WorldWideScience

Sample records for cataclysmic variable bb

  1. The winds of cataclysmic variables

    Energy Technology Data Exchange (ETDEWEB)

    Mauche, C.W. [Lawrence Livermore National Lab., CA (United States). Lab. for Experimental Astrophysics; Raymond, J.C. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (United States)

    1994-02-16

    The authors present an observational and theoretical review of the winds of cataclysmic variables (CVs). Specifically, they consider the related problems of the geometry and mass-loss rate of the winds of CVs, their ionization state and variability, and the results from studies of eclipsing CVs. Finally, they consider the properties of accretion disk wind models. Some of these models predict substantial angular momentum loss, which could affect both disk structure and binary evolution.

  2. EUVE Observations of Nonmagnetic Cataclysmic Variables

    Energy Technology Data Exchange (ETDEWEB)

    Mauche, C W

    2001-09-05

    The authors summarize EUVE's contribution to the study of the boundary layer emission of high accretion-rate nonmagnetic cataclysmic variables, especially the dwarf novae SS Cyg, U Gem, VW Hyi, and OY Car in outburst. They discuss the optical and EUV light curves of dwarf nova outbursts, the quasi-coherent oscillations of the EUV flux of SS Cyg, the EUV spectra of dwarf novae, and the future of EUV observations of cataclysmic variables.

  3. White dwarfs in cataclysmic variables

    Science.gov (United States)

    Gaensicke, Boris

    2016-07-01

    Cataclysmic variables (CVs) provide excellent laboratories to study the effect that the accretion of matter, energy and angular momentum has on the structure of white dwarfs, with important implications on the evolution of these compact binaries, the ignition of thermonuclear surface burning, and potentially their explosion as SNIa. I will provide an overview of our current understanding of CV white dwarfs, with a particular emphasis on the results of a recent large HST program. I will review our knowledge regarding the mass distribution of CV white dwarfs, as well as the secular mean accretion rates that can be inferred from their effective temperatures, and compare those statistics with predictions from CV population models. I will also discuss a sub-set of CVs which underwent thermal-time scale mass transfer, one of the channels that is often discussed as a pathway to SN Ia, and I will illustrate how the study of these "failed SNIa" can contribute to the discussion of SNIa progenitors. Finally, I will discuss the occurrence of non-radial pulsations in white dwarfs, both in CVs and their detached progenitors.

  4. Herschel Observations of Cataclysmic Variables

    CERN Document Server

    Harrison, Thomas E; Tappert, Claus; Hoffman, Douglas I; Campbell, Ryan K

    2012-01-01

    We have used the PACS instrument on the Herschel Space Observatory to observe eight cataclysmic variables at 70 and 160 microns. Of these eight objects, only AM Her was detected. We have combined the Herschel results with ground-based, Spitzer, and WISE observations to construct spectral energy distributions for all of the targets. For the two dwarf novae in the sample, SS Cyg and U Gem, we find that their infrared luminosities are completely dominated by their secondary stars. For the two highly magnetic "polars" in our survey, AM Her and EF Eri, we find that their mid-infrared excesses, previously attributed to circumbinary dust emission, can be fully explained by cyclotron emission. The WISE light curves for both sources show large, orbitally modulated variations that are identically phased to their near-IR light curves. We propose that significant emission from the lowest cyclotron harmonics (n

  5. ULTRACAM photometry of eclipsing cataclysmic variable stars

    CERN Document Server

    Feline, William James

    2008-01-01

    The accurate determination of the masses of cataclysmic variable stars is critical to our understanding of their origin, evolution and behaviour. Observations of cataclysmic variables also afford an excellent opportunity to constrain theoretical physical models of the accretion discs housed in these systems. In particular, the brightness distributions of the accretion discs of eclipsing systems can be mapped at a spatial resolution unachievable in any other astrophysical situation. This thesis addresses both of these important topics via the analysis of the light curves of six eclipsing dwarf novae, obtained using ULTRACAM, a novel high-speed imaging photometer.

  6. Mass transfer cycles in cataclysmic variables

    Science.gov (United States)

    King, A. R.; Frank, J.; Kolb, U.; Ritter, H.

    1995-01-01

    It is well known that in cataclysmic variables the mass transfer rate must fluctuate about the evolutionary mean on timescales too long to be directly observable. We show that limit-cycle behavior can occur if the radius change of the secondary star is sensitive to the instantaneous mass transfer rate. The only reasonable way in which such a dependence can arise is through irradiation of this star by the accreting component. The system oscillates between high states, in which irradiation causes slow expansion of the secondary and drives an elevated transfer rate, and low states, in which this star contracts.

  7. Cataclysmic Variables: Eight Breakthroughs in Eight Years

    CERN Document Server

    Knigge, Christian

    2011-01-01

    The last few years have seen tremendous progress in our understanding of cataclysmic variable stars. As a result, we are finally developing a much clearer picture of their evolution as binary systems, the physics of the accretion processes powering them, and their relation to other compact accreting objects. In this review, I will highlight some of the most exciting recent breakthroughs. Several of these have opened up completely new avenues of research that will probably lead to additional major advances over the next decade.

  8. Novalike Cataclysmic Variables in the Infrared

    CERN Document Server

    Hoard, D W; Howell, Steve B; Wachter, Stefanie; Brinkworth, Carolyn S; Knigge, Christian; Drew, J E; Szkody, Paula; Kafka, S; Belle, Kunegunda; Ciardi, David R; Froning, Cynthia S; van Belle, Gerard T; Pretorius, M L

    2014-01-01

    Novalike cataclysmic variables have persistently high mass transfer rates and prominent steady state accretion disks. We present an analysis of infrared observations of twelve novalikes obtained from the Two Micron All Sky Survey, the Spitzer Space Telescope, and the Wide-field Infrared Survey Explorer All Sky Survey. The presence of an infrared excess at >3-5 microns over the expectation of a theoretical steady state accretion disk is ubiquitous in our sample. The strength of the infrared excess is not correlated with orbital period, but shows a statistically significant correlation (but shallow trend) with system inclination that might be partially (but not completely) linked to the increasing view of the cooler outer accretion disk and disk rim at higher inclinations. We discuss the possible origin of the infrared excess in terms of emission from bremsstrahlung or circumbinary dust, with either mechanism facilitated by the mass outflows (e.g., disk wind/corona, accretion stream overflow, and so on) present...

  9. Searching for nova shells around cataclysmic variables

    CERN Document Server

    Sahman, D I; Knigge, C; Marsh, T R

    2015-01-01

    We present the results of a search for nova shells around 101 cataclysmic variables (CVs), using Halpha images taken with the 4.2-m William Herschel Telescope (WHT) and the 2.5-m Isaac Newton Telescope Photometric Halpha Survey of the Northern Galactic Plane (IPHAS). Both telescopes are located on La Palma. We concentrated our WHT search on nova-like variables, whilst our IPHAS search covered all CVs in the IPHAS footprint. We found one shell out of the 24 nova-like variables we examined. The newly discovered shell is around V1315 Aql and has a radius of approx.2.5 arcmin, indicative of a nova eruption approximately 120 years ago. This result is consistent with the idea that the high mass-transfer rate exhibited by nova-like variables is due to enhanced irradiation of the secondary by the hot white dwarf following a recent nova eruption. The implications of our observations for the lifetime of the nova-like variable phase are discussed. We also examined 4 asynchronous polars, but found no new shells around an...

  10. Novalike Cataclysmic Variables are Significant Radio Emitters

    CERN Document Server

    Coppejans, Deanne L; Miller-Jones, James C A; Rupen, Michael P; Knigge, Christian; Sivakoff, Gregory R; Groot, Paul J

    2015-01-01

    Radio emission from non-magnetic cataclysmic variables (CVs, accreting white dwarfs) could allow detailed studies of outflows and possibly accretion flows in these nearby, numerous and non-relativistic compact accretors. Up to now, however, very few CVs have been detected in the radio. We have conducted a VLA pilot survey of four close and optically-bright novalike CVs at 6 GHz, detecting three, and thereby doubling the number of radio detections of these systems. RW Sex, V603 Aql and the old nova TT Ari were detected in both of the epochs, while V1084 Her was not detected (to a $3\\sigma$ upper-limit of 7.8 $\\mu\\rm{Jy}\\,\\rm{beam}^{-1}$). These observations clearly show that the sensitivity of previous surveys was typically too low to detect these objects and that non-magnetic CVs can indeed be significant radio emitters. The three detected sources show a range of properties, including flaring and variability on both short ($\\sim$200 s) and longer-term (days) time-scales, as well as circular polarization level...

  11. Observations of Faint Eclipsing Cataclysmic Variables

    CERN Document Server

    Çamurdan, Dicle Zengin; Çamurdan, C Muzaffer

    2010-01-01

    We present time-resolved photometry of six faint (V>17mag) cataclysmic variables (CVs); one of them is V849 Oph and the others are identified from the Sloan Digital Sky Survey (SDSS J0920+0042, SDSS J1327+6528, SDSS J1227+5139, SDSS J1607.02+3623, SDSS J1457+5148). The optical CCD photometric observations of these objects were performed at the T\\"UB\\.ITAK National Observatory (Turkey) between February 2006 and March 2009. We aimed to detect short time scale orbital variability arisen from hot-spot modulation, flickering structures which occur from rapid fluctuations of material transferring from red star to white dwarf and orbital period changes for selected short-period (P<4h) CVs at quiescence. Results obtained from eclipse timings and light curves morphology related to white dwarf stars, accretion disks and hot-spots are discussed for each system. Analysis of the short time coverage of data, obtained for SDSS J1227+5139 indicates a cyclical period change arisen from magnetic activity on the secondary st...

  12. The Magnetospheric Boundary in Cataclysmic Variables

    CERN Document Server

    Hellier, Coel

    2013-01-01

    The magnetic cataclysmic variables (MCVs) present a wealth of observational diagnostics for studying accretion flows interacting with a magnetosphere. Spin-period pulsations from the rotation of the white dwarf are seen in optical light, in the UV and X-ray bands, and in polarimetry, and modelling these can constrain the size and location of the accretion footprints on the white-dwarf surface. Tracing these back along field lines can tell us about the transition region between the stream or disk and the magnetosphere. Further, optical emission lines give us velocity information, while analysis of eclipses gives spatial information. I discuss MCVs (particularly FO Aqr, V405 Aur, XY Ari and EX Hya, but also mentioning PQ Gem, GK Per, V2400 Oph, HT Cam, TX Col, AO Psc, AE Aqr, WZ Sge, V1223 Sgr and DQ Her), reviewing what observations tell us about the disk-magnetosphere boundary. The spin-period variations are caused by a mixture of geometric effects and absorption by the accretion flow, and appear to show that...

  13. White dwarf masses in cataclysmic variables

    CERN Document Server

    Wijnen, T P G; Schreiber, M R

    2015-01-01

    The white dwarf (WD) mass distribution of cataclysmic variables (CVs) has recently been found to dramatically disagree with the predictions of the standard CV formation model. The high mean WD mass among CVs is not imprinted in the currently observed sample of CV progenitors and cannot be attributed to selection effects. Two possibilities have been put forward: either the WD grows in mass during CV evolution, or in a significant fraction of cases, CV formation is preceded by a (short) phase of thermal time-scale mass transfer (TTMT) in which the WD gains a sufficient amount of mass. We investigate if either of these two scenarios can bring theoretical predictions and observations into agreement. We employed binary population synthesis models to simulate the present intrinsic CV population. We incorporated aspects specific to CV evolution such as an appropriate mass-radius relation of the donor star and a more detailed prescription for the critical mass ratio for dynamically unstable mass transfer. We also imp...

  14. Discovery of Fourier-dependent time lags in cataclysmic variables

    NARCIS (Netherlands)

    Scaringi, S.; Körding, E.; Groot, P.J.; Uttley, P.; Marsh, T.; Knigge, C.; Maccarone, T.; Dhillon, V.S.

    2013-01-01

    We report the first study of Fourier-frequency-dependent coherence and phase/time lags at optical wavelengths of cataclysmic variables (MV Lyr and LU Cam) displaying typical flickering variability in white light. Observations were performed on the William Herschel Telescope using ULTRACAM. Light

  15. Two Cataclysmic Variables Identified from ROSAT Bright Sources

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This paper presents the results of optical spectroscopic observations of two ROSAT bright sources, 1RXS J020928.9+283243 and 1RXS J042332.8+745300. The low-dispersion spectra suggest the cataclysmic variable classification for the two objects. Further photometric observations are expected to reveal the variable features and to confirm the classifications.

  16. High-Speed Photo-Polarimetry of Magnetic Cataclysmic Variables

    Directory of Open Access Journals (Sweden)

    S. B. Potter

    2015-02-01

    Full Text Available I review recent highlights of the SAAO High-speed Photo-POlarimeter (HIPPO on the study of magnetic Cataclysmic Variables. Its high-speed capabilities are demonstrated with example observations made of the intermediate polar NY Lup and the polar IGRJ14536-5522.

  17. Spectroscopy of Nine Cataclysmic Variable Stars

    CERN Document Server

    Sheets, H A; Peters, C J; Kapusta, A B; Taylor, C J

    2007-01-01

    We present optical spectroscopy of nine cataclysmic binary stars, mostly dwarf novae, obtained primarily to determine orbital periods Porb. The stars and their periods are LX And, 0.1509743(5) d; CZ Aql, 0.2005(6) d; LU Cam, 0.1499686(4) d; GZ Cnc, 0.0881(4) d; V632 Cyg, 0.06377(8) d; V1006 Cyg, 0.09903(9) d; BF Eri, 0.2708804(4) d; BI Ori, 0.1915(5) d; and FO Per, for which Porb is either 0.1467(4) or 0.1719(5) d. Several of the stars proved to be especially interesting. In BF Eri, we detect the absorption spectrum of a secondary star of spectral type K3 +- 1 subclass, which leads to a distance estimate of approximately 1 kpc. However, BF Eri has a large proper motion (100 mas/yr), and we have a preliminary parallax measurement that confirms the large proper motion and yields only an upper limit for the parallax. BF Eri's space velocity is evidently large, and it appears to belong to the halo population. In CZ Aql, the emission lines have strong wings that move with large velocity amplitude, suggesting a mag...

  18. Searching for Cataclysmic Variables in the J-PLUS Survey

    Science.gov (United States)

    Abril, J.; Ederoclite, A.

    2017-03-01

    Cataclysmic Variables (CVs) are binary systems made of a white dwarf which is accreting mass from a less evolved companion. Depending on the physical properties of the system, the observational characteristics of CVs can be very diverse. Nevertheless, as we learned from projects like the Sloan Digital Sky Survey, CVs occupy the same locus of quasars in color- color diagrams, hence their discovery can be quite challenging. In this paper, we expose how the filter set of the J-PLUS project can help to efficiently separate CVs from other objects (mostly quasars) and even get their type. Through simulations and real data, we explain how accurate the method is and identify the following steps to finally get the first complete unbiased magnitude-limited sample of Cataclysmic Variables to date, a fundamental data set to be able to study the evolution of this type of objects.

  19. Cataclysmic Variables from SDSS III. The Third Year

    CERN Document Server

    Szkody, P; Fraser, O J; Silvestri, N M; Bochanski, J J; Wolfe, M A; Agüeros, M A; Warner, B; Woudt, P; Tramposch, J; Homer, L; Schmidt, G; Knapp, G R; Anderson, S F; Covey, K; Harris, H; Hawley, S; Schneider, D P; Voges, W; Brinkmann, J; Szkody, Paula; Henden, Arne; Fraser, Oliver; Silvestri, Nicole; Bochanski, John; Wolfe, Michael A.; Ag\\"ueros, Marcel; Warner, Brian; Woudt, Patrick; Tramposch, Jonica; Homer, Lee; Schmidt, Gary; Knapp, Gillian R.; Anderson, Scott F.; Covey, Kevin; Harris, Hugh; Hawley, Suzanne; Schneider, Donald P.; Voges, Wolfgang

    2004-01-01

    This paper continues the series that identifies new cataclysmic variables found in the Sloan Digital Sky Survey. We present 36 cataclysmic variables and one possible symbiotic star from Sloan spectra obtained during 2002, of which 34 are new discoveries, 2 are known dwarf novae (BC UMa, KS UMa) and one is a known CV identified from the 2dF survey. The positions, colors and spectra of all 37 systems are presented, along with follow-up spectroscopic/photometric observations of 10 systems. As in the past 2 years of data, the new SDSS systems show a large variety of characteristics based on their inclination and magnetic fields, including 3 eclipsing systems, 4 with prominent He II emission, and 15 systems showing features of the underlying stars.

  20. Realistic MHD Modelling of Cataclysmic Variable Spin-Down

    Science.gov (United States)

    Lascelles, Alex; Garraffo, Cecilia; Drake, Jeremy J.; Cohen, Ofer

    2017-01-01

    The orbital evolution of cataclysmic variables with periods above the "period gap" (>3 hrs) is governed by angular momentum loss via the magnetized wind of the unevolved secondary star. The usual prescription to study such systems takes into account only the magnetic field of the secondary and assumes its field is dipolar. It has been shown that introduction of the white dwarf and its magnetic field can significantly impact the wind’s structure, leading to a change in angular momentum loss rate and evolutionary timescale by an order of magnitude. Furthermore, the complexity of the magnetic field can drastically alter stellar spin-down rates. We explore the effects of orbital separation and magnetic field configuration on mass and angular momentum loss rates through 3-D magnetohydrodynamic simulations. We present the results of a study of cataclysmic variable orbital evolution including these new ingredients.

  1. Hard X-ray properties of magnetic cataclysmic variables

    CERN Document Server

    Scaringi, S; Norton, A J; Knigge, C; Hill, A B; Clark, D J; Dean, A J; McBride, V A; Barlow, E J; Bassani, L; Bazzano, A; Fiocchi, M; Landi, R

    2009-01-01

    Hard X-ray surveys have proven remarkably efficient in detecting intermediate polars and asynchronous polars, two of the rarest type of cataclysmic variable (CV). Here we present a global study of hard X-ray selected intermediate polars and asynchronous polars, focusing particularly on the link between hard X-ray properties and spin/orbital periods. To this end, we first construct a new sample of these objects by cross-correlating candidate sources detected in INTEGRAL/IBIS observations against catalogues of known CVs. We find 23 cataclysmic variable matches, and also present an additional 9 (of which 3 are definite) likely magnetic cataclysmic variables (mCVs) identified by others through optical follow-ups of IBIS detections. We also include in our analysis hard X-ray observations from Swift/BAT and SUZAKU/HXD in order to make our study more complete. We find that most hard X-ray detected mCVs have P_{spin}/P_{orb}<0.1 above the period gap. In this respect we also point out the very low number of detecte...

  2. CCD time-resolved photometry of faint cataclysmic variables. III

    Science.gov (United States)

    Howell, Steve B.; Szkody, Paula; Kreidl, Tobias J.; Mason, Keith O.; Puchnarewicz, E. M.

    1990-01-01

    CCD time-resolved photometry in V, B, and near-IR for 17 faint cataclysmic variables (CVs) is presented and analyzed. The data are obtained at Kitt Peak National Observatory, the Perkins reflector, Lowell Observatory, and the Observatorio del Roque de los Muchachos from April-June 1989. The degree of variability and periodicities for the CVs are examined. It is observed that the variability of most of the stars is consistent with CV class behavior. Orbital periods for five CVs are determined, and three potential eclipsing systems are detected.

  3. Cataclysmic variables in Globular clusters: First results on the analysis of the MOCCA simulations database

    CERN Document Server

    Belloni, Diogo; Askar, Abbas; Hypki, Arkadiusz

    2016-01-01

    In this first investigation of the MOCCA database with respect to cataclysmic variables, we found that for models with Kroupa initial distributions, considering the standard value of the efficiency of the common-envelope phase adopted in BSE, no single cataclysmic variable was formed only via binary stellar evolution, i. e., in order to form them, strong dynamical interactions have to take place. Our results also indicate that the population of cataclysmic variables in globular clusters are, mainly, in the last stage of their evolution and observational selection effects can change drastically the expected number and properties of observed cataclysmic variables.

  4. NSV 1907 - A new eclipsing, nova-like cataclysmic variable

    CERN Document Server

    Hümmerich, Stefan; Hambsch, Franz-Josef; Dubois, Franky; Ashley, Richard; Gänsicke, Boris T; Vanaverbeke, Siegfried; Bernhard, Klaus; Wils, Patrick

    2016-01-01

    NSV 1907, formerly listed as an irregular variable in variability catalogues, was classified as an Algol-type eclipsing binary in the Catalina Surveys Periodic Variable Star Catalogue. We have identified NSV 1907 as an ultraviolet (UV) bright source using measurements from the GALEX space telescope and detected obvious out-of-eclipse variability in archival photometric data from the Catalina Sky Survey, which instigated a closer examination of the object. A spectrum and extensive multicolour photometric observations were acquired, from which we deduce that NSV 1907 is a deeply eclipsing, nova-like cataclysmic variable. Apart from the orbital variations (deep eclipses with a period of P ~ 6.63 hours), changes in mean brightness and irregular short-term variability (flickering) were observed. The presence of a secondary minimum at phase phi ~ 0.5 was established, which indicates a significant contribution of the companion star to the optical flux of the system. We find possible evidence for sinusoidal variation...

  5. Sky surveys of interest for cataclysmic variables

    Science.gov (United States)

    Szkody, Paula

    2016-07-01

    Sky Surveys provide much useful information for finding and understanding catacylsmic variables (CVs). Depending on the length of time the survey runs and the cadence used, the surveys can easily locate novae and dwarf novae based on the amplitude and shape of the light curves. For systems with high inclination or prominent hot spots and periods of hours, some orbital information can be derived from eclipses that are caught or repetitive modulations in the folded light curves. However, in most cases, detailed knowledge of the type of system and its orbital period must come from extended observations at other wavelengths, as most surveys take place in one filter or unfiltered. Currently, we are in the midst of an explosion of recently past, continuing and future plans for sky surveys. The Sloan Digital Sky Survey found about 300 CVs in its Legacy Mode, with small numbers continuing to be added through the extended phases. The CVs were primarily identified through spectroscopic coverage of selected objects from the photometric survey and subsequently found a wide variety of systems (polars, intermediate polars, novalikes, dwarf novae, objects with pulsating white dwarfs) due to spectroscopic differences among these types. The Palomar Transit Factory (PTF), Intermediate PTF and future Zwicky Transient Facilty (ZTF) operate in the same mode of candidate discovery via outbursts followed by spectroscopy for confirmation. The Catalina Real-Time Transient Survey primarily adds dwarf novae that are found from outbursts in the long time span of observations. The Kepler K2 mission operates with a much higher cadence (48-1440 observations/day) but shorter total length (70-80 days) and thus finds CVs through orbital variability as well as those with short outburst intervals. Gaia will provide distances for most of the objects under study, thus locating them in the galaxy. The upcoming Large Synoptic Survey Telescope (LSST) will go much fainter and cover variability on a 10 yr

  6. Followup Observations of SDSS and CRTS Candidate Cataclysmic Variables

    OpenAIRE

    Szkody, Paula; Everett, Mark E.; Howell, Steve B.; Landolt, Arlo U.; Bond, Howard E.; Silva, David R.; Vasquez-Soltero, Stephanie

    2014-01-01

    We present photometry of 11 and spectroscopy of 35 potential cataclysmic variables from the Sloan Digital Sky Survey, the Catalina Real-Time Transient Survey and vsnet-alerts. The photometry results include quasi-periodic oscillations during the decline of V1363 Cyg, nightly accretion changes in the likely Polar (AM Herculis binary) SDSS J1344+20, eclipses in SDSS J2141+05 with an orbital period of 76+/-2 min, and possible eclipses in SDSS J2158+09 at an orbital period near 100 min. Time-reso...

  7. Hunting For Eclipses: High Speed Observations of Cataclysmic Variables

    CERN Document Server

    Hardy, Liam K; Dhillon, Vik S; Littlefair, Stuart P; Bours, Madelon C P; Breedt, Elme; Butterley, Tim; Chakpor, Anurak; Irawati, Puji; Kerry, Paul; Marsh, Tom R; Parsons, Steven G; Savoury, Chris D J; Wilson, Richard W; Woudt, Patrick A

    2016-01-01

    We present new time-resolved photometry of 74 cataclysmic variables (CVs), 47 of which are eclipsing. 13 of these eclipsing systems are newly discovered. For all 47 eclipsing systems we show high cadence (1-20 seconds) light curves obtained with the high-speed cameras ultracam and ultraspec. We provide new or refined ephemerides, and supply mid-eclipse times for all observed eclipses. We assess the potential for light curve modelling of all 47 eclipsing systems to determine their system parameters, finding 20 systems which appear to be suitable for future study.

  8. The Formation of Cataclysmic Variables: The Influence of Nova Eruptions

    Science.gov (United States)

    Nelemans, G.; Siess, L.; Repetto, S.; Toonen, S.; Phinney, E. S.

    2016-01-01

    The theoretical and observed populations of pre-cataclysmic variables are dominated by systems with low-mass white dwarfs (WDs), while the WD masses in cataclysmic variables (CVs) are typically high. In addition, the space density of CVs is found to be significantly lower than in the theoretical models. We investigate the influence of nova outbursts on the formation and initial evolution of CVs. In particular, we calculate the stability of the mass transfer in the case where all of the material accreted on the WD is lost in classical novae and part of the energy to eject the material comes from a common-envelope-like interaction with the companion. In addition, we study the effect of an asymmetry in the mass ejection that may lead to small eccentricities in the orbit. We find that a common-envelope-like ejection significantly decreases the stability of the mass transfer, particularly for low-mass WDs. Similarly, the influence of asymmetric mass loss can be important for short-period systems and even more so for low-mass WDs; however, this influence likely disappears long before the next nova outburst due to orbital circularization. In both cases the mass-transfer rates increase, which may lead to observable (and perhaps already observed) consequences for systems that do survive to become CVs. However, a more detailed investigation of the interaction between nova ejecta and the companion and the evolution of slightly eccentric CVs is needed before definite conclusions can be drawn.

  9. Cataclysmic Variables from SDSS II. The Second Year

    CERN Document Server

    Szkody, P; Silvestri, N M; Henden, A A; Anderson, S F; Frith, W J; Lawton, B; Owens, E; Raymond, S; Schmidt, G; Wolfe, M; Bochanski, J J; Covey, K; Harris, H; Hawley, S; Knapp, G R; Margon, B; Voges, W; Walkowicz, L; Brinkmann, J; Lamb, D Q; Anderson, Scott F.; Bochanski, John; Covey, Kevin; Fraser, Oliver; Frith, James; Harris, Hugh; Hawley, Suzanne; Henden, Arne; Knapp, Gillian R.; Lawton, Brandon; Margon, Bruce; Owens, Ethan; Raymond, Sean; Schmidt, Gary; Silvestri, Nicole; Szkody, Paula; Voges, Wolfgang; Walkowicz, Lucianne; Wolfe, Michael

    2003-01-01

    The first full year of operation following the commissioning year of the Sloan Digital Sky Survey has revealed a wide variety of newly discovered cataclysmic variables. We show the SDSS spectra of forty-two cataclysmic variables observed in 2002, of which thirty-five are new classifications, four are known dwarf novae (CT Hya, RZ Leo, T Leo and BZ UMa), one is a known CV identified from a previous quasar survey (Aqr1) and two are known ROSAT or FIRST discovered CVs (RX J09445+0357, FIRST J102347.6+003841). The SDSS positions, colors and spectra of all forty-two systems are presented. In addition, the results of follow-up studies of several of these objects identify the orbital periods, velocity curves and polarization that provide the system geometry and accretion properties. While most of the SDSS discovered systems are faint (>18th mag) with low accretion rates (as implied from their spectral characteristics), there are also a few bright objects which may have escaped previous surveys due to changes in the ...

  10. The Magnetic Cataclysmic Variable LSQ1725-64

    CERN Document Server

    Fuchs, J T; Dennihy, E; O'Donoghue, D; Clemens, J C; Reichart, D E; Moore, J P; LaCluyze, A P; Haislip, J B; Ivarsen, K V

    2016-01-01

    We present new photometry and spectroscopy of the 94m eclipsing binary LSQ1725-64 that provide insight into the fundamental parameters and evolutionary state of this system. We confirm that LSQ1725-64 is a magnetic cataclysmic variable whose white dwarf has a surface-averaged magnetic field strength of $12.5 \\pm 0.5$ MG measured from Zeeman splitting. The spectral type and colour of the secondary, as well as the eclipse length, are consistent with other secondaries that have not yet evolved through the period minimum expected for cataclysmic variables. We observe two different states of mass transfer and measure the transition between the two to occur over about 45 orbital cycles. In the low state, we observe photometric variations that we hypothesize to arise predominantly from two previously heated magnetic poles of the white dwarf. Our precise eclipse measurements allow us to determine binary parameters of LSQ1725-64 and we find it contains a high mass ($0.97 \\pm 0.03\\ M_{\\odot}$) white dwarf if we assume ...

  11. On the White Dwarf Mass Problem of Cataclysmic Variables

    CERN Document Server

    Liu, Wei-Min

    2016-01-01

    Recent observations show that the white dwarfs (WDs) in cataclysmic Variables (CVs) have an average mass significantly higher than isolated WDs and WDs in post-common envelope binaries (PCEBs), which are thought to the progenitors of CVs. This suggests that either the WDs have grown in mass during the PCEB/CV evolution or the binaries with low-mass WDs are unable to evolve to be CVs. In this paper, we calculate the evolution of accreting WD binaries with updated hydrogen accumulation efficiency and angular momentum loss prescriptions. We show that thermal timescale mass transfer is not effective in changing the average WD mass distribution. The WD mass discrepancy is most likely related to unstable mass transfer in WD binaries in which an efficient mechanism of angular momentum loss is required.

  12. Cataclysmic variables in the SUPERBLINK proper motion survey

    Energy Technology Data Exchange (ETDEWEB)

    Skinner, Julie N.; Thorstensen, John R. [Department of Physics and Astronomy, 6127 Wilder Laboratory, Dartmouth College, Hanover, NH 03755-3528 (United States); Lépine, Sébastien, E-mail: jns@dartmouth.edu [Department of Physics and Astronomy, Georgia State University, 25 Park Place NE, Atlanta, GA 30303 (United States)

    2014-12-01

    We have discovered a new high proper motion cataclysmic variable (CV) in the SUPERBLINK proper motion survey, which is sensitive to stars with proper motions greater than 40 mas yr{sup −1}. This CV was selected for follow-up observations as part of a larger search for CVs selected based on proper motions and their near-UV−V and V−K{sub s} colors. We present spectroscopic observations from the 2.4 m Hiltner Telescope at MDM Observatory. The new CV's orbital period is near 96 minutes, its spectrum shows the double-peaked Balmer emission lines characteristic of quiescent dwarf novae, and its V magnitude is near 18.2. Additionally, we present a full list of known CVs in the SUPERBLINK catalog.

  13. Cataclysmic Variables in the SUPERBLINK Proper Motion Survey

    CERN Document Server

    Skinner, Julie N; Lépine, Sébastien

    2014-01-01

    We have discovered a new high proper motion cataclysmic variable (CV) in the SUPERBLINK proper motion survey, which is sensitive to stars with proper motions greater than 40 mas/yr. This CV was selected for follow-up observations as part of a larger search for CVs selected based on proper motions and their NUV-V and V-K$_{s}$ colors. We present spectroscopic observations from the 2.4m Hiltner Telescope at MDM Observatory. The new CV's orbital period is near 96 minutes, its spectrum shows the double-peaked Balmer emission lines characteristic of quiescent dwarf novae, and its V magnitude is near 18.2. Additionally, we present a full list of known CVs in the SUPERBLINK catalog.

  14. Hunting for eclipses: high-speed observations of cataclysmic variables

    Science.gov (United States)

    Hardy, L. K.; McAllister, M. J.; Dhillon, V. S.; Littlefair, S. P.; Bours, M. C. P.; Breedt, E.; Butterley, T.; Chakpor, A.; Irawati, P.; Kerry, P.; Marsh, T. R.; Parsons, S. G.; Savoury, C. D. J.; Wilson, R. W.; Woudt, P. A.

    2017-03-01

    We present new time-resolved photometry of 74 cataclysmic variables (CVs), 47 of which are eclipsing. Thirteen of these eclipsing systems are newly discovered. For all 47 eclipsing systems, we show high cadence (1-20 s) light curves obtained with the high-speed cameras ULTRACAM and ULTRASPEC. We provide new or refined ephemerides, and supply mid-eclipse times for all observed eclipses. We assess the potential for light-curve modelling of all 47 eclipsing systems to determine their system parameters, finding 20 systems that appear to be suitable for future study. Systems of particular interest include V713 Cep, in which we observed a temporary switching-off of accretion; and ASASSN-14mv and CSS111019:233313-155744, which both have orbital periods well below the CV period minimum. The short orbital periods and light-curve shapes suggest that they may be double degenerate (AM CVn) systems or CVs with evolved donor stars.

  15. NSV 1907 - A new eclipsing, nova-like cataclysmic variable

    Science.gov (United States)

    Hümmerich, Stefan; Gröbel, Rainer; Hambsch, Franz-Josef; Dubois, Franky; Ashley, Richard; Gänsicke, Boris T.; Vanaverbeke, Siegfried; Bernhard, Klaus; Wils, Patrick

    2017-01-01

    NSV 1907, formerly listed as an irregular variable in variability catalogues, was classified as an Algol-type eclipsing binary in the Catalina Surveys Periodic Variable Star Catalogue. We have identified NSV 1907 as an ultraviolet (UV) bright source using measurements from the GALEX space telescope and detected obvious out-of-eclipse variability in archival photometric data from the Catalina Sky Survey, which instigated a closer examination of the object. A spectrum and extensive multicolour photometric observations were acquired, from which we deduce that NSV 1907 is a deeply eclipsing, nova-like cataclysmic variable. Apart from the orbital variations (deep eclipses with a period of P ≈ 6.63 hours), changes in mean brightness and irregular short-term variability (flickering) were observed. The presence of a secondary minimum at phase φ ≈ 0.5 was established, which indicates a significant contribution of the companion star to the optical flux of the system. We find possible evidence for sinusoidal variations with a period of P ≈ 4.2 d, which we interpret as the nodal precession period of the accretion disc. No outbursts or VY Scl-like drops in brightness were detected either by the CSS or during our photometric monitoring. Because of its spectral characteristics and the observed variability pattern, we propose NSV 1907 as a new moderately bright long-period SW Sextantis star. Further photometric and spectroscopic observations are encouraged.

  16. Photometry of some neglected bright cataclysmic variables and candidates

    Science.gov (United States)

    Bruch, Albert

    2017-04-01

    As part of an effort to better characterize bright cataclysmic variables (CVs) which have received little attention in the past light curves of four confirmed systems (CZ Aql, BO Cet, V380 Oph and EF Tuc) and one candidate (Lib 3) are analyzed. For none of these stars time resolved photometry has been published previously. While no variability was found in the case of Lib 3, which thus cannot be confirmed as a CV, the light curves of all other targets are dominated by strong flickering. Modulations on hourly time scales superimposed on the flickering can probably be related to orbital variations in BO Cet and V380 Oph, but not in CZ Aql and EF Tuc. Variations on the time scale of 10 min in CZ Aql, while not yet constituting convincing evidence, together with previous suspicions of a magnetically channeled accretion flow may point at an intermediate polar nature of this star. Some properties of the flickering are quantified in an effort to enlarge the data base for future comparative flickering studies in CVs and to refine the classification of the target stars.

  17. Photometry of some neglected bright cataclysmic variables and candidates

    CERN Document Server

    Bruch, Albert

    2016-01-01

    As part of an effort to better characterize bright cataclysmic variables (CVs) which have received little attention in the past light curves of four confirmed systems (CZ Aql, BO Cet, V380 Oph and EF Tuc) and one candidate (Lib 3) are analyzed. For none of these stars time resolved photometry has been published previously. While no variability was found in the case of Lib 3, which thus cannot be confirmed as a CV, the light curves of all other targets are dominated by strong flickering. Modulations on hourly time scales superimposed on the flickering can probably be related to orbital variations in BO Cet and V380 Oph, but not in CZ Aql and EF Tuc. Variations on the time scale of 10 minutes in CZ Aql, while not yet constituting convincing evidence, together with previous suspicions of a magnetically channeled accretion flow may point at an intermediate polar nature of this star. Some properties of the flickering are quantified in an effort to enlarge the data base for future comparative flickering studies in ...

  18. Excess mid-IR emission in Cataclysmic Variables

    CERN Document Server

    Dubus, G; Kern, B; Taam, R E; Spruit, H C

    2004-01-01

    We present a search for excess mid-IR emission due to circumbinary material in the orbital plane of cataclysmic variables (CVs). Our motivation stems from the fact that the strong braking exerted by a circumbinary (CB) disc on the binary system could explain several puzzles in our current understanding of CV evolution. Since theoretical estimates predict that the emission from a CB disc can dominate the spectral energy distribution (SED) of the system at wavelengths > 5 microns, we obtained simultaneous visible to mid-IR SEDs for eight systems. We report detections of SS Cyg at 11.7 microns and AE Aqr at 17.6 microns, both in excess of the contribution from the secondary star. In AE Aqr, the IR likely originates from synchrotron-emitting clouds propelled by the white dwarf. In SS Cyg, we argue that the observed mid-IR variability is difficult to reconcile with simple models of CB discs and we consider free-free emission from a wind. In the other systems, our mid-IR upper limits place strong constraints on the...

  19. AE Aquarii represents a new subclass of Cataclysmic Variables

    CERN Document Server

    Ikhsanov, N R

    2012-01-01

    We analyze properties of the unique nova-like star AE Aquarii identified with a close binary system containing a red dwarf and a very fast rotating magnetized white dwarf. It cannot be assigned to any of the three commonly adopted sub-classes of Cataclysmic Variables: Polars, Intermediate Polars, and Accreting non-magnetized White Dwarfs. Our study has shown that the white dwarf in AE Aqr is in the ejector state and its dipole magnetic moment is $\\mu ~ 1.5 \\times 10^{34} G cm^3$. It switched into this state due to intensive mass exchange between the system components during a previous epoch. A high rate of disk accretion onto the white dwarf surface resulted in temporary screening of its magnetic field and spin-up of the white dwarf to its present spin period. Transition of the white dwarf to the ejector state had occurred at a final stage of the spin-up epoch as its magnetic field emerged from the accreted plasma due to diffusion. In the frame of this scenario AE Aqr represents a missing link in the chain of...

  20. Exploring inside-out Doppler tomography: magnetic cataclysmic variables

    CERN Document Server

    Kotze, Enrico J; McBride, Vanessa A

    2016-01-01

    We present the results of applying our inside-out velocity projection and flux modulation mapping techniques to the Doppler tomography of magnetic cataclysmic variables. The inside-out tomogram is constructed by directly projecting phase-resolved spectra onto the inside-out framework. In addition, our flux modulation mapping technique extracts any information related to the modulation of the line flux by utilising consecutive half-phase tomograms. We apply this to both the standard and the inside-out techniques. Our test cases, the polars HU Aqr and V834 Cen, and the intermediate polar PQ Gem, were chosen because of their known accretion characteristics, namely ballistic, magnetic and curtain dominated accretion, respectively. In all three cases the inside-out tomogram better exposes low-velocity emission details which are overly compacted in the standard tomogram. This is especially apparent for the mid-inclination V834 Cen where the almost blob-like blended lower velocity emission in the standard tomogram i...

  1. ULTRACAM photometry of the eclipsing cataclysmic variable OU Vir

    CERN Document Server

    Feline, W J; Marsh, T R; Stevenson, M J; Watson, C A; Brinkworth, C S

    2004-01-01

    We present high-speed, three-colour photometry of the faint eclipsing cataclysmic variable OU Vir. For the first time in OU Vir, separate eclipses of the white dwarf and bright spot have been observed. We use timings of these eclipses to derive a purely photometric model of the system, obtaining a mass ratio of q = 0.175 +/- 0.025, an inclination of i = 79.2 +/- 0.7 degrees and a disc radius of Rd/a = 0.2315 +/- 0.0150. We separate the white dwarf eclipse from the lightcurve and, by fitting a blackbody spectrum to its flux in each passband, obtain a white dwarf temperature of T = 13900 +/- 600 K and a distance of D = 51 +/- 17 pc. Assuming that the primary obeys the Nauenberg (1972) mass-radius relation for white dwarfs and allowing for temperature effects, we also find a primary mass Mw/Msun = 0.89 +/- 0.20, primary radius Rw/Rsun = 0.0097 +/- 0.0031 and orbital separation a/Rsun = 0.74 +/- 0.05.

  2. A possible giant planet orbiting the cataclysmic variable LX Ser

    CERN Document Server

    Li, K; Zhou, J -L; Wu, D -H; Guo, D -F; Jiang, Y -G; Gao, D -Y; Chen, X; Wang, X -Y

    2016-01-01

    LX Ser is a deeply eclipsing cataclysmic variable with an orbital period of $0.^d 1584325$. Sixty two new eclipse times were determined by our observations and the AAVSO International Data base. Combining all available eclipse times, we analyzed the O-C behavior of LX Ser. We found that the O-C diagram of LX Ser shows a sinusoidal oscillation with a period of 22.8 yr and an amplitude of 0.00035 days. Two mechanisms (i.e., the Applegate mechanism and the light travel time effect) are applied to explain the cyclic modulation. We found that the Applegate mechanism is difficult to explain the cyclic oscillation in the orbital period. Therefore, the cyclic period change is most likely to be caused by the light travel time effect due to the presence of a third body. The mass of the tertiary component was determined to be $M_3\\sim7.5 M_{Jup}$. We supposed that the tertiary companion is plausible a giant planet. The stability of the giant planet was checked, and we found that the multiple system is stable.

  3. The formation of Cataclysmic Variables: the influence of nova eruptions

    CERN Document Server

    Nelemans, G; Repetto, S; Toonen, S; Phinney, E S

    2015-01-01

    The theoretical and observed populations of pre-cataclysmic variables (pre-CVs) are dominated by systems with low-mass white dwarfs (WDs), while the WD masses in CVs are typically high. In addition, the space density of CVs is found to be significantly lower than theoretical models. We investigate the influence of nova outbursts on the formation and (initial) evolution of CVs. In particular, we calculate the stability of the mass transfer in case all the material accreted on the WD is lost in classical novae, and part of the energy to eject the material comes from a common-envelope like interaction with the companion. In addition, we study the effect of an asymmetry in the mass ejection, that may lead to small eccentricities in the orbit. We find that a common-envelope like ejection significantly decreases the stability of the mass transfer, in particular for low-mass WD. Similarly, the influence of asymmetric mass loss can be important for short-period systems and even more so for low-mass WD, but likely dis...

  4. Characterization of new hard X-ray Cataclysmic Variables

    CERN Document Server

    Bernardini, F; Falanga, M; Mukai, K; Matt, G; Bonnet-Bidaud, J -M; Masetti, N; Mouchet, M

    2012-01-01

    We aim at characterizing a sample of 9 new hard X-ray selected Cataclysmic Variable (CVs), to unambiguously identify them as magnetic systems of the Intermediate Polar (IP) type. We performed timing and spectral analysis by using X-ray, and simultaneous UV and optical data collected by XMM-Newton, complemented with hard X-ray data provided by INTEGRAL and Swift. The pulse arrival time were used to estimate the orbital periods. The X-ray spectra were fitted using composite models consisting of different absorbing columns and emission components. Strong X-ray pulses at the White Dwarf (WD) spin period are detected and found to decrease with energy. Most sources are spin-dominated systems in the X-rays, though four are beat dominated at optical wavelengths. We estimated the orbital period in all system (except for IGR J16500-3307), providing the first estimate for IGR J08390-4833, IGR J18308-1232, and IGR J18173-2509. All X-ray spectra are multi-temperature. V2069 Cyg and RX J0636+3535 posses a soft X-ray optica...

  5. IGR J18293-1213 is an eclipsing Cataclysmic Variable

    CERN Document Server

    Clavel, Maïca; Bodaghee, A; Chiu, J -L; Fornasini, F M; Hong, J; Krivonos, R; Ponti, G; Rahoui, F; Stern, D

    2016-01-01

    Studying the population of faint hard X-ray sources along the plane of the Galaxy is challenging because of high-extinction and crowding, which make the identification of individual sources more difficult. IGR J18293-1213 is part of the population of persistent sources which have been discovered by the INTEGRAL satellite. We report on NuSTAR and Swift/XRT observations of this source, performed on 2015 September 11. We detected three eclipsing intervals in the NuSTAR light curve, allowing us to constrain the duration of these eclipses, $\\Delta t = 30.8^{+6.3}_{-0.0}$ min, and the orbital period of the system, $T = 6.92\\pm0.01$ hr. Even though we only report an upper limit on the amplitude of a putative spin modulation, the orbital period and the hard thermal Bremsstrahlung spectrum of IGR J18293-1213 provide strong evidence that this source is a magnetic Cataclysmic Variable (CV). Our NuSTAR and Swift/XRT joint spectral analysis places strong constraints on the white dwarf mass $M_{\\rm wd} = 0.78^{+0.10}_{-0.0...

  6. Detached cataclysmic variables are crossing the orbital period gap

    CERN Document Server

    Zorotovic, Monica; Parsons, Steven G; Gänsicke, Boris T; Hardy, Adam; Agurto-Gangas, Carolina; Gómez-Morán, Ada Nebot; Rebassa-Mansergas, Alberto; Schwope, Axel D

    2016-01-01

    A central hypothesis in the theory of cataclysmic variable (CV) evolution is the need to explain the observed lack of accreting systems in the ~2-3 h orbital period range, known as the period gap. The standard model, disrupted magnetic braking (DMB), reproduces the gap by postulating that CVs transform into inconspicuous detached white dwarf (WD) plus main sequence (MS) systems, which no longer resemble CVs. However, observational evidence for this standard model is currently indirect and thus this scenario has attracted some criticism throughout the last decades. Here we perform a simple but exceptionally strong test of the existence of detached CVs (dCVs). If the theory is correct dCVs should produce a peak in the orbital period distribution of detached close binaries consisting of a WD and an M4-M6 secondary star. We measured six new periods which brings the sample of such binaries with known periods below 10 h to 52 systems. An increase of systems in the ~2-3 h orbital period range is observed. Comparing ...

  7. A possible giant planet orbiting the cataclysmic variable LX Ser

    Science.gov (United States)

    Li, Kai; Hu, Shaoming; Zhou, Jilin; Wu, Donghong; Guo, Difu; Jiang, Yunguo; Gao, Dongyang; Chen, Xu; Wang, Xianyu

    2017-02-01

    LX Ser is a deeply eclipsing cataclysmic variable with an orbital period of 0.1584325 d. 62 new eclipse times were determined by our observations and the AAVSO International Data base. Combining all available eclipse times, we analyzed the O - C behavior of LX Ser. We found that the O - C diagram of LX Ser shows a sinusoidal oscillation with a period of 22.8 yr and an amplitude of 0.00035 d. Two mechanisms (i.e., the Applegate mechanism and the light-travel time effect) are applied to explain the cyclic modulation. We found that it is difficult to apply the Applegate mechanism to explain the cyclic oscillation in the orbital period. Therefore, the cyclic period change is most likely to be caused by the light-travel time effect due to the presence of a third body. The mass of the tertiary component was determined to be M3 ∼ 7.5 MJup. We supposed that the tertiary companion is plausibly a giant planet. The stability of the giant planet was checked, and we found that the multiple system is stable.

  8. Dynamical formation of cataclysmic variables in globular clusters

    Science.gov (United States)

    Hong, Jongsuk; Vesperini, Enrico; Belloni, Diogo; Giersz, Mirek

    2017-01-01

    The formation and evolution of X-ray sources in globular clusters is likely to be affected by the cluster internal dynamics and the stellar interactions in the cluster dense environment. Several observational studies have revealed a correlation between the number of X-ray sources and the stellar encounter rate, and provided evidence of the role of dynamics in the formation of X-ray binaries. We have performed a survey of Monte Carlo simulations aimed at exploring the connection between the dynamics and formation of cataclysmic variables (CVs) and the origin of the observed correlation between the number of these objects, Ncv, and the stellar encounter rate, Γ. The results of our simulations show a correlation between Ncv and Γ, as found in observational data, illustrate the essential role played by the dynamics, and shed light on the dynamical history behind this correlation. CVs in our simulations are more centrally concentrated than single stars with masses close to those of turn-off stars, although this trend is stronger for CVs formed from primordial binaries undergoing exchange encounters, which include a population of more massive CVs absent in the group of CVs formed from binaries not suffering any component exchange.

  9. Dynamical Formation of Cataclysmic Variables in Globular Clusters

    CERN Document Server

    Hong, Jongsuk; Belloni, Diogo; Giersz, Mirek

    2016-01-01

    The formation and evolution of X-ray sources in globular clusters is likely to be affected by the cluster internal dynamics and the stellar interactions in the cluster dense environment.Several observational studies have revealed a correlation between the number of X-ray sources and the stellar encounter rate and provided evidence of the role of dynamics in the formation of X-ray binaries. We have performed a survey of Monte-Carlo simulations aimed at exploring the connection between the dynamics and formation of cataclysmic variables (CVs) and the origin of the observed correlation between the number of these objects, $N_{\\rm cv}$, and the stellar encounter rate, $\\Gamma$.The results of our simulations show a correlation between $N_{\\rm cv}$ and $\\Gamma$ as found in observational data, illustrate the essential role played by dynamics, and shed light on the dynamical history behind this correlation. CVs in our simulations are more centrally concentrated than single stars with masses close to those of turn-off...

  10. New Southern Cataclysmic Variables: Discoveries from MASTER-SAAO

    Science.gov (United States)

    Buckley, D. A. H.; Potter, S. B.; Kniazev, A.; Lipunov, V.; Gorbovskoy, E.; Tiurina, N.

    2017-03-01

    In this paper we report on new cataclysmic variables (CVs) discovered by the first local optical transient detection system established at the SAAO Sutherland station, namely MASTER-SAAO. The characteristics of the MASTER-SAAO system are described and the parameters of the survey compared to the Catalina Real Time Survey (CRTS). To date MASTER-SAAO has discovered over 200 (non-Solar System) optical transients with about 75% of these being likely new CVs, most being dwarf novae (DNe). Approximately 50% of the DNe have outburst amplitudes in excess of 4 magnitudes, with some extreme amplitude (> 7 mag), probable WZ Sge systems. The MASTER-SAAO detection limit of B = 19–20 is comparable to the ˜20 magnitude limit of the CRTS (depending on CV colour). Based on the CV detection statistics of CRTS, we believe that MASTER-SAAO is detecting essentially the same CV population as CRTS, for a detection outburst amplitude threshold >2.2 magnitudes. We also present results of the initial follow-up program on CVs discovered by MASTER, including dwarf novae, a bright new VY Scl system and a new eclipsing polar.

  11. Nova-like cataclysmic variables in the infrared

    Energy Technology Data Exchange (ETDEWEB)

    Hoard, D. W. [Eureka Scientific, Inc., Oakland, CA (United States); Long, Knox S. [Space Telescope Science Institute, Baltimore, MD (United States); Howell, Steve B. [NASA Ames Research Center, Moffett Field, CA (United States); Wachter, Stefanie [Max Planck Institut für Astronomie, D-69117 Heidelberg (Germany); Brinkworth, Carolyn S. [Spitzer Science Center, California Institute of Technology, Pasadena, CA (United States); Knigge, Christian [Physics and Astronomy, University of Southampton, Southampton (United Kingdom); Drew, J. E. [Centre for Astrophysics Research, Science and Technology Research Institute, University of Hertfordshire, Hatfield (United Kingdom); Szkody, Paula [Department of Astronomy, University of Washington, Seattle, WA (United States); Kafka, S. [Carnegie Institution of Washington, Department of Terrestrial Magnetism, Washington, DC (United States); Belle, Kunegunda [Los Alamos National Laboratory, Los Alamos, NM (United States); Ciardi, David R. [NASA Exoplanet Science Institute, California Institute of Technology, Pasadena, CA (United States); Froning, Cynthia S. [Center for Astrophysics and Space Astronomy, Department of Astrophysical and Planetary Sciences, University of Colorado, Boulder, CO (United States); Van Belle, Gerard T. [Lowell Observatory, Flagstaff, AZ (United States); Pretorius, M. L., E-mail: hoard@mpia.de [Department of Physics, University of Oxford, Oxford (United Kingdom)

    2014-05-01

    Nova-like (NL) cataclysmic variables have persistently high mass transfer rates and prominent steady state accretion disks. We present an analysis of infrared observations of 12 NLs obtained from the Two Micron All Sky Survey, the Spitzer Space Telescope, and the Wide-field Infrared Survey Explorer All Sky Survey. The presence of an infrared excess at λ ≳ 3-5 μm over the expectation of a theoretical steady state accretion disk is ubiquitous in our sample. The strength of the infrared excess is not correlated with orbital period, but shows a statistically significant correlation (but shallow trend) with system inclination that might be partially (but not completely) linked to the increasing view of the cooler outer accretion disk and disk rim at higher inclinations. We discuss the possible origin of the infrared excess in terms of emission from bremsstrahlung or circumbinary dust, with either mechanism facilitated by the mass outflows (e.g., disk wind/corona, accretion stream overflow, and so on) present in NLs. Our comparison of the relative advantages and disadvantages of either mechanism for explaining the observations suggests that the situation is rather ambiguous, largely circumstantial, and in need of stricter observational constraints.

  12. A spectroscopic search for faint secondaries in cataclysmic variables

    CERN Document Server

    Putte, D V; Hawkins, N A; Martin, J S; Smith, Robert Connon

    2003-01-01

    The secondary in cataclysmic variables (CV's) is usually detected by cross-correlation of the CV spectrum with that of a K or M dwarf template, to produce a radial velocity curve. Although this method has demonstrated its power, it has its limits in the case of noisy spectra, such as are found when the secondary is faint. A method of co-adding spectra, called skew mapping, has been proposed in the past. Gradually, examples of its application are being published. Nonetheless, so far no journal article has described the technique in detail. To answer this need, this paper explores in detail the capabilities of skew mapping when determining the amplitude of the radial velocity for faint secondaries. It demonstrates the method's power over techniques that are more conventional, when the signal-to-noise (s/n) ratio is poor. The paper suggests an approach to assessing the quality of results. This leads in the case of the investigated objects to a first tier of results, where we find K2=127+-23 km/s for SY Cnc, K2=1...

  13. On the late spectral types of cataclysmic variable secondaries

    CERN Document Server

    Baraffe, I

    2000-01-01

    We investigate why the spectral type of most cataclysmic variable (CV) secondaries is significantly later than that of a ZAMS star with the same mean density. Using improved stellar input physics, tested against observations of low-mass stars at the bottom of the main sequence, we calculate the secular evolution of CVs with low-mass donors. We consider sequences with different mass transfer rates and with a different degree of nuclear evolution of the donor prior to mass transfer. Systems near the upper edge of the gap ($P \\sim 3 - 6$ h) can be reproduced by models with a wide range of mass transfer rates from $1.5 \\times 10^{-9} \\msolyr$ to $10^{-8} \\msolyr$. Evolutionary sequences with a small transfer rate and donors that are substantially evolved off the ZAMS (central hydrogen content $0.05-0.5$) reproduce CVs with late spectral types above $P \\simgr$ 6 h. Systems with the most discrepant (late) spectral type should have the smallest donor mass at any given $P$. Consistency with the period gap suggests th...

  14. Cataclysmic variables and related objects; Proceedings of the Seventy-second Colloquium, Haifa, Israel, August 9-13, 1982

    Science.gov (United States)

    Livio, M.; Shaviv, G.

    The periods of cataclysmic variable stars are considered along with photometric and spectroscopic observations of the cataclysmic variable AC Cancri, recent spectroscopy of X-ray sources and systems related to cataclysmic variables, orbital solutions for WZ Sagittae during quiescence, spectra of symbiotic stars, and the formation of optical CNO emission lines in cataclysmic variables. Attention is given to infrared spectra of nova dust shells, evolutionary models for SNI progenitor stars, the physical conditions inside white dwarfs and type I supernovae, the energy distribution of hard X-ray emitting cataclysmic variables, time dependence in accretion onto magnetic white dwarfs, polarized radiation from AM Herculis stars, and radio emission and synchronization. Other topics discussed are related to X-ray emission from cataclysmic variables, mass loss associated with X-ray bursts of neutron stars, and fast oscillations in variable X-ray sources and X-ray bursters. For individual items see A84-35927 to A84-35954

  15. Characterization of New Hard X-ray Cataclysmic Variables

    Science.gov (United States)

    Bernardini, F.; deMartino, D.; Falanga, M.; Mukai, K.; Matt, G.; Bonnet-Bidaud, J.-M.; Masetti, N.; Mouchet, M.

    2012-01-01

    Aims. We aim at characterizing a sample of nine new hard X-ray selected Cataclysmic Variable (CVs), to unambiguously identify them as magnetic systems of the Intermediate Polar (IP) type. Methods. We performed detailed timing and spectral analysis by using X-ray, and simultaneous UV and optical data collected by XMM-Newton, complemented with hard X-ray data provided by INTEGRAL and Swift. The pulse arrival time were used to estimate the orbital periods. The broad band X-ray spectra were fitted using composite models consisting of different absorbing columns and emission components. Results. Strong X-ray pulses at the White Dwarf (WD) spin period are detected and found to decrease with energy. Most sources are spin-dominated systems in the X-rays, though four are beat dominated at optical wavelengths. We estimated the orbital period in all system (except for IGR J16500-3307), providing the first estimate for IGRJ08390-4833, IGRJ18308-1232, and IGR J18173-2509. All X-ray spectra are multi-temperature. V2069 Cyg and RX J0636+3535 poses a soft X-ray optically thick component at kT approx. 80 eV. An intense K (sub alpha) Fe line at 6.4 keV is detected in all sources. An absorption edge at 0.76 keV from OVII is detected in IGR J08390-4833. The WD masses and lower limits to the accretion rates are also estimated. Conclusions. We found all sources to be IPs. IGR J08390-4833, V2069 Cyg, and IGR J16500-3307 are pure disc accretors, while IGR J18308-1232, IGR J1509-6649, IGR J17195-4100, and RX J0636+3535 display a disc-overflow accretion mode. All sources show a temperature gradient in the post-shock regions and a highly absorbed emission from material located in the pre-shock flow which is also responsible for the X-ray pulsations. Reflection at the WD surface is likely the origin of the fluorescent iron line. There is an increasing evidence for the presence of a warm absorber in IPs, a feature that needs future exploration. The addition of two systems to the subgroup of

  16. Cataclysmic Variables below the Period Gap: Mass Determinations of 14 Eclipsing Systems

    CERN Document Server

    Savoury, C D J; Dhillon, V S; Marsh, T R; Gaensicke, B T; Copperwheat, C M; Kerry, P; Hickman, R D G; Parsons, S G

    2011-01-01

    We present high-speed, three-colour photometry of the eclipsing cataclysmic variables CTCV 1300, CTCV 2354 and SDSS 1152. All three systems are below the observed "period gap" for cataclysmic variables. For each system we determine the system parameters by fitting a parameterised model to the observed eclipse light curve by chi-squared minimisation. We also present an updated analysis of all other eclipsing systems previously analysed by our group. New donor masses are generally between 1 and 2 sigma of those originally published, with the exception of SDSS 1502 and DV UMa. We note that the donor mass of SDSS 1501 has been revised upwards by 0.024Msun. This system was previously identified as having evolved passed the minimum orbital period for cataclysmic variables, but the new mass determination suggests otherwise. Our new analysis confirms that SDSS 1035 and SDSS 1433 have evolved past the period minimum for cataclysmic variables, corroborating our earlier studies. We find that the radii of donor stars are...

  17. Studies of an x ray selected sample of cataclysmic variables. Ph.D. Thesis

    Science.gov (United States)

    Silber, Andrew D.

    1986-01-01

    Just prior to the thesis research, an all-sky survey in hard x rays with the HEAO-1 satellite and further observations in the optical resulted in a catalog of about 700 x-ray sources with known optical counterparts. This sample includes 43 cataclysmic variables, which are binaries consisting of a detached white-dwarf and a Roche lobe filling companion star. This thesis consists of studies of the x-ray selected sample of catalcysmic variables.

  18. Angular momentum transport in the magnetospheres of cataclysmic variable accretion discs

    Energy Technology Data Exchange (ETDEWEB)

    Koen, C.

    1986-12-01

    The theory of stellar magnetic braking is applied to circumstellar discs. The focus is concentrated on cataclysmic variable stars but results apply to any disc in which the rotational velocity is Keplerian. Calculations are done for two magnetic field configurations and numerical results given for a range of physical parameter values. It is found that magnetic processes could be efficient in the removal of angular momentum from such systems.

  19. [Data mining for cataclysmic variables candidates in SDSS-DR8].

    Science.gov (United States)

    Jiang, Bin; Pan, Jing-Chang; Wang, Wei

    2013-02-01

    An automatic and efficient method for cataclysmic variables candidates is presented in this paper. The nonlinear locally linear embedding-LLE method is applied in the newly released SDSS-DR8 spectra. Spectra are dimension-reduced by LLE and classified by artificial neural network. The greatly reduced final candidates can be identified manually. 6 new CVs candidates were found in the experiment, and the compare between LLE with PCA shows the feasibility of nonlinear method in data mining in astronomical data.

  20. Observations of the Cataclysmic Variable 1 RXPJ113123+4322.5

    Science.gov (United States)

    Holtgrewe, Kirk S.; Durig, Douglas T.

    We observed the cataclysmic variable star l RXPJ113123+4322.5 while it was undergoing its recent outburst. We collected data using R and V filters, alternating the filters every two minutes. We obtained two to three hour-long data sets on two different nights. The light curve was analyzed using Mathematica. The period determined was near 95 minutes and there was also some indication of a lower amplitude, higher frequency variation.

  1. Exploratory Spectroscopy of Magnetic Cataclysmic Variables Candidates and Other Variable Objects

    CERN Document Server

    Oliveira, A S; Cieslinski, D; Jablonski, F J; Silva, K M G; Almeida, L A; Rodriguez-Ardila, A; Palhares, M S

    2016-01-01

    The increasing number of synoptic surveys made by small robotic telescopes, as the photometric Catalina Real-Time Transient Survey (CRTS), represents a unique opportunity for the discovery of new variable objects, improving the samples of many classes of variables. Our goal is the discovery of new magnetic Cataclysmic Variables (mCVs). They are rare objects, which probe interesting accretion scenarios controlled by the white-dwarf magnetic field. We performed an optical spectroscopic survey to search for signatures of magnetic accretion on 47 variable objects selected mostly from CRTS. Our sample includes 13 polar strong candidates, from which 5 are new discoveries. Accretion disks seem to be present in other 19 objects. One is a previously known probable intermediate polar. We suggest 8 other objects could also be of this class. In particular, 7 of them have spectra consistent with short-period intermediate polars. We suggest one object is a novalike of the VY~Scl class. We also caught one dwarf nova in erup...

  2. MOCCA-SURVEY Database I. Accreting White Dwarf Binary Systems in Globular Clusters I. Cataclysmic Variables -- present-day population

    CERN Document Server

    Belloni, Diogo T; Askar, Abbas; Leigh, Nathan; Hypki, Arkadiusz

    2016-01-01

    In this paper, which is the first in a series of papers associated with cataclysmic variables and related objects, we introduce the CATUABA code, a numerical machinery written for analysis of the MOCCA simulations, and show some first results by investigating the present-day population of cataclysmic variables in globular clusters. Emphasis was given on their properties and the observational selection effects when observing and detecting them. In this work we analysed in this work six models, including three with Kroupa distributions of the initial binaries. We found that for models with Kroupa initial distributions, considering the standard value of the efficiency of the common envelope phase adopted in BSE, no single cataclysmic variable was formed only via binary stellar evolution, i. e., in order to form them, strong dynamical interactions have to take place. We show and explain why this is inconsistent with observational and theoretical results. Our results indicate that the population of cataclysmic var...

  3. Exploratory Spectroscopy of Magnetic Cataclysmic Variables Candidates and Other Variable Objects

    Science.gov (United States)

    Oliveira, A. S.; Rodrigues, C. V.; Cieslinski, D.; Jablonski, F. J.; Silva, K. M. G.; Almeida, L. A.; Rodríguez-Ardila, A.; Palhares, M. S.

    2017-04-01

    The increasing number of synoptic surveys made by small robotic telescopes, such as the photometric Catalina Real-Time Transient Survey (CRTS), provides a unique opportunity to discover variable sources and improves the statistical samples of such classes of objects. Our goal is the discovery of magnetic Cataclysmic Variables (mCVs). These are rare objects that probe interesting accretion scenarios controlled by the white-dwarf magnetic field. In particular, improved statistics of mCVs would help to address open questions on their formation and evolution. We performed an optical spectroscopy survey to search for signatures of magnetic accretion in 45 variable objects selected mostly from the CRTS. In this sample, we found 32 CVs, 22 being mCV candidates, 13 of which were previously unreported as such. If the proposed classifications are confirmed, it would represent an increase of 4% in the number of known polars and 12% in the number of known IPs. A fraction of our initial sample was classified as extragalactic sources or other types of variable stars by the inspection of the identification spectra. Despite the inherent complexity in identifying a source as an mCV, variability-based selection, followed by spectroscopic snapshot observations, has proved to be an efficient strategy for their discoveries, being a relatively inexpensive approach in terms of telescope time. Based on observations obtained at the Observatório do Pico dos Dias/LNA, and at the Southern Astrophysical Research (SOAR) telescope, which is a joint project of the Ministério da Ciência, Tecnologia, e Inovação (MCTI) da República Federativa do Brasil, the U.S. National Optical Astronomy Observatory (NOAO), the University of North Carolina at Chapel Hill (UNC), and Michigan State University (MSU).

  4. The Eclipsing Cataclysmic Variable Lanning 386: Dwarf Nova, SW Sextantis Star, or Both?

    OpenAIRE

    Brady, S; Thorstensen, J.R.; Koppelman, M. D.; Prieto, J. L.; Garnavich, P. M.; Hirschauer, A.; Florack, M.

    2008-01-01

    We present photometry and spectroscopy of the suspected cataclysmic variable (CV) Lanning 386. We confirm that it is a CV, and observe deep eclipses, from which we determine the orbital period Porb to be 0.1640517 +- 0.0000001 d (= 3.94 h). Photometric monitoring over two observing seasons shows a very active system with frequent outbursts of variable amplitude, up to approx. 2 mag. The spectrum in quiescence is typical of dwarf novae, but in its high state the system shows strong HeII emissi...

  5. On the origin of the peculiar cataclysmic variable AE Aquarii

    CERN Document Server

    Beskrovnaya, N G

    2014-01-01

    The nova-like variable AE Aquarii is a close binary system containing a red dwarf and a magnetized white dwarf rotating with the period of 33 seconds. A short spin period of the white dwarf is caused by an intensive mass exchange between the system components during a previous epoch. We show that a high rate of disk accretion onto the white dwarf surface resulted in temporary screening of its magnetic field and spin-up of the white dwarf to its present spin period. Transition of the white dwarf to the ejector state occurred at a final stage of the spin-up epoch after its magnetic field had emerged from the accreted plasma due to diffusion. In the frame of this scenario AE Aqr represents a missing link in the chain of Polars evolution and the white dwarf resembles a recycled pulsar.

  6. Boundary-layer temperatures in high accretion rate cataclysmic variables

    Energy Technology Data Exchange (ETDEWEB)

    Hoare, M.G.; Drew, J.E. (Oxford Univ. (UK). Dept. of Physics Oxford Univ. (UK). Dept. of Astrophysics)

    1991-04-01

    We use the Zanstra method to derive limits on boundary-layer temperatures in eclipsing dwarf novae during outburst and nova-like variables, using the observed He II {lambda}1640 and {lambda}4686 recombination lines. It is assumed that all the emission is produced in the wind rather than the accretion disc. This method constrains the boundary-layer temperatures to between 50 000 and 100 000 K depending on the degree of wind bipolarity. These estimates are lower than the T>or approx200 000 K predicted theoretically. Possible explanations include rapid rotation of the white dwarf and spreading of the boundary layer over the entire white-dwarf surface. (author).

  7. AN ONLINE CATALOG OF CATACLYSMIC VARIABLE SPECTRA FROM THE FAR-ULTRAVIOLET SPECTROSCOPIC EXPLORER

    Energy Technology Data Exchange (ETDEWEB)

    Godon, Patrick; Sion, Edward M. [Astronomy and Astrophysics, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085 (United States); Levay, Karen [Space Telescope Science Institute, Baltimore, MD 21218 (United States); Linnell, Albert P.; Szkody, Paula [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195-1580 (United States); Barrett, Paul E. [United States Naval Observatory, Washington, DC 20392 (United States); Hubeny, Ivan [Steward Observatory and Department of Astronomy and Astrophysics, University of Arizona, Tucson, AZ 85721 (United States); Blair, William P., E-mail: patrick.godon@villanova.edu, E-mail: edward.sion@villanova.edu, E-mail: klevay@stsci.edu, E-mail: linnell@astro.washington.edu, E-mail: szkody@astro.washington.edu, E-mail: barrett.paul@usno.navy.mil, E-mail: hubeny@as.arizona.edu, E-mail: wpb@pha.jhu.edu [Henry A. Rowland Department of Physics and Astronomy, The Johns Hopkins University, Baltimore, MD 21218 (United States)

    2012-12-15

    We present an online catalog containing spectra and supporting information for cataclysmic variables that have been observed with the Far-Ultraviolet Spectroscopic Explorer (FUSE). For each object in the catalog we list some of the basic system parameters such as (R.A., decl.), period, inclination, and white dwarf mass, as well as information on the available FUSE spectra: data ID, observation date and time, and exposure time. In addition, we provide parameters needed for the analysis of the FUSE spectra such as the reddening E(B - V), distance, and state (high, low, intermediate) of the system at the time it was observed. For some of these spectra we have carried out model fits to the continuum with synthetic stellar and/or disk spectra using the codes TLUSTY and SYNSPEC. We provide the parameters obtained from these model fits; this includes the white dwarf temperature, gravity, projected rotational velocity, and elemental abundances of C, Si, S, and N, together with the disk mass accretion rate, the resulting inclination, and model-derived distance (when unknown). For each object one or more figures are provided (as gif files) with line identification and model fit(s) when available. The FUSE spectra and the synthetic spectra are directly available for download as ASCII tables. References are provided for each object, as well as for the model fits. In this article we present 36 objects, and additional ones will be added to the online catalog in the future. In addition to cataclysmic variables, we also include a few related objects, such as a wind-accreting white dwarf, a pre-cataclysmic variable, and some symbiotics.

  8. On the eclipsing cataclysmic variable star HBHA 4705-03

    CERN Document Server

    Rutkowski, A; Marsh, T R; Eker, Z

    2013-01-01

    We present observations and analysis of a new eclipsing binary HBHA 4705-03. Using decomposition of the light curve into accretion disk and hot spot components, we estimated photometrically the mass ratio of the studied system to be q=0.62 +-0.07. Other fundamental parameters was found with modeling. This approach gave: white dwarf mass M_1 = (0.8 +- 0.2) M_sun, secondary mass M_2=(0.497 +- 0.05) M_sun, orbital radius a=1.418 R_sun, orbital inclination i = (81.58 +- 0.5) deg, accretion disk radius r_d/a = 0.366 +- 0.002, and accretion rate dot{M} = (2.5 +- 2) * 10^{18}[g/s], (3*10^{-8} [M_sun/yr]). Power spectrum analysis revealed ambiguous low-period Quasi Periodic Oscillations centered at the frequencies f_{1}=0.00076 Hz, f_2=0.00048 Hz and f_3=0.00036 Hz. The B-V=0.04 [mag] color corresponds to a dwarf novae during an outburst. The examined light curves suggest that HBHA 4705-03 is a nova-like variable star.

  9. On the long term evolution of white dwarfs in cataclysmic variables and their recurrence times

    Science.gov (United States)

    Sion, E. M.; Starrfield, S. G.

    1985-01-01

    The relevance of the long term quasi-static evolution of accreting white dwarfs to the outbursts of Z Andromeda-like symbiotics; the masses and accretion rates of classical nova white dwarfs; and the observed properties of white dwarfs detected optically and with IUE in low M dot cataclysmic variables is discussed. A surface luminosity versus time plot for a massive, hot white dwarf bears a remarkable similarity to the outburst behavior of the hot blue source in Z Andromeda. The long term quasi-static models of hot accreting white dwarfs provide convenient constraints on the theoretically permissible parameters to give a dynamical (nova-like) outburst of classic white dwarfs.

  10. Cataclysmic Variables From the Sloan Digital Sky Survey. VI. the Sixth Year (2005)

    Energy Technology Data Exchange (ETDEWEB)

    Szkody, Paula; /Washington U., Seattle, Astron. Dept.; Henden, Arne; /Naval Observ., Flagstaff /AAVSO, Cambridge; Mannikko, Lee; Mukadam, Anjum; /Washington U., Seattle,; Schmidt, Gary D.; /Arizona U., Astron. Dept. - Steward Observ.; Bochanski, John J.; Agueros, Marcel; Anderson, Scott F.; Silvestri, Nicole M.; /Washington U., Seattle,; Dahab, William E.; /Princeton U. Observ.; Oguri, Masamune; /Princeton U. Observ. /KIPAC, Menlo Park; Schneider, Donald P.; /Penn State U., Astron. Astrophys.; Shin,; Strauss, Michael A.; Knapp, Gillian R.; /Princeton U. Observ.; West, Andrew A.; /Washington U., Seattle, Astron. Dept.

    2007-06-15

    The 28 cataclysmic variables found in 2005 in the Sloan Digital Sky Survey are presented with their coordinates, magnitudes and spectra. Five of these systems are previously known CVs (HH Cnc, SX LMi, QZ Ser, RXJ1554.2+2721 and HS1016+3412) and the rest are new discoveries. Additional spectroscopic, photometric and/or polarimetric observations of 10 systems were carried out, resulting in estimates of the orbital periods for seven of the new binaries. The 23 new CVs include one eclipsing system, one new Polar and five systems whose spectra clearly reveal atmospheric absorption lines from the underlying white dwarf.

  11. SW Sex stars, old novae, and the evolution of cataclysmic variables

    CERN Document Server

    Schmidtobreick, Linda

    2014-01-01

    The population of cataclysmic variables with orbital periods right above the period gap are dominated by systems with extremely high mass transfer rates, the so-called SW Sextantis stars. On the other hand, some old novae in this period range which are expected to show high mass transfer rate instead show photometric and/or spectroscopic resemblance to low mass transfer systems like dwarf novae. We discuss them as candidates for so-called hibernating systems, CVs that changed their mass transfer behaviour due to a previously experienced nova outburst. This paper is designed to provide input for further research and discussion as the results as such are still very preliminary.

  12. Substellar secondaries in zero-age cataclysmic variables

    Directory of Open Access Journals (Sweden)

    M. Politano

    2004-01-01

    Full Text Available Se investiga la formaci on actual de variables catacl smicas (CVs con secundarias de enanas marrones (BD utilizando la t ecnica de s ntesis de poblaci on. En el c odigo de s ntesis de poblaci on se incorporaron resultados de los ultimos modelos detallados para las BDs. Encontramos que CVs de edad cero (ZACVs con secundarias BDs poseen per odos orbitales comprendidos en el intervalo 46 min { 2.5 horas, formando el 18% del total de la poblaci on actual de ZACVs. Por lo tanto encontramos que el 15% de la poblaci on actual de ZACVs deber a tener per odos orbitales m as cortos que el per odo orbital m nimo observado para CVs. Investigamos tambi en la dependencia de la tasa actual de formaci on de CVs con secundarias BD con el valor asumido del par ametro de e ciencia de la envolvente com un CE, asumiendo tres distribuciones de cociente de masas diferentes para binarias ZAMS. Encontramos que el proceso de la envolvente com un debe de ser extremadamente ine ciente ( CE < 0:1 como para que no se formen CVs con BD secundarias. Finalmente encontramos que las binarias progenitoras de ZACVs con secundarias BD poseen separaciones orbitales < 3AU y masas primarias entre 1 y 10 M con 75% de las masas primarias menores que 1.6 M . Es interesante se~nalar que estos intervalos en separaci on orbital y masa primaria colocan a la mayor a de estas binarias progenitoras dentro del llamado \\desierto de enanas marrones".

  13. Dwarf nova-type cataclysmic variable stars are significant radio emitters

    CERN Document Server

    Coppejans, Deanne L; Miller-Jones, James C A; Rupen, Michael P; Sivakoff, Gregory R; Knigge, Christian; Groot, Paul J; Woudt, Patrick A; Waagen, Elizabeth O; Templeton, Matthew

    2016-01-01

    We present 8--12\\,GHz radio light curves of five dwarf nova (DN) type Cataclysmic Variable stars (CVs) in outburst (RX And, U Gem and Z Cam), or superoutburst (SU UMa and YZ Cnc), increasing the number of radio-detected DN by a factor of two. The observed radio emission was variable on time-scales of minutes to days, and we argue that it is likely to be synchrotron emission. This sample shows no correlation between the radio luminosity and optical luminosity, orbital period, CV class, or outburst type; however higher-cadence observations are necessary to test this, as the measured luminosity is dependent on the timing of the observations in these variable objects. The observations show that the previously detected radio emission from SS Cyg is not unique in type, luminosity (in the plateau phase of the outburst), or variability time-scales. Our results prove that DN, as a class, are radio emitters in outburst.

  14. Spectroscopic Orbital Periods for 29 Cataclysmic Variables from the Sloan Digital Sky Survey

    CERN Document Server

    Thorstensen, John R; Peters, Christopher S; Skinner, Julie N; Southworth, John; Gaensicke, Boris T

    2015-01-01

    We report follow-up spectroscopy of 29 cataclysmic variables from the Sloan Digital Sky Survey (SDSS), 22 of which were discovered by SDSS and seven other previously known systems that were recovered in SDSS. The periods for 16 of these objects were included in the tabulation by Gaensicke et al. (2009). While most of the systems have periods less than 2 hours, only one has a period in the 80-86 minute 'spike' found by Gaensicke et al. (2009), and 11 have periods longer than 3 hours, indicating that the present sample is skewed toward longer-period, higher-luminosity objects. Seven of the objects have spectra resembling dwarf novae, but have apparently never been observed in outburst, suggesting that many cataclysmics with relatively low variability amplitude remain to be discovered. Some of the objects are notable. SDSS J07568+0858 and SDSS J08129+1911 were previously known to have deep eclipses; in addition to spectroscopy, we use archival data from the CRTTS to refine their periods. We give a parallax-based...

  15. Emission line tomography of the short period cataclysmic variables CC Scl and V2051 Oph

    CERN Document Server

    Longa-Peña, P; Marsh, T

    2014-01-01

    We present time-series spectroscopy of two short period cataclysmic variables, CC Scl and V2051 Oph, to test the efficiency of Doppler tomography-based methods in constraining orbital parameters of evolved cataclysmic variables. We find that the Ca~II triplet lines offer superior diagnostics, revealing emission components from the mass donors and sharp images of the accretion discs. Furthermore, we use Monte-Carlo methods to estimate the uncertainties from ensembles of Doppler maps. We compare our new methods against traditional radial velocity methods and show that they offer a valid route towards system parameter determination. Our analysis of CC Scl suggests a low mass ratio of $q=0.08\\pm0.03$ with a primary velocity of $K_1=37\\pm14$ km/s. This mass ratio is in between the pre- and post-period minimum status, however our $K_1$ solution favours a post-period minimum system. Our derived parameters for V2051 Oph ($q= 0.16\\pm 0.03$, $K_1=97\\pm10$ km/s) are in agreement with the eclipse solution ($q=0.19\\pm0.03...

  16. Orbital periods of cataclysmic variables identified by the SDSS. VII. Four new eclipsing systems

    CERN Document Server

    Southworth, John; Gansicke, B T; Pyrzas, S

    2009-01-01

    We present photometry of nine cataclysmic variable stars identified by the Sloan Digital Sky Survey, aimed at measuring the orbital periods of these systems. Four of these objects show deep eclipses, from which we measure their orbital periods. The light curves of three of the eclipsing systems are also analysed using the LCURVE code, and their mass ratios and orbital inclinations determined. SDSS J075059.97+141150.1 has an orbital period of 134.1564 +/- 0.0008 min, making it a useful object with which to investigate the evolutionary processes of cataclysmic variables. SDSS J092444.48+080150.9 has a period of 131.2432 +/- 0.0014 min and is probably magnetic. The white dwarf ingress and egress phases are very deep and short, and there is no clear evidence that this object has an accretion disc. SDSS J115207.00+404947.8 and SDSS J152419.33+220920.1 are nearly identical twins, with periods of 97.5 +/- 0.4 and 93.6 +/- 0.5 min and mass ratios of 0.14 +/- 0.03 and 0.17 +/- 0.03, respectively. Their eclipses have w...

  17. Evolution of accretion disc flow in cataclysmic variables. 3. Outburst properties of constant and uniform-. cap alpha. model discs

    Energy Technology Data Exchange (ETDEWEB)

    Lin, D.N.C.; Faulkner, J. (Lick Observatory, Santa Cruz, CA (USA); California Univ., Santa Cruz (USA). Board of Studies in Astronomy and Astrophysics); Papaloizou, J. (Queen Mary Coll., London (UK). Dept. of Applied Mathematics)

    1985-01-01

    The investigation of accretion disc models relevant to cataclysmic-variable systems is continued. This paper examines the stability and evolution of some simple accretion disc models in which the viscosity is prescribed by an ad hoc uniform-..cap alpha.. model. It is primarily concerned with systems in which the mass-input rate from the secondary to the disc around the primary is assumed to be constant. However, initial calculations with variable mass-input rates are also performed. The time-dependent visual magnitude light-curves are constructed for cataclysmic binaries with a range of disc size, primary mass, mass-input rate, and magnitude of viscosity.

  18. MASTER OT J190519.41+301524.4: New Eclipsing Cataclysmic Variable of VY Scl Type

    CERN Document Server

    Martinelli, F

    2016-01-01

    MASTER OT J190519.41+301524.4 was discovered as an optical transient of 15.7m by the Mobile Astronomical System of TElescope-Robots in March 2014. We report the results of photometric observations of this variable performed at Lajatico Astronomical Center in June-July 2015. The light curve is showing deep V-shaped eclipses with an amplitude of two magnitudes. The orbital period was determined to be 0.129694 d (3.113 h). Based on the archival observations and the shape of the orbital curve we suggest that MASTER OT J190519.41+301524.4 is a new cataclysmic variable of VY Scl type ("anti-nova") with an inclination angle close to 90 deg.

  19. SPECTROSCOPIC ORBITAL PERIODS FOR 29 CATACLYSMIC VARIABLES FROM THE SLOAN DIGITAL SKY SURVEY

    Energy Technology Data Exchange (ETDEWEB)

    Thorstensen, John R.; Taylor, Cynthia J.; Peters, Christopher S.; Skinner, Julie N. [Department of Physics and Astronomy 6127 Wilder Laboratory, Dartmouth College Hanover, NH 03755-3528 (United States); Southworth, John [Astrophysics Group Keele University Staffordshire ST5 5BG (United Kingdom); Gänsicke, Boris T. [Department of Physics University of Warwick Coventry CV4 7AL (United Kingdom)

    2015-04-15

    We report follow-up spectroscopy of 29 cataclysmic variables from the Sloan Digital Sky Survey (SDSS), 22 of which were discovered by SDSS and seven of which are previously known systems that were recovered in SDSS. The periods for 16 of these objects were included in the tabulation by Gänsicke et al. While most of the systems have periods less than 2 hr, only one has a period in the 80–86 minutes “spike” found by Gänsicke et al., and 11 have periods longer than 3 hr, indicating that the present sample is skewed toward longer-period, higher-luminosity objects. Seven of the objects have spectra resembling dwarf novae, but have apparently never been observed in outburst, suggesting that many cataclysmics with relatively low variability amplitude remain to be discovered. Some of the objects are notable. SDSS J07568+0858 and SDSS J08129+1911 were previously known to have deep eclipses; in addition to spectroscopy, we use archival data from the Catalina Real Time Transient Survey to refine their periods. We give a parallax-based distance of 195 (+54, −39) pc for LV Cnc (SDSS J09197+0857), which at P{sub orb} = 81 m has the shortest orbital period in our sample. SDSS J08091+3814 shows both the spectroscopic phase offset and phase-dependent absorption found in SW Sextantis stars. The average spectra of SDSS J08055+0720 and SDSS J16191+1351 show contributions from K-type secondaries, and SDSS J080440+0239 shows a contribution from an early M star. We use these to constrain the distances. SDSS J09459+2922 has characteristics typical of a magnetic system. SDSS11324+6249 may be a novalike variable, and if so, its orbital period (99 minutes) is unusually short for that subclass.

  20. Global MHD Simulations of Accretion Disks in Cataclysmic Variables (CVs): I. The Importance of Spiral Shocks

    CERN Document Server

    Ju, Wenhua; Zhu, Zhaohuan

    2016-01-01

    We present results from the first global 3D MHD simulations of accretion disks in Cataclysmic Variable (CV) systems in order to investigate the relative importance of angular momentum transport via turbulence driven by the magnetorotational instability (MRI) compared to that driven by spiral shock waves. Remarkably, we find that even with vigorous MRI turbulence, spiral shocks are an important component to the overall angular momentum budget, at least when temperatures in the disk are high (so that Mach numbers are low). In order to understand the excitation, propagation, and damping of spiral density waves in our simulations more carefully, we perform a series of 2D global hydrodynamical simulations with various equation of states and both with and without mass inflow via the Lagrangian point (L1). Compared with previous similar studies, we find the following new results. 1) Linear wave dispersion relation fits the pitch angles of spiral density waves very well. 2) We demonstrate explicitly that mass accreti...

  1. Two Rare Magnetic Cataclysmic Variables with Extreme Cyclotron Features Identified in the Sloan Digital Sky Survey

    CERN Document Server

    Szkody, P; Schmidt, G; Hall, P B; Margon, B; Miceli, A; Subba-Rao, M; Frith, W J; Harris, H; Szkody, Paula; Anderson, Scott F.; Schmidt, Gary; Hall, Patrick B.; Margon, Bruce; Miceli, Antonino; Rao, Mark Subba; Frith, James; Harris, Hugh

    2003-01-01

    Two newly identified magnetic cataclysmic variables discovered in the Sloan Digital Sky Survey (SDSS), SDSSJ155331.12+551614.5 and SDSSJ132411.57+032050.5, have spectra showing highly prominent, narrow, strongly polarized cyclotron humps with amplitudes that vary on orbital periods of 4.39 and 2.6 hrs, respectively. In the former, the spacing of the humps indicates the 3rd and 4th harmonics in a magnetic field of ~60 MG. The narrowness of the cyclotron features and the lack of strong emission lines imply very low temperature plasmas and very low accretion rates, so that the accreting area is heated by particle collisions rather than accretion shocks. The detection of rare systems like these exemplifies the ability of the SDSS to find the lowest accretion rate close binaries.

  2. A 6.3-h superhump in the cataclysmic variable TV Columbae the longest yet seen

    CERN Document Server

    Retter, A; Augusteijn, T; Naylor, T; Bedding, T R; Bembrick, C; McCormick, J; Velthuis, F

    2002-01-01

    We present results from a two week multi-longitude photometric campaign on TV Col held in 2001 January. The data confirm the presence of a permanent positive superhump found in re-examination of extensive archive photometric data of TV Col. The 6.3-h period is 15 per cent longer than the orbital period and obeys the well known relation between superhump period excess and binary period. At 5.5-h, TV Col has an orbital period longer than any known superhumping cataclysmic variable and, therefore, a mass ratio which might be outside the range at which superhumps can occur according to the current theory. We suggest several solutions for this problem.

  3. XMM-Newton and Optical Observations of Cataclysmic Variables from the Sloan Digital Sky Survey

    Science.gov (United States)

    Hilton, Eric J.; Szkody, Paula; Mukadam, Anjum; Henden, Arne; Dillon, William; Schmidt, Gary D.

    2009-03-01

    We report on XMM-Newton and optical results for six cataclysmic variables that were selected from Sloan Digital Sky Survey (SDSS) spectra because they showed strong He II emission lines, indicative of being candidates for containing white dwarfs with strong magnetic fields. While high X-ray background rates prevented optimum results, we are able to confirm SDSS J233325.92+152222.1 as an intermediate polar from its strong pulse signature at 21 minutes and its obscured hard X-ray spectrum. Ground-based circular polarization and photometric observations were also able to confirm SDSS J142256.31 - 022108.1 as a polar with a period near 4 hr. Photometry of SDSS J083751.00+383012.5 and SDSS J093214.82+495054.7 solidifies the orbital period of the former as 3.18 hr and confirms the latter as a high-inclination system with deep eclipses.

  4. Rapid Oscillations in Cataclysmic Variables. XV. HT Camelopardalis (= RX J0757.0+6306)

    CERN Document Server

    Kemp, J; Thorstensen, J R; Fried, R E; Skillman, D R; Billings, G W; Kemp, Jonathan; Patterson, Joseph; Thorstensen, John; Fried, Robert; Skillman, David; Billings, Gary

    2002-01-01

    We present photometry and spectroscopy of HT Camelopardalis, a recently discovered X-ray-bright cataclysmic variable. The spectrum shows bright lines of H, He I, and He II, all moving with a period of 0.059712(1) d, which we interpret as the orbital period. The star's brightness varies with a strict period of 515.0592(2) s, and a mean full amplitude of 0.11 mag. These properties qualify it as a /bona fide/ DQ Herculis star (intermediate polar) -- in which the magnetism of the rapidly rotating white dwarf channels accretion flow to the surface. Normally at V=17.8, the star shows rare and very brief outbursts to V=12-13. We observed one in December 2001, and found that the 515 s pulse amplitude had increased by a factor of ~100 (in flux units). A transient orbital signal may also have appeared.

  5. Investigations of a new eclipsing cataclysmic variable HBHA 4705-03

    CERN Document Server

    Yakin, D G; Shimansky, V V; Vlasyuk, V V; Spiridonova, O I

    2012-01-01

    Results of photometric and spectroscopic investigations of the recently discovered eclipsing cataclysmic variable star HBHA 4705-03 are presented. The emission spectra of the system show broad hydrogen and helium emission lines. The bright spots with an approximately zero velocity components are found in the Doppler maps for the hydrogen and ionized helium lines. The disc structure is more prominent in the maps for the neutral helium lines. The masses of the components (M_WD = 0.54 \\pm 0.10 M_sun and M_RD = 0.45 \\pm 0.05 M_sun), and the orbit inclination (i = 71.8 \\pm 0.^7 deg) were estimated using the radial velocity light curve and the eclipse width. The modeling of the light curve allows us to evaluate the bright spot parameters and the mass accretion rate (\\dot M \\approx 2 10^{17} g s^{-1}).

  6. Statistical properties of dwarf novae-type cataclysmic variables: The Outburst Catalogue

    CERN Document Server

    Coppejans, Deanne L; Knigge, Christian; Pretorius, Margaretha L; Woudt, Patrick A; Groot, Paul J; Van Eck, Cameron L; Drake, Andrew J

    2015-01-01

    The Outburst Catalogue contains a wide variety of observational properties for 722 dwarf nova-type (DN) cataclysmic variables (CVs) and 309 CVs of other types from the Catalina Real-time Transient Survey. In particular, it includes the apparent outburst and quiescent V-band magnitudes, duty cycles, limits on the recurrence time, upper- and lower-limits on the distance and absolute quiescent magnitudes, colour information, orbital parameters, and X-ray counterparts. These properties were determined by means of a classification script presented in this paper. The DN in the catalogue show a correlation between the outburst duty cycle and the orbital period (and outburst recurrence time), as well as between the quiescent absolute magnitude and the orbital period (and duty cycle). This is the largest sample of dwarf nova properties collected to date. Besides serving as a useful reference for individual systems and a means of selecting objects for targeted studies, it will prove valuable for statistical studies tha...

  7. On the diversity and similarity of outbursts of symbiotic binaries and cataclysmic variables

    CERN Document Server

    Skopal, Augustin

    2015-01-01

    Outbursts in two classes of interacting binary systems, the symbiotic stars (SSs) and the cataclysmic variables (CVs), show a number of similarities in spite of very different orbital periods. Typical values for SSs are in the order of years, whereas for CVs they are of a few hours. Both systems undergo unpredictable outbursts, characterized by a brightening in the optical by 1 - 3 and 7 - 15 mag for SSs and CVs, respectively. By modelling the multiwavelength SED of selected examples from both groups of these interacting binaries, I determine their basic physical parameters at a given time of the outburst evolution. In this way I show that the principal difference between outbursts of these objects is their violence, whereas the ionization structure of their ejecta is basically very similar. This suggests that the mechanism of the mass ejection by the white dwarfs in these systems is also similar.

  8. Short-period cataclysmic variables at Observatorio Astronomico Nacional IA UNAM.

    Science.gov (United States)

    Zharikov, S.

    2014-03-01

    We present results of time-resolved spectroscopy and photometry of faint (∼17-19 mag) Cataclysmic Variable stars with periods around the minimum orbital period (∼80 min). In this work we concentrated to our results of study of CVs systems which have evolved beyond the period minimum (so-called bounce-back systems). Using various instruments attached to 2.1m, 1.5m and 0.84m telescopes of OAN SPM of IA UNAM we explored conditions and structure of accretion disks in those short-period Cataclysmic Variables. We showed that the accretion disk in a system with an extremely low mass ratio (≤0.05) grows in the size reaching 2:1 resonance radius and is relatively cool. The disk in such systems also becomes largely optically thin in the continuum, contributing to the total flux less than the stellar components of the system. In contrast, the viscosity and the temperature in spiral arms formed at the outer edge of the disk are higher and their contribution in continuum plays an increasingly important role. We model such disks and generate light curves which successfully simulate the observed double-humped light curves in the quiescence. Thanks to support of our programs by the Time Allocation Commission of OAN SPM, the perfect astroclimate in the observatory, and the phase-locked method of spectroscopic observations, the significant progress in the study of bounce-back systems using a small size telescope was reached.

  9. XMM-Newton observations of the low-luminosity cataclysmic variable V405 Pegasi

    CERN Document Server

    Schwope, A D; Traulsen, I; Schwarz, R; Granzer, T; Pires, A M; Thorstensen, J R

    2013-01-01

    V405 Peg is a low-luminosity cataclysmic variable (CV) that was identified as the optical counterpart of the bright, high-latitude ROSAT all-sky survey source RBS1955. The system was suspected to belong to a largely undiscovered population of hibernating CVs. Despite intensive optical follow-up its subclass however remained undetermined. We want to further classify V405 Peg and understand its role in the CV zoo via its long-term behaviour, spectral properties, energy distribution and accretion luminosity. We perform a spectral and timing analysis of \\textit{XMM-Newton} X-ray and ultra-violet data. Archival WISE, HST, and Swift observations are used to determine the spectral energy distribution and characterize the long-term variability. The X-ray spectrum is characterized by emission from a multi-temperature plasma. No evidence for a luminous soft X-ray component was found. Orbital phase-dependent X-ray photometric variability by $\\sim50\\%$ occurred without significant spectral changes. No further periodicity...

  10. Disk Structure of Cataclysmic Variables in the light of Broadband Noise Characteristics

    Science.gov (United States)

    Balman, Solen

    2016-07-01

    Flicker noise and its variations in accreting systems have been a diagnostic tool in understanding the structure in accretion disks. I study the nature of time variability of brightness of non-magnetic cataclysmic variables. Dwarf novae demonstrate band limited noise in the UV and X-ray energy bands, which can be adequately explained in the framework of the model of propagating fluctuations. The detected frequency breaks in the range (1-6) mHz indicates an optically thick disk truncation in the inner disk of some dwarf novae systems. Analysis of other available data (SS Cyg, SU UMa, WZ Sge, Z Cha) indicate that during the outburst the inner disk radius moves towards the white dwarf and receeds as the outburst declines while changes in the X-ray energy spectrum is also observed. Cross-correlations between the simultaneous Optical, UV and X-ray light curves show time lags in the X-rays consistent with truncated inner optically thick disk. I compare magnetic and nonmagnetic CVs in terms of their broadband noise characteristics and summarize findings regarding broadband noise structure and time lags in other types of nonmagnetic CVs which in general show compliance with the model of propagating fluctuations. In addition, I discuss comparisons with X-ray binaries.

  11. Observations of GAIA-identified Cataclysmic Variables Using the TUBITAK National Observatory

    Science.gov (United States)

    Esenoglu, Hasan H.; Kirbiyik, Halil; Kaynar, Suleyman; Okuyan, Oguzhan; Hamitoglu, Irek; Galeev, Almaz; Uluc, Kadir; Kocak, Murat; Kilic, Sila E.; Parmaksizoglu, Murat; Erece, Orhan; Ozisik, Tuncay; Gulsecen, Hulusi

    2016-07-01

    TUBITAK National Observatory supports the GAIA alerts with observations using three telescopes (RTT150, T100, T60) at the site with a limited time quota. We have observed 10 variable stars among GAIA sources discovered in the years 2014-2016 that may be candidate Cataclysmic Variables (CVs). Our TUG observations at this stage involve photometry and spectroscopy to aid the identification of these sources. The first preliminary result of our observations of Gaia14aat among them showed a dwarf nova outburst with an amplitude of 2.69 mag. We aim to construct a GAIA astrophysics group to study CVs along with supported studies using the SRG (Spectrum Roentgen Gamma astrophysical observatory) after the year of 2016. These observations will basically involve spectroscopy, narrow-band CCD imaging and photometry using several filters to aid the identification of these sources. RTT150 observations with very narrow filters (like H-alpha, SII, OIII with band width of range of 2 to 5 nm) will reveal whether shell around the SRG sources to aid identification novae among them.

  12. Reversibility of time series: revealing the hidden messages in X-ray binaries and cataclysmic variables

    CERN Document Server

    Scaringi, S; Middleton, M

    2014-01-01

    We explore the non-linear, high-frequency, aperiodic variability properties in the three cataclysmic variables MV Lyr, KIC 8751494 and V1504 Cyg observed with Kepler, as well as the X-ray binary Cyg X-1 observed with RXTE. This is done through the use of a high-order Fourier statistic called the bispectrum and its related biphase and bicoherence, as well as the time-skewness statistic. We show how all objects display qualitatively similar biphase trends. In particular all biphase amplitudes are found to be smaller than $\\pi/2$, suggesting that the flux distributions for all sources are positively skewed on all observed timescales, consistent with the log-normal distributions expected from the fluctuating accretion disk model. We also find that for all objects the biphases are positive at frequencies where the corresponding power spectral densities display their high frequency break. This suggests that the noise-like flaring observed is rising more slowly than it is falling, and thus not time-reversible. This ...

  13. KIC 9406652: An Unusual Cataclysmic Variable in the Kepler Field of View

    CERN Document Server

    Gies, Douglas R; Howell, Steve B; Still, Martin D; Boyajian, Tabetha S; Hoekstra, Abe J; Jek, Kian J; LaCourse, Daryll; Winarski, Troy

    2013-01-01

    KIC 9406652 is a remarkable variable star in the Kepler field of view that shows both very rapid oscillations and long term outbursts in its light curve. We present an analysis of the light curve over quarters 1 to 15 and new spectroscopy that indicates that the object is a cataclysmic variable with an orbital period of 6.108 hours. However, an even stronger signal appears in the light curve periodogram for a shorter period of 5.753 hours, and we argue that this corresponds to the modulation of flux from the hot spot region in a tilted, precessing disk surrounding the white dwarf star. We present a preliminary orbital solution from radial velocity measurements of features from the accretion disk and the photosphere of the companion. We use a Doppler tomography algorithm to reconstruct the disk and companion spectra, and we also consider how these components contribute to the object's spectral energy distribution from ultraviolet to infrared wavelengths. This target offers us a remarkable opportunity to invest...

  14. Photometric study of selected cataclysmic variables II. Time-series photometry of nine systems

    CERN Document Server

    Papadaki, C; Stanishev, V; Boumis, P; Akras, S; Sterken, C

    2008-01-01

    We present time-series photometry of nine cataclysmic variables: EI UMa, V844Her, V751 Cyg, V516 Cyg, GZ Cnc, TY Psc, V1315 Aql, ASAS J002511+1217.12, V1315 Aql and LN UMa. The observations were conducted at various observatories, covering 170 hours and comprising 7,850 data points in total. For the majority of targets we confirm previously reported periodicities and for some of them we give, for the first time, their spectroscopic orbital periods. For those dwarf-nova systems which we observed during both quiescence and outburst, the increase in brightness was followed by a decrease in the amount of flickering. Quasi-periodic oscillations have either been discovered, or were confirmed. For the eclipsing system V1315 Aql we have covered 9 eclipses, and obtained a refined orbital ephemeris. We find that, during its long baseline of observations, no change in the orbital period of this system has occurred. V1315 Aql also shows eclipses of variable depth.

  15. BK Lyncis: The Oldest Old Nova?... And a Bellwether for Cataclysmic-Variable Evolution

    CERN Document Server

    Patterson, Joseph; Kemp, Jonathan; de Miguel, Enrique; Krajci, Thomas; Foote, Jerry; Hambsch, Franz-Josef; Campbell, Tut; Roberts, George; Cejudo, David; Dvorak, Shawn; Vanmunster, Tonny; Koff, Robert; Skillman, David; Harvey, David; Martin, Brian; Rock, John; Boyd, David; Oksanen, Arto; Morelle, Etienne; Ulowetz, Joseph; Kroes, Anthony; Sabo, Richard; Jensen, Lasse

    2012-01-01

    We summarize the results of a 20-year campaign to study the light curves of BK Lyncis, a nova-like star strangely located below the 2-3 hour orbital period gap in the family of cataclysmic variables. Two apparent "superhumps" dominate the nightly light curves - with periods 4.6% longer, and 3.0% shorter, than P_orb. The first appears to be associated with the star's brighter states (V~14), while the second appears to be present throughout and becomes very dominant in the low state (V~15.7). Starting in the year 2005, the star's light curve became indistinguishable from that of a dwarf nova - in particular, that of the ER UMa subclass. Reviewing all the star's oddities, we speculate: (a) BK Lyn is the remnant of the probable nova on 30 December 101, and (b) it has been fading ever since, but has taken ~2000 years for the accretion rate to drop sufficiently to permit dwarf-nova eruptions. If such behavior is common, it can explain other puzzles of CV evolution. One: why the ER UMa class even exists (because all...

  16. The Emergence of Negative Superhumps in Cataclysmic Variables: Smoothed Particle Hydrodynamics Simulations

    CERN Document Server

    Thomas, David M

    2016-01-01

    Negative superhumps are believed to arise in cataclysmic variable systems when the accretion disk is tilted with respect to the orbital plane. Slow retrograde precession of the line-of-nodes results in a signal---the negative superhump---with a period slightly less than the orbital period. Previous studies have shown that tilted disks exhibit negative superhumps, but a consensus on how a disk initially tilts has not been reached. Analytical work by Lai suggests that a magnetic field on the primary can lead to a tilt instability in a disk when the dipole moment is offset in angle from the spin axis of the primary and when the primary's spin axis is, itself, not aligned with the angular momentum axis of the binary orbit. However, Lai did not apply his work to the formation of negative superhumps. In this paper, we add Lai's model to an existing smoothed particle hydrodynamics code. Using this code, we demonstrate the emergence of negative superhumps in the "light curve" for a range of magnetic dipole moments. W...

  17. Radial velocity studies of HeII and Hβ emission from cataclysmic variables

    Science.gov (United States)

    Schwarz, C.; Montgomery, M. M.

    2014-02-01

    Radial velocity (RV) plots of HeII and Hβ emission lines from non-magnetic Cataclysmic Variable (CV) systems are frequently fit with a sin curve but sometimes contain outlying data points around phase ϕ∼1.0. A lack of consensus exists on the origin of these outlying points. In this work, we develop an analytical model that is based upon our 3D Smoothed Particle Hydrodynamic (SPH) numerical model to simulate these RV curves. Our chosen targets are CV SW Sextanis-like systems UX Uma and RW Tri as well as SU UMa dwarf novae systems Hα0242-28 and 1RXSJ1808+10, which have secondary-to-primary mass ratios of q = (0.43, 0.86, 0.27, 0.18), respectively. In our model, we include disk eccentricity, inclination angle, degree of disk-tilt, bright spot (s), and/or gas stream overflow. Our model provides good non-sinusoidal fits to the observed RV data, including outlying data points near ϕ∼1.0, suggesting these excess points may be caused by gas-stream overflow.

  18. Doppler Tomography and Photometry of the Cataclysmic Variable 1RXS J064434.5+334451

    CERN Document Server

    Santisteban, J V Hernández; Michel, R; Costero, R

    2016-01-01

    We have obtained simultaneous photometric and spectroscopic observations of the cataclysmic variable 1RXS J064434.5+334451. We have calibrated the spectra for slit losses using the simultaneous photometry allowing to construct reliable Doppler images from H$\\alpha$ and HeII 4686 emission lines. We have improved the ephemeris of the object based on new photometric eclipse timings, obtaining $HJD = 2453403.759533 + 0.26937446E$. Some eclipses present a clear internal structure which we attribute to a central HeII emission region surrounding the white dwarf, a finding supported by the Doppler tomography. This indicates that the system has a large inclination angle $i=78 \\pm 2^{\\circ}$. We have also analysed the radial velocity curve from the emission lines to measure its semi--amplitude, $K_1$, from H$\\alpha$ and HeII 4686 and derive the masses of the components: $M_1=0.82\\pm0.06$ M$_{\\odot}$, $M_2=0.78\\pm0.04$ M$_{\\odot}$ and their separation $a=2.01\\pm0.06$ $R_{\\odot}$. The Doppler tomography and other observe...

  19. ULTRACAM photometry of the eclipsing cataclysmic variables XZ Eri and DV UMa

    CERN Document Server

    Feline, W J; Marsh, T R; Brinkworth, C S

    2004-01-01

    We present high-speed, three-colour photometry of the faint eclipsing cataclysmic variables XZ Eri and DV UMa. We determine the system parameters through two techniques: first, timings of the eclipse contact phases of the white dwarf and bright-spot using the derivative of the light curve; and secondly, a parameterized model of the eclipse fitted to the observed light curve by chi-squared minimisation. For both objects, we prefer the latter method, as it is less affected by photon noise and rapid flickering. For XZ Eri we obtain a mass ratio q = 0.1098 +/- 0.0017 and an orbital inclination i = 80.16 +/- 0.09 degrees. For DV UMa we derive figures of q = 0.1506 +/- 0.0009 and i = 84.24 +/- 0.07 degrees. The secondary star in XZ Eri has a very low mass Mr/Msun = 0.0842 +/- 0.0024, placing it close to the upper limit on the mass of a brown dwarf.

  20. ULTRACAM photometry of the eclipsing cataclysmic variables GY Cnc, IR Com and HT Cas

    CERN Document Server

    Feline, W J; Marsh, T R; Watson, C A; Littlefair, S P

    2005-01-01

    We present high-speed, three-colour photometry of the eclipsing cataclysmic variables GY Cnc, IR Com and HT Cas. We find that the sharp eclipses in GY Cnc and IR Com are due to eclipses of the white dwarf. There is some evidence for a bright spot on the edge of the accretion disc in GY Cnc, but not in IR Com. Eclipse mapping of HT Cas is presented which shows changes in the structure of the quiescent accretion disc. Observations in 2002 show the accretion disc to be invisible except for the presence of a bright spot at the disc edge. 2003 observations, however, clearly show a bright inner disc and the bright spot to be much fainter than in 2002. Although no outburst was associated with either set of quiescent observations, the system was ~0.6 mJy brighter in 2003, mainly due to the enhanced emission from the inner disc. We propose that these changes are due to variations in the mass transfer rate from the secondary star and through the disc. The disc colours indicate that it is optically thin in both its inne...

  1. THE ROLE OF WHITE DWARFS IN CATACLYSMIC VARIABLE SPIN-DOWN

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, O.; Drake, J. J.; Kashyap, V. L. [Harvard-Smithsonian Center for Astrophysics, 60 Garden St. Cambridge, MA 02138 (United States)

    2012-02-10

    We study the effect of a white dwarf on the spin-down of a cataclysmic variable (CV) system using a three-dimensional magnetohydrodynamic numerical model. The model includes the stellar corona, the stellar wind, and the WD mass and magnetic field. The existence of the WD modifies the system spin-down by physically blocking the stellar wind, restructuring the wind, channeling the wind toward the WD surface, and modifying the shape and size of the Alfven surface. The combination of these processes differs among a set of simple test cases, and the resulting angular momentum loss rates vary by factors of 2-3, and by factors of 2 relative to a test model with a single M dwarf. While the model employs some simplifications, the results suggest that angular momentum loss schemes currently employed in CV studies do not require drastic revision. Insights are also gained on wind accretion. We find that efficient accretion switches on quite rapidly with decreasing orbital separation. Accretion rates depend on magnetic field alignment and should be modulated by magnetic cycles on the M dwarf. For particular values of white dwarf magnetic field strength, an efficient syphoning of coronal plasma from the inward facing M dwarf hemisphere occurs. Wind accretion rates are expected to vary by factors of 10 or more between fairly similar close binaries, depending on magnetic field strengths and orbital separation.

  2. Roche tomography of cataclysmic variables - VI. Differential rotation of AE Aqr - Not tidally locked!

    CERN Document Server

    Hill, Colin; Shahbaz, Tariq; Steeghs, Danny; Dhillon, Vik

    2014-01-01

    We present Roche tomograms of the K4V secondary star in the cataclysmic variable AE Aqr, reconstructed from two datasets taken 9 days apart, and measure the differential rotation of the stellar surface. The tomograms show many large, cool starspots, including a large high-latitude spot and a prominent appendage down the trailing hemisphere. We find two distinct bands of spots around 22$^{\\circ}$ and 43$^{\\circ}$ latitude, and estimate a spot coverage of 15.4-17% on the northern hemisphere. Assuming a solar-like differential rotation law, the differential rotation of AE Aqr was measured using two different techniques. The first method yields an equator-pole lap time of 269 d and the second yields a lap time of 262 d. This shows the star is not fully tidally locked, as was previously assumed for CVs, but has a co-rotation latitude of $\\sim 40^{\\circ}$. We discuss the implications that these observations have on stellar dynamo theory, as well as the impact that spot traversal across the first Lagrangian point ma...

  3. Cataclysmic Variables and a Candidate Helium White Dwarf in the Globular Cluster NGC 6397

    CERN Document Server

    Edmonds, P D; Cool, A M; Cohn, H N; Lugger, P M; Bailyn, C D; Edmonds, Peter D.; Grindlay, Jonathan E.; Cool, Adrienne M.; Cohn, Haldan N.; Lugger, Phyllis N.; Bailyn, Charles D.

    1999-01-01

    We have used HST/FOS to study faint UV stars in the core of the nearby globular cluster NGC 6397. We confirm the presence of a 4th cataclysmic variable (CV) in NGC 6397 (CV 4), and we use the photometry of Cool et al. (1998) to present evidence that CVs 1--4 all have faint disks and probably low accretion rates. By combining these results with new UV spectra of CV 1 and the published spectra of Grindlay et al. (1995) we present new evidence that CVs 1--3 may be DQ Her systems, and we show that CV 4 may either be a dwarf nova or another magnetic system. Another possibility is that the CVs could be old novae in hibernation between nova eruptions. We also present the first spectrum of a member of a new class of UV bright stars in NGC 6397. These faint, hot stars do not vary, unlike the CVs, and are thus denoted as ``non-flickerers'' (NFs). Like the CVs, their spatial concentration is strongly concentrated toward the cluster center. Using stellar atmosphere models we have determined log g = 6.25, and T_eff = 17,5...

  4. Mass transfer in cataclysmic variables - Clues from the dwarf nova period distribution

    Science.gov (United States)

    Shafter, A. W.; Wheeler, J. C.; Cannizzo, J. K.

    1986-01-01

    Evidence is presented in support of the hypothesis that the mean mass-transfer rate at a given orbital period is not continuous across the 2-3 hr gap in the orbital period distribution for cataclysmic variables. It is pointed out that although dwarf novae comprise nearly half (48 percent) of all disk systems with orbital periods less than 10 hr, only three systems out of the 22 with periods between 3 and 4 hr appear to be dwarf novae. The overall orbital period distribution for dwarf novae in conjunction with the predictions from current theories of dwarf nova eruptions are used to argue that mass-transfer rates must be generally higher for systems with orbital periods greater than 3 hr relative to systems with periods less than 2 hr. It is further argued that the mean mass-transfer rate at a given orbital period cannot increase more steeply than P exp 1.7 unless the white dwarf mass is positively correlated with orbital period.

  5. Roche tomography of cataclysmic variables - VII. The long-term magnetic activity of AE Aqr

    CERN Document Server

    Hill, C A; Steeghs, D; Dhillon, V S; Shahbaz, T

    2016-01-01

    We present a long-term study of the secondary star in the cataclysmic variable AE~Aqr, using Roche tomography to indirectly image starspots on the stellar surface spanning 8~years of observations. The 7 maps show an abundance of spot features at both high and low latitudes. We find that all maps have at least one large high-latitude spot region, and we discuss its complex evolution between maps, as well as its compatibility with current dynamo theories. Furthermore, we see the apparent growth in fractional spot coverage, $f_{\\mathrm{s}}$, around $45^{\\circ}$~latitude over the duration of observations, with a persistently high $f_{\\mathrm{s}}$ near latitudes of $20^{\\circ}$. These bands of spots may form as part of a magnetic activity cycle, with magnetic flux tubes emerging at different latitudes, similar to the `butterfly' diagram for the Sun. We discuss the nature of flux tube emergence in close binaries, as well as the activity of AE~Aqr in the context of other stars.

  6. An Online Catalog of Cataclysmic Variable Spectra from the Far Ultraviolet Spectroscopic Explorer

    CERN Document Server

    Godon, P; Levay, K; Linnell, A P; Szkody, P; Barrett, P E; Hubeny, I; Blair, W P

    2012-01-01

    We present an online catalog containing spectra and supporting information for cataclysmic variables that have been observed with the Far Ultraviolet Spectroscopic Explorer (FUSE). For each object in the catalog we list some of the basic system parameters such as (RA,Dec), period, inclination, white dwarf mass, as well as information on the available FUSE spectra: data ID, observation date and time, and exposure time. In addition, we provide parameters needed for the analysis of the FUSE spectra such as the reddening E(B-V), distance, and state (high, low, intermediate) of the system at the time it was observed. For some of these spectra we have carried out model fits to the continuum with synthetic stellar and/or disk spectra using the codes TLUSTY and SYNSPEC. We provide the parameters obtained from these model fits; this includes the white dwarf temperature, gravity, projected rotational velocity and elemental abundances of C, Si, S and N, together with the disk mass accretion rate, the resulting inclinati...

  7. Population Synthesis of Cataclysmic Variables: I. Inclusion of Detailed Nuclear Evolution

    CERN Document Server

    Goliasch, J

    2016-01-01

    We have carried out an extensive population synthesis study of the ensemble properties of the present-day population of cataclysmic variables (PDCVs) that takes into account the nuclear evolution of high-mass donors close to the bifurcation and dynamical instability limits. Assuming the interrupted magnetic braking paradigm, we confirm many of the general features associated with the observed CV population and find enormous diversity in their secular properties. We predict that nearly half of the non-magnetic CVs with Porb > 6 hours are at least mildly evolved (i.e., greater than one-half of their MS turn-off age). Some of these systems contribute to the observed population of PDCVs in the period gap. We also see an enhancement by up to a factor of two in the probability of detecting CVs at the `minimum period'. This spike is quite narrow (approximately 5 minutes) and is attenuated because of the spectrum of WD masses and partly by the evolution of the donors. Our syntheses imply that there should be a very r...

  8. Infrared Spectroscopic Observations of the Secondary Stars of Short Period Sub-Gap Cataclysmic Variables

    CERN Document Server

    Hamilton, Ryan T; Tappert, Claus; Howell, Steve B

    2010-01-01

    We present K-band spectroscopy of short period, "sub-gap" cataclysmic variable (CV) systems obtained using ISAAC on the VLT. We show the infrared spectra (IR) for nine systems below the 2-3 hour period gap: V2051 Oph, V436 Cen, EX Hya, VW Hyi, Z Cha, WX Hyi, V893 Sco, RZ Leo, and TY PsA. We are able to clearly detect the secondary star in all but WX Hyi, V893 Sco, and TY PsA. We present the first direct detection of the secondary stars of V2051 Oph, V436 Cen, and determine new spectral classifications for EX Hya, VW Hyi, Z Cha, and RZ Leo. We find that the CO band strengths of all but Z Cha appear normal for their spectral types, in contrast to their longer period cousins above the period gap. This brings the total number of CVs and pre-CVs with moderate resolution (R >~ 1500) IR spectroscopy to sixty-one systems: nineteen pre-CVs, thirty-one non-magnetic systems, and eleven magnetic or partially magnetic systems. We discuss the trends seen in the IR abundance patterns thus far, and highlight a potential link...

  9. Cataclysmic Variables from SDSS. VIII. The Final Year (2007-2008)

    CERN Document Server

    Szkody, Paula; Brooks, Keira; Gaensicke, Boris T; Kronberg, Martin; Riecken, Thomas; Ross, Nicholas P; Schmidt, Gary D; Schneider, Donald P; Agueros, Marcel A; Gomez-Moran, Ada N; Knapp, Gillian R; Schreiber, Matthias R; Schwope, Axel D

    2011-01-01

    This paper completes the series of cataclysmic variables (CVs) identified from the Sloan Digital Sky Survey I/II. The coordinates, magnitudes and spectra of 33 CVs are presented. Among the 33 are eight systems known previous to SDSS (CT Ser, DO Leo, HK Leo, IR Com, V849 Her, V405 Peg, PG1230+226 and HS0943+1404), as well as nine objects recently found through various photometric surveys. Among the systems identified since the SDSS are two polar candidates, two intermediate polar candidates and one candidate for containing a pulsating white dwarf. Our followup data have confirmed a polar candidate from Paper VII and determined tentative periods for three of the newly identified CVs. A complete summary table of the 285 CVs with spectra from SDSS I/II is presented as well as a link to an online table of all known CVs from both photometry and spectroscopy that will continue to be updated as future data appear.

  10. CATACLYSMIC VARIABLES FROM THE SLOAN DIGITAL SKY SURVEY. VIII. THE FINAL YEAR (2007-2008)

    Energy Technology Data Exchange (ETDEWEB)

    Szkody, Paula; Anderson, Scott F.; Brooks, Keira; Kronberg, Martin; Riecken, Thomas [Department of Astronomy, University of Washington, Seattle, WA 98195 (United States); Gaensicke, Boris T. [Department of Physics, University of Warwick, Coventry CV4 7AL (United Kingdom); Ross, Nicholas P. [Lawrence Berkeley National Lab, Berkeley, CA 92420 (United States); Schmidt, Gary D. [The University of Arizona, Steward Observatory, Tucson, AZ 85721 (United States); Schneider, Donald P. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Agueeros, Marcel A. [Department of Astronomy, Columbia University, New York, NY 10027 (United States); Gomez-Moran, Ada N.; Schwope, Axel D. [Leibniz-Institut fuer Astrophysik Potsdam (AIP), 14482 Potsdam (Germany); Knapp, Gillian R. [Princeton University Observatory, Princeton, NJ 08544 (United States); Schreiber, Matthias R., E-mail: szkody@astro.washington.edu [Departamento de Fisica y Astronomia, Universidad de Valparaiso (Chile)

    2011-12-15

    This paper completes the series of cataclysmic variables (CVs) identified from the Sloan Digital Sky Survey (SDSS) I/II. The coordinates, magnitudes, and spectra of 33 CVs are presented. Among the 33 are eight systems known prior to SDSS (CT Ser, DO Leo, HK Leo, IR Com, V849 Her, V405 Peg, PG1230+226, and HS0943+1404), as well as nine objects recently found through various photometric surveys. Among the systems identified since the SDSS are two polar candidates, two intermediate polar candidates, and one candidate for containing a pulsating white dwarf. Our follow-up data have confirmed a polar candidate from Paper VII and determined tentative periods for three of the newly identified CVs. A complete summary table of the 285 CVs with spectra from SDSS I/II is presented as well as a link to an online table of all known CVs from both photometry and spectroscopy that will continue to be updated as future data appear.

  11. Abundance Derivations for the Secondary Stars in Cataclysmic Variables from Near-Infrared Spectroscopy

    CERN Document Server

    Harrison, Thomas E

    2016-01-01

    We derive metallicities for 41 cataclysmic variables (CVs) from near-infrared spectroscopy. We use synthetic spectra that cover the 0.8 $\\mu$m $\\leq \\lambda \\leq$ 2.5 $\\mu$m bandpass to ascertain the value of [Fe/H] for CVs with K-type donors, while also deriving abundances for other elements. Using calibrations for determining [Fe/H] from the $K$-band spectra of M-dwarfs, we derive more precise values for T$_{\\rm eff}$ for the secondaries in the shortest period CVs, and examine whether they have carbon deficits. In general, the donor stars in CVs have sub-solar metallicities. We confirm carbon deficits for a large number of systems. CVs with orbital periods $>$ 5 hr are most likely to have unusual abundances. We identify four CVs with CO emission. We use phase-resolved spectra to ascertain the mass and radius of the donor in U Gem. The secondary star in U Gem appears to have a lower {\\it apparent} gravity than a main sequence star of its spectral type. Applying this result to other CVs, we find that the late...

  12. Photometry of the eclipsing cataclysmic variable SDSS J152419.33+220920.0

    CERN Document Server

    Michel, R; Hernandez-Santisteban, J V

    2013-01-01

    Aims. We present new photometry of the faint and poorly studied cataclysmic variable SDSS J152419.33+220920.0, analyze its light curve and provide an accurate ephemeris for this system. Methods. Time-resolved CCD differential photometry was carried out using the 1.5m and 0.84m telescopes at the Observatorio Astronomico Nacional at San Pedro Martir. Results. From time-resolved photometry of the system obtained during six nights (covering more than twenty primary eclipse cycles in more than three years), we show that this binary presents a strong primary and a weak secondary modulation. Our light curve analysis shows that only two fundamental frequencies are present, corresponding to the orbital period and a modulation with twice this frequency. We determine the accurate ephemeris of the system to be HJD(eclipse)= 2454967.6750(1) + 0.06531866661(1) E. A double-hump orbital period modulation, a standing feature in several bounce-back systems at quiescence, is present at several epochs. However, we found no other...

  13. HST/FOS Eclipse Observations of the Nova-like Cataclysmic Variable UX Ursae Majoris

    CERN Document Server

    Knigge, C; Wade, R A; Baptista, R; Horne, K; Hubeny, I; Rutten, R G M

    1998-01-01

    [abridged abstract] We present and analyze Hubble Space Telescope observations of the eclipsing nova-like cataclysmic variable UX UMa obtained with the Faint Object Spectrograph. Two eclipses each were observed with the G160L grating (covering the ultraviolet waveband) in August of 1994 and with the PRISM (covering the near-ultraviolet to near-infrared) in November of the same year. The system was 50% brighter in November than in August, which, if due to a change in the accretion rate, indicates a fairly substantial increase in Mdot_acc by >~ 50%. Model disk spectra constructed as ensembles of stellar atmospheres provide poor descriptions of the observed post-eclipse spectra, despite the fact that UX UMa's light should be dominated by the disk at this time. Suitably scaled single temperature model stellar atmospheres with T_eff = 12,500-14,500 K actually provide a better match to both the ultraviolet and optical post-eclipse spectra. Evidently, great care must be taken in attempts to derive accretion rates fr...

  14. WZ Sge: An eclipsing cataclysmic variable evolving towards the period minimum

    Science.gov (United States)

    Han, Z.-T.; Qian, S.-B.; Voloshina, Irina; Zhu, L.-Y.

    2017-10-01

    We present the photometric results of the eclipsing cataclysmic variable (CV) WZ Sge near the period minimum (Pmin). Eight new mid-eclipse times were determined and the orbital ephemeris was updated. Our result shows that the orbital period of WZ Sge is decreasing at a rate of P˙ = - 2.72(± 0.23) ×10-13 ss-1 . This secular decrease, coupled with previous detection of its donor, suggest that WZ Sge is a pre-bounce system. Further analysis indicates that the observed period decrease rate is about 1.53 times higher than pure gravitational radiation (GR) driving. We constructed the evolutionary track of WZ Sge, which predicts that Pmin of WZ Sge is ∼ 77.98(± 0.90) min. If the orbital period decreases at the current rate, WZ Sge will evolve past its Pmin after ∼ 25.3 Myr. Based on the period evolution equation we find M˙2 ≃ 4.04(± 0.10) ×10-11M⊙ yr-1 , which is compatible with the current concept of CV evolution at ultrashort orbital periods.

  15. An investigation of a magnetic cataclysmic variable with a period of 14.1 ks

    CERN Document Server

    Wang, Song; Zhang, Chuan-peng; Liu, Ji-feng

    2016-01-01

    Magnetic cataclysmic variables (CVs) contain a white dwarf with magnetic field strong enough to control the accretion flow from a late type secondary. In this paper, we discover a magnetic CV (CXOGSG J215544.4+380116) from the $Chandra$ archive data. The X-ray light curves show a significant period of 14.1 ks, and the X-ray spectra can be described by a multi-temperature hot thermal plasma, suggesting the source as a magnetic CV. The broad dip in the X-ray light curve is due to the eclipse of the primary magnetic pole, and the additional dip in the bright phase of the soft and medium bands may be caused by the accretion stream crossing our line of sight to the primary pole. Follow-up optical spectra show features of an M2--M4 dwarf dominating the red band and a WD which is responsible for the weak upturn in the blue band. The mass ($\\sim$ 0.4 $M_{\\odot}$) and radius ($\\sim$ 0.4 $R_{\\odot}$) for the M dwarf are obtained using CV evolution models and empirical relations between the orbital period and the mass/r...

  16. The space density of cataclysmic variables: constraints from the ROSAT North Ecliptic Pole Survey

    CERN Document Server

    Pretorius, M L; O'Donoghue, D; Henry, J P; Gioia, I M; Mullis, C R

    2007-01-01

    We use the ROSAT North Ecliptic Pole (NEP) survey to construct a small, but purely X-ray flux-limited sample of cataclysmic variable stars (CVs). The sample includes only 4 systems, 2 of which (RX J1715.6+6856 and RX J1831.7+6511) are new discoveries. We present time-resolved spectroscopy of the new CVs and measure orbital periods of 1.64 \\pm 0.02 h and 4.01\\pm 0.03 h for RX 1715.6+6856 and RX J1831.7+6511, respectively. We also estimate distances for all the CVs in our sample, based mainly on their apparent brightness in the infrared. The space density of the CV population represented by our small sample is (1.1 +2.3/-0.7) 10^-5 pc^-3. We can also place upper limits on the space density of any sub-population of CVs too faint to be included in the NEP survey. In particular, we show that if the overall space density of CVs is as high as 2 10^-4 pc^-3 (as has been predicted theoretically), the vast majority of CVs must be fainter than L_X \\simeq 2 10^29 erg/s.

  17. Evolution of Cataclysmic Variables and Related Binaries Containing a White-Dwarf

    CERN Document Server

    Kalomeni, B; Rappaport, S; Molnar, M; Quintin, J; Yakut, K

    2016-01-01

    We present a binary evolution study of cataclysmic variables (CVs) and related systems with white dwarf accretors, including for example, AM CVn systems, classical novae, supersoft X-ray sources, and systems with giant donor stars. Our approach intentionally avoids the complications associated with population synthesis algorithms thereby allowing us to present the first truly comprehensive exploration of all of the subsequent binary evolution pathways that ZACVs might follow (assuming fully non-conservative, Roche-lobe overflow onto an accreting WD) using the sophisticated binary stellar evolution code MESA. The grid consists of 56,000 initial models, including 14 white dwarf accretor masses, 43 donor-star masses ($0.1-4.7$ $M_{\\odot}$), and 100 orbital periods. We explore evolution tracks in the orbital period and donor-mass ($P_{\\rm orb}-M_{\\rm don}$) plane in terms of evolution dwell times, masses of the white dwarf accretor, accretion rate, and chemical composition of the center and surface of the donor s...

  18. PHL 1445: An eclipsing cataclysmic variable with a substellar donor near the period minimum

    CERN Document Server

    McAllister, M J; Baraffe, I; Dhillon, V S; Marsh, T R; Bento, J; Bochinski, J; Bours, M C P; Breedt, E; Copperwheat, C M; Hardy, L K; Kerry, P; Parsons, S G; Rostron, J W; Sahman, D I; Savoury, C D J; Tunnicliffe, R L

    2015-01-01

    We present high-speed, three-colour photometry of the eclipsing dwarf nova PHL 1445, which, with an orbital period of 76.3 min, lies just below the period minimum of ~82 min for cataclysmic variable stars. Averaging four eclipses reveals resolved eclipses of the white dwarf and bright spot. We determined the system parameters by fitting a parameterised eclipse model to the averaged lightcurve. We obtain a mass ratio of q = 0.087 +- 0.006 and inclination i = 85.2 +- 0.9 degrees. The primary and donor masses were found to be Mw = 0.73 +- 0.03 Msun and Md = 0.064 +- 0.005 Msun, respectively. Through multicolour photometry a temperature of the white dwarf of Tw = 13200 +- 700 K and a distance of 220 +- 50 pc were determined. The evolutionary state of PHL 1445 is uncertain. We are able to rule out a significantly evolved donor, but not one that is slightly evolved. Formation with a brown dwarf donor is plausible; though the brown dwarf would need to be no older than 600 Myrs at the start of mass transfer, requirin...

  19. Long-term Accretion Variations of the Magnetic Cataclysmic Variable Star QQ Vulpecula

    Science.gov (United States)

    Cooper Rose, Sanaea; Kafka, Stella; Jorgenson, Regina; Carr, Derrick; Childs, Francesca; Christenson, Holly; Karim, Md. Tanveer; Konchady, Tarini; Walker, Gary E.; Honeycutt, R. K.

    2017-01-01

    Magnetic cataclysmic variable stars have brightness variations that repeat with each revolution of the two stars about the center of mass of the system. However, in the case of QQ Vulpecula (QQ Vul), this brightness variation pattern changes in the long term. This study makes use of two decades worth of data from the Roboscope Telescope as well as data from the American Association of Variable Star Observers (AAVSO) database to examine the long-term evolution of QQ Vul’s phase curves. Nightly observations using the Maria Mitchell Association's Vestal and Loines Observatories supplemented this analysis by clarifying short-term brightness variation. The long-term data was divided into four commonly observed behavioral types ranging from a double peaked curve of ~15.5 magnitude to a ~15.0 magnitude curve that had a primary minimum and a slow, linear rise in brightness in place of the secondary minimum. The nightly data kept within the confines of these categories, though the secondary minimum in the nightly data never vanished. No periodicity was found in the long-term variations. The model often invoked to explain the double peaked curve consists of single pole accretion in which a partial self-eclipse causes the secondary minimum and cyclotron beaming causes the primary minimum. However, the long-term variation may indicate a changing accretion rate, which may manifest itself in changes to the shape, size, or location of the accretion spot on the white dwarf such that it lessens or removes the secondary minimum. This project was supported by the NSF REU grant AST-1358980, the Massachusetts Space Grant, and the Nantucket Maria Mitchell Association.

  20. NON-THERMAL EMISSION FROM CATACLYSMIC VARIABLES: IMPLICATIONS ON ASTROPARTICLE PHYSICS

    Directory of Open Access Journals (Sweden)

    Vojtech Šimon

    2013-12-01

    Full Text Available We review the lines of evidence that some cataclysmic variables (CVs are the sources of non-thermal radiation. It was really observed in some dwarf novae in outburst, a novalike CV in the high state, an intermediate polar, polars, and classical novae (CNe during outburst. The detection of this radiation suggests the presence of highly energetic particles in these CVs. The conditions for the observability of this emission depend on the state of activity, and the system parameters. We review the processes and conditions that lead to the production of this radiation in various spectral bands, from gamma-rays including TeV emission to radio. Synchrotron and cyclotron emissions suggest the presence of strong magnetic fields in CV. In some CVs, e.g. during some dwarf nova outbursts, the magnetic field generated in the accretion disk leads to the synchrotron jets radiating in radio. The propeller effect or a shock in the case of the magnetized white dwarf (WD can lead to a strong acceleration of the particles that produce gamma-ray emission via pi0 decay; even Cherenkov radiation is possible. In addition, a gamma-ray production via pi0 decay was observed in the ejecta of an outburst of a symbiotic CN. Nuclear reactions during thermonuclear runaway in the outer layer of the WD undergoing CN outburst lead to the production of radioactive isotopes; their decay is the source of gamma-ray emission. The production of accelerated particles in CVs often has episodic character with a very small duty cycle; this makes their detection and establishing the relation of the behavior in various bands difficult.

  1. Effective temperatures of cataclysmic-variable white dwarfs as a probe of their evolution

    Science.gov (United States)

    Pala, A. F.; Gänsicke, B. T.; Townsley, D.; Boyd, D.; Cook, M. J.; De Martino, D.; Godon, P.; Haislip, J. B.; Henden, A. A.; Hubeny, I.; Ivarsen, K. M.; Kafka, S.; Knigge, C.; LaCluyze, A. P.; Long, K. S.; Marsh, T. R.; Monard, B.; Moore, J. P.; Myers, G.; Nelson, P.; Nogami, D.; Oksanen, A.; Pickard, R.; Poyner, G.; Reichart, D. E.; Rodriguez Perez, D.; Schreiber, M. R.; Shears, J.; Sion, E. M.; Stubbings, R.; Szkody, P.; Zorotovic, M.

    2017-04-01

    We present HST spectroscopy for 45 cataclysmic variables (CVs), observed with HST/COS and HST/STIS. For 36 CVs, the white dwarf is recognisable through its broad Ly α absorption profile and we measure the white dwarf effective temperatures (Teff) by fitting the HST data assuming log g = 8.35, which corresponds to the average mass for CV white dwarfs (≃0.8 M⊙). Our results nearly double the number of CV white dwarfs with an accurate temperature measurement. We find that CVs above the period gap have, on average, higher temperatures ( ≃ 23 000 K) and exhibit much more scatter compared to those below the gap ( ≃ 15 000 K). While this behaviour broadly agrees with theoretical predictions, some discrepancies are present: (i) all our new measurements above the gap are characterized by lower temperatures (Teff ≃ 16 000-26 000 K) than predicted by the present-day CV population models (Teff ≃ 38 000-43 000 K); (ii) our results below the gap are not clustered in the predicted narrow track and exhibit in particular a relatively large spread near the period minimum, which may point to some shortcomings in the CV evolutionary models. Finally, in the standard model of CV evolution, reaching the minimum period, CVs are expected to evolve back towards longer periods with mean accretion rates dot{M}≲ 2 × 10^{-11} M_{⊙} yr^{-1}, corresponding to Teff ≲ 11 500 K. We do not unambiguously identify any such system in our survey, suggesting that this major component of the predicted CV population still remains elusive to observations.

  2. The long-term light curve of the cataclysmic variable V794 Aquilae

    Energy Technology Data Exchange (ETDEWEB)

    Honeycutt, R. K. [Astronomy Department, Indiana University, Swain Hall West, Bloomington, IN 47405 (United States); Kafka, S. [Department of Terrestrial Magnetism, Carnegie Inst. of Washington, 5241 Broad Branch Road NW, Washington, DC 20015 (United States); Robertson, J. W., E-mail: honey@astro.indiana.edu, E-mail: skafka@aip.org, E-mail: Jeff.Robertson@atu.edu [Arkansas Tech University, Department of Physical Sciences, 1701 N. Boulder, Russellville, AR 72801-2222 (United States)

    2014-01-01

    The 1990-2012 light curve of the nova-like (NL) cataclysmic variable V794 Aql is studied in order to characterize and better understand the transitions to and from the faint state, and the variations within the bright state. Investigations of earlier portions of this data had concluded that the transitions to the low state were much slower than the rapid recovery, giving a sawtoothed appearance to the light curve. This behavior differs from that of most other VY Scl stars, which led to an interpretation of the large amplitude sawtooths as being due to an accretion disk (AD) instability. However, more recent photometry strongly suggests that the bright state itself has transitions of 1-1.5 mag, and that earlier studies had intermixed these bright state variations with the transitions to the low state. These newly recognized variations within the bright state sometimes appear as small outbursts (OBs) with typical amplitudes of 0.5-1.5 mag and spacings of ∼15-50 days. The rise times of the OBs are 2-3 times faster than the decline times. We argue that the V794 Aql bright state variations are due to AD behavior similar to that seen in dwarf novae, but with varying degrees of stability. Similar regular small OBs have also been reported in other NL CVs, which we compare with V794 Aql. The true deep low states in V794 Aql appear to be normal, having transition speeds and shapes very similar to the transitions in other VY Scl stars.

  3. Physical parameters and orbital period variation of a newly discovered cataclysmic variable GSC 4560–02157

    Science.gov (United States)

    Han, Zhong-Tao; Qian, Sheng-Bang; Voloshina, Irina; Metlov, Vladimir G.; Zhu, Li-Ying; Li, Lin-Jia

    2016-10-01

    GSC 4560–02157 is a new eclipsing cataclysmic variable with an orbital period of 0.265359 days. By using the published V ‑ and R ‑ band data together with our observations, we discovered that the O ‑ C curve of GSC 4560–02157 may show a cyclic variation with a period of 3.51 years and an amplitude of 1.40 min. If this variation is caused by a light travel-time effect via the existence of a third body, then its mass can be derived as M 3 sin i' ≈ 91.08 M Jup, and it should be a low-mass star. In addition, several physical parameters were measured. The color of the secondary star was determined to be V ‑ R = 0.77(±0.03) which corresponds to a spectral type of K2–3. The secondary star's mass was estimated as M 2 = 0.73(±0.02) M ⊙ by combing the derived V ‑ R value around phase 0 with the assumption that it obeys the mass-luminosity relation for main sequence stars. This mass is consistent with the mass—period relation for CV donor stars. For the white dwarf, the eclipse durations and contacts of the white dwarf yield an upper limit on the white dwarf's radius corresponding to a lower limit on mass of M 1 ≈ 0.501 M ⊙. The overestimated radius and previously published spectral data indicate that the boundary layer may have a very high temperature.

  4. Interferometric Astrometry with Hubble Space Telescope Fine Guidance Sensor 3 The Parallax of the Cataclysmic Variable TV Columbae

    CERN Document Server

    McArthur, B E; Lee, J; Van Altena, W F; Slesnick, C L; Rhee, J T; Patterson, R J; Fredrick, L W; Spiesman, W J; Nelan, E; Duncombe, R L; Hemenway, P D; Jefferys, W H; Shelus, P J; Franz, O G; Wasserman, L H

    2001-01-01

    TV Columbae (TV Col) is a 13th magnitude Intermediate Polar (IP) Cataclysmic Variable (CV), with multiple periods found in the light curves. Past estimates predicted a distance of 400 parsec to greater than 500 parsec. Recently completed Hubble Space Telescope (HST) Fine Guidance Sensor (FGS) interferometric observations allow us to determine the first trigonometric parallax to TV Col. This determination puts the distance of TV Col at 368 -15+17 parsecs. CD-32 2376, a 10th magnitude Tycho Catalog star, is a reference star in the TV Col frame. We find a distance of $127.7 -1+1 parsecs.

  5. 1H 1752 + 081: an eclipsing cataclysmic variable with a small accretion disk

    Science.gov (United States)

    Silber, Andrew D.; Remillard, Ronald A.; Horne, Keith; Bradt, Hale V.

    1994-04-01

    We announce the discovery of an eclipsing nova-like cataclysmic variable (CV) as the optical counterpart to the HEAO 1 X-ray source 1H1752 + 081. This CV has an orbital period of 1.882801 hr, a high equivalent width of H-beta, and an average mv of 16.4 out of the eclipse. A geometric model is constructed from observations of the eclipse ingress and egress in many optical bandpasses. The broad-band emission originates primarily in two regions; the disk/accretion stream 'hot spot' and a compact central component, which may be a spot on the white dwarf surface, the entire white dwarf surface or the boundary layer between the accretion disk and the white dwarf surface. Based on the durations and offsets of the two eclipses we determined the mass ratio q = 2.5 +/- 0.6 and the angle of inclination i = 77 deg +/- 2 deg. If the central component is the entire white dwarf surface the masses of the stars are M1 = 0.80 +/- 0.06 solar masses and M2 = 0.32 +/- 0.06 solar masses. The disk is faint and small (RD = 0.25 +/- 0.05 rL1, where rL1 is the distance from the primary to the L1 point), compared to other eclipsing CVs. The small disk may result from the removal of angular momentum from the accretion disk by the magnetic field of the white dwarf; this CV may be a DQ Her type with a slowly rotating white dwarf. The emission-line velocities do not show the 'Z-wave' expected from the eclipse of a Keplerian accretion disk, nor do they have the correct phasing to originate near the white dwarf. The most likely origin of the line emission is the hot spot. The secondary star is visible at wavelengths greater than or equal to 6000 A during eclipse. We estimate a spectral type approximately M6 which, together with the observed m1 = 16.94 during eclipse, results in a distance estimate of 150 +/- 27 pc.

  6. Hubble Space Telescope Eclipse Observations of the Nova Like Cataclysmic Variable UX Ursae Majoris

    Science.gov (United States)

    Knigge, Christian; Long, Knox S.; Wade, Richard A.; Baptista, Raymundo; Horne, Keith; Hubeny, Ivan; Rutten, Rene G. M.

    1998-01-01

    We present and analyze Hubble Space Telescope observations of the eclipsing nova-like cataclysmic variable UX UMa obtained with the Faint Object Spectrograph. Two eclipses each were observed with the G160L grating (covering the ultraviolet waveband) in 1994 August and with the PRISM (covering the near-ultraviolet to near-infrared) in November of the same year. The system was about 50% brighter in November than in August, which, if due to a change in the accretion rate, indicates a fairly substantial increase in Mass accretion by about 50%. The eclipse light curves are qualitatively consistent with the gradual occultation of an accretion disk with a radially decreasing temperature distribution. The light curves also exhibit asymmetries about mideclipse that are likely due to a bright spot at the disk edge. Bright-spot spectra have been constructed by differencing the mean spectra observed at pre- and posteclipse orbital phases. These difference spectra contain ultraviolet absorption lines and show the Balmer jump in emission. This suggests that part of the bright spot may be optically thin in the continuum and vertically extended enough to veil the inner disk and/or the outflow from UX UMa in some spectral lines. Model disk spectra constructed as ensembles of stellar atmospheres provide poor descriptions of the observed posteclipse spectra, despite the fact that UX UMa's light should be dominated by the disk at this time. Suitably scaled single temperature model stellar atmospheres with T(sub eff) approximately equals 12,500-14,500 K actually provide a better match to both the ultraviolet and optical posteclipse spectra. Evidently, great care must be taken in attempts to derive accretion rates from comparisons of disk models to observations. One way to reconcile disk models with the observed posteclipse spectra is to postulate the presence of a significant amount of optically thin material in the system. Such an optically thin component might be associated with the

  7. VizieR Online Data Catalog: Radial velocities of 35 cataclysmic variables (Thorstensen+, 2016)

    Science.gov (United States)

    Thorstensen, J. R.; Alper, E. H.; Weil, K. E.

    2017-02-01

    We present spectroscopic follow-up observations of 35 newly discovered cataclysmic variables (CVs), 32 of which were found by the Catalina Real Time Transient Surveys (CRTS; Drake et al. 2009, Cat. J/ApJ/696/870; Drake et al. 2014, Cat. J/MNRAS/441/1186; Breedt et al. 2014, Cat. J/MNRAS/443/3174), ASAS-SN (Shappee et al. 2014ApJ...788...48S), and/or MASTER (Lipunov et al. 2010AdAst2010E..30L). All our observations are from Michigan-Dartmouth-MIT (MDM) Observatory on Kitt Peak, Arizona. For nearly all the spectra, we used the "modspec" spectrograph (a description of the modspec can be found at http://mdm.kpno.noao.edu/Manuals/ModSpec/modspec_man.html) with a 600line/mm grating. We mostly used a SITe 20482 CCD detector, which yielded 2Å/pixel from 4210 to 7500Å, with declining throughput toward the ends of the spectral range. When this detector was unavailable, we used a very similar 10242 SITe detector ("Templeton"), which covered 4660 to 6730Å. The modspec was mounted mostly on the 2.4m Hiltner telescope, but for some of the brighter objects, we used the 1.3m McGraw-Hill telescope. For a few of the 1.3m spectra, we used the Mark III grism spectrograph, which covered 4580 to 6850Å at 2.3Å/pixel. On both telescopes and with both spectrographs, we used an Andor Ikon camera to view the reflective slit jaws through a microscope and guided the telescope with a separate off-axis guider. With this arrangement we could place any object that was bright enough for a usable spectrum in the slit and track it accurately even if the portion of the light spilling onto the slit jaws was invisible. Our emission-line radial velocities are almost entirely of Hα, since it almost always gives the best signal-to-noise ratio with our instrument. (3 data files).

  8. Mind the Gap when Data Mining the Ritter-Kolb Cataclysmic Variable Catalogue

    Science.gov (United States)

    Sparks, Warren M.; Sion, Edward M.

    2017-01-01

    The cataclysmic variable (CV) binary consists of a white dwarf primary and a low-mass secondary which overflows its Roche lobe. The Ritter-Kolb catalogue (2003, A&A, 404, 301) is a collection (~1000) of CV binaries and related objects. We have mined this catalogue for CVs with unevolved secondaries whose mass ratio (secondary/primary) is known (~130). A plot of the secondary mass verses the log of the orbital period exhibits the well-known period gap at 2-3 hrs. In addition, this plot shows that the secondary masses just above the period gap are collectively much larger than those just below. The average of the first ten secondary masses above the period is 180% larger than the average below the gap.The disrupted magnetic braking hypothesis (Howell, Nelson, and Rappaport 2001, ApJ, 550, 897 [HNR]) predicts that when the secondary becomes fully convective, the magnetic braking, which has driven the secondary out of thermal equilibrium, stops. In adjusting to thermal equilibrium the secondary shrinks below its Roche lobe and no longer loses mass. The binary system ceases to appear as a CV until gravitational radiation loss brings the secondary back in contact with its Roche lobe. This scenario is at odds with the apparent secondary mass loss across the period gap. Either the secondary continues to lose mass while crossing the period gap or the secondary masses are miscalculated!Magnetic braking causes the secondary to expand or inflate larger than its single star counterpart. Any orbital parameter calculation which assumes a radius-mass relationship based on single main-sequence stars will overestimate the mass of the secondary. We can approximate this mass overestimation from calculations by HNR which take into account the thermal heating from magnetic braking. Using this approximation as a first-order correction to the secondary mass, we replot the deflated secondary mass versus the binary period. The deflated masses immediately above and below the period gap are

  9. Archival Ultraviolet Spectroscopic Analysis of Disk-Dominated Cataclysmic Variables: The Importance of the Boundary Layer

    Science.gov (United States)

    Godon, Patrick

    We propose to carry out a systematic ultraviolet (UV) spectral analysis of 43 disk- dominated systems in cataclysmic variable (CV) binaries with the inclusion of the contribution from the boundary layer, from NASA UV Space Missions such as HST, FUSE, HUT, IUE and ORFEUS. The mass accretion in CVs is a badly needed parameter to verify the theory of the evolution of CVs, to understand the accretion process itself and the disk instability. However, many disk-dominated systems unexpectedly prove impossible to model using only standard accretion disks and white dwarfs in combination. Our objective is to overcome this difficulty by modeling the UV spectrum of the boundary layer between the star and disk, including its effect on the spectrum of the disk and star for the first time. This will provide the first step needed for the improvement of the disk model in UV spectroscopic analysis of disk-dominated systems in CVs. At the same time the results of this spectral analysis will provide information on the boundary layer and accretion disk of these systems. As a by-product, we will create a web-based catalog of all the archival UV spectra of disk-dominated CVs, which will be added and fused to our existing and growing web-based catalog of FUSE spectra of CVs. Since the WD is the most common end-product of stellar evolution (approx 90% of all the stars in the Galaxy have or will evolve into white dwarfs), and the accretion disk is the most common universal structure resulting from mass transfer with angular momentum, and since both can be directly viewed in CVs in the ultraviolet (UV), an understanding of the consequences of accretion in these systems is the first step in a global understanding of accretion in other systems throughout the universe. These include Young Stellar Objects, galactic binaries (accretion onto neutron stars and black holes) and the most difficult to study, Active Galactic Nuclei. In addition, the formation history of WDs is closely linked to the

  10. The space density and X-ray luminosity function of non-magnetic cataclysmic variables

    Science.gov (United States)

    Pretorius, Magaretha L.; Knigge, Christian

    2012-01-01

    We combine two complete, X-ray flux-limited surveys, the ROSAT Bright Survey (RBS) and the ROSAT North Ecliptic Pole (NEP) survey, to measure the space density (ρ) and X-ray luminosity function (Φ) of non-magnetic cataclysmic variables (CVs). The combined survey has a flux limit of FX≳ 1.1 × 10-12 erg cm-2 s-1 over most of its solid angle of just over ?, but is as deep as ≃10-14 erg cm-2 s-1 over a small area. The CV sample that we construct from these two surveys contains 20 non-magnetic systems. We carefully include all sources of statistical error in calculating ρ and Φ by using Monte Carlo simulations; the most important uncertainty proves to be the often large errors in distances estimates. If we assume that the 20 CVs in the combined RBS and NEP survey sample are representative of the intrinsic population, the space density of non-magnetic CVs is ?. We discuss the difficulty in measuring Φ in some detail - in order to account for biases in the measurement, we have to adopt a functional form for Φ. Assuming that the X-ray luminosity function of non-magnetic CVs is a truncated power law, we constrain the power-law index to -0.80 ± 0.05. It seems likely that the two surveys have failed to detect a large, faint population of short-period CVs, and that the true space density may well be a factor of 2 or 3 larger than what we have measured; this is possible, even if we only allow for undetected CVs to have X-ray luminosities in the narrow range 28.7 log(LX/erg s-1) < 29.7. However, ρ as high as 2 × 10-4 pc-3 would require that the majority of CVs has X-ray luminosities below LX= 4 × 1028 erg s-1 in the 0.5-2.0 keV band.

  11. New Close Binary Systems from the SDSS-I (Data Release Five) and the Search for Magnetic White Dwarfs in Cataclysmic Variable Progenitor Systems

    CERN Document Server

    Silvestri, Nicole M; Hawley, Suzanne L; West, Andrew A; Schmidt, Gary D; Liebert, James; Szkody, Paula; Mannikko, Lee; Wolfe, Michael A; Barentine, J C; Brewington, Howard J; Harvanek, Michael; Krzesinski, Jurik; Long, Dan; Schneider, Donald P; Snedden, Stephanie A

    2007-01-01

    We present the latest catalog of more than 1200 spectroscopically-selected close binary systems observed with the Sloan Digital Sky Survey through Data Release Five. We use the catalog to search for magnetic white dwarfs in cataclysmic variable progenitor systems. Given that approximately 25% of cataclysmic variables contain a magnetic white dwarf, and that our large sample of close binary systems should contain many progenitors of cataclysmic variables, it is quite surprising that we find only two potential magnetic white dwarfs in this sample. The candidate magnetic white dwarfs, if confirmed, would possess relatively low magnetic field strengths (B_WD < 10 MG) that are similar to those of intermediate-Polars but are much less than the average field strength of the current Polar population. Additional observations of these systems are required to definitively cast the white dwarfs as magnetic. Even if these two systems prove to be the first evidence of detached magnetic white dwarf + M dwarf binaries, th...

  12. Anomalous ultraviolet line flux ratios in the cataclysmic variables 1RXSJ232953.9+062814, CE315, BZ UMa and EY Cyg observed with HST/STIS

    CERN Document Server

    Gänsicke, B T; De Martino, D; Beuermann, K; Long, K S; Sion, E M; Knigge, C; Marsh, T; Hubeny, I; G\\"ansicke, Boris T.; Szkody, Paula; Martino, Domitilla de; Beuermann, Klaus; Long, Knox S.; Sion, Edward M.; Knigge, Christian; Marsh, Tom; Hubeny, Ivan

    2003-01-01

    Brief HST/STIS spectroscopic snapshot exposures of the cataclysmic variables 1RXSJ232953.9+062814, CE315, BZ UMa and EY Cyg reveal very large NV/CIV line flux ratios, similar to those observed in AE Aqr. Such anomalous line flux ratios have so far been observed in 10 systems, and presumably reflect a different composition of the accreted material compared to the majority of cataclysmic variables. We discuss the properties of this small sample in the context of the recent proposal by Schenker et al. (2002) that a significant fraction of the present-day population of cataclysmic variables may have passed through a phase of thermal time-scale mass transfer.

  13. A Far-Ultraviolet Survey of 47 Tucanae.II The Long-Period Cataclysmic Variable AKO 9

    CERN Document Server

    Knigge, C; Shara, M M; Long, K S; Gilliland, R L; Knigge, Christian; Zurek, David. R.; Shara, Michael M.; Long, Knox S.; Gilliland, Ronald L.

    2003-01-01

    We present time-resolved, far-ultraviolet (FUV) spectroscopy and photometry of the 1.1 day eclipsing binary system AKO 9 in the globular cluster 47 Tucanae. AKO 9's FUV spectrum is blue and exhibits prominent C IV and He II emission lines. The spectrum broadly resembles that of long-period, cataclysmic variables in the galactic field. Combining our time-resolved FUV data with archival optical photometry of 47 Tuc, we refine AKO 9's orbital period and define an accurate ephemeris for the system. We also place constraints on several other system parameters, using a variety of observational constraints. We find that all of the empirical evidence is consistent with AKO 9 being a long-period dwarf nova in which mass transfer is driven by the nuclear expansion of a sub-giant donor star. We therefore conclude that AKO 9 is the first spectroscopically confirmed cataclysmic variable in 47 Tuc. We also briefly consider AKO 9's likely formation and ultimate evolution. Regarding the former, we find that the system was al...

  14. Full 3-D MHD calculations of accretion flow Structure in magnetic cataclysmic variable stars with strong and complex magnetic fields

    CERN Document Server

    Zhilkin, A G; Mason, P A; 10.1134/S1063772912040087

    2012-01-01

    We performed 3D MHD calculations of stream accretion in cataclysmic variable stars for which the white dwarf primary star possesses a strong and complex magnetic field. These calculations are motivated by observations of polars; cataclysmic variables containing white dwarfs with magnetic fields sufficiently strong to prevent the formation of an accretion disk. So an accretion stream flows from the L1 point and impacts directly onto one or more spots on the surface of the white dwarf. Observations indicate that the white dwarf, in some binaries, possesses a complex (non-dipolar) magnetic field. We perform simulations of 10 polars or equivalently one asynchronous polar at 10 different beat phases. Our models have an aligned dipole plus quadrupole magnetic field centered on the white dwarf primary. We find that for a sufficiently strong quadrupole component an accretion spot occurs near the magnetic equator for slightly less than half of our simulations while a polar accretion zone is active for most of the rest...

  15. Cataclysmic Variables and Other Compact Binaries in the Globular Cluster NGC 362: Candidates from Chandra and HST

    CERN Document Server

    Margon, Bruce; Homer, L; Pooley, D; Bassa, C G; Anderson, S F; Lewin, W H G; Verbunt, F; Kong, A K H; Plotkin, R M

    2010-01-01

    Highly sensitive and precise X-ray imaging from Chandra, combined with the superb spatial resolution of HST optical images, dramatically enhances our empirical understanding of compact binaries such as cataclysmic variables and low mass X-ray binaries, their progeny, and other stellar X-ray source populations deep into the cores of globular clusters. Our Chandra X-ray images of the globular cluster NGC 362 reveal 100 X-ray sources, the bulk of which are likely cluster members. Using HST color-magnitude and color-color diagrams, we quantitatively consider the optical content of the NGC 362 Chandra X-ray error circles, especially to assess and identify the compact binary population in this condensed-core globular cluster. Despite residual significant crowding in both X-rays and optical, we identify an excess population of H{\\alpha}-emitting objects that is statistically associated with the Chandra X-ray sources. The X-ray and optical characteristics suggest that these are mainly cataclysmic variables, but we al...

  16. Structure of accretion flows in nova-like cataclysmic variables: RW Sextantis and 1RXS J064434.5+334451

    Science.gov (United States)

    Hernandez, M. S.; Zharikov, S.; Neustroev, V.; Tovmassian, G.

    2017-09-01

    New time-resolved optical spectroscopic echelle observations of the nova-like cataclysmic variable RW Sextantis were obtained, with the aim of studying the properties of emission features in the system. The profile of the H α emission line can be clearly divided into two ('narrow' and 'wide') components. Similar emission profiles are observed in another nova-like system, 1RXS J064434.5+33445, for which we also reanalysed the spectral data and redetermined the system parameters. The source of the 'narrow', low-velocity component is the irradiated face of the secondary star. We disentangled and removed the 'narrow' component from the H α profile to study the origin and structure of the region emitting the wide component. We found that the 'wide' component is not related to the white dwarf or the wind from the central part of the accretion disc, but is emanated from the outer side of the disc. Inspection of literature on similar systems indicates that this feature is common for some other long-period nova-like variables. We propose that the source of the 'wide' component is an extended, low-velocity region in the outskirts of the opposite side of the accretion disc, with respect to the collision point of the accretion stream and the disc.

  17. Multi-band study of a new asynchronous magnetic cataclysmic variable and a flaring X-ray source

    CERN Document Server

    Rea, N; Esposito, P; D'Avanzo, P; de Martino, D; Israel, G L; Torres, D F; Campana, S; Belloni, T M; Papitto, A; Masetti, N; Carrasco, L; Possenti, A; Wieringa, M; Wilhelmi, E De Ona; Li, J; Bozzo, E; Ferrigno, C; Linares, M; Tauris, T M; Hernanz, M; Ribas, I; Monelli, M; Borghese, A; Baglio, M C; Casares, J

    2016-01-01

    In search for the counterpart to the Fermi-LAT source 3FGL J0838.8-2829, we report on 1) a new magnetic Cataclysmic Variable (mCV), RX J0838-2827, that we identify as an asynchronous system (therefore not associated with this Fermi-LAT source) and 2) on a new X-ray flaring source, XMM J083850.4-282759, that might be tentatively identified as new candidate Transitional Millisecond Pulsar, possibly associated with the gamma-ray source. We observed the field in the X-ray band with Swift, twice with XMM-Newton, as well as performed infrared, optical (with OAGH, ESO-NTT and IAC80) and radio (ATCA) observations, and we report on archival INTEGRAL observations. RX J0838-2827 is extremely variable in the X-ray and optical bands, and timing analysis reveals the presence of several periodicities modulating its X-ray and optical emission. The most evident modulations are interpreted as due to the binary system orbital period of ~1.64hr and the white dwarf spin period of ~1.47hr. Furthermore, a strong flux modulation at ...

  18. On the evolution of accretion disc flow in cataclysmic variables. III - Outburst properties of constant and uniform-alpha model discs

    Science.gov (United States)

    Lin, D. N. C.; Faulkner, J.; Papaloizou, J.

    1985-01-01

    Attention is given to the stability and evolution of some simple accretion disk models in which the viscosity is prescribed by an ad hoc, uniform-alpha model. Emphasis is placed on systems in which the mass input rate from the secondary to the disk around the primary is assumed to be constant, although initial calculations with variable mass input rates are also performed. Time-dependent visual magnitude light curves constructed for cataclysmic binaries with a range of disk size, primary mass and mass input rate, and viscosity magnitude, are compared with the observed properties of various cataclysmic variable subclasses. The results obtained indicate that the observational differences between novae and dwarf novae may be due to mass input rate differences. The present models can reproduce the gross observational features of U-Gem-type dwarf nova outbursts.

  19. Unambiguous Detection of Reflection in Magnetic Cataclysmic Variables: Joint NuSTAR-XMM-Newton Observations of Three Intermediate Polars

    CERN Document Server

    Mukai, Koji; Bernardini, Federico; de Martino, Domitilla

    2015-01-01

    In magnetic cataclysmic variables (CVs), X-ray emission regions are located close to the white dwarf surface, which is expected to reflect a significant fraction of intrinsic X-rays above 10 keV, producing a Compton reflection hump. However, up to now, a secure detection of this effect in magnetic CVs has largely proved elusive because of the limited sensitivity of non-imaging X-ray detectors. Here we report our analysis of joint NuSTAR/XMM-Newton observations of three magnetic CVs, V709 Cas, NY Lup, and V1223 Sgr. The improved hard X-ray sensitivity of the imaging NuSTAR data has resulted in the first robust detection of Compton hump in all three objects, with amplitudes of ~1 or greater in NY Lup, and likely <1.0 in the other two. We also confirm earlier report of a strong spin modulation above 10 keV in V709 Cas, and report the first detection of small spin amplitudes in the others. We interpret this as due to different height of the X-ray emitting region among these objects. A height of ~0.2 white dwar...

  20. 1RXSJ173021.5-055933: a cataclysmic variable with a fast-spinning magnetic white dwarf

    CERN Document Server

    De Martino, D; Mukai, K; Bonnet-Bidaud, J -M; Falanga, M; Gänsicke, B T; Haberl, F; Marsh, T R; Mouchet, M; Littlefair, S P; Dhillon, V

    2008-01-01

    We present the first X-ray observations with the XMM-Newton and INTEGRAL satellites of the recently discovered cataclysmic variable 1RXSJ173021.5-055933, together with simultaneous UV and coordinated optical photometry aiming at characterising its broad-band temporal and spectral properties and classifying this system as a magnetic one. We find that the X-ray light curve is dominated by the 128s spin period of the accreting white dwarf in contrast to the far-UV range, which turns out to be unmodulated at a 3sigma level. Near-UV and optical pulses are instead detected at twice the spin frequency. We identify the contributions from two accreting poles that imply a moderately inclined dipole field allowing, one pole to dominate at energies at least up to 10keV, and a secondary that instead is negligible above 5keV. X-ray spectral analysis reveals the presence of multiple emission components consisting of optically thin plasma with temperatures ranging from 0.17keV to 60keV and a hot blackbody at ~90eV. The spect...

  1. SWIFT XRT Observations of the Nova-like Cataclysmic Variables MV Lyr, BZ Cam and V592 Cas

    CERN Document Server

    Balman, Solen; Sion, Edward M

    2014-01-01

    We present a total of ~ 45 ksec (3$\\times$15 ksec) of SWIFT XRT observations for three non-magnetic nova-like (NL) Cataclysmic Variables (CVs) (MV Lyr, BZ Cam, V592 Cas) in order to study characteristics of Boundary Layers (BL) in CVs. The nonmagnetic NLs are found mostly in a state of high mass accretion rate ($\\ge$1$\\times$10$^{-9}$ Msun yr$^{-1}$) and some show occasional low states. Using the XRT data, we find optically thin multiple-temperature cooling flow type emission spectra with X-ray temperatures (kT$_{max}$) of 21-50 keV. These hard X-ray emitting boundary layers diverge from simple isobaric cooling flows indicating X-ray temperatures that are of virial values in the disk. In addition, we detect power law emission components from MV Lyr and BZ Cam and plausibly from V592 Cas which may be a result of the Compton scattering of the optically thin emission from the fast wind outflows in these systems and/or Compton up-scattering of the soft disk photons. The X-ray luminosities of the (multi-temperatur...

  2. Accretion and Outflow in Interacting Binary Systems FUSE Observations of the Novalike Cataclysmic Variable, UX Ursae Majoris

    CERN Document Server

    Froning, C S; Knigge, C

    2003-01-01

    We present far-ultraviolet (905 -- 1182 A), time-series spectroscopy of the eclipsing, novalike cataclysmic variable, UX UMa, acquired with FUSE. The time-averaged spectrum is complex and is dominated by overlapping spectral features. The most prominent features are emission lines of CIII, NIII}, NIV, and OVI. They are broad (FWHM >= 1800 km/s) and double-peaked with a central absorption at zero velocity. During eclipse, the spectrum is simpler: the emission lines remain bright, but the absorption components of the lines and the weaker features between the emission lines disappear entirely, leaving a flat continuum. This behavior is also evident in GHRS (1149 -- 1660 A) spectra that we retrieved from the HST archive. The FUV spectra show flickering on time scales of several minutes. The flickering is seen primarily in the continuum and/or the weaker lines rather than in the prominent emission lines. The orbital light curve has a dip in the FUV flux between orbital phases 0.45 -- 0.65, similar to a pre-eclipse...

  3. Recovery of 29 s Oscillations in HST/FOS Eclipse Observations of the Cataclysmic Variable UX Ursae Majoris

    CERN Document Server

    Knigge, C; Long, K S; Wade, R A; Horne, K; Baptista, R

    1998-01-01

    [abridged abstract] Low amplitude (~=0.5%) 29-s oscillations have been detected in HST/FOS eclipse observations of the nova-like cataclysmic variable UX UMa. These are the same dwarf nova-type oscillations that were originally discovered in this system by Warner & Nather in 1972. The oscillations are sinusoidal to within the small observational errors and undergo an approximately -360 degree phase shift during eclipses. Their amplitudes are highest at pre-eclipse orbital phases and exhibit a rather gradual eclipse whose shape is roughly similar to UX~UMa's overall light curve. Oscillation spectra derived from pre-eclipse data segments are extremely blue, whereas mid-eclipse oscillation spectra are much redder. We suggest that the ultimate source of the oscillations is a hot, compact region near disk center, but that a significant fraction of the observed, modulated flux is due to reprocessing of the light emitted by this source in the accretion disk atmosphere. The compact source is occulted at orbital ph...

  4. Using Gaussian processes to model light curves in the presence of flickering: the eclipsing cataclysmic variable ASASSN-14ag

    CERN Document Server

    McAllister, M J; Dhillon, V S; Marsh, T R; Ashley, R P; Bours, M C P; Breedt, E; Hardy, L K; Hermes, J J; Kengkriangkrai, S; Kerry, P; Rattanasoon, S; Sahman, D I

    2016-01-01

    The majority of cataclysmic variable (CV) stars contain a stochastic noise component in their light curves, commonly referred to as flickering. This can significantly affect the morphology of CV eclipses and increases the difficulty in obtaining accurate system parameters with reliable errors through eclipse modelling. Here we introduce a new approach to eclipse modelling, which models CV flickering with the help of Gaussian processes (GPs). A parameterised eclipse model - with an additional GP component - is simultaneously fit to 8 eclipses of the dwarf nova ASASSN-14ag and system parameters determined. We obtain a mass ratio $q$ = 0.149 $\\pm$ 0.016 and inclination $i$ = 83.4 $^{+0.9}_{-0.6}$ $^{\\circ}$. The white dwarf and donor masses were found to be $M_{w}$ = 0.63 $\\pm$ 0.04 $M_{\\odot}$ and $M_{d}$ = 0.093 $^{+0.015}_{-0.012}$ $M_{\\odot}$, respectively. A white dwarf temperature $T_{w}$ = 14000 $^{+2200}_{-2000}$ K and distance $d$ = 146 $^{+24}_{-20}$ pc were determined through multicolour photometry. W...

  5. A Critical Examination of the Paradigm for the 2-3 Hour Period Gap in Cataclysmic Variables

    CERN Document Server

    Howell, S B; Rappaport, S; Howell, Steve B.; Nelson, Lorne A.

    2000-01-01

    We critically examine the basic paradigm for the origin of the 2-3 hr period gap in cataclysmic variables (CVs). We carry out an extensive population synthesis study of CVs starting from ~ 3 x 10^6 primordial binaries, and evolving some ~ 2 x 10^4 surviving systems through their CV phase. In particular we study current-epoch distributions of CVs in the $\\dot M-P_{orb}$, R_{2}-P_{orb}, M_{2}-P_{orb}, q-P_{orb}, T_{eff}-P_{orb}, and L_{2}-P_{orb} planes, where $\\dot M$ is the mass transfer rate, q is the mass ratio M_2/M_1, and M_2, R_2, T_{eff}, and L_2 are the donor star mass, radius, effective temperature, and luminosity, respectively. This work presents a new perspective on theoretical studies of the long-term evolution of CVs. In particular, we show that if the current paradigm is correct, the secondary masses in CVs just above the period gap should be as much as ~ 50% lower than would be inferred if one assumes a main-sequence radius-mass relation for the donor star.

  6. Barnes-Evans relations for dwarfs with an application to the determination of distances to cataclysmic variables

    CERN Document Server

    Beuermann, K

    2006-01-01

    Barnes-Evans type relations provide an empirical relationship between the surface brightness of stars and their color. They are widely used for measuring the distances to stars of known radii, as the Roche-lobe filling secondaries in cataclysmic variables (CVs). The calibration of the surface brightness of field dwarfs of near-solar metalicity with spectral types A0 to L8 covers all secondary spectral types detectable in CVs and related objects and will aid in the measurement of their distances. The calibrations are based on the radii of field dwarfs measured by the Infrared Flux Method and by interferometry. Published photometry is used and homogenized to the Cousins Rc and Ic and the CIT JHK photometric systems. The narrow band surface brightness at 7500A is based on our own and published spectrophotometry. Care is taken to select the dwarfs for near-solar metalicity, appropriate to CVs, and to avoid errors caused by unrecognized binarity. Relations are provided for the surface brightness in V, Rc, Ic, J, H...

  7. First Spitzer Space Telescope Observations of Magnetic Cataclysmic Variables: Evidence for Excess Emission at 3--8 microns

    CERN Document Server

    Howell, S B; Hoard, D W; Wachter, S; Harrison, T; Thomas, H C B; Stefaniak, L; Ciardi, D R; Szkody, P; Van Belle, G T; Howell, Steve B.; Brinkworth, Carolyn; Wachter, Stefanie; Harrison, Thomas; Thomas, Howard Chun Beth; Stefaniak, Linda; Ciardi, David R.; Szkody, Paula; Belle, Gerard van

    2006-01-01

    We present the first observations of magnetic cataclysmic variables with the Spitzer Space Telescope. We used the Infrared Array Camera to obtain photometry of the polars EF Eri, GG Leo, V347 Pav, and RX J0154.0-5947 at 3.6, 4.5, 5.8, and 8.0 $\\mu$m. In all of our targets, we detect excess mid-infrared emission over that expected from the component stars alone. We explore the origin of this IR excess by examining bremsstrahlung, cyclotron emission, circumbinary dust, and L/T brown dwarf secondary stars. Bremsstrahlung and cyclotron emission appear unlikely to be significant contributors to the observed fluxes. At present, the most likely candidate for the excess emission is dust that is probably located in a circumbinary disk with an inner temperature near 800 K. However, a simple dust disk plus any reasonable low mass or brown dwarf-like secondary star is unable to fully explain the observed flux densities in the 3--8 $\\mu$m region.

  8. Orbital periods of cataclysmic variables identified by the SDSS. IX. NTT photometry of eight eclipsing and three magnetic systems

    CERN Document Server

    Southworth, John; Gaensicke, B T; Copperwheat, C M

    2014-01-01

    We report the discovery of eclipses and the first orbital period measurements for four cataclysmic variables, plus the first orbital period measurements for one known eclipsing and two magnetic systems. SDSS J093537.46+161950.8 exhibits 1-mag deep eclipses with a period of 92.245 min. SDSS J105754.25+275947.5 has short and deep eclipses and an orbital period of 90.44 min. Its light curve has no trace of a bright spot and its spectrum is dominated by the white dwarf component, suggesting a low mass accretion rate and a very low-mass and cool secondary star. CSS J132536+210037 shows 1-mag deep eclipses each separated by 89.821 min. SDSS J075653.11+085831.8 shows 2-mag deep eclipses on a period of 197.154 min. CSS J112634-100210 is an eclipsing dwarf nova identified in the Catalina Real Time Transit Survey, for which we measure a period of 111.523 min. SDSS J092122.84+203857.1 is a magnetic system with an orbital period of 84.240 min; its light curve is a textbook example of cyclotron beaming. A period of 158.72...

  9. Optical Identification of Multiple Faint X-ray Sources in the Globular Cluster NGC 6752 Evidence for Numerous Cataclysmic Variables

    CERN Document Server

    Pooley, D; Homer, L; Verbunt, F; Anderson, S F; Gaensler, B M; Margon, B; Miller, J; Fox, D W; Kaspi, V M; Van der Klis, M

    2002-01-01

    We report on the Chandra ACIS-S3 imaging observation of the globular cluster NGC 6752. We detect 6 X-ray sources within the 10.5" core radius and 13 more within the 115" half-mass radius down to a limiting luminosity of Lx approx 10^{30} erg/s for cluster sources. We reanalyze archival data from the Hubble Space Telescope and the Australia Telescope Compact Array and make 12 optical identifications and one radio identification. Based on X-ray and optical properties of the identifications, we find 10 likely cataclysmic variables (CVs), 1-3 likely RS CVn or BY Dra systems, and 1 or 2 possible background objects. Of the 7 sources for which no optical identifications were made, we expect that ~2-4 are background objects and that the rest are either CVs or some or all of the 5 millisecond pulsars whose radio positions are not yet accurately known. These and other Chandra results on globular clusters indicate that the dozens of CVs per cluster expected by theoretical arguments are finally being found. The findings ...

  10. Global MHD Simulations of Accretion Disks in Cataclysmic Variables (CVs). II. The Relative Importance of MRI and Spiral Shocks

    Science.gov (United States)

    Ju, Wenhua; Stone, James M.; Zhu, Zhaohuan

    2017-05-01

    We perform global three-dimensional MHD simulations of unstratified accretion disks in cataclysmic variables (CVs). By including mass inflow via an accretion stream, we are able to evolve the disk to a steady state. We investigate the relative importance of spiral shocks and the magnetorotational instability (MRI) in driving angular momentum transport and how each depend on the geometry and strength of the seed magnetic field and the Mach number of the disk (where Mach number is the ratio of the azimuthal velocity and the sound speed of gas). We use a locally isothermal equation of state and adopt temperature profiles that are consistent with CV disk observations. Our results indicate that the relative importance of spiral shocks and MRI in driving angular momentum transport is controlled by the gas Mach number and the seed magnetic field strength. MRI and spiral shocks provide comparable efficiency of angular momentum transport when the disk Mach number is around 10 and the seed magnetic field has plasma β =400 (where β is the ratio of gas pressure and magnetic pressure). The MRI dominates whenever the seed field strength, or the disk Mach number, is increased. Among all of our simulations, the effective viscosity parameter {α }{eff}˜ 0.016{--}0.1 after MRI saturates and the disk reaches steady state. Larger values of {α }{eff} are favored when the seed magnetic field has vertical components or the flow has stronger magnetization (1/β ). Our models all indicate that the role of MRI in driving angular momentum transport thus mass accretion in CV disks is indispensable, especially in cool disks with weak spiral shocks.

  11. UNAMBIGUOUS DETECTION OF REFLECTION IN MAGNETIC CATACLYSMIC VARIABLES: JOINT NuSTAR–XMM-NEWTON OBSERVATIONS OF THREE INTERMEDIATE POLARS

    Energy Technology Data Exchange (ETDEWEB)

    Mukai, K. [CRESST and X-ray Astrophysics Laboratory, NASA/GSFC, Greenbelt, MD 20771 (United States); Rana, V. [Cahill Center for Astronomy and Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Bernardini, F. [New York University Abu Dhabi, P.O. Box 129188, Abu Dhabi (United Arab Emirates); De Martino, D., E-mail: Koji.Mukai@nasa.gov [INAF—Osservatorio Astronomico di Capodimonte, Salita Moiariello 16, I-80131 Napoli (Italy)

    2015-07-10

    In magnetic cataclysmic variables (CVs), X-ray emission regions are located close to the white dwarf surface, which is expected to reflect a significant fraction of intrinsic X-rays above 10 keV, producing a Compton reflection hump. However, up to now, a secure detection of this effect in magnetic CVs has largely proved elusive because of the limited sensitivity of non-imaging X-ray detectors. Here we report our analysis of joint NuSTAR–XMM-Newton observations of three magnetic CVs, V709 Cas, NY Lup, and V1223 Sgr. The improved hard X-ray sensitivity of the imaging NuSTAR data has resulted in the first robust detection of Compton hump in all three objects, with amplitudes of ∼1 or greater in NY Lup, and likely <1.0 in the other two. We also confirm earlier reports of a strong spin modulation above 10 keV in V709 Cas, and we report the first detection of small spin amplitudes in the others. We interpret this as due to different height of the X-ray emitting region among these objects. A height of ∼0.2 white dwarf radii provides a plausible explanation for the low reflection amplitude of V709 Cas. Since emission regions above both poles are visible at certain spin phases, this can also explain the strong hard X-ray spin modulation. A shock height of ∼0.05 white dwarf radii can explain our results on V1223 Sgr, while the shock height in NY Lup appears negligible.

  12. Galactic model parameters of cataclysmic variables: Results from a new absolute magnitude calibration with 2MASS and WISE

    Science.gov (United States)

    Özdönmez, A.; Ak, T.; Bilir, S.

    2015-01-01

    In order to determine the spatial distribution, Galactic model parameters and luminosity function of cataclysmic variables (CVs), a J-band magnitude limited sample of 263 CVs has been established using a newly constructed period-luminosity-colours (PLCs) relation which includes J,Ks and W1-band magnitudes in 2MASS and WISE photometries, and the orbital periods of the systems. This CV sample is assumed to be homogeneous regarding to distances as the new PLCs relation is calibrated with new or re-measured trigonometric parallaxes. Our analysis shows that the scaleheight of CVs is increasing towards shorter periods, although selection effects for the periods shorter than 2.25 h dramatically decrease the scaleheight: the scaleheight of the systems increases from 192 pc to 326 pc as the orbital period decreases from 12 to 2.25 h. The z-distribution of all CVs in the sample is well fitted by an exponential function with a scaleheight of 213-10+11 pc. However, we suggest that the scaleheight of CVs in the Solar vicinity should be ∼300 pc and that the scaleheights derived using the sech2 function should be also considered in the population synthesis models. The space density of CVs in the Solar vicinity is found 5.58(1.35)×10-6 pc-3 which is in the range of previously derived space densities and not in agreement with the predictions of the population models. The analysis based on the comparisons of the luminosity function of white dwarfs with the luminosity function of CVs in this study show that the best fits are obtained by dividing the luminosity functions of white dwarfs by a factor of 350-450.

  13. The implications of disc instabilities on cataclysmic Variable structure and evolution

    Directory of Open Access Journals (Sweden)

    J. P. Lasota

    2004-01-01

    Full Text Available Al aplicar el modelo de inestabilidad t ermico-viscosa del disco a varias clases de variables catacl smicas, con frecuencia se requiere que el disco de acreci on sea truncado. Arguyo que en la mayor a de los casos este truncamiento interno se debe al campo magn etico de la enana blanca.

  14. FUSE Observations of the Bright, Eclipsing Nova-like Cataclysmic Variable, UX UMa (FUSE 2000)

    Science.gov (United States)

    Long, Knox; Froning, Cynthia

    2004-01-01

    This was a project to study the disk and wind of the eclipsing nova-like variable UX UMa, in order to better define the wind geometry of the system, including the nature of the transition region between the disk photosphere and the supersonic wind. We proposed to use phase resolved spectroscopy of the system, taking advantage of the fact that UX UMa is an eclipsing system, to isolate different regions of the wind and to use a Monte Carlo radiative transfer code to simulate the spectra through the eclipse.

  15. Some updates on the role of magnetic fields in Cataclysmic variables

    Directory of Open Access Journals (Sweden)

    Coel Hellier

    2004-01-01

    Full Text Available En este resumen se cubren algunos aspectos de los recientes desarrollos en la comprensi on del papel que juegan los campos magn eticos en variables catacl smicas: presento una discusi on sobre los recientes modelos de uni caci on DNO{QPO; los l mites de la magnetosfera del disco; algunas cuestiones relacionadas con la componente suave de cuerpo negro y la naturaleza de los espectros de rayos X en MCVs; si las estellas SW Sex son magn eticas; y nalmente, menciono el raro comportamiento de FS Aur y HS 2331+3905.

  16. Observational studies of cataclysmic variable evolution: Of samples, biases and surprises

    Directory of Open Access Journals (Sweden)

    B.T. Gansicke

    2004-01-01

    Full Text Available Presento un breve informe sobre el estado de tres grandes proyectos observacionales destinados a veri car nuestra actual comprensi on de la evoluci on de variables catacl smicas (CVs: la selecci on espectrosc opica de las nuevas CVs en el Hamburg Quasar Survey, la b usqueda de pre-CVs bas andose en los colores de Sloan y en la espectroscop a multi-objeto UK Schmidt/6dF y la identi caci on de CVs que proceden de binarias de rayos X supersuaves, utilizando el \\survey" espectrosc opico en el ultravioleta lejano del HST/STIS.

  17. Observational studies of cataclysmic variable evolution: Of samples, biases and surprises

    OpenAIRE

    Gansicke, B. T.

    2004-01-01

    Presento un breve informe sobre el estado de tres grandes proyectos observacionales destinados a veri car nuestra actual comprensi on de la evoluci on de variables catacl smicas (CVs): la selecci on espectrosc opica de las nuevas CVs en el Hamburg Quasar Survey, la b usqueda de pre-CVs bas andose en los colores de Sloan y en la espectroscop a multi-objeto UK Schmidt/6dF y la identi caci on de CVs que proceden de binarias de rayos X supersuaves, utilizando el \\survey" espectrosc ...

  18. Doppler Tomography of Cataclysmic Variables with a 6.5-m class Telescope

    Directory of Open Access Journals (Sweden)

    J. Echevarría

    2007-01-01

    Full Text Available Se est llevando a cabo un proyecto a largo plazo de espectroscop a de alta dispersi n (R 20000 para observar y analizar una muestra de variables catacl smicas con el telescopio de 2.1-m en el Observatorio Astron mico Nacional en San Pedro M rtir y el espectr grafo echelle. La herramienta principal para este an lisis es la tomograf a Doppler. En esta contribuci n presentamos nuestro trabajo y abordamos la pregunta: >C mo podr amos mejorar este proyecto con un telescopio de clase 6.5-m?

  19. Modeling the diverse fuv spectra of disk-dominated Cataclysmic variables

    Directory of Open Access Journals (Sweden)

    Knox S. Long

    2004-01-01

    Full Text Available Los espectros de FUSE y HST de novas enanas en explosiones y de variables semejantes a novas presentan un amplio rango de caracter sticas. En unos cuantos sistemas existen se~nales obvias de un viento r apido en la forma de los per les de OVI semejantes a P-Cygni y de otros iones en relativamente altos estados de ionizaci on. Pero estos casos son raros. Son m as comunes los sistemas con espectros FUV que presentan una compleja mezcla de l neas de alto y bajo estado de ionizaci on. Se describen intentos para reproducir los espectros utilizando el c odigo de Monte Carlo de transferencia radiativa, desarrollado para modelar vientos bic onicos en sistemas de disco.

  20. The X-ray properties of the magnetic Cataclysmic Variable UU Col

    CERN Document Server

    De Martino, D; Mukai, K; Bonnet-Bidaud, J M; Burwitz, V; Gänsicke, B T; Haberl, F; Mouchet, M

    2006-01-01

    XMM-Newton observations aimed at determining for the first time the broad-band X-ray properties of the faint high galactic latitude Intermediate Polar UU Col are presented. We performed X-ray timing analysis in different energy ranges of the EPIC cameras which reveals the dominance of the 863s white dwarf rotational period. The spin pulse is strongly energy dependent. Weak variabilities at the beat 935s and at the 3.5hr orbital periods are also observed, but the orbital modulation is detected only below 0.5keV. Simultaneous UV and optical photometry shows that the spin pulse is anti-phased with respect to the hard X-rays. Analysis of the EPIC and RGS spectra reveals the complexity of the X-ray emission, being composed of a soft 50eV black--body component and two optically thin emission components at 0.2keV and 11keV strongly absorbed by dense material with an equivalent hydrogen column density of 10**(23)cm**(-2) partially (50%) covering the X-ray source. The complex X-ray and UV/optical temporal behaviour in...

  1. Wavelets with Ridges: A High-Resolution Representation of Cataclysmic Variable Time-Series

    CERN Document Server

    Blackman, Claire

    2010-01-01

    Quasi-periodic oscillations and dwarf nova oscillations occur in dwarf novae and nova-like variables during outburst and occasionally during quiescence, and have analogues in high-mass X-ray binaries and black-hole candidates. The frequent low coherence of quasi-period oscillations and dwarf nova oscillations can make detection with standard time-series tools such as periodograms problematic. This paper develops tools to analyse quasi-periodic brightness oscillations. We review the use of time-frequency representations in the astronomical literature, and show that representations such as the Choi-Williams Distribution and Zhao-Atlas-Marks Representation, which are best suited to high signal-to-noise data, cannot be assumed a priori to be the best techniques for our data, which have a much higher noise level and lower coherence. This leads us to a detailed analysis of the time-frequency resolution and statistical properties of six time-frequency representations. We conclude that the wavelet scalogram, with the...

  2. Recovery of 29 Second Oscillations in Hubble Space Telescope Eclipse Observations of the Cataclysmic Variable UX Ursae Majoris

    Science.gov (United States)

    Knigge, Christian; Drake, Nick; Long, Knox S.; Wade, Richard A.; Horne, Keith; Baptista, Raymundo

    1998-01-01

    Low-amplitude (approximately 0.5%) 29 s oscillations have been detected in Hubble Space Telescope Faint Object Spectrograph eclipse observations of the nova-like cataclysmic variable UX UMa. These are the same dwarf nova-type oscillations that were originally discovered in this system in 1972. The 29 s oscillations are seen in one pair of eclipse sequences obtained with the FOS/PRISM in 1994 November but not in a similar pair obtained with the FOS/GI60L grating in August of the same year. The oscillations in the PRISM data are sinusoidal to within the small observational errors and undergo an approximately - 360' phase shift during eclipses (i.e., one cycle is lost). The amplitudes are highest at pre-eclipse orbital phases and exhibit a rather gradual eclipse whose shape is roughly similar to, although perhaps slightly narrower than, LTX UMa's overall light curve in the PRISM bandpass (2000-8000 A). Spectra of the oscillations have been constructed from pre-, mid, and post-eclipse data segments of the November observations. The spectra obtained from the out-of-eclipse segments are extremely blue, and only lower limits can be placed on the temperature of the source that dominates the modulated flux at these orbital phases. Lower limits derived from blackbody (stellar atmosphere) model fits to these data are >or equal to 95,000 K (> or equal to 85,000 K); the corresponding upper limits on the projected area of this source are all less than 2% of the white dwarf (WD) surface area. By contrast, oscillation spectra derived from mid- eclipse data segments are much redder. Fits to these spectra yield temperature estimates in the range 20,000 K approximately greater T and T approximately less than 30,000 K for both blackbody and stellar atmosphere models and corresponding projected areas of a few percent of the WD surface area. These estimates are subject to revision if the modulated emission is optically thin. We suggest that the ultimate source of the oscillations is a

  3. X-ray emission line spectroscopy of cataclysmic variables. II. Temperatures and densities from line ratios in the Chandra HETG band

    Energy Technology Data Exchange (ETDEWEB)

    Schlegel, E. M.; Shipley, H. V. [Department of Physics and Astronomy, University of Texas-San Antonio, San Antonio, TX 78249 (United States); Rana, V. R. [Space Radiation Laboratory, Caltech, Pasadena, CA 91125 (United States); Barrett, P. E. [US Naval Observatory, Washington, DC 20392-5420 (United States); Singh, K. P., E-mail: eric.schlegel@utsa.edu, E-mail: vrana@srl.caltech.edu, E-mail: barrett.paul@usno.navy.mil, E-mail: singh@tifr.res.in [Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai (India)

    2014-12-10

    We summarize the results of a line-by-line fitting analysis of the available spectra obtained using the Chandra High-Energy Transmission Grating. We confirm the existence of broad ionization and electron temperature ranges and high number densities in cataclysmic variables (CVs) of all subtypes. Temperatures range from ∼0.4 keV to ∼5-10 keV or more with a broad range detected in any given CV. In other words, single-temperature models do not describe the line emission. Number densities also cover a broad range, from 10{sup 12} to >10{sup 16} cm{sup –3}. We demonstrate that much of the plasma is in a nonequilibrium state; the Fe emission, however, may arise from plasma in the ionization equilibrium.

  4. Variability of the Spin Period of the White Dwarf in the Magnetic Cataclysmic Binary System EX Hya

    CERN Document Server

    Andronov, Ivan L

    2013-01-01

    The observations of the two-periodic magnetic cataclysmic system EX Hya have been carried out, using the telescopes RC16 and TOA-150 of the Tzec Maun observatory. 6 nights of observations were obtained in 2010-2011 (alternatively changing filters VR). Also the databases of WASP, ASAS and AAVSO have been analyzed. Processing time series was carried out using the program MCV. We analyzed changes in the rotation period of the white dwarf, and based on our own and previously published moments of maximum. The ephemeris was determined for the maxima of the radiation flux associated with the rotation of the magnetic white dwarf: Tmax=2437699.89079(59) +0.0465464808(69).E-6.3(2)*10^{-13}E^2, which corresponds to the characteristic timescale of the rotation spin-up of 4.67(14)*10^6 years. This contradicts the estimated value of the mass of the white dwarf of 0.42M_\\odot, based on X-ray observations made by Yuasa et al (2010), however, is consistent with estimates of the masses of 0.79 M_\\odot (white dwarf) and 0.108 M...

  5. HS0139+0559, HS0229+8016, HS0506+7725 and HS0642+5049: Four new long-period cataclysmic variables

    CERN Document Server

    Aungwerojwit, A; Rodríguez-Gil, P; Hagen, H J; Harlaftis, E T; Papadimitriou, C; Lehto, H; Araújo-Betancor, S; Heber, U; Fried, R E; Engels, D; Katajainen, S

    2005-01-01

    We present time-resolved optical spectroscopy and photometry of four relatively bright (V~14.0-15.5) long-period cataclysmic variables (CVs) discovered in the Hamburg Quasar Survey: HS0139+0559, HS0229+8016, HS0506+7725 and HS0642+5049. Their respective orbital periods, 243.69+-0.49min, 232.550+-0.049min, 212.7+-0.2min and 225.90+-0.23min are determined from radial velocity and photometric variability studies. HS0506+7725 is characterised by strong Balmer and He emission lines, short-period (~10-20min) flickering and weak X-ray emission in the ROSAT All Sky Survey. The detection of a deep low state (~18.5) identifies HS0506+7725 as a member of the VY Scl stars. HS0139+0559, HS0229+8016 and HS0642+5049 display thick-disc like spectra and no or only weak flickering activity. HS0139+0559 and HS0229+8016 exhibit clean quasi-sinusoidal radial velocity varations of their emission lines but no or very little orbital photometric variability. In contrast, we detect no radial velocity variation in HS0642+5049 but a not...

  6. Time resolved spectroscopy and photometry of three little known bright cataclysmic variables: LS IV -08$^{\\rm o}$ 3, HQ Monocerotis and ST Chamaeleontis

    CERN Document Server

    Bruch, Albert

    2016-01-01

    As part of a project to better characterize comparatively bright but so far little studied cataclysmic variables in the southern hemisphere, we have obtained spectroscopic and photometric data of the nova-like variables LS IV -08$^{\\rm o}$ 3 and HQ Mon, and of the Z Cam type dwarf nova ST Cha. The spectra of all systems are as expected for their respective types. We derive improved orbital ephemeris of LS IV -08$^{\\rm o}$ 3 and map its accretion disk in the light of the H$\\alpha$ emission using Doppler tomography. We find that the emission has a two component origin, arising in the outer parts of the accretion disk and possibly on the illuminated face of the secondary star. The light curve of LS IV -08$^{\\rm o}$ 3 exhibits a low level of flickering and indications for a modulation on the orbital period. Spectroscopy of HQ Mon suggests an orbital period of $\\approx$5.15 hours which is incompatible with previous (uncertain) estimates. The light curves show the typical low scale flickering of UX UMa type nova-li...

  7. Periodic signals from the Circinus region: two new cataclysmic variables and the ultraluminous X-ray source candidate GC X-1

    CERN Document Server

    Esposito, P; Milisavljevic, D; Mapelli, M; Zampieri, L; Sidoli, L; Fabbiano, G; Castillo, G A Rodríguez

    2015-01-01

    The examination of two 2010 Chandra ACIS exposures of the Circinus galaxy resulted in the discovery of two pulsators: CXO J141430.1-651621 and CXOU J141332.9-651756. We also detected 26-ks pulsations in CG X-1, consistently with previous measures. For ~40 other sources, we obtained limits on periodic modulations. In CXO J141430.1-651621, which is ~2 arcmin outside the Circinus galaxy, we detected signals at 6120(1) s and 64.2(5) ks. In the longest observation, the source showed a flux of ~1.1e-13 erg/cm^2/s (absorbed, 0.5-10 keV) and the spectrum could be described by a power-law with photon index ~1.4. From archival observations, we found that the luminosity is variable by ~50 per cent on time-scales of weeks-years. The two periodicities pin down CXO J141430.1-651621 as a cataclysmic variable of the intermediate polar subtype. The period of CXOU J141332.9-651756 is 6378(3) s. It is located inside the Circinus galaxy, but the low absorption indicates a Galactic foreground object. The flux was ~5e-14 erg/cm^2/...

  8. MOCCA-SURVEY database I. Accreting white dwarf binary systems in globular clusters -- II. Cataclysmic variables -- progenitors and population at birth

    CERN Document Server

    Belloni, Diogo; Rocha-Pinto, Helio J; Leigh, Nathan; Askar, Abbas

    2016-01-01

    This is the second in a series of papers associated with cataclysmic variables (CVs) and related objects, formed in a suite of simulations for globular cluster evolution performed with the MOCCA Monte Carlo code. We study the properties of our simulated CV populations throughout the entire cluster evolution. We find that dynamics extends the range of binary CV progenitor properties, causing CV formation from binary progenitors that would otherwise not become CVs. The CV formation rate in our simulations can be separated into two regimes: an initial burst ($\\lesssim$ 1 Gyr) connected with the formation of the most massive WDs, followed by a nearly constant formation rate. This result holds for all models regardless of the adopted initial conditions, even when most CVs form dynamically. Given the cluster age-dependence of CV properties, we argue that direct comparisons to observed Galactic field CVs could be misleading, since cluster CVs can be up to 4 times older than their field counterparts. Our results also...

  9. Identification of Faint Chandra X-ray Sources in the Core-Collapsed Globular Cluster NGC 6397: Evidence for a Bimodal Cataclysmic Variable Population

    CERN Document Server

    Cohn, Haldan N; Couch, Sean M; Anderson, Jay; Cool, Adrienne M; Berg, Maureen van den; Bogdanov, Slavko; Heinke, Craig O; Grindlay, Jonathan E; 10.1088/0004-637X/722/1/20

    2011-01-01

    We have searched for optical identifications for 79 Chandra X-ray sources that lie within the half-mass radius of the nearby, core-collapsed globular cluster NGC 6397, using deep Hubble Space Telescope Advanced Camera for Surveys Wide Field Channel imaging in H-alpha, R, and B. Photometry of these images allows us to classify candidate counterparts based on color-magnitude diagram location. In addition to recovering nine previously detected cataclysmic variables (CVs), we have identified six additional faint CV candidates, a total of 42 active binaries (ABs), two millisecond pulsars (MSPs), one candidate active galactic nucleus, and one candidate interacting galaxy pair. Of the 79 sources, 69 have a plausible optical counterpart. The 15 likely and possible CVs in NGC 6397 mostly fall into two groups: a brighter group of six for which the optical emission is dominated by contributions from the secondary and accretion disk, and a fainter group of seven for which the white dwarf dominates the optical emission. T...

  10. MOCCA-SURVEY database I. Accreting white dwarf binary systems in globular clusters - II. Cataclysmic variables - progenitors and population at birth

    Science.gov (United States)

    Belloni, Diogo; Giersz, Mirek; Rocha-Pinto, Helio J.; Leigh, Nathan W. C.; Askar, Abbas

    2016-10-01

    This is the second in a series of papers associated with cataclysmic variables (CVs) and related objects, formed in a suite of simulations for globular cluster evolution performed with the MOCCA Monte Carlo code. We study the properties of our simulated CV populations throughout the entire cluster evolution. We find that dynamics extends the range of binary CV progenitor properties, causing CV formation from binary progenitors that would otherwise not become CVs. The CV formation rate in our simulations can be separated into two regimes: an initial burst (≲ 1 Gyr) connected with the formation of the most massive WDs, followed by a nearly constant formation rate. This result holds for all models regardless of the adopted initial conditions, even when most CVs form dynamically. Given the cluster age-dependence of CV properties, we argue that direct comparisons to observed Galactic field CVs could be misleading, since cluster CVs can be up to 4 times older than their field counterparts. Our results also illustrate that, due mainly to unstable mass transfer, some CVs that form in our simulations are destroyed before the present-day. Finally, some field CVs might have originated from GCs, as found in our simulations, although the fraction of such escapers should be small relative to the entire Galactic field CV population.

  11. MOCCA-SURVEY database I. Accreting white dwarf binary systems in globular clusters - II. Cataclysmic variables - progenitors and population at birth

    Science.gov (United States)

    Belloni, Diogo; Giersz, Mirek; Rocha-Pinto, Helio J.; Leigh, Nathan W. C.; Askar, Abbas

    2017-02-01

    This is the second in a series of papers associated with cataclysmic variables (CVs) and related objects, formed in a suite of simulations for globular cluster evolution performed with the MOCCA Monte Carlo code. We study the properties of our simulated CV populations throughout the entire cluster evolution. We find that dynamics extends the range of binary CV progenitor properties, causing CV formation from binary progenitors that would otherwise not become CVs. The CV formation rate in our simulations can be separated into two regimes: an initial burst (≲1 Gyr) connected with the formation of the most massive white dwarfs, followed by a nearly constant formation rate. This result holds for all models regardless of the adopted initial conditions, even when most CVs form dynamically. Given the cluster age-dependence of CV properties, we argue that direct comparisons to observed Galactic field CVs could be misleading, since cluster CVs can be up to four times older than their field counterparts. Our results also illustrate that, due mainly to unstable mass transfer, some CVs that form in our simulations are destroyed before the present day. Finally, some field CVs might have originated from globular clusters, as found in our simulations, although the fraction of such escapers should be small relative to the entire Galactic field CV population.

  12. Dynamical mass transfer in cataclysmic binaries

    Science.gov (United States)

    Melia, Fulvio; Lamb, D. Q.

    1987-01-01

    When a binary comes into contact and mass transfer begins, orbital angular momentum is stored in the accretion disk until the disk couples tidally to the binary system. Taam and McDermott (1987) have suggested that this leads to unstable dynamical mass transfer in many cataclysmic variables in which mass transfer would otherwise be stable, and that it explains the gap between 2 and 3 h in the orbital period distribution of these systems. Here the consequences of this hypothesis for the evolution of cataclysmic binaries are explored. It is found that systems coming into contact longward of the period gap undergo one or more episodes of dynamical mass transfer.

  13. Time resolved spectroscopy and photometry of three little known bright cataclysmic variables: LS IV -08° 3, HQ Monocerotis and ST Chamaeleontis

    Science.gov (United States)

    Bruch, Albert; Diaz, Marcos P.

    2017-01-01

    As part of a project to better characterize comparatively bright but so far little studied cataclysmic variables in the southern hemisphere, we have obtained spectroscopic and photometric data of the nova-like variables LS IV -08° 3 and HQ Mon, and of the Z Cam type dwarf nova ST Cha. The spectra of all systems are as expected for their respective types. We derive improved orbital ephemeris of LS IV -08° 3 and map its accretion disk in the light of the Hα emission using Doppler tomography. We find that the emission has a two component origin, arising in the outer parts of the accretion disk and possibly on the illuminated face of the secondary star. The light curve of LS IV -08° 3 exhibits a low level of flickering and indications for a modulation on the orbital period. Spectroscopy of HQ Mon suggests an orbital period of ≈ 5h.15 which is incompatible with previous (uncertain) estimates. The light curves show the typical low scale flickering of UX UMa type nova-like systems, superposed upon variations on longer time scales. During one night a modulation with a period of ≈ 41m is observed, visible for at least 4 hours. However, it does not repeat itself in other nights. A spectroscopic orbital period of ≈ 5h.5 is derived for ST Cha. A previously suspected period of 6h.8 (or alternatively 9h.6), based on historical photographic photometry is incompatible with the spectroscopic period. Moreover, we show that our new as well as previous photometry does not contain evidence for the quoted photometric period.

  14. Very-high-energy gamma-ray observations of pulsar wind nebulae and cataclysmic variable stars with MAGIC and development of trigger systems for IACTs

    Science.gov (United States)

    Lopez-Coto, Ruben

    2015-07-01

    lowest possible energy threshold with the LSTs of CTA. Together with this work, the trigger of the MAGIC telescopes was improved. We have simulated, tested and commissioned a new concept of stereoscopic trigger. This new system, that uses the information of the position of the showers on each of the MAGIC cameras, is dubbed "Topo-trigger". The scientific fraction of the thesis deals with galactic sources observed with the MAGIC telescopes. In Part III, I talk about the analysis of the VHE γ-ray emission of Pulsar Wind Nebulae (PWNe): the discovery of VHE γ-ray emission from the puzzling PWN 3C 58, the likely remnant of the SN 1181 AD and the weakest PWN detected at VHE to date; the characterization of the VHE tail of the Crab nebula by observing it at the highest zenith angles; and the search for an additional inverse Compton component during the Crab nebula flares reported by Fermi-LAT in the synchrotron regime. Part IV is concerned with searches for VHE γ-ray emission of cataclysmic variable stars. I studied, on a multiwavelength context, the VHE γ-ray nature of the previously claimed pulsed γ-ray emission of the cataclysmic variable AE Aqr. I also performed observations of novae and a dwarf nova to pinpoint the ac- celeration mechanisms taking place in this kind of objects and to discover a putative hadronic component of the soft γ-ray emission. A conclusion chapter summarizes all the work performed and lists prospects related with the topics treated in this thesis.

  15. Data Mining of Cataclysmic Variables Candidates in Massive Spectra%海量光谱中激变变星候选体的数据挖掘

    Institute of Scientific and Technical Information of China (English)

    姜斌; 罗阿理; 赵永恒

    2011-01-01

    提出一套适用于海量光谱自动快速筛选激变变星的方法.利用已证认的激变变星光谱作为模板,使用主分量分析提取主特征后构造光谱特征矩阵,将海量光谱利用光谱特征矩阵映射到特征空间后,使用支持向量机排除大部分非候选体,最后对较少数量的候选体进行模板匹配并证认,结果作为反馈进一步丰富模板库.实验发现了58个新的激变变星候选体,表明了该方法的可行性,为在LAMOST海量光谱中快速搜索激变变星等稀少天体提供了有效途径.%An automatic and efficient method for LAMOST's massive spectral data reduction is presented in this paper. The identified cataclysmic variables were selected as templates to construct the feature space by PCA(the principal component analysis), and most of the non-candidates were excluded by the method using support vector machine. Template matching strategy was used to identify the final candidates which were analyzed to complement the templates as feedback. Fifty eight new CVs candidates were found in the experiment, showing that our approach to finding special celestial bodies can be practical in LAM-OST.

  16. SDSS J105754.25+275947.5: a period-bounce eclipsing cataclysmic variable with the lowest-mass donor yet measured

    Science.gov (United States)

    McAllister, M. J.; Littlefair, S. P.; Dhillon, V. S.; Marsh, T. R.; Gänsicke, B. T.; Bochinski, J.; Bours, M. C. P.; Breedt, E.; Hardy, L. K.; Hermes, J. J.; Kengkriangkrai, S.; Kerry, P.; Parsons, S. G.; Rattanasoon, S.

    2017-05-01

    We present high-speed, multicolour photometry of the faint, eclipsing cataclysmic variable (CV) SDSS J105754.25+275947.5. The light from this system is dominated by the white dwarf. Nonetheless, averaging many eclipses reveals additional features from the eclipse of the bright spot. This enables the fitting of a parametrized eclipse model to these average light curves, allowing the precise measurement of system parameters. We find a mass ratio of q = 0.0546 ± 0.0020 and inclination i = 85.74 ± 0.21°. The white dwarf and donor masses were found to be Mw = 0.800 ± 0.015 M⊙ and Md = 0.0436 ± 0.0020 M⊙, respectively. A temperature Tw = 13300 ± 1100 K and distance d = 367 ± 26 pc of the white dwarf were estimated through fitting model atmosphere predictions to multicolour fluxes. The mass of the white dwarf in SDSS 105754.25+275947.5 is close to the average for CV white dwarfs, while the donor has the lowest mass yet measured in an eclipsing CV. A low-mass donor and an orbital period (90.44 min) significantly longer than the period minimum strongly suggest that this is a bona fide period-bounce system, although formation from a white dwarf/brown dwarf binary cannot be ruled out. Very few period-minimum/period-bounce systems with precise system parameters are currently known, and as a consequence the evolution of CVs in this regime is not yet fully understood.

  17. The accretion disk in the post period-minimum cataclysmic variable SDSS J080434.20+510349.2

    CERN Document Server

    Zharikov, S; Aviles, A; Michel, R; Gonzalez-Buitrago, D; Garcia-Diaz, Ma T

    2012-01-01

    This study of SDSS0804 is primarily concerned with the double-hump shape in the light curve and its connection with the accretion disk in this bounce-back system. Time-resolved photometric and spectroscopic observations were obtained to analyze the behavior of the system between superoutbursts. A geometric model of a binary system containing a disk with two outer annuli spiral density waves was applied to explain the light curve and the Doppler tomography. Observations were carried out during 2008-2009, after the object's magnitude decreased to V~17.7(0.1) from the March 2006 eruption. The light curve clearly shows a sinusoid-like variability with a 0.07 mag amplitude and a 42.48 min periodicity, which is half of the orbital period of the system. In Sept. 2010, the system underwent yet another superoutburst and returned to its quiescent level by the beginning of 2012. This light curve once again showed a double-humps, but with a significantly smaller ~0.01mag amplitude. Other types of variability like a "mini...

  18. Spectroscopy from the Hubble Space Telescope Cosmic Origins Spectrograph of the Southern Nova-like BB Doradus in an Intermediate State

    Science.gov (United States)

    Godon, Patrick; Sion, Edward M.; Gänsicke, Boris T.; Hubeny, Ivan; de Martino, Domitilla; Pala, Anna F.; Rodríguez-Gil, Pablo; Szkody, Paula; Toloza, Odette

    2016-12-01

    We present a spectral analysis of the spectrum from the Hubble Space Telescope Cosmic Origins Spectrograph (HST/COS) of the southern VY Scl nova-like variable BB Doradus, obtained as part of a Cycle 20 HST/COS survey of accreting white dwarfs (WDs) in cataclysmic variables. BB Dor was observed with COS during an intermediate state with a low mass accretion rate, thereby allowing an estimate of the WD temperature. The results of our spectral analysis show that the WD is a significant far-ultraviolet (FUV) component of the spectrum with a temperature of about 35,000-50,000 K, assuming a WD mass of 0.80 {M}⊙ ({log}(g)=8.4). The disk, with a mass accretion rate of ≈ {10}-10 {M}⊙ {{yr}}-1, contributes about 1/5 to 1/2 of the FUV flux.

  19. Terminal Cataclysm Epistemology: A Cataclysm that Never Happened?

    Science.gov (United States)

    Hartmann, W. K.

    2015-07-01

    The "terminal cataclysm" or "late heavy bombardment," concept of the last 40 years exhibits curious epistemology, with changing definitions and inconsistent evidence. A sharp "spike" in solar system basin formation at 3.9 Ga ago is untenable.

  20. The fight for accretion: discovery of intermittent mass transfer in BB Doradus in the low state

    CERN Document Server

    Rodríguez-Gil, P; Long, K S; Gänsicke, B T; Torres, M A P; Rubio-Díez, M M; Santander-García, M

    2012-01-01

    Our long-term photometric monitoring of southern nova-like cataclysmic variables with the 1.3-m SMARTS telescope found BB Doradus fading from V ~ 14.3 towards a deep low state at V ~ 19.3 in April 2008. Here we present time-resolved optical spectroscopy of BB Dor in this faint state in 2009. The optical spectrum in quiescence is a composite of a hot white dwarf with Teff = 30000 +- 5000 K and a M3-4 secondary star with narrow emission lines (mainly of the Balmer series and HeI) superposed. We associate these narrow profiles with an origin on the donor star. Analysis of the radial velocity curve of the H-alpha emission from the donor star allowed the measurement of an orbital period of 0.154095 +- 0.000003 d (3.69828 +- 0.00007 h), different from all previous estimates. We detected episodic accretion events which veiled the spectra of both stars and radically changed the line profiles within a timescale of tens of minutes. This shows that accretion is not completely quenched in the low state. During these accr...

  1. Data Mining Approach to Cataclysmic Variables Candidates Based on Random Forest Algorithm%基于随机森林的激变变星候选体的数据挖掘

    Institute of Scientific and Technical Information of China (English)

    姜斌; 罗阿理; 赵永恒

    2012-01-01

    提出一种适用于在郭守敬望远镜海量光谱中自动、快速筛选激变变星的方法.利用已证认的激变变星光谱作为模板,通过随机森林分类训练,得到一个分类模型,该模型给出了各个波长对应流量的重要性排序,可根据该排序进行降维并用于激变变星判别,结果作为反馈进一步丰富模板库.实验中共发现了16个新的激变变星候选体,表明了该方法的可行性.%An automatic and efficient method for cataclysmic variables candidates is presented in the present paper. The identified CVs were selected as templates. A model was constructed by random forest algorithm with templates and random selected spectra. Wavelength ranking was described by the model and the classifier was constructed afterwards. Most of the non-candidates were excluded by the method. Template matching strategy was used to identify the final candidates which were analyzed to complement the templates as feedback. 16 new CVs candidates were found in the experiment that shows that our approach to finding special celestial bodies can be feasible in LAMOST.

  2. Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration.

    Science.gov (United States)

    Ding, Kun; Eaton, Lucia; Bowley, Diana; Rieser, Matthew; Chang, Qing; Harris, Maria C; Clabbers, Anca; Dong, Feng; Shen, Jikui; Hackett, Sean F; Touw, Debra S; Bixby, Jacqueline; Zhong, Suju; Benatuil, Lorenzo; Bose, Sahana; Grinnell, Christine; Preston, Gregory M; Iyer, Ramesh; Sadhukhan, Ramkrishna; Marchie, Susan; Overmeyer, Gary; Ghayur, Tariq; van Riet, Deborah A; Tang, Shibo; Campochario, Peter A; Gu, Jijie

    Exudative age-related macular degeneration (AMD) is the most common cause of moderate and severe vision loss in developed countries. Intraocular injections of vascular endothelial growth factor (VEGF or VEGF-A)-neutralizing proteins provide substantial benefit, but frequent, long-term injections are needed. In addition, many patients experience initial visual gains that are ultimately lost due to subretinal fibrosis. Preclinical studies and early phase clinical trials suggest that combined suppression of VEGF and platelet-derived growth factor-BB (PDGF-BB) provides better outcomes than suppression of VEGF alone, due to more frequent regression of neovascularization (NV) and suppression of subretinal fibrosis. We generated a dual variable domain immunoglobulin molecule, ABBV642 that specifically and potently binds and neutralizes VEGF and PDGF-BB. ABBV642 has been optimized for treatment of exudative AMD based on the following design characteristics: 1) high affinity binding to all VEGF-A isoforms and both soluble and extracellular matrix (ECM)-associated PDGF-BB; 2) potential for extended residence time in the vitreous cavity to decrease the frequency of intraocular injections; 3) rapid clearance from systemic circulation compared with molecules with wild type Fc region for normal FcRn binding, which may reduce the risk of systemic complications; and 4) low risk of potential effector function. The bispecificity of ABBV642 allows for a single injection of a single therapeutic agent, and thus a more streamlined development and regulatory path compared with combination products. In a mouse model of exudative AMD, ABBV642 was observed to be more effective than aflibercept. ABBV642 has potential to improve efficacy with reduced injection frequency in patients with exudative AMD, thereby reducing the enormous disease burden for patients and society.

  3. 激变变星及相关天体的与近红外电离钙三重线的光谱分析%Spectroscopy around and Ca II Triplet of Cataclysmic Variables and Related Objects

    Institute of Scientific and Technical Information of China (English)

    刘学富; 陈阳; 黄河

    2000-01-01

    给出了1997年4月15日至17日在北京天文台用2.16 m望远镜卡焦光谱仪观测获得的6颗激变变星 (AB Boo, UX UMa, T CrB, AH Her, Z Cam 和 V426 Oph) 及3颗相关天体(UMa3, EG UMa 和 Leo3)的CCD光谱, 并同时拍摄了5颗晚型星(3 Dra, Vir, Leo, 34 Boo 和36Com) 的CCD 光谱, 作为晚型星参考谱. 测量了观测样本星的和近红外Ca II的三重线(8498, 8542和 8662)的等值宽度(EW),谱线半极大全宽(FWHM)和视向速度(Vr), 并分析了这些星的活动性.%In this paper, some CCD spectra of 6 cataclysmic variables: AB Boo, T CrB, UX UMa, AH Her, Z Cam, V426 Oph and 3 related objects: Leo3, UMa3 and EG UMa are presented. We also observed 5 late-type stars: 3 Dra, Vir, Leo, 34 Boo, and 36 Com in order to provide comparison with the late-type component of the program systems. The observations were made using the 2.16 m telescope of Bejing Observatory with a Cassergrain spectrograph on 1997—04—15/17 at the Xinglong Station. The CCD spectra were obtained with a low resolution and a dispersion of 1.2/pixel. The spectral region covered is from 5920 to 7072, and from 7950 to 9180 for all the program stars and only 3390—8380 for AH Her. Representative spectra are given for each object. The equivalent width (EW) and FWHM of and CaII triplet lines were determined. The radial velocities for 9 program stars were also determined. Implications of our results are discussed.

  4. FITDisk: Cataclysmic Variable Accretion Disk Demonstration Tool

    Science.gov (United States)

    Wood, Matthew A.; Dolence, J.

    2013-05-01

    FITDisk models accretion disk phenomena using a fully three-dimensional hydrodynamics calculation, and data can either be visualized as they are computed or stored to hard drive for later playback at a fast frame rate. Simulations are visualized using OpenGL graphics and the viewing angle can be changed interactively. Pseudo light curves of simulated systems can be plotted along with the associated Fourier amplitude spectrum. It provides an easy to use graphical user interface as well as 3-D interactive graphics. The code computes the evolution of a CV accretion disk, visualizes results in real time, records and plays back simulations, and generates and plots pseudo light curves and associated power spectra.

  5. The Magnetospheric Boundary in Cataclysmic Variables

    Directory of Open Access Journals (Sweden)

    Hellier Coel

    2014-01-01

    During outbursts, when the accretion flow increases by orders of magnitude, the disk pushes the magnetosphere inwards, and appears to feed field lines over a much greater range of magnetic azimuth. The non-equilibrium outburst behaviour shows an even richer phenomenology than in quiescence, adding DNOs and QPOs into the mix.

  6. BB

    DEFF Research Database (Denmark)

    Jensen, Boris Brorman

    2003-01-01

    Udstillingskatalog fra udstillingen "Image City - Formal and Informal Networks". Kunstakademiets Arkitektskole 8. august-14. september 2003......Udstillingskatalog fra udstillingen "Image City - Formal and Informal Networks". Kunstakademiets Arkitektskole 8. august-14. september 2003...

  7. Optical Studies of Twenty Longer-Period Cataclysmic Binaries

    CERN Document Server

    Thorstensen, John R; Skinner, Julie N

    2010-01-01

    We obtained time-series radial velocity spectroscopy of twenty cataclysmic variable stars, with the aim of determining orbital periods P_orb. All of the stars reported here prove to have P_orb > 3.5 h. For sixteen of the stars, these are the first available period determinations, and for the remaining four (V709 Cas, AF Cam, V1062 Tau, and RX J2133+51) we use new observations to improve the accuracy of previously-published periods. Most of the targets are dwarf novae, without notable idiosyncracies. Of the remainder, three (V709 Cas, V1062 Tau, and RX J2133+51) are intermediate polars (DQ Her stars); one (IPHAS 0345) is a secondary-dominated system without known outbursts, similar to LY UMa; one (V1059 Sgr) is an old nova; and two others (V478 Her and V1082 Sgr) are long-period novalike variables. The stars with new periods are IPHAS 0345 (0.314 d); V344 Ori (0.234 d); VZ Sex (0.149 d); NSVS 1057+09 (0.376 d); V478 Her (0.629 d); V1059 Sgr (0.286 d); V1082 Sgr (0.868 d); FO Aql (0.217 d); V587 Lyr (0.275 d); ...

  8. Photometric CCD observations of four Pre-cataclysmic binary candidates

    Science.gov (United States)

    Hinojosa, R.; Vogt, N.; Colque, Juan Pablo

    We present preliminary results of differential photometric observations of Abell 65, HZ 9, GD 1401 and BPM 46460, obtained between September and December 2006 with the 42 cm telescope of the Cerro Armazones Observatory which belongs to the Universidad Catolica del Norte, Antofagasta. All four stars are close red dwarf/white dwarf binaries which could have formed be recent common envelope events. In two of the four cases we detected (or confirmed) significant variability. In one of them, the central star of a planetary nebula Abell 65, we confirmed the rather strong photometric variability with a period very near to 24 hours (Bond and Livio, 1990). In the white dwarf binary HZ9 we detected, for the first time, photometric variations with a period near 0.58 days which corresponds to the known orbital period (Lanning and Pesch, 1981; Stauffer, 1987). The amplitude of this variation is 0.08 mag, it probably refers to reflection of the white dwarf radiation on the surface of the red companion. - These observations are part of a larger on-going project which pretends to identify and to study pre-cataclysmic binaries by means of photometric and spectroscopic methods and to improve, this way, the hitherto poor statistics on the properties of these interesting stars.

  9. History of the Terminal Cataclysm Concept: A Cataclysm That Never Happened?

    Science.gov (United States)

    Hartmann, William K.

    2014-11-01

    The “terminal cataclysm” (or “late heavy bombardment”) concept of the last 40 years exhibits curious epistemology, with changing definitions and inconsistent evidence.Pre-Apollo evidence showed that the impact rate prior to ~3.5 Ga ago averaged ~150x the post-mare rate [1]. In 1973-4, Tera et al. [2,3] introduced the term “terminal cataclysm,” widespread metamorphism ~3.9 Ga ago, possibly caused by the Imbrium impact [3, p.15], or more likely by “formation of several major basins [in a] short time interval (less than 0.2AE)” [3, p.18]. In 1990, Ryder [4] reported a strong spike in ages for Apollo impact melt rocks ~3.8-4.0 Ga ago, and proposed this as proof that a Moon-wide cataclysmic bombardment occurred at that time, with no earlier cratering. Three inconsistencies soon appeared. (1) In 2002, Cohen et al. [5, also 2002 & 2005] dated lunar meteorite clasts (aiming at non-Apollo lunar regions) and found no spike or anomaly at 3.9 Ga. (Yet they inferred “support for the lunar cataclysm hypothesis.”) (2) The Nice model in early 2000s predicted many planetesimals scattered from the outer to the inner Solar System [6], with a plausible (unconstrained) date of 3.9 Ga - but asteroidal meteorite impact melt clasts (like lunar meteorites) show no spike at 3.9. (3) Meanwhile, reports of pre-4.0 impact melts have increased among upland breccia clasts. Nice and Grand Tack modelers have introduced “sawteeth” spikes before 4.0 and gradual declines after 3.8 (both had been proposed earlier), thus softening the “cataclysm” spike. A 2014 model by Marchi, Bottke, Morbidelli, Kring, et al. [7] illustrates a curve of impact flux vs. time, 4.4 to 3.5 Ga, showing no spike at 3.9 Ga - signaling a possible demise of the terminal cataclysm hypothesis. [1] Hartmann W.K. 1966. Icarus 5, 406-418[2] Tera F. et al. 1973. LPSC abstract, p. 723[3] Tera F. et al. 1974. EPSK 22, 1-21[4] Ryder G. 1990. EOS 71, 313[5] Cohen B., Swindle T., Kring D. 2000. Science 290

  10. The Lunar Cataclysm and How LRO Can Help Test It

    Science.gov (United States)

    Cohen, Barbara A.

    2009-01-01

    One of the important outstanding goals of lunar science is understanding the bombardment history of the Moon and calibrating the impact flux curve for extrapolation to the Earth and other terrestrial planets. The "terminal lunar cataclysm," a brief but intense period of bombardment about 3.9 billion years ago, is of particular scientific interest. Radiometric dating of lunar impact-melt rocks forms the backbone of the lunar cataclysm hypothesis. A histogram of precise age determinations of impact-melt rocks shows the characteristics of the classic formulation of the lunar cataclysm hypothesis: a sharp peak at 3.9 Ga, a steep decline after 3.9 Ga perhaps only 20-200 Myr long, and few rocks of impact origin prior to 4.0 Ga.

  11. Hard X-ray Observations of Magnetic Cataclysmic Variables

    CERN Document Server

    Singh, K P; Mukerjee, K; Barrett, P; Schlegel, E M

    2003-01-01

    Hard X-ray light curves and spectral parameters from our analysis of X-ray data of five AM Her type systems - V2301 Oph, V1432 Aql, EP Draconis, GG Leonis, V834 Cen, and one intermediate polar - TV Col, observed using the Rossi X-ray Timing Explorer satellite are presented. A new improved ephemeris has been derived for V2301 Oph using the mid-eclipse timings. Average intensity variations, without any change of shape of the light curve or hardness ratio, are observed on timescales of a few days to a few months in V2301 Oph. V1432 Aql shows erratic variations on a timescale of a day, at least 2 sharp dips near orbital phases 0.35 and 0.5, and a total eclipse. Hard X-ray eclipses are also reported in EP Dra and GG Leo. V834 Cen shows intensity variations on yearly timescale and is found to be in a low state in 2002. In TV Col, a binary orbital modulation at 5.5h, in addition to the spin period of 1910s, is reported for the first time. Maximum spectral temperatures in Polars have been determined and used to estim...

  12. Evolutionary Grids of Accreting White Dwarf Companions in Cataclysmic Variables

    Science.gov (United States)

    Benjamin, J.; Jensen, M.; Nadeau, S.; Nelson, L. A.

    2003-12-01

    We analyze the evolution of accreting white dwarfs in binary systems for a wide range of initial conditions. Specifically, evolutionary tracks are calculated for CO white dwarfs with masses in the range of 0.6 - 1.3 solar masses and accreting H-rich gas at rates of between 10-6 to 10-10 solar masses per year. Since the white dwarfs in these binaries could be very young or very old at the onset of mass transfer we simulated this possibility by investigating the evolution for a large range of internal temperatures. Thus most of the sequences generated were not thermally relaxed at the onset of mass transfer (and the thermonuclear flashes were not cyclic). We discuss the temporal dependence of the interior properties (envelope readjustment on a thermal timescale and compressional heating) on the initial conditions. Particular attention is paid to the white dwarfs accretors that remained small (relative to the Roche lobe radius) during the shell flash event. Finally, we use the results of these models to comment on the observed properties of Supersoft X-ray sources. This research was supported in part by funds from the Natural Sciences and Engineering Research Council (Canada).

  13. Superhumps in Cataclysmic Binaries. XXV. q_crit, epsilon(q), and Mass-Radius

    CERN Document Server

    Patterson, J; Harvey, D; Fried, R; Rea, R; Monard, B; Cook, L; Skillman, D R; Vanmunster, T; Bolt, G; Armstrong, E; McCormick, J; Krajci, T; Jensen, L; Gunn, J; Butterworth, N D; Foote, J; Bos, M; Masi, G; Warhurst, P; Patterson, Joseph; Kemp, Jonathan; Harvey, David; Fried, Robert; Rea, Robert; Monard, Berto; Cook, Lewis; Skillman, David; Vanmunster, Tonny; Bolt, Greg; Armstrong, Eve; Cormick, Jennie Mc; Krajci, Thomas; Jensen, Lasse; Gunn, Jerry; Butterworth, Neil; Foote, Jerry; Bos, Marc; Masi, Gianluca; Warhurst, Paul

    2005-01-01

    We report on successes and failures in searching for positive superhumps in cataclysmic variables, and show the superhumping fraction as a function of orbital period. Basically, all short-period systems do, all long-period systems don't, and a 50% success rate is found at P_orb=3.1+-0.2 hr. We can use this to measure the critical mass ratio for the creation of superhumps. With a mass-radius relation appropriate for cataclysmic variables, and an assumed mean white-dwarf mass of 0.75 M_sol, we find a mass ratio q_crit=0.35+-0.02. We also report superhump studies of several stars of independently known mass ratio: OU Virginis, XZ Eridani, UU Aquarii, and KV UMa (= XTE J1118+480). The latter two are of special interest, because they represent the most extreme mass ratios for which accurate superhump measurements have been made. We use these to improve the epsilon(q) calibration, by which we can infer the elusive q from the easy-to-measure epsilon (the fractional period excess of P_superhump over P_orb). This rela...

  14. Detection of accretion X-rays from QS Vir: cataclysmic or a lot of hot air?

    CERN Document Server

    Matranga, Marco; Kashyap, Vinay; Steeghs, Danny

    2012-01-01

    An XMM-Newton observation of the nearby "pre-cataclysmic" short-period (P_orb = 3.62 hr) binary QS Vir (EC 13471-1258) revealed regular narrow X-ray eclipses when the white dwarf passed behind its M2-4 dwarf companion. The X-ray emission provides a clear signature of mass transfer and accretion onto the white dwarf. The low-resolution XMM-Newton EPIC spectra are consistent with a cooling flow model and indicate an accretion rate of Mdot= 1.7\\times10^-13M\\odot/yr. At 48 pc distant, QS Vir is then the second nearest accreting cataclysmic variable known, with one of the lowest accretion rates found to date for a non-magnetic system. To feed this accretion through a wind would require a wind mass loss rate of Mdot ~ 2 \\times 10^-12M\\odot/yr if the accretion efficiency is of the order of 10%. Consideration of likely mass loss rates for M dwarfs suggests this is improbably high and pure wind accretion unlikely. A lack of accretion disk signatures also presents some difficulties for direct Roche lobe overflow. We sp...

  15. A Trip to the Cataclysmic Binary Zoo: Detailed Follow-up of 35 Recently Discovered Systems

    Science.gov (United States)

    Thorstensen, John R.; Alper, Erek H.; Weil, Kathryn E.

    2016-12-01

    We report follow-up studies of 35 recently discovered cataclysmic variables (CVs), 32 of which were found in large, automated synoptic sky surveys. The objects were selected for observational tractability. For 34 of the objects, we present mean spectra and spectroscopic orbital periods, and for one more we give an eclipse-based period. Thirty-two of the period determinations are new, and three of these refine published estimates based on superhump periods. The remaining three of our determinations confirm previously published periods. Twenty of the stars are confirmed or suspected dwarf novae with periods shorter than 3 hr, but we also find three apparent polars (AM Her stars) and six systems with P\\gt 5 {hr}. Five of these systems have secondary stars visible in their spectra, from which we estimate distances when possible. The orbital period distribution of this sample is very similar to that of previously discovered CVs.

  16. 裸妆圣品 BB Cream

    Institute of Scientific and Technical Information of China (English)

    阿饼

    2009-01-01

    夏天里清新自然的裸妆越来越热门,可美眉们都希望能拥有自然面剔透的皮肤的同时,也能适当遮盖脸上的小雀斑和痘痘瑕疵,还不需要每天涂着厚厚的粉底出门,这么多的要求能同时满足的,无疑只有被称为“裸妆圣品”的BB Cream。

  17. OCULAR INJURIES CAUSED BY BB GUN

    Directory of Open Access Journals (Sweden)

    M.S. Farahvash

    1999-08-01

    Full Text Available in ordere to determine the prognosis of perforating eye injuries caused hy BB guns in our patients, the"nvisual and anatomic results of 14 patients with gun injuries seen between September 1996 and February 1998 in Farafti Hospital and private office in Tehran were reviewed. Five patients liad nonn erf orating eye injuries. All perforated eyes underwent scleral buckling, tenseclomy, vitrectomy ami silicone injection. All injured iyes had a visual acuity of light perception or better at presentation. Among 9 cases of perforating injuries. 7 had doable and 2 had single perforation. All patients had a final.

  18. ATLAS VH(bb) Run II Search

    CERN Document Server

    Buzatu, Adrian; The ATLAS collaboration

    2016-01-01

    The Higgs boson discovered at the LHC in 2012 has been observed coupling directly to W and Z bosons and to tau leptons, and indirectly to top quarks. In order to probe if it is indeed the particle predicted by the Standard Model, direct couplings of the Higgs boson to quarks must also be measured. The Higgs boson decays most often to a pair of bottom quarks (with a branching ratio of 58%). When the Higgs boson is produced alone in gluon-gluon fusion, the signal in this decay mode is overwhelmed by the regular multi-jet background. By requiring the Higgs boson to be produced in association with a vector boson V (W or Z), which is further required to decay leptonically, data events can be selected using charged-lepton or missing transverse energy triggers. The Tevatron experiments presented combined results showing evidence for the VH(H to bb) process at a significance level of about 3 standard deviations, while the combined LHC results from Run II data show a 2.6 standard deviation evidence for the H to bb dec...

  19. Multiple time scales in cataclysmic binaries. The low-field magnetic dwarf nova DO Draconis

    CERN Document Server

    Andronov, I L; Han, W; Kim, Y; Yoon, J -N

    2008-01-01

    We study the variability of the cataclysmic variable DO Dra, on time-scales of between minutes and decades. The characteristic decay time dt/dm=0.902(3) days/mag was estimated from our 3 nights of CCD R observations. The quiescent data show a photometric wave with a cycle about 303(15)d. We analyzed the profile of the composite (or mean) outburst. We discovered however, that a variety of different outburst heights and durations had occurred, contrary to theoretical predictions. With increasing maximum brightness, we find that the decay time also increases; this is in contrast to the model predictions, which indicate that outbursts should have a constant shape. This is interpreted as representing the presence of outburst-to-outburst variability of the magnetospheric radius. A presence of a number of missed weak narrow outbursts is predicted from this statistical relationship. A new type of variability is detected, during 3 subsequent nights in 2007: periodic (during one nightly run) oscillations with rapidly-d...

  20. Methane and trichloroethylene oxidation by an estuarine methanotroph, Methylobacter sp. strain BB5.1.

    OpenAIRE

    Smith, K. S.; Costello, A. M.; Lidstrom, M E

    1997-01-01

    An estuarine methanotroph was isolated from sediment enrichments and designated Methylobacter sp. strain BB5.1. In cells grown on medium with added copper, oxidation of methane and trichloroethylene occurred with similar Ks values, but the Vmax for trichloroethylene oxidation was only 0.1% of the methane oxidation Vmax. Cells grown on low-copper medium did not oxidize trichloroethylene and showed a variable rate of methane oxidation.

  1. Bb4l event generator, interferences and off-shell effects

    CERN Document Server

    Peyruchat, Leo Paul

    2017-01-01

    Proton-proton collisions happening in LHC create lots of data. To understand the underlying physics behind these events, the real data must be compared to simulated events. A new generator,called the bb4l model, is able to simulate collisions happening in LHC with new interesting features regarding process creating two W bosons and two b quarks. One of them is that it takes interferences between different processes into account. Such effects have always been neglected in the case of top pair or single top production, but with the increasing sensitivity of the detectors it is becoming important to know precisely their amplitude. The goal of this study is to separate events generated with bb4l into different categories, and then to look at many variables and look for differences between categories.

  2. DETECTION OF ACCRETION X-RAYS FROM QS Vir: CATACLYSMIC OR A LOT OF HOT AIR?

    Energy Technology Data Exchange (ETDEWEB)

    Matranga, Marco; Drake, Jeremy J.; Kashyap, Vinay [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Steeghs, Danny, E-mail: mmatranga@cfa.harvard.edu [Department of Physics, University of Warwick, Coventry CV4 7AL (United Kingdom)

    2012-03-10

    An XMM-Newton observation of the nearby 'pre-cataclysmic' short-period (P{sub orb} = 3.62 hr) binary QS Vir (EC 13471-1258) revealed regular narrow X-ray eclipses when the white dwarf passed behind its M2-4 dwarf companion. The X-ray emission provides a clear signature of mass transfer and accretion onto the white dwarf. The low-resolution XMM-Newton EPIC spectra are consistent with a cooling flow model and indicate an accretion rate of M-dot = 1.7 Multiplication-Sign 10{sup -13} M{sub sun} yr{sup -1}. At 48 pc distant, QS Vir is then the second nearest accreting cataclysmic variable known, with one of the lowest accretion rates found to date for a non-magnetic system. To feed this accretion through a wind would require a wind mass-loss rate of M-dot {approx}2 Multiplication-Sign 10{sup -12} M{sub sun} yr{sup -1} if the accretion efficiency is of the order of 10%. Consideration of likely mass-loss rates for M dwarfs suggests this is improbably high and pure wind accretion unlikely. A lack of accretion disk signatures also presents some difficulties for direct Roche lobe overflow. We speculate that QS Vir is on the verge of Roche lobe overflow, and that the observed mass transfer could be supplemented by upward chromospheric flows on the M dwarf, analogous to spicules and mottles on the Sun, that escape the Roche surface to be subsequently swept up into the white dwarf Roche lobe. If so, QS Vir would be in a rare evolutionary phase lasting only a million years. The X-ray luminosity of the M dwarf estimated during primary eclipse is L{sub X} = 3 Multiplication-Sign 10{sup 28} erg s{sup -1}, which is consistent with that of rapidly rotating 'saturated' K and M dwarfs.

  3. Curious Variables Experiment (CURVE). IX Draconis - a Clue for Understanding Evolution of Cataclysmic Variable Stars

    CERN Document Server

    Olech, A; Mularczyk, K; Kedzierski, P; Wisniewski, M; Stachowski, G

    2004-01-01

    We report extensive photometry of frequently outbursting dwarf nova IX Draconis. During five months of observations the star went into three superoutbursts and seven ordinary outbursts. This allowed us to determine its supercycle and cycle lengths as equal to 54 +/- 1 and 3.1 +/- 0.1 days, respectively. During the Sep 2003 superoutburst, which had the best observational coverage, IX Dra displayed clear superhumps with a period of Psh=0.066968(17) days. This period was constant during the whole superoutburst. Another period, which was clearly present in the light curve of IX Dra in superoutburst, had a value of 0.06646(6) days and we interpret it as the orbital period of the binary. Thus IX Dra is the first SU UMa star showing orbital modulation during the entire superoutburst. The beat between these two periods is the main cause of an unusual phase reversal of superhumps - a phenomenon which was previously observed in ER UMa. If our interpretation of the second periodicity is correct, IX Dra has an extremely ...

  4. EST Table: BB985913 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ar to putative lysosomal glucocerebrosidase [Tribolium castaneum] 10/08/28 30 %/249 aa FBpp0129766|DereGG112...EDICTED: similar to putative lysosomal glucocerebrosidase [Tribolium castaneum] BB985877 MSV3 ...

  5. 2MASSJ22560844+5954299: the newly discovered cataclysmic star with the deepest eclipse

    CERN Document Server

    Kjurkchieva, D; Dimitrov, D; Groebel, R; Ibryamov, S; Nikolov, G

    2015-01-01

    Context: The SW Sex stars are assumed to represent a distinguished stage in CV evolution, making it especially important to study them. Aims: We discovered a new cataclysmic star and carried out prolonged and precise photometric observations, as well as medium-resolution spectral observations. Modelling these data allowed us to determine the psysical parameters and to establish its peculiarities. Results: The newly discovered vataclysmic variable 2MASSJ22560844+5954299 shows the deepest eclipse amongst the known nova-like stars. It was reproduced by totally covering a very luminous accretion disk by a red secondary component. The temperature distribution of the disk is flatter than that of steady-state disk. The target is unusual with the combination of a low mass ratio q~1.0 (considerably below the limit q=1.2 of stable mass transfer of CVs) and an M-star secondary. The intensity of the observed three emission lines, H_alpha, He 5875, and He 6678, sharply increases around phase 0.0, accompanied by a Doppler ...

  6. The autophagy-related genes BbATG1 and BbATG8 have different functions in differentiation, stress resistance and virulence of mycopathogen Beauveria bassiana.

    Science.gov (United States)

    Ying, Sheng-Hua; Liu, Jing; Chu, Xin-Ling; Xie, Xue-Qin; Feng, Ming-Guang

    2016-05-20

    Autophagy-related proteins play significantly different roles in eukaryotes. In the entomopathogenic fungus Beauveria bassiana, autophagy is associated with fungal growth and development. BbATG1 (a serine/threonine protein kinase) and BbATG8 (a ubiquitin-like protein) have similar roles in autophagy, but different roles in other processes. Disruption mutants of BbATG1 and BbATG8 had impaired conidial germination under starvation stress. The mutant ΔBbATG8 exhibited enhanced sensitivity to oxidative stress, while a ΔBbATG1 mutant did not. BbATG1 and BbATG8 showed different roles in spore differentiation. The blastospore yield was reduced by 70% and 92% in ΔBbATG1 and ΔBbATG8 mutants, respectively, and the double mutant had a reduction of 95%. Conidial yield was reduced by approximately 90% and 50% in ΔBbATG1 and ΔBbATG8 mutants, respectively. A double mutant had a reduction similar to ΔBbATG1. Additionally, both BbATG1 and BbATG8 affected the levels of conidial protein BbCP15p required for conidiation. The virulence of each autophagy-deficient mutant was considerably weakened as indicated in topical and intrahemocoel injection assays, and showed a greater reduction in topical infection. However, BbATG1 and BbATG8 had different effects on fungal virulence. Our data indicate that these autophagy-related proteins have different functions in fungal stress response, asexual development and virulence.

  7. EST Table: BB990886 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB990886 E_ET_MSV3_04C04_R_0 11/12/09 GO hit GO:0016491(oxidoreductase activity)|GO:0055114(oxidation reduct...ion) 10/09/28 low homology 10/08/28 n.h 10/08/28 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB990886 MSV3 ...

  8. A Trip to the Cataclysmic Binary Zoo: Detailed Follow-Up of 35 Recently-Discovered Systems

    CERN Document Server

    Thorstensen, John R; Weil, Kathryn E

    2016-01-01

    We report follow-up studies of 35 recently-discovered cataclysmic variables (CVs), 32 of which were found in large, automated synoptic sky surveys. The objects were selected for observational tractability. For 34 of the objects we present mean spectra and spectroscopic orbital periods, and for one more we give an eclipse-based period. Thirty-two of the period determinations are new, and three of these refine published estimates based on superhump periods. The remaining three of our determinations confirm previously published periods. Twenty of the stars are confirmed or suspected dwarf novae with periods shorter than 3 hours, but we also find three apparent polars (AM Her stars), and six systems with P > 5 h, five of which have secondary stars visible in their spectra, from which we estimate distances when possible. The orbital period distribution of this sample is very similar to that of previously discovered CVs.

  9. Selective method for identification and quantification of Bifidobacterium animalis subspecies lactis BB-12 (BB-12) from the gastrointestinal tract of healthy volunteers ingesting a combination probiotic of BB-12 and Lactobacillus rhamnosus GG.

    Science.gov (United States)

    Poutsiaka, D D; Mahoney, I J; McDermott, L A; Stern, L L; Thorpe, C M; Kane, A V; Baez-Giangreco, C; McKinney, J; Davidson, L E; Leyva, R; Goldin, B; Snydman, D R

    2017-05-01

    To develop a novel validated method for the isolation of Bifidobacterium animalis ssp. lactis BB-12 (BB-12) from faecal specimens and apply it to studies of BB-12 and Lactobacillus rhamnosus GG (LGG) recovered from the healthy human gastrointestinal (GI) tract. A novel method for isolating and enumerating BB-12 was developed based on its morphologic features of growth on tetracycline-containing agar. The method identified BB-12 correctly from spiked stool close to 100% of the time as validated by PCR confirmation of identity, and resulted in 97-104% recovery of BB-12. The method was then applied in a study of the recovery of BB-12 and LGG from the GI tract of healthy humans consuming ProNutrients(®) Probiotic powder sachet containing BB-12 and LGG. Viable BB-12 and LGG were recovered from stool after 21 days of probiotic ingestion compared to baseline. In contrast, no organisms were recovered 21 days after baseline in the nonsupplemented control group. We demonstrated recovery of viable BB-12, using a validated novel method specific for the isolation of BB-12, and LGG from the GI tract of healthy humans who consumed the probiotic supplement. This method will enable more detailed and specific studies of BB-12 in probiotic supplements, including when in combination with LGG. © 2017 The Society for Applied Microbiology.

  10. A magnetic accretion switch in pre-cataclysmic binaries?

    CERN Document Server

    Drake, Jeremy J; Takei, Dai; Gaensicke, Boris

    2014-01-01

    We have investigated the mass accretion rate implied by published surface abundances of Si and C in the white dwarf component of the 3.62 hr period pre-cataclysmic binary and planet host candidate QS Vir (DA+M2-4). Diffusion timescales for gravitational settling imply $\\dot{M} \\sim 10^{-16}M_\\odot$ yr$^{-1}$ for the 1999 epoch of the observations, which is three orders of magnitude lower than measured from a 2006 {\\it XMM-Newton} observation. This is the first time that large accretion rate variations have been seen in a detached pre-CV. A third body in a 14 yr eccentric orbit suggested in a recent eclipse timing study is too distant to perturb the central binary sufficiently to influence accretion. A hypothetical coronal mass ejection just prior to the {\\it XMM-Newton} observation might explain the higher accretion rate, but the implied size and frequency of such events appear too great. We suggest accretion is most likely modulated by a magnetic cycle on the secondary acting as a wind "accretion switch", a ...

  11. A New Damage Detection Method: Big Bang-Big Crunch (BB-BC Algorithm

    Directory of Open Access Journals (Sweden)

    Zahra Tabrizian

    2013-01-01

    Full Text Available The present paper aims to explore damage assessment methodology based on the changes in dynamic parameters properties of vibration of a structural system. The finite-element model is used to apply at an element level. Reduction of the element stiffness is considered for structural damage. A procedure for locating and quantifying damaged areas of the structure based on the innovative Big Bang-Big Crunch (BB-BC optimization method is developed for continuous variable optimization. For verifying the method a number of damage scenarios for simulated structures have been considered. For the purpose of damage location and severity assessment the approach is applied in three examples by using complete and incomplete modal data. The effect of noise on the accuracy of the results is investigated in some cases. A great unbraced frame with a lot of damaged element is considered to prove the ability of proposed method. More over BB-BC optimization method in damage detection is compared with particle swarm optimizer with passive congregation (PSOPC algorithm. This work shows that BB-BC optimization method is a feasible methodology to detect damage location and severity while introducing numerous advantages compared to referred method.

  12. Contrast enhancement of intracranial lesions at 1.5 T: comparison among 2D spin echo, black-blood (BB) Cube, and BB Cube-FLAIR sequences

    Energy Technology Data Exchange (ETDEWEB)

    Im, SungWoon; Ashikaga, Ryuichiro; Yagyu, Yukinobu; Hyodo, Tomoko; Imaoka, Izumi; Kumano, Seishi; Ishii, Kazunari; Murakami, Takamichi [Kinki University Faculty of Medicine, Department of Radiology, Osaka-Sayama, Osaka (Japan); Wakayama, Tetsuya; Miyoshi, Mitsuharu [GE Healthcare Japan, MR Applications and Workflow, Asia Pacific, Hino, Tokyo (Japan)

    2015-11-15

    The purpose of this study was to investigate the usefulness of T1W black-blood Cube (BB Cube) and T1W BB Cube fluid-attenuated inversion recovery (BB Cube-FLAIR) sequences for contrast-enhanced brain imaging, by evaluating flow-related artefacts, detectability, and contrast ratio (CR) of intracranial lesions among these sequences and T1W-SE. Phantom studies were performed to determine the optimal parameters of BB Cube and BB Cube-FLAIR. A clinical study in 23 patients with intracranial lesions was performed to evaluate the usefulness of these two sequences for the diagnosis of intracranial lesions compared with the conventional 2D T1W-SE sequence. The phantom study revealed that the optimal parameters for contrast-enhanced T1W imaging were TR/TE = 500 ms/minimum in BB Cube and TR/TE/TI = 600 ms/minimum/300 ms in BB Cube-FLAIR imaging. In the clinical study, the degree of flow-related artefacts was significantly lower in BB Cube and BB Cube-FLAIR than in T1W-SE. Regarding tumour detection, BB Cube showed the best detectability; however, there were no significant differences in CR among the sequences. At 1.5 T, contrast-enhanced BB Cube was a better imaging sequence for detecting brain lesions than T1W-SE or BB Cube-FLAIR. (orig.)

  13. Search for ttH(H to bb)

    CERN Document Server

    The ATLAS collaboration

    2009-01-01

    For a light Higgs boson, with mH ≤ 135 GeV, the largest decay mode is H to bb. Events where the Higgs boson is produced in association with a tt pair manifest a distinct signature due to the presence of two W bosons and four b quarks. Topological and kinematical quantities are used to reconstruct the tt system. The identification of an additional bb pair from the Higgs boson decay is used to further reduce the background. In this analysis we focus on the sensitivity to a light Standard Model Higgs boson with the ATLAS detector in the channel ttH(H → bb) using the semi-leptonic final state with 30fb−1 of integrated luminosity. The relevant backgrounds to the channel are investigated and the impact of their associated systematic uncertainties is explored.

  14. 献给宝贝 Love & BB Cream

    Institute of Scientific and Technical Information of China (English)

    王冉; 钟伟波

    2010-01-01

    BB Cream有樱花味、蜜桃味、牛奶味……别误会,我不是在说宠物食品,更不是在说化妆品,小编这次向你推荐的,是萃取天然精华制作的赑赑幼犬沐浴乳。温和的配方、细腻的泡沫、香香的味道,BB Cream是妈妈献给宝贝的爱的礼物。

  15. EST Table: BB991540 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB991540 E_ET_MSV3_15F09_R_0 10/09/28 37 %/160 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 n.h 10/08/28 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB992168 MSV3 ...

  16. BB mode angular power spectrum of CMB from massive gravity

    CERN Document Server

    Malsawmtluangi, N

    2016-01-01

    The primordial massive gravitational waves are placed in the squeezed vacuum state and corresponding $BB$-mode correlation angular power spectrum of the cosmic microwave background is obtained for various slow roll inflation models. The angular power spectrum is compared with the limit of BICEP2/Keck and Planck joint analysis data and the hybrid inflation model is found favorable.

  17. EST Table: BB986378 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB986378 E_ET_MSV3_16H05_F_0 11/12/09 n.h 10/09/28 57 %/111 aa ref|XP_001663157.1| atlas...tin [Aedes aegypti] gb|EAT45634.1| atlastin [Aedes aegypti] 10/08/28 58 %/111 aa FBpp0120409|DanaGF1721

  18. EST Table: BB989557 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB989557 E_ET_psgV_26A01_F_0 10/09/28 100 %/106 aa ref|NP_001119705.1| transformer ...2 isoform A [Bombyx mori] gb|AAT42220.2| transformer-2 protein A [Bombyx mori] 10/08/28 low homology 10/08/2

  19. Perverse equivalences, BB-tilting, mutations and applications

    CERN Document Server

    Ladkani, Sefi

    2010-01-01

    We relate the notions of BB-tilting and perverse derived equivalence at a vertex. Based on these notions, we define mutations of algebras, leading to derived equivalent ones. We present applications to endomorphism algebras of cluster-tilting objects in 2-Calabi-Yau categories and to algebras of global dimension at most 2.

  20. EST Table: BB983310 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB983310 ovS3018H05r 10/09/28 100 %/155 aa dbj|BAF76333.1| ecdysone receptor [Bomby...121308146|emb|CAL25730.1| ecdysone receptor (isoform A) [Tribolium castaneum] NM_001043866 ovS3 ...

  1. EST Table: BB984320 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB984320 ovS3032H12r 10/09/28 100 %/118 aa dbj|BAF76333.1| ecdysone receptor [Bomby...121308146|emb|CAL25730.1| ecdysone receptor (isoform A) [Tribolium castaneum] NM_001043866 ovS3 ...

  2. ON THE POLYCONDENSATION REACTION OF Aa<Bb Cc TYPE

    Institute of Scientific and Technical Information of China (English)

    LI Zesheng; TANG Xinyi; SUN Chiachung; TANG Auchin

    1991-01-01

    For the polycondensation reaction of Aa<Bb Cc type, the sol fraction for post-gel is investigated from probability consideration to approach gelation condition as a limitation. Furthermore, by means of a direct differentiation technique, a recursion formula is proposed for the evaluation of polymer moments in explicit forms for both pre-gel and post-gel.

  3. EST Table: BB986249 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ar to putative lysosomal glucocerebrosidase [Tribolium castaneum] 10/08/28 low homology 10/08/27 35 %/211 aa... %/206 aa gnl|Amel|GB13722-PA 10/09/10 42 %/206 aa gi|91087345|ref|XP_975608.1| PREDICTED: similar to putative lysosomal glucocerebrosidase [Tribolium castaneum] BB985877 MSV3 ...

  4. EST Table: BB986379 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ar to putative lysosomal glucocerebrosidase [Tribolium castaneum] 10/08/28 low homology 10/08/27 35 %/211 aa... %/206 aa gnl|Amel|GB13722-PA 10/09/10 43 %/206 aa gi|91087345|ref|XP_975608.1| PREDICTED: similar to putative lysosomal glucocerebrosidase [Tribolium castaneum] BB985877 MSV3 ...

  5. EST Table: BB985877 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available 13 aa ref|XP_975608.1| PREDICTED: similar to putative lysosomal glucocerebrosidas...el|GB10584-PA 10/09/10 43 %/213 aa gi|91087345|ref|XP_975608.1| PREDICTED: similar to putative lysosomal glucocerebrosidase [Tribolium castaneum] BB985877 MSV3 ...

  6. EST Table: BB991328 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB991328 E_ET_MSV3_12D06_R_0 10/09/28 67 %/189 aa ref|XP_002427369.1| Integrator co...mplex subunit, putative [Pediculus humanus corporis] gb|EEB14631.1| Integrator complex subunit, putative [Pe

  7. EST Table: BB982222 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB982222 ovS3003F07r 10/09/28 52 %/140 aa ref|XP_001606351.1| PREDICTED: similar to... MGC64464 protein [Nasonia vitripennis] 10/08/28 n.h 10/08/27 41 %/136 aa F33H2.6#CE30528#WBGene00009369#sta

  8. EST Table: BB994691 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB994691 E_ET_psgV_31E03_R_0 10/09/28 79 %/279 aa ref|XP_971164.2| PREDICTED: similar to widerborst...89238934|ref|XP_971164.2| PREDICTED: similar to widerborst CG5643-PC [Tribolium castaneum] FS789093 PSV3 ...

  9. EST Table: BB984047 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available se activity)|GO:0016772(transferase activity, transferring phosphorus-containing groups) 10/09/28 n.h 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB984047 ovS3 ...

  10. EST Table: BB992822 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB992822 E_ET_psgV_03F01_R_0 10/09/28 86 %/122 aa ref|NP_001040163.1| ischemia/repe...rfusion inducible protein [Bombyx mori] gb|ABD36179.1| ischemia/reperfusion inducible protein [Bombyx mori

  11. EST Table: BB987724 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987724 E_ET_psgV_03F01_F_0 10/09/28 100 %/239 aa ref|NP_001040163.1| ischemia/rep...erfusion inducible protein [Bombyx mori] gb|ABD36179.1| ischemia/reperfusion inducible protein [Bombyx mori

  12. EST Table: BB986575 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available 91(phosphatase activity) 10/09/28 50 %/137 aa ref|XP_001648676.1| myotubularin [Aedes aegypti] gb|EAT48393.1| myotubular... aa gnl|Amel|GB18689-PA 10/09/10 44 %/134 aa gi|91084687|ref|XP_968830.1| PREDICTED: similar to myotubularin [Tribolium castaneum] BB986575 MSV3 ...

  13. InterProScan Result: BB992742 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB992742 BB992742_5_ORF1 A49726417F584015 PANTHER PTHR12304 INOSINE-URIDINE PREFERRING NUCLEOS...IDE HYDROLASE 2.6e-29 T IPR001910 Inosine/uridine-preferring nucleoside hydrolase ...

  14. Optimal eavesdropping on BB84 without quantum memory

    CERN Document Server

    Bocquet, Aurélien; Alléaume, Romain

    2011-01-01

    We consider the security of the BB84 quantum key distribution protocol when the eavesdropper doesn't have access to a quantum memory. In this case, Eve's most general strategy is to measure her ancilla with an appropriate POVM designed to take advantage of the post-measurement infor- mation that will be released during the sifting phase of the protocol. Memoryless attacks studied in previous works were not optimal because some aspects of the optimization were not considered, here the optimization was done on all possible parameters accessible to Eve. In particular, we show how to optimize the choice of the POVM as a function of the QBER observed by Alice and Bob. This provides us with tight bounds for the secret key rate of BB84 against a memoryless adversary. The maximum QBER for which a secure key can be extracted is increased from 11% (for collective attacks) to 16.7% with the memoryless assumption.

  15. EST Table: BB986646 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB986646 E_ET_MSV3_20D05_F_0 10/09/28 69 %/123 aa ref|XP_001648944.1| dendritic cel...ubunit M; Short=eIF3m gb|EAT44291.1| dendritic cell protein [Aedes aegypti] 10/08/28 64 %/120 aa FBpp0276999...|XP_968265.1| PREDICTED: similar to dendritic cell protein [Tribolium castaneum] FS916297 MSV3 ...

  16. Survival of B. longum Bb-46 in simulated gastrointestinal fluids

    CSIR Research Space (South Africa)

    Thantsha, MS

    2009-01-01

    Full Text Available to different stresses during manufacturing, storage and consumption (Doleyres and Lacroix, 2005). However, probiotic cultures must remain viable in the environment where they act, to enable them to exert beneficial effect on the consumer (Schillinger, 1999... the survival of interpolymer complex encapsulated Bifidobacterium longum Bb-46 in SGF and SIF, and to investigate effects of different modifications of the polymers on bacterial survival. 2. Materials and methods 2.1. Bacterial cultures Bifidobacterium...

  17. EST Table: BB983692 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB983692 ovS3023H08r 10/09/28 100 %/125 aa ref|NP_001040437.1| muscular protein 20 ...[Bombyx mori] gb|ABF51386.1| muscular protein 20 [Bombyx mori] 10/08/28 58 %/116 aa FBpp0235584|DvirGJ21167-...2465.1| PREDICTED: similar to muscular protein 20 [Tribolium castaneum] FS765856 ovS3 ...

  18. EST Table: BB986504 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB986504 E_ET_MSV3_18F03_F_0 10/09/28 53 %/147 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  19. EST Table: BB986790 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB986790 E_ET_MSV3_22C08_F_0 10/09/28 54 %/147 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  20. EST Table: BB987370 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987370 E_ET_MSV3_30C09_F_0 10/09/28 42 %/223 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  1. EST Table: BB987258 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987258 E_ET_MSV3_28G02_F_0 10/09/28 53 %/154 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/126 aa FBpp0173614|DmojGI24397-PA 10/08/27 n.h

  2. EST Table: BB986100 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB986100 E_ET_MSV3_13E10_F_0 10/09/28 53 %/147 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  3. EST Table: BB985196 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB985196 E_ET_MSV3_01H11_F_0 10/09/28 54 %/147 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  4. EST Table: BB985868 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB985868 E_ET_MSV3_10H05_F_0 10/09/28 53 %/154 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 35 %/122 aa FBpp0173614|DmojGI24397-PA 10/08/27 n.h

  5. EST Table: BB985803 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB985803 E_ET_MSV3_10B02_F_0 10/09/28 53 %/147 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  6. EST Table: BB985611 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB985611 E_ET_MSV3_07C12_F_0 10/09/28 60 %/115 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  7. EST Table: BB987479 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987479 E_ET_MSV3_32D08_F_0 10/09/28 48 %/191 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 low homology 10/08/27 n.h 10/09/10 low homology 10/09/10 low homology 10/09/10 n.h FS937505 MSV3 ...

  8. EST Table: BB987146 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987146 E_ET_MSV3_27A12_F_0 10/09/28 42 %/223 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  9. EST Table: BB987050 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987050 E_ET_MSV3_25G01_F_0 10/09/28 42 %/226 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 35 %/122 aa FBpp0173614|DmojGI24397-PA 10/08/27 n.h

  10. EST Table: BB987507 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987507 E_ET_MSV3_32G05_F_0 10/09/28 42 %/222 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h

  11. EST Table: BB986595 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB986595 E_ET_MSV3_19G02_F_0 10/09/28 67 %/137 aa ref|XP_970542.1| PREDICTED: similar to brix...B12626-PA 10/09/10 67 %/137 aa gi|91090402|ref|XP_970542.1| PREDICTED: similar to brix domain-containing protein 2 [Tribolium castaneum] FS911686 MSV3 ...

  12. LS Peg A Low-Inclination SW Sextantis-Type Cataclysmic Binary with High-Velocity Balmer Emission Line Wings

    CERN Document Server

    Taylor, C J; Patterson, J

    1998-01-01

    We present time-resolved spectroscopy and photometry of the bright cataclysmic variable LS Peg (= S193). The Balmer lines exhibit broad, asymmetric wings Doppler-shifted by about 2000 km/s at the edges, while the HeI lines show phase-dependent absorption features strikingly similar to SW Sextantis stars, as well as emission through most of the phase. The CIII/NIII emission blend does not show any phase dependence. From velocities of Halpha emission lines, we determine an orbital period of 0.174774 +/- 0.000003 d (= 4.1946 h), which agrees with Szkody's (1995) value of approximately 4.2 hours. No stable photometric signal was found at the orbital period. A non-coherent quasi-periodic photometric signal was seen at a period of 20.7 +/- 0.3 min. The high-velocity Balmer wings most probably arise from a stream re-impact point close to the white dwarf. We present simulated spectra based on a kinematic model similar to the modified disk-overflow scenario of Hellier & Robinson (1994). The models reproduce the br...

  13. Circumbinary Dust in Magnetic Cataclysmic Variables - Bright State of AM Her

    Science.gov (United States)

    Hoard, Donald; Brinkworth, Carolyn; Howell, Steve; Wachter, Stefanie

    2007-07-01

    Observations by the AAVSO during the past several days of the polar AM Herculis show that it may be leaving the "normal" faint state it has occupied during the past ~2 years, and becoming bright. We observed AM Her with IRAC during GO-3 as part of program 30249. That program also included two medium-impact TOO observations to be triggered to re-observe any target of 30249 that changed brightness state during GO-3 from whatever state it was in when its non-TOO observation for 30249 was made. Unfortunately, those TOOs expired at the end of June, at about the same time that AM Her first started to show an indication that it might be getting bright. So, we are requesting a DDT observation, for the same scientific reasons that the TOO observations were requested (and approved) for program 30249 (to be detailed in a follow-on email to the Spitzer Helpdesk). The target is visible to Spitzer until Dec 2007 - we request the DDT observation during IRAC-43 or IRAC-44, in case the high state is of short duration. Total AOR duration will be ~10 minutes. We have requested that the AAVSO alert its members to intensify observations of AM Her so we can confirm with certainty the rise to bright state within the next few days; in the meantime, please consider this TOO request and notify us if it would be approved. By then, we should know if the rise to bright state is real and should be observed.

  14. V344 Lyrae: A Touchstone SU UMa Cataclysmic Variable in the Kepler Field

    CERN Document Server

    Wood, Matt A; Howell, Steve B; Cannizzo, John K; Smale, Alan P

    2011-01-01

    We report on the analysis of the Kepler short-cadence (SC) light curve of V344 Lyr obtained during 2009 June 20 through 2010 Mar 19 (Q2--Q4). The system is an SU UMa star showing dwarf nova outbursts and superoutbursts, and promises to be a touchstone for CV studies for the foreseeable future. The system displays both positive and negative superhumps with periods of 2.20 and 2.06-hr, respectively, and we identify an orbital period of 2.11-hr. The positive superhumps have a maximum amplitude of ~0.25-mag, the negative superhumps a maximum amplitude of ~0.8 mag, and the orbital period at quiescence has an amplitude of ~0.025 mag. The quality of the Kepler data is such that we can test vigorously the models for accretion disk dynamics that have been emerging in the past several years. The SC data for V344 Lyr are consistent with the model that two physical sources yield positive superhumps: early in the superoutburst, the superhump signal is generated by viscous dissipation within the periodically flexing disk, ...

  15. V344 Lyrae: A Touchstone SU UMa Cataclysmic Variable in the Kepler Field

    OpenAIRE

    2011-01-01

    We report on the analysis of the Kepler short-cadence (SC) light curve of V344 Lyr obtained during 2009 June 20 through 2010 Mar 19 (Q2--Q4). The system is an SU UMa star showing dwarf nova outbursts and superoutbursts, and promises to be a touchstone for CV studies for the foreseeable future. The system displays both positive and negative superhumps with periods of 2.20 and 2.06-hr, respectively, and we identify an orbital period of 2.11-hr. The positive superhumps have a maximum amplitude o...

  16. Kepler Observations of V447 Lyr: An Eclipsing U Gem Cataclysmic Variable

    CERN Document Server

    Ramsay, Gavin; Howell, Steve B; Wood, Matt A; Still, Martin; Barclay, Thomas; Smale, Alan

    2012-01-01

    We present the results of an analysis of data covering 1.5 years of the dwarf nova V447 Lyr. We detect eclipses of the accretion disk by the mass donating secondary star every 3.74 hrs which is the binary orbital period. V447 Lyr is therefore the first dwarf nova in the Kepler field to show eclipses. We also detect five long outbursts and six short outbursts showing V447 Lyr is a U Gem type dwarf nova. We show that the orbital phase of the mid-eclipse occurs earlier during outbursts compared to quiescence and that the width of the eclipse is greater during outburst. This suggests that the bright spot is more prominent during quiescence and that the disk is larger during outburst than quiescence. This is consistent with an expansion of the outer disk radius due to the presence of high viscosity material associated with the outburst, followed by a contraction in quiescence due to the accretion of low angular momentum material. We note that the long outbursts appear to be triggered by a short outburst, which is ...

  17. SDSS J080434.20+510349.2: Cataclysmic Variable Witnessing the Instability Strip?

    CERN Document Server

    Pavlenko, E; Tovmassian, G; Zharikov, S; Kato, T; Katysheva, N; Andreev, M; Baklanov, A; Antonyuk, K; Pit, N; Sosnovskij, A; Shugarov, S

    2011-01-01

    SDSS J080434.20+510349.2 is the 13th dwarf nova containing a pulsating white dwarf. Among the accreting pulsators that have experienced a dwarf novae outburst, SDSS J0804 has the most dramatic history of events within a short time scale: the 2006 outburst with 11 rebrightenings, series of December 2006 - January 2007 mini-outbursts, the 2010 outburst with 6 rebrightenings. Over 2006-2011, SDSS J080434.20+510349.2 in addition to positive 0.060^d superhumps during the outburst and 1-month post-outburst stage, 0.059005^d orbital humps in quiescence, displayed a significant short-term variations with periods P1 = 12.6 min, P2 = 21.7 min, P3 = 14.1 min and P4 = 4.28 min. The 12.6-min periodicity first appeared 7 months after the 2006 outburst and was the most prominent one during the following \\sim 900 days. It was identified as non-radial pulsations of the white dwarf. The period of this pulsations varied within a range of 36 s, and amplitude changed from 0.013m to 0.03m. Simultaneously one could observe the 21.7...

  18. K-Band Spectroscopy of (Pre-)Cataclysmic Variables: Are Some Donor Stars Really Carbon Poor?

    CERN Document Server

    Howell, Steve B; Szkody, Paula; Silvestri, Nicole M

    2010-01-01

    We present a new sample of $K$-band spectral observations for CVs: non-magnetic and magnetic as well as present day and pre CVs. The purpose of this diverse sample is to address the recent claim that the secondary stars in dwarf novae are carbon deficient, having become so through a far more evolved evolution than the current paradigm predicts. Our new observations, along with previous literature results, span a wide range of orbital period and CV type. In general, dwarf novae in which the secondary star is seen show weak to no CO absorption while polar and pre-CV donor stars appear to have normal CO absorption for their spectral type. However, this is not universal. The presence of normal looking CO absorption in the dwarf nova SS Aur and the hibernating CV QS Vir and a complete lack of CO absorption in the long period polar V1309 Ori cloud the issue. A summary of the literature pointing to non-solar abundances including enhanced NV/CIV ratios is presented. It appears that some CVs have non-solar abundance m...

  19. On the SW Sex-Type Eclipsing Cataclysmic Variable SDSS0756+0858

    CERN Document Server

    Tovmassian, Gagik; Gonzalez-Buitrago, Diego; Zharikov, Sergey; García-Díaz, Maria Teresa

    2014-01-01

    We conducted a spectroscopic and photometric study of SDSS J075653.11+085831. X-ray observations were also attempted. We determined the orbital period of this binary system to be 3.29 hours. It is a deep eclipsing system, whose spectra shows mostly single peaked Balmer emission lines and a quite intense He II line. There is also the presence of faint (often double peaked) He I emission lines as well as several absorption lines; Mg I being the most prominent. All these features point towards affiliation of this object to the growing number of SW Sex-type objects. We developed a phenomenological model of a SW Sex system to reproduce the observed photometric and spectral features.

  20. Interstellar Absorption Lines in the Direction of the Cataclysmic Variable SS Cygni

    CERN Document Server

    Ritchey, Adam M; McKeever, Jean

    2013-01-01

    We present an analysis of interstellar absorption lines in high-resolution optical echelle spectra of SS Cyg obtained during an outburst in 2013 June and in archival Hubble Space Telescope and Far Ultraviolet Spectroscopic Explorer data. The Ca II K and Na I D lines toward SS Cyg are compared with those toward nearby B and A stars in an effort to place constraints on the distance to SS Cyg. We find that the distance constraints are not very robust from this method due to the rather slow increase in neutral gas column density with distance and the scatter in the column densities from one sight line to another. However, the optical absorption-line measurements allow us to derive a precise estimate for the line-of-sight reddening of E(B-V) = 0.020+/-0.005 mag. Furthermore, our analysis of the absorption lines of O I, Si II, P II, and Fe II seen in the UV spectra yields an estimate of the H I column density and depletion strength in this direction.

  1. Synthetic Spectrum Constraints on a Model of the Cataclysmic Variable QU Carinae

    Science.gov (United States)

    2008-01-01

    1 0:015, in agreementwithVerbunt (1987). In x 8 we model the ISM atomic and molecular hydrogen absorption lines and find a hydrogen column density...knowledge of i. GP82 spectrophotometry sets a limit of 1% on the depth of any absorption feature from the secondary star in the QU Car optical...temperature and density of the interstellar absorption lines of atomic andmolecular hydrogen. The ISMmodel assumes that the temperature, bulk velocity

  2. Features of the Matter Flows in the Peculiar Cataclysmic Variable AE Aquarii

    CERN Document Server

    Isakova, P B; Zhilkin, A G; Bisikalo, D V; Beskrovnaya, N G

    2016-01-01

    The structure of plasma flows in close binary systems in which one of the components is a rapidly rotating magnetic white dwarf is studied. The main example considered is the AE Aquarii system; the spin period of the white dwarf is about a factor of 1000 shorter than the orbital period, and the magnetic field on the white dwarf surface is of order of 50 MG. The mass transfer in this system was analyzed via numerical solution of the system of MHD equations. These computations show that the magnetic field of the white dwarf does not significantly influence the velocity field of the material in its Roche lobe in the case of laminar flow regime, so that the field does not hinder the formation of a transient disk (ring) surrounding the magnetosphere. However, the efficiency of the energy and angular momentum exchange between the white dwarf and the surrounding material increases considerably with the development of turbulent motions in the matter, resulting in its acceleration at the magnetospheric boundary and fu...

  3. The space density and X-ray luminosity function of non-magnetic cataclysmic variables

    CERN Document Server

    Pretorius, Magaretha L

    2011-01-01

    We combine two complete, X-ray flux-limited surveys, the ROSAT Bright Survey (RBS) and the ROSAT North Ecliptic Pole (NEP) survey, to measure the space density (\\rho) and X-ray luminosity function (\\Phi) of non-magnetic CVs. The combined survey has a flux limit of F_X \\ga 1.1 \\times 10^{-12} erg cm^{-2}s^{-1} over most of its solid angle of just over 2\\pi, but is as deep as \\simeq 10^{-14} erg cm^{-2}s^{-1} over a small area. The CV sample that we construct from these two surveys contains 20 non-magnetic systems. We carefully include all sources of statistical error in calculating \\rho and \\Phi by using Monte Carlo simulations; the most important uncertainty proves to be the often large errors in distances estimates. If we assume that the 20 CVs in the combined RBS and NEP survey sample are representative of the intrinsic population, the space density of non-magnetic CVs is 4^{+6}_{-2} \\times 10^{-6} pc^{-3}. We discuss the difficulty in measuring \\Phi in some detail---in order to account for biases in the me...

  4. Spitzer Space Telescope observations of magnetic cataclysmic variables: possibilities for the presence of dust in polars

    CERN Document Server

    Brinkworth, C S; Wachter, S; Howell, S B; Ciardi, D R; Szkody, P; Harrison, T E; van Belle, G T; Esin, A A; 10.1086/512797

    2009-01-01

    We present Spitzer Space Telescope photometry of six short-period polars, EF Eri, V347 Pav, VV Pup, V834 Cen, GG Leo, and MR Ser. We have combined the Spitzer Infrared Array Camera (3.6 -8.0 microns) data with the 2MASS J, H, K_s photometry to construct the spectral energy distributions of these systems from the near- to mid-IR (1.235 - 8 microns). We find that five out of the six polars have flux densities in the mid-IR that are substantially in excess of the values expected from the stellar components alone. We have modeled the observed SEDs with a combination of contributions from the white dwarf, secondary star, and either cyclotron emission or a cool, circumbinary dust disk to fill in the long-wavelength excess. We find that a circumbinary dust disk is the most likely cause of the 8 micron excess in all cases, but we have been unable to rule out the specific (but unlikely) case of completely optically thin cyclotron emission as the source of the observed 8 micron flux density. While both model components...

  5. Voracious vortexes in cataclysmic variables. Multi-epoch tomographic study of HT Cassiopeia

    CERN Document Server

    Neustroev, V V; Borisov, N V

    2016-01-01

    We present multi-epoch, time-resolved optical spectroscopic observations of the dwarf nova HT Cas, obtained during 1986, 1992, 1995 and 2005 with the aim to study the properties of emission structures in the system. We determined that the accretion disc radius, measured from the double-peaked emission line profiles, is persistently large and lies within the range of 0.45-0.52a, where a is the binary separation. This is close to the tidal truncation radius r_max=0.52a. This result contradicts with previous radius measurements. An extensive set of Doppler maps has revealed a very complex emission structure of the accretion disc. Apart from a ring of disc emission, the tomograms display at least three areas of enhanced emission: the hot spot from the area of interaction between the gas stream and the disc, which is superposed on the elongated spiral structure, and the extended bright region on the leading side of the disc, opposite to the location of the hot spot. The position of the hot spot in all the emission...

  6. A Study of the X-Ray Emission of Magnetic Cataclysmic Variable Ae Aquarii

    CERN Document Server

    Choi, C S; Agrawal, P C; Choi, Chul-Sung; Dotani, Tadayasu

    1999-01-01

    We report results from analysis of the X-ray observations of AE Aqr, made with Ginga in June 1988 and with ASCA in October 1995. Pulsations are detected clearly with a sinusoidal pulse profile with periods of $33.076\\pm0.001$ s (Ginga) and $33.077\\pm0.003$ s (ASCA)\\@. The pulse amplitude is relatively small and the modulated flux remains nearly constant despite a factor of 3 change in the average flux during the flare. We reproduce the time-averaged spectrum in the 0.4 -- 10 keV energy band by a thermal emission model with a combination of two different temperatures: kT$_1 = 0.68^{+0.01}_{-0.02}$ keV and kT$_2 = 2.9^{+0.3}_{-0.2}$ keV\\@. There is no significant difference between the quiescent and flare energy spectra, although a hint of spectral hardening is recognized during the flare. We interpret these observational results with a model in which AE Aqr is in a propeller stage. Based on this propeller scenario, we suggest that the X-ray emission is originated from magnetospheric radiation.

  7. VizieR Online Data Catalog: Galactic cataclysmic variables distances (Ozdonmez+, 2015)

    Science.gov (United States)

    Ozdonmez, A.; Ak, T.; Bilir, S.

    2015-06-01

    The data sample used in construction of the new PLCs relation consists of CVs in Table 1 including their classes, orbital periods (Porb), trigonometric parallaxes (π) relative parallax errors (σ_π/π), 2MASS J and Ks magnitudes and WISE W1 magnitudes. (1 data file).

  8. Fe Line Diagnostics of Cataclysmic Variables and Galactic Ridge X-ray Emission

    CERN Document Server

    Xu, Xiao-jie; Li, Xiang-Dong

    2016-01-01

    The properties of the Galactic Ridge X-ray Emission (GRXE) observed in the 2-10 keV band place fundamental constraints on various types of X-ray sources in the Milky Way. Although the primarily discrete origin of the emission is now well established, the responsible populations of these sources remain uncertain, especially at relatively low fluxes. To provide insights into this issue, we systematically characterize the Fe emission line properties of the candidate types of the sources in the solar neighborhood and compare them with those measured for the GRXE. Our source sample includes 6 symbiotic stars (SSs), 16 intermediate polars (IPs), 3 polars, 16 quiescent dwarf novae (DNe) and 4 active binaries (ABs). We find that the mean equivalent width ($EW_{6.7}$) of the 6.7-keV line and the mean 7.0/6.7-keV line ratio are $107\\pm16.0$ eV and $0.71\\pm 0.04$ for intermediate polars and $221\\pm 135$ eV and $0.44\\pm 0.14$ for polars, respectively, which are all substantially different from those ($490\\pm15 $~eV and $...

  9. EST Table: BB982110 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB982110 ovS3002A12r 10/09/28 100 %/133 aa ref|NP_001036841.1| Annexin IX isoform A... [Bombyx mori] dbj|BAA92809.1| annexin IX-A [Bombyx mori] 10/08/28 77 %/131 aa FBpp0119685|DanaGF16493-PA 10...ANXB9 10/09/10 65 %/131 aa gnl|Amel|GB16448-PA 10/09/10 76 %/132 aa gi|91092420|ref|XP_967931.1| PREDICTED: similar to Annexin IX CG5730-PC [Tribolium castaneum] NM_001043376 ovS3 ...

  10. EST Table: BB991585 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB991585 E_ET_MSV3_16C05_R_0 10/09/28 100 %/123 aa ref|NP_001106137.1| Annexin IX i...soform C [Bombyx mori] dbj|BAA92811.1| annexin IX-C [Bombyx mori] 10/08/28 71 %/123 aa FBpp0196538|DsecGM150...1|gene:ANXB9 10/09/10 61 %/121 aa gnl|Amel|GB16448-PA 10/09/10 73 %/121 aa gi|91092420|ref|XP_967931.1| PREDICTED: similar to Annexin IX CG5730-PC [Tribolium castaneum] FS780436 MSV3 ...

  11. EST Table: BB983583 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB983583 ovS3022E04r 10/09/28 91 %/192 aa ref|NP_001106136.1| Annexin IX isoform B ...[Bombyx mori] dbj|BAA92810.1| annexin IX-B [Bombyx mori] 10/08/28 75 %/192 aa FBpp0280989|DpseGA19090-PA 10/...NXB9 10/09/10 63 %/192 aa gnl|Amel|GB16448-PA 10/09/10 74 %/192 aa gi|91092420|ref|XP_967931.1| PREDICTED: similar to Annexin IX CG5730-PC [Tribolium castaneum] NM_001043376 ovS3 ...

  12. EST Table: BB988547 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB988547 E_ET_psgV_13E03_F_0 10/09/28 100 %/187 aa ref|NP_001040124.1| exuperantia ...[Bombyx mori] gb|ABD36117.1| exuperantia [Bombyx mori] 10/08/28 53 %/162 aa FBpp0181537|DperGL17430-PA 10/08...aa gnl|Amel|GB19360-PA 10/09/10 59 %/182 aa gi|91085815|ref|XP_974770.1| PREDICTED: similar to exuperantia [Tribolium castaneum] FS919769 PSV3 ...

  13. EST Table: BB989849 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB989849 E_ET_psgV_29E04_F_0 10/09/28 96 %/147 aa ref|NP_731941.1| effete [Drosophi...la melanogaster] ref|NP_001119686.1| effete [Acyrthosiphon pisum] ref|XP_310998.2| AGAP000145-PA [Anopheles ...protein ligase) (Ubiquitin carrier protein) (Protein effete) [Tribolium castaneum...AltName: Full=Ubiquitin-protein ligase; AltName: Full=Ubiquitin carrier protein; AltName: Full=Protein effet...e emb|CAA44453.1| ubiquitin-conjugating enzyme [Drosophila melanogaster] gb|AAF55093.1| effet

  14. EST Table: BB983718 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB983718 ovS3024C07r 10/09/28 47 %/160 aa gb|AAP42818.1| NADH dehydrogenase subunit 6 [Bombyx mandarin...a] gb|ADE18271.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|ADE18284.1| NADH deh...ydrogenase subunit 6 [Bombyx mandarina] gb|ADE18388.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|AD...E18557.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|ADE18583.1| NADH deh...ydrogenase subunit 6 [Bombyx mandarina] gb|ADE18661.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|AD

  15. EST Table: BB983048 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB983048 ovS3015B10r 10/09/28 46 %/157 aa gb|AAP42818.1| NADH dehydrogenase subunit 6 [Bombyx mandarin...a] gb|ADE18271.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|ADE18284.1| NADH deh...ydrogenase subunit 6 [Bombyx mandarina] gb|ADE18388.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|AD...E18557.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|ADE18583.1| NADH deh...ydrogenase subunit 6 [Bombyx mandarina] gb|ADE18661.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|AD

  16. EST Table: BB986576 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB986576 E_ET_MSV3_19D12_F_0 10/09/28 46 %/187 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 34 %/114 aa FBpp0147931|DgriGH14025-PA 10/08/27 n.h 10/09/10 low homology 10/09/10 low homology 10/09/10 n.h FS937505 MSV3 ...

  17. EST Table: BB987373 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987373 E_ET_MSV3_30C12_F_0 10/09/28 39 %/185 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h FS937505 MSV3 ...

  18. EST Table: BB987165 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB987165 E_ET_MSV3_27C09_F_0 10/09/28 36 %/162 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h FS937505 MSV3 ...

  19. EST Table: BB986178 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB986178 E_ET_MSV3_14E04_F_0 10/09/28 38 %/173 aa ref|NP_001129360.1| osiris 9 [Bom...byx mori] gb|ACI23620.1| osiris 9 [Bombyx mori] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h FS937505 MSV3 ...

  20. ATLAS SM VH(bb) Run-2 Search

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00025104; The ATLAS collaboration

    2016-01-01

    The Higgs boson discovered at the LHC in 2012 has been observed coupling directly to W and Z bosons and to tau leptons, and indirectly to top quarks. In order to probe if it is indeed the particle predicted by the Standard Model, direct couplings of the Higgs boson to quarks must also be measured. The Higgs boson decays most often to a pair of bottom quarks (with a branching ratio of 58%). When the Higgs boson is produced alone in gluon-gluon fusion, the signal in this decay mode is overwhelmed by the regular multi-jet background. By requiring the Higgs boson to be produced in association with a vector boson V (W or Z), which is further required to decay leptonically, data events can be selected using charged-lepton or missing transverse energy triggers. The Tevatron experiments presented combined results showing evidence for the VH(H to bb) process at a significance level of about 3 standard deviations, while the combined LHC results from Run II data show a 2.6 standard deviation evidence for the H to bb dec...

  1. Cloning and expression of recombinant human platelet-derived growth factor-BB in Pichia Pink.

    Science.gov (United States)

    Babavalian, H; Latifi, A M; Shokrgozar, M A; Bonakdar, S; Tebyanian, H; Shakeri, F

    2016-07-31

    The PDGF-BB plays a key role in several pathogenesis diseases and it is believed to be an important mediator for wound healing. The recombinant human PDGF-BB is safe and effective to stimulate the healing of chronic, full thickness and lower extremity diabetic neurotrophic ulcers. In the present study, we attempted to produce a PDGF-BB growth factor and also, evaluate its functionality in cell proliferation in yeast host Pichia pink. Pichia pink yeast was used as a host for evaluation of the rhPDGF-BB expression. The coding sequence of PDGF-BB protein was synthesized after optimization and packed into the pGEM. Recombinant proteins were produced and purified. The construct of pPinkα-HC-pdgf was confirmed by sequence, the PDGF-BB protein was expressed and purified with using a nickel affinity chromatography column and then characterized by SDS-PAGE electrophoresis. The biological activity of PDGF-BB was estimated with using human fibroblast cell line. The measurement of protein concentration was determined by Bradford and human PDGF-BB ELISA kit. Purified rhPDGF-BB showed similar biological activity (as the standard PDGF-BB) and suggested that the recombinant protein has a successful protein expression (as well as considerable biological activity in P. pink host). The exact amount of recombinant PDGF-BB concentrations were measured by specific ELISA test which it was about 30 μg/ml. Our study suggested that efficiency of biological activity of PDGF-BB protein may be related to its conformational similarity with standard type and also, it practically may be important in wound healing and tissue regeneration.

  2. The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12®

    Directory of Open Access Journals (Sweden)

    Mikkel Jungersen

    2014-03-01

    Full Text Available This review presents selected data on the probiotic strain Bifidobacterium animalis subsp. lactis BB-12® (BB-12®, which is the world’s most documented probiotic Bifidobacterium. It is described in more than 300 scientific publications out of which more than 130 are publications of human clinical studies. The complete genome sequence of BB-12® has been determined and published. BB-12® originates from Chr. Hansen’s collection of dairy cultures and has high stability in foods and as freeze dried powders. Strain characteristics and mechanisms of BB-12® have been established through extensive in vitro testing. BB-12® exhibits excellent gastric acid and bile tolerance; it contains bile salt hydrolase, and has strong mucus adherence properties, all valuable probiotic characteristics. Pathogen inhibition, barrier function enhancement, and immune interactions are mechanisms that all have been demonstrated for BB-12®. BB-12® has proven its beneficial health effect in numerous clinical studies within gastrointestinal health and immune function. Clinical studies have demonstrated survival of BB-12® through the gastrointestinal tract and BB-12® has been shown to support a healthy gastrointestinal microbiota. Furthermore, BB-12® has been shown to improve bowel function, to have a protective effect against diarrhea, and to reduce side effects of antibiotic treatment, such as antibiotic-associated diarrhea. In terms of immune function, clinical studies have shown that BB-12® increases the body’s resistance to common respiratory infections as well as reduces the incidence of acute respiratory tract infections.

  3. Reconstructing Glacial Lake Vitim and its cataclysmic drainage to the Arctic Ocean

    Science.gov (United States)

    Margold, Martin; Jansen, John D.; Gurinov, Artem L.; Codilean, Alexandru T.; Preusser, Frank

    2013-04-01

    A large glacial lake (23500 km2/3000 km3) was formed when the River Vitim, one of the largest tributaries of the Lena River in Siberia, Russia, was blocked by glaciers from the Kodar Mountains. This lake, Glacial Lake Vitim, was subsequently drained in a large outburst flood that followed the rivers Vitim and Lena to the Arctic Ocean. Evidence of a cataclysmic drainage was first identified in the form of a large bedrock canyon in the area of the postulated ice dam. The enormous dimensions of this feature (6 x 2 x 0.3 km) suggest formation via a drainage event of extreme magnitude, and field inspection downstream revealed giant bars >100 m above the valley floor, similar to those described from cataclysmic floods elsewhere. We present chronological constraints for the duration of the ice dam and for the timing of the flood based on terrestrial cosmogenic nuclides and optically stimulated luminescence. Given that the volume of Glacial Lake Vitim was significantly larger than other well known lakes associated with cataclysmic outbursts-glacial lakes Missoula (northwestern USA) and Chuja-Kuray (Altai Mountains, Russia)-it is pertinent to assess the possible climatic consequences of Lake Vitim's drainage. The outburst flood from Glacial Lake Vitim is likely among the largest floods documented on Earth thus far. Possible impacts include rapid change of climate and precipitation patterns in the area of the former glacial lake, major disturbance along the flood course to the Arctic, and perhaps even regional-scale climatic feedbacks linked to altered sea ice dynamics in the Arctic Ocean.

  4. Molecular characterization of a new Babesia bovis thrombospondin-related anonymous protein (BbTRAP2.

    Directory of Open Access Journals (Sweden)

    Mohamad Alaa Terkawi

    Full Text Available A gene encoding a Babesia bovis protein that shares significant degree of similarity to other apicomplexan thrombospondin-related anonymous proteins (TRAPs was found in the genomic database and designated as BbTRAP2. Recombinant protein containing a conserved region of BbTRAP2 was produced in E. coli. A high antigenicity of recombinant BbTRAP2 (rBbTRAP2 was observed with field B. bovis-infected bovine sera collected from geographically different regions of the world. Moreover, antiserum against rBbTRAP2 specifically reacted with the authentic protein by Western blot analysis and an indirect fluorescent antibody test. Three bands corresponding to 104-, 76-, and 44-kDa proteins were identified in the parasite lysates and two bands of 76- and 44-kDa proteins were detected in the supernatant of cultivated parasites, indicating that BbTRAP2 was proteolytically processed and shed into the culture. Apical and surface localizations of BbTRAP2 were observed in the intracellular and extracellular parasites, respectively, by confocal laser microscopic examination. Moreover, native BbTRAP2 was precipitated by bovine erythrocytes, suggesting its role in the attachment to erythrocytes. Furthermore, the specific antibody to rBbTRAP2 inhibited the growth of B. bovis in a concentration-dependent manner. Consistently, pre-incubation of the free merozoites with the antibody to rBbTRAP2 resulted in an inhibition of the parasite invasion into host erythrocytes. Interestingly, the antibody to rBbTRAP2 was the most inhibitive for the parasite's growth as compared to those of a set of antisera produced against different recombinant proteins, including merozoite surface antigen 2c (BbMSA-2c, rhoptry-associated protein 1 C-terminal (BbRAP-1CT, and spherical body protein 1 (BbSBP-1. These results suggest that BbTRAP2 might be a potential candidate for development of a subunit vaccine against B. bovis infection.

  5. The newly discovered eclipsing cataclysmic star 2MASS J16211735 + 4412541 and its peculiarity

    Science.gov (United States)

    Kjurkchieva, Diana P.; Popov, Velimir A.; Vasileva, Doroteya L.; Petrov, Nikola I.

    2017-04-01

    We present our observations of the newly discovered, eclipsing cataclysmic star 2MASS J16211735 + 4412541 carried out two weeks after its outburst at the beginning of June 2016. Its main peculiarity is the big increasing of eclipse depth during outburst. We qualitatively modelled the folded light curves at quiescence and outburst in order to explain the reason for increase of the primary luminosity about two hundred times. The light curve fits revealed that such an effect can be reproduced by a flat disc whose radius and temperature are several times bigger than those of the primary at quiescence.

  6. Boosted H­->bb Tagger In Run II

    CERN Document Server

    Sahinsoy, Merve; The ATLAS collaboration

    2016-01-01

    Several searches for Higgs bosons decaying to b­quark pairs benefit from the increased Run II centre­of­mass energy by exploiting the large transvers­momentum (boosted) Higgs boson regime, where the two b­jets are merged into one large­radius jet. ATLAS uses a boosted H­>bb tagger algorithm to separate the Higgs signal from the background processes (QCD, W and Z bosons, top quarks). The tagger takes as input a large­R=1.0 jet calibrating the pseudorapidity, energy and mass scale. The tagger employs b­tagging, Higgs candidate mass, and substructure information. The performance of several operating points in Higgs boson signal and QCD and ttbar all­hadronic backgrounds are presented. Systematic uncertainties are evaluated so that this tagger can be used in analyses.

  7. Search for the H->bb decay in LHCb

    CERN Document Server

    Vieites Díaz, María

    2014-01-01

    The recent discovery of a Higgs-like boson by ATLAS and CMS has drawn the general attention to this topic, promoting the development of tools needed for the study of this new particle. The mass of this boson has been found to be close to 125 GeV=c2, what, as shown in Figure 1, enhances the H ! bb mode over the other possible decays of this particle. Since the mass of the Higgs boson has to be reconstructed from two jets, this mode is particularly challenging in LHCb due to its limited acceptance (when compared with ATLAS or CMS). However, jet b-tagging is expected to be easier due to the highly specic design for b-physics of the detector.

  8. EST Table: BB986940 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available ina] gb|ADE18271.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|ADE18284.1| ...NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|ADE18388.1| NADH dehydrogenase subunit 6 [Bombyx mandarin...a] gb|ADE18557.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|ADE18583.1| ...NADH dehydrogenase subunit 6 [Bombyx mandarina] gb|ADE18661.1| NADH dehydrogenase subunit 6 [Bombyx mandarin...a] gb|ADE18713.1| NADH dehydrogenase subunit 6 [Bombyx mandarina] 10/08/28 n.h 10/08/27 n.h 10/09/10 n.h 10/09/10 n.h 10/09/10 n.h BB990129 MSV3 ...

  9. InterProScan Result: BB992474 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB992474 BB992474_6_ORF1 61D89618F637E5E4 PANTHER PTHR11956 ARGINYL-TRNA SYNTHETASE... 1.5e-69 T IPR001278 Arginyl-tRNA synthetase, class Ic Molecular Function: arginine-tRNA ligase activity (GO

  10. InterProScan Result: BB983131 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB983131 BB983131_6_ORF1 48B96D5663B2802B PANTHER PTHR11538 PHENYLALANYL-TRNA SYNTHETAS...E 8.1e-59 T IPR002319 Phenylalanyl-tRNA synthetase Molecular Function: tRNA binding (GO:0000049)|Molecul

  11. InterProScan Result: BB988450 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB988450 BB988450_1_ORF2 3834FAB5D3F21F02 PFAM PF00420 Oxidored_q2 7e-10 T IPR00113...3 NADH:ubiquinone/quinone oxidoreductase, chain 4L Biological Process: ATP synthesis coupled electron transport (GO:0042773)|Biological Process: oxidation reduction (GO:0055114) ...

  12. InterProScan Result: BB983158 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB983158 BB983158_6_ORF1 C72FC0480F5782A7 PFAM PF00175 NAD_binding_1 9e-16 T IPR001433 Oxido...reductase FAD/NAD(P)-binding Molecular Function: oxidoreductase activity (GO:0016491)|Biological Process: oxidation reduction (GO:0055114) ...

  13. InterProScan Result: BB988450 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB988450 BB988450_3_ORF3 334E71F0E13380BF PFAM PF00361 Oxidored_q1 6e-08 T IPR00175...0 NADH:ubiquinone/plastoquinone oxidoreductase Molecular Function: NADH dehydrogenase (ubiquinone) activity

  14. InterProScan Result: BB988450 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB988450 BB988450_3_ORF2 68BA312451F1493A PFAM PF01059 Oxidored_q5_N 2.7e-05 T IPR000260 NADH:ubiquinone oxi...doreductase, chain 4, N-terminal Cellular Component: mitochondrion (GO:0005739)|Mol

  15. InterProScan Result: BB990129 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB990129 BB990129_2_ORF3 6DA886178EF7B933 PFAM PF00499 Oxidored_q3 4.9e-09 T IPR001...457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 Molecular Function: NADH dehydrogenase (ubiquinone

  16. InterProScan Result: BB989196 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB989196 BB989196_1_ORF1 A29F72E9B3E967D2 PANTHER PTHR23355 RIBONUCLEASE 6.5e-130 T... IPR001900 unintegrated Molecular Function: RNA binding (GO:0003723)|Molecular Function: ribonuclease activity (GO:0004540) ...

  17. InterProScan Result: BB989196 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB989196 BB989196_1_ORF1 A29F72E9B3E967D2 PROSITE PS01175 RIBONUCLEASE_II NA T IPR001900 Ribonu...clease II/R Molecular Function: RNA binding (GO:0003723)|Molecular Function: ribonuclease activity (GO:0004540) ...

  18. InterProScan Result: BB989196 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB989196 BB989196_1_ORF1 A29F72E9B3E967D2 PROSITE PS01175 RIBONUCLEASE_II NA ? IPR0...01900 unintegrated Molecular Function: RNA binding (GO:0003723)|Molecular Function: ribonuclease activity (GO:0004540) ...

  19. 76 FR 13615 - B&B Manufacturing Site; Mobile, Mobile County, AL; Notice of Settlement

    Science.gov (United States)

    2011-03-14

    ... AGENCY B&B Manufacturing Site; Mobile, Mobile County, AL; Notice of Settlement AGENCY: Environmental... Manufacturing Site located in Mobile, Mobile County, Alabama for publication. DATES: The Agency will consider... No. EPA-RO4- SFUND-2011-0192 or Site name B&B Manufacturing Superfund Site by one of the...

  20. InterProScan Result: BB990769 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB990769 BB990769_4_ORF1 379E9C2427B1CC10 SUPERFAMILY SSF103473 MFS general substra...te transporter 1.2e-11 T IPR016196 Major facilitator superfamily, general substrate transporter ...

  1. InterProScan Result: BB990255 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB990255 BB990255_2_ORF1 E87DF8DAB3DB2BBF SUPERFAMILY SSF103473 MFS general substra...te transporter 7e-11 T IPR016196 Major facilitator superfamily, general substrate transporter ...

  2. InterProScan Result: BB990958 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB990958 BB990958_6_ORF1 C5508D74FF93B1B9 PANTHER PTHR11783:SF3 FLAVONOL SULFOTRANS...FERASE-LIKE 9.5e-72 T IPR000863 unintegrated Molecular Function: sulfotransferase activity (GO:0008146) ...

  3. InterProScan Result: BB990958 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB990958 BB990958_6_ORF1 C5508D74FF93B1B9 PANTHER PTHR11783 SULFOTRANSFERASE (SULT)... 9.5e-72 T IPR000863 unintegrated Molecular Function: sulfotransferase activity (GO:0008146) ...

  4. InterProScan Result: BB993418 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB993418 BB993418_6_ORF2 7325F21342D1E3DD PANTHER PTHR12479:SF4 LYSOSOMAL-ASSOCIATED TRANSME...MBRANE PROTEIN 1.9e-69 T IPR018400 Lysosomal-associated transmembrane protein, CG14767-PB ...

  5. InterProScan Result: BB993418 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB993418 BB993418_6_ORF2 7325F21342D1E3DD PANTHER PTHR12479 LYSOSOMAL-ASSOCIATED TRANSME...MBRANE PROTEIN 1.9e-69 T IPR004687 Golgi 4-transmembrane spanning transporter Biological Process: transport (GO:0006810)|Cellular Component: integral to membrane (GO:0016021) ...

  6. InterProScan Result: BB992083 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB992083 BB992083_1_ORF1 81A6A835284D525E PANTHER PTHR11875:SF7 NUCLEOSOME ASSEMBLY... PROTEIN 1 NA ? IPR002164 unintegrated Cellular Component: nucleus (GO:0005634)|Biological Process: nucleosome assembly (GO:0006334) ...

  7. InterProScan Result: BB992083 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BB992083 BB992083_1_ORF1 81A6A835284D525E PANTHER PTHR11875:SF7 NUCLEOSOME ASSEMBLY... PROTEIN 1 1.4e-68 T IPR002164 unintegrated Cellular Component: nucleus (GO:0005634)|Biological Process: nucleosome assembly (GO:0006334) ...

  8. All hadronic ttH(bb) trigger study and analysis using the BDT method

    CERN Document Server

    Foti, Maria Giovanna

    2015-01-01

    The aim of this report is to describe the project on which I have worked as a CERN Summer Student 2015. The project consists of two parts: 1. Study of the trigger efficiencies for all hadronic ttH(bb) analysis; 2. All hadronic ttH(bb) analysis using the BDT (and Fisher) methods.

  9. Controlled delivery of platelet-derived growth factor-BB from injectable microsphere/hydrogel composites.

    Science.gov (United States)

    Wu, Hua; Liu, Jiaoyan; Wu, Jingjing; Wan, Ying; Chen, Yun

    2016-12-01

    Platelet-derived growth factor-BB (PGDF-BB) loaded gelatin microspheres with an average size of about 2μm was incorporated into chitosan/silk fibroin/glycerophosphate (GP) solutions to prepare composites. The formulated composite solutions were able to form into hydrogels in a temperature range between 32 and 37°C at a pH of ca.7. They had good fluidity at 25°C and showed shear-thinning features at both 25 and 37°C, revealing that they are injectable at room temperature. Elastic modulus of some composites at 37°C was about 10-fold higher than that of chitosan/GP gel, confirming that these composites behave like mechanically strong gels. Optimal composites showed abilities to administrate PDGF-BB release in an approximately linear manner up to 5 weeks. The PDGF-BB release could be regulated by the PDGF-BB load and the silk fibroin content in the composites in an individual or cooperative way. In vivo degradation of composites demonstrated that some of them had markedly enhanced degradation endurance as compared to the chitosan/GP gel. PDGF-BB-stimulated DNA synthesis in Balb/c 3T3 fibroblasts and PDGF-BB-induced cell migration suggested that the bioactivity of released PDGF-BB was well retained.

  10. Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt.

    Science.gov (United States)

    Cartel, Nicholas J; Wang, Jinxia; Post, Martin

    2002-04-01

    Previously we have demonstrated that the phosphoinositide 3-kinase (PI-3K) signal-transduction pathway mediates platelet-derived growth factor (PDGF)-BB-induced glycosaminoglycan (GAG) synthesis in fetal lung fibroblasts. In the present study we further investigated the signal-transduction pathway(s) that results in PDGF-BB-induced GAG synthesis. Over-expression of a soluble PDGF beta-receptor as well as a mutated form of the beta-receptor, unable to bind PI-3K, diminished GAG synthesis in fetal lung fibroblasts subsequent to PDGF-BB stimulation. The PI-3K inhibitor wortmannin blocked PDGF-BB-induced Akt activity as well as significantly diminishing PDGF-BB-mediated GAG synthesis. Expression of dominant-negative PI-3K also abrogated Akt activity and GAG synthesis. Furthermore, expression of dominant-negative Akt abrogated endogenous Akt activity, Rab3D phosphorylation and GAG synthesis, whereas expression of constitutively activated Akt stimulated Rab3D phosphorylation and GAG synthesis in the absence of PDGF-BB. Over-expression of wild-type PTEN (phosphatase and tensin homologue deleted in chromosome 10) inhibited Akt activity and concomitantly attenuated GAG synthesis in fibroblasts stimulated with PDGF-BB. These data suggest that Akt is an integral protein involved in PDGF-BB-mediated GAG regulation in fetal lung fibroblasts.

  11. Insights into physiological traits of Bifidobacterium animalis subsp. lactis BB-12 through membrane proteome analysis

    DEFF Research Database (Denmark)

    Gilad, Ofir; Hjernø, Karin; Østerlund, Eva Christina

    2012-01-01

    Bifidobacterium animalis subsp. lactis BB-12 is a widely used probiotic strain associated with a variety of health-promoting traits. There is, however, only limited knowledge available regarding the membrane proteome and the proteins involved in oligosaccharide transport in BB-12. We applied two...

  12. Genetic heterogenicity in the major histocompatibility complex of various BB rat sublines

    DEFF Research Database (Denmark)

    Sørensen, Ilona Kryspin; Dyrberg, T.; Kastern, W.

    1986-01-01

    Fragments of cloned rat class I transplantation antigen genes were used to define the polymorphism detected between two lines of closely related BB rats. One line, BB-Hagedorn (BB/H), is prone to diabetes, and the other (BB control) is resistant. A cDNA probe representing part of the second...... extracellular domain of a class I antigen detected several DNA fragments and revealed a 2kb fragment present in resistant, but absent in diabetes-prone, BB/H rat DNA following digestion with BamH1. A 40 by cDNA probe from the same domain showed a further simplified pattern in the DNA hybridization analysis...... offspring of F1 hybrid parents following cross-breeding between the resistant (BB-control) and diabetes-prone (BB/H) line demonstrate that the class I polymorphism was not linked directly to diabetes. Examination of various other BB lines and sublines indicate that these polymorphisms can be traced back...

  13. Erratum: PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis

    DEFF Research Database (Denmark)

    Cao, R.H.; Bjorndahl, M.A.; Religa, P.;

    2006-01-01

    This corrects the article "PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis", Cancer Cell, 2004, vol. 6(4), pg 333-45.......This corrects the article "PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis", Cancer Cell, 2004, vol. 6(4), pg 333-45....

  14. MT BB: Tomato cultivar for practical classes of plant genetics and breeding

    Directory of Open Access Journals (Sweden)

    Fernando Angelo Piotto

    2013-01-01

    Full Text Available MT BB cultivar originated from a backcross program which aimed at adding two recessive mutations that alter leaf architecture(potato leaf – c and flower color (white flower – wf to Micro-Tom cultivar, which is a tomato miniature. MT BB was developedfor use in practical classes of genetics and breeding in both undergraduate and graduate courses.

  15. Cataclysm No More: New Views on the Timing and Delivery of Lunar Impactors

    Science.gov (United States)

    Zellner, Nicolle E. B.

    2017-09-01

    If properly interpreted, the impact record of the Moon, Earth's nearest neighbour, can be used to gain insights into how the Earth has been influenced by impacting events since its formation 4.5 billion years (Ga) ago. However, the nature and timing of the lunar impactors - and indeed the lunar impact record itself - are not well understood. Of particular interest are the ages of lunar impact basins and what they tell us about the proposed "lunar cataclysm" and/or the late heavy bombardment (LHB), and how this impact episode may have affected early life on Earth or other planets. Investigations of the lunar impactor population over time have been undertaken and include analyses of orbital data and images; lunar, terrestrial, and other planetary sample data; and dynamical modelling. Here, the existing information regarding the nature of the lunar impact record is reviewed and new interpretations are presented. Importantly, it is demonstrated that most evidence supports a prolonged lunar (and thus, terrestrial) bombardment from 4.2 to 3.4 Ga and not a cataclysmic spike at 3.9 Ga. Implications for the conditions required for the origin of life are addressed.

  16. Expression of Cry3Bb1 in transgenic corn MON88017.

    Science.gov (United States)

    Nguyen, Hang Thu; Jehle, Johannes A

    2009-11-11

    To evaluate the effects of transgenic expression of Coleopteran-specific Bt protein Cry3Bb1 on target and nontarget insects in fields with Bt crops, it is necessary to quantify the Cry3Bb1 contents in the plants. Here, we describe the optimization and validation of the quantitative detection of Cry3Bb1 by adapting the commercially available qualitative PathoScreen double antibody sandwich-enzyme-linked immunosorbent assay (DAS-ELISA) for quantitative measurements. The optimized method had an average accuracy of 84-109% and was used to quantify the Cry3Bb1 contents of different tissues of Bt corn MON88017 at four developmental stages during three years (2005-2007) in a field trial in Germany. The Cry3Bb1 contents were determined based on both dry weight and fresh weight. Cry3Bb1 expression was highest in young leaves (228.4 microg/g dw and 35.5 microg/g fw) and lowest in pollen (3.8 microg/g fw). In root tissues, the Cry3Bb1 content declined during the growing season from 130 to 40 microg/g dw. A significant decline of Cry3Bb1 contents was also observed during the growing season in other plant tissues. The Cry3Bb1 contents of different plant tissues strongly correlated to each other. On the basis of the total corn biomass produced on 1 hectare, it was estimated that up to 905 g of Cry3Bb1 is produced per hectare Bt corn MON88017.

  17. BB interactions with static bottom quarks from Lattice QCD

    CERN Document Server

    Bicudo, Pedro; Peters, Antje; Wagner, Marc

    2015-01-01

    The isospin, spin and parity dependent potential of a pair of $B$ mesons is computed using Wilson twisted mass lattice QCD with two flavours of degenerate dynamical quarks. The $B$ meson is addressed in the static-light approximation, i.e.\\ the $b$ quarks are infinitely heavy. From the results of the $B\\,B$ meson-meson potentials, a simple rule can be deduced stating which isospin, spin and parity combinations correspond to attractive and which to repulsive forces. We provide fits to the ground state potentials in the attractive channels and discuss the potentials in the repulsive and excited channels. The attractive channels are most important since they can possibly lead to a bound four-quark state, i.e.\\ a $\\bar{b}\\bar{b}ud$ tetraquark. Using these attractive potentials in the Schr\\"odinger equation, we find indication for such a tetraquark state of two static bottom antiquarks and two light $u/d$ quarks with mass extrapolated down to the physical value.

  18. The TT, TB, EB and BB correlations in anisotropic inflation

    CERN Document Server

    Chen, Xingang; Firouzjahi, Hassan; Wang, Yi

    2014-01-01

    Recently the BICEP2 experiment has detected the B-mode in the CMB polarization map. The ongoing and future experiments will measure the B-mode from different sky coverage and frequency bands, with the potential to reveal non-trivial features in polarization map. In this work we study the TT, TB, EB and BB correlations associated with the B-mode polarization of CMB map in models of charged anisotropic inflation. The model contains a complex inflaton field which is charged under the $U(1)$ gauge. We calculate the statistical anisotropies generated in the power spectra of the curvature perturbation, the tensor perturbation and their cross-correlation. It is shown that the asymmetry in tensor power spectrum is a very sensitive probe of the gauge coupling. While the level of statistical anisotropy in temperature power spectrum can be small and satisfy the observational bounds, the interactions from the gauge coupling can induce large directional dependence in tensor modes. This will leave interesting anisotropic f...

  19. Bifidobacterium animalis subsp. lactis BB-12 in reducing the risk of infections in infancy.

    Science.gov (United States)

    Taipale, Teemu; Pienihäkkinen, Kaisu; Isolauri, Erika; Larsen, Charlotte; Brockmann, Elke; Alanen, Pentti; Jokela, Jorma; Söderling, Eva

    2011-02-01

    The impact of controlled administration of Bifidobacterium animalis subsp. lactis BB-12 (BB-12) on the risk of acute infectious diseases was studied in healthy newborn infants. In this double-blind, placebo-controlled study, 109 newborn 1-month-old infants were assigned randomly to a probiotic group receiving a BB-12-containing tablet (n 55) or to a control group receiving a control tablet (n 54). Test tablets were administered to the infants twice a day (daily dose of BB-12 10 billion colony-forming units) from the age of 1-2 months to 8 months with a novel slow-release pacifier or a spoon. Breastfeeding habits, pacifier use, dietary habits, medications and all signs and symptoms of acute infections were registered. At the age of 8 months, faecal samples were collected for BB-12 determination (quantitative PCR method). The baseline characteristics of the two groups were similar, as was the duration of exclusive breastfeeding. BB-12 was recovered (detection limit log 5) in the faeces of 62% of the infants receiving the BB-12 tablet. The daily duration of pacifier sucking was not associated with the occurrence of acute otitis media. No significant differences between the groups were observed in reported gastrointestinal symptoms, otitis media or use of antibiotics. However, the infants receiving BB-12 were reported to have experienced fewer respiratory infections (65 v. 94%; risk ratio 0·69; 95% CI 0·53, 0·89; P = 0·014) than the control infants. Controlled administration of BB-12 in early childhood may reduce respiratory infections.

  20. Restriction fragment polymorphisms in the major histocompatibility complex of diabetic BB rats

    DEFF Research Database (Denmark)

    Kastern, W.; Dyrberg, T.; Scholler, J.;

    1984-01-01

    HI fragment was present in all the nondiabetic rats examined, but absent in the diabetic rats. Similar polymorphisms were observed with various other restriction enzymes, particularly XbaI, HindII, and SacI. There were no polymorphisms detected using either a human DR-alpha (class II antigen heavy chain......DNA isolated from diabetic BB (BB/Hagedorn) rats was examined for restriction fragment length differences within the major histocompatibility complex (MHC) as compared with nondiabetic (W-subline) BB rats. Polymorphisms were detected using a mouse class I MHC gene as probe. Specifically, a 2-kb Bam...

  1. Catalogue of cataclysmic binaries, low-mass X-ray binaries and related objects (Seventh edition)

    CERN Document Server

    Ritter, H

    2003-01-01

    The catalogue lists coordinates, apparent magnitudes, orbital parameters, and stellar parameters of the components and other characteristc properties of 472 cataclysmic binaries, 71 low-mass X-ray binaries and 113 related objects with known or suspected orbital periods together with a comprehensive selection of the relevant recent literature. In addition the catalogue contains a list of references to published finding charts for 635 of the 656 objects, and a cross-reference list of alias object designations. Literature published before 1 January 2003 has, as far as possible, been taken into account. All data can be accessed via the dedicated catalogue webpage at http://www.mpa-garching.mpg.de/RKcat/ (MPA) and http://physics.open.ac.uk/RKcat/ (OU). We will update the information given on the catalogue webpage regularly, initially every six months.

  2. Variable Star Network: World Center for Transient Object Astronomy and Variable Stars

    Science.gov (United States)

    Kato, Taichi; Uemura, Makoto; Ishioka, Ryoko; Nogami, Daisaku; Kunjaya, Chatief; Baba, Hajime; Yamaoka, Hitoshi

    2004-03-01

    Variable Star Network (VSNET) is a global professional-amateur network of researchers in variable stars and related objects, particularly in transient objects, such as cataclysmic variables, black-hole binaries, supernovae, and gamma-ray bursts. The VSNET has been playing a pioneering role in establishing the field of transient object astronomy, by effectively incorporating modern advances in observational astronomy and global electronic networks, as well as collaborative progress in theoretical astronomy and astronomical computing. The VSNET is now one of the best-featured global networks in this field of astronomy. We review the historical progress, design concept, associated technology, and a wealth of scientific achievements powered by VSNET.

  3. Measurement of the ratio of branching fractions ${\\cal B}(B^0 \\to K^{\\ast 0} \\gamma)/{\\cal B}(B^0_s \\to \\phi \\gamma)$

    CERN Document Server

    Aaij, R; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Alkhazov, G; Alvarez Cartelle, P; Alves Jr, A A; Amato, S; Amhis, Y; Anderson, J; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Arrabito, L; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Bachmann, S; Back, J J; Bailey, D S; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bates, A; Bauer, C; Bauer, Th; Bay, A; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Benayoun, M; Bencivenni, G; Benson, S; Benton, J; Bernet, R; Bettler, M -O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blanks, C; Blouw, J; Blusk, S; Bobrov, A; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Büchler-Germann, A; Burducea, I; Bursche, A; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carson, L; Carvalho Akiba, K; Casse, G; Cattaneo, M; Cauet, Ch; Charles, M; Charpentier, Ph; Chiapolini, N; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Collins, P; Comerma-Montells, A; Constantin, F; Contu, A; Cook, A; Coombes, M; Corti, G; Couturier, B; Cowan, G A; Currie, R; D'Ambrosio, C; David, P; David, P N Y; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Lorenzi, F; De Miranda, J M; De Paula, L; De Simone, P; Decamp, D; Deckenhoff, M; Degaudenzi, H; Del Buono, L; Deplano, C; Derkach, D; Deschamps, O; Dettori, F; Dickens, J; Dijkstra, H; Diniz Batista, P; Domingo Bonal, F; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Dzhelyadin, R; Dziurda, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisele, F; Eisenhardt, S; Ekelhof, R; Eklund, L; Elsasser, Ch; Elsby, D; Esperante Pereira, D; Falabella, A; Fanchini, E; Färber, C; Fardell, G; Farinelli, C; Farry, S; Fave, V; Fernandez Albor, V; Ferro-Luzzi, M; Filippov, S; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furcas, S; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garnier, J-C; Garofoli, J; Garra Tico, J; Garrido, L; Gascon, D; Gaspar, C; Gauld, R; Gauvin, N; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hampson, T; Hansmann-Menzemer, S; Harji, R; Harnew, N; Harrison, J; Harrison, P F; Hartmann, T; He, J; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicks, E; Holubyev, K; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Huston, R S; Hutchcroft, D; Hynds, D; Iakovenko, V; Ilten, P; Imong, J; Jacobsson, R; Jaeger, A; Jahjah Hussein, M; Jans, E; Jansen, F; Jaton, P; Jean-Marie, B; Jing, F; John, M; Johnson, D; Jones, C R; Jost, B; Kaballo, M; Kandybei, S; Karacson, M; Karbach, T M; Keaveney, J; Kenyon, I R; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kim, Y M; Knecht, M; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kruzelecki, K; Kucharczyk, M; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J -P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Li, L; Li Gioi, L; Lieng, M; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; von Loeben, J; Lopes, J H; Lopez Asamar, E; Lopez-March, N; Lu, H; Luisier, J; Mac Raighne, A; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Magnin, J; Malde, S; Mamunur, R M D; Manca, G; Mancinelli, G; Mangiafave, N; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martin, L; Martín Sánchez, A; Martinez Santos, D; Massafferri, A; Mathe, Z; Matteuzzi, C; Matveev, M; Maurice, E; Maynard, B; Mazurov, A; McGregor, G; McNulty, R; Meissner, M; Merk, M; Merkel, J; Messi, R; Miglioranzi, S; Milanes, D A; Minard, M -N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Musy, M; Mylroie-Smith, J; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Nedos, M; Needham, M; Neufeld, N; Nguyen, A D; Nguyen-Mau, C; Nicol, M; Niess, V; Nikitin, N; Nikodem, T; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Pal, B K; Palacios, J; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Paterson, S K; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perego, D L; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pessina, G; Petrella, A; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pie Valls, B; Pietrzyk, B; Pilař, T; Pinci, D; Plackett, R; Playfer, S; Plo Casasus, M; Polok, G; Poluektov, A; Polycarpo, E; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pugatch, V; Puig Navarro, A; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Roa Romero, D A; Robbe, P; Rodrigues, E; Rodrigues, F; Rodriguez Perez, P; Rogers, G J; Roiser, S; Romanovsky, V; Rosello, M; Rouvinet, J; Ruf, T; Ruiz, H; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salzmann, C; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santinelli, R; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schleich, S; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M -H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Skwarnicki, T; Smith, N A; Smith, E; Sobczak, K; Soler, F J P; Solomin, A; Soomro, F; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Swientek, S; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tsaregorodtsev, A; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urquijo, P; Uwer, U; Vagnoni, V; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; Velthuis, J J; Veltri, M; Viaud, B; Videau, I; Vieira, D; Vilasis-Cardona, X; Visniakov, J; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Voss, H; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wishahi, J; Witek, M; Witzeling, W; Wotton, S A; Wyllie, K; Xie, Y; Xing, F; Xing, Z; Yang, Z; Young, R; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhong, L; Zvyagin, A

    2012-01-01

    The ratio of branching fractions of the radiative $B$ decays $B^0\\to K^{*0}\\gamma$ and $B^0_s\\to \\phi\\gamma$ has been measured using $0.37\\,$fb$^{-1}$ of $pp$ collisions at a centre of mass energy of $\\sqrt{s}=7\\,$TeV, collected by the LHCb experiment. The value obtained is \\begin{equation} \\frac{{\\cal B}(B^0\\to K^{*0}\\gamma)}{{\\cal B}(B^0_s\\to \\phi\\gamma)} = 1.12 \\pm 0.08^{+0.06}_{-0.04}\\phantom{.}^{+0.09}_{-0.08},\

  4. Reducing toxicity of 4–1BB costimulation: targeting 4–1BB ligands to the tumor stroma with bi-specific aptamer conjugates

    Science.gov (United States)

    Schrand, B; Berezhnoy, A; Brenneman, R; Williams, A; Levay, A; Gilboa, E

    2015-01-01

    Systemic administration of immune modulatory antibodies to cancer patients is associated with autoimmune pathologies. We have developed a clinically feasible and broadly applicable approach to limit immune stimulation to disseminated tumor lesions using a bi-specific agonistic 4–1BB oligonucleotide aptamer targeted to a broadly expressed stromal product (e.g., VEGF or osteopontin). The stroma-targeted aptamer conjugates engendered potent antitumor immunity against unrelated tumors and exhibited a superior therapeutic index compared to non-targeted agonistic 4–1BB antibody. PMID:25949891

  5. Converter station Timelkam. A new OeBB traction energy supply installation; Umrichterwerk Timelkam. Eine neue Bahnstromversorgungsanlage der OeBB

    Energy Technology Data Exchange (ETDEWEB)

    Baldauf, Hugo [OeBB-Infrastruktur AG, Innsbruck (Austria). Geschaeftsbereich Kraftwerke

    2010-07-15

    As a consequence of upgrading the western main line the traction energy demand increased within the Oberoesterreich region. Therefore, a new feeding point into the OeBB traction power network was required in Oberoesterreich. Therefore, OeBB installed a the new converter station Timelkam containing two converter units having an active power of 30 MW each. The energy is supplied by the 3 AC 110 kV 50 Hz network of Energie AG Oberoesterreich. The new converter station Timelkam was commissioned in October 2009. (orig.)

  6. Effect of Bifidobacterium longum BB536 yogurt administration on the intestinal environment of healthy adults.

    OpenAIRE

    Ogata, T; Kingaku, M; Yaeshima, T.; Teraguchi, S; Fukuwatari, Y; Ishibashi, N.(Department of Physics, Osaka University, Toyonaka, Osaka 560-0043, Japan); Hayasawa, H.; Fujisawa, T.; Iino, H.

    2011-01-01

    A yogurt supplemented with B. longum BB536 was administered at 250 ml per day for 2 weeks to six healthy volunteers. The effects on the fecal microflora, fecal putrefactive substances, fecal enzymatic activities and fecal properties were examined and compared with the effects of standard yogurt. A significant increase (p<0.05) in the proportion of Bifidobacterium in the fecal microflora was observed following ingestion of yogurt containing B. longum BB536. The numbers of Lactobacillus also...

  7. An investigation of hierachical protein recruitment to the inhibitory platelet receptor, G6B-b.

    Science.gov (United States)

    Coxon, Carmen H; Sadler, Amanda J; Huo, Jiandong; Campbell, R Duncan

    2012-01-01

    Platelet activation is regulated by both positive and negative signals. G6B-b is an inhibitory platelet receptor with an immunoreceptor tyrosine-based inhibitory motif (ITIM) and an immunoreceptor tyrosine-based switch motif (ITSM). The molecular basis of inhibition by G6B-b is currently unknown but thought to involve the SH2 domain-containing tyrosine phosphatase SHP-1. Here we show that G6B-b also associates with SHP-2, as well as SHP-1, in human platelets. Using a number of biochemical approaches, we found these interactions to be direct and that the tandem SH2 domains of SHP-2 demonstrated a binding affinity for G6B-b 100-fold higher than that of SHP-1. It was also observed that while SHP-1 has an absolute requirement for phosphorylation at both motifs to bind, SHP-2 can associate with G6B-b when only one motif is phosphorylated, with the N-terminal SH2 domain and the ITIM being most important for the interaction. A number of other previously unreported SH2 domain-containing proteins, including Syk and PLCγ2, also demonstrated specificity for G6B-b phosphomotifs and may serve to explain the observation that G6B-b remains inhibitory in the absence of both SHP-1 and SHP-2. In addition, the presence of dual phosphorylated G6B-b in washed human platelets can reduce the EC(50) for both CRP and collagen.

  8. An investigation of hierachical protein recruitment to the inhibitory platelet receptor, G6B-b.

    Directory of Open Access Journals (Sweden)

    Carmen H Coxon

    Full Text Available Platelet activation is regulated by both positive and negative signals. G6B-b is an inhibitory platelet receptor with an immunoreceptor tyrosine-based inhibitory motif (ITIM and an immunoreceptor tyrosine-based switch motif (ITSM. The molecular basis of inhibition by G6B-b is currently unknown but thought to involve the SH2 domain-containing tyrosine phosphatase SHP-1. Here we show that G6B-b also associates with SHP-2, as well as SHP-1, in human platelets. Using a number of biochemical approaches, we found these interactions to be direct and that the tandem SH2 domains of SHP-2 demonstrated a binding affinity for G6B-b 100-fold higher than that of SHP-1. It was also observed that while SHP-1 has an absolute requirement for phosphorylation at both motifs to bind, SHP-2 can associate with G6B-b when only one motif is phosphorylated, with the N-terminal SH2 domain and the ITIM being most important for the interaction. A number of other previously unreported SH2 domain-containing proteins, including Syk and PLCγ2, also demonstrated specificity for G6B-b phosphomotifs and may serve to explain the observation that G6B-b remains inhibitory in the absence of both SHP-1 and SHP-2. In addition, the presence of dual phosphorylated G6B-b in washed human platelets can reduce the EC(50 for both CRP and collagen.

  9. Combined delivery of PDGF-BB and BMP-6 for enhanced osteoblastic differentiation.

    Science.gov (United States)

    Demirtaş, T Tolga; Göz, Eda; Karakeçili, Ayşe; Gümüşderelioğlu, Menemşe

    2016-01-01

    Natural microenvironment during bone tissue regeneration involves integration of multiple biological growth factors which regulate mitogenic activities and differentiation to induce bone repair. Among them platelet derived growth factor (PDGF-BB) and bone morphogenic protein-6 (BMP-6) are known to play a prominent role. The aim of this study was to investigate the benefits of combined delivery of PDGF-BB and BMP-6 on proliferation and osteoblastic differentiation of MC3T3-E1 preosteoblastic cells. PDGF-BB and BMP-6 were loaded in gelatin and poly (3-hydroxybutyric acid-co-3-hydroxyvaleric acid) particles, respectively. The carrier particles were then loaded into 3D chitosan matrix fabricated by freeze drying. The fast release of PDGF-BB during 7 days was accompanied by slower and prolonged release of BMP-6. The premising release of mitogenic factor PDGF-BB resulted in an increased MC3T3-E1 cell population seeded on chitosan scaffolds. Osteogenic markers of RunX2, Col 1, OPN were higher on chitosan scaffolds loaded with growth factors either individually or in combination. However, OCN expression and bone mineral formation were prominent on chitosan scaffolds incorporating PDGF-BB and BMP-6 as a combination.

  10. Conserved hypothetical BB0462 protein enhances the transcription activity of oppAV promoter

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Borrelia burgdorferi BB0462 ORF encodes an unknown functional protein with 110 amino acids.A BLAST search in protein databases and the secondary structure being predicted by the program JUFO showed that the conserved hypothetical BB0462 protein was similar to the members of the YbaB protein family in both amino acid composition and protein structure.The co-transformation of BB0462 ORF and oppA upstream regulation DNA into E.coli host cells and β-galactosidase activity assay demonstrated that the BB0462 protein enhanced the transcriptional activity of the oppAV promoter,but does not affect those of oppAⅠ,Ⅱ,Ⅲ and Ⅳ promoters.Analysis of DNA retardation and competitive repression also confirmed that the BB0462 protein bound to the 409 bp upstream regulation DNA fragment close to the initiation codon of the oppAV gene.All data in our study suggested that the BB0462 protein was involved in the transcriptional regulation of the oppAV gene

  11. Reversal of impaired wound healing in irradiated rats by platelet-derived growth factor-BB

    Energy Technology Data Exchange (ETDEWEB)

    Mustoe, T.A.; Purdy, J.; Gramates, P.; Deuel, T.F.; Thomason, A.; Pierce, G.F. (Washington Univ. Medical Center, St. Louis, MO (USA))

    1989-10-01

    This study examined the potential influence of platelet-derived growth factor-BB homodimers (PDGF-BB) on surgical incisions in irradiated animals with depressed wound healing. Rats were irradiated with either 800 rads total body or 2,500 rads surface irradiation. Parallel dorsal skin incisions were made 2 days later, and PDGF-BB was applied topically a single time to one of two incisions. In total body-irradiated rats, bone marrow-derived elements were severely depressed, wound macrophages were virtually eliminated, and PDGF-BB treatment was ineffective. However, in surface-irradiated rats, PDGF-BB treatment recruited macrophages into wounds and partially reversed impaired healing on day 7 (p less than 0.005) and day 12 (p less than 0.001). PDGF-BB-treated wounds were 50 percent stronger than the paired control wounds. The results suggest PDGF requires bone marrow-derived cells, likely wound macrophages, for activity and that it may be useful as a topical agent in postirradiation surgical incisions.

  12. Non-resonant Higgs-pair production in the b anti bb anti b final state at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Wardrope, David; Jansen, Eric; Konstantinidis, Nikos; Cooper, Ben; Falla, Rebecca; Norjoharuddeen, Nurfikri [University College London, Department of Physics and Astronomy, London (United Kingdom)

    2015-05-15

    We present a particle-level study of the Standard Model non-resonant Higgs-pair production process in the b anti bb anti b final state, at the Large Hadron Collider at √(s) = 14 TeV. Each Higgs boson is reconstructed from a pair of close-by jets formed with the anti-k{sub t} jet clustering algorithm, with radius parameter R = 0.4. Given the kinematic properties of the produced Higgs bosons, this Higgs reconstruction approach appears to be more suitable than the use of largeradius jets that was previously proposed in the literature.We find that the sensitivity for observing this final state can be improved significantly when the full set of uncorrelated angular and kinematic variables of the 4b system is exploited, leading to a statistical significance of 1.8 per experiment with an integrated luminosity of 3 ab{sup -1}. (orig.)

  13. Autophagy inhibits PDGF-BB-induced calcification in vascular smooth muscle cells

    Institute of Scientific and Technical Information of China (English)

    PEI Qian-qian; MEI Han; ZHANG Xu-hui; DONG Li-hua

    2016-01-01

    AIM:To investigate the relationship between autophagy and calcification in vascular smooth muscle cells ( VSMCs) after platelet-derived growth factor (PDGF)-BB stimulation.METHODS:Cultured VSMCs were stimulated with PDGF-BB for different time, the expression of vascular calcification-related proteins and autophagy-related proteins were detected by Western blot .The interaction be-tween Beclin1 and PI3KC3 was detected by co-immunoprecipitation.RESULTS: The expression of BMP2 and ALP showed a trend from decline to rise.ALP slumped at 12 h, and BMP2 slumped at 6 h.Moreover, the expression of Beclin-1 showed a trend from rise to decline, and peaked at 12 h.The conversion of LC3-ⅠtoⅡincreased in a time-dependent manner , and peaked at 24 h.The ex-pression of BMP2 and ALP was increased in VSMCs incubated with PDGF-BB and autophagy inhibitor 3-MA, compared with PDGF-BB-stimulated VSMCs.Furthermore, the interaction between Beclin1 and PI3KC3 was enhanced at 6 h after PDGF-BB stimulated, peaked at 12 h, and kept in high level at 24 h.Moreover, the phosphorylation level of Beclin 1 was enhanced by PDGF-BB stimulation, and peaked at 6 h.CONCLUSION:Our findings demonstrate that PDGF-BB-induced autophagy inhibits VSMC calcification by en-hancing Beclin1 phosphorylation and interaction between Beclin 1 and PI3KC3.

  14. Cataclysms and Catastrophes: A Case Study of Improving K-12 Science Education Through a University Partnership

    Science.gov (United States)

    Fennell, T.; Ellins, K. K.; Morris, M.; Christeson, G.

    2003-12-01

    The K-12 science teacher is always seeking ways of improving and updating their curriculum by integrating the latest research into their most effective classroom activities. However, the daily demands of delivering instruction to large numbers of students coupled with the rapid advances in some fields of science can often overwhelm this effort. The NSF-sponsored Cataclysms and Catastrophes curriculum, developed by scientists from the The University of Texas at Austin Institute for Geophysics (UTIG) and Bureau of Economic Geology (BEG), middle and high school teachers, and UT graduate students (NSF GK-12 fellows) working together through the GK-12 program, is a textbook example of how universities can facilitate this quest, benefiting education at both K-12 and university levels. In 1992, "The Great K-T Extinction Debate" was developed as an activity in the Planet Earth class at the Liberal Arts and Science Academy of Austin as an interdisciplinary approach to science. Taking advantage of the media attention generated by the impact scenario for the K-T extinction, the activity consists of students participating in a simulated senate hearing on the potential causes of the K-T extinction and their implications for society today. This activity not only exposes students to the wide range of science involved in understanding mass extinctions, but also to the social, political and economic implications when this science is brought into the public arena and the corresponding use of data in decision making and disaster preparedness. While "The Great K-T Extinction Debate" was always a popular and effective activity with students, it was in desperate need of updating to keep pace with the evolving scientific debate over the cause of the K-T extinction and the growing body of impact evidence discovered over the past decade. By adding two inquiry-based learning activities that use real geophysical data collected by scientists studying the buried Chicxulub feature as a

  15. Compositional and Geochronological Constraints on the Lunar Cataclysm from Planetary Samples

    Science.gov (United States)

    Cohen, Barbara A.

    2008-01-01

    Radiometric dating and compositional clustering of lunar impact-melt rocks form the backbone of the lunar cataclysm hypothesis. Precise age determinations of Apollo and Luna impact-melt rocks define the classic formulation of the cataclysm: a large number of samples 3.9 Ga old, a steep decline after 3.9 Ga, and few impact rocks older than 4.0 Ga. Lunar meteorites more randomly sample the lunar surface, but impact-melt clasts in these rocks show the same apparent age cutoff at 4.0 Ga (though their ages extend approx.500 Myr later). Neither do impact-formed glass spherules and fragments, formed by impacts of all sizes throughout lunar history, predate 4.0 Ga. Geological associations between compositional groups of impact-melt rocks and specific impact basins imply that five large basins formed on the Moon within 200 Myr but a counter-argument postulates they are all products of the Imbrium basin-forming impact; it is not yet proven whether groups of impact melt that are resolvable from each other in age and in trace-element composition represent multiple impacts. The 3.9 Ga age peak and subsequent steep decline are not well mirrored in meteorite data. Radiometric ages in ordinary chondrites and HED meteorites peak around 3.9 Ga but ages older and younger than 3.9 Ga are common. Among Martian meteorites, there is a single impact-related age: ALH 84001 was shocked at 3.92 Ga. Differences in relative impact velocity, impact-melt production, and sampling rate could explain differences between the meteorite and lunar records. One way to anchor the early end of the lunar flux is to directly sample the impact-melt sheet of a large lunar basin distant from Imbrium, such as the South Pole-Aitken basin, where melt rocks probably still resides on the basin floor and could be directly sampled by a human or robotic mission.

  16. New variables in M5 (NGC 5904) and some identification corrections

    CERN Document Server

    Ferro, A Arellano; Giridhar, S; Luna, A; Muneer, S

    2015-01-01

    We report twelve variables not previously detected in the globular cluster M5 (NGC 5904); one SX Phe and eleven semi-regular variables (SR). Their identifications, equatorial coordinates, ephemerides, and light curves are given. Furthermore, we have explored the light curves of a group of stars whose variability has not been confirmed and that are marked as probable non- variables in the CVSGC. Finally, we offer detailed identifications for some of the known variables in crowded regions that were misidentified in previous studies. We shall also address the cases of the cataclysmic variable or U Gem type V101 and of the variable blue straggler V159.

  17. Beneficial effect of the Ca2+ antagonist, nimodipine, on existing diabetic neuropathy in the BB/Wor rat

    OpenAIRE

    Gispen, W.H.; Kappelle, A. C.; Biessels, G.J.; Bravenboer, B.; Buren, T. van; Traber, J.; de Wildt, D J

    1994-01-01

    1. Neuropathy is a frequently diagnosed complication of diabetes mellitus. Effective pharmacotherapy is not available. 2. The spontaneously diabetic BB/Wor rats develop secondary complications like neuropathy as do human diabetic patients. 3. BB/Wor rats treated with insulin via a subcutaneous implant show a significant impairment of sensory and motor nerve conduction velocity 6 weeks after the onset of diabetes mellitus. 4. Intraperitoneal treatment of diabetic BB/Wor rats with the Ca2+ anta...

  18. Effect of repeated oral administration of Bifidobacterium longum BB536 on apomorphine-induced rearing behavior in mice

    OpenAIRE

    ORIKASA, Shuzo; NABESHIMA, Kazumi; Iwabuchi, Noriyuki; Xiao, Jin-zhong

    2016-01-01

    Schizophrenia is a chronic psychiatric illness. Disruption of the dopaminergic system has been suggested to be the pathogenic cause of this disease. The effect of Bifidobacterium longum BB536 (BB536) on schizophrenic behavior was investigated in an animal model. Daily administration of BB536 (109 CFU/mouse, p.o. for 2 weeks) was found to reduce rearing behavior augmented by the dopamine receptor agonist apomorphine and to decrease the resting level of plasma corticosterone and the ratio of ky...

  19. Evaluation of Borrelia burgdorferi BbHtrA Protease as a Vaccine Candidate for Lyme Borreliosis in Mice.

    Directory of Open Access Journals (Sweden)

    Amy J Ullmann

    Full Text Available Borrelia burgdorferi synthesizes an HtrA protease (BbHtrA which is a surface-exposed, conserved protein within Lyme disease spirochetes with activity toward CheX and BmpD of Borrelia spp, as well as aggrecan, fibronectin and proteoglycans found in skin, joints and neural tissues of vertebrates. An antibody response against BbHtrA is observed in Lyme disease patients and in experimentally infected laboratory mice and rabbits. Given the surface location of BbHtrA on B. burgdorferi and its ability to elicit an antibody response in infected hosts, we explored recombinant BbHtrA as a potential vaccine candidate in a mouse model of tick-transmitted Lyme disease. We immunized mice with two forms of BbHtrA: the proteolytically active native form and BbHtrA ablated of activity by a serine to alanine mutation at amino acid 226 (BbHtrA(S226A. Although inoculation with either BbHtrA or BbHtrA(S226A produced high-titer antibody responses in C3H/HeJ mice, neither antigen was successful in protecting mice from B. burgdorferi challenge. These results indicate that the search for novel vaccine candidates against Lyme borreliosis remains a challenge.

  20. Effect of repeated oral administration of Bifidobacterium longum BB536 on apomorphine-induced rearing behavior in mice.

    Science.gov (United States)

    Orikasa, Shuzo; Nabeshima, Kazumi; Iwabuchi, Noriyuki; Xiao, Jin-Zhong

    2016-01-01

    Schizophrenia is a chronic psychiatric illness. Disruption of the dopaminergic system has been suggested to be the pathogenic cause of this disease. The effect of Bifidobacterium longum BB536 (BB536) on schizophrenic behavior was investigated in an animal model. Daily administration of BB536 (10(9) CFU/mouse, p.o. for 2 weeks) was found to reduce rearing behavior augmented by the dopamine receptor agonist apomorphine and to decrease the resting level of plasma corticosterone and the ratio of kynurenine to tryptophan. These results suggest the potential of BB536 for supplemental treatment of the symptoms of schizophrenia.

  1. Platelet Derived Growth Factor BB: A “Must-have” Therapeutic Target “Redivivus” in Ovarian Cancer

    Science.gov (United States)

    MARIA CIMPEAN, ANCA; MARCEL COBEC, IONUT; AMALIA CEAUȘU, RALUCA; POPESCU, ROXANA; TUDOR, ANCA; RAICA, MARIUS

    2016-01-01

    Background: We aimed to validate PDGF-BB protein expression by RNAscope, a sensitive method for PDGF-BB mRNA evaluation on paraffin embedded (FFPE) specimens of ovarian tumors. Materials and Methods: Seventy-five FFPE ovarian cancer biopsies were assessed by immunohistochemistry followed by PDGF-BB mRNA RNAscope validation. Results and Conclusion: Dual PDGF-BB expression in tumor and stromal cells have been observed, being highly suggestive for PDGF-BB mediated stromal-tumor cells reciprocal interaction in ovarian cancer (p=0.008). It seems that the nuclear expression of the PDGF-BB represents a negative prognostic factor in ovarian tumors. Being a controversial issue in the literature, PDGF-BB nuclear expression detected by immunohistochemistry was validated by RNAscope in situ hybridization. More than 65% of cases had PDGF-BB mRNA amplification, confirming immunohistochemical results. We herein validated PDGF-BB as a potential therapeutic and prognostic tool of ovarian cancer aggressiveness. PMID:27807074

  2. Effects of Bifidobacterium longum BB536 on lipid profile and histopathological changes in hypercholesterolaemic rats.

    Science.gov (United States)

    Al-Sheraji, S H; Amin, I; Azlan, A; Manap, M Y; Hassan, F A

    2015-01-01

    The present study investigated the effects of Bifidobacterium longum BB536 on lipid profile, liver and kidney function, and body fat in hypercholesterolaemic rats. 40 Sprague-Dawley rats were randomly divided into five groups. The negative control group received a standard diet. The positive control group received a cholesterol-enriched diet, whereas the intervention groups received a cholesterol-enriched diet supplemented with B. longum BB536 alone or in combination with inulin or Mangifera pajang fibrous polysaccharides. After 8 weeks, plasma lipids, and liver and kidney function were tested. Intake of the cholesterol-enriched diet increased total cholesterol, alanine aminotransferase, gamma-glutamyl transferase, creatinine, urea, liver weight, adipose tissue weight, liver lipid deposition and adipocyte size. B. longum BB536 supplementation significantly reduced total cholesterol, liver lipid deposition and adipocyte size, and positively affected liver and kidney function. These effects were significantly increased in the presence of inulin and M. pajang fibrous polysaccharides.

  3. Total lymphoid irradiation prevents diabetes mellitus in the Bio-Breeding/Worcester (BB/W) rat

    Energy Technology Data Exchange (ETDEWEB)

    Rossini, A.A.; Slavin, S.; Woda, B.A.; Geisberg, M.; Like, A.A.; Mordes, J.P.

    1984-06-01

    Total lymphoid irradiation (TLI) at doses of 2200 rads or greater prevented diabetes in susceptible BB/W rats. Two of 29 (7%) treated rats became diabetic compared with 23 of 39 (59%) controls. TLI did not, however, prevent insulitis or thyroiditis in nondiabetic rats, nor did it restore the depressed concanavalin-A responsiveness of BB rat lymphocytes. T-lymphocyte subset proportions were the same in both groups. TLI was associated with significant radiation-related mortality, and nondiabetic TLI-treated rats weighed significantly less than controls. It was concluded that TLI is effective in the prevention of BB rat diabetes. However, TLI fails to correct the subclinical immunologic abnormalities of the model and is associated with significant morbidity.

  4. Hypocholesterolaemic effect of yoghurt containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536.

    Science.gov (United States)

    Al-Sheraji, Sadeq Hasan; Ismail, Amin; Manap, Mohd Yazid; Mustafa, Shuhaimi; Yusof, Rokiah Mohd; Hassan, Fouad Abdulrahman

    2012-11-15

    The effect of a yoghurt supplement containing Bifidobacterium pseudocatenulatum G4 or Bifidobacterium longum BB536 on plasma lipids, lipid peroxidation and the faecal excretion of bile acids was examined in rats fed a cholesterol-enriched diet. After 8 weeks, the rats in the positive control (PC) group who were fed the cholesterol-enriched diet showed significant increases in plasma total cholesterol (TC), low-density lipoprotein (LDL) cholesterol, and malondialdehyde (MDA). However, groups fed a cholesterol-enriched diet supplemented with yoghurt containing B. pseudocatenulatum G4 or B. longum BB536 had significantly lower plasma TC, LDL-C, very-low-density lipoprotein (VLDL) cholesterol, and MDA than had the PC group after 8 weeks of treatment. In addition, faecal excretion of bile acids was markedly increased in the rats fed the yoghurt containing B. pseudocatenulatum G4 or B. longum BB536 as compared to the PC and NC groups.

  5. Matrine inhibits proliferation of mouse skin fibroblasts induced by platelet-derived growth factor-BB

    Institute of Scientific and Technical Information of China (English)

    WU Yan-an; GAO Chun-fang; WANG Hao; HUANG Chao; KONG Xian-tao

    2001-01-01

    To study the effect of matrine on proliferation of mouse skin fibroblasts induced by platelet-derived growth factor-BB (PDGF-BB). Methods: Mouse skin fibroblasts were obtained from newborn ⅠCR mice and propagated in vitro. Proliferation of cell was analyzed by mitochondrial reduction of tetrazolium salt MTT and actual cell count. Results: Matrine (50 to 500 μg/ml) caused dose-dependent reduction of serum-stimulated cell growth. Growth inhibition was totally reversed after removal of the drug. Matrine also inhibited PDGF-BB induced cell growth dose-dependently. Conclusion: Matrine exhibits potent anti-proliferation effect on mouse skin fibroblast. This effect appears to be mediated by decrease of PDGF-induced growth. These results suggest that matrine might have preventive and therapeutic implication in skin fibrosis.

  6. A Note on n-BB-tilting Modules%关于n-BB-倾斜模的一个注记

    Institute of Scientific and Technical Information of China (English)

    郑立景; 吴春生

    2014-01-01

    设A是一个域k上的基本有限维代数.本文证明了如果AT是一个n-BB-倾斜模,那么TB亦为n-BB-倾斜模,其中B=End(AT).进一步,如果AT是一个n-APR-倾斜模,那么TB亦为n-APR-倾斜模.最后,把本文的结果应用到一个具有n-APR-倾斜模AT的代数A上,得到A是n-表示-有限的(无限的)当且仅当B是n-表示-有限的(无限的).

  7. Pengaruh Ergonomi Organisasi terhadap Motivasi Kerja Perawat Pelaksana di Ruang Rawat Inap Rumah Sakit Tk II Putri Hijau Kesdam I/BB Medan

    OpenAIRE

    Suharto

    2013-01-01

    The organization at workplace is a place where employees interact with others in doing their jobs. An ergonomic organizational design is needed to make the employees do their job properly. The aim of the research was to analyze the influence of organizational ergonomy on work motivation of the nurses on duty in the in-patient wards of Putri Hijau Kesdam I/BB Level II Hospital, Medan. The purpose of this explanatory study was to explain the influence of inter-variables through statistic an...

  8. Friction and impact sensitivities of explosives: A comparative study. [HMX, CP, barium styphnate, RX26BB, RX26BH, PYX, BTF

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Pu Sen; Hall, G.F.

    1988-01-01

    Impact and friction sensitivities of explosives were tested by the ''one-shot'' method. The Bruceton statistical method was used to derive 50% initiation levels. The materials tested include: PETN, HMX, CP, barium styphnate, TATB, RX26BB, RX26BH, PYX, BTF and various types of plastic bonded explosives (PBX). Some samples were investigated for aging effects, physical variables, and the effect of manufacturing parameters on these sensitivities. The results proved to have comparative values. CP and barium styphnate were found to be the most sensitive among the samples tested, while TATB was found to be relatively insensitive. 9 refs., 3 tabs.

  9. On the possibility to detect the Higgs decay H→bb{sup -bar} in the associated Z+bb{sup -bar} production at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Lipatov, A. V., E-mail: lipatov@theory.sinp.msu.ru [Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, 119991, Moscow (Russian Federation); Joint Institute for Nuclear Research, 141980, Dubna, Moscow Region (Russian Federation); Zotov, N. P. [Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, 119991, Moscow (Russian Federation)

    2015-05-05

    We investigate the possibility to detect the scalar Higgs boson decay H→bb{sup -bar} in the associated Z and bb{sup -bar} production at the LHC using the k{sub T}-factorization QCD approach. Our consideration is based on the off-shell (i.e. depending on the transverse momenta of initial quarks and gluons) production amplitudes of q{sup ∗}q{sup -bar∗}→ZH→Zq{sup ′}q{sup -bar′}, q{sup ∗}q{sup -bar∗}→Zq{sup ′}q{sup -bar′}, and g{sup ∗}g{sup ∗}→Zq{sup ′}q{sup -bar′} partonic subprocesses supplemented with the Catani–Ciafoloni–Fiorani–Marchesini (CCFM) dynamics of parton densities in a proton. We argue that the H→bb{sup -bar} signal could be observed at large transverse momenta near the Higgs boson peak despite the overwhelming QCD background, and we point out the important role of angular correlations between the produced Z boson and b-quarks.

  10. 基于BB-BC的粒子滤波算法研究%Particle Filter Based on BB-BC Algorithm

    Institute of Scientific and Technical Information of China (English)

    刘钊; 冯新喜; 鹿传国; 孔云波

    2012-01-01

    Particle filter is the major method of solving the issue of the nonlinear and non-Gaussian system. To overcome the impact of particle degeneration to the performance of particle filter, an intelligent particle filter algorithm based on the Big Bang-Big Crunch (BB-BC) optimization algorithm is proposed. By applying it into resampling, the particle degeneration problem can be resolved by iterative mechanism. The simulation result indicates that compared with standard particle filter, the BB-BC particle filter algorithm is simpler and has better filter effects.%粒子滤波是目前解决非线性、非高斯系统问题的主流方法,为克服粒子退化对粒子滤波性能的影响,提出了一种基于大爆炸-大坍塌(BB-BC)优化算法的智能化粒子滤波算法.将大爆炸-大坍塌优化算法应用于重采样,以迭代机制设计解决粒子退化问题.仿真结果表明,该算法与标准粒子滤波算法相比计算简单,滤波效果优于标准粒子滤波算法.

  11. Study of BB ¯*/DD ¯* bound states in a Bethe-Salpeter approach

    Science.gov (United States)

    He, Jun

    2014-10-01

    In this work the BB ¯*/DD ¯* system is studied in the Bethe-Salpeter approach with quasipotential approximation. In our calculation both direct and cross diagrams are included in the one-boson-exchange potential. The numerical results indicate the existence of an isoscalar bound state DD ¯* with JPC=1++, which may be related to the X(3872). In the isovector sector, no bound state is produced from the interactions of DD ¯* and BB ¯*, which suggests the molecular state explanations for Zb(10610) and Zc(3900) are excluded.

  12. Adli Tıbbı Bugune Getirenler-I

    Directory of Open Access Journals (Sweden)

    Nevzat Alkan

    2000-08-01

    şlamış ve bu yangında ölenlerin kimliklerinin tespiti konusunda başarılı olmuştur. Bu olayı takiben, mevcut bilgi ve tecrübesini literatür çalışmaları ile desteklemiş ve "Adli Tıpta Dişçilik Sanatı" başlığında bir yazı hazırlamıştır. Söz konusu çalışma 1898 yılında, Masson et Cie tarafından basılarak yayınlanmıştır. Dr. Oscar Amoedo bu çalışması ile adli tıbbın diş hekimliği alanındaki yoğun noksanını büyük bir ölçüde doldurmuş ve adli diş hekimliğini kimliklendirme ve müstakil bir çalışma alanı olarak, gerek diş hekimliği içerisinde, gerekse adli tıp içerisinde tanıtmış ve kabul ettirmiştir. Söz konusu kitap, adli diş hekimliği alanında yayınlanmış ilk kapsamlı kitaptır ve konu ile ilgili dönemine ait mevcut tüm gelişmeleri içermektedir. Dr. Oscar Amoedo, dışa dönük bir kişilik ve kelimenin tam anlamı ile mükemmel bir öğretmendi. Diş hekimliği ve tıp ile ilişkili 14 birliğe üye idi. Bu birliklerin 8 ' inde onur üyesi, 4 ' ünde ise iletişimden sorumlu üye olarak yer almıştır. İyi düzeyde İspanyolca, İngilizce ve Fransızca bilen Dr. Oscar Amoedo, yaşamı boyunca 57 profesyonel kongreye katılmış ve bu kongrelerde çok sayıda tebliğ sunmuş, tartışmaya katılmış ya da tartışmayı yönetmiştir. 1936 yılında, 73 yaşında iken katıldığı toplantı iştirak ettiği son bilimsel etkinliktir. Dr. Oscar Amoedo 25 Eylül 1945 tarihinde, 82 yaşında iken, evinde hayata gözlerini yummuştur. Dr. Oscar Amoedo, günümüzde Adli Diş Hekimliği ' nin kurucusu olarak kabul edilmektedir. * Bu yazı, Uzm. Dr. Nevzat Alkan tarafından, editörleri I.R. Hill, S. Keiser-Nielsen, Y. Vermylen, E. Free, E.D. Valck ve E. Tormans olan, "Forensic Odontology: Its Scope and History" başlıklı kitaptan derlenmiştir.

  13. The Plant-Derived Bauhinia bauhinioides Kallikrein Proteinase Inhibitor (rBbKI) Attenuates Elastase-Induced Emphysema in Mice.

    Science.gov (United States)

    Martins-Olivera, Bruno Tadeu; Almeida-Reis, Rafael; Theodoro-Júnior, Osmar Aparecido; Oliva, Leandro Vilela; Neto Dos Santos Nunes, Natalia; Olivo, Clarice Rosa; Vilela de Brito, Marlon; Prado, Carla Máximo; Leick, Edna Aparecida; Martins, Mílton de Arruda; Oliva, Maria Luiza Vilela; Righetti, Renato Fraga; Tibério, Iolanda de Fátima Lopes Calvo

    2016-01-01

    Background. Elastase mediates important oxidative actions during the development of chronic obstructive pulmonary disease (COPD). However, few resources for the inhibition of elastase have been investigated. Our study evaluated the ability of the recombinant plant derived Bauhinia bauhinioides Kallikrein proteinase Inhibitor (rBbKI) to modulate elastase-induced pulmonary inflammation. Methods. C57Bl/6 mice were given intratracheal elastase (ELA group) or saline (SAL group) and were treated intraperitoneally with rBbKI (ELA-rBbKI and SAL-rBbKI groups). At day 28, the following analyses were performed: (I) lung mechanics, (II) exhaled nitric oxide (ENO), (III) bronchoalveolar lavage fluid (BALF), and (IV) lung immunohistochemical staining. Results. In addition to decreasing mechanical alterations and alveolar septum disruption, rBbKI reduced the number of cells in the BALF and decreased the cellular expression of TNF-α, MMP-9, MMP-12, TIMP-1, eNOS, and iNOS in airways and alveolar walls compared with the ELA group. rBbKI decreased the volume proportion of 8-iso-PGF2α, collagen, and elastic fibers in the airways and alveolar walls compared with the ELA group. A reduction in the number of MUC-5-positive cells in the airway walls was also observed. Conclusion. rBbKI reduced elastase-induced pulmonary inflammation and extracellular matrix remodeling. rBbKI may be a potential pharmacological tool for COPD treatment.

  14. A Back-To-Back Barrier-N-N+ (bbBNN)Diode Tripler at 200 GHz

    Science.gov (United States)

    Choudhury, Debabani; Raisanen, Anti V.; Smith, R. Peter; Frerking, Margaret A.

    1993-01-01

    This paper describes the performance of planar back-to-back Barrier-N-N+ (bbBNN) devices for mm and submm wave multiplier applications. A technique has been developed for characterizing planar bbBNN devices with Vector Network Analyzer, which gives both the series resistance and voltage dependent capacitance of the device.

  15. Confirmation of a predicted lack of IgE binding to Cry3Bb1 from genetically modified (GM) crops.

    Science.gov (United States)

    Nakajima, Osamu; Koyano, Satoru; Akiyama, Hiroshi; Sawada, Jun-Ichi; Teshima, Reiko

    2010-04-01

    Some GM crops including MON863 corn and stack varieties contain Cry3Bb1 protein. Cry3Bb1 is very important from the standpoint of assessing the safety of GM crops. In this study Cry3Bb1 was assessed from the standpoint of possible binding to IgE from allergy patients. First, an ELISA that was improved in our laboratory was used to test serum samples from 13 corn allergy patients in the United States with recombinant Cry3Bb1 expressed in Escherichia coli, and serum samples from 55 patients in Japan with various food allergies were also assayed. Two samples from the Japanese allergy patients were suspected of being positive, but Western blotting analysis with purified Cry3Bb1 indicated that the binding between IgE and Cry3Bb1 was nonspecific. Ultimately, no specific binding between IgE and recombinant Cry3Bb1 was detected. Next, all proteins extracted from MON863 corn and non-GM corn were probed with IgE antibodies in serum samples from the corn allergy patients by Western blotting, but the staining patterns of MON863 and non-GM corn were similar, meaning that unintended allergic reactions to MON863 are unlikely to occur. Our study provides additional information that confirms the predicted lack of IgE binding to Cry3Bb1 in people with existing food allergies. Copyright 2009 Elsevier Inc. All rights reserved.

  16. The Plant-Derived Bauhinia bauhinioides Kallikrein Proteinase Inhibitor (rBbKI Attenuates Elastase-Induced Emphysema in Mice

    Directory of Open Access Journals (Sweden)

    Bruno Tadeu Martins-Olivera

    2016-01-01

    Full Text Available Background. Elastase mediates important oxidative actions during the development of chronic obstructive pulmonary disease (COPD. However, few resources for the inhibition of elastase have been investigated. Our study evaluated the ability of the recombinant plant derived Bauhinia bauhinioides Kallikrein proteinase Inhibitor (rBbKI to modulate elastase-induced pulmonary inflammation. Methods. C57Bl/6 mice were given intratracheal elastase (ELA group or saline (SAL group and were treated intraperitoneally with rBbKI (ELA-rBbKI and SAL-rBbKI groups. At day 28, the following analyses were performed: (I lung mechanics, (II exhaled nitric oxide (ENO, (III bronchoalveolar lavage fluid (BALF, and (IV lung immunohistochemical staining. Results. In addition to decreasing mechanical alterations and alveolar septum disruption, rBbKI reduced the number of cells in the BALF and decreased the cellular expression of TNF-α, MMP-9, MMP-12, TIMP-1, eNOS, and iNOS in airways and alveolar walls compared with the ELA group. rBbKI decreased the volume proportion of 8-iso-PGF2α, collagen, and elastic fibers in the airways and alveolar walls compared with the ELA group. A reduction in the number of MUC-5-positive cells in the airway walls was also observed. Conclusion. rBbKI reduced elastase-induced pulmonary inflammation and extracellular matrix remodeling. rBbKI may be a potential pharmacological tool for COPD treatment.

  17. Creatine kinase BB and beta-2-microglobulin as markers of CNS metastases in patients with small-cell lung cancer

    DEFF Research Database (Denmark)

    Pedersen, A G; Bach, F W; Nissen, Mogens Holst

    1985-01-01

    Creatine kinase (CK) and its BB isoenzyme (CK-BB) were measured in CSF in 65 evaluable patients suspected of CNS metastases secondary to small-cell lung cancer (SCLC). In addition, CSF and plasma levels of beta-2-microglobulin (beta-2-m) were measured in a group of 73 evaluable patients. Of the 65...

  18. The ability of the biological control agent Bacillus subtilis, strain BB, to colonise vegetable brassicas endophytically following seed inoculation

    NARCIS (Netherlands)

    Wulff, E.G.; Vuurde, van J.W.L.; Hockenhull, J.

    2003-01-01

    The ability of Bacillus subtilis, strain BB, to colonise cabbage seedlings endophytically was examined following seed inoculation. Strain BB was recovered from different plant parts including leaves (cotyledons), stem (hypocotyl) and roots. While high bacterial populations persisted in the roots and

  19. SCN1Bb R214Q found in 3 patients: 1 with Brugada syndrome and 2 with lone atrial fibrillation

    DEFF Research Database (Denmark)

    Olesen, Morten S; Holst, Anders G; Haunsø, Stig

    2012-01-01

    BACKGROUND: SCN1Bb encodes the ß-subunit of the sodium channel. A mutation in SCN1Bb R214Q has recently been shown both to increase the Kv4.3 current and to decrease the sodium current. The variant was suggested to increase the susceptibility to Brugada syndrome (BrS). OBJECTIVE: To sequence...

  20. Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters.

    Science.gov (United States)

    Tu, T H; Kim, C-S; Kang, J-H; Nam-Goong, I S; Nam, C W; Kim, E S; Kim, Y I; Choi, J I; Kawada, T; Goto, T; Park, T; Yoon Park, J H; Choi, M-S; Yu, R

    2014-08-01

    4-1BB, a member of the TNF receptor superfamily, has a role in various inflammatory pathologies through its interaction with 4-1BB ligand. We previously demonstrated that it participates in initiating and promoting obesity-induced adipose inflammation in a rodent model. In this study, we examined whether 4-1BB is related to obesity-induced adipose inflammation and metabolic parameters in humans. A total of 50 subjects, 25 obese (body mass index (BMI)≥25 kg m(-2)) and 25 lean (BMIadipose tissue were measured by quantitative real-time PCR and enzyme-linked immunosorbent assay, respectively. Inflammatory and metabolic parameters were measured by enzymatic analysis and immunoassay. Obese subjects had higher levels of both 4-1BB transcripts and s4-1BB protein in subcutaneous adipose tissue than lean controls, and the levels were correlated with BMI and the expression of inflammatory markers, as well as with serum metabolic parameters. Moreover, s4-1BB was released from human adipocytes, and elicited chemotactic responses from human monocytes/T cells as well as enhancing their inflammatory activity, indicating that it may promote human adipose inflammation. Our data demonstrate that elevated levels of 4-1BB transcripts and s4-1BB in adipose tissue are closely associated with obesity-induced inflammation and metabolic dysregulation. They suggest that both 4-1BB transcripts and s4-1BB could serve as novel biomarkers and/or therapeutic targets for obesity-induced inflammation and metabolic syndrome in humans.

  1. Measurement Properties of the Smartphone-Based B-B Score in Current Shoulder Pathologies

    Directory of Open Access Journals (Sweden)

    Claude Pichonnaz

    2015-10-01

    Full Text Available This study is aimed at the determination of the measurement properties of the shoulder function B-B Score measured with a smartphone. This score measures the symmetry between sides of a power-related metric for two selected movements, with 100% representing perfect symmetry. Twenty healthy participants, 20 patients with rotator cuff conditions, 23 with fractures, 22 with capsulitis, and 23 with shoulder instabilities were measured twice across a six-month interval using the B-B Score and shoulder function questionnaires. The discriminative power, responsiveness, diagnostic power, concurrent validity, minimal detectable change (MDC, minimal clinically important improvement (MCII, and patient acceptable symptom state (PASS were evaluated. Significant differences with the control group and significant baseline—six-month differences were found for the rotator cuff condition, fracture, and capsulitis patient groups. The B-B Score was responsive and demonstrated excellent diagnostic power, except for shoulder instability. The correlations with clinical scores were generally moderate to high, but lower for instability. The MDC was 18.1%, the MCII was 25.2%, and the PASS was 77.6. No floor effect was observed. The B-B Score demonstrated excellent measurement properties in populations with rotator cuff conditions, proximal humerus fractures, and capsulitis, and can thus be used as a routine test to evaluate those patients.

  2. Stress Analysis and Evaluating of 841BB03 Receiving Tank Ⅱ

    Institute of Scientific and Technical Information of China (English)

    WANG; Jun; DAI; Shou-tong; JING; Dan

    2013-01-01

    Entrusted by China Nuclear Engineer Ltd.,we’ve analyzed and evaluated the stress of Type 841BB03receiving tankⅡthat is one of the high level radioactive waste vitrification process equipments in 821 Plant.The equipment evaluated is classified as safety,radiochemical ClassⅠ,anti-seismic TypeⅠ.

  3. Lattice measurement of BB_s with a chiral light quark action

    Science.gov (United States)

    Blossier, B.

    2007-12-01

    The computation on the lattice of the bag parameter BB_s associated to the B-B¯ mixing amplitude in the Standard Model is presented. The estimation has been made by combining the static limit of HQET and the Neuberger light quark action which preserves the chiral symmetry on the lattice. We find BBMS¯stat(m)=0.92(3).

  4. Phase diagram of the B-B2O3 system at pressures to 24 GPa

    OpenAIRE

    Turkevich, Vladimir Z.; Turkevich, Dmitry V.; Solozhenko, Vladimir L.

    2016-01-01

    The evolution of topology of the B-B2O3 phase diagram has been studied at pressures up to 24 GPa using models of phenomenological thermodynamics with interaction parameters derived from experimental data on phase equilibria at high pressures and high temperatures.

  5. Slow-roll inflation and BB-mode angular power spectrum of CMB

    Energy Technology Data Exchange (ETDEWEB)

    Malsawmtluangi, N.; Suresh, P.K. [University of Hyderabad, School of Physics, Hyderabad (India)

    2016-05-15

    The BB-mode correlation angular power spectrum of CMB is obtained by considering the primordial gravitational waves in the squeezed vacuum state for various inflationary models and results are compared with the joint analysis of the BICEP2/Keck Array and Planck 353 GHz data. The present results may constrain several models of inflation. (orig.)

  6. A role for platelet-derived growth factor-BB in rat postpneumonectomy compensatory lung growth.

    Science.gov (United States)

    Yuan, Shizeng; Hannam, Vicky; Belcastro, Rosetta; Cartel, Nicholas; Cabacungan, Judy; Wang, Jinxia; Diambomba, Yenge; Johnstone, Leslie; Post, Martin; Tanswell, A Keith

    2002-07-01

    Unilateral pneumonectomy leads to compensatory growth in the residual lung, the mediators of which are largely unknown. We hypothesized, based on its other known roles in lung cell growth, that platelet-derived growth factor (PDGF)-BB would be an essential mediator of postpneumonectomy compensatory lung growth. Left-sided pneumonectomies were performed on 21-d-old rats, for comparison with sham-operated or unoperated control animals. Body weights were not different between groups. Right lung weights and DNA content were significantly increased (p < 0.05), compared with controls, by 10 d after pneumonectomy. The rate of DNA synthesis was maximal on d 5 postpneumonectomy. Total right lung PDGF-B mRNA and PDGF-BB protein increased after pneumonectomy, but were apparently tightly regulated, relative to total right lung beta-actin mRNA and protein content, respectively. However, PDGF-BB expression after pneumonectomy was apparently not purely constitutive, in that daily i.p. injections of a truncated soluble PDGF beta-receptor both reduced activation of the native PDGF beta-receptor, and attenuated increased lung DNA synthesis on d 3 after pneumonectomy. These findings are consistent with a critical role for PDGF-BB in postpneumonectomy lung growth.

  7. Purification and Characterization of Conjugated Bile Salt Hydrolase from Bifidobacterium longum BB536

    OpenAIRE

    Grill, J; Schneider, F.; Crociani, J.; Ballongue, J.

    1995-01-01

    Bifidobacterium species deconjugate taurocholic, taurodeoxycholic, taurochenodeoxycholic, glycocholic, glycodeoxycholic, and glycochenodeoxycholic acids. The enzyme level increases in the growth phase. No increase in activity is observed for the cytoplasmic enzyme after addition of conjugated bile acids to a stationary-phase culture. Conjugated bile salt hydrolase (BSH) was purified from Bifidobacterium longum BB536. Its apparent molecular mass in denaturing polyacrylamide gel electrophoresis...

  8. Purification and Characterization of Conjugated Bile Salt Hydrolase from Bifidobacterium longum BB536.

    Science.gov (United States)

    Grill, J; Schneider, F; Crociani, J; Ballongue, J

    1995-07-01

    Bifidobacterium species deconjugate taurocholic, taurodeoxycholic, taurochenodeoxycholic, glycocholic, glycodeoxycholic, and glycochenodeoxycholic acids. The enzyme level increases in the growth phase. No increase in activity is observed for the cytoplasmic enzyme after addition of conjugated bile acids to a stationary-phase culture. Conjugated bile salt hydrolase (BSH) was purified from Bifidobacterium longum BB536. Its apparent molecular mass in denaturing polyacrylamide gel electrophoresis was ca. 40,000 Da. The intact enzyme had a relative molecular weight of ca. 250,000 as determined by gel filtration chromatography, suggesting that the native BSH of B. longum is probably a hexamer. The purified enzyme is active towards both glycine and taurine conjugates of cholate, deoxycholate, and chenodeoxycholate. The pH optimum is in the range of 5.5 to 6.5. A loss of BSH activity is observed after incubation at temperatures higher than 42(deg)C; at 60(deg)C, 50% of the BSH activity is lost. The importance of free sulfhydryl groups at the enzyme active center is suggested. For B. longum BB536, no significant difference in the initial rate of deconjugation and enzymatic efficiency appears between bile salts. The enzymatic efficiency is higher for B. longum BB536 than for other genera. In this paper, a new method which permits a display of BSH activity directly on polyacrylamide gels is described; this method confirms the molecular weight obtained for B. longum BB536 BSH.

  9. Measurement properties of the smartphone-based B-B Score in current shoulder pathologies.

    Science.gov (United States)

    Pichonnaz, Claude; Duc, Cyntia; Gleeson, Nigel; Ancey, Céline; Jaccard, Hervé; Lécureux, Estelle; Farron, Alain; Jolles, Brigitte M; Aminian, Kamiar

    2015-10-22

    This study is aimed at the determination of the measurement properties of the shoulder function B-B Score measured with a smartphone. This score measures the symmetry between sides of a power-related metric for two selected movements, with 100% representing perfect symmetry. Twenty healthy participants, 20 patients with rotator cuff conditions, 23 with fractures, 22 with capsulitis, and 23 with shoulder instabilities were measured twice across a six-month interval using the B-B Score and shoulder function questionnaires. The discriminative power, responsiveness, diagnostic power, concurrent validity, minimal detectable change (MDC), minimal clinically important improvement (MCII), and patient acceptable symptom state (PASS) were evaluated. Significant differences with the control group and significant baseline-six-month differences were found for the rotator cuff condition, fracture, and capsulitis patient groups. The B-B Score was responsive and demonstrated excellent diagnostic power, except for shoulder instability. The correlations with clinical scores were generally moderate to high, but lower for instability. The MDC was 18.1%, the MCII was 25.2%, and the PASS was 77.6. No floor effect was observed. The B-B Score demonstrated excellent measurement properties in populations with rotator cuff conditions, proximal humerus fractures, and capsulitis, and can thus be used as a routine test to evaluate those patients.

  10. The matrix metalloproteinase inhibitor BB-94 improves the strength of intestinal anastomoses in the rat.

    NARCIS (Netherlands)

    Hingh, I.H.J.T. de; Siemonsma, M.A.; Man, B.M. de; Lomme, R.M.L.M.; Hendriks, T.

    2002-01-01

    BACKGROUND AND AIMS: The strength of intestinal anastomoses is relatively low in the first days after operation, possibly as a result of localized degradation of the supporting matrix by enzymes from the matrix metalloproteinase (MMP) family. This study examined whether BB-94, a broad spectrum

  11. The High-Metallicity Explosion Environment of the Relativistic Supernova 2009bb

    CERN Document Server

    Levesque, E M; Foley, R J; Berger, E; Kewley, L J; Chakraborty, S; Ray, A; Torres, M A P; Challis, P; Kirshner, R P; Barthelmy, S D; Bietenholz, M F; Chandra, P; Chaplin, V; Chevalier, R A; Chugai, N; Connaughton, V; Copete, A; Fox, O; Fransson, C; Grindlay, J E; Hamuy, M A; Milne, P A; Pignata, G; Stritzinger, M D; Wieringa, M H

    2009-01-01

    We investigate the environment of the nearby (d ~ 40Mpc) broad-lined Type Ic supernova SN 2009bb. This event was observed to produce a relativistic outflow likely powered by a central accreting compact object. While such a phenomenon was previously observed only in long-duration gamma-ray bursts (LGRBs), no LGRB was detected in association with SN 2009bb. Using an optical spectrum of the SN 2009bb explosion site, we determine a variety of ISM properties for the host environment, including metallicity, young stellar population age, and star formation rate. We compare the SN explosion site properties to observations of LGRB and broad-lined SN Ic host environments on optical emission line ratio diagnostic diagrams. Based on these analyses, we find that the SN 2009bb explosion site has a very high metallicity of ~2x solar, in agreement with other broad-lined SN Ic host environments and at odds with the low-redshift LGRB host environments and recently proposed maximum metallicity limits for relativistic explosions...

  12. REFIR/BB initial observations in the water vapour rotational band: Results from a field campaign

    Energy Technology Data Exchange (ETDEWEB)

    Esposito, F. [Dipartimento di Ingegneria e Fisica dell' Ambiente (DIFA)-Universita della Basilicata, Viale dell' Ateneo Lucano10, 85100 Potenza (Italy); Istituto di Metodologie per l' Analisi Ambientale, IMAA-CNR, C. da S. Loya, Tito Scalo, Potenza (Italy); Grieco, G. [Dipartimento di Ingegneria e Fisica dell' Ambiente (DIFA)-Universita della Basilicata, Viale dell' Ateneo Lucano10, 85100 Potenza (Italy); Leone, L. [Dipartimento di Ingegneria e Fisica dell' Ambiente (DIFA)-Universita della Basilicata, Viale dell' Ateneo Lucano10, 85100 Potenza (Italy); Restieri, R. [Dipartimento di Ingegneria e Fisica dell' Ambiente (DIFA)-Universita della Basilicata, Viale dell' Ateneo Lucano10, 85100 Potenza (Italy); Serio, C. [Dipartimento di Ingegneria e Fisica dell' Ambiente (DIFA)-Universita della Basilicata, Viale dell' Ateneo Lucano10, 85100 Potenza (Italy) and Istituto di Metodologie per l' Analisi Ambientale, IMAA-CNR, C. da S. Loya, Tito Scalo, Potenza (Italy)]. E-mail: serio@unibas.it; Bianchini, G. [Istituto di Fisica Applicata ' Nello Carrara' , IFAC-CNR, Via Panciatichi 64, Firenze (Italy); Palchetti, L. [Istituto di Fisica Applicata ' Nello Carrara' , IFAC-CNR, Via Panciatichi 64, Firenze (Italy); Pellegrini, M. [Istituto di Fisica Applicata ' Nello Carrara' , IFAC-CNR, Via Panciatichi 64, Firenze (Italy); Cuomo, V. [Istituto di Metodologie per l' Analisi Ambientale, IMAA-CNR, C. da S. Loya, Tito Scalo, Potenza (Italy); Masiello, G. [Istituto di Metodologie per l' Analisi Ambientale, IMAA-CNR, C. da S. Loya, Tito Scalo, Potenza (Italy); Pavese, G. [Istituto di Metodologie per l' Analisi Ambientale, IMAA-CNR, C. da S. Loya, Tito Scalo, Potenza (Italy)

    2007-02-15

    There is a growing interest in the far infrared spectral region 17-50 {mu}m as a remote sensing tool in atmospheric sciences, since this portion of the spectrum contains the characteristic molecular rotational band for water vapour. Much of the Earth energy lost to space is radiated through this spectral region. The Radiation Explorer in the Far InfraRed Breadboard (REFIR/BB) spectrometer was born because of the quest to make observations in the far infrared. REFIR/BB is a Fourier Transform Spectrometer with a sampling resolution of 0.5 cm{sup -1} and it was tested for the first time in the field to check its reliability and radiometric performance. The field campaign was held at Toppo di Castelgrande (40{sup o} 49' N, 15{sup o} 27' E, 1258 m a. s. l.), a mountain site in South Italy. The spectral and radiometric performance of the instrument and initial observations are shown in this paper. Comparisons to both (1) BOMEM MR100 Fourier Transform spectrometer observations and (2) line-by-line radiative transfer calculations for selected clear sky are presented and discussed. These comparisons (1) show a very nice agreement between radiance measured by REFIR/BB and by BOMEM MR100 and (2) demonstrate that REFIR/BB accurately observes the very fine spectral structure in the water vapour rotational band.

  13. Prototypic implementations of the building block for component based open Hypermedia systems (BB/CB-OHSs)

    DEFF Research Database (Denmark)

    Mohamed, Omer I. Eldai

    2005-01-01

    In this paper we describe the prototypic implementations of the BuildingBlock (BB/CB-OHSs) that proposed to address some of the Component-based Open Hypermedia Systems (CB-OHSs) issues, including distribution and interoperability [4, 11, 12]. Four service implementations were described below...

  14. Late Pleistocene-Holocene cataclysmic eruptions at Nevado de Toluca and Jocotitlan volcanoes, central Mexico

    Science.gov (United States)

    Macias, J.L.; Garcia, P.A.; Arce, J.L.; Siebe, C.; Espindola, J.M.; Komorowski, J.C.; Scott, K.

    1997-01-01

    This field guide describes a five day trip to examine deposits of Late Pleistocene-Holocene cataclysmic eruptions at Nevado de Toluca and Jocotitlan volcanoes in central Mexico. We will discuss the stratigraphy, petrology, and sedimentological characteristics of these deposits which provide insights into the eruptive history, type of volcanic activity, and transport and emplacement mechanisms of pyroclastic materials. These parameters will allow us to discuss the kinds of hazards and the risk that they pose to populations around these volcanoes. The area to be visited is tectonically complex thus we will also discuss the location of the volcanoes with respect to the tectonic environment. The first four days of the field trip will be dedicated to Nevado de Toluca Volcano (19 degrees 09'N; 99 degrees 45'W) located at 23 km. southwest of the City of Toluca, and is the fourth highest peak in the country, reaching an elevation of 4,680 meters above sea level (m.a.s.l.). Nevado de Toluca is an andesitic-dacitic stratovolcano, composed of a central vent excavated upon the remains of older craters destroyed by former events. Bloomfield and Valastro, (1974, 1977) concluded that the last cycle of activity occurred nearly equal 11,600 yr. ago. For this reason Nevado de Toluca has been considered an extinct volcano. Our studies, however, indicate that Nevado de Toluca has had at least two episodes of cone destruction by sector collapse as well as several explosive episodes including plinian eruptions and dome-destruction events. These eruptions occurred during the Pleistocene but a very young eruption characterized by surge and ash flows occurred ca. 3,300 yr. BP. This new knowledge of the volcano's eruptive history makes the evaluation of its present state of activity and the geological hazards necessary. This is important because the area is densely populated and large cities such as Toluca and Mexico are located in its proximity.

  15. La mort de Tupac Amaru, l’ultime cataclysme ?

    Directory of Open Access Journals (Sweden)

    Nejma Jalal-Kermele

    2011-06-01

    Full Text Available L’exécution du jeune Inca Tupac Amaru en 1572 fut pour les Indiens du Pérou un véritable cataclysme. Il s’insérait dans un contexte particulier : celui de la vice-royauté du Pérou qui connaissait, depuis de longues années, une série de guerres et de complots. Au cœur de cet espace troublé, se trouvait un royaume néo-inca que la Couronne espérait vaincre par une politique du compromis. Toledo, envoyé pour faire rentrer le Pérou dans un ordre nouveau, avait marqué, dès le début de son gouvernement, son opposition au régime de Vilcabamba dont la seule présence fragilisait la légitimité du pouvoir du roi de Castille aux Indes. C’était donc la question des Justes Titres qui préoccupait Toledo, décidé à lutter activement contre la pensée de Las Casas. La mort d’un messager, envoyé pour négocier avec l’Inca, servit de prétexte à une attaque de Vilcabamba qui permit l’arrestation du jeune Tupac Amaru que le vice-roi décida de condamner à mort, en dépit de sa conversion au catholicisme. L’exécution marqua pour les Indiens la fin d’un monde, la fin d’un espoir et apparut comme l’ultime catastrophe, une répétition de la mort de l’Inca et des Dieux. De nombreux récits rapportent la détresse infinie des Indiens et la désapprobation quasi générale des témoins. Nous voudrions proposer ici une rapide analyse des différentes lectures du cataclysme et tenter de montrer que, pour Toledo, il s’inséra dans une politique claire et assumée. Outre la question idéologique, le vice-roi s’appuya sur des arguments sécuritaires et fit finalement de Tupac Amaru non un prince mais un simple délinquant de droit commun. Cette réécriture de l’Histoire permit d’instaurer une nouvelle définition de la politique espagnole au Pérou mais le cataclysme marqua les esprits et Tupac Amaru, loin d’être oublié, devint un symbole qui traversa les siècles jusqu’à aujourd’hui.La ejecución del joven

  16. An Evaluation of Taiwanese B&B Service Quality Using the IPA Model

    Directory of Open Access Journals (Sweden)

    Gao-Liang Wang

    2012-09-01

    Full Text Available According to a December 2011 report released by Taiwan’s Tourism Bureau, there were 3,763 bed-and-breakfast guesthouses (B&B in Taiwan, 3,367 of which were legal with a combined 13,389 rooms, increasing by 96 percent from December 2006. It seems that the B&B sector is quite a popular target for investors. As the word-of-mouth advertising has been considered one of the most influential marketing methods, those who invest in B&Bs must manage to utilize their limited resources to improve customer satisfaction in a fast-growing and competitive market. The best marketing approach in reaching out to B&B customers, as suggested by this study’s author, would be word-of-mouth adverting. A PZB framed questionnaire is used in this study to explore the expectations and satisfaction of B&B customers both before and after the accommodation period, with the Importance-Performance Analysis (IPA model applied to analyze and measure the service quality. Findings from the questionnaire survey showed 3 out of the totally 23 service factors falling in the “concentrated concerned” quadrant (i.e., tidiness, architectural characteristics, and reasonable rates; 6 factors falling in the “continued maintenance” quadrant (i.e., adequate parking place, commitment to customers, handling of customers’ opinions, legality of B&B, grievance handling, and the local specialties-ordering service; 10 factors falling in the “low priority” quadrant (i.e., modern facilities, safety devices, availability of breakfast, security of online reservations; 4 factors falling in the “over-strived” quadrant (i.e., the availability of custom-made services, the ability to grasp customers’ needs, the availability of tour packages, and the availability of experiences regarding local industries.

  17. Elevated platelet-derived growth factor-BB concentrations in premature neonates who develop chronic lung disease

    Directory of Open Access Journals (Sweden)

    Adcock Kim G

    2004-06-01

    Full Text Available Abstract Background Chronic lung disease (CLD in the preterm newborn is associated with inflammation and fibrosis. Platelet-derived growth factor-BB (PDGF-BB, a potent chemotactic growth factor, may mediate the fibrotic component of CLD. The objectives of this study were to determine if tracheal aspirate (TA concentrations of PDGF-BB increase the first 2 weeks of life in premature neonates undergoing mechanical ventilation for respiratory distress syndrome (RDS, its relationship to the development of CLD, pulmonary hemorrhage (PH and its relationship to airway colonization with Ureaplasma urealyticum (Uu. Methods Infants with a birth weight less than 1500 grams who required mechanical ventilation for RDS were enrolled into this study with parental consent. Tracheal aspirates were collected daily during clinically indicated suctioning. Uu cultures were performed on TA collected in the first week of life. TA supernatants were assayed for PDGF-BB and secretory component of IgA concentrations using ELISA techniques. Results Fifty premature neonates were enrolled into the study. Twenty-eight infants were oxygen dependent at 28 days of life and 16 infants were oxygen dependent at 36 weeks postconceptual age. PDGF-BB concentrations peaked between 4 and 6 days of life. Maximum PDGF-BB concentrations were significantly higher in infants who developed CLD or died from respiratory failure. PH was associated with increased risk of CLD and was associated with higher PDGF-BB concentrations. There was no correlation between maximum PDGF-BB concentrations and Uu isolation from the airway. Conclusions PDGF-BB concentrations increase in TAs of infants who undergo mechanical ventilation for RDS during the first 2 weeks of life and maximal concentrations are greater in those infants who subsequently develop CLD. Elevation in lung PDGF-BB may play a role in the development of CLD.

  18. New Low Accretion-Rate Magnetic Binary Systems and their Significance for the Evolution of Cataclysmic Variables

    CERN Document Server

    Schmidt, G D; Vanlandingham, K M; Anderson, S F; Barentine, J C; Brewington, H J; Hall, P B; Harvanek, M; Kleinman, S J; Krzesínski, J; Long, D; Margon, B; Neilsen, E H; Newman, P R; Nitta, A; Schneider, D P; Snedden, S A

    2005-01-01

    Discoveries of two new white dwarf plus M star binaries with striking optical cyclotron emission features from the Sloan Digital Sky Survey (SDSS) brings to six the total number of X-ray faint, magnetic accretion binaries that accrete at rates 3 hr. Optical surveys for the cyclotron harmonics appear to be the only means of discovery, so the space density of pre-Polars could rival that of Polars, and the binaries provide an important channel of progenitors (in addition to the asynchronous Intermediate Polars). Both physical and SDSS observational selection effects are identified that may help to explain the clumping of all six systems in a narrow range of magnetic field strength around 60 MG.

  19. Perbandingan Granisetron 0,01 mg/KgBb dengan Ondansetron 0,08 Mg/Kg.Bb Untuk Mencegah Mual Muntah Pascaoperasi Dini Mastektomi Radikal Modifikasi

    Directory of Open Access Journals (Sweden)

    Budi Fitriyana

    2013-04-01

    Full Text Available Postoperative nausea and vomiting not only cause discomfort to the patient, but also lead to electrolyte imbalance, regurgitation and aspiration, bleeding and loss of surgical sutures. Patients who experience postoperative nausea and vomiting will require further attention and treatment which of course increases the cost of medical services. Women who underwent mastectomy with accompanying decision underarm lymph nodes have a high risk of postoperative nausea and vomiting. Many anti-vomiting are given including antihistamines, butyrophenon, and dopamine receptor antagonists have been reported to have undesirable side effects including excessive sedation, hypotension, dry mouth, dysphoria, hallucinations and extrapyramidal effects. 5 HT3 receptor antagonists provide a major advancement for treatment of postoperative nausea and vomiting due to fewer side effects when compared with anti-vomiting medications before. This study will compare the two drugs 5 HT3 receptor antagonist granisetron with ondansetron in preventing postoperative nausea and vomiting modified radical mastectomy early. Conducted research on 58 patients ASA I and II modified radical mastectomy is performed under general anesthesia. Sampling was carried out using double-blind randomized controlled trial. Samples were divided into two groups by block randomization. Group G is given granisetron 0.01 gr / kg.bb and group O is given ondansetron 0.08 mg / kg.bb. Drug treatment is administered intravenously 30 minutes before the surgery ended on a complete evaluation of blood pressure, heart rate, oxygen saturation and length of surgery. Postoperative nausea and vomiting shortly after surgery assessed every hour until 6 hours after surgery (early postoperative nausea and vomiting to 4 scale (0-3. Data were analyzed by t-test, Chi-square test, Mann-Whitney test and Fisher's Exact test on Windows SPSS ver.16 The results suggest there is a tendency complaints of postoperative nausea and

  20. Greenhouse-selected resistance to Cry3Bb1-producing corn in three western corn rootworm populations.

    Directory of Open Access Journals (Sweden)

    Lisa N Meihls

    Full Text Available Transgenic corn producing the Bacillus thuringiensis (Bt toxin Cry3Bb1 has been useful for controlling western corn rootworm, Diabrotica virgifera virgifera LeConte, one of the most economically important crop pests in the United States. However, rapid evolution of resistance by this beetle to Bt corn producing Cry3Bb1 has been reported previously from the laboratory, greenhouse, and field. Here we selected in the greenhouse for resistance to Cry3Bb1 corn in three colonies of WCR derived from Kansas, Minnesota, and Wisconsin, respectively. Three generations of rearing on Cry3Bb1 corn significantly increased larval survival on Cry3Bb1 corn, resulting in similar survival in the greenhouse for selected colonies on Cry3Bb1 corn and isoline corn that does not produce Bt toxin. After four to seven generations of rearing on Cry3Bb1 corn, survival in the field on Cry3Bb1 corn relative to isoline corn more than doubled for selected colonies (72% compared with control colonies (33%. For both selected and control colonies, survival in the field was significantly lower on Cry3Bb1 corn than on isoline corn. On isoline corn, most fitness components were similar for selected colonies and control colonies. However, fecundity was significantly lower for selected colonies than control colonies, indicating a fitness cost associated with resistance. The rapid evolution of resistance by western corn rootworm to Bt corn reported here and previously underlines the importance of effective resistance management for this pest.

  1. Covalently immobilized platelet-derived growth factor-BB promotes angiogenesis in biomimetic poly(ethylene glycol) hydrogels

    Science.gov (United States)

    Saik, Jennifer E.; Gould, Daniel J.; Watkins, Emily M.; Dickinson, Mary E.; West, Jennifer L.

    2011-01-01

    The field of tissue engineering is severely limited by a lack of microvascularization in tissue engineered constructs. Biomimetic poly(ethylene glycol) hydrogels containing covalently immobilized platelet-derived growth factor BB (PDGF-BB) were developed to promote angiogenesis. Poly(ethylene glycol) hydrogels resist protein absorption and subsequent non-specific cell adhesion, thus providing a “blank slate”, which can be modified through the incorporation of cell adhesive ligands and growth factors. PDGF-BB is a key angiogenic protein able to support neovessel stabilization by inducing functional anastomoses and recruiting pericytes. Due to the widespread effects of PDGF in the body and a half-life of only 30 min in circulating blood, immobilization of PDGF-BB may be necessary. In this work bioactive, covalently immobilized PDGF-BB was shown to induce tubulogenesis on two-dimensional modified surfaces, migration in three-dimensional (3D) degradable hydrogels and angiogenesis in a mouse cornea micro-pocket angiogenesis assay. Covalently immobilized PDGF-BB was also used in combination with covalently immobilized fibroblast growth factor-2, which led to significantly increased endothelial cell migration in 3D degradable hydrogels compared with the presentation of each factor alone. When a co-culture of endothelial cells and mouse pericyte precursor 10T1/2 cells was seeded onto modified surfaces tubule formation was independent of surface modifications with covalently immobilized growth factors. Furthermore, the combination of soluble PDGF-BB and immobilized PDGF-BB induced a more robust vascular response compared with soluble PDGF-BB alone when implanted into an in vivo mouse cornea micropocket angiogenesis assay. Based on these results, we believe bioactive hydrogels can be tailored to improve the formation of functional microvasculature for tissue engineering. PMID:20801242

  2. EFFECTS OF PDGF-BB ON INTRACELLULAR CALCIUM CONCENTRATION AND PROLIFERATION IN CULTURED GLOMERULAR MESANGIAL CELLS

    Institute of Scientific and Technical Information of China (English)

    WEN Li-ping; ZHANG Chong; BIAN Fan; ZOU Jun; JIANG Geng-ru; ZHU Han-wei

    2006-01-01

    Objective To investigate the relationship between the alteration of intracellular calcium concentration and proliferation in cultured glomerular mesangial cells. Methods Rat mesangial cells were cultured.Intracellular calcium concentrations were measured by confocal Laser Scanning Microscopy and Fura-3 fluorescence dyeing techniques. Cell growth was measured by MTT assay. Results PDGF-BB increased intracellular calcium concentrations in a dose-dependent manner, and at the same time promote the proliferation of mesangial cells. After preincubation with calcium channel blocker nifedipine or angiotensin converting enzyme inhibitor captopril, both the increase of intracellular calcium concentrations and cell proliferations induced by PDGF-BB were inhibited. Tripterigium Wilfordii Glycosides (TMG) significantly inhibited the mesangial cell proliferations, but it had no significant effect on intracellular calcium concentrations. Conclusion There was a positive relationship between the elevation of intracellular calcium concentration and cell proliferation in glomerular mesangial cells, but the increase of in- tracellular calcium concentrations wasn't the only way for proliferation.

  3. Iptakalim inhibits PDGF-BB-induced human airway smooth muscle cells proliferation and migration.

    Science.gov (United States)

    Liu, Wenrui; Kong, Hui; Zeng, Xiaoning; Wang, Jingjing; Wang, Zailiang; Yan, Xiaopei; Wang, Yanli; Xie, Weiping; Wang, Hong

    2015-08-15

    Chronic airway diseases are characterized by airway remodeling which is attributed partly to the proliferation and migration of airway smooth muscle cells (ASMCs). ATP-sensitive potassium (KATP) channels have been identified in ASMCs. Mount evidence has suggested that KATP channel openers can reduce airway hyperresponsiveness and alleviate airway remodeling. Opening K(+) channels triggers K(+) efflux, which leading to membrane hyperpolarization, preventing Ca(2+)entry through closing voltage-operated Ca(2+) channels. Intracellular Ca(2+) is the most important regulator of muscle contraction, cell proliferation and migration. K(+) efflux decreases Ca(2+) influx, which consequently influences ASMCs proliferation and migration. As a KATP channel opener, iptakalim (Ipt) has been reported to restrain the proliferation of pulmonary arterial smooth muscle cells (PASMCs) involved in vascular remodeling, while little is known about its impact on ASMCs. The present study was designed to investigate the effects of Ipt on human ASMCs and the mechanisms underlying. Results obtained from cell counting kit-8 (CCK-8), flow cytometry and 5-ethynyl-2'-deoxyuridine (EdU) incorporation showed that Ipt significantly inhibited platelet-derived growth factor (PDGF)-BB-induced ASMCs proliferation. ASMCs migration induced by PDGF-BB was also suppressed by Ipt in transwell migration and scratch assay. Besides, the phosphorylation of Ca(2+)/calmodulin-dependent kinase II (CaMKII), extracellular regulated protein kinases 1/2 (ERK1/2), protein kinase B (Akt), and cyclic adenosine monophosphate (cAMP) response element binding protein (CREB) were as well alleviated by Ipt administration. Furthermore, we found that the inhibition of Ipt on the PDGF-BB-induced proliferation and migration in human ASMCs was blocked by glibenclamide (Gli), a selective KATP channel antagonist. These findings provide a strong evidence to support that Ipt antagonize the proliferating and migrating effects of PDGF-BB on

  4. VUV Spectroscopic Study of the BB" 1Su+ State of H2

    CERN Document Server

    Dickenson, G D

    2013-01-01

    Spectral lines, probing rotational quantum states J'=0,1,2 of the inner well vibrations (v' =< 8) in the BB" 1Su+ state of molecular hydrogen, were recorded in high resolution using a vacuum ultraviolet (VUV) Fourier transform absorption spectrometer in the wavelength range 73-86 nm. Accurate line positions and predissociation widths are determined from a fit to the absorption spectra. Improved values for the line positions are obtained, while the predissociation widths agree well with previous investigations.

  5. B:b interactions are essential for polymerization of variant fibrinogens with impaired holes 'a'.

    Science.gov (United States)

    Okumura, N; Terasawa, F; Haneishi, A; Fujihara, N; Hirota-Kawadobora, M; Yamauchi, K; Ota, H; Lord, S T

    2007-12-01

    Fibrin polymerization is mediated by interactions between knobs 'A' and 'B' exposed by thrombin cleavage, and holes 'a' and 'b' always present in fibrinogen. The role of A:a interactions is well established, but the roles of knob:hole interactions A:b, B:b or B:a remain ambiguous. To determine whether A:b or B:b interactions have a role in thrombin-catalyzed polymerization, we examined a series of fibrinogen variants with substitutions altering holes 'a': gamma364Ala, gamma364His or gamma364Val. We examined thrombin- and reptilase-catalyzed fibrinopeptide release by high-performance liquid chromatography, fibrin clot formation by turbidity, fibrin clot structure by scanning electron microscopy (SEM) and factor (F) XIIIa-catalyzed crosslinking by sodium dodecylsulfate polyacrylamide gel electrophoresis. Thrombin-catalyzed fibrinopeptide A release was normal, but fibrinopeptide B release was delayed for all variants. The variant fibrinogens all showed markedly impaired thrombin-catalyzed polymerization; polymerization of gamma364Val and gamma364His were more delayed than gamma364Ala. There was absolutely no polymerization of any variant with reptilase, which exposed only knobs 'A'. SEM showed that the variant clots formed after 24 h had uniform, ordered fibers that were thicker than normal. Polymerization of the variant fibrinogens was inhibited dose-dependently by the addition of either Gly-Pro-Arg-Pro (GPRP) or Gly-His-Arg-Pro (GHRP), peptides that specifically block holes 'a' and 'b', respectively. FXIIIa-catalyzed crosslinking between gamma-chains was markedly delayed for all the variants. These results demonstrate that B:b interactions are critical for polymerization of variant fibrinogens with impaired holes 'a'. Based on these data, we propose a model wherein B:b interactions participate in protofibril formation.

  6. Prototypic implementations of the building block for component based open Hypermedia systems (BB/CB-OHSs)

    DEFF Research Database (Denmark)

    Mohamed, Omer I. Eldai

    2005-01-01

    In this paper we describe the prototypic implementations of the BuildingBlock (BB/CB-OHSs) that proposed to address some of the Component-based Open Hypermedia Systems (CB-OHSs) issues, including distribution and interoperability [4, 11, 12]. Four service implementations were described below. The....... These are the math service, navigational service, naming and location service and the storage service in addition to two communication protocols (TCP/IP and JAVA RMI)....

  7. Measure of the e+e-{yields}bb Cross Section at the LEP Energies; Medida de la seccion eficaz e''+e''-{yields}bb a las Energias de LEP

    Energy Technology Data Exchange (ETDEWEB)

    Arce Dubois, P.

    1992-07-01

    In the present work I analyse the data collected during 1990 by the L3 detector, situated in the electron-positron collider LEP. After selecting the events e''+e''-{yields} bb through their semileptonic decays into muons, I calculate the cross section for the process e''+e''- {yields} bb at different energy points around the mass of the vectorial boson Z, and I measure some parameters of the Standard Model, namely, the Br(b{yields}{mu} ),{gamma}{sub z}n-{yields}bb/{gamma}{sub z}n{yields}had and {gamma}{sub z}n{yields}bb{gamma}{sub z}n{yields}e''+e''-. (Author) 26 refs.

  8. SN 2009bb: a Peculiar Broad-Lined Type Ic Supernova

    CERN Document Server

    Pignata, Giuliano; Soderberg, Alicia; Mazzali, Paolo; Phillips, M M; Morrell, Nidia; Anderson, J P; Boldt, Luis; Campillay, Abdo; Contreras, Carlos; Folatelli, Gastón; Förster, Francisco; González, Sergio; Hamuy, Mario; Krzeminski, Wojtek; Maza, José; Roth, Miguel; Levesque, Francisco Salgado Emily M; Rest, Armin; Crain, J Adam; Foster, Andrew C; Haislip, Joshua B; Ivarsen, Kevin M; LaCluyze, Aaron P; Nysewander, Melissa C; Reichart, Daniel E

    2010-01-01

    Ultraviolet, optical, and near-infrared photometry and optical spectroscopy of the broad-lined Type Ic supernova (SN) 2009bb are presented, following the flux evolution from -10 to +285 days past B-band maximum. Thanks to the very early discovery, it is possible to place tight constraints on the SN explosion epoch. The expansion velocities measured from near maximum spectra are found to be only slightly smaller than those measured from spectra of the prototype broad-lined SN 1998bw associated with GRB 980425. Fitting an analytical model to the pseudo-bolometric light curve of SN 2009bb suggests that 4.1+-1.9 Msun of material was ejected with 0.22 +-0.06 Msun of it being 56Ni. The resulting kinetic energy is 1.8+-0.7x10^52 erg. This, together with an absolute peak magnitude of MB=-18.36+-0.44, places SN 2009bb on the energetic and luminous end of the broad-lined Type Ic (SN Ic) sequence. Detection of helium in the early time optical spectra accompanied with strong radio emission, and high metallicity of its en...

  9. Cordyceps sinensis polysaccharide inhibits PDGF-BB-induced inflammation and ROS production in human mesangial cells.

    Science.gov (United States)

    Wang, Ying; Wang, Yan; Liu, Dan; Wang, Wang; Zhao, Huan; Wang, Min; Yin, Hongping

    2015-07-10

    CPS-F, a polysaccharide derived from Cordyceps sinensis, is a potential anti-inflammatory and anti-oxidative agent. We demonstrated that CPS-F not only inhibits platelet-derived growth factor BB (PDGF-BB)-induced intracellular reactive oxygen species (ROS) generation, and up-regulation of tumor necrosis factor-α (TNF-α), TNF-α receptor 1 (TNFR1), and monocyte chemotactic protein-1 (MCP-1), but also acts synergistically in combination with MAPK/ERK inhibitor U0126 and PI3K/Akt inhibitor LY294002. Additionally, up-regulation of pro-inflammatory factors was reversed by use of a combination of CPS-F and NADPH oxidase (NOX) inhibitor diphenyleneiodonium chloride (DPI) or silencing of NOX1. Furthermore, CPS-F prevents the PDGF receptor β (PDGFRβ) promoter activity induced by PDGF-BB in transfected cells and ameliorates increased levels of TNF-α, TNFR1, and MCP-1 when PDGFRβ is silenced, thereby suggesting that CPS-F possesses a bidirectional regulatory function. Our findings suggest CPS-F may exert its therapeutic effect for the treatment of glomerulonephritis related to human mesangial cells (HMCs) through the ERK1/2/Akt pathways.

  10. Empigen BB: a useful detergent for solubilization and biochemical analysis of keratins.

    Science.gov (United States)

    Lowthert, L A; Ku, N O; Liao, J; Coulombe, P A; Omary, M B

    1995-01-05

    Intermediate filament (IF) proteins make up some of the most insoluble proteins known, and within the IF protein family, keratins are the least soluble. We compared the efficiency of nonionic, cationic, mixed nonionic and anionic, and zwitterionic detergents in solubilizing keratins from insect cells that express recombinant human keratins and from human colonic cell lines and normal keratinocytes. The cationic detergent cetyltrimethylammonium bromide was similar to the zwitterionic detergent Empigen BB in its ability to efficiently solubilize keratins, but the latter detergent was superior in that it maintained antibody reactivity and allowed for immunoprecipitation of the keratins. Although Nonidet-P40 partially solubilizes keratins, Empigen BB solubilizes a significant amount of keratins not solubilized by Nonidet-P40. In the case of vimentin, differences in solubilization efficiency among the detergents was not as dramatic as with keratins. Our results show that Empigen BB solubilizes a significant amount of epidermal and glandular keratins while preserving antigenicity. This detergent should prove useful for carrying out biochemical and molecular studies on these proteins and may be similarly beneficial for other IF proteins.

  11. Conserved Hypothetical BB0462 Protein Enhances the Transcription Activity of oppAⅤ Promoter%推定的BB0462蛋白增强oppAⅤ启动子的转录活性

    Institute of Scientific and Technical Information of China (English)

    王行国; 尹姣; 徐娴

    2006-01-01

    Borrelia burgdorferi基因组中BB0462 ORF编码一种由110个氨基酸组成的未知功能BB0462蛋白.使用推定的氨基酸序列在蛋白库中进行Blast比对以及推定蛋白的二级结构预测的结果都显示BB0462蛋白与YbaB家族的蛋白类似.共转化后β-半乳糖苷酶活性分析发现BB0462蛋白增强了B.burgdorferi lp54质粒携带的oppAⅤ上游调控区的转录活性,而对其他4个oppAⅠ~Ⅳ上游调控区调控区的转录活性没有影响.利用纯化的BB0462融合蛋白在体外分别与oppAⅠ~Ⅴ调控区DNA片段进行凝胶阻滞分析,发现BB0462蛋白仅与邻近oppAⅤ基因转录起始点的一段409 bp上游调控区DNA结合.用未标记的oppAⅤ上游调控区DNA与DIG-标记的oppAⅤ上游调控区DNA竞争BB0462蛋白,使凝胶上的DNA迁移阻滞带完全消失.β-半乳糖苷酶活性分析和凝胶阻滞分析表明BB0462蛋白在oppAⅤ基因表达的转录调控中可能起重要作用.

  12. Search for rare processes with a Z+bb signature at the LHC, with the matrix element method

    CERN Document Server

    Beluffi, Camille; Lemaitre, Vincent

    This thesis presents a detailed study of the final state with the Z boson decaying into two leptons, produced in the CMS detector at the LHC. In order to tag this topology, sophisticated b jet tagging algorithms have been used, and the calibration of one of them, the Jet Probability (JP) tagger is exposed. A study of the tagger degradation at high energy has been done and led to a small gain of performance. This investigation is followed by the search for the associated production of the standard model (SM) Higgs boson with a Z boson and decaying into two b quarks (ZH channel), using the Matrix Element Method (MEM) and two b-taggers: JP and Combined Secondary Vertex (CSV). The MEM is an advanced tool that produces an event-by-event discriminating variable, called weight. To apply it, several sets of transfer function have been produced. The final results give an observed limit on the ZH production cross section with the H → bb branching ratio of 5.46xσSM when using the CSV tagger and 4.89xσSM when using t...

  13. Assessment of fitness costs in Cry3Bb1 resistant and susceptible western corn rootworm (Coleoptera:Chrysomelidae) laboratory colonies

    Science.gov (United States)

    Maize production in the United States is dominated by plants genetically modified with transgenes from Bacillus thuringiensis (Bt). Varieties of Bt maize expressing Cry3Bb endotoxins that specifically target corn rootworms (genus Diabrotica) have proven highly efficacious. Howeve...

  14. Iptakalim inhibits PDGF-BB-induced human airway smooth muscle cells proliferation and migration

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Wenrui; Kong, Hui; Zeng, Xiaoning; Wang, Jingjing; Wang, Zailiang; Yan, Xiaopei; Wang, Yanli; Xie, Weiping, E-mail: wpxie@njmu.edu.cn; Wang, Hong, E-mail: hongwang@njmu.edu.cn

    2015-08-15

    Chronic airway diseases are characterized by airway remodeling which is attributed partly to the proliferation and migration of airway smooth muscle cells (ASMCs). ATP-sensitive potassium (K{sub ATP}) channels have been identified in ASMCs. Mount evidence has suggested that K{sub ATP} channel openers can reduce airway hyperresponsiveness and alleviate airway remodeling. Opening K{sup +} channels triggers K{sup +} efflux, which leading to membrane hyperpolarization, preventing Ca{sup 2+}entry through closing voltage-operated Ca{sup 2+} channels. Intracellular Ca{sup 2+} is the most important regulator of muscle contraction, cell proliferation and migration. K{sup +} efflux decreases Ca{sup 2+} influx, which consequently influences ASMCs proliferation and migration. As a K{sub ATP} channel opener, iptakalim (Ipt) has been reported to restrain the proliferation of pulmonary arterial smooth muscle cells (PASMCs) involved in vascular remodeling, while little is known about its impact on ASMCs. The present study was designed to investigate the effects of Ipt on human ASMCs and the mechanisms underlying. Results obtained from cell counting kit-8 (CCK-8), flow cytometry and 5-ethynyl-2′-deoxyuridine (EdU) incorporation showed that Ipt significantly inhibited platelet-derived growth factor (PDGF)-BB-induced ASMCs proliferation. ASMCs migration induced by PDGF-BB was also suppressed by Ipt in transwell migration and scratch assay. Besides, the phosphorylation of Ca{sup 2+}/calmodulin-dependent kinase II (CaMKII), extracellular regulated protein kinases 1/2 (ERK1/2), protein kinase B (Akt), and cyclic adenosine monophosphate (cAMP) response element binding protein (CREB) were as well alleviated by Ipt administration. Furthermore, we found that the inhibition of Ipt on the PDGF-BB-induced proliferation and migration in human ASMCs was blocked by glibenclamide (Gli), a selective K{sub ATP} channel antagonist. These findings provide a strong evidence to support that Ipt

  15. Safety of recombinant human platelet-derived growth factor-BB in Augment® Bone Graft

    Directory of Open Access Journals (Sweden)

    Luis A Solchaga

    2012-12-01

    Full Text Available This article discusses nonclinical and clinical data regarding the safety of recombinant human platelet-derived growth factor-BB as a component of the Augment® Bone Graft (Augment. Augment is a bone graft substitute intended to be used as an alternative to autologous bone graft in the fusion of hindfoot and ankle joints. Nonclinical studies included assessment of the pharmacokinetic profile of intravenously administered recombinant human platelet-derived growth factor-BB in rat and dog, effects of intravenous administration of recombinant human platelet-derived growth factor-BB in a reproductive and development toxicity study in rats, and chronic toxicity and carcinogenicity of Augment in a 12-month implantation model. These studies showed that systemic exposure was brief and clearance was rapid. No signs of toxicity, carcinogenicity, or tumor promotion were observed even with doses far exceeding the maximum clinical dose. Results of clinical trials (605 participants and commercial use of recombinant human platelet-derived growth factor-BB containing products indicate that these products are not associated with increased incidence of adverse events or cancer. The safety data presented provide evidence that recombinant human platelet-derived growth factor-BB is a safe therapeutic when used in combination products as a single administration during surgical procedures for bone repair and fusion. There is no evidence associating use of recombinant human platelet-derived growth factor-BB in Augment with chronic toxicity, carcinogenicity, or tumor promotion.

  16. Evaluation of Microcrystalline Chitosan and Fibrin Membranes as Platelet-Derived Growth Factor-BB Carriers with Amoxicillin

    Directory of Open Access Journals (Sweden)

    Kazimiera H. Bodek

    2015-01-01

    Full Text Available The aim of this study was to describe the mechanical and sorption features of homogeneous and composite membranes which consist of microcrystalline chitosan (MCCh and fibrin (Fb in various proportions as well as the in vitro kinetics of platelet-derived growth factor-BB (PDGF-BB released from ten types of membranes in the presence or absence of amoxicillin (Am. The films were characterized by Fourier transform infrared (FTIR spectroscopy, mechanical tests: breaking strength (Bs and elongation at break (Eb, as well as SEM images, and swelling study. The influence of the form of samples (dry or wet on Young’s modulus (E was also examined. The homogeneous MCCh (M1 and composite M3 and M4 (MCCh : Fb = 2 : 1 and 1 : 1 membranes were characterized by good sorption properties and higher mechanical strength, when compared with Fb (M2 membrane. Connecting MCCh with Fb decreases release of PDGF-BB and increases release of Am. The most efficient release of PDGF-BB was observed in the case of M4 (the optimum MCCh : Fb ratio was 1 : 1 membrane. It was found that the degree of PDGF-BB release from the membrane is influenced by the physicochemical and mechanical characteristics of the films and by its affinity to growth factor PDGF-BB.

  17. PDGF-BB-mediated activation of p42(MAPK) is independent of PDGF beta-receptor tyrosine phosphorylation.

    Science.gov (United States)

    Cartel, N J; Liu, J; Wang, J; Post, M

    2001-10-01

    Herein, we investigated the activity of mitogen-activated protein kinase (MAPK), a key component of downstream signaling events, which is activated subsequent to platelet-derived growth factor (PDGF)-BB stimulation. Specifically, p42(MAPK) activity peaked 60 min after addition of PDGF-BB, declined thereafter, and was determined not to be a direct or necessary component of glycosaminoglycan (GAG) synthesis. PDGF-BB also activated MAPK kinase 2 (MAPKK2) but had no effect on MAPKK1 and Raf-1 activity. Chemical inhibition of Janus kinase, phosphatidylinositol 3-kinase, Src kinase, or tyrosine phosphorylation inhibition of the PDGF beta-receptor (PDGFR-beta) did not abrogate PDGF-BB-induced p42(MAPK) activation or its threonine or tyrosine phosphorylation. A dominant negative cytoplasmic receptor for hyaluronan-mediated motility variant 4 (RHAMMv4), a regulator of MAPKK-MAPK interaction and activation, did not inhibit PDGF-BB-induced p42(MAPK) activation nor did a construct expressing PDGFR-beta with cytoplasmic tyrosines mutated to phenylalanine. However, overexpression of a dominant negative PDGFR-beta lacking the cytoplasmic signaling domain abrogated p42(MAPK) activity. These results suggest that PDGF-BB-mediated activation of p42(MAPK) requires the PDGFR-beta but is independent of its tyrosine phosphorylation.

  18. Deciphering IR Excess Observed by the Spitzer Space Telescope in Short Period Interacting Cataclysmic Binaries

    Science.gov (United States)

    Chun, Howard; Brinkworth, Carolyn; Ciardi, David; Hoard, Don; Howell, Steve; Stefaniak, Linda; Thomas, , Beth

    2006-03-01

    During the first year of the Spitzer Space Telescope Observing Program for Students and Teachers, our team observed a small sample of short orbital period interacting white dwarf binaries. Our scientific investigation was aimed at detection and characterization of the low mass, cool, brown dwarf-like mass donors in these systems. We used the Infrared Array Camera to obtain photometric observations of the polars EF Eri, GG Leo, V347 Pav, and RX J0154.0-5947 at 3.6, 4.5, 5.8, and 8.0 microns. In all our targets, we detected excess emission in the 3-8 micron region over that expected from a brown dwarf alone. One of the exciting discoveries we made with our IRAC observations is that the star EF Eri was found to be unexpectedly bright in the mid-IR (compared to its 2MASS magnitudes). This fact highlights an opportunity for us to observe EF Eri with the IRS as a follow-up proposal. EF Eri has a flux level of ~700 ?Jy at 8 microns. Thus, we are asking for time to obtain IRS data for only this star, our brightest source. We plan to obtain SL1 (7.4-14.5 microns) and SL2 (5.2-8.7 microns) spectroscopy only. We know the IRAC fluxes so our integration toies are well constrained and the spectral region covered by SL1, SL2 will yield sufficient S/N to differentiate between cool dust (rising BB like spectrum with PAH and other molecular features allowing us to determine dust size, temperature, and disk extent) and a T type dwarf showing characteristic spectral signatures and a falling Rayleigh-Jeans tail.

  19. Variable stars with the Kepler space telescope

    CERN Document Server

    Molnár, László; Plachy, Emese

    2016-01-01

    The Kepler space telescope has revolutionised our knowledge about exoplanets and stars and is continuing to do so in the K2 mission. The exquisite photometric precision, together with the long, uninterrupted observations opened up a new way to investigate the structure and evolution of stars. Asteroseismology, the study of stellar oscillations, allowed us to investigate solar-like stars and to peer into the insides of red giants and massive stars. But many discoveries have been made about classical variable stars too, ranging from pulsators like Cepheids and RR Lyraes to eclipsing binary stars and cataclysmic variables, and even supernovae. In this review, which is far from an exhaustive summary of all results obtained with Kepler, we collected some of the most interesting discoveries, and ponder on the role for amateur observers in this golden era of stellar astrophysics.

  20. Variable Star Network: World Center for Transient Object Astronomy and Variable Stars

    CERN Document Server

    Kato, T; Ishioka, R; Nogami, D; Kunjaya, C; Baba, H; Yamaoka, H

    2003-01-01

    Variable Star Network (VSNET, http://www.kusastro.kyoto-u.ac.jp/vsnet/) is a global professional-amateur network of researchers in variable stars and related objects, particularly in transient objects, such as cataclysmic variables, black hole binaries, supernovae and gamma-ray bursts. The VSNET has been playing a pioneering role in establishing the field of "transient object astronomy", by effectively incorporating modern advance in observational astronomy and global electronic network, as well as collaborative progress in theoretical astronomy and astronomical computing. The VSNET is now one of the best-featured global networks in this field of astronomy. We review on the historical progress, design concept, associated technology, and a wealth of scientific achievements powered by the VSNET.

  1. Search for Higgs boson pair production in the bb{sup -bar}bb{sup -bar} final state from pp collisions at √s=8 TeVwith the ATLAS detector

    Energy Technology Data Exchange (ETDEWEB)

    Aad, G. [CPPM, Aix-Marseille Université and CNRS/IN2P3, Marseille (France); Abbott, B. [Homer L. Dodge Department of Physics and Astronomy, University of Oklahoma, Norman, OK (United States); Abdallah, J. [Institute of Physics, Academia Sinica, Taipei, Taiwan (China); Abdinov, O. [Institute of Physics, Azerbaijan Academy of Sciences, Baku (Azerbaijan); Aben, R. [Nikhef National Institute for Subatomic Physics and University of Amsterdam, Amsterdam (Netherlands); and others

    2015-09-09

    A search for Higgs boson pair production pp→hh is performed with 19.5 fb{sup -1} of proton–proton collision data at √s=8 TeV, which were recorded by the ATLAS detector at the Large Hadron Collider in 2012. The decay products of each Higgs boson are reconstructed as a high-momentum bb{sup -bar} system with either a pair of small-radius jets or a single large-radius jet, the latter exploiting jet substructure techniques and associated b-tagged track-jets. No evidence for resonant or non-resonant Higgs boson pair production is observed. The data are interpreted in the context of the Randall–Sundrum model with a warped extra dimension as well as the two-Higgs-doublet model. An upper limit on the cross-section for pp→G{sub KK}{sup ∗}→hh→bb{sup -bar}bb{sup -bar} of 3.2 (2.3) fb is set for a Kaluza–Klein graviton G{sub KK}{sup ∗} mass of 1.0 (1.5) TeV, at the 95 % confidence level. The search for non-resonant Standard Model hh production sets an observed 95 % confidence level upper limit on the production cross-section σ(pp→hh→bb{sup -bar}bb{sup -bar}) of 202 fb, compared to a Standard Model prediction of σ(pp→hh→bb{sup -bar}bb{sup -bar})=3.6±0.5 fb.

  2. OpaR controls a network of downstream transcription factors in Vibrio parahaemolyticus BB22OP.

    Directory of Open Access Journals (Sweden)

    Alison Kernell Burke

    Full Text Available Vibrio parahaemolyticus is an emerging world-wide human pathogen that is associated with food-borne gastroenteritis when raw or undercooked seafood is consumed. Expression of virulence factors in this organism is modulated by the phenomenon known as quorum sensing, which permits differential gene regulation at low versus high cell density. The master regulator of quorum sensing in V. parahaemolyticus is OpaR. OpaR not only controls virulence factor gene expression, but also the colony and cellular morphology associated with growth on a surface and biofilm formation. Whole transcriptome Next Generation sequencing (RNA-Seq was utilized to determine the OpaR regulon by comparing strains BB22OP (opaR+, LM5312 and BB22TR (∆opaR1, LM5674. This work, using the published V. parahaemolyticus BB22OP genome sequence, confirms and expands upon a previous microarray analysis for these two strains that used an Affymetrix GeneChip designed from the closely related V. parahaemolyticus RIMD2210633 genome sequence. Overall there was excellent correlation between the microarray and RNA-Seq data. Eleven transcription factors under OpaR control were identified by both methods and further confirmed by quantitative reverse transcription PCR (qRT-PCR analysis. Nine of these transcription factors were demonstrated to be direct OpaR targets via in vitro electrophoretic mobility shift assays with purified hexahistidine-tagged OpaR. Identification of the direct and indirect targets of OpaR, including small RNAs, will enable the construction of a network map of regulatory interactions important for the switch between the nonpathogenic and pathogenic states.

  3. DMF inhibits PDGF-BB induced airway smooth muscle cell proliferation through induction of heme-oxygenase-1

    Directory of Open Access Journals (Sweden)

    Tamm Michael

    2010-10-01

    Full Text Available Abstract Background Airway wall remodelling is an important pathology of asthma. Growth factor induced airway smooth muscle cell (ASMC proliferation is thought to be the major cause of airway wall thickening in asthma. Earlier we reported that Dimethylfumarate (DMF inhibits platelet-derived growth factor (PDGF-BB induced mitogen and stress activated kinase (MSK-1 and CREB activity as well as IL-6 secretion by ASMC. In addition, DMF altered intracellular glutathione levels and thereby reduced proliferation of other cell types. Methods We investigated the effect of DMF on PDGF-BB induced ASMC proliferation, on mitogen activated protein kinase (MAPK activation; and on heme oxygenase (HO-1 expression. ASMC were pre-incubated for 1 hour with DMF and/or glutathione ethylester (GSH-OEt, SB203580, hemin, cobalt-protoporphyrin (CoPP, or siRNA specific to HO-1 before stimulation with PDGF-BB (10 ng/ml. Results PDGF-BB induced ASMC proliferation was inhibited in a dose-dependant manner by DMF. PDGF-BB induced the phosphorylation of ERK1/2 and p38 MAPK, but not of JNK. DMF enhanced the PDGF-BB induced phosphorylation of p38 MAPK and there by up-regulated the expression of HO-1. HO-1 induction inhibited the proliferative effect of PDGF-BB. HO-1 expression was reversed by GSH-OEt, or p38 MAPK inhibition, or HO-1 siRNA, which all reversed the anti-proliferative effect of DMF. Conclusion Our data indicate that DMF inhibits ASMC proliferation by reducing the intracellular GSH level with subsequent activation of p38 MAPK and induction of HO-1. Thus, DMF might reduce ASMC and airway remodelling processes in asthma.

  4. The role of dystroglycan in PDGF-BB-dependent migration of activated hepatic stellate cells/myofibroblasts

    Science.gov (United States)

    Kastanis, George John; Hernandez-Nazara, Zamira; Nieto, Natalia; Rincón-Sanchez, Ana Rosa; Popratiloff, Anastas; Dominguez-Rosales, Jose Alfredo; Lechuga, Carmen G.

    2011-01-01

    Hepatic stellate cells are embedded in the loose connective tissue matrix within the space of Disse. This extracellular matrix contains several basement membrane components including laminin, but its composition changes during liver injury because of the production of extracellular matrix components found in scar tissue. These changes in extracellular matrix composition and in cell-extracellular matrix interactions may play a key role in hepatic stellate cell transdifferentiation. In this communication we used early passages of mouse hepatic stellate cells (activated HSC/myofibroblasts) to study the platelet-derived growth factor BB (PDGF-BB)-dependent expression and regulation of β-dystroglycan and its role in activated HSC/myofibroblast migration. We used Northern and Western analysis to study dystroglycan expression and confocal microscopy to investigate changes in subcellular distribution of the protein. Activated HSC migration was investigated using an in vitro wound-healing assay. PDGF-BB induced significant changes in dystroglycan regulation and subcellular distribution of the protein. Whereas steady-state levels of dystroglycan mRNA remained constant, PDGF-BB increased dystroglycan transcription but shortened the t1/2 by 50%. Moreover, PDGF-BB changed dystroglycan and α5-integrin cellular distribution. Cell migration experiments revealed that PDGF-BB-dependent migration of activated HSC/myofibroblasts was completely blocked by neutralizing antibodies to fibronectin, α5-integrin, laminin, and β-dystroglycan. Overall, these findings suggest that both laminin and fibronectin and their receptors play a key role in PDGF-BB-induced activated HSC migration. PMID:21659621

  5. Application of platelet derived growth factor-BB and diabetic wound healing: the relationship with oxidative events.

    Science.gov (United States)

    Gökşen, Sibel; Balabanlı, Barbaros; Coşkun-Cevher, Şule

    2017-05-01

    The reasons that cause delay in wound healing in diabetes are a decrease in the level of growth factors secretion, an increase in the destruction of growth factors and in oxidative stress. Platelet derived growth factor (PDGF) is one of the important growth factors that play a role in all phases of wound healing. This study investigates time-dependent effects of topically PDGF-BB administration on oxidative events on the healing of dorsolateral-excisional wounds in diabetic rats. Forty-two female Wistar-albino rats with streptozotocin-induced diabetes were divided into four groups: control group, untreated group, chitosan-treated group, chitosan + PDGF-BB-treated group. Two identical full-thickness excisional skin wounds were made under anaesthesia in all rats except for the control group. In the PDGF-BB-treated and chitosan-treated groups, the wounds were treated topically PDGF-BB (7 ng/mL, single daily dose) and blank chitosan gel (equal amount) after wounding, respectively. After these administrations, on day 3 and day 7 of wound healing, rats were sacrificed. Thiobarbituric acid reactive substances, glutathione, nitric oxide, ascorbic acid levels, and superoxide dismutase activity in wound tissues were spectrophotometrically measured. PDGF-BB administration significantly increased TBARS levels and non-enzymatic antioxidant levels in early phase of diabetic wound healing. PDGF-BB dramatically reduced NOx levels on day 3 and sharply increased NOx levels on day 7 of wound healing. Consequently, PDGF-BB administration can be effective on oxidative balance in the early phase of diabetic wound healing.

  6. In vivo role of platelet-derived growth factor-BB in airway smooth muscle proliferation in mouse lung.

    Science.gov (United States)

    Hirota, Jeremy A; Ask, Kjetil; Farkas, Laszlo; Smith, Jane Ann; Ellis, Russ; Rodriguez-Lecompte, Juan Carlos; Kolb, Martin; Inman, Mark D

    2011-09-01

    Airway smooth muscle (ASM) hyperplasia in asthma likely contributes considerably to functional changes. Investigating the mechanisms behind proliferation of these cells may lead to therapeutic benefit. Platelet-derived growth factor (PDGF)-BB is a well known ASM mitogen in vitro but has yet to be directly explored using in vivo mouse models in the context of ASM proliferation and airway responsiveness. To determine the in vivo influence of PDGF-BB on gene transcripts encoding contractile proteins, ASM proliferation, and airway physiology, we used an adenovirus overexpression system and a model of chronic allergen exposure. We used adenovirus technology to selectively overexpress PDGF-BB in the airway epithelium of mice. Outcome measurements, including airway physiology, real time RT-PCR measurements, proliferating cell nuclear antigen staining, and airway smooth muscle quantification, were performed 7 days after exposure. The same outcome measurements were performed 24 hours and 4 weeks after a chronic allergen exposure model. PDGF-BB overexpression resulted in airway hyperresponsiveness, decreased lung compliance, increased airway smooth muscle cell numbers, positive proliferating cell nuclear antigen-stained airway smooth muscle cells, and a reduction in genes encoding contractile proteins. Chronic allergen exposure resulted in elevations in lung lavage PDGF-BB, which were observed in conjunction with changes in gene transcript expression encoding contractile proteins and ASM proliferation. We demonstrate for the first time in vivo that PDGF-BB induces ASM hyperplasia and changes in lung mechanics in mice and that, during periods of allergen exposure changes in lung, PDGF-BB are associated with changes in airway structure and function.

  7. Computerised emission and susceptibility MIL.STD testing with automated NB/BB detection

    Science.gov (United States)

    Vanessen, J. C.

    1990-09-01

    Automation of Electromagnetic Compatibility (EMC) testing is becoming common at many EMC test facilities. Commercial automated systems have become available in the past few years. The test and operations section has developed its own EMC automation to enhance and aid in testing. A complete overview of the automated EMC test facility in operation for emission and susceptibility measurements is presented. It includes a hardware description, the program structure and some of the methods required to complete such a program on the equipment chosen, including the Narrow Band (NB) and Broad Band (BB).

  8. XcJ Decays into B(B-) in Quark-Pair Creation Model

    Institute of Scientific and Technical Information of China (English)

    PING Rong-Gang; JIANG Huan-Qing

    2004-01-01

    A quark pair creation model is introduced to study the XcJ exclusive decays into baryon-antibaryon pairs.The decay widths for processes XcJ → BB- ( J = 0, 2; B = A, ∑0, E-) are evaluated phenomenologicaily with an explicit inclusion of the properties for outgoing baryons described by wave functions in the naive quark model. The results show that states XcJ (J = 0, 2) decay into A pair with a larger branching ratio than into p(p-) pair.

  9. Evidence for the H to bb decay in VH production with the ATLAS detector

    CERN Document Server

    CERN. Geneva

    2017-01-01

    Most Higgs bosons are expected to decay to a pair of b-quarks, with the Standard Model predicting a branching fraction of about 58%. Probing this decay is important to furthering our understanding of the Higgs sector, but its observation at hadron colliders is complicated by overwhelming Standard Model backgrounds. In this seminar, a search for the Higgs to bb decay, looking at the associated production of the Higgs boson with a W or Z boson, is presented using 36 fb-1 of 13 TeV LHC Run 2 data.

  10. Nanofibrous scaffolds incorporating PDGF-BB microspheres induce chemokine expression and tissue neogenesis in vivo.

    Directory of Open Access Journals (Sweden)

    Qiming Jin

    Full Text Available Platelet-derived growth factor (PDGF exerts multiple cellular effects that stimulate wound repair in multiple tissues. However, a major obstacle for its successful clinical application is the delivery system, which ultimately controls the in vivo release rate of PDGF. Polylactic-co-glycolic acid (PLGA microspheres (MS in nanofibrous scaffolds (NFS have been shown to control the release of rhPDGF-BB in vitro. In order to investigate the effects of rhPDGF-BB release from MS in NFS on gene expression and enhancement of soft tissue engineering, rhPDGF-BB was incorporated into differing molecular weight (MW polymeric MS. By controlling the MW of the MS over a range of 6.5 KDa-64 KDa, release rates of PDGF can be regulated over periods of weeks to months in vitro. The NFS-MS scaffolds were divided into multiple groups based on MS release characteristics and PDGF concentration ranging from 2.5-25.0 microg and evaluated in vivo in a soft tissue wound repair model in the dorsa of rats. At 3, 7, 14 and 21 days post-implantation, the scaffold implants were harvested followed by assessments of cell penetration, vasculogenesis and tissue neogenesis. Gene expression profiles using cDNA microarrays were performed on the PDGF-releasing NFS. The percentage of tissue invasion into MS-containing NFS at 7 days was higher in the PDGF groups when compared to controls. Blood vessel number in the HMW groups containing either 2.5 or 25 microg PDGF was increased above those of other groups at 7d (p<0.01. Results from cDNA array showed that PDGF strongly enhanced in vivo gene expression of the CXC chemokine family members such as CXCL1, CXCL2 and CXCL5. Thus, sustained release of rhPDGF-BB, controlled by slow-releasing MS associated with the NFS delivery system, enhanced cell migration and angiogenesis in vivo, and may be related to an induced expression of chemokine-related genes. This approach offers a technology to accurately control growth factor release to promote

  11. PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis.

    Science.gov (United States)

    Riedel, H; Yousaf, N; Zhao, Y; Dai, H; Deng, Y; Wang, J

    2000-01-06

    PSM/SH2-B has been described as a cellular partner of the FcepsilonRI receptor, insulin receptor (IR), insulin-like growth factor-I (IGF-I) receptor (IGF-IR), and nerve growth factor receptor (TrkA). A function has been proposed in neuronal differentiation and development but its role in other signaling pathways is still unclear. To further elucidate the physiologic role of PSM we have identified additional mitogenic receptor tyrosine kinases as putative PSM partners including platelet-derived growth factor (PDGF) receptor (PDGFR) beta, hepatocyte growth factor receptor (Met), and fibroblast growth factor receptor. We have mapped Y740 as a site of PDGFR beta that is involved in the association with PSM. We have further investigated the putative role of PSM in mitogenesis with three independent experimental strategies and found that all consistently suggested a role as a positive, stimulatory signaling adapter in normal NIH3T3 and baby hamster kidney fibroblasts. (1) PSM expression from cDNA using an ecdysone-regulated transient expression system stimulated PDGF-BB-, IGF-I-, and insulin- but not EGF-induced DNA synthesis in an ecdysone dose-responsive fashion; (2) Microinjection of the (dominant negative) PSM SH2 domain interfered with PDGF-BB- and insulin-induced DNA synthesis; and (3) A peptide mimetic of the PSM Pro-rich putative SH3 domain-binding region interfered with PDGF-BB-, IGF-I-, and insulin- but not with EGF-induced DNA synthesis in NIH3T3 fibroblasts. This experiment was based on cell-permeable fusion peptides with the Drosophila antennapedia homeodomain which effectively traverse the plasma membrane of cultured cells. These experimental strategies independently suggest that PSM functions as a positive, stimulatory, mitogenic signaling mediator in PDGF-BB, IGF-I, and insulin but not in EGF action. This function appears to involve the PSM SH2 domain as well as the Pro-rich putative SH3 domain binding region. Our findings support the model that PSM

  12. Sustained PDGF-BB release from PHBHHx loaded nanoparticles in 3D hydrogel/stem cell model.

    Science.gov (United States)

    Dong, Cui-Ling; Webb, William R; Peng, Qiang; Tang, James Z; Forsyth, Nicholas R; Chen, Guo-Qiang; El Haj, Alicia J

    2015-01-01

    This study aimed to design a growth factor loaded copolyester of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx) nanoparticles containing 3D collagen matrix to achieve growth factor sustained release for long-term stimulation of human mesenchymal stem cells (hMSCs) proliferation/differentiation for tissue engineer application. Platelet-derived growth factor-BB (PDGF-BB), which is known to enhance hMSCs proliferation in human serum, was selected as a model growth factor, and biodegradable copolyester of PHBHHx was chosen to be the sustained release vehicle. PDGF-BB phospholipid complex encapsulated PHBHHx nanoparticles were fabricated, and their effect on hMSCs proliferation was investigated via assays of CCK-8 and live-dead staining to cells inoculated in 2D tissue culture plates and 3D collagen gel scaffolds, respectively. The resulting spherical PHBHHx nanoparticles were stable in terms of their mean particle size, polydispersity index and zeta potential before and after lyophilization. In vitro study revealed a sustained release of PDGF-BB with a low burst release. Furthermore, sustained released PDGF-BB was revealed to significantly promote hMSCs proliferation in both cell monolayer and cell seeded 3D collagen scaffolds inoculated in serum-free media. Therefore, the 3D collagen matrices with locally sustained release growth factor nanoparticles hold promise to be used for stem cell tissue engineering.

  13. Effect of platelet-derived growth factor-BB on bone formation in calvarial defects: an experimental study in rabbits

    DEFF Research Database (Denmark)

    Vikjaer, D; Blom, S; Hjørting-Hansen, E

    1997-01-01

    with expanded polytetrafluoroethylene membranes to prevent interference with osteogenesis within the defect by the surrounding tissue and to keep the growth factor in place. A single dose of methylcellulose gel (4.4%) with (n = 8) or without rhPDGF-BB (50 micrograms/ml) (n = 8) was applied to the defects......, and the bone formation was evaluated after 8 weeks. Healing of defects in both groups was characterized by the presence of newly formed bone along the edges of the original defect and by a central area of fibrous connective tissue. The newly formed bone in the rhPDGF-BB treated defects had a trabecular...... of bone marrow was increased 75% in the rhPDGF-BB-treated defect. The porosity of cortical lamella in the newly formed bone was 84% higher in the rhPDGF-BB-treated defects compared to the control. These results show that administration of a single dose of rhPDGF-BB stimulates bone formation in critical...

  14. Excited state mass spectra of doubly heavy baryons {Ω _{cc}}, {Ω _{bb}}, and {Ω _{bc}}

    Science.gov (United States)

    Shah, Zalak; Thakkar, Kaushal; Rai, Ajay Kumar

    2016-10-01

    We discuss the mass spectrum of Ω baryon with two heavy quarks and one light quark ( ccs, bbs, and bcs). The main goal of the paper is to calculate the ground state masses and after that, the positive and negative parity excited states masses are also obtained within a hypercentral constituent quark model, using Coulomb plus linear potential framework. We also added a first order correction to the potential. The mass spectra up to 5S for radial excited states and 1P-5P, 1D-4D, and 1F-2F states for orbital excited states are computed for Ω _{cc}, Ω _{bb}, and Ω _{bc} baryons. Our obtained results are compared with other theoretical predictions, which could be a useful complementary tool for the interpretation of experimentally unknown heavy baryon spectra. The Regge trajectory is constructed in both the (n_r, M2) and the ( J, M2) planes for Ω _{cc}, Ω _{bb}, and Ω _{bc} baryons and their slopes and intercepts are also determined. Magnetic moments of doubly heavy Ω 's are also calculated.

  15. Hubble Space Telescope search for the transit of the Earth-mass exoplanet Alpha Centauri Bb

    CERN Document Server

    Demory, Brice-Olivier; Queloz, Didier; Seager, Sara; Gilliland, Ronald; Chaplin, William J; Proffitt, Charles; Gillon, Michael; Guenther, Maximilian N; Benneke, Bjoern; Dumusque, Xavier; Lovis, Christophe; Pepe, Francesco; Segransan, Damien; Triaud, Amaury; Udry, Stephane

    2015-01-01

    Results from exoplanet surveys indicate that small planets (super-Earth size and below) are abundant in our Galaxy. However, little is known about their interiors and atmospheres. There is therefore a need to find small planets transiting bright stars, which would enable a detailed characterisation of this population of objects. We present the results of a search for the transit of the Earth-mass exoplanet Alpha Centauri Bb with the Hubble Space Telescope (HST). We observed Alpha Centauri B twice in 2013 and 2014 for a total of 40 hours. We achieve a precision of 115 ppm per 6-s exposure time in a highly-saturated regime, which is found to be consistent across HST orbits. We rule out the transiting nature of Alpha Centauri Bb with the orbital parameters published in the literature at 96.6% confidence. We find in our data a single transit-like event that could be associated to another Earth-size planet in the system, on a longer period orbit. Our program demonstrates the ability of HST to obtain consistent, hi...

  16. Search for A to Zh(bb) in ATLAS at 13 TeV

    CERN Document Server

    Pandini, Carlo Enrico; The ATLAS collaboration

    2016-01-01

    A search for a heavy, CP-odd Higgs boson, A, decaying into a Z boson and a CP-even Higgs boson, h, with a mass of 125 GeV is performed using the ATLAS detector at the Large Hadron Collider. The search uses proton–proton collision data at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 3.2 /fb. Decays of h bosons to bb pairs, where the resulting hadronic jets can be resolved or are merged in the detector, are both considered. Final states of the Z boson decaying to a pair of charged leptons, Z → e+e− and Z → μ+μ−, or into neutrinos, Z → νν, are considered. The data are used to determine 95% confidence level upper limits on the product of production cross-sections and branching fractions, σ(pp → A)·BR(A → Zh)·BR(h → bb) for mA = [200,2000] GeV assuming gluon-fusion or b-quark-associated exclusive production. Results are also interpreted in the context of benchmark models for a two-Higgs doublet extension of the Standard Model.

  17. Implications of the partial width Z --> bb for supersymmetry searches and model-building

    CERN Document Server

    Wells, J D; Kane, G L; James D Wells; Chris Kolda

    1994-01-01

    Assuming that the actual values of the top quark mass at FNAL and of the ratio of partial widths Z->bb/Z->hadrons at LEP are within their current one-sigma reported ranges, we present a No-Lose Theorem for superpartner searches at LEP II and an upgraded Tevatron. We impose only two theoretical assumptions: the Lagrangian is that of the Minimal Supersymmetric Standard Model with arbitrary soft-breaking terms, and all couplings remain perturbative up to scales of order 10^16 GeV; there are no assumptions about the soft SUSY breaking parameters, proton decay, cosmology, etc. In particular, if the LEP and FNAL values hold up and supersymmetry is responsible for the discrepancy with the SM prediction of the partial width of Z->bb, then we must have charginos and/or top squarks observable at the upgraded machines. Furthermore, little deviation from the SM is predicted within "super-unified" SUSY. Finally, it appears to be extremely difficult to find any unified MSSM model, regardless of the form of soft SUSY breaki...

  18. Mitogenesis of Vascular Smooth Muscle Cell Stimulated by Platelet-Derived Growth Factor-bb Is Inhibited by Blocking of Intracellular Signaling by Epigallocatechin-3-O-Gallate

    Directory of Open Access Journals (Sweden)

    Mi Hee Lee

    2013-01-01

    Full Text Available Epigallocatechin gallate (EGCG is known to exhibit antioxidant, antiproliferative, and antithrombogenic effects and reduce the risk of cardiovascular diseases. Key events in the development of cardiovascular disease are hypertrophy and hyperplasia according to vascular smooth muscle cell proliferation. In this study, we investigated whether EGCG can interfere with PDGF-bb stimulated proliferation, cell cycle distribution, and the gelatinolytic activity of MMP and signal transduction pathways on RAOSMC when it was treated in two different ways—cotreatment with PDGF-bb and pretreatment of EGCG before addition of PDGF-bb. Both cotreated and pretreated EGCG significantly inhibited PDGF-bb induced proliferation, cell cycle progression of the G0/G1 phase, and the gelatinolytic activity of MMP-2/9 on RAOSMC. Also, EGCG blocked PDGF receptor-β (PDGFR-β phosphorylation on PDGF-bb stimulated RAOSMC under pretreatment with cells as well as cotreatment with PDGF-bb. The downstream signal transduction pathways of PDGFR-β, including p42/44 MAPK, p38 MAPK, and Akt phosphorylation, were also inhibited by EGCG in a pattern similar to PDGFR-β phosphorylation. These findings suggest that EGCG can inhibit PDGF-bb stimulated mitogenesis by indirectly and directly interrupting PDGF-bb signals and blocking the signaling pathway via PDGFR-β phosphorylation. Furthermore, EGCG may be used for treatment and prevention of cardiovascular disease through blocking of PDGF-bb signaling.

  19. The cellular proteome is affected by a gelsolin (BbGEL1) during morphological transitions in aerobic surface versus liquid growth in the entomopathogenic fungus Beauveria bassiana.

    Science.gov (United States)

    He, Pu-Hong; Dong, Wei-Xia; Chu, Xin-Ling; Feng, Ming-Guang; Ying, Sheng-Hua

    2016-11-01

    The gelsolin superfamily includes seven protein members: gelsolin, villin, adseverin, CapG, advillin, supervillin and flightless I. The gelsolin proteins are actin-binding proteins that contain three or six gelsolin-like domains, and they play important roles in remodelling actin dynamics and cellular processes in eukaryotes. The entomopathogenic fungus Beauveria bassiana expresses a unique CapG protein (BbGEL1) that contains three gelsolin-like domains. BbGEL1p is associated with actin during mycelial growth and plays an important role in fungal morphological transitions under both aerobic and submerged conditions. The ΔBbGEL1 mutant displays abnormal spore-producing structures that reduce the conidial and blastospore yields by approximately 70% and 90% respectively. The virulence of the ΔBbGEL1 mutant is notably reduced as indicated by topical and intrahemocoel injection assays. Two comparative proteomics analyses indicated that BbGEL1 has significantly different roles in the development of conidia and blastospores, and the results revealed the potential targets of BbGEL1 in the corresponding developmental processes. Additionally, as an overlapping downstream protein of BbGEL1, the hydrophobin-like protein gene BbHyd3 is required for conidiation but has a negative role in blastospore formation. Our findings indicate that in addition to its function as an actin-interacting protein, BbGEL1 contributes to fungal morphological transitions via broad genetic pathways.

  20. 4-1BB gene expression in peripheral blood mononuclear cells from orthotopic liver transplant recipients with graft acceptance

    Institute of Scientific and Technical Information of China (English)

    万云乐; 郑树森; 贾长库; 杨家印; 金晓凌; 赵志成

    2003-01-01

    Objective To investigate the gene expression of 4-1BB in peripheral blood mononuclear cells (PBMCs) and the possible significance of the 4-1BB pathway after clinical orthotopic liver transplantation (OLT). Methods 4-1BB mRNA levels in PBMCs from 22 OLT patients were analyzed by RT-PCR. 4-1BB protein expressed on the surface of CD4+ and CD8+ T cells were detected by flow cytometry, and visualized with direct immunofluorescence and confocal fluorescence microscopy. Patients with primary liver cancer (PLC) and healthy volunteers served as controls. Six cases of recently performed liver transplantation were also observed in this study.Results 4-1BB mRNA was detected in PBMCs from both liver transplant patients with long-term graft acceptance (22 cases) and from transplant patients on day 1 to day 3 post-transplantation (6 cases), but was not found in PBMCs from transplant patients on day 7 to day 30 post-transplantation (6 cases). 4-1BB mRNA was also not found in samples from 8 of the healthy controls and 7 of the PLC patients, though very low expression was detected in the other 4 healthy volunteers and 6 PLC patients. Simultaneously, 4-1BB protein was expressed at nearly undetectable levels on CD4+ and CD8+ T cells from healthy controls, PLC patients, as well as OLT patients within the first month post-transplantation (6 cases). However, 4-1BB expression was found on the surface of CD4+ and CD8+ T cells from liver transplant patients with long-term graft acceptance. Direct immunofluorescent staining and confocal fluorescence microscopy clearly revealed evidence of 4-1BB protein on cell membranes of CD4+ and CD8+ T cells from liver transplant patients with long-term graft acceptance. Simultaneously, a significantly higher percentage of CD3+ CD25+ T cells were found in liver transplant patients with long-term graft acceptance group as compared with the healthy control group (P<0.05). The expression of 4-1BB protein on T cells did not correlate with the survival

  1. Irradiated lymphocytes do not adoptively transfer diabetes or prevent spontaneous disease in the BB/W rat

    Energy Technology Data Exchange (ETDEWEB)

    Mordes, J.P.; Handler, E.S.; Like, A.A.; Nakano, K.; Rossini, A.A.

    1986-06-01

    Diabetes in the BB/W rat is autoimmune in origin, and lymphocytes from acutely diabetic animals activated by concanavalin A (con A) induce the disease in adoptive recipients. We report that irradiation of these cells prevents adoptive transfer of diabetes. Through 60 days of age, diabetes occurred in none of 47 BB/W rats given irradiated con A cells, but in 21 of 36 (58%) given nonirradiated cells. Between 60 and 130 days of age, however, spontaneous diabetes occurred in 18 of 34 untreated control rats (53%) and 16 of 32 rats (50%) given two injections of irradiated con A activated spleen cells. We conclude that irradiation prevents adoptive transfer of BB/W rat diabetes and that irradiated con A activated lymphocytes from acutely diabetic rats do not protect against spontaneous disease in susceptible recipients.

  2. A theoretical model of the tridimensional structure of Bacillus thuringiensis subsp. medellin Cry 11Bb toxin deduced by homology modelling

    Directory of Open Access Journals (Sweden)

    Gutierrez Pablo

    2001-01-01

    Full Text Available Cry11Bb is an insecticidal crystal protein produced by Bacillus thuringiensis subsp. medellin during its stationary phase; this ¶-endotoxin is active against dipteran insects and has great potential for mosquito borne disease control. Here, we report the first theoretical model of the tridimensional structure of a Cry11 toxin. The tridimensional structure of the Cry11Bb toxin was obtained by homology modelling on the structures of the Cry1Aa and Cry3Aa toxins. In this work we give a brief description of our model and hypothesize the residues of the Cry11Bb toxin that could be important in receptor recognition and pore formation. This model will serve as a starting point for the design of mutagenesis experiments aimed to the improvement of toxicity, and to provide a new tool for the elucidation of the mechanism of action of these mosquitocidal proteins.

  3. Bifidobacterium lactis Bb12 enhances intestinal antibody response in formula-fed infants: a randomized, double-blind, controlled trial.

    Science.gov (United States)

    Holscher, Hannah D; Czerkies, Laura A; Cekola, Pamela; Litov, Richard; Benbow, Marshall; Santema, Sheryl; Alexander, Dominik D; Perez, Vanessa; Sun, Shumei; Saavedra, José M; Tappenden, Kelly A

    2012-01-01

    Addition of probiotics to infant formula may positively affect immune function in nonexclusively breastfed infants. This study aimed to investigate the effect of infant starter formula containing the probiotic Bifidobacterium animalis subspecies lactis (Bb12) on intestinal immunity and inflammation. Six-week-old healthy, full-term infants (n = 172) were enrolled in a prospective, randomized, double-blind, controlled clinical trial with 2 groups studied in parallel to a breastfed comparison group. Formula-fed (FF) infants were randomized to partially hydrolyzed whey formula (CON) or the same formula containing 10(6) colony-forming units (CFU) Bb12/g (PRO) for 6 weeks. Fecal secretory IgA (sIgA), calprotectin, lactate, and stool pH were assessed at baseline, 2 weeks, and 6 weeks. Anti-poliovirus-specific IgA and anti-rotavirus-specific IgA were assessed at 2 and 6 weeks. Among vaginally delivered FF infants, PRO consumption increased (P IgA concentration increased (P IgA tended to increase (P = .056) with PRO consumption in cesarean-delivered infants. Anthropometrics and tolerance did not differ significantly between FF infants. Infants consuming formula with Bb12 produced feces with detectable presence of Bb12 and augmented sIgA concentration. Furthermore, cesarean-delivered infants consuming Bb12 had heightened immune response, as evidenced by increased anti-rotavirus- and anti-poliovirus-specific IgA following immunization. These results demonstrate that negative immune-related effects of not breastfeeding and cesarean delivery can be mitigated by including Bb12 in infant formula, thereby providing infants a safe, dietary, immune-modulating bacterial introduction.

  4. Heightened clinical utility of smartphone versus body-worn inertial system for shoulder function B-B score.

    Science.gov (United States)

    Pichonnaz, Claude; Aminian, Kamiar; Ancey, Céline; Jaccard, Hervé; Lécureux, Estelle; Duc, Cyntia; Farron, Alain; Jolles, Brigitte M; Gleeson, Nigel

    2017-01-01

    The B-B Score is a straightforward kinematic shoulder function score including only two movements (hand to the Back + lift hand as to change a Bulb) that demonstrated sound measurement properties for patients for various shoulder pathologies. However, the B-B Score results using a smartphone or a reference system have not yet been compared. Provided that the measurement properties are comparable, the use of a smartphone would offer substantial practical advantages. This study investigated the concurrent validity of a smartphone and a reference inertial system for the measurement of the kinematic shoulder function B-B Score. Sixty-five patients with shoulder conditions (with rotator cuff conditions, adhesive capsulitis and proximal humerus fracture) and 20 healthy participants were evaluated using a smartphone and a reference inertial system. Measurements were performed twice, alternating between two evaluators. The B-B Score differences between groups, differences between devices, relationship between devices, intra- and inter-evaluator reproducibility were analysed. The smartphone mean scores (SD) were 94.1 (11.1) for controls and 54.1 (18.3) for patients (P smartphone intra-evaluator ICC was 0.92, the bias 1.5 and the LOA -17.4 to 20.3. The smartphone inter-evaluator ICC was 0.92, the bias 1.5 and the LOA -16.9 to 20.0. The B-B Score results measured with a smartphone were comparable to those of an inertial system. While single measurements diverged in some cases, the intra- and inter-evaluator reproducibility was excellent and was equivalent between devices. The B-B score measured with a smartphone is straightforward and as efficient as a reference inertial system measurement.

  5. PD98059 Inhibited the Activation of Pancreatic Stellate Cells Mediated by Platelet-Derived Growth Factor BB in Rats

    Institute of Scientific and Technical Information of China (English)

    WAN Yuantai; WANG Tiancai; ZHAO Qiu

    2005-01-01

    Summary: To determine the biological effects of extracelluar signal regulated kinase (ERK) specific inhibitor PD98059 on pancreatic stellate cells (PSCs) activated by platelet-derived factor-BB (PDGF-BB), cultured rat PSCs were co-incubated at 37 ℃ for 24 h with 25 ng/ml PDGF-BB and different doses of PD98059 (ranging from 5 ng/ml to 40 ng/ml). Expression of pERK1 protein was detected by Western blot and collagen α1 (Ⅰ) mRNA was tested by reverse transcription-polymerase chain reaction (RT-PCR). Our results showed that there were statistical differences in the expression of pERK1 protein in all groups. Expression of pERK1 protein was up-regulated in the group treated by PDGF-BB, and gradually down-regulated in the other groups treated by PD98059 of different doses. An excellent positive correlation was revealed between the inhibitory effect and PD98059 concentrations. It was also observed that the expression of collagen α1 (Ⅰ) mRNA had similar response to pERK1. The level of collagen α1 (Ⅰ) mRNA was the highest in the PDGF-BB group, and gradually reduced in the other groups treated by PD98059 of different doses. It is concluded that expression of pERK1 protein and collagen α1 (Ⅰ) mRNA was up-regulated in rat PSCs activated by PDGF-BB. Meanwhile, PD98059 could inhibit PSCs activation mediated by PDGF. It is suggested that ERK1 protein plays an important role on PSCs activation mediated by PDGF signal pathway.

  6. Role of RhoA in platelet-derived growth factor-BB-induced migration of rat hepatic stellate cells

    Institute of Scientific and Technical Information of China (English)

    LI Lei; LI Jing; WANG Ji-yao; YANG Chang-qing; JIA Ming-lei; JIANG Wei

    2010-01-01

    Background Although the migration of hepatic stellate cells (HSCs) is essential for hepatic fibrotic response, the detailed mechanisms involved are poorly understood. The aim of this study was to examine the role of Rho GTPases (especially RhoA) in platelet-derived growth factor (PDGF)-BB-induced migration of HSCs.Methods The migration of primary rat HSCs was evaluated using transwell Boyden chamber, while cytoskeletal changes were visualized by immunofluorescence staining of intracellular actins and vinculin. Quantitative real-time PCR and Western blotting analysis were used to detect the expression of Rho GTPases (RhoA, Rac1 and Cdc42) within HSCs and their activation was determined by glutathione S-transferase pull-down assay. Finally, the effects of RhoA on PDGF-BB-induced cell migration and cytoskeletal remodeling were analyzed using HSC-T6 cells stably transfected with constitutively active (CA, Q63L) or dominant negative (DN, T19N) RhoA mutants. Data were analyzed using SPSS 16.0 software. Student's t test was used to analyze differences between two groups and one-way analysis of variance (ANOVA) was used among multiple groups.Results Rapid cytoskeletal remodeling led to a significant increase in the motility of primary rat HSCs after haptotactic (direct) and chemotactic (indirect) stimulation by PDGF-BB. PDGF-BB caused a dramatic elevation in the levels of both total and active RhoA protein. However, the levels of mRNA for Rho GTPases, including RhoA, Rac1 and Cdc42, were unaffected. Furthermore, PDGF-BB induced increased formation of stress fibers and focal adhesions in HSC-T6 cells transfected with CA-RhoA, but not in HSC-T6 transfected with DN-RhoA. Surprisingly, both CA- and DN-RhoA-transfected HSC-T6 cells showed decreased migratory potential in the absence or presence of PDGF-BB compared with controls.Conclusions PDGF-BB induced cytoskeletal remodeling in rat HSCs and promoted their migration via regulation of intracellular RhoA. RhoA may be one of

  7. Decomposition rates and residue-colonizing microbial communities of Bacillus thuringiensis insecticidal protein Cry3Bb-expressing (Bt) and non-Bt corn hybrids in the field.

    Science.gov (United States)

    Xue, Kai; Serohijos, Raquel C; Devare, Medha; Thies, Janice E

    2011-02-01

    Despite the rapid adoption of crops expressing the insecticidal Cry protein(s) from Bacillus thuringiensis (Bt), public concern continues to mount over the potential environmental impacts. Reduced residue decomposition rates and increased tissue lignin concentrations reported for some Bt corn hybrids have been highlighted recently as they may influence soil carbon dynamics. We assessed the effects of MON863 Bt corn, producing the Cry3Bb protein against the corn rootworm complex, on these aspects and associated decomposer communities by terminal restriction fragment length polymorphism (T-RFLP) analysis. Litterbags containing cobs, roots, or stalks plus leaves from Bt and unmodified corn with (non-Bt+I) or without (non-Bt) insecticide applied were placed on the soil surface and at a 10-cm depth in field plots planted with these crop treatments. The litterbags were recovered and analyzed after 3.5, 15.5, and 25 months. No significant effect of treatment (Bt, non-Bt, and non-Bt+I) was observed on initial tissue lignin concentrations, litter decomposition rate, or bacterial decomposer communities. The effect of treatment on fungal decomposer communities was minor, with only 1 of 16 comparisons yielding separation by treatment. Environmental factors (litterbag recovery year, litterbag placement, and plot history) led to significant differences for most measured variables. Combined, these results indicate that the differences detected were driven primarily by environmental factors rather than by any differences between the corn hybrids or the use of tefluthrin. We conclude that the Cry3Bb corn tested in this study is unlikely to affect carbon residence time or turnover in soils receiving these crop residues.

  8. Search for new resonances decaying to a W or Z boson and a Higgs boson in the ℓ+ℓ−bb¯, ℓνbb¯, and νν¯bb¯ channels with pp collisions at s=13 TeV with the ATLAS detector

    Directory of Open Access Journals (Sweden)

    M. Aaboud

    2017-02-01

    Full Text Available A search is presented for new resonances decaying to a W or Z boson and a Higgs boson in the ℓ+ℓ−bb¯, ℓνbb¯, and νν¯bb¯ channels in pp collisions at s=13 TeV with the ATLAS detector at the Large Hadron Collider using a total integrated luminosity of 3.2 fb−1. The search is conducted by looking for a localized excess in the WH/ZH invariant or transverse mass distribution. No significant excess is observed, and the results are interpreted in terms of constraints on a simplified model based on a phenomenological Lagrangian of heavy vector triplets.

  9. Optical Studies of Thirteen Hard X-ray Selected Cataclysmic Binaries from the Swift-BAT Survey

    CERN Document Server

    Halpern, J P

    2015-01-01

    From a set of thirteen cataclysmic binaries that were discovered in the Swift Burst Alert Telescope (BAT) survey, we conducted time-resolved optical spectroscopy and/or time-series photometry of eleven, with the goal of measuring their orbital periods and searching for spin periods. Seven of the objects in this study are new optical identifications. Orbital periods are found for seven targets, ranging from 81 minutes to 20.4 hours. PBC J0706.7+0327 is an AM Herculis star (polar) based on its emission-line variations and large amplitude photometric modulation on the same period. Swift J2341.0+7645 may be a polar, although the evidence here is less secure. Coherent pulsations are detected from two objects, Swift J0503.7-2819 (975 s) and Swift J0614.0+1709 (1412 s and 1530 s, spin and beat periods, respectively), indicating that they are probable intermediate polars (DQ Herculis stars). For two other stars, longer spin periods are tentatively suggested. We also present the discovery of a 2.00 hour X-ray modulati...

  10. The discovery and development of the BB rat colony: an animal model of spontaneous diabetes mellitus.

    Science.gov (United States)

    Chappel, C I; Chappel, W R

    1983-07-01

    The BB rat model of spontaneous diabetes mellitus was discovered in 1974 in Ottawa in a colony of specific pathogen-free Wistar rats. Investigations to determine the cause of rapid weight loss and death in a few weanling rats from this colony revealed polydypsia, polyuria, glucosuria, ketonuria, and hyperglycemia. These signs regressed and normal weight gain occurred when daily insulin therapy was given. Histologic studies of the pancreas of affected animals showed fibrosis and absence of beta cells. The original colony was established by crossbreeding the clinically normal parents of the diabetic animals. Approximately 10% of the offspring of these matings became diabetic. This incidence was increased to approximately 25% by father-daughter mating, suggesting a genetic component in the etiology.

  11. Production of haploids from anther culture of banana [Musa balbisiana (BB)].

    Science.gov (United States)

    Assani, A; Bakry, F; Kerbellec, F; Haïcour, R; Wenzel, G; Foroughi-Wehr, B

    2003-02-01

    We report here, for the first time, the production of haploid plants of banana Musa balbisiana (BB). Callus was induced from anthers in which the majority of the microspores were at the uninucleate stage. The frequency of callus induction was 77%. Callus proliferation usually preceded embryo formation. About 8% of the anthers developed androgenic embryos. Of the 147 plantlets obtained, 41 were haploids (n=x=11). The frequency of haploid production depended on genotypes used: 18 haploid plants were produced from genotype Pisang klutuk, 12 from Pisang batu, seven from Pisang klutuk wulung and four from Tani. The frequency of regeneration was 1.1%, which was based on the total number of anthers cultured. Diploid plants (2n=2x=22) were also observed in the regenerated plants. The haploid banana plants that were developed will be important material for the improvement of banana through breeding programmes.

  12. Microencapsulation and Fermentation of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12

    Directory of Open Access Journals (Sweden)

    Maryam Yari

    2015-09-01

    Full Text Available Because of poor survival of probiotic bacteria, microencapsulation evolved from the immobilized cell culture technology used in the biotechnological industry. Two probiotic strains, Bifidobacterium (BB-12 and Lactobacillus acidophilus (LA-5 were immobilized in calcium alginate by extrusion method. Encapsulation parameters and efficacy of this method were evaluated. Growth factors of these two bacteria were also measured by culturing in 10-L fermenter. Growth curves were obtained with respect to optical density and dry biomass weight. Encapsulation yield was over than 60% in each experiment. Scanning electron microscopy (SEM of Entrapment of cells in alginate matrix and cross-sections of dried bead were obtained and illustrated. Bifidobacterium have been shown better biotechnological properties.

  13. Search for the ttH (H → bb) process using the ATLAS detector

    Energy Technology Data Exchange (ETDEWEB)

    Asbah, Nedaa; Katzy, Judith; Keller, John [Deutsches Elektronen-Synchrotron (DESY) (Germany)

    2016-07-01

    The measurement of the Higgs boson production in association with top quarks (t anti tH) is an important goal of the LHC Run-II physics program as it allows a direct measurement of the top quark Yukawa coupling. In Run 1, this measurement suffered from a relatively low cross section at √(s) = 8 TeV and will benefit greatly from the higher luminosity and energy of Run II at √(s) = 13 TeV. A search for t anti tH production with the ATLAS detector at √(s) = 13 TeV ise presented. This study focuses on the search channel with the Higgs boson decaying to bb{sup -} and the tt{sup -} pair decaying semi-leptonically. A data-driven method for determining the background from events with mis-identified leptons has been developed.

  14. Thermostable levansucrase from Bacillus subtilis BB04, an isolate of Banana peel

    Directory of Open Access Journals (Sweden)

    Viniti D Vaidya

    2012-04-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Extensive screening resulted in the isolation of Bacillus sp. from Banana peel that produces considerable amount of thermostable levansucrase of molecular size 52kDa. 16S rRNA sequence analysis suggests that it belongs to Bacillus subtilis and was designated as strain BB04. Levansucrase was sucrose inducible, showed optimum activity at 50°C and pH 6.0. It was stable at pH range 6.0 - 7.0. Ca2+ at 1.0 mmol-1 concentration enhanced levansucrase activity by 24%. However levan production was highest at 40°C and pH 6.0. Cane molasses and juice proved to be good sources of sucrose for levan production. B. subtilis BB04 produced relatively more levan using cane molasses (11.32 gl-1 as sucrose source than in cane juice (4.81 gl-1.

  15. Assessment of commutability for candidate certified reference material ERM-BB130 "chloramphenicol in pork".

    Science.gov (United States)

    Zeleny, Reinhard; Emteborg, Håkan; Schimmel, Heinz

    2010-10-01

    Chloramphenicol (CAP), an effective antibiotic against many microorganisms, is meanwhile banned in the EU for treatment of food-producing animals due to adverse health effects. The Institute for Reference Materials and Measurements (IRMM) is currently developing a certified reference material (CRM) for CAP in pork, intended for validation and method performance verifications of analytical methods. The material will be certified using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and gas chromatography-mass spectrometry (GC-MS) methods and has a target CAP level around the minimum required performance limit (MRPL) of 0.3 microg/kg. To prove that the material can be applied as a quality control tool for screening methods, a commutability study was conducted, involving five commercially available enzyme-linked immunosorbent assay kits and one biosensor assay (BiaCore kit). Meat homogenates (cryo-milled wet tissue) with CAP concentrations around the MRPL and the candidate CRM (lyophilised powder) were measured by LC-MS/MS and GC-MS as well as the six screening methods. Pairwise method comparisons of results obtained for the two sample types showed that the CRM can successfully be applied as quality control (QC) sample to all six screening methods. The study suggests that ERM-BB130 is sufficiently commutable with the investigated assays and that laboratories applying one of the investigated kits therefore benefit from using ERM-BB130 to demonstrate the correctness of their results. However, differences among the assays were observed, either in the abundance of bias between screening and confirmatory LC and GC methods, the repeatability of test results, or goodness of fit between the methods.

  16. Growth factor PDGF-BB stimulates cultured cardiomyocytes to synthesize the extracellular matrix component hyaluronan.

    Directory of Open Access Journals (Sweden)

    Urban Hellman

    Full Text Available BACKGROUND: Hyaluronan (HA is a glycosaminoglycan located in the interstitial space which is essential for both structural and cell regulatory functions in connective tissue. We have previously shown that HA synthesis is up-regulated in a rat model of experimental cardiac hypertrophy and that cardiac tissue utilizes two different HA synthases in the hypertrophic process. Cardiomyocytes and fibroblasts are two major cell types in heart tissue. The fibroblasts are known to produce HA, but it has been unclear if cardiomyocytes share the same feature, and whether or not the different HA synthases are activated in the different cell types. METHODOLOGY/PRINCIPAL FINDINGS: This study shows, for the first time that cardiomyocytes can produce HA. Cardiomyocytes (HL-1 and fibroblasts (NIH 3T3 were cultivated in absence or presence of the growth factors FGF2, PDGF-BB and TGFB2. HA concentration was quantified by ELISA, and the size of HA was estimated using dynamic light scattering. Cardiomyocytes synthesized HA but only when stimulated by PDGF-BB, whereas fibroblasts synthesized HA without addition of growth factors as well as when stimulated by any of the three growth factors. When fibroblasts were stimulated by the growth factors, reverse dose dependence was observed, where the highest dose induced the least amount of HA. With the exception of TGFB2, a trend of reverse dose dependence of HA size was also observed. CONCLUSIONS/SIGNIFICANCE: Co-cultivation of cardiomyocytes and fibroblasts (80%/20% increased HA concentration far more that can be explained by HA synthesis by the two cell types separately, revealing a crosstalk between cardiomyocytes and fibroblasts that induces HA synthesis. We conclude that dynamic changes of the myocardium, such as in cardiac hypertrophy, do not depend on the cardiomyocyte alone, but are achieved when both cardiomyocytes and fibroblasts are present.

  17. 40 CFR 174.518 - Bacillus thuringiensis Cry3Bb1 protein in corn; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus thuringiensis Cry3Bb1 protein... PLANT-INCORPORATED PROTECTANTS Tolerances and Tolerance Exemptions § 174.518 Bacillus thuringiensis Cry3Bb1 protein in corn; exemption from the requirement of a tolerance. Residues of Bacillus...

  18. Crystallization and preliminary X-ray crystallographic study of the extracellular domain of the 4-1BB ligand, a member of the TNF family

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Jung-Sue; Kim, Dong-Uk [Department of Biology, Yonsei University, Seoul 120-749 (Korea, Republic of); Ahn, Byungchan; Kwon, Byoung Se [Immunomodulation Research Center, Ulsan University, Ulsan 680-749 (Korea, Republic of); Cho, Hyun-Soo, E-mail: hscho8@yonsei.ac.kr [Department of Biology, Yonsei University, Seoul 120-749 (Korea, Republic of)

    2006-01-01

    The extracellular domain of the 4-1BB ligand fused with glutathione-S-transferase was expressed in Escherichia coli (Origami) and purified by using affinity and ion-exchange column chromatographic methods. Crystals of the 4-1BB ligand were obtained at 290 K by the hanging-drop vapour-diffusion method. The 4-1BB ligand, a member of the tumour necrosis factor (TNF) family, is an important co-stimulatory molecule that plays a key role in the clonal expansion and survival of CD8+ T cells. Signalling through binding of the 4-1BB ligand and 4-1BB has been reported to enhance CD8+ T-cell expansion and protect activated CD8+ T cells from death. The 4-1BB ligand is an integral protein expressed on activated antigen-presenting cells. The extracellular domain of the 4-1BB ligand fused with glutathione-S-transferase was expressed in Escherichia coli (Origami) and purified by using affinity and ion-exchange column chromatographic methods. Crystals of the 4-1BB ligand were obtained at 290 K by the hanging-drop vapour-diffusion method. X-ray diffraction data were collected from these crystals to 2.8 Å resolution and the crystals belong to space group C2, with unit-cell parameters a = 114.6, b = 73.8, c = 118.50 Å, β = 115.5°.

  19. Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer, and cell-mediated immunity in the elderly.

    Science.gov (United States)

    Namba, Kazuyoshi; Hatano, Michiko; Yaeshima, Tomoko; Takase, Mitsunori; Suzuki, Kunihiko

    2010-01-01

    Twenty-seven elderly subjects (mean age 86.7+/-6.6 years) were pre-administered a test food containing 1x10(11) cfu of BB536 daily for 5 weeks (P1), during which they also received influenza vaccination at week 3. The subjects were then randomized to a BB536 group and a placebo group for 14 weeks (P2). The proportion of subjects who contracted influenza was significantly lower in BB536 group than in the to placebo group. The proportion of subjects with fever was also significantly lower in the BB536 group than in the placebo group. In the P1 period, the NK cell activity and the bactericidal activity of the neutrophils were significantly higher at week 5 than to before BB536 administration. In the P2 period, although NK cell activity and neutrophilic activities declined at the end of the study in both the placebo and the BB536 group, neutrophil phagocytic activity and NK cell activity tended to maintain slightly higher levels in the BB536 group than in the placebo group. These results suggest that continuous ingestion of BB536 reduces the incidence of influenza and fever, probably by potentiating innate immunity.

  20. Selection for Cry3Bb1 resistance in a genetically diverse population of nondiapausing Western Corn Rootworm (Coleoptera: Chrysomelidae)

    Science.gov (United States)

    Five short-diapause laboratory lines of western corn rootworm (Diabrotica virgifera virgifera) were selected for resistance to MON863, a variety of corn genetically modified with the Bacillus thuringiensis (Bt) transgene that expresses the Cry3Bb1 endotoxin. Three of the selecte...

  1. IL-1beta induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis

    DEFF Research Database (Denmark)

    Sparre, T; Bjerre-Christensen, Ulla; Mose Larsen, P;

    2002-01-01

    of 82 out of 1 815 protein spots detected by two dimensional gel electrophoresis in IL-1beta exposed diabetes prone Bio Breeding (BB-DP) rat islets of Langerhans in vitro. The aim of this study was to identify the proteins in these 82 spots by mass spectrometry and compare these changes with those seen...

  2. Finished Genome Sequence of Bacillus cereus Strain 03BB87, a Clinical Isolate with B. anthracis Virulence Genes.

    Science.gov (United States)

    Johnson, Shannon L; Minogue, Timothy D; Teshima, Hazuki; Davenport, Karen W; Shea, April A; Miner, Haven L; Wolcott, Mark J; Chain, Patrick S G

    2015-01-15

    Bacillus cereus strain 03BB87, a blood culture isolate, originated in a 56-year-old male muller operator with a fatal case of pneumonia in 2003. Here we present the finished genome sequence of that pathogen, including a 5.46-Mb chromosome and two plasmids (209 and 52 Kb, respectively).

  3. Greenhouse-selected resistance to Cry3Bb1-producing corn in three western corn rootworm populations

    Science.gov (United States)

    Transgenic corn producing the Bacillus thuringiensis (Bt) toxin Cry3Bb1 has been useful for controlling western corn rootworm, Diabrotica virgifera virgifera LeConte, one of the most economically important crop pests in the United States. However, rapid evolution of resistance by this beetle to Bt c...

  4. Bt-maize event MON 88017 expressing Cry3Bb1 does not cause harm to non-target organisms.

    Science.gov (United States)

    Devos, Yann; De Schrijver, Adinda; De Clercq, Patrick; Kiss, József; Romeis, Jörg

    2012-12-01

    This review paper explores whether the cultivation of the genetically modified Bt-maize transformation event MON 88017, expressing the insecticidal Cry3Bb1 protein against corn rootworms (Coleoptera: Chrysomelidae), causes adverse effects to non-target organisms (NTOs) and the ecological and anthropocentric functions they provide. Available data do not reveal adverse effects of Cry3Bb1 on various NTOs that are representative of potentially exposed taxonomic and functional groups, confirming that the insecticidal activity of the Cry3Bb1 protein is limited to species belonging to the coleopteran family of Chrysomelidae. The potential risk to non-target chrysomelid larvae ingesting maize MON 88017 pollen deposited on host plants is minimal, as their abundance in maize fields and the likelihood of encountering harmful amounts of pollen in and around maize MON 88017 fields are low. Non-target adult chrysomelids, which may occasionally feed on maize MON 88017 plants, are not expected to be affected due to the low activity of the Cry3Bb1 protein on adults. Impacts on NTOs caused by potential unintended changes in maize MON 88017 are not expected to occur, as no differences in composition, phenotypic characteristics and plant-NTO interactions were observed between maize MON 88017 and its near-isogenic line.

  5. Application of central composite design to optimize the amount of carbon source and prebiotics for Bifidobacterium bifidum BB01

    Directory of Open Access Journals (Sweden)

    Shu Guowei

    2016-06-01

    Full Text Available The objective of the present study was to obtain the optimum proportion of the carbon source and prebiotics for Bifidobacterium bifidum BB01 by the central composite design (CCD. The effect of carbon source (lactose and two prebiotics (inulin and fructooligosaccharides on the BB01 were observed by measuring the OD600 value, pH value and the viable counts at 18h. The final optimized concentrations of carbon source and prebiotics were: lactose 1.6%, inulin 0.26%, and fructooligosaccharides 0.22%. The result indicates that the growth of B. bifidum BB01 shows an significant increase in the optimized culture medium (p < 0.05, the OD600 value reached 1.434 at 18h, which increased 6.58% compared to the control. And the viable counts of B. bifidum BB01 increased 24.36% and reached (2.17±0.06 ×109cfu/mL. The results show that the optimization of the carbon source and prebiotics using CCD in this study is workable and necessary.

  6. Isolation of transcripts from Diabrotica virgifera virgifera LeConte responsive to the Bacillus thuringiensis toxin Cry3Bb1

    Science.gov (United States)

    Crystal proteins derived from Bacillus thuringiensis (Bt) have been widely used as a method of insect pest management for several decades. In recent years, a transgenic corn expressing the Cry3Bb1 toxin has been successfully used for protection against corn rootworm larvae (Genus...

  7. Influence of Bifidobacterium longum BB536 intake on faecal microbiota in individuals with Japanese cedar pollinosis during the pollen season.

    Science.gov (United States)

    Odamaki, Toshitaka; Xiao, Jin-Zhong; Iwabuchi, Noriyuki; Sakamoto, Mitsuo; Takahashi, Noritoshi; Kondo, Shizuki; Miyaji, Kazuhiro; Iwatsuki, Keiji; Togashi, Hideo; Enomoto, Tadao; Benno, Yoshimi

    2007-10-01

    It has been reported that intake of yogurt or powder supplemented with the Bifidobacterium longum BB536 probiotic strain alleviated subjective symptoms and affected blood markers of allergy in individuals with Japanese cedar pollinosis (JCPsis) during the pollen seasons of 2004 and 2005, based on randomized, double-blind, placebo-controlled trials. Furthermore, the 2004 study found that intestinal bacteria such as the Bacteroides fragilis group significantly fluctuated during the pollen season in JCPsis individuals and intake of BB536 yogurt tended to suppress these fluctuations. The present study investigated faecal microbiota to examine whether any changes occurred during the pollen season and whether any influence was exerted by intake of BB536 powder in the 2005 pollen season, which happened to be a heavy season, to confirm the 2004 findings and to evaluate the relationship of microbiota with symptom development. In a randomized, double-blind, placebo-controlled trial, 44 JCPsis subjects received BB536 or a placebo for 13 weeks during the pollen season. Another 14 Japanese cedar pollen (JCP)-specific IgE negative healthy subjects received placebo for the same period. Faecal samples were collected before (week 0), during (weeks 4, 8 and 13) and after (week 17) intervention, and out of JCP season (week 28). Faecal microbiota were analysed using terminal-RFLP (T-RFLP) and real-time PCR methods. Principal component analysis based on T-RFLP indicated distinct patterns of microbiota between healthy subjects and JCPsis subjects in the placebo group, but an intermediate pattern in the BB536 group at week 13, the last stage of the pollen season. The coordinate of principal component 1 at week 13 correlated with composite scores of JCPsis symptoms recorded during the pollen season. Faecalibacterium prausnitzii and the Bacteroides fragilis group were identified as the main contributors to microbiotal fluctuations. Real-time PCR indicated that BB536 intake suppressed

  8. Bifidobacterium animalis subsp. lactis BB-12 administration in early childhood: a randomized clinical trial of effects on oral colonization by mutans streptococci and the probiotic.

    Science.gov (United States)

    Taipale, T; Pienihäkkinen, K; Salminen, S; Jokela, J; Söderling, E

    2012-01-01

    A randomized clinical trial studied the effects of early administration of Bifidobacterium animalis subsp. lactis BB-12 (BB-12) on oral colonization of (1) mutans streptococci (MS), and (2) BB-12. In this double-blind, placebo-controlled study, infants (n = 106) received probiotic bacteria (BB-12 group), xylitol (X group), or sorbitol (S group). Test tablets were administered twice a day (from the age of 1-2 months) with a novel slow-release pacifier or a spoon (daily dose of BB-12 10(10) CFU, polyol 200-600 mg). Samples were collected from mucosa/teeth at the age of 8 months and 2 years for BB- 12 determination (qPCR) and plate culturing of MS (MSB, TYCSB), lactobacilli (Rogosa) and yeasts (Sabouraud). The MS levels of the mothers were determined (Dentocult SM Strip Mutans). The baseline characteristics of the three groups were similar. Mean duration of tablet delivery was 14.9 ± 6.7 months. In all groups, >90% of the mothers showed high MS counts (log CFU ≥5). MS colonization percentages of the children at the age of 2 years were rather low (BB-12 group: 6%; X group: 31%; S group: 10%; p < 0.05). The levels of lactobacilli and yeasts did not differ between the groups. BB-12 cell counts barely exceeding the detection limit were found in three of the oral samples of the 8-month-old children; however, the 2-year samples did not contain BB-12. The early administration of BB-12 did not result in permanent oral colonization of this probiotic or significantly affect MS colonization in the children.

  9. Regulation of a phenylalanine ammonia lyase (BbPAL) by calmodulin in response to environmental changes in the entomopathogenic fungus Beauveria bassiana.

    Science.gov (United States)

    Kim, Jiyoung; Park, Hyesung; Han, Jae-Gu; Oh, Junsang; Choi, Hyung-Kyoon; Kim, Seong Hwan; Sung, Gi-Ho

    2015-11-01

    Phenylalanine ammonia lyase (PAL, E.C. 4.3.1.5) catalyses the deamination of L -phenylalanine to trans-cinnamic acid and ammonia, facilitating a critical step in the phenylpropanoid pathway that produces a variety of secondary metabolites. In this study, we isolated BbPAL gene in the entomopathogenic fungus Beauveria bassiana. According to multiple sequence alignment, homology modelling and in vitro PAL activity, we demonstrated that BbPAL acts as a typical PAL enzyme in B. bassiana. BbPAL interacted with calmodulin (CaM) in vitro and in vivo, indicating that BbPAL is a novel CaM-binding protein. The functional role of CaM in BbPAL action was to negatively regulate the BbPAL activity in B. bassiana. High-performance liquid chromatography analysis revealed that L -phenylalanine was reduced and trans-cinnamic acid was increased in response to the CaM inhibitor W-7. Dark conditions suppressed BbPAL activity in B. bassiana, compared with light. In addition, heat and cold stresses inhibited BbPAL activity in B. bassiana. Interestingly, these negative effects of BbPAL activity by dark, heat and cold conditions were recovered by W-7 treatment, suggesting that the inhibitory mechanism is mediated through stimulation of CaM activity. Therefore, this work suggests that BbPAL plays a role in the phenylpropanoid pathway mediated by environmental stimuli via the CaM signalling pathway.

  10. 幽门螺杆菌重组Bb-hpaA-vacA疫苗的构建%Construction of recombinant Bb-hpaA-vacA vaccine of Helicobacter pylori

    Institute of Scientific and Technical Information of China (English)

    王国富; 高峰; 吴利先

    2012-01-01

    To construct the recombinant Bb hpaA vacA vaccine of Helicobacter pylori, hpaA and vacA antigen genes were amplified by PCR and the fusion gene hpaA vacA was obtained with gene SOEing. Then the fusion gene was cloned into Escherichia coli Bifidobacteria shuttle plasmid pGEX lλT to construct pGEX hpaA vacA. The recombinant plasmid was elec troporated into Bifidobacteria bifidum (Bb) to construct rBb hpaA vacA vaccine. The recombinant protein was analyzed by SDS PAGE. Its immunogenicity was identified by Western blotting. A 1500bp fusion gene of hpaA vacA was successfully am plified by PCR and cloned into pGEX 1λT by restriction analysis, and the rBb hpaA vacA vaccine was successfully constructed by PCR and restriction analysis. The recombinant protein could be expressed in B. Bifidium and it has immunogenicity. In this way, the rBb hpaA vacA vaccine of Helicobacter pylori is successfully constructed, which lays the experimental foundation of exploitation and utilization of this vaccine.%目的 构建幽门螵杆菌(Hp)重组双歧杆菌(Bb)Bb-hpaA-vacA疫苗.方法 通过PCR分别扩增hpaA和va-cA抗原编码基因,然后采用基因拼接法(gene SOEing)剪接hpaA和vacA,得到hpaA-vacA融合基因;将该融合基因定向克隆到大肠埃希菌-双歧杆菌穿梭表达载体pGEX-1λT,构建重组质粒pGEX-hpaA-vacA,电穿孔法将该质粒导入Bb,构建幽门螺杆菌重组hpaA-vacA疫苗,然后用SDS-PAGE和Western blotting鉴定表达的重组蛋白.结果 PCR成功扩增出分子量约为1500 bp的hpaA-vacA融合基因,双酶切证实hpaA-vacA融合基因成功插入pGEX-1λT中,并成功转化入双歧杆菌,而且重组蛋白能在双岐杆菌中得到正确表达,Western blotting显示重组蛋白具有免疫原性.结论成功构建螺杆菌rBb-hpaA-vacA疫苗,为该疫苗的进一步研究奠定了基础.

  11. Virulence of Spores and Fermentation Filtrates of Beauveria bassiana Bb-2%球孢白僵菌菌株Bb-2孢子侵染力和代谢产物毒力

    Institute of Scientific and Technical Information of China (English)

    高萍; 胡强; 王彭

    2012-01-01

    The virulence of Beauveria bassiana strain Bb-2 to Plutella xylostella and Myzus persicae was assayed by its alive spores and fermentation filtrates. The results showed that Bb—2 was highly virulent at three consistencies, 1.1×107,1.1×108, 1.1× 109 ind./mL. At high consistency l.l×109 ind./mL, the cumulative mortality of P. Xylostella was 75.0%; and of M. Persicae was 92.5% in 4 d. At low consistency, the cumulative mortality was 36.7%; and of M. Persicae was 47.7%. The fermentation filtrates of strain Bb-2 were also with anti-pest active; and the virulence against M. Persicae was stronger than P. Xylostells.%利用球孢白僵菌菌株Bb-2(Beauveria bassiana Bb-2)活体孢子和代谢产物对2龄小菜蛾(Plutella xylostella)幼虫和桃蚜(Myzus persicae)进行毒力测定.结果表明,菌株Bb-2在1.1×107、1.1×108、1.1×109个孢子/mL 3个浓度下,对2龄小菜蛾幼虫和桃蚜均表现出较高的侵染力.在高浓度(1.1×109个孢子/mL)条件下,2龄小菜蛾幼虫的4d累计死亡率为75.0%,桃蚜的4d累计死亡率为92.5%.在低浓度(1.1×107个孢子/mL)条件下,2龄小菜蛾幼虫的4d累计死亡率为36.7%,桃蚜的4d累计死亡率为47.7%.菌株Bb-2发酵液对2龄小菜蛾幼虫和桃蚜均有一定的活性,且对桃蚜的活性明显高于对小菜蛾的活性.

  12. Wind Variability in BZ Camelopardalis

    CERN Document Server

    Honeycutt, Kent; Robertson, Jeff

    2013-01-01

    (Shortened) Sequences of spectra of the nova-like cataclysmic variable (CV) BZ Cam were acquired on 9 nights in 2005-2006 in order to study the time development of episodes of wind activity known to occur frequently in this star. We confirm past results that the P-Cygni absorption components of the lines mostly evolve from a higher expansion velocity to lower velocity as an episode progresses. We also commonly find blueshifted emission components in the Halpha line profile, whose velocities and durations strongly suggest that they are also due to the wind. We suggest that the progression from larger to smaller expansion velocities is due the higher velocity portions of a wind concentration moving beyond the edge of the continuum light of the disk first, leaving a net redward shift of the remaining absorption profile. We also derive a new orbital ephemeris for BZ Cam, using the radial velocity of the core of the HeI 5876AA line, finding P = 0.15353(4). Using this period the wind episodes in BZ Cam are found to...

  13. Spontaneous autoimmune thyroiditis in Bio Breeding/Worcester (BB/W) rat.

    Science.gov (United States)

    Yanagisawa, M; Hara, Y; Satoh, K; Tanikawa, T; Sakatsume, Y; Katayama, S; Kawazu, S; Ishii, J; Komeda, K

    1986-12-01

    We investigated the serial changes in the plasma levels of anti-thyroglobulin antibody (ATA) by solid-phase enzyme immunoassay, thyroid hormones and blood glucose, since spontaneous occurring lymphocytic thyroiditis (LT) has been found in spontaneously diabetic Bio Breeding/Worcester (BB/W) rat. We also observed the correlation between these levels and histological findings in the thyroid gland. The incidence of diabetes was 0% in 5 week old rats (group A), 70% in 11 week old rats (group B), and 86% in 20 week old rats (group C), while LT was observed in 0% in group A, 20% in group B and 48% in group C. Although the incidence of both increased with age, there was no link between LT and diabetes. Plasma ATA levels were 91.4 +/- 28.5 (OD492 X 1,000, mean +/- SEM) in the control (14 week old Wistar Furth) rats. 49.5 +/- 15.4 in group A, 197.8 +/- 41.5 in group B, and 376.7 +/- 48.7 in group C, again showing a clear increase with age. In group C, the plasma levels of ATA in rats with LT were significantly higher than those without LT. In addition, 6 out of 11 rats without LT had abnormaly high ATA levels. In group C, the plasma levels of free 3,5,3'-triiodothyronine (FT3) and total thyroxine (TT4), and also the FT3/TT4 ratio were significantly lower and the plasma levels of blood glucose were higher than in the other groups. There was no difference between the plasma thyroid hormone levels in rats with LT and those without LT. These studies suggest that LT may occur independently of insulitis, namely diabetes, ATA levels and the incidence of LT increase with age, the site of ATA production may not be confined to the thyroid gland, and the derangement of glucose metabolism may be one of the factors in the decrease in plasma thyroid hormone. The BB/W rat is not only a useful animal model to use in exploring the pathogenesis of human insulin-dependent diabetes mellitus, but also spontaneous autoimmune thyroiditis.

  14. TRPM7 channel regulates PDGF-BB-induced proliferation of hepatic stellate cells via PI3K and ERK pathways

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Ling, E-mail: fangling_1984@126.com; Zhan, Shuxiang; Huang, Cheng; Cheng, Xi; Lv, Xiongwen; Si, Hongfang; Li, Jun, E-mail: lj@ahmu.edu.cn

    2013-11-01

    TRPM7, a non-selective cation channel of the TRP channel superfamily, is implicated in diverse physiological and pathological processes including cell proliferation. Recently, TRPM7 has been reported in hepatic stellate cells (HSCs). Here, we investigated the contribution role of TRPM7 in activated HSC-T6 cell (a rat hepatic stellate cell line) proliferation. TRPM7 mRNA and protein were measured by RT-PCR and Western blot in rat model of liver fibrosis in vivo and PDGF-BB-activated HSC-T6 cells in vitro. Both mRNA and protein of TRPM7 were dramatically increased in CCl{sub 4}-treated rat livers. Stimulation of HSC-T6 cells with PDGF-BB resulted in a time-dependent increase of TRPM7 mRNA and protein. However, PDGF-BB-induced HSC-T6 cell proliferation was inhibited by non-specific TRPM7 blocker 2-aminoethoxydiphenyl borate (2-APB) or synthetic siRNA targeting TRPM7, and this was accompanied by downregulation of cell cycle proteins, cyclin D1, PCNA and CDK4. Blockade of TRPM7 channels also attenuated PDGF-BB induced expression of myofibroblast markers as measured by the induction of α-SMA and Col1α1. Furthermore, the phosphorylation of ERK and AKT, associated with cell proliferation, decreased in TRPM7 deficient HSC-T6 cells. These observations suggested that TRPM7 channels contribute to perpetuated fibroblast activation and proliferation of PDGF-BB induced HSC-T6 cells via the activation of ERK and PI3K pathways. Therefore, TRPM7 may constitute a useful target for the treatment of liver fibrosis. - Highlights: • Upregulation of TRPM7 mRNA and protein in the fibrotic livers from CCl{sub 4}-treated rats. • Increasing expression of TRPM7 mRNA and protein during HSC activation. • Blockade of TRPM7 inhibited the PDGF-BB induced proliferation of HSC-T6 cells. • Blockade of TRPM7 decreased α-SMA and Col1α1 expressions in activated HSC-T6 cells. • TRPM7 up-regulation contributes to the activation of ERK and AKT pathways.

  15. Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor

    Energy Technology Data Exchange (ETDEWEB)

    Mochalkin, Igor; Knafels, John D.; Lightle, Sandra (Pfizer)

    2008-04-02

    The cell wall in Gram-negative bacteria is surrounded by an outer membrane comprised of charged lipopolysaccharide (LPS) molecules that prevent entry of hydrophobic agents into the cell and protect the bacterium from many antibiotics. The hydrophobic anchor of LPS is lipid A, the biosynthesis of which is essential for bacterial growth and viability. UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) is an essential zinc-dependant enzyme that catalyzes the conversion of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine to UDP-3-O-(R-3-hydroxymyristoyl)glucosamine and acetate in the biosynthesis of lipid A, and for this reason, LpxC is an attractive target for antibacterial drug discovery. Here we disclose a 1.9 A resolution crystal structure of LpxC from Pseudomonas aeruginosa (paLpxC) in a complex with the potent BB-78485 inhibitor. To our knowledge, this is the first crystal structure of LpxC with a small-molecule inhibitor that shows antibacterial activity against a wide range of Gram-negative pathogens. Accordingly, this structure can provide important information for lead optimization and rational design of the effective small-molecule LpxC inhibitors for successful treatment of Gram-negative infections.

  16. Decreased catecholamine secretion from the adrenal medullae of chronically diabetic BB-Wistar rats

    Science.gov (United States)

    Wilke, R. A.; Riley, D. A.; Lelkes, P. I.; Hillard, C. J.

    1993-01-01

    Many humans with IDDM eventually lose the capacity to secrete epinephrine from their adrenal medullae. The mechanism for this pathological change is unknown. We hypothesized that this abnormality is attributable to neuropathic changes in the greater splanchnic nerves or in the chromaffin cells that they innervate. To study this hypothesis, we isolated rat adrenal glands, perfused them ex vivo, and measured the epinephrine content of the perfusate under various conditions of stimulation. We used transmural electrical stimulation (20-80 V, at 10 Hz) to induce epinephrine secretion indirectly by selectively activating residual splanchnic nerve terminals within the isolated glands. Under these conditions, epinephrine secretion was severely attenuated in glands from female BB-Wistar rats with diabetes of 4 mo duration compared with their age-matched, nondiabetic controls. These perfused diabetic adrenal medullae also demonstrated decreased catecholamine release in response to direct chromaffin cell depolarization with 20 mM K+, evidence that a functional alteration exists within the chromaffin cells themselves. Nonetheless, total catecholamine content of adrenal medullae from these diabetic rats was not significantly different from controls, indicating that the secretory defect was not simply attributable to a difference in the amount of catecholamines stored and available for release. Herein, we also provide histological evidence of degenerative changes within the cholinergic nerve terminals that innervate these glands.

  17. Supercritical carbon dioxide interpolymer complexes improve survival of B. longum Bb-46 in simulated gastrointestinal fluids.

    Science.gov (United States)

    Thantsha, Mapitsi S; Cloete, Thomas E; Moolman, Francis S; Labuschagne, Philip W

    2009-01-31

    Gastric acidity is the main factor affecting viability of probiotics in the gastrointestinal tract (GIT). This study investigated the survival in simulated gastrointestinal fluids of Bifidobacterium longum Bb-46 encapsulated in interpolymer complexes formed in supercritical carbon dioxide (scCO(2)). Bacteria were exposed sequentially to simulated gastric fluid (SGF, pH 2) for 2 h and simulated intestinal fluid (SIF, pH 6.8) for 6 or 24 h. Total encapsulated bacteria were determined by suspending 1 g of product in SIF for 6 h at 37 degrees C prior to plating out. Plates were incubated anaerobically at 37 degrees C for 72 h. The interpolymer complex displayed pH-responsive release properties, with little to no release in SGF and substantial release in SIF. There was a limited reduction in viable counts at the end of exposure period due to encapsulation. Protection efficiency of the interpolymer complex was improved by addition of glyceryl monostearate (GMS). Gelatine capsules delayed release of bacteria from the interpolymer complex thus minimizing time of exposure to the detrimental conditions. Use of poly(caprolactone) (PCL), ethylene oxide-propylene oxide triblock copolymer (PEO-PPO-PEO) decreased the protection efficiency of the matrix. Interpolymer complex encapsulation showed potential for protection of probiotics and therefore for application in food and pharmaceuticals.

  18. First search for boosted Higgs boson production using the H->bb decay with CMS

    CERN Document Server

    CERN. Geneva

    2017-01-01

    An inclusive search for the standard model Higgs boson produced with high transverse momentum decaying to a bottom-antibottom quark pair has been performed using a data set of pp collisions at √s = 13 TeV collected with the CMS experiment at LHC. The data sample corresponds to an integrated luminosity of 35.9 fb−1. High-transverse-momentum Higgs bosons are reconstructed in a single jet with radius R = 0.8. Jet substructure and dedicated b-tagging techniques are used to identify boosted H → bb. The resulting experimental signature is a peak over a falling background in the distribution of the invariant mass of the jet. The Z process validates the analysis strategy and is observed with a local significance of 5.1 standard deviations for the first time in the single jet topology. An excess of events is observed above the expected background with a local significance of 1.3 standard deviations for a Higgs boson mass of 125 GeV. The signal strength corresponding to this excess, relative to that of the standa...

  19. (--Epigallocatechin Gallate Reduces Platelet-Derived Growth Factor-BB-Stimulated Interleukin-6 Synthesis in Osteoblasts: Suppression of SAPK/JNK

    Directory of Open Access Journals (Sweden)

    Osamu Kozawa

    2009-01-01

    Full Text Available We previously showed that the mitogen-activated protein (MAP kinase superfamily, p44/p42 MAP kinase, p38 MAP kinase, and stress-activated protein kinase (SAPK/c-Jun N-terminal (JNK, positively plays a part in the platelet-derived growth factor-BB- (PDGF-BB- stimulated synthesis of interleukin-6 (IL-6, a potent bone resorptive agent, in osteoblast-like MC3T3-E1 cells while Akt and p70 S6 kinase negatively regulates the synthesis. In the present study, we investigated whether (--epigallocatechin gallate (EGCG, one of the major green tea flavonoids, affects the synthesis of IL-6 in these cells and the mechanism. EGCG significantly reduced the IL-6 synthesis and IL-6 mRNA expression stimulated by PDGF-BB, EGCG reduced the PDGF-BB-stimulated IL-6 synthesis also in primary-cultured osteoblasts. EGCG had no effect on the levels of osteocalcin and osteoprotegerin in MC3T3-E1 cells. The PDGF-BB-induced autophosphorylation of PDGF receptor β was not suppressed by EGCG. The PDGF-BB-induced phosphorylation of p44/p42 MAP kinase and p38 MAP kinase was not affected by EGCG. On the other hand, EGCG markedly suppressed the PDGF-BB-induced phosphorylation of SAPK/JNK. Finally, the PDGF-BB-induced phosphorylation of Akt and p70 S6 kinase was not affected by EGCG. These results strongly suggest that EGCG inhibits the PDGF-BB-stimulated synthesis of IL-6 via suppression of SAPK/JNK pathway in osteoblasts.

  20. Safety of Bifidobacterium animalis subsp. lactis (B. lactis) strain BB-12-supplemented yogurt in healthy adults on antibiotics: a phase I safety study.

    Science.gov (United States)

    Merenstein, Daniel J; Tan, Tina P; Molokin, Aleksey; Smith, Keisha Herbin; Roberts, Robert F; Shara, Nawar M; Mete, Mihriye; Sanders, Mary Ellen; Solano-Aguilar, Gloria

    2015-01-01

    Probiotics are live microorganisms that, when administered in sufficient doses, provide health benefits on the host. The United States Food and Drug Administration (FDA) requires phase I safety studies for probiotics when the intended use of the product is as a drug. The purpose of the study was to determine the safety of Bifidobacterium animalis subsp lactis (B. lactis) strain BB-12 (BB-12)-supplemented yogurt when consumed by a generally healthy group of adults who were prescribed a 10-day course of antibiotics for a respiratory infection. Secondary aims were to assess the ability of BB-12 to affect the expression of whole blood immune markers associated with cell activation and inflammatory response. A phase I, double-blinded, randomized controlled study was conducted in compliance with FDA guidelines for an Investigational New Drug (IND). Forty participants were randomly assigned to consume 4 ounces of either BB-12 -supplemented yogurt or non-supplemented control yogurt daily for 10 d. The primary outcome was to assess safety and tolerability, assessed by the number of reported adverse events. A total of 165 non-serious adverse events were reported, with no differences between the control and BB-12 groups. When compared to the control group, B lactis fecal levels were modestly higher in the BB-12-supplemented group. In a small subset of patients, changes in whole blood expression of genes associated with regulation and activation of immune cells were detected in the BB-12-supplemented group. BB-12-supplemented yogurt is safe and well tolerated when consumed by healthy adults concurrently taking antibiotics. This study will form the basis for future randomized clinical trials investigating the potential immunomodulatory effects of BB-12-supplemented yogurt in a variety of disease states.

  1. C.P.Bourg推出Bourg BB3202全自动无线胶订机

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    drupa2012上,C.P.Bourg展出了与数码印刷机进行连线生产的新一代BourgBB3202全自动无线胶订机。新型BourgBB3202可以装订很厚的合订本,能够生产的产品包括单黑的手册、用户指南,到全彩色的目录、族谱、照片书等,其最大加工速度为350本/小时。生产的图书幅面从100mm×100mm到385mm×320mm,厚度为1~60mm。

  2. A nutritious medida (Sudanese cereal thin porridge) prepared by fermenting malted brown rice flour with Bifidobacterium longum BB 536.

    Science.gov (United States)

    Kabier, Barka M; Mustafa, Suhaimi; Kharidah, Muhammad; Suraini, Abd-Aziz; Abdul Manap, Yazid

    2004-09-01

    The nutritive value of spontaneously fermented brown rice flour medida, a Sudanese cereal thin porridge, is low. This study was carried out to improve the nutritional quality of medida. The flour was soaked and malted at 30◦C to optimise the protein content. Flour malted for two days had the highest protein content. Skim milk was added to the malted brown rice flour medida and fermented using Bifidobacterium longum BB 536. Maximum count of B. longum BB 536 up to 9 log CFU/ ml was attained at 4.6 final fermentation pH. The resultant viscosity was similar to that of the spontaneously fermented brown rice flour medida. There was significant (Pmedida have stable flowing characteristics and meet the whole protein and energy requirements for infants and children aged 1 - 10 years old.

  3. Advanced Manufacturing Process for Lower Cost Rechargeable Lithium-ion Batteries for DOD Including the BB2590

    Science.gov (United States)

    2013-11-30

    Nickelate in 18650 Cell 24 8. Installation of Resistance Welder 25 9. Bi-Cell Vacuum Dryer and with Activation Box 26 10. Semi...DOD lithium-ion rechargeable cells/batteries are composed of combinations using Asian 18650 cells including the BB2590. This dependence is due to the...much lower cost of the Asian and particularly the Chinese 18650 cells which are made on very large scale and also with lower labor costs. LithChem

  4. The neonatal levels of TSB, NSE and CK-BB in autism spectrum disorder from Southern China

    Directory of Open Access Journals (Sweden)

    Lv Meng-na

    2016-01-01

    Full Text Available Background" Autism spectrum disorder (ASD is a serious neurodevelopmental disorder that impairs a child’s ability to communicate with others. It also includes restricted repetitive behaviors, interests and activities. Symptoms manifest before the age of 3. In the previous studies, we found structural abnormalities of the temporal lobe cortex. High spine densities were most commonly found in ASD subjects with lower levels of cognitive functioning. In the present study, we retrospectively analyzed medical records in relation to the neonatal levels of total serum bilirubin (TSB, neuron-specific enolase (NSE, creatine kinase brain band isoenzyme (CK-BB, and neonatal behavior in ASD patients from Southern China. Methods: A total of 80 patients with ASD (ASD group were screened for this retrospective study. Among them, 34 were low-functioning ASD (L-ASD group and 46 were high-functioning ASD (H-ASD group. Identification of the ASD cases was confirmed with a Revised Autism Diagnostic Inventory. For comparison with ASD cases, 80 normal neonates (control group were selected from the same period. Biochemical parameters, including TSB, NSE and CK-BB in the neonatal period and medical records on neonatal behavior were collected. Results: The levels of serum TSB, NSE and CK-BB in the ASD group were significantly higher when compared with those from the control group (P 0.05 in the ASD group. Conclusions: The neonatal levels of TSB, NSE and CK-BB in ASD from Southern China were significantly higher than those of healthy controls. These findings need to be investigated thoroughly by future studies with large sample.

  5. Pulsed estrogen therapy prevents post-OVX porcine dura mater microvascular network weakening via a PDGF-BB-dependent mechanism.

    Directory of Open Access Journals (Sweden)

    Olga V Glinskii

    Full Text Available In postmenopausal women, estrogen (E2 deficiencies are frequently associated with higher risk of intracranial hemorrhage, increased incidence of stroke, cerebral aneurysm, and decline in cognitive abilities. In younger postpartum women and those using oral contraceptives, perturbations in E2 are associated with higher risk of cerebral venous thrombosis. A number of serious intracranial pathologic conditions linked to E2 deficiencies, such as dural sinus thrombosis, dural fistulae, non-parenchymal intracranial hemorrhages, migraines, and spontaneous cerebrospinal fluid leaks, involve the vessels not of the brain itself, but of the outer fibrous membrane of the brain, the dura mater (DM. The pathogenesis of these disorders remains mysterious and how estrogen regulates structural and functional integrity of DM vasculature is largely unknown. Here, we demonstrate that post ovariectomy (OVX DM vascular remodeling is manifested by microvessel destabilization, capillary rarefaction, increased vascular permeability, and aberrant angio-architecture, and is the result of disrupted E2-regulated PDGF-BB signaling within dura microvasculature. These changes, associated with the reduction in systemic PDGF-BB levels, are not corrected by a flat-dose E2 hormone replacement therapy (HRT, but are largely prevented using HRT schedules mimicking physiological E2 fluctuations. We demonstrate that 1 E2 regulates PDGF-BB production by endothelial cells in a dose-dependent manner and 2 optimization of PDGF-BB levels and induction of robust PDGF-mediated endothelial cell-vascular pericyte interactions require high (estrous E2 concentrations. We conclude that high (estrous levels of E2 are important in controlling PDGF-mediated crosstalk between endothelial cells and pericytes, a fundamental mechanism governing microvessel stability and essential for preserving intracranial homeostasis.

  6. Pulsed Estrogen Therapy Prevents Post-OVX Porcine Dura Mater Microvascular Network Weakening via a PDGF-BB-Dependent Mechanism

    Science.gov (United States)

    Glinskii, Olga V.; Huxley, Virginia H.; Glinskii, Vladimir V.; Rubin, Leona J.; Glinsky, Vladislav V.

    2013-01-01

    In postmenopausal women, estrogen (E2) deficiencies are frequently associated with higher risk of intracranial hemorrhage, increased incidence of stroke, cerebral aneurysm, and decline in cognitive abilities. In younger postpartum women and those using oral contraceptives, perturbations in E2 are associated with higher risk of cerebral venous thrombosis. A number of serious intracranial pathologic conditions linked to E2 deficiencies, such as dural sinus thrombosis, dural fistulae, non-parenchymal intracranial hemorrhages, migraines, and spontaneous cerebrospinal fluid leaks, involve the vessels not of the brain itself, but of the outer fibrous membrane of the brain, the dura mater (DM). The pathogenesis of these disorders remains mysterious and how estrogen regulates structural and functional integrity of DM vasculature is largely unknown. Here, we demonstrate that post ovariectomy (OVX) DM vascular remodeling is manifested by microvessel destabilization, capillary rarefaction, increased vascular permeability, and aberrant angio-architecture, and is the result of disrupted E2-regulated PDGF-BB signaling within dura microvasculature. These changes, associated with the reduction in systemic PDGF-BB levels, are not corrected by a flat-dose E2 hormone replacement therapy (HRT), but are largely prevented using HRT schedules mimicking physiological E2 fluctuations. We demonstrate that 1) E2 regulates PDGF-BB production by endothelial cells in a dose-dependent manner and 2) optimization of PDGF-BB levels and induction of robust PDGF-mediated endothelial cell-vascular pericyte interactions require high (estrous) E2 concentrations. We conclude that high (estrous) levels of E2 are important in controlling PDGF-mediated crosstalk between endothelial cells and pericytes, a fundamental mechanism governing microvessel stability and essential for preserving intracranial homeostasis. PMID:24349391

  7. BDTs in the Search for ttH Production
with Higgs Decays to bb at ATLAS

    CERN Document Server

    Glaysher, Paul; The ATLAS collaboration

    2017-01-01

    An observation of Higgs boson production in association with a top quark pair (ttH) provides a direct measurement of the top quark Yukawa coupling and probes the Standard Model. The ATLAS search for ttH->bb relies on Boosted Decision Trees for Higgs reconstruction and signal-background discrimination. 
Higgs boson decays to two bottom quarks, and top pair decays with one or two leptons are considered.

  8. Optimized QKD BB84 protocol using quantum dense coding and CNOT gates: feasibility based on probabilistic optical devices

    Science.gov (United States)

    Gueddana, Amor; Attia, Moez; Chatta, Rihab

    2014-05-01

    In this work, we simulate a fiber-based Quantum Key Distribution Protocol (QKDP) BB84 working at the telecoms wavelength 1550 nm with taking into consideration an optimized attack strategy. We consider in our work a quantum channel composed by probabilistic Single Photon Source (SPS), single mode optical Fiber and quantum detector with high efficiency. We show the advantages of using the Quantum Dots (QD) embedded in micro-cavity compared to the Heralded Single Photon Sources (HSPS). Second, we show that Eve is always getting some information depending on the mean photon number per pulse of the used SPS and therefore, we propose an optimized version of the QKDP BB84 based on Quantum Dense Coding (QDC) that could be implemented by quantum CNOT gates. We evaluate the success probability of implementing the optimized QKDP BB84 when using nowadays probabilistic quantum optical devices for circuit realization. We use for our modeling an abstract probabilistic model of a CNOT gate based on linear optical components and having a success probability of sqrt (4/27), we take into consideration the best SPSs realizations, namely the QD and the HSPS, generating a single photon per pulse with a success probability of 0.73 and 0.37, respectively. We show that the protocol is totally secure against attacks but could be correctly implemented only with a success probability of few percent.

  9. Search for the SM and MSSM Higgs boson in the ttH, H-->bb channel

    CERN Document Server

    Richter-Was, Elzbieta

    1998-01-01

    A detailes study of the associated Standard Model Higgs boson production ttH with H-->bb is presented for the SM and MSSM scenarios. For the Higgs boson masses from 80 to 120 GeV and an integrated luminosity of 3 10^4 pb^-1 a clear evidence for an excess of events with four b-tagged jets over the background from W+jets and tt production should be observable. However, a clean reconstruc tion of the H-->bb mass peak will be difficult because of the combinatorial bgd from the signal itself. This problem can be to large extent overcome if both top-quark decays are reconstructed in addition to the reconstruction of the H-->bb mass peak. In the MSSM scenario, the low tanb region (up to tanb ~ 6) for an integrated luminosity of 3 10^4 pb^-1 and most of the (mA, tanb) parame ter space for an integrated luminosity of 10^5 pb^-1 would be accesible with this channel. Excellent b-tagging capability and good efficiency for jet recons truction are however necessary to explore this channel to its full potential.

  10. Hybrid CATV/MMW/BB lightwave transmission system based on fiber-wired/fiber-wireless/fiber-VLLC integrations.

    Science.gov (United States)

    Li, Chung-Yi; Lu, Hai-Han; Lu, Ting-Chieh; Chu, Chien-An; Chen, Bo-Rui; Lin, Chun-Yu; Peng, Peng-Chun

    2015-12-14

    A hybrid lightwave transmission system for cable television (CATV)/millimeter-wave (MMW)/baseband (BB) signal transmission based on fiber-wired/fiber-wireless/fiber-visible laser light communication (VLLC) integrations is proposed and demonstrated. For down-link transmission, the light is intensity-modulated with 50-550 MHz CATV signal and optically promoted from 25 GHz radio frequency (RF) signal to 10 Gbps/50 GHz and 20 Gbps/100 GHz MMW data signals based on fiber-wired and fiber-wireless integrations. Good performances of carrier-to-noise ratio (CNR), composite second-order (CSO), composite triple-beat (CTB), and bit error rate (BER) are obtained over a 40-km single-mode fiber (SMF) and a 10-m RF wireless transport. For up-link transmission, the light is successfully intensity-remodulated with 5-Gbps BB data stream based on fiber-VLLC integration. Good BER performance is achieved over a 40-km SMF and a 10-m free-space VLLC transport. Such a hybrid CATV/MMW/BB lightwave transmission system is an attractive alternative, it gives the benefits of a communication link for broader bandwidth and higher transmission rate.

  11. Vibrational Spectral Signatures of Crystalline Cellulose Using High Resolution Broadband Sum Frequency Generation Vibrational Spectroscopy (HR-BB-SFG-VS)

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Libing; Lu, Zhou; Velarde Ruiz Esparza, Luis A.; Fu, Li; Pu, Yunqiao; Ding, Shi-You; Ragauskas, Art J.; Wang, Hongfei; Yang, Bin

    2015-03-03

    Here we reported the first sub-wavenumber high-resolution broadband sum frequency generation vibrational spectroscopy (HR-BB-SFG-VS) study on both the C-H and O-H region spectra of crystalline cellulose. HR-BB-SFG-VS has about 10 times better resolution than the conventional scanning SFG-VS and is known to be able to measure the intrinsic spectral lineshape and to resolve much more spectral details. With HR-BB-SFG-VS, we found that in cellulose from different sources, including Avicel and cellulose crystals isolated from algae Valonia (Iα) and tunicates (Iβ), the spectral signatures in the OH regions were unique for different allomorphs, i.e. Iα and Iβ, while the spectral signatures in the C-H regions varied in all samples examined. Even though the origin of the different behaviors of the crystalline cellulose in the O-H and C-H vibrational frequency regions is yet to be correlated to the structure of cellulose, these results provided new spectroscopic methods and opportunities to classify and understand the basic crystalline structure, as well as variations, in polymorphism of the crystalline cellulose structure.

  12. FRAGMENT Bb: EVIDENCE FOR ACTIVATION OF THE ALTERNATIVE PATHWAY OF THE COMPLEMENT SYSTEM IN PREGNANT WOMEN WITH ACUTE PYELONEPHRITIS

    Science.gov (United States)

    Soto, Eleazar; Romero, Roberto; Vaisbuch, Edi; Erez, Offer; Mazaki-Tovi, Shali; Kusanovic, Juan Pedro; Dong, Zhong; Chaiworapongsa, Tinnakorn; Yeo, Lami; Mittal, Pooja; Hassan, Sonia S.

    2010-01-01

    OBJECTIVE Pyelonephritis during pregnancy is associated with a more severe course than in the non-pregnant state. This has been attributed to an increased susceptibility of pregnant women to microbial products. The complement system is part of innate immunity and its alternative pathway is activated mainly by microorganisms. The purpose of this study was to determine if activation of the alternative pathway of the complement system (determined by maternal fragment Bb concentrations) occurs in pregnant women with acute pyelonephritis. METHODS This cross-sectional study included the following groups: 1) normal pregnant women (n=62); and 2) pregnant women with pyelonephritis (n=38). Maternal plasma Fragment Bb concentrations were determined by ELISA. Non-parametric statistics were used for analyses. RESULTS 1) Pregnant women with pyelonephritis had a higher median plasma concentration of fragment Bb than those with a normal pregnancy (1.3 μg/ml, IQR: 1.1-1.9 vs. 0.8 μg/m, IQR: 0.7-0.9; ppyelonephritis who had a positive blood culture and those with a negative blood culture (1.4 μg/ml, IQR: 1.1-3.5 vs. 1.3 μg/ml, IQR: 1.1-1.9; p=0.2). CONCLUSIONS Pregnant women with acute pyelonephritis have evidence of activation of the alternative pathway of the complement system, regardless of the presence or absence of a positive blood culture. PMID:20218820

  13. BB0347, from the lyme disease spirochete Borrelia burgdorferi, is surface exposed and interacts with the CS1 heparin-binding domain of human fibronectin.

    Directory of Open Access Journals (Sweden)

    Robert A Gaultney

    Full Text Available The causative agent of Lyme disease, Borrelia burgdorferi, codes for several known fibronectin-binding proteins. Fibronectin a common the target of diverse bacterial pathogens, and has been shown to be essential in allowing for the development of certain disease states. Another borrelial protein, BB0347, has sequence similarity with these other known fibronectin-binding proteins, and may be important in Lyme disease pathogenesis. Herein, we perform an initial characterization of BB0347 via the use of molecular and biochemical techniques. We found that BB0347 is expressed, produced, and presented on the outer surface of intact B. burgdorferi. We also demonstrate that BB0347 has the potential to be important in Lyme disease progression, and have begun to characterize the nature of the interaction between human fibronectin and this bacterial protein. Further work is needed to define the role of this protein in the borrelial infection process.

  14. In situ thermal evolution of B-B pairs in crystalline Si: a spectroscopic high resolution x-ray diffraction study

    Energy Technology Data Exchange (ETDEWEB)

    Bisognin, G; Salvador, D De; Napolitani, E; Carnera, A [MATIS CNR-INFM and Dipartimento di Fisica, Universita di Padova, via F Marzolo 8, 35131 Padova (Italy); Bruno, E; Mirabella, S; Piro, A M; Romano, L; Grimaldi, M G [MATIS CNR-INFM and Dipartimento di Fisica ed Astronomia, Universita di Catania, via S Sofia 64, 95123 Catania (Italy)], E-mail: bisognin@padova.infm.it

    2008-04-30

    The lattice strain induced by the thermal evolution of B-B pairs formed in a Si{sub 1-x}B{sub x}/Si layer as a consequence of He irradiation has been studied in situ in an N{sub 2} atmosphere, by using a high resolution x-ray diffractometer equipped with a hot stage sample holder. The collection of repeated rocking curves during a linear temperature (T) ramp allowed monitoring of the effects of the B-B pair thermal evolution on the epilayer lattice parameter a (and equally its strain) during the whole of the annealing from room T up to their complete dissolution (883 deg. C). By analysing the evolution of a(T) we extracted detailed information about the kinetics of B-B pair evolution. This allowed us to determine an experimental description of the B-B pair dissolution path in good agreement with recent ab initio calculations.

  15. Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88

    Science.gov (United States)

    2012-07-27

    Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88...Maryland, United States of America Abstract Staphylococcal enterotoxin B (SEB) exposure triggers an exaggerated pro-inflammatory cytokine response...Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88

  16. Cross-Feeding between Bifidobacterium longum BB536 and Acetate-Converting, Butyrate-Producing Colon Bacteria during Growth on Oligofructose▿

    OpenAIRE

    Falony, Gwen; Vlachou, Angeliki; Verbrugghe, Kristof; De Vuyst, Luc

    2006-01-01

    In vitro coculture fermentations of Bifidobacterium longum BB536 and two acetate-converting, butyrate-producing colon bacteria, Anaerostipes caccae DSM 14662 and Roseburia intestinalis DSM 14610, with oligofructose as the sole energy source, were performed to study interspecies interactions. Two clearly distinct types of cross-feeding were identified. A. caccae DSM 14662 was not able to degrade oligofructose but could grow on the fructose released by B. longum BB536 during oligofructose break...

  17. A randomised double-blind placebo-controlled trial with Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp. lactis BB-12 for maintenance of remission in ulcerative colitis

    DEFF Research Database (Denmark)

    Nordgaard, Inge; Rumessen, Jüri Johs.; Wildt, Signe

    2011-01-01

    To investigate the clinical effect of treatment with Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp. lactis BB-12 (Probio-Tec AB-25) to maintain remission in patients with ulcerative colitis.......To investigate the clinical effect of treatment with Lactobacillus acidophilus La-5 and Bifidobacterium animalis subsp. lactis BB-12 (Probio-Tec AB-25) to maintain remission in patients with ulcerative colitis....

  18. THREE-DIMENSIONAL FINITE-ELEMENT SIMULATION OF STRETCHING TECHNOLOGICAL PARAMETERS bt/h AND bb/h OF HEAVY FORGINGS

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A three-dimensional finite-element simulation of stretching technological parameters of heavy forgings is performed by using ANSYS program. The law of internal stress distribution with different bt/h (tool width ratio) and different bb/h (blank width ratio) is studied. Consequently, the critical tool width ratio( bt/h )cr and blank width ratio( bb/h )cr leading no bi-axial tension are obtained. It lays a credible foundation for designing reasonable stretching technology.

  19. Preclinical Toxicology Studies of Recombinant Human Platelet-Derived Growth Factor-BB Either Alone or in Combination with Beta-Tricalcium Phosphate and Type I Collagen

    Directory of Open Access Journals (Sweden)

    Conan S. Young

    2010-01-01

    Full Text Available Human platelet-derived growth factor-BB (hPDGF-BB is a basic polypeptide growth factor released from platelets at the injury site. It is a multifunctional molecule that regulates DNA synthesis and cell division and induces biological effects that are implicated in tissue repair, atherosclerosis, inflammatory responses, and neoplastic diseases. This paper is an overview of the toxicology data generated from a broad testing platform to determine bone, soft tissue, and systemic responses following administration of rhPDGF-BB. Moreover, the systemic and local toxicity of recombinant human PDGF-BB (rhPDGF-BB in combination with either beta-tricalcium phosphate (β-TCP or collagen combined with β-TCP was studied to determine dermal sensitization, irritation, intramuscular tissue responses, pyrogenicity, genotoxicity, and hemolytic properties. All data strongly suggest that rhPDGF-BB either alone or in combination with β-TCP or collagen with β-TCP is biocompatible and has neither systemic nor local toxicity, supporting its safe use in enhancing wound healing in patients.

  20. Cry3Bb1-Resistant Western Corn Rootworm, Diabrotica virgifera virgifera (LeConte) Does Not Exhibit Cross-Resistance to DvSnf7 dsRNA

    Science.gov (United States)

    Khajuria, Chitvan; Pleau, Michael; Ilagan, Oliver; Chen, Mao; Jiang, Changjian; Price, Paula; McNulty, Brian; Clark, Thomas; Head, Graham

    2017-01-01

    Background and Methodology There is a continuing need to express new insect control compounds in transgenic maize against western corn rootworm, Diabrotica virgifera virgifera (LeConte) (WCR). In this study three experiments were conducted to determine cross-resistance between the new insecticidal DvSnf7 dsRNA, and Bacillus thuringiensis (Bt) Cry3Bb1; used to control WCR since 2003, with field-evolved resistance being reported. Laboratory susceptible and Cry3Bb1-resistant WCR were evaluated against DvSnf7 dsRNA in larval diet-incorporation bioassays. Additionally, the susceptibility of seven field and one field-derived WCR populations to DvSnf7 (and Cry3Bb1) was assessed in larval diet-overlay bioassays. Finally, beetle emergence of laboratory susceptible and Cry3Bb1-resistant WCR was evaluated with maize plants in the greenhouse expressing Cry3Bb1, Cry34Ab1/Cry35Ab1, or DvSnf7 dsRNA singly, or in combination. Principal Findings and Conclusions The Cry3Bb1-resistant colony had slight but significantly (2.7-fold; PIRM tool against WCR that will increase the durability of these Bt proteins. These results also illustrate the importance of using appropriate bioassay methods when characterizing field-evolved resistant WCR populations. PMID:28060922

  1. MyNewsFlash: A System for Near Real-Time Variable Star Monitoring and Alerts

    Science.gov (United States)

    Price, A.; Turner, R.; Malatesta, K.; Simonsen, M. A.

    2004-12-01

    MyNewsFlash is an automated and customizable system for distributing timely variable star data. It supplies near real-time reports to the user of the latest activity of a variable star or class of stars. The stars it monitors, the frequency of report delivery, the delivery format, and more features are all completely customizable so the reader receives only reports of information he or she wants and nothing more or less. In addition, manually-generated alerts called Special MyNewsFlashes are occasionally sent out with additional information on special or abnormal behavior of a variable star. MyNewsFlash evolved from the AAVSO News Flash, an electronic publication dedicated to outbursts of popular cataclysmic variable stars

  2. Effects of PDGF-BB on migration and proliferation of SK-BR-3 mammary carcinoma cells%PDGF-BB 对 SK-BR-3乳腺癌细胞迁移、增殖的影响

    Institute of Scientific and Technical Information of China (English)

    步玉辉; 史建红; 崔乃鹏; 何欢; 王冰; 陈保平

    2014-01-01

    目的:观察血小板源性生长因子(PDGF)-BB对乳腺癌SK-BR-3细胞迁移、增殖的促进作用。方法分别以0.5、1、2、4ng/mL质量浓度的PDGF-BB干预对数期SK-BR-3乳腺癌细胞,细胞计数法和內盐法(MTS)检测细胞增殖情况,细胞迁移试验检测细胞迁移能力。结果与未加入任何药物的SK-BR-3乳腺癌细胞相比,4ng/mL的PDGF-BB对SK-BR-3乳腺癌细胞的迁移及增殖有明显促进作用,该促进作用与药物质量浓度呈正相关。结论在一定质量浓度范围内,PDGF-BB能明显促进人源性SK-BR-3细胞的迁移和增殖。%Objective To explore the effects of platelet-derived growth factor ( PDGF)-BB on the migration and prolif-eration of SK-BR-3 mammary carcinoma cells .Methods SK-BR-3 mammary carcinoma cells in logarithm growth stage were treated with different concentrations of PDGF-BB (0.5, 1, 2, 4 ng/mL).The proliferation was determined by cytom-etry and MTS assay , and the migration ability was detected by cell migration assay .Results Compared with SK-BR-3 mammary carcinoma cells without any drug , 4 ng/mL PDGF-BB promoted the migration and proliferation of SK-BR-3 mam-mary cells and it was positively associated with the drug concentration .Conclusions The PDGF-BB can promote the mi-gration and proliferation of human SK-BR-3 cells in a specific concentration range .

  3. BB-RTU在油田天然气监测系统中的应用%The Application of BB-RTU to the Monitor and Control System of Gas & Oil Field

    Institute of Scientific and Technical Information of China (English)

    陈永军; 魏灵芝; 翁惠辉; 张贤强

    2006-01-01

    文章研究的对象是基于Internet的SCADA数据传输系统.根据天然气网络体系结构不断扩大和天然气数据实时性不断提高的要求,结合青海油田天然气公司的微机管理系统,设计并实现了基于BB-RTU的SCADA数据传输系统.

  4. 益生菌BB-46及LA-5在酸奶中的应用%Application of probiotics the BB-46 and LA-5 in yogurt

    Institute of Scientific and Technical Information of China (English)

    胡姝敏; 杨秀茹; 谢永民

    2007-01-01

    首先介绍了我国益生菌酸奶的发展现状及趋势,然后通过试验研制出一种益生菌酸奶.从酸奶的发酵过程上严格控制,刚发酵结束产品总菌数高达109g-1,尤其益生菌LA-5及BB-46活菌数在保质期内均达到106g-1以上、且该产品获得很好的感官质量.

  5. Independent action between DvSnf7 RNA and Cry3Bb1 protein in southern corn rootworm, Diabrotica undecimpunctata howardi and Colorado potato beetle, Leptinotarsa decemlineata.

    Directory of Open Access Journals (Sweden)

    Steven L Levine

    Full Text Available In recent years, corn rootworm (CRW-resistant maize events producing two or more CRW-active Bt proteins have been commercialized to enhance efficacy against the target pest(s by providing multiple modes of action (MoA. The maize hybrid MON 87411 has been developed that produces the CRW-active Cry3Bb1 Bt protein (hereafter Cry3Bb1 and expresses a RNAi-mediated MoA that also targets CRW. As part of an environmental risk assessment for MON 87411, the potential for an interaction between the CRW-active DvSnf7 RNA (hereafter DvSnf7 and Cry3Bb1 was assessed in 12-day diet incorporation bioassays with the southern corn rootworm (SCR, Diabrotica undecimpunctata howardi. The potential for an interaction between DvSnf7 and Cry3Bb1 was evaluated with two established experimental approaches. The first approach evaluated each substance alone and in combination over three different response levels. For all three response levels, observed responses were shown to be additive and not significantly different from predicted responses under the assumption of independent action. The second approach evaluated the potential for a fixed sub-lethal concentration of Cry3Bb1 to decrease the median lethal concentration (LC50 of DvSnf7 and vice-versa. With this approach, the LC50 value of DvSnf7 was not altered by a sub-lethal concentration of Cry3Bb1 and vice-versa. In addition, the potential for an interaction between the Cry3Bb1 and DvSnf7 was tested with Colorado potato beetle (CPB, Leptinotarsa decemlineata, which is sensitive to Cry3Bb1 but not DvSnf7. CPB assays also demonstrated that DvSnf7 does not alter the activity of Cry3Bb1. The results from this study provide multiple lines of evidence that DvSnf7 and Cry3Bb1 produced in MON 87411 have independent action.

  6. Effect of recombinant human platelet-derived growth factor-BB-coated sutures on Achilles tendon healing in a rat model: A histological and biomechanical study

    Directory of Open Access Journals (Sweden)

    Stephen H Cummings

    2012-12-01

    Full Text Available Purpose: Repairing tendon injuries with recombinant human platelet-derived growth factor-BB has potential for improving surgical outcomes. Augmentation of sutures, a critical component of surgical tendon repair, by coating with growth factors may provide a clinically useful therapeutic device for improving tendon repair. Therefore, the purpose of this study was to (a coat Vicryl sutures with a defined dose of recombinant human platelet-derived growth factor-BB without additional coating excipients (e.g. gelatin, (b quantify the recombinant human platelet-derived growth factor-BB released from the suture, and (c use the recombinant human platelet-derived growth factor-BB-coated sutures to enhance tendon repair in a rat Achilles tendon transection model. Methods: Vicryl sutures were coated with 0, 0.3, 1.0, and 10.0 mg/mL concentrations of recombinant human platelet-derived growth factor-BB using a dip-coating process. In vitro release was quantified by an enzyme-linked immunosorbent assay. Acutely transected rat Achilles tendons were repaired using one of the four suture groups (n = 12 per group. Four weeks following repair, the tensile biomechanical and histological (i.e. collagen organization and angiogenesis properties were determined. Results: A dose-dependent bolus release of recombinant human platelet-derived growth factor-BB occurred within the first hour in vitro, followed by a gradual release over 48 h. There was a significant increase in ultimate tensile strength (p < 0.01 in the two highest recombinant human platelet-derived growth factor-BB dose groups (1.9 ± 0.5 and 2.1 ± 0.5 MPa relative to controls (1.0 ± 0.2 MPa. The modulus significantly increased (p = 0.031 with the highest recombinant human platelet-derived growth factor-BB dose group (7.2 ± 3.8 MPa relative to all other groups (control: 3.5 ± 0.9 MPa. No significant differences were identified for the maximum load or stiffness. The histological collagen and angiogenesis

  7. The Vestal Cataclysm

    Science.gov (United States)

    Cohen, Barbara A.

    2012-01-01

    The currently operating Dawn mission shows asteroid 4 Vesta to be an extensively cratered body, with craters in a variety of morphologies and preservation states The crater size-frequency distribution for Vesta, modeled using the lunar chronology and scaled to impact frequencies modeled for Vesta, shows that both the north and south pole areas are ancient in age [1]. We have in our meteorite collection products from 4 Vesta in the form of the HED (howardite, eucrite, diogenite) meteorites. The HED parent body globally differentiated and fully crystallized by approx.4.56 Ga; subsequently, the eucrites were brecciated and heated by large impacts into the parent body surface, reflected in their disturbance ages [2, 3]. Dawn images have also shown that Vesta is covered with a well-developed regolith that is spectrally similar to howardite meteorites [4, 5]. Howardites are polymict regolith breccias made up mostly of clasts of eucrites and diogenites, but which also contain clasts formed by impact into the regolith. Impact-melt clast ages from howardites extend our knowledge of the impact history of Vesta, expanding on eucrite disturbance ages and helping give absolute age context to the observed crater-counts on Vesta.

  8. Computing Cosmic Cataclysms

    Science.gov (United States)

    Centrella, Joan M.

    2010-01-01

    The final merger of two black holes releases a tremendous amount of energy, more than the combined light from all the stars in the visible universe. This energy is emitted in the form of gravitational waves, and observing these sources with gravitational wave detectors requires that we know the pattern or fingerprint of the radiation emitted. Since black hole mergers take place in regions of extreme gravitational fields, we need to solve Einstein's equations of general relativity on a computer in order to calculate these wave patterns. For more than 30 years, scientists have tried to compute these wave patterns. However, their computer codes have been plagued by problems that caused them to crash. This situation has changed dramatically in the past few years, with a series of amazing breakthroughs. This talk will take you on this quest for these gravitational wave patterns, showing how a spacetime is constructed on a computer to build a simulation laboratory for binary black hole mergers. We will focus on the recent advances that are revealing these waveforms, and the dramatic new potential for discoveries that arises when these sources will be observed.

  9. Very-high-energy -ray observations of pulsar wind nebulae and cataclysmic variable stars with MAGIC and development of trigger systems for IACTs

    OpenAIRE

    López Coto, Rubén

    2015-01-01

    La historia de la astronomía es tan antigua como alcanzan nuestros registros. Todas las civilizaciones han estado interesadas en el estudio del cielo nocturno, sus objetos y fenómenos. Estas observaciones se realizaron a simple vista hasta el comienzo del siglo XVII, cuando Galileo Galilei empezó a usar un instrumento desarrollado recientemente llamado telescopio. Desde entonces, el rango de longitudes de onda accesible ha ido creciendo, con una explosión en el siglo XX gracias...

  10. Very-high-energy -ray observations of pulsar wind nebulae and cataclysmic variable stars with MAGIC and development of trigger systems for IACTs

    OpenAIRE

    López Coto, Rubén; Fernández Sánchez, Enrique

    2015-01-01

    La historia de la astronomía es tan antigua como alcanzan nuestros registros. Todas las civilizaciones han estado interesadas en el estudio del cielo nocturno, sus objetos y fenómenos. Estas observaciones se realizaron a simple vista hasta el comienzo del siglo XVII, cuando Galileo Galilei empezó a usar un instrumento desarrollado recientemente llamado telescopio. Desde entonces, el rango de longitudes de onda accesible ha ido creciendo, con una explosión en el siglo XX gracias al desarrollo ...

  11. ASCA Observations of the Dwarf Novae SS Cyg and VW Hyi And Observations of the Precessing Disk Cataclysmic Variable TV Col

    Science.gov (United States)

    Schlegel, E.; Swank, Jean (Technical Monitor)

    2001-01-01

    The observations for both SS Cyg and VW Hyi were to be scheduled as Targets of Opportunity jointly with other satellites. The VW Hyi observation was obtained jointly with EUVE during a superoutburst. The XTE data were initially processed, revealing no detection. However, the XTE team improved the instrumental background model and distributed it in July 1998. A further improvement was made in August 1999. The improved models allow a better background subtraction, thereby detecting previously un-detected sources.

  12. Blocking the 4-1BB Pathway Ameliorates Crystalline Silica-induced Lung Inflammation and Fibrosis in Mice.

    Science.gov (United States)

    Li, Chao; Du, Sitong; Lu, Yiping; Lu, Xiaowei; Liu, Fangwei; Chen, Ying; Weng, Dong; Chen, Jie

    2016-01-01

    Long term pulmonary exposure to crystalline silica leads to silicosis that manifests progressive interstitial fibrosis, eventually leading to respiratory failure and death. Despite efforts to eliminate silicosis, clinical cases continue to occur in both developing and developed countries. The exact mechanisms of crystalline silica-induced pulmonary fibrosis remain elusive. Herein, we find that 4-1BB is induced in response to crystalline silica injury in lungs and that it is highly expressed during development of experimental silicosis. Therefore, we explore the role of 4-1BB pathway during crystalline silica-induced lung injury and find that a specific inhibitor blocking the pathway could effectively alleviate crystalline silica-induced lung inflammation and subsequent pulmonary fibrosis in vivo. Compared to controls, the treated mice exhibited reduced Th1 and Th17 responses. The concentrations of pro-inflammatory cytokines in bronchoalveolar lavage fluid (BALF), including tumor necrosis factor (TNF)-α, interferon (IFN)-γ and interleukin (IL)-17A following crystalline silica challenge were also reduced in inhibitor-treated mice. Although there was no significant alteration in Th2 cytokines of IL-4 and IL-13, another type of pro-fibrogenic cell, regulatory T cell (Treg) was significantly affected. In addition, one of the major participants in fibrogenesis, fibrocyte recruited less due to the blockade. Furthermore, we demonstrated the decreased fibrocyte recruitment was associated with chemokine reductions in lung. Our study discovers the 4-1BB pathway signaling enhances inflammatory response and promotes pulmonary fibrosis induced by crystalline silica. The findings here provide novel insights into the molecular events that control crystalline silica-induced lung inflammation and fibrosis through regulating Th responses and the recruitment of fibrocytes in crystalline silica-exposed lung.

  13. Leukemia-specific T-cell reactivity induced by leukemic dendritic cells is augmented by 4-1BB targeting.

    Science.gov (United States)

    Houtenbos, Ilse; Westers, Theresia M; Dijkhuis, Annemiek; de Gruijl, Tanja D; Ossenkoppele, Gert J; van de Loosdrecht, Arjan A

    2007-01-01

    Acute myelogenous leukemia (AML) blasts are able to differentiate into leukemia-derived dendritic cells (AML-DC), thereby enabling efficient presentation of known and unknown leukemic antigens. Advances in culture techniques and AML-DC characterization justify clinical application. However, additional measures are likely needed to potentiate vaccines and overcome the intrinsic tolerant state of the patients' immune system. Engagement of the costimulatory molecule 4-1BB can break immunologic tolerance and increase CTL responses. In this study, we examined the role of the 4-1BB ligand (4-1BBL) on T-cell responses induced by AML-DC. In allogeneic and autologous cocultures of T cells and AML-DC, the effect of the addition of 4-1BBL on T-cell proliferation, T-cell subpopulations, and T-cell function was determined. Addition of 4-1BBL to cocultures of AML-DC and T cells induced a preferential increase in the proliferation of CD8(+) T cells. Increased differentiation into effector and central memory populations was observed in both CD4(+) and CD8(+) T cells in the presence of 4-1BBL. AML-DC induce a T helper 1 response, characterized by high IFN-gamma production, which is significantly increased by targeting 4-1BB. T cells primed in the presence of 4-1BBL show specificity for the leukemia-associated antigen Wilms' tumor 1, whereas cytotoxicity assays with leukemic blast targets showed the cytolytic potential of T cells primed in the presence of 4-1BBL. We conclude that 4-1BBL is an effective adjuvant to enhance T-cell responses elicited by AML-DC.

  14. Piperine inhibits platelet-derived growth factor-BB-induced proliferation and migration in vascular smooth muscle cells.

    Science.gov (United States)

    Lee, Kang Pa; Lee, Kwan; Park, Won-Hwan; Kim, Hyuck; Hong, Heeok

    2015-02-01

    The proliferation and migration of vascular smooth muscle cells (VSMCs) in blood vessels are important in the pathogenesis of vascular disorders such as atherosclerosis and restenosis. Piperine, a major component of black pepper, has antioxidant, anticancer, and anti-inflammatory activity. However, the antiatherosclerotic effects of piperine have not been investigated. In this study, the effects of piperine on platelet-derived growth factor (PDGF)-BB-induced proliferation and migration of VSMCs were investigated. The antiproliferative effects of piperine were determined using MTT assays, cell counting, real-time polymerase chain reaction, and western blots. Our results showed that piperine significantly attenuated the proliferation of VSMCs by increasing the expression of p27(kip1), regulating the mRNA expression of cell cycle enzymes (cyclin D, cyclin E, and PCNA), and decreasing the phosphorylation of extracellular signal-regulated kinase (ERK)1/2 in a noncytotoxic concentration-dependent manner (30-100 μM). Moreover, we examined the effects of piperine on the migration of PDGF-BB-stimulated VSMCs, as determined by the Boyden chamber assay, H2DCFDA staining, and western blots. Our results showed that 100 μM piperine decreased cell migration, the production of reactive oxygen species (ROS), and phosphorylation of the p38 mitogen-activated protein kinase (MAPK). Taken together, our results suggest that piperine inhibits PDGF-BB-induced proliferation and the migration of VSMCs by inducing cell cycle arrest and suppressing MAPK phosphorylation and ROS. These findings suggest that piperine may be beneficial for the treatment of vascular-related disorders and diseases.

  15. Association between Virulence Factors and TRAF1/4-1BB/Bcl-xL Expression in Gastric Mucosa Infected with Helicobacter pylori

    Directory of Open Access Journals (Sweden)

    Fen Wang

    2015-01-01

    Full Text Available Objective. CagA+/vacAs1+/vacAm1+ Helicobacter pylori upregulates the expression of tumor necrosis factor receptor–associated factor 1 (TRAF1, tumor necrosis factor receptor superfamily member 9 (4-1BB, and B-cell lymphoma-extra large (Bcl-xL in human gastric epithelial cells. We investigated the correlation between cagA/vacAs1/vacAm1 and TRAF1/4-1BB/Bcl-xL expression in gastric mucosal tissue of patients with gastric disorders. Methods. We collected gastric mucosa samples from 35 chronic, nonatrophic gastritis (CG patients, 41 atrophic gastritis patients, 44 intestinal metaplasia with atypical hyperplasia (IM patients, and 28 gastric carcinoma (Ca patients. The expression of  TRAF1, 4-1BB, and Bcl-xL was determined using western blotting. The expression of cagA, vacAs1, and vacAm1 in H. pylori was examined with polymerase chain reaction. Results. The expression of TRAF1, 4-1BB, and Bcl-xL was significantly upregulated in IM and Ca patients (P<0.05 compared with CG. There were more cases of cagA+/vacAs1+/vacAm1+ H. pylori infection in samples with elevated TRAF1, 4-1BB, or Bcl-xL expression (P<0.05. Additionally, there were a remarkably large number of samples with upregulated TRAF1/4-1BB/Bcl-xL expression in cases of cagA+/vacAs1+/vacAm1+ H. pylori infection (44 cases, 67.7%; P<0.05. Conclusions. The pathogenesis of IM and Ca may be promoted by cagA+/vacAs1+/vacAm1+ H. pylori, possibly via upregulated TRAF1, 4-1BB, and Bcl-xL in gastric mucosal tissue.

  16. Iodine and tri-iodo-thyronine reduce the incidence of type 1 diabetes mellitus in the autoimmune prone BB rats

    DEFF Research Database (Denmark)

    Hartoft-Nielsen, Marie-Louise; Rasmussen, Aase Krogh; Bock, Troels;

    2009-01-01

    Thyroid hormones modulate the immune system and metabolism, influence insulin secretion, and cause decreased glucose tolerance. Thyroid hormones have been described to change the incidence of spontaneous autoimmune thyroiditis in Bio-Breeding/Worcester (BB) rats but it is unknown how these hormones...... iodine (NaI) or thyroid stimulating hormone (TSH) neonatally or with tri-iodo-thyronine (T3) during adolescence. At the age of 19 weeks the incidence of T1DM and the degree of insulitis were evaluated. The influence of T3 treatment on the beta cell mass was evaluated in Wistar rats by unbiased...

  17. Differentiation of Murine Bone Marrow-Derived Smooth Muscle Progenitor Cells Is Regulated by PDGF-BB and Collagen.

    Directory of Open Access Journals (Sweden)

    Clifford Lin

    Full Text Available Smooth muscle cells (SMCs are key regulators of vascular disease and circulating smooth muscle progenitor cells may play important roles in vascular repair or remodelling. We developed enhanced protocols to derive smooth muscle progenitors from murine bone marrow and tested whether factors that are increased in atherosclerotic plaques, namely platelet-derived growth factor-BB (PDGF-BB and monomeric collagen, can influence the smooth muscle specific differentiation, proliferation, and survival of mouse bone marrow-derived progenitor cells. During a 21 day period of culture, bone marrow cells underwent a marked increase in expression of the SMC markers α-SMA (1.93 ± 0.15 vs. 0.0008 ± 0.0003 (ng/ng GAPDH at 0 d, SM22-α (1.50 ± 0.27 vs. 0.005 ± 0.001 (ng/ng GAPDH at 0 d and SM-MHC (0.017 ± 0.004 vs. 0.001 ± 0.001 (ng/ng GAPDH at 0 d. Bromodeoxyuridine (BrdU incorporation experiments showed that in early culture, the smooth muscle progenitor subpopulation could be identified by high proliferative rates prior to the expression of smooth muscle specific markers. Culture of fresh bone marrow or smooth muscle progenitor cells with PDGF-BB suppressed the expression of α-SMA and SM22-α, in a rapidly reversible manner requiring PDGF receptor kinase activity. Progenitors cultured on polymerized collagen gels demonstrated expression of SMC markers, rates of proliferation and apoptosis similar to that of cells on tissue culture plastic; in contrast, cells grown on monomeric collagen gels displayed lower SMC marker expression, lower growth rates (319 ± 36 vs. 635 ± 97 cells/mm2, and increased apoptosis (5.3 ± 1.6% vs. 1.0 ± 0.5% (Annexin 5 staining. Our data shows that the differentiation and survival of smooth muscle progenitors are critically affected by PDGF-BB and as well as the substrate collagen structure.

  18. THE TIME DOMAIN SPECTROSCOPIC SURVEY: VARIABLE SELECTION AND ANTICIPATED RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Morganson, Eric; Green, Paul J. [Harvard Smithsonian Center for Astrophysics, 60 Garden St, Cambridge, MA 02138 (United States); Anderson, Scott F.; Ruan, John J. [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Myers, Adam D. [Department of Physics and Astronomy, University of Wyoming, Laramie, WY 82071 (United States); Eracleous, Michael; Brandt, William Nielsen [Department of Astronomy and Astrophysics, 525 Davey Laboratory, The Pennsylvania State University, University Park, PA 16802 (United States); Kelly, Brandon [Department of Physics, Broida Hall, University of California, Santa Barbara, CA 93106-9530 (United States); Badenes, Carlos [Department of Physics and Astronomy and Pittsburgh Particle Physics, Astrophysics and Cosmology Center (PITT PACC), University of Pittsburgh, 3941 O’Hara St, Pittsburgh, PA 15260 (United States); Bañados, Eduardo [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117 Heidelberg (Germany); Blanton, Michael R. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); Bershady, Matthew A. [Department of Astronomy, University of Wisconsin, 475 N. Charter St., Madison, WI 53706 (United States); Borissova, Jura [Instituto de Física y Astronomía, Universidad de Valparaíso, Av. Gran Bretaña 1111, Playa Ancha, Casilla 5030, and Millennium Institute of Astrophysics (MAS), Santiago (Chile); Burgett, William S. [GMTO Corp, Suite 300, 251 S. Lake Ave, Pasadena, CA 91101 (United States); Chambers, Kenneth, E-mail: emorganson@cfa.harvard.edu [Institute for Astronomy, University of Hawaii at Manoa, Honolulu, HI 96822 (United States); and others

    2015-06-20

    We present the selection algorithm and anticipated results for the Time Domain Spectroscopic Survey (TDSS). TDSS is an Sloan Digital Sky Survey (SDSS)-IV Extended Baryon Oscillation Spectroscopic Survey (eBOSS) subproject that will provide initial identification spectra of approximately 220,000 luminosity-variable objects (variable stars and active galactic nuclei across 7500 deg{sup 2} selected from a combination of SDSS and multi-epoch Pan-STARRS1 photometry. TDSS will be the largest spectroscopic survey to explicitly target variable objects, avoiding pre-selection on the basis of colors or detailed modeling of specific variability characteristics. Kernel Density Estimate analysis of our target population performed on SDSS Stripe 82 data suggests our target sample will be 95% pure (meaning 95% of objects we select have genuine luminosity variability of a few magnitudes or more). Our final spectroscopic sample will contain roughly 135,000 quasars and 85,000 stellar variables, approximately 4000 of which will be RR Lyrae stars which may be used as outer Milky Way probes. The variability-selected quasar population has a smoother redshift distribution than a color-selected sample, and variability measurements similar to those we develop here may be used to make more uniform quasar samples in large surveys. The stellar variable targets are distributed fairly uniformly across color space, indicating that TDSS will obtain spectra for a wide variety of stellar variables including pulsating variables, stars with significant chromospheric activity, cataclysmic variables, and eclipsing binaries. TDSS will serve as a pathfinder mission to identify and characterize the multitude of variable objects that will be detected photometrically in even larger variability surveys such as Large Synoptic Survey Telescope.

  19. The Time Domain Spectroscopic Survey: Variable Selection and Anticipated Results

    Science.gov (United States)

    Morganson, Eric; Green, Paul J.; Anderson, Scott F.; Ruan, John J.; Myers, Adam D.; Eracleous, Michael; Kelly, Brandon; Badenes, Carlos; Bañados, Eduardo; Blanton, Michael R.; Bershady, Matthew A.; Borissova, Jura; Brandt, William Nielsen; Burgett, William S.; Chambers, Kenneth; Draper, Peter W.; Davenport, James R. A.; Flewelling, Heather; Garnavich, Peter; Hawley, Suzanne L.; Hodapp, Klaus W.; Isler, Jedidah C.; Kaiser, Nick; Kinemuchi, Karen; Kudritzki, Rolf P.; Metcalfe, Nigel; Morgan, Jeffrey S.; Pâris, Isabelle; Parvizi, Mahmoud; Poleski, Radosław; Price, Paul A.; Salvato, Mara; Shanks, Tom; Schlafly, Eddie F.; Schneider, Donald P.; Shen, Yue; Stassun, Keivan; Tonry, John T.; Walter, Fabian; Waters, Chris Z.

    2015-06-01

    We present the selection algorithm and anticipated results for the Time Domain Spectroscopic Survey (TDSS). TDSS is an Sloan Digital Sky Survey (SDSS)-IV Extended Baryon Oscillation Spectroscopic Survey (eBOSS) subproject that will provide initial identification spectra of approximately 220,000 luminosity-variable objects (variable stars and active galactic nuclei across 7500 deg2 selected from a combination of SDSS and multi-epoch Pan-STARRS1 photometry. TDSS will be the largest spectroscopic survey to explicitly target variable objects, avoiding pre-selection on the basis of colors or detailed modeling of specific variability characteristics. Kernel Density Estimate analysis of our target population performed on SDSS Stripe 82 data suggests our target sample will be 95% pure (meaning 95% of objects we select have genuine luminosity variability of a few magnitudes or more). Our final spectroscopic sample will contain roughly 135,000 quasars and 85,000 stellar variables, approximately 4000 of which will be RR Lyrae stars which may be used as outer Milky Way probes. The variability-selected quasar population has a smoother redshift distribution than a color-selected sample, and variability measurements similar to those we develop here may be used to make more uniform quasar samples in large surveys. The stellar variable targets are distributed fairly uniformly across color space, indicating that TDSS will obtain spectra for a wide variety of stellar variables including pulsating variables, stars with significant chromospheric activity, cataclysmic variables, and eclipsing binaries. TDSS will serve as a pathfinder mission to identify and characterize the multitude of variable objects that will be detected photometrically in even larger variability surveys such as Large Synoptic Survey Telescope.

  20. Spectral eclipse mapping of the accretion disk in the nova-like variable UX Ursae Majoris

    Science.gov (United States)

    Rutten, R. G. M.; Dhillon, V. S.; Horne, K.; Kuulkers, E.

    1994-01-01

    We analyze narrow-band eclipse light curves of the nova-like cataclysmic variable UX UMa, obtained from low-resolution spectra spanning lambda lambda 3600-9800 A . The light curves for narrow bands in the continuum as well as those for individual spectral lines are treated independently, and are used to construct images of the accretion disk's brightness distribution using the maximum-entropy eclipse-mapping technique. Particular attention is paid to the propagation of statistical uncertainties in the data and to how the analysis may introduce systematic errors in the final result. From the many narrrow band images we have reconstructed the spectra from isolated parts of the accretion disk. These spectra reveal that the inner disk radiates a continuum spectrum which peaks in the near UV and has the hydrogen Balmer lines in absorption (with the exception of H-alpha), whereas the outer disk is much fainter, has a much redder spectrum, and has Balmer emission lines. Our analysis reveals the presence of an uneclipsed component of the total light, whose spectrum is very red and has Balmer lines in emission. This unexpected feature of the eclipse mapping technique offers a new tool for an independent assessment of the secondary star's spectrum in eclipsing cataclysmic variables.