WorldWideScience

Sample records for case study results

  1. Results of ozone measurements in Northern Germany: A case study

    Science.gov (United States)

    Schmidt, Manfred

    1994-01-01

    At most of the German ozone recording stations which have records over a sufficiently long period, the results of the summer months of 1989 showed the highest values since the beginning of the measurements. One of the reasons for this phenomenon was the high duration of sunshine in that summer; for example, in Potsdam near Berlin in May 1989 the sunshine duration was the highest in May since the beginning of the records in 1893. For that reason we selected this summer for a case study. The basis for the study was mainly the ozone measuring stations of the network of Lower Saxony and the Federal Office of Environment (Umweltbundesamt). The results of these summer measurements point to intense sources of ozone, probably in form of gaseous precursors, in the Middle German industrial areas near Leipzig and Halle and in Northwestern Czechoslovakia, with coal-mining, chemical and petrochemical industries, coking plants and others. The maps of average ozone concentrations, number or days with high ozone maxima, ozone-windroses of the stations, etc., suggest that these areas could be a main source of precursors and of photochemical ozone production in summer smog episodes in Central Europe. Stations on the North Sea coast, at which early ozone measurements were made by our institute in 1973/74 are compared with similarly located stations of the Lower Saxon network in 1989 and the results show a reversal of the ozone-windroses. In 1973/74, the highest ozone concentrations were correlated with wind directions from the sea while in 1989 these concentrations were correlated with directions from the continent. In the recent years, photochemical ozone production on the continent is probably predominant, while in former years the higher ozone content of the maritime subpolar air masses has been explained by stratospheric-tropospheric exchange.

  2. Case study on the results of image interpretation

    International Nuclear Information System (INIS)

    Hepatocellular carcinoma (HCC) most commonly produces a focal mass lesion which is initially hypoechoic, but becomes more echogenic with increasing size. Texture pattern characteristically produces mosaic appearance and is often accompanied by posterior echo enhancement. In some cases, the tumor infiltrates widely through the liver substance, giving rise to an irregular pattern, invasion of veins, hepatic and portal, is common. The incidence of intra and extrahepatic dissemination is high in HCC with diffuse infiltration. Liver scintigraphy, sonographic findings, clinical history and laboratory investigation were analysed and interpreted

  3. Evidence and knowledge use in a meta-policy: results from an Italian case study

    OpenAIRE

    Valente, Adriana; Castellani, Tommaso; Cori, Liliana; Bianchi, Fabrizio

    2013-01-01

    The analysis of the case study was conducted by means of qualitative content analysis of documents and interviews of 14 stakeholders involved in the policy making processes. In-depth interviews to five policy makers were carried out, and the emerging elements were compared with the results of the content analysis of the policy documents.

  4. Business Value Is not only Dollars - Results from Case Study Research on Agile Software Projects

    NARCIS (Netherlands)

    Racheva, Zornitza; Daneva, Maya; Sikkel, Klaas; Buglione, Luigi; Ali Babar, M.; Vierimaa, Matias; Oivo, Markku

    2010-01-01

    Business value is a key concept in agile software development. This paper presents results of a case study on how business value and its creation is perceived in the context of agile projects. Our overall conclusion is that the project participants almost never use an explicit and structured approac

  5. Psychoneuroimmunology: an interpretation of experimental and case study evidence towards a paradigm for predictable results.

    Science.gov (United States)

    Kalt, H W

    2000-07-01

    This paper surveys a number of key experiments and case studies relating to psychoneuroimmunology. It finds that most techniques to influence or even direct the immune system via the mind fall into a series of theoretical categories called passive, active and targeted effects. By examining the results of experiments and studies in the light of these categories a number of important conclusions are drawn. These conclusions explain differences in experimental results, describe those variables that appear to be central to obtaining results, and describe in detail where experimentation should be concentrated to further knowledge of psychoneuroimmunology.

  6. Organizational evaluation of an interprofessional study unit - Results from a Danish case study

    DEFF Research Database (Denmark)

    Jensen, Didde Cramer; Nørgaard, Birgitte; Draborg, Eva;

    2012-01-01

    This article presents results from an organizational evaluation of an interprofessional clinical study unit (ICS) in Denmark. The aim of this study was to test whether the ICS was based on a durable organizational concept and to identify the prerequisites for the unit to be successful. The...... for the study unit to function organizationally. Further analysis examined whether these conditions had been present during the project period and whether all elements had been correctly implemented. The results suggested that although the ICS had taken into account stakeholders' requests, it was not...

  7. Handling uncertainty in relation extraction: a case study on tennis tournament results extraction from tweets

    OpenAIRE

    Verburg, Jochem; Habib, Mena; Keulen, van, S.

    2015-01-01

    Relation extraction involves different types of uncertainty due to the imperfection of the extraction tools and the inherent ambiguity of unstructured text. In this paper, we discuss several ways of handling uncertainties in relation extraction from social media. Our study case is to extract tennis games’ results for two Grand Slam tennis tournaments from tweets. Analysis has been done to find to what extent it is useful to use semantic web, domain knowledge, facts repetition, and authors’ tr...

  8. Malnutrition and Childhood Disability in Turkana, Kenya: Results from a Case-Control Study.

    OpenAIRE

    Hannah Kuper; Velma Nyapera; Jennifer Evans; David Munyendo; Maria Zuurmond; Severine Frison; Victoria Mwenda; David Otieno; James Kisia

    2015-01-01

    Background Children with disabilities may be particularly vulnerable to malnutrition, as a result of exclusions and feeding difficulties. However, there is limited evidence currently available on this subject. Methods A population-based case-control study was conducted in Turkana County, Kenya, between July and August 2013. Key informants in the community identified children aged 6 months to 10 years who they believed may have a disability. These children were screened by a questionnaire (UNI...

  9. Organizational Crises and Reactions from a Legitimacy Perspective - Results from Two Multiple-case Studies

    OpenAIRE

    Breitsohl, Heiko

    2009-01-01

    Organizational crises can be conceptualized as interactions between organizations and stake-holders around the breach and reestablishment of common norms and social codes, i.e. per-ceptions of legitimacy. This paper contributes to the understanding of organizational crises by exploring the roles of dimensions of legitimacy in organizational crises as well as the role of different reactions in the resolution of crises. Results of two qualitative multiple-case studies based on analyses of media...

  10. Forest fuel procurement in Eastern Europe - case study results from Poland and Czech Republic

    Energy Technology Data Exchange (ETDEWEB)

    Virkkunen, M.; Leinonen, A. (VTT Technical Research Centre of Finland, Jyvaeskylae (Finland))

    2007-07-01

    This paper is an introduction to Bialys tok and Zabreh case studies that are a part of the ongoing Finnish research project 'Forest energy resources, energy technology market and biofuel trade in the EU' which is funded by the ClimBus programme of Tekes. The case studies consist of following three main tasks: 1. Forest biomass potential assessment 2. Forest fuel procurement cost study and 3. study on the economics of biomass based energy production. Biomass potential assessments (task 1) are carried out by METLA (Finnish Forest research Institute). The economical analyses and cost assessments (task 2 and 3) were carried out by VTT. Local bioenergy and forestry experts such as EC BREC in Poland and UHUL (Forest management Institute) in Czech Republic operated as a crucial link between Finnish research organizations, local authorities and companies in practical arrangements and in supplying necessary data for calculations Finnish companies Vapo Oy, Metso Power Oy, Waersilae Biopower Oy, Kesla Oy and Pentin Paja Oy delivered valuable business views and perspectives to the project. This paper introduces the main results from the tasks 1 and 2 of the Bialystok and Zabreh studies. The results provide information to the local energy producer of forest fuels as energy source. For Finnish bioenergy technology machine and appliance manufacturers the results act as part of market potential assessment tool in the study area. (orig.)

  11. Productivity of Pair Programming in a Distributed Environment - Results from Two Controlled Case Studies

    Science.gov (United States)

    Pietinen, Sami; Tenhunen, Vesa; Tukiainen, Markku

    Several methods and techniques have surfaced to address the ongoing concerns of quality and productivity of software development. Among these is the Pair Programming (PP) method, which has gained a lot off attention through being an essential part of an agile software development methodology called the eXtreme Programming (XP). In this paper, we present the results of two controlled case studies that investigate the possible productivity improvement through the incorporation of PP over solo programming. The main focus is on implementation task, more specifically in programming, although PP is suitable for other tasks too. Our results show that very high level of PP use might be difficult to achieve in a very tightly scheduled software development project, but some of the benefits can be seen to come true even with proportional use of PP. In our case, PP added the additional effort of 13% over solo programming.

  12. Bladder cancer among workers in the textile industry: results of a Spanish case-control study.

    Science.gov (United States)

    Gonzales, C A; Riboli, E; Lopez-Abente, G

    1988-01-01

    This paper presents results from a case-control study carried out in the county of Mataro, Spain. The study was designed to investigate the possible causes of an unusually high mortality rate from bladder cancer in Mataro county as compared to Spain as a whole, and this report focuses on occupational exposures. The study is based on 57 cases who were hospitalized for or died from bladder cancer between 1978 and 1981. Two controls per case were matched for sex, age, residence, and date of either hospitalization or death. Information was collected on smoking, coffee drinking, and occupation. Occupational histories were then evaluated and coded blind by a group of occupational health physicians. Analyses were carried out by means of conditional logistic regression. Among a group of common occupational sectors, an increased risk for past employment in the textile industry (OR = 2.2; p = .038) was found. Further analyses indicated that the risk is particularly elevated (OR = 4.41; 95% confidence limits; 1.15-16.84) for subjects who worked in dyeing or printing and who were most probably exposed to azo-dyes. Exposure in the textile industry may be responsible for 16% of the bladder cancers in the Mataro area. A list of dyes commonly used in the Mataro textile industries was compiled and cross-checked with lists of substances tested or evaluated for carcinogenesis.

  13. Bladder cancer among workers in the textile industry: results of a Spanish case-control study.

    Science.gov (United States)

    Gonzales, C A; Riboli, E; Lopez-Abente, G

    1988-01-01

    This paper presents results from a case-control study carried out in the county of Mataro, Spain. The study was designed to investigate the possible causes of an unusually high mortality rate from bladder cancer in Mataro county as compared to Spain as a whole, and this report focuses on occupational exposures. The study is based on 57 cases who were hospitalized for or died from bladder cancer between 1978 and 1981. Two controls per case were matched for sex, age, residence, and date of either hospitalization or death. Information was collected on smoking, coffee drinking, and occupation. Occupational histories were then evaluated and coded blind by a group of occupational health physicians. Analyses were carried out by means of conditional logistic regression. Among a group of common occupational sectors, an increased risk for past employment in the textile industry (OR = 2.2; p = .038) was found. Further analyses indicated that the risk is particularly elevated (OR = 4.41; 95% confidence limits; 1.15-16.84) for subjects who worked in dyeing or printing and who were most probably exposed to azo-dyes. Exposure in the textile industry may be responsible for 16% of the bladder cancers in the Mataro area. A list of dyes commonly used in the Mataro textile industries was compiled and cross-checked with lists of substances tested or evaluated for carcinogenesis. PMID:3232687

  14. Associations of depression and depressive symptoms with preeclampsia: results from a Peruvian case-control study

    Directory of Open Access Journals (Sweden)

    Garcia Pedro

    2007-09-01

    Full Text Available Abstract Background Preeclampsia involves endothelial dysfunction, platelet dysfunction/activation and sympathetic over-activity similar to cardiovascular disorders (CVD. Depression, an independent risk factor for progression of CVD, was found to be associated with an increased risk of preeclampsia among Finnish women. We examined the relation between depression/depressive symptoms and preeclampsia risk among Peruvian women. Methods The study included 339 preeclamptic cases and 337 normotensive controls. Depression and depressive symptoms during pregnancy were assessed using the Patient Health Questionnaire (PHQ-9. Odds ratios (OR and 95% confidence intervals (CI were estimated from logistic regression models. Results The prevalence of moderate depression was 11.5% among cases and 5.3% among controls. The corresponding figures for moderate-severe depression were 3.5% for cases and 2.1% for controls. Compared with non-depressed women, those with moderate depression had a 2.3-fold increased risk of preeclampsia (95% CI: 1.2–4.4, while moderate-severe depression was associated with a 3.2-fold (95% CI: 1.1–9.6 increased risk of preeclampsia. Associations of each of the 9-items of the PHQ-9 depression screening module with preeclampsia risk were also observed. Conclusion Our findings are consistent with the only other published report on this topic. Collectively, available data support recent calls for expanded efforts to study and address depression among pregnant women.

  15. Primary cesarean delivery results in emergency hysterectomy due to placenta accreta: a case study.

    Science.gov (United States)

    Humphrey, Jaclyn

    2015-02-01

    Placenta accreta is a major cause of obstetric hemorrhage, a situation that remains the most significant cause of maternal morbidity and mortality worldwide. It is generally recognized that a previous cesarean delivery increases the risk of placenta accreta. However, the risk also increases with previous intrauterine procedures. In 2010, The Joint Commission released a sentinel event alert regarding the prevention of maternal death, which recommended the adoption of protocols to treat postpartum hemorrhage. This case study demonstrates the success of quickly initiating protocol interventions necessary to prevent disseminated intravascular coagulation and maternal mortality, while reviewing current literature on risk identification, management, and treatment of obstetric hemorrhage resulting from placenta accreta. PMID:25842631

  16. Treatment Results Of Diaphyseal Forearm Fractures With Dynamique Compression Plate A Retrospective study of 156 Cases.

    Directory of Open Access Journals (Sweden)

    Hassan BOUSSAKRI

    2016-03-01

    Full Text Available This retrospective study addresses a series of 156 cases of forearm fractures. These 156 cases were managed in the trauma-orthopedic department (B4 of Fez University Hospital, Morocco, from May 2008 till January 2013. The purpose of this study is to analyze epidemiological and clinical factors of diaphyseal forearm fractures and the results of their treatment with dynamic compression plate (DCP, as well as the complications and therapeutic errors of this surgical technique. The frequency of hospitalization in the trauma-orthopedic department was 3,96%. Ages ranged between 16 and 83, the average age was 32. 132 patients were male (85%. 90% were managed at the day of trauma. Traffic accidents were the most frequent cause in 52% patients. The fracture was in the left forearm in 65% of patients. 53% of fracture lines were in the middle third of the forearm. 38 fractures were open, and 30 were admitted for polytrauma. Osteosynthesis was performed with dynamic compression plate for all patients. In comparison with the literature, our series shows the predominance of young male patients, with traffic accidents being the cause. Osteosynthesis with dynamic compression plate remains the treatment of choice that provides satisfactory results if the accuracy in this technique was respected.

  17. Case Studies

    International Nuclear Information System (INIS)

    Proven options available to Sri Lanka for large scale electricity generation in the future are coal-fired thermal, oil-fired thermal and Nuclear. Four case studies for groups participated are indicated. Case study for group 1 is comparison of the three options by taking into consideration the capital and recurrent expenditure involved. Environmental effects of the three options are also given. Case study for group 2 is economic comparison of three renewable energy based power generation system. Case study for group 3 is based on energy conservation, efficiency, improvement and demand management. Assuming that a continuous saving of 20 MW of demand from 1996 onwards is effective two projects are suggested to achieve this result. Case study for group 4 is a feasibility study for hydro power development of the Kukule Ganga (river) in Sri Lanka. Participants are required to evaluate one of the three optional development concepts which are technically feasible

  18. Empirical Evaluation of the Proposed eXSCRUM Model-Results of a Case Study

    Directory of Open Access Journals (Sweden)

    M Rizwan Jameel Qureshi

    2011-05-01

    Full Text Available Agile models promote fast development. XP and Scrum are the most widely used agile models. This paper investigates the phases of XP and Scrum models in order to identify their potentials and drawbacks. XP model has certain drawbacks, such as not suitable for maintenance projects and poor performance for medium and large-scale development projects. Scrum model has certain limitations, such as lacked in engineering practices. Since, both XP and Scrum models contain good features and strengths but still there are improvement possibilities in these models. Majority of the software development companies are reluctant to switch from traditional methodologies to agile methodologies for development of industrial projects. A fine integration, of software management of the Scrum model and engineering practices of XP model, is very much required to accumulate the strengths and remove the limitations of both models. This is achieved by proposing an eXScrum model. The proposed model is validated by conducting a controlled case study. The results of case study show that the proposed integrated eXScrum model enriches the potentials of both XP and Scrum models and eliminates their drawbacks.

  19. Integrating the results of user research into medical device development: insights from a case study

    Directory of Open Access Journals (Sweden)

    Martin Jennifer L

    2012-07-01

    Full Text Available Abstract Background It is well established that considering users is an important aspect of medical device development. However it is also well established that there are numerous barriers to successfully conducting user research and integrating the results into product development. It is not sufficient to simply conduct user research, it must also be effectively integrated into product development. Methods A case study of the development of a new medical imaging device was conducted to examine in detail how users were involved in a medical device development project. Two user research studies were conducted: a requirements elicitation interview study and an early prototype evaluation using contextual inquiry. A descriptive in situ approach was taken to investigate how these studies contributed to the product development process and how the results of this work influenced the development of the technology. Data was collected qualitatively through interviews with the development team, participant observation at development meetings and document analysis. The focus was on investigating the barriers that exist to prevent user data from being integrated into product development. Results A number of individual, organisational and system barriers were identified that functioned to prevent the results of the user research being fully integrated into development. The user and technological aspects of development were seen as separate work streams during development. The expectations of the developers were that user research would collect requirements for the appearance of the device, rather than challenge its fundamental concept. The manner that the user data was communicated to the development team was not effective in conveying the significance or breadth of the findings. Conclusion There are a range of informal and formal organisational processes that can affect the uptake of user data during medical device development. Adopting formal decision

  20. Risk factors for femicide-suicide in abusive relationships: results from a multisite case control study.

    Science.gov (United States)

    Koziol-McLain, Jane; Webster, Daniel; McFarlane, Judith; Block, Carolyn Rebecca; Ulrich, Yvonne; Glass, Nancy; Campbell, Jacquelyn C

    2006-02-01

    The killing of women by men who then take their own lives (femicide-suicide) is the most common form of homicide-suicide. This study identified femicide-suicide risk factors in an 11-city case-control study of femicide in the United States. Perpetrator, victim, relationship, and incident characteristics were analyzed for femicide-suicide cases (n = 67) and controls (n = 356, women living in the community with nonfatal physical abuse) using logistic regression modeling. Two risk factors emerged that were unique to femicide-suicides cases compared to overall femicide risk analyses: prior perpetrator suicide threats and victims having ever been married to the perpetrator. PMID:16494130

  1. Results of case-control studies support the association between contact lens use and Acanthamoeba keratitis

    Directory of Open Access Journals (Sweden)

    Pacella E

    2013-05-01

    Full Text Available Elena Pacella,1 Giuseppe La Torre,2 Maria De Giusti,2 Chiara Brillante,1 Anna Maria Lombardi,2 Gianpaolo Smaldone,1 Tommaso Lenzi,1 Fernanda Pacella11Department of Sense Organs, Faculty of Medicine and Dentistry, Sapienza University of Rome, Italy; 2Department of Public Health and Infectious Diseases, Faculty of Pharmacy and Medicine, Sapienza University of Rome, ItalyBackground: Acanthamoeba keratitis (AK is ever more frequently reported in industrialized countries. The loss of the corneal surface integrity consequent to secondary microtrauma produced by the use of contact lens (CL favors the penetration of the parasite into the corneal tissue.Objectives: A scientific review was performed to investigate the association of CL wear as an Acanthamoeba keratitis (AK risk factor.Methods: A computerized screening of 7834 Medline articles (4623 from PubMed; 3211 from Scopus used a strict selection criteria of case-control studies involving CL wear and/or trauma.Results: The search yielded five case-control studies published from 1995 to 2012. All studies included showed a statistically significant positive association between AK and CL use, with a combined odds ratio (OR of 10.21 (95%, confidence intervals [CI]; 3.57–27.64.Statistical analysis: All studies included showed a statistically significant positive association between AK and CL use, though with differing OR values.Conclusion: Though rare, AK should be held in higher consideration when ophthalmologists are faced with CL users exhibiting simplex-like lesions associated with circular stromal infiltrates and disproportionate ocular pain in respect to the objective clinical picture.Keywords: keratitis, contact lens, Acanthamoeba

  2. Social status and cardiovascular disease: a Mediterranean case. Results from the Italian Progetto CUORE cohort study

    Directory of Open Access Journals (Sweden)

    Pilotto Lorenza

    2010-09-01

    Full Text Available Abstract Background Social factors could offer useful information for planning prevention strategy for cardiovascular diseases. This analysis aims to explore the relationship between education, marital status and major cardiovascular risk factors and to evaluate the role of social status indicators in predicting cardiovascular events and deaths in several Italian cohorts. Methods The population is representative of Italy, where the incidence of the disease is low. Data from the Progetto CUORE, a prospective study of cohorts enrolled between 1983-1997, were used; 7520 men and 13127 women aged 35-69 years free of previous cardiovascular events and followed for an average of 11 years. Educational level and marital status were used as the main indicators of social status. Results About 70% of the studied population had a low or medium level of education (less than high school and more than 80% was married or cohabitating. There was an inverse relationship between educational level and major cardiovascular risk factors in both genders. Significantly higher major cardiovascular risk factors were detected in married or cohabitating women, with the exception of smoking. Cardiovascular risk score was lower in married or cohabitating men. No relationship between incidence of cardiac events and the two social status indicators was observed. Cardiovascular case-fatality was significantly higher in men who were not married and not cohabitating (HR 3.20, 95%CI: 2.21-4.64. The higher cardiovascular risk observed in those with a low level of education deserves careful attention even if during the follow-up it did not seem to determine an increase of cardiac events. Conclusions Preventive interventions on cardiovascular risk should be addressed mostly to people with less education. Cardiovascular risk score and case-fatality resulted higher in men living alone while cardiovascular factors were higher in women married or cohabitating. Such gender differences seem

  3. Comparing Simulation Results with Traditional PRA Model on a Boiling Water Reactor Station Blackout Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Zhegang Ma; Diego Mandelli; Curtis Smith

    2011-07-01

    A previous study used RELAP and RAVEN to conduct a boiling water reactor station black-out (SBO) case study in a simulation based environment to show the capabilities of the risk-informed safety margin characterization methodology. This report compares the RELAP/RAVEN simulation results with traditional PRA model results. The RELAP/RAVEN simulation run results were reviewed for their input parameters and output results. The input parameters for each simulation run include various timing information such as diesel generator or offsite power recovery time, Safety Relief Valve stuck open time, High Pressure Core Injection or Reactor Core Isolation Cooling fail to run time, extended core cooling operation time, depressurization delay time, and firewater injection time. The output results include the maximum fuel clad temperature, the outcome, and the simulation end time. A traditional SBO PRA model in this report contains four event trees that are linked together with the transferring feature in SAPHIRE software. Unlike the usual Level 1 PRA quantification process in which only core damage sequences are quantified, this report quantifies all SBO sequences, whether they are core damage sequences or success (i.e., non core damage) sequences, in order to provide a full comparison with the simulation results. Three different approaches were used to solve event tree top events and quantify the SBO sequences: “W” process flag, default process flag without proper adjustment, and default process flag with adjustment to account for the success branch probabilities. Without post-processing, the first two approaches yield incorrect results with a total conditional probability greater than 1.0. The last approach accounts for the success branch probabilities and provides correct conditional sequence probabilities that are to be used for comparison. To better compare the results from the PRA model and the simulation runs, a simplified SBO event tree was developed with only four

  4. Seven to twelve year results with Versys ET cementless stem. A retrospective study of 225 cases.

    Science.gov (United States)

    D'Angelo, Fabio; Murena, Luigi; Vulcano, Ettore; Zatti, Giovanni; Cherubino, Paolo

    2010-01-01

    A retrospective review was conducted to evaluate the mid-term results (8.5 years follow-up) of the Versys ET stem (Zimmer, Warsaw, Indiana, USA). From 1995 to 2000, 225 total hip arthroplasties (THA) were performed using this device. All patients were evaluated clinically by the Harris Hip Score, and radiographically. The Hip Score increased from 54 preoperatively to 97 points postoperatively. The stem displayed a varus alignment between 5 degrees and 10 degrees in 17 cases without any clinical consequences (HHS 96.8). We recorded one case of septic loosening and one case of aseptic loosening. The stability of the stem was radiographically evaluated according to Engh's criteria, confirming bone ongrowth in all other cases. PMID:20235069

  5. Malnutrition and Childhood Disability in Turkana, Kenya: Results from a Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Hannah Kuper

    Full Text Available Children with disabilities may be particularly vulnerable to malnutrition, as a result of exclusions and feeding difficulties. However, there is limited evidence currently available on this subject.A population-based case-control study was conducted in Turkana County, Kenya, between July and August 2013. Key informants in the community identified children aged 6 months to 10 years who they believed may have a disability. These children were screened by a questionnaire (UNICEF-Washington Group and assessed by a paediatrician to confirm whether they had a disability and the type. Two controls without disabilities were selected per case: A sibling control (sibling nearest in age and a neighbourhood control (nearest neighbour within one year of age. The caregiver completed a questionnaire on behalf of the child (e.g. information on feeding, poverty, illness, education, and anthropometric measures were taken. We undertook multivariable logistic and linear regression analyses to estimate the relationship between disability and malnutrition.The study included 311 cases with disabilities, 196 sibling controls and 300 neighbour controls. Children with disabilities were more likely to report a range of feeding difficulties. They were 1.6-2.9 times more likely to have malnutrition in comparison to neighbour controls or family controls, including general malnutrition (low weight for age, stunting (low height for age, low body mass index (BMI or low mid upper arm circumference (MUAC for age. Children with disabilities were almost twice as likely to have wasting (low weight for height in comparison to neighbour controls (OR = 1.9, 95% CI 1.1-3.2, but this difference was not apparent compared with siblings (OR = 1.5, 95% CI 0.8-2.7. Children with disabilities also faced other exclusions. For instance those aged 5+ were much more likely not to attend school than neighbour controls (OR = 8.5, 95% CI 4.3-16.9.Children with disabilities were particularly

  6. Immediate Results of Omentopexy in Perforated Duodenal Ulcer: A Study of 186 Cases

    Directory of Open Access Journals (Sweden)

    Nishikant Gujar*, Jilani Awati, Sajid Mudhol, Salahuddin Contractor, Ravikumar Choudhari and Sushila Garag

    2012-01-01

    Full Text Available Aim of the Study: The study was conducted to determine short term results in view of associated diseases, complications, mortality and hospital stay in patients with duodenal ulcer perforation treated by omentopexy. Main Findings: Age of patients range from 15 to 85 years; mean age was 45.58 years; In all cases, perforation was present on the anterior surface of the first part of the duodenum. Size of perforation varied from 0.3 to 2.5 cm. 50 (26.88% patients had co-existing illnesses. Among the complications, the commonest complication was wound infection. 53 patients (28.49% had wound infection, 45 patients (24.19% had lung infections, 5 patients (2.68% had re-perforation of the ulcer, 2 patients (1.07% had burst abdomens, 2 patients (1.07% had pelvic abscesses and 1 patient (0.53% had DIC. Mortality was 18 patients(9.67%. Median hospital stay was 10 days. Conclusion: Perforation is one of the most catastrophic complications of peptic ulcer. In spite of modern advances in surgical, anesthetic and ancillary facilities, it still assumes life threatening dimensions. Omentopexy is a simple and safe procedure. The most important factors predisposing to complications are delay in admission to the hospital, associated diseases and shock on admission. Mortality and morbidity can be reduced by early admission, prompt resuscitation, treatment of associated diseases, early surgical intervention and prophylaxis of complications.

  7. Blending vertical and web results: A case study using video intent

    NARCIS (Netherlands)

    D. Lefortier; P. Serdyukov; F. Romanenko; M. de Rijke

    2014-01-01

    Modern search engines aggregate results from specialized verticals into the Web search results. We study a setting where vertical and Web results are blended into a single result list, a setting that has not been studied before. We focus on video intent and present a detailed observational study of

  8. Handling uncertainty in relation extraction: a case study on tennis tournament results extraction from tweets

    NARCIS (Netherlands)

    Verburg, J.; Habib, M. B.; Keulen, M. van

    2015-01-01

    Relation extraction involves different types of uncertainty due to the imperfection of the extraction tools and the inherent ambiguity of unstructured text. In this paper, we discuss several ways of handling uncertainties in relation extraction from social media. Our study case is to extract tennis

  9. How to build successful city brands? – Comparing results from 11 case studies

    OpenAIRE

    Dahlström, Tiia; Poikkijoki, Anna-Paulina

    2014-01-01

    This thesis is a portfolio thesis, which means in this case, that some of the parts are collected from already existing thesises. The first part of this thesis, which is the theoretical background (chapters 2-5) existed before this thesis. Chapter 1 from the part I is written by the authors of this thesis. The second part of this thesis, methodologies and case studies, chapters 6 and 7 are written completely by the authors of this thesis. The objective of this thesis is to find the succes...

  10. Lung cancer risk and welding--preliminary results from an ongoing case-control study.

    Science.gov (United States)

    Jöckel, K H; Ahrens, W; Bolm-Audorff, U

    1994-06-01

    In a hospital-based case-control study, 391 male cases or primary lung cancer and the same number of controls--matched by sex, age, and region--were personally interviewed for their job and smoking histories. The data reported reflect the midpoint of a study aiming at a total of 1,000 cases. One objective of the study was to assess confounding by asbestos exposure in what was thought to be a welding-associated risk. While the odds ratios (OR) increased steeply with cumulative exposure to tobacco smoke and were raised also for lifelong asbestos exposure of over 4,100 working hours (OR = 1.91), the effect of welding exposure was reduced after adjustment for smoking and exposure to asbestos. Furthermore, no consistent dose-response relationship could be shown in relation to welding hours. Therefore the present study supports the hypothesis that some, if not all, of the excess risk of welders observed in the literature may be due to the exposure to asbestos. The finding that the subgroup of employees in the aircraft industry showed an increased odds ratio of 2.14 after adjustment for smoking and exposure to asbestos deserves further attention. This suggests the need for further research on the role of berryllium-containing alloys, which has been suggested by other authors.

  11. Towards an Integrated Approach to Crowd Analysis and Crowd Synthesis: a Case Study and First Results

    CERN Document Server

    Bandini, Stefania; Vizzari, Giuseppe

    2013-01-01

    Studies related to crowds of pedestrians, both those of theoretical nature and application oriented ones, have generally focused on either the analysis or the synthesis of the phenomena related to the interplay between individual pedestrians, each characterised by goals, preferences and potentially relevant relationships with others, and the environment in which they are situated. The cases in which these activities have been systematically integrated for a mutual benefit are still very few compared to the corpus of crowd related literature. This paper presents a case study of an integrated approach to the definition of an innovative model for pedestrian and crowd simulation (on the side of synthesis) that was actually motivated and supported by the analyses of empirical data acquired from both experimental settings and observations in real world scenarios. In particular, we will introduce a model for the adaptive behaviour of pedestrians that are also members of groups, that strive to maintain their cohesion...

  12. Associations of depression and depressive symptoms with preeclampsia: results from a Peruvian case-control study

    OpenAIRE

    Garcia Pedro; Lam Nelly; Sanchez Sixto E; Qiu Chunfang; Williams Michelle A

    2007-01-01

    Abstract Background Preeclampsia involves endothelial dysfunction, platelet dysfunction/activation and sympathetic over-activity similar to cardiovascular disorders (CVD). Depression, an independent risk factor for progression of CVD, was found to be associated with an increased risk of preeclampsia among Finnish women. We examined the relation between depression/depressive symptoms and preeclampsia risk among Peruvian women. Methods The study included 339 preeclamptic cases and 337 normotens...

  13. Occupation and skin cancer: the results of the HELIOS-I multicenter case-control study

    Directory of Open Access Journals (Sweden)

    Gafà Lorenzo

    2007-07-01

    Full Text Available Abstract Background Non-melanoma skin cancer (NMSC is the most frequent tumour among Caucasian populations worldwide. Among the risk factors associated with this tumour, there are host-related factors and several environmental agents. A greater likelihood of high exposure to physical agents (with the exception of solar radiation and chemical agents depends on the work setting. Our objective is to evaluate the role of occupational exposures in NMSC, with special emphasis on risk factors other than solar radiation and skin type. Methods We analysed 1585 cases (1333 basal cell carcinoma (BCC and 183 squamous cell carcinoma (SCC and 1507 controls drawn from the Helios-I multicenter study. Odds ratios (OR and 95% confidence intervals (CI were estimated using logistic regression mixed models. Results For NMSC as a whole (both histological types, miners and quarrymen, secondary education teachers, and masons registered excess risk, regardless of exposure to solar radiation and skin type (OR 7.04, 95% CI 2.44–20.31; OR 1.75, 95% CI 1.05–2.89 and OR 1.54, 95% CI 1.04–2.27, respectively. Frequency of BCC proved higher among railway engine drivers and firemen (OR 4.55; 95% CI 0.96–21.57, specialised farmers (OR 1.65; 95% CI 1.05–2.59 and salesmen (OR 3.02; 95% CI 1.05–2.86, in addition to miners and quarrymen and secondary education teachers (OR 7.96; 95% CI 2.72–23.23 and OR 1.76; 95% CI 1.05–2.94 respectively. The occupations that registered a higher risk of SCC (though not of BCC were those involving direct contact with livestock, construction workers not elsewhere classified (OR 2.95, 95% CI 1.12–7.74, stationary engine and related equipment operators not elsewhere classified (OR 5.31, 95% CI 1.13–21.04 and masons (OR 2.55, 95% CI 1.36–4.78. Conclusion Exposure to hazardous air pollutants, arsenic, ionizing radiations and burns may explain a good part of the associations observed in this study. The Helios study affords an

  14. Sea urchin puncture resulting in PIP joint synovial arthritis: case report and MRI study.

    Science.gov (United States)

    Liram, N; Gomori, M; Perouansky, M

    2000-01-01

    Of the 600 species of sea urchins, approximately 80 may be venomous to humans. The long spined or black sea urchin, Diadema setosum may cause damage by the breaking off of its brittle spines after they penetrate the skin. Synovitis followed by arthritis may be an unusual but apparently not a rare sequel to such injury, when implantation occurs near a joint. In this case report, osseous changes were not seen by plain x-rays. Magnetic resonance imaging (MRI) was used to expose the more salient features of both soft tissue and bone changes of black sea urchin puncture injury 30 months after penetration. In all likelihood, this type of injury may be more common than the existing literature at present suggests. It is believed to be the first reported case in this part of the world as well as the first MRI study describing this type of joint pathology. Local and systemic reactions to puncture injuries from sea urchin spines have been described previously. These may range from mild, local irritation lasting a few days to granuloma formation, infection and on occasions systemic illness. The sea urchin spines are composed of calcium carbonate with proteinaceous covering. The covering tends to cause immune reactions of variable presentation. There are only a handful of reported cases with sea urchin stings on record, none of them from the Red Sea. However, this condition is probably more common than is thought and can present difficulty in diagnosis. In this case report, the inflammation responded well to heat treatment, mobilization and manipulation of the joint in its post acute and chronic stages. As some subtle changes in soft tissues and the changes in bone were not seen either on plain x-rays or ultrasound scan, gadolinium-enhanced MRI was used to unveil the marked changes in the joint.

  15. Technical Approach and Results from the Fuels Pathway on an Alternative Selection Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Bob Youngblood; Curtis Smith

    2013-09-01

    The report presents a detailed plan for conducting case studies to characterize probabilistic safety margins associated with different fuel cladding types in a way that supports a valid comparison of different fuels' performance. Recent work performed in other programs is described briefly and used to illustrate the challenges posed by characterization of margin in a probabilistic way. It is additionally pointed out that consistency of evaluation of performance across different cladding types is not easy to assure; a process for achieving the needed consistency is described.

  16. Public participation in energy facility siting. Part 1; Case study results

    Energy Technology Data Exchange (ETDEWEB)

    Whitlatch, E.E. (Ohio State Univ., Columbus, OH (USA). Dept. of Civil Engineering); Aldrich, J.A. (McKee Inc., Annandale, VA (US)); Cristo, M. (Packard Electric, Div. of General Motors Corp., Warren, OH (US))

    1990-08-01

    The objective of this paper is to determine to what extent public participation has been effective in influencing recent energy-facility siting (EFS) decisions for nuclear and coal-fired power plants in the Ohio River Basin. Licensing requirements, review procedures, and criteria were studied for six basin states, along with utility-siting criteria and siting methodologies. Six case study power plants (four coal-fired and two nuclear) were investigated in detail. It is concluded that the current regulatory/adjudicatory EFS process is not conducive to meaningful public participation for a wide range of reasons, which include: lack of public involvement during the crucial early site screening stage; lack of public information during the long draft environmental impact statement (DEIS) stage; the negative effect on public trust caused by site purchase and limited site work before issuance of the DEIS; and siting methodologies that heavily emphasize technological criteria.

  17. A Possible Association between Melanoma and Prostate Cancer. Results from a Case-Control-Study

    Directory of Open Access Journals (Sweden)

    Alina Goldenberg

    2015-04-01

    Full Text Available Melanoma and prostate cancer are the fifth and first most common cancers in men within the United States, respectively. The association between the two cancers lies in the mutual androgen-dependence. However, the relationship between prostate cancer history and melanoma development remains to be further elucidated. We aim to determine the odds of history of prostate cancer among men with melanoma as compared to time-frame, clinic, and provider-matched controls without melanoma within a single academic surgical center. We present a case-control study comparing men treated for melanoma and non-melanoma cancer by a single provider between 2010 and 2014 within an academic dermatologic surgical center. Overall, there were nine cases of prostate cancer among the melanoma group and two cases amongst the controls—a statistically significant difference in both uni- and multivariable analyses (p = 0.057 [95% CI 1, 23.5], p = 0.042 [95% CI 1.1, 129], respectively. Body mass index, alcohol use, and skin type II were significant risk factors for melanoma (p = 0.011 [95% CI 1, 1.3], 0.005 [95% CI 1.4, 7], 0.025 [95% CI 1.1, 3.3], respectively. There were more immunosuppressed controls (p = 0.002; however, the melanoma patients had a significantly longer duration of immunosuppression (11.6 vs. 1.9 years, p < 0.001 [95% CI 0.03, 0.5]. Melanoma screenings for men should include questions on prostate cancer history. Prostate cancer patients may benefit from more frequent and comprehensive melanoma screening.

  18. Risk factors for different phenotypes of hypospadias: results from a Dutch case-control study

    NARCIS (Netherlands)

    Rooij, I.A.L.M. van; Zanden, L.F.M. van der; Brouwers, M.M.; Knoers, N.V.A.M.; Feitz, W.F.J.; Roeleveld, N.

    2013-01-01

    WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: The various phenotypes of hypospadias may result from disturbances of dissimilar embryonic processes in different time windows, suggesting aetiological heterogeneity; however, only a few studies have investigated the risk factors for the dif

  19. Reporting individual results for biomonitoring and environmental exposures: lessons learned from environmental communication case studies.

    Science.gov (United States)

    Brody, Julia Green; Dunagan, Sarah C; Morello-Frosch, Rachel; Brown, Phil; Patton, Sharyle; Rudel, Ruthann A

    2014-05-26

    Measurement methods for chemicals in biological and personal environmental samples have expanded rapidly and become a cornerstone of health studies and public health surveillance. These measurements raise questions about whether and how to report individual results to study participants, particularly when health effects and exposure reduction strategies are uncertain. In an era of greater public participation and open disclosure in science, researchers and institutional review boards (IRBs) need new guidance on changing norms and best practices. Drawing on the experiences of researchers, IRBs, and study participants, we discuss ethical frameworks, effective methods, and outcomes in studies that have reported personal results for a wide range of environmental chemicals. Belmont Report principles and community-based participatory research ethics imply responsibilities to report individual results, and several recent biomonitoring guidance documents call for individual reports. Meaningful report-back includes contextual information about health implications and exposure reduction strategies. Both narrative and graphs are helpful. Graphs comparing an individual's results with other participants in the study and benchmarks, such as the National Exposure Report, are helpful, but must be used carefully to avoid incorrect inferences that higher results are necessarily harmful or lower results are safe. Methods can be tailored for specific settings by involving participants and community members in planning. Participants and researchers who have participated in report-back identified benefits: increasing trust in science, retention in cohort studies, environmental health literacy, individual and community empowerment, and motivation to reduce exposures. Researchers as well as participants gained unexpected insights into the characteristics and sources of environmental contamination. Participants are almost universally eager to receive their results and do not regret getting

  20. RSG Deployment Case Testing Results

    Energy Technology Data Exchange (ETDEWEB)

    Owsley, Stanley L.; Dodson, Michael G.; Hatchell, Brian K.; Seim, Thomas A.; Alexander, David L.; Hawthorne, Woodrow T.

    2005-09-01

    The RSG deployment case design is centered on taking the RSG system and producing a transport case that houses the RSG in a safe and controlled manner for transport. The transport case was driven by two conflicting constraints, first that the case be as light as possible, and second that it meet a stringent list of Military Specified requirements. The design team worked to extract every bit of weight from the design while striving to meet the rigorous Mil-Spec constraints. In the end compromises were made primarily on the specification side to control the overall weight of the transport case. This report outlines the case testing results.

  1. Viral Hemorrhagic Fever Cases in the Country of Georgia: Acute Febrile Illness Surveillance Study Results

    Science.gov (United States)

    Kuchuloria, Tinatin; Imnadze, Paata; Chokheli, Maiko; Tsertsvadze, Tengiz; Endeladze, Marina; Mshvidobadze, Ketevan; Clark, Danielle V.; Bautista, Christian T.; Fadeel, Moustafa Abdel; Pimentel, Guillermo; House, Brent; Hepburn, Matthew J.; Wölfel, Silke; Wölfel, Roman; Rivard, Robert G.

    2014-01-01

    Minimal information is available on the incidence of Crimean–Congo hemorrhagic fever (CCHF) virus and hantavirus infections in Georgia. From 2008 to 2011, 537 patients with fever ≥ 38°C for ≥ 48 hours without a diagnosis were enrolled into a sentinel surveillance study to investigate the incidence of nine pathogens, including CCHF virus and hantavirus. Of 14 patients with a hemorrhagic fever syndrome, 3 patients tested positive for CCHF virus immunoglobulin M (IgM) antibodies. Two of the patients enrolled in the study had acute renal failure. These 2 of 537 enrolled patients were the only patients in the study positive for hantavirus IgM antibodies. These results suggest that CCHF virus and hantavirus are contributing causes of acute febrile syndromes of infectious origin in Georgia. These findings support introduction of critical diagnostic approaches and confirm the need for additional surveillance in Georgia. PMID:24891463

  2. Comparing the Resulted Strategies from the SWOT and the SPACE (Electricity Company as Case Study

    Directory of Open Access Journals (Sweden)

    Abolfazl Sherafat

    2013-04-01

    Full Text Available The present study was aimed to compare the implementation of two models in terms of strategic planning. In order to this, firstly, several field studies have been done in terms of the SWOT and the SPACE analysis. In the next step, a team of the meddle and senior managers that have studied in terms of SWOT analysis seek to identify the organization’s strengths, weaknesses, opportunities, and threats and then develop their related strategies. They also develop and indicate the SPACE questionnaire. Based on the results of this questionnaire and determining the organization’s strategic position, they strive to develop the appropriate strategies. Finally, the strategies that have been derived from these models were compared to each other and their strengths and weaknesses were analyzed.

  3. Revision Stapedotomy : Operative Findings and Hearing Results. A Prospective Study of 652 Cases From the Otology-Neurotology Database

    NARCIS (Netherlands)

    Vincent, Robert; Rovers, Maroeska; Zingade, Narayan; Oates, John; Sperling, Neil; Deveze, Arnaud; Grolman, Wilko

    2010-01-01

    Objective: To identify the causes of failure of primary stapes surgery and to evaluate the hearing results of revision stapes surgery in a consecutive series of 652 cases. Study Design: Prospective nonrandomized clinical study. Setting: Tertiary referral center. Patients: Six hundred thirty-four pat

  4. Use of dairy products, lactose, and calcium and risk of ovarian cancer - results from a Danish case-control study

    DEFF Research Database (Denmark)

    Faber, Mette Tuxen; Jensen, Allan; Søgaard, Marie;

    2012-01-01

    A number of epidemiological studies have examined the association between use of dairy products and risk of ovarian cancer, but results are conflicting. Using data from a large Danish population-based case-control study we here further examined the association between dairy consumption, lactose...

  5. Lecturers’ Commitment And Students’ Academic Achievement: Case Study From Existing Teaching Evaluation Result (TER

    Directory of Open Access Journals (Sweden)

    Tengku Noorainun Tengku Shahdan

    2012-09-01

    Full Text Available This study reported herein is the used of TER as the basis to ascertain if the commitment of the lecturers can lead to academic excellence of the students.  The TER is comprised of questionnaires in which the foundation students are the respondents (N=433 in assessing the courses as well as the lecturers.  The performances of the students in the form of final exam grades are also used. The respondents were comprised of 85% Indian, 10% Malay and 5% Chinese.  There are more than 30% of the students who have obtained a grade of A- and better, the TER was < 80%.  Due to the limitation and the unavailability of matching each student to their evaluation towards the lecturers, the results presented above is weakly conclusive. It is recommended that future research in similar areas to incorporate the matching of students be made with the lecturers to obtain reliable and conclusive result.

  6. Implications for advanced safeguards derived from PR&PP case study results

    Energy Technology Data Exchange (ETDEWEB)

    Boyer, Brian D [Los Alamos National Laboratory

    2009-01-01

    The proliferation resistance and physical protection (PR and PP) working group produced a case study on the Example Sodium Fast Reactor (ESFR). The ESFR is a hypothetical nuclear energy system consisting of four sodium-cooled fast reactors of medium size collocated with an on-site dry fuel storage facility and a spent fuel reprocessing facility using pyroprocessing technology. This study revealed how safeguards would be applied at such site consisting of integrated multiple fuel cycle facilities and the implications of what safeguards technology and safeguards concepts would need to be adapted and developed to safeguard successfully this Generation IV nuclear energy system concept. The major safeguards concepts driving our safeguards analysis are timeliness goals and material quantity goals. Because the fresh transuranic (TRU) fuel to be produced in the ESFR fuel fabrication facility contains plutonium, the ESFR will be reprocessing, using in the reactor, and storing material on site that will have IAEA defined 'direct-use material' in it with stringent timeliness goals and material quantity goals that drive the safeguards implementation. Specifically, the TRU fresh fuel, pyroprocessing in process material, LWR spent fuel sent to the ESFR, and TRU spent fuel will contain plutonium. This material will need to be verified at interim intervals four times per year because the irradiated direct-use material, as defined previously, has three-month timeliness goals and 8 kg material quantity goals for plutonium. The TRU in-process material is, of course, irradiated direct-use material as defined by the IAEA. Keeping the plutonium and uranium together with TRu products should provide a radiation barrier. this radiation barrier slows down the ability to reprocess the fuel. Furthermore, the reprocessing technique, if it has some intrinsic proliferation resistance, will need major modifications to be able to separate plutonium from the uranium and TRU mixture. The

  7. Carbon savings resulting from the cooling effect of green areas: A case study in Beijing

    International Nuclear Information System (INIS)

    Green areas cool the climate of a city, reduce the energy consumption caused by the urban heat island (UHI) effect, and bring along carbon savings. However, the calculation of carbon savings due to the cooling effect of green areas is still not well understood. We have used a Landsat Enhanced Thematic Mapper Plus (ETM+) image of Beijing, to identify the cooled areas, compute the possible energy used to maintain the temperature differences between cooled areas and their surrounding heated areas, and calculate the carbon savings owing to the avoidance of energy use. Results show that a total amount of 14315.37 tons carbon savings was achieved in the study area and the amount was related to the biomass, the size and the shape of green areas. These results demonstrate the importance of carbon savings resulting from green areas' cooling effect. - Highlights: → We provide an integral equation for the calculation of energy conservation and carbon savings. → We show that carbon savings is partly influenced by green areas' features. → A strong correlation between biomass, size and shape of green areas and carbon savings. - An integral equation for the calculation of energy conservation and carbon savings; Showing that carbon savings is partly influenced by green areas' features.

  8. Results based management in Albanian local governments. Case study municipality of Korca

    Directory of Open Access Journals (Sweden)

    Eva Dhimitri

    2012-12-01

    Full Text Available Public Management has been a constant concern for all politicians and public administrators at all levels of governance in Albania. Increase of public demand for higher accountability, efficiency in the administration of public goods and services is now challenging the traditional means of governance by so aiming tangible results in the public management. Results Based Management (RBM is a new approach in the public management, a practice already developed in the western countries. RBM is defined as an approach that integrates in one whole instrument the strategies, human resources, processes and their evaluation, with the aim of improving decision-making, transparency, and accountability of public institutions. This study makes an effort to approximate and clarify as simply as possible such a management scheme which remains a relatively new approach for Albania and especially for local governance stakeholders. RBM is not only a planning-monitoring -evaluation tool but also a model that can facilitate the activity and development of Local Government Units in order for them to improve their “product/services”. From empirical data deriving from this prior assessment it results that municipality of Korca in Albania have the willingness and the institutional and technical capacities, though very fragmented and not integrated in one whole clear model, to embrace the RBM as a new approach in their institution’s management.

  9. Implementing a continuum of care model for older people - results from a Swedish case study

    Directory of Open Access Journals (Sweden)

    Anna Duner

    2011-11-01

    Full Text Available Introduction: There is a need for integrated care and smooth collaboration between care-providing organisations and professions to create a continuum of care for frail older people. However, collaboration between organisations and professions is often problematic. The aim of this study was to examine the process of implementing a new continuum of care model in a complex organisational context, and illuminate some of the challenges involved. The introduced model strived to connect three organisations responsible for delivering health and social care to older people: the regional hospital, primary health care and municipal eldercare.Methods: The actions of the actors involved in the process of implementing the model were understood to be shaped by the actors' understanding, commitment and ability. This article is based on 44 qualitative interviews performed on four occasions with 26 key actors at three organisational levels within these three organisations.Results and conclusions: The results point to the importance of paying regard to the different cultures of the organisations when implementing a new model. The role of upper management emerged as very important. Furthermore, to be accepted, the model has to be experienced as effectively dealing with real problems in the everyday practice of the actors in the organisations, from the bottom to the top.

  10. [Lung cancer and cigarette smoking in women. (Results of a case control study)].

    Science.gov (United States)

    Vutuc, C

    1982-08-01

    Smoking habits of 297 female lung cancer patients (Kreyberg I: 202, Kreyberg II: 95) and 580 controls were analyzed. In addition tar exposures (TE) were calculated. Calculation of TE includes amount of consumptions, duration and the tar yields of all cigarette brands ever smoked. These are significant more smokers among patients (63%) and patients with a K I tumor (80%) compared to the controls (21%); K II: 29%. All patients and patients with a K I tumor had a significant longer smoking career (39.3 years; 39.6 years) and a higher tar exposure (TE = 1767; TE - 1810) compared to the controls (31.9 years, TE = 1146). K II: 37.4 years, TE = 1508. Lung cancer risks (adj. for TE) and population attributable risks (PAR) were: all age groups R = 7.3*, PAR = 54%; less than 40 years R = 1.1, PAR = 3%; 41-50 years R = 4.2*, PAR = 42% ; 51-60 years R = 7.6*, PAR = 62%; 61-70 years R = 7.8*, PAR = 54%; greater than 71 years R = 8.0*, PAR = 55%. Lung cancer risks (adj. for age) in relation to tar exposure and attributable risks (AR) were: TE less than 500: all cases R = 1.5, AT = 34% (KIR = 2.9, K II R = 0.8); TE 501-1000: all cases R = 4.2*, AR = 76% (KIR = 9.9*, K II R - 1.1): TE 1001-2000: all cases R = 12.1*, AR = 92% (KIR = 27.2*, K II R = 2.6**); TE 2001-3000: all cases R = 11.1*, AR = 91% (KIR = 25.2*, K II R = 2.0); TE greater than 3001: all cases R = 13.0*, AR = 92% (KIR = 29.3*, K II R = 3.3). These is a significant increase of risk of cigarette smokers beyond a TE of 501, which could be identified as a sort of critical exposure. There is a pronounced dose response relationship between cigarette smoking in relation to TE and lung cancer risk as concerning K I tumors but not KII tumors. Lung cancer risks in relation to age began smoking: less than 19 years R = 7.8*; 19 years and above R = 6.5*. *P less than 1%, **P less than 5%. PMID:7148206

  11. The Results of Biplanar Distal Femoral Osteotomy; A Case Series Study

    Directory of Open Access Journals (Sweden)

    Abolfazl Bagherifard

    2015-01-01

    Full Text Available Background:  Distal femur wedge osteotomies for varus or valgus alignment of the lower extremity could be done in either uniplanar or biplanar fashion.Union time and stability of the osteotomy site has been considered important in this anatomic region. In this study, clinical and radiographic findings of biplane distal femur osteotomy were reported. Methods: Clinical, functional, and radiological findings of eight patients (10 kneesunderwent biplane distal femur osteotomy were evaluated. Visual analogue score (VAS and Lysholm-Tegner knee score were used for the assessment of pain and function before and three months after surgery. Results:  In this study, eight patients were included. All patients were female. The mean age was 28±6.3. The mean pre-operativemechanical anglewas 8.7±2.2˚and the post-operativeangle was 1.4±0.53˚ in patients with valgus alignment whileit was 7.0±1.0˚preoperatively and 0.66±1.2˚ postoperatively in patients with varus alignment. The mean lateral distal femoral angle (LDFAwas 85±8.0˚ before surgery and was 88±1.3˚ after surgery. According to Lysholm- Tegner knee score, in the post-operative visit, sixknees were good and four were excellent. The mean union time was 9.2±2.3 weeks.   Conclusions:  Biplane distal femur osteotomy is a reliable technique that creates larger surfaces and more stability at the osteotomy site with further rapid union. 

  12. Computer use and ulnar neuropathy: results from a case-referent study

    DEFF Research Database (Denmark)

    Andersen, JH; Frost, P.; Fuglsang-Frederiksen, A.;

    2012-01-01

    -2007. We mailed a questionnaire to 546 patients with ulnar neuropathy, 633 patients with ulnar neuropathy-like symptoms, and three community referents per case, matched on sex, age, and primary care centre. From a Job Exposure Matrix we extracted estimates of daily hours of computer use. The analysis...... neuropathy (OR=2.16, 95 % CI; 1.06-4.44).The two outcomes were not associated with daily hours of computer use. Findings suggested specific effects of pressure on the elbow, and might be an explanation for the overweight of left-sided outcomes in this primarily right-handed group. Preventive efforts would...

  13. Retrospective study of sonographic findings in bone involvement associated with rotator cuff calcific tendinopathy: preliminary results of a case series

    Directory of Open Access Journals (Sweden)

    Marcello H. Nogueira-Barbosa

    2015-12-01

    Full Text Available Abstract Objective: The present study was aimed at investigating bone involvement secondary to rotator cuff calcific tendonitis at ultrasonography. Materials and Methods: Retrospective study of a case series. The authors reviewed shoulder ultrasonography reports of 141 patients diagnosed with rotator cuff calcific tendonitis, collected from the computer-based data records of their institution over a four-year period. Imaging findings were retrospectively and consensually analyzed by two experienced musculoskeletal radiologists looking for bone involvement associated with calcific tendonitis. Only the cases confirmed by computed tomography were considered for descriptive analysis. Results: Sonographic findings of calcific tendinopathy with bone involvement were observed in 7/141 (~ 5% patients (mean age, 50.9 years; age range, 42-58 years; 42% female. Cortical bone erosion adjacent to tendon calcification was the most common finding, observed in 7/7 cases. Signs of intraosseous migration were found in 3/7 cases, and subcortical cysts in 2/7 cases. The findings were confirmed by computed tomography. Calcifications associated with bone abnormalities showed no acoustic shadowing at ultrasonography, favoring the hypothesis of resorption phase of the disease. Conclusion: Preliminary results of the present study suggest that ultrasonography can identify bone abnormalities secondary to rotator cuff calcific tendinopathy, particularly the presence of cortical bone erosion.

  14. What factors play a role in preventing self-immolation?Results from a case-control study in Iran

    Directory of Open Access Journals (Sweden)

    Hosein Karim

    2015-07-01

    Full Text Available Abstract: Background: To investigate factors related to prevention of self-immolation in west of Iran. Methods: In a case-control study, 30 consecutive cases of deliberate self-inflicted burns admitted to the regional burn center (Imam Khomeini hospital in Kermanshah province, Iran were compared with controls selected from the community and matched by sex, age,district-county of residence, and rural vs urban living environment. The following characteristics relevant to preventing self immolation were collected from all cases and controls: main domestic fuel used in the household, awareness about complications of burn injuries, and use of counseling services. Results: Descriptive analyses revealed that kerosene was the main domestic fuel in the household for 83% of cases. Not surprisingly, the main means of self-immolation in 93% of the patients was kerosene, with other fuels such as petrol and domestic gas used in remaining cases. The majority of cases and controls were aware of the potential complications of burn injuries. Use of counseling services was more common in controls. Conclusions: All three aspects of preventing self-immolation – having kerosene and other fuels in the home, being aware of the complications of burn injuries, and using counseling services were present in both the cases and controls. This suggests a large portion of residents in rural Iran are potential self-immolation victims. Increasing preventive strategies may reduce risk of suicide by self-immolation.

  15. Clinical utility of in-socket residual limb volume change measurement: Case study results

    OpenAIRE

    Sanders, JE; Harrison, DS; Allyn, KJ; Myers, TR

    2009-01-01

    Bioimpedance analysis was used to measure conductive tissue, extracellular fluid volume changes in the residual limbs of four unilateral trans-tibial amputee subjects during standing and walking conditions. Results were useful towards clinical assessment, patient education, and decision-making about treatment.

  16. Improving Program Results through the Use of Predictive Operational Performance Indicators: A Canadian Case Study

    Science.gov (United States)

    Barrados, Maria; Blain, J. S.

    2013-01-01

    In Canada, in-depth evaluations of federal programs are intended to occur every 5 years. As such, evaluation is a periodic retrospective (lag) indicator examining results achieved versus program objectives. In a Canadian context, stand-alone evaluations have proved challenging to implement, time consuming, and not well adapted to annual management…

  17. Investigating Personality in Stuttering: Results of a Case Control Study Using the NEO-FFI

    Science.gov (United States)

    Bleek, Benjamin; Montag, Christian; Faber, Jennifer; Reuter, Martin

    2011-01-01

    A recent study by Iverach et al. ("Journal of Communication Disorders," 2010) compared persons who stutter with two normative samples in the context of the five-factor model of personality measured by the NEO Five-Factor Inventory (NEO-FFI). Persons who stutter were characterized by higher "Neuroticism," lower "Conscientiousness" and lower…

  18. Colour anomia resulting from weakened short-term colour memory. A case study.

    Science.gov (United States)

    Davidoff, J B; Ostergaard, A L

    1984-06-01

    A patient exhibited marked colour anomia without object anomia, but was able to point to named colours. Five experiments were conducted to investigate his immediate colour memory. It was concluded that his colour anomia was the result of an impaired short-term memory deficit specific to colour. Temporary activation of specific entries in the colour lexicon enabled pointing and even naming to take place. A general model incorporating all forms of colour anomia is presented.

  19. Fetuin-A Characteristics during and after Pregnancy: Result from a Case Control Pilot Study

    Directory of Open Access Journals (Sweden)

    Serdar Farhan

    2012-01-01

    Results. Fasting fetuin-A correlated with BMI in women with former GDM (r=0.90, P<0.0001 but showed no association with parameters of glucose tolerance in women with GDM or post-GDM. GDM featured significantly lower insulin sensitivity and higher insulin and C-peptide secretion profiles compared to NGT during pregnancy (P<0.05. Fasting and postprandial fetuin-A did not differ between groups, neither during nor after pregnancy. Conclusion. Fetuin-A is not influenced by glucose tolerance during or after pregnancy or acute glucose elevations following glucose ingestion in young women, but closely relates to BMI early postpartum.

  20. [Study of the remote results of five cases of unilateral condylar hyperplasia in the adult].

    Science.gov (United States)

    Rey, P; Choitel, J; Souyris, F

    1984-01-01

    Exceptionally bilateral, condylar hyperplasia result in graduated facial asymmetry . The principal treatment is the condylectomy. (Condylar head and a portion of the neck of the condyle are removed.) Sometimes we must complete this condylectomy by mandibular osteotomy or resection of a segment of body of the mandible. The occlusal relationships of the teeth are affected by this process. That's why surgery treatment must be associated with orthodontics and prosthetic preparations. We use in post-operative immediate an intermaxillary fixation and traction by elastics. This allow to have a better congruence between the dental arches, and spare functional troubles. PMID:6587518

  1. Viral Hemorrhagic Fever Cases in the Country of Georgia: Acute Febrile Illness Surveillance Study Results

    OpenAIRE

    Kuchuloria, Tinatin; Imnadze, Paata; Chokheli, Maiko; Tsertsvadze, Tengiz; Endeladze, Marina; Mshvidobadze, Ketevan; Clark, Danielle V; Bautista, Christian T.; Fadeel, Moustafa Abdel; Pimentel, Guillermo; House, Brent; Hepburn, Matthew J.; Wölfel, Silke; Wölfel, Roman; Rivard, Robert G.

    2014-01-01

    Minimal information is available on the incidence of Crimean–Congo hemorrhagic fever (CCHF) virus and hantavirus infections in Georgia. From 2008 to 2011, 537 patients with fever ≥ 38°C for ≥ 48 hours without a diagnosis were enrolled into a sentinel surveillance study to investigate the incidence of nine pathogens, including CCHF virus and hantavirus. Of 14 patients with a hemorrhagic fever syndrome, 3 patients tested positive for CCHF virus immunoglobulin M (IgM) antibodies. Two of the pati...

  2. Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies

    DEFF Research Database (Denmark)

    Källberg, H; Jacobsen, Søren; Bengtsson, C;

    2009-01-01

    OBJECTIVES: To determine the association between risk of rheumatoid arthritis (RA) and alcohol consumption in combination with smoking and HLA-DRB1 shared epitope (SE). METHODS: Data from two independent case-control studies of RA, the Swedish EIRA (1204 cases and 871 controls) and the Danish...... CACORA (444 cases and 533 controls), were used to estimate ORs of developing RA for different amounts of alcohol consumed. RESULTS: Alcohol consumption was significantly more common in controls (p... alcohol consumers, the quarter with the highest consumption had a decreased risk of RA of the order of 40-50% compared with the half with the lowest consumption (EIRA, OR = 0.5 (95% CI 0.4 to 0.6); CACORA, OR = 0.6 (95% CI 0.4 to 0.9)). For the subset of RA that is seropositive for antibodies...

  3. Motivations, Risks, Barriers, and Results Associated with the Adoption of Global Sourcing by Brazilian Companies: a Case-Based Study

    OpenAIRE

    Moema Pereira Nunes

    2016-01-01

    This article aims to identi fy the motivations behind g lobal s ourcing (GS) adoption , the associated risks and barriers , and the results that companies from emerging countries are achieving . The research explores the distinguishing features of these companies ' experience and examines established theories about GS that are based on companies from developed countries. In the article, a case - based study investigat ed four companies from t...

  4. Non-hodgkin′s lymphoma and work in agriculture: Results of a two case-control studies in Saskatchewan, Canada

    Directory of Open Access Journals (Sweden)

    Chandima P Karunanayake

    2013-01-01

    Full Text Available Objectives: The objective was to examine the association between non-Hodgkin′s lymphoma (NHL and farming-related activities, gender, pesticides exposure, and exposure to chemicals other than pesticides in Saskatchewan. Materials and Methods: Male and female study participants were taken from two separate case-control studies conducted in Saskatchewan province, Canada. A case was defined as any man or woman aged 19 years and older with a first diagnosis of NHL registered by the Saskatchewan Cancer Agency during the study period. Conditional logistic regression was used to fit the statistical models. Results: Farming exposure and exposure to pesticides-contaminated cloths were related to an increased risk of NHL. Exposure to pesticides was strongly associated with an increased risk of NHL, especially for men. Conclusion: For men, the incidence of NHL was associated with exposure to pesticides after adjusting for other independent predictors.

  5. Assessing adherence in the CAPRISA 004 tenofovir gel HIV prevention trial: results of a nested case-control study.

    Science.gov (United States)

    MacQueen, Kathleen M; Weaver, Mark A; van Loggerenberg, Francois; Succop, Stacey; Majola, Nelisle; Taylor, Doug; Karim, Quarraisha Abdool; Karim, Salim Abdool

    2014-05-01

    Adherence undeniably impacts product effectiveness in microbicide trials, but the connection has proven challenging to quantify using routinely collected behavioral data. We explored this relationship using a nested case-control study in the CAPRISA 004 Tenofovir (TFV) gel HIV prevention trial. Detailed 3-month recall data on sex events, condom and gel use were collected from 72 incident cases and 205 uninfected controls. We then assessed how the relationship between self-reported adherence and HIV acquisition differed between the TFV and placebo gel groups, an interaction effect that should exist if effectiveness increases with adherence. The CAPRISA 004 trial determined that randomization to TFV gel was associated with a significant reduction in risk of HIV acquisition. In our nested case-control study, however, we did not observe a meaningful decrease in the relative odds of infection-TFV versus placebo-as self-reported adherence increased. To the contrary, exploratory sub-group analysis of the case-control data identified greater evidence for a protective effect of TFV gel among participants reporting less than 80 % adherence to the protocol-defined regimen (odds ratio (OR) 0.30; 95 % CI 0.11-0.78) than among those reporting ≥ 80 % adherence (Odds Ratio 0.81; 95 % CI 0.34-1.92). The small number of cases may have inhibited our ability to detect the hypothesized interaction between adherence and effectiveness. Nonetheless, our results re-emphasize the challenges faced by investigators when adherence may be miss-measured, miss-reported, or confounded with the risk of HIV. PMID:24647763

  6. Travel-related venous thrombosis: results from a large population-based case control study (MEGA study.

    Directory of Open Access Journals (Sweden)

    Suzanne C Cannegieter

    2006-08-01

    Full Text Available BACKGROUND: Recent studies have indicated an increased risk of venous thrombosis after air travel. Nevertheless, questions on the magnitude of risk, the underlying mechanism, and modifying factors remain unanswered. METHODS AND FINDINGS: We studied the effect of various modes and duration of travel on the risk of venous thrombosis in a large ongoing case-control study on risk factors for venous thrombosis in an unselected population (MEGA study. We also assessed the combined effect of travel and prothrombotic mutations, body mass index, height, and oral contraceptive use. Since March 1999, consecutive patients younger than 70 y with a first venous thrombosis have been invited to participate in the study, with their partners serving as matched control individuals. Information has been collected on acquired and genetic risk factors for venous thrombosis. Of 1,906 patients, 233 had traveled for more than 4 h in the 8 wk preceding the event. Traveling in general was found to increase the risk of venous thrombosis 2-fold (odds ratio [OR] 2.1; 95% confidence interval [CI] 1.5-3.0. The risk of flying was similar to the risks of traveling by car, bus, or train. The risk was highest in the first week after traveling. Travel by car, bus, or train led to a high relative risk of thrombosis in individuals with factor V Leiden (OR 8.1; 95% CI 2.7-24.7, in those who had a body mass index of more than 30 kg/m(2 (OR 9.9; 95% CI 3.6-27.6, in those who were more than 1.90 m tall (OR 4.7; 95% CI 1.4-15.4, and in those who used oral contraceptives (estimated OR > 20. For air travel these synergistic findings were more apparent, while people shorter than 1.60 m had an increased risk of thrombosis after air travel (OR 4.9; 95% CI 0.9-25.6 as well. CONCLUSIONS: The risk of venous thrombosis after travel is moderately increased for all modes of travel. Subgroups exist in which the risk is highly increased.

  7. Insights into the impact and use of research results in a residential long-term care facility: a case study

    Directory of Open Access Journals (Sweden)

    Cranley Lisa A

    2012-09-01

    Full Text Available Abstract Background Engaging end-users of research in the process of disseminating findings may increase the relevance of findings and their impact for users. We report findings from a case study that explored how involvement with the Translating Research in Elder Care (TREC study influenced management and staff at one of 36 TREC facilities. We conducted the study at ‘Restwood’ (pseudonym nursing home because the Director of Care engaged actively in the study and TREC data showed that this site differed on some areas from other nursing homes in the province. The aims of the case study were two-fold: to gain a better understanding of how frontline staff engage with the research process, and to gain a better understanding of how to share more detailed research results with management. Methods We developed an Expanded Feedback Report for use during this study. In it, we presented survey results that compared Restwood to the best performing site on all variables and participating sites in the province. Data were collected regarding the Expanded Feedback Report through interviews with management. Data from staff were collected through interviews and observation. We used content analysis to derive themes to describe key aspects related to the study aims. Results We observed the importance of understanding organizational routines and the impact of key events in the facility’s environment. We gleaned additional information that validated findings from prior feedback mechanisms within TREC. Another predominant theme was the sense that the opportunity to engage in a research process was reaffirming for staff (particularly healthcare aides—what they did and said mattered, and TREC provided a means of having one’s voice heard. We gained valuable insight from the Director of Care about how to structure and format more detailed findings to assist with interpretation and use of results. Conclusions Four themes emerged regarding staff engagement with

  8. Making Statistical Data More Easily Accessible on the Web Results of the StatSearch Case Study

    CERN Document Server

    Rajman, M; Boynton, I M; Fridlund, B; Fyhrlund, A; Sundgren, B; Lundquist, P; Thelander, H; Wänerskär, M

    2005-01-01

    In this paper we present the results of the StatSearch case study that aimed at providing an enhanced access to statistical data available on the Web. In the scope of this case study we developed a prototype of an information access tool combining a query-based search engine with semi-automated navigation techniques exploiting the hierarchical structuring of the available data. This tool enables a better control of the information retrieval, improving the quality and ease of the access to statistical information. The central part of the presented StatSearch tool consists in the design of an algorithm for automated navigation through a tree-like hierarchical document structure. The algorithm relies on the computation of query related relevance score distributions over the available database to identify the most relevant clusters in the data structure. These most relevant clusters are then proposed to the user for navigation, or, alternatively, are the support for the automated navigation process. Several appro...

  9. Barriers to implementation of a redesign of information transfer and feedback in acute care: results from a multiple case study

    OpenAIRE

    van Leijen-Zeelenberg, Janneke E; van Raak, Arno JA; Duimel-Peeters, Inge GP; Kroese, Mariëlle EAL; Brink, Peter RG; Ruwaard, Dirk; Vrijhoef, Hubertus JM

    2014-01-01

    Background Accurate information transfer is an important element of continuity of care and patient safety. Despite the demonstrated urge for improvement of communication in acute care, there is a lack of data on improvements of communication. This study aims to describe the barriers to implementation of a redesign of the existing model for information transfer and feedback. Methods A case study with six cases (i.e. acute care chains), using mixed methods was carried out in the Netherlands. Th...

  10. Non-hodgkin's lymphoma and work in agriculture: Results of a two case-control studies in Saskatchewan, Canada

    OpenAIRE

    Chandima P. Karunanayake; Dosman, James A; Punam Pahwa

    2013-01-01

    Objectives: The objective was to examine the association between non-Hodgkin′s lymphoma (NHL) and farming-related activities, gender, pesticides exposure, and exposure to chemicals other than pesticides in Saskatchewan. Materials and Methods: Male and female study participants were taken from two separate case-control studies conducted in Saskatchewan province, Canada. A case was defined as any man or woman aged 19 years and older with a first diagnosis of NHL registered by the Saskatchewan C...

  11. Managing Expectations: Results from Case Studies of US Water Utilities on Preparing for, Coping with, and Adapting to Extreme Events

    Science.gov (United States)

    Beller-Simms, N.; Metchis, K.

    2014-12-01

    Water utilities, reeling from increased impacts of successive extreme events such as floods, droughts, and derechos, are taking a more proactive role in preparing for future incursions. A recent study by Federal and water foundation investigators, reveals how six US water utilities and their regions prepared for, responded to, and coped with recent extreme weather and climate events and the lessons they are using to plan future adaptation and resilience activities. Two case studies will be highlighted. (1) Sonoma County, CA, has had alternating floods and severe droughts. In 2009, this area, home to competing water users, namely, agricultural crops, wineries, tourism, and fisheries faced a three-year drought, accompanied at the end by intense frosts. Competing uses of water threatened the grape harvest, endangered the fish industry and resulted in a series of regulations, and court cases. Five years later, new efforts by partners in the entire watershed have identified mutual opportunities for increased basin sustainability in the face of a changing climate. (2) Washington DC had a derecho in late June 2012, which curtailed water, communications, and power delivery during a record heat spell that impacted hundreds of thousands of residents and lasted over the height of the tourist-intensive July 4th holiday. Lessons from this event were applied three months later in anticipation of an approaching Superstorm Sandy. This study will help other communities in improving their resiliency in the face of future climate extremes. For example, this study revealed that (1) communities are planning with multiple types and occurrences of extreme events which are becoming more severe and frequent and are impacting communities that are expanding into more vulnerable areas and (2) decisions by one sector can not be made in a vacuum and require the scientific, sectoral and citizen communities to work towards sustainable solutions.

  12. Acoustic neuroma risk in relation to mobile telephone use: Results of the INTERPHONE international case-control study

    DEFF Research Database (Denmark)

    Berg-Beckhoff, Gabi

    2011-01-01

    Background: The rapid increase in mobile telephone use has generated concern about possible health risks of radiofrequency electromagnetic fields from these devices. Methods: A case-control study of 1105 patients with newly diagnosed acoustic neuroma (vestibular schwannoma) and 2145 controls...... exposure at five years before the reference date were also done to allow for a possible longer latent period. Results: The odds ratio (OR) of acoustic neuroma with ever having been a regular mobile phone user was 0.85 (95% confidence interval 0.69-1.04). The OR for ≥10 years after first regular mobile...... decile of cumulative hours of use. Conclusions: There was no increase in risk of acoustic neuroma with ever regular use of a mobile phone or for users who began regular use 10 years or more before the reference date. Elevated odds ratios observed at the highest level of cumulative call time could be due...

  13. Early pregnancy exposure to antihistamines and risk of congenital heart defects : results of two case-control studies

    NARCIS (Netherlands)

    Smedts, Huberdina P. M.; de Jonge, Linda; Bandola, Sarah J. G.; Baardman, Marlies E.; Bakker, Marian K.; Stricker, Bruno H. C.; Steegers-Theunissen, Regine P. M.

    2014-01-01

    UNLABELLED: We aimed to study the association between use of antihistamines in early pregnancy and congenital heart defects (CHD) in the offspring. DESIGN: Two case-control studies. SETTING: HAVEN study, Erasmus MC, University Medical Centre, Rotterdam, and Eurocat Northern Netherlands (NNL), Univer

  14. Travel-Related Venous Thrombosis: Results from a Large Population-Based Case Control Study (MEGA Study)

    NARCIS (Netherlands)

    Cannegieter, Suzanne C.; Doggen, Carine J.M.; Houwelingen, van Hans C.; Rosendaal, Frits R.

    2006-01-01

    Background Recent studies have indicated an increased risk of venous thrombosis after air travel. Nevertheless, questions on the magnitude of risk, the underlying mechanism, and modifying factors remain unanswered. Methods and Findings We studied the effect of various modes and duration of travel o

  15. Risk factors for MRSA infection in companion animals: results from a case-control study within Germany.

    Science.gov (United States)

    Vincze, Szilvia; Brandenburg, Anja G; Espelage, Werner; Stamm, Ivonne; Wieler, Lothar H; Kopp, Peter A; Lübke-Becker, Antina; Walther, Birgit

    2014-10-01

    Increasing numbers of companion animals suffering from infections with methicillin-resistant Staphylococcus aureus (MRSA) have been reported in the recent past. These infections are of particular concern because of the limited treatment options for MRSA and their transferability to humans. Since MRSA lineages isolated from infected companion animals often mirror typical human epidemic strains circulating in the same region, successful strategies to combat MRSA need strong and coordinated efforts from both, the human and the veterinary field according to the "One Health" concept. Hence, to identify potential risk factors related to MRSA infections in dogs, cats and horses, a case-control study was conducted, including data on 106 MRSA-infected animal patients as cases and 102 MSSA-infected animals as controls, originating from 155 different veterinary settings within Germany. Demographic data on animal patients, patient history and administration of antibiotics as well as practice/clinic specific parameters were assessed as putative risk factors. Multivariable logistic regression identified the following variables as risk factors for MRSA infection compared to MSSA infection: number of employees working at the veterinary setting (n>10; p<0.001), antibiotic treatment prior to sampling (systemic: p=0.002; local: p=0.049, both: p=0.011) and surgical site infection (p<0.001). Spa typing revealed predominantly clonal complexes well-known for hospital-associated lineages spreading in human health-care settings in Germany (CC5 and CC22) for isolates of dog and cat origin. CC398-MRSA dominated among equine isolates, a CC that was described as a nosocomial pathogen in equine clinical settings before. The identified risk factors and genotyping results are in accordance with numerous study outcomes from the field of human medicine and point towards reasonable problems with nosocomial spread of MRSA, especially within companion animal veterinary clinics. To define targeted

  16. Deaths resulting from the use of firearms by police against motor vehicles: Study of cases in Porto, Portugal.

    Science.gov (United States)

    Rodrigues, Ezequiel; Faria, Paula; Santos, Agostinho; Fraga, Sílvia

    2016-04-01

    The objective of this study was to investigate the terminal ballistics of police shootings in which the bullets went through any motor vehicle structure before fatally wounding the occupants. 6 cases that occurred in Porto district between 1998 and 2013 were studied. The firearms used were 7.65 mm (n = 1) or 9 mm (n = 3) calibre semi-automatic pistols and 9 mm calibre submachine guns (n = 2); the bullets were full metal jacket type. The metal jacket of the collected projectiles was totally or partially destroyed in 3 cases. It exhibited a deformed structure in all cases. The trajectories of the bullets in the vehicles were always more or less linear, even when initial impact was at an oblique angle. The entry holes in the victims' bodies were larger or much larger in size than the calibre of the bullets. They were located, with the exception of one of the cases, in the left half of the body. The trajectories in the victims' bodies were from front to back, in one case, and from back to front in all others. Exit wounds were only found in two cases. Death occurred immediately after the victim was shot only in one case, despite a vital structure has been hit in all cases. The cases studied support the idea that the use of firearms against vehicles with the sole intention of immobilisation entails uncontrollable danger to the lives of the occupants, and especially when done by police forces not specifically trained for that purpose. Therefore, such use of firearms should be avoided.

  17. Deaths resulting from the use of firearms by police against motor vehicles: Study of cases in Porto, Portugal.

    Science.gov (United States)

    Rodrigues, Ezequiel; Faria, Paula; Santos, Agostinho; Fraga, Sílvia

    2016-04-01

    The objective of this study was to investigate the terminal ballistics of police shootings in which the bullets went through any motor vehicle structure before fatally wounding the occupants. 6 cases that occurred in Porto district between 1998 and 2013 were studied. The firearms used were 7.65 mm (n = 1) or 9 mm (n = 3) calibre semi-automatic pistols and 9 mm calibre submachine guns (n = 2); the bullets were full metal jacket type. The metal jacket of the collected projectiles was totally or partially destroyed in 3 cases. It exhibited a deformed structure in all cases. The trajectories of the bullets in the vehicles were always more or less linear, even when initial impact was at an oblique angle. The entry holes in the victims' bodies were larger or much larger in size than the calibre of the bullets. They were located, with the exception of one of the cases, in the left half of the body. The trajectories in the victims' bodies were from front to back, in one case, and from back to front in all others. Exit wounds were only found in two cases. Death occurred immediately after the victim was shot only in one case, despite a vital structure has been hit in all cases. The cases studied support the idea that the use of firearms against vehicles with the sole intention of immobilisation entails uncontrollable danger to the lives of the occupants, and especially when done by police forces not specifically trained for that purpose. Therefore, such use of firearms should be avoided. PMID:26807993

  18. Lack of Association between Stroke and Left Atrial Out-Pouching Structures: Results of a Case-Control Study

    OpenAIRE

    Ko, Ji Young; Kim, Young Dae; Hong, Yoo Jin; Lee, Hye-Jeong; Hur, Jin; Choi, Byoung Wook; Heo, Ji Hoe; Kim, Young Jin

    2013-01-01

    Background and Purpose Clinical significance of out-pouching structures of the left atrium (LA) as potential embolic sources remains unclear. We sought to evaluate the association between stroke and LA out-pouching structures. Methods A case-control study was conducted to assess the prevalence of LA out-pouching structures in subjects with and without stroke. Case subjects were 270 stroke patients who had undergone cardiac CT. Control subjects were 270 age- and sex-matched patients without a ...

  19. Associations of serum organohalogen levels and prostate cancer risk: Results from a case-control study in Singapore.

    Science.gov (United States)

    Pi, Na; Chia, Sin Eng; Ong, Choon Nam; Kelly, Barry C

    2016-02-01

    There is increasing evidence that elevated exposure to organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) may lead to an increased risk of prostate cancer. As part of a hospital-based case-control study of the Singaporean male population, we investigated associations between organohalogen exposure and risk of prostate cancer. Trace residue concentrations of 74 organohalogen contaminants, including several PCBs, OCPs and halogenated flame retardants (HFRs), were determined in serum samples (n = 120) using gas chromatography tandem mass spectrometry (GC-MS/MS). A variety of OCPs, PCBs and HFRs were detected in samples of both patients and controls. Mean concentrations of p,p' DDT, p,p' DDE, PCB 118, PCB 138, PCB 153 and PCB 187 were significantly higher (p 67th) were 5.67 (95% CI, 2.37-13.54) and 2.14 (95% CI, 0.99 to 4.66), respectively. The results suggest that exposure to DDTs and PCBs may be associated with prostate cancer risk in Singaporean males. No such association was observed for the organohalogen flame retardants studied, including polybrominated diphenyl ethers (PBDEs). The study provides novel information regarding the occurrence, levels and potential associations with prostate cancer risk for several organohalogen contaminants in the Singapore population. However, further investigation and analyses should be conducted to confirm these findings.

  20. Insights into the impact and use of research results in a residential long-term care facility: a case study

    OpenAIRE

    Cranley Lisa A; Birdsell Judy M; Norton Peter G; Morgan Debra G; Estabrooks Carole A

    2012-01-01

    Abstract Background Engaging end-users of research in the process of disseminating findings may increase the relevance of findings and their impact for users. We report findings from a case study that explored how involvement with the Translating Research in Elder Care (TREC) study influenced management and staff at one of 36 TREC facilities. We conducted the study at ‘Restwood’ (pseudonym) nursing home because the Director of Care engaged actively in the study and TREC data showed that this ...

  1. Motivations, Risks, Barriers, and Results Associated with the Adoption of Global Sourcing by Brazilian Companies: a Case-Based Study

    Directory of Open Access Journals (Sweden)

    Moema Pereira Nunes

    2016-01-01

    Full Text Available This article aims to identi fy the motivations behind g lobal s ourcing (GS adoption , the associated risks and barriers , and the results that companies from emerging countries are achieving . The research explores the distinguishing features of these companies ' experience and examines established theories about GS that are based on companies from developed countries. In the article, a case - based study investigat ed four companies from the electrical and electronics industry in South Brazil. Data w ere collected through in - dep th interviews , documents , and direct observation. According to the research, t he main motivations for adopting GS are faster access to new technologies and establish ing a presence in global markets. It was also found that the opportunity to offer diversified products u sing the distribution channels already developed by companies motivate s GS adoption , a situation that prior literature has not identified . Despite the risks, t he absence of a broad local supply - base prompts companies to adopt GS. Further, the failure to fo rmalize barrier analysis processes creates difficulties f or companies . Th e main results associated with GS relate to innovation and reductions in the time taken to develop product s and reach market s . In this regard, c ompanies face a challenge to develop th e abilities required to compete for the advantages that t he global market can offer.

  2. Risk factors for breast cancer for women in Punjab, Pakistan:Results from a case-control study

    Directory of Open Access Journals (Sweden)

    Ghausia Masood Gilani

    2006-01-01

    Full Text Available Over the last three decades an increase in the incidence of breast cancer has been observed in the previously low-risk Asian countries. This study is designed to determine the risk factors of breast cancer for Pakistani women as little information exists in this regard. A case-control study of 564 female breast cancer cases diagnosed at the two cancer hospitals at Lahore (INMOL and SKMCH during the time period Jan 1, 1998 to Dec 31, 1998 was carried out. Four hundred and forty eight women aged 24-80 years out of 564 cases were complete with respect to defined criteria and were eligible for the study. Population-based controls were selected to match for age of cases in the ratio 1:2. The data were analyzed considering ‘all women’ and then separate analyses were done for ‘premenopausal’ and ‘postmenopausal women’. Women with family history of breast cancer, history of consanguineous marriage, smoking and high BMI (≥28 are at increased risk of breast cancer for all three groups. Early menarche (45 years was a strong determinant of breast cancer. Higher number of full-term pregnancies (>3 was protective for ‘all women’ and ‘premenopausal women’ but in case of ‘postmenopausal women’ the poor with higher number of pregnancies were significantly protected. Late age at first FTP (>25 years is a significant risk factor for postmenopausal women.

  3. A case study of nondelamination glass dissolution resulting in visible particles: implications for neutral pH formulations.

    Science.gov (United States)

    Ratnaswamy, Gayathri; Hair, Alison; Li, Gary; Thirumangalathu, Renuka; Nashed-Samuel, Yasser; Brych, Lejla; Dharmavaram, Vasumathi; Wen, Zai-Qing; Fujimori, Kiyoshi; Jing, Wendy; Sethuraman, Ananth; Swift, Rob; Ricci, Margaret Speed; Piedmonte, Deirdre Murphy

    2014-04-01

    Visible particles were unexpectedly observed in a neutral-pH placebo formulation stored in glass vials but were not observed in the same formulation composition that contained protein. The particles were identified as silica gel (SiO2 ) and polysorbate 20, suggesting dissolution of the glass vial. Time course studies were performed to assess the effect of variables such as pH, excipients, storage temperature, and duration on particle formation. Data suggest that glass dissolution occurred during the storage in the liquid state, as shown by increased Si levels in solution. Upon freezing, the samples underwent freeze concentration and likely became supersaturated, which resulted in the appearance of visible silica particles upon thawing. The glass degradation described here is unique and differs from the more commonly reported delamination, defined by the presence of reflective, shard-like glass flakes in solution that are often termed lamellae. This case study underscores the importance of an early assessment (during formulation development) of potential incompatibility of the formulation with the primary container.

  4. Epidemiology of Strongyloides stercoralis in northern Italy: results of a multicentre case-control study, February 2013 to July 2014.

    Science.gov (United States)

    Buonfrate, Dora; Baldissera, Mara; Abrescia, Fabrizio; Bassetti, Matteo; Caramaschi, Giacomo; Giobbia, Mario; Mascarello, Marta; Rodari, Paola; Scattolo, Novella; Napoletano, Giuseppina; Bisoffi, Zeno

    2016-08-01

    Strongyloides stercoralis is a soil-transmitted helminth widely diffused in tropical and subtropical regions of the world. Autochthonous cases have been also diagnosed sporadically in areas of temperate climate. We aimed at defining the epidemiology of strongyloidiasis in immigrants and Italians living in three northern Italian Regions. Screening for S. stercoralis infection was done with serology, confirmation tests were a second serological method or stool agar culture. A case-control approach was adopted and patients with a peripheral eosinophil count ≥ 500/mcL were classified as cases. Of 2,701 individuals enrolled here 1,351 were cases and 1,350 controls; 86% were Italians, 48% women. Italians testing positive were in 8% (97/1,137) cases and 1% (13/1,178) controls (adjusted odds ratio (aOR) 8.2; 95% confidence interval (CI): 4.5-14.8), while positive immigrants were in 17% (36/214) cases and in 2% (3/172) controls (aOR 9.6; 95% CI: 2.9-32.4). Factors associated with a higher risk of infection for all study participants were eosinophilia (p < 0.001) and immigration (p = 0.001). Overall, strongyloidiasis was nine-times more frequent in individuals with eosinophilia than in those with normal eosinophil count. PMID:27525375

  5. Results of case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria.

    OpenAIRE

    Gardner, M. J.; Snee, M P; Hall, A J; Powell, C A; Downes, S; Terrell, J D

    1990-01-01

    OBJECTIVE--To examine whether the observed excess of childhood leukaemia and lymphoma near the Sellafield nuclear plant is associated with established risk factors or with factors related to the plant. DESIGN--A case-control study. SETTING--West Cumbria health district. SUBJECTS--52 Cases of leukaemia, 22 of non-Hodgkin's lymphoma, and 23 of Hodgkin's disease occurring in people born in the area and diagnosed there in 1950-85 under the age of 25 and 1001 controls matched for sex and date of b...

  6. Occupation and risk of glioma, meningioma and acoustic neuroma: results from a German case-control study (interphone study group, Germany)

    DEFF Research Database (Denmark)

    Samkange-Zeeb, F; Schlehofer, B; Schüz, J;

    2010-01-01

    /electronic and transport, and the risk of glioma, meningioma and acoustic neuroma. METHODS: In a population-based case-control study involving a total of 844 cases and 1688 controls conducted from 2000 to 2003, detailed information on life-long job histories was collected during personal interviews and used to create job......: Most of the observed odds ratios were close to 1.0 for ever having worked in the six occupational sectors and risk of glioma, meningioma and acoustic neuroma. Sub-group analyses according to duration of employment resulted in two elevated odds ratios with confidence intervals excluding unity...

  7. Lifestyle factors and lumbar disc disease : results of a German multi-center case-control study (EPILIFT).

    OpenAIRE

    Schumann, Barbara; Bolm-Audorff, Ulrich; Bergmann, Annekatrin; Ellegast, Rolf; Elsner, Gine; Grifka, Joachim; Haerting, Johannes; Jäger, Matthias; Michaelis, Martina; Seidler, Andreas

    2010-01-01

    INTRODUCTION: In the large-scale case-control study EPILIFT, we investigated the dose-response relationship between lifestyle factors (weight, smoking amount, cumulative duration of different sports activities) and lumbar disc disease. METHODS: In four German study regions (Frankfurt am Main, Freiburg, Halle/Saale, Regensburg), 564 male and female patients with lumbar disc herniation and 351 patients with lumbar disc narrowing (chondrosis) aged 25 to 70 years were prospectively recruited. Fro...

  8. Results From a Hypothesis Generating Case-Control Study: Herpes Family Viruses and Schizophrenia Among Military Personnel

    OpenAIRE

    David W Niebuhr; Millikan, Amy M.; Yolken, Robert; Li, Yuanzhang; Weber, Natalya S.

    2007-01-01

    Background: Herpes family viruses can cause central nervous system inflammatory changes that can present with symptoms indistinguishable from schizophrenia and therefore are of interest in schizophrenia research. Most existing studies of herpes viruses have used small populations and postdiagnosis specimens. As part of a larger research program, we conducted a hypothesis-generating case-control study of selected herpes virus antibodies among individuals discharged from the US military with sc...

  9. Antioxidant defense markers modulated by glutathione S-transferase genetic polymorphism: results of lung cancer case-control study.

    Science.gov (United States)

    Reszka, Edyta; Wasowicz, Wojciech; Gromadzinska, Jolanta

    2007-12-01

    Oxidative stress and xenobiotic metabolizing enzymes are suspected to be related to carcinogenesis by different cellular mechanisms. Hence, our study aimed at identifying potential relationships between antioxidant defense parameters measured in blood and glutathione S-transferase (GST) genetic polymorphisms of four GST izoenzymes in lung cancer patients and reference individuals. The case-control study included 404 lung cancer patients and 410 non-cancer subjects as controls, matched by age, gender and place of living (central Poland). In control subjects with GSTM3*A/*A, GSTT1 null, GSTM1 null + GSTT1 null, GSTM3*A/*A + GSTT1 null genotype, glutathione peroxidase activity was significantly higher (P < 0.05) than in controls possessing respective potential protective GST genotypes. Controls with GSTM3*A/*A + GSTP1*B genotype presented significantly higher ceruloplasmin activity (P < 0.05) than GSTM3*B + GSTP1*A/*A carriers. Zinc level was significantly higher (P < 0.05) in controls and cases with GSTP1*B + GSTT1 null genotype and in cases with GSTM1 null + GSTP1*B genotype, when compared with respective potential protective GST genotypes. This case-control study indicates that particular defective GST genotypes may enhance the defense against oxidative stress. The potential relationship between the investigated antioxidative enzymes and microelements, and common functional genetic polymorphism of GST was observed mostly in control subjects. PMID:18850183

  10. A Case Study Correlating Innovative Gamma Ray Scanning Detection Systems Data to Surface Soil Gamma Spectrometry Results - 13580

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Shannon; Rodriguez, Rene; Billock, Paul [HydroGeoLogic, Inc., 11107 Sunset Hills Road, Suite 400, Reston, VA 20190 (United States); Lit, Peter [Nomad Science Group, 7738 Nautilus Shell Street, Las Vegas, NV 89139 (United States)

    2013-07-01

    HydroGeoLogic (HGL), Inc. completed a United States Environmental Protection Agency (USEPA) study to characterize radiological contamination at a site near Canoga Park, California. The characterized area contained 470 acres including the site of a prototype commercial nuclear reactor and other nuclear design, testing, and support operations from the 1950's until 1988 [1]. The site history included radiological releases during operation followed by D and D activities. The characterization was conducted under an accelerated schedule and the results will support the project remediation. The project has a rigorous cleanup to background agenda and does not allow for comparison to risk-based guidelines. To target soil sample locations, multiple lines of evidence were evaluated including a gamma radiation survey, geophysical surveys, historical site assessment, aerial photographs, and former worker interviews. Due to the time since production and decay, the primary gamma emitting radionuclide remaining is cesium-137 (Cs-137). The gamma ray survey covered diverse, rugged terrain using custom designed sodium iodide thallium-activated (NaI(Tl)) scintillation detection systems. The survey goals included attaining 100% ground surface coverage and detecting gamma radiation as sensitively as possible. The effectiveness of innovative gamma ray detection systems was tested by correlating field Cs-137 static count ratios to Cs-137 laboratory gamma spectrometry results. As a case study, the area encompassing the former location of the first nuclear power station in the U. S. was scanned, and second by second global positioning system (GPS)-linked gamma spectral data were evaluated by examining total count rate and nuclide-specific regions of interest. To compensate for Compton scattering from higher energy naturally occurring radionuclides (U-238, Th-232 and their progeny, and K-40), count rate ratios of anthropogenic nuclide-specific regions of interest to the total count rate

  11. - A case study for sessile oak (Quercus petraea) distribution - Preliminarly results of a Decision Support System for climate impact analysis

    Science.gov (United States)

    Gulyás, Krisztina; Gálos, Borbála; Berki, Imre; Czimber, Kornél

    2014-05-01

    Rainfed sectors of forestry are threatened by projected climate change especially in low-elevation regions in Southeast Europe, where precipitation is the limiting factor of production and ecosystem stability. To initiate preparation for frequency increase of extreme events, disasters and economic losses, a Decision Support System is under development, which provides GIS-supported information about the most important regional and local risks and mitigation options regarding climate change impacts. The case study will focus on the following aspects: • For the time period 1961-2010, precipitation and temperature means and extreme events have been analyzed in the Carpathian basin, using gridded station data from the EU-project CARPATCLIM (http://www.carpatclim-eu.org). • The climate indicators have been identified that characterize and determine the distribution, healty status and vitality of sessile oak. • As a product of the Decision Support System a distribution model is under development, which describes the connection between climate conditions and the distribution of sessile oak. The case study shows, how climate data can be used for impact analyses in the forestry sector. Applying different climate change scenarios, the expected distribution of tree species can be simulated. Acknowledgements: The development of the Decision Support System "Agrárklíma" is supported by TÁMOP-4.2.2.A-11/1/KONV and 4.2.2.B-10/1-2010-0018 "Talentum" joint EU-national research projects. Keywords: climate change, decision support system, distribution model, sessile oak

  12. Dietary factors and the risk of glioma in adults: results of a case-control study in Melbourne, Australia.

    Science.gov (United States)

    Giles, G G; McNeil, J J; Donnan, G; Webley, C; Staples, M P; Ireland, P D; Hurley, S F; Salzberg, M

    1994-11-01

    In a population-based case-control study of 416 incident gliomas in adults carried out in Melbourne, Australia, between 1987 and 1991, 409 age-sex-matched case-control pairs (243 male and 166 female) had adequate data available to examine associations between the dietary intake of N-nitroso compounds, N-nitroso precursors, other nutrients including N-nitroso inhibitors, and the risk of glioma. Dietary intakes were based on the reported frequency of consumption of 59 food items. Increased odds ratio (OR) were observed in males who consumed high levels of bacon, corned meats, apples, melons and oil. OR less than unity were observed in men consuming cabbage and cola drinks, and in women who consumed wholegrain bread, pasta, corned meat, bananas, cauliflower, brocoli, cola drinks and nuts. Generally, N-nitroso associations were greater in men and micronutrient associations were greater in women. Elevated OR in men, but not women, were associated with the intake of N-nitroso dimethylamine (NDMA), retinol and vitamin E. The intake of nitrate (largely of vegetable origin) was protective in women but not in men. When analyzed using multiple logistic regression, the association with NDMA intake in males was not modified by dietary micronutrient intakes. In females, beta carotene alone, though not directly associated with risk, modified the effect of NDMA. On balance, this study added only limited support to the N-nitroso hypothesis of glial carcinogenesis. PMID:7927941

  13. ANALYSIS OF THE RECONCILIATION OF THE ACCOUNTING RESULT WITH THE FISCAL RESULT. CASE STUDY: THE COMPANY “MACOM UNIREA” SRL HUNEDOARA

    OpenAIRE

    ILIE RĂSCOLEAN; ILEANA-SORINA RAKOS; TRAIAN-OVIDIU CALOTĂ

    2015-01-01

    By the present paper, the authors aim to analyze the reconciliation between the accounting result and the fiscal result obtained by a company of the Romanian national economy. Based on an empirical study, this analysis aims to determine the taxable profit for the period 01.01.2013-31.12.2015, during which we determined the tax refunds and non-refundable expenses through the prism of the influence of taxation – as a lever stimulating the activity of the company, but also constraini...

  14. Childhood cancer and residential radon exposure - results of a population-based case-control study in Lower Saxony (Germany)

    Energy Technology Data Exchange (ETDEWEB)

    Kaletsch, U.; Kaatsch, P.; Meinert, R.; Schuez, J.; Michaelis, J. [Institut fuer Medizinische Statistik und Dokumentation, Johannes-Gutenberg-Universitaet, D-55101 Mainz (Germany); Czarwinski, R. [Bundesamt fuer Strahlenschutz, Fachbereich ST, D-10318 Berlin (Germany)

    1999-09-01

    A population-based case-control study on risk factors for childhood malignancies was used to investigate a previously reported association between elevated indoor radon concentrations and childhood cancer, with special regard to leukaemia. The patients were all children suffering from leukaemia and common solid tumours (nephroblastoma, neuroblastoma, rhabdomyosarcoma, central nervous system (CNS) tumours) diagnosed between July 1988 and June 1993 in Lower Saxony (Germany) and aged less than 15 years. Two population-based control groups were matched by age and gender to the leukaemia patients. Long-term (1 year) radon measurements were performed in those homes where the children had been living for at least 1 year, with particular attention being paid to those rooms where they had stayed most of the time. Due to the sequential study design, radon measurements in these rooms could only be done for 36% (82 leukaemias, 82 solid tumours and 209 controls) of the 1038 families initially contacted. Overall mean indoor radon concentrations (27 Bq m{sup -3}) were low compared with the measured levels in other studies. Using a prespecified cutpoint of 70 Bq m{sup -3}, no association with indoor radon concentrations was seen for the leukaemias (odds ratio (OR): 1.30; 95% confidence interval (95% CI): 0.32-5.33); however, the risk estimates were elevated for the solid tumours (OR: 2.61; 95% CI: 0.96-7.13), mainly based on 6 CNS tumours. We did not find any evidence for an association between indoor radon and childhood leukaemia, which is in line with a recently published American case-control study. There is little support for an association with CNS tumours in the literature. (orig.)

  15. “Remotion” Total Wrist Arthroplasty: Preliminary Results of a Prospective International Multicenter Study of 215 Cases

    DEFF Research Database (Denmark)

    Herzberg, Guillaume; Boeckstyns, Michel Ernest Henri; Sorensen, Allan Ibsen;

    2012-01-01

    This study reports the current results of an international multicenter study of one last generation total wrist arthroplasty (TWA) ("ReMotion," Small Bone Innovation, Morristown, PA). The two first authors (G.H. and M.B.) built a Web-based prospective database including clinical and radiological ...

  16. Pulmonary Embolism in Pneumonia: Still a Diagnostic Challenge? Results of a Case-Control Study in 100 Patients

    Directory of Open Access Journals (Sweden)

    Maria Paparoupa

    2016-01-01

    Full Text Available This study evaluated the diagnostic value of D-dimer, CRP, and leucocytes count to detect an underlying pulmonary embolism (PE in patients with pneumonia. A predictive model of an underlying PE, based on laboratory markers and clinical symptoms, was our ultimate objective. Overall 100 patients underwent a computed tomography angiography (CTA of the lung: 54 with coexistence of PE and pneumonia (cases and 46 with pneumonia without PE (controls. Cases and controls were matched 1 : 1. Symptoms and paraclinical findings were registered on admission. Receiver operating characteristic (ROC curves, search for an optimal threshold, and conditional logistic regression analysis were conducted. D-dimer has a moderate ability to detect PE in pneumonia. Sensitivity of D-dimer was estimated at 97.78% and specificity at 11.11%. No optimal cut-point has acceptable diagnostic ability. After excluding patients with sepsis, sensitivity was reduced to 96.97%, whereas specificity increased to 16.13%. Consolidation in chest X-ray and positive D-dimer predict better an underlying PE as D-dimer itself. Thus, discriminatory power of the prediction model (AUC of 0.740 is not much greater than D-dimer (AUC of 0.703. No threshold that could increase the diagnostic value of D-dimer or a prediction model which is significantly better than D-dimer itself was identified.

  17. Reduced Risk of Human Lung Cancer by Selective Cyclooxygenase 2 (Cox-2 Blockade: Results of a Case Control Study

    Directory of Open Access Journals (Sweden)

    Randall E. Harris, Joanne Beebe-Donk, Galal A. Alshafie

    2007-01-01

    Full Text Available We conducted a case control study of selective cyclooxygenase-2 (COX-2 blocking agents and lung cancer. A total of 492 newly diagnosed lung cancer cases were ascertained during January 1, 2002 to September 30, 2004, at The Ohio State University Medical Center, Columbus, Ohio. All cases were confirmed by examination of the pathology report. Healthy population controls without cancer were ascertained during the same time period. Controls were frequency matched at a rate of 2:1 to the cases by age, gender, and county of residence. We collected information on type, frequency, and duration of use of selective COX-2 inhibitors (primarily celecoxib or rofecoxib and nonselective NSAIDs such as ibuprofen and aspirin. Estimates of odds ratios (OR were obtained with adjustment for cigarette smoking, age and other potential confounders using logistic regression analysis. Odds Ratios for selective COX-2 inhibitors were adjusted for past use of other NSAIDs. Use of any selective COX-2 inhibitor for more than one year produced a significant (60% reduction in the risk of lung cancer (OR=0.40, 95% CI=0.19-0.81. Observed risk reductions were consistent for men (OR=0.26, 95% CI=0.10-0.62 and women (OR=0.52, 95% CI=0.24-1.13 and for individual COX-2 inhibitors (OR=0.28, 95% CI=-0.12-0.67, for celecoxib and OR=0.55, 95% CI=0.19-1.56, for rofecoxib. Intake of ibuprofen or aspirin also produced significant risk reductions (OR=0.40, 95% CI=0.23-0.73 and OR=0.53, 95% CI=0.34-0.82, respectively, whereas acetaminophen, an analgesic with negligible COX-2 activity, had no effect on the risk (OR=1.36, 95% CI=0.53-3.37. This investigation demonstrates for the first time that selective COX-2 blocking agents have strong potential for the chemoprevention of human lung cancer.

  18. Work-related psychosocial events as triggers of sick leave - results from a Swedish case-crossover study

    Directory of Open Access Journals (Sweden)

    Lindholm Christina

    2011-03-01

    Full Text Available Abstract Background Although illness is an important cause of sick leave, it has also been suggested that non-medical risk factors may influence this association. If such factors impact on the period of decision making, they should be considered as triggers. Yet, there is no empirical support available. The aim was to investigate whether recent exposure to work-related psychosocial events can trigger the decision to report sick when ill. Methods A case-crossover design was applied to 546 sick-leave spells, extracted from a Swedish cohort of 1 430 employees with a 3-12 month follow-up of new sick-leave spells. Exposure in a case period corresponding to an induction period of one or two days was compared with exposure during control periods sampled from workdays during a two-week period prior to sick leave for the same individual. This was done according to the matched-pair interval and the usual frequency approaches. Results are presented as odds ratios (OR with 95% confidence intervals (CI. Results Most sick-leave spells happened in relation to acute, minor illnesses that substantially reduced work ability. The risk of taking sick leave was increased when individuals had recently been exposed to problems in their relationship with a superior (OR 3.63; CI 1.44-9.14 or colleagues (OR 4.68; CI 1.43-15.29. Individuals were also more inclined to report sick on days when they expected a very stressful work situation than on a day when they were not under such stress (OR 2.27; CI 1.40-3.70. Conclusions Exposure to problems in workplace relationships or a stressful work situation seems to be able to trigger reporting sick. Psychosocial work-environmental factors appear to have a short-term effect on individuals when deciding to report sick.

  19. Results of case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria

    International Nuclear Information System (INIS)

    In 1983 a television program alleged an increased incidence of leukemia in young persons living close to the largest nuclear plant in Britain: Sellafield. In response to widespread public concern, the government convened a committee of experts to examine the allegation. This group confirmed a ten fold increase in leukemia in young persons resident in the vicinity of the plant, but could not provide an explanation for the observation. A case control study mounted by the Medical Research Council's Environmental Epidemiology Unit has shown that the raised risk of developing leukemia in children born near Sellafield was explained, at least statistically, by the preconception exposure of their fathers' to ionizing radiation. This association has not been reported before in human subjects, and much research is underway to investigate this and other possible transgenerational effects of radiation

  20. Dental students' perceived preparedness to treat patients in clinic after a fixed prosthodontics course: survey results of a case study.

    Science.gov (United States)

    Barrero, Carlos; Duqum, Ibrahim; Petrola, Frank

    2015-04-01

    Previous research regarding dental students has found modest predictive value in preclinical didactic course grades in predicting clinical performance, but systematic assessment of students' feedback on their perceived preparedness has received little attention as a preclinical assessment methodology. The aim of this study was to assess the perceptions of the dental students at one U.S. academic dental institution regarding their preparedness for clinical performance following the preclinical fixed prosthodontics course. Third- and fourth-year dental students participated in a survey about their perceived preparedness to diagnose and treat patients with fixed prosthodontics needs in the school's dental clinics. The respondents (79 out of 161 students, for a response rate of 49%) rated each item on a five-point Likert scale. Responses about which preclinical procedures of the course prepared students the least and the best were consistent for the third- and fourth-year students. Less than 60% of all responding students felt prepared for planning complex cases and performing laboratory-related procedures. The findings of this study indicate that improvement is required in teaching students about laboratory procedures and problem-solving to adequately prepare them for clinical treatment of patients with fixed prosthodontics needs. PMID:25838012

  1. Etiology of newly-diagnosed cases of chronic liver disease in Southern Italy: results of a prospective multicentric study

    Directory of Open Access Journals (Sweden)

    Antonio Ascione

    2013-11-01

    Full Text Available The pattern of liver diseases has radically changed in our country over the last few decades. We prospectively collected data on the newly-diagnosed cases of chronic liver diseases in a region of southern Italy after about a decade from the last epidemiological study. We conducted a multicentric prospective study that enrolled 631 patients from 21 Liver Centers of the Campania region (Southern Italy at their first hospital admission or at their first outpatient visit. In our cohort of 631 patients (367 males, 263 females, 397 (62.9% were hepatitis C virus (HCV positive, 75 (11.9% were hepatitis B virus (HBV positive, 8 (1.3% were co-infected by HBV and HCV, 73 (11.6% had an alcoholic liver disease and 64 (10.1% had a nonalcoholic fatty liver disease. HBV infection was present in young people with a higher-than-expected prevalence, despite the vaccination program which should have involved this population. HCV chronic hepatitis still remains the most common cause of liver disease in our region. HBV infection still continues to represent a health problem in young people, despite the vaccination program.

  2. Driving student-centred calculus: results of a comprehensive case study for Kaizen learning in the Sultanate of Oman

    Science.gov (United States)

    Heim, Bernhard; Rupp, Florian; Viet, Nils; Stockhausen, Paul v.; Gallenkämper, Jonas; Kreuzer, Judith

    2015-04-01

    The art of teaching freshmen students is undergoing a rapid paradigm change. Classical forms of teaching are not applicable any more and an unmanageable offer of new multimedia tools and concepts is glutting the market. Moreover, compared to previous courses, the class size triples. In view of these challenges, we implemented a new teaching concept best described as Kaizen learning. By Kaizen learning, we define a teaching philosophy that is based on a concise mix of short learning units (with feedback loops and tests) and of carefully chosen repetitions (also with feedback loops and tests) to calibrate a course for the students. Here, this intensive blended, student-centred learning paradigm is analysed together with its direct impact on the students' performance. This case study leads to easy-to-implement key drivers for successfully teaching science in Oman, such as (1) human-human interaction, (2) clearly communicated expectations, (3) avoidance of a short-term learning attitude, (4) a no-calculator policy, (5) continuous Kaizen learning, and (6) balanced combination of traditional teaching and e-learning.

  3. [The role of ecological studies to evaluate the impact of an enviromental factor on health: a case study on the results of the SENTIERI project].

    Science.gov (United States)

    Donato, Francesco; Raffetti, Elena

    2014-01-01

    A case-study regarding the results of the SENTIERI project on the Brescia-Caffaro NPCS (National Priority Contaminated Site) is reported. This area has been polluted mainly by polychlorinated biphenyls (PCBs), which have been classified recently by the International Agency for Research on Cancer as human carcinogens (group 1), with sufficient evidence for melanoma and limited for non-Hodgkin lymphoma (NHL) and breast cancer. The 3rd report of the SENTIERI project (2014) has shown an excess of cancer incidence with respect to the expected, on the basis of the incidence rates from the pool of Centre-North Italy cancer registries, but a mortality similar to that expected according to the regional rates, for melanoma, NHL and breast cancer. Furthermore, a higher than expected incidence has been found for various cancers which are not associated a priori with PCB exposure. The Brescia Local Health Authority has also carried out an analysis of cancer incidence, which has shown an incidence in the area similar to other ones in North Italy and a cluster of cases centered on Brescia town for melanoma only. A possible explanation of these discrepancies is the use of different reference populations for the comparisons (Region and pool of Centre-North Italy cancer registries), besides possible confounding bias. We discuss here the most critical aspects of modern ecological studies, their potential information content and interpretation limits. PMID:25759337

  4. Case Study: Writing a Journal Case Study

    Science.gov (United States)

    Prud'homme-Genereux, Annie

    2016-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue describes incorporating a journal article into the classroom by first converting it into a case study.

  5. Do case-only designs yield consistent results between them and across different databases (DB)? Hip fractures associated with Benzodiazepines (BZD) as a case study

    NARCIS (Netherlands)

    Requena, Gema; Logie, John; Martin, Elisa; Huerta, Consuelo; González-González, Rocio; Boudiaf, Nada; Álvarez, Arturo; Bate, Andrew; García-Rodríguez, Luis A.; Reynolds, Robert; Schlienger, Raymond G.; De Groot, Mark C.H.; Klungel, Olaf H.; De Abajo, Francisco J.; Douglas, Ian

    2014-01-01

    Background: The case crossover (CXO) and selfcontrolled case series designs (SCCS) are increasingly used in pharmacoepidemiology. In both designs relative risk estimates are obtained within persons rather than between persons thus implicitly controlling for fixed confounding variables. Objectives: T

  6. Levels of prolactin in relation to coagulation factors and risk of venous thrombosis. Results of a large population-based case-control study (MEGA-study)

    NARCIS (Netherlands)

    Stuijver, D.J.; Debeij, J.; Zaane, B. van; Dekkers, O.M.; Smit, J.W.A.; Buller, H.R.; Rosendaal, F.R.; Gerdes, V.E.; Cannegieter, S.C.

    2012-01-01

    The pituitary hormone prolactin is thought to influence coagulation. We aimed to study the relation between prolactin levels, coagulation factors and risk of venous thrombosis (VT). We used data from a large population based case-control study into aetiology of first VT (MEGA-study). Prolactin level

  7. Usefulness of phytoremediation in sites with high levels of potentially toxic elements: results for a case study

    Science.gov (United States)

    Pérez-Sirvent, Carmen; Hernandez Perez, Carmen; Martínez Sanchez, Maria Jose; García Lorenzo, Mariluz; Hernandez-Cordoba, Manuel; Bech, Jaume

    2016-04-01

    An artificial pond was constructed with two topsoils collected from Portman Bay (SE Spain). This area is heavily polluted as a result of historical mining and processing activities, during which time great amounts of wastes were produced, characterised by a high PTE content, acidic pH and minerals resulting from supergene alteration. In order to simulate the mixing with carbonate materials, which naturally occurs in the study area, a stabilisation approach was applied by mixing with 30 % of limestone filler. Three replicate experiments involving aquatic macrophytes Phragmites australis, Juncus effusus and Iris pseudacorus were carried out, each type of sediment being prepared in pots for the three selected species. The total PTEs content (As, Cd, Cu, Fe, Pb and Zn) was determined and the bioconcentration factor (BCF) and transfer factor (TF) calculated. Under the reducing conditions existing in the wetland, the PTEs could be absorbed by the roots, particularly iron. Within the root, the conditions become more oxidising and insoluble compounds, such as iron oxyhydroxides, are formed, avoiding that PTEs be transferred to leaves. This behaviour was observed for the three selected species. The rest of the PTEs were also retained in the plant root. The results indicate that it is feasible to use the selected species for phytoremediation of soil contaminated with PTEs. Both Juncus effuses and Phragmites australis, as well as Iris pseudacorus could be considered as bioindicators, and natural or artificial wetlands containing these species could be usedful for remediation purposes.

  8. Normalization of Phenotypic Data from a Clinical Data Warehouse: Case Study of Heterogeneous Blood Type Data with Surprising Results.

    Science.gov (United States)

    Cimino, James J

    2015-01-01

    Clinical data warehouses often contain analogous data from disparate sources, resulting in heterogeneous formats and semantics. We have developed an approach that attempts to represent such phenotypic data in its most atomic form to facilitate aggregation. We illustrate this approach with human blood antigen typing (ABO-Rh) data drawn from the National Institutes of Health's Biomedical Translational Research Information System (BTRIS). In applying the method to actual patient data, we discovered a 2% incidence of changed blood types. We believe our approach can be applied to any institution's data to obtain comparable patient phenotypes. The actual discrepant blood type data will form the basis for a future study of the reasons for blood typing variation.

  9. Effects of elevated vacuum on in-socket residual limb fluid volume: Case study results using bioimpedance analysis

    Directory of Open Access Journals (Sweden)

    Joan E. Sanders, PhD

    2011-12-01

    Full Text Available Bioimpedance analysis was used to measure the residual limb fluid volume of seven transtibial amputee subjects using elevated vacuum sockets and nonelevated vacuum sockets. Fluid volume changes were assessed during sessions with the subjects sitting, standing, and walking. In general, fluid volume losses during 3 or 5 min walks and losses over the course of the 30 min test session were less for elevated vacuum than for suction. Numerous variables, including the time of day that data were collected, soft tissue consistency, socket-to-limb size and shape differences, and subject health, may have affected the results and had an equivalent or greater effect on limb fluid volume compared with elevated vacuum. Researchers should well consider these variables in the study design of future investigations on the effects of elevated vacuum on residual limb volume.

  10. Health risks resulting from contaminants transfers in soil-plants systems: case study of Atrazine in Lactuca sativa.

    Science.gov (United States)

    Mathieu, Camoin

    2015-04-01

    Food safety is presently at the center of great part of scientific and political debates. This represents a field of study in its own right of health risks, including ingestion by humans of hazardous biological, physical, chemical or radiological substances, from contaminated foods during different stages of production. Plant cultivation step is often one of the main sources of contamination, whether of voluntary (pesticide application) or accidental (nuclear, industrial waste, etc.) origin. As a result, the plants growth in an contaminated environment may increase the risk of transfer within the plant, and finally the exposure of humans. Furthermore, pesticides are among the main contaminants investigated in the frame of human health risks resulting from food intakes. However, most of these scientific works focus mainly on their occurrence and persistence in water bodies, and few of them are interested in soil/plants transfer. In this context, the understanding of the processes governing transfers of pesticides in plants is become a necessity, in particular to prevent human risks linked the ingestion of food produced in contaminated environments. This objective can be reached by studying the pollutants behavior in soils/plants transfers, and using various substances/plants couples. In our study, we selected a salad/pesticide couple as our experimental model. Atrazine was chosen as model contaminant because of its problematic presence in a large amount of environmental compartments, its physico-chemical properties and because of its long-term toxicity. Lactuca sativa has been selected as model plant because of its importance in French agriculture, and specifically in Languedoc-Roussillon. Salad has been cultivated in peats and irrigated with an atrazine spiked water solution (concentrations from 10 to 100 μg/L). Plant growth in such conditions has been compared to a growth in clean condition (irrigation with non spiked water). Measurements of atrazine contents in

  11. Effects of earthquakes on the deep repository for spent fuel in Sweden based on case studies and preliminary model results

    International Nuclear Information System (INIS)

    The Baltic Shield is one of the most stable areas in the world. Earthquakes have only on a few occasions exceeded magnitude 4 in Sweden in modern times. The safety case for a deep repository for spent fuel however includes an earthquake scenario due to the following reason: Earthquakes with much greater magnitudes occurred in northern Sweden during the most recent deglaciation period some 9,000 - 10,000 years ago when re-activated faults ruptured the surface. One of the most prominent evidences is the Paervie fault in Lapland, Sweden. The displacements exceeded 10 m in places and occurred over distances of around 150 km. The deep repository is designed to keep radiation well below the natural, ambient radiation for any time in the future. The safety function is achieved by a combination of engineered and natural barriers. One important safety issue is that future displacements in the rock should be less than 0.1 m at the precise location where the engineered canisters containing the waste are emplaced in the rock. Larger displacements could damage the canister that is designed to be tight for several 100,000 of years. SKB now re-visits the issues of seismic effects on underground facilities to supplement and update previous work. The project Effects of Earthquakes on Underground Facilities aims to re-compile field evidences of seismic damage on underground facilities, to shed additional light on the matter of friction loss in bedrock due to water-level changes and finally to find suitable ways to inform concerned citizens on the matter. The fact-finding was carried out in the form of interviews, literature surveys, Internet searches and by sending letters to some 60 organisations and researchers asking for co-operation. The most important conclusions are: Earthquake impact during the pre-closure phase: Damage due to shaking in an underground facility may occur if the peak ground acceleration exceeds 2 m/s2. Sweden is located in the Baltic Shield that is seismically

  12. Evaluating the improvements of the BOLAM meteorological model operational at ISPRA: A case study approach - preliminary results

    Science.gov (United States)

    Mariani, S.; Casaioli, M.; Lastoria, B.; Accadia, C.; Flavoni, S.

    2009-04-01

    Fritsch. A fully updated serial version of the BOLAM code has been recently acquired. Code improvements include a more precise advection scheme (Weighted Average Flux); explicit advection of five hydrometeors, and state-of-the-art parameterization schemes for radiation, convection, boundary layer turbulence and soil processes (also with possible choice among different available schemes). The operational implementation of the new code into the SIMM model chain, which requires the development of a parallel version, will be achieved during 2009. In view of this goal, the comparative verification of the different model versions' skill represents a fundamental task. On this purpose, it has been decided to evaluate the performance improvement of the new BOLAM code (in the available serial version, hereinafter BOLAM 2007) with respect to the version with the Kain-Fritsch scheme (hereinafter KF version) and to the older one employing the Kuo scheme (hereinafter Kuo version). In the present work, verification of precipitation forecasts from the three BOLAM versions is carried on in a case study approach. The intense rainfall episode occurred on 10th - 17th December 2008 over Italy has been considered. This event produced indeed severe damages in Rome and its surrounding areas. Objective and subjective verification methods have been employed in order to evaluate model performance against an observational dataset including rain gauge observations and satellite imagery. Subjective comparison of observed and forecast precipitation fields is suitable to give an overall description of the forecast quality. Spatial errors (e.g., shifting and pattern errors) and rainfall volume error can be assessed quantitatively by means of object-oriented methods. By comparing satellite images with model forecast fields, it is possible to investigate the differences between the evolution of the observed weather system and the predicted ones, and its sensitivity to the improvements in the model code

  13. Sustainable school buildings: design-management-monitoring, results and weaknesses. The case study of the High School “L. Orsini”, Imola

    Directory of Open Access Journals (Sweden)

    Giacomo Chiesa

    2015-04-01

    Full Text Available The paper analyses, seven years after the completion of construction works, the case study of the High School "L.Orsini" in Imola (BO. This sustainable school building was characterised since the design program phase by an innovative approach, based on integration of the various disciplines involved in building design as well as the contribution of a new professional figure, the energy and environmental consultant. This paper describes and analyses results and critical issues from the management and monitoring phases, with focus on the integration between technical systems and building. The high complexity of the applied technical building systems makes this case study of particular interest.

  14. Adequacy of Reporting Results of School Surveys and Nonresponse Effects: A Review of the Literature and a Case Study

    Science.gov (United States)

    Kano, Megumi; Franke, Todd; Afifi, Abdelmonem A.; Bourque, Linda B.

    2008-01-01

    To ensure accurate interpretation of research findings, researchers should report details about their research design, data collection method, and response rates when presenting findings from survey research. A review of 100 peer-reviewed articles reporting the results of survey research on K-12 schools with principals as the designated…

  15. Effect of consanguinity on birth defects in Saudi women; results from a nested case-control study

    DEFF Research Database (Denmark)

    Majeed-Saidan, Muhammad Ali; Ammari, Amer N; AlHashem, Amal M;

    2015-01-01

    BACKGROUND: The role of consanguinity in the etiology of structural birth defects outside of chromosomal and inherited disorders has always been debated. We studied the independent role of consanguinity on birth defects in Saudi women with a high prevalence of consanguineous marriages. METHODS: T...

  16. Effects of earthquakes on the deep repository for spent fuel in Sweden based on case studies and preliminary model results

    Energy Technology Data Exchange (ETDEWEB)

    Baeckblom, Goeran [Conrox, Djursholm (Sweden); Munier, Raymond [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden)

    2002-06-01

    The Baltic Shield is one of the most stable areas in the world. Earthquakes have only on a few occasions exceeded magnitude 4 in Sweden in modern times. The safety case for a deep repository for spent fuel however includes an earthquake scenario due to the following reason: Earthquakes with much greater magnitudes occurred in northern Sweden during the most recent deglaciation period some 9,000 - 10,000 years ago when re-activated faults ruptured the surface. One of the most prominent evidences is the Paervie fault in Lapland, Sweden. The displacements exceeded 10 m in places and occurred over distances of around 150 km. The deep repository is designed to keep radiation well below the natural, ambient radiation for any time in the future. The safety function is achieved by a combination of engineered and natural barriers. One important safety issue is that future displacements in the rock should be less than 0.1 m at the precise location where the engineered canisters containing the waste are emplaced in the rock. Larger displacements could damage the canister that is designed to be tight for several 100,000 of years. SKB now re-visits the issues of seismic effects on underground facilities to supplement and update previous work. The project Effects of Earthquakes on Underground Facilities aims to re-compile field evidences of seismic damage on underground facilities, to shed additional light on the matter of friction loss in bedrock due to water-level changes and finally to find suitable ways to inform concerned citizens on the matter. The fact-finding was carried out in the form of interviews, literature surveys, Internet searches and by sending letters to some 60 organisations and researchers asking for co-operation. The most important conclusions are: Earthquake impact during the pre-closure phase: Damage due to shaking in an underground facility may occur if the peak ground acceleration exceeds 2 m/s{sup 2}. Sweden is located in the Baltic Shield that is

  17. Results of case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria

    International Nuclear Information System (INIS)

    The raised incidence of leukaemia, particularly, and non-Hodgkin's lymphoma among children near Sellafield was associated with paternal employment and recorded external dose of whole body penetrating radiation during work at the plant before conception. The association can explain statistically the observed geographical excess. This result suggests an effect of ionising radiation on fathers that may be leukaemogenic in their offspring, though other, less likely, explanations are possible. (author)

  18. Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) is Improving: Results from a Case Control Study and Literature Review

    OpenAIRE

    Yan Yuen, Sai; Krizova, Adriana; Ouimet, Janine M; Pope, Janet E

    2008-01-01

    Objectives For women who suffer from systemic lupus erythematosus (SLE), pregnancy can be a concern, placing the mother and fetus at risk. Our objectives were to assess the risk of adverse pregnancy outcome, disease flares, fertility rate, and co-morbidities in SLE women compared to healthy controls. We also systematically reviewed the literature available on pregnancy outcome in SLE to compare our results to other published data. Our hypothesis was that pregnancy outcome in SLE is improving ...

  19. Time Series Properties and Their Influence on the Results of Price Transmission – Case Study of the Czech Pork Market

    Directory of Open Access Journals (Sweden)

    L. Rumánkova

    2012-12-01

    Full Text Available This paper deals with an examination of the selected time series and an examination of price transmission in the selected agri-food chain. The analysis is connected with the working question of whether the selection of time series influences the results of price transmission. The analysis is focused on the pork agri-food chain in the Czech Republic; the time series of farm-gate price, wholesale price and consumer price is examined. First of all, the main properties of the selected time series are examined; subsequently, price transmissions based on time series of different frequency and in different periods are analyzed. The price transmission analysis is based on multivariate time series analysis; to be precise, the Vector error correction model and co-integration analysis are employed. The analysis shows that the choice of time series of different frequency should not significantly influence the results of price transmission, whereas the choice of time period might be crucial.The results presented in this paper are outputs of the research project “P402/11/P591 Modelling of price transmission and its asymmetry in agri-food chain – theoretical-empirical implications” supported by Czech Science Foundation.

  20. A case study in technology utilization: Industrial products and practices. [summary of benefits to national economy resulting from space programs

    Science.gov (United States)

    1973-01-01

    In pursuit of such missions as Apollo, the National Aeronautics and Space Administration has called into being unique equipment that obviously has little direct application beyond the achievement of mission objectives. Yet, to assume that further direct application of space program hardware is somehow a measure of the industrial benefits accruing to the nation is to misunderstand how the creation of new technology affects modern industrial capability. This document presents a profile of the significant ways in which technological developments in response to aerospace mission requirements have been coupled into industrial practice, with the result being that improved products and processes are now being utilized to benefit the nation.

  1. Development of Combined Biological Technology for Treatment of High-strength Organic Wastewater and Results of Case Studies

    Institute of Scientific and Technical Information of China (English)

    REN Nanqi; WANG Aijie; HAN Hongjun; MA Fang; DING Jie; SHI Yue; ZHAO Dan

    2006-01-01

    Our study group has developed a unique combined biological technology to treat high-strength organic wastewaters from the industries of dyestuff, pharmaceutical, chemical engineering and zymolysis by using the principles of anaerobic ecological niche and bio-phase separation. The study obtained five national invention patents and eight patent equipments.This technology contains four kernel processes - two-phase anaerobic-aerobic process, hydrolysis-acidification-oxidation process, UASBAF-oxidation process, and internal cycling-hydrolysis-oxidation process. Fifteen pilot projects were accomplished in the basins of Tai Lake, Huai River, Liao River and Songhua River, and their total capital investment reached 185.214million Yuan (RMB). Compared to conventional wastewater treatment technology, the innovative technology is more costeffective for high-strength organic wastewater treatment, can save capital investment by 15% -30%, lessen land usage by 20% to 40% and decrease the operating cost by 10% to 25%. The operating cost of treatment per cubic meter industrial wastewater could be below 0.6 to 1.4 Yuan (RMB).

  2. Project management case studies

    CERN Document Server

    Kerzner, Harold R

    2013-01-01

    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  3. Rotordynamic Stability Case Studies

    OpenAIRE

    Choudhury Pranabesh

    2004-01-01

    In this article case studies are presented involving rotordynamic instability of modern high-speed turbomachinery relating the field data to analytical methods. The studies include oil seal related field problems, instability caused by aerodynamic cross-coupling in high-pressure, high-speed compressors, and hydrodynamic bearing instability resulting in subsynchronous vibration of a high-speed turbocharger. It has been shown that the analytical tools not only help in problem diagnostics, bu...

  4. Some further results on incorporating risk factor information in assessing the dependence between paired failure times arising from case-control family studies: an application to prostate cancer.

    Science.gov (United States)

    Hsu, Li; Prentice, Ross L; Stanford, Janet L

    2002-03-30

    In a typical case-control family study, detailed risk factor information is often collected on cases and controls, but not on their relatives for reasons of cost and logistical difficulty in locating the relatives. The impact of missing risk factor information for relatives on estimation of the strength of dependence between the disease risk of pairs of relatives is largely unknown. In this paper, we extend our earlier work on estimating the dependence of ages at onset between paired relatives from case-control family data to include covariates on cases and controls, and possibly relatives. Using population-based case-control families as our basic data structure, we study the effect of missing covariates for relatives and/or cases and controls on the bias of certain dependence parameter estimators via a simulation study. Finally we illustrate various analyses using a case-control family study of early onset prostate cancer. PMID:11870822

  5. Levels of prolactin in relation to coagulation factors and risk of venous thrombosis. Results of a large population-based case-control study (MEGA-study).

    Science.gov (United States)

    Stuijver, Danka J F; Debeij, Jan; van Zaane, Bregje; Dekkers, Olaf M; Smit, Jan W A; Büller, Harry R; Rosendaal, Frits R; Gerdes, Victor E A; Cannegieter, Suzanne C

    2012-09-01

    The pituitary hormone prolactin is thought to influence coagulation. We aimed to study the relation between prolactin levels, coagulation factors and risk of venous thrombosis (VT). We used data from a large population based case-control study into aetiology of first VT (MEGA-study). Prolactin levels were determined in 2,068 patients with VT and 2,785 age- and sex matched control subjects. The relation between levels of coagulation factors and prolactin was studied among the controls. In addition, odds ratios (OR) and 95% confidence intervals (95%CI) were calculated for the risk of VT for different cut-off points of prolactin levels based on percentiles determined in the controls. Restricted analysis was performed among cases in whom blood was sampled within six months after VT. We found a rise in factor VIII and von Willebrand factor with increasing levels of prolactin in the controls. An increased risk of VT was observed when blood was sampled within six months after thrombosis (OR 2.9, 95%CI 1.1-8.1) for prolactin levels above the 99th percentile (42.6 μg/l) relative to levels between the 20th to 80th percentile. When blood was sampled more than six months after VT no clear association could be observed (OR 1.3, 95%CI 0.7-2.3). In conclusion, we found a modest association between prolactin and symptomatic venous thromboembolism, particularly when blood was sampled close to the event. This may be explained by a causal relation or by prolactin being a marker of stress due to the thrombotic event.

  6. Indoor Air Pollution and Delayed Measles Vaccination Increase the Risk of Severe Pneumonia in Children: Results from a Case-Control Study in Mwanza, Tanzania

    Science.gov (United States)

    PrayGod, George; Mukerebe, Crispin; Magawa, Ruth; Jeremiah, Kidola; Török, M. Estée

    2016-01-01

    Background Mortality due to severe pneumonia during childhood in resource-constrained settings is high, but data to provide basis for interventions to improve survival are limited. The objective of this study was to determine the risk factors for severe pneumonia in children aged under five years old in Mwanza, Tanzania. Methods We conducted a case-control study of children aged 2 to 59 months at Sekou-Toure regional hospital in Mwanza City, north-western, Tanzania from May 2013 to March 2014. Cases were children with severe pneumonia and controls were children with other illnesses. Data on demography, social-economical status, nutritional status, environmental factors, vaccination status, vitamin A supplementation and deworming, and nasopharyngeal carriage were collected and analysed using logistic regression. Results 117 patients were included in the study. Of these, 45 were cases and 72 controls. Cases were younger than controls, but there were no differences in social-economic or nutritional status between the two groups. In multiple regression, we found that an increased risk of severe pneumonia was associated with cooking indoors (OR 5.5, 95% CI: 1.4, 22.1), and delayed measles vaccination (OR 3.9, 95% CI: 1.1, 14.8). The lack of vitamin A supplementation in the preceding six month and Enterobacter spp nasopharyngeal carriage were not associated with higher risk of severe pneumonia. Age ≥24 months (OR 0.2, 95% CI: 0.04, 0.8) and not receiving antibiotics before referral (OR 0.3, 95% CI 0.1, 0.9) were associated with lower risk for severe pneumonia. Conclusions Indoor air pollution and delayed measles vaccination increase the risk for severe pneumonia among children aged below five years. Interventions to reduce indoor air pollution and to promote timely administration of measles vaccination are urgently needed to reduce the burden of severe pneumonia in children in Tanzania PMID:27508389

  7. Microsomal triglyceride transfer protein -164 T > C gene polymorphism and risk of cardiovascular disease: results from the EPIC-Potsdam case-cohort study

    Directory of Open Access Journals (Sweden)

    di Giuseppe Romina

    2013-01-01

    Full Text Available Abstract Background The microsomal triglyceride transfer protein (MTTP is encoded by the MTTP gene that is regulated by cholesterol in humans. Previous studies investigating the effect of MTTP on ischemic heart disease have produced inconsistent results. Therefore, we have tested the hypothesis that the rare allele of the -164T > C polymorphism in MTTP alters the risk of cardiovascular disease (CVD, depending on the cholesterol levels. Methods The -164T > C polymorphism was genotyped in a case-cohort study (193 incident myocardial infarction (MI and 131 incident ischemic stroke (IS cases and 1 978 non-cases nested within the European Prospective Investigation into Cancer and Nutrition (EPIC–Potsdam study, comprising 27 548 middle-aged subjects. The Heinz Nixdorf Recall study (30 CVD cases and 1 188 controls was used to replicate our findings. Results Genotype frequencies were not different between CVD and CVD free subjects (P = 0.79. We observed an interaction between the -164T > C polymorphism and total cholesterol levels in relation to future CVD. Corresponding stratified analyses showed a significant increased risk of CVD (HRadditve = 1.38, 95% CI: 1.07 to 1.78 for individuals with cholesterol levels additive was 1.06, 95% CI: 0.33 to 3.40 for individuals in the Heinz Nixdorf Recall study. A borderline significant decrease in CVD risk was observed in subjects with cholesterol levels ≥200 mg/dL (HRadditve = 0.77, 95% CI: 0.58 to 1.03 in the EPIC-Potsdam study. A similar trend was observed in the independent cohort (HRadditve = 0.60, 95% CI: 0.29 to 1.25. Conclusions Our study suggests an interaction between MTTP -164T > C functional polymorphism with total cholesterol levels. Thereby risk allele carriers with low cholesterol levels may be predisposed to an increased risk of developing CVD, which seems to be abolished among risk allele carriers with high cholesterol levels.

  8. Estimates of pandemic influenza vaccine effectiveness in Europe, 2009-2010: results of Influenza Monitoring Vaccine Effectiveness in Europe (I-MOVE multicentre case-control study.

    Directory of Open Access Journals (Sweden)

    Marta Valenciano

    2011-01-01

    Full Text Available BACKGROUND: A multicentre case-control study based on sentinel practitioner surveillance networks from seven European countries was undertaken to estimate the effectiveness of 2009-2010 pandemic and seasonal influenza vaccines against medically attended influenza-like illness (ILI laboratory-confirmed as pandemic influenza A (H1N1 (pH1N1. METHODS AND FINDINGS: Sentinel practitioners swabbed ILI patients using systematic sampling. We included in the study patients meeting the European ILI case definition with onset of symptoms >14 days after the start of national pandemic vaccination campaigns. We compared pH1N1 cases to influenza laboratory-negative controls. A valid vaccination corresponded to >14 days between receiving a dose of vaccine and symptom onset. We estimated pooled vaccine effectiveness (VE as 1 minus the odds ratio with the study site as a fixed effect. Using logistic regression, we adjusted VE for potential confounding factors (age group, sex, month of onset, chronic diseases and related hospitalizations, smoking history, seasonal influenza vaccinations, practitioner visits in previous year. We conducted a complete case analysis excluding individuals with missing values and a multiple multivariate imputation to estimate missing values. The multivariate imputation (n = 2902 adjusted pandemic VE (PIVE estimates were 71.9% (95% confidence interval [CI] 45.6-85.5 overall; 78.4% (95% CI 54.4-89.8 in patients <65 years; and 72.9% (95% CI 39.8-87.8 in individuals without chronic disease. The complete case (n = 1,502 adjusted PIVE were 66.0% (95% CI 23.9-84.8, 71.3% (95% CI 29.1-88.4, and 70.2% (95% CI 19.4-89.0, respectively. The adjusted PIVE was 66.0% (95% CI -69.9 to 93.2 if vaccinated 8-14 days before ILI onset. The adjusted 2009-2010 seasonal influenza VE was 9.9% (95% CI -65.2 to 50.9. CONCLUSIONS: Our results suggest good protection of the pandemic monovalent vaccine against medically attended pH1N1 and no effect of the

  9. Surgical Results in Cases of Sensory Strabismus

    Directory of Open Access Journals (Sweden)

    Ayfle Yeflim Oral

    2011-08-01

    Full Text Available Purpose: To determine horizontal deviation type and to evaluate the correlation between deviation type/etiology and surgical results for sensory strabismus. Patients and Methods: The reports of 29 patients operated for sensory strabismus (12 female, 17 male whose mean age was 22.17±11.52 (range: 4-57 years were evaluated retrospectively. Sixteen cases (55.2% had exotropia (XT and 13 cases (44.8% had esotropia (ET. Etiologies, ages during surgeries, and preoperative/postoperative deviation amounts were noted for the total of the patients as well as for ET and XT groups separately. The results for ET and XT groups were compared statistically using t test. The mean follow-up time was 4.27±3.5 years (range: 4 months-12 years and deviation in ±10 prism diopters (PD in the last visit was considered as success. Results: Etiologies in all cases examined were as follows: anisometropia in 13 (44.8%, trauma in 10 (34.5%, congenital cataracts in 2, and congenital glaucoma, keratoconus, choroidal coloboma, and hypoplastic optic disc in one case each. The visual acuity of the squinting eyes ranged from no light perception to 0.8 logMAR. The mean preoperative deviation was 46.24±19.29 PD, and the mean postoperative deviation decreased to 9.55±11.86 PD in the last visit. When the ET and XT groups were compared, the congenital causes were more common in the ET group (30.75% compared to the XT group (6.25%, otherwise, there was no statistically significant difference in terms of mean age, preoperative and postoperative deviation amounts and follow-up time between the two groups (p>0.05. In contrast, while the surgical success rate was found to be 75.9 % for all cases and 87.5% for the XT group, it was 61.5% for the ET group. Discussion: Despite the deep amblyopia in sensory strabismus, satisfactory surgical results are achieved; nevertheless, the success may be more limited in sensory esotropia particularly due to congenital causes. (Turk J Ophthalmol 2011

  10. Traditional Dietary Pattern Increases Risk of Prostate Cancer in Argentina: Results of a Multilevel Modeling and Bias Analysis from a Case-Control Study

    Directory of Open Access Journals (Sweden)

    Camila Niclis

    2015-01-01

    Full Text Available There is increasing evidence that dietary habits play a role in prostate cancer (PC occurrence. Argentinean cancer risk studies require additional attention because of the singular dietary pattern of this population. A case-control study (147 PC cases, 300 controls was conducted in Córdoba (Argentina throughout 2008–2013. A principal component factor analysis was performed to identify dietary patterns. A mixed logistic regression model was applied, taking into account family history of cancer. Possible bias was evaluated by probabilistic bias analysis. Four dietary patterns were identified: Traditional (fatty red meats, offal, processed meat, starchy vegetables, added sugars and sweets, candies, fats, and vegetable oils, Prudent (nonstarchy vegetables, whole grains, Carbohydrate (sodas/juices and bakery products, and Cheese (cheeses. High adherence to the Traditional (OR 2.82, 95%CI: 1.569–5.099 and Carbohydrate Patterns (OR 2.14, 95%CI: 1.470–3.128 showed a promoting effect for PC, whereas the Prudent and Cheese Patterns were independent factors. PC occurrence was also associated with family history of PC. Bias adjusted ORs indicate that the validity of the present study is acceptable. High adherence to characteristic Argentinean dietary patterns was associated with increased PC risk. Our results incorporate original contributions to knowledge about scenarios in South American dietary patterns and PC occurrence.

  11. Risk of lung cancer associated with six types of chlorinated solvents: results from two case-control studies in Montreal, Canada

    Science.gov (United States)

    Methods: Two case-control studies of occupation and lung cancer were conducted in Montreal, including 2,016 cases and 2,001 population controls. Occupational exposure to a host of agents was evaluated using a combination of subject-reported job history and expert assessment. We e...

  12. Effectiveness of Trivalent Inactivated Influenza Vaccine in Children Estimated by a Test-Negative Case-Control Design Study Based on Influenza Rapid Diagnostic Test Results.

    Science.gov (United States)

    Shinjoh, Masayoshi; Sugaya, Norio; Yamaguchi, Yoshio; Tomidokoro, Yuka; Sekiguchi, Shinichiro; Mitamura, Keiko; Fujino, Motoko; Shiro, Hiroyuki; Komiyama, Osamu; Taguchi, Nobuhiko; Nakata, Yuji; Yoshida, Naoko; Narabayashi, Atsushi; Myokai, Michiko; Sato, Masanori; Furuichi, Munehiro; Baba, Hiroaki; Fujita, Hisayo; Sato, Akihiro; Ookawara, Ichiro; Tsunematsu, Kenichiro; Yoshida, Makoto; Kono, Mio; Tanaka, Fumie; Kawakami, Chiharu; Kimiya, Takahisa; Takahashi, Takao; Iwata, Satoshi

    2015-01-01

    We assessed vaccine effectiveness (VE) against medically attended, laboratory-confirmed influenza in children 6 months to 15 years of age in 22 hospitals in Japan during the 2013-14 season. Our study was conducted according to a test-negative case-control design based on influenza rapid diagnostic test (IRDT) results. Outpatients who came to our clinics with a fever of 38 °C or over and had undergone an IRDT were enrolled in this study. Patients with positive IRDT results were recorded as cases, and patients with negative results were recorded as controls. Between November 2013 and March 2014, a total of 4727 pediatric patients (6 months to 15 years of age) were enrolled: 876 were positive for influenza A, 66 for A(H1N1)pdm09 and in the other 810 the subtype was unknown; 1405 were positive for influenza B; and 2445 were negative for influenza. Overall VE was 46% (95% confidence interval [CI], 39-52). Adjusted VE against influenza A, influenza A(H1N1)pdm09, and influenza B was 63% (95% CI, 56-69), 77% (95% CI, 59-87), and 26% (95% CI, 14-36), respectively. Influenza vaccine was not effective against either influenza A or influenza B in infants 6 to 11 months of age. Two doses of influenza vaccine provided better protection against influenza A infection than a single dose did. VE against hospitalization influenza A infection was 76%. Influenza vaccine was effective against influenza A, especially against influenza A(H1N1)pdm09, but was much less effective against influenza B.

  13. NOx trade. Case studies

    International Nuclear Information System (INIS)

    Some of the questions with respect to the trade of nitrogen oxides that businesses in the Netherlands have to deal with are dealt with: should a business buy or sell rights for NOx emission; which measures must be taken to reduce NOx emission; how much must be invested; and how to deal with uncertainties with regard to prices. Simulations were carried out with the MOSES model to find the answers to those questions. Results of some case studies are presented, focusing on the chemical sector in the Netherlands. Finally, the financial (dis)advantages of NOx trade and the related uncertainties for a single enterprise are discussed

  14. Cooperation and organization in decision making : a more decisive road safety policy ? : results from a multiple case study in the Netherlands.

    NARCIS (Netherlands)

    Bax, C.

    2005-01-01

    This study examines the administrative processes that led to the implementation of road safety measures in Dutch Regional Traffic and Transport Plans. The design of the study is a multiple case study in six regions in the Netherlands. The road safety policy is evaluated by looking at the effectivene

  15. Role of previous hospitalization in clinically-significant MRSA infection among HIV-infected inpatients: results of a case-control study

    Directory of Open Access Journals (Sweden)

    Festa Anna

    2007-04-01

    Full Text Available Abstract Background HIV-infected subjects have high incidence rates of Staphylococcus aureus infections, with both methicillin-susceptible and methicillin-resistant (MRSA strains. Possible explanations could include the high burden of colonization, the behavioral risk factors, and the frequent exposures to health care facilities of HIV-infected patients. The purpose of the study was to assess the risk factors for clinically- significant methicillin-resistant Staphylococcus aureus (CS-MRSA infections in HIV-infected patients admitted to Infectious Diseases Units. Methods From January 1, 2002 to December 31, 2005, we conducted a retrospective case-control (1:2 study. We identified all the cases of CS-MRSA infections in HIV-infected patients admitted to the National Institute for Infectious Diseases (INMI "Lazzaro Spallanzani" in the 4-year study period. A conditional logistic regression model was used to identify risk factors for CS-MRSA infection. Results We found 27 CS-MRSA infections, i.e. 0.9 CS-MRSA infections per 100 HIV-infected individuals cared for in our Institute. At multivariate analysis, independent predictors of CS-MRSA infection were cumulative hospital stay, invasive procedures in the previous year, and low CD4 cell count. Particularly, the risk for CS-MRSA increased by 14% per an increase of 5 days hospitalization in the previous year. Finally, we identified a low frequency of community-acquired MRSA infections (only 1 of 27; 3.7% among HIV-infected patients. Conclusion Clinicians should be aware of the risk for CS-MRSA infection in the clinical management of HIV-infected patients, especially in those patients with a low CD4 cell count, longer previous hospital stay, and previous invasive procedures.

  16. Role of previous hospitalization in clinically-significant MRSA infection among HIV-infected inpatients: results of a case-control study

    Science.gov (United States)

    Drapeau, Cecilia MJ; Angeletti, Claudio; Festa, Anna; Petrosillo, Nicola

    2007-01-01

    Background HIV-infected subjects have high incidence rates of Staphylococcus aureus infections, with both methicillin-susceptible and methicillin-resistant (MRSA) strains. Possible explanations could include the high burden of colonization, the behavioral risk factors, and the frequent exposures to health care facilities of HIV-infected patients. The purpose of the study was to assess the risk factors for clinically- significant methicillin-resistant Staphylococcus aureus (CS-MRSA) infections in HIV-infected patients admitted to Infectious Diseases Units. Methods From January 1, 2002 to December 31, 2005, we conducted a retrospective case-control (1:2) study. We identified all the cases of CS-MRSA infections in HIV-infected patients admitted to the National Institute for Infectious Diseases (INMI) "Lazzaro Spallanzani" in the 4-year study period. A conditional logistic regression model was used to identify risk factors for CS-MRSA infection. Results We found 27 CS-MRSA infections, i.e. 0.9 CS-MRSA infections per 100 HIV-infected individuals cared for in our Institute. At multivariate analysis, independent predictors of CS-MRSA infection were cumulative hospital stay, invasive procedures in the previous year, and low CD4 cell count. Particularly, the risk for CS-MRSA increased by 14% per an increase of 5 days hospitalization in the previous year. Finally, we identified a low frequency of community-acquired MRSA infections (only 1 of 27; 3.7%) among HIV-infected patients. Conclusion Clinicians should be aware of the risk for CS-MRSA infection in the clinical management of HIV-infected patients, especially in those patients with a low CD4 cell count, longer previous hospital stay, and previous invasive procedures. PMID:17470274

  17. Wind Energy Study and Energy Cost of Wind Electricity Generation in Nigeria: Past and Recent Results and a Case Study for South West Nigeria

    Directory of Open Access Journals (Sweden)

    Oluseyi O. Ajayi

    2014-12-01

    Full Text Available The study assessed the wind energy potential of ten selected sites in the south western region of Nigeria and carried out a cost benefit analysis of wind power generation at those sites. Twenty four years’ (1987 to 2010 wind speed data at 10 m height obtained from the Nigerian meteorological agency were employed to classify the sites wind profiles for electricity generation. The energy cost analysis of generating wind electricity from the sites was also carried out. The outcome showed that sites in Lagos and Oyo States were adequately suited for large scale generation with average wind speeds ranged between 2.9 and 5.8 m/s. Those from other sites may be suitable for small scale generation or as wind farms, with several small turbines connected together, to generate large enough wind power. The turbine matching results shows that turbines cut-in and rated wind speeds of between 2.0 and 3.0 m/s, and between 10 and 12.0 m/s respectively will be very suited to all the sites, particularly those in locations outside Lagos and Oyo States. The energy cost analysis shows that generation cost can be as low as 0.02 €/kWh and as high as 5.03/kWh, depending on the turbine model employed.

  18. Implementation of a collaborative care model for the treatment of depression and anxiety in a community health center: results from a qualitative case study

    Directory of Open Access Journals (Sweden)

    Eghaneyan BH

    2014-11-01

    Full Text Available Brittany H Eghaneyan,1 Katherine Sanchez,2 Diane B Mitschke2 1Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA; 2School of Social Work, The University of Texas at Arlington, Arlington, TX, USA Background: The collaborative care model is a systematic approach to the treatment of depression and anxiety in primary care settings that involves the integration of care managers and consultant psychiatrists, with primary care physician oversight, to more proactively manage mental disorders as chronic diseases, rather than treating acute symptoms. While collaborative care has been shown to be more effective than usual primary care in improving depression outcomes in a number of studies, less is known about the factors that support the translation of this evidence-based intervention to real-world program implementation. The purpose of this case study was to examine the implementation of a collaborative care model in a community based primary care clinic that primarily serves a low-income, uninsured Latino population, in order to better understand the interdisciplinary relationships and the specific elements that might facilitate broader implementation. Methods: An embedded single-case study design was chosen in order to thoroughly examine the components of one of several programs within a single organization. The main unit of analysis was semi-structured interviews that were conducted with seven clinical and administrative staff members. A grounded theory approach was used to analyze the interviews. Line-by-line initial coding resulted in over 150 initial codes, which were clustered together to rebuild the data into preliminary categories and then divided into four final categories, or main themes. Results: Four unique themes about how the implementation of a collaborative care model worked in this setting emerged from the interviews: organizational change, communication, processes and outcomes of the program, and barriers to

  19. Voluntary agreements, implementation and efficiency. European relevance of case study results. Reflections on transferability to voluntary agreement schemes at the European level

    Energy Technology Data Exchange (ETDEWEB)

    Helby, Peter

    2000-04-01

    As a policy instrument, voluntary agreements often fascinate policy-makers.This is fuelled by a number of assumed advantages, such as the opportunity for co-operation rather than confrontation, speed and flexibility and the cost-effectiveness. Some advantages might even be accentuated at the European level: Co-operation has added advantage at the European level where the culture of consensus decision is strong. Flexibility is extra attractive for policy makers dealing with an economy less homogeneous than the average national economy. Speed is certainly welcomed by policy-makers otherwise faced with the slow-winding European legislative process. Cost-effectiveness is eagerly sought by European policy makers facing tight administrative budgets and staff limits. This report examines lessons from the VAIE case studies that may be useful to policy makers engaged in the development of voluntary approaches at the European level. These case studies are about voluntary agreement schemes for industrial energy efficiency deployed in Denmark, France, Germany, Netherlands, and Sweden. For a summary of these case studies, please refer to the the VAIE final report. More detailed information is available in the VAIE national reports. It needs to be emphasised that the empirical base is very narrow. The 'lessons' presented can only be hypotheses, based on an inductive leap from a very narrow experience. The reader will need to check these hypotheses against her own broader experience and personal judgement. According to the principle of subsidiarity, voluntary agreements should be implemented at the European level only if that would have significant advantage over national action. Action at the European level, rather than the national level, would have these potential advantages: Being more consistent with the development of the single market; Allowing higher demands on energy efficiency without negative effect on competitiveness and employment; Stimulating company

  20. Impact of High-Cut-Off Dialysis on Renal Recovery in Dialysis-Dependent Multiple Myeloma Patients: Results from a Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Hans U Gerth

    Full Text Available High-cut-off hemodialysis (HCO-HD can effectively reduce high concentrations of circulating serum free light chains (sFLC in patients with dialysis-dependent acute kidney injury (AKI due to multiple myeloma (MM. Therefore, the aim of this study was to analyze renal recovery in a retrospective single-center cohort of dialysis-dependent MM patients treated with either conventional HD (conv. HD or HCO-HD.The final cohort consisted of 59 patients treated with HCO-HD (n = 42 or conv. HD (n = 17. A sustained sFLC response was detected in a significantly higher proportion of HCO-HD patients (83.3% compared with conv. HD patients (29.4%; p = 0.007. The median duration of sFLC required to reach values <1000 mg/l was 14.5 days in the HCO-HD group and 36 days in the conv. HD group. The corresponding rates of renal recovery were 64.3% and 29.4%, respectively (chi-squared test, p = 0.014. Multivariate regression and decision tree analysis (recursive partitioning revealed HCO-HD (adjusted odds ratio [OR] 6.1 [95% confidence interval (CI 1.5-24.5], p = 0.011 and low initial uric acid values (adjusted OR 1.3 [95%CI 1.0-1.7], p = 0.045 as independent and paramount variables associated with a favorable renal outcome.In summary, the results from this retrospective case-control study suggest in addition to novel agent-based chemotherapy a benefit of HCO-HD in sFLC removal and renal outcome in dialysis-dependent AKI secondary to MM. This finding was especially pertinent in patients with low initial uric acid values, resulting in a promising renal recovery rate of 71.9%. Further prospective studies are warranted.

  1. The effects of different input data and their spatial resolution on the results obtained from a conceptual nutrient emissions model: the River Stör case study

    Science.gov (United States)

    Venohr, Markus; Behrendt, Horst; Kluge, Winfrid

    2005-11-01

    This paper focuses on the influences of different data sources, and the variation in spatial resolution of input data and analysis, on the calculated nutrient emissions using the conceptual model MONERIS. MONERIS calculates both nitrogen and phosphorus emissions from point and diffuse sources and the riverine nutrient retention. By subtracting the retention from the emissions, a riverine nutrient load was estimated and compared with the observed nutrient river load. All calculations were conducted for the period from 1991 to 1993.The River Stör, with a catchment area of 1135 km2, located in a postglacial lowland landscape in northern Germany, was chosen as a case study area. Two different data sets (e.g. land use, soil type or wastewater treatment plant inventory) were used: a commonly available standard data set (German or European maps) and a more detailed set with a higher spatial resolution derived from several studies at the Ecosystem Research Centre in Kiel. Initially, both data sets were used to apply MONERIS to the total catchment. The results were compared to adapt some of the free model-parameters to the conditions in the relatively small lowland river catchment.Using the standard data set, total nutrient emissions of 2320 tons year-1 of nitrogen and 96 tons year-1 phosphorus were calculated. The detailed data set yielded slightly higher emissions for nitrogen (2420 tons year-1) and for phosphorus (102 tons year-1). According to the spatial resolution, the proportion of the area of tile drainages and sandy soils derived from the different data sets varies considerably. This causes great differences in the total nutrient emissions estimated by the two approaches. Comparing the observed and the calculated nutrient loads, reliable results for catchments larger than 50 km2, or third-order streams, could be shown. Copyright

  2. Aberrations Involving Chromosome 1 as a Possible Predictor of Odds Ratio for Colon Cancer--Results from the Krakow Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Aleksander Galas

    Full Text Available There is still an open question how to predict colorectal cancer risk before any morphological changes appear in the colon.The purpose was to investigate aberrations in chromosomes 1, 2 and 4 in peripheral blood lymphocytes analyzed by fluorescence in situ hybridization technique as a tool to assess the likelihood of colorectal cancer.A hospital-based case-control study included 20 colon cancer patients and 18 hospital-based controls. Information about potential covariates was collected by interview. The frequency of stable and unstable chromosome aberrations in chromosome 1, 2 and 4 was assessed by fluorescence in situ hybridization technique.Colorectal cancer patients, as compared to controls, had a relatively higher frequency of chromosome 1 translocations (median: 3.5 versus 1.0 /1000 cells, p = 0.006, stable aberrations (3.8 versus 1.0 /1000 cells, p = 0.007 and total aberrations (p = 0.009. There were no differences observed for chromosomes 2 and 4. Our results showed an increase in the odds of having colon cancer by about 50-80% associated with an increase by 1/1000 cells in the number of chromosome 1 aberrations.The results revealed that the frequency of chromosomal aberrations, especially translocations in chromosome 1, seems to be a promising method to show a colon cancer risk. Additionally, our study suggests the reasonableness of use of biomarkers such as chromosome 1 aberrations in peripheral blood lymphocytes in screening prevention programs for individuals at higher colon cancer risk to identify those who are at increased risk and require more frequent investigations, e.g. by sigmoidoscopy.

  3. Association of JAK-STAT pathway related genes with lymphoma risk: results of a European case-control study (EpiLymph)

    OpenAIRE

    Butterbach, Katja; Beckmann, Lars; de Sanjosé, Silvia; Benavente, Yolanda; Becker, Nikolaus; Foretova, Lenka; Maynadié, Marc; Cocco, Pierluigi; Staines, Anthony; Boffetta, Paolo; Brennan, Paul; Nieters, Alexandra

    2011-01-01

    Abstract Previous studies have suggested an important role of the JAK-STAT signalling pathway in tumour development. Therefore, we explored genetic variants in JAK-STAT pathway associated genes with lymphoma risk. In samples of the EpiLymph case-control study we genotyped 1536 single nucleotide polymorphisms (SNPs) using GoldenGate BeadArrayTM Technology (Illumina, San Diego, CA). Here, we report the associations between selected SNPs and haplotypes of the JAK-STAT pathway and risk...

  4. Cumulative occupational lumbar load and lumbar disc disease – results of a German multi-center case-control study (EPILIFT)

    OpenAIRE

    Michaelis Martina; Luttmann Alwin; Linhardt Oliver; Hofmann Friedrich; Haerting Johannes; Grifka Joachim; Elsner Gine; Ditchen Dirk; Ellegast Rolf; Jäger Matthias; Bergmann Annekatrin; Seidler Andreas; Petereit-Haack Gabriela; Schumann Barbara; Bolm-Audorff Ulrich

    2009-01-01

    Abstract Background The to date evidence for a dose-response relationship between physical workload and the development of lumbar disc diseases is limited. We therefore investigated the possible etiologic relevance of cumulative occupational lumbar load to lumbar disc diseases in a multi-center case-control study. Methods In four study regions in Germany (Frankfurt/Main, Freiburg, Halle/Saale, Regensburg), patients seeking medical care for pain associated with clinically and radiologically ve...

  5. Association between GSTM1 and GSTT1 polymorphisms and esophageal squamous cell carcinoma: results from a case-control study in Kashmir, India.

    Science.gov (United States)

    Makhdoomi, Muzamil Ashraf; Shah, Idrees Ayoub; Bhat, Gulzar Ahmad; Amin, Shajrul; Lone, Mohd Maqbool; Islami, Farhad; Dar, Nazir Ahmad

    2015-04-01

    Polymorphisms in glutathione-S-transferases (GSTs), the phase II xenobiotic detoxifying enzymes, have been associated with increased cancer risk. In this study, we assessed the association of functional polymorphisms in GSTM1 and GSTT1 with esophageal cancer in Kashmir, India, an area with a high incidence of esophageal squamous cell carcinoma (ESCC). We analyzed genotypes of GSTM1 and GSTT1 using a multiplex PCR in 492 pairs of ESCC cases and individually matched controls. The associations between polymorphisms in these genes and ESCC risk were examined by conditional logistic regression models adjusted for multiple potential confounders. In addition, the interaction between these genes and several environmental exposures with regard to ESCC risk was assessed. Our results showed an association between the GSTT1 null genotype and ESCC risk (odds ratio (OR) = 1.58; 95% confidence interval (CI) 1.04-2.39). Although GSTM1 alone was not associated with ESCC risk, individuals with the GSTM1 (-)/GSTT1 (+) genotype showed an inverse relation with ESCC risk (OR = 0.55; 95% CI 0.32-0.93), compared to GSTM1 (+)/GSTT1 (+) individuals. We found a significant interaction between the GSTT1 and GSTM1 genotypes with regard to ESCC risk (P = 0.001); however, there were no interactions between environmental factors and GSTT1 and GSTM1 genotypes. This study indicates that GSTT1 null genotype is associated with ESCC risk in Kashmiri population. The association between GSTM1 and ESCC risk needs further investigations. Interactions of these genotypes with environmental exposures should be examined in multicentric studies with bigger sample sizes.

  6. Transient dynamics study on casing deformation resulted from lost circulation in low-pressure formation in the Yuanba Gasfield, Sichuan Basin

    Directory of Open Access Journals (Sweden)

    Chen Shen

    2015-10-01

    Full Text Available In the course of completion of an ultra-deep well newly drilled in the Yuanba Gasfield, Sichuan Basin, long-section and large-scale deformation occurred in the heavy casing section and nickel base alloy casing section of the sealing Triassic limestone interval, so a new hole had to be sidetracked, which impels us to rediscover the applicability of conventional drilling and completion technology in ultra-deep wells. In this paper, based on the borehole condition and field operation data of this well, the borehole pressure field variation initiated by lost circulation in the low-pressure formation was analyzed from the perspective of dynamics, then, the variation pattern of differential pressure inside and outside the well bore at different time intervals was depicted, and the primary cause of such complication was theoretically revealed, i.e., the pressure wave generated by instant lost circulation in low-pressure formation would result in redistribution of pressure inside the downhole confined space, and then the crush of casing in the vicinity of local low-pressure areas. Pertinent proposals for avoiding these kinds of engineering complexities were put forward: ① when downhole sealing casing operation is conducted in open hole completion, liner completion or perforated hole, the potential damage of lost circulation to casing should be considered; ② the downhole sealing point and sealing mode should be selected cautiously: the sealing point had better be selected in the section with good cementing quality or as close to the casing shoe as possible, and the sealing mode can be either cement plug or mechanical bridge plug. This paper finally points out that good cementing quality plays an important role in preventing this type of casing deformation.

  7. ASSESSING THE CONSERVATION STATUS OF EUROPEAN UNION HABITATS – RESULTS OF THE COMMUNITY REPORT WITH A CASE STUDY OF THE GERMAN NATIONAL REPORT

    Directory of Open Access Journals (Sweden)

    S. BALZER

    2010-01-01

    Full Text Available The EU Habitats Directive requires all member states to report every 6 years on the implementation of the Directive. The report covering the period 2000 – 2006 included for the first time an assessment of the conservation status of the habitats and species listed on annexes I, II, IV & V of the Habitats Directive following an agreed format. Based on national reports submitted from member States the European Topic Centre on Biological Diversity has prepared assessments for each biogeographical region at EU-level. The majority of the habitats of Annex I are not at favourable status although there is much variation both between countries and regions and between habitats. The results will be discussed at European level and at member state level with a case study of the German national report. At the same time a number of methodical problems became apparent both in Germany and at EU-level. Work is already under way to improve the next report for the period 2007 – 2012. The dimension of management needs, threats and pressures and the time scale for improvements of the conservation status are discussed. Habitats linked to agriculture appear to be particularly unfavourable.

  8. Human bocaviruses are not significantly associated with gastroenteritis: results of retesting archive DNA from a case control study in the UK.

    Directory of Open Access Journals (Sweden)

    Sameena Nawaz

    Full Text Available Gastroenteritis is a common illness causing considerable morbidity and mortality worldwide. Despite improvements in detection methods, a significant diagnostic gap still remains. Human bocavirus (HBoVs, which are associated with respiratory infections, have also frequently been detected in stool samples in cases of gastroenteritis, and a tentative association between HBoVs, and in particular type-2 HBoVs, and gastroenteritis has previously been made. The aim of this study was to determine the role of HBoVs in gastroenteritis, using archived DNA samples from the case-control Infectious Intestinal Disease Study (IID. DNA extracted from stool samples from 2,256 cases and 2,124 controls were tested for the presence of HBoV DNA. All samples were screened in a real time PCR pan-HBoV assay, and positive samples were then tested in genotype 1 to 3-specific assays. HBoV was detected in 7.4% but no significantly different prevalence was observed between cases and controls. In the genotype-specific assays 106 of the 324 HBoV-positive samples were genotyped, with HBoV-1 predominantly found in controls whilst HBoV-2 was more frequently associated with cases of gastroenteritis (p<0.01. A significant proportion of HBoV positives could not be typed using the type specific assays, 67% of the total positives, and this was most likely due to low viral loads being present in the samples. However, the distribution of the untyped HBoV strains was no different between cases and controls. In conclusion, HBoVs, including HBoV-2 do not appear to be a significant cause of gastroenteritis in the UK population.

  9. The increased risk of road crashes in attention deficit hyperactivity disorder (ADHD adult drivers: driven by distraction? Results from a responsibility case-control study.

    Directory of Open Access Journals (Sweden)

    Kamal El Farouki

    Full Text Available Both distractions (external and internal and attention-deficit/hyperactivity disorder (ADHD are serious risk factors for traffic crashes and injuries. However, it is still unknown if ADHD (a chronic condition modifies the effect of distractions (irregular hazards on traffic crashes. The objective of this study was to assess the effects of distractions and ADHD on traffic crash responsibility.A responsibility case-control study was conducted in the adult emergency department of Bordeaux University Hospital, France. Subjects were recruited among drivers injured in a motor vehicle crash between April 2010 and August 2011. Responsibility levels were estimated using a standardized method. Frequencies of exposures were compared between drivers responsible and drivers not responsible for the crash. Independent risk factors were identified using a multivariate logistic regression including test interactions between distractions and ADHD.A total of 777 subjects were included in the analysis. Factors associated with responsibility were distraction induced by an external event (adjusted OR (aOR = 1.47; 95% confidence interval (CI [1.06-2.05], distraction induced by an internal thought (aOR = 2.38; CI: [1.50-3.77] and ADHD (aOR = 2.18 CI: [1.22-3.88]. The combined effect of ADHD and external distractions was strongly associated with responsibility for the crash (aOR = 5.79 CI: [2.06-16.32]. Interaction assessment showed that the attributable proportion due to the interaction among participants with both exposures was 68%.Adults with ADHD are a population at higher risk of being responsible for a road traffic crash when exposed to external distractions. This result reinforces the need to diagnose adult ADHD and to include road safety awareness messages delivered by the physician. Developing advanced driver assistance systems devoted to the management of attention lapses is also increasingly relevant for these drivers.

  10. A Case Study of Gender Bias at the Postdoctoral Level in Physics, and its Resulting Impact on the Academic Career Advancement of Females

    OpenAIRE

    Towers, S.

    2008-01-01

    This case study of a typical U.S. particle physics experiment explores the issues of gender bias and how it affects the academic career advancement prospects of women in the field of physics beyond the postdoctoral level; we use public databases to study the career paths of the full cohort of 57 former postdoctoral researchers on the Run II Dzero experiment to examine if males and females were treated in a gender-blind fashion on the experiment. The study finds that the female researchers wer...

  11. Variation in Breast Cancer–Risk Factor Associations by Method of Detection: Results From a Series of Case-Control Studies

    OpenAIRE

    Sprague, Brian L.; Gangnon, Ronald E.; Hampton, John M.; Egan, Kathleen M.; Titus, Linda J.; Kerlikowske, Karla; Remington, Patrick L; Newcomb, Polly A.; Trentham-Dietz, Amy

    2015-01-01

    Concerns about breast cancer overdiagnosis have increased the need to understand how cancers detected through screening mammography differ from those first detected by a woman or her clinician. We investigated risk factor associations for invasive breast cancer by method of detection within a series of case-control studies (1992–2007) carried out in Wisconsin, Massachusetts, and New Hampshire (n = 15,648 invasive breast cancer patients and 17,602 controls aged 40–79 years). Approximately half...

  12. Human Bocaviruses Are Not Significantly Associated with Gastroenteritis: Results of Retesting Archive DNA from a Case Control Study in the UK

    OpenAIRE

    Sameena Nawaz; Allen, David J.; Farah Aladin; Christopher Gallimore; Miren Iturriza-Gómara

    2012-01-01

    Gastroenteritis is a common illness causing considerable morbidity and mortality worldwide. Despite improvements in detection methods, a significant diagnostic gap still remains. Human bocavirus (HBoV)s, which are associated with respiratory infections, have also frequently been detected in stool samples in cases of gastroenteritis, and a tentative association between HBoVs, and in particular type-2 HBoVs, and gastroenteritis has previously been made. The aim of this study was to determine th...

  13. Social determinants of equity in access to healthcare for tuberculosis patients in Republic of Macedonia – results from a case-control study

    OpenAIRE

    Dance Gudeva Nikovska; Fimka Tozija

    2014-01-01

    Background Health is a complex phenomenon and equity as a basic human right an integral part of constitutions in almost all countries in the world. In Republic of Macedonia (RM), Tuberculosis (TB) is clustered regionally and in certain ethnic groups. The main objective of this study was to analyze Social Determinants of Health (SDH) and equity in access to healthcare services for TB patients in RM, aimed at complex analysis of factors that cause inequities. Methods Case-cont...

  14. Prevalence and contribution of BRCA1 mutations in breast cancer and ovarian cancer: Results from three US population-based case-control studies of ovarian cancer

    Energy Technology Data Exchange (ETDEWEB)

    Whittemore, A.S.; Gong, G.; Itnyre, J. [Stanford Univ. School of Medicine, CA (United States)

    1997-03-01

    We investigate the familial risks of cancers of the breast and ovary, using data pooled from three population-based case-control studies of ovarian cancer that were conducted in the United States. We base estimates of the frequency of mutations of BRCA1 (and possibly other genes) on the reported occurrence of breast cancer and ovarian cancer in the mothers and sisters of 922 women with incident ovarian cancer (cases) and in 922 women with no history of ovarian cancer (controls). Segregation analysis and goodness-of-fit testing of genetic models suggest that rare mutations (frequency .0014; 95% confidence interval .0002-.011) account for all the observed aggregation of breast cancer and ovarian cancer in these families. The estimated risk of breast cancer by age 80 years is 73.5% in mutation carriers and 6.8% in noncarriers. The corresponding estimates for ovarian cancer are 27.8% in carriers and 1.8% in noncarriers. For cancer risk in carriers, these estimates are lower than those obtained from families selected for high cancer prevalence. The estimated proportion of all U.S. cancer diagnoses, by age 80 years, that are due to germ-line BRCA1 mutations is 3.0% for breast cancer and 4.4% for ovarian cancer. Aggregation of breast cancer and ovarian cancer was less evident in the families of 169 cases with borderline ovarian cancers than in the families of cases with invasive cancers. Familial aggregation did not differ by the ethnicity of the probands, although the number of non-White and Hispanic cases (N = 99) was sparse. 14 refs., 3 figs., 6 tabs.

  15. Associations between Burkitt lymphoma among children in Malawi and infection with HIV, EBV and malaria: results from a case-control study.

    Directory of Open Access Journals (Sweden)

    Nora Mutalima

    Full Text Available BACKGROUND: Burkitt lymphoma, a childhood cancer common in parts of sub-Saharan Africa, has been associated with Epstein Barr Virus (EBV and malaria, but its association with human immunodeficiency virus (HIV is not clear. METHODOLOGY/PRINCIPAL FINDINGS: We conducted a case-control study of Burkitt lymphoma among children (aged < or = 15 years admitted to the pediatric oncology unit in Blantyre, Malawi between July 2005 and July 2006. Cases were 148 children diagnosed with Burkitt lymphoma and controls were 104 children admitted with non-malignant conditions or cancers other than hematological malignancies and Kaposi sarcoma. Interviews were conducted and serological samples tested for antibodies against HIV, EBV and malaria. Odds ratios for Burkitt lymphoma were estimated using unconditional logistic regression adjusting for sex, age, and residential district. Cases had a mean age of 7.1 years and 60% were male. Cases were more likely than controls to be HIV positive (Odds ratio (OR = 12.4, 95% Confidence Interval (CI 1.3 to 116.2, p = 0.03. ORs for Burkitt lymphoma increased with increasing antibody titers against EBV (p = 0.001 and malaria (p = 0.01. Among HIV negative participants, cases were thirteen times more likely than controls to have raised levels of both EBV and malaria antibodies (OR = 13.2; 95% CI 3.8 to 46.6; p = 0.001. Reported use of mosquito nets was associated with a lower risk of Burkitt lymphoma (OR = 0.2, 95% CI, 0.03 to 0.9, p = 0.04. CONCLUSIONS: Our findings support prior evidence that EBV and malaria act jointly in the pathogenesis of Burkitt lymphoma, suggesting that malaria prevention may decrease the risk of Burkitt lymphoma. HIV may also play a role in the etiology of this childhood tumor.

  16. Objectivist case study research

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Fachner, Jörg

    2016-01-01

    be achieved through the use of objectivist case study research. The strength of the case study design is that it allows for uncovering or suggesting causal relationships in real-life settings through an intensive and rich collection of data. According to Hilliard (1993), the opposite applies for extensive......In order to comprehend the impact of music therapy or music therapy processes, a researcher might look for an approach where the topic under investigation can be understood within a broader context. This calls for a rich inclusion of data and consequently a limited number of participants and may...... designs, in which a small amount of data is gathered on a large number of subjects. With the richness of data, the intensive design is ―the primary pragmatic reason for engaging in single-case or small N research‖ (p. 374) and for working from an idiographic rather than a nomothetic perspective....

  17. The Evaluation of Thyroid Disease in the U.S.A. Resulting from Combined Exposures to Radioiodine Fallout: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Baverstock, K. [WHO Regional Office for Europe, Helsinki (Finland); Hoffman, F.O. [SENES Oak Ridge, Inc., Oak Ridge, TN (United States); Pritikin, T. [Berkeley, CA (United States)

    2001-07-01

    At the time of weapons testing in Nevada and associated activities elsewhere in mainland USA, the risks to health associated with fission product fallout were not appreciated in the way they are today. In retrospect, however, there is evidence to suggest a reluctance of the scientific community to accept the evolving evidence of harm from {sup 131}I, from the 1980s onwards. Some of this reluctance is based on extensive epidemiological follow-up of patients irradiated with diagnostic medical applications of {sup 131}I, which showed a very small effect. The epidemiological community concerned with the {sup 131}I diagnostic studies have proved to be among the most resistant to the abandonment of the belief in the reduced carcinogenic effectiveness of {sup 131}I. However, as early as 1982 Congress mandated the Department of Health and Human Services to review the doses from {sup 131}I to the public as a result of public concern for a rising incidence of thyroid disease. The Lee et al experiment was published in 1982. The conflict between the results of the Lee et al experiments and the earlier studies of the relative carcinogenicity of external radiation and {sup 131}I, led the National Cancer Inst. to take the unusual step, in the mid 1980s, of arranging an independent evaluation of the work on which the Lee paper was based. The review, the results of which were not published, endorsed the results given in the paper. Finally, the evidence of an increase in thyroid cancer after the Chernobyl accident was published in 1992. What were the factors that contributed to this resistance by the scientific community to abandoning an increasingly untenable belief? One factor could have been the use, in the US, of {sup 131}I for medical diagnostic purposes in children and reluctance to accept that this might have been damaging to health in later life. Another possibility was the recognition that, in the event of an accident to a nuclear power plant, release of radio

  18. Case Studies in Biology.

    Science.gov (United States)

    Zeakes, Samuel J.

    1989-01-01

    A case study writing exercise used in a course on parasitology was found to be a powerful learning experience for students because it involved discipline-based technical writing and terminology, brought the students in as evaluators, applied current learning, caused interaction among all students, and simulated real professional activities. (MSE)

  19. : Case studies: France

    OpenAIRE

    Bonerandi, Emmanuelle; Santamaria, Frédéric

    2005-01-01

    Case studies on territorial governance : urban region of Lyon (France) and the "Pays" policy (France) in the framework of the ESPON 2.3.2 project Études de cas sur la gouvernance territoriale : région urbaine de Lyon et politique des pays

  20. The association between component malalignment and post-operative pain following navigation-assisted total knee arthroplasty: results of a cohort/nested case-control study.

    Science.gov (United States)

    Czurda, Thomas; Fennema, Peter; Baumgartner, Martin; Ritschl, Peter

    2010-07-01

    Previous studies have noted an adverse relationship between implant malalignment during total knee arthroplasty (TKA) and post-operative pain. Although some evidence exists indicating that computer-assisted surgical navigation for TKA can improve the accuracy of component alignment, its impact on clinical outcomes is currently unknown. The dual goals of the present cohort/nested case-control study were to (1) compare self-reported responses to the Western Ontario-McMaster Osteoarthritis Index (WOMAC) questionnaire between computer-assisted TKA (123 patients) using the imageless PiGalileo navigation system and conventional TKA (207 patients) [cohort analysis], and (2) to investigate a potential association between malalignment and post-operative pain in 19 painful knees and 19 asymptomatic knees obtained from the cohort analysis using matched sampling [nested case-control study]. In the cohort analysis, a relevant but non-significant (P = 0.06) difference in the occurrence of chronic pain was observed between the navigated (12%) and conventional arms (20%). Median post-operative WOMAC pain score was 100 (range, 50-100) in the conventional group and 100 (range, 65-100) in the navigated group. However, the Mann-Whitney test revealed a significant difference in favor of the navigated group (P = 0.01). In the nested case-control analysis, radiological outcomes and computer tomography (CT) measurements of femoral rotation were compared between the groups. The CT rotation measurements yielded evidence of a relationship between post-operative pain and incorrect rotational alignment of the femoral component of more than 3 degrees (OR: 7; 95% CI: 1.2-42; P = .033). In conclusion, there was no clinical benefit to computer-assisted navigation; however, a statistically significant relationship was observed between incorrect rotational alignment of the femoral component and symptoms of post-operative pain following TKA.

  1. Improvements in dizziness and imbalance results from using a multi disciplinary and multi sensory approach to Vestibular Physical Therapy - A case study

    Directory of Open Access Journals (Sweden)

    Kim R Gottshall

    2015-08-01

    Full Text Available This paper discusses a case study of a 41 year old active duty male service member who sustained a motorcycle accident and head trauma and underwent multidisciplinary vestibular physical therapy for treatment. He was initially treated with traditional physical therapy applications of treadmill walking and standing balance with some symptom improvements, but was not able to maintain a running speed that would allow him to remain on active duty status. Further treatment utilizing a Computer Assisted Rehabilitation Environment (CAREN was performed in order to increase difficulty levels and recover more functionality. This treatment is able to elicit vestibular deficits seen in the community as it requires subjects to walk and balance while performing tasks within a virtual scenario with platform motion, visual surround and flow, and cognitive processing. After six weeks of therapy, twice weekly, improvements in clinical vestibular measures were observed as well as walking speed and patient confidence. The subject was able to return to full duty after treatment. This case study provides supportive evidence that multidimensional tasking in a virtual environment provides a safe but demanding form of vestibular therapy for patients needing more challenging tasks than those provided with traditional therapy techniques. Those persons requiring higher levels of performance before returning to work (e.g. pilots, special operators, etc. may find this type of therapy beneficial.

  2. Stapled hemorrhoidopexy: Clinical results of 65 cases

    Directory of Open Access Journals (Sweden)

    Ahmet Pergel

    2012-09-01

    Full Text Available Objectives: To present results of our patients underwentstapled hemorrhoidopexy due to hemorrhoidal diseaseand discuss in accompaniment with the literature.Material and methods: The patients, who diagnosed by3rd-4th degree hemorrhoidal disease and underwent hemorrhoidopexywith Longo method between January, 2009and April, 2011, were included. All data were prospectivelycollected and retrospectively examined. The patientswere evaluated in terms of demographic properties, complaintson admission, and postoperative complications.Results: Forty-three (66% of 65 patients were male,22 (34% were female. The mean age was 38±11.9(range:23-76 years. The most frequent complaints werebleeding, swelling, itching, pain, constipation respectively.Third degree hemorrhoid was present in fifty-eight (89%patients, 4th degree hemorrhoid was in 7 (11% patients.The mean operation duration was 37.6±8.1(range:24-55minutes, the mean hospitalization duration was 27±7.8(range:20-76 hours. One or more complication developedin total 17 (26% patients. As complication, bleedingwas determined in 13 (20% patients, pain was in 6 (9%,urinary retention was in 2 (3%, tenesmus was in 3 (5%,external hemorrhoidal thrombosis was in 1 (2%, and recurrencewas in 4 (6%.Conclusions: The patients can return their daily activitiesearly with stapled hemorrhoidopexy because of less painand quick recovery period. We consider that appropriatepatient selection and proper application of the techniqueare important in the success of this method. Particularly in3rd degree hemorrhoidal disease, Longo’s technique canbe suggested as an alternative to classical methods. JClin Exp Invest 2012; 3 (3: 340-344Key words: Hemorrhoidal disease, stapled hemorrhoidopexy,Longo’s procedure

  3. Corporate Governance. Case Studies

    OpenAIRE

    Manuel, Eduardo

    2007-01-01

    This paper pretends to do a theoretical approach of Corporate Governance, having as support some case studies about companies like Coca-Cola, Nokia, Microsoft, and Amazon.com. The methodology adopted for this work is based in information from these companies available in their websites and annual reports. I concluded that both companies show the corporate governance components according to their core business and their environmental business.

  4. Case study - Czechoslovakia

    International Nuclear Information System (INIS)

    In the lecture Case Study - Czechoslovakia with the sub-title 'Unified System of Personnel Preparation for Nuclear Programme in Czechoslovakia' the actual status and the current experience of NPP personnel training and preparation in Czechoslovakia are introduced. The above mentioned training system is presented and demonstrated by the story of a proxy person who is going to become shift engineer in a nuclear power plant in Czechoslovakia. (orig./HP)

  5. Case Studies - Cervical Cancer

    Centers for Disease Control (CDC) Podcasts

    2010-10-15

    Dr. Alan Waxman, a professor of obstetrics and gynecology at the University of New Mexico and chair of the American College of Obstetricians and Gynecologists (ACOG) committee for the underserved, talks about several case studies for cervical cancer screening and management.  Created: 10/15/2010 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Cancer Prevention and Control (DCPC).   Date Released: 6/9/2010.

  6. Sternocleidomastoid syndrome: a case study

    OpenAIRE

    Missaghi, Babak

    2004-01-01

    This article presents a case study of a patient diagnosed with dysfunction of the sternocleidomastoid (SCM) muscle, a condition which can result in head and face pain, nausea, dizziness, coryza, and lacrimation. In this particular case, the SCM muscle had developed tightness and weakness with presence of multiple trigger points within both heads. A combination of passive and active treatments were utilized to successfully treat this condition.

  7. Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis.

    Directory of Open Access Journals (Sweden)

    Marine Germain

    Full Text Available By applying an imputation strategy based on the 1000 Genomes project to two genome-wide association studies (GWAS, we detected a susceptibility locus for venous thrombosis on chromosome 11p11.2 that was missed by previous GWAS analyses that had been conducted on the same datasets. A comprehensive linkage disequilibrium and haplotype analysis of the whole locus where twelve SNPs exhibited association p-values lower than 2.23 10(-11 and the use of independent case-control samples demonstrated that the culprit variant was a rare variant located ~1 Mb away from the original hits, not tagged by current genome-wide genotyping arrays and even not well imputed in the original GWAS samples. This variant was in fact the rs1799963, also known as the FII G20210A prothrombin mutation. This work may be of major interest not only for its scientific impact but also for its methodological findings.

  8. Do qualitative methods validate choice experiment-results? A case study on the economic valuation of peatland restoration in Central Kalimantan, Indonesia

    Energy Technology Data Exchange (ETDEWEB)

    Schaafsma, M.; Van Beukering, P.J.H.; Davies, O.; Oskolokaite, I.

    2009-05-15

    This study explores the benefits of combining independent results of qualitative focus group discussions (FGD) with a quantitative choice experiment (CE) in a developing country context. The assessment addresses the compensation needed by local communities in Central Kalimantan to cooperate in peatland restoration programs by using a CE combined with a series of FGD to validate and explain the CE-results. The main conclusion of this study is that a combination of qualitative and quantitative methods is necessary to assess the economic value of ecological services in monetary terms and to better understand the underlying attitudes and motives that drive these outcomes. The FGD not only cross-validate results of the CE, but also help to interpret the differences in preferences of respondents arising from environmental awareness and ecosystem characteristics. The FGD confirms that the CE results provide accurate information for ecosystem valuation. Additional to the advantages of FGD listed in the literature, this study finds that FGD provide the possibility to identify the specific terms and conditions on which respondents will accept land-use change scenarios. The results show that FGD may help to address problems regarding the effects of distribution of costs and benefits over time that neo-classical economic theory poses for the interpretation of economic valuation results in the demand it puts on the rationality of trade-offs and the required calculations.

  9. Association between the BsmI Polymorphism in the Vitamin D Receptor Gene and Breast Cancer Risk: Results from a Pakistani Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Muhammad Usman Rashid

    Full Text Available Vitamin D is postulated to decrease the risk of breast cancer by inhibiting cell proliferation via the vitamin D receptor (VDR. Two common single nucleotide polymorphisms (SNPs in the VDR gene, rs1544410 (BsmI and rs2228570 (FokI, are inconsistently associated with breast cancer risk in Caucasian populations, while data for Asians are scarce. Here, we investigated the possible contribution of these SNPs to breast cancer risk in Pakistani breast cancer patients and in controls participating in a hospital-based breast cancer case-control study (PAK-BCCC.Genotyping of the BsmI and FokI SNPs was performed by PCR-based restriction fragment length polymorphism (RFLP analysis of 463 genetically enriched female breast cancer cases with known BRCA1/2 status and in 1,012 controls from Pakistan. The association between SNP genotypes and breast cancer risk was investigated by logistic regression adjusted for potential breast cancer risk factors and stratified by BRCA1/2 status and family history. Odds ratios (ORs and 95% confidence intervals (CIs were reported.The b allele of the BsmI was associated with an increased breast cancer risk (per b allele OR 1.28, 95% CI 1.09-1.49, P = 0.003. Subgroup analysis revealed that this effect was restricted to BRCA1/2 non-carriers (per b allele OR 1.33, 95% CI 1.11-1.59, P = 0.002 and was stronger in those who reported a positive family history of breast and/or ovarian cancer (per b allele OR 1.64, 95% CI 1.20-2.22, P = 0.002. No association with breast cancer risk was detected for the FokI SNP.The BsmI polymorphism in the VDR gene may be associated with an increased breast cancer risk in Pakistani women negative for BRCA1/2 germline mutations.

  10. RESULTS OF SUPPLEMENTAL MST STUDIES

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T; David Hobbs, D; Samuel Fink, S

    2006-07-24

    The current design of the Salt Waste Processing Facility (SWPF) includes an auxiliary facility, the Actinide Finishing Facility, which provides a second contact of monosodium titanate (MST) to remove soluble actinides and strontium from waste if needed. This treatment will occur after cesium removal by Caustic-Side Solvent Extraction (CSSX). Although the process changes and safety basis implications have not yet been analyzed, provisions also exist to recover the MST from this operation and return to the initial actinide removal step in the SWPF for an additional (third) contact with fresh waste. A U.S. Department of Energy (DOE) request identified the need to study the following issues involving this application of MST: Determine the effect of organics from the solvent extraction (CSSX) process on radionuclide sorption by MST; Determine the efficiency of re-using MST for multiple contacts; and Examine fissile loading on MST under conditions using a waste containing significantly elevated concentrations of plutonium, uranium, neptunium, and strontium. This report describes the results of three experimental studies conducted to address these needs: (1) Addition of high concentrations of entrained CSSX solvent had no noticeable effect, over a two week period, on the sorption of the actinides and strontium by MST in a direct comparison experiment. (2) Test results show that MST still retains appreciable capacity after being used once. For instance, reused MST--in the presence of entrained solvent--continued to sorb actinides and strontium. (3) A single batch of MST was used to sequentially contact five volumes of a simulant solution containing elevated concentrations of the radionuclides of interest. After the five contacts, we measured the following solution actinide loadings on the MST: plutonium: 0.884 {+-} 0.00539 wt % or (1.02 {+-} 0.0112) E+04 {micro}g/g MST, uranium: 12.1 {+-} 0.786 wt % or (1.40 {+-} 0.104) E+05 {micro}g/g MST, and neptunium: 0.426 {+-} 0

  11. Mitigating the cooling need and improvement of indoor conditions in Mediterranean educational buildings, by means of green roofs. Results of a case study

    Science.gov (United States)

    Ascione, F.; Bianco, N.; De Masi, R. F.; de Rossi, F.; Vanoli, G. P.

    2015-11-01

    Indoor overheating risk and increased energy demand for cooling are becoming more and more frequent in the building sector of the Mediterranean area. In detail, for the reduction of the energy consumption of educational buildings, characterized by high endogenous gains, the particular boundary conditions affecting their use should be taken in consideration, and thus schedules of occupancy, wide necessity of air-changes for air quality. This paper, with reference to a case study, proposes deep investigations aimed at optimizing the annual energy performance of an educational building of the University of Sannio, located in the Southern Italy. A numerical model of the building has been designed and validated according to monitored data. Starting from the present scenario, after a complete refurbishment of the building envelope, the potentialities of several typologies of green roofs - by considering also the implementation of the adaptive approach in the comfort standard - have been tested. The scope is the optimization of the energy demand for the annual microclimatic control, by avoiding an energy-intensive operation of the air-conditioning devices during the warm season.

  12. A case study in the New York Drumlin Field, an investigation using microsedimentology, resulting in the refinement of a theory of drumlin formation

    Science.gov (United States)

    Menzies, John; Hess, Dale P.; Rice, Jessey M.; Wagner, Kaleb G.; Ravier, Edouard

    2016-06-01

    The formation of drumlins remains a major enigma. It is accepted that drumlins form under active temperate ice most likely within a soft sediment deforming bed at ephemeral 'sticky points'. These 'sticky points' likely lead to the causative mechanism around which sediment nucleation occurs. The critical question is under what conditions and where and how do 'sticky spots' form. A comparative investigation of a drumlin and mega-flute in the New York Drumlin Field, as a case study, demonstrates that rheological and sedimentological tills from these different forms are similar. It is not, therefore, rheological change alone that must account for drumlin shape and form but likely the advective subglacial basal sediment flux rate at the ice bed. The rate of sediment motion between the upper interface at the ice-sediment bed boundary, and the lower immobile sediment at depth is crucial. At the lower décollement between the mobile and immobile sediment units, within the deforming sediment package, proto-drumlin nucleation is likely to occur and develop into a streamlined form. The trigger mechanism for such a perturbation is a derivative of sediment rheology and sediment flux rate driven by the overlying ice stresses. Recent evidence from Antarctica lends credence to this new hypothesis that can be related to all drumlins formed under temperate, soft sediment deforming bed conditions.

  13. Risk factors for extrahepatic biliary tract carcinoma in men: medical conditions and lifestyle: results from a European multicentre case-control study

    DEFF Research Database (Denmark)

    Ahrens, Wolfgang; Timmer, Antje; Vyberg, Mogens;

    2007-01-01

    or smoking showed no clear association, whereas some increase in risk was suggested for consumption of 40-80 g alcohol per day and more. CONCLUSIONS: Our study corroborates gallstones as a risk indicator in extrahepatic biliary tract carcinoma. Permanent overweight and obesity in adult life was identified...... as a strong risk factor for extrahepatic biliary tract carcinoma, whereas we did not find any strong lifestyle-associated risk factors. Inconsistent results across studies concerning the association of extrahepatic biliary tract carcinoma with overweight and obesity may be explained by the different......-matched by age and region. Adjusted odds ratios and 95%-confidence intervals were estimated by logistic regression. RESULTS: The analysis included 153 patients and 1421 controls. The participation proportion was 71% for patients and 61% for controls. Gallstone disease was corroborated as a risk factor...

  14. Oral contraceptives and cancers of the breast and of the female genital tract. Interim results from a case-control study.

    OpenAIRE

    La Vecchia, C; Decarli, A; Fasoli, M.; Franceschi, S.; Gentile, A.; Negri, E; Parazzini, F.; Tognoni, G

    1986-01-01

    We analysed data from a case-control investigation conducted in Milan, Northern Italy, to evaluate the relation between the use of combination oral contraceptives and the risk of cancers of the breast, ovary, endometrium and cervix uteri. For the present analysis, 776 cases of histologically confirmed breast cancer, 406 of epithelial ovarian cancer and 170 of endometrial cancer aged under 60 were compared with a group of 1,282 subjects below age 60 admitted for a spectrum of acute conditions ...

  15. Vertebral Angiosarcoma. Case Study.

    Science.gov (United States)

    Guzik, Grzegorz

    2015-01-01

    Bone angiosarcomas, especially vertebral angiosarcomas, are very rare. There are no studies based on large clinical samples in the literature, and only a few single case reports can be found. The symptoms of the disease are not specific. It is usually detected incidentally or at a late stage when pathological vertebral fractures or neurological complications occur. Diagnostic imaging and history help to recognize the tumour behind the symptoms, but do not allow accurate clinical diagnosis. The basis for a diagnosis is the histopathological examination supported by immunohistochemistry (IHC) assays. The case of a 26-year-old woman with an angiosarcoma involving the eighth thoracic vertebra we report reflects diagnostic problems adversely affecting the efficacy and accuracy of treatment offered to patients. The patient underwent three surgeries of the spine, including two biopsies. A needle biopsy did not provide sufficient information for the diagnosis. An open excisional biopsy, which at the same time temporarily reduced neurological deficits in the patient, was the only chance to obtain an accurate diagnosis. The third surgery was posterior decompression of the spinal cord due to the rapidly escalating paraparesis. It was not until 8 weeks later that the final diagnosis was established. At that time, the patient could not be qualified for any supplementary treatment. The patient died in hospital 6 months after the onset of disease. PMID:26468177

  16. The FAST-T approach for operational, real time, short term hydrological forecasting: Results from the Betania Hydropower Reservoir case study

    Science.gov (United States)

    Domínguez, Efraín; Angarita, Hector; Rosmann, Thomas; Mendez, Zulma; Angulo, Gustavo

    2013-04-01

    A viable quantitative hydrological forecasting service is a combination of technological elements, personnel and knowledge, working together to establish a stable operational cycle of forecasts emission, dissemination and assimilation; hence, the process for establishing such system usually requires significant resources and time to reach an adequate development and integration in order to produce forecasts with acceptable levels of performance. Here are presented the results of this process for the recently implemented Operational Forecast Service for the Betania's Hydropower Reservoir - or SPHEB, located at the Upper-Magdalena River Basin (Colombia). The current scope of the SPHEB includes forecasting of water levels and discharge for the three main streams affluent to the reservoir, for lead times between +1 to +57 hours, and +1 to +10 days. The core of the SPHEB is the Flexible, Adaptive, Simple and Transient Time forecasting approach, namely FAST-T. This comprises of a set of data structures, mathematical kernel, distributed computing and network infrastructure designed to provide seamless real-time operational forecast and automatic model adjustment in case of failures in data transmission or assimilation. Among FAST-T main features are: an autonomous evaluation and detection of the most relevant information for the later configuration of forecasting models; an adaptively linearized mathematical kernel, the optimal adaptive linear combination or OALC, which provides a computationally simple and efficient algorithm for real-time applications; and finally, a meta-model catalog, containing prioritized forecast models at given stream conditions. The SPHEB is at present feed by the fraction of hydrological monitoring network installed at the basin that has telemetric capabilities via NOAA-GOES satellites (8 stages, approximately 47%) with data availability of about a 90% at one hour intervals. However, there is a dense network of 'conventional' hydro

  17. Results of a prospective study

    OpenAIRE

    Weblus, Anna Julka

    2010-01-01

    Listening to music can influence body and mind. But whether aspects of quality of life during the beginning of a systemic cytostatic chemotherapy of women with gynecologic malignancies can be influenced by listening to Mozart or relaxation music is being investigated in this study for the first time. For this purpose 61 women with a malignant tumor of the breast, the ovaries, the cervix, the endometrium or the tubes, in need of a cytostatic chemotherapy, have been investigated during the firs...

  18. Skylab experiment results: Hematology studies

    Science.gov (United States)

    Kimzey, S. L.; Ritzmann, S. E.; Mengel, C. E.; Fischer, C. L.

    1975-01-01

    Studies were conducted to evaluate specific aspects of man's immunologic and hematologic systems that might be altered by or respond to the space flight environment. Biochemical functions investigated included cytogenetic damage to blood cells, immune resistance to disease, regulation of plasma and red cell volumes, metabolic processes of the red blood cell, and physicochemical aspects of red blood cell function. Measurements of hematocrit value showed significant fluctuations postflight, reflecting observed changes in red cell mass and plasma volume. The capacity of lymphocytes to respond to an in vitro mitogenic challenge was repressed postflight, and appeared to be related to mission duration. Most other deviations from earth function in these systems were minor or transient.

  19. Examples and Case Studies

    NARCIS (Netherlands)

    Asbach, C.; Aguerre, O.; Bressot, C.; Brouwer, D.H.; Gommel, U.; Gorbunov, B.; Bihan, O. le; Jensen, K.A.; Kaminski, H.; Keller, M.; Koponen, I.K.; Kuhlbusch, T.A.J.; Lecloux, A.; Morgeneyer, M.; Muir, R.; Shandilya, N.; Stahlmecke, B.; Todea, A.M.

    2014-01-01

    Release of nanomaterials may occur during any stage of the life-cycle and can eventually lead to exposure to humans, the environment or products. Due to the large number of combinations of release processes and nanomaterials, release scenarios can currently only be tested on a case-by-case basis. Th

  20. Termination: A Case Study.

    Science.gov (United States)

    Friedberg, Ahron L

    2015-12-01

    In this article I posit and examine certain criteria and qualities for ending an analysis. The case study describes the end phase of a four-year psychoanalysis in which the patient's decision to move to another area forced the end of his analysis. We continued to explore and work through his core neurotic conflicts that included issues of competitive rivalry, dominance and submission, control, and anxiety about birth and death. A shift in the transference from me as a negative father to me as a supportive but competitive older brother was also examined in the context of ending treatment as well as other aspects of the transference. In addition, we analyzed the meaning of his ending treatment based on an extra-analytic circumstance. In discussing this phase of treatment, the definition and history of the term "termination" and its connotations are reviewed. Various criteria for completing an analysis are examined, and technical observations about this phase of treatment are investigated. It was found that while a significant shift in the transference occurred in this phase of the patient's analysis, conflicts related to the transference were not "resolved" in the classical sense. Terminating treatment was considered as a practical matter in which the patient's autonomy and sense of choice were respected and analyzed. PMID:26583444

  1. Normalisation method can affect gluteus medius electromyography results during weight bearing exercises in people with hip osteoarthritis (OA): a case control study.

    Science.gov (United States)

    French, Helen P; Huang, Xiaoli; Cummiskey, Andrew; Meldrum, Dara; Malone, Ailish

    2015-02-01

    Surface electromyography (sEMG) is used to assess muscle activation during therapeutic exercise, but data are significantly affected by inter-individual variability and requires normalisation of the sEMG signal to enable comparison between individuals. The purpose of this study was to compare two normalisation methods, a maximal method (maximum voluntary isometric contraction (MVIC)) and non-maximal peak dynamic method (PDM), on gluteus medius (GMed) activation using sEMG during three weight-bearing exercises in people with hip osteoarthritis (OA) and healthy controls. Thirteen people with hip OA and 20 controls performed three exercises (Squat, Step-Up, Step-Down). Average root-mean squared EMG amplitude based on MVIC and PDM normalisation was compared between groups for both involved and uninvolved hips using Mann-Whitney tests. Using MVIC normalisation, significantly higher normalised GMed EMG amplitudes were found in the OA group during all Step-up and down exercises on the involved side (p=0.02-0.001) and most of the Step exercises on the uninvolved side (p=0.03-0.04), but not the Squat (p>0.05), compared to controls. Using PDM normalisation, significant between-group differences occurred only for Ascending Squat (p=0.03) on the involved side. MVIC normalisation demonstrated higher inter-trial relative reliability (ICCs=0.78-0.99) than PDM (ICCs=0.37-0.84), but poorer absolute reliability using Standard Error of Measurement. Normalisation method can significantly affect interpretation of EMG amplitudes. Although MVIC-normalised amplitudes were more sensitive to differences between groups, there was greater variability using this method, which raises concerns regarding validity. Interpretation of EMG data is strongly influenced by the normalisation method used, and this should be considered when applying EMG results to clinical populations.

  2. A coupled model approach to reduce nonpoint-source pollution resulting from predicted urban growth: A case study in the Ambos Nogales watershed

    Science.gov (United States)

    Norman, L.M.; Guertin, D.P.; Feller, M.

    2008-01-01

    The development of new approaches for understanding processes of urban development and their environmental effects, as well as strategies for sustainable management, is essential in expanding metropolitan areas. This study illustrates the potential of linking urban growth and watershed models to identify problem areas and support long-term watershed planning. Sediment is a primary source of nonpoint-source pollution in surface waters. In urban areas, sediment is intermingled with other surface debris in transport. In an effort to forecast the effects of development on surface-water quality, changes predicted in urban areas by the SLEUTH urban growth model were applied in the context of erosion-sedimentation models (Universal Soil Loss Equation and Spatially Explicit Delivery Models). The models are used to simulate the effect of excluding hot-spot areas of erosion and sedimentation from future urban growth and to predict the impacts of alternative erosion-control scenarios. Ambos Nogales, meaning 'both Nogaleses,' is a name commonly used for the twin border cities of Nogales, Arizona and Nogales, Sonora, Mexico. The Ambos Nogales watershed has experienced a decrease in water quality as a result of urban development in the twin-city area. Population growth rates in Ambos Nogales are high and the resources set in place to accommodate the rapid population influx will soon become overburdened. Because of its remote location and binational governance, monitoring and planning across the border is compromised. One scenario described in this research portrays an improvement in water quality through the identification of high-risk areas using models that simulate their protection from development and replanting with native grasses, while permitting the predicted and inevitable growth elsewhere. This is meant to add to the body of knowledge about forecasting the impact potential of urbanization on sediment delivery to streams for sustainable development, which can be

  3. Impact of recent Global Digital Bathymetry and Topography Models on geoid modelling: Results from two case studies in Balearic and Aegean Seas

    Science.gov (United States)

    Delikaraoglou, D.; Mintourakis, I.; Kallianou, F.

    2009-04-01

    With the realization of the Shuttle Radar Topographic Mission (SRTM) and the free distribution of its global elevation dataset with 3 arcsec (90 m) resolution and less than 16 m vertical accuracy, together with the availability of the higher resolution (30 m) and accuracy (10 m) Digital Terrain Models (DTM) from the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), these two valuable sources of uniform DEM data represent a revolution in the world of terrain modelling. DEMs are an important source of data for the generation of high resolution geoids since they provide the high-frequency content of the gravity field spectrum and are suitable for the computation of terrain effects to gravity and indirect effects to the geoid, thus allowing the combination of global geopotential models, local gravity anomalies and information about the earth's topography (represented by a given DEM). However, although such models are available for land, there are no readily accessible Digital Bathymetry Models (DBMs) of equivalent quality for the coastal and oceanic regions. Most of the global DBM's (e.g. ETOPO1, SRTM30, and GEBCO global bathymetric grid) are compilations of heterogeneous data with medium resolution and accuracy. This prevents to exploit the potential of the recent high resolution (1 arcmin) marine free-air gravity anomalies datasets derived from satellite altimetry (such as the DNSC08, and the Sandwell & Smith v18.1 (S&Sv18.1) global solutions) in conjunction with such global DBM's. Fortunately, for some regions, recently have become available DBM's of much better accuracy and resolution, such as the DBM of 1 km resolution for many regions of the Mediterranean Sea which is distributed by IFREMER, the French Research Institute for Exploitation of the Sea. The scope of this study is to use this latest regional DBM in combination with the newly available DNSC08 and SSV18.1 global marine free-air gravity anomalies datasets for marine and near shore

  4. Gender differences and temporal variation in the incidence of type 1 diabetes : results of 8012 cases in the nationwide Diabetes Incidence Study in Sweden 1983-2002

    NARCIS (Netherlands)

    Ostman, J.; Lonnberg, G.; Arnqvist, H. J.; Blohme, G.; Bolinder, J.; Schnell, A. Ekbom; Eriksson, J. W.; Gudbjornsdottir, S.; Sundkvist, G.; Nystrom, L.

    2008-01-01

    Objectives. To establish the gender difference amongst newly diagnosed type 1 diabetic patients aged 15-34 years, considering age at diagnosis, temporal trend and seasonal variation at time of diagnosis. Study design. A population-based prospective study with a mean annual population at risk of 2.3

  5. Quantitatively Verifying the Results' Rationality for Farmland Quality Evaluation with Crop Yield, a Case Study in the Northwest Henan Province, China.

    Science.gov (United States)

    Zhang, Yali; Huang, Junchang; Yu, Lin; Wang, Song

    2016-01-01

    Evaluating the assessing results' rationality for farmland quality (FQ) is usually qualitative and based on farmers and experts' perceptions of soil quality and crop yield. Its quantitative checking still remains difficult and is likely ignored. In this paper, FQ in Xiuwu County, the Northwest Henan Province, China was evaluated by the gray relational analysis (GRA) method and the traditional analytic hierarchy process (AHP) method. The consistency rate of two results was analysed. Research focused on proposing one method of testing the evaluation results' rationality for FQ based on the crop yield. Firstly generating a grade map of crop yield and overlying it with the FQ evaluation maps. Then analysing their consistency rate for each grade in the same spatial position. Finally examining the consistency effects and allowing for a decision on adopting the results. The results showed that the area rate consistency and matching evaluation unit numbers between the two methods were 84.68% and 87.29%, respectively, and the space distribution was approximately equal. The area consistency rates between crop yield level and FQ evaluation levels by GRA and AHP were 78.15% and 74.29%, respectively. Therefore, the verifying effects of GRA and AHP were near, good and acceptable, and the FQ results from both could reflect the crop yield levels. The evaluation results by GCA, as a whole, were slightly more rational than that by AHP. PMID:27490247

  6. Hydraulic fracture model comparison study: Complete results

    Energy Technology Data Exchange (ETDEWEB)

    Warpinski, N.R. [Sandia National Labs., Albuquerque, NM (United States); Abou-Sayed, I.S. [Mobil Exploration and Production Services (United States); Moschovidis, Z. [Amoco Production Co. (US); Parker, C. [CONOCO (US)

    1993-02-01

    Large quantities of natural gas exist in low permeability reservoirs throughout the US. Characteristics of these reservoirs, however, make production difficult and often economic and stimulation is required. Because of the diversity of application, hydraulic fracture design models must be able to account for widely varying rock properties, reservoir properties, in situ stresses, fracturing fluids, and proppant loads. As a result, fracture simulation has emerged as a highly complex endeavor that must be able to describe many different physical processes. The objective of this study was to develop a comparative study of hydraulic-fracture simulators in order to provide stimulation engineers with the necessary information to make rational decisions on the type of models most suited for their needs. This report compares the fracture modeling results of twelve different simulators, some of them run in different modes for eight separate design cases. Comparisons of length, width, height, net pressure, maximum width at the wellbore, average width at the wellbore, and average width in the fracture have been made, both for the final geometry and as a function of time. For the models in this study, differences in fracture length, height and width are often greater than a factor of two. In addition, several comparisons of the same model with different options show a large variability in model output depending upon the options chosen. Two comparisons were made of the same model run by different companies; in both cases the agreement was good. 41 refs., 54 figs., 83 tabs.

  7. Teaching Pharmacology by Case Study.

    Science.gov (United States)

    Jordan, Sue

    1997-01-01

    Using pharmacology case studies with nursing students encourages theory-practice links and infuses real-life content. Cases provide rich qualitative data for evaluating curriculum. However, they are not a substitute for evidence-based practice. (SK)

  8. Recognition of anxiety disorders by family physicians after rigorous medical record case extraction: results of the Netherlands Study of Depression and Anxiety.

    NARCIS (Netherlands)

    Janssen, E.H.C.; Ven, P.M. van de; Terluin, B.; Verhaak, P.F.M.; Marwijk, H.W.J. van; Smolders, M.; Meer, K. van der; Penninx, B.W.J.H.; Hout, H.P.J. van

    2012-01-01

    Objective: Previous studies reported low and inconsistent rates of recognition of anxiety disorders by family physicians (FPs). Our objectives were to examine (a) which combination of indications within medical records most accurately reflects recognition of anxiety disorders and (b) whether patient

  9. Recognition of anxiety disorders by family physicians after rigorous medical record case extraction Results of the Netherlands Study of Depression and Anxiety

    NARCIS (Netherlands)

    Janssen, Evelien H. C.; van de Ven, Peter M.; Terluin, Berend; Verhaak, Peter F. M.; van Marwijk, Harm W. J.; Smolders, Mirrian; van der Meer, Klaas; Penninx, Brenda W. J. H.; van Hout, Hein P. J.

    2012-01-01

    Objective: Previous studies reported low and inconsistent rates of recognition of anxiety disorders by family physicians (FPs). Our objectives were to examine (a) which combination of indications within medical records most accurately reflects recognition of anxiety disorders and (b) whether patient

  10. Clot lysis time and the risk of myocardial infarction and ischaemic stroke in young women; results from the RATIO case-control study

    NARCIS (Netherlands)

    Siegerink, Bob; Meltzer, Mirjam E.; de Groot, Philip G.; Algra, Ale; Lisman, Ton; Rosendaal, Frits R.

    2012-01-01

    Reduced overall fibrinolytic capacity increases the risk of myocardial infarction (MI), as demonstrated in studies with predominantly male participants. We determined the influence of altered fibrinolysis on the risk of MI and ischaemic stroke (IS) in young women. The RATIO (Risk of Arterial Thrombo

  11. Intercultural Communicative Case Study

    Institute of Scientific and Technical Information of China (English)

    吴冬梅

    2009-01-01

    The essay is mainly about the author's comprehension of cultural differences and intercultural communication after reading the book Communication Between Cultures.In addition,the author also analyses three cases with the theories and approaches mentioned in Communication Between Cultures.

  12. Factors affecting Navy Working Capital Fund (NWCF) net operating result: a case study of Naval Facilities Engineering Command Washington, Washington D.C.

    OpenAIRE

    Duong, Tamanh Q.; Uribe, Juan C.; Johnson, Greg R.

    2009-01-01

    Over the past four years, Naval Facilities Engineering Command (NAVFAC) Washington has encountered net operating result (NOR) losses not anticipated in the Navy Working Capital Fund (NWCF) budget. These unanticipated losses primarily stemmed from three major factors associated with financial operations. The first factor is the creation of stabilized rates that turned out to be insufficient during fiscal years 2006, 2007 and 2008. The second factor is the disparity between the budgeted and...

  13. Simulation of Groundwater Mound Resulting from Proposed Artificial Recharge of Treated Sewage Effluent Case study – Gaza waste water treatment plant, Palestine

    OpenAIRE

    Aish, Adnan Mousa

    2010-01-01

    Mounding of the groundwater table beneath recharge sources is of concern as the raised water table approaches closely to near-surface facilities or features. The shape and height of the mound depend on several factors including the recharge rate, hydraulic conductivity and thickness of the aquifer. The objective of this paper is to evaluate the suitability of the study area for a rapid infiltration system of treated wastewater effluent without causing excessive mounding of the water table. A ...

  14. Sustainable gasification–biochar systems? A case-study of rice-husk gasification in Cambodia, Part II: Field trial results, carbon abatement, economic assessment and conclusions

    International Nuclear Information System (INIS)

    In part I we described the gasification technology and characterised the physio-chemical properties and environmental impacts of the rice husk char (RHC) by-product. In part II we present summary results from field trials using the RHC, and provide an estimate of the carbon abatement and economic evaluation of the system. Statistically significant yield increases are demonstrated for RHC addition in irrigated rice cultivation (33% increase in paddy rice yield for a 41.5 t (dry weight) RHC application per hectare). The carbon abatement from the RHC addition is approximately 0.42 t CO2 t−1 rice husk; including energy generation from gasification this increases to ca. 0.86 tCO2 t−1. Assuming a carbon value of $5 t CO2 t−1, and agronomic value of $3 t−1 RHC based on the field trials, the economic value of the RHC varies from $9 t−1 (including only recalcitrant carbon) to $15 t−1 (including avoided emissions from energy production). We summarise results from parts I and II, concluding that the gasification–biochar system meets many of the criteria of sustainability, but requires better waste water management and more field trials to demonstrate repeatable agronomic efficacy of RHC application. - Highlights: ► Field trials show statistically significant rice yield increases using rice husk char (RHC). ► Carbon abatement of 0.42 t CO2 t−1 rice husk from RHC production. ► Bioenergy generation via gasification gives carbon abatement of 0.44 t CO2 t−1 husk. ► Total carbon abatement is therefore ca. 0.86 t CO2 t−1 husk. ► Agronomic value from trials is $3 t−1 char; assuming $5 CO2 t−1, the total value of RHC is $9–$15 t−1.

  15. Case Study - "Marketing Christmas"

    Institute of Scientific and Technical Information of China (English)

    何青青

    2011-01-01

    @@ The following is based on a real case but the name of the company has been changed and the source will only be revealed after the submission deadline.It is June in Eastern China and temperatures are over 30 degrees Celsius.In Huang Yi-Ju's wholesale showroom, based in Yiwu, model Father Christmases line the shelves, fill the floors and scale the walls.

  16. Results of analysis of archive MSG data in the context of MCS prediction system development for economic decisions assistance - case studies

    Science.gov (United States)

    Szafranek, K.; Jakubiak, B.; Lech, R.; Tomczuk, M.

    2012-04-01

    PROZA (Operational decision-making based on atmospheric conditions) is the project co-financed by the European Union through the European Regional Development Fund. One of its tasks is to develop the operational forecast system, which is supposed to support different economies branches like forestry or fruit farming by reducing the risk of economic decisions with taking into consideration weather conditions. In the frame of this studies system of sudden convective phenomena (storms or tornados) prediction is going to be built. The main authors' purpose is to predict MCSs (Mezoscale Convective Systems) basing on MSG (Meteosat Second Generation) real-time data. Until now several tests were performed. The Meteosat satellite images in selected spectral channels collected for Central Europe Region for May and August 2010 were used to detect and track cloud systems related to MCSs. In proposed tracking method first the cloud objects are defined using the temperature threshold and next the selected cells are tracked using principle of overlapping position on consecutive images. The main benefit to use a temperature thresholding to define cells is its simplicity. During the tracking process the algorithm links the cells of the image at time t to the one of the following image at time t+dt that correspond to the same cloud system (Morel-Senesi algorithm). An automated detection and elimination of some instabilities presented in tracking algorithm was developed. The poster presents analysis of exemplary MCSs in the context of near real-time prediction system development.

  17. Radioactive contamination of the environment as a result of uranium production: a case study at the abandoned Lincang uranium mine, Yunnan Province, China

    Institute of Scientific and Technical Information of China (English)

    徐乐昌; 王焰新; 吕俊文; 卢学实; 刘耀驰; 刘晓阳

    2002-01-01

    The distribution of radioactive pollutants, such as 222Rn, U, Th and 226Ra in the air, surface waters, soils and crops around the Lincang uranium mine, Yunnan Province, China, is studied. The mechanical, geochemical and biogeochemical processes responsible for the transport and fate of the radioactive elements are discussed based on the monitoring data. The pollutants concentrations of effluents from the mine tunnels were dependent on pH and which were controlled by biochemical oxidation of sulfide in the ore/host rocks. Radon anomalies in air reached 4 km from the tailings pile depending on radon release from the site, topography and climate. 238U and 226Ra abnormities in stream sediments and soil were 40-90 cm deep and 790-800 m away downstream. Anomalies of radioactive contaminants of surface watercourses extended 7.5-13 km from the discharge of effluents of the site mainly depending on mechanical and chemical processes. There were about 2.86 ha rice fields and 1.59 km stream sediments contaminated. Erosion of tailings and mining debris with little or no containment or control accelerated the contamination processes.

  18. Study on Case Teaching of Financial Management

    Science.gov (United States)

    Che, Zhenghong; Che, Zhengmei

    2011-01-01

    Case teaching is an efficient teaching method of management. It plays an important role to enhance the students' ability to practice the theory. However, case teaching of financial management has not achieved the expected results. The paper aims to study the importance, characteristics and corresponding methods of case teaching method of financial…

  19. Radioactive contamination of the environment as a result of uranium production: a case study at the abandoned Lincang uranium mine, Yunnan Province, China

    Institute of Scientific and Technical Information of China (English)

    XU; Lechang(

    2002-01-01

    [1]Gillmore, G. K., Grattan, J., Pyatt, F. B. et al., Radon, water and abandoned metalliferous mines in the UK: Environmental and Human Health Implications, in Uranium in the Aquatic Environment, Proceedings of the International Conference Uranium Mining and Hydrogeology III and the International Mine Water Association Symposium (eds. Merkel, B. J., Planer-Friedrich, B., Wolkersdorfer, C.), Berlin: Springer, 2002, 65-76.[2]GB/T 16146-1995, Standards for Controlling Radon Concentration in Dwellings (in Chinese).[3]Kinze, M., Dose limits and maximum concentration limits (MCL's) for radionuclides--Implication on remediation of uranium mining and milling facilities in Saxony Germany, in Uranium in the Aquatic Environment, Proceedings of the International Conference Uranium Mining and Hydrogeology III and the International Mine Water Association Symposium (eds. Merkel, B. J., Planer-Friedrich, B., Wolkersdorfer, C.), Berlin: Springer, 2002, 1-7.[4]Xu, L. C., Wang, Y. X., Environmental issues and remedial actions of the abandoned Lincang uranium mine in China, in Uranium in the Aquatic Environment, Proceedings of the International Conference Uranium Mining and Hydrogeology III and the International Mine Water Association Symposium (eds. Merkel, B. J., Planer-Friedrich, B., Wolkersdorfer, C.), Berlin: Springer, 2002, 709-718.[5]International Atomic Energy Agency, Decommissioning of Facilities for Mining and Milling of Radioactive Ores and Closeout of Residues, Technical Report Series No. 362, Vienna: IAEA, 1994, 70.[6]OECD/NEA (Nuclear Energy Agency), Environment Activities in Uranium Mining and Milling, A Joint NEA/IAEA Report, Paris: Pubie en Francais Sous le Titre, 1999, 23-26.[7]Xu, L. C., Dai, X., Tan, T. et al., Environment Impact Report on Environmental Treatment Engineering of Decommissioning Lincang Uranium Mine (Feasibility studies stages) ( in Chinese), 1999.[8]Zhang Zhihui, Measurement Methods of Radon and Its Daughters in

  20. Case Study: Case Studies and the Flipped Classroom

    Science.gov (United States)

    Herreid, Clyde Freeman; Schiller, Nancy A.

    2013-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses the positive and negative aspects of the "flipped classroom." In the flipped classroom model, what is normally done in class and what is normally done as…

  1. Building theories from case study research: the progressive case study

    NARCIS (Netherlands)

    Steenhuis, Harm-Jan; Bruijn, de Erik J.

    2006-01-01

    Meredith (1998) argues for more case and field research studies in the field of operations management. Based on a literature review, we discuss several existing approaches to case studies and their characteristics. These approaches include; the Grounded Theory approach which proposes no prior litera

  2. Theory Testing Using Case Studies

    DEFF Research Database (Denmark)

    Møller, Ann-Kristina Løkke; Dissing Sørensen, Pernille

    2014-01-01

    testing using case studies, including the associated research goal, analysis, and generalisability. We argue that research designs for theory testing using case studies differ from theorybuilding case study research designs because different research projects serve different purposes and follow different......The appropriateness of case studies as a tool for theory testing is still a controversial issue, and discussions about the weaknesses of such research designs have previously taken precedence over those about its strengths. The purpose of the paper is to examine and revive the approach of theory...... research paths....

  3. Can the management of blood sugar levels in gestational diabetes mellitus cases be an indicator of maternal and fetal outcomes? The results of a prospective cohort study from India

    Directory of Open Access Journals (Sweden)

    Rajesh Jain

    2016-01-01

    Full Text Available Background: Gestational diabetes mellitus (GDM is emerging as an important public health problem in India owing to its increasing prevalence since the last decade. The issue addressed in the study was whether the management of blood sugar levels in GDM cases can predict maternal and fetal outcomes. Materials and Methods: A prospective cohort study was done for 1 year from October 1, 2013, to September 31, 2014, at 652 diabetic screening units as a part of the Gestational Diabetes Prevention and Control Project approved by the Indian Government in the district of Kanpur, state of Uttar Pradesh. A total of 57,108 pregnant women were screened during their 24–28th weeks of pregnancy by impaired oral glucose test. All types of maternal and perinatal outcomes were followed up in both GDM and non-GDM categories in the 2nd year (2013–2014 after blood sugar levels were controlled. Results: It was seen that for all kinds of maternal and fetal outcomes, the differences between GDM cases and non-GDM cases were highly significant (P 1 in every case. Moreover, perinatal mortality also increased significantly from 5.7% to 8.9% when blood sugar levels increased from 199 mg/dl and above. Perinatal and maternal outcomes in GDM cases were also significantly related to the control of blood sugar levels (P < 0.0001. Conclusion: Blood sugar levels can be an indicator of maternal and perinatal morbidity and mortality in GDM cases, provided unified diagnostic criteria are used by Indian laboratories. However, to get an accurate picture on this issue, all factors need further study.

  4. Theory testing using case studies

    DEFF Research Database (Denmark)

    Dissing Sørensen, Pernille; Løkke Nielsen, Ann-Kristina

    Case studies may have different research goals. One such goal is the testing of small-scale and middle-range theories. Theory testing refers to the critical examination, observation, and evaluation of the 'why' and 'how' of a specified phenomenon in a particular setting. In this paper, we focus...... on the strengths of theory-testing case studies. We specify research paths associated with theory testing in case studies and present a coherent argument for the logic of theoretical development and refinement using case studies. We emphasize different uses of rival explanations and their implications for research...... design. Finally, we discuss the epistemological logic, i.e., the value to larger research programmes, of such studies and, following Lakatos, conclude that the value of theory-testing case studies lies beyond naïve falsification and in their contribution to developing research programmes in a progressive...

  5. Three Community College Case Studies

    Science.gov (United States)

    Wojtysiak, Joseph; Sutton, William J., II; Wright, Tommy; Brantley, Linda

    2011-01-01

    This article presents three case studies that focus on specific projects that are underway or have been completed. In the first case study, Joseph Wojtysiak and William J. Sutton, II discuss the Green Center of Central Pennsylvania, which is designed to serve as the state's preeminent source for education, training and public information about…

  6. The European I-MOVE Multicentre 2013-2014 Case-Control Study. Homogeneous moderate influenza vaccine effectiveness against A(H1N1)pdm09 and heterogenous results by country against A(H3N2).

    LENUS (Irish Health Repository)

    Valenciano, Marta

    2015-06-04

    In the first five I-MOVE (Influenza Monitoring Vaccine Effectiveness in Europe) influenza seasons vaccine effectiveness (VE) results were relatively homogenous among participating study sites. In 2013-2014, we undertook a multicentre case-control study based on sentinel practitioner surveillance networks in six European Union (EU) countries to measure 2013-2014 influenza VE against medically-attended influenza-like illness (ILI) laboratory-confirmed as influenza. Influenza A(H3N2) and A(H1N1)pdm09 viruses co-circulated during the season.

  7. Case study - Argentina

    International Nuclear Information System (INIS)

    Antecedents and experience of nuclear activities in Argentina; the Atomic Energy Commission (CNEA). First development and research activities. Research reactors and radioisotopes plants. Health physics and safety regulations. - Feasibility studies for the first nuclear power plant. Awarding the first plant CNA I (Atucha I). Relevant data related to the different project stages. Plant performance. - Feasibility study for the second nuclear power plant. Awarding the second plant CNE (Central Nuclear Embalse). Relevant data related to established targets. Differences compared with the first station targets. Local participation. Plant performance. (orig./GL)

  8. Final report on case studies

    DEFF Research Database (Denmark)

    Ljungberg, Daniel; McKelvey, Maureen; Lassen, Astrid Heidemann

    2012-01-01

    Case study as a research design means investigating a single or multiple instance(s) or setting(s) (i.e. a case) and its entire context to explain a phenomenon and its processes. This is achieved through detailed understanding, usually comprised of multiple sources of information. In this way, ca...

  9. A parathyroid scintigraphy case study

    Energy Technology Data Exchange (ETDEWEB)

    O' Leary, Desiree [UCD School of Diagnostic Imaging, St Anthony' s Campus, Herbert Avenue, Dublin 4 (Ireland)]. E-mail: desiree.oleary@ucd.ie

    2005-05-01

    Background: There has been much debate concerning the most suitable protocol for parathyroid scintigraphy; the merits of various radiopharmaceuticals versus the correct imaging protocol to visualise both ectopic and anatomically placed adenomas against the various equipment choices have been debated. Aim: To demonstrate, through the use of a case study, the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion. Method: Use is made of Tc99mMIBI, full field chest scintigraphy, a clearly defined imaging protocol and SPECT imaging to locate ectopic parathyroid tissue in a female patient with significant symptoms of parathyroid hyperfunction. Results: A single hyperfunctioning adenoma is located in the pre-carinal area of the mediastinum. Using a radioguided surgical technique the hyperfunctioning tissue is excised and confirmed by histopathology. Conclusion: Whilst a dramatic reduction in patient symptoms was not seen immediately in this patient, the symptoms of the illness have been subsiding since January 2003. This case study demonstrates the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion.

  10. Assessing Stewardship Maturity: Use Case Results and Lessons Learned

    Science.gov (United States)

    Ritchey, N. A.; Peng, G.

    2015-12-01

    Assessing the current stewardship maturity state of datasets is an important part of ensuring and improving the way datasets are documented, preserved, stewarded, and disseminated to users. It is a critical step towards meeting U.S. federal regulations, organizational requirements, and user needs, especially in the area of data quality. Stewardship maturity assessment models provide a uniform framework for a consistent assessment within the context of data management in organizations and portfolios, and stewardship of individual datasets, respectively. A key component of dataset and stewardship models maturity is data quality and documentation of the quality. The Data Stewardship Maturity Matrix(DSMM) developed in partnership with NOAA's National Centers of Environmental Information (NCEI) and the Cooperative Institute for Climate and Satellites-North Carolina (CICS-NC) has been used to assess stewardship maturity of highly-utilized datasets within NCEI. Consistent application of the model across heterogenous data types (satellite, in situ, regional, global, etc.) and across multiple levels of stewardship support has proven beneficial but challenging.This presentation will demonstrate the utility of the DSMM through results from use case studies and its application for documenting data quality, indicate the challenges of consistent implementation and provide recommendations on improved application.

  11. Case Study: del Amo Bioventing

    Science.gov (United States)

    The attached presentation discusses the fundamentals of bioventing in the vadose zone. The basics of bioventing are presented. The experience to date with the del Amo Superfund Site is presented as a case study.

  12. Nasopharyngeal Case-Control Study

    Science.gov (United States)

    A case-control study conducted in Taiwan between 1991-1994 among approximately 1,000 individuals to examine the role of viral, environmental, and genetic factors associated with the development of nasopharyngeal carcinoma

  13. A Case Study of Engineering Ethics

    Science.gov (United States)

    Shimizu, Kazuo

    In Engineering Ethics Class at Shizuoka University, the Code of Ethics and Cases for Electrical Engineers by IEEJ Ethics committee is used to promote for high education effect to correspond large number of students (140students). In this paper, a case study in the class, and survey results for ethics value of students are presented. In addition, some comments for role playing act on the case of virtual experiences by students are described.

  14. Educational Potential of Case-Study Technology

    OpenAIRE

    Fedorinova, Zoya Vladimirovna; Vorobyeva, Viktoriya Vladimirovna; Malyanova, Marina

    2015-01-01

    This article presents the results of phenomenological and typological analysis of case-study technology educational potential. The definition “educational potential of case-study technology” is given, the main characteristics of which are changed in communication and collaborative activity quality, appearance of educational initiatives, change of participants’ position in learning process, formation of “collective subject” in collaborative activity, increase of learning (subject) results. Dep...

  15. Summary of case studies for cooperation mechanisms

    DEFF Research Database (Denmark)

    Longa, Francesco Dalla; Klinge Jacobsen, Henrik; Hansen, Lise-Lotte Pade;

    2012-01-01

    This document is a summary report highlighting the main aspect analyzed in the RES4LESS case studies. The document starts with an introductory chapter where the background that led to the selection of the case studies is outlined. In the following three chapters the case studies are presented......, highlighting the most relevant results. A brief chapter concludes the document, giving an outlook on the follow-up activities of the RES4LESS project. This summary is intended not only as an introduction to the RES4LESS cases studies, but also as a guideline to read and interpret the in-depth analysis carried...... out in the final documents that describe the case studies in detail. These documents will be published in September 2012 on the RES4LESS website, www.res4less.eu....

  16. Kenya Groundwater Governance Case Study

    OpenAIRE

    Mumma, Albert; Lane, Michael; Kairu, Edward; Tuinhof, Albert; Hirji, Rafik

    2011-01-01

    This report presents a case study on groundwater governance in Kenya. The objectives of the study were to: (a) describe groundwater resource and socioeconomic settings for four selected aquifers; (b) describe governance arrangements for groundwater management in Kenya; and (c) identify the relevance of these arrangements for planning and implementing climate change mitigation measures. The ...

  17. eCompetence Case Studies

    DEFF Research Database (Denmark)

    Jensen, Helle Bækkelund

    2006-01-01

    In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches.......In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches....

  18. Case Study on Logistics Performance

    Directory of Open Access Journals (Sweden)

    Shahryar Sorooshian

    2013-05-01

    Full Text Available The paper presents research carried out at a medium‐size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and we include a theoretical discussion of online data collected and a case study of the logistic performance of a real organization. The study also examines the performance of the selected company, identifies the problems and provides recommendations for improvements. This study can be a guide for business advisers and those interested in analysing company performance, especially from a logistics viewpoint. We also suggest the methodology of this case study for those who want to have a better understanding of a business environment before starting their own business, or for benchmarking practice during strategic planning.

  19. Predicting Students Drop Out: A Case Study

    Science.gov (United States)

    Dekker, Gerben W.; Pechenizkiy, Mykola; Vleeshouwers, Jan M.

    2009-01-01

    The monitoring and support of university freshmen is considered very important at many educational institutions. In this paper we describe the results of the educational data mining case study aimed at predicting the Electrical Engineering (EE) students drop out after the first semester of their studies or even before they enter the study program…

  20. Post-chikungunya chronic inflammatory rheumatism: results from a retrospective follow-up study of 283 adult and child cases in La Virginia, Risaralda, Colombia [version 2; referees: 3 approved

    Directory of Open Access Journals (Sweden)

    Alfonso J. Rodriguez-Morales

    2016-04-01

    Full Text Available Objective: There are limited studies in Latin America regarding the chronic consequences of the Chikungunya virus (CHIK, such as post-CHIK chronic inflammatory rheumatism (pCHIK-CIR. We assessed the largest cohort so far of pCHIK-CIR in Latin America, at the municipality of La Virginia, Risaralda, a new endemic area of CHIK in Colombia. Methods: We conducted a cohort retrospective study in Colombia of 283 patients diagnosed with CHIK that persisted with pCHIK-CIR after a minimum of 6 weeks and up to a maximum of 26.1 weeks. pCHIK cases were identified according to validated criteria via telephone. Results: Of the total CHIK-infected subjects, 152 (53.7% reported persistent rheumatological symptoms (pCHIK-CIR. All of these patients reported joint pains (chronic polyarthralgia, pCHIK-CPA, 49.5% morning stiffness, 40.6% joint edema, and 16.6% joint redness. Of all patients, 19.4% required and attended for care prior to the current study assessment (1.4% consulting rheumatologists. Significant differences in the frequency were observed according to age groups and gender. Patients aged >40 years old required more medical attention (39.5% than those ≤40 years-old (12.1% (RR=4.748, 95%CI 2.550-8.840. Conclusions: According to our results, at least half of the patients with CHIK developed chronic rheumatologic sequelae, and from those with pCHIK-CPA, nearly half presented clinical symptoms consistent with inflammatory forms of the disease. These results support previous estimates obtained from pooled data of studies in La Reunion (France and India and are consistent with the results published previously from other Colombian cohorts in Venadillo (Tolima and Since (Sucre.

  1. Case Studies in Sports Nutrition.

    Science.gov (United States)

    Clark, Nancy

    1988-01-01

    This article presents case studies of two athletes who wanted to affect a change in their body weight in order to enhance athletic performance. Each athlete's problem and the nutrition approach used to solve it are discussed. Caloric values of fast foods are listed. (JL)

  2. The reflexive case study method

    DEFF Research Database (Denmark)

    Rittenhofer, Iris

    2015-01-01

    This paper extends the international business research on small to medium-sized enterprises (SME) at the nexus of globalization. Based on a conceptual synthesis across disciplines and theoretical perspectives, it offers management research a reflexive method for case study research of postnational...

  3. Imaging screening of breast cancer: primary results in 5307 cases

    International Nuclear Information System (INIS)

    Objective: To discuss the values of three screening methods for the detection of early breast cancer, and to analyze the features of the screening cancer. Methods: The first screening of breast cancer were performed in 5307 women who aged from 20 to 76 years with median age of 49 years. The three screening methods included physical examination with ultrasound and mammography, physical examination with mammography and mammography only. The rate of recall, biopsy, cancer detection of three methods were analyzed and the mammographic findings were reviewed. Chi-square test or Fisher's exact test were used for the statistics. Results: The recall rates were 4.90% (49/1001), 6.90% (166/2407) and 4. 48% (85/1899) in three methods respectively, the biopsy rates were 1.60% (16/1001), 1.04% (25/2407) and 0.63% (12/1899), the cancer detection rates were 0.50% (5/1001), 0.17% (4/2407) and 0 (0/1899). There were statistical differences among the three groups (χ2=12.99,6.264,8.764, P<0.05). Physical examination with ultrasound and mammography had the highest cancer detection rate, ten breast cancers were detected and 8 were early stage breast cancer. Of seven cancers detected by mammography, only two were found by ultrasound. A cluster of calcifications were found in 2 cases, linear calcifications in 2 cases. One case presented as a asymmetric density, one as a asymmetric density with calcifications, one as multiple nodules with a cluster of calcifications. Two breast cancers presented as asymmetric density were missed on mammography and diagnosed correctly after retrospective review. Conclusion: Physical examination with ultrasound and mammography is the best method for breast cancer screening. The breast cancer can be detected by mammography earlier than other methods. (authors)

  4. Concentrated photovoltaics, a case study

    Directory of Open Access Journals (Sweden)

    Antonini Piergiorgio

    2014-01-01

    Full Text Available Concentrated Photovoltaics (CPV, once a niche technology, has now reached the maturity and reliability for large scale power generation. Especially in regions where temperatures are very high, the use of high efficiency triple junction solar cells with concentrating optics allows stable energy yield. Thus CPV can be seen as complementary and not in concurrence with silicon photovoltaics. The state of the art, the advantages and limitations of this technology will be shown. Among the main advantages of CPV is the possibility of a much higher energy supply, when compared to silicon photovoltaics, both comparing CPV and silicon with same area or the same installed power. The use of recycled and recyclable materials allows a more environmentally friendly production. The possibility to couple CPV with desalination facilities, energy storage will be analysed. As an example a case study of a CPV installation in Northern Italy is discussed. Here the use of mature technologies, derived from automotive and lighting sectors resulted in a simple and efficient module.

  5. Genitourinary brucellosis: results of a multicentric study.

    Science.gov (United States)

    Erdem, H; Elaldi, N; Ak, O; Gulsun, S; Tekin, R; Ulug, M; Duygu, F; Sunnetcioglu, M; Tulek, N; Guler, S; Cag, Y; Kaya, S; Turker, N; Parlak, E; Demirdal, T; Ataman Hatipoglu, C; Avci, A; Bulut, C; Avci, M; Pekok, A; Savasci, U; Kaya, S; Sozen, H; Tasbakan, M; Guven, T; Bolukcu, S; Cesur, S; Sahin-Horasan, E; Kazak, E; Denk, A; Gonen, I; Karagoz, G; Haykir Solay, A; Alici, O; Kader, C; Senturk, G; Tosun, S; Turan, H; Baran, A I; Ozturk-Engin, D; Bozkurt, F; Deveci, O; Inan, A; Kadanali, A; Sayar, M S; Cetin, B; Yemisen, M; Naz, H; Gorenek, L; Agalar, C

    2014-11-01

    This study reviewed the clinical, laboratory, therapeutic and prognostic data on genitourinary involvement of brucellosis in this largest case series reported. This multicentre study pooled adult patients with genitourinary brucellar involvement from 34 centres treated between 2000 and 2013. Diagnosis of the disease was established by conventional methods. Overall 390 patients with genitourinary brucellosis (352 male, 90.2%) were pooled. In male patients, the most frequent involved site was the scrotal area (n=327, 83.8%), as epididymo-orchitis (n=204, 58%), orchitis (n=112, 31.8%) and epididymitis (n=11, 3.1%). In female patients, pyelonephritis (n=33/38, 86.8%) was significantly higher than in male patients (n=11/352, 3.1%; pbrucellosis occurred in one patient. A localized scrotal infection in men or pyelonephritis in women in the absence of leucocytosis and with mild to moderate increases in inflammatory markers should signal the possibility of brucellar genitourinary disease.

  6. The Effect of Using Case Studies in Business Statistics

    Science.gov (United States)

    Pariseau, Susan E.; Kezim, Boualem

    2007-01-01

    The authors evaluated the effect on learning of using case studies in business statistics courses. The authors divided students into 3 groups: a control group, a group that completed 1 case study, and a group that completed 3 case studies. Results evidenced that, on average, students whom the authors required to complete a case analysis received…

  7. A Multiple Case Study of Innovation

    Science.gov (United States)

    Zheng, Wei; Khoury, Anne E.

    2008-01-01

    This study aims to explore how leadership and contextual factors influence innovation in R&D teams in national laboratories, using the approach of multiple case studies. This paper provides some preliminary findings from two highly innovative teams residing in two national laboratories in the US. The preliminary results suggested several common…

  8. Common Lunar Lander (CLL) Engineering Study Results

    Science.gov (United States)

    Stecklein, Jonette

    1991-01-01

    Information is given in viewgraph form on the Common Lunar Lander (CLL) engineering study results. The mission is to provide a delivery system to soft-land a 200 kg payload set at any given lunar latitude and longitude. Topics covered include the study schedule, mission goals and requirements, the CLL reference mission, costs, CLL options, and two stage performance analysis.

  9. Returned Solar Max hardware degradation study results

    International Nuclear Information System (INIS)

    The Solar Maximum Repair Mission returned with the replaced hardware that had been in low Earth orbit for over four years. The materials of this returned hardware gave the aerospace community an opportunity to study the realtime effects of atomic oxygen, solar radiation, impact particles, charged particle radiation, and molecular contamination. The results of these studies are summarized

  10. Risk of infectious gastroenteritis in young children living in Québec rural areas with intensive animal farming: results of a case-control study (2004-2007).

    Science.gov (United States)

    Levallois, P; Chevalier, P; Gingras, S; Déry, P; Payment, P; Michel, P; Rodriguez, M

    2014-02-01

    This study was designed to evaluate the epidemiology of severe gastroenteritis in children living in Québec rural areas with intensive livestock activities. From September 2005 through June 2007, 165 cases of gastroenteritis in children aged from 6 months to 5 years, hospitalized or notified to the public health department were enrolled, and 326 eligible controls participated. The parents of cases and controls were asked questions about different gastroenteritis risk factors. The quality of the drinking water used by the participants was investigated for microbial indicators as well as for four zoonotic bacterial pathogens (Campylobacter spp, Escherichia coli, Salmonella spp and Yersinia spp) and two enteric parasites (Cryptosporidium spp and Giardia spp). From 134 stool specimen analysed, viruses were detected in 82 cases (61%), while 28 (21%) were found with at least one of the bacteria investigated, and five cases were infected by parasites. Campylobacteriosis was the main bacterial infection (n = 15), followed by Salmonella sp (n = 7) and E. coli O157:H7 (n = 5) among cases with bacterial gastroenteritis. No significant difference was found between cases and controls regarding the quality of water consumed; the frequency of faecal contamination of private wells was also similar between cases and controls. Considering the total cases (including those with a virus), no link was found between severe gastroenteritis and either being in contact with animals or living in a municipality with the highest animal density (4th quartile). However, when considering only cases with a bacterial or parasite infection (n = 32), there was a weak association with pig density that was not statistically significant after adjusting for potential confounders. Contact with domestic, zoo or farm animals were the only environmental factor associated with the disease.

  11. Microendoscopic lumbar discectomy: Technique and results of 188 cases

    Directory of Open Access Journals (Sweden)

    Arvind G Kulkarni

    2014-01-01

    Full Text Available Background: Discectomy performed open or with an operating microscope remains the standard surgical management. Tubular retractor system is being increasingly used. Potential benefits include less muscle and local damage, better cosmesis, decreased pain and operative time and faster recovery after surgery. We have evaluated the outcome of micro endoscopic discectomy (MED utilizing tubular retractors in terms of safety and efficacy of the technique. Materials and Methods: 188 consecutive patients who underwent surgery for herniated disc using the tubular retractors between April 2007 and April 2012 are reported. All patients had a preoperative MRI (Magnetic Resonance Imaging and were operated by a single surgeon with the METRx system (Medtronic, Sofamor-Danek, Memphis, TN using 18 and 16 mm ports. All patients were mobilized as soon as pain subsided and discharged within 24-48 hours post surgery. The results were evaluated by using VAS (Visual Analog Scale 0-5 for back and leg pain and ODI (Oswestry Disability Index. Patients were followed up at intervals of 1 week, 6 weeks, 3 months, 6 months, 12 months and 2 years. Results: The mean age of patients was 46 years (range 16-78 years and the sex ratio was 1.5 males to 1 female. The mean followup was 22 months (range 8-69 months. The mean VAS scale for leg pain improved from 4.14 to 0.76 ( P < 0.05 and the mean VAS scale for back pain improved from 4.1 to 0.9 ( P < 0.05. The mean ODI changed from 59.5 to 22.6 ( P < 0.05. The mean operative time per level was about 50 minutes (range 20-90 minutes. Dural punctures occurred in 11 (5% cases. Average blood loss was 30 ml (range 10-500 ml. A wrong level was identified and later corrected in a case of revision discectomy. Four patients with residual disc-herniation had revision MED and three patients with recurrent disc herniation later underwent fusion. One patient had wound infection which needed a debridement. Conclusion: MED for herniated discs

  12. A case study of Impetigo

    Directory of Open Access Journals (Sweden)

    Mansouri P

    1993-05-01

    Full Text Available This is a report of a case study on 234 patients with impetigo who referred to Razi Dermatology Hospital from April to November, 1989. Treatment was started immediately after obtaining direct smear and performing culture and antibiotic sensitivity test. The most common organism responsible for impetigo was the coagulase-positive staphylococcus (71%. In 13.7% of the cases, the coagulase-negative staphylococcus was grown on culture media, but none of the cultures showed streptococcus as the main organism. Treatment was started with oral penicillin V, oral erythromycin, benzathine penicillin G injection, oral cephalexin, and topical fuccidin. Clinical and bacteriological evaluation after 3-7 days showed that it is preferable to use oral cephalexin instead of other protocols such as oral erythromycin, which has previously been the drug of choice for impetigo. In addition, topical fuccidin with a 75% curative rate was the first drug for treatment, with the same effect as the oral cephalexin

  13. Sustainability of massively anthropic deltas via dispersal of sediment to manage land building: results from two unique case studies, the Mississippi River (U.S.A.) and the Yellow River (China) deltas

    Science.gov (United States)

    Nittrouer, Jeffrey

    2016-04-01

    Owing to their extraordinary natural resources and ecosystem services, deltaic coastlines host hundreds of millions of people worldwide. Societal sustainability on these coastal landscapes is far from certain, however, due to anthropogenic influences including sediment-supply reduction, accelerated subsidence from sub-surface fluid extraction, and leveeing of rivers. The crucial resource in building stable deltaic coastlines is sediment, and the key control on sediment delivery, whether natural or engineered, is by way river channel diversions. Two case studies, based on previous and ongoing research efforts, are presented here to describe the effects of engineered diversions for the removal of river water and associated sediment: the Mississippi River (U.S.A) and the Yellow River (China). Comparatively speaking, these two systems are end-members: Mississippi River water discharge is five times greater than the Yellow River, and yet historically, the Yellow River sediment discharges five times more sediment than the Mississippi system. As such, diversions for the two systems have contrasting goals. During flood events, the Mississippi water stage threatens major metropolitan regions with levee overtopping; spillways are therefore utilized to reduce water flux through the main channel. For the Yellow River, extremely high sediment loads result in significant sedimentation within the main channel, and so there is a concerted effort to divert and shorten the main channel, in order to enhance the water surface slope and increase sediment transport capacity. Interestingly, the net effect of these two projects has been to deposit a significant amount of sediment into the respective receiving basins, which in turn has led to the development of subaerial land. In essence, this represents two compelling case studies documenting how managed (engineered) land building practices can be implemented for other large fluvial-deltaic systems. Observational data collected from field

  14. Transanal rectopexy - twelve case studies

    Directory of Open Access Journals (Sweden)

    Rubens Henrique Oleques Fernandes

    2012-06-01

    Full Text Available OBJECTIVES: This study analyzed the results of transanal rectopexy and showed the benefits of this surgical technique. METHOD: Twelve patients were submitted to rectopexy between 1997 and 2011. The surgical technique used was transanal rectopexy, where the mesorectum was fixed to the sacrum with nonabsorbable suture. Three patients had been submitted to previous surgery, two by the Delorme technique and one by the Thiersch technique. RESULTS: Postoperative hospital stay ranged from 1 to 4 days. One patient (8.3% had intraoperative hematoma, which was treated with local compression and antibiotics. One patient (8.3% had residual mucosal prolapse, which was resected. Prolapse recurrence was seen in one case (8.3%. Improved incontinence occurred in 75% of patients and one patient reported obstructed evacuation in the first month after surgery. No death occurred. CONCLUSION: Transanal rectopexy is a simple, low cost technique, which has shown good efficacy in rectal prolapse control.OBJETIVO: O presente estudo analisou os resultados da retopexia pela via transanal e expôs os benefícios desta técnica cirúrgica. MÉTODO: Doze pacientes com prolapso foram operados no período de 1997 a 2011. A técnica cirúrgica usada foi a retopexia transanal, onde o mesorreto foi fixado ao sacro com fio inabsorvível. Três pacientes tinham cirurgia prévia, dois pela técnica de Delorme e um pela técnica de Thiersch. RESULTADOS: A permanência hospitalar pós-operatória variou de 1- 4 dias. Uma paciente (8,3% apresentou hematoma transoperatório que foi tratado com compressão local e antibioticoterapia. Um paciente apresentou prolapso mucoso residual (8,3%, que foi ressecado. Houve recidiva da procidência em um caso (8,3%. A melhora da incontinência ocorreu em 75% dos pacientes e uma paciente apresentou bloqueio evacuatório no primeiro mês após a cirurgia. Não houve mortalidade entre os pacientes operados. CONCLUSÃO: A retopexia transanal é uma t

  15. Cryostat design case studies, principles and engineering

    CERN Document Server

    2016-01-01

    This book enables the reader to learn the fundamental and applied aspects of practical cryostat design by examining previous design choices and resulting cryostat performance. Through a series of extended case studies the book presents an overview of existing cryostat design covering a wide range of cryostat types and applications, including the magnet cryostats that comprise the majority of the Large Hadron Collider at CERN, space-borne cryostats containing sensors operating below 1 K, and large cryogenic liquid storage vessels. It starts with an introductory section on the principles of cryostat design including practical data and equations. This section is followed by a series of case studies on existing cryostats, describing the specific requirements of the cryostat, the challenges involved and the design choices made along with the resulting performance of the cryostat. The cryostat examples used in the studies are chosen to cover a broad range of cryostat applications and the authors of each case are ...

  16. Can the management of blood sugar levels in gestational diabetes mellitus cases be an indicator of maternal and fetal outcomes? The results of a prospective cohort study from India

    OpenAIRE

    Rajesh Jain; Sanjeev Davey; Anuradha Davey; Raghav, Santosh K.; Singh, Jai V.

    2016-01-01

    Background: Gestational diabetes mellitus (GDM) is emerging as an important public health problem in India owing to its increasing prevalence since the last decade. The issue addressed in the study was whether the management of blood sugar levels in GDM cases can predict maternal and fetal outcomes. Materials and Methods: A prospective cohort study was done for 1 year from October 1, 2013, to September 31, 2014, at 652 diabetic screening units as a part of the Gestational Diabetes Prevention ...

  17. Low and decreasing vaccine effectiveness against influenza A(H3) in 2011/12 among vaccination target groups in Europe: results from the I-MOVE multicentre case-control study.

    LENUS (Irish Health Repository)

    Kissling, E

    2013-01-01

    Within the Influenza Monitoring Vaccine Effectiveness in Europe (I-MOVE) project we conducted a multicentre case–control study in eight European Union (EU) Member States to estimate the 2011\\/12 influenza vaccine effectiveness against medically attended influenza-like illness (ILI) laboratory-confirmed as influenza A(H3) among the vaccination target groups. Practitioners systematically selected ILI \\/ acute respiratory infection patients to swab within seven days of symptom onset. We restricted the study population to those meeting the EU ILI case definition and compared influenza A(H3) positive to influenza laboratory-negative patients. We used logistic regression with study site as fixed effect and calculated adjusted influenza vaccine effectiveness (IVE), controlling for potential confounders (age group, sex, month of symptom onset, chronic diseases and related hospitalisations, number of practitioner visits in the previous year). Adjusted IVE was 25% (95% confidence intervals (CI): -6 to 47) among all ages (n=1,014), 63% (95% CI: 26 to 82) in adults aged between 15 and 59 years and 15% (95% CI: -33 to 46) among those aged 60 years and above. Adjusted IVE was 38% (95%CI: -8 to 65) in the early influenza season (up to week 6 of 2012) and -1% (95% CI: -60 to 37) in the late phase. The results suggested a low adjusted IVE in 2011\\/12. The lower IVE in the late season could be due to virus changes through the season or waning immunity. Virological surveillance should be enhanced to quantify change over time and understand its relation with duration of immunological protection. Seasonal influenza vaccines should be improved to achieve acceptable levels of protection.

  18. TEACHER BELIEFS: A CASE STUDY

    Institute of Scientific and Technical Information of China (English)

    HuYijie

    2004-01-01

    In recent years ELT has stressed the role which teachers' beliefs play in shaping what they do in the classroom. But so far as teaching English in China is concerned, we lack empirical insight into the relationship between teachers' beliefs and their classroom practice. With specific reference to the use of English in intensive reading classes, by presenting and discussing data from a case study of a non-native college English teacher,this exploratory qualitative classroom research sheds light on the nature of teachers' beliefs held consciously or unconsciously.Their subsequent change and impact on the classroom will also be reported and discussed.

  19. Necrotizing Pancreatitis with Hypertriglyceridemia Development Results: A Case Report

    Directory of Open Access Journals (Sweden)

    Ižbrahim Yetim

    2011-09-01

    Full Text Available Acute pancreatitis due to hypertriglyceridemia is a relatively rare clinical entity. Acute pancreatic necrosis is a life threatening form of acute pancreatitis in which early recognition and treatment is important. Necrotising pancreatitis should be treated immediately. We presented a case of pancreatic necrosis due to hypert¬riglyceridemia which required surgical intervention. We performed necrosectomy. After surgery the patient recovered. We presented the case in order to mention necrotising pancreatitis arising from hypertriglyceridemia and requiring surgical exploration.

  20. Necrotizing Pancreatitis with Hypertriglyceridemia Development Results: A Case Report

    OpenAIRE

    Ibrahim Yetim

    2011-01-01

    Acute pancreatitis due to hypertriglyceridemia is a relatively rare clinical entity. Acute pancreatic necrosis is a life threatening form of acute pancreatitis in which early recognition and treatment is important. Necrotising pancreatitis should be treated immediately. We presented a case of pancreatic necrosis due to hypert¬riglyceridemia which required surgical intervention. We performed necrosectomy. After surgery the patient recovered. We presented the case in order to mention necrot...

  1. Using correspondence analysis in multiple case studies

    NARCIS (Netherlands)

    Kienstra, N.H.H.; van der Heijden, P.G.M.

    2015-01-01

    In qualitative research of multiple case studies, Miles and Huberman proposed to summarize the separate cases in a so-called meta-matrix that consists of cases by variables. Yin discusses cross-case synthesis to study this matrix. We propose correspondence analysis (CA) as a useful tool to study thi

  2. Using Correspondence Analysis in Multiple Case Studies

    NARCIS (Netherlands)

    Kienstra, Natascha; van der Heijden, Peter G.M.

    2015-01-01

    In qualitative research of multiple case studies, Miles and Huberman proposed to summarize the separate cases in a so-called meta-matrix that consists of cases by variables. Yin discusses cross-case synthesis to study this matrix. We propose correspondence analysis (CA) as a useful tool to study thi

  3. WMOST v2 Case Study: Monponsett Ponds

    Science.gov (United States)

    This webinar presents an overview of the preliminary results of a case study application of EPA's Watershed Management Optimization Support Tool v2 (WMOST) for stakeholders in the Monponsett Ponds Watershed Workgroup. Monponsett Ponds is a large water system consisting of two ba...

  4. Learning Machine Learning: A Case Study

    Science.gov (United States)

    Lavesson, N.

    2010-01-01

    This correspondence reports on a case study conducted in the Master's-level Machine Learning (ML) course at Blekinge Institute of Technology, Sweden. The students participated in a self-assessment test and a diagnostic test of prerequisite subjects, and their results on these tests are correlated with their achievement of the course's learning…

  5. Challenges of communicating safety case results to different audiences

    International Nuclear Information System (INIS)

    Nowadays, nuclear politics and decision making are often oriented at procedures which are linked to precautionary concepts and which reflect forms of 'knowledge politics'. These precautionary concepts in most cases focus on robust societal decisions, which incorporate the principles of sustainability as a topic of public debate. The issue of high-level nuclear waste is under debate and confronted with public discourse, which integrates not only the knowledge of different stakeholders, but also accept certain forms of 'Nichtwissen' ('non-knowledge'). Interdisciplinary research has to observe these normative trends and also has to 'contextualise' these questions before interpreting its research results for giving answers with practical relevance, especially in communication with different social actors. Issues which are brought up in this field of nuclear waste management and their social context have to be analysed in two dimensions: i) the dimension of professionalism and expertise; ii) the dimension of managing controversial debates ('knowledge politics') and the preparation and implementing of robust decisions mostly by responsible governmental organisations. In this context on the one hand complex aspects of safety have to be communicated in their internal scientific logic and structure. On the other hand the different functional systems and collective actors of highly differentiated modern societies are engaged in controversial debates on advanced technologies like nuclear energy and technologies for waste disposal over long-lasting time periods. Most safety and construction issues for final disposal of high-level waste, but also of waste management in general, are debated within professional 'communities' of scientists and experts. But if their technological artefacts and their conceptual planning become issues of controversial and political debates in spheres which are outside the closed circle of high-level professionals and party politicians (who are in the

  6. FINAL SIMULATION RESULTS FOR DEMONSTRATION CASE 1 AND 2

    Energy Technology Data Exchange (ETDEWEB)

    David Sloan; Woodrow Fiveland

    2003-10-15

    The goal of this DOE Vision-21 project work scope was to develop an integrated suite of software tools that could be used to simulate and visualize advanced plant concepts. Existing process simulation software did not meet the DOE's objective of ''virtual simulation'' which was needed to evaluate complex cycles. The overall intent of the DOE was to improve predictive tools for cycle analysis, and to improve the component models that are used in turn to simulate equipment in the cycle. Advanced component models are available; however, a generic coupling capability that would link the advanced component models to the cycle simulation software remained to be developed. In the current project, the coupling of the cycle analysis and cycle component simulation software was based on an existing suite of programs. The challenge was to develop a general-purpose software and communications link between the cycle analysis software Aspen Plus{reg_sign} (marketed by Aspen Technology, Inc.), and specialized component modeling packages, as exemplified by industrial proprietary codes (utilized by ALSTOM Power Inc.) and the FLUENT{reg_sign} computational fluid dynamics (CFD) code (provided by Fluent Inc). A software interface and controller, based on an open CAPE-OPEN standard, has been developed and extensively tested. Various test runs and demonstration cases have been utilized to confirm the viability and reliability of the software. ALSTOM Power was tasked with the responsibility to select and run two demonstration cases to test the software--(1) a conventional steam cycle (designated as Demonstration Case 1), and (2) a combined cycle test case (designated as Demonstration Case 2). Demonstration Case 1 is a 30 MWe coal-fired power plant for municipal electricity generation, while Demonstration Case 2 is a 270 MWe, natural gas-fired, combined cycle power plant. Sufficient data was available from the operation of both power plants to complete the cycle

  7. Treatment results in case of advanced tonsillar tumors

    International Nuclear Information System (INIS)

    The authors present 99 patients irradiated for a tonsillar carcinoma. 41 patients were primarily irradiated and 52 patients postoperatively. Radiotherapy was combined with cytostatic chemotherapy in six cases. Most of the cases treated were advanced tumors: 76 patients with T3/T4 tumors. 52% out of the 23 patients with T1/T2 tumors survived five years and 45% ten years; only 26% of the patients with T3 tumors and 15% of those with T4 tumors survived five years. The prognosis was significantly influenced by the lymph node state: whereas 75% of the patients with N0 tumors survived five years, this rate is reduced to 21% in case of lymph node state N3. 22 out of the 34 recurrences were situated in the tumor region, 12 in lymph nodes. 94% of recurrences became evident during the first two years after the end of treatment. (orig.)

  8. AES Water Architecture Study Interim Results

    Science.gov (United States)

    Sarguisingh, Miriam J.

    2012-01-01

    The mission of the Advanced Exploration System (AES) Water Recovery Project (WRP) is to develop advanced water recovery systems in order to enable NASA human exploration missions beyond low earth orbit (LEO). The primary objective of the AES WRP is to develop water recovery technologies critical to near term missions beyond LEO. The secondary objective is to continue to advance mid-readiness level technologies to support future NASA missions. An effort is being undertaken to establish the architecture for the AES Water Recovery System (WRS) that meets both near and long term objectives. The resultant architecture will be used to guide future technical planning, establish a baseline development roadmap for technology infusion, and establish baseline assumptions for integrated ground and on-orbit environmental control and life support systems (ECLSS) definition. This study is being performed in three phases. Phase I of this study established the scope of the study through definition of the mission requirements and constraints, as well as indentifying all possible WRS configurations that meet the mission requirements. Phase II of this study focused on the near term space exploration objectives by establishing an ISS-derived reference schematic for long-duration (>180 day) in-space habitation. Phase III will focus on the long term space exploration objectives, trading the viable WRS configurations identified in Phase I to identify the ideal exploration WRS. The results of Phases I and II are discussed in this paper.

  9. Case Study: A Picture Worth a Thousand Words? Making a Case for Video Case Studies

    Science.gov (United States)

    Pai, Aditi

    2014-01-01

    A picture, they say, is worth a thousand words. If a mere picture is worth a thousand words, how much more are "moving pictures" or videos worth? The author poses this not merely as a rhetorical question, but because she wishes to make a case for using videos in the traditional case study method. She recommends four main approaches of…

  10. STS Case Study Development Support

    Science.gov (United States)

    Rosa de Jesus, Dan A.; Johnson, Grace K.

    2013-01-01

    The Shuttle Case Study Collection (SCSC) has been developed using lessons learned documented by NASA engineers, analysts, and contractors. The SCSC provides educators with a new tool to teach real-world engineering processes with the goal of providing unique educational materials that enhance critical thinking, decision-making and problem-solving skills. During this third phase of the project, responsibilities included: the revision of the Hyper Text Markup Language (HTML) source code to ensure all pages follow World Wide Web Consortium (W3C) standards, and the addition and edition of website content, including text, documents, and images. Basic HTML knowledge was required, as was basic knowledge of photo editing software, and training to learn how to use NASA's Content Management System for website design. The outcome of this project was its release to the public.

  11. KAIZEN – A case study

    Directory of Open Access Journals (Sweden)

    Manjunath Shettar

    2015-05-01

    Full Text Available The ultimate objective of manufacturing industries is to increase productivity with high quality. At present, many manufacturing companies are facing problems such as high quality rejection, high inventories, high lead time, high costs of production, and inability to cope with customer orders. By implementing and practicing the lean production system many problems can be solved without employing high-tech and high-touch approaches but by involving people on the shop floor in Kaizen activities. Kaizen is one of the powerful tools of lean manufacturing. Kaizen refers to continuous improvement in performance, cost and quality. Kaizen ensures that manufacturing processes become leaner and fitter, but eliminate waste (problem where value is added. The main objective of this paper is to provide a background on kaizen, present an overview of kaizen concepts that are used to transform a company into a high performing lean enterprise. A case study of implementation of Kaizen‟s has been discussed.

  12. Percutaneous Treatment of Splenic Cystic Echinococcosis: Results of 12 Cases

    Energy Technology Data Exchange (ETDEWEB)

    Akhan, Okan, E-mail: akhano@tr.net; Akkaya, Selçuk, E-mail: selcuk.akkaya85@gmail.com [Hacettepe University, Department of Radiology, School of Medicine (Turkey); Dağoğlu, Merve Gülbiz, E-mail: drmgkartal@gmail.com [Istanbul University, Department of Radiology, Istanbul School of Medicine (Turkey); Akpınar, Burcu, E-mail: burcu-akpinar@yahoo.com [Hacettepe University, Department of Radiology, School of Medicine (Turkey); Erbahçeci, Aysun, E-mail: aysunerbahceci@yahoo.com [Istanbul Bakirkoy Dr. Sadi Konuk Education and Research Hospital, Department of Radiology (Turkey); Çiftçi, Türkmen, E-mail: turkmenciftci@yahoo.com [Hacettepe University, Department of Radiology, School of Medicine (Turkey); Köroğlu, Mert, E-mail: mertkoroglu@hotmail.com [Antalya Education and Research Hospital, Department of Radiology (Turkey); Akıncı, Devrim, E-mail: akincid@hotmail.com [Hacettepe University, Department of Radiology, School of Medicine (Turkey)

    2016-03-15

    PurposeCystic echinococcosis (CE) in the spleen is a rare disease even in endemic regions. The aim of this study was to examine the efficacy of percutaneous treatment for splenic CE.Materials and MethodsTwelve patients (four men, eight women) with splenic CE were included in this study. For percutaneous treatment, CE1 and CE3A splenic hydatid cysts were treated with either the PAIR (puncture, aspiration, injection, respiration) technique or the catheterization technique.ResultsEight of the hydatid cysts were treated with the PAIR technique and four were treated with catheterization. The volume of all cysts decreased significantly during the follow-up period. No complication occurred in seven of 12 patients. Abscess developed in four patients. Two patients underwent splenectomy due to cavity infection developed after percutaneous treatment, while the spleen was preserved in 10 of 12 patients. Total hospital stay was between 1 and 18 days. Hospital stay was longer and the rate of infection was higher in the catheterization group. Follow-up period was 5–117 months (mean, 44.8 months), with no recurrence observed.ConclusionThe advantages of the percutaneous treatment are its minimal invasive nature, short hospitalization duration, and its ability to preserve splenic tissue and function. As the catheterization technique is associated with higher abscess risk, we suggest that the PAIR procedure should be the first percutaneous treatment option for splenic CE.

  13. Percutaneous Treatment of Splenic Cystic Echinococcosis: Results of 12 Cases

    International Nuclear Information System (INIS)

    PurposeCystic echinococcosis (CE) in the spleen is a rare disease even in endemic regions. The aim of this study was to examine the efficacy of percutaneous treatment for splenic CE.Materials and MethodsTwelve patients (four men, eight women) with splenic CE were included in this study. For percutaneous treatment, CE1 and CE3A splenic hydatid cysts were treated with either the PAIR (puncture, aspiration, injection, respiration) technique or the catheterization technique.ResultsEight of the hydatid cysts were treated with the PAIR technique and four were treated with catheterization. The volume of all cysts decreased significantly during the follow-up period. No complication occurred in seven of 12 patients. Abscess developed in four patients. Two patients underwent splenectomy due to cavity infection developed after percutaneous treatment, while the spleen was preserved in 10 of 12 patients. Total hospital stay was between 1 and 18 days. Hospital stay was longer and the rate of infection was higher in the catheterization group. Follow-up period was 5–117 months (mean, 44.8 months), with no recurrence observed.ConclusionThe advantages of the percutaneous treatment are its minimal invasive nature, short hospitalization duration, and its ability to preserve splenic tissue and function. As the catheterization technique is associated with higher abscess risk, we suggest that the PAIR procedure should be the first percutaneous treatment option for splenic CE

  14. Empathy Development Through Case Study and Simulation.

    Science.gov (United States)

    Mennenga, Heidi A; Bassett, Susan; Pasquariello, Libby

    2016-01-01

    Because empathy is integral to the nurse-patient relationship, nurse educators are challenged to explore teaching strategies that may aid in the development of empathy among students. The purpose of this study was to determine whether consistent exposure to a single patient through case study and simulation had an impact on empathy levels in senior-level baccalaureate nursing students. Results provide interesting conclusions for faculty members and offer a basis for ongoing discussion.

  15. Success against the odds: A case study

    OpenAIRE

    Ahmadbayli, Aydan

    2015-01-01

    The purpose of this dissertation is to examine the leadership behaviours and practices necessary for school ‘turnaround’. The research was conducted by taking a multi perspective approach within a qualitative research study to explore the case of a UK based school facing ‘special measures’ and in disadvantaged circumstances. Research methods employed include a documentary study and semi-structured interviews with six members of staff. The results indicated that effective turnaround leaders em...

  16. Fixed drug eruption resulting from fluconazole use: a case report

    Directory of Open Access Journals (Sweden)

    Tavallaee Mahkam

    2009-07-01

    Full Text Available Abstract Introduction Fluconazole is a widely used antifungal agent with a possible side effect of fixed drug eruption. However, this adverse drug effect is absent from the reported list of possible side effects of fluconazole. We are presenting a rare case in our report. Case presentation A 25-year-old Iranian woman developed fixed drug eruptions on different sites of her body after taking five doses of fluconazole to treat vaginal candidiasis. A positive patch test, positive oral challenge test and skin biopsy were all found to be consistent with fixed drug eruption. Conclusion Fluconazole is a widely prescribed drug, used mainly to treat candidiasis. Fixed drug eruption as a possible side effect of Fluconazole is not well known and thus, the lesions may be misdiagnosed and mistreated. Based on our findings, which are consistent with a number of other practitioners, we recommend adding fixed drug eruption to the list of possible side effects of fluconazole.

  17. Using Case Studies To Teach Science.

    Science.gov (United States)

    Gabel, Connie

    Using case studies in science instruction develops problem solving and enhances listening and cooperative learning skills. Unlike other disciplines such as law and medicine, the case study method is rarely used in science education to enrich the curriculum. This study investigates the use of content-based case studies as a means of developing…

  18. Recurrent perinatal loss: a case study.

    Science.gov (United States)

    Kavanaugh, K; Robertson, P A

    1999-01-01

    To date, investigators have not demonstrated a clear relationship between a parent's history of prior perinatal losses and intensity of grief response following a subsequent perinatal loss. Examining this relationship for low-income, African-American parents is important because they are a vulnerable population due to the high incidence of perinatal mortality in Blacks and their other life stressors that can impact on grief response and caring needs. The purpose of this case study was to examine the impact of recurrent perinatal loss on a low-income African-American parent. The research design for this study was case report, using interview data collected from a mother who had recently experienced her fourth perinatal loss, which occurred at twenty-five weeks of gestation. Transcripts from two open-ended interviews were analyzed. The theoretical framework used to guide analysis of this case study was Lazarus and Folkman's stress and coping theory. Results demonstrated that the prior perinatal losses did not appear as critical components of the way the mother responded to her most recent loss. Instead, perception of the care she received from healthcare providers and how that care related to her experiences with her one living child who was born at the same gestational age was an important determinant in how she responded to her loss. The results of this case study demonstrate the importance assessing a person's perception of their experience and those factors which contribute to the way they respond.

  19. Acoustical case studies of three green buildings

    Science.gov (United States)

    Siebein, Gary; Lilkendey, Robert; Skorski, Stephen

    2005-04-01

    Case studies of 3 green buildings with LEED certifications that required extensive acoustical retrofit work to become satisfactory work environments for their intended user groups will be used to define areas where green building design concepts and acoustical design concepts require reconciliation. Case study 1 is an office and conference center for a city environmental education agency. Large open spaces intended to collect daylight through clerestory windows provided large, reverberant volumes with few acoustic finishes that rendered them unsuitable as open office space and a conference room/auditorium. Case Study 2 describes one of the first gold LEED buildings in the southeast whose primary design concepts were so narrowly focused on thermal and lighting issues that they often worked directly against basic acoustical requirements resulting in sound levels of NC 50-55 in classrooms and faculty offices, crosstalk between classrooms and poor room acoustics. Case study 3 is an environmental education and conference center with open public areas, very high ceilings, and all reflective surfaces made from wood and other environmentally friendly materials that result in excessive loudness when the building is used by the numbers of people which it was intended to serve.

  20. Invasive aspergillosis: results of multicenter study

    Directory of Open Access Journals (Sweden)

    N. N. Klimko

    2014-01-01

    Full Text Available We present the results of a multicenter study of 445 patients with “proven” and “probable” invasive aspergillosis (EORTC/MSG, 2008. Invasive aspergillosis usually occurs in patients with hematological malignancies (88 %, main underlying diseases were acute myeloid and acute lymphoblastic leukemia. The risk factors: prolonged agranulocytosis (64 %, cytostatic chemotherapy (57 %, corticosteroid treatment (45 %, and allogeneic hematopoietic stem cells transplantation (29 %. The pathogens – A. fumigatus (42 %, A. niger (33 %, and A. flavus (21 %. The main site of infection were lungs (86 %. 12 week overall survival was 83 %. Bronchoscopy use for the early diagnosis (p = 0.01, adequatetherapy with voriconazole (p = 0.002 and secondary antifungal prophylaxis (p = 0.0003 were positive prognostic factors for survival of patients with invasive aspergillosis.

  1. Invasive aspergillosis: results of multicenter study

    Directory of Open Access Journals (Sweden)

    N. N. Klimko

    2014-09-01

    Full Text Available We present the results of a multicenter study of 445 patients with “proven” and “probable” invasive aspergillosis (EORTC/MSG, 2008. Invasive aspergillosis usually occurs in patients with hematological malignancies (88 %, main underlying diseases were acute myeloid and acute lymphoblastic leukemia. The risk factors: prolonged agranulocytosis (64 %, cytostatic chemotherapy (57 %, corticosteroid treatment (45 %, and allogeneic hematopoietic stem cells transplantation (29 %. The pathogens – A. fumigatus (42 %, A. niger (33 %, and A. flavus (21 %. The main site of infection were lungs (86 %. 12 week overall survival was 83 %. Bronchoscopy use for the early diagnosis (p = 0.01, adequatetherapy with voriconazole (p = 0.002 and secondary antifungal prophylaxis (p = 0.0003 were positive prognostic factors for survival of patients with invasive aspergillosis.

  2. Catalog of NASA-Related Case Studies

    Data.gov (United States)

    National Aeronautics and Space Administration — The OCKO has developed over 50 case studies to enhance learning at workshops, training, retreats and conferences. Case studies make mission knowledge attractive and...

  3. RESULTS OF SURGICAL TREATMENT IN CERVICAL HERNIATED DISC ANALYSIS OF 275 CASES

    Directory of Open Access Journals (Sweden)

    L. Eva

    2010-02-01

    Full Text Available Background: Problems of surgical treatment of cervical disc hernia are still far from being resolved. It shows variety of surgical procedures it. The operations for cervical level with radiculopatie were quite limited. Limits method were dictated by the absence of accurate diagnosis, microsurgical methods, extensions, sometimes unjustified, conservative treatment. Material and method Complex issue of cervical spine degenerative pathologies, particularly cervical disc hernia with radicular syndrome was studied on a group of 275 patients. Results: From the 275 patients with herniated disc cervical admitted in the study, 182 (66.18% of cases had surgical intervention to a single level disc, 72 patients (26.18% of cases in two levels, 20 patients (7.27% cases at three levels and one case (0.36% at four levels.

  4. A Giant Case of Pyonephrosis Resulting from Nephrolithiasis

    Directory of Open Access Journals (Sweden)

    Ali Erol

    2014-01-01

    Full Text Available Pyonephrosis is an uncommon disease that is associated with suppurative destruction of the renal parenchyma in adults. Upper urinary tract infection and obstruction play a role in its etiology. Immunosuppression from medications (steroids, diseases (diabetes mellitus, AIDS, and anatomic variations (pelvic kidney, horseshoe kidney may also be risk factors for pyonephrosis. Fever, shivering, and flank pain are frequent clinical symptoms. On physical examination, a palpable abdominal mass may be associated with the hydronephrotic kidney. Septic shock and death can occur if the disorder is not treated with urgent surgery. After the acute phase, most patients are treated with nephrectomy. In this paper, we share the etiology, clinical features, diagnosis and treatment of pyonephrosis using the background of a case with giant pyonephrosis developing due to a kidney stone, the most common cause of upper urinary tract obstruction.

  5. Radiative damping: a case study

    CERN Document Server

    Spohn, Herbert

    2011-01-01

    We are interested in the motion of a classical charge coupled to the Maxwell self-field and subject to a uniform external magnetic field, B. This is a physically relevant, but difficult dynamical problem, to which contributions range over more than one hundred years. Specifically, we will study the Sommerfeld-Page approximation which assumes an extended charge distribution at small velocities. The memory equation is then linear and many details become available. We discuss how the friction equation arises in the limit of "small" B and contrast this result with the standard Taylor expansion resulting in a second order equation for the velocity of the charge.

  6. Brick handling: a case study.

    Science.gov (United States)

    Webb, R D; Handyside, J

    1982-09-01

    A small change in brick dimensions resulted in an increase in the perceived work-load of men loading and unloading pallets of bricks by hand. A laboratory study indicated that the change in brick dimensions required changes in grip pattern in order to unload bricks at the same rate, moving the same number at a time. These changed grip patterns resulted in increased upper body movement, increased chest-muscle activity and higher heart rates. These differences were reflected in higher subjective ratings of fatigue. PMID:15676442

  7. A Codesign Case Study in Computer Graphics

    OpenAIRE

    Brage, Jens P.; Madsen, Jan

    1994-01-01

    The paper describes a codesign case study where a computer graphics application is examined with the intention to speed up its execution. The application is specified as a C program, and is characterized by the lack of a simple compute-intensive kernel. The hardware/software partitioning is based on information obtained from software profiling and the resulting design is validated through cosimulation. A locally developed interface model, Merlin, is used as the basis for co-simulation. The ac...

  8. Web Fuzzy Clustering and a Case Study

    Institute of Scientific and Technical Information of China (English)

    LIU Mao-fu; HE Jing; HE Yan-xiang; HU Hui-jun

    2004-01-01

    We combine the web usage mining and fuzzy clustering and give the concept of web fuzzy clustering, and then put forward the web fuzzy clustering processing model which is discussed in detail. Web fuzzy clustering can be used in the web users clustering and web pages clustering. In the end, a case study is given and the result has proved the feasibility of using web fuzzy clustering in web pages clustering.

  9. Systemic Design: Two Canadian Case Studies

    OpenAIRE

    Alex Ryan; Mark Leung

    2014-01-01

    This paper introduces two novel applications of systemic design to facilitate a comparison of alternative methodologies that integrate systems thinking and design. In the first case study, systemic design helped the Procurement Department at the University of Toronto re-envision how public policy is implemented and how value is created in the broader university purchasing ecosystem. This resulted in an estimated $1.5 million in savings in the first year, and a rise in user retention rates fro...

  10. Correlating Pap Smear Results and Colposcopy-Directed Large Loop Excision of the Transformation Zone Histopathology in HIV-Infected and HIV-Uninfected Women: A Case-Control Study in South Africa

    Directory of Open Access Journals (Sweden)

    Louis-J. van Bogaert

    2013-01-01

    Full Text Available Background. In low-resource settings (LRS with high HIV/AIDS and cervical cancer rates, new screening strategies face many logistic hurdles. Since cytology is there to stay, at least in the median-term future, it is important to assess to what extent HIV-HPV coinfection impacts the accuracy of screening methods and strategies. Methods. We audited the correlation between cytological diagnosis of minimal abnormality (CIN1, CIN2+, or cancer and the histological diagnosis of colposcopy-directed large loop excision of the transformation zone of 399 HIV-uninfected controls and 389 HIV-infected cases. Results. The average age at diagnosis of CIN2+ of the cases was 4.2 years younger than controls (. The endpoint used to assess the accuracy of cytology was minimal cytological abnormality (≤CIN1/LGSIL. The sensitivity, specificity, and negative and positive predictive values were 92.7, 18.5, 45.1, and 77.9%, respectively. The overall ratio of discordance/concordance between cytology and histology was similar in both groups. Conclusion. In LRS, where rapid-HPV testing is not yet part of screening algorithms, a cytological diagnosis of minimal abnormality requires visual inspection and treatment of visualized lesions especially in HIV-infected women aged 30 years. The cytological endpoint of accuracy should be set low to avoid false negative smears.

  11. A HARD CHOICE (CASE STUDY)

    OpenAIRE

    KRAVCHENKO NATALIYA A.; KUZNETSOVA SVETLANA A.

    2014-01-01

    The case describes the problems of strategic choice: a small company successfully working in the engineering market (automation of technological processes) in the electric power industry has to make a decision on its further development in a changing external environment and increased competition. The case was carried out to be used in training programs of different levels within the courses “Strategic Management”, “Innovation Management”, “Strategic Analysis Methods”, “Change Management” whe...

  12. Chordoma. Report on treatment results in eighteen cases

    Energy Technology Data Exchange (ETDEWEB)

    Lybeert, M.L.M.; Meerwaldt, J.H.

    1986-01-15

    Eighteen patients with a proven histologic diagnosis of chordoma were treated between 1949 and 1982. Four patients received only surgery, 4 patients only radiation therapy, and 10 patients received surgery and postoperative radiation therapy to a varying dose. The results suggest that a higher radiation dose gives longer recurrence-free survival, and that the best long term results can be achieved by combining surgery - as radically as possible - with radiation therapy to a dose level of 60 to 65 Gy. In view of the number of marginal recurrences (2 out of the 14 patients who received radiation therapy), the importance of choosing the right treatment volume is stressed.

  13. Linguistic Overgeneralization: A Case Study

    Directory of Open Access Journals (Sweden)

    Wasan Nazar Al-Baldawi

    2011-08-01

    Full Text Available The current study described a single child’s language acquisition. The importance of this study resided in the circumstances and the environment in which the child lived. He came from a family in which the parents were from different countries and cultures; spoke different Arabic dialects and who lived in a country in which English is spoken. The child was in his critical period of language acquisition. He seemed to have established a unique way of communicating with people surrounding him to cope with all the linguistic varieties around him. The study showed that the child had semantic, syntactic and morphological overgeneralized structures. The data and results showed that overgeneralization and language acquisition were primarily an innate faculty of the human mind and that imitation did played a primary role in language acquisition.It showed, nevertheless, that imitation and behaviorist approaches could not fully account for language acquisition nor did the generative approach. The results went in favor of an Emergentist approach of language acquisition where both innateness and imitations were crucial constituents of children’s acquisition of linguistic forms.

  14. [Results of a case-control study of the current effect of various factors on risk of cervix cancer. 1. Factors in reproduction, sex behavior and infectious genital diseases].

    Science.gov (United States)

    Köhler, U; Wuttke, P

    1994-01-01

    We performed a case control study to determine factors which influence the development of cervical carcinoma. Factors like reproduction, sexual behaviour and genital infections were considered. 309 patients with cervical intraepithelial neoplasia (CIN) or invasive cervical carcinoma were interviewed as a study group. 490 patients with no cervical changes served as control group. The two groups of patients had a different age distribution with an early age summit in the study group. No differences were observed in relation to residence areas and attendance of screening for cervical carcinoma. 83.5% of the women in the study group (n = 258) and 81.0% (n = 397) of the control group attended the screening for cervical carcinoma. According to our observation, the following factors increased the risk of CIN or invasive cervical carcinoma: early menarche ( 14 years), multiparity (0 vs 1-3 vs > 4), first pregnancy before the age of 20, divorced women, early sexual contact ( 21 years), multiple sexual partners, vaginal discharge and venereal diseases (gonorrhea, syphilis). Factors like reproductive characteristics and genital infections can be interpreted as expressions of sexual behaviour. Despite the improving social status, increasing health consciousness and extensive mass-screening for cervical cancer, the above mentioned risk factors still play an important role. Risk group should be followed and examined strictly so as to reduce the rate of invasive cervical carcinoma in screened patients. PMID:8048284

  15. HIV transmission as a result of drug market violence: a case report

    Directory of Open Access Journals (Sweden)

    Kerr Thomas

    2008-07-01

    Full Text Available Abstract While unprotected sexual intercourse and the use of contaminated injection equipment account for the majority of HIV infections worldwide, other routes of HIV transmission have received less attention. We report on a case of HIV transmission attributable to illicit drug market violence involving a participant in a prospective cohort study of injection drug users. Data from a qualitative interview was used in addition to questionnaire data and nursing records to document an episode of violence which likely resulted in this individual acquiring HIV infection. The case report demonstrates that the dangers of drug market violence go beyond the immediate physical trauma associated with violent altercations to include the possibility for infectious disease transmission. The case highlights the need to consider antiretroviral post-exposure prophylaxis in cases of drug market violence presenting to the emergency room, as well strategies to reduce violence associated with street-based drug markets.

  16. Results of six years of cytogenetic studies in amniotic fluid

    Directory of Open Access Journals (Sweden)

    Enelis Reyes Reyes

    2015-10-01

    Full Text Available Background: research into different genetic diseases is one of the preventive programs of paramount importance at public health level. The early detection of chromosomopathies and the establishment of an appropriate strategy reduce the morbidity-morality rate and improve the patients’ quality of life.Objective: to describe the behavior of the results of the cytogenetic studies in the amniotic fluid of pregnant women from Las Tunas province during six years: from 2008 to 2014.Methods: a retrospective and descriptive study was carried out to assess the results of cytogenetic studies in amniotic liquid during six years: from 2008 to 2014. The statistical records were checked and the results, the indication criteria, the behavior of the age groups in women advanced in age and the diagnosed chromosomopathies were assessed.Results: the samples with results that exceeded the non-conclusive and positive women prevailed; 2, 3 positive cases of chromosomopathies were diagnosed out of 100 studied women at risk; pregnant women of advanced gestational years prevailed as indication criterion, being the 37 to 40 years old age group the predominant one; in the positive cases, numeric chromosomopathies of the type trisomy 21 or Down’s syndrome prevailed, with a frequency of 1, 2 out of 100 pregnant women at risk.Conclusions: the program of the cytogenetic diagnosis in the amniotic fluid has been an effective tool to detect congenital prenatal defects by chromosomopathies, very useful in the process of genetic advice.

  17. Five misunderstandings about case study research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2004-01-01

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...... useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one...... and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without exemplars is an ineffective one. Social science may be strengthened by the execution of more...

  18. Five misunderstandings about Case-study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...... useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one...... and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without  exemplars is an ineffective one. Social science may be strengthened by the execution of more...

  19. Five Misunderstandings About Case-Study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2006-01-01

    This article examines five common misunderstandings about case-study research: (a) theoretical knowledge is more valuable than practical knowledge; (b) one cannot generalize from a single case, therefore, the single-case study cannot contribute to scientific development; (c) the case study is most...... useful for generating hypotheses, whereas other methods are more suitable for hypotheses testing and theory building; (d) the case study contains a bias toward verification; and (e) it is often difficult to summarize specific case studies. This article explains and corrects these misunderstandings one...... by one and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and a discipline without exemplars is an ineffective one. Social science may be strengthened by the execution...

  20. Systemic Design: Two Canadian Case Studies

    Directory of Open Access Journals (Sweden)

    Alex Ryan

    2014-12-01

    Full Text Available This paper introduces two novel applications of systemic design to facilitate a comparison of alternative methodologies that integrate systems thinking and design. In the first case study, systemic design helped the Procurement Department at the University of Toronto re-envision how public policy is implemented and how value is created in the broader university purchasing ecosystem. This resulted in an estimated $1.5 million in savings in the first year, and a rise in user retention rates from 40% to 99%. In the second case study, systemic design helped the clean energy and natural resources group within the Government of Alberta to design a more efficient and effective resource management system and shift the way that natural resource departments work together. This resulted in the formation of a standing systemic design team and contributed to the creation of an integrated resource management system. A comparative analysis of the two projects identifies a shared set of core principles for systemic design as well as areas of differentiation that reveal potential for learning across methodologies. Together, these case studies demonstrate the complementarity of systems thinking and design thinking, and show how they may be integrated to guide positive change within complex sociotechnical systems.

  1. Dieulafoy's lesion: A case series study

    Institute of Scientific and Technical Information of China (English)

    RS Walmsley; Yuk-Tong Lee; Joseph JY Sung

    2005-01-01

    AIM: Dieulafoy's lesion (DL) accounts for 1-5.8% of cases of acute upper gastrointestinal bleeding (GIB). Its mortality is high, approaching 20%, despite recent advances in endoscopic therapy. We aimed to report our experience in the treatment of DL.METHODS: A retrospective case study of all patients with DL between January 1993 and January 2003 was done. Characteristics, treatment methods, success rates and 30-d mortality of the patients were analyzed. RESULTS: Thirty-six patients were noted to have DL in the study period. Thirty-three records were available for assessment in which 35 DL were identified. The median age of the patients was 67 years with male to female ratio of 5.6:1. Significant comorbidities existed in 69% of the patients. Eighty-nine percent of the DL was found at first endoscopy, three DL at laparotomy. Significant coexistent endoscopic findings existed in 23%. Hemostasis was achieved in 88% by using adrenaline injection, or in combination with heater probe application at first endoscopy. Four cases had re-bleeding, all were successfully treated endoscopically. The 30-d mortality rate was 23%.CONCLUSION: Successful endoscopic hemostasis could be achieved in 100% of cases of DL. The overall mortality may still remain high, mainly due to the comorbidities and age of these patients.

  2. Marketing and clinical trials: a case study

    Directory of Open Access Journals (Sweden)

    Entwistle Vikki A

    2007-11-01

    Full Text Available Abstract Background Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous manner and are managed well, adopting effective marketing strategies. Methods Using methods of analysis drawn from management studies, this paper presents a structured assessment framework or reference model, derived from a case analysis of the MRC's CRASH trial, of 12 factors that may affect the success of the marketing and sales activities associated with clinical trials. Results The case study demonstrates that trials need various categories of people to buy in – hence, to be successful, trialists must embrace marketing strategies to some extent. Conclusion The performance of future clinical trials could be enhanced if trialists routinely considered these factors.

  3. The ABC Schizophrenia Study: a preliminary overview of the results.

    Science.gov (United States)

    Häfner, H; Maurer, K; Löffler, W; an der Heiden, W; Munk-Jørgensen, P; Hambrecht, M; Riecher-Rössler, A

    1998-08-01

    The ABC Schizophrenia Study, a large-scale epidemiological and neurobiological research project commenced in 1987, initially pursued two aims: (1) to elucidate the possible causes of the sex difference in age at first admission for schizophrenia and (2) to analyse the early course of the disorder from onset until first contact and its implications for further course and outcome. First, transnational case-register data (for Denmark and Germany) were compared, second, a population-based sample of first-episode cases of schizophrenia (n = 232) were selected and third, the results obtained were compared with data from the WHO Determinants of Outcome Study by using a systematic methodology. A consistent result was a 3-4 years higher age of onset for women by any definition of onset, which was not explainable by social variables, such as differences in the male-female societal roles. A sensitivity-reducing effect of oestrogen on central D2 receptors was identified as the underlying neurobiological mechanism in animal experiments. Applicability to humans with schizophrenia was established in a controlled clinical study. A comparison of familial and sporadic cases showed that in cases with a high genetic load, the sex difference in age of onset disappeared due to a clearly reduced age of onset in women, whereas in sporadic cases it increased. To analyse early course retrospectively, a semistructured interview, IRAOS, was developed. The early stages of the disorder were reconstructed in comparison with age- and sex-matched controls from the same population of origin. The initial signs consisted mainly of negative and affective symptoms, which accumulated exponentially until the first episode, as did the later emerging positive symptoms. Social disability appeared 2-4 years before first admission on average. In early-onset cases, social course and outcome, studied prospectively over 5 years, was determined by the level of social development at onset through social stagnation

  4. Neuropathology of supercentenarians - four autopsy case studies.

    Science.gov (United States)

    Takao, Masaki; Hirose, Nobuyoshi; Arai, Yasumichi; Mihara, Ban; Mimura, Masaru

    2016-01-01

    Supercentenarians (aged 110 years old or more) are extremely rare in the world population (the number of living supercentenarians is estimated as 47 in the world), and details about their neuropathological information are limited. Based on previous studies, centenarians (aged 100-109 years old) exhibit several types of neuropathological changes, such as Alzheimer's disease and Lewy body disease pathology, primary age-related tauopathy, TDP-43 pathology, and hippocampal sclerosis. In the present study, we provide results from neuropathological analyses of four supercentenarian autopsy cases using conventional and immunohistochemical analysis for neurodegenerative disorders. In particular, we focused on the pathology of Alzheimer's disease and Lewy body disease, as well as the status of hippocampal sclerosis, TDP-43 pathology, aging-related tau astrogliopathy, and cerebrovascular diseases. Three cases were characterized as an "intermediate" level of Alzheimer's disease changes (NIA-AA guideline) and one was characterized as primary age-related tauopathy. TDP-43 deposits were present in the hippocampus in two cases. Neither Lewy body pathology nor hippocampal sclerosis was observed. Aging-related tau astrogliopathy was consistently observed, particularly in the basal forebrain. Small vessel diseases were also present, but they were relatively mild for cerebral amyloid-beta angiopathy and arteriolosclerosis. Although our study involved a small number of cases, the results provide a better understanding about human longevity. Neuropathological alterations associated with aging were mild to moderate in the supercentenarian brain, suggesting that these individuals might have some neuroprotective factors against aging. Future prospective studies and extensive molecular analyses are needed to determine the mechanisms of human longevity. PMID:27590044

  5. Case study of isosurface extraction algorithm performance

    Energy Technology Data Exchange (ETDEWEB)

    Sutton, P M; Hansen, C D; Shen, H; Schikore, D

    1999-12-14

    Isosurface extraction is an important and useful visualization method. Over the past ten years, the field has seen numerous isosurface techniques published leaving the user in a quandary about which one should be used. Some papers have published complexity analysis of the techniques yet empirical evidence comparing different methods is lacking. This case study presents a comparative study of several representative isosurface extraction algorithms. It reports and analyzes empirical measurements of execution times and memory behavior for each algorithm. The results show that asymptotically optimal techniques may not be the best choice when implemented on modern computer architectures.

  6. Shippingport aging studies: Results and plans

    International Nuclear Information System (INIS)

    The objective of this program is to develop an understanding of the metallurgical phenomena that may occur in nuclear reactor structural materials as a consequence of extended service at operating temperatures within and outside of the radiation environment and to assess the impact of these phenomena on structural integrity. Although many aging phenomena such as the embrittlement of cast stainless steel, low-temperature sensitization of austenitic stainless steels, and radiation embrittlement of pressure vessel steels have been studied in the laboratory, most of the studies have been based on simulation of actual reactor conditions. The Shippingport reactor offers a unique opportunity to validate and benchmark the laboratory studies, and thereby, provide a sound basis for evaluating the integrity of structural components near the end of the projected life of the plant. Additional work will be undertaken to identify the possibility of new, previously unknown mechanisms of component degradation. 6 refs., 10 figs., 6 tabs

  7. Drive Electric Vermont Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Fred [Energetics Incorporated, Columbia, MD (United States); Roberts, Dave [Vermont Energy Investment Corporation (VEIC), Burlington, VT (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States); White, Sera [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    Currently in the United States, the heavy majority of plug-in electric vehicle (PEV) sales have been in highly conducive, selected, metropolitan areas; opposed to more broad distribution across the country. The U.S. Department of Energy’s EV Everywhere Grand Challenge is looking carefully at the barriers and opportunities that exist to enable small and midsize communities to partake in the PEV market and benefit from the economic and environmental advantages of PEVs. In order to gain insight into these challenges and barriers, DOE selected a success story (i.e., Drive Electric Vermont) as the subject of this case study, as the state of Vermont is tied with Detroit, Michigan in having the highest percentage of 2014 (most recent complete data) PEV registrations for cold weather U.S. cities and has seen more than a sixfold increase in charging stations over the last three years. The overall objective of this case study was to use the lessons learned from Drive Electric Vermont to determine what activities are most effective at encouraging acquisitions of PEVs and deployment of charging infrastructure in small to midsize communities, prioritizing and sequencing their implementation, identifying robust means for extrapolation, and applying this understanding to other small to midsize communities across the nation. The Drive Electric Vermont Program was formed in 2012 with a goal of increasing the use of electrified transportation in Vermont through policy development, education and outreach, and infrastructure development. The Drive Electric Vermont Program can be broadly broken into four components: (1) strategic planning/leadership, (2) stakeholder/partnership development, (3) education and outreach, and (4) incentives. The early phases of the program focused heavily on strategic planning, and stakeholder and partnership development, followed by a transition to education and outreach activities, charging infrastructure development, and grant and incentive programs

  8. Drive Electric Vermont Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Fred [Energetics Incorporated, Columbia, MD (United States); Roberts, Dave [Vermont Energy Investment Corporation (VEIC), Burlington, VT (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States); White, Sera [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    Currently in the United States, the heavy majority of plug-in electric vehicle (PEV) sales have been in highly conducive, selected, metropolitan areas; opposed to more broad distribution across the country. The U.S. Department of Energy’s EV Everywhere Grand Challenge is looking carefully at the barriers and opportunities that exist to enable small and midsize communities to partake in the PEV market and benefit from the economic and environmental advantages of PEVs. In order to gain insight into these challenges and barriers, DOE selected a success story (i.e., Drive Electric Vermont) as the subject of this case study, as the state of Vermont is tied with Detroit, Michigan in having the highest percentage of 2014 (most recent complete data) PEV registrations for cold weather U.S. cities and has seen more than a sixfold increase in charging stations over the last three years. The overall objective of this case study was to use the lessons learned from Drive Electric Vermont to determine what activities are most effective at encouraging acquisitions of PEVs and deployment of charging infrastructure in small to midsize communities, prioritizing and sequencing their implementation, identifying robust means for extrapolation, and applying this understanding to other small to midsize communities across the nation. The Drive Electric Vermont Program was formed in 2012 with a goal of increasing the use of electrified transportation in Vermont through policy development, education and outreach, and infrastructure development. The Drive Electric Vermont Program can be broadly broken into four components: (1) strategic planning/leadership, (2) stakeholder/partnership development, (3) education and outreach, and (4) incentives. The early phases of the program focused heavily on strategic planning, and stakeholder and partnership development, followed by a transition to education and outreach activities, charging infrastructure development, and grant and incentive programs

  9. Complaint studies: Methodological considerations and a result

    DEFF Research Database (Denmark)

    Juhl, Hans Jørn; Poulsen, Carsten Stig; Thøgersen, John

    are developed, ranging from the Rasch model via latent structure analysis with several correlated latent variables to suggestions about a comprehensive framework, combining Fishbein-Ajzen's Theory of Planned Behaviour and latent trait models. The empirical results show that the propensity to complain in Denmark...

  10. Resultados da reabilitação neuropsicológica em paciente com doença de Alzheimer leve Results of neuropsychological rehabilitation in patient with mild Alzheimer's disease - A case study

    Directory of Open Access Journals (Sweden)

    Renata Ávila

    2003-01-01

    Full Text Available Tradicionalmente sempre houve mais grupos de suporte e informação para familiares e cuidadores de pacientes com doença de Alzheimer (DA do que para os próprios pacientes. Entretanto, com o aumento do número de diagnósticos de DA em sua fase inicial, esta realidade está se modificando. Cresce a demanda por tratamento tanto medicamentoso como comportamental para esses pacientes. O presente trabalho tem como objetivo descrever uma experiência de reabilitação neuropsicológica (RN em grupo, e posteriormente individual, com a mesma paciente com DA leve. CGP participou primeiramente de dois grupos de RN com duração de quatro meses cada, e em seguida iniciou RN individual por um período de 22 meses. Na RN foram trabalhados principalmente déficits de memória, linguagem e treinos de atividades de vida diária. Neste período de tratamento, verificou-se alteração positiva de seu escore no MEEM, além de nenhuma função cognitiva ter apresentado deterioração. Este estudo de caso corroborou pesquisas anteriores que apontam efeitos positivos da RN com pacientes com DA leve.Traditionally, Alzheimer's support and information groups have been developed for families and caregivers rather than for the actual patient. However, this reality is changing because of the increase in early AD diagnosis. The demand for medication and behavioral treatment for patients is also increasing. The purpose of this case report is to describe the neuropsychological rehabilitation (NR of a mild AD patient in group and in individual sessions. First, CGP took part in two NR groups each for a 4 month period, and then started individual NR sessions for a 22 month period. In the sessions, memory and language abilities were the focus of the NR as well as the activities of daily living. During this period it was possible to observe positive changes in MMSE score, as will as preservation of other cognitive function scores. This single case study is in agreement of

  11. Roadmaster Roading Contractors Case Study

    Directory of Open Access Journals (Sweden)

    Hazel Taylor

    1999-01-01

    Full Text Available Systems analysis students seldom experience the practical difficulties of the initial investigation into a client’s requirements. They get little chance to practice the skills they need to investigate complex and confused problem situations, or to appreciate the wider organizational issues that can impact on a situation. This teaching case is designed to give students the opportunity to practice and apply investigation skills and to challenge them to consider the wider work environment when considering possible solutions to a problem situation. The case is conducted as a role-play, with students acting as systems analysts and teaching staff role-playing the clients. The students develop a report analyzing the client’s situation based on the issues that arise during the interviews. Feed-back sessions focus on discussing how well the students applied various interviewing strategies previously covered in lectures, and on the wider organizational problems that could impact proposed information system solutions.

  12. Associative visual agnosia: a case study.

    Science.gov (United States)

    Charnallet, A; Carbonnel, S; David, D; Moreaud, O

    2008-01-01

    We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study, an alternative account in the framework of (non abstractive) episodic models of memory.

  13. New results of the extreme multiplicity studies

    CERN Document Server

    Kokoulina, E; Petukhov, Yu; Karpov, A; Kutov, A

    2009-01-01

    Extreme multiplicity studies at 50 GeV in pp interactions are discussed. Preliminary multiplicity distributions at U-70 (IHEP, Protvino) energy have been obtained for more than 20 charged particles. A new elaborated algorithm for the track reconstruction in a drift tube tracker and magnetic spectrometer, has been checked . The collective behavior of secondary particles is manifested in these interactions in the extreme multiplicity region. For the first time the ring events in pp interactions have been observed in this region. A possibility of detecting the Bose-Einstein condensation detection is discussed.

  14. Mead acid (20:3n-9) and n-3 polyunsaturated fatty acids are not associated with risk of posterior longitudinal ligament ossification: results of a case-control study.

    Science.gov (United States)

    Hamazaki, Kei; Kawaguchi, Yoshiharu; Nakano, Masato; Yasuda, Taketoshi; Seki, Shoji; Hori, Takeshi; Hamazaki, Tomohito; Kimura, Tomoatsu

    2015-05-01

    Ossification of the posterior longitudinal ligament (OPLL) involves the replacement of ligamentous tissue with ectopic bone. Although genetics and heritability appear to be involved in the development of OPLL, its pathogenesis remains to be elucidated. Given previous findings that 5,8,11-eicosatrienoic acid [20:3n-9, Mead acid (MA)] has depressive effects on osteoblastic activity and anti-angiogenic effects, and that n-3 polyunsaturated fatty acids (PUFAs) have a preventive effect on heterotopic ossification, we hypothesized that both fatty acids would be involved in OPLL development. To examine the biological significance of these and other fatty acids in OPLL, we conducted this case-control study involving 106 patients with cervical OPLL and 109 age matched controls. Fatty acid composition was determined from plasma samples by gas chromatography. Associations between fatty acid levels and incident OPLL were evaluated by logistic regression. Contrary to our expectations, we found no significant differences between patients and controls in the levels of MA or n-3 PUFAs (e.g., eicosapentaenoic acid and docosahexaenoic acid). Logistic regression analysis did not reveal any associations with OPLL risk for MA or n-3 PUFAs. In conclusion, no potential role was found for MA or n-3 PUFAs in ectopic bone formation in the spinal canal. PMID:25669698

  15. Academic Planning: Four Institutional Case Studies.

    Science.gov (United States)

    Kieft, Raymond N.

    As part of a project studying intrainstitutional planning, management, and evaluation, four case studies were undertaken in 1976 of academic planning at Villa Maria College, Kansas City Metropolitan Community College District, West Virginia University, and Western Washington University. The case studies were part of an ongoing project, the…

  16. Liverpool Telecare Pilot: case studies

    Directory of Open Access Journals (Sweden)

    Nigel Barnes

    2006-09-01

    Full Text Available Telecare services use information and communications technology (ICT to support the provision of care to people in their own homes. This paper describes a pilot telecare service employed by Liverpool (UK City Council to support a sample of their frail and elderly social services users. The pilot has been running for over two years and has been deployed for 21 individuals in Liverpool. In this paper we present the pilot system and provide real example cases which help to illustrate the benefits of such a system.

  17. Results of the NFIRAOS RTC trade study

    Science.gov (United States)

    Véran, Jean-Pierre; Boyer, Corinne; Ellerbroek, Brent L.; Gilles, Luc; Herriot, Glen; Kerley, Daniel A.; Ljusic, Zoran; McVeigh, Eric A.; Prior, Robert; Smith, Malcolm; Wang, Lianqi

    2014-07-01

    With two large deformable mirrors with a total of more than 7000 actuators that need to be driven from the measurements of six 60x60 LGS WFSs (total 1.23Mpixels) at 800Hz with a latency of less than one frame, NFIRAOS presents an interesting real-time computing challenge. This paper reports on a recent trade study to evaluate which current technology could meet this challenge, with the plan to select a baseline architecture by the beginning of NFIRAOS construction in 2014. We have evaluated a number of architectures, ranging from very specialized layouts with custom boards to more generic architectures made from commercial off-the-shelf units (CPUs with or without accelerator boards). For each architecture, we have found the most suitable algorithm, mapped it onto the hardware and evaluated the performance through benchmarking whenever possible. We have evaluated a large number of criteria, including cost, power consumption, reliability and flexibility, and proceeded with scoring each architecture based on these criteria. We have found that, with today's technology, the NFIRAOS requirements are well within reach of off-the-shelf commercial hardware running a parallel implementation of the straightforward matrix-vector multiply (MVM) algorithm for wave-front reconstruction. Even accelerators such as GPUs and Xeon Phis are no longer necessary. Indeed, we have found that the entire NFIRAOS RTC can be handled by seven 2U high-end PC-servers using 10GbE connectivity. Accelerators are only required for the off-line process of updating the matrix control matrix every ~10s, as observing conditions change.

  18. Unexplained False Negative Results in Noninvasive Prenatal Testing: Two Cases Involving Trisomies 13 and 18

    Directory of Open Access Journals (Sweden)

    R. Hochstenbach

    2015-01-01

    Full Text Available Noninvasive prenatal testing (NIPT validation studies show high sensitivity and specificity for detection of trisomies 13, 18, and 21. False negative cases have rarely been reported. We describe a false negative case of trisomy 13 and another of trisomy 18 in which NIPT was commercially marketed directly to the clinician. Both cases came to our attention because a fetal anatomy scan at 20 weeks of gestation revealed multiple anomalies. Karyotyping of cultured amniocytes showed nonmosaic trisomies 13 and 18, respectively. Cytogenetic investigation of cytotrophoblast cells from multiple placental biopsies showed a low proportion of nontrisomic cells in each case, but this was considered too small for explaining the false negative NIPT result. The discordant results also could not be explained by early gestational age, elevated maternal weight, a vanishing twin, or suboptimal storage or transport of samples. The root cause of the discrepancies could, therefore, not be identified. The couples involved experienced difficulties in accepting the unexpected and late-adverse outcome of their pregnancy. We recommend that all parties involved in caring for couples who choose NIPT should collaborate to clarify false negative results in order to unravel possible biological causes and to improve the process of patient care from initial counseling to communication of the result.

  19. Russian Media Educators: Case Studies Portraits

    Directory of Open Access Journals (Sweden)

    Alexander Fedorov

    2013-01-01

    Full Text Available This article is devoted to case studies of the media education works of some well knowns Russian media educators. The analysis of media educational work of the famous Russian media educators leads us to the conclusion that media education in Russia is developing, building on the synthesis of the aesthetic, socio-cultural, and practical concepts, with a focus on the development of media competence of the audience, mainly school and youth. The enthusiasts of media education, even devoid of substantial public support for its innovative projects, achieve significant and meaningful results.

  20. A Codesign Case Study in Computer Graphics

    DEFF Research Database (Denmark)

    Brage, Jens P.; Madsen, Jan

    1994-01-01

    The paper describes a codesign case study where a computer graphics application is examined with the intention to speed up its execution. The application is specified as a C program, and is characterized by the lack of a simple compute-intensive kernel. The hardware/software partitioning is based...... on information obtained from software profiling and the resulting design is validated through cosimulation. A locally developed interface model, Merlin, is used as the basis for co-simulation. The achieved speed-up is estimated based on an analysis of profile information....

  1. Metrology in Pharmaceutical Industry - A Case Study

    Science.gov (United States)

    Yuvamoto, Priscila D.; Fermam, Ricardo K. S.; Nascimento, Elizabeth S.

    2016-07-01

    Metrology is recognized by improving production process, increasing the productivity, giving more reliability to the measurements and consequently, it impacts in the economy of a country. Pharmaceutical area developed GMP (Good Manufacture Practice) requeriments, with no introduction of metrological concepts. However, due to Nanomedicines, it is expected this approach and the consequent positive results. The aim of this work is to verify the level of metrology implementation in a Brazilian pharmaceutical industry, using a case study. The purpose is a better mutual comprehension by both areas, acting together and governmental support to robustness of Brazilian pharmaceutical area.

  2. Midterm results of endovascular treatment of iliac artery lesions: analysis of 59 cases

    Directory of Open Access Journals (Sweden)

    Leonardo Ghizoni Bez

    2013-06-01

    Full Text Available BACKGROUND: Endovascular treatment of peripheral arterial occlusive disease has become increasingly frequent in the past few years. Because it is a less invasive procedure, lower morbidity and mortality rates are associated with this form of treatment. OBJECTIVES: To describe the endovascular procedures performed in iliac arteries for the treatment of peripheral arterial occlusive disease. METHODS: This retrospective study assesses 59 cases of iliac artery angioplasty performed according to a specific protocol from January 2004 to February 2010. RESULTS: Mean age of patients was 62 years (minimum: 42, maximum: 89. Thirty seven were male (62.72% and 22 female (37.28%. The main indications for treatment were moderate to severe intermittent claudication in 30 cases (50.84% and rest pain or trophic lesions (critical ischemia in 29 cases (49.15%. Postoperative follow-up included ankle-brachial index measurements and a duplex ultrasound at 30 days, 3 months, 6 months, 12 months, and every 6 months thereafter. Minimum follow-up time was 3 months, and maximum, 72 months (6 years, with primary and secondary patency rates of 91.37 and 94.82%, respectively. CONCLUSIONS: The results of this case series, combined with literature review results, allow to conclude that the endovascular approach is an effective and safe option to treat peripheral arterial occlusive disease in iliac arteries.

  3. Case studies in Bayesian microbial risk assessments

    Directory of Open Access Journals (Sweden)

    Turner Joanne

    2009-12-01

    Full Text Available Abstract Background The quantification of uncertainty and variability is a key component of quantitative risk analysis. Recent advances in Bayesian statistics make it ideal for integrating multiple sources of information, of different types and quality, and providing a realistic estimate of the combined uncertainty in the final risk estimates. Methods We present two case studies related to foodborne microbial risks. In the first, we combine models to describe the sequence of events resulting in illness from consumption of milk contaminated with VTEC O157. We used Monte Carlo simulation to propagate uncertainty in some of the inputs to computer models describing the farm and pasteurisation process. Resulting simulated contamination levels were then assigned to consumption events from a dietary survey. Finally we accounted for uncertainty in the dose-response relationship and uncertainty due to limited incidence data to derive uncertainty about yearly incidences of illness in young children. Options for altering the risk were considered by running the model with different hypothetical policy-driven exposure scenarios. In the second case study we illustrate an efficient Bayesian sensitivity analysis for identifying the most important parameters of a complex computer code that simulated VTEC O157 prevalence within a managed dairy herd. This was carried out in 2 stages, first to screen out the unimportant inputs, then to perform a more detailed analysis on the remaining inputs. The method works by building a Bayesian statistical approximation to the computer code using a number of known code input/output pairs (training runs. Results We estimated that the expected total number of children aged 1.5-4.5 who become ill due to VTEC O157 in milk is 8.6 per year, with 95% uncertainty interval (0,11.5. The most extreme policy we considered was banning on-farm pasteurisation of milk, which reduced the estimate to 6.4 with 95% interval (0,11. In the second

  4. Five case studies of multifamily weatherization programs

    Energy Technology Data Exchange (ETDEWEB)

    Kinney, L; Wilson, T.; Lewis, G. [Synertech Systems Corp. (United States); MacDonald, M. [Oak Ridge National Lab., TN (United States)

    1997-12-31

    The multifamily case studies that are the subject of this report were conducted to provide a better understanding of the approach taken by program operators in weatherizing large buildings. Because of significant variations in building construction and energy systems across the country, five states were selected based on their high level of multifamily weatherization. This report summarizes findings from case studies conducted by multifamily weatherization operations in five cities. The case studies were conducted between January and November 1994. Each of the case studies involved extensive interviews with the staff of weatherization subgrantees conducting multifamily weatherization, the inspection of 4 to 12 buildings weatherized between 1991 and 1993, and the analysis of savings and costs. The case studies focused on innovative techniques which appear to work well.

  5. Regional case studies--Africa.

    Science.gov (United States)

    Prentice, Andrew M

    2009-01-01

    Africa is the final continent to be affected by the nutrition transition and, as elsewhere, is characterized by the paradoxical coexistence of malnutrition and obesity. Several features of the obesity epidemic in Africa mirror those in other emerging nations: it penetrates the richer nations and urban areas first with a strong urban- rural gradient; initially it affects the wealthy, but later there is a demographic switch as obesity becomes a condition more associated with poverty, and it shares many of the same drivers related to the increasing affordability of highly refined oils and carbohydrates, and a move away from subsistence farm work and towards sedentary lifestyles. Africa also has some characteristics of the obesity epidemic that stand out from other regions such as: (1) excepting some areas of the Pacific, Africa is probably the only region in which obesity (especially among women) is viewed culturally as a positive and desirable trait, leading to major gender differences in obesity rates in many countries; (2) most of Africa has very low rates of obesity in children, and to date African obesity is mostly an adult syndrome; (3) Africans seem genetically prone to higher rates of diabetes and hypertension in association with obesity than Caucasians, but seem to be relatively protected from dislipidemias; (4) the case-specific deaths and disabilities from diabetes and hypertension in Africa are very high due to the paucity of health services and the strain that the 'double burden' of disease places on health systems.

  6. Leishmaniasis in dogs: Case study

    Directory of Open Access Journals (Sweden)

    Aleksić Jelena

    2009-01-01

    Full Text Available The paper presents a case of leishmaniasis in a 2.5-month-old dog imported from France. The clinical examination established a generally poor state of health, expressed cachexia, atrophy of the temporal musculature, weakness of movement, as well as abnormally long and brittle nails. There was also hyperkeratosis of the nose tip and paws. A histological examination of biopsy sections of the altered skin parts showed inflammatory changes in the area of the dermis, together with infiltration of macrophages and a smaller number of lymphocytes, plasmocytes and neutrophil granulocytes in the area around the sebaceous glands and hair follicles. The determined changes correspond to superficial dermatitis. Edema followed by partial degeneration of connective-tissue fibers is observed in connective tissue. A smaller number of intracellular parasitic forms was established in mononuclear cells. A smaller number of oval amastigotes with round dark red nucleis were observed in sections stained using the Gimza method in the cytoplasm of macrophages located in the dermis, but also extracellularly. It was concluded that the dog was diseased with leishmaniasis on the grounds of the clinical picture and the microscopic findings.

  7. Recurrent hydramnios as a result of fetal Bartter′s syndrome (a case report.

    Directory of Open Access Journals (Sweden)

    Shah M

    1991-04-01

    Full Text Available Bartter′s syndrome has been reported as a rare case of hydramnios. A unique case of recurrent hydramnios in pregnancy as a result of fetal Bartter′s syndrome on both occasions is presented.

  8. The use of case studies in teaching undergraduate neuroscience.

    Science.gov (United States)

    Meil, William M

    2007-01-01

    Case studies have been the cornerstone of many discoveries in neurology and continue to be an indispensable source of knowledge. Attaching a name, face, and story to the study of neurological disorders makes them more "real" and memorable. This article describes the value of the case study methodology and its advantages as a pedagogical approach. It also illustrates how the seminal case of H.M. can be used to highlight the advantages and disadvantages of the case study methodology. Three exercises are described for incorporating case studies into neuroscience courses. The first exercise requires students to conduct a literature review regarding their assigned case and then design an experiment to address a lingering question regarding that neurological disorder. Survey results of 90 students provide quantitative and qualitative support for this approach. The vast majority of students indicated this exercise was a valuable learning experience; sparked interest in the topic and in biopsychology; increased their knowledge and stimulated critical thinking. The second exercise discusses how students might conduct their own case studies. The third exercise emphasizes the use of case studies as a platform to examine competing hypotheses regarding neurological conditions and their treatment. A table listing case studies appropriate for undergraduate neuroscience courses is included. Cases are categorized by the type of neurological disorder and notes regarding the nature of and content of each case are provided. PMID:23493154

  9. US country studies program: Results from mitigation studies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This paper describes the U.S. Country Studies Program which was implemented to support the principles and objectives of the Framework Convention on Climate Change (FCCC). There were three principle objectives in this program: to enhance capabilities to conduct climate change assessments, prepare action plans, and implement technology projects; to help establish a process for developing and implementing national policies and measures; to support principles and objective of the FCCC. As a result, 55 countries are completing studies, more than 2000 analysts engaged in the studies have been trained, and there is a much broader understanding and support for climate change concerns. The article describes experiences of some countries, and general observations and conclusions which are broadly seperated into developed countries and those with economies in transition.

  10. Rebranding: a Case Study Approach

    OpenAIRE

    Size, Maria, (Thesis)

    2005-01-01

    The primary objective of this study is to explore how and why companies implement rebranding campaigns. The study stemmed from a realisation by the author that the area of rebranding is very much under-researched academically although anecdotal evidence indicates and increase in the occurrence of the phenomenon in recent years. Therefore the purpose of this research is to add to the insufficient body of literature on rebranding through exploring it from a corporate perspective. The two chapte...

  11. The risk of acute liver injury among users of antibiotic medications in the protect project: The results of a nested case-control study using european outpatient healthcare data

    NARCIS (Netherlands)

    Brauer, Ruth; Douglas, Ian; Rodriguez, Luis Alberto Garcia; Bate, Andrew; Smeeth, Liam; Reynolds, Robert; Klungel, Olaf; Ruigomez, Ana

    2014-01-01

    Background: The estimated incidence of antibiotic induced acute liver injury (ALI) varies widely, depending on the case definition and source population used. Objectives: We aimed to compare the risk of ALI associated with exposure to any type of antibiotic in a Spanish and United Kingdom (UK) datab

  12. Outage management: A case study

    International Nuclear Information System (INIS)

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study

  13. Outage management: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Barriere, M.T. (Brookhaven National Lab., Upton, NY (United States)); Roberts, K.H. (California Univ., Berkeley, CA (United States). Walter A. Haas School of Business)

    1992-01-01

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study.

  14. Outage management: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Barriere, M.T. [Brookhaven National Lab., Upton, NY (United States); Roberts, K.H. [California Univ., Berkeley, CA (United States). Walter A. Haas School of Business

    1992-09-01

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission`s (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study.

  15. Case Study Methodology and Homelessness Research

    Directory of Open Access Journals (Sweden)

    Jill Pable

    2013-10-01

    Full Text Available This paper describes the potential suitability of case study methodology for inquiry with the homeless population. It references a research study that uses case study research method to build theory. This study's topic is the lived experience of destitute individuals who reside in homeless shelters, and explores the homeless shelter built environment's potential influence on resident satisfaction and recovery. Case study methodology may be appropriate because it explores real-life contextual issues that characterize homelessness and can also accommodate the wide range of homeless person demographics that make this group difficult to study in a generalized fashion. Further, case study method accommodates the need within research in this area to understand individualized treatments as a potential solution for homelessness.

  16. Undergraduate research: a case study

    NARCIS (Netherlands)

    Koppelman, Herman; Dijk, van Betsy; Hoeven, van der Gerrit

    2011-01-01

    This paper describes a one semester research course for undergraduates of computing programs. Students formulate a research proposal, conduct research and write a full paper. They present the results at a one-day student conference. On the one hand we offer the students a lot of structure and suppor

  17. Case Study on Quality Education

    Science.gov (United States)

    Habib, Zahida

    2011-01-01

    Quality of Education, especially at Primary level, is an important issue to be discussed at the International Forum. This study highlights the quality of primary education through a comparison of the quality of Community Model Schools and Govt. Girls Primary Schools in Pakistan. Community Model Schools were established under Girls Primary…

  18. Associative Visual Agnosia: A Case Study

    Directory of Open Access Journals (Sweden)

    A. Charnallet

    2008-01-01

    Full Text Available We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study [1], an alternative account in the framework of (non abstractive episodic models of memory [4].

  19. Release and deployment at Planon: a case study

    NARCIS (Netherlands)

    Jansen, R.L.; Ballintijn, G.C.; Brinkkemper, S.

    2005-01-01

    This case study report describes the research results of a case study at Planon into the processes of development, release, and deployment. The research was done to document the release and deployment processes at Planon, to uncover strengths and weaknesses in these processes, and to compare Planon

  20. Marketing-Indonesia case study

    OpenAIRE

    Kurniawan, Iwan; Roshetko, James M.

    2007-01-01

    The purpose of research are (1) to identify the potential VAF species or products for Nanggung Farmers; (2) identify market channels & marketing problems; (3) enhances farmers' understanding of market mechanism; and (4) identify opportunities to improve the quantity & quality of VAF. The study was conducted on Sept-Oct 2006. Data and information are collected through Focus Group Discussion (FGD) in each village that attended both men and women. LTRA-5 (Agroforestry and Sustainable Vegetabl...

  1. Environmental contracting: a case study

    OpenAIRE

    Kubiak, Joseph C.

    1994-01-01

    Approved for public release, distribution unlimited The end of cold war levels of defense expenditures has promoted the reduction in the number of defense-related companies, creating potential monopolistic economic scenarios for defense procurement. This thesis studies one methodology to deal with these scenarios, based on the Baron-Myerson monopolist regulation mechanisms. The Baron-Myerson mechanism provides a tool to regulate monopolists when their costs are unknown or cannot be measure...

  2. Transmission electron microscopy of ameloblastoma: A study on six cases

    OpenAIRE

    Chawla, Rajeshwar; Ramalingam, Karthikeyan; Sarkar, Amitabha; Muddiah, Savita

    2013-01-01

    Background: Ameloblastoma is a rare, benign tumor of odontogenic epithelium, but with an aggressive clinical behavior. Aim: The present study aims to assess the ultramicroscopic features of the epithelial and connective tissue components of ameloblastoma. Materials and Methods: Six cases of ameloblastoma were subjected to electron microscopy. They included three cases of follicular type and three cases of plexiform type. Results: The study reveals that the ameloblastoma contains the full comp...

  3. Unmasking Cleckley's psychopath: assessing historical case studies.

    Science.gov (United States)

    DeShong, Hilary L; Helle, Ashley C; Mullins-Sweatt, Stephanie N

    2016-05-01

    The current study investigated original case descriptions of psychopathy (Cleckley, 1941) in relation to current conceptualizations and general personality traits. Attorneys, forensic psychologists and clinical faculty members completed ratings of psychopathy and personality after reading vignettes based on Cleckley's descriptions of a psychopath. The results suggest that professionals' ratings are consistent with current conceptualizations of psychopathy. Furthermore, the five-factor model (FFM) personality traits of the vignettes aligned with the current literature on the FFM and psychopathy (i.e. low neuroticism, conscientiousness and agreeableness). The results further supported that a general trait model, like the FFM, may be well suited to describe the underlying personality traits of psychopathy. Gender differences were also examined. PMID:26931520

  4. Ownership and Control Structures: A Case Study

    OpenAIRE

    Apostolov, Mico

    2015-01-01

    This is a study on separation of ownership and control in Southeast Europe, and in particular it is a case study of Macedonia. For structured analysis of this case study we use the World Bank Microdata Library, specifically the Enterprise Surveys which contains firm-level data of a representative sample of economies private sectors. What we are interested in are the ties of ownership and control and whether such linkages contribute to the development of domestic firms and the overall ec...

  5. Social Architecture: An Emergency Management Case Study

    Directory of Open Access Journals (Sweden)

    Asif Qumer Gill

    2015-03-01

    Full Text Available Emergency management agencies are progressively using social media for the sourcing and distribution of disaster information. Emergency management agencies are often unsure as to how to best identify and assess social media concerns (e.g. information security, trust which must be addressed to develop a social media-enabled disaster information management environment. This paper adopts the Social Architecture Viewpoint Assessment (SAVA framework for identifying and assessing social media concerns from four different viewpoints: IT, Value, Resource and Management. This paper demonstrates the use of the SAVA framework in the context of an in-depth empirical case study of an Australian emergency management agency. The results of this study indicate that the SAVA framework is useful for emergency information management managers in identifying and assessing social media concerns.

  6. Commercializing Emerging Renewable Energy: A Case Study

    Directory of Open Access Journals (Sweden)

    Matti Lehtovaara

    2012-12-01

    Full Text Available A broad scientific consensus exists that the global climate is changing. The Earth’s surface temperature could rise significantly over the next few decades, leading to us witnessing an entirely new and unknown planet. Improved energy efficiency, decreasing use of fossil fuels and wide diffusion of various renewable energy sources are among the focal measures to limit global warming to a sustainable level. The objective of this study is to analyse how renewable energy, such as wind power and bioenergy, could be efficiently commercialized. The evaluation is based on a case study and expert analyses exploiting lateral and parallel thinking methods, and group decision support systems tools. The results reveal that some of the generated ideas are ready for implementation to commercialize renewable energy, whereas others still require technical and commercial development and improvements before maturity.

  7. INTERIORITY - a prefab case study

    DEFF Research Database (Denmark)

    Hvejsel, Marie Frier

    been motivated by the particular hypothesis that an introduction of the notion of interiority, as an ability of the spatial envelope itself to address the sensuous scale of furniture, unfolds a particular dual critical potential signifying our experience of domestic architectural quality: On the one...... an interrelation of the functional and emotional dimensions of furniture and envelope as form, with the necessary economy and logic of construction, can be developed as a critical architctural theory for transforming the technical and economical elements of construction into experiences of interiority within...... of furnishing ‘gestures’ requiring of the envelope itself to guide, reveal, cover, caress and embrace us. These ‘gestures’ unite function and emotion by describing at once a physical movement and a feeling which is intrinsic of the spatial envelope itself. - The explanatory level has resulted in the development...

  8. Music in context : Four case studies

    NARCIS (Netherlands)

    Randwijck, R.J.C. van

    2008-01-01

    In his thesis entitled “Music in Context. Four Case Studies”, R.J.C. van Randwijck investigates the context in which music has been created. It is a search in Four Case Studies, approaching four pieces of music from the context in which they were written in order to understand their meaning. The inv

  9. Case studies of steel structure failures

    Directory of Open Access Journals (Sweden)

    P. Bernasovský

    2010-01-01

    Full Text Available The contribution deals with some case studies of steel structure failures, which happened in Slovakia a few years ago. Features of cracking are illustrated on real cases of breakdowns in the transmission gas pipelines, at the cement works and in the petrochemical indus-try. All failures were caused by an incorrect technical approach. Possible remedial measures are proposed.

  10. Abbreviated Case Studies in Organizational Communication

    Science.gov (United States)

    Wanguri, Deloris McGee

    2005-01-01

    The cases contained within organizational communication texts are generally two to three pages, often followed by questions. These case studies are certainly useful. They generally describe events in the present, provide some type of organizational context, include first-hand data, include a record of what people say and think, develop a…

  11. Mining Product Data Models: A Case Study

    OpenAIRE

    Cristina-Claudia DOLEAN

    2014-01-01

    This paper presents two case studies used to prove the validity of some data-flow mining algorithms. We proposed the data-flow mining algorithms because most part of mining algorithms focuses on the control-flow perspective. First case study uses event logs generated by an ERP system (Navision) after we set several trackers on the data elements needed in the process analyzed; while the second case study uses the event logs generated by YAWL system. We offered a general solution of data-flow m...

  12. Case study on printed matter

    DEFF Research Database (Denmark)

    Introduction Existing product Life Cycle Assessments (LCA’s) on offset printed matter all point at paper as the overall dominating contributor to the impacts from the life-cycle of this category of products. This dominating role of paper is primarily founded in the energy-related impact categories...... global warming, acidification and nutrification. The studies focus on energy consumption including the emissions and impact categories related to energy. The chemical-related impact categories comprising ecotoxicity and human toxicity are not included at all or only to a limited degree. In this paper we...... include these chemical-related impact categories by making use of some of the newest knowledge about emissions from the production at the printing industry combined with knowledge about the composition of the printing materials used during the production of offset printed matter. This paper is based...

  13. Case study in professionally-oriented training

    Directory of Open Access Journals (Sweden)

    Valitov Shamil M.

    2016-01-01

    Full Text Available Modern educational technologies are based on competence approach and focus on the future professional activity. Case study is one of the most significant technologies in modern higher education. The basic concepts used in the case study method are a “situation” and an “analysis”, as well as their derivative - “analysis of the situation”. The case study method of is one of the best tools for gaining experience, as it investigates practical situations that occur in managerial job. It combines theoretical knowledge with the analysis of the actual practical experience in accordance with a major. Doing case studies students read the description of the situation and offer divergent projects of managerial decisions that could be used by real managers dealing with the problem posed by the case study author. Answers to the questions posed in the case description are not given, as a rule, since the main purpose in the case analysis is to organize a discussion in the classroom or provoke speculations of those who do the self-study.

  14. Pharmacogenomics Bias - Systematic distortion of study results by genetic heterogeneity

    Directory of Open Access Journals (Sweden)

    Zietemann, Vera

    2008-04-01

    Full Text Available Background: Decision analyses of drug treatments in chronic diseases require modeling the progression of disease and treatment response beyond the time horizon of clinical or epidemiological studies. In many such models, progression and drug effect have been applied uniformly to all patients; heterogeneity in progression, including pharmacogenomic effects, has been ignored. Objective: We sought to systematically evaluate the existence, direction and relative magnitude of a pharmacogenomics bias (PGX-Bias resulting from failure to adjust for genetic heterogeneity in both treatment response (HT and heterogeneity in progression of disease (HP in decision-analytic studies based on clinical study data. Methods: We performed a systematic literature search in electronic databases for studies regarding the effect of genetic heterogeneity on the validity of study results. Included studies have been summarized in evidence tables. In the case of lacking evidence from published studies we sought to perform our own simulation considering both HT and HP. We constructed two simple Markov models with three basic health states (early-stage disease, late-stage disease, dead, one adjusting and the other not adjusting for genetic heterogeneity. Adjustment was done by creating different disease states for presence (G+ and absence (G- of a dichotomous genetic factor. We compared the life expectancy gains attributable to treatment resulting from both models and defined pharmacogenomics bias as percent deviation of treatment-related life expectancy gains in the unadjusted model from those in the adjusted model. We calculated the bias as a function of underlying model parameters to create generic results. We then applied our model to lipid-lowering therapy with pravastatin in patients with coronary atherosclerosis, incorporating the influence of two TaqIB polymorphism variants (B1 and B2 on progression and drug efficacy as reported in the DNA substudy of the REGRESS

  15. Results of Measurement of Natural Radioactivity of Sediments – Gulfs of Vlora and Dures - Albania [Case Study: Natural Radioactivity of Coastal Sediments as “Tracer” in Dynamic Sedimentology

    International Nuclear Information System (INIS)

    Natural radiometric survey of the sediments of sea bottom provided some qualitative sediment transport features, characteristics and parameters similar with those obtained with radiotracers, in particular the resultant direction and mechanism of sediment transport were made evident. This simple and low cost technique can be used for sediment transport studies as complementary to other techniques. The radiometric survey of the sediments of sea bottom and beaches in the gulfs of Vlora and Durres has provided the following major conclusions: Vlora 1. Waves coming from the west move sends normal to the beach line. The influence of waves of this sector is up to depth 15 m, where is the boundary between sand and silt. Durres 1. There was not any visible granulometric selection of sea bottom sediments in the gulf of Durres. 2. There was an indication of sediment transport trend from south to the north of the gulf under the influence of waves coming from the south sector. 3. There was evidence of silting process, in particular in the first part of the navigation channel near the harbor

  16. Results of the Study of Mutagenic Effects of Microbial Polysaccharides

    Directory of Open Access Journals (Sweden)

    Natalya A. Sidorova

    2016-06-01

    Full Text Available The article presents the results of a study of mutagenic effects of Pseudomonas alcaligenеs polysaccharides. Pseudomonas genus – non-fermentative ubiquitous bacteria, having specific metabolic cycles and unique physical, chemical and biological properties was used as a producer of natural exopolysaccharides. In an experiment using the Ames test, three variants of test compounds were studied: 1. a compound of the Pseudomonas alcaligenes biofilm, 2. exopolysaccharide matrix and the microorganism cell wall compound, and 3. actually the microbial exopolysaccharide. In all cases the lack of mutagen action of polysaccharides of Pseudomonas alcaligenes is proved that make them perspective for use as nanomaterials of new generation – alternative wound coverings.

  17. Energy Audit: A Case Study

    Directory of Open Access Journals (Sweden)

    Sanjay Kumar

    2013-06-01

    Full Text Available This India is the Fifth largest producer of Electricalenergy in the world. Despite such achievements the gapbetween demand and supply of electrical energy is increasingevery year and power sector is highly capital – intensive. Thusthe deficit in installed capacity was nearly 10000MWper year.So the gap between demand and supply is continuouslyincreasing day by day. An energy audit is a study of a plant orfacility to determine how and where energy is used and toidentify methods for energy savings. The opportunities lie inthe use of existing renewable energy technologies, greaterefforts at energy efficiency and the dissemination of thesetechnologies and options. This thesis provides an overview of ageneral energy conservation measures (ECMs that can becommonly recommended for NIT Hamirpur. It should be notedthat the Energy auidut presented in this paper does not pretendto be exhaustive nor comprehensive. It provides merely toindicate some of the options that energy auditor can considerwhen performing an analysis of this institute. Energyconservation and exploration of new energy avenues are thewell accepted solution to fulfil the demand in future. The totalcost of energy plays a vital role in determining the product costof a commodity. Therefore the identification of potential energysavings and implementation for a given institutional facility isunimportant to ensure its competitive advantage over otherinstitute. This paper work presents such energy saving methodsin a methodological approach, experienced during a detailedenergy audit of NIT Hamirpur.

  18. Antiphospholipid syndrome: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Davies, T. [Royal Adelaide Hospital, Adelaide, SA (Australia). Department of Nuclear Medicine

    1998-03-01

    Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient``s high risk of strokes and hemorrhaging prompted investigation by a {sup 99}mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome.

  19. Small power systems study. Volume. Study results. Technical summary report

    Energy Technology Data Exchange (ETDEWEB)

    Sitney, L.R.

    1978-05-31

    The Division of Solar Technology of the Department of Energy is currently examining the market potential of a number of dispersed solar energy systems, including the small (less than or equal to 10 MW/sub e/) solar thermal power system. Small fossil-fueled generating units in the United States utility system, (i.e., investor-owned, municipal, and cooperatives) have a current capacity of approximately 8000 MW/sub e/ or about 1.5 percent of the total US electrical capacity, and provide a large potential market for small solar thermal power systems. The Small Power Systems Study has as its objective the determination of conditions under which small (less than or equal to 10 MW/sub e/) solar thermal power units can provide cost-effective electrical power to a variety of users. Potential users, in addition to the utility systems; include Department of Defense installations and applications, remote mining and/or lumbering operations, and other industrial power systems with and without cogeneration. The first year's results on the Small Power Systems Study are summarized. The data base used and the breakeven cost analysis are discussed. Information on both small (less than or equal to 10 MW/sub e/) generating units and the utility systems using them is presented as well as data on fossil fuel costs, solar plant costs, and solar insolation values. The results of a survey of Department of Defense (DOD) worldwide electrical generating capacity at its military bases and on a potential DOD application are presented. Information on a potential small solar power system experiment in the interior of Alaska is given, and a limited amount of information on a remote application which would provide power or a large open pit copper mine is presented. Volume II of this Technical Summary Report contains an inventory, by state, of the small (less than or equal to 10 MW/sub e/) generating units in the US utility system. (WHK)

  20. Logistics opportunity costs: A mining case study

    Directory of Open Access Journals (Sweden)

    Leani van Jaarsveld

    2013-05-01

    Full Text Available This study highlighted the importance of determining the impact that an ineffective mode of transport has on a firm’s transportation model and costs. The main focus of this study was to determine the logistics opportunity costs of using road transport within a mining firm. A case study approach was followed, as the investigation aimed to analyse a complex problem experienced by one company and present it in an easily understandable format. From the results of this study, it was apparent that the logistics opportunity costs associated with the mode of transport was substantial. This highlighted the need for firms to revise their choice of transport mode on a regular basis, as it has a major impact not only on their transportation costs, but also on their inventory holding and carbon emissions. The results also have implications for South Africa’s only freight railway, Transnet Freight Rail, which should not only focus on expanding its existing capacity, but also on improving its customer service delivery whilst containing tariff increases.

  1. Biometric Calculation and Refractive Results. A Study of 250 Cases of Patients Operated for Cataract Cálculo biométrico y resultados refractivos. Estudio de 250 casos operados de catarata

    Directory of Open Access Journals (Sweden)

    Inés Benita Zamora Galindo

    2012-02-01

    Full Text Available

    Fundamento: el implante de lentes intraoculares en la cirugía de catarata significa un avance en la corrección refractiva de la afaquia. Pero sin el estudio previo a la cirugía y el correcto cálculo de la lente intraocular, los resultados no serían satisfactorios. Objetivo: evaluar el cálculo biométrico y la refracción posquirúrgica de pacientes operados de cataratas. Metodos: estudio descriptivo realizado en el Centro de Oftalmología del Estado de Anzoátegui, Venezuela, que incluyó 250 pacientes sometidos a cirugía de catarata, a quienes previamente se les realizó refracción, queratometría, biometría y cálculo de lente intraocular. Después de la cirugía se determinó: refracción esperada por el cálculo biométrico, error refractivo posoperatorio, agudeza visual posquirúrgica sin corrección y con corrección. Resultados: predominó el sexo femenino y el grupo de edad entre 60 y 69 años. El valor más registrado de la queratometría  osciló de 43 a 44 dioptrías. El valor de la longitud axial más destacado fue de 22 a 24 mm. Las lentes intraoculares más usadas fueron de 16 a 20 dioptrías y las de 21 a 25 dioptrías. El mayor por ciento de la refracción esperada estuvo en el grupo de 0,00 a 0, 50. El error refractivo que predominó fue el de 0,50 a 1,00. En la refracción realizada al mes de la cirugía, sin cristales, más de la mitad de los pacientes obtuvo visiones entre 20/30 y 20/25. Conclusiones: se demostró la efectividad del cálculo de la lente intraocular previo a la cirugía de catarata.

    Background: the implantation of intraocular lenses in cataract surgery represents a step forward in refractive correction of aphakia. Nevertheless, without a study prior to surgery and the correct calculation of the intraocular lens, the results would not be satisfactory.

  2. Towards More Case Study Research in Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Tom Duxbury

    2012-03-01

    Full Text Available Entrepreneurship as an emerging discipline has made good strides, but according to some, has fallen short of bringing its theory and literature up to the standards of others in the management sciences. Rich with the descriptive detail needed for insightful theory building in entrepreneurship, scholars have called for more case study research, particularly those incorporating non-retrospective and longitudinal observations. At the same time however, it has become rare to find such research published in A-level journals dedicated to entrepreneurship. A survey presented here of major entrepreneurship journals over the past six years revealed a publication rate of only 3% using the case study method. This presents a major impediment for developing fresh research in this field based upon the study of real cases. The author explores how the case study method has been applied to entrepreneurship research and provides recommendations for improved publication rates.

  3. Does Pregnancy-Associated Breast Cancer Imply a Worse Prognosis? A Matched Case-Case Study

    Science.gov (United States)

    Dimitrakakis, Constantine; Zagouri, Flora; Tsigginou, Alexandra; Marinopoulos, Spyros; Sergentanis, Theodoros N.; Keramopoulos, Antonis; Zografos, George C.; Ampela, Konstantina; Mpaltas, Dimosthenis; Papadimitriou, Christos; Dimopoulos, Meletios-Athanassios; Antsaklis, Aris

    2013-01-01

    Summary Background Significant controversy exists in the literature regarding the role of pregnancy in the prognosis of breast cancer. We designed a matched case-case study, matching pregnancy-associated breast cancer (PABC) cases with breast cancer cases for stage, age, and year of diagnosis. Patients and Methods 39 consecutive cases of PABC were matched with 39 premenopausal cases of breast cancer. Univariate and multivariate survival analyses followed by adjustment for stage, grade, estrogen receptor status, and age at diagnosis, were performed. Results Regarding overall survival (OS), univariate analysis pointed to longer OS in non-PABC cases vs. PABC cases. Accordingly, a more advanced stage predicted shorter survival. In the multivariate analysis, the independent aggravating effect mediated by pregnancy persisted. Interestingly, a post hoc nested analysis within PABC cases indicated that the 3rd trimester pointed to shorter OS. The aforementioned results on OS were also replicated during the examination of relapse-free survival. Conclusion Implementing a matched case-case design, the present study points to pregnancy as a poor prognostic factor for breast cancer. PMID:24415971

  4. TOP-10 DATA MINING CASE STUDIES

    OpenAIRE

    GABOR MELLI; XINDONG WU; PAUL BEINAT; FRANCESCO BONCHI; LONGBING CAO; RONG DUAN; CHRISTOS FALOUTSOS; RAYID GHANI; BRENDAN KITTS; BART GOETHALS; GEOFF MCLACHLAN; JIAN PEI; ASHOK SRIVASTAVA; OSMAR ZAÏANE

    2012-01-01

    We report on the panel discussion held at the ICDM'10 conference on the top 10 data mining case studies in order to provide a snapshot of where and how data mining techniques have made significant real-world impact. The tasks covered by 10 case studies range from the detection of anomalies such as cancer, fraud, and system failures to the optimization of organizational operations, and include the automated extraction of information from unstructured sources. From the 10 cases we find that sup...

  5. The advantages of complementing MT profiles in 3-D environments with geomagnetic transfer function and inter-station horizontal magnetic transfer function data: Results from a synthetic case study

    Science.gov (United States)

    Campanyà, Joan; Ogaya, Xènia; Jones, Alan G.; Rath, Volker; Vozar, Jan; Meqbel, Naser

    2016-09-01

    boundaries of the anomalies with low electrical resistivity; and (4) superior imaging of the horizontal continuity of structures with low electrical resistivity. These advantages offer new opportunities for the MT method by making the results from an MT profile in a 3-D environment more convincing, supporting the possibility of high-resolution studies in 3-D areas without expending a large amount of economical and computational resources, and also offering better resolution of targets with high electrical resistivity.

  6. Case studies of attacks on communication networks

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sin Bok; Han, Eon Suk [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-06-15

    Recently, as the computer hardware and communications are developed, the data exchange through inter-networking has been highlighted and the data is being recognized as a great asset. Most of the organizations, businesses and enterprises are open to the external world-computer communication networks, attention must be focused on the securities of the information infrastructure. A government organization has been developing 'Circuits Analyzers', and 'Hacker-Tracking Program' and is struggling to track down sneakers. In this report, we analyze the contents of the cases where the communication network has been invaded, from the past up until now in Korea. This report also contains the result of a study on E-mail security, for the protection of KAERI Integrated Management Information System under which utilizes the CALS concepts and web services. (Author)

  7. A case study in pathway knowledgebase verification

    Directory of Open Access Journals (Sweden)

    Shah Nigam H

    2006-04-01

    Full Text Available Abstract Background Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we would like our tools to take advantage of the information stored in these repositories. But before we can reliably use a pathway knowledgebase as a data source, we need to proofread it to ensure that it can fully support computer-aided information integration and inference. Results We design a series of logical tests to detect potential problems we might encounter using a particular knowledgebase, the Reactome database, with a particular computer-aided hypothesis evaluation tool, HyBrow. We develop an explicit formal language from the language implicit in the Reactome data format and specify a logic to evaluate models expressed using this language. We use the formalism of finite model theory in this work. We then use this logic to formulate tests for desirable properties (such as completeness, consistency, and well-formedness for pathways stored in Reactome. We apply these tests to the publicly available Reactome releases (releases 10 through 14 and compare the results, which highlight Reactome's steady improvement in terms of decreasing inconsistencies. We also investigate and discuss Reactome's potential for supporting computer-aided inference tools. Conclusion The case study described in this work demonstrates that it is possible to use our model theory based approach to identify problems one might encounter using a knowledgebase to support hypothesis evaluation tools. The methodology we use is general and is in no way restricted to the specific knowledgebase employed in this case study. Future application of this methodology will enable us to compare pathway resources with respect to the generic properties such resources will need to possess if they are to support automated reasoning.

  8. Cartography and Population Geography as Current Events: A Case Study

    Science.gov (United States)

    Comenetz, Joshua

    2003-01-01

    The Sanders housing lawsuit in Pennsylvania provides a case study of how to incorporate current events into the teaching of cartography or population geography at the high school or college level. Settlement of the Sanders case resulted in the release of information about the segregation of public housing by race in the Pittsburgh area. The issues…

  9. STUDY OF SIGNIFICANCE OF PLATELET COUNT IN FEVER CASES

    Directory of Open Access Journals (Sweden)

    Vasavilatha

    2015-01-01

    Full Text Available AIM: To study the significance of platelet count in various fevers and also identify the common causes of fever with thrombocytopenia . MATERIALS AND METHODS: 69 patients who were admitted with fever over 2 months of period from 15th October to15th December 2014 in King George Hospital AMC Visakhapatnam studied retrospectively. RESULTS: INCIDENCE: More than half of the cases (52.2% admitted with fever have thrombocytopenia. SEX: The study reveals that irrespective of sex and size of the sample the presentation of fever with/ without thromb ocytopenia could not found any significant difference . Degree of thrombocytopenia in various etiologies: in the present study it is found that out of 15 cases of falciparum malaria 10 cases had thrombocytopenia. Out of 12 undiagnosed cases 8 cases had thro mbocytopenia. Out of 4 cases of gastro intestinal system 3 cases had thrombocytopenia. In the present study it is significantly found that the highest difference is noticed in the presentation of dengue cases. Out of total sample (69 cases it is found tha t 5cases (7.2% of thrombocytopenia with dengue fever were found against 1case (1.4% of dengue fever with normal plate let count. The present study reveals that there is significant difference among various diseases such as malaria 14 (16.6%, dengue feve r 5 (13.9%, Urinary tract infection 2 (5.6%, undiagnosed cases 8 (22.2%. However severe thrombocytopenia (platelets less than 50,000 is seen in14 cases (38.8%out of 36 cases of fever with thrombocytopenia. Further this study reveals that in the cases of malaria 50% of cases reported as severe thrombocytopenia 7cases (19.4% followed by dengue fever3 cases (8.3%. CONCLUSION: Not only malaria, dengue fever and urinary tract infection can also cause severe thrombocytopenia. Fever cases especially with th rombocytopenia show seasonal variations, they are seen commonly in early winter. Febrile thrombocytopenia still presents as atypical and occult forms making

  10. Interventional radiologic placement of tunneled central venous catheters : results and complications in 557 cases

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chan Kyo; Do, Young Soo; Paik, Chul H. [Samsung Medical Center, Sungkyunkwan Univ. School of Medicine, Seoul (Korea, Republic of)] (and others)

    1999-05-01

    To evaluate prospectively the results of interventional radiologic placement of tunneled central venous catheters, and subsequent complications. Between April 1997 and April 1998, a total of 557 tunneled central venous catheters were percutaneously placed in 517 consecutive patients in an interventional radiology suite. The indications were chemotherapy in 533 cases, total parenteral nutrition in 23 and transfusion in one. Complications were evaluated prospectively by means of a chart review, chest radiography, central vein angiography and blood/catheter culture. The technical success rate for tunneled central venous catheter placement was 100% (557/557 cases). The duration of catheter placement ranged from 4 to 356 (mean, 112{+-}4.6) days; Hickman catheters were removed in 252 cases during follow-up. Early complications included 3 cases of pneumothorax(0.5%), 4 cases of local bleeding/hematoma(0.7%), 2 cases of primary malposition(0.4%), and 1 case of catheter leakage(0.2%). Late complications included 42 cases of catheter-related infection(7.5%), 40 cases of venous thrombosis (7.2%), 18 cases of migration (3.2%), 5 cases of catheter / pericatheter of occlusion(0.8%), and 1 case of pseudoaneurysm(0.2%). The infection rate and thrombosis rate per 1000 days were 1.57 and 1.50, respectively. The technical success rate of interventional radiologic placement of tunneled central venous catheters was high. In comparison to conventional surgical placement, it is a more reliable method and leads to fewer complications.

  11. BOOK REVIEW: Case Studies in Knowledge Management

    Directory of Open Access Journals (Sweden)

    Reviewed by Dr. Adnan BOYACI

    2005-10-01

    .The book presents case studies explaining actual applications of KM in a different oforganizational and global settings. Different subjects and issues associated withconstruction of KM system in different kinds of organizations are explored within eachsection. Organizational learning (OL, knowledge, culture and productivity are some ofthe issues tackled with construction of KM system in a variety of organizational andglobal settings.The book is organized into seven sections; KM in support of organizational learning,knowledge management in support of retaining organizational knowledge, knowledgemanagement strategy, issues in knowledge management, KM is support of knowledgetransfer, KM in support of projects, KM outcomes. Each section is related with an area KMresearch.In section I, there are two cases discussing KM in support of OL. The first case is fromLynne P. Cooper, Rebecca L. Nash, Tu-Anh T. Phan, and Teresa R. Bailey and describesdevelopment and operation of knowledge system in order to support learning oforganizational knowledge at the Jet Propulsion Laboratory in USA. It presents in detailimplementation and rollout of the system and argues the results from performance andusage data collected over 19 weeks. The second case is from Brigette McGregor-MacDonald and describes the work of global organizations in its KM efforts to sustain andtransfer learning from global leadership curriculum. It mainly focuses on KM solution162developed to support employees to sustain their learning, to enable them to share theirinsights and experiences with others, and thus increase organizational capability.Section 2 explores using KM to support the retention of organizational knowledge inorganizations where the work forces are in transition. In third chapter in this section HaniAbdel-Aziz, and Khaled Wahba discuss the building of organizational memory informationsystem (OMIS in an Egyptian Professional Services company suffering from knowledgeloss due to high rate of employee turnover

  12. Commentary of the Strahlenschutzkommission on the publication by Martin J. Gardner et al., 'Results of case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria', Brit. Med. Journal 300 (1990) 423-429, and the supplementary publication by Martin J. Gardner et al., 'Methods and basic data of case-control study of leukaemia and lymphoma among young people near Sellafield nuclear plant in West Cumbria', Brit. Med. Journal 300 (1990) 429-434

    International Nuclear Information System (INIS)

    The Strahlenschutzkommission (SSR) states that, upon careful analysis of the publications by Gardner et al., the SSK accepts and supports the conclusions drawn, namely that although the study reveals only four cases indicating a correlation with a radiation exposure of the fathers, further investigations need to be carried out in order to examine the value of the hypothesis of enhanced leukaemia incidence in children of exposed fathers. The SSK states that the results of ongoing studies, to be published by Gardner, will be taken very seriously, but also joins critics who request submission of data on the internal radiation exposure of the fathers. With such data still missing, the SSK does not want to enter into a discussion of dose-response relationships now, as the available data on the external radiation exposure of fathers offers too small a database for discussion of the problems involved. (orig./HP)

  13. Case Study Report about Gender Impact Assessment

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Agustin, Lise Rolandsen

    2013-01-01

    The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish...... Ministry of Employment and the Danish Ministry of Transport, respectively) the aim is to assess the transformative potential of GIA as it is performed in Denmark....

  14. Gigantic Suprapubic Lymphedema: A Case Study.

    Science.gov (United States)

    Tanhaeivash, Roozbeh; Franiel, Tobias; Grimm, Marc-Oliver; Horstmann, Marcus

    2016-08-01

    We present the first case study of idiopathic gigantic suprapubic lymphedema and buried penis treated with puboscrotal reconstruction in a patient with initial extreme obesity after an extensive weight reduction (120 kg). Massive localized lymphedema of the suprapubic region should be differentiated from the scrotal type. Severe lymphedema could not resolve on its own and weight reduction does not seem to be helpful in such cases. PMID:27574599

  15. Case Study Research Methodology in Nursing Research.

    Science.gov (United States)

    Cope, Diane G

    2015-11-01

    Through data collection methods using a holistic approach that focuses on variables in a natural setting, qualitative research methods seek to understand participants' perceptions and interpretations. Common qualitative research methods include ethnography, phenomenology, grounded theory, and historic research. Another type of methodology that has a similar qualitative approach is case study research, which seeks to understand a phenomenon or case from multiple perspectives within a given real-world context.

  16. Gigantic Suprapubic Lymphedema: A Case Study

    Science.gov (United States)

    Tanhaeivash, Roozbeh; Franiel, Tobias; Grimm, Marc-Oliver

    2016-01-01

    We present the first case study of idiopathic gigantic suprapubic lymphedema and buried penis treated with puboscrotal reconstruction in a patient with initial extreme obesity after an extensive weight reduction (120 kg). Massive localized lymphedema of the suprapubic region should be differentiated from the scrotal type. Severe lymphedema could not resolve on its own and weight reduction does not seem to be helpful in such cases. PMID:27574599

  17. Economics, Wildlife Tourism and Conservation: Three Case Studies

    OpenAIRE

    Clement A. Tisdell; Wilson, Clevo

    2004-01-01

    SUMMARY This report presents the results of an economics component of the National Interdisciplinary Project (NIP) on wildlife tourism in Australia. Objectives of Study The main objectives of the study were: • to outline and assess the role that economics can play in the valuation and management of wildlife-based tourism; • to undertake appropriate case studies to highlight the value of economics and its limits in assessing wildlife tourism in each case; • given the importance of nature conse...

  18. Clean Cities Case Study: Barwood Cab Fleet Study Summary

    International Nuclear Information System (INIS)

    Barwood Cab Fleet Study Summary is the second in a new series called''Alternative Fuel Information Case Studies,'' designed to present real-world experiences with alternative fuels to fleet managers and other industry stakeholders

  19. Social Studies Project Evaluation: Case Study and Recommendations.

    Science.gov (United States)

    Napier, John

    1982-01-01

    Describes the development and application of a model for social studies program evaluations. A case study showing how the model's three-step process was used to evaluate the Improving Citizenship Education Project in Fulton County, Georgia is included. (AM)

  20. Connecting Reading and Writing: A Case Study

    Science.gov (United States)

    Li, Zhanfang

    2015-01-01

    Connecting reading and writing, proposed by many scholars, is realized in this case study. The 30 participants in this study are the English majors of the third year in one School of Foreign Languages in Beijing. They are encouraged to write journals every week, based on the source text materials in their Intensive Reading class, with the final…

  1. Collaborative Assessment: Middle School Case Study

    Science.gov (United States)

    Parkison, Paul T.

    2014-01-01

    Utilizing a participant observer research model, a case study of the efficacy of a collaborative assessment methodology within a middle school social studies class was conducted. A review of existing research revealed that students' perceptions of assessment, evaluation, and accountability influence their intrinsic motivation to learn. A…

  2. Measuring marketing performance - A case study

    OpenAIRE

    Laakso, Vesa-Pekka

    2011-01-01

    PURPOSE OF THE STUDY The purpose of this study is to develop a marketing dashboard for a Finnish company that operates in the financial industry. The identification of suitable metrics for assessing marketing performance is considered central. This study proposes a new construct (a dashboard) that aims to providing management relevant information on marketing performance from decision-making perspective. METHODOLOGY AND DATA The methodology is a constructive case study. In the...

  3. Economic utility resulting from CERN contracts (second study)

    International Nuclear Information System (INIS)

    The study attempts to quantify the economic benefit to high technology manufacturing industries involved in CERN contracts, in relation to their sales to CERN. It covers the period 1973-87 and complements an earlier study made in 1973-75 (see CERN Report 75-5). Interviews were carried out in 160 European firms, who supplied estimates of increased sales and cost savings due to CERN contracts. This ''economic utility'' totals 3107 million Swiss francs (up to the year 1987), compared to sales to CERN amounting to 748 million Swiss francs in 1982 prices. It is estimated that, by 1987, CERN's high technology purchases made in 1973-82 will have generated Economic Utility amounting to about 60% of the overall cost of the Organization during the same period. In 1982, about 75% of the increased turnover due to CERN resulted from sales to markets outside high energy particle physics, for example, railways, shipbuilding, refrigeration, power generation and distribution, and health care. The quantification model used is discussed in detail and some specific cases are presented as examples. The industrial managers interviewed during both studies have confirmed that the forecasts made ten years ago were, on average, accurate. (orig.)

  4. Economic utility resulting from CERN contracts (second study)

    International Nuclear Information System (INIS)

    The study attempts to quantify the economic benefit to high technology manufacturing industries involved in CERN contracts, in relation to their sales to CERN. It covers the period 1973-87 and complements an earlier study made in 1973-75 (see CERN Report 75-5). Interviews were carried out in 160 European firms, who supplied estimates of increased sales and cost savings due to CERN contracts. This economic utility totals 3107 million Swiss francs (up to the year 1987), compared to sales to CERN amounting to 748 million Swiss francs in 1982 prices. It is estimated that, by 1987, CERN's high technology purchases made in 1973-82 will have generated Economic high technology purchases made in 1973-82 will have generated Economic Utility amounting to about 60% of the overall cost of the Organization during the same period. In 1982, about 75% of the increased turnover due to CERN resulted from sales to markets outside high energy particle physics, for example, railways, shipbuilding, refrigeration, power generation and distribution, and health care. The quantification model used is discussed in detail and some specific cases are presented as examples. The industrial managers interviewed during both studies have confirmed that the forecasts made ten years ago were, on average, accurate. (orig.)

  5. Economic utility resulting from CERN contracts (second study)

    International Nuclear Information System (INIS)

    The study attempts to quantify the economic benefit to high technology manufacturing industries involved in CERN contracts, in relation to their sales to CERN. It covers the period 1973-87 and complements an earlier study made in 1973-75 (see CERN Report 75-5). Interviews were carried out in 160 European firms, who supplied estimates of increased sales and cost savings due to CERN contracts. This 'economy utility' totals 3107 million Swiss francs (up to the year 1987), compared to sales to CERN amounting to 748 million Swiss francs in 1982 prices. It is estimated that, by 1987, CERN's high technology purchases made in 1973-82 will have generated Economic Utility amounting to about 60% of the overall cost of the Organization during the same period. In 1982, about 75% of the increased turnover due to CERN resulted from sales to markets outside high energy particle physics, for example, railways, shipbuilding, refrigeration, power generation and distribution, and health care. The quantification model used is discussed in detail and some specific cases are presented as examples. The industrial managers interviewed during both studies have confirmed that the forecasts made ten years ago were, on average, accurate. (orig.)

  6. Mining Product Data Models: A Case Study

    Directory of Open Access Journals (Sweden)

    Cristina-Claudia DOLEAN

    2014-01-01

    Full Text Available This paper presents two case studies used to prove the validity of some data-flow mining algorithms. We proposed the data-flow mining algorithms because most part of mining algorithms focuses on the control-flow perspective. First case study uses event logs generated by an ERP system (Navision after we set several trackers on the data elements needed in the process analyzed; while the second case study uses the event logs generated by YAWL system. We offered a general solution of data-flow model extraction from different data sources. In order to apply the data-flow mining algorithms the event logs must comply a certain format (using InputOutput extension. But to respect this format, a set of conversion tools is needed. We depicted the conversion tools used and how we got the data-flow models. Moreover, the data-flow model is compared to the control-flow model.

  7. Integrating Ethics into Case Study Assignments

    Directory of Open Access Journals (Sweden)

    Pamela A. Marshall

    2014-08-01

    Full Text Available I teach an upper-level writing course, Genes, Race, Gender, and Society, designed for Life Science majors, in which I utilize a case study to expose students to ethical ways of thinking.  Students first work through the topical case study and then are challenged to rethink their responses through the lenses of ethics, taking into account different ethical frameworks.  Students then develop their own case study, integrating ethical components.  I want to expose my students to this way of thinking because I see technology being driven by the Jurassic Park phenomenon, "Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should." and want future physicians grounded in a sense of how their actions relate to the greater good.

  8. Shuttle Case Study Collection Website Development

    Science.gov (United States)

    Ransom, Khadijah S.; Johnson, Grace K.

    2012-01-01

    As a continuation from summer 2012, the Shuttle Case Study Collection has been developed using lessons learned documented by NASA engineers, analysts, and contractors. Decades of information related to processing and launching the Space Shuttle is gathered into a single database to provide educators with an alternative means to teach real-world engineering processes. The goal is to provide additional engineering materials that enhance critical thinking, decision making, and problem solving skills. During this second phase of the project, the Shuttle Case Study Collection website was developed. Extensive HTML coding to link downloadable documents, videos, and images was required, as was training to learn NASA's Content Management System (CMS) for website design. As the final stage of the collection development, the website is designed to allow for distribution of information to the public as well as for case study report submissions from other educators online.

  9. Study on heat collector of the solar system utilizing outdoor air. Experimental results in cases of cold and warm regions; Gaiki donyushiki solar system no shunetsubu ni kansuru kenkyu. Kanreichi to ondanchi ni okeru shunetsu jikken to kosatsu

    Energy Technology Data Exchange (ETDEWEB)

    Komano, S.; Ebara, Y. [OM Solar Association, Shizuoka (Japan); Wada, H. [Wada Building Constructors Co. Ltd., Hokkaido (Japan)

    1996-10-27

    An experiment on heat collection was made in the heat collector of a solar system utilizing outdoor air in cold and warm regions. In this system, outdoor air is heated by the air circulation layer on the roof exposed to solar radiation. The heated air is supplied to the object space for heating and ventilation. In the experiment in a cold region, the heat collection characteristics can be adjusted by putting a baffle plate in the air duct according to the experiment of a glass heat collector. The heat collecting air layer on only the iron roof may leak or freeze in the region subject to coldness or heavy snowfall. Therefore, preheat forms the space of a garret, and the preheat temperature comparatively becomes low. The data in which the heat collection characteristics can be adjusted using only a glass heat collector is required corresponding to the regional situation. In the experiment in a warm region, an experiment was made inclusive of the preheat for which outdoor air is absorbed at the eaves. As a result, the heat collection characteristics of preheat were improved. Moreover, a heat collection temperature of about 60{degree}C was obtained on the heat collection surface including the preheat. 1 ref., 12 figs., 3 tabs.

  10. On the pros and cons of the IRMS technique of data processing: uncertainty in results, a case study for determining carbon and oxygen isotopic abundance ratios as CO_2^+

    CERN Document Server

    Datta, B P

    2011-01-01

    The properties of different relationships, representing the basic evaluation as well as its inputs and outputs shaping processes in the CO_2^+ isotope ratio mass spectrometry (IRMS), are studied. It is thus shown that the input generation by using only one auxiliary reference CO2 gas (ARCG) is an accuracy enhancing process, and clarified how the input-by-measurement uncertainty-ratio(s) could be ensured to be tens of folds less than unity. However, the known relationship for using two ARCGs appears to be neither of a logistical base nor better by application. A mathematically correct means for involving two or more than two ARCGs is worked out. However, the same is observed to be worse by behavior, i.e. causes the scale converted data to be more inaccurate than the measured data. The basic evaluation requires solving a set of equations. Using a typical set, it is exemplified that, and explained why, the solutions (determined elemental isotopic abundance ratios (EIARs)) are generally as representative as the i...

  11. SYNONYMS IN ACTION: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Rebecca Clift

    2003-05-01

    Full Text Available This paper discusses what the methods of conversation analysis (CA might have to offer the study of linguistic synonymy. It takes as a case study two items commonly held to be synonyms -'actually' and 'in fact'- and shows considerable differences between the two in their interactional implementation: they are implicated in the prosecution of differing courses of action. Such cases argue that it is analytically more profitable to consider what a lexical item does in the context of talk than what it means.

  12. Repurposing legacy data innovative case studies

    CERN Document Server

    Berman, Jules J

    2015-01-01

    Repurposing Legacy Data: Innovative Case Studies takes a look at how data scientists have re-purposed legacy data, whether their own, or legacy data that has been donated to the public domain. Most of the data stored worldwide is legacy data-data created some time in the past, for a particular purpose, and left in obsolete formats. As with keepsakes in an attic, we retain this information thinking it may have value in the future, though we have no current use for it. The case studies in this book, from such diverse fields as cosmology, quantum physics, high-energy physics, microbiology,

  13. Corporate Social Responsibility : A Case Study

    OpenAIRE

    Björkqvist, Kira

    2012-01-01

    The importance of taking responsibility for the common environmental and social welfare has become of essence in the business world of the 21st century. This thesis provides the reader with knowledge on corporate social responsibility (CSR) and shows the reader a comparative study on how CSR is reported on in three case study companies chosen for this thesis. This thesis is a descriptive study that uses the research method of content analysis to determine the commonalities and differences...

  14. Anorexia in the Adolescence - case study

    Directory of Open Access Journals (Sweden)

    Almeida de Paiva, Maria O

    2010-07-01

    Full Text Available Eating disorders lead to special biological and psychological states. The result of the total lack of food is treated in a distinct way by anorexia. Nutritionists have thus had difficulty in coming to an agreement on the best therapy to prevent such disorders. First it is essential to understand which treatment aims are and then to attempt to know how the several treatment models used nowadays can reach those aims. Someone who suffers from eating disorders, together with an inner deformation, suffers from too much sensitiveness. In order to solve these problems, one needs a change in the relationship with oneself, with the others and with the world. This study presents a teenager’s case study – Anorexia. Is, in fact, a problem that society faces and can’t ignore. Many youngsters have already died and others are following their steps. But there are also those ones that succeeded in overcoming the problem and now are reporting their stories.

  15. Odontoma: a retrospective study of 73 cases

    Energy Technology Data Exchange (ETDEWEB)

    An, Seo Young; An, Chang Hyeon; Choi, Karp Shik [School of Dentistry, Kyungpook National University, Daegu (Korea, Republic of)

    2012-06-15

    The purpose of the present study was to retrospectively evaluate the clinical findings and treatment results for impacted permanent teeth associated with odontomas. We retrospectively investigated 73 odontomas in 72 patients who visited Kyungpook National University Dental Hospital from April 2004 through November 2011. The study was performed using medical records, panoramic radiographs, and pathological reports. Data gathered included age, gender, location, chief complaints, effects on dentition, and treatment of odontoma and the impacted tooth associated with odontoma. Most compound odontomas (46.7%) were found in the second decade and complex odontomas were not related to age. Odontomas showed no gender predilection. Fifty-five cases (75.3%) of odontomas were detected on routine dental radiographs. Sixty percent of compound odontomas occurred in the canine area and 57.1% of complex odontomas in the molar areas. Impaction of permanent teeth (61.6%) was the most common complication on the adjacent teeth. Most odontomas (84.9%) were removed surgically and impacted permanent teeth were managed by surgical removal (53.2%), orthodontic treatment (25.5%), or surgical repositioning (6.4%). There was a statistically significant relation between age and preservation of the impacted permanent teeth associated with odontomas (p<0.01). Early detection and treatment of odontomas increase the possibility of preservation of the impacted tooth. Therefore, it would be suggested that periodic panoramic examination during the first and second decade of life might be beneficial for the early detection and better prognosis of odontomas.

  16. Antineutrino reactor safeguards - a case study

    CERN Document Server

    Christensen, Eric; Jaffke, Patrick

    2013-01-01

    Antineutrinos have been proposed as a means of reactor safeguards for more than 30 years and there has been impressive experimental progress in neutrino detection. In this paper we conduct, for the first time, a case study of the application of antineutrino safeguards to a real-world scenario - the North Korean nuclear crisis in 1994. We derive detection limits to a partial or full core discharge in 1989 based on actual IAEA safeguards access and find that two independent methods would have yielded positive evidence for a second core with very high confidence. To generalize our results, we provide detailed estimates for the sensitivity to the plutonium content of various types of reactors, including most types of plutonium production reactors, based on detailed reactor simulations. A key finding of this study is that a wide class of reactors with a thermal power of less than 0.1-1 GWth can be safeguarded achieving IAEA goals for quantitative sensitivity and timeliness with detectors right outside the reactor ...

  17. Unexplained False Negative Results in Noninvasive Prenatal Testing : Two Cases Involving Trisomies 13 and 18

    NARCIS (Netherlands)

    Hochstenbach, R; Page-Christiaens, G C M L; van Oppen, A C C; Lichtenbelt, K D; van Harssel, J J T; Brouwer, T; Manten, G T R; van Zon, P; Elferink, M; Kusters, K; Akkermans, O; Ploos van Amstel, J K; Schuring-Blom, G H

    2015-01-01

    Noninvasive prenatal testing (NIPT) validation studies show high sensitivity and specificity for detection of trisomies 13, 18, and 21. False negative cases have rarely been reported. We describe a false negative case of trisomy 13 and another of trisomy 18 in which NIPT was commercially marketed di

  18. A boy with 9p+ resulting from maternal t(4;9) translocation: a case report

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Increasing cases of 9p syndrome have been reported since the first description in 1970.In the present case, a extra segment of the end of chromosome 9p resulting from a maternally inherited translocation t(4;9)(q31;p24) was described in a liveborn boy with mental retardation and multiple congenital anomalies. The extra part of chromosome 9p includes segment of the chromosome region 4q31→qter of his mother but deletes a small segment 9p24→pter. To our knowledge, this is the first case described in a liveborn child. This paper also includes a review and tabulation of clinical features seen in the 34 reported cases. The new case had most characteristics reported cases besides worried-face, fat and abnormal lower digestion tract, which is a modification and double expansion of the previous summarization on 9p syndrome.

  19. False Negative NIPT Results: Risk Figures for Chromosomes 13, 18 and 21 Based on Chorionic Villi Results in 5967 Cases and Literature Review.

    Directory of Open Access Journals (Sweden)

    Diane Van Opstal

    Full Text Available Non-invasive prenatal testing (NIPT demonstrated a small chance for a false negative result. Since the "fetal" DNA in maternal blood originates from the cytotrophoblast of chorionic villi (CV, some false negative results will have a biological origin. Based on our experience with cytogenetic studies of CV, we tried to estimate this risk. 5967 CV samples of pregnancies at high risk for common aneuplodies were cytogenetically investigated in our centre between January 2000 and December 2011. All cases of fetal trisomy 13, 18 and 21 were retrospectively studied for the presence of a normal karyotype or mosaicism < 30% in short-term cultured (STC- villi. 404 cases of trisomies 13, 18 and 21 were found amongst 5967 samples (6,8%. Of these 404 cases, 14 (3,7% had a normal or low mosaic karyotype in STC-villi and therefore would potentially be missed with NIPT. It involved 2% (5/242 of all trisomy 21 cases and 7.3% (9/123 of all trisomy 18 cases. In 1:426 (14/5967 NIPT samples of patients at high risk for common aneuploidies, a trisomy 18 or 21 will potentially be missed due to the biological phenomenon of absence of the chromosome aberration in the cytotrophoblast.

  20. Industrial process heat case studies. [PROSYS/ECONMAT code

    Energy Technology Data Exchange (ETDEWEB)

    Hooker, D.W.; May, E.K.; West, R.E.

    1980-05-01

    Commercially available solar collectors have the potential to provide a large fraction of the energy consumed for industrial process heat (IPH). Detailed case studies of individual industrial plants are required in order to make an accurate assessment of the technical and economic feasibility of applications. This report documents the results of seven such case studies. The objectives of the case study program are to determine the near-term feasibility of solar IPH in selected industries, identify energy conservation measures, identify conditions of IPH systems that affect solar applications, test SERI's IPH analysis software (PROSYS/ECONOMAT), disseminate information to the industrial community, and provide inputs to the SERI research program. The detailed results from the case studies are presented. Although few near-term, economical solar applications were found, the conditions that would enhance the opportunities for solar IPH applications are identified.

  1. Rocket injector anomalies study. Volume 2: Results of parametric studies

    Science.gov (United States)

    Przekwas, A. J.; Singhal, A. K.; Tam, L. T.

    1984-01-01

    The employment of a existing computer program to simulate three dimensional two phase gas spray flows in liquid propellant rocket engines. This was accomplished by modification of an existing three dimensional computer program (REFLAN3D) with Euler/Lagrange approach for simulating two phase spray flow, evaporation and combustion. The modified code is referred to as REFLAN3D-SPRAY. Computational studies of the model rocket engine combustion chamber are presented. The parametric studies of the two phase flow and combustion shows qualitatively correct response for variations in geometrical and physical parameters. The injection nonuniformity test with blocked central fuel injector holes shows significant changes in the central flame core and minor influence on the wall heat transfer fluxes.

  2. RESULTS FROM BI-CONTACT® TOTAL ELBOW ARTHROPLASTY: MULTICENTER STUDY

    Science.gov (United States)

    Benegas, Eduardo; Malavolta, Eduardo Angeli; Gracitelli, Mauro Emilio Conforto; de Sousa, Augusto Tadeu Barros; Miyazaki, Alberto Naoki; Fregoneze, Marcelo; Ikemoto, Roberto Yukio; Murachovsky, Joel; Matsumoto, Marcelo Hide; Tamaoki, Marcel Jun Sugawara; Neto, Arnaldo Amado Ferreira

    2015-01-01

    Objective: To describe the initial experience of four orthopedic clinics from using Bi-Contact® total elbow arthroplasty (TEA), reporting the results and complications of the procedure. Methods: This was a retrospective study, through analysis on the medical records of patients who underwent primary TEA using a prosthesis model developed in conjunction with IOT-HCFMUSP. Forty-six elbows (45 patients) that were operated at four orthopedic clinics between 2000 and 2009 were evaluated. Results: The majority of the patients were female (74%), and the median age was 62.5 years. The diagnoses encountered were trauma sequelae (47.83%), rheumatoid arthritis (32.61%), primary osteoarthrosis (8.7%), acute fractures (6.52%) and heterotopic ossification (2.17%). The median length of follow-up was 2.08 years (0.25-9). The procedure significantly alleviated pain and improved range of motion. It was observed that at least one complication was present in 69.57% of the cases, and the main ones were infection (28.26%), need for revision (28.26%), intraoperative fracture (15.22%) and aseptic loosening (15.22%). Conclusion: Bi-Contact® TEA provided significant alleviation of pain and improvement of range of motion in the present series. The complication rate was high, and the most frequently observed complications were infection, aseptic loosening and intraoperative fracture. PMID:27027055

  3. Icosahedral Shallow Water Model (ICOSWM: results of shallow water test cases and sensitivity to model parameters

    Directory of Open Access Journals (Sweden)

    T. Heinze

    2009-06-01

    Full Text Available The Icosahedral Shallow Water Model (ICOSWM has been a first step in the development of the ICON (acronym for ICOsahedral Nonhydrostatic models. ICON is a joint project of the Max Planck Institute for Meteorology in Hamburg (MPI-M and Deutscher Wetterdienst (DWD for the development of new unified general circulation models for climate modeling and numerical weather forecasting on global or regional domains. A short description of ICOSWM is given. Standard test cases are used to test the performance of ICOSWM. The National Center for Atmospheric Research (NCAR Spectral Transform Shallow Water Model (STSWM has been used as reference for test cases without an analytical solution. The sensitivity of the model results to different model parameters is studied. The kinetic energy spectra are calculated and compared to the STSWM spectra. A comparison to the shallow water version of the current operational model GME at DWD is presented. In the framework of the ICON project an hydrostatic dynamical core has been developed, and a local grid refinement option and a non-hydrostatic dynamical core are under development. The results presented in this paper use the ICOSWM version at the end of 2008 and are a benchmark for the new options implemented in the development of these models.

  4. Collagenous ileitis: a study of 13 cases.

    Science.gov (United States)

    O'Brien, Blake Hugh; McClymont, Kelly; Brown, Ian

    2011-08-01

    Collagenous ileitis (CI), characterized by subepithelial collagen deposition in the terminal ileum, is an uncommon condition. The few cases reported to date have been associated with collagenous colitis (CC) or lymphocytic colitis. Thirteen cases of CI retrieved over a 9-year period were retrospectively studied. There were 7 female and 6 male patients, with an age range of 39 to 72 years (mean, 64 y). Two groups were identified: (1) CI associated with collagenous or lymphocytic disease elsewhere in the gastrointestinal tract and (2) CI as an isolated process. Diarrhea was the presenting symptom in 11 cases. Most patients had no regular medication use. Subepithelial collagen thickness ranged from 15 to 100 μm (mean, 32 μm) and involved 5% to 80% of the subepithelial region of the submitted biopsies. Six cases had >25 intraepithelial lymphocytes (IELs)/100 epithelial cells, and villous blunting was observed in 11 cases. Chronic inflammation of the lamina propria was present in 9 cases, and focal neutrophil infiltration was identified in 3 cases. In biopsies taken from other sites, 7 of 13 colonic biopsies showed CC, 4 of 9 gastric biopsies showed collagenous gastritis, and 2 of 10 duodenal biopsies were abnormal with collagenous sprue (n=1) and partial villous atrophy and increased IELs (n=1) (both celiac disease related). Resolution of the subepithelial collagen deposition was found in the 1 case in which follow-up of terminal ileal biopsies were taken. There was partial or complete resolution of symptoms in 6 of 9 patients for whom follow-up information was available. PMID:21716082

  5. Laser fusion study. Final report, volume I, study results

    International Nuclear Information System (INIS)

    The primary goal of this study was to devise, evaluate, and conceptually design a complete, end-to-end, alignment system capable of handling 30 to 32 Shiva amplifier chains to specified accuracies in space and time. A secondary goal was to accomplish the primary goal with an acceptably low development and procurement cost and with an acceptably high day-after-day performance reliability. This report presents such a system: it is comprised of sensors, actuating mechanisms, controls, and displays that perform well within the current art-state. (U.S.)

  6. The bussola study. Final results, conclusions and proposals

    Directory of Open Access Journals (Sweden)

    Antonio Luiz da Silva Brasileiro

    2000-09-01

    Full Text Available OBJECTIVE: To evaluate the use of thrombolytic and acetylsalicylic acid therapies in acute myocardial infarct patients as well as the availability of technical and human resources for the care of these patients in the emergency units of the city of Rio de Janeiro. Additional objectives were the evaluation of the use of primary angioplasty and the level of acceptance of SBC /RJ as an entity responsible for programs of continued medical education. METHODS: Interviews with physicians at 46 emergency units in the city of Rio de Janeiro. RESULTS: Of the 46 emergency units inspected, a policy of encouragement to use thrombolytic therapy was only prescribed in 6.5%. In 1/3 of the public wards no thrombolytic agents were available, and in none of them was access to primary angioplasty regularly available; 45.9% did not offer the minimal conditions required for the handling of cases of acute myocardial infarction; 60% of the physicians on-call (at both public and private emergency units, appeared not to know the importance of the use of acetylsalicylic acid in acute myocardial infarct patients; all physicians interviewed would participate in programs of continued medical education organized by the SBC/RJ. CONCLUSION: The study suggests there was: 1 the low probability of the use of thrombolytic therapy in the majority of the emergency units in of the city of Rio de Janeiro due to the inadequate policy of waiting for the transfer of the patient to coronary or intensive care unit; 2 a low awareness to the importance of early use of acetylsalic acid in acute myocardial infarct; 3 half of the emergency units of the public net do not have the minimal conditions required for the handling of cases of acute myocardial infarction; 4 a high level of credibility exists that would enable the SBC/RJ to set up programs for continued medical education to change the mentality regarding the use of thrombolytic therapy and of acetylsalicylic acid.

  7. Evaluation of School Uniform Policy in Turkey: A Case Study

    Science.gov (United States)

    Cinoglu, Mustafa

    2014-01-01

    The purpose of this study is to evaluate the results of current school uniform policies according to views of stakeholders. Descriptive case study method was used for this study to understand the concerns of the stakeholders about school uniforms. Data was collected through interviews with stakeholders and also reviewing the documents in TOKI…

  8. Bullous disorders in Konya: A study of 93 cases

    Directory of Open Access Journals (Sweden)

    Munise Daye

    2013-12-01

    Full Text Available Background and Design: Bullous disorders are a group of disorders caused by specific antibodies against tissue adhesion molecules in skin and mucosa or genetic inheritance. There are limited detailed epidemiological studies about bullous disorders in Turkey. In this study we evaluated the demographic, clinical, immunopathologic, course and follow-up properties, cases in Konya. Most of cases were in pemphigus and bullous pemphigoid group, so we gave more information about them. Materials and Methods: Ninty three cases that are followed up during the period of 2006-2012 were included in our study. Results: Female cases were %53,8, male cases were %46,2. The mean age was 52,9. In all of cases; %37,6 cases were pemhigus vulgaris, % 34,4 bullous pemphigoid, %15 herediter epidermolysis bullosa, %4,3 were dermatitis herpetiformis, %4,3 were pemphigus foliaceus, %2,2 pemphigus vegetans, %1,1 Hailey- Hailey disease, %1,1 cicatricial pemphigoid. Mean age of Pemhigus vulgaris onset was 45,9 year and mostly it was observed in females. Pemhigus vulgaris has been started at oral mucosae and the time for diagnosis of pemhigus vulgaris, which began at oral mucosae, was longer than other geogrophic regions. Mean age bullous pemphigoid onset was 70 year and mostly it was observed in females. In % 12,5 of cases disease started at oral mucosae. None of the cases had additional autoimmune disorder. We have treated 25 cases with systemic corticosteriods, 41 cases with systemic corticosteriods and adjuvan agents, 11 cases with only one of adjuvan agents, 16 cases with only local streoids. Conclusions: We report the demographic, clinical, immunopathologic, course and follow-up properties of the bullous disorders in Konya.

  9. Microbial study of meningitis and encephalitis cases.

    Science.gov (United States)

    Selim, Heba S; El-Barrawy, Mohamed A; Rakha, Magda E; Yingst, Samuel L; Baskharoun, Magda F

    2007-01-01

    Meningitis and/or encephalitis can pose a serious public health problem especially during outbreaks. A rapid and accurate diagnosis is important for effective earlier treatment. This study aimed to identify the possible microbial causes of meningitis and/or encephalitis cases. CSF and serum samples were collected from 322 patients who had signs and symptoms suggestive of meningitis and/or encephalitis. Out of 250 cases with confirmed clinical diagnosis, 83 (33.2%) were definitely diagnosed as bacterial meningitis and/or encephalitis cases (by using CSF culture, biochemical tests, latex agglutination test, and CSF stain), 17 (6.8%) were definitely diagnosed as having viral causes ( by viral isolation on tissue culture, PCR and ELISA), and one (0.4%) was diagnosed as fungal meningitis case (by India ink stain, culture, and biochemical tests). Also, there was one encephalitis case with positive serum ELISA IgM antibodies against Sandfly scilian virus. N. meningitidis, S. pneumonia and M. tuberculosis were the most frequently detected bacterial agents, while Enteroviruses, herpes simplex viruses and varicella zoster viruses were the most common viral agents encountered. Further studies are needed to assess the role of different microbial agents in CNS infections and their effective methods of diagnosis.

  10. Teaching the Holocaust through Case Study

    Science.gov (United States)

    Misco, Thomas

    2009-01-01

    This article responds to the curricular challenges teachers face with Holocaust education, including cursory treatments and a lack of focus on individual experiences. First, the author argues for a case-study approach to help students reengage concrete and complex features of the Holocaust as a point of departure for subsequent inquiry. In…

  11. Lifelong Learning in SMEs: A Case Study.

    Science.gov (United States)

    Holden, Rick; Smith, Vikki; Devins, Dave

    2002-01-01

    Learning centers using information-communications technologies were established in three British industrial estates. A case study of one organization shows the center contributed to lifelong learning and enhanced information technology training and employee confidence. Transfer of training and productivity improvements were not as clear. (Contains…

  12. It's Not Funny: A Case Study

    Science.gov (United States)

    Méndez-Morse, Sylvia

    2015-01-01

    This case study may be used with personnel supervision, school law, and other school leadership courses. It describes the behavior and actions of one teacher toward another. Student discussions can focus on supervision, workplace mobbing, workplace bullying, as well as sexual harassment. Students should focus on a school leader's role in such…

  13. Physical Science Connected Classrooms: Case Studies

    Science.gov (United States)

    Irving, Karen; Sanalan, Vehbi; Shirley, Melissa

    2009-01-01

    Case-study descriptions of secondary and middle school classrooms in diverse contexts provide examples of how teachers implement connected classroom technology to facilitate formative assessment in science instruction. Connected classroom technology refers to a networked system of handheld devices designed for classroom use. Teachers were…

  14. The Verbal Noncommunicator: A Case Study.

    Science.gov (United States)

    Fujiki, Martin; Brinton, Bonnie

    1991-01-01

    This article presents a case study of a nine-year-old male with language impairment and specific pragmatic disabilities. His interactions with an adult, a language age-matched peer, and a chronological age-matched peer were observed and analyzed to determine conversational responsiveness and assertiveness. Findings support Fey's (1986) verbal…

  15. Performance-Related Pay: A Case Study.

    Science.gov (United States)

    Swabe, A. I. R.

    1989-01-01

    Discusses performance-related pay and why the system was introduced, how it was negotiated, and how it has operated. The case study illustrated is in a British financial services company where the system was negotiated in 1986 and began in 1987. (JOW)

  16. Acquaintance Rape: A Case Study Approach.

    Science.gov (United States)

    Marinelli, Rosalie D.

    1994-01-01

    Describes a case study approach to acquaintance rape used in a Personal Health and Lifestyles course at the University of Nevada in Reno that allows students to discuss the characters in a scenario, an instructional process seen as less threatening than describing personal experiences. (MDM)

  17. A Case Study on Distributed Antenna Systems

    DEFF Research Database (Denmark)

    Sørensen, Troels Bundgaard

    2007-01-01

    to changing interference and traffic conditions are less common, despite their potential for increased capacity in comparison with traditional (pico)cellular based concepts. This chapter explores a case study of one indoor environment where the site-specific propagation characteristics are taken into account...

  18. Case Studies on Globalization and Money Laundering

    OpenAIRE

    Eckhard Freyer

    2008-01-01

    Financial globalization has greatly improved the efficiency of capital transfers around the world, with the cost of facilitating criminal money laundering activities. Based on case studies on conditions for money laundering in the process of globalization and transformation in Europe, are discussed the challenges that a “global financial village” must confront.

  19. A CASE STUDY OF ENVIRONMENTAL DATA MANAGEMENT

    Science.gov (United States)

    In order to support our ongoing research in watershed ecology and global climate change, we gather and analyze environmental data from several government agencies. This case study demonstrates a researcher’s approach to accessing, organizing, and using intersectoral data. T...

  20. Comparative Environmental Threat Analysis: Three Case Studies.

    Science.gov (United States)

    Latour, J. B.; Reiling, R.

    1994-01-01

    Reviews how carrying capacity for different environmental problems is operationalized. Discusses whether it is possible to compare threats, using the exceeding of carrying capacity as a yardstick. Points out problems in comparative threat analysis using three case studies: threats to European groundwater resources, threats to ecosystems in Europe,…

  1. Firefighter Workplace Learning: An Exploratory Case Study

    Science.gov (United States)

    Tracey, Edward A.

    2014-01-01

    Despite there being a significant amount of research investigating workplace learning, research exploring firefighter workplace learning is almost nonexistent. The purpose of this qualitative multi-case study was to explore how firefighters conceptualize, report, and practice workplace learning. The researcher also investigated how firefighters…

  2. Climate wise case study compendium: Report 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    This case study compendium is one of several Climate Wise tools available to help interested companies identify cost-effective options. Climate Wise, a private-public partnership program, is a key Federal initiative to return greenhouse gas emissions to 1990 levels by 2000.

  3. Fraternization in Accounting Firms: A Case Study

    Science.gov (United States)

    Heinze, Tim; Kizirian, Tim; Leese, Wallace

    2004-01-01

    This case study sheds light on how to avoid risks caused by manager-subordinate dating relationships (fraternization) such as employee misunderstandings, retaliation charges, favoritism complaints, wrongful termination lawsuits, and sexual harassment lawsuits, as well as associated ethical risks. Risk avoidance can be accomplished through a better…

  4. ESL and Digital Video Integration: Case Studies

    Science.gov (United States)

    Li, J., Ed.; Gromik, N., Ed.; Edwards, N., Ed.

    2013-01-01

    It should come as no surprise that digital video technology is of particular interest to English language learners; students are drawn to its visual appeal and vibrant creative potential. The seven original case studies in this book demonstrate how video can be an effective and powerful tool to create fluid, fun, interactive, and collaborative…

  5. Mobile Technologies Adoption: An Exploratory Case Study

    Institute of Scientific and Technical Information of China (English)

    CHU Yan; HUANG Lihua

    2008-01-01

    Based on the theory of task-technology fit and literature review of mobile technology acceptance, a research model is presented based on the features of mobile technologies and the actual usage of mobile applications in business environments, which identifies the characteristics of mobile applications and fitting tasks. An exploratory case is studied to understand how ABC Company, Hong Kong, utilizes mobile selling applications in their sales management process. This study gives some managerial suggestions for enterprises to successfully use mobile applications.

  6. Case studies on selected natural food antioxidants

    OpenAIRE

    Herrero, Miguel; Mendiola, J. A.; Cifuentes, Alejandro; Ibáñez, Elena

    2013-01-01

    In this chapter, a broad description of several case studies related to common antioxidants found in food-related products is presented. In this regard, special attention is put on the novel advanced environmentally-friendly extraction methods nowadays employed to extract and purify those potent antioxidants from natural matrices. A brief description of these extraction processes is provided together with some of the instrumentation needed. Besides, the studies carried out so f...

  7. MARKET INTEGRATION: CASE STUDIES OF STRUCTURAL CHANGE

    OpenAIRE

    Franken, Jason R.V.; Parcell, Joseph L.

    2003-01-01

    The grain/oilseed industry is undergoing considerable structural change in the form of mergers and the addition of new processing facilities to add value beyond commodity grade. The rapid structural changes in this industry call into question the relevance of previous research conducted in these areas. Focusing on two structural change events in northeast Missouri as case studies provides an incisive glimpse at the larger impact of structural change on the grain/oilseed industry. This study a...

  8. Can We Generalize from Case Studies?

    OpenAIRE

    Paul F. Steinberg

    2015-01-01

    This article considers the role of generalization in comparative case studies, using as exemplars the contributions to this special issue on climate change politics. As a research practice, generalization is a logical argument for extending one’s claims beyond the data, positing a connection between events that were studied and those that were not. No methodological tradition is exempt from the requirement to demonstrate a compelling logic of generalization. The article presents a taxonomy of...

  9. CAT: A CASE STUDY OF GRE

    Institute of Scientific and Technical Information of China (English)

    WangZe; ChenJiliang

    2004-01-01

    The Computer Adaptive Testing (CAT) has developedsuccessfully with its adoption by testing agencies. The authors ofthis paper point out the advantages and disadvantages of CATsand then take GRE as a case study to probe into the scoringalgorithm in CAT. By analyzing some typical score reports ofcomputer-adaptive GRE General Test, they study some majorfactors affecting the final score such as the percentage ofcorrectness and difficulty levels.

  10. VINCRISTINE INDUCED NEUROTOXICITY: STUDY OF 75 CASES

    Directory of Open Access Journals (Sweden)

    M.T. Arzanian

    2009-08-01

    Full Text Available ObjectiveConcern for side-effects of therapy related to treatment of childhood malignancies is becoming an increasingly important topic. In this study, we evaluated extent of vincristine (VCR induced neurotoxicity in a group of children who underwent chemotherapy, with VCR being part of the regimen.Materials & MethodsIn this investigation, for 75 children (54% boys, 46% girls, aged between 1 to 14 (mean 6.5±4.3 years, serial weekly neurological examinations were performed; of the 75, 70 had acute lymphoblastic leukemia and 5 Wilm's tumor. All patients were on a chemotherapy protocol of at least 4 consecutive VCR (1.5mg/m2 injections.ResultsDecreased deep tendons reflexes were seen in the Achilles reflex in 78%, and the patellar reflex in 53% of patients. Muscle weakness was found in 70% of patients, being mild in 76% of them. Four  percent of patients showed severe weakness. Petosis, jaw pain, hoarseness, abdominal pain and constipation were seen in 15%, 6%, 12%, 12% and 12% respectively. Paresthesia was observed in 32 of 52 patients, over 4 years old. No cases of foot drop, urinary retention or facial nerve palsy were seen in this patient group.ConclusionChildren on usual doses of vincristine regimen may have neuropathic side effects but most of these side effects are mild and not troublesome.Key words: Vincristine, neuropathy, neurotoxicity, side effect

  11. Otic Barotrauma Resulting from Continuous Positive Airway Pressure: Case Report and Literature Review

    Science.gov (United States)

    McCormick, Justin P.; Hildrew, Douglas M.; Lawlor, Claire M.; Guittard, Jesse A.; Worley, N. Knight

    2016-01-01

    Background: Obstructive sleep apnea (OSA) is a growing problem affecting millions of people in the United States. The prevalence of OSA has risen drastically in the past few decades concurrently with the increasing prevalence of obesity. Subsequently, there has been an ever-increasing rise in the use of continuous positive airway pressure (CPAP) devices. While using CPAP devices may lead to many adverse effects, the majority of these effects are described as relatively benign. Case Report: We describe the detailed clinical course and outcome for a patient with otic barotrauma as a result of excessive self-titration of CPAP therapy in an in-home setting. We also discuss the pathophysiology of otic barotrauma and present a review of current literature on the topic. Conclusion: While the benefits of CPAP are clear, we must take into account the rare but possible effects on ear structure and function. Many studies describe an increase in middle ear pressure with the use of CPAP, but few describe the effects of this increased pressure on the middle ear, such as the otic barotrauma described in this case. Given the increased prevalence of OSA, it is important to understand the risks associated with CPAP therapy. PMID:27303224

  12. Using case studies in management education: the student perspective.

    OpenAIRE

    BRENNAN, ROSS; Ahmad, S. Jaseem

    2005-01-01

    Case studies are widely used in management education. Most of the literature discussing the case study method has reflected the perspective of the teacher, implying a teacher-centred view of the case study as a learning strategy. Little is known about the student perspective on case studies. If we are to use the case study method as a component of a student-centred learning experience, then we must know how students perceive case studies, and understand the differences in attitude...

  13. Where Does Literary Study Happen? Two Case Studies

    Science.gov (United States)

    Billington, Josie; Sperlinger, Tom

    2011-01-01

    This article explores the question of where literary study happens through reflection on two case studies. The article examines projects within two UK English departments, which were designed to allow students of literature to engage with local communities as part of their studies. The implications of this work are considered for curriculum…

  14. Vitiligo: A study of 120 cases

    Directory of Open Access Journals (Sweden)

    Kar P

    2001-11-01

    Full Text Available Vitiligo is a common pignientary disorder and of major social and cosmetic concern in India. Purpose of the study was to find out age at onset and sex incidence in vitiligo, role of hereditary factors and associations with other diseases. 120 self reporting vitiligo patients attending out patient department of a service hospital were selected for the study and this data was analysed. In the present series out of 120 cases 62 (51.6% were males and 58(48.35%were females. There was practically no difference in sex incidence. The lowest age of onset was two years and the oldest was 65 years. In the majority of patients,52(43.2%, disease started before twenty years of age.8 (6.6% cases gave definite family history of vitiligo. Exposed areas of the body were commonly affected in majority (66.6% of cases. The legs were commonest site of involvement in 60(50% cases. Circunicript type of vitiligo (46.6% was heading the list. Majority of patients (56.6% had multiple lesions. Diabetes mellitus was found in 2 (2.6% patients. Cause of vitiligo is still idiopathic. Hereditary factors hardly play any role in manifestation of vitiligo

  15. Transformational change in healthcare: an examination of four case studies.

    Science.gov (United States)

    Charlesworth, Kate; Jamieson, Maggie; Davey, Rachel; Butler, Colin D

    2016-04-01

    Objectives Healthcare leaders around the world are calling for radical, transformational change of our health and care systems. This will be a difficult and complex task. In this article, we examine case studies in which transformational change has been achieved, and seek to learn from these experiences. Methods We used the case study method to investigate examples of transformational change in healthcare. The case studies were identified from preliminary doctoral research into the transition towards future sustainable health and social care systems. Evidence was collected from multiple sources, key features of each case study were displayed in a matrix and thematic analysis was conducted. The results are presented in narrative form. Results Four case studies were selected: two from the US, one from Australia and one from the UK. The notable features are discussed for each case study. There were many common factors: a well communicated vision, innovative redesign, extensive consultation and engagement with staff and patients, performance management, automated information management and high-quality leadership. Conclusions Although there were some notable differences between the case studies, overall the characteristics of success were similar and collectively provide a blueprint for transformational change in healthcare. What is known about the topic? Healthcare leaders around the world are calling for radical redesign of our systems in order to meet the challenges of modern society. What does this paper add? There are some remarkable examples of transformational change in healthcare. The key factors in success are similar across the case studies. What are the implications for practitioners? Collectively, these key factors can guide future attempts at transformational change in healthcare. PMID:26188916

  16. The Pendulum A Case Study in Physics

    CERN Document Server

    Baker, Gregory L

    2005-01-01

    The pendulum: a case study in physics is a unique book in several ways. Firstly, it is a comprehensive quantitative study of one physical system, the pendulum, from the viewpoint of elementary and more advanced classical physics, modern chaotic dynamics, and quantum mechanics. In addition, coupled pendulums and pendulum analogs of superconducting devices are also discussed. Secondly, this book treats the physics of the pendulum within a historical and cultural context,showing, for example, that the pendulum has been intimately connected with studies of the earth's density, the earth's motion,

  17. Mucocele in Lower Lip as a Result of Improper Use of Feeding Bottle: A Case Report

    OpenAIRE

    S Ashok Kumar; Mahesh Ramakrishnan

    2013-01-01

    A rare case of mucocele associated with improper feeding habit has been presented. An eight-month old male child presented with swelling in lower lip which was noticed by his mother a week earlier. A thorough clinical examination and history taking gave a diagnosis of mucocele resulting from improper use of feeding bottle. This case highlights and discusses the history, the clinical along with histologic features, and the clinical management of this lesion. Awareness of such an entity and the...

  18. Fluorine-18 fluorodeoxyglucose positron emission tomography in infectious bone diseases: results of histologically confirmed cases

    International Nuclear Information System (INIS)

    The aim of this study was to evaluate the clinical use of fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) in acute and chronic osteomyelitis and inflammatory spondylitis. The study population comprised 21 patients suspected of having acute or chronic osteomyelitis or inflammatory spondylitis. Fifteen of these patients subsequently underwent surgery. FDG-PET results were correlated with histopathological findings. The remaining six patients, who underwent conservative therapy, were excluded from any further evaluation due to the lack of histopathological data. The histopathological findings revealed osteomyelitis or inflammatory spondylitis in all 15 patients: seven patients had acute osteomyelitis and eight patients had chronic osteomyelitis or inflammatory spondylitis. FDG-PET yielded 15 true-positive results. The tracer uptake correlated with the histopathological findings in each case. Bone scintigraphy performed in 11 patients yielded ten true-positive results and one false-negative result. Follow-up carried out on two patients revealed normal or clearly reduced tracer uptake, which correlated with a normalisation of clinical data. In early postoperative follow-up it was impossible to differentiate between postsurgical reactive changes and further infection using FDG-PET. It is concluded that acute and chronic osteomyelitis of the peripheral as well as the central skeleton can be detected using FDG-PET. Osteomyelitis can be differentiated from soft tissue infection surrounding the bone. Unlike computed tomography and magnetic resonance imaging, FDG-PET is not affected by metal implants used for fixing fractures. FDG-PET demonstrated promising initial results with respect to treatment monitoring. Nevertheless, in the early postoperative phase FDG-PET seems to be of limited value owing to unspecific tracer uptake. (orig.)

  19. Fluorine-18 fluorodeoxyglucose positron emission tomography in infectious bone diseases: results of histologically confirmed cases

    Energy Technology Data Exchange (ETDEWEB)

    Kaelicke, T. [Dept. of Surgery, University of Bochum (Germany); Schmitz, A.; Schmitt, O. [Dept. of Orthopaedics, University of Bonn (Germany); Risse, J.H.; Biersack, H.J. [Dept. of Nuclear Medicine, University of Bonn (Germany); Arens, S.; Hansis, M. [Dept. of Trauma Surgery, University of Bonn (Germany); Keller, E. [Department of Radiology, University of Bonn (Germany); Gruenwald, F. [Department of Nuclear Medicine, University of Frankfurt/Main (Germany)

    2000-05-01

    The aim of this study was to evaluate the clinical use of fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) in acute and chronic osteomyelitis and inflammatory spondylitis. The study population comprised 21 patients suspected of having acute or chronic osteomyelitis or inflammatory spondylitis. Fifteen of these patients subsequently underwent surgery. FDG-PET results were correlated with histopathological findings. The remaining six patients, who underwent conservative therapy, were excluded from any further evaluation due to the lack of histopathological data. The histopathological findings revealed osteomyelitis or inflammatory spondylitis in all 15 patients: seven patients had acute osteomyelitis and eight patients had chronic osteomyelitis or inflammatory spondylitis. FDG-PET yielded 15 true-positive results. The tracer uptake correlated with the histopathological findings in each case. Bone scintigraphy performed in 11 patients yielded ten true-positive results and one false-negative result. Follow-up carried out on two patients revealed normal or clearly reduced tracer uptake, which correlated with a normalisation of clinical data. In early postoperative follow-up it was impossible to differentiate between postsurgical reactive changes and further infection using FDG-PET. It is concluded that acute and chronic osteomyelitis of the peripheral as well as the central skeleton can be detected using FDG-PET. Osteomyelitis can be differentiated from soft tissue infection surrounding the bone. Unlike computed tomography and magnetic resonance imaging, FDG-PET is not affected by metal implants used for fixing fractures. FDG-PET demonstrated promising initial results with respect to treatment monitoring. Nevertheless, in the early postoperative phase FDG-PET seems to be of limited value owing to unspecific tracer uptake. (orig.)

  20. Management & Communication: Project Management Case Study

    CERN Multimedia

    Nathalie Dumeaux

    2004-01-01

    We are pleased to announce the recent launch of a new workshop on Project Management. This is designed for People with budgetary, scheduling and/or organizational responsibilities in a project or a sub-project. The objectives through a management case study specially suited to CERN are: to become familiar with modern management techniques in use for structuring, planning, scheduling, costing and progress monitoring of a project or a sub-project. to understand in-depth issues associated with Deliverable-oriented Project Management, Earned Value Management, Advanced Project Cost Engineering and Project Risk Management. The full description of this workshop can be found here. The next session will be held on 8 October 2004. If you are interested in this workshop, please contact Nathalie Dumeaux, email or 78144. Programme of Seminars October to December 2004 Situation : 21.09.2004 Séminaires bilingues Dates Jours Places disponibles Project Management Case study 8 October 1 oui Intr...

  1. Some problems of evaluation of influence of perforation on casing string from well measurement results

    International Nuclear Information System (INIS)

    The mechanical influences on the casing are studied with instruments based on the registration of scattered γ-radiation : the γ-defectometer-thickness gauge SGDT-2 and the γ-thickness gauge. The combined measurements with both apparatuses before and after the performation allow to determine the degree of deformation and the destructions of the casing under the action of the perforation by measuring the mean thickness of the tube wall along the perimeter of the tube and its inner diameter

  2. The Graduate Experience: Living and Studying Abroad (A Case Study

    Directory of Open Access Journals (Sweden)

    Rosario Hernández Castañeda

    2008-11-01

    Full Text Available This article is a qualitative case study describing the experience of Angélica an international graduate student from Latin America, who received her doctorate at the University of New Mexico in the United States. Her case demonstrated how administrators and faculty learn about the experience and struggles endured by international students, especially those who learned English a short time before admission to graduate studies. While a single case is understandably idiographic in nature and inevitably requires a larger sample, from the analysis of Angélica’s case and the analysis of the relevant literature common topics emerged persuading me to conclude that the issues that commonly impact the life of international students have to do with: 1 second language problems; 2 the quality of academic advisement received; 3 the availability of financial support; 4 the level of integration into their academic program; and 5 the level of cultural adjustment in their host country.

  3. Gamification in teaching music : case study

    OpenAIRE

    Gomes, Cristina; Figueiredo, Mauro; Bidarra, José

    2014-01-01

    The study presented here aims to assess the quality of learning that occurred by the introduction of an educational application in the teaching/learning process of music education – 2nd cycle of basic education. The investigation focused on the use of a set of multimedia materials designed to provide support for instrumental practice (recorder and guitar) and backing vocals, according to the technique of the sing along. The students had access to the materials in two ways: in the first case, ...

  4. Case Study on Inventory Management Improvement

    OpenAIRE

    Plinere Darya; Borisov Arkady

    2015-01-01

    Inventory management is a challenging problem area in supply chain management. Companies need to have inventories in warehouses in order to fulfil customer demand, meanwhile these inventories have holding costs and this is frozen fund that can be lost. Therefore, the task of inventory management is to find the quantity of inventories that will fulfil the demand, avoiding overstocks. This paper presents a case study for the assembling company on inventory management. It is proposed to use inve...

  5. BOOK REVIEW: Case Studies in Knowledge Management

    OpenAIRE

    BOYACI, Reviewed By Dr. Adnan

    2005-01-01

    161Case Studies in Knowledge ManagementEdited by Murray JennexHersley: PA: Idea Group, 2005, pp. 372, ISBN 1-59140-352-9Reviewed by Dr. Adnan BOYACIAnadolu UniversityEskişehir-TurkeyKnowledge management (KM) as a structured system and the way to the effectiveness isrelatively new field for the contemporary organizations functioning in different andcompetitive domain of public and private sectors in terms of getting optimal effectivenessunderlined by the concepts such as quality, productivity…...

  6. Six case studies of contents tourism

    OpenAIRE

    Seaton, Philip

    2015-01-01

    This short series of research notes brings together some of the case studies that have been researched by members of the project ‘International Comparative Research on the Spreading and Reception of Culture through Contents Tourism’. This research has been funded since April 2014 by a Japan Society for the Promotion of Science grant (Kiban A, grant number 26243007). However, the project had its roots in a small group research project started in the Research Faculty of Media and...

  7. Case Study for Holylight(HK)

    OpenAIRE

    Ha, Kong Ho

    2013-01-01

    In this thesis the case company – Holylight (HK) was thoroughly studied. The company structure, business strategic management and Marketing mix (4ps) were analyzed using SWOT analysis. It was found that Holylight (HK) had huge poten-tial in the business its stable supplies from the United States of America, Europe and Australia; Alliance partnership company ensure the steady sales channel in potential market – China that further development and expansion are highly feasible. However th...

  8. Telepractice for Pediatric Dysphagia: A Case Study

    OpenAIRE

    Malandraki, Georgia A.; Melissa Roth; Justine Joan Sheppard

    2014-01-01

    A closed-ended intensive pediatric swallowing telepractice program was developed and piloted in one pediatric patient with Opitz BBB/G and Asperger’s Syndromes, oropharyngeal dysphagia and aerophagia. The present study is a case report. Outcome variables included behavioral, swallowing and quality of life variables, and were assessed at baseline and at the end of the four-week program. Selective variables were also assessed at a follow-up family interview four weeks post program completion. O...

  9. Hawaii Macadamia Nut Company- A Case Study

    OpenAIRE

    George H. (Jody) Tompson; Dan Verreault; Tompson, Holly B.

    2009-01-01

    Owners of the Hawaii Macadamia Nut Company (HMNC) are facing an expansion opportunity. A land owner has preperty available that would enable the HMNC to expand its acreage and revenue by about 20%. To fully consider this opportunity the owners must decide 1)whether the expansion is strategically and financially viable, 2)how to raise capital to finance the expansion, and 3)whether they have the skills to manage the company's growth during expansion. This is a case study describing a real comp...

  10. Private power financing: a case study

    International Nuclear Information System (INIS)

    The Public Utility Regulatory Power Act (PURPA) in the USA and the UK's Electricity Act passed in 1989 are discussed and the first UK private power project is considered. A case study is presented, and covers the questions of when to approach the bank; banker versus investment bank; project fundamentals; the sponsor and the management team; the strength of the key project agreements; syndication of the project debt; and bank support during construction and operation. (author)

  11. Customer Buying Behavior : Case Study: Algol Technics

    OpenAIRE

    Weckman, Nina

    2009-01-01

    The purpose of this study is to research the customer buying behavior in a specific market. This thesis is made for a subgroup of Algol Technics which specializes in the marketing of driver seats. The research areas included brand recognition, price and quality, as well as the communications channels. The theoretical framework presented consists of the marketing strategies, marketing mix, Porter’s five forces analysis, customer relationship marketing, and market analysis. The case compan...

  12. Marketing and clinical trials: a case study

    OpenAIRE

    Entwistle Vikki A; Snowdon Claire; Garcia Jo; Knight Rosemary C; Shakur Haleema; Elbourne Diana R; Roberts Ian; Francis David; McDonald Alison M; Grant Adrian M; Campbell Marion K

    2007-01-01

    Abstract Background Publicly funded clinical trials require a substantial commitment of time and money. To ensure that sufficient numbers of patients are recruited it is essential that they address important questions in a rigorous manner and are managed well, adopting effective marketing strategies. Methods Using methods of analysis drawn from management studies, this paper presents a structured assessment framework or reference model, derived from a case analysis of the MRC's CRASH trial, o...

  13. Case studies of soil in art

    Science.gov (United States)

    Feller, C.; Landa, E. R.; Toland, A.; Wessolek, G.

    2015-08-01

    The material and symbolic appropriations of soil in artworks are numerous and diverse, spanning many centuries and artistic traditions, from prehistoric painting and ceramics to early Renaissance works in Western literature, poetry, paintings, and sculpture, to recent developments in film, architecture, and contemporary art. Case studies focused on painting, installation, and film are presented with the view of encouraging further exploration of art about, in, and with soil as a contribution to raising soil awareness.

  14. Concentrated Photo Voltaics (CPV: a case study

    Directory of Open Access Journals (Sweden)

    Centro S.

    2015-01-01

    Full Text Available Concentrated PhotoVoltaic (CPV, among green energy solutions, nowadays has the ambition to reach grid-parity without subside. CPV substitutes large areas of expensive semiconductor solar cells, with concentrating optics made of cheap materials. Moreover the cells that are suitable for CPV exhibits an unprecedented efficiency and their technology is progressing every year. A case study project, TwinFocus®, will be presented in detail.

  15. Bilingual education in Slovakia: A Case Study

    Directory of Open Access Journals (Sweden)

    Silvia Pokrivčáková

    2013-06-01

    Full Text Available Bilingual education is one of the areas in contemporary education that brings out some important controversies (philosophical, conceptual, sociological, political, economical, etc. and thus calls for extensive and intensive debate. Bilingual education in Europe (and here the European Union countries are meant has gained a very different status, due to the general European policy of developing language diversity and promoting “European plurilingualism and multilingualism”. In Slovakia, one of the younger members of the EU, bilingual education became an extraordinarily popular instrument for the fulfilment of this task.  Since the specifically defined topic of bilingual education and its current status in Slovakia has not been studied and systematically reviewed yet, the research presented in this paper was designed as a single-phenomenon revelatory case study investigating seven research areas: reflection of bilingual education in school legislation and state pedagogical documents, purposes of bilingual education in Slovakia, its organization (levels and types of schools, foreign languages incorporated, teachers, structure of bilingual schools curricula, types of bilingual education applied at Slovak bilingual schools, and how bilingual education is both reflected in and saturated by the latest research findings. The conclusions presented in the paper were collected from multiple sources: state curriculum, statistical data published by the Slovak Ministry of Education or its partner institutions, international treaties on establishing and supporting bilingual sections of schools, bilingual schools curricula, interviews with school directors, teachers, and learners, direct observations at bilingual schools, research studies and research reports, etc. In the conclusion, bilingual education in Slovakia is identified as a unique, dynamically developing system which is both significantly shaped by the foreign language education policy promoted by

  16. Eccrine Angiomatous Hamartoma: A Retrospective Study of 15 Cases

    OpenAIRE

    Yi-Ting Lin; Chien-Ming Chen; Chih-Hsun Yang; Yea-Huey Chuang

    2012-01-01

    Background: Eccrine angiomatous hamartoma (EAH) comprises a rare nevoid proliferation of normal eccrine glands and small blood vessels and occasionally otherelements in the middle and deep dermis with variable clinical manifestations.Case series have rarely been published except for case reports and literaturereviews. The aims of this article were to investigate the clinical and pathologic features of patients with EAH in Taiwan and to compare our resultswith the results of previous studies.M...

  17. Shuttle Transportation System Case-Study Development

    Science.gov (United States)

    Ransom, Khadijah

    2012-01-01

    A case-study collection was developed for NASA's Space Shuttle Program. Using lessons learned and documented by NASA KSC engineers, analysts, and contractors, decades of information related to processing and launching the Space Shuttle was gathered into a single database. The goal was to provide educators with an alternative means to teach real-world engineering processes and to enhance critical thinking, decision making, and problem solving skills. Suggested formats were created to assist both external educators and internal NASA employees to develop and contribute their own case-study reports to share with other educators and students. Via group project, class discussion, or open-ended research format, students will be introduced to the unique decision making process related to Shuttle missions and development. Teaching notes, images, and related documents will be made accessible to the public for presentation of Space Shuttle reports. Lessons investigated included the engine cutoff (ECO) sensor anomaly which occurred during mission STS-114. Students will be presented with general mission infom1ation as well as an explanation of ECO sensors. The project will conclude with the design of a website that allows for distribution of information to the public as well as case-study report submissions from other educators online.

  18. 颈前路经椎间隙减压盒状cage植骨融合术治疗单间隙颈椎病-附86例随访结果%Study on clinical results of single - level cervical discectomy and box - shape bone graft fusion in treatment of single - level cervical disease. A report of results in follow - up study of 86 cases.

    Institute of Scientific and Technical Information of China (English)

    唐拥军; 曾凡伟; 池雷霆

    2011-01-01

    目的 观察经颈前路椎间隙减压盒状椎体护架(cage)植融合术治疗单间隙颈椎病的结果.方法 选择86例患者应用盒状Cage行颈前路减压,植骨融合术治疗单间隙颈椎病,随访3个月至4年.结果 神经功能恢复率为86.0%(GDA评分),所有患者术后CT证实融合,术后并发症发生率7.0%.结论 经颈前路椎间隙减压盒状Cage植骨融合术治疗单间隙颈椎病,目前已成为公认的最佳术式之一.%Objective To observe the effectiveness and prognosis of anterior approach for decompression and bone - graft fusion in treatment of patients with cervical spondylosis. Methods Altogether 86 cases of cervical spondylosis were treated with anterior approach decompression and bone - graft fusion. All these cases were followed up for 3 to 4 months. Results The rate of symptomatic relief is 86% ( by JOA scores ),and all these cases are proved to be getting fusion by CT scanning. The rate of occurrence of complications is 7% ( 6 cases ). Conlusion The anterior approach for decompression and titanium cage bone - graft fusion are considered to be the best method for treatment of patients with cervical spondylosis.

  19. [The anal incontinence-- study on 20 operated cases].

    Science.gov (United States)

    Iusuf, T; Sârbu, V; Grasa, C; Cristache, C; Botea, F

    2001-01-01

    The authors present 20 cases operated for anal incontinence. Two techniques were performed: direct repair (18 cases) and Musset-Cottrell procedure (2 cases). The results were excellent in 12 cases, good in 5 cases and satisfactory in 3 cases. The method of choice seems to be the direct repair of the anal sphincter after a proper local and general preparation. PMID:12731180

  20. A retrospective study of nine cases of Acanthamoeba keratitis

    Directory of Open Access Journals (Sweden)

    Tetsuya Mutoh

    2010-10-01

    Full Text Available Tetsuya Mutoh, Isao Ishikawa, Yukihiro Matsumoto, Makoto ChikudaDokkyo Medical University Koshigaya Hospital, Saitama, JapanPurpose: To evaluate the clinical features of Acanthamoeba keratitis in nine patients diagnosed at Dokkyo Medical University Koshigaya Hospital, Saitama, Japan.Methods: In nine eyes of nine patients, Acanthamoeba keratitis was diagnosed by direct light microscopy of corneal scrapings stained by the Parker ink-potassium hydroxide method between September 2006 and September 2009. Their clinical features and course were studied retrospectively. Antifungal eye drops, systemic antifungal therapy, and surgical debridement of the corneal lesions were performed in all patients.Results: At presentation, the clinical stage was initial in six cases, transient in one case, and complete in two cases. The patients were all contact lens wearers who had washed their lens storage cases with tap water. After treatment, final visual acuity was improved in six cases, unchanged in one case, and worse in two cases. The patient with the worst final vision (hand motion had rheumatoid arthritis and was taking oral prednisolone, which led to corneal perforation and prevented adequate debridement from being done.Conclusion: Acanthamoeba keratitis is closely related to wearing contact lenses and washing the lens storage case with tap water. Although final visual acuity improved after treatment in most patients, insufficient surgical debridement resulted in a poor visual prognosis.Keywords: surgical debridement, Acanthamoeba keratitis, contact lens wearers

  1. Mucocele - A study of 36 cases

    Directory of Open Access Journals (Sweden)

    Jani Dhaval

    2010-01-01

    Full Text Available Background: Mucocele is one of the most common benign soft tissue tumor present in the oral cavity. They are of two types - one is extravasation and second one is retention type but the majority are extravasation type. Aims: The objective is to determine various factors related to mucocele such as role of trauma due to nearby teeth, recurrence, duration, and to find out whether there is any role of psychological stress which initiates trauma like lip or cheek biting. Materials and Methods: 36 cases of mucocele diagnosed at the Department of the Oral Pathology, Govt. Dental College and Hospital, Ahmedabad, between 2004 and 2008 were reviewed. The clinical data were recorded and histopathologic diagnosis was made. Statistical Analysis Used: Data analysis tool, Microsoft Office Excel 2007. Results: A diagnosis of mucocele was established in 36 cases with male-to-female ratio of 1.77:1. Most common type was extravasation in 30 (83.33% cases. The peak age of occurrence was between 1st and 3rd decade. Lateral side of the lower labial mucosa was the most affected site in 34 (94.44% cases. The history of trauma appeared the major etiological factor seen in 28 (77.77% cases. Conclusion: We conclude that there was male predominance and they were more affected in 2nd and 3rd decade. The lateral side of lower labial mucosa was the commonest site and the trauma due to teeth or lip biting was the major etiological factor for the occurrence of the mucocele. The article highlights role of psychological stress in occurrence of mucocele. The reader should understand the importance of histopathology examination and should try to control the psychological stress in such mucocele patients.

  2. Capturing Cultural Glossaries: Case-study II

    Directory of Open Access Journals (Sweden)

    Matete Madiba

    2011-10-01

    Full Text Available

    ABSTRACT: This case-study attempts to present a brief glossary of Northern Sotho medical terms. It is a follow-up of a similar case-study (Madiba, Mphahlele and Kganyago 2003, which was an attempt to capture and present Northern Sotho cooking terms. Case-study I consists of the names for utensils, ingredients and the processes involved in the preparation of cultural dishes. With both these case-studies, the intention has been to use the opportunities availing themselves for the pres-ervation and valorisation of Northern Sotho, including the extension of its corpora to support national dictionary-making processes. The case-study methodology has been very useful for the purposes of this project and the context within which it was undertaken. It aims to provide a model for the collection and presentation of authentic Northern Sotho terminology which otherwise would hardly have been accessible.

    Keywords: CULTURAL GLOSSARY, INDIGENOUS KNOWLEDGE SYSTEMS, CORPUS, OUTCOMES-BASED EDUCATION, ASSESSMENT CRITERIA, TRADITIONAL MEDICAL TERMS, COMMUNICATIVE APPROACH, STRUCTURAL APPROACH, METONYMY, HANDS-ON ACTIVITIES, TASK-BASED LEARNING

    *****

    OPSOMMING: Die totstandbrenging van kulturele woordversamelings: Ge-vallestudie II. Hierdie gevallestudie probeer om 'n beperkte woordelys van Noord-Sotho- mediese terme aan te bied. Dit is 'n voortsetting van 'n soortgelyke gevallestudie (Madiba, Mpha-hlele en Kganyago 2003 wat 'n poging was om Noord-Sothokookterme te versamel en aan te bied. Gevallestudie I bestaan uit die name van gereedskap, bestanddele, en die prosesse betrokke by die voorbereiding van kulturele geregte. Met altwee hierdie gevallestudies was die bedoeling om die geleenthede te gebruik wat hulleself aanbied vir die bewaring en bestendiging van Noord-Sotho, insluitende die uitbreiding van sy korpora om die nasionale woordeboeksamestellingsprosesse te ondersteun. Die gevallestudiemetodologie was baie nuttig vir die doeleindes van

  3. Results of titanium elastic nailing in paediatric femoral diaphyseal fractures— report of 30 cases

    Institute of Scientific and Technical Information of China (English)

    Divesh Jalan; Rajesh Chandra; VK Sharma

    2013-01-01

    Objective:Fractures of the femur are the most incapacitating fractures.For children aged 6-14 years,there is no clear consensus as to the preferred treatment.The conventional treatment of traction and casting is no longer recommended.We report our experience in titanium elastic nailing for treatment of paediatric femoral diaphyseal fractures.Methods:Thirty patients in the age group of 6-16 years with displaced diaphyseal femoral fractures were stabilized with titanium elastic nails.Patients were followed up clinically and radiologically for a minimum period of 1 year.The final results were evaluated using Flynn's criteria.Technical difficulties and complications associated with the procedure were also analysed.Results:Overall results were excellent in 20 cases and satisfactory in 10 cases.No patient had poor result.The average hospital stay was 9 days.All the fractures healed with an average time to union of 6.86 weeks.The most common complication encountered was soft tissue irritation at the nail entry site seen in 6 cases.Clinically,lengthening was noticed in 4 cases,while no patient had shortening.Malalignment was seen in only 6 cases.Perioperative difficulties encountered were failure of closed reduction seen in 6 cases and corkscrewing of nails in one case.Conclusion:Titanium elastic nails are a relatively easy to use,minimally invasive,physeal-protective implant system with high rate of good and excellent outcomes in children aged 6-16 years.Technical pitfalls can be eliminated by adhering to the basic principles.

  4. Results of titanium elastic nailing in paediatric femoral diaphyseal fractures-report of 30 cases

    Directory of Open Access Journals (Sweden)

    Jalan Divesh

    2013-04-01

    Full Text Available 【Abstract】 Objective: Fractures of the femur are the most incapacitating fractures. For children aged 6-14 years, there is no clear consensus as to the preferred treatment. The conventional treatment of traction and cast-ing is no longer recommended. We report our experience in titanium elastic nailing for treatment of paediatric femoral diaphyseal fractures. Methods: Thirty patients in the age group of 6-16 years with displaced diaphyseal femoral fractures were sta-bilized with titanium elastic nails. Patients were followed up clinically and radiologically for a minimum period of 1 year. The final results were evaluated using Flynn’s criteria. Tech-nical difficulties and complications associated with the pro-cedure were also analysed. Results: Overall results were excellent in 20 cases and satisfactory in 10 cases. No patient had poor result. The average hospital stay was 9 days. All the fractures healed with an average time to union of 6.86 weeks. The most com-mon complication encountered was soft tissue irritation at the nail entry site seen in 6 cases. Clinically, lengthening was noticed in 4 cases, while no patient had shortening. Malalignment was seen in only 6 cases. Perioperative diffi-culties encountered were failure of closed reduction seen in 6 cases and corkscrewing of nails in one case. Conclusion: Titanium elastic nails are a relatively easy to use, minimally invasive, physeal-protective implant sys-tem with high rate of good and excellent outcomes in chil-dren aged 6-16 years. Technical pitfalls can be eliminated by adhering to the basic principles. Key words: Titanium; Nails; Fractures, bone; Femur; Paediatrics

  5. Assessment of global phase uncertainty in case-control studies

    Directory of Open Access Journals (Sweden)

    van Houwelingen Hans C

    2009-09-01

    Full Text Available Abstract Background In haplotype-based candidate gene studies a problem is that the genotype data are unphased, which results in haplotype ambiguity. The measure 1 quantifies haplotype predictability from genotype data. It is computed for each individual haplotype, and for a measure of global relative efficiency a minimum value is suggested. Alternatively, we developed methods directly based on the information content of haplotype frequency estimates to obtain global relative efficiency measures: and based on A- and D-optimality, respectively. All three methods are designed for single populations; they can be applied in cases only, controls only or the whole data. Therefore they are not necessarily optimal for haplotype testing in case-control studies. Results A new global relative efficiency measure was derived to maximize power of a simple test statistic that compares haplotype frequencies in cases and controls. Application to real data showed that our proposed method gave a clear and summarizing measure for the case-control study conducted. Additionally this measure might be used for selection of individuals, who have the highest potential for improving power by resolving phase ambiguity. Conclusion Instead of using relative efficiency measure for cases only, controls only or their combined data, we link uncertainty measure to case-control studies directly. Hence, our global efficiency measure might be useful to assess whether data are informative or have enough power for estimation of a specific haplotype risk.

  6. Case studies in atomic collision physics

    CERN Document Server

    McDaniel, E W

    2013-01-01

    Case Studies in Atomic Collision Physics II focuses on studies on the role of atomic collision processes in astrophysical plasmas, including ionic recombination, electron transport, and position scattering. The book first discusses three-body recombination of positive and negative ions, as well as introduction to ionic recombination, calculation of the recombination coefficient, ions recombining in their parent gas, and three-body recombination at moderate and high gas-densities. The manuscript also takes a look at precision measurements of electron transport coefficients and differential cr

  7. A CASE STUDY ON MEASUREMENT EFFECTIVENESS

    Directory of Open Access Journals (Sweden)

    Vladimír Modrák

    2007-03-01

    Full Text Available Ensuring the measurement effectiveness of Cost of Quality (COQ implementations presents steadily a practical managerial problem. Even though there are many approaches to measurement COQ optimal methods for this purpose in real conditions often depend on confrontation and evaluation of different calculation models. The paper based on a case study describes a procedure for comparison between so called controllable costs and incurred cost of poor quality. Presented study confirms assumption of a propitious influence of preventive costs on an overall COQ and a change of structure of separate cost of quality items.

  8. Using Case Studies to Teach About Global Issues, Bali: A Case Study

    Science.gov (United States)

    Oswald, James M.

    1974-01-01

    The South Pacific island of Bali is used as a case study of overpopulation and food shortage. A brief description of the resources, the typical lifestyle of the Balinese farmer, and possible teaching techniques are given. (DE)

  9. Delusional parasitosis--study of 3 cases.

    Directory of Open Access Journals (Sweden)

    Hanumantha K

    1994-10-01

    Full Text Available Delusional disorder-somatic (parasitosis type is a rare psychiatric disorder which poses a challenge to diagnostic and therapeutic skills. Pimozide, a highly specific dopamine blocker has shown promising results in the 3 cases illustrated here. These cases were seen over a period of 3 years. All the three patients believed that an insect has entered through the ear and is burrowing tracts/laying multiple eggs. They approached the ENT surgeons or neurosurgeon with a fear that their brain will be invaded. On psychiatric evaluation, no past or present history of major psychiatric illness was found. Premorbid personalities were well adjusted. Only for two patients, acute moderate stressors were detected. Delusions disappeared by the end of 2 wks but therapy was continued for 5 months.

  10. The case study of biomaterials and biominerals

    Science.gov (United States)

    Del Hoyo Martínez, Carmen

    2013-04-01

    The teaching of biomaterials as case study by on-line platform , susceptible to develop both individually and in groups, got different objectives proposed by the European Higher Education System, among which include: participate actively in the teaching-learning process by students, interpreting situations, adapt processes and solutions. It also improves oral and written communication, analytical skills and synthesis and also the ability to think critically. Biomaterials have their origin in biominerals. These are solid inorganic compounds of defined structure, consisting of molecular control mechanisms that operate in biological systems. Its main functions are: structural support, a reservoir of essential elements, sensors, mechanical protection and storage of toxic elements. Following the demand of materials compatible with certain functional systems of our body, developed biomaterials. Always meet the condition of biocompatibility. Should be tolerated by the body and do not provoke rejection. This involves a comprehensive study of physiological conditions and the anatomy of the body where a biomaterial has to be implemented. The possibility of generating new materials from biominerals has a major impact in medicine and other fields could reach as geology, construction, crystallography, etc. While the study of these issues is in its infancy today, can be viewed as an impact on the art and future technology. Planning case study that students would prepare its report for discussion in subgroups. Occurs then the pooling of individual analysis, joint case discussion and adoption by the subgroup of a consensual solution to the problem. The teacher as facilitator and coordinator of the final case analysis, sharing leads to group-wide class and said the unanimous decision reached by the students and gives his opinion on the resolution of the case. REFERENCES D.P. Ausubel. Psicología Educativa. Un punto de vista cognoscitivo. Trillas. Ed. 1983. E.W. Eisner. Procesos

  11. HOW TO DESCRIBE THE RESULTS OF OBSERVATIONAL EPIDEMIOLOGICAL STUDIES

    Directory of Open Access Journals (Sweden)

    S. A. Shal'nova

    2016-01-01

    Full Text Available Principles and fundamentals of proper presentation of observational epidemiological study results are focused. Principles of observational study publication developed by expert epidemiologists (STROBE statement are explained in detail.

  12. A Textbook Evaluation of Speech Acts: The Case of English Result Series

    Directory of Open Access Journals (Sweden)

    Minoo Alemi

    2012-11-01

    Full Text Available The present work aimed to investigate the frequency of occurrences and proportions of speech acts of complaints and compliments in the four volumes of the course book English Result (Elementary, Pre-intermediate, Intermediate, and Upper-intermediate, by Mark Hancock and Annie McDonald (2009, published by Oxford University Press. Investigation of the two speech act strategies was based on complaints strategies (Olshtain and Weinbach, 1987 and compliment strategies (Wolfson and Manes, 1981. It was found that the books were rich in terms of the number of the two speech acts, but in presenting them, there were one or two dominant strategies in both cases. Chi-square analysis demonstrated that there was a significant difference in the proportion of complaint and compliment strategies through the four course books. In general, the books were reported to provide learners with adequate amount of complaints and compliments, but with low variations in strategy types, which may result in learners not having sufficient conceptual and practical knowledge of speech acts to use them appropriately in different contexts. Based on the findings of this study, it seems necessary to incorporate more authentic and helpful instruction of speech acts along with the course books, to improve the learners’ performance in real life communication.Keywords: Course book evaluation, Speech acts, speech acts strategies, Complaints, Compliments

  13. Working conditions and mental health: Results from the CARESUN study.

    Science.gov (United States)

    Feola, Daniela; Pedata, Paola; D'Ancicco, Francesco; Santalucia, Laura; Sannolo, Nicola; Ascione, Eduardo; Nienhaus, Albert; Magliano, Lorenza; Lamberti, Monica

    2016-05-01

    The authors conducted a work-related stress surveillance study in 2013 on 6,558 public-sector employees in Italy, examining how they perceived their jobs, via the Job Content Questionnaire, and their mental health status, via the General Health Questionnaire 12 (GHQ-12). Of the 2,094 employees completing the questionnaires, 60% were male, 52% had a medium-level education, and 76% had a medium-level job. Three hundred and eighty-five employees (18%) had a GHQ-12 score >3 and were classified as GHQ-12 cases: these were more often female (54%), medium-to-highly educated (54%), and had more often reported health problems over the previous year (51%). Thus, GHQ-12 cases represented a significant percentage of the examined population, indicating that work-related stress surveillance programs are needed for the planning of psychosocial interventions aimed at the reintegration of individuals with mental health problems. PMID:26167870

  14. Characterizing dense suspensions: two case studies from the pharmaceutical industry

    Science.gov (United States)

    Goldfarb, David J.; Khawaja, Nazia; Kazakevich, Irina; Bhattacharjee, Himanshu; Heslinga, Michael; Dalton, Chad

    2015-11-01

    Liquid suspensions of Active Pharmaceutical Ingredient powders are present as pharmaceutical dosage forms in the form of oral suspensions and injectables. We present two case studies, both dense (~ 30-40%) suspensions, in which the physical characterization of the product, specifically, particle size & shape and rheology were key to understanding the key product attributes as pertaining to the manufacturing process and to patient administration. For the one case study, an oral suspension, identifying variations in particle morphology during the wet milling of the product was key to the product understanding necessary to modify the milling process. Rheological measurements were applied as well. For the second case study, an injectable, results from different particle size measurement techniques and rheological measurements indicated the possibility of flocculation in a formulation. Additionally, measurements were obtained to assess the ``injectability'' of the product via rheometer and texture analyzer measurements and Poiseuille flow modeling. As a result, the relevant shear rate regime for this drug product administration was identified.

  15. Forecast Master Program case studies: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Engle, R.; Granger, C.; Ramanathan, R. (ed.)

    1987-04-01

    This report presents a number of case studies using the computer software package FORECAST MASTER (FM). The series studied and forecast are, aggregate monthly California Electricity Sales, system energy demand data from Ontario Hydro, peak demand data for the residential and commercial customers of Georgia Power Company, Massachusetts Electric commercial sales, Narragansett Electric commercial sales, average and peak demand using Georgia Power Company data. A variety of methods have been studied by each of the contributing authors; trend line fitting, exponential smoothing, Box-Jenkins univariate forecasting, vector autoregression, state space modeling, dynamic econometric models including time-varying parameters and general order serial correlation corrections. Thus both the data sets and the modeling/forecasting methodologies are varied. A number of conclusions emerge from these case studies: FM provides a powerful set of tools to aid a utility forecaster, a great deal of caution should be exercised in pre-processing the data; it can have unintended side effects, diagnostic tests are very useful in econometric models, the Akaike Information Criterion is a useful measure for selecting the best state space model, and state space and econometric approaches both need equal amounts of care in model analysis and presentation.

  16. A fenestration approach to arytenoid adduction for unilateral vocal cord paralysis. Results of 32 cases

    International Nuclear Information System (INIS)

    The objective of this study was to develop and evaluate the voice outcomes of an approach to arytenoid adduction (AA) for unilateral vocal cord paralysis through fenestration of the thyroid ala. Thirty-two patients with unilateral vocal cord paralysis underwent laryngoplasty using an approach to AA performed through fenestration of the thyroid ala combined with type I thyroplasty. Thirty-two patients with unilateral vocal cord paralysis were treated between October 2004 and February 2008. In all cases, maximum phonation time (MPT) and mean airflow rate (MFR) were measured before and after the operation. The voices were analyzed using shimmer and jitter. Two surgical windows were made in the lower part of the thyroid ala. The anterior one was for typical type I thyroplasty and the posterior one was for arytenoid adduction (AA). The locations of the two windows were determined based on three-dimensional computer tomography (3DCT) data. AA was performed by muscular process through the posterior window without releasing the cricothyroid joint. The operations were performed under local anesthesia with sedation. Vocal cord medialization was confirmed endoscopically during the operation. Twenty-nine of the 32 patients achieved an MPT of over 10 s after surgery. The other 3 cases, whose MPTs were 9 s after the operation, had low breathing capacity because of lung disease and normal side vocal cord sulcus. The MFRs, which ranged from 236 to 1908 ml/s before the operation, improved to under 200 ml/s except in 3 patients, whose MFRs were 210 ml/s, 214 ml/s and 216 ml/s. Jitter and shimmer improved significantly after the operation. Perceptual evaluation using the GRBAS scale also improved significantly. Our new procedure simplified the combination of AA and type I thyroplasty because the two treatments can be performed in the same operating field, obtaining good voice improvement. Determination of the surgical approach using 3DCT and endoscopic vocal cord observation may

  17. ALTERNATIVE AND ENHANCED CHEMICAL CLEANING: BASIC STUDIES RESULTS FY2010

    Energy Technology Data Exchange (ETDEWEB)

    King, W.; Hay, M.

    2011-01-24

    is possible with the addition of a supplemental hydrogen ion source (HNO{sub 3} or H{sub 2}SO{sub 4}) and pH control. (5) Sulfuric acid is nearly twice as effective as nitric acid (on a molar basis) at promoting hematite dissolution in oxalic acid solutions, most likely due to the fact that it is diprotic. (6) The greater the oxalic acid concentration, the greater the demand for supplemental H{sup +} to promote optimal dissolution. Minimum mineral acid concentrations required for optimal oxalic acid utilization based on hematite solubility tests are provided. (7) Corrosion studies conducted (reported elsewhere) with 1 wt.% oxalic acid revealed that carbon steel corrosion rates are manageable at lower mineral acid concentrations (0.1 M HNO{sub 3} and 0.05 M H{sub 2}SO{sub 4}) and lower temperatures (45 C). (8) Proposed conditions for waste tank heel dissolution based on the solubility and corrosion test results are 0.5 wt.% oxalic acid and 0.18 M HNO{sub 3} or 0.09 M H{sub 2}SO{sub 4} at 50 C. (9) The OLI Thermodynamic Model appears to over-predict the solubility of the iron phases studied in oxalic acid and oxalic/nitric acid mixtures. The predictions show better agreement with experimental results at higher pH and in sulfuric/oxalic acid mixtures. (10) Oxalic, nitric, and sulfuric acids are effective at quickly dissolving gibbsite ({ge}86% dissolution in 2 weeks), with oxalic/sulfuric acid mixtures being particularly effective. (11) Limited dissolution tests conducted with carbon steel coupons revealed that the presence of metallic iron can, in some cases, result in dramatically different results. Additional studies in this area are recommended. Based on the current results, the optimal approach for the removal of sludge heels for HLW tanks would include the following steps: (1) removal of the maximum possible amount of heel materials by mechanical means; (2) neutralization and acidification of the heel using dilute mineral acid (This step should promote significant

  18. ALTERNATIVE AND ENHANCED CHEMICAL CLEANING: BASIC STUDIES RESULTS FY2010

    Energy Technology Data Exchange (ETDEWEB)

    King, W.; Hay, M.

    2011-01-24

    is possible with the addition of a supplemental hydrogen ion source (HNO{sub 3} or H{sub 2}SO{sub 4}) and pH control. (5) Sulfuric acid is nearly twice as effective as nitric acid (on a molar basis) at promoting hematite dissolution in oxalic acid solutions, most likely due to the fact that it is diprotic. (6) The greater the oxalic acid concentration, the greater the demand for supplemental H{sup +} to promote optimal dissolution. Minimum mineral acid concentrations required for optimal oxalic acid utilization based on hematite solubility tests are provided. (7) Corrosion studies conducted (reported elsewhere) with 1 wt.% oxalic acid revealed that carbon steel corrosion rates are manageable at lower mineral acid concentrations (0.1 M HNO{sub 3} and 0.05 M H{sub 2}SO{sub 4}) and lower temperatures (45 C). (8) Proposed conditions for waste tank heel dissolution based on the solubility and corrosion test results are 0.5 wt.% oxalic acid and 0.18 M HNO{sub 3} or 0.09 M H{sub 2}SO{sub 4} at 50 C. (9) The OLI Thermodynamic Model appears to over-predict the solubility of the iron phases studied in oxalic acid and oxalic/nitric acid mixtures. The predictions show better agreement with experimental results at higher pH and in sulfuric/oxalic acid mixtures. (10) Oxalic, nitric, and sulfuric acids are effective at quickly dissolving gibbsite ({ge}86% dissolution in 2 weeks), with oxalic/sulfuric acid mixtures being particularly effective. (11) Limited dissolution tests conducted with carbon steel coupons revealed that the presence of metallic iron can, in some cases, result in dramatically different results. Additional studies in this area are recommended. Based on the current results, the optimal approach for the removal of sludge heels for HLW tanks would include the following steps: (1) removal of the maximum possible amount of heel materials by mechanical means; (2) neutralization and acidification of the heel using dilute mineral acid (This step should promote significant

  19. STUDY OF MATERNAL AND PERINATAL OUTCOME IN REFERRED OBSTETRICS CASES

    Directory of Open Access Journals (Sweden)

    Umesh

    2015-03-01

    Full Text Available OBJECTIVE: To review the referred obstetric cases for reason of referral and to study the maternal and perinatal outcome. DESIGN: Prospective Observational study . STUDY POPULATION: 380 cases referred from periphery to tertiary care institute in one year duration. METHODS: INCLUSION C RITERIA : All referred ANC cases to our tertiary care institute >20 weeks gestation. The total number of deliveries during this period were 11106. The total number of referred cases in above study period was 1980. Out of these 1520 met the inclusion criteria & according to the sample size calculated 380 cases were selected for the study. Selection of cases were done by systematic sampling technique. RESULTS: The proportion of referral cases to the tertiary care institute is 17.83%. Majority (42.37% of referred cases were from district level hospitals showing lacunae in the emergency obstetric care given at the district level hospitals. In present study, there was unavailability of ambulance in 65.26% of cases for transport. Most (92.89% of the patients were not accompanied by any medical assistance during transport. Major complication during immediate postpartum period was postpartum hemorrhage (19.99%. In our study, 31.84% of the patients required blood/blood products transfusion. There were 3(0.79% maternal mortalities in present study & behind these there were total 70(18.42% near miss cases which provide valuable information on the quality of antenatal care at the periphery. 54.87% of all neonates had low birth weight in this study. In present study, 45.90% babies were p reterm. Total NICU admission rate was 14.36%. Neonatal mortality documented in present study was 5.38%. CONCLUSION: The present study has shown that improper antenatal & intranatal care at the periphery level is responsible for poor maternal & perinatal outcome. Rural women have very poor access to MCH services. There is lack of Transportation facilities for referral patients & they have to

  20. Decreasing suprapubic tube-related injuries: results of case series and comprehensive literature review.

    Science.gov (United States)

    Tompkins, Andrew J; Travis, Michelle; Watne, Reed E; Lasser, Michael; Ellsworth, Pamela

    2014-01-01

    Bowel-related injuries are known complications of suprapubic tube (SPT) catheterization placement. A literature review was conducted to determine identifiable risk factors for bowel injury. Results on the analysis of 25 cases are presented along with a proposed algorithm to aid in choosing between open, percutaneous, and image-guided methods of placement. PMID:24716375

  1. Tracheoesophageal fistula resulting from invasive aspergillosis in acute lymphoblastic leukemia: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Si Won [Daejeon St. Mary' s Hospital, College of Medicine, Catholic University, Daejeon (Korea, Republic of)

    2006-04-15

    Tracheoesophageal fistula (TEF) in adult patients is an uncommon complication in leukemia. We present here on a case of TEF in a 46-year-old woman with ALL. The patient was asymptomatic and TEF is resulted from aspergillus bronchitis during the chemotherapy for acute lymphoblastic leukemia (ALL)

  2. Tracheoesophageal fistula resulting from invasive aspergillosis in acute lymphoblastic leukemia: a case report

    International Nuclear Information System (INIS)

    Tracheoesophageal fistula (TEF) in adult patients is an uncommon complication in leukemia. We present here on a case of TEF in a 46-year-old woman with ALL. The patient was asymptomatic and TEF is resulted from aspergillus bronchitis during the chemotherapy for acute lymphoblastic leukemia (ALL)

  3. Wind to Hydrogen in California: Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Antonia, O.; Saur, G.

    2012-08-01

    This analysis presents a case study in California for a large scale, standalone wind electrolysis site. This is a techno-economic analysis of the 40,000 kg/day renewable production of hydrogen and subsequent delivery by truck to a fueling station in the Los Angeles area. This quantity of hydrogen represents about 1% vehicle market penetration for a city such as Los Angeles (assuming 0.62 kg/day/vehicle and 0.69 vehicles/person) [8]. A wind site near the Mojave Desert was selected for proximity to the LA area where hydrogen refueling stations are already built.

  4. Case Study of the California Cement Industry

    OpenAIRE

    Coito, Fred; Powell, Frank; Worrell, Ernst; Price, Lynn; Friedmann, Rafael

    2005-01-01

    California is the largest cement producing state in the U.S., accounting for between 10 percent and 15 percent of U.S. cement production and cement industry employment. The cement industry in California consists of 31 sites that consume large amounts of energy, annually: 1,600 GWh of electricity, 22 million therms of natural gas, 2.3 million tons of coal, 0.25 tons of coke, and smaller amounts of waste materials, including tires. The case study summarized in this paper focused on providi...

  5. Centralized vs. Distributed Databases. Case Study

    Directory of Open Access Journals (Sweden)

    Nicoleta Magdalena Iacob

    2015-12-01

    Full Text Available Currently, in information technology domain and implicit in databases domain can be noticed two apparently contradictory approaches: centralization and distribution respectively. Although both aim to produce some benefits, it is a known fact that for any advantage a price must be paid. In addition, in this paper we have presented a case study, e-learning portal performance optimization by using distributed databases technology. In the stage of development in which institutions have branches distributed over a wide geographic area, distributed database systems become more appropriate to use, because they offer a higher degree of flexibility and adaptability then centralized ones.

  6. Case Study Method in Business Education in the USA

    Directory of Open Access Journals (Sweden)

    Velushchak Maryna

    2014-12-01

    Full Text Available Business Education is dynamic in nature and needs diverse information to deal with different business problems. To understand the peculiar situations and to manage them effectively, case studies are widely used. Researchers in education have already demonstrated that students' active participation in the educational process increases their learning outcomes. Methods of small group activities, case studies and cooperative student projects give the opportunity to participate actively in the learning process by talking, reading, writing and reflecting. Case-based learning is an essential part of business education as it enables students to discover and develop their unique framework for dealing with business problems. The important peculiarity of the business case study is that it introduces a slice of realism into the learning experience. The case study method helps the students in developing wisdom and gives lot of scope for knowledge application. Nowadays, business education should be much more practically oriented and has to consider the main features of a modern competitive global economy. Lectures and discussions are not any more the most effective teaching methods. As research results show, the case method is the most effective teaching technique of future career preparations and practical application skills in today's business environment as it enables students examining different business situations in various cultural and economic perspectives, opening up their minds by solving the problems of the real business situations.

  7. FUNMIG Integrated Project results and conclusions from a safety case perspective

    International Nuclear Information System (INIS)

    The scope of the FUNMIG Integrated Project (IP) was to improve the knowledge base on biogeochemical processes in the geosphere which are relevant for the safety of radioactive waste repositories. An important part of this project involved the interaction between data producers (research) and data users (radioactive waste management organisations in Europe). The aim thereof was to foster the benefits of the research work for performance assessment (PA), and in a broader sense, for the safety case of radioactive waste repositories. For this purpose a specifically adapted procedure was elaborated. Thus, relevant features, events and processes (FEPs) for the three host rock types, clay, crystalline and salt, were taken from internationally accepted catalogues and mapped onto each of the 108 research tasks conducted during the FUNMIG project by a standardised procedure. The main outcome thereof was a host-rock specific tool (Task Evaluation Table) in which the relevance and benefits of the research results were evaluated both from the PA and research perspective. Virtually all generated data within FUNMIG are related to the safety-relevant FEP-groups “transport mechanisms” and “retardation”. Generally speaking, much of the work within FUNMIG helped to support and to increase confidence in the simplified PA transport and retardation models used for calculating radionuclide (RN) transport through the host rock. Some of the studies on retardation processes (e.g. coupled sorption-redox processes at the mineral–water interface) yielded valuable data for all three rock types dealt within the IP. However, most of the studies provided improved insight regarding host-rock specific features and processes, the majority of this work being dedicated to clay-rich and crystalline host rocks. For both of these host rock types, FUNMIG has significantly contributed to improving understanding on a conceptual level, both by providing new experimental data at different spatial

  8. RELATIONSHIP OF SUCCESS IN UNIVERSITY STUDY AND ADMISSION EXAM RESULTS

    OpenAIRE

    Poláčková, Julie

    2013-01-01

    The admission examinations represent a first important moment in academic education. If the admission proceedings really are expected to satisfy the intention to select those most capable and fittest candidates for study, proper attention has to be paid to them. Besides checking and confirming satisfactory levels of the results of secondary school studies they also should predict with sufficient reliability the academic success of study in the given branch. The paper brings research results c...

  9. Mucocele in lower lip as a result of improper use of feeding bottle: a case report.

    Science.gov (United States)

    Ashok Kumar, S; Ramakrishnan, Mahesh

    2013-01-01

    A rare case of mucocele associated with improper feeding habit has been presented. An eight-month old male child presented with swelling in lower lip which was noticed by his mother a week earlier. A thorough clinical examination and history taking gave a diagnosis of mucocele resulting from improper use of feeding bottle. This case highlights and discusses the history, the clinical along with histologic features, and the clinical management of this lesion. Awareness of such an entity and the functional problems associated with the lesion will help the pediatric dentist to prevent any further complications. PMID:23573429

  10. Mucocele in Lower Lip as a Result of Improper Use of Feeding Bottle: A Case Report

    Directory of Open Access Journals (Sweden)

    S. Ashok Kumar

    2013-01-01

    Full Text Available A rare case of mucocele associated with improper feeding habit has been presented. An eight-month old male child presented with swelling in lower lip which was noticed by his mother a week earlier. A thorough clinical examination and history taking gave a diagnosis of mucocele resulting from improper use of feeding bottle. This case highlights and discusses the history, the clinical along with histologic features, and the clinical management of this lesion. Awareness of such an entity and the functional problems associated with the lesion will help the pediatric dentist to prevent any further complications.

  11. Antenatal stress: An Irish case study.

    LENUS (Irish Health Repository)

    Carolan-Olah, Mary

    2013-05-16

    BACKGROUND:: stress in pregnancy is common and impacts negatively on women, infants and families. A number of factors contribute to high levels of stress in pregnancy, including financial concerns, marital discord, low support systems and low socio-economic status. OBJECTIVES:: the aim of this study was to evaluate stress anxiety levels and depressive symptoms among low risk women in an area in Ireland that was particularly impacted by the 2008 economic crisis. DESIGN:: a quantitative descriptive cross-sectional design was used. Data were collected using the Edinburgh Postnatal Depression Scale (EPDS), the Perceived Stress Scale and the State Trait Anxiety Inventory (STAI). Data was collected at a single time during the second trimester. SETTING:: this paper reports a case study of one maternity service in Ireland. Participants included low risk pregnant women who were attending the hospital clinic for routine antenatal care. RESULTS:: of 150 questionnaires distributed, 74 completed questionnaires were returned indicating a 49.3% return rate. Findings indicated high levels of stress, anxiety and depressive symptomatology among participants. There were no significant difference in mean EPDS score for different age groups (F4,69=2.48, P=0.052), living arrangements (F4,68=0.90, P=0.5) or usual occupation (F4,69=1.45, P=0.2). A score of ≥12 was taken as indicative of probable antenatal depression and 86.5% of participants responded with a score of 12 or above. PSS scores were also high and more than three quarters of respondents scored ≥15 (75.6%) and more than a third had scores ≥20 (35.1%), out of a total score of 40. There was a significant difference in mean PSS score between the different age groups (F4,69=3.60, P=0.010) but not for living arrangements or usual occupation. A STAI score of ≥39 was taken as indicative of antenatal anxiety, and 74.3% of participants responded with a score of 39 or above. There were no significant differences in mean STAI

  12. Methodology and results of the Nord-Cotentin radioecological study

    International Nuclear Information System (INIS)

    Epidemiological studies have shown a trend towards an excess number of leukaemia cases in the region of Nord-Cotentin (France) where, in particular, the La Hague nuclear reprocessing plant is located. In 1997, it was suggested that the risk of leukaemia was associated with some aspects of lifestyle, in particular, the consumption of local seafood and use of local beaches. To respond to public concern, the French Ministries of the Environment and Health decided to commission complementary epidemiological studies and a detailed radioecological analysis. The radioecological study was entrusted to a group of experts with various backgrounds (inspectors, governmental experts, operators, experts from non-governmental laboratories and foreign experts) - the Nord-Cotentin Radioecology Group. Its principal objective was to assess realistically the exposure to ionising radiation of young people from 0 to 24 years of age who had lived near the La Hague nuclear reprocessing plant and to estimate their risk of radiation-induced leukaemia from 1978 through 1996, the period covered by the epidemiological studies. The Group chose to use a three-stage approach: reconstruction of the population of young people from 0 to 24 years who resided in the region between 1978 and 1996, assessment of their exposure to all sources of ionising radiation, and estimation of the risk of radiation-induced leukaemia attributable to this exposure. The collective red bone marrow dose due to the discharges from the local nuclear facilities from Nord-Cotentin has thus been estimated at approximately 0.5 man-Sv, which is less than 0.2% of the total exposure to ionising radiation, including natural and medical sources and fallout from atmospheric testing and the accident at Chernobyl. The number of cases of radiation-induced leukaemia attributable to discharges from the local nuclear facilities based on the estimated level of exposure was around 0.002 over this period. This is the best estimate, in the

  13. Capturing Cultural Glossaries: Case-study I *

    Directory of Open Access Journals (Sweden)

    Matete Madiba

    2011-10-01

    Full Text Available

    Abstract: This article is a presentation of a brief cultural glossary of Northern Sotho cooking terms. The glossary is mainly composed of names for utensils and ingredients, and action words for the processes involved in the preparation of cultural dishes. It also contains names of dishes tied to some idiomatic expressions in a way eliciting cultural experiences that can lead to an under-standing of indigenous knowledge systems. The article seeks to explore ways of capturing cultural glossaries to feed into the national dictionary corpora by using a case-study approach to investigate the processes that led to the generation of this specific school-based project. A number of issues that surfaced in this project, can possibly serve as models for the collection of authentic glossaries that can support dictionary making in African languages.

    Keywords: CULTURAL GLOSSARY, INDIGENOUS KNOWLEDGE SYSTEMS, CULTURAL TERMINOLOGY, CORPUS, AUTHENTIC GLOSSARY, CONTEXTUALISATION, MARGIN-ALIZED LANGUAGES, OUTCOMES-BASED EDUCATION, PERFORMANCE INDICATOR, ASSESSMENT CRITERIA, RANGE STATEMENT, TRADITIONAL DISHES, LANGUAGE VAL-ORISATION, SIMULTANEOUS FEEDBACK, COMMUNICATIVE APPROACH, STRUCTURAL APPROACH, METONYMY

    Opsomming: Die totstandbrenging van kulturele woordversamelings: Ge-vallestudie I. Hierdie artikel is 'n aanbieding van 'n kort kulturele woordversameling van Noord-Sothokookterme. Die woordversameling bestaan hoofsaaklik uit die name van gereedskap en bestanddele, en handelingswoorde vir die prosesse betrokke by die voorbereiding van kulturele geregte. Dit bevat ook name van geregte wat verbind is met sekere idiomatiese uitdrukkings wat op 'n manier kulturele ervarings oproep wat kan lei tot die verstaan van inheemse kennisstelsels. Die artikel probeer om maniere te ondersoek waarop kulturele woordversamelings in die nasionale woordeboekkorpusse ingevoer kan word deur 'n gevallestudiebenadering te volg om die prosesse te ondersoek wat tot die

  14. Case studies: Soil mapping using multiple methods

    Science.gov (United States)

    Petersen, Hauke; Wunderlich, Tina; Hagrey, Said A. Al; Rabbel, Wolfgang; Stümpel, Harald

    2010-05-01

    Soil is a non-renewable resource with fundamental functions like filtering (e.g. water), storing (e.g. carbon), transforming (e.g. nutrients) and buffering (e.g. contamination). Degradation of soils is meanwhile not only to scientists a well known fact, also decision makers in politics have accepted this as a serious problem for several environmental aspects. National and international authorities have already worked out preservation and restoration strategies for soil degradation, though it is still work of active research how to put these strategies into real practice. But common to all strategies the description of soil state and dynamics is required as a base step. This includes collecting information from soils with methods ranging from direct soil sampling to remote applications. In an intermediate scale mobile geophysical methods are applied with the advantage of fast working progress but disadvantage of site specific calibration and interpretation issues. In the framework of the iSOIL project we present here some case studies for soil mapping performed using multiple geophysical methods. We will present examples of combined field measurements with EMI-, GPR-, magnetic and gammaspectrometric techniques carried out with the mobile multi-sensor-system of Kiel University (GER). Depending on soil type and actual environmental conditions, different methods show a different quality of information. With application of diverse methods we want to figure out, which methods or combination of methods will give the most reliable information concerning soil state and properties. To investigate the influence of varying material we performed mapping campaigns on field sites with sandy, loamy and loessy soils. Classification of measured or derived attributes show not only the lateral variability but also gives hints to a variation in the vertical distribution of soil material. For all soils of course soil water content can be a critical factor concerning a succesful

  15. Evolution of Terrorist Network using Clustered approach: A Case study

    DEFF Research Database (Denmark)

    Nizamani, Sarwat; Memon, Nasrullah

    2011-01-01

    In the paper we present a cluster based approach for terrorist network evolution. We have applied hierarchical agglomerative clustering approach to 9/11 case study. We show that, how individual actors who are initially isolated from each other are converted in small clusters and result in a fully...

  16. Intentionality in the Writing Process: A Case Study.

    Science.gov (United States)

    Knoblauch, C. H.

    1980-01-01

    Addresses ways in which discourse can be categorized, focusing on the relationship between writer and audience. Describes results of a case study of the proposal writing of executives in a large consulting firm to illustrate concepts related to intentionality in writing. (FL)

  17. Self-Concept of Pregnant Adolescents: A Case Study.

    Science.gov (United States)

    Elkes, Barbara Halpren; Crocitto, John A.

    1987-01-01

    Used case study approach to assess self-concepts of pregnant adolescents regarding life history, personality traits, and development. Results revealed common themes of historic background and personality traits: no intact families, lack of trust in family members, history of drug and alcohol abuse, permissive sexual attitudes and early sexual…

  18. Prehospital airway management: A prospective case study.

    Science.gov (United States)

    Wilbers, N E R; Hamaekers, A E W; Jansen, J; Wijering, S C; Thomas, O; Wilbers-van Rens, R; van Zundert, A A J

    2011-01-01

    We conducted a one-year prospective study involving a prehospital Emergency Medical Service in the Netherlands to investigate the incidence of failed or difficult prehospital endotracheal intubation. During the study period the paramedics were asked to fill in a registration questionnaire after every endotracheal intubation. Of the 26,271 patient contacts, 256 endotracheal intubations were performed by paramedics in one year. Endotracheal intubation failed in 12 patients (4.8%). In 12.0% of 249 patients, a Cormack and Lehane grade III laryngoscopy was reported and a grade IV laryngoscopy was reported in 10.4%. The average number of endotracheal intubations per paramedic in one year was 4.2 and varied from zero to a maximum of 12. The median time between arrival on the scene and a positive capnograph was 7 min.38 s in the case of a Cormack and Lehane grade I laryngoscopy and 14 min.58 s in the case of a Cormack and Lehane grade 4 laryngoscopy. The incidence of endotracheal intubations performed by Dutch paramedics in one year was low, but endotracheal intubation was successful in 95.2%, which is comparable with findings in international literature. Early capnography should be used consistently in prehospital airway management. PMID:21612142

  19. Case Study of the California Cement Industry

    Energy Technology Data Exchange (ETDEWEB)

    Coito, Fred; Powell, Frank; Worrell, Ernst; Price, Lynn; Friedmann, Rafael

    2005-05-01

    California is the largest cement producing state in theU.S., accounting for between 10 percent and 15 percent of U.S. cementproduction and cement industry employment. The cement industry inCalifornia consists of 31 sites that consume large amounts of energy,annually: 1,600 GWh of electricity, 22 million therms of natural gas, 2.3million tons of coal, 0.25 tons of coke, and smaller amounts of wastematerials, including tires. The case study summarized in this paperfocused on providing background information, an assessment ofenergy-efficiency opportunities and barriers, and program recommendationsthat can be used by program planners to better target products to thecement industry. The primary approach to this case study involvedwalk-through surveys of customer facilities and in depth interviews withcustomer decision makers and subsequent analysis of collected data. Inaddition, a basic review of the cement production process was developed,and summary cement industry energy and economic data were collected, andanalyzed. The analysis of secondary data provides background informationon the cement industry and identification of potential energy-efficiencyopportunities. The interviews provide some understanding of the customerperspective about implementation of energy-efficiencyprojects.

  20. Delayed spinal extradural hematoma following thoracic spine surgery and resulting in paraplegia: a case report

    Directory of Open Access Journals (Sweden)

    Parthiban Chandra JKB

    2008-05-01

    Full Text Available Abstract Introduction Postoperative spinal extradural hematomas are rare. Most of the cases that have been reported occured within 3 days of surgery. Their occurrence in a delayed form, that is, more than 72 hours after surgery, is very rare. This case is being reported to enhance awareness of delayed postoperative spinal extradural hematomas. Case presentation We report a case of acute onset dorsal spinal extradural hematoma from a paraspinal muscular arterial bleed, producing paraplegia 72 hours following surgery for excision of a spinal cord tumor at T8 level. The triggering mechanism was an episode of violent twisting movement by the patient. Fresh blood in the postoperative drain tube provided suspicion of this complication. Emergency evacuation of the clot helped in regaining normal motor and sensory function. The need to avoid straining of the paraspinal muscles in the postoperative period is emphasized. Conclusion Most cases of postoperative spinal extradural hematomas occur as a result of venous bleeding. However, an arterial source of bleeding from paraspinal muscular branches causing extradural hematoma and subsequent neurological deficit is underreported. Undue straining of paraspinal muscles in the postoperative period after major spinal surgery should be avoided for at least a few days.

  1. Scheduling job shop - A case study

    Science.gov (United States)

    Abas, M.; Abbas, A.; Khan, W. A.

    2016-08-01

    The scheduling in job shop is important for efficient utilization of machines in the manufacturing industry. There are number of algorithms available for scheduling of jobs which depend on machines tools, indirect consumables and jobs which are to be processed. In this paper a case study is presented for scheduling of jobs when parts are treated on available machines. Through time and motion study setup time and operation time are measured as total processing time for variety of products having different manufacturing processes. Based on due dates different level of priority are assigned to the jobs and the jobs are scheduled on the basis of priority. In view of the measured processing time, the times for processing of some new jobs are estimated and for efficient utilization of the machines available an algorithm is proposed and validated.

  2. Nightmares and psychotic decompensation: a case study.

    Science.gov (United States)

    Levin, R; Daly, R S

    1998-01-01

    There have been numerous reports in the literature on the descriptive similarities between a severe nightmare and an acute psychotic episode. Nightmares may be a prelude to psychotic decompensation, and it has been suggested that frequent lifelong nightmares may even be diagnostic of an underlying vulnerability to psychosis. In this report, we present a case study of a 40-year old female experiencing chronic paranoid schizophrenia, whose two witnessed psychotic relapses in the hospital were immediately preceded by intense and vivid nightmare attacks. Significantly, the content of these nocturnal dreams was thematically consistent with her waking hallucinations, suggesting a direct continuity between these experiences. We propose that further systematic study of the dreams and nightmares of individuals diagnosed with schizophrenia may be particularly useful in understanding their phenomenological experience.

  3. Percutaneous CT-guided biopsy of the musculoskeletal system: Results of 2027 cases

    Energy Technology Data Exchange (ETDEWEB)

    Rimondi, Eugenio, E-mail: eugenio.rimondi@ior.it [Radiology Department, Istituto Ortopedico Rizzoli, Bologna (Italy); Rossi, Giuseppe [Interventional Angiography Department, Istituto Ortopedico Rizzoli, Bologna (Italy); Bartalena, Tommaso [Radiology Department, University of Bologna (Italy); Ciminari, Rosanna [Radiology Department, Istituto Ortopedico Rizzoli, Bologna (Italy); Alberghini, Marco [Surgical Pathology Department, Istituto Ortopedico Rizzoli, Bologna (Italy); Ruggieri, Pietro; Errani, Costantino; Angelini, Andrea; Calabro, Teresa; Abati, Caterina Novella [Orthopaedic Oncology Department, Istituto Ortopedico Rizzoli, Bologna (Italy); Balladelli, Alba [Laboratory of Experimental Oncology, Istituto Ortopedico Rizzoli, Bologna (Italy); Tranfaglia, Cristina [Nuclear Medicine Department, Maggiore Hospital, Bologna (Italy); Mavrogenis, Andreas F. [Orthopaedic Oncology Department, Istituto Ortopedico Rizzoli, Bologna (Italy); Vanel, Daniel [Bone Tumor Center, Istituto Ortopedico Rizzoli, Bologna (Italy); Mercuri, Mario [Orthopaedic Oncology Department, Istituto Ortopedico Rizzoli, Bologna (Italy)

    2011-01-15

    Introduction: Biopsy of the musculoskeletal system is useful in the management of bone lesions particularly in oncology but they are often challenging procedures with a significant risk of complications. Computed tomography (CT)-guided needle biopsies may decrease these risks but doubts still exist about their diagnostic accuracy. This retrospective analysis of the experience of a single institution with percutaneous CT-guided biopsy of musculoskeletal lesions evaluates the results of these biopsies for bone lesions either in the appendicular skeleton or in the spine, and defines indications. Materials and methods: We reviewed the results of 2027 core needle biopsies performed over the past 18 years at the authors' institution. The results obtained are subject of this paper. Results: In 1567 cases the correct diagnosis was made with the first CT-guided needle biopsy (77.3% accuracy rate), in 408 cases the sample was not diagnostic and in 52 inadequate. Within 30 days these 408 patients underwent another biopsy, which was diagnostic in 340 cases with a final diagnostic accuracy of 94%. Highest accuracy rates were obtained in primary and secondary malignant lesions. Most false negative results were found in cervical lesions and in benign, pseudotumoral, flogistic, and systemic pathologies. There were 22 complications (18 transient paresis, 3 haematomas, 1 retroperitoneal haematoma) which had no influence on the treatment strategy, nor on patient outcome. Conclusion: This technique is reliable and safe and should be considered nowadays the gold standard for biopsies of the musculoskeletal system.

  4. Bilingual education in Slovakia: A Case Study

    Directory of Open Access Journals (Sweden)

    Silvia Pokrivčáková

    2013-06-01

    The paper includes partial results of the research project KEGA 036UKF-4/2013 Creating university textbooks and multimedia courses for a new study program funded by the Ministry of Education of the Slovak Republic.

  5. STAKEHOLDERS AND APART HOTELS: MULTIPLE CASE STUDY

    Directory of Open Access Journals (Sweden)

    Patrícia Freire Ferreira Oliveira

    2012-09-01

    Full Text Available Means of accommodation involve a wide range of social actors and agents, as well as different business models. Management strategies in this sector have been increasingly important for long-term sustainability and competitiveness of business organizations. This study aims to analyze the interactions between apart-hotels and their stakeholders to foster an improvement of services provided, aligning the interface of strategic management from the point of view of managers and their key stakeholders. It is an exploratory study, with qualitative chacter, along with multiple case studies of the following establishments: Travel Inn, Hotels Slaviero and Etoile george v. Brazilian enterprises, which manage lodging facilities with apart-hotel concepts, combining features that enable comparative analysis of the study. For conceptual understanding, this study was based on literature about stakeholders, taking the work of Freeman (1984 and Freeman et al (2010 as main references. The research was conducted through semi-structured interviews with managers of lodging facilities and their key stakeholders and through direct observation and documentation. We found that not all groups of influence are considered in the planning of service flats. However, the organizations surveyed indicated that the market has realized the importance of the groups that exert influence and are influenced by their goals, and are therefore increasingly alert for integration of such groups in their strategic planning.

  6. Percutaneous Nephrolithotomy: Our Results of a Single-Centre Analysis in 2300 Cases

    Directory of Open Access Journals (Sweden)

    Akif Erbin

    2014-03-01

    Full Text Available Aim: In this study, we evaluated the results of 2300 patients who underwent percutaneous nephrolithotomy (PNL between March 2002 and April 2013. Methods: In our clinic, a total of 2300 PNL operations were performed between March 2002 - April 2013. Demographic characteristics (age, gender, body mass index, stone features (side, size, location, clinical characteristics of the urinary tract (renal anomaly, previous surgery, previous extracorporeal shock wave lithotripsy, operation parameters (duration of the intervention and fluoroscopy, number of access, location of access, transfusion, complications, post-operative data (length of hospital stay, transfusion, complications, stone-free were recorded on PNL forms. The data were analyzed retrospectively. Results: Of all the PNL operations, 1225 (53.2% were left-sided, 1074 (46.6% were right-sided and 1 was bilateral. The mean age of the subjects was 43.5 (7-83 years and the mean body mass index was 26.6 kg/m2 (12-51. A total of 46 (2% cases had renal anomalies. There were 16 patients with horseshoe kidney. More than one accesses was performed in 18.6% of the patient and intercostal access was done in 9.8%. Perioperative and post-operative transfusion rates were 1.4% and 2.9%, respectively. The mean stone size was 7.5±4.1 cm2. Stone-free (SF rate was 65.1% and success rate was 78.5%. Conclusion: With increasing experience and advances in endourology, PNL is being widely performed with low morbidity and high success in our country as in the world. (The Me­di­cal Bul­le­tin of Ha­se­ki 2013; 51: 19-24

  7. Clinical Results and Complications of Lower Limb Lengthening for Fibular Hemimelia: A Report of Eight Cases.

    Science.gov (United States)

    Mishima, Kenichi; Kitoh, Hiroshi; Iwata, Koji; Matsushita, Masaki; Nishida, Yoshihiro; Hattori, Tadashi; Ishiguro, Naoki

    2016-05-01

    Fibular hemimelia is a rare but the most common congenital long bone deficiency, encompassing a broad range of anomalies from isolated fibular hypoplasia up to substantial femoral and tibial shortening with ankle deformity and foot deficiency. Most cases of fibular hemimelia manifest clinically significant leg length discrepancy (LLD) with time that requires adequate correction by bone lengthening for stable walking. Bone lengthening procedures, especially those for pathological bones, are sometimes associated with severe complications, such as delayed consolidation, fractures, and deformities of the lengthened bones, leading to prolonged healing time and residual LLD at skeletal maturity. The purpose of this study was to review our clinical results of lower limb lengthening for fibular hemimelia.This study included 8 Japanese patients who diagnosed with fibular hemimelia from physical and radiological findings characteristic of fibular hemimelia and underwent single or staged femoral and/or tibial lengthening during growth or after skeletal maturity. LLD, state of the lengthened callus, and bone alignment were evaluated with full-length radiographs of the lower limb. Previous interventions, associated congenital anomalies, regenerate fractures were recorded with reference to medical charts and confirmed on appropriate radiographs. Successful lengthening was defined as the healing index <50 days/cm without regenerate fractures.A significant difference was observed in age at surgery between successful and unsuccessful lengthening. The incidence of regenerate fractures was significantly correlated with callus maturity before frame removal. LLD was corrected within 11 mm, whereas mechanical axis deviated laterally.Particular attention should be paid to the status of callus maturation and the mechanical axis deviation during the treatment period in fibular hemimelia. PMID:27227952

  8. French brain tumor data bank: methodology and first results on 10,000 cases.

    Science.gov (United States)

    Bauchet, Luc; Rigau, Valérie; Mathieu-Daudé, Hélène; Figarella-Branger, Dominique; Hugues, Delphine; Palusseau, Loreleï; Bauchet, Fabienne; Fabbro, Michel; Campello, Chantal; Capelle, Laurent; Durand, Anne; Trétarre, Brigitte; Frappaz, Didier; Henin, Dominique; Menei, Philippe; Honnorat, Jérome; Segnarbieux, François

    2007-09-01

    This work aims to prospectively record all primary central nervous system tumors (PCNST), in France, for which histological diagnosis is available. The objectives are to create a national registry and a network to perform epidemiological studies, to implement clinical and basic research protocols, and to harmonize the healthcare of patients affected by PCNST. Following a feasibility study, including an estimate of the gross incidence of PCNST (15.8/100,000 person-years) in France, all French neuropathology and neurosurgery departments decided to participate in the program. For each patient, the neurosurgeon and the neuropathologist complete a data file containing socio-demographic, clinical, radiologic and anatomopathologic information. The Tumor Registry from Herault is authorized to compile the data files with personal identifiers. In 2.5 years, 10,093 cases of newly diagnosed PCNST have been recorded. Tumor resections were performed in 75.3%, while biopsies accounted for 24.7%. Histological diagnoses included glioma (49.6%), other neuroepithelial tumors (3.8%), meningioma (30.9%), neurinoma (8.7%), lymphoma (2.9%) and others (4.1%). Cryopreservation was reported for 2,261 PCNST specimens. Clinical and radiological aspects were also recorded. Preliminary results are encouraging and stimulating for the long-term goal of creating a National Registry and a National Network for patients affected by PCNST. To our knowledge, this is the first European databank dedicated to PCNST, with collection of clinical, radiological and histological data (including cryopreservation of the specimen). The creation of this registry and this database may have major clinical and fundamental implications. PMID:17431547

  9. Interstitial Pregnancy Resulting in a Viable Infant Coexistent with Massive Perivillous Fibrin Deposition: A Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Yusuke Tanaka

    2014-05-01

    Full Text Available Objective - The objective of this report is to describe a rare case of interstitial pregnancy ultimately resulting in a viable infant coexistent with massive perivillous fibrin deposition (MPFD. Study Design - This study is a case report and literature review. Results - A 35-year-old female patient underwent cesarean section at 32 weeks of gestation due to fetal growth restriction (FGR and breech presentation. During the operation, a diagnosis of interstitial pregnancy was established. There was no evidence of placental separation. We decided to complete surgery without removal of the placenta and waited until the placenta delivered spontaneously. The conservative management was successful, and the patient was discharged on postoperative day 13. The pathologic examination showed MPFD. Conclusion - If interstitial pregnancies are not diagnosed at an early gestational age, it can result in a viable fetus, but such pregnancies may be associated with FGR or placenta accreta.

  10. Uterine arterial embolization for the treatment of adenomyosis: an analysis of therapeutic results in 80 cases

    International Nuclear Information System (INIS)

    Objective: To discuss the therapeutic effect of uterine arterial embolization in treating adenomyosis. Methods: Uterine arterial embolization was performed in 80 patients with adenomyosis. The patients were followed up for 3, 6, 12 and 24 months after the operation. After the treatment the degree of dysmenorrhea, the menstrual flow and the uterine volume were observed and were compared with those before the treatment. Results: After uterine arterial embolization the clinical symptoms were relieved in all 80 patients. The menstrual flow was markedly decreased, the anemia was obviously improved and the uterine volume was significantly reduced, while the ovary functioning was not apparently affected. The symptom of dysmenorrhea completely disappeared one month after the therapy in 76 cases and four months after the therapy in the remaining 4 cases. Conclusion: Uterine arterial embolization is a mini-invasive and safe therapy with remarkable therapeutic results and few side-effects. Therefore, this treatment can significantly improve the patient's living quality. (authors)

  11. Study on Case-Based Fixture Design

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Fixture is an important manufacturing activity. A fixture design system based on case-based reasoning (CBR) is proposed in this paper. A new method of case representation on the basis of fixture function is presented, where the case representation is constituted of workpiece knowledge, processing feature knowledge, and fixture feature knowledge. Running the prototype system shows that the knowledge representation method, using cases, is a better way to transform and explain the design knowledge.

  12. Obsessional Slowness in College Students: Case Studies

    Science.gov (United States)

    Johnson, Aleta

    2014-01-01

    Cases of obsessional slowness, a variant of obsessive compulsive disorder, have been documented in case literature regarding relatively low functioning populations. However, obsessional slowness can also present in higher functioning populations, including college and graduate students, as illustrated here by three case examples from a competitive…

  13. Long-term results of complex left ventricular reconstruction surgery: case report.

    Science.gov (United States)

    Letsou, George V; Forrester, Matthew; Frazier, O H

    2011-01-01

    Left ventricular reconstruction is advocated as a surgical option for patients with severe congestive heart failure. Despite initial enthusiasm for this procedure, reports of long-term results are sparse. Herein, we describe a particularly gratifying case of left ventricular reconstruction in a 43-year-old man, who continues to have excellent left ventricular function 10 years postoperatively. This approach may be a reasonable alternative to cardiac transplantation in patients who lack other treatment options.

  14. Compressive brainstem deformation resulting from subdural hygroma after neurosurgery: a case report

    Institute of Scientific and Technical Information of China (English)

    YU Shu-qing; WANG Ji-sheng; JI Nan

    2008-01-01

    @@ Acute and chronic subdural hygromas are common postoperative clinical complications of ventricular shunting, arachnoid cyst marsupialization and arachnoid cyst resection.1 This article introduces a case of subdural hygroma after resection of a space-occupying lesion in the left lateral ventricle that resulted in compressive brainstem deformation and reviewed the recent related literature. The conclusion is that in related surgical procedures, prevention of rapid cerebrospinal fluid loss and excessive fluctuations in intracranial pressure are especially important.

  15. The virtual information: a case study

    Directory of Open Access Journals (Sweden)

    Ginevra Gravili

    2012-09-01

    Full Text Available In todays economics, the fact that information is a major factor of production and of increasing importance as a source of competitive advantage is a generally accepted truism. The trend towards global markets has strongly impacted the competitive situation of many enterprises. Never has the economic environment been subject to so many drastic and rapid changes. This put new weight factors on the requirements for design of business process. This paper explores the case of an Italian legal office that has studied more and more innovative solutions both to satisfy the demands of the clienteles and to oppose the action of the new competitors. Comparing classic models and the theories of Porter with the characteristics and needs of new economy, it shows as the ability to possess, to easily have access, to creatively use of information constitutes one of the more strategic sources of the competitive advantage.

  16. Telepractice for pediatric Dysphagia: a case study.

    Science.gov (United States)

    Malandraki, Georgia A; Roth, Melissa; Sheppard, Justine Joan

    2014-01-01

    A closed-ended intensive pediatric swallowing telepractice program was developed and piloted in one pediatric patient with Opitz BBB/G and Asperger's Syndromes, oropharyngeal dysphagia and aerophagia. The present study is a case report. Outcome variables included behavioral, swallowing and quality of life variables, and were assessed at baseline and at the end of the four-week program. Selective variables were also assessed at a follow-up family interview four weeks post program completion. Over the four-week intervention period, the patient demonstrated substantial improvements in: oral acceptance of eating-related objects and a variety of foods (behavioral variable), timing of voluntary saliva swallows and aerophagia levels (swallowing variables) and quality of life. Follow-up interview analysis showed that most skills were retained or improved one-month post intervention. This intensive telepractice program proved to be feasible and effective for this pediatric patient with dysphagia. PMID:25945217

  17. Telepractice for Pediatric Dysphagia: A Case Study

    Directory of Open Access Journals (Sweden)

    Georgia A. Malandraki

    2014-09-01

    Full Text Available A closed-ended intensive pediatric swallowing telepractice program was developed and piloted in one pediatric patient with Opitz BBB/G and Asperger’s Syndromes, oropharyngeal dysphagia and aerophagia. The present study is a case report. Outcome variables included behavioral, swallowing and quality of life variables, and were assessed at baseline and at the end of the four-week program. Selective variables were also assessed at a follow-up family interview four weeks post program completion. Over the four-week intervention period, the patient demonstrated substantial improvements in: oral acceptance of eating-related objects and a variety of foods (behavioral variable, timing of voluntary saliva swallows and aerophagia levels (swallowing variables and quality of life. Follow-up interview analysis showed that most skills were retained or improved one-month post intervention. This intensive telepractice program proved to be feasible and effective for this pediatric patient with dysphagia.

  18. Understanding Support - lessons from a case study

    Directory of Open Access Journals (Sweden)

    Chris Sauer

    1993-11-01

    Full Text Available Support from top management and others is agreed to be an important factor in information systems success and failure, but little is written about how it has its effect and how it might be managed to a project's advantage. A recently developed conceptual framework is described. It covers the nature and forms of support, the way support affects project outcomes, the bases on which support is provided, and the strategies by which support may be managed. The framework is used to analyse a case study in several stages. At the end of the analysis of each stage, the framework's utility is assessed in terms of its explanatory value and the practical advice it suggests. Areas for further research are identified.

  19. Case studies in outcome-based education.

    Science.gov (United States)

    Davis, Margery H; Amin, Zubair; Grande, Joseph P; O'Neill, Angela E; Pawlina, Wojciech; Viggiano, Thomas R; Zuberi, Rukhsana

    2007-09-01

    Outcome-based education is one of the most significant global developments in medical education in recent years. This paper presents four case studies of outcome-based education from medical schools in different parts of the world; Scotland; USA; Pakistan; and Singapore. The outcome-based curricula have either been in place for some time, are evolving or are at the planning proposal stage. The outcomes, change process and implementation of the outcome-based approach are described. Variation in the extent to which each medical school has implemented outcome-based education is discussed and key points for successful implementation are highlighted. This paper is based on the pre-conference symposium "outcome-based curricula: global perspectives" presented by the authors at the 4th Asia Pacific Medical Education Conference (APMEC) in Singapore, 8-11 February, 2007. PMID:18236260

  20. Robust control systems theory and case studies

    CERN Document Server

    Mackenroth, Uwe

    2004-01-01

    "Robust Control Systems" gives a self-contained introduction to modern Control Theory. It thus adds a textbook to the existing research-oriented literature on Robust Control. The author lays emphasis on the modern aspects of the design of controllers with prescribed performance and robustness properties. Different to the classical engineering approach, a rigorous mathematical treatment is essential for the full understanding and applicability of the modern methods such as H2 or H8 control or methods based on the structured singular value µ. Nevertheless, no prior knowledge of Control Theory is required as the classical fundamentals are introduced within the first few chapters. Subsequently a large part of the text provides elementary examples and industrial case studies, which are developed in full detail to show how modern methods can be applied to advanced problems. They make intensive use of MATLAB, especially the Control Systems Toolbox and the µ-Analysis and Synthesis Toolbox.