aorta and lower limbs during hospitalization for surgery, illustrating the critical nature of this finding and its possible catastrophic complications and demonstrating the importance of multi-disciplinary team in the decision-making process and the management of such complications and supporting the hypothesis that intravenous thrombolysis may be safely used in the treatment of embolic stroke due to cardiac myxoma.

  13. Super Persistent Chaotic Transients And Catastrophic Bifurcation From Riddled To Fractal Basins

    CERN Document Server

    Andrade, V A

    2002-01-01

    This dissertation treats two related problems in chaotic dynamics: (1) super persistent chaotic transients in physical systems, and (2) catastrophic bifurcation from riddled to fractal basins. For the first problem, we investigate super persistent chaotic transient by studying the effect of noise on phase synchronization of coupled chaotic oscillators. A super persistent chaotic transient is typically induced by an unstable-unstable pair bifurcation in which two unstable periodic orbits of the same period coalesce and disappear as a system parameter is changed through a critical value. So far examples illustrating this type of transient chaos utilize discrete-time maps. We present a class of continuous-time dynamical systems that exhibit super persistent chaotic transients in parameter regimes of positive measure. In particular, we examine the effect of noise on phase synchronization of coupled chaotic oscillators. It is found that additive white noise can induce phase slips in integer multi...

  14. Classification of inflationary Einstein-scalar-field-models via catastrophe theory

    CERN Document Server

    Kusmartsev, F V; Obukhov, N; Schunck, E; Kusmartsev, V; Mielke, W; Obukhov, N; Schunck, E

    1995-01-01

    Various scenarios of the initial inflation of the universe are distinguished by the choice of a scalar field {\\em potential} U(\\phi) which simulates a {\\it temporarily} non--vanishing {\\em cosmological term}. Our new method, which involves a reparametrization in terms of the Hubble expansion parameter H, provides a classification of allowed inflationary potentials and of the stability of the critical points. It is broad enough to embody all known {\\it exact} solutions involving one scalar field as special cases. Inflation corresponds to the evolution of critical points of some catastrophe manifold. The coalescence of its nondegenerate critical points with the creation of a degenerate critical point corresponds the reheating phase of the universe. This is illustrated by several examples.

  15. Acknowledging Fascination with Catastrophe and Terrorism: September 11 and the Nuclear Destruction of Hiroshima/Nagasaki

    Directory of Open Access Journals (Sweden)

    Emmanouil Aretoulakis

    2014-07-01

    Full Text Available At the end of the twentieth century there was a critical shift from prioritizing the anti-aesthetic and the “sublime” towards favoring beauty in aesthetic as well as political matters. In this context, the present article discusses the role of beauty and aesthetics in such major disasters as the September 11 terrorist attacks and the Hiroshima/Nagasaki nuclear bombings. More specifically, it posits that there is a morally unacceptable feeling of fascination when witnessing destructive events of such magnitude. On the other hand, aesthetic appreciation is paradoxically indispensable for an ethical assessment of man-made catastrophes. Keywords: Beauty, Hiroshima, 9/11, Terrorism, Aesthetic Judgment, Imagination, Ethics.

  16. Predicting the timescales of catastrophic stratovolcano collapse - A model based on Mt. Taranaki, New Zealand.

    Science.gov (United States)

    Zernack, A. V.; Procter, J. N.; Cronin, S. J.; Bebbington, M. S.; Price, R. C.; Smith, I. E. M.

    2012-04-01

    Andesitic stratovolcanoes or composite volcanoes are constructed in short, but rapid growth-rate eruption episodes to form steep, unstable edifices made of alternating layers of lavas, pyroclastic and epiclastic breccias. Stratovolcanoes regularly collapse catastrophically, producing highly destructive volcanic debris avalanches that present the extreme hazard scenario at all major continental volcanic arcs on Earth. However, models to forecast their likelihood and size are rare, typically because of poor age and volume constraints on their deposits in the geological record at any one volcano. Here we use one of the best-exposed long-term records of both volcanic sedimentation and geochemical evolution from a typical calc-alkaline andesitic volcano to develop a steady-state growth and volume-controlled model for the probability of catastrophic volcanic edifice collapse. The >130 kyrs history of Mt. Taranaki (2518 m) in New Zealand's North Island is punctuated by at least 14 catastrophic edifice failures. These involved all sectors of the volcano and produced debris avalanche deposits of >1 to >7.5 km3 with recurrence intervals of 2.5-15 kyrs. The largest of these sudden events removed as much as one third of the upper present-day equivalent cone. Individual debris avalanche units show similar sedimentary and geomorphic characteristics, suggesting that the nature of proto-edifices, failure trigger mechanisms and runout path conditions were similar for each event. Each collapse was followed by sustained renewed volcanism and cone regrowth, although there are no matching stepwise geochemical changes in the magma erupted. Instead a stable, slowly evolving magmatic system has prevailed, producing similar eruption styles and frequency throughout the volcanic history. The strong climate variations and extreme conditions during the Last Glacial are also uncorrelated with the timing or magnitudes of edifice collapse. These similar internal and external conditions resulted

  17. Transient Loschmidt Echo and Orthogonality Catastrophe in highly excited Quantum Ising Spin Chains

    Science.gov (United States)

    Schiro, Marco; Lupo, Carla

    We study the response to sudden local perturbations of highly excited Quantum Ising Spin Chains. The key quantity encoding this response is the overlap between time-dependent wave functions, which we write as a transient Loschmidt echo. We compute the Echo perturbatively in the case of a weak local quench and study its asymptotics at long times, which contains crucial information about the structure of the highly excited non-equilibrium environment induced by the quench. Our results reveal that the Echo decays exponentially, rather than power law as in the low-energy Orthogonality Catastrophe, a further example of quench-induced decoherence. The emerging decoherence scale is set by the strenght of the local potential and the bulk excitation energy. In addition, the transient evolution features aging behavior at the Ising quantum critical point.

  18. Catastrophe mechanism and disaster countermeasure for soft rock roadway surrounding rock in Meihe mine

    Institute of Scientific and Technical Information of China (English)

    Yu Yang⇑; Zhu Caikun; Chong Deyu; Liu Yang; Li Sichao

    2015-01-01

    The soft rock’s heterogeneity and nonlinear mechanical behavior cause extremely difficult maintenance on the soft rock roadway. Aiming at the asymmetric deformation and destruction phenomenon appearing after excavating and supporting the 7101 air return way in Meihe mine, this paper comprehensively adopted a variety of methods to analyze the roadway surrounding rock deformation rule, obtaining the roadway surrounding rock stress and plastic zone distribution rule under no supporting condition and the roadway surrounding rock deformation features under original symmetric supporting condition. Furthermore, this paper revealed the catastrophe mechanism, and proposed the concept of‘weak struc-ture’ and the disaster countermeasure of‘overall stabilizing the roadway and strengthening the support of weak structure’ . The industrial test shows that the disaster control technology can realize the coordination deformation of the supporting structure and roadway surrounding rock, thus significantly controlling the deformation of roadway surrounding rock.

  19. On the possible physical mechanism of Chernobyl catastrophe and the unsoundness of official conclusion

    CERN Document Server

    Rukhadze, A A; Filippov, D V

    2003-01-01

    The official conclusion about the origin and mechanism of the Chernobyl catastrophe is shown to essentially contradict experimental facts available from the accident. In the frame of existing physical models of nuclear fission reactor, it is shown analytically that under conditions of the accident the period of runaway of reactor at the fourth power generating unit of the Chernobyl Nuclear Power Plant (CNPP) should be either 10 times slower or 100 times faster than that observed. A self-consistent hypothesis is suggested for the probable birth of magnetic charges, during the turbine generator test under it's own momentum test, at the fourth power generating unit of CNPP, and for the impact of these charges on the reactivity coefficient.

  20. STUDY ON CATASTROPHIC MECHANISM FOR ROTOR DROP TRANSIENT VIBRATION FOLLOWING MAGNETIC BEARING FAILURE

    Institute of Scientific and Technical Information of China (English)

    方之楚

    2002-01-01

    The nonlinear and transient vibration of a rotor, which dropped onto back-up bearings when its active magnetic bearings were out of order, was investigated. After strictly deriving its equations of motion and performing numerical simulations, the timehistories of rotating speed of the dropping rotor, and normal force at the rubbing contact point as well as the frequency spectrum of the vibration displacement of back-up bearings are fully analyzed. It is found that the strong and unsteady forced bending vibration of the unbalanced and damped rotor decelerating through its first bending vibtation of the unbalanced and damped rotor decelerating through its first critical speed as well as chattering at high frequencies caused by the nonlinearity at the rubbing contact point between the journal and back-up bearings may lead to the catastrophic damage of the system.

  1. From catastrophic acceleration to deceleration of liquid plugs in prewetted capillary tubes

    CERN Document Server

    Magniez, J C; Liu, C; Zoueshtiagh, F

    2016-01-01

    The dynamics of individual liquid plugs pushed at constant pressure head inside prewetted cylindrical capillary tubes is investigated experimentally and theoretically. It is shown that, depending on the thickness of the prewetting film and the magnitude of the pressure head, the plugs can either experience a continuous acceler ation leading to a catastrophic decrease of their size and eventually their rupture or conversely, a progressive deceleration associated with their growth. These behaviors are quantitatively reproduced with a simple nonlinear model [Baudoin et al., Proc. Nat. Ac. Sci. USA, 2013, 110, 859] adapted here for cylindrical channels. Furthermore, an analytical criterion for the transition between these two regimes is obtained and successfully compared with extensive experimental data. The implications of this work for pulmonary obstructive diseases are discussed.

  2. Modified Anderson orthogonality catastrophe power law in the presence of shell structure

    Science.gov (United States)

    Bandopadhyay, Swarnali; Hentschel, Martina

    2011-01-01

    We study Anderson orthogonality catastrophe (AOC) for parabolic quantum dots and focus on the effects of degeneracies, realized through the inherent shell structure of their energy levels that can be lifted through an external magnetic field, on the Anderson overlap. We find rich and interesting behaviors as a function of the strength and position of the perturbation, the system size, and the applied magnetic field. In particular, even for weak perturbations, we observe a pronounced AOC that is related to the degeneracy of energy levels. Most importantly, the power-law decay of the Anderson overlap as a function of the number of particles is modified in comparison to the metallic case due to the rearrangement of the energy-level shell structure. We support our analytical results by numerical calculations and also study the distribution of Anderson overlaps.

  3. Understanding reaction mechanisms in organic chemistry from catastrophe theory applied to the electron localization function topology.

    Science.gov (United States)

    Polo, Victor; Andres, Juan; Berski, Slawomir; Domingo, Luis R; Silvi, Bernard

    2008-08-07

    Thom's catastrophe theory applied to the evolution of the topology of the electron localization function (ELF) gradient field constitutes a way to rationalize the reorganization of electron pairing and a powerful tool for the unambiguous determination of the molecular mechanisms of a given chemical reaction. The identification of the turning points connecting the ELF structural stability domains along the reaction pathway allows a rigorous characterization of the sequence of electron pair rearrangements taking place during a chemical transformation, such as multiple bond forming/breaking processes, ring closure processes, creation/annihilation of lone pairs, transformations of C-C multiple bonds into single ones. The reaction mechanism of some relevant organic reactions: Diels-Alder, 1,3-dipolar cycloaddition and Cope rearrangement are reviewed to illustrate the potential of the present approach.

  4. Spontaneous recovery from acalculia.

    Science.gov (United States)

    Basso, Anna; Caporali, Alessandra; Faglioni, Pietro

    2005-01-01

    A topic much considered in research on acalculia was its relationship with aphasia. Far less attention has been given to the natural course of acalculia. In this retrospective study, we examined the relationship between aphasia and acalculia in an unselected series of 98 left-brain-damaged patients and the spontaneous recovery from acalculia in 92 acalculic patients with follow-up. There was a significant association between aphasia and acalculia although 19 participants exhibited aphasia with no acalculia and six acalculia with no aphasia. We observed significant improvement between a first examination carried out between 1 and 5 months post-onset and a second examination carried out between 3 and 11 months later (mean: 5 months). The mechanisms of spontaneous recovery are discussed.

  5. Gasoline Vapor Recovery

    Science.gov (United States)

    1979-01-01

    Gasoline is volatile and some of it evaporates during storage, giving off hydrocarbon vapor. Formerly, the vapor was vented into the atmosphere but anti-pollution regulations have precluded that practice in many localities, so oil companies and storage terminals are installing systems to recover hydrocarbon vapor. Recovery provides an energy conservation bonus in that most of the vapor can be reconverted to gasoline. Two such recovery systems are shown in the accompanying photographs (mid-photo at right and in the foreground below). They are actually two models of the same system, although.configured differently because they are customized to users' needs. They were developed and are being manufactured by Edwards Engineering Corporation, Pompton Plains, New Jersey. NASA technological information proved useful in development of the equipment.

  6. Recovery Systems Design Guide

    Science.gov (United States)

    1978-12-01

    14 1.9 Gemini Paraglider Deployment ......................................... 14 1.10 Apollo Recovery System Deployment...45 to 15 g’s. The fied land landing by Paraglider and an ejection seat automatic sequencing system deployed the drogue back-up system as the means for... Paraglider system should not be higher altitudes and speeds. There was no reserve ready for early Gemini flights. The intention was to drogue parachute

  7. Superconducting energy recovery linacs

    Science.gov (United States)

    Ben-Zvi, Ilan

    2016-10-01

    High-average-power and high-brightness electron beams from a combination of laser photocathode electron guns and a superconducting energy recovery linac (ERL) is an emerging accelerator science with applications in ERL light sources, high repetition rate free electron lasers , electron cooling, electron ion colliders and more. This paper reviews the accelerator physics issues of superconducting ERLs, discusses major subsystems and provides a few examples of superconducting ERLs.

  8. Complex chromosomal rearrangements by single catastrophic pathogenesis in NUT midline carcinoma

    Science.gov (United States)

    Lee, J.-K.; Louzada, S.; An, Y.; Kim, S. Y.; Kim, S.; Youk, J.; Park, S.; Koo, S. H.; Keam, B.; Jeon, Y. K.; Ku, J.-L.; Yang, F.; Kim, T. M.

    2017-01-01

    Background Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare aggressive malignancy often occurring in the tissues of midline anatomical structures. Except for the pathognomonic BRD3/4–NUT rearrangement, the comprehensive landscape of genomic alterations in NMCs has been unexplored. Patients and methods We investigated three NMC cases, including two newly diagnosed NMC patients in Seoul National University Hospital, and a previously reported cell line (Ty-82). Whole-genome and transcriptome sequencing were carried out for these cases, and findings were validated by multiplex fluorescence in situ hybridization and using individual fluorescence probes. Results Here, we present the first integrative analysis of whole-genome sequencing, transcriptome sequencing and cytogenetic characterization of NUT midline carcinomas. By whole-genome sequencing, we identified a remarkably similar pattern of highly complex genomic rearrangements (previously denominated as chromoplexy) involving the BRD3/4–NUT oncogenic rearrangements in two newly diagnosed NMC cases. Transcriptome sequencing revealed that these complex rearrangements were transcribed as very simple BRD3/4–NUT fusion transcripts. In Ty-82 cells, we also identified a complex genomic rearrangement involving the BRD4–NUT rearrangement underlying the simple t(15;19) karyotype. Careful inspections of rearrangement breakpoints indicated that these rearrangements were likely attributable to single catastrophic events. Although the NMC genomes had >3000 somatic point mutations, canonical oncogenes or tumor suppressor genes were rarely affected, indicating that they were largely passenger events. Mutational signature analysis showed predominant molecular clock-like signatures in all three cases (accounting for 54%−75% of all base substitutions), suggesting that NMCs may arise from actively proliferating normal cells. Conclusion Taken together, our findings suggest that a single catastrophic event in

  9. A test of catastrophic transition mechanisms in the Chihuahuan Desert Grassland

    Science.gov (United States)

    Svejcar, L.; Bestelmeyer, B.; Duniway, M.

    2012-12-01

    Dryland ecosystems are known to undergo transitions from grassland or savanna states to shrub-dominated and/or eroded states with persistent loss of herbaceous vegetation. Theoretical models for predicting critical thresholds between states have been examined in drylands to search for early warning indicators, yet there is scant empirical evidence for the mechanisms. The models postulate that larger patches are favorable environments for plant growth in arid ecosystems due to short-range facilitation. The breakdown of large patches is thought to trigger catastrophic transitions. We tested assumptions underpinning these models using an experiment in black grama grassland (Bouteloua eriopoda Torr.) of the Chihuahuan Desert in which variable grazing intensities produced a wide range of patch sizes in plots with differing mesquite shrub (Prosopis glandulosa Torr.) densities. We tested the hypothesis that growth, reproductive capability, and reproductive success of black grama plants would be greater in larger plant patches than in smaller patches. From 2010-2012 we measured numbers of stolons, ramets, rooted ramets and young individual plants associated with focal black grama plants and fixed areas within each patch. We found that the largest patches did not always feature the highest rates of grass reproduction across years, suggesting that patch size does not consistently indicate the patch persistence mechanisms proposed in catastrophic transition models. Other factors, such as resource competition within patches, may play important roles in black grama grasslands. When assessing rangeland conditions in the Chihuahuan desert grasslands, theoretical models of critical thresholds and early warning indicators should be applied with caution.

  10. Healthcare coalitions: the new foundation for national healthcare preparedness and response for catastrophic health emergencies.

    Science.gov (United States)

    Courtney, Brooke; Toner, Eric; Waldhorn, Richard; Franco, Crystal; Rambhia, Kunal; Norwood, Ann; Inglesby, Thomas V; O'Toole, Tara

    2009-06-01

    After 9/11 and the 2001 anthrax letters, it was evident that our nation's healthcare system was largely underprepared to handle the unique needs and large volumes of people who would seek medical care following catastrophic health events. In response, in 2002 Congress established the Hospital Preparedness Program (HPP) in the U.S. Department of Health and Human Services (HHS) to strengthen the ability of U.S. hospitals to prepare for and respond to bioterrorism and naturally occurring epidemics and disasters. Since 2002, the program has resulted in substantial improvements in individual hospitals' disaster readiness. In 2007, the HHS Office of the Assistant Secretary for Preparedness and Response (ASPR) contracted with the Center for Biosecurity of the University of Pittsburgh Medical Center to conduct an assessment of U.S. hospital preparedness and to develop tools and recommendations for evaluating and improving future hospital preparedness efforts. One of the most important findings from this work is that healthcare coalitions-collaborative groups of local healthcare institutions and response agencies that work together to prepare for and respond to emergencies-have emerged throughout the U.S. since the HPP began. This article provides an overview of the HPP and the Center's hospital preparedness research for ASPR. Based on that work, the article also defines healthcare coalitions and identifies their structure and core functions, provides examples of more developed coalitions and common challenges faced by coalitions, and proposes that healthcare coalitions should become the foundation of a national strategy for healthcare preparedness and response for catastrophic health events.

  11. Landscape evolution in relation with occurrence of gravitational slope deformation and catastrophic landslides

    Science.gov (United States)

    Tsou, Ching-Ying; Chigira, Masahiro; Matsushi, Yuki; Chen, Su-Chin

    2013-04-01

    The Central Range of Taiwan is an example of a tectonically active orogen. The topography of a mountainous catchment of the Dahan River in northern side of the Central Range exhibits V-shaped inner valleys where landsliding is the dominant process of hillslope erosion and bedrock rivers are incising into the landscape. We take two approaches including (i) the study of present day morphostructural features of gravitationally deformed slopes and (ii) the study of the relationship between the gravitational slope deformation and fluvial incision to research the linkage of gravitational slope deformations, catastrophic landslides, and landscape evolution for the prediction of potential sites of future landslides. Mapped deep-seated gravitational slope deformations and scars of rainfall-induced rock/debris avalanches imply that their distributions are closely related to three series of convex slope breaks relating to the rejuvenation of topography by a three-phase fluvial incision leaded by three series of knickpoints migration. Many shallow rock/debris avalanches have occurred below the lowest slope break. By contrast, majority of gravitational slope deformations have occurred at the margins of the highest slope break around the paleosurface remnants, suggesting that the rejuvenation caused debuttressing of hillslopes and subsequent stress-release led to large scale slope destabilization, resulting in gravitational slope deformations. Catastrophic landslides in many locations deem to be preceded by gravitational slope deformation of rocks with adverse geological structures, many of which are buckling of alternating beds of sandstone and mudstone, and toppling of argillite and slate. The gravitationally deformed slopes change the topography and remain for a long time, and commonly accompany with some other types of mass movements (e.g. debris flows, rock/debris avalanches, and rockfalls). The results suggest that landslides are strongly controlled by geomorphology and

  12. Quantification of tsunami-induced flows on a Mediterranean carbonate ramp reveals catastrophic evolution

    Science.gov (United States)

    Slootman, Arnoud; Cartigny, Matthieu J. B.; Moscariello, Andrea; Chiaradia, Massimo; de Boer, Poppe L.

    2016-06-01

    Cool-water carbonates are the dominant limestones in the Mediterranean Basin since the Early Pliocene. Their deposition typically resulted in ramp morphologies due to high rates of resedimentation. Several such fossil carbonate ramps are characterised by a bimodal facies stacking pattern, where background deposition of subaqueous dune and/or tempestite deposits is repeatedly interrupted by anomalously thick sedimentary units, dominated by backset-stratification formed by supercritical flows. A multitude of exceptional triggers (e.g. storms, floods, tsunamis) have been invoked to explain the origin of these supercritical flows, which, in the absence of a quantitative analysis, remains speculative as yet. Here, for the first time, the catastrophic evolution of one such Mediterranean carbonate ramp, on Favignana Island (Italy), is quantified by combining 87Sr/86Sr dating, outcrop-based palaeoflow reconstructions and hydraulic calculations. We demonstrate that rare tsunami-induced flows, occurring on average once every 14 to 35 kyr, lasting a few hours only, deposited the anomalously thick backset-bedded units that form half of the sedimentary record. In between such events, cumulative two years of storm-induced flows deposited the remaining half of the succession by the stacking of subaqueous dunes. The two to four orders of magnitude difference in average recurrence period between the two flow types, and their associated sedimentation rates, emphasises the genetic differences between the two styles of deposition. In terms of sediment transport, the studied carbonate ramp was inactive for at least 99% of the time with gradual progradation during decennial to centennial storm activity. Carbonate ramp evolution attained a catastrophic signature by the contribution of rare tsunamis, producing short-lived, high-energy sediment gravity flows.

  13. Catastrophic neurological complications of emergent endotracheal intubation: report of 2 cases.

    Science.gov (United States)

    Oppenlander, Mark E; Hsu, Forrest D; Bolton, Patrick; Theodore, Nicholas

    2015-05-01

    Although exceedingly rare, catastrophic neurological decline may result from endotracheal intubation of patients with preexisting cervical spine disease. The authors report on 2 cases of quadriplegia resulting from emergent endotracheal intubation in the intensive care unit. A 68-year-old man with ankylosing spondylitis became quadriplegic after emergent intubation. A new C6-7 fracturedislocation was identified, and the patient underwent emergent open reduction and C4-T2 posterior fixation and fusion. The patient remained quadriplegic and ultimately died of pneumonia 1 year later. This is the first report with radiographic documentation of a cervical fracture-dislocation resulting from intubation in a patient with ankylosing spondylitis. A 73-year-old man underwent posterior C6-T1 decompression and fixation for a C6-7 fracture. On postoperative Day 12, emergent intubation for respiratory distress resulted in C6-level quadriplegia. Imaging revealed acute spondyloptosis at C6-7, and the patient underwent emergent open reduction with revision and extension of posterior fusion from C-3 to T-2. He remained quadriplegic and ventilator dependent. Five days after the second operation, care was withdrawn. This is the first report of intubation as a cause of significant neurological decline related to disruption of a recently fixated cervical fracture. Risk factors are identified and pertinent literature is reviewed for cases of catastrophic neurological complications after emergent endotracheal intubation. Strategies for obtaining airway control in patients with cervical spine pathology are also identified. Awareness of the potential dangers of airway management in patients with cervical spine pathology is critical for all involved subspecialty team members.

  14. Increasing incidence of diabetes after gestational diabetes

    DEFF Research Database (Denmark)

    Lauenborg, Jeannet; Hansen, Torben; Jensen, Dorte Møller;

    2004-01-01

    To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes....

  15. Ionospheric Oblique Incidence Soundings by Satellites

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The oblique incidence sweep-frequency ionospheric sounding technique uses the same principle of operation as the vertical incidence sounder. The primary difference...

  16. USFA NFIRS 2013 Fire Incident & Cause Data

    Data.gov (United States)

    Department of Homeland Security — The 2013 Fire Causes & Incident data was provided by the U.S. Fire Administration’s (USFA) National Fire Data Center’s (NFDC’s) National Fire Incident Reporting...

  17. Recovery From Comorbidity

    Directory of Open Access Journals (Sweden)

    Mathew Carter

    2013-11-01

    Full Text Available Comorbidity among mood, anxiety, and alcohol disorders is common and burdensome, affecting individuals, families, and public health. A systematic and integrative review of the literature across disciplines and research methodologies was performed. Supradisciplinary approaches were applied to the review and the ensuing critical appraisal. Definitions, measurement, and estimation are controversial and inconstant. Recovery from comorbidity cannot be easily extricated from a sociocultural milieu. Methodological challenges in quantitative and qualitative research and across disciplines are many and are discussed. The evidence supporting current treatments is sparse and short-term, and modalities operating in isolation typically fail. People easily fall into the cracks between mental health and addiction services. Clinicians feel untrained and consumers bear the brunt of this: Judgmental and moralistic interactions persist and comorbidity is unrecognized in high-risk populations. Competing historical paradigms of mental illness and addiction present a barrier to progress and reductionism is an impediment to care and an obstacle to the integration and interpretation of research. What matters to consumers is challenging to quantify but worth considering: Finding employment, safe housing, and meaning are crucial to recovery. Complex social networks and peer support in recovery are important but poorly understood. The focus on modalities of limited evidence or generalizability persists in literature and practice. We need to consider different combinations of comorbidity, transitions as opposed to dichotomies of use or illness, and explore the long-term view and emic perspectives.

  18. A Study on Internal Service Recovery Strategy Using CIT from the First Line Staff’s Perspective

    Institute of Scientific and Technical Information of China (English)

    Guoqing HUANG; Pengfei XIE; Hong SHU

    2014-01-01

    Service is a special product. It is intangible and unstored, so service er-rors are not avoided. Once service errors appear, the first line staffs who keep di-rect touch with customers wil play an important role in service recovery. The staffs' negative emotions during the recovery service should be recovered by internal ser-vice recovery. In this paper, critical incident technique is applied to analyse the re-covery strategies expected by the first line staff and the internal service recovery strategies such as inspiring, authorization, training and psychology service are put forward. the strategy most expected by the staff is reward.

  19. Increasing incidence of diabetes after gestational diabetes

    DEFF Research Database (Denmark)

    Lauenborg, Jeannet; Hansen, Torben; Jensen, Dorte Møller

    2004-01-01

    To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes.......To study the incidence of diabetes among women with previous diet-treated gestational diabetes mellitus (GDM) in the light of the general increasing incidence of overweight and diabetes and to identify risk factors for the development of diabetes....

  20. Child's and parents' catastrophizing about pain is associated with procedural fear in children: a study in children with diabetes and their mothers.

    Science.gov (United States)

    Vervoort, T; Goubert, L; Vandenbossche, H; Van Aken, S; Matthys, D; Crombez, G

    2011-12-01

    The contribution of the child's and parents' catastrophizing about pain was explored in explaining procedural pain and fear in children. Procedural fear and pain were investigated in 44 children with Type I diabetes undergoing a finger prick. The relationships between parents' catastrophizing and parents' own fear and estimates of their child's pain were also investigated. The children and their mothers completed questionnaires prior to a routine consultation with the diabetes physician. Children completed a situation-specific measure of the Pain Catastrophizing Scale for Children (PCS-C) and provided ratings of their experienced pain and fear on a 0-10 numerical rating scale (NRS). Parents completed a situation-specific measure of the Pain Catastrophizing Scale For Parents (PCS-P) d provided estimates of their child's pain and their own experienced fear on a 0-10 NRS. Analyses indicated that higher catastrophizing by children was associated with more fear and pain during the finger prick. Scores for parents' catastrophzing about their children's pain were positively related to parents' scores for their own fear, estimates of their children's pain, and child-reported fear, but not the amount of pain reported by the child. The findings attest to the importance of assessing for and targeting child and parents' catastrophizing about pain. Addressing catastrophizing and related fears and concerns of both parents and children may be necessary to assure appropriate self-management. Further investigation of the mechanisms relating catastrophizing to deleterious outcomes is warranted.