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Sample records for case study involving

  1. Experimental quantum annealing: case study involving the graph isomorphism problem

    Science.gov (United States)

    Zick, Kenneth M.; Shehab, Omar; French, Matthew

    2015-06-01

    Quantum annealing is a proposed combinatorial optimization technique meant to exploit quantum mechanical effects such as tunneling and entanglement. Real-world quantum annealing-based solvers require a combination of annealing and classical pre- and post-processing; at this early stage, little is known about how to partition and optimize the processing. This article presents an experimental case study of quantum annealing and some of the factors involved in real-world solvers, using a 504-qubit D-Wave Two machine and the graph isomorphism problem. To illustrate the role of classical pre-processing, a compact Hamiltonian is presented that enables a reduced Ising model for each problem instance. On random N-vertex graphs, the median number of variables is reduced from N2 to fewer than N log2 N and solvable graph sizes increase from N = 5 to N = 13. Additionally, error correction via classical post-processing majority voting is evaluated. While the solution times are not competitive with classical approaches to graph isomorphism, the enhanced solver ultimately classified correctly every problem that was mapped to the processor and demonstrated clear advantages over the baseline approach. The results shed some light on the nature of real-world quantum annealing and the associated hybrid classical-quantum solvers.

  2. Three case studies involving Leptospira interrogans serovar pomona infection in mixed farming units : case report

    Directory of Open Access Journals (Sweden)

    B. Gummow

    1999-07-01

    Full Text Available Three case studies involving Leptospira interrogans serovar pomona outbreaks within mixed farming systems in South Africa are described. On 2 farms, pigs constituted the main enterprise with cattle and sheep of secondary importance. On each of these 2 farms, abortion due to L. pomona in sows was confirmed by culture, and antibody titres to pomona were detected in cattle, sheep, horses and dogs. On the 3rd farm, a piggery was ofsecondary importance to cattle farming. Abortion and death in cows occurred on this farmand serology showed titres to various serovars, including pomona. L. pomona was also isolated from bovine urine, an aborted bovine foetus and kidneys from slaughtered pigs. This particular case study was regarded as clinically atypical in that adult Jersey cattle died of acute leptospirosis in a semiarid region of South Africa. In all 3 case studies, the poor management of pig effluent and of the drinking water and its sources played a pivotal role in the transmission of the disease. Inadequate vaccination of animals against Leptospira and poor record-keeping within the secondary farming enterprises were also contributing factors to the spread of leptospirosis.

  3. Corporate branding in social media - Stakeholder involvement in value co-creation: A case study

    OpenAIRE

    Pietarinen, Stella

    2014-01-01

    Objective of the Study: The objective of the thesis was to explore how the case organization (Wärtsilä Corporation) strategically builds and manages its corporate brand in social media, with the focus on value co-creation of brand through stakeholder involvement in brand building in social media. The research questions consider three aspects: 1) the case organization's overall corporate branding strategy in social media towards different stakeholder groups; 2) the involvement of the case ...

  4. Organizational values in general practice and public involvement: case studies in an urban district.

    Science.gov (United States)

    Brown, I

    2001-05-01

    A multiple case study design was used to explore dimensions of organizational values in general practice with respect to developing public involvement. The study was undertaken in an urban district in England with data collected through in-depth individual and focus group interviews with service providers and service users. Four general practice organizations were randomly selected for study after sorting all in the district according to their record of developing involvement activities. The case studies provide evidence of how organizational values can differ markedly in general practice in relation to ideas of public involvement, with consequences for the quantity and quality of activities for involving local people and service users. The differences manifest themselves in the beliefs and attitudes of service providers about the purpose of the organization and the types of relationships that are appropriate with service users and local people. Service users appear to be very perceptive to the underlying ethos and purpose to their practice organization and this affects their responsiveness to initiatives for their involvement. The dimensions of the different values found in the study appear to be essentially the same as a number of established empirical findings of variations in values in general practice: an orientation to a narrow medical role and to general practice as a business are associated with a low valuation of involvement; an orientation to teamwork and to a broader social role appear more congruent with the development of involvement. Power is a critical issue in this setting with evidence in the study of the dominance of the medical practitioners in establishing organizational values and the nature of public involvement activities. PMID:11560732

  5. DEMOGRAPHIC DISTRIBUTION, CLINICAL PRESENTATIONS AND SITES OF INVOLVEMENT IN INTESTINAL TUBERCULOSIS: A STUDY OF 50 CASES

    Directory of Open Access Journals (Sweden)

    Mitesh kumar R

    2015-01-01

    Full Text Available OBJECTIVES: This study was conducted to know the distribution of intestinal tuberculosis in various age groups and sex, and to study common presenting symptoms and frequency of involvement of different sites in intestinal tuberculosis. METHODS: The study reports 50 cases of intestinal tuberculosis admitted at tertiary care hospital, during 2007 to 2009, who required surgery . RESULTS: More than 50% patients were between 11 to 30 years of age. Males and females equally affected by the condition . Fever, anorexia, vomiting and weight loss are common symptoms along with abdominal pain being present in all patients. Ileum was most commonly affected part of the intestine, while rectum was never seen to be involved in any cases in the study. CONCLUSION: As the condition affects children and adolescent more frequently, prevention, early diagnosis and proper medical treatment in this age group are very important factors to reduce the disease burden to society. As ileum was most commonly affected part, its surgical removal may lead to problems relating with malnutrition and needs long term follow up and further studies to know the long term consequences of surgery for the condition.

  6. Governing integration through sports. A case study of civil society involvement in welfare policy

    DEFF Research Database (Denmark)

    Agergaard, Sine; Michelsen la Cour, Annette

    2012-01-01

    governing techniques of the welfare state. To do so, a case study approach is applied. First of all, the article will describe the ways in which the issues of enhancing ethnic integration through sports is represented (thought of as a problem) by the involved public authorities and non-state actors using......To an increasing extent, civil sports associations are becoming entangled in welfare policies of the Danish state. This article problematises the ways in which non-state actors are involved in the conduct of integration policy in order to discuss the ways in which sports associations take over......-state actors come to use New Public Management. Key-words: governmentality, problematisation, assemblage, performance measurement...

  7. The contribution of advisory committees and public involvement to large studies: case study

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    Tew Jerry

    2010-12-01

    Full Text Available Abstract Background Many large studies have complex advisory committee structures, yet there is no empirical evidence regarding their optimal composition, scope and contribution. The aim of this study was to inform the committee and advice infrastructure for future research studies. Methods In the context of a five-year study funded by the UK National Institute for Health Research, three advisory committees were formed. In addition, advice was obtained from individual experts. All recommendations received in the start-up phase (first seven months of the study were recorded, along with the decision about implementation of the recommendation. A particular focus was on the impact of public involvement. Results A total of 172 recommendations were made, including 70 from 20 individual experts. The recommendations were grouped into five emergent themes: Scientific, Pragmatic, Resources, Committee and Collaboration. Most recommendations related to strengthening existing components or adding new components to the study protocol. Very few recommendations either proposed removing study components or contradicted other recommendations. Three 'implementation criteria' were identified: scientific value, pragmatic feasibility, and paradigmatic consistency. 103 (60% of recommendations were implemented and 25 (15% were not implemented. The benefits identified by the research team were improved quality and confidence, and the costs were increased cognitive demands, protocol revision time, and slower progress. Conclusions The findings are discussed in the context of the wider literature on public involvement in research. Six recommendations are identified. First, have a clear rationale for each advisory committee expressed as terms of reference, and consider the best balance between committees and individual consultation with experts. Second, an early concern of committees is inter-committee communication, so consider cross-representation and copying minutes

  8. Do Youth Learn Life Skills through Their Involvement in High School Sport? A Case Study

    Science.gov (United States)

    Holt, Nicholas L.; Tink, Lisa N.; Mandigo, James L.; Fox, Kenneth R.

    2008-01-01

    In this study we examined whether and how youth learned life skills through their involvement on a high school soccer team. We collected data from fieldwork and interviews with 12 male student-athletes and the head coach from one team. Results showed that the coach's philosophy involved building relationships and involving student-athletes in…

  9. "You Have the Right to Remain Silent." Two Case Studies in Forensic Linguistics Involving Spanish Speaking Suspects.

    Science.gov (United States)

    Perissinotto, Giorgio

    Two case studies involving possible violations of the rights of Spanish speaking criminal suspects are presented. In cases where suspects do not understand English, the Miranda warnings regarding the right to remain silent must be delivered in their native language and in a way that is understandable to the suspects. In the two cases involving…

  10. EMPLOYEE INVOLVEMENT IN A CHANGE PROCESS - A CASE STUDY FOR ROMANIAN ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Prediscan Mariana

    2015-07-01

    Full Text Available Innovation, competitive advantage, change are some concepts that should be on every organization's agenda, due to the fact the global market leads to global competition so in order to increase the market share, turnover or profit organizations have to incorporate those concepts in their strategies. The outside environment is very unstable and things are evolving very fast so managers from all levels have to acknowledge the importance of change and to identify as soon as possible several new ideas that should be the subject of different change processes. Openness to organizational change has become a mandatory feature for those organizations that want to survive and adapt to the external pressure, helping them to be efficient. Even if in many cases managers are the initiators of change, this process is very complex and needs support and involvement from all the members of the organization, so the employee's attitude and commitment to change is crucial. In many cases employees have a negative attitude towards change and manifest a strong resistance, due to the fact that they are not consulted and are not involved in the process of the identification for the need of change. Without understanding and knowing very well what it is expected from them, employees are afraid of the unknown and prefer to perform their tasks as they did before. Creating a climate and a culture for change is very important, because like this change will be something normal, continuous and people will feel comfortable with any change initiatives, without being surprised, confused or scared. Even if any change process should improve the current state of the organization, sometimes change efforts fail because the ones that resist change are stronger than the ones supporting change. The purpose of this paper is to analyze how often are Romanian employees involved in the processes of change and how important is the role they play. We have also tried to see the Romanian manager

  11. EGPSI case studies: implications of stakeholder involvement for radiological protection policy

    International Nuclear Information System (INIS)

    The key message from the first Villigen Workshop in 1998, which focused on the particularly difficult question of contaminated areas and their restoration to a point where people could continue to live there, was that radiation protection must adapt to meet the needs of society and not the reverse. What sort of change might be required and what could be regarded as feasible was the objective of the second Workshop in 2001. This sought to make some preliminary suggestions by considering a range of initiatives in a number of countries, which exemplified a desire to change the way that radiation protection policy was developed and implemented. Among the conclusions drawn were the need to foster mutual trust between the radiation protection community and society as a whole; to develop approaches to interacting with stakeholders that are sensitive to specific contexts but which share features of openness, inclusiveness and agreed procedures; to clarify the respective roles of the various actors involved; and to understand interactions with stakeholders as opportunities for mutual learning. The task for the third Workshop was thus to move from the still conceptual level of these conclusions towards some more practical guidance for stakeholder involvement in radiation protection decision making. Drawing on the analyses of the three case studies conducted for this Workshop, this presentation addresses the 'when, what, who and how' questions that radiation protection specialists, in common with their counterparts in other technological domains, ask when confronted with the need to organize a stakeholder participation process. A key message is that while there is no one-size-fits-all blueprint for such processes -- given the sheer range and diversity of the situations where they may be appropriate - it is nevertheless possible to identify common themes and features. These should be of assistance to professionals in developing participation processes, and not detract from the

  12. Involvement of external stakeholders in local Health policymaking process: a case study from Odense Municipality, Denmark

    DEFF Research Database (Denmark)

    Eklund Karlsson, Leena; Jakobsen, Mette Winge; Winblad Heiberg, Malin;

    2016-01-01

    Collaboration between research and policy is an essential element for knowledge-based public health. However, only half of the Danish municipalities have experience with collaborating with researchers or other stakeholders. Through content analysis of interviews and policy documents the study...... explores the involvement of external stakeholders in local health policymaking and public officials’ perceptions on involving them. Main involvement was through a personal contact or through a regular hearing. The purpose of involvement was mostly tactical or to solve problems. Politicians had substantial...... influence on the involvement of external stakeholders, allowing only a few to contribute in a closed policymaking process....

  13. Anyang:A Case Study of Foreign University Involvement in Chinese Sustainable New Town Planning

    Institute of Scientific and Technical Information of China (English)

    Menelaos Triantafillou; David J.Edelman

    2012-01-01

    Over the last ten to fifteen years,planning and design professionals in the United States and Europe have increasingly been engaged in consulting work in China.Major Architectural & Engineering firms from the United Kingdom and the United States,for example,have been opening offices in Beijing and Shanghai.Recently,the concern with sustainable urban development and China’s policies to alleviate pressures of urbanization has been an engine for commissions for new town plans and city expansion plans across China’s provinces.During the 2007-2009 academic years,the School of Planning at the University of Cincinnati prepared a conceptual plan for the expansion of the City of Anyang through a collaborative agreement between the city and it.The experience of the faculty leading this project with field work,the planning process,plan preparation,and the engagement of students has revealed some important issues that need to be addressed by planning schools and planning professionals engaged in planning in provincial China.Thus,this paper is a case study of foreign university involvement in Chinese sustainable new town planning,and the following sections discuss the Anyang Eastern New Town Conceptual Plan,identify the key issues regarding preparing the plan,contracting and payment,data availability,data sharing and field investigation,and finally discuss the lessons learned regarding the planning process,project program and expectations.

  14. Limitations of Data on Cell Phone Involvement in Collisions: A Case Study of California

    OpenAIRE

    Griswold, Julia B. Corresponding author; Grembek, Offer

    2014-01-01

    With the increasing prevalence of mobile technology and high-profile crashes bringing attention to distracted driving, data on cell phone involvement in collisions is critical for understanding the extent of the problem, examining the effectiveness of policies, and developing interventions to improve safety. Some limitations of existing data have been previously identified, but this paper examines the specific case of California’s collision data. Temporal, geographic, and jurisdictional tre...

  15. Managing Supplier Involvement in New Product Development: A Multiple-Case Study

    NARCIS (Netherlands)

    F.E.A. van Echtelt (Ferrie); J.Y.F. Wynstra (Finn); A.J. van Weele (Arjan); G.M. Duysters (Geert)

    2006-01-01

    textabstractExisting studies of supplier involvement in new product development have mainly focused on project-related short-term processes and success-factors. This study validates and extends an existing exploratory framework, which comprises both long-term strategic processes and short-term opera

  16. The Management of Parental Involvement in Multicultural Schools in South Africa: A Case Study

    Directory of Open Access Journals (Sweden)

    Sathiapama Michael

    2012-01-01

    Full Text Available The aim of this study was to investigate the management of parental involvement in three multicultural schools in the Umlazi District in Durban, South Africa. A literature survey resulting in a theoretical framework on parental involvement in schools, multicultural schools, and the managing of parental involvement in schools has been done. The contextual background of schools in contemporary South Africa is depicted. A qualitative research design has been used. Focus group discussions have been conducted, with a total of thirty-three principals, teachers and parents. It has found that there is a low level of meaningful contact between school and parents. Apathy exists on the side of parents, low expectations on the side of principals and teachers, and an organisational structure facilitating parent-school interaction is lacking. In managing parental involvement in multicultural schools, school managers display a lack of intercultural sensitivity.

  17. Astronomy and religion (1780-1915). Four case studies involving ideas of extraterrestrial life

    Science.gov (United States)

    Crowe, Michael J.

    The present essay discusses four examples of interactions, two from the eighteenth century and two from the nineteenth. All four cases concern the relations between religion and the astronomical claim that intelligent beings exist elsewhere in space. In each of these four cases religious claims influenced astronomy. Cases 3 and 4 share a feature not usually encountered in studies on the interactions of astronomy and religion in that they are instances where not just theistic belief but in fact core doctrines of a specific religion, Christianity, influenced astronomy. I begin by surveying the interactions between religion and the idea of extraterrestrial intelligent life in the early modern period.

  18. Paediatric radiological practice: A case study involving radiographic imaging of the spinal cord

    International Nuclear Information System (INIS)

    A case study is presented to investigate the risk and benefits of common radiological techniques. The discrepancy between EC quality criteria for paediatric radiology and common practice is pointed out. The achievable dose reduction is to help develop a new working concept. The induced radiation hazard is calculated and compared to the expected benefits. (orig.)

  19. International public health research involving interpreters: a case study from Bangladesh

    Directory of Open Access Journals (Sweden)

    van Teijlingen Edwin

    2005-06-01

    Full Text Available Abstract Background Cross-cultural and international research are important components of public health research, but the challenges of language barriers and working with interpreters are often overlooked, particularly in the case of qualitative research. Methods A case-study approach was used to explore experiences of working with an interpreter in Bangladesh as part of a research project investigating women's experiences of emergency obstetric care. The case study Data from the researcher's field notes provided evidence of experiences in working with an interpreter and show how the model of interviewing was adapted over time to give a more active role to the interpreter. The advantages of a more active role were increased rapport and "flow" in interviews. The disadvantages included reduced control from the researcher's perspective. Some tensions between the researcher and interpreter remained hard to overcome, irrespective of the model used. Independent transcription and translation of the interviews also raised questions around accuracy in translation. Conclusion The issues examined in this case study have broader implications for public health research. Further work is needed in three areas: 1 developing effective relationships with interpreters; 2 the impact of the interpreter on the research process; and 3 the accuracy of the translation and level of analysis needed in any specific public health research. Finally, this paper highlights the importance to authors of reflecting on the potential impact of translation and interpretation on the research process when disseminating their research.

  20. Student Involvement as a Vehicle for Empowerment: A Case Study of the Student Platform for Engineering Education Development

    Science.gov (United States)

    Delaine, David A.; Seif-Naraghi, Sonya B.; Al-Haque, Shahed; Wojewoda, Nicolo; Meninato, Yvonne; DeBoer, Jennifer

    2010-01-01

    This paper examines the mission, structure and outputs of one organisation, the Student Platform for Engineering Education Development (SPEED), as a case study for how student-led organisations can use student involvement to promote and sustain student self-efficacy in an academic field. SPEED attracts young people to engineering through student…

  1. Public/stakeholder involvement at two Department of Energy sites: Case studies

    International Nuclear Information System (INIS)

    Efforts to communicate the results of environmental studies and involve the public in environmental decisions have increased nationwide. Outreach efforts at two US Department of Energy sites (i.e., the Hanford Site in southeastern Washington State and the Pantex Plant in the Texas Panhandle) have used a broad spectrum of communications media, including technical articles (open literature and symposium publications, annual and topical reports); information brochures and fact sheets; video productions; interactive exhibits, presentations at scientific, technical, civic, and other public meetings; and proactive interactions with the news media and with local, state, federal, and other agencies. In addition, representatives of local communities now operate offsite environmental monitoring stations and Native Americans are involved in studying cultural resources, fisheries, and other issues at Hanford and a program to obtain environmental samples from neighbor's property is underway at the Pantex Plant. All major environmental programs, such as the multi-year effort to reconstruct past radiological doses to offsite human populations at Hanford, are now conducted with open public participation

  2. Retrospective study of sonographic findings in bone involvement associated with rotator cuff calcific tendinopathy: preliminary results of a case series

    Directory of Open Access Journals (Sweden)

    Marcello H. Nogueira-Barbosa

    2015-12-01

    Full Text Available Abstract Objective: The present study was aimed at investigating bone involvement secondary to rotator cuff calcific tendonitis at ultrasonography. Materials and Methods: Retrospective study of a case series. The authors reviewed shoulder ultrasonography reports of 141 patients diagnosed with rotator cuff calcific tendonitis, collected from the computer-based data records of their institution over a four-year period. Imaging findings were retrospectively and consensually analyzed by two experienced musculoskeletal radiologists looking for bone involvement associated with calcific tendonitis. Only the cases confirmed by computed tomography were considered for descriptive analysis. Results: Sonographic findings of calcific tendinopathy with bone involvement were observed in 7/141 (~ 5% patients (mean age, 50.9 years; age range, 42-58 years; 42% female. Cortical bone erosion adjacent to tendon calcification was the most common finding, observed in 7/7 cases. Signs of intraosseous migration were found in 3/7 cases, and subcortical cysts in 2/7 cases. The findings were confirmed by computed tomography. Calcifications associated with bone abnormalities showed no acoustic shadowing at ultrasonography, favoring the hypothesis of resorption phase of the disease. Conclusion: Preliminary results of the present study suggest that ultrasonography can identify bone abnormalities secondary to rotator cuff calcific tendinopathy, particularly the presence of cortical bone erosion.

  3. Student involvement as a vehicle for empowerment: a case study of the student platform for engineering education development

    Science.gov (United States)

    Delaine, David A.; Seif-Naraghi, Sonya B.; Al-Haque, Shahed; Wojewoda, Nicolò; Meninato, Yvonne; DeBoer, Jennifer

    2010-08-01

    This paper examines the mission, structure and outputs of one organisation, the Student Platform for Engineering Education Development (SPEED), as a case study for how student-led organisations can use student involvement to promote and sustain student self-efficacy in an academic field. SPEED attracts young people to engineering through student participation in engineering education (EE). SPEED is a global, non-profit student organisation that functions as an interdisciplinary network to diversify dialogue, stimulate change and impact the development of EE and its effect on society. SPEED is directly attracting young people to engineering in various ways: the organisation of its keynote event, the Global Student Forum; facilitating interactions between globally minded, socially inclined engineers with aspirations to change the world; and through the global dissemination of SPEED's work and practices through broad and relevant channels. Short-term outcomes are highlighted here. This case study can serve as a model for student engagement and involvement in other disciplines.

  4. Local community involvement in cultural heritage management: a case study of Melaka Heritage Trail, Malaysia

    OpenAIRE

    ismail, mohd hafizal

    2013-01-01

    The sustainability of cultural heritage management of the resources is strongly related to support from local community via participation. It is evident that active community involvement can improve local residents’ quality of life based on better environment, social and economic conditions. However, there is little research into the question of whether the involvement of local community in heritage management derives from a genuine interest and desires to protect and conserve their local her...

  5. Community Involvement in Tourism Development: A Case Study of Lenggong Valley World Heritage Site

    OpenAIRE

    A. Khadar Nur Zafirah; Jaafar Mastura; Mohamad Diana

    2014-01-01

    This paper examines the empirical relationship between the economic impact and community involvement in the Lenggong Valley. Recommendations for improvement in development effectiveness through the development of a community centre for economic and social activities, with specific attention given to types of activity and community involvement stimulating the economic development in the Lenggong Valley. Heritage tourism development is a tourism in which arts, culture and heritage form a key at...

  6. The timing of drug funding announcements relative to elections: a case study involving dementia medications.

    Directory of Open Access Journals (Sweden)

    Sudeep S Gill

    Full Text Available BACKGROUND: Following initial regulatory approval of prescription drugs, many factors may influence insurers and health systems when they decide whether to add these drugs to their formularies. The role of political pressures on drug funding announcements has received relatively little attention, and elections represent an especially powerful form of political pressure. We examined the temporal relationship between decisions to add one class of drugs to publicly funded formularies in Canada's ten provinces and elections in these jurisdictions. METHODS: Dates of provincial formulary listings for cholinesterase inhibitors, which are drugs used to treat Alzheimer's disease and related dementias, were compared to the dates of provincial elections. Medical journal articles, media reports, and proceedings from provincial legislatures were reviewed to assemble information on the chronology of events. We tested whether there was a statistically significant increase in the probability of drug funding announcements within the 60-day intervals preceding provincial elections. RESULTS: Decisions to fund the cholinesterase inhibitors were made over a nine-year span from 1999 to 2007 in the ten provinces. In four of ten provinces, the drugs were added to formularies in a time period closely preceding a provincial election (P = 0.032; funding announcements in these provinces were made between 2 and 47 days prior to elections. Statements made in provincial legislatures highlight the key role of political pressures in these funding announcements. CONCLUSIONS: Impending elections appeared to affect the timing of drug funding announcements in this case study. Despite an established structure for evidence-based decision-making, drug funding remains a complex process open to influence from many sources. Awareness of such influences is critical to maintain effective drug policy and public health decision-making.

  7. Community Involvement in Tourism Development: A Case Study of Lenggong Valley World Heritage Site

    Directory of Open Access Journals (Sweden)

    A. Khadar Nur Zafirah

    2014-01-01

    Full Text Available This paper examines the empirical relationship between the economic impact and community involvement in the Lenggong Valley. Recommendations for improvement in development effectiveness through the development of a community centre for economic and social activities, with specific attention given to types of activity and community involvement stimulating the economic development in the Lenggong Valley. Heritage tourism development is a tourism in which arts, culture and heritage form a key attraction for visitors and it can be represented as an area of significant economic benefit to heritage sites. The tourism industry in Hulu Perak became more widespread after Lenggong Valley is recognized as a World Heritage Site. There is shown a positive effect on the development and economic prosperity.

  8. Principals’ involvement in the career development of female teachers: a case study in South Africa

    OpenAIRE

    Fourie, Anna W.; Van der Westhuizen, Philip C.; Mentz, Elsa

    2014-01-01

    Career planning is an important aspect of Human Resource Development and Management. This research is centered on the question as to whether school principals in South Africa fulfill their management role with respect to the career development of female teachers. The results indicate that principals rated their involvement in the career development of female educators relatively high, whereas female educators do not experience the principals to be supportive in terms of the identi...

  9. Using role analysis to plan for stakeholder involvement: a Wyoming case study

    Science.gov (United States)

    Burkardt, Nina; Ponds, Phadrea D.

    2006-01-01

    Prior to implementing laws and policies regulating water, wildlife, wetlands, endangered species, and recreation, natural resource managers often solicit public input. Concomitantly, managers are continually seeking more effective ways to involve stakeholders. In the autumn of 1999, the Wyoming Game and Fish Department sought to develop a state management plan for its portion of the Yellowstone grizzly bear (Ursus arctos horribilis) population if it was removed from the federal threatened species list. A key aspect of developing this plan was the involvement of federal, state, and local agencies, representatives from nongovernmental organizations, and citizens. Wyoming wildlife managers asked researchers from the United States Geological Survey to demonstrate how the Legal-Institutional Analysis Model could be used to initiate this process. To address these needs, we conducted similar workshops for a group of state and federal managers or staffers and a broad group of stakeholders. Although we found similarities among the workshop groups, we also recorded differences in perspective between stakeholder groups. The managers group acknowledged the importance of varied stakeholders but viewed the grizzly bear planning process as one centered on state interests, influenced by state policies, and amenable to negotiation. The other workshops identified many stakeholders and viewed the decision process as diffuse, with many opportunities for entry into the process. These latter groups were less certain about the chance for a successful negotiation. We concluded that if these assumptions and differences were not reconciled, the public involvement effort was not likely to succeed.

  10. A Case Study of Ethnic Minorities as Tourism Entrepreneurs: Their Involvement in Sustainable Tourism Development

    Directory of Open Access Journals (Sweden)

    Ceren Miral

    2013-07-01

    Full Text Available Most tourism activities excluding the e-tourism activities as matter of their nature (service taker and provider take place face to face between people. In addition tourism activities encourage bonding people both for tourists and the tourism services providers. Tourism creates cohesion for many different cultural groups. One of the cities in Turkey, Izmir is a good example with including too many culturally oriented groups such as Levantines, Greek, Jewish, rarely Armenians. In this paper there are two research questions are hold; how is being the other (ethnic minority as tourism entrepreneurs in tourism industry in Izmir and their involvement in sustainable tourism development is investigated and if tourism activities help connecting different cultural groups together and closer is investigated. So regarding these research questions, the research methodology in this paper is qualitative. For that reason, semi structured interview technique is applied to people are belong to different cultural groups and identities whom entrepreneurs in tourism industry. Semi structured interview technique is a commonly used an interview method depending on providing deep understanding of participants` perceptions, thoughts and behaviors. In general, understanding of the other brings feeling respect to others` cultural beliefs and lifestyle and this will make peace and harmony to where they live together. As a result, with the light of these research questions being the other entrepreneurship in sustainable tourism development in Izmir is evaluated. Furthermore, in this research is tried to indicate the advantageous and disadvantageous and importance of different cultural groups for sustainable tourism development

  11. Considering the air quality impacts of bioenergy crop production: a case study involving Arundo donax.

    Science.gov (United States)

    Porter, William C; Barsanti, Kelley C; Baughman, Eowyn C; Rosenstiel, Todd N

    2012-09-01

    The expanding production of bioenergy crops may impact regional air quality through the production of volatile organic compounds such as isoprene. To investigate the effects of isoprene-emitting crops on air quality, specifically ozone (O(3)) and secondary organic aerosol (SOA) formation, we performed a series of model runs using the Weather Research and Forecasting model with Chemistry (WRF/Chem) coupled with the Model of Emissions of Gases and Aerosols from Nature (MEGAN) simulating a proposed cropland conversion to the giant cane Arundo donax for biomass production. Cultivation of A. donax in the relatively clean air of northeastern Oregon resulted in an average increase in 8 h O(3) levels of 0.52 ppb, while SOA was largely unaffected (<+0.01 μg m(-3)). Conversions in U.S. regions with reduced air quality (eastern Texas and northern Illinois) resulted in average 8 h O(3) increases of 2.46 and 3.97 ppb, respectively, with daily increases up to 15 ppb in the Illinois case, and daytime SOA increases up to 0.57 μg m(-3). While cultivation of isoprene-emitting bioenergy crops may be appropriate at some scales and in some regions, other areas may experience increased O(3) and SOA, highlighting the need to consider isoprene emissions when evaluating potential regional impacts of bioenergy crop production.

  12. Learning through Political Participation: A Case Study of Spanish Elders Involved in Political Organizations

    Science.gov (United States)

    Serrat, Rodrigo; Petriwskyj, Andrea; Villar, Feliciano; Warburton, Jeni

    2016-01-01

    Older people's civic participation contributes to community development while at the same time providing opportunities for personal growth in later life. One important dimension of civic participation that has been largely underexplored is informal learning. The aim of this study is to explore the learnings experienced by Spanish older people…

  13. How to involve stakeholders in fisheries management : a country case study in Trinidad and Tobago

    NARCIS (Netherlands)

    Soma, K.

    2003-01-01

    The main purpose of this study is to show how the analytic hierarchy process (AHP) methodology can be applied to prepare and facilitate desired changes which the fishery sector with its stakeholders face. This is shown by an application of the AHP methodology in the shrimp fishery sector in Trinidad

  14. The variability of processes involved in transgene dispersal - case studies from Brassica and related genera

    DEFF Research Database (Denmark)

    Bagger Jørgensen, Rikke; Hauser, Thure Pavlo; D'Hertefeldt, T.;

    2009-01-01

    Background, aim, and scope We strive to predict consequences of genetically modified plants (GMPs) being cultivated openly in the environment, as human and animal health, biodiversity, agricultural practise and farmers’ economy could be affected. Therefore, it is unfortunate that the risk...... of results from gene-flow analysis. Main features Many independent experiments were performed on the individual processes in gene flow. The results comprise information both from laboratory, growth chambers and field trials, and they were generated using molecular or phenotypic markers and analysis......, pharmaceutical genes). This calls for a thorough risk assessment. However, in Brassica, the limited and uncertain knowledge on gene flow is an obstacle to this. Modelling of gene flow should be optimised, and modelling outputs verified in targeted field studies and at the landscape level. Last but not least...

  15. Student involvement as a vehicle for empowerment: a case study of the student platform for engineering education development

    KAUST Repository

    Delaine, David A.

    2010-08-01

    This paper examines the mission, structure and outputs of one organisation, the Student Platform for Engineering Education Development (SPEED), as a case study for how student-led organisations can use student involvement to promote and sustain student self-efficacy in an academic field. SPEED attracts young people to engineering through student participation in engineering education (EE). SPEED is a global, non-profit student organisation that functions as an interdisciplinary network to diversify dialogue, stimulate change and impact the development of EE and its effect on society. SPEED is directly attracting young people to engineering in various ways: the organisation of its keynote event, the Global Student Forum; facilitating interactions between globally minded, socially inclined engineers with aspirations to change the world; and through the global dissemination of SPEED\\'s work and practices through broad and relevant channels. Short-term outcomes are highlighted here. This case study can serve as a model for student engagement and involvement in other disciplines. © 2010 SEFI.

  16. Case Studies

    International Nuclear Information System (INIS)

    Proven options available to Sri Lanka for large scale electricity generation in the future are coal-fired thermal, oil-fired thermal and Nuclear. Four case studies for groups participated are indicated. Case study for group 1 is comparison of the three options by taking into consideration the capital and recurrent expenditure involved. Environmental effects of the three options are also given. Case study for group 2 is economic comparison of three renewable energy based power generation system. Case study for group 3 is based on energy conservation, efficiency, improvement and demand management. Assuming that a continuous saving of 20 MW of demand from 1996 onwards is effective two projects are suggested to achieve this result. Case study for group 4 is a feasibility study for hydro power development of the Kukule Ganga (river) in Sri Lanka. Participants are required to evaluate one of the three optional development concepts which are technically feasible

  17. Chronic eosinophilic pneumonia involving with mediastinal lymph nodes: radiologic study of three cases. Neumonia eosinofila cronica asociada a adenopatias mediastinicas: estudio radiologico de tres casos

    Energy Technology Data Exchange (ETDEWEB)

    Calvo Garcia, A.; Gordillo Gutierrez, I.; Guembe Urtiaga, P. (Hospital Gregorio Maraon, Madrid (Spain))

    1994-01-01

    Chronic eosinophilic pneumonia (CEP) is an uncommon disorder in our setting. Chest x-ray is essential to diagnosis. To date, we have found only three reported cases in which mediastinal lymph nodes were involved. We present three additional cases with standard thoracic study. (Author)

  18. A Clinicopathologic Study of 24 Cases of Systemic Mastocytosis Involving the Gastrointestinal Tract and Assessment of Mucosal Mast Cell Density in Irritable Bowel Syndrome and Asymptomatic Patients

    OpenAIRE

    Doyle, Leona A.; Sepehr, Golrokh J.; Hamilton, Matthew J; Akin, Cem; Castells, Mariana C.; Hornick, Jason L.

    2014-01-01

    Counting mast cells in gastrointestinal (GI) mucosal biopsies is becoming an increasingly common practice. The primary reason for this exercise is to evaluate for possible involvement by systemic mastocytosis (SM). However, the features of mastocytosis in GI biopsies are not well described. In addition, recent studies have suggested that increased mast cells may be involved in the pathogenesis of some cases of diarrhea-predominant irritable bowel syndrome (IBS); the term “mastocytic enterocol...

  19. National strategy for service user involvement in the Irish health services: a case study analysis of policy implementation

    OpenAIRE

    McEvoy, Rachel Margaret

    2014-01-01

    National and international health policies recognise that communities should be centrally involved in shaping primary healthcare services. Using Normalisation Process Theory (NPT) this study is designed to critically explore the levers and barriers to implementing community participation in primary healthcare as a routine way of working in the Health Service Executive (HSE). A qualitative systematic review of peer-reviewed literature using NPT was completed, as was a review of the ‘service...

  20. Foreign intervention in medical education: a case study of the Rockefeller Foundation's involvement in a Thai medical school.

    Science.gov (United States)

    Donaldson, P J

    1976-01-01

    A case study of the process of foreign intervention in medical education in the developing world is presented. Material collected from the Rockefeller Foundation Archives on a Foundation program in Thailand is used to analyze the conditions under which foreign agencies and their personnel intervene in the development of medical professionals in the Third World and to study the problems that may occur as a result of such intervention. The importance of value consensus and the competitive advantage foreigners have in the marketing of professional models are highlighted as reasons for the diffusion of Western models of medical education throughout the developing world.

  1. Foreign intervention in medical education: a case study of the Rockefeller Foundation's involvement in a Thai medical school.

    Science.gov (United States)

    Donaldson, P J

    1976-01-01

    A case study of the process of foreign intervention in medical education in the developing world is presented. Material collected from the Rockefeller Foundation Archives on a Foundation program in Thailand is used to analyze the conditions under which foreign agencies and their personnel intervene in the development of medical professionals in the Third World and to study the problems that may occur as a result of such intervention. The importance of value consensus and the competitive advantage foreigners have in the marketing of professional models are highlighted as reasons for the diffusion of Western models of medical education throughout the developing world. PMID:939621

  2. How are clinicians involved in EHR planning? A process analysis case study of a region in Denmark.

    Science.gov (United States)

    Høstgaard, Anna Marie; Bertelsen, Pernille; Nøhr, Christian

    2010-01-01

    Experience shows that to achieve a successful implementation of EHR clinicians must obtain joint ownership of the decisions made during the EHR-process. The EHR planning process in the Region of North Jutland, Denmark was studied with the aim of answering the question; "Why are not all Danish physicians overjoyed by the introduction of EHR? A case study was carried out from Oct. 2003 till April 2006 using process analysis. The EHR project management's strategy meant that there was no workload reduction. This was seen as one of the main barriers for the physicians to achieve real influence. History shows that clinician's on the one hand and administrators on the other have different perceptions of the purpose of the patient record and that they both have struggled to influence this definition. To date, the administrators have won the battle. This was the major reason for the approach chosen for the EHR planning process in North Jutland, Denmark. It explains the conditions made available for the physicians, which led to their role being reduced to clinical consultants--rather than real participants.

  3. Kidney involvement in a wegener granulomatosis case

    Directory of Open Access Journals (Sweden)

    Gioacchino Li Cavoli

    2012-01-01

    Full Text Available Wegener Granulomatosis is a systemic Anti-Neutrophil Cytoplasmic Autoantibody- associated Vasculitis, affecting small-to-medium vessels. Clinical presentation with simultaneous involvement of kidney and upper and lower respiratory tract is unusual. We report an instructive case of WG, analyzing clinical course, laboratory, and radiological features, kidney, lung, and larynx histological pictures. Besides renal biopsy, nephrology team performed larynx and lung biopsies because of unusual clinical presentation, computed tomography chest examination, and relevant malignancy risk regarding following immunosuppressant therapy.

  4. A case study on open innovation on Procter & Gamble. Part II: Co-creation and digital involvement

    Science.gov (United States)

    Agafitei, I. G.; Avasilcai, S.

    2015-11-01

    The first part of the present study case has pointed to the efforts directed by Procter & Gamble over time to keep close to its customers and the manner in which management has supported innovation within the company. Following the principles of disruptive innovation, the CEO of the company has set the goal for the company as to produce at least 50% of the innovations from external ideas. So, the aim of this paper is to continue to analyse the tools and the approach that P&G has taken in order to launch new products by partnering with other companies. Innovating by collaborating with external entities holding a highly specialized level of technology and engineering knowhow has been appreciated to contribute to the value creation process. In order to understand how open innovation strategy has worked for Procter & Gamble and which was the designated tool used to enrich the company with valuable input in order to develop products, we have taken a look at P&G's open innovation platform Connect + Develop.

  5. Maternal risk factors involved in specific congenital anomalies of the kidney and urinary tract : A case-control study

    NARCIS (Netherlands)

    Groen In 't Woud, Sander; Renkema, Kirsten Y; Schreuder, Michiel F; Wijers, Charlotte H W; van der Zanden, Loes F M; Knoers, Nine V A M; Feitz, Wout F J; Bongers, Ernie M H F; Roeleveld, Nel; van Rooij, Iris A L M

    2016-01-01

    BACKGROUND: Congenital anomalies of the kidney and urinary tract (CAKUT) comprise a heterogeneous group of birth defects with a variety of genetic and nongenetic factors suspected of involvement in the etiology. However, little is known about risk factors in specific CAKUT phenotypes. Therefore, we

  6. The use of public participation and economic appraisal for public involvement in large-scale hydropower projects: Case study of the Nam Theun 2 Hydropower Project

    International Nuclear Information System (INIS)

    Gaining public acceptance is one of the main issues with large-scale low-carbon projects such as hydropower development. It has been recommended by the World Commission on Dams that to gain public acceptance, public involvement is necessary in the decision-making process (). As financially-significant actors in the planning and implementation of large-scale hydropower projects in developing country contexts, the paper examines the ways in which public involvement may be influenced by international financial institutions. Using the case study of the Nam Theun 2 Hydropower Project in Laos, the paper analyses how public involvement facilitated by the Asian Development Bank had a bearing on procedural and distributional justice. The paper analyses the extent of public participation and the assessment of full social and environmental costs of the project in the Cost-Benefit Analysis conducted during the project appraisal stage. It is argued that while efforts were made to involve the public, there were several factors that influenced procedural and distributional justice: the late contribution of the Asian Development Bank in the project appraisal stage; and the issue of non-market values and discount rate to calculate the full social and environmental costs. - Highlights: ► Public acceptance in large-scale hydropower projects is examined. ► Both procedural and distributional justice are important for public acceptance. ► International Financial Institutions can influence the level of public involvement. ► Public involvement benefits consideration of non-market values and discount rates.

  7. Involving Older Adults in the Technology Design Process: A Case Study on Mobility and Wellbeing in the Built Environment.

    Science.gov (United States)

    Swallow, David; Petrie, Helen; Power, Christopher; Lewis, Andrew; Edwards, Alistair D N

    2016-01-01

    Older adults benefit from unstructured, lifestyle-based activity that can be carried out in people's houses, neighbourhoods, and the built environment. Technological solutions may support physical activity and encourage wellbeing. To ensure such technology is suitable for, and usable by, older adults, it is crucial they are involved in all stages of design. Participatory design methodologies facilitate collaboration and engagement with potential users. We examine the suitability of participatory design for collaborating and engaging with older adults. Participatory design workshops were conducted with 33 older adults in the UK with the aim of designing mobile applications to support and promote physical activity and wellbeing in the built environment. As well as summarising the outcome of these workshops, the paper outlines several methodological issues relating to the suitability of participatory design for involving older adults in the technology design process. PMID:27534357

  8. A clinicopathologic study of 24 cases of systemic mastocytosis involving the gastrointestinal tract and assessment of mucosal mast cell density in irritable bowel syndrome and asymptomatic patients.

    Science.gov (United States)

    Doyle, Leona A; Sepehr, Golrokh J; Hamilton, Matthew J; Akin, Cem; Castells, Mariana C; Hornick, Jason L

    2014-06-01

    Counting mast cells in gastrointestinal (GI) mucosal biopsies is becoming an increasingly common practice. The primary reason for this exercise is to evaluate for possible involvement by systemic mastocytosis (SM). However, the features of mastocytosis in GI biopsies are not well described. In addition, recent studies have suggested that increased mast cells may be involved in the pathogenesis of some cases of diarrhea-predominant irritable bowel syndrome (IBS); the term "mastocytic enterocolitis" has been proposed for such cases. As the baseline mast cell density in colonic biopsies from normal patients has not been established in large cohorts, there is no widely accepted threshold for what constitutes increased mucosal mast cells. The aims of this study were (1) to determine the utility of GI biopsies for the diagnosis of SM, (2) to characterize the clinical, histologic, and immunohistochemical features of mastocytosis in the GI tract, (3) to determine mast cell density in normal colonic mucosa from a large cohort of asymptomatic patients, and (4) to compare these findings with those from patients with diarrhea-predominant IBS. Twenty-four patients with SM involving the GI tract, 100 asymptomatic patients, and 100 patients with IBS (the latter 2 groups with histologically normal colonic biopsies) were included. For the mastocytosis group, 107 biopsies (70 involved by mastocytosis; 67 mucosal, 3 liver) from 20 women and 4 men were evaluated (median age 59 y). The most commonly involved site was the colon (19 patients, 95%), followed by ileum (86%), duodenum (80%), and stomach (54%). In 16 cases (67%), the first diagnosis of SM was made on the basis of GI biopsies. Seventeen patients had documented cutaneous mastocytosis. Fifteen of 17 patients who underwent bone marrow biopsy had marrow involvement by SM. Eighteen patients had indolent disease, and 6 had aggressive disease (including all 3 with liver involvement). The most common GI symptom was diarrhea, followed

  9. Airline Brand Loyalty: A case study involving the three airlines, - SAS, Norwegian and Widerøe

    OpenAIRE

    Shrestha, Basant Raj

    2014-01-01

    1.0 Abstract The general object of this study is to explore the airline brand loyalty. The primary objective of this study is to explore the nature of consumer loyalty and its major determinants with respect to the three airlines - SAS, Norwegian and Widerøe; analyze the data concerning relationships between consumers' attitude, habit, satisfaction and loyalty and identify the differences concerning attitude, habit, satisfaction, loyalty and factors (service, safety, comfort, luggage a...

  10. The involvement of family in child protection cases in Iceland

    OpenAIRE

    Anni Haugen; Sigrún Yrja Klörudóttir

    2015-01-01

    The aim of this study is to examine the involvement of families in child protection cases in Iceland, as well as to shed light on the attitudes of child protection workers on the importance of including families while working on child protection cases. The study is part of an international comparative analysis called: Social Work with Families: Social Workers’ Constructions of Family in Professional Practice. This article only addresses the Icelandic segment of the research. In the study, qua...

  11. Using combined eye tracking and word association in order to assess novel packaging solutions: A case study involving jam jars

    NARCIS (Netherlands)

    Piqueras Fiszman, B.; Velasco, C.; Salgado, A.; Spence, C.

    2013-01-01

    The present study utilized the techniques of eye tracking and word association in order to collect attentional information and freely-elicited associations from consumers in response to changing specific attributes of the product packaging (jam jars). We assessed the relationship between the data ob

  12. IMPLEMENTATION OF A PROJECT MANAGEMENT OFFICE IN A PUBLIC SECTOR ORGANIZATION: A CASE STUDY INVOLVING A SANITATION INSTITUTION

    Directory of Open Access Journals (Sweden)

    José Carlos Esquierro

    2014-01-01

    Full Text Available This paper proposes recommendations for improving the implementation of a Project Management Office (PMO in a government organization. Such organizations can face uncertainties due to unpredicted and unexpected environmental events. The methodology used here was based on review of the literature, experience of the authors, and analysis of the process to be employed to create a PMO in the Department of Municipal Water and Sewage Systems (SEMAE, Brazil. This study aims to show how implementing a PMO can ensure proper management of strategic projects related to conservation of water resources. The PMO plays an important role in the implementation of strategic projects for public sanitation. This study also shows that the effectiveness of actions taken by the PMO is strongly influenced by how this process is implemented.

  13. The Influence external signals on perceived quality and purchase intention products of high involvement (case study: Laptop)

    OpenAIRE

    MOHSEN NAZARI; ROGHAYEH REZAEE ARAB

    2014-01-01

    Nowadays, increasing competition in supplying and complexity of products caused information asymmetry between buyers and manufacturers that will eventually lead to adverse selection by purchasers. Thus, the role of external signals that are independent of the actual features of products become more important in quality perception and purchase intention of consumers. In this study, the effect of external signal (price, brand, Store brand, advertising, packaging, country of origin, friends, pre...

  14. Implementation of a Project Management Office in a Public Sector Organization: A Case Study Involving a Sanitation Institution

    OpenAIRE

    José Carlos Esquierro; André Bittencourt do Valle; Carlos Alberto Pereira Soares; Dácio Castro Vivas

    2014-01-01

    This paper proposes recommendations for improving the implementation of a Project Management Office (PMO) in a government organization. Such organizations can face uncertainties due to unpredicted and unexpected environmental events. The methodology used here was based on review of the literature, experience of the authors, and analysis of the process to be employed to create a PMO in the Department of Municipal Water and Sewage Systems (SEMAE), Brazil. This study aims to show how implementin...

  15. IMPLEMENTATION OF A PROJECT MANAGEMENT OFFICE IN A PUBLIC SECTOR ORGANIZATION: A CASE STUDY INVOLVING A SANITATION INSTITUTION

    OpenAIRE

    José Carlos Esquierro; André Bittencourt Valle; Carlos Alberto Pereira Soares; Dácio Castro Vivas

    2014-01-01

    This paper proposes recommendations for improving the implementation of a Project Management Office (PMO) in a government organization. Such organizations can face uncertainties due to unpredicted and unexpected environmental events. The methodology used here was based on review of the literature, experience of the authors, and analysis of the process to be employed to create a PMO in the Department of Municipal Water and Sewage Systems (SEMAE), Brazil. This study aims to show how implementin...

  16. The importance of large scale flood over the regular sedimentation in delta development: A case study involving Wax lake delta

    Science.gov (United States)

    Ullah, M. S.; Kolker, A.; Li, C.

    2011-12-01

    It has been widely hypothesized that catastrophic floods can play an important role in the development of a young and growing delta. This study examines the nature and rate of sediment deposition in the Wax lake delta in the Atchafalaya Basin of Louisiana during the Mississippi River flood of from April, 2011 to June, 2011. We hypothesize that the deposition rate that results from large scales floods in the Mississippi/Atchafalaya river outlets have a greater impact in the Wax lake delta development than the deposition rates that result from typical yearly sedimentation. Preliminary results from the cosmogenic 7Be counts from sediment collected from the delta show distinct regional and local sediment deposition patterns during the flood, and rates that are significantly higher when compared to the sedimentation rate of the last few decades. This application of cosmogenic 7Be to distinguish the sediment deposition rate provides a first-order understanding of the deltaic evolution and stratigraphic sequence development in a high-discharge setting.

  17. Where do neurologists look when viewing brain CT images? An eye-tracking study involving stroke cases.

    Directory of Open Access Journals (Sweden)

    Hideyuki Matsumoto

    Full Text Available The aim of this study was to investigate where neurologists look when they view brain computed tomography (CT images and to evaluate how they deploy their visual attention by comparing their gaze distribution with saliency maps. Brain CT images showing cerebrovascular accidents were presented to 12 neurologists and 12 control subjects. The subjects' ocular fixation positions were recorded using an eye-tracking device (Eyelink 1000. Heat maps were created based on the eye-fixation patterns of each group and compared between the two groups. The heat maps revealed that the areas on which control subjects frequently fixated often coincided with areas identified as outstanding in saliency maps, while the areas on which neurologists frequently fixated often did not. Dwell time in regions of interest (ROI was likewise compared between the two groups, revealing that, although dwell time on large lesions was not different between the two groups, dwell time in clinically important areas with low salience was longer in neurologists than in controls. Therefore it appears that neurologists intentionally scan clinically important areas when reading brain CT images showing cerebrovascular accidents. Both neurologists and control subjects used the "bottom-up salience" form of visual attention, although the neurologists more effectively used the "top-down instruction" form.

  18. The use of conspicuity aids by cyclists and risk of crashes involving other road users: a protocol for a population based case-control study

    Directory of Open Access Journals (Sweden)

    Coupland Carol

    2010-01-01

    Full Text Available Abstract Background Regular cycling has been shown to improve health and has a role in tackling the threats posed by obesity and inactivity. Cycle collisions, particularly those involving motorised vehicles, can lead to significant mortality and morbidity and are currently a barrier to wider uptake of cycling. There is evidence that the conspicuity of cyclists is a factor in many injury collisions. Low-cost, easy to use retro-reflective and fluorescent clothing and accessories ('conspicuity aids' are available. Their effectiveness in reducing cycling collisions is unknown. The study is designed to investigate the relationship between the use of conspicuity aids and risk of collision or evasion crashes for utility and commuter cyclists in the UK. Methods/Design A matched case-control study is proposed. Cases are adult commuter and utility cyclists involved in a crash resulting from a collision or attempted evasion of a collision with another road user recruited at a UK emergency department. Controls are commuter and utility cyclists matched by journey purpose, time and day of travel and geographical area recruited at public and private cycle parking sites. Data on the use of conspicuity aids, crash circumstances, demographics, cycling experience, safety equipment use, journey characteristics and route will be collected using self-completed questionnaires and maps. Conditional logistic regression will be used to calculate adjusted odds ratios and 95% confidence intervals of the risk of a crash when using any item of fluorescent or reflective clothing or equipment. Discussion This study will provide information on the effectiveness of conspicuity aids in reducing the risk of injury to cyclists resulting from crashes involving other road users.

  19. Spouses’ involvement in older patients’ fast-track programmes during total hip replacement using case management intervention. A study protocol of the SICAM-trial

    DEFF Research Database (Denmark)

    Berthelsen, Connie Bøttcher; Kristensson, Jimmie

    2015-01-01

    Aim To present the protocol of a two-group quasi-experimental study of spouses’ involvement through case management (The SICAM-trial) in older patients’ fast-track programmes during total hip replacement. Background Patients in fast-track programmes are required to take an active part in their...... status, nutrition, pain, depression and healthcare consumptions; and for spouses: caregiver satisfaction and difficulties and anxiety. Conclusion The intervention will give further evidence on the need for relatives’ participation in the patients’ fast-track programmes and the results will contribute to...... education of the health professionals in their need to include relatives in fast-track programmes. The study was funded by the Novo Nordisk Foundation and the Regional Health Scientific Foundation of Sealand....

  20. The involvement of family in child protection cases in Iceland

    Directory of Open Access Journals (Sweden)

    Anni Haugen

    2015-07-01

    Full Text Available The aim of this study is to examine the involvement of families in child protection cases in Iceland, as well as to shed light on the attitudes of child protection workers on the importance of including families while working on child protection cases. The study is part of an international comparative analysis called: Social Work with Families: Social Workers’ Constructions of Family in Professional Practice. This article only addresses the Icelandic segment of the research. In the study, qualitative methods were used and three focus groups were conducted, in which the same three-step vignette about a child protection case was presented. The findings highlighted how difficult child protection workers found it to define the family. The main element is that family are those individuals closest to the child and connected to them through emotional ties, as Icelandic child protection workers seem to strive to involve family in child protection cases. However, there are signs which show that when working with more complicated cases the definition of a family becomes narrower, and involvement is restricted mostly to parents and grandparents. The findings also show that attitudes toward fathers differ from those toward mothers. The mother is expected to support and create security for the child, while the father is judged mostly on his violent behaviour and is not automatically regarded as providing support or actively taking responsibility for his child.

  1. Court Cases Involving Contracts for School Districts

    Science.gov (United States)

    Allen, L. Hank

    2011-01-01

    The purpose of this research was to analyze trends in the United States regarding contract disputes that exist in school districts. Court cases were identified at the state and federal level to determine the outcomes and the fact patterns of contract disputes. To gain the knowledge of how courts handle cases of contractual breach, contracts…

  2. Co-Producing Sustainability: Involving Parents and Civil Society in the Governance of School Meal Services. A Case Study from Pisa, Italy

    Directory of Open Access Journals (Sweden)

    Francesca Galli

    2014-03-01

    Full Text Available There is a rising awareness of the power of the public sector in enhancing sustainable consumption and production practices, in particular related to food procurement and its social, ethical, economical and environmental implications. School meal services have a high resonance in the debate on collective catering services because of the implications on the education to sustainable dietary habits and the orientation of the production system. This contribution focuses on the reciprocal relationship between professionals and users of school meal services as a driver to mobilize new resources—according to the theory of co-production—that steer service innovation and a shift towards more sustainable practices. We illustrate this through a case study on the school meal system in Pisa (Italy, where the Canteen Committee represents an institutional arena for participation and empowerment of actors that has gradually gained a central role in shaping this school meal service. Despite the challenges and obstacles, the institutionalized co-production of services allows consolidation of trust among key players and the introduction of innovations in the service, in the form of several projects oriented to sustainability which would not take place without the joint effort of actors involved, parents in the first place.

  3. Schwannomatosis Involving Peripheral Nerves: A Case Report

    OpenAIRE

    Kim, Dong Hun; Hwang, Jung Hwa; Park, Sung-Tae; Shin, Ji Hoon

    2006-01-01

    Schwannomatosis or neurilemmomatosis has been used to describe patients with multiple nonvestibular schwannomas with no other stigmata of neurofibromatosis type-2 (NF-2). In our case, schwannomatosis, multiple schwannomas were present in a 21-yr-old woman with no stigmata or family history of NF-1 or NF-2. She had no evidence of vestibular schwannoma or other intracranial tumors. Multiple peripheral tumors were found in the carotid space of the neck, and soft tissue of posterior shoulder, low...

  4. Cerebral involvement in pseudoxanthoma elasticum; case report

    Directory of Open Access Journals (Sweden)

    Eylem Değirmenci

    2013-08-01

    Full Text Available Pseudoxanthoma elasticum (PXE is a rarely seen connective tissue disease which is characterized by progressive fragmentation and calcification of elastic fibers. Generally it is characterized by cutaneus, ocular and vascular system involvement and neurological complications are usually secondary to vascular insufficiency. 43 years old male patient had a progressive dysarthria, ataxia and vision loss which started many years ago referred to our clinic. Loose skin was seen on bilateral his axillar region and neck with atrophic, pale viola macular lesions on his body. There was “angiloid streaks” on fundus examination and skin biopsy showed calcified degenerated elastic fibers on middle and deep dermis. Diffuse white matter lesions were determined on cranial imaging. To keep in mind the diagnosis of rare diseases would be helpful in early diagnosis and treatment, reducing and even preventing systemic complications.

  5. Paracoccidioidomycosis case series with and without central nervous system involvement

    Directory of Open Access Journals (Sweden)

    Vinicius Sousa Pietra Pedroso

    2012-10-01

    Full Text Available INTRODUCTION: Paracoccidioidomycosis (PCM is the most important systemic mycosis in South America. Central nervous system involvement is potentially fatal and can occur in 12.5% of cases. This paper aims to contribute to the literature describing eight cases of neuroparacoccidioidomycosis (NPMC and compare their characteristics with patients without neurological involvement, to identify unique characteristics of NPCM. METHODS: A cohort of 213 PCM cases was evaluated at the Infectious Diseases Clinic of the University Hospital, Federal University of Minas Gerais, Brazil, from October 1976 to August 2008. Epidemiological, clinical, laboratory, therapeutic and follow-up data were registered. RESULTS: Eight patients presented NPCM. The observed NPCM prevalence was 3.8%. One patient presented the subacute form of PCM and the other seven presented the chronic form of the disease. The parenchymatous form of NPCM occurred in all patients. 60% of the patients who proceeded from the north/ northeast region of Minas Gerais State developed NPCM. The neurological involvement of a mother and her son was observed. NPCM patients exhibited demographical and clinical profiles similar to what is described in the literature. When NPCM cases were compared to PCM patients, there were differences in relation to origin and positive PCM family history. CONCLUSIONS: The results corroborate the clinical view that the neurological findings are extremely important in the evaluation of PCM patients. Despite the limitations of this study, the differences in relation to patient's origins and family history point to the need of further studies to determine the susceptibility factors involved in the neurological compromise.

  6. Case Studies in Biology.

    Science.gov (United States)

    Zeakes, Samuel J.

    1989-01-01

    A case study writing exercise used in a course on parasitology was found to be a powerful learning experience for students because it involved discipline-based technical writing and terminology, brought the students in as evaluators, applied current learning, caused interaction among all students, and simulated real professional activities. (MSE)

  7. The Impact of Parent’s Socioeconomic Status on Parental Involvement at Home: A Case Study on High Achievement Indian Students of a Tamil School in Malaysia

    Directory of Open Access Journals (Sweden)

    Suresh Kumar N Vellymalay

    2012-08-01

    Full Text Available The current study focuses on the impact of parent’s socioeconomic status on parental involvement in their child’s education at home. Forty Indian students studying in one the best performance- based National Type Tamil Schools in the state of Kedah, Malaysia were chosen based on purposive sampling. The sample comprised 10 students from Year Two, 10 students from Year Three, 10 students from Year Four and 10 students from Year Five. Those were the high achievement students identified based on the previous final year school examination results. Questionnaires were used by the researcher to obtain quantitative data related to the parent’s socioeconomic background and their involvement strategies in their children’s education at home from the students’ parent. In addition, in-depth interviews with twenty students, that is, five students from each Year were conducted to gather information on their parent’s involvement. The findings of this study indicate that most parents are from a higher socioeconomic background and they show a high degree of involvement in most of the involvement strategies at home to ensure their child’s educational success. Moreover, the economic and academic capital among the middle-class parents serve to enhance their understanding and knowledge on the actual values that need to be placed on their child’s education. As a result, these children gain in terms of good skills, behaviour and values, all of which are crucial to their academic success.

  8. Langerhans cell histiocytosis with involvement of the pons: case report

    Energy Technology Data Exchange (ETDEWEB)

    Vourtsi, A. [Xatzopoulou, Athens (Greece)]|[Department of Radiology, University of Athens Medical School, Athens (Greece); Papadopoulos, A.; Moulopoulos, L.A.; Vlahos, L. [Department of Radiology, University of Athens Medical School, Athens (Greece); Xenellis, J. [Department of Otorhinolaryngology, University of Athens Medical School, Athens (Greece)

    1998-03-01

    Central nervous system involvement is uncommon in Langerhans cell histiocytosis. The suprasellar region is more frequently affected. There have been few reports of involvement of the brain parenchyma shown on CT or MRI. We present a case of involvement of the pons, showing marked contrast enhancement on MRI. (orig.) With 2 figs., 17 refs.

  9. Langerhans cell histiocytosis with involvement of the pons: case report

    International Nuclear Information System (INIS)

    Central nervous system involvement is uncommon in Langerhans cell histiocytosis. The suprasellar region is more frequently affected. There have been few reports of involvement of the brain parenchyma shown on CT or MRI. We present a case of involvement of the pons, showing marked contrast enhancement on MRI. (orig.)

  10. Paracoccidioidomycosis case series with and without central nervous system involvement

    OpenAIRE

    Vinicius Sousa Pietra Pedroso; Ana Claudia Lyon; Stanley de Almeida Araújo; Juliana Márcia Ribeiro Veloso; Enio Roberto Pietra Pedroso; Antônio Lucio Teixeira

    2012-01-01

    INTRODUCTION: Paracoccidioidomycosis (PCM) is the most important systemic mycosis in South America. Central nervous system involvement is potentially fatal and can occur in 12.5% of cases. This paper aims to contribute to the literature describing eight cases of neuroparacoccidioidomycosis (NPMC) and compare their characteristics with patients without neurological involvement, to identify unique characteristics of NPCM. METHODS: A cohort of 213 PCM cases was evaluated at the Infectious Diseas...

  11. Faculty Roles, Responsibilities, and Involvement in Campus Safety Initiatives as Perceived by Faculty and Administrators: A Case Study at a Large State University

    Science.gov (United States)

    Rollings, Meda Janeen

    2010-01-01

    The study addressed the problem of campus safety and the extent to which faculty and administrators are aware of institutional security policies. Further, the research compared perceptions of administrators and faculty regarding faculty awareness of and involvement in campus safety policy initiatives. The research sought to determine if the…

  12. The possible involvement of Mycobacterium avium ssp. paratuberculosis in the aetiology of Crohn's disease: a case control study in the Netherlands

    NARCIS (Netherlands)

    Herrewegh AAPM; Overduin P; Roholl PJM; Gielis FK; Robinson JE; Mahmmod N; Lieverse RJ; Robijn RJ; Zanden AGM van der; Soolingen D van; Dept of Medical Microbiology; Biomedics Scientific Consultancy; LIS; LPI

    2005-01-01

    A case control study was performed to investigate the possible role of Mycobacterium avium ssp. paratuberculosis (Map) in the aetiology of Crohn's disease (CD). Biopsy samples were collected from the ileum and colon of CD patients, Ulcerative Colitis (UC) patients and control persons. The biopsy sam

  13. Rotordynamic Stability Case Studies

    OpenAIRE

    Choudhury Pranabesh

    2004-01-01

    In this article case studies are presented involving rotordynamic instability of modern high-speed turbomachinery relating the field data to analytical methods. The studies include oil seal related field problems, instability caused by aerodynamic cross-coupling in high-pressure, high-speed compressors, and hydrodynamic bearing instability resulting in subsynchronous vibration of a high-speed turbocharger. It has been shown that the analytical tools not only help in problem diagnostics, bu...

  14. Neurosyphilis Involving Cranial Nerves in Brain Stem: 2 Case Reports

    Energy Technology Data Exchange (ETDEWEB)

    Jang, Ji Hye [Dept. of Radiology, Kyung Hee University College of Medicine, Seoul (Korea, Republic of); Choi, Woo Suk; Kim, Eui Jong [Dept. of Radiology, Kyung Hee University Hospital, Seoul (Korea, Republic of); Yoon, Sung Sang; Heo, Sung Hyuk [Dept. of Neurology, Kyung Hee University Hospital, Seoul (Korea, Republic of)

    2012-01-15

    Neurosyphilis uncommonly presents with cranial neuropathies in acute syphilitic meningitis and meningovascular neurosyphilis. We now report two cases in which the meningeal form of neurosyphilis involved cranial nerves in the brain stem: the oculomotor and trigeminal nerve.

  15. Ophaceous Gout Involving the Whole Spine: An Unusual Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Min Woo; Lee, Ji Hae; Cho, Woo Ho [Dept. of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul (Korea, Republic of)

    2012-02-15

    Gout is a relatively common, crystal deposition disease, in which monosodium urate crystals are deposited in joint and periarticular tissues of the extremities. Involvement of the spine is exceedingly rare. Most patients with spinal gout present with symptomatic spinal cord compression. Diffuse involvement of tophi deposition inside the spinal central canal has not been reported. We now present a case of chronic tophaceous gout with extensive spinal involvement that resulted in diffuse spinal cord compression and led to paraplegia.

  16. Langerhans cell histiocytosis involving central nervous system: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Won Jin; Park, Dong Woo; Lee, Seung Ro; Hahm, Chang Kok; Ju, Kyung Bin [Hanyang University College of Medicine, Seoul (Korea, Republic of); Kim, Sung Tae [Ulsan University College of Medicine, Seoul (Korea, Republic of)

    1997-01-01

    Langerhans cell histiocytosis(LCH) is a systemic disorder characterized by idiopathic proliferation of histiocytes in the reticuloendothelial system; CNS involvement outside the hypothalamus or pituitary gland is uncommon. We present a case of LCH involving the brainstem, cerebellum, and temporal lobes, and also showing hypothalamic involvement. The lesions were isointense or hypointense on T1WI and hyperintense on T2WI, and showed multifocal enhancing nodules on post-contrast CT and Gd-enhanced MRI.

  17. Langerhans cell histiocytosis involving central nervous system: a case report

    International Nuclear Information System (INIS)

    Langerhans cell histiocytosis(LCH) is a systemic disorder characterized by idiopathic proliferation of histiocytes in the reticuloendothelial system; CNS involvement outside the hypothalamus or pituitary gland is uncommon. We present a case of LCH involving the brainstem, cerebellum, and temporal lobes, and also showing hypothalamic involvement. The lesions were isointense or hypointense on T1WI and hyperintense on T2WI, and showed multifocal enhancing nodules on post-contrast CT and Gd-enhanced MRI

  18. Triple intussusception involving heterotopic pancreatic tissue: a case report

    OpenAIRE

    Sautot-Vial N; Steyaert H

    2009-01-01

    Abstract Introduction Intussusception involving heterotopic pancreatic tissue is a rare condition where a portion of the bowel telescopes into an adjacent segment with intraluminal pancreatic tissue as the lead point. Cases of heterotopic pancreas are most often described in the upper intestinal tract, particularly the stomach. Case presentation We present the case of a five-month-old boy of Caucasian ethnicity suffering acute abdominal pain and vomiting with an abdominal mass in the upper ri...

  19. Case Study: Writing a Journal Case Study

    Science.gov (United States)

    Prud'homme-Genereux, Annie

    2016-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue describes incorporating a journal article into the classroom by first converting it into a case study.

  20. Food Habits, Lifestyle Factors, and Risk of Prostate Cancer in Central Argentina: A Case Control Study Involving Self-Motivated Health Behavior Modifications after Diagnosis

    Directory of Open Access Journals (Sweden)

    Sandaly O. S. Pacheco

    2016-07-01

    Full Text Available Cancer is the second most important non-communicable disease worldwide and disproportionately impacts low- to middle-income countries. Diet in combination with other lifestyle habits seems to modify the risk for some cancers but little is known about South Americans. Food habits of Argentinean men pre- and post-diagnosis of prostate cancer (n = 326 were assessed along with other lifestyle factors. We studied whether any of the behaviors and risk factors for prostate cancer were found in men with other cancers (n = 394, compared with control subjects (n = 629. Before diagnosis, both cases reported a greater mean consumption of meats and fats and lower intakes of fruits, green vegetables, cruciferous vegetables, legumes, nuts, seeds, and whole grains than the controls (all p < 0.001. After diagnosis, cases significantly reduced the intake of meats and fats, and reported other dietary modifications with increased consumption of fish, fruits (including red fruits in prostate cancer, cruciferous vegetables, legumes, nuts, and black tea (all p < 0.001. Additional lifestyle aspects significantly predominant in cases included a reduced quality of sleep, emotional stress, low physical activity, tobacco smoking, alcohol consumption, living in rural areas, and being exposed to environmental contaminants. Argentinian men were predisposed to modify their unhealthy dietary habits and other lifestyle factors after cancer diagnosis.

  1. [A case of Sotos syndrome associated with peripheral nerve involvements].

    Science.gov (United States)

    Funakawa, I; Katoh, H; Hara, K; Yasuda, T; Terao, A

    1992-03-01

    A case of the Sotos syndrome associated with peripheral nerve involvements was reported. A 52-year-old male was admitted to Kawasaki Medical School Hospital because of gait disturbance, muscle atrophy, and weakness in both hands. This case was diagnosed as the Sotos syndrome based on the following symptoms and findings, acromegaloid features, hypertrophic changes in the hands and feet, a history of epileptic episodes, a low IQ, a normal growth hormone value, and no tumor lesion in the pituitary gland. Radiological examination disclosed a cauliflower-like appearance of the finger tips and thickness of the heel pads. Brain CT and MRI revealed diffuse mild brain atrophy. An electroencephalogram showed diffuse theta waves with sharp waves in the right parietal region. A needle electromyogram revealed neurogenic change in both upper and lower limbs. A nerve conduction study disclosed the carpal tunnel syndrome and cubital tunnel syndrome. These findings suggest that, as in the case of acromegaly, entrapment neuropathy and peripheral neuropathy can also be induced in the Sotos syndrome.

  2. Patient Complaint Cases in Primary Health Care: What Are the Characteristics of General Practitioners Involved?

    OpenAIRE

    Søren Birkeland; Rene dePont Christensen; Niels Damsbo; Jakob Kragstrup

    2013-01-01

    Background. Limited knowledge exists about factors increasing the risk of general practitioners becoming involved in a complaint case or getting disciplined in connection with a complaint case. Aim. The present study aimed to identify the general practitioner and practice characteristics associated with complaint cases and discipline. Methods. Information on general practitioners involved in complaint case decisions during one year (2007) was linked to Danish National register data on all gen...

  3. Going Beyond Common Drug Metabolizing Enzymes: Case Studies of Biotransformation Involving Aldehyde Oxidase, γ-Glutamyl Transpeptidase, Cathepsin B, Flavin-Containing Monooxygenase, and ADP-Ribosyltransferase.

    Science.gov (United States)

    Fan, Peter W; Zhang, Donglu; Halladay, Jason S; Driscoll, James P; Khojasteh, S Cyrus

    2016-08-01

    The significant roles that cytochrome P450 (P450) and UDP-glucuronosyl transferase (UGT) enzymes play in drug discovery cannot be ignored, and these enzyme systems are commonly examined during drug optimization using liver microsomes or hepatocytes. At the same time, other drug-metabolizing enzymes have a role in the metabolism of drugs and can lead to challenges in drug optimization that could be mitigated if the contributions of these enzymes were better understood. We present examples (mostly from Genentech) of five different non-P450 and non-UGT enzymes that contribute to the metabolic clearance or bioactivation of drugs and drug candidates. Aldehyde oxidase mediates a unique amide hydrolysis of GDC-0834 (N-[3-[6-[4-[(2R)-1,4-dimethyl-3-oxopiperazin-2-yl]anilino]-4-methyl-5-oxopyrazin-2-yl]-2-methylphenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide), leading to high clearance of the drug. Likewise, the rodent-specific ribose conjugation by ADP-ribosyltransferase leads to high clearance of an interleukin-2-inducible T-cell kinase inhibitor. Metabolic reactions by flavin-containing monooxygenases (FMO) are easily mistaken for P450-mediated metabolism such as oxidative defluorination of 4-fluoro-N-methylaniline by FMO. Gamma-glutamyl transpeptidase is involved in the initial hydrolysis of glutathione metabolites, leading to formation of proximate toxins and nephrotoxicity, as is observed with cisplatin in the clinic, or renal toxicity, as is observed with efavirenz in rodents. Finally, cathepsin B is a lysosomal enzyme that is highly expressed in human tumors and has been targeted to release potent cytotoxins, as in the case of brentuximab vedotin. These examples of non-P450- and non-UGT-mediated metabolism show that a more complete understanding of drug metabolizing enzymes allows for better insight into the fate of drugs and improved design strategies of molecules in drug discovery. PMID:27117704

  4. STUDY OF CARDIAC INVOLVEMENT IN DIPHTHERIA

    Directory of Open Access Journals (Sweden)

    Bala Raju Gundam

    2016-07-01

    Full Text Available BACKGROUND Diphtheria still endemic in many developing countries and is responsible for high case fatality. Myocardial involvement is a serious complication of diphtheria and diphtheria myocarditis frequently complicated by arrhythmias causes sudden death if not managed properly. So, early and adequate administration of Anti-Diphtheritic Serum (ADS and frequent monitoring particularly 24 hrs. ECG monitoring is helpful to detect any serious cardiac arrhythmias. METHODS A prospective study on patients who were culture positive diagnosed on the basis of WHO definition were treated and analysed in respect to homographic details, immunisation strategy, and clinical features with particular attention to myocarditis. RESULTS In the study, common age group affected by diphtheria was 5 to 10 years. Incidence of myocarditis more in same age group. Out of 64 patients with myocarditis, 23 patients died. CONCLUSION Incidence of diphtheria has increased in the recent years. Commonly effected age group is 5 to 10 years and most of them are presented with asymptomatic myocarditis. Symptomatic diphtheritic myocarditis has high mortality rate even with aggressive management. Patient who presented with either LBBB alone are with combination of other conduction of abnormalities has high mortality rate.

  5. Interaction of activity involvement and recreational location selection behavior in Lowland City: A case study of public parks in Saga City, Japan

    Institute of Scientific and Technical Information of China (English)

    IAMTRAKUL Pawinee; TEKNOMO Kardi; GE Jian; HOKAO Kazunori

    2005-01-01

    Public parks provide many benefits to the community as the representatives of green area. The allocation of public places plays an extremely important role in the daily lives of inhabitants especially for recreational use that could enhance the quality of life of residents in the vicinity. To understand park users' behavior is one of the most important prerequisites for assessing the participation in public service from the park users' point of view. The pattern of park utilization on location and activity selection are important elements in behavioral study, while the public parks topograph may also influence the typical user's behavior. Questionnaire survey on park utilization was used to investigate the interaction between activity involvement and recreational location with the use of linear discriminant analysis (LDA) model. The study found that public park users' behavior is influenced not only by social characteristics but also by the recreational activities and their specific location characteristics. We found that about 45 percent of park visitors are local residents living within a radius of 3 km preferred travel to parks near their residential area. This implies that location selection behavior is correlated with travel distance, travel time and travel cost. Visit frequencies and on site expenditures reflect the recreation behavior for different type of activities. The overall information can be usefully applied by decision makers to launch appropriate public policy in consistence with the useful results of this study.

  6. Leukemic meningitis involving the cauda equina: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dong Hyun; Kim, Ho Kyun; Lee, Young Hwan [School of Medicine, Catholic University of Daegu, Daegu (Korea, Republic of)

    2008-07-15

    The CNS involvement by leukemia may either be meningeal or parenchymal, although meningeal infiltration of leukemic cells, known as leukemic meningitis is more common. We report a case of leukemic meningitis involving the cauda equina in a patient with an acute lymphoblastic crisis which transformed from the chronic phase of chronic myeloid leukemia. An MR image revealed diffuse enlargement and peripheral ring enhancement of the nerve roots of the cauda equina.

  7. A rare case of segmental neurofibromatosis involving the sciatic nerve.

    Science.gov (United States)

    Trocchia, Aron; Reyes, Alma; Wilson, Jon; Les, Kimberly

    2010-05-01

    Segmental neurofibromatosis (NF-5) is an extremely rare variant of neurofibromatosis involving a single extremity without pathologic features beyond the midline. A case of segmental neurofibromatosis involving the sciatic nerve and its branches is presented with a detailed description of the patient's preoperative findings plus postoperative course through 1-year follow-up. Clinical, histologic, and genetic findings are given along with a brief review of the literature on segmental neurofibromatosis. Last, treatment options and postoperative care recommendations are provided. PMID:20567746

  8. Triple intussusception involving heterotopic pancreatic tissue: a case report

    Directory of Open Access Journals (Sweden)

    Sautot-Vial N

    2009-11-01

    Full Text Available Abstract Introduction Intussusception involving heterotopic pancreatic tissue is a rare condition where a portion of the bowel telescopes into an adjacent segment with intraluminal pancreatic tissue as the lead point. Cases of heterotopic pancreas are most often described in the upper intestinal tract, particularly the stomach. Case presentation We present the case of a five-month-old boy of Caucasian ethnicity suffering acute abdominal pain and vomiting with an abdominal mass in the upper right quadrant. Work-up including ultrasound scan confirmed the intussusception. Repeated attempts at radiological reduction and two laparoscopic procedures were performed within 24 hours, which eventually led to the diagnosis of a triple intussusception. Conclusion To our knowledge, such a case of triple intussusception involving isolated heterotopic pancreatic tissue is previously unreported.

  9. Involvement of Mycoplasma synoviae in Respiratory Distress Cases of Broilers

    Directory of Open Access Journals (Sweden)

    S. Ehtisham-ul-Haque*, S. U. Rahman, M. Siddique and A. S. Qureshi1

    2011-04-01

    Full Text Available Mycoplasma synoviae (MS is an important pathogen of poultry worldwide, causing respiratory tract infection and infectious synovitis in chickens and turkeys. The study was designed to detect M. synoviae through serology, culture isolation and polymerase chain reaction (PCR assay to document the involvement of MS infection in respiratory distress cases of broiler birds. The validated PCR assay amplifying the conserved gene region of 16SrRNA gene was applied for the detection of M. synoviae from culture as well as in clinical samples. The results indicated that 04 out of total 17 commercial broiler flocks showing respiratory distress signs were found positive with M. synoviae infection indicating 76.57% sero-positivity as, determined with rapid serum agglutination (RSA test. Out of 85 clinical specimens (collected from sero-positive birds; M. synoviae culture isolation was successfully attained in 36 (42.35% samples. Whereas, PCR test has detected 84 (98.82% positive cases. The prevalence of MS in broiler birds was observed maximum as measured through PCR. It is suggested that the true prevalence of MS may best be reflected by combining RSA and PCR test findings.

  10. `Cranach Inc.' A case study determining the nature and extent of Lucas Cranach the Elder's involvement in his industrious workshop using image processing

    Science.gov (United States)

    Lubashevsky, Ruth

    2015-06-01

    Lucas Cranach the Elder (LCE) (1472-1553) maintained an organized and highly efficient workshop, served as councilor in Wittenberg from 1519-1544, established a publishing house in 1520, held a pharmacy from 1520, and served as mayor of Wittenberg from 1537 to 1543. He was known as the 'swiftest of painters,' resulting in 1,000 surviving panel paintings, canvas paintings, drawings, and etchings in a career that spanned 53 years (1500-1553). Facing this astoundingly enormous oeuvre, the question that this paper seeks to answer is unavoidable: what was LCE's involvement in this oeuvre, which most is still attributed to him, in light of his many other time-consuming engagements? To answer this question, this paper becomes a study of stylistic comparisons of LCE's oeuvre, in order to assess, analyze and identify his style to determine whether all of the works attributed to him were indeed his own handiwork. Classifying LCE's style, together with the fact that he ran his workshop in factory-like conditions, supplying his apprentices with pigments, designs they could trace, copies, modelling versions, and patterns, making him an artist turned businessman, LCE becomes an artist who turned art into an industrial operation, earning the title 'Cranach Inc.' The conclusion of this paper will be based inter-alia on comparisons between Infra-red images and the visible paintings, in order to undermine the established attributions made to LCE.

  11. A Case of Secondary Syphilis With Liver and Kidney Involvement

    Institute of Scientific and Technical Information of China (English)

    LEI Shanchuan(雷山川); YU Yi(余艺); YE Yuhong(叶玉鸿)

    2002-01-01

    @@ SYPHILIS IS A chronic sexually transmitted diseasecaused by Treponum Pallidum spreading to the wholebody. Late Syphilis can encroach on most of the organs,but early syphilis has less damage to the internal organs.Here is a case of secondary syphilis with liver andkidney involvement reported as follows:

  12. [Henoch-Schonlein purpura involving the penis: a case report].

    Science.gov (United States)

    Croche Santander, Borja; Campos, Elena; Sánchez, Adela; Marcos, Laura; Díaz, Isabel; Toro, Cristóbal

    2016-08-01

    Schonlein-Henoch purpura accounts for the majority of cases of systemic vasculitis in children. Classical presentation is characterized by palpable purpura, glomerulonephritis, arthralgias and abdominal pain. Although genitourinary manifestations, in form of testicular and scrotal involvement, have been widely described, penile involvement remains an extremely rare complication. We report a case of a 6-year-old boy who presented with purpuric rash on the glans, prepuce and penile shaft, with painful edema in the penile region. He also had a 3-days history of fever, palpable purpuric rash on the buttocks and lower extremities along with right wrist pain. He was admitted with the diagnosis of Schonlein-Henoch purpura with penile involvement. After 2 days on oral steroids therapy (prednisone) a marked improvement was observed. PMID:27399026

  13. Food Habits, Lifestyle Factors, and Risk of Prostate Cancer in Central Argentina: A Case Control Study Involving Self-Motivated Health Behavior Modifications after Diagnosis.

    Science.gov (United States)

    Pacheco, Sandaly O S; Pacheco, Fabio J; Zapata, Gimena M J; Garcia, Julieta M E; Previale, Carlos A; Cura, Héctor E; Craig, Winston J

    2016-01-01

    Cancer is the second most important non-communicable disease worldwide and disproportionately impacts low- to middle-income countries. Diet in combination with other lifestyle habits seems to modify the risk for some cancers but little is known about South Americans. Food habits of Argentinean men pre- and post-diagnosis of prostate cancer (n = 326) were assessed along with other lifestyle factors. We studied whether any of the behaviors and risk factors for prostate cancer were found in men with other cancers (n = 394), compared with control subjects (n = 629). Before diagnosis, both cases reported a greater mean consumption of meats and fats and lower intakes of fruits, green vegetables, cruciferous vegetables, legumes, nuts, seeds, and whole grains than the controls (all p cancer), cruciferous vegetables, legumes, nuts, and black tea (all p sleep, emotional stress, low physical activity, tobacco smoking, alcohol consumption, living in rural areas, and being exposed to environmental contaminants. Argentinian men were predisposed to modify their unhealthy dietary habits and other lifestyle factors after cancer diagnosis. PMID:27409631

  14. Aberrations Involving Chromosome 1 as a Possible Predictor of Odds Ratio for Colon Cancer--Results from the Krakow Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Aleksander Galas

    Full Text Available There is still an open question how to predict colorectal cancer risk before any morphological changes appear in the colon.The purpose was to investigate aberrations in chromosomes 1, 2 and 4 in peripheral blood lymphocytes analyzed by fluorescence in situ hybridization technique as a tool to assess the likelihood of colorectal cancer.A hospital-based case-control study included 20 colon cancer patients and 18 hospital-based controls. Information about potential covariates was collected by interview. The frequency of stable and unstable chromosome aberrations in chromosome 1, 2 and 4 was assessed by fluorescence in situ hybridization technique.Colorectal cancer patients, as compared to controls, had a relatively higher frequency of chromosome 1 translocations (median: 3.5 versus 1.0 /1000 cells, p = 0.006, stable aberrations (3.8 versus 1.0 /1000 cells, p = 0.007 and total aberrations (p = 0.009. There were no differences observed for chromosomes 2 and 4. Our results showed an increase in the odds of having colon cancer by about 50-80% associated with an increase by 1/1000 cells in the number of chromosome 1 aberrations.The results revealed that the frequency of chromosomal aberrations, especially translocations in chromosome 1, seems to be a promising method to show a colon cancer risk. Additionally, our study suggests the reasonableness of use of biomarkers such as chromosome 1 aberrations in peripheral blood lymphocytes in screening prevention programs for individuals at higher colon cancer risk to identify those who are at increased risk and require more frequent investigations, e.g. by sigmoidoscopy.

  15. Different pathways are involved in the enhancement of photosynthetic rate by sodium bisulfite and benzyladenine, a case study with strawberry (Fragaria x Ananassa Duch) plants

    NARCIS (Netherlands)

    Guo, Y.P.; Peng, Y.; Lin, M.L.; Guo, D.P.; Hu, M.J.; Shen, Y.K.; Li, D.Y.; Zheng, S.J.

    2006-01-01

    In order to understand the pathway involved in the chemical enhancement of photosynthetic rate, sodium bisulfite (NaHSO3) and benzyladenine (BA), a growth regulator, were applied to strawberry plants. The influence of these compounds on gas exchange and millisecond delayed light emission (ms-DLE) wa

  16. Project management case studies

    CERN Document Server

    Kerzner, Harold R

    2013-01-01

    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  17. A case of extensive synovial involvement by tophaceous gout

    Directory of Open Access Journals (Sweden)

    Nausheen Khan

    2010-12-01

    Full Text Available Gout is the most common form of microcrystal arthropathy that results in deposition of uric acid crystals in and around the joints and soft tissues. The most common cause is decreased uric acid clearance by the kidneys. The radiological manifestations of gout are generally well known and have remained unchanged. We describe a case of chronic tophaceous gout with diffuse extensive involvement of synovium around the knees bilaterally.

  18. [Monomelic segmental amyotrophy: a Spanish case involving the leg].

    Science.gov (United States)

    Moreno Martinez, J M; Garcia de la Rocha, M L; Martin Araguz, A

    1990-01-01

    A 65-year old male presented with selective amyotrophy of the right lower limb which, after a progressive course of some months, had stabilized 12 years previously. Physical examination showed amyotrophy involving the gastrocnemius and the quadriceps extensor femoris without sensory impairment. EMG suggested motor neuron disease. This case meets Hirayama and Serratrice's criteria for benign chronic monomelic amyotrophy. We support the hypothesis of a casual vascular factor, as proposed by Hirayama. PMID:2204988

  19. Stakeholder involvement in stages of a participatory process illustrated in interior design cases

    DEFF Research Database (Denmark)

    Vink, Peter; van Rhijn, Gu; Seim, Rikke

    2008-01-01

    In a previous study (Vink et al., 2008) an overview was made of the involvement of different stakeholders in a participatory design process. In this paper this overview was used to describe four participatory design cases focused on improvising productivity, health, and comfort by interior design....... It appeared that this overview is useful to describe the involvement in participatory interior design projects. However, it can only serve as an initial benchmark as much is dependent on the specific case at hand....

  20. Involving stakeholders in policy research should not imply that they control the problem definition: lessons from a case study on new analgesics

    NARCIS (Netherlands)

    M. Moret-Hartman; G.J. van der Wilt; J. Grin

    2009-01-01

    The Dutch Health Care Insurance Board (HCIB) commissions research to guide their policy recommendations. However, the studies conducted do not always yield relevant information. This may result from differences in problem definitions held by the HCIB and target populations. To compensate these probl

  1. The Value of a "Core" Business--A Case Study of the Involvement of an Australian University in Vietnam: 1993-1998.

    Science.gov (United States)

    Pidgeon, John; Di Virgilio, Patricia

    1999-01-01

    Describes how two dovetailing processes led Swinburne University of Technology of Melbourne, Australia, to the setting up of business studies programs in Vietnam: the increased need to make higher education in Australia more cost efficient and the Vietnamese government's decision to move to a market-based economy. Thus, the Vietnamese government…

  2. A history of the working group to address Los Alamos community health concerns. A case study of community involvement and risk communication

    International Nuclear Information System (INIS)

    In May 1991, at a Department of Energy (DOE) public hearing at Los Alamos, New Mexico, a local artist claimed there had been a recent brain tumor cluster in a small Los Alamos neighborhood. He suggested the cause was radiation from past operations of Los Alamos National Laboratory. Data from the Laboratory's extensive environmental monitoring program gave no reason to believe this charge to be true but also could not prove it false. These allegations, reported in the local and regional media, alarmed the community and revealed an unsuspected lack of trust in the Laboratory. Having no immediate and definitive response, the Laboratory offered to collaborate with the community to address this concern. The Los Alamos community accepted this offer and a joint Community-Laboratory Working Group met for the first time 29 days later. The working group set as its primary goal the search for possible carcinogens in the local environment. Meanwhile, the DOE announced its intention to fund the New Mexico Department of Health to perform a separate and independent epidemiological study of all Los Alamos cancer rates. In early 1994, after commissioning 17 environmental studies and meeting 34 times, the working group decided that the public health concerns had been resolved to the satisfaction of the community and voted to disband. This paper tells the story of the artist and the working group, and how the media covered their story. It summarizes the environmental studies directed by the working group and briefly reviews the main findings of the epidemiology study. An epilogue records the present-day recollections of some of the key players in this environmental drama

  3. A history of the working group to address Los Alamos community health concerns - A case study of community involvement and risk communication

    Energy Technology Data Exchange (ETDEWEB)

    Harry Otway; Jon Johnson

    2000-01-01

    In May 1991, at a Department of Energy (DOE) public hearing at Los Alamos, New Mexico, a local artist claimed there had been a recent brain tumor cluster in a small Los Alamos neighborhood. He suggested the cause was radiation from past operations of Los Alamos National Laboratory. Data from the Laboratory's extensive environmental monitoring program gave no reason to believe this charge to be true but also could not prove it false. These allegations, reported in the local and regional media, alarmed the community and revealed an unsuspected lack of trust in the Laboratory. Having no immediate and definitive response, the Laboratory offered to collaborate with the community to address this concern. The Los Alamos community accepted this offer and a joint Community-Laboratory Working Group met for the first time 29 days later. The working group set as its primary goal the search for possible carcinogens in the local environment. Meanwhile, the DOE announced its intention to fund the New Mexico Department of Health to perform a separate and independent epidemiological study of all Los Alamos cancer rates. In early 1994, after commissioning 17 environmental studies and meeting 34 times, the working group decided that the public health concerns had been resolved to the satisfaction of the community and voted to disband. This paper tells the story of the artist and the working group, and how the media covered their story. It summarizes the environmental studies directed by the working group and briefly reviews the main findings of the epidemiology study. An epilogue records the present-day recollections of some of the key players in this environmental drama.

  4. A case of Crohn's disease involving the gallbladder

    Institute of Scientific and Technical Information of China (English)

    Akira Andoh; Yoshihiro Endo; Ryoji Kushima; Kazunori Hata; Tomoyuki Tsujikawa; Masaya Sasaki; Eiji Mekata; Toru Tani; Yoshihide Fujiyama

    2006-01-01

    Crohn's disease is well known to affect any part of the gastrointestinal tract including the oral cavity and anus.Various extraintestinal complications have been reported in Crohn's disease, but extraintestinal involvement characterized by granulomatous lesions is uncommon. Here, we have reported a case about the involvement of the gallbladder in Crohn's disease. A 33-year-old woman was diagnosed having panperitonitis due to intestinal perforation and cholecystitis. The patient was moved to the surgical service for an emergency operation. On the resected specimen, there was a broad longitudinal ulcer at the mesenteric side. The mucosa of the gallbladder was nodular and granular, and the wall was thickened.The surface epithelium of the gallbladder was partially eroded and pyloric gland metaplasia was observed focally. Rokitansky-Aschoff sinuses were also present.From the lamina propria to the subserosal layer, there were several well-formed epithelioid cell granulomas,which were the non-caseating sarcoidal type different from the foreign-body and xanthomatous granulomas.Periodic-acid Schiff and acid fast stains revealed no organism within the granulomas. Lymphoid aggregates were present throughout the gallbladder wall. Sections from the resected ileum showed typical features of the Crohn's disease. When cholecystectomy is performed in a patient with Crohn's disease, the possibility of gallbladder involvement should be carefully examined by histopathological tests.

  5. Is the rare biosphere real or a technical artifact? A case study involving a multi-year deep subsurface time series

    Science.gov (United States)

    Magnabosco, C.; Lau, M.; Lindsay, M. R.; Alleva, R.; Stepanauskas, R.; Shivambu, S.; Maphanga, S.; van Heerden, E.; Onstott, T. C.

    2014-12-01

    The question of "who" is present in extreme environments is one of the major questions surrounding geobiological research. Techniques such as high-throughput sequencing and single cell genomics are illuminating previously unseen organisms that exist in low abundance. Commonly referred to as the "rare biosphere", the contribution of these low abundance organisms and the effect that they have on traditional diversity estimates is poorly understood. Here, we present a study that critically examines the effect that sequencing depth has on the Chao1 alpha diversity estimator and the Sørensen similarity index. This is achieved through (1) a theoretical analysis of simulated community distributions and (2) a comparison between subsurface Sanger-sequenced clone libraries and high-throughput amplicon sequences generated from a 1.3 km deep fracture (Be326_Bh2). The screening of single cells, metagenomics, and metatranscriptomics are then used to assess the authenticity and contribution of rare members identified in the deeply sequenced amplicon datasets of Be326_Bh2. In particular, a "rare" (<1% relative abundance in 16S rDNA V6 amplicon libraries) member of Ignavibacteria that has been identified and sequenced through single cell genomics is molecularly tracked over the course of a 3-year sampling campaign in Be326_Bh2 while other "rare" members prove to be merely sequencing artifacts. Ultimately, these results help us better understand the limitations of methods used to calculate diversity in long-tail environments like the terrestrial deep subsurface and the role that the rare biosphere plays in Be326_Bh2.

  6. Vertebral Angiosarcoma. Case Study.

    Science.gov (United States)

    Guzik, Grzegorz

    2015-01-01

    Bone angiosarcomas, especially vertebral angiosarcomas, are very rare. There are no studies based on large clinical samples in the literature, and only a few single case reports can be found. The symptoms of the disease are not specific. It is usually detected incidentally or at a late stage when pathological vertebral fractures or neurological complications occur. Diagnostic imaging and history help to recognize the tumour behind the symptoms, but do not allow accurate clinical diagnosis. The basis for a diagnosis is the histopathological examination supported by immunohistochemistry (IHC) assays. The case of a 26-year-old woman with an angiosarcoma involving the eighth thoracic vertebra we report reflects diagnostic problems adversely affecting the efficacy and accuracy of treatment offered to patients. The patient underwent three surgeries of the spine, including two biopsies. A needle biopsy did not provide sufficient information for the diagnosis. An open excisional biopsy, which at the same time temporarily reduced neurological deficits in the patient, was the only chance to obtain an accurate diagnosis. The third surgery was posterior decompression of the spinal cord due to the rapidly escalating paraparesis. It was not until 8 weeks later that the final diagnosis was established. At that time, the patient could not be qualified for any supplementary treatment. The patient died in hospital 6 months after the onset of disease. PMID:26468177

  7. [Congenital toxoplasmosis with ocular involvment--case report].

    Science.gov (United States)

    Constantin, Farah; Denislam, Dogan

    2014-01-01

    Two thirds of the congenital toxoplasmosis cases describe minimal or inapparent symptoms present at birth, being diagnosed from a psychomotor retard. The forms of chorioretinitis may be described by repeated outbursts in the first years of life. Chorioretinitis or focal necrotizing retinitis usually develops in a bilateral way, being progressive and leading to blindness. Usually there is only one focal inflammatory beginning at the edge of a pigmented scar and the local inflammatory process may extend through successive spikes in other regions of the retina. Active chorioretinitis is expressed clinically by a blurred misty eyesight, with the advent of scotomas, photophobia, and if the macula is involved, the loss of the central eyesight may occur. In this paper I present the patient R.A., 6 years old from Constanta who is hospitalized in the Clinic of Infectious Diseases for investigations and treatment continuity because positive IgG Toxoplasma was previously found. The child has spastic quadriplegia and profound mental retardation.

  8. Xanthoma disseminatum: A progressive case with multisystem involvement

    Directory of Open Access Journals (Sweden)

    A M Attia

    2014-01-01

    Full Text Available Xanthoma disseminatum (XD is a rare, benign, non-Langerhans cell histiocytic disorder. The pathogenesis is not clear. It manifests with multiple, grouped, red-brown to yellow papules and nodules involving the skin, mucous membranes, and internal organs. We present a case of progressive XD in a 10-year-old male child. The patient presented with progressive, bilateral and symmetrical, reddish-brown, coalescent papules on the neck, around both eyes and all over his trunk and extremities. Skin lesions were accompanied by blurred vision and hoarseness of voice. Examination revealed xanthomatous infiltration of cornea, oral, pharyngeal, and laryngeal mucosae. The patient had diabetes insipidus that was diagnosed 2 years before the appearance of skin lesions. Medical treatment with corticosteroids (20 mg/day and azathioprine (2 mg/kg/day did not stop the disease progression.

  9. [A case report of pleural involvement in primary macroglobulinemia].

    Science.gov (United States)

    Noguchi, M; Yamaguchi, A; Tsuboi, E; Watanabe, T; Narui, K; Yoshimura, K; Chonabayashi, N; Nakata, K; Kanbayashi, H; Endo, Y

    1990-01-01

    A case of primary macroglobulinemia with pleural and gastric involvement was presented. A 48-year-old female was admitted with productive cough. On physical examination neither lymphoadenopathy nor hepatosplenomegaly were found. In addition, no bleeding tendency nor disturbance of the visual acuity were detected. Her chest roentgenogram showed a moderate amount of pleural effusion in the left pleural cavity without infiltration in the lung fields and no evidence of swollen hilar or mediastinal lymphnodes. A monoclonal M-band of to IgM-kappa type was observed in her serum and the pleural effusion. The diffuse ulcerative lesion in the gastric mucosa was detected by gastrofiberscopy. The lymphoid cells taken from the pleural effusion and the gastric mucosa stained positively with fluorescein-conjugated antiserum to u or the kappa chain. Pleural effusion and gastric infiltration of lymphoid cells improved remarkably following ACOP therapy. PMID:2113145

  10. Brucellosis with cervical vertebrae and pulmonary involvement: A rare case

    Directory of Open Access Journals (Sweden)

    Gül Karagöz

    2015-12-01

    Full Text Available The spine is the most common site of musculoskeletal involvement of brucellosis. However, there is no case report presented in the literature of both cervical vertebrae spondylodiscitis and pulmonary involvement of brucella.We reported a 52-year-old woman complaining for one month of fever with rigors, fatigue, malaise, pain on the neck and arm, and sweating. The Wright agglutination test for brucella was positive at titers of 1/640. MRI of the cervical vertebrae was consistent with spondylodiscitis and paravertebral and epidural abscesses. Ground glass opacity was seen in the left upper lobe on CT scanning of the chest. Percutaneous image-guided biopsy was performed and Brucella melitensis was isolated. The patient was treated with streptomycin for 3 weeks, plus doxycycline and rifampicin for 3 months. We recommend tissue culture for rucella patients with lung lesions. Isolation of the microorganism from a biopsy material provides conclusive evidence. J Microbiol Infect Dis 2015;5(4: 173-175

  11. Nerve and muscle involvement in mitochondrial disorders: an electrophysiological study.

    Science.gov (United States)

    Mancuso, Michelangelo; Piazza, Selina; Volpi, Leda; Orsucci, Daniele; Calsolaro, Valeria; Caldarazzo Ienco, Elena; Carlesi, Cecilia; Rocchi, Anna; Petrozzi, Lucia; Calabrese, Rosanna; Siciliano, Gabriele

    2012-04-01

    Involvement of the peripheral nervous system in mitochondrial disorders (MD) has been previously reported. However, the exact prevalence of peripheral neuropathy and/or myopathy in MD is still unclear. In order to evaluate the prevalence of neuropathy and myopathy in MD, we performed sensory and motor nerve conduction studies (NCS) and concentric needle electromyography (EMG) in 44 unselected MD patients. NCS were abnormal in 36.4% of cases, and were consistent with a sensori-motor axonal multineuropathy (multifocal neuropathy), mainly affecting the lower limbs. EMG evidence of myopathy was present in 54.5% of patients, again mainly affecting the lower limbs. Nerve and muscle involvement was frequently subclinical. Peripheral nerve and muscle involvement is common in MD patients. Our study supports the variability of the clinical expression of MD. Further studies are needed to better understand the molecular basis underlying the phenotypic variability among MD patients. PMID:21751099

  12. The toxicology and comorbidities of fatal cases involving quetiapine.

    Science.gov (United States)

    Pilgrim, Jennifer L; Drummer, Olaf H

    2013-06-01

    The use of quetiapine in Australia has increased rapidly in recent years. Anecdotal and post-marketing surveillance reports indicate an increase in quetiapine misuse in prisons as well as an increase in its availability on the black-market. This study examined a cohort of quetiapine-associated deaths occurring in Victoria, Australia, between 2001 and 2009, to determine the prevalence of deaths associated with this drug and to determine whether misuse represents a legitimate concern. Case details were extracted from the National Coronial Information System. There were 224 cases with an average age of 43 years of age (range 15-87 years). The cause of death was mostly drug toxicity (n = 114, 51 %), followed by natural disease (n = 60, 27 %), external injury (n = 31, 14 %) and unascertained causes (n = 19, 8 %). Depression and/or anxiety were common, observed in over a third of the cohort (80 cases, 36 %). About 20 % of cases did not mention a psychiatric diagnosis at all which raises the question of whether quetiapine had been prescribed correctly in these cases. Cardiovascular disease was the most commonly reported illness after mental disease. Quetiapine ranged in concentration from the limit of reporting (0.01 mg/L) to 110 mg/L. The median concentration of quetiapine was much lower in the natural disease deaths (0.25 mg/L) compared with drug caused deaths (0.7 mg/L). The most commonly co-administered drug was diazepam in 81 (36 %) cases. There were a small number of cases where quetiapine contributed to a death where it had not apparently been prescribed, including the death of a 15 year old boy and one of a 34 year old female. Overall, misuse of quetiapine did not appear to be a significant issue in this cohort; use of the drug only occasionally led to fatalities when used in excess or concomitantly with interacting drugs. However, considering that it is a recent social concern, it is possible that analysis of cases post 2009 would reveal

  13. Collision studies involving C60 (Buckminsterfullerene) ions

    International Nuclear Information System (INIS)

    The discovery of the exceptional stability of C60 (Buckminsterfullerene) and its ions has prompted a large number of experimental and theoretical investigations concerning this soccerball-shaped molecule. After the discovery of a method, by which macroscopic quantities of C60 are available, this molecule has become an obvious candidate for structural and dynamic investigations by atomic-collision experiments. In our experiments, the fragment distributions suggest a mechanism where fragmentation occurs by sequential loss of 'pairs' of carbon atoms. We have continued the C+60 fragmentation studies and also included negative and multiply charged as well as other fullerene ions besides C60. In the case of positive fullerenes, only even-numbered molecules were observed, but for the negative fullerenes, also odd-numbered molecules were recorded on the ∼ 0.5% level relative to the even-numbered components. This finding indicates that the electron structure also plays an important role for the stability of fullerene ions, or perhaps that negative molecules can exist in some isomeric form. The total destruction cross sections for fullerene ions have been measured in several target gases. We are planning to continue with collisional studies of various fullerene ions with special emphasis on a better understanding of the collisionally induced fragmentation for ions in well prepared states, and also endohedral complexes and fusion will be investigated in collision studies. (EG) (8 refs.)

  14. New high-order, semi-implicit Hybridized Discontinuous Galerkin - Spectral Element Method (HDG-SEM) for simulation of complex wave propagation involving coupling between seismic, hydro-acoustic and infrasonic waves: numerical analysis and case studies.

    Science.gov (United States)

    Terrana, S.; Vilotte, J. P.; Guillot, L.

    2015-12-01

    New seismological monitoring networks combine broadband seismic receivers, hydrophones and micro-barometers antenna, providing complementary observation of source-radiated waves. Exploiting these observations requires accurate and multi-media - elastic, hydro-acoustic, infrasound - wave simulation methods, in order to improve our physical understanding of energy exchanges at material interfaces.We present here a new development of a high-order Hybridized Discontinuous Galerkin (HDG) method, for the simulation of coupled seismic and acoustic wave propagation, within a unified framework ([1],[2]) allowing for continuous and discontinuous Spectral Element Methods (SEM) to be used in the same simulation, with conforming and non-conforming meshes. The HDG-SEM approximation leads to differential - algebraic equations, which can be solved implicitly using energy-preserving time-schemes.The proposed HDG-SEM is computationally attractive, when compared with classical Discontinuous Galerkin methods, involving only the approximation of the single-valued traces of the velocity field along the element interfaces as globally coupled unknowns. The formulation is based on a variational approximation of the physical fluxes, which are shown to be the explicit solution of an exact Riemann problem at each element boundaries. This leads to a highly parallel and efficient unstructured and high-order accurate method, which can be space-and-time adaptive.A numerical study of the accuracy and convergence of the HDG-SEM is performed through a number of case studies involving elastic-acoustic (infrasound) coupling with geometries of increasing complexity. Finally, the performance of the method is illustrated through realistic case studies involving ground wave propagation associated to topography effects.In conclusion, we outline some on-going extensions of the method.References:[1] Cockburn, B., Gopalakrishnan, J., Lazarov, R., Unified hybridization of discontinuous Galerkin, mixed and

  15. 21q21 deletion involving NCAM2: report of 3 cases with neurodevelopmental disorders.

    Science.gov (United States)

    Petit, Florence; Plessis, Ghislaine; Decamp, Matthieu; Cuisset, Jean-Marie; Blyth, Moira; Pendlebury, Maria; Andrieux, Joris

    2015-01-01

    Here we report three patients affected with neurodevelopmental disorders and harbouring 21q21 deletions involving NCAM2 gene. NCAM (Neural Cell Adhesion Molecule) proteins are involved in axonal migration, synaptic formation and plasticity. Poor axonal growth and fasciculation is observed in animal models deficient for NCAM2. Moreover, this gene has been proposed as a candidate for autism, based on genome-wide association studies. In this report, we provide a comprehensive molecular and phenotypical characterisation of three deletion cases giving additional clues for the involvement of NCAM2 in neurodevelopment.

  16. Dengue encephalitis with predominant cerebellar involvement: Report of eight cases with MR and CT imaging features

    International Nuclear Information System (INIS)

    CNS dengue infection is a rare condition and the pattern of brain involvement has not been well described. We report the MR imaging (MRI) features in eight cases of dengue encephalitis. We retrospectively searched cases of dengue encephalitis in which imaging was performed. Eight cases (three men, five women; age range: 8-42 years) diagnosed with dengue encephalitis were included in the study. MR studies were performed on 3-T and 1.5-T MR clinical systems. Two neuroradiologists retrospectively reviewed the MR images and analysed the type of lesions, as well as their distribution and imaging features. All eight cases exhibited MRI abnormalities and the cerebellum was involved in all cases. In addition, MRI signal changes were also noted in the brainstem, thalamus, basal ganglia, internal capsule, insula, mesial temporal lobe, and cortical and cerebral white matter. Areas of susceptibility, diffusion restriction, and patchy post-contrast enhancement were the salient imaging features in our cohort of cases. A pattern of symmetrical cerebellar involvement and presence of microbleeds/haemorrhage may serve as a useful imaging marker and may help in the diagnosis of dengue encephalitis. (orig.)

  17. Dengue encephalitis with predominant cerebellar involvement: Report of eight cases with MR and CT imaging features

    Energy Technology Data Exchange (ETDEWEB)

    Hegde, Vinay; Bhat, Maya; Prasad, Chandrajit; Gupta, A.K.; Saini, Jitender [National Institute of Mental Health and Neurosciences, Department of Neuroimaging and Interventional Radiology, Bangalore, Karnataka (India); Aziz, Zarina [Sri Sathya Sai Institute of Medical Science, Department of Radiology, Bangalore (India); Kumar, Sharath [Apollo Hospital, Department of Neuroradiology, Bangalore (India); Netravathi, M. [National Institute of Mental Health and Neurosciences, Department of Neurology, Bangalore (India)

    2014-11-01

    CNS dengue infection is a rare condition and the pattern of brain involvement has not been well described. We report the MR imaging (MRI) features in eight cases of dengue encephalitis. We retrospectively searched cases of dengue encephalitis in which imaging was performed. Eight cases (three men, five women; age range: 8-42 years) diagnosed with dengue encephalitis were included in the study. MR studies were performed on 3-T and 1.5-T MR clinical systems. Two neuroradiologists retrospectively reviewed the MR images and analysed the type of lesions, as well as their distribution and imaging features. All eight cases exhibited MRI abnormalities and the cerebellum was involved in all cases. In addition, MRI signal changes were also noted in the brainstem, thalamus, basal ganglia, internal capsule, insula, mesial temporal lobe, and cortical and cerebral white matter. Areas of susceptibility, diffusion restriction, and patchy post-contrast enhancement were the salient imaging features in our cohort of cases. A pattern of symmetrical cerebellar involvement and presence of microbleeds/haemorrhage may serve as a useful imaging marker and may help in the diagnosis of dengue encephalitis. (orig.)

  18. Case report 449: Chondroblastoma involving C5 and C6

    Energy Technology Data Exchange (ETDEWEB)

    Howe, J.W.; Yochum, T.R.; Sladich, M.A.; Baumgard, S.

    1988-01-01

    A case of chondroblastoma of the cervical spine is presented in a sixteen year old male. Both the axial location and the presence of an associated soft tissue mass make this an unusual case. Treatment is briefly considered. (orig.)

  19. Early Stakeholder Involvement in the Project Definition Phase: Case Renovation

    OpenAIRE

    Aki Aapaoja; Harri Haapasalo; Pia Söderström

    2013-01-01

    Relational project delivery methods (RPDMs) have been widely offered as a solution to increasing holistic project value creation. Furthermore, early stakeholder involvement has been emphasized as one of the cornerstones of RPDM. The purpose of this paper is to examine who the stakeholders are that should be involved early in the project definition phase. This paper discusses the process and nature of the project definition phase in RPDM, with the main focus on early stakeholder involvement. T...

  20. Cytodiagnosis of multiple myeloma presenting as orbital involvement: a case report

    Directory of Open Access Journals (Sweden)

    Sharma Alok

    2006-01-01

    Full Text Available Abstract Background Plasma cell neoplasms represent autonomous proliferations of plasma cells and can manifest as diffuse myeloma with systemic involvement (plasma cell myeloma or multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS, or as variants of plasma cell myeloma such as indolent myeloma, smoldering myeloma, osteosclerotic myeloma, plasma cell leukaemia and non-secretory myeloma. Localized neoplastic proliferation of plasma cells presents as solitary plasmacytoma of bone or extramedullary plasmacytoma. Involvement of orbit can occur as a solitary plasmacytoma, or as part of systemic involvement in multiple myeloma, the clinical outcome being significantly worse in the latter setting. Orbital involvement in multiple myeloma is very rare with less than 50 cases reported in the literature. Early cytological diagnosis of such lesions is vital for timely institution of appropriate therapy. As far as we are aware only six previous cases of cytological diagnosis of multiple myeloma involving the orbit are on record. Case presentation A 37 year old male presented with low grade fever showing evening rise, headache, diplopia and swelling in the right periorbital and temporal region. Imaging studies revealed destructive lesion of sphenoid, frontal bone and zygomatic arch with soft tissue component extending to infratemporal fossa and orbit. A fine needle aspirate from the temporal region swelling showed features of a plasmacytoma, and subsequent workup confirmed the presence of systemic disease. A final diagnosis of multiple myeloma with orbital involvement at presentation was made. Conclusion Present case describes the extremely rare presentation of multiple myeloma with orbital involvement and highlights the utility of cytology in such lesions. Fine needle aspiration diagnosis of plasmacytoma at extramedullary sites offers an opportunity for non-invasive verification of systemic involvement, and thus plays a major role in

  1. Associative visual agnosia: a case study.

    Science.gov (United States)

    Charnallet, A; Carbonnel, S; David, D; Moreaud, O

    2008-01-01

    We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study, an alternative account in the framework of (non abstractive) episodic models of memory.

  2. The Effects of Student Involvement and College Environment on Students' Learning and Living Experience at World-Class Research Universities in China: A Comparative Case Study of the University of Hong Kong (HKU) and Shanghai Jiao Tong University (SJTU)

    Science.gov (United States)

    Chan, Roy Yew-Hung

    2011-01-01

    This comparative research examined the effects of student involvement and college environment on students' learning and living experience delivered by two aspiring world-class universities in Hong Kong and Shanghai. Few studies have shown how the levels of student involvement and college environment can benefit students at world-class institution.…

  3. Grip strength measurements at two different wrist extension positions in chronic lateral epicondylitis-comparison of involved vs. uninvolved side in athletes and non athletes: a case-control study

    Directory of Open Access Journals (Sweden)

    Bhargava Arti S

    2010-09-01

    Full Text Available Abstract Background Lateral epicondylitis is a common sports injury of the elbow caused due to altered muscle activation during repetitive wrist extension in many athletic and non-athletic endeavours. The amount of muscle activity and timing of contraction eventually is directly dependent upon joint position during the activity. The purpose of our study was to compare the grip strength in athletes with lateral epicondylalgia in two different wrist extension positions and compare them between involved and uninvolved sides of athletes and non-athletes. Methods An assessor-blinded case-control study of eight athletes and twenty-two non-athletes was done. The grip strength was measured using JAMAR® hand dynamometer in kilograms-force at 15 degrees (slightly extended and 35 degrees (moderately extended wrist extension positions (maintained by wrist splints on both involved and uninvolved sides of athletes and non-athletes with unilateral lateral epicondylitis of atleast 3 months duration. Their pain was to be elicited with local tenderness and two of three tests being positive- Cozen's, Mill's manoeuvre, resisted middle finger extension tests. For comparisons of grip strength, Wilcoxon signed rank test was used for within-group comparison (between 15 and 35 degrees wrist extension positions and Mann-Whitney U test was used for between-group (athletes vs. non-athletes comparisons at 95% confidence interval and were done using SPSS 11.5 for Windows. Results Statistically significant greater grip strength was found in 15 degrees (27.75 ± 4.2 kgms in athletes; 16.45 ± 4.2 kgms in non-athletes wrist extension than at 35 degrees (25.25 ± 3.53 kgm in athletes and 14.18 ± 3.53 kgm in non-athletes. The athletes had greater grip strength than non-athletes in each of test positions (11.3 kgm at 15 degrees and 11.07 kgm at 35 degrees measured. There was also a significant difference between involved and uninvolved sides' grip strength at both wrist

  4. Multi - Case study on the organizational driving behaviors involving informatization in large -sized companies%大型企业信息化进程组织推动的多案例研究

    Institute of Scientific and Technical Information of China (English)

    王志刚

    2011-01-01

    本文通过多案例研究,总结归纳了企业信息化发展的组织推动行为,完成了企业信息化组织推动工作主体的组织结构分析,研究归纳出企业内部推动信息化的四类主体:高层领导、业务部门、管理部门、信息化部门,构建了大型企业信息化进程的组织推动框架模型.%Through a multi - case study, the organizational driving behaviors for the development of informatization in large-sized companies are investigated.The organizational structures for related tasks are analyzed and four types of entities are identified as the internal driving forces for the development of informatization, they are top management, business units, administration departments, and IT department.Consequently, a comprehensive framework for understanding the organizational driving behaviors involving informatization in large -sized companies is postulated.

  5. Darier disease with oral and esophageal involvement: A case report

    Directory of Open Access Journals (Sweden)

    Magesh Karuppur Thiagarajan

    2011-01-01

    Full Text Available A 58-year-old man presented with itchy papular eruptions all over the body since 15 years. Intraoral examination revealed raised papular lesions on the labial mucosa, hard palate, and tongue. The histopathology of the oral and skin lesions was confirmative of Darier disease (DD. This patient also showed esophageal involvement, which was confirmed histopathologically. Such a presentation of DD, with oral and esophageal involvement, is rare.

  6. Objectivist case study research

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Fachner, Jörg

    2016-01-01

    be achieved through the use of objectivist case study research. The strength of the case study design is that it allows for uncovering or suggesting causal relationships in real-life settings through an intensive and rich collection of data. According to Hilliard (1993), the opposite applies for extensive......In order to comprehend the impact of music therapy or music therapy processes, a researcher might look for an approach where the topic under investigation can be understood within a broader context. This calls for a rich inclusion of data and consequently a limited number of participants and may...... designs, in which a small amount of data is gathered on a large number of subjects. With the richness of data, the intensive design is ―the primary pragmatic reason for engaging in single-case or small N research‖ (p. 374) and for working from an idiographic rather than a nomothetic perspective....

  7. A COMPARATIVE STUDY OF PRODUCT INVOLVEMENT IN GUJARAT

    OpenAIRE

    Sandhe, Dr. Ashutosh

    2015-01-01

    The concept of product involvement is a relatively new concept. However, in recent times, lot of research has been carried out in this area. Marketers are trying to study buyer behavior based on their involvement with a product or service. In this research also, two contrasting product were selected representing two extreme levels of product involvement. A residential house which is a high involvement product and a toothpaste which is a low involvement product. Product involvement was fo...

  8. : Case studies: France

    OpenAIRE

    Bonerandi, Emmanuelle; Santamaria, Frédéric

    2005-01-01

    Case studies on territorial governance : urban region of Lyon (France) and the "Pays" policy (France) in the framework of the ESPON 2.3.2 project Études de cas sur la gouvernance territoriale : région urbaine de Lyon et politique des pays

  9. Renal involvement in childhood lupus: A study from Kolkata, India

    Directory of Open Access Journals (Sweden)

    Madhumita Nandi

    2012-01-01

    Full Text Available Systemic lupus erythematosus (SLE is a multi-system disease of autoimmune origin. The relative incidences of the various manifestations in children with SLE are significantly different from adults and among different age-groups of children. To analyze the characteristics of childhood lupus nephritis (LN, we prospectively followed-up 23 cases of pediatric LN, diag-nosed over a period of five years, in the pediatric rheumatology clinic at the Institute of Post Graduate Medical Education and Research, Kolkata, India. The resultant database was analyzed using standard statistical methods. Of all childhood lupus cases treated in our clinic over the last five years (n = 42, 54.7% (n = 23 had renal involvement. This study has tried to delineate the disease trends of childhood lupus from Eastern India. Certain important trends have emerged that are different from other contemporary Indian and International observations.

  10. A Rare Case: Gastric Cancer; Involving Primery Thoracal Vertebral Metastases

    Directory of Open Access Journals (Sweden)

    Harun Arslan

    2013-06-01

    Full Text Available Primery bone metastases rarely occur in gastric cancer. Bone metastases indicate that the prognosis is bad. In that article we present a case that is diagnosed as a gastric cancer with primary bone metasteses that caused pathologic thoracal vertebral fracture seenby computer ised tomography.

  11. First Case of Lyme Arthritis Involving a Prosthetic Knee Joint

    Science.gov (United States)

    Wright, William F.; Oliverio, James A.

    2016-01-01

    Borrelia burgdorferi sensu stricto is the most common tick-borne illness in the United States. Arthritis is usually a mani­festation of late dis­ease but has not been associated with cases of periprosthetic joint infections. We report on a patient who was first diagnosed with periprosthetic joint infection and subsequently Lyme arthritis. PMID:27419168

  12. A Rare Case: Gastric Cancer; Involving Primery Thoracal Vertebral Metastases

    OpenAIRE

    Harun Arslan

    2013-01-01

    Primery bone metastases rarely occur in gastric cancer. Bone metastases indicate that the prognosis is bad. In that article we present a case that is diagnosed as a gastric cancer with primary bone metasteses that caused pathologic thoracal vertebral fracture seenby computer ised tomography.

  13. Cardiac involvement in Emery Dreifuss muscular dystrophy: a case series

    OpenAIRE

    Buckley, A.; Dean, J.; Mahy, I

    1999-01-01

    Three patients with Emery Dreifuss muscular dystrophy are reported. Emery Dreifuss muscular dystrophy is an X linked muscular dystrophy, in which locomotor involvement is characteristically mild and slowly progressive. The effect on the heart becomes apparent in the teenage years and is characterised by cardiac conduction defects and infiltration of the myocardium by fibrous and adipose tissue. It first affects the atria, which results in atrial paralysis; treatment with ventricular pacing is...

  14. A Case of Paget’s Disease with Scapula Involvement

    Directory of Open Access Journals (Sweden)

    Nilgün Mesci

    2015-12-01

    Full Text Available Paget’s disease is a common bone disorder which is characterized by excessive bone turnover. This condition rarely involves sternum, patella, scapula, hand, foot and facial bones. A 65-year-old male patient was admitted to our outpatient clinic with the complaint of right-sided pain that radiated from his groin to his knee for the last 5-6 years. His physical examination revealed limited hip movements and pain. Whole body bone scintigraphy detected diffuse, increased activity in the right coxa and entire scapula. Elevated alkaline phosphatase (ALP (367 U/L was observed in laboratory results. Further investigations and examinations were performed in order to exclude possible malignancies (eg. prostate, lung due to involvement of scapula which is atypical for Paget’s disease. Finally, poliostotic Paget’s disease with pelvic and scapular involvement was considered as the definite diagnosis. Treatment with risedronate sodium was started at a dose of 35 mg daily which led to marked improvement in hip pain and reduction in ALP level to 150 U/L after one month. While making a differential diagnosis of scintigraphic lesions at an unusual location such as scapula, consideration should be given to the fact that Paget’s disease may affect any bone in the body although this is rare

  15. Early user involvement and participation in employee self-service application deployment: theory and evidence from four Dutch governmental cases.

    NARCIS (Netherlands)

    Koopman, G.; Batenburg, R.

    2009-01-01

    This paper theoretically and empirically addresses the notion that user participation and involvement is one of the important factors for IS success. Different models and studies are reviewed to define and classify types of early end-user involvement and participation. Next, five case studies are p

  16. Corporate Governance. Case Studies

    OpenAIRE

    Manuel, Eduardo

    2007-01-01

    This paper pretends to do a theoretical approach of Corporate Governance, having as support some case studies about companies like Coca-Cola, Nokia, Microsoft, and Amazon.com. The methodology adopted for this work is based in information from these companies available in their websites and annual reports. I concluded that both companies show the corporate governance components according to their core business and their environmental business.

  17. Case study - Czechoslovakia

    International Nuclear Information System (INIS)

    In the lecture Case Study - Czechoslovakia with the sub-title 'Unified System of Personnel Preparation for Nuclear Programme in Czechoslovakia' the actual status and the current experience of NPP personnel training and preparation in Czechoslovakia are introduced. The above mentioned training system is presented and demonstrated by the story of a proxy person who is going to become shift engineer in a nuclear power plant in Czechoslovakia. (orig./HP)

  18. Case Studies - Cervical Cancer

    Centers for Disease Control (CDC) Podcasts

    2010-10-15

    Dr. Alan Waxman, a professor of obstetrics and gynecology at the University of New Mexico and chair of the American College of Obstetricians and Gynecologists (ACOG) committee for the underserved, talks about several case studies for cervical cancer screening and management.  Created: 10/15/2010 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Cancer Prevention and Control (DCPC).   Date Released: 6/9/2010.

  19. Patient Complaint Cases in Primary Health Care: What Are the Characteristics of General Practitioners Involved?

    Directory of Open Access Journals (Sweden)

    Søren Birkeland

    2013-01-01

    Full Text Available Background. Limited knowledge exists about factors increasing the risk of general practitioners becoming involved in a complaint case or getting disciplined in connection with a complaint case. Aim. The present study aimed to identify the general practitioner and practice characteristics associated with complaint cases and discipline. Methods. Information on general practitioners involved in complaint case decisions during one year (2007 was linked to Danish National register data on all general practitioners (. Logistic regression was used for statistical analysis. Results. With regard to complaints concerning daytime services (, the professional seniority of the general practitioner was positively associated with the odds of receiving a complaint decision (OR = 1.44 per 20 years of seniority; CI 95%, 1.04–1.98. Likewise, having more consultations per day was associated with increased odds (OR = 1.29 per 10 extra consultations per day; CI 95%, 1.07–1.54. No statistically significant association could be demonstrated between being disciplined and general practitioner or practice characteristics. Conclusion. The possible relationship between professional seniority, rate of consultations, and complaint cases merits further studies to clarify the impact of professional seniority and workload on professional performance and to furthermore consider the role of factors such as job content and communication styles.

  20. Candida Parapsilosis Arthritis Involving the Ankle in a Diabetes Patient: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Sung, Jin Kyeong; Chun, Kyung Ah [Dept. of Radiology, The Catholic University of Korea Uijeongbu St. Mary' s Hospital, Uijeongbu (Korea, Republic of)

    2011-06-15

    Candida parapsilosis is a rare opportunistic fungal pathogen of the musculoskeletal region. Immune function of almost all patients is severely disturbed. Most reported cases of septic arthritis of joints by Candida involve the knee, especially Candida parapsilosis. To our knowledge, there has been only one case report of Candida parapsilosis involving the ankle presented on only plain radiography. We report a case of Candida parapsilosis arthritis involving the ankle in a diabetes patient which was shown on MR imaging.

  1. A fatal case of chikungunya virus infection with liver involvement.

    Science.gov (United States)

    Chua, H H; Abdul Rashid, K; Law, W C; Hamizah, A; Chem, Y K; Khairul, A H; Chua, K B

    2010-03-01

    Recovery from chikungunya is previously considered universal and mortality due to the virus is rare and unusual. Findings from recent chikungunya outbreaks occurred in Reunion Island and India have since challenged the conventional view on the benign nature of the illness. Malaysia has experienced at least of 4 outbreaks of chikungunya since 1998. In the present on-going large outbreak due to chikungunya virus of Central/East African genotype, a previous healthy sixty six years gentleman without co-morbidity was noted to have severe systemic infection by the virus and involvement of his liver. He subsequently passed away due to cardiovascular collapse after 5 days of illness.

  2. Studies of Genes Involved in Congenital Heart Disease

    Directory of Open Access Journals (Sweden)

    Tushar K. Ghosh

    2014-05-01

    Full Text Available Congenital heart disease (CHD affects the intricate structure and function of the heart and is one of the leading causes of death in newborns. The genetic basis of CHD is beginning to emerge. Our laboratory has been engaged in identifying mutations in genes linked to CHD both in families and in sporadic cases. Over the last two decades, we have employed linkage analysis, targeted gene sequencing and genome wide association studies to identify genes involved in CHDs. Cardiac specific genes that encode transcription factors and sarcomeric proteins have been identified and linked to CHD. Functional analysis of the relevant mutant proteins has established the molecular mechanisms of CHDs in our studies.

  3. Langerhans cell histiocytosis with multisystem involvement in an infant: A case report

    Science.gov (United States)

    BI, LINTAO; SUN, BUTONG; LU, ZHENXIA; SHI, ZHANGZHEN; WANG, DAN; ZHU, ZHENXING

    2015-01-01

    Langerhans cell histiocytosis (LCH) is a proliferative disease of histiocyte-like cells, with a wide range of clinical presentations that vary from a solitary lesion to more severe multifocal or disseminated lesions. The disease can affect any age group; however, the peak incidence rate is in infants aged between 1 and 3 years-old. Diagnosis of LCH should be based on the synthetical analysis of clinical presentations, in addition to features of imaging and histopathology. Although certain cases regress spontaneously, other patients require systemic chemotherapy together with the administration of steroids. The present study reports the case of an infant with LDH with multisystem involvement, including that of the bone, skin, orbit, spleen and lungs. The patient received chemotherapy and obtained rapid improvement in the involved systems. A total of 2.5 years after completion of the therapy, the patient still remains in follow-up and no evidence of active disease has been noted. PMID:26136948

  4. Endoscopic biopsy of a B-cell lymphoma involving the entire ventricular system: A case report

    Science.gov (United States)

    QIN, JIA-ZHEN; WU, YUE-KUI; YANG, ZHI-JUN; LV, JUN; DANG, YUAN-YUAN; ZHANG, HONG-TIAN; DAI, YI-WU

    2016-01-01

    A 62-year-old male suffering from vomiting and mild preceding nausea for 15 days was examined in the present case report. Magnetic resonance imaging revealed a homogeneously enhancing cluster-like lesion involving the lateral, third and fourth ventricles. An endoscopic biopsy was performed, and histopathological examination led to the diagnosis of a high-grade diffuse large B-cell lymphoma. To the best of our knowledge, the present study reports the first case of a primary lymphoma involving the entire ventricular system. Therefore, primary lymphomas should be considered in the list of ventricular tumors. An endoscopic biopsy requires minimal invasion to obtain an adequate tissue sample, and frequently leads to the correct diagnosis and subsequent treatment protocols. PMID:26889262

  5. A case of breast cancer involving a ventriculoperitoneal shunt.

    Science.gov (United States)

    Kamei, Mirei; Kikuchi, Nobuyuki; Ichimura, Homare; Chujo, Masao; Takahashi, Yoshiaki; Sugio, Kenji

    2016-12-01

    An 84-year-old woman was examined for an enlargement of an induration in the left breast. A ventriculoperitoneal shunt had been placed for postoperative normal pressure hydrocephalus of a cerebral hemorrhage, and it had penetrated the mass according to the computed tomography findings. Breast cancer was diagnosed after a close examination; however, close observation was selected because her family rejected treatment. She developed somnolence 7 months after the initial examination, and ventricular dilatation and expansion of the low-density region around the ventricle were noted on computed tomography, suggesting that the enlarged tumor had excluded the shunt and caused obstruction. The growth of breast carcinoma involving a shunt tube can be the cause of obstruction of a ventriculoperitoneal shunt. Our findings suggest that a breast lesion should be evaluated at both pre- and postoperation. PMID:26943684

  6. Neuroendocrine tumors involving the gastroenteropancreatic tract: a clinicopathological evaluation of 773 cases

    Directory of Open Access Journals (Sweden)

    Bruna Estrozi

    2011-01-01

    Full Text Available OBJECTIVE: Description of some of the clinical pathological characteristics of neuroendocrine tumors of the gastroenteropancreatic tract in Brazilian patients. INTRODUCTION: Neuroendocrine tumors arise in many organs and share common pathological features. In 2010, the World Health Organization published a new classification for neuroendocrine tumors using a three-tiered system that applies the terms neuroendocrine tumor Grade 1, neuroendocrine tumor Grade 2, and neuroendocrine carcinoma. The tumor grades are based on their mitotic rate and the Ki-67 index. In Brazil, information on neuroendocrine tumors of gastroenteropancreatic tract is scarce. METHODS: This study investigated clinicopathological features of 773 Brazilian gastroenteropancreatic neuroendocrine tumor cases from all the geographic regions of Brazil. All of the cases emerged from the files of a single institution (a large pathology reference laboratory between 1997 and 2009. In addition, the gastroenteropancreatic neuroendocrine tumors were graded according to the new 2010 World Health Organization classification. RESULTS: Overall there were a higher number of neuroendocrine tumors in female over male. The lower ages were seen in patients with appendiceal tumors. The most common anatomic location involved was stomach followed by small and large intestines. All cases involving the appendix were of grade 1 and 92.1% of the neuroendocrine tumors of the esophagus were neuroendocrine carcinomas (grade 3. CONCLUSIONS: In this series, the proportion of NET cases in the total number of surgical pathology cases at our institution over the past 12 years is increasing.

  7. NOx trade. Case studies

    International Nuclear Information System (INIS)

    Some of the questions with respect to the trade of nitrogen oxides that businesses in the Netherlands have to deal with are dealt with: should a business buy or sell rights for NOx emission; which measures must be taken to reduce NOx emission; how much must be invested; and how to deal with uncertainties with regard to prices. Simulations were carried out with the MOSES model to find the answers to those questions. Results of some case studies are presented, focusing on the chemical sector in the Netherlands. Finally, the financial (dis)advantages of NOx trade and the related uncertainties for a single enterprise are discussed

  8. A case for increased private sector involvement in Ireland's national animal health services.

    Science.gov (United States)

    More, Simon J

    2008-01-01

    Non-regulatory animal health issues, such as Johne's disease, infectious bovine rhinotracheitis (IBR) and mastitis will become increasing important, with ongoing globalisation of markets in animals and animal products. In response, Ireland may need to broaden the scope of its national animal health services. However, there have been concerns about the respective roles and responsibilities (both financial and otherwise) of government and industry in any such moves. This paper argues the case for increased private sector involvement in Ireland's national animal health services, based both on theoretical considerations and country case studies (the Netherlands and Australia). The Dutch and Australian case studies present examples of successful partnerships between government and industry, including systems and processes to address non-regulatory animal health issues. In each case, the roles and responsibilities of government are clear, as are the principles underpinning government involvement. Furthermore, the roles and responsibilities (financial and otherwise) of the Dutch and Australian industry are determined through enabling legislation, providing both legitimacy and accountability. There are constraints on the use of EU and national government funds to support non-regulatory animal health services in EU member states (such as Ireland and the Netherlands). PMID:21851708

  9. A case for increased private sector involvement in ireland's national animal health services

    Directory of Open Access Journals (Sweden)

    More Simon J

    2008-02-01

    Full Text Available Abstract Non-regulatory animal health issues, such as Johne's disease, infectious bovine rhinotracheitis (IBR and mastitis will become increasing important, with ongoing globalisation of markets in animals and animal products. In response, Ireland may need to broaden the scope of its national animal health services. However, there have been concerns about the respective roles and responsibilities (both financial and otherwise of government and industry in any such moves. This paper argues the case for increased private sector involvement in Ireland's national animal health services, based both on theoretical considerations and country case studies (the Netherlands and Australia. The Dutch and Australian case studies present examples of successful partnerships between government and industry, including systems and processes to address non-regulatory animal health issues. In each case, the roles and responsibilities of government are clear, as are the principles underpinning government involvement. Furthermore, the roles and responsibilities (financial and otherwise of the Dutch and Australian industry are determined through enabling legislation, providing both legitimacy and accountability. There are constraints on the use of EU and national government funds to support non-regulatory animal health services in EU member states (such as Ireland and the Netherlands.

  10. [A case of myokymia-hyperhidrosis syndrome with muscle involvement].

    Science.gov (United States)

    Ono, S; Tomono, H; Maeda, Y; Shimizu, N; Shimizu, N

    1989-01-01

    The present report deals with an unique case of myokymia-hyperhidrosis syndrome. A 46-year-old man developed generalized relatively slow, undulating movement of the muscles, excessive sweating, muscle cramps and easy fatigability since three years ago. On admission, he had generalized myokymia, abnormal movements consisting of slow, undulating and worm-like muscular contractions. There was no muscle atrophy or weakness, or sensory deficits. Deep tendon reflexes were diminished and no Babinski sign or other pathological reflexes were present. Muscle tone was in normal range. Neither fasciculation nor myotonia was found. Laboratory examinations revealed elevation of BMR with normal thyroid function. The value of anti-Ach receptor antibody was below 0.6nmol/l. EMG recordings showed (1) continuous spontaneous repetitive discharges of NMU at a frequency of 30-50Hz, with duration of 1-2 seconds and amplitude of about 1 mV, were demonstrated at rest and the findings were consistent with myokymia, (2) waxing phenomenon was observed on repetitive peripheral nerve stimuli, which didn't improve by the tension test, and (3) high amplitude, long duration and polyphasic NMU, a sign of denervation, were observed on voluntary contraction. Muscle biopsy specimens from the left quadriceps showed a number of internal nuclei. On electron microscopy, clustered mitochondria and filamentous bodies were very often found in subsarcolemma. From these observations, damage to peripheral nerves, neuromuscular junctions and muscles may be responsible for the generalized myokymia in our patient. PMID:2743686

  11. Infected Thyroglossal Duct Cyst Involving Submandibular Region: A Case Report

    Directory of Open Access Journals (Sweden)

    Rahul A. Gandhi

    2011-01-01

    Full Text Available Thyroglossal duct cyst presents most frequently in the midline of the neck, either at or just below the level of the hyoid bone. They generally manifest as painless neck swelling, and they move on protrusion of tongue and during swallowing. A case of thyroglossal cyst was reported in the left submandibular region in a 14-year-old girl, above the level of hyoid bone; ultrasound examination favored a cystic lesion which moved in a vertical fashion on swallowing whereas fine needle aspiration cytology report was suggestive of simple cystic lesion of thyroglossal cyst. No lymphoid or malignant cells were present. The cyst was excised completely by surgical procedure under general anesthesia. Histopathological analysis revealed thyroglossal cyst showing columnar and flattened epithelium of cyst with focal aggregate of chronic inflammatory cells supported by fibrocollagenous cyst wall. The clinical, ultrasound, and histopathological findings suggested that the lesion was an infected thyroglossal cyst. There was no evidence of recurrence 6 months after surgery.

  12. Rosai–Dorfman disease involving gallbladder and liver—Report of a case

    Science.gov (United States)

    Arabadzhieva, Elena; Yonkov, Atanas; Bonev, Sasho; Bulanov, Dimitar; Taneva, Ivanka; Pirdopska, Tatyana; Terziev, Ivan; Dimitrova, Violeta

    2015-01-01

    Introduction Rosai–Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic disorder of unclear etiology. Lymphadenopathy commonly affects the lymph nodes of the neck and the head, but extranodal involvement has been observed too. Presentation of case We describe an unusual case of RDD with involvement of the gallbladder, liver and cystic lymph node, clinically manifested as an exacerbated cholecystitis. The patient underwent a cholecystectomy with atypical liver resection because the finding was macroscopically suspected of gallbladder cancer. The diagnosis of RDD was confirmed by immunohistochemical study. Discussion Histological features of RDD include histiocytic proliferation, emperipolesis and positive immunostaining for S-100 protein and typically negative for CD1a. Gastrointestinal localization of RDD, especially in the liver and pancreas, is extremely rare. Typically, the liver is affected as a part of systematic spread of RDD. We have not found reports for involvement of the gallbladder. Conclusion The presented case is valuable due to its rarity and difficulty in differential diagnosis. PMID:26073916

  13. Langerhans cell histiocytosis involving the liver of a male smoker: a case report

    OpenAIRE

    Savva-Bordalo Joana; Freitas-Silva Margarida

    2008-01-01

    Abstract Introduction Langerhans' cell histiocytosis is a proliferative histiocytic disorder of unknown cause originating from dendritic cells. Case presentation The authors report a case of Langerhans' cell histiocytosis in a 48-year-old man with multisystemic disease presentation, including liver involvement. Conclusion Hepatic involvement is an uncommon feature in this rare disease and there is no consensus on the most effective therapeutic approach.

  14. Associative Visual Agnosia: A Case Study

    Directory of Open Access Journals (Sweden)

    A. Charnallet

    2008-01-01

    Full Text Available We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study [1], an alternative account in the framework of (non abstractive episodic models of memory [4].

  15. CHEK2*1100delC and susceptibility to breast cancer : A collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies

    NARCIS (Netherlands)

    Easton, D; McGuffog, L; Thompson, D; Dunning, A; Tee, L; Baynes, C; Healey, C; Pharoah, P; Ponder, B; Seal, S; Barfoot, R; Sodha, N; Eeles, R; Stratton, M; Rahman, N; Peto, J; Spurdle, AB; Chen, XQ; Chenevix-Trench, G; Hopper, JL; Giles, GG; McCredie, MRE; Syrjakoski, K; Holli, K; Kallioniemi, O; Eerola, H; Vahteristo, P; Blomqvist, C; Nevanlinna, H; Kataja, Vesa; Mannermaa, A; Dork, T; Bremer, M; Devilee, P; de Bock, GH; Krol-Warmerdam, EMM; Kroese-Jansema, K; Wijers-Koster, P; Cornelisse, CJ; Tollenaar, RAEM; Meijers-Heijboer, H; Berns, E; Nagel, J; Foekens, J; Klijn, JGM; Schutte, M

    2004-01-01

    Previous studies of families with multiple cases of breast cancer have indicated that a frameshift alteration in the CHEK2 gene, 1100delC, is associated with an elevated frequency of breast cancer in such families, but the risk associated with the variant in other situations is uncertain. To evaluat

  16. Unexplained False Negative Results in Noninvasive Prenatal Testing: Two Cases Involving Trisomies 13 and 18

    Directory of Open Access Journals (Sweden)

    R. Hochstenbach

    2015-01-01

    Full Text Available Noninvasive prenatal testing (NIPT validation studies show high sensitivity and specificity for detection of trisomies 13, 18, and 21. False negative cases have rarely been reported. We describe a false negative case of trisomy 13 and another of trisomy 18 in which NIPT was commercially marketed directly to the clinician. Both cases came to our attention because a fetal anatomy scan at 20 weeks of gestation revealed multiple anomalies. Karyotyping of cultured amniocytes showed nonmosaic trisomies 13 and 18, respectively. Cytogenetic investigation of cytotrophoblast cells from multiple placental biopsies showed a low proportion of nontrisomic cells in each case, but this was considered too small for explaining the false negative NIPT result. The discordant results also could not be explained by early gestational age, elevated maternal weight, a vanishing twin, or suboptimal storage or transport of samples. The root cause of the discrepancies could, therefore, not be identified. The couples involved experienced difficulties in accepting the unexpected and late-adverse outcome of their pregnancy. We recommend that all parties involved in caring for couples who choose NIPT should collaborate to clarify false negative results in order to unravel possible biological causes and to improve the process of patient care from initial counseling to communication of the result.

  17. Liver involvement of multiple myeloma mimicking intrahepatic cholangiocarcinoma: a case report

    International Nuclear Information System (INIS)

    Nodular hepatic involvement of multiple myeloma is very rare. We report here on a case of nodular hepatic involvement of multiple myeloma that mimicked intrahepatic cholangiocarcinoma. In patients with multiple myeloma, hepatic involvement of the multiple myeloma might be included in the differential diagnosis of hepatic mass

  18. Two Case Reports on Thalamic and Basal Ganglia Involvement in Children with Dengue Fever

    Science.gov (United States)

    Adhikari, Lihini; Wijesekera, Saraji; Wijayawardena, Maheshaka; Chandrasiri, Suchithra

    2016-01-01

    There have been increasing numbers of case reports of dengue infection with unusual manifestations. Such unusual manifestations including acute liver failure and encephalopathy could be manifested even in the absence of significant plasma leakage. Further, severe organ involvement including nervous system involvement indicates severe dengue infection. However, neurological manifestations of dengue fever are rare. This is the first case report of dengue infection with thalamic and basal ganglia involvement in Sri Lanka.

  19. Two Case Reports on Thalamic and Basal Ganglia Involvement in Children with Dengue Fever

    Science.gov (United States)

    Adhikari, Lihini; Wijesekera, Saraji; Wijayawardena, Maheshaka; Chandrasiri, Suchithra

    2016-01-01

    There have been increasing numbers of case reports of dengue infection with unusual manifestations. Such unusual manifestations including acute liver failure and encephalopathy could be manifested even in the absence of significant plasma leakage. Further, severe organ involvement including nervous system involvement indicates severe dengue infection. However, neurological manifestations of dengue fever are rare. This is the first case report of dengue infection with thalamic and basal ganglia involvement in Sri Lanka. PMID:27478661

  20. Combined pulmonary involvement in hereditary lysozyme amyloidosis with associated pulmonary sarcoidosis: a case report.

    Science.gov (United States)

    McCarthy, Cormac; Deegan, Alexander P; Garvey, John F; McDonnell, Timothy J

    2013-01-01

    Sarcoidosis is a multisystem inflammatory disorder of unknown cause which can affect any organ system. Autosomal dominant lysozyme amyloidosis is a very rare form of hereditary amyloidosis. The Arg64 variant is extraordinarily rare with each family showing a particular pattern of organ involvement, however while Sicca syndrome, gastrointestinal involvement and renal failure are common, lymph node involvement is very rare. In this case report we describe the first reported case of sarcoidosis in association with hereditary lysozyme amyloidosis. PMID:24351625

  1. Two Case Reports on Thalamic and Basal Ganglia Involvement in Children with Dengue Fever.

    Science.gov (United States)

    Liyanage, Guwani; Adhikari, Lihini; Wijesekera, Saraji; Wijayawardena, Maheshaka; Chandrasiri, Suchithra

    2016-01-01

    There have been increasing numbers of case reports of dengue infection with unusual manifestations. Such unusual manifestations including acute liver failure and encephalopathy could be manifested even in the absence of significant plasma leakage. Further, severe organ involvement including nervous system involvement indicates severe dengue infection. However, neurological manifestations of dengue fever are rare. This is the first case report of dengue infection with thalamic and basal ganglia involvement in Sri Lanka. PMID:27478661

  2. Wineries' Involvement in Promoting Tourism Online: The Case of Texas

    Directory of Open Access Journals (Sweden)

    Rasch, Leslie

    2008-04-01

    Full Text Available Wine tourism has become an important driver of business for wineries in many regions around the world, while Texas wine regions are only starting to emerge as important tourism destinations. A study was conducted to investigate how effectively Texas wineries market tourism to their own establishments as well as in a regional context. A specific focus was placed on indications of collaborative wine tourism marketing practices on winery websites. The results indicate that wineries provide basic visitor information but are missing out on strategic opportunities to market wine tourism to their areas.

  3. Broadening public participation in systematic reviews: a case example involving young people in two configurative reviews

    OpenAIRE

    Oliver, K.; R. Rees; Brady, L. M.; Kavanagh, J; Oliver, S; Thomas, J.

    2015-01-01

    Arguments supporting the involvement of users in research have even more weight when involving the public in systematic reviews of research. We aimed to explore the potential for public involvement in systematic reviews of observational and qualitative studies.

  4. [A case of HTLV-1 associated myelopathy with pulmonary involvement].

    Science.gov (United States)

    Araki, J; Kaku, M; Mashimoto, H; Fukuda, Y; Asai, S

    1989-11-01

    A 70-year-old woman was admitted complaining of gait disturbance and difficulty in urination. Neurological examination showed myelopathy and both serum and CSF anti ATLA antibodies were positive. A diagnosis of HTLV-associated myelopathy (HAM) was made and steroid therapy was initiated. Chest X-ray film on admission showed no abnormality, but three months later, diffuse fine nodular and reticular shadows appeared in both lung fields. The patients had no respiratory symptom. The results of pulmonary function tests were normal, aside from a mild obstructive defect as indicated by reduced V25. Arterial blood gas was also normal. Bronchoalveolar lavage studies showed increased total cell counts and an increased proportion of T-cells. The histological findings of the transbronchial lung biopsy specimen were bronchiolitis and alveolitis. Subsequently, within the next eight months the abnormal shadows on chest X-ray cleared gradually on maintenance dosage of prednisolone, 10 mg/day. Possible relationships between HAM and the pulmonary lesions were discussed. PMID:2625816

  5. Examples and Case Studies

    NARCIS (Netherlands)

    Asbach, C.; Aguerre, O.; Bressot, C.; Brouwer, D.H.; Gommel, U.; Gorbunov, B.; Bihan, O. le; Jensen, K.A.; Kaminski, H.; Keller, M.; Koponen, I.K.; Kuhlbusch, T.A.J.; Lecloux, A.; Morgeneyer, M.; Muir, R.; Shandilya, N.; Stahlmecke, B.; Todea, A.M.

    2014-01-01

    Release of nanomaterials may occur during any stage of the life-cycle and can eventually lead to exposure to humans, the environment or products. Due to the large number of combinations of release processes and nanomaterials, release scenarios can currently only be tested on a case-by-case basis. Th

  6. Association between the Interaction of Key Genes Involved in Effector T-Cell Pathways and Susceptibility to Develop allergic Rhinitis: A Population-Based Case-Control Association Study.

    Directory of Open Access Journals (Sweden)

    Yuan Zhang

    Full Text Available Evidence suggests that interaction between key genes mediating signaling and transcriptional networks involving effector T-cell responses may influence an individual's susceptibility to develop allergic rhinitis(AR.The aim of this study was todetermine whether specific interactions between key genes involved in effector T-cell pathways are associated with an individual's susceptibility to develop AR in Han Chinese subjects.A cohort of 489 patients with AR and 421 healthy controls was enrolled from the Han Chinese population in Beijing, China. AR was established by questionnaire and clinical examination, and peripheral blood was drawn from all subjects for DNA extraction. A total of 96 single nucleotide polymorphisms (SNPs in 26 reprehensive candidate genes involved in T helper 1 (Th1, Th2, Th17, Th9 and T regulatory cell pathways were selected from the International Haplotype Mappingdatabase for Han Chinese in Beijing (CHB population, and IlluminaGoldenGate assay was conducted for SNP genotyping. The PLINK software package was used to perform statistical analyses.Simple SNP-phenotype association analysis using logistic regression showed SNP rs8193036 in IL17A gene, rs2569254 in IL-12 and rs1898413 in RORα weresignificantlyassociatedwith AR.Simple SNP-phenotype association analysis with genetic models demonstrated thatrs2569254 in IL-12, rs1031508 in STAT4, and rs3741809 in IL-26 were likely to be recessive, rs8193036 in IL17A allelic, rs897200in STAT4 genotypic, and rs1898413 in RORα dominant. Epistasis analyses exhibited that 83 SNPs in 23 genes were significantly interactive; of which 59 interactions/SNP pairs demonstrated OR values higher than 2 or lower than 0.5, and 12 interactions/SNP pairs OR values higher than 4 or lower than 0.25. STAT3, RORα and IL-26, involved in Th17 pathway,were the mostfrequentlyinteractive genes.This study suggests that interactions between several SNPs in key genes involved in effector T-cell pathways are

  7. KAIZEN – A case study

    Directory of Open Access Journals (Sweden)

    Manjunath Shettar

    2015-05-01

    Full Text Available The ultimate objective of manufacturing industries is to increase productivity with high quality. At present, many manufacturing companies are facing problems such as high quality rejection, high inventories, high lead time, high costs of production, and inability to cope with customer orders. By implementing and practicing the lean production system many problems can be solved without employing high-tech and high-touch approaches but by involving people on the shop floor in Kaizen activities. Kaizen is one of the powerful tools of lean manufacturing. Kaizen refers to continuous improvement in performance, cost and quality. Kaizen ensures that manufacturing processes become leaner and fitter, but eliminate waste (problem where value is added. The main objective of this paper is to provide a background on kaizen, present an overview of kaizen concepts that are used to transform a company into a high performing lean enterprise. A case study of implementation of Kaizen‟s has been discussed.

  8. Termination: A Case Study.

    Science.gov (United States)

    Friedberg, Ahron L

    2015-12-01

    In this article I posit and examine certain criteria and qualities for ending an analysis. The case study describes the end phase of a four-year psychoanalysis in which the patient's decision to move to another area forced the end of his analysis. We continued to explore and work through his core neurotic conflicts that included issues of competitive rivalry, dominance and submission, control, and anxiety about birth and death. A shift in the transference from me as a negative father to me as a supportive but competitive older brother was also examined in the context of ending treatment as well as other aspects of the transference. In addition, we analyzed the meaning of his ending treatment based on an extra-analytic circumstance. In discussing this phase of treatment, the definition and history of the term "termination" and its connotations are reviewed. Various criteria for completing an analysis are examined, and technical observations about this phase of treatment are investigated. It was found that while a significant shift in the transference occurred in this phase of the patient's analysis, conflicts related to the transference were not "resolved" in the classical sense. Terminating treatment was considered as a practical matter in which the patient's autonomy and sense of choice were respected and analyzed. PMID:26583444

  9. Chinese immigrant entrepreneurs’ involvement in internationalization and innovation: Three Canadian cases

    DEFF Research Database (Denmark)

    Zhang, Xiaotian; Vissak, Tiia

    2014-01-01

    international immigrant entrepreneurship literature by studying Chinese immigrant entrepreneurs’ roles in their firms’ international and innovative activities in Canada, China, and other countries. It is based on three cases of Chinese entrepreneurs who established businesses in Canada. We conclude that these...... immigrants’ experience of doing business in China and Canada, their network relationships and knowledge of these markets quickened their firms’ internationalization considerably. Moreover, these firms became active in product or service innovation as the case immigrants also involved other immigrants and...... locals. Consequently, immigrant entrepreneurs should actively use their connections both in their new country of residence and also in their previous home country, but to become even more successful, they should also reach beyond their ethnic ties....

  10. Temporal and Pontine Involvement in a Case of Herpes Simplex Encephalitis, Presenting as Kluver Bucy Syndrome - A Case Report

    Directory of Open Access Journals (Sweden)

    Suresh Thirunavukarasu

    2011-01-01

    Full Text Available Bilateral temporal and frontal lobe involvement is a common characteristic of herpes simplex encephalitis (HSE. Clinical sequelae of herpes simplex encephalitis may manifest sometimes as Kluver Bucy syndrome (KBS. In herpes simplex encephalitis, apart from frontal lobe, extra temporal involvement is rare and uncommon. We report a case of HSE manifesting clinically as KBS with a rare radiological finding of temporal and extratemporal involvement of pons.

  11. Five case studies of multifamily weatherization programs

    Energy Technology Data Exchange (ETDEWEB)

    Kinney, L; Wilson, T.; Lewis, G. [Synertech Systems Corp. (United States); MacDonald, M. [Oak Ridge National Lab., TN (United States)

    1997-12-31

    The multifamily case studies that are the subject of this report were conducted to provide a better understanding of the approach taken by program operators in weatherizing large buildings. Because of significant variations in building construction and energy systems across the country, five states were selected based on their high level of multifamily weatherization. This report summarizes findings from case studies conducted by multifamily weatherization operations in five cities. The case studies were conducted between January and November 1994. Each of the case studies involved extensive interviews with the staff of weatherization subgrantees conducting multifamily weatherization, the inspection of 4 to 12 buildings weatherized between 1991 and 1993, and the analysis of savings and costs. The case studies focused on innovative techniques which appear to work well.

  12. The Diffuse Involvement of Bilateral Breasts in the Incidence of Burkitt's Lymphoma: A Case Report

    International Nuclear Information System (INIS)

    The incidence of Burkitt's lymphoma involving both breasts is rare. We report such a case that was diagnosed by a core biopsy of a hypoechoic lesion visualized from the ultrasonographic results of a patient that was clinically suspected of mastitis

  13. Teaching Pharmacology by Case Study.

    Science.gov (United States)

    Jordan, Sue

    1997-01-01

    Using pharmacology case studies with nursing students encourages theory-practice links and infuses real-life content. Cases provide rich qualitative data for evaluating curriculum. However, they are not a substitute for evidence-based practice. (SK)

  14. Microscopic polyangiitis complicated with ileal involvement detected by double-balloon endoscopy: a case report

    OpenAIRE

    Fukushima, Masashi; Inoue, Satoko; Ono, Yuichiro; Tamaki, Yoshitaka; Yoshimura, Hajime; Imai, Yukihiro; Inokuma, Tetsuro

    2013-01-01

    Background Microscopic polyangiitis is characterized by pauci-immune, necrotizing small-vessel vasculitis and an anti-neutrophil cytoplasmic antibody-associated vasculitis. Although gastrointestinal involvement in microscopic polyangiitis is not rare, endoscopic observation of it is extremely rare. To the best of our knowledge, this is the first case report of small intestinal involvement in microscopic polyangiitis detected and followed up by double-balloon endoscopy. Case presentation A 70-...

  15. Mal de Meleda with Lip Involvement: A Report of Two Cases

    OpenAIRE

    Amiya Kumar Nath; Sangita Chaudhuri; Devinder Mohan Thappa

    2012-01-01

    Mal de Meleda is a rare autosomal recessive transgradient palmoplantar keratoderma characterized by transgradient keratoderma with associated scleroatrophy, nail changes, pseudoainhum around digits and perioral erythema, without a tendency for spontaneous resolution. Involvement of the lip by keratoderma has not been reported in the English literature. Here we present two cases of Mal de Meleda with unusual lip involvement. The first case was a 15-year-old girl, born of second-degree consangu...

  16. A Pilot Study Involving the Effect of Two Different Complex Training Protocols on Lower Body Power

    OpenAIRE

    Smith Chad E.; Lyons Brian; Hannon James C.

    2014-01-01

    Purpose. Complex training (CT) involves the coupling of two exercises ostensibly to enhance the effect of the second exercise. Typically, the first exercise is a strength exercise and the second exercise is a power exercise involving similar muscles. In most cases, CT is designed to enhance power. The purpose of this study was twofold. First, this study was designed to determine if lower body power could be enhanced using complex training protocols. Second, this study investigated whether the...

  17. Intercultural Communicative Case Study

    Institute of Scientific and Technical Information of China (English)

    吴冬梅

    2009-01-01

    The essay is mainly about the author's comprehension of cultural differences and intercultural communication after reading the book Communication Between Cultures.In addition,the author also analyses three cases with the theories and approaches mentioned in Communication Between Cultures.

  18. Purchase Involvement of New Car Buyers: A Descriptive Study

    OpenAIRE

    Joseph Abramson; Peggy D. Brewer

    1993-01-01

    The purchase of a new automobile is often cited as the quintessence of a high involvement purchase decision; the financial risks and personal relevance of the purchase dictate that car buyers put forth much effort before making a decision. In this research such efforts as dealers shopped, brands shopped, and information sources used are studied in a large sample of new car buyers in West Virginia. The purchase behavior of respondents in this study seems more like low-involvement than high inv...

  19. Tracheal involvement of bronchus-associated lymphoid tissue lymphoma: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, Kyung Sik; Jeon, Kyung Neough; Kang, Duk Sik [College of Medicine, Kyungpook National Univ., Taegu (Korea, Republic of)

    2002-01-01

    Primary malignant tumors of the trachea are rare, the most prevalent histologies beeing squamous cell and adenoid cystic carcinoma. A review of the literature revealed only ten cases of primary tracheal or bronchial non-Hodgkin's lymphoma. We describe a case in which tracheal involvement of bronchus-associated lymphoid tissue lymphoma, a subtype of non-Hodgkin's lymphoma, occurred.

  20. Disrupt, Support and Document: The Role of Social Media in International Parental Child Abduction Cases Involving Japan

    Directory of Open Access Journals (Sweden)

    Geraldine Carney

    2016-07-01

    Full Text Available In this article, I examine the use of social media by parents involved in cases of international parental abduction to and from Japan, with a focus on cases of abduction to Japan. I argue that the use of social media in these cases is a symptom of and a counter to a legal system which has been outpaced by changes in society, particularly the creation and dissolution of international families. This article discusses a number of case studies of social media usage and locates these in the context of the contemporary Japanese legal system. While not ignoring the nefarious potential of social media usage, I come to a positive assessment of its use in cases of international parental child abduction involving Japan. I also question how its utility will change over time, depending on the legal system’s ability to adapt to societal changes and expectations.

  1. Mucous membrane pemphigoid with exclusive gingival involvement: Report of a case and review of literature

    Directory of Open Access Journals (Sweden)

    Shamimul Hasan

    2012-01-01

    Full Text Available According to Sir William Osler, Mouth is the mirror of the body which reflects systemic -diseases. The oral mucosa may be affected by a variety of mucocutaneous diseases and oral lesions may occur first or very early in several mucocutaneous disorders. The erosive gingival lesions associated with vesiculobullous diseases such as lichen planus, cicatricial pemphigoid, and pemphigus vulgaris have been collectively referred to as "Desquamative gingivitis" (DG. Gingival desquamation is a clinical sign in which the gingiva appears reddish, painful, glazed and friable with destruction of the epithelium. This gingival desquamation is due to various disease processes in gingiva. The disease process may be a localized disease of gingiva or a systemic disease which manifests in the gingiva. It is important to be aware of this rare clinical entity so as to distinguish DG from plaque induced gingivitis which is an extremely common condition, easily recognized and treated daily by the dental surgeon. Accurate diagnosis and effective treatment of these lesions may greatly diminish or reverse disease progression. Here by, we present a case of mucous membrane pemphigoid presenting as gingival desquamation in a 45 year old female. Our patient presented with generalized erythematous gingiva and gingival desquamation involving the free, attached and marginal gingiva of left maxillary and mandibular dentition. However, other mucosal and skin involvement was not appreciated in the present case. Thorough history, clinical examination, histopathology and immunofluorescence studies helped us to arrive at the diagnosis of this rare sub-epithelial blistering disorder.

  2. Carcinoma involving the gallbladder: a retrospective review of 23 cases - pitfalls in diagnosis of gallbladder carcinoma

    Directory of Open Access Journals (Sweden)

    Giang Tran H

    2012-01-01

    Full Text Available Abstract Background Carcinoma of the gallbladder (GBC clinically mimics benign gallbladder diseases and often escapes detection until advanced stage. Despite the frequency of cholecystectomy, diagnosis of GBC remains problematic in many situations. We sought to identify pathologic features that contribute to the difficulty in recognition of GBC. Methods We identified 23 patients (ranged from 45 to 86 years, male to female ratio 1:4.5 with carcinoma involving the gallbladder referred to an academic medical center over a period of 10 years for study. This includes 10 cases of primary GBC, 6 cases of metastatic tumor to gallbladder, 6 cases of directly invasive adenocarcinoma arising elsewhere in the biliary tree, and one case of unidentified origin adenocarcinoma. Primary tumors include adenocarcinoma not otherwise specified (NOS in 6 cases, papillary adenocarcinoma in 2 cases, and single cases of undifferentiated carcinoma and combined adenocarcinoma and neuroendocrine carcinoma (NEC. Metastatic tumors to gallbladder were from a wide range of primary sites, predominantly the gastrointestinal tract. Results These cases illustrate seven potential pitfalls which can be encountered. These include: 1 mistakenly making a diagnosis of adenocarcinoma of gallbladder when only benign lesions such as deeply penetrating Rokitansky-Aschoff sinuses are present (overdiagnosis, 2 misdiagnosing well-differentiated invasive carcinoma with minimal disease as benign disease (underdiagnosis, 3 differentiating between primary NEC of gallbladder and metastasis, 4 confusing primary mucinous adenocarcinoma of gallbladder with pseudomyxoma peritonei from a low grade appendiceal neoplasm disseminated to gallbladder, 5 confusing gangrenous necrosis related to cholecystitis with geographic tumoral necrosis, 6 undersampling early, grossly occult disease, and 7 misinterpreting extracellular mucin pools. Conclusions Clinical history and a high index of suspicion are

  3. Case Study - "Marketing Christmas"

    Institute of Scientific and Technical Information of China (English)

    何青青

    2011-01-01

    @@ The following is based on a real case but the name of the company has been changed and the source will only be revealed after the submission deadline.It is June in Eastern China and temperatures are over 30 degrees Celsius.In Huang Yi-Ju's wholesale showroom, based in Yiwu, model Father Christmases line the shelves, fill the floors and scale the walls.

  4. Assessing parental risk in parenting plan (child custody) evaluation cases involving internet sexual behavior

    OpenAIRE

    Witt, Philip H.; Merdian, Hannah Lena; Connell, Mary; Douglas P. Boer

    2010-01-01

    One type of claim in parenting assessment (child custody)1 cases is that one parent, typically the father, is alleged to be engaging in improper or compulsive sexual behavior via the Internet. The sexual behavior at issue can range from frequent sexually explicit chats with other adults to compulsive viewing of adult pornography. In more extreme cases, the problematic behavior may involve viewing child pornography, and in some cases the parent faces actual criminal charges in this regard. The...

  5. Case Study: Case Studies and the Flipped Classroom

    Science.gov (United States)

    Herreid, Clyde Freeman; Schiller, Nancy A.

    2013-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses the positive and negative aspects of the "flipped classroom." In the flipped classroom model, what is normally done in class and what is normally done as…

  6. Building theories from case study research: the progressive case study

    NARCIS (Netherlands)

    Steenhuis, Harm-Jan; Bruijn, de Erik J.

    2006-01-01

    Meredith (1998) argues for more case and field research studies in the field of operations management. Based on a literature review, we discuss several existing approaches to case studies and their characteristics. These approaches include; the Grounded Theory approach which proposes no prior litera

  7. Theory Testing Using Case Studies

    DEFF Research Database (Denmark)

    Møller, Ann-Kristina Løkke; Dissing Sørensen, Pernille

    2014-01-01

    testing using case studies, including the associated research goal, analysis, and generalisability. We argue that research designs for theory testing using case studies differ from theorybuilding case study research designs because different research projects serve different purposes and follow different......The appropriateness of case studies as a tool for theory testing is still a controversial issue, and discussions about the weaknesses of such research designs have previously taken precedence over those about its strengths. The purpose of the paper is to examine and revive the approach of theory...... research paths....

  8. The emotional involvement in the workplace: An empirical study

    Directory of Open Access Journals (Sweden)

    Ana María Lucia-Casademunt

    2012-06-01

    Full Text Available Purpose: In a multitude of studies, it is verified that the generation of positive attitudes for employees such as job satisfaction or job involvement, have a positive influence on productivity levels of companies. The current investigation focus on the identification of employee-profile -who is emotionally involved with their work activity- through the use of a set of individual, job related and attitudinal factors.Design/methodology: A review of the literature about the main factors that affect the job involvement particularly on its emotional dimension has been completed. For its measurement at the empirical level, various items related to psychological well being of employees included in the IV European Working Conditions Survey-2010 are used. Moreover, those items are identified in Job Involvement Questionnaire (Lodahl & Kejner, 1965. Since then, an empirical and multidimensional study is carried out by applying a logistic regression model on the sample of 11,149 employees obtained with European survey cited previously.Findings: The logistic regression model identifies the factors, which are directly related to emotional involvement at the workplace. Ultimately, is raised a definitive model that define the European employee-profile -who is emotionally involved at the workplace-: a rather aged person who has been working at his/her present place of employment for several years in a medium-sized company where possibly there exist a good working relationship between workers and their superiors –social support-. These employees are “white-collar” workers, have career advancement opportunities in the organizational hierarchy. They perform variety, flexible and complex tasks, which leads to satisfaction in terms of pay and working conditions.Research limitations/implications: Emotional involvement has been measured through self-awareness and, therefore, the corresponding bias in the key variable must be assumed. In addition, the casual

  9. Theory testing using case studies

    DEFF Research Database (Denmark)

    Dissing Sørensen, Pernille; Løkke Nielsen, Ann-Kristina

    Case studies may have different research goals. One such goal is the testing of small-scale and middle-range theories. Theory testing refers to the critical examination, observation, and evaluation of the 'why' and 'how' of a specified phenomenon in a particular setting. In this paper, we focus...... on the strengths of theory-testing case studies. We specify research paths associated with theory testing in case studies and present a coherent argument for the logic of theoretical development and refinement using case studies. We emphasize different uses of rival explanations and their implications for research...... design. Finally, we discuss the epistemological logic, i.e., the value to larger research programmes, of such studies and, following Lakatos, conclude that the value of theory-testing case studies lies beyond naïve falsification and in their contribution to developing research programmes in a progressive...

  10. Three Community College Case Studies

    Science.gov (United States)

    Wojtysiak, Joseph; Sutton, William J., II; Wright, Tommy; Brantley, Linda

    2011-01-01

    This article presents three case studies that focus on specific projects that are underway or have been completed. In the first case study, Joseph Wojtysiak and William J. Sutton, II discuss the Green Center of Central Pennsylvania, which is designed to serve as the state's preeminent source for education, training and public information about…

  11. Canadian Mock Juror Attitudes and Decisions in Domestic Violence Cases Involving Asian and White Interracial and Intraracial Couples

    Science.gov (United States)

    Maeder, Evelyn M.; Mossiere, Annik; Cheung, Liann

    2013-01-01

    This study manipulated the race of the defendant and the victim (White/White, White/Asian, Asian/Asian, and Asian/White) in a domestic violence case to examine the potential prejudicial impact of race on juror decision making. A total of 181undergraduate students read a trial transcript involving an allegation of spousal abuse in which defendant…

  12. A case of Salla disease with involvement of the cerebellar white matter

    Energy Technology Data Exchange (ETDEWEB)

    Linnankivi, T.; Loennqvist, T. [Department of Paediatric Neurology, Hospital for Children and Adolescents, University of Helsinki (Finland); Autti, T. [Department of Radiology, Helsinki University Central Hospital, University of Helsinki, P.O. Box 340, FIN-00029 HUCH (Finland)

    2003-02-01

    Salla disease (SD) is a lysosomal disorder manifesting in infancy with hypotonia, nystagmus, ataxia and retarded motor development. MRI typically shows hypomyelination confined to the cerebral white matter. We describe a patient with two MRI studies in addition to repeated urine examinations. This case was problematic because the first urine examination did not show the elevation of free sialic acid typical of SD and MRI was also atypical, with abnormal signal intensity in cerebellar white matter. We recommend repeated urinary examinations and a search for SLC17A5 mutations in patients with cerebral signal intensity abnormalities typical of SD and emphasise that cerebellar white-matter involvement on MRI does not exclude the diagnosis. (orig.)

  13. MYC translocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation

    DEFF Research Database (Denmark)

    Leucci, E; Cocco, M; Onnis, A;

    2008-01-01

    at the standardization of FISH procedures in lymphoma diagnosis, we found that five cases out of 35 classic endemic BLs were negative for MYC translocations by using a split-signal as well as a dual-fusion probe. Here we investigated the expression pattern of miRNAs predicted to target c-Myc, in BL cases, to clarify...... whether alternative pathogenetic mechanisms may be responsible for lymphomagenesis in cases lacking the MYC translocation. miRNAs are a class of small RNAs that are able to regulate gene expression at the post-transcriptional level. Several studies have reported their involvement in cancer...... was observed in BL cases, compared to normal controls. More interestingly, hsa-mir-34b was found to be down-regulated only in BL cases that were negative for MYC translocation, suggesting that this event might be responsible for c-Myc deregulation in such cases. This hypothesis was further confirmed by our...

  14. Case study - Argentina

    International Nuclear Information System (INIS)

    Antecedents and experience of nuclear activities in Argentina; the Atomic Energy Commission (CNEA). First development and research activities. Research reactors and radioisotopes plants. Health physics and safety regulations. - Feasibility studies for the first nuclear power plant. Awarding the first plant CNA I (Atucha I). Relevant data related to the different project stages. Plant performance. - Feasibility study for the second nuclear power plant. Awarding the second plant CNE (Central Nuclear Embalse). Relevant data related to established targets. Differences compared with the first station targets. Local participation. Plant performance. (orig./GL)

  15. Pituitary involvement in Wegener ' s granulomatosis: a case report and review of the literature

    Institute of Scientific and Technical Information of China (English)

    陶建瓴; 董怡

    2003-01-01

    Wegener ' s Granulomatosis (WG) is a multi-system disorder characterized by necrotizing granulomas in the upper and/or lower respiratory tract, with or without focal necrotizing glomerulonephritis and other systemic vasculitis.1 Clinical manifestations may vary with the site of involvement and the extension of the lesions. Pituitary involvement is rare, and to our knowledge no more than ten cases with this complication have been published in the literature in English. We report here an additional WG case complicated by pan-hypopituitarism.

  16. Miliary Tuberculosis with Concurrent Brain and Spinal Cord Involvement: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Sung, Chang Keun; Na, Hyoung Il; Yu, Hyeon; Byun, Jun Soo; Youn, Young Chul; Seo, Jae Seung; Kim, Gi Hyeon [Chung-Ang University, Seoul (Korea, Republic of)

    2008-11-15

    Central nervous system involvement by tuberculosis is rare, and intramedullary involvement is even more rare. A patient that developed intermittent amnesia during anti-tuberculous therapy underwent brain CT and MRI and spine MRI. The latter showed multiple small enhancing nodules in the brain and spinal cord. The patient was treated with anti-tuberculous medication and steroids under the suspected diagnosis of miliary tuberculosis. Follow-up CT showed decreased nodule size and number. We report a case of miliary tuberculosis in the brain and spinal cord and present a review of the literature related to similar cases.

  17. Pulmonary involvement in systemic sclerosis: An imaging study from Kashmir

    Directory of Open Access Journals (Sweden)

    Iffat Hassan

    2015-01-01

    Full Text Available Background: Systemic sclerosis (SS is a chronic, multisystem collagen vascular disorder of undefined etiology, whose prognosis and overall survival is determined by visceral especially the lung involvement. Aim: To evaluate the pulmonary involvement in SS by imaging methods. Materials and Methods: Clinical examination, pulmonary function tests, chest X-ray and high resolution computed tomography (HRCT scans were carried out in a series of 25 patients prospectively over a period of 3 years (2009-2011AD. Results: Of the total 25 patients of the study, the group with abnormal HRCT chest (n = 20, 16 had clinical symptoms of respiratory involvement, only 7 had an abnormal chest X-ray and 15 had abnormal forced expiratory volume/forced vital capacity (FEV1/FVC spirometric parameter. While the group with normal HRCT chest (n = 5, 1 had clinical symptoms of respiratory involvement and 4 had abnormal FEV1/FVC spirometric parameter. The differences in these parameters between the two groups were statistically significant, while the differences for mean skin tethering index, mean disease duration and female/male sex ratio were statistically meaningless. Most common HRCT finding observed in the study was ground glass opacities (GGO (9/20. Only 4 of total 9 patients who had only GGO in HRCT were symptomatic for respiratory involvement as compared to 100% (11/11 in the group who had HRCT findings other than or in addition to GGO. Conclusion: The HRCT outscores Chest X-ray in detecting early lung involvement in SS patients more so early in the course of the disease thereby underscoring its importance in identifying SS patients who will be potential candidates for early institution of therapy that might reverse/limit pulmonary involvement by the disease.

  18. Prodominant hypertensive brainstem encephalopathy with supratentorial involvement: Case report and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ji Hee; Park, Sung Tae; Lim, Hyun Kyung [Dept. of Radiology, Soonchunhyang University Hospital, Soonchunhyang University School of Medicine, Seoul (Korea, Republic of); Kim, Sung Tae; Cha, Ji Hoon [Dept. of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2014-12-15

    Hypertensive encephalopathy typically presents with bilateral parietooccipital vasogenic edema. Brainstem and cerebellar edema are uncommon in association with typical supratentorial changes. We experienced three cases of atypical hypertensive encephalopathy involving brainstem and cerebellum as well as cerebral white matter, which showed characteristic alternating linear bright and low signals in the pons, the so-called 'stripe sign'. We report these cases here with a brief literature review.

  19. Imaging manifestations of intravascular leiomyoma involving the right atrium: a case report and literature review

    Science.gov (United States)

    Ouyang, Aimei; Su, Xinyou; Li, Shujing; Li, Kun; Wang, Jian

    2015-01-01

    The aim of this study is to investigate the imaging features of intravascular leiomyoma (IVL) involving the heart and the imaging techniques in the diagnosis of this disease. The imaging features of contrast-enhanced computed tomography (CT), the clinical data and the pathological data of a case of IVL involving the right atrium were retrospectively analyzed and the literatures were reviewed. A 42-year-old woman was admitted to Jinan Central Hospital with a 7-day history of lower extremity weakness, chest tightness and short breath. Contrast-enhanced CT scanning revealed that there was a mass in the inferior vena cava and right atrium, which was heterogeneously enhanced. There was a gap between the vessel wall and the mass. Spiral CT scanning with multiplanner reformation (MPR) reconstruction revealed the morphology, scope and extension pathways of the tumor clearly. Ultrasonography (US) and magnetic resonance imaging (MRI) also played important roles in the diagnosis and differential diagnosis of IVL. To the patients with a history of uterine fibroids, spiral CT scanning, US and MRI could be used to improve the correct diagnosis rates of IVL before surgery. PMID:26379990

  20. Magnifying Endoscopic Features of Follicular Lymphoma Involving the Stomach: A Report of Two Cases

    Science.gov (United States)

    Takata, Katsuyoshi; Kawano, Seiji; Fujii, Nobuharu; Kawahara, Yoshiro; Yoshino, Tadashi; Okada, Hiroyuki

    2016-01-01

    A 70-year-old woman presented with follicular lymphoma involving the stomach, duodenum, jejunum, bone, and lymph nodes. Esophagogastroduodenoscopy revealed multiple depressed lesions in the stomach. Examination with magnifying endoscopy showed branched abnormal vessels along with gastric pits, which were irregularly shaped but were preserved. The second case was a 45-year-old man diagnosed with stage II1 follicular lymphoma with duodenal, ileal, and colorectal involvement, as well as lymphadenopathy of the mesenteric lymph nodes. Esophagogastroduodenoscopy performed six years after the diagnosis revealed multiple erosions in the gastric body and angle. Magnifying endoscopic observation with narrow-band imaging showed that the gastric pits were only partially preserved and were destroyed in most of the stomach. Branched abnormal vessels were also seen. Pathological features were consistent with follicular lymphoma in both cases. The structural differences reported between the two cases appear to reflect distinct pathologies. Disappearance of gastric pits in the latter case seems to result from loss of epithelial cells, probably due to chronic inflammation. In both cases, branched abnormal vasculature was observed. These two cases suggest that magnified observations of abnormal branched microvasculature may facilitate endoscopic detection and recognition of the extent of gastric involvement in patients with follicular lymphoma.

  1. Final report on case studies

    DEFF Research Database (Denmark)

    Ljungberg, Daniel; McKelvey, Maureen; Lassen, Astrid Heidemann

    2012-01-01

    Case study as a research design means investigating a single or multiple instance(s) or setting(s) (i.e. a case) and its entire context to explain a phenomenon and its processes. This is achieved through detailed understanding, usually comprised of multiple sources of information. In this way, ca...

  2. "Can We Play Again with Picasso Miss?" The Effects of the Arts in Children's Involvement during Literacy Activities in the Early Years Settings: A Case Study in the Greek Context

    Science.gov (United States)

    Theodotou, Evgenia

    2015-01-01

    Involvement is the cornerstone of the educational process, especially in the early years settings. It is a fundamental factor in people's actions particularly when they are deeply concentrated in an activity. However, little research has been conducted in the early years settings, with focus on teaching and learning. This piece of research…

  3. Renal involvement in MELAS syndrome - a series of 5 cases and review of the literature.

    Science.gov (United States)

    Seidowsky, Alexandre; Hoffmann, Maxime; Glowacki, François; Dhaenens, Claire-Marie; Devaux, Jean-Philippe; de Sainte Foy, Celia Lessore; Provot, François; Gheerbrant, Jean-Dominique; Hummel, Aurelie; Hazzan, Marc; Dracon, Michel; Dieux-Coeslier, Anne; Copin, Marie-Christine; Noël, Christian; Buob, David

    2013-12-01

    Renal dysfunction is increasingly recognized as a potential clinical feature of mitochondrial cytopathies such as mitochondrial encephalomyopathy, lacticacidosis and stroke-like episodes (MELAS) syndrome. Five cases of MELAS syndrome with renal involvement from 4 unrelated families are presented in this case series. Three of the 5 patients had a history of maternally-inherited diabetes and/or deafness. Focal and segmental glomerulosclerosis and arteriolar hyaline thickening were the most striking findings on renal biopsy. In addition to clinical presentation with the typical symptoms of MELAS syndrome, genetic testing in these patients identified the A3243G point mutation in the tRNALeu gene of the mitochondrial DNA (mtDNA). The diagnosis of MELAS syndrome was thus considered to be unequivocal. The incidence of kidney disease in MELAS syndrome may be underestimated although a study is required to investigate this hypothesis. As the A3243G mtDNA mutation leads to a progressive adult-onset form of focal segmental glomerulosclerosis (FSGS), screening for the MELAS A3243G mtDNA mutation should therefore be performed especially in patients with maternally-inherited diabetes or hearing loss presenting with FSGS.

  4. TB or not TB?: a case of isolated testicular TB with scrotal involvement.

    LENUS (Irish Health Repository)

    Bhargava, A

    2009-06-01

    Despite the genitourinary tract being the most common site affected by extrapulmonary TB, isolated testicular TB remains a rare clinical entity. In patients with co-morbidities such as hepatic impairment, treatment proves a challenge, as first-line hepatotoxic pharmaceuticals are contraindicated. Here, we report a case of isolated testicular TB with scrotal involvement, on a background of hepatic dysfunction.

  5. Spinal capillary hemangioma involving the lumbar epidural and paraspinal spaces: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Yim, Bong Guk; Lee, Young Jun; Lee, Ji Young; Park, Chan Kum; Paik, Seung Sam [Hanyang University Medical Center, Hanyang University College of Medicine, Seoul (Korea, Republic of); Park, Dong Woo [Dept. of Radiology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Seoul (Korea, Republic of)

    2015-07-15

    Spinal capillary hemangiomas in the epidural space are extremely rare; however, a preoperative radiological diagnosis is very important because of the risk of massive intraoperative hemorrhage. We report a case of a spinal capillary hemangioma involving the lumbar epidural and paraspinal spaces.

  6. Tuberous sclerosis: Ultrasound, CT and MRI features of two cases with multiple organ involvement

    International Nuclear Information System (INIS)

    The cases of two patients with tuberous sclerosis with multiple sites of involvement are presented. Both patients had characteristic cerebral lesions of tuberous sclerosis associated with bilateral renal angiomyolipomas and hepatic hamartomas. Additionally there were diffuse pulmonary cystic changes in one patient and cardiac rhabdomyoma in the other. Copyright (1998) Blackwell Science Pty Ltd

  7. A Randomized Trial of Probation Case Management for Drug-Involved Women Offenders

    Science.gov (United States)

    Guydish, Joseph; Chan, Monica; Bostrom, Alan; Jessup, Martha A.; Davis, Thomas B.; Marsh, Cheryl

    2011-01-01

    This article reports findings from a clinical trial of a probation case management (PCM) intervention for drug-involved women offenders. Participants were randomly assigned to PCM (n = 92) or standard probation (n = 91) and followed for 12 months using measures of substance abuse, psychiatric symptoms, social support, and service utilization.…

  8. 14 CFR 302.211 - Procedures in certificate cases involving initial or continuing fitness.

    Science.gov (United States)

    2010-01-01

    ... initial or continuing fitness. 302.211 Section 302.211 Aeronautics and Space OFFICE OF THE SECRETARY... Disposition of Applications § 302.211 Procedures in certificate cases involving initial or continuing fitness... applicant's fitness to operate. Where such applications propose the operation of scheduled service...

  9. Case Study: del Amo Bioventing

    Science.gov (United States)

    The attached presentation discusses the fundamentals of bioventing in the vadose zone. The basics of bioventing are presented. The experience to date with the del Amo Superfund Site is presented as a case study.

  10. Nasopharyngeal Case-Control Study

    Science.gov (United States)

    A case-control study conducted in Taiwan between 1991-1994 among approximately 1,000 individuals to examine the role of viral, environmental, and genetic factors associated with the development of nasopharyngeal carcinoma

  11. Cysticercosis Involving Muscle of Mastication: A Review and Report of Two Cases

    Directory of Open Access Journals (Sweden)

    Sarbjeet Singh

    2013-01-01

    Full Text Available Cysticercosis is a parasitic infection caused by the larval stages of the parasitic cestode, Taenia solium. It is a common disease in developing countries where it is also endemic. The central nervous system (CNS is the most important primary site of infection and the disease can present with solitary or multiple space occupying lesions. Cases of cysticercosis presenting as isolated muscle mass (pseudotumours without involvement of the CNS have also been recently described in the literature. We present two cases who presented to us with pain, swelling, and tenderness involving the temporalis muscle along with trismus. Ultrasonography and MRI findings were suggestive of cysticercosis involving the temporalis muscle which resolved after the albendazole therapy.

  12. Department Involvement in Instructional Materials Development for ODL Study at the Zimbabwe Open University (ZOU)

    Science.gov (United States)

    Tanyanyiwa, Vincent Itai; Mutambanengwe, Betty

    2015-01-01

    The teaching and designing of modules at Zimbabwe Open University (ZOU) is the principal responsibility of a single body of teaching staff, although some authors and content reviewers could be sourced from elsewhere if they are not available in ZOU. This survey, through a case study, examines the involvement of lecturers and staff in the…

  13. Cryostat design case studies, principles and engineering

    CERN Document Server

    2016-01-01

    This book enables the reader to learn the fundamental and applied aspects of practical cryostat design by examining previous design choices and resulting cryostat performance. Through a series of extended case studies the book presents an overview of existing cryostat design covering a wide range of cryostat types and applications, including the magnet cryostats that comprise the majority of the Large Hadron Collider at CERN, space-borne cryostats containing sensors operating below 1 K, and large cryogenic liquid storage vessels. It starts with an introductory section on the principles of cryostat design including practical data and equations. This section is followed by a series of case studies on existing cryostats, describing the specific requirements of the cryostat, the challenges involved and the design choices made along with the resulting performance of the cryostat. The cryostat examples used in the studies are chosen to cover a broad range of cryostat applications and the authors of each case are ...

  14. Bone involvement in secondary syphilis: a case report and systematic review of the literature.

    Science.gov (United States)

    Park, Ki-Ho; Lee, Mi Suk; Hong, Il Ki; Sung, Ji-Youn; Choi, Sang-Ho; Park, Sang Ok; Shin, Myung Jin; Chung, Hye Won; Lee, Sang Hoon

    2014-09-01

    Bone involvement is an unusual manifestation of secondary syphilis, but little information is available in the English-language literature. We carried out a systematic review of the English-language literature from 1964 to 2013, describing cases of secondary syphilis with bone involvement. We also describe a case of secondary syphilis with multiple osteolytic lesions, mimicking metastatic cancer or myeloma, which was included in an analysis of 37 eligible cases of secondary syphilis with bone involvement. Of these 37 patients, 28 (76%) patients were male, and the median age was 32 years (range, 12-64 years). Eleven (30%) patients had human immunodeficiency virus (HIV) infection with a median CD4 lymphocyte count of 343 cells/mm (range, 130-689 cells/mm). The diagnosis of early syphilis was suspected based on mucocutaneous findings in 28 (76%) cases. In the remaining 9 (24%) cases, high titers of nontreponemal serologic tests were the only evidence of early syphilis. The median venereal disease research laboratory (VDRL) titer was 1:64 (range, 1:8-1:320), and median rapid plasma reagin (RPR) titer was 1:64 (range, 1:16-1:512). The bones most often affected were long bones of the limbs (n = 22) and skull (n = 21). The bone lesions were multifocal in 27 (73%) cases and osteolytic in 19 (51%) cases. The treatment of syphilitic bone lesions was medical only in most patients, and prognosis was favorable with high-dose penicillin therapy. Clinical features and outcome between HIV-uninfected and HIV-infected patients were not different. Knowledge of this rare entity may lead to early diagnosis and appropriate management. PMID:25118965

  15. Structured Controversy: A Case Study Strategy.

    Science.gov (United States)

    Herreid, Clyde Freeman

    1996-01-01

    Introduces a dynamic form of the case instruction method that involves debate and compromise. Discusses two versions of structured controversy and presents an example of structured controversy that involves the use of DNA fingerprinting in forensic medicine. (JRH)

  16. Extent of metastatic axillary involvement in 1446 cases of breast cancer.

    Science.gov (United States)

    Veronesi, U; Luini, A; Galimberti, V; Marchini, S; Sacchini, V; Rilke, F

    1990-04-01

    One thousand, four hundred and forty-six patients with carcinoma of the breast treated with Halsted mastectomy (167), Patey mastectomy (732), and conservative surgery with axillary dissection, either at the same time (340), or separately (207), were evaluated with regard to the number and distribution of axillary lymph nodes. A total of 29,378 were removed and examined, on average 20.3 per patient. The average number of nodes was 13.5 at the first level, 4.5 at the second and 2.3 at the third. The same number of nodes were removed in patients treated with extensive surgery, such as Halsted mastectomy and limited surgery such as lumpectomy and in independent axillary dissection. In 839 cases metastases were found in the axilla. The average number of involved nodes was 6.4. Out of 839 patients, the first level was the site of metastases in 828, the second level in 364 and the third in 187. When a single lymph node was involved, it was nearly always at the first level. In only 11 cases, were the second and/or third levels invaded without metastases at the first level. Therefore, the percentage of cases with skipping metastases was very low (1.3%). It appears from the present data that the spread of breast cancer to the axilla follows a regular pattern; the first level is invaded first, whilst in most cases, the second and third levels are involved only when the first is substantially affected.

  17. Swordfish bill injury involving abdomen and vertebral column: case report and review

    Directory of Open Access Journals (Sweden)

    Drossos Charalambos

    2010-10-01

    Full Text Available Abstract Background Penetrating injuries of the abdomen and spinal canal that involve organic material of animal origin are extremely rare and derive from domestic and wild animal attacks or fish attacks. Case presentation In this case report we present the unique, as far as the literature is concerned, unprovoked woman's injury to the abdomen by a swordfish. There are only four cases of swordfish attacks on humans in the literature - one resulted to thoracic trauma, two to head trauma and one to knee trauma, one of which was fatal - none of which were unprovoked. Three victims were professional or amateur fishermen whereas in the last reported case the victim was a bather as in our case. Our case is the only case where organic debris of animal's origin remained in the spinal canal after penetrating trauma. Conclusions Although much has been written about the management of penetrating abdominal and spinal cord trauma, controversy remains about the optimal management. Moreover, there is little experience in the management of patients with such spinal injuries, due to the fact that such cases are extremely rare. In this report we focus on the patient's treatment with regard to abdominal and spinal trauma and present a review of the literature.

  18. Sternocleidomastoid syndrome: a case study

    OpenAIRE

    Missaghi, Babak

    2004-01-01

    This article presents a case study of a patient diagnosed with dysfunction of the sternocleidomastoid (SCM) muscle, a condition which can result in head and face pain, nausea, dizziness, coryza, and lacrimation. In this particular case, the SCM muscle had developed tightness and weakness with presence of multiple trigger points within both heads. A combination of passive and active treatments were utilized to successfully treat this condition.

  19. Tumefactive immunoglobulin G4-related disease involving the dura mater: A case report and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Hoon; Lee, Ji Hoon; Ko, Yong; Paik, Seoung Sam; Lee, Young Jun [Dept. of Radiology, Hanyang University Hospital, Seoul (Korea, Republic of); Park, Dong Woo [Dept. of Radiology, Hanyang University Hospital, Seoul (Korea, Republic of)

    2015-08-15

    Immunoglobulin G4 (IgG4)-related disease is a well-known disorder characterized by an inflammatory reaction with an increase in the number of IgG4-positive plasma cells associated with sclerosis. IgG4-related disease often affects the dura mater with a pattern of diffuse thickening when the central nervous system is involved. However, some nodular dural thickening requires discrimination from tumors because of obviously different treatment options. We report of a case of IgG4-related disease with tumefactive dural involvement.

  20. ED-12WIDESPREAD SYSTEMIC METASTASES FROM MEDULLOBLASTOMA WITHOUT EVIDENCE OF ACTIVE CNS INVOLVEMENT: A CASE SERIES

    Science.gov (United States)

    Kumthekar, Priya; Singh, Simran; Smiley, Natasha Pillay; Lulla, Rishi

    2014-01-01

    This case series describes two patients with previously treated medulloblastoma who present with systemic metastases without evidence of central nervous system (CNS) disease. Patient #1 is male who presented at age 29 with pathology confirmed medulloblastoma treated with complete surgical resection followed by radiation (36 Gy craniospinal plus posterior fossa boost). Subsequently, he received cisplatin, cytoxan, and vincristine. One year later, he developed back pain and urinary retention. Imaging of his spine showed widespread bony metastases without parenchymal CNS disease. Biopsy of the left acetabulum confirmed metastatic medulloblastoma. He is currently enrolled on study with LDE225 versus temozolomide. Surveillance imaging to date is negative for intracranial metastasis, but does show extensive bony metastases involving the total spine, pelvis, ribs, sternum, clavicles, humeri, and femurs. Patient #2 is a female who presented at 32 years with severe headaches, nausea and vomiting found to have pathology confirmed medulloblastoma. She was lost to follow up temporarily, but presented again months later with headaches. She had a recurrent mass and underwent repeat resection. MRI of the spine showed nodular enhancement of the sacral nerve roots compatible with leptomeningeal spread. She underwent craniospinal radiation 36 Gy with a boost to the lumbar region and posterior fossa. One year after initial diagnosis, she presented with hypotension, tachycardia, and fatigue. Neuroimaging showed improved enhancement of the sacral nerve roots and brain imaging showed stable postsurgical changes. Systemic imaging, however, revealed widespread metastatic disease in the lymphatic system, liver, lung, and bones. The patient passed away a few months later. Medulloblastoma can metastasize outside the central nervous system (CNS), however typically does so concurrently with CNS progression. Here we present two adult patients with widely metastatic medulloblastoma systemically

  1. Kenya Groundwater Governance Case Study

    OpenAIRE

    Mumma, Albert; Lane, Michael; Kairu, Edward; Tuinhof, Albert; Hirji, Rafik

    2011-01-01

    This report presents a case study on groundwater governance in Kenya. The objectives of the study were to: (a) describe groundwater resource and socioeconomic settings for four selected aquifers; (b) describe governance arrangements for groundwater management in Kenya; and (c) identify the relevance of these arrangements for planning and implementing climate change mitigation measures. The ...

  2. Pulmonary and hepatic involvement of toxocariasis in an aduIt: case report

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Soo Jin; Kim, Jee Eun; Park, Chul Hi; Yang, Dal Mo [Gil Medical Center, Incheon (Korea, Republic of)

    2004-08-01

    Toxocariasis is known as visceral larva migrans in humans and it is caused by T. canis and T. catis, especially in children, but it is less commonly reported in adults. Although several cases of toxocariasis in adults have been reported, there have been no descriptions of toxocariasis involving the liver or, the lungs and the pleura. We report here on a case of T. canis infection in an immunocompetent adult with peripheral eosinophilia, elevated serum levels of Ig E and CT findings displaying multiple focal air space consolidations in the lungs, bilateral pleural effusion and low attenuated hepatic nodules.

  3. Nevus of ota with rare palatal involvement: a case report with emphasis on differential diagnosis.

    Science.gov (United States)

    Sharma, Gaurav; Nagpal, Archna

    2011-01-01

    Nevus of Ota, a dermal melanocytic nevus, is rare in the Indian subcontinent. It presents as a brown, blue, or gray patch on the face and is within the distribution of the ophthalmic and maxillary branches of the trigeminal nerve. The oral cavity is infrequently involved in nevus of Ota. Only 11 cases have been documented in the English literature. We report a rare case of intraoral nevus of Ota in a 22-year-old male patient. This paper focuses on the differential diagnosis of oral manifestations of nevus of Ota to assist in proper followup to avert malignant transformation.

  4. Nevus of Ota with Rare Palatal Involvement: A Case Report with Emphasis on Differential Diagnosis

    Directory of Open Access Journals (Sweden)

    Gaurav Sharma

    2011-01-01

    Full Text Available Nevus of Ota, a dermal melanocytic nevus, is rare in the Indian subcontinent. It presents as a brown, blue, or gray patch on the face and is within the distribution of the ophthalmic and maxillary branches of the trigeminal nerve. The oral cavity is infrequently involved in nevus of Ota. Only 11 cases have been documented in the English literature. We report a rare case of intraoral nevus of Ota in a 22-year-old male patient. This paper focuses on the differential diagnosis of oral manifestations of nevus of Ota to assist in proper followup to avert malignant transformation.

  5. Churg-Strauss Syndrome with Cardiac Involvement: A Case Report with CT and MRI Findings

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Seong Joo; Cho, Young Jun; Kim, Keum; Hwang, Cheol Mok; Kim, Dae Ho [Dept. of Radiology, Konyang University College of Medicine, Daegu (Korea, Republic of); Choi, Eu Gene [Dept. of Internal Medicine, Konyang University College of Medicine, Daegu (Korea, Republic of)

    2012-02-15

    This is a case report of Churg-Strauss Syndrome (CSS) associated with cardiac involvement which is demonstrated in chest CT and cardiac MRI (CMR) without specific cardiac symptoms. A 32-year-old woman had a 3-year history of bronchial asthma, chronic sinusitis, and otitis media. The patient had various typical findings of CSS. The patient had no specific cardiac symptoms or signs such as chest pain, palpitations, syncope, or murmur, but she had diffuse low attenuation lesions in the inner wall of the left ventricle (LV) in contrast-enhanced CT. This corresponded to the area of subendocardial hyperenhancement in delayed contrast-enhanced CMR images. She was treated with steroids for 2 months. Follow-up delayed contrast-enhanced CMR of the LV showed a decrease in the size of the subendocardial enhancement area, and she had no symptoms. Therefore, the radiologist and clinician both should pay careful attention to observe possible cardiac involvement in case of CSS.

  6. The prognostic importance of parotid involvement by head and neck squamous cell carcinoma - Case report*

    Science.gov (United States)

    Gouveia, Bruna Melhoranse; Barbosa, Maria Helena de Magalhães; Carneiro, Leonardo Hoehl; Hadj, Luzia Abrao El; Fernandes, Nurimar Conceição

    2016-01-01

    Squamous cell carcinoma (SCC) is the second-most common malignant cutaneous cancer, with 60% occurring in the head and neck region. Metastases are uncommon and imply a more conservative prognosis. This report describes a case of parotid-invasive, facial squamous cell carcinoma, highlighting the importance of its prognostic and therapeutic management. The patient is an 81-year-old female, exhibiting extensive tumoral lesions in the pre-auricular region, affecting the parotid parenchyma and implying the metastatic involvement of the intra-parotid lymph node. Parotid involvement caused by SCC in specificity tumors is discussed herein. Parotid invasion is currently recognized as an isolated variable. It affects survival rates and determines certain changes in case management, such as the broadening of resection areas and adjuvant radiotherapy. PMID:27438204

  7. Erdheim-Chester Disease With Multiorgan Involvement, Following Polycythemia Vera: A Case Report.

    Science.gov (United States)

    Iurlo, Alessandra; Dagna, Lorenzo; Cattaneo, Daniele; Orofino, Nicola; Bianchi, Paola; Cavalli, Giulio; Doglioni, Claudio; Gianelli, Umberto; Cortelezzi, Agostino

    2016-05-01

    Erdheim-Chester disease is a rare form of non-Langerhans cell histiocytosis characterized by the migration and infiltration of lipid-laden CD68, CD1a and S100 histiocytes to various target organs, which leads to the disruption of physiological tissue architecture and reactive fibrosis, and thus impairs organ function.We describe the first case of a patient with Erdheim-Chester disease with multiorgan involvement developed after 6 years from polycythemia vera diagnosis. During the follow-up, an abdominal ultrasound scan revealed the presence of dense, bilateral perinephric infiltration. A computed tomographic guided core biopsy was performed in order to identify the histological nature of this lesion, and a morphological analysis demonstrated the accumulation of foamy histiocytes surrounded by fibrosis. The BRAFV600E mutation was detected, and a diagnosis of Erdheim-Chester disease was made.The extreme rarity of Erdheim-Chester disease strongly suggests the existence of potentially common element(s) that may have contributed to the pathogenesis of both disorders. Obviously, further studies are needed to clarify the mutual roles and effects of JAK2 and BRAF mutations in this patient, as well as their possible therapeutic implications. PMID:27196481

  8. eCompetence Case Studies

    DEFF Research Database (Denmark)

    Jensen, Helle Bækkelund

    2006-01-01

    In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches.......In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches....

  9. Cervical spondylolysis in child with four levels of simultaneous involvement: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Gang Deuk; Kim, Hye Won; Jang, Sung Jo; Oh, Jung Taek [Wonkwang University School of Medicine, Gunsan (Korea, Republic of)

    2006-12-15

    Cervical spondylolysis is a rare condition, and less than 100 cases have been reported in the world literature. Cervical spondylolysis is defined as a well corticated defect in the posterior element of a cervical vertebra. Although the etiology of cervical spondylolysis is unknown, its association with dysplastic changes and spina bifida occulta suggest that the lesion is congenital. Here, we describe the radiographs and CT images of cervical spondylolysis involving four levels in a 9 year old boy.

  10. A Randomized Trial of Probation Case Management for Drug-Involved Women Offenders

    OpenAIRE

    Guydish, Joseph; Chan, Monica; Bostrom, Alan; Jessup, Martha; Davis, Thomas; Marsh, Cheryl

    2011-01-01

    This paper reports findings from a clinical trial of a probation case management (PCM) intervention for drug-involved women offenders. Participants were randomly assigned to either PCM (n=92) or standard probation (n=91), and followed for 12 months using measures of substance abuse, psychiatric symptoms, social support and service utilization. Arrest data were collected from administrative datasets. The sample (N=183) included mostly African American (57%) and White (20%) women, with a mean a...

  11. Cervical spondylolysis in child with four levels of simultaneous involvement: a case report

    International Nuclear Information System (INIS)

    Cervical spondylolysis is a rare condition, and less than 100 cases have been reported in the world literature. Cervical spondylolysis is defined as a well corticated defect in the posterior element of a cervical vertebra. Although the etiology of cervical spondylolysis is unknown, its association with dysplastic changes and spina bifida occulta suggest that the lesion is congenital. Here, we describe the radiographs and CT images of cervical spondylolysis involving four levels in a 9 year old boy

  12. Pulmonary Involvement of Peripheral T-cell Lymphoma, Unspecified: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Jin; Shim, Hyo Sub; Ham, Seok Jin; Kim, Tae Hoon; Kim, Sang Jin [Gangnam Severance Hospital, Seoul (Korea, Republic of)

    2010-01-15

    Peripheral T-cell lymphoma is a rare type of lymphoma that's derived from postthymic lymphoid T cells. Pulmonary involvement of peripheral T-cell lymphoma of the unspecified type is very rare and the imaging findings of this illness have rarely been reported. We present here a case of peripheral T-cell lymphoma of the unspecified type with a cavitary lesion in the lung parenchyma, and we pathologically confirmed this illness by performing video-assisted thoracoscopic surgery.

  13. Magnetic Resonance Finding of Acute Marchiafava-Bignami Disease with Diffuse Involvement: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Heo, Young Jin; Jeong, Hae Woong; In, Hyun Sin [Dept. of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of)

    2011-11-15

    Marchiafava-Bignami disease (MBD) is a rare toxic disorder strongly associated with chronic alcoholism. It is characterized by progressive demyelination and necrosis of the corpus callosum. The process may extend to neighboring white matter and subcortical regions. We report a case of MBD in which fluid-attenuated inversion recovery and diffusion-weighted imaging revealed symmetrical hyperintense lesions with diffuse involvement of the corpus callosum, white matter, corticospinal tract, internal capsule, and middle cerebellar peduncle.

  14. Case Study on Logistics Performance

    Directory of Open Access Journals (Sweden)

    Shahryar Sorooshian

    2013-05-01

    Full Text Available The paper presents research carried out at a medium‐size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and we include a theoretical discussion of online data collected and a case study of the logistic performance of a real organization. The study also examines the performance of the selected company, identifies the problems and provides recommendations for improvements. This study can be a guide for business advisers and those interested in analysing company performance, especially from a logistics viewpoint. We also suggest the methodology of this case study for those who want to have a better understanding of a business environment before starting their own business, or for benchmarking practice during strategic planning.

  15. FAMILY INVOLVEMENT ACTIVITIES AT PRESCHOOL EDUCATIONAL INSTITUTIONS: CASE OF DENIZLI PROVINCE

    Directory of Open Access Journals (Sweden)

    Hülya GÜLAY OGELMAN

    2014-06-01

    Full Text Available The purpose of this study is to investigate family involvement activities at preschool educational institutions in province of Denizli. 25 female teachers working at preschool educational institutions under Ministry of National Education in city centre of Denizli were included in the study. The results revealed that while a great majority of 32 family involvement activities included in the questionnaire (parents' corner, posters, education board, communication board, brochures, booklets, periodicals-newspapers, newsletters, correspondences, photographs, phone/ internet calls, video/tape records, conferences, home visits, article box, request box, parents' libraries, family involvement to non-classroom activities, diaries, family involvement into management and decision-making process, group meeting weren’t performed, 11 activities were implemented. While 4 of 11 activities were performed by all teachers, there were teachers who didn't perform 7 family involvement activities (parents' meetings, individual interview, development reports, collective files, involvement to classroom activities, invitation of parents to the school in special occasions, activities held at home. Considering the reasons why twenty two family involvement activities were not performed; lack of space, time and possibilities was the most frequent reason. Home visits took place on the top among family involvement activities the teachers had difficulties at most. The individual interviews were among activities conducted by the teachers in the easiest/ comfortable way.

  16. Brucella spondylodiscitis: Multifocal involvement in thoracic and lumbar areas; a rare case

    Directory of Open Access Journals (Sweden)

    Pınar Korkmaz

    2015-09-01

    Full Text Available Brucellosis is a zoonosis that can affect many organs or systems. Musculoskeletal system is the most commonly affected site in brucellosis and the frequency of musculoskeletal system involvement varies between 2% and 53%. Multifocal spinal involvement is rare. Here, it was aimed to present our case with brucellar spondylodiscitis involving the thoracic and lumbar regions simultaneously. MRI is a useful imaging method in the diagnosis of multifocal spinal infection caused by brucellosis. Especially in endemic regions, at least two serological tests should be used in the diagnosis of brucellosis. Brucellosis should be absolutely kept in mind for the differential diagnosis of the lderly patients with complaint of longstanding thoracic and back pain in the regions where brucellosis is endemic. J Microbiol Infect Dis 2015;5(3: 129-132

  17. A case of exorbitism in association with Wegener′s granulomatosis with renal involvement

    Directory of Open Access Journals (Sweden)

    S Beji

    2012-01-01

    Full Text Available Wegener′s granulomatosis (WG is a necrotizing granulomatous vasculitis invol-ving the nose, paranasal sinuses, lungs, and kidneys. Ocular involvement can occur in about 50% of cases. There are very few reports of WG with orbital inflammation and exorbitism. We report a case of a female patient who presented with exorbitism related to orbital inflammation secondary to WG, with renal involvement. A 29-year-old woman with a previous history of recurrent pan-sinusitis presented with bilateral exophthalmos and renal failure with rapidly progressive glo-merulonephritis. Computed tomography showed extensive bilateral soft tissue in the retro-orbital area. Immunologic tests showed the presence of type-C anti-neutrophil cytoplasmic antibodies and renal biopsy revealed pauci immune crescentic glomerulonephritis. The patient was treated with corticosteroids and pulses of cyclophosphamide followed by azathioprine and trimethoprim-sulfamethoxazole. After a follow-up of 10 months, the renal outcome was favorable with improvement of renal function but there was persistence of exorbitism and loss of visual function. Our case suggests that WG should be considered in the differential diagnosis of persistent bila-teral exophthalmos. Prompt recognition of this early manifestation is important for the institution of early treatment.

  18. A case of exorbitism in association with Wegener's granulomatosis with renal involvement.

    Science.gov (United States)

    Beji, S; Fatma, L Ben; Chebbi, A; Rais, L; Krid, M; Smaoui, W; Maiz, H Ben; Zouaghi, K; Moussa, F Ben

    2012-03-01

    Wegener's granulomatosis (WG) is a necrotizing granulomatous vasculitis involving the nose, paranasal sinuses, lungs, and kidneys. Ocular involvement can occur in about 50% of cases. There are very few reports of WG with orbital inflammation and exorbitism. We report a case of a female patient who presented with exorbitism related to orbital inflammation secondary to WG, with renal involvement. A 29-year-old woman with a previous history of recurrent pan-sinusitis presented with bilateral exophthalmos and renal failure with rapidly progressive glomerulonephritis. Computed tomography showed extensive bilateral soft tissue in the retro-orbital area. Immunologic tests showed the presence of type-C anti-neutrophil cytoplasmic antibodies and renal biopsy revealed pauci immune crescentic glomerulonephritis. The patient was treated with corticosteroids and pulses of cyclophosphamide followed by azathioprine and trimethoprim-sulfamethoxazole. After a follow-up of 10 months, the renal outcome was favorable with improvement of renal function but there was persistence of exorbitism and loss of visual function. Our case suggests that WG should be considered in the differential diagnosis of persistent bilateral exophthalmos. Prompt recognition of this early manifestation is important for the institution of early treatment. PMID:22382229

  19. On Motivating Customer Involvement in Service Innovation--Theory,Practice Implications and Case Study%顾客参与服务创新的激励问题--理论、实践启示及案例分析

    Institute of Scientific and Technical Information of China (English)

    范秀成; 王静

    2014-01-01

    服务创新是促进经济发展与增强企业竞争力的驱动力,而顾客在服务创新过程中扮演着十分重要的角色,了解和满足顾客需求已经成为服务创新一个重要的影响因素。随着顾客越来越广泛地参与到创新过程中,企业需要科学、合理地管理顾客参与,其中对顾客参与激励的管理问题尤为突出。借鉴内/外在动机理论,企业应挑选对服务创新具有较强内在参与动机的顾客参与并给予奖励,建立即时、有效的反馈机制,来自企业和其他顾客群体的社会认可及创新平台体验等是保持顾客参与积极性的手段,且这种激励不应限制或损害顾客参与的内在动机,不应降低顾客的创造力水平。借鉴机制设计理论思路,企业可设计相应的激励机制,使顾客群体能够感受到自己的创新努力得到保护和奖赏,迸发出最大的积极性和创造力,进而在参与服务创新时积极主动地创造有价值、新颖的服务产品。%Service innovation is a driving force in promoting economic development and strengthening firm-competency. Customers play the important role during the process of service innovation;understanding and satisfying customers demand has become an important influencing factor for service innovation. With customers increasingly involved into service innovation,the enterprises should scientifically and rationally manage customer participation,especially the incentive problems. Drawing on the theory of intrinsic and extrinsic motivation,the enterprises should choose customers with strong motivation of participation and grant them with rewards;timely and effective feedback system,recognition from enterprises and other customer groups,and the experience on innovation platform are all the incentive means for the enterprises to maintain customer motivation of participation. And all these incentives should not limit or hurt the intrinsic motivation of

  20. Severe Rhabdomyolysis without Systemic Involvement: A Rare Case of Idiopathic Eosinophilic Polymyositis

    Directory of Open Access Journals (Sweden)

    Ayesha Farooq

    2015-01-01

    Full Text Available Introduction. Eosinophilic polymyositis (EPM is a rare cause of rhabdomyolysis characterized by eosinophilic infiltrates in the muscle. We describe the case of a young patient with eosinophilic polymyositis causing isolated severe rhabdomyolysis without systemic involvement. Case Presentation. A 22-year-old Haitian female with no past medical history presented with progressive generalized muscle aches without precipitating factors. Examination of the extremities revealed diffuse muscle tenderness. Laboratory findings demonstrated peripheral eosinophilia and high creatinine phosphokinase (CPK and transaminase levels. Workup for the common causes of rhabdomyolysis were negative. Her CPK continued to rise to greater than 100,000 units/L so a muscle biopsy was performed which showed widespread eosinophilic infiltrate consistent with eosinophilic polymyositis. She was started on high dose systemic corticosteroids with improvement of her symptoms, eosinophilia, and CPK level. Discussion. This case illustrates a systematic workup of rhabdomyolysis in the presence of peripheral eosinophilia. Many differential diagnoses must be considered before establishing a diagnosis of idiopathic eosinophilic polymyositis. To our knowledge, our case of eosinophilic polymyositis is unique as it presented with severe rhabdomyolysis without another organ involvement. Clinicians should maintain a high index of suspicion for this physically debilitating disease to aid in prompt diagnosis.

  1. Maternal Death Due to Placenta Percreta with Bladder Involvement: A Case Report

    Directory of Open Access Journals (Sweden)

    Sedigheh Ayati M.D.

    2011-06-01

    Full Text Available Background: Placenta accreta is a life-threatening complication after previous cesarean delivery. The aim of this case report is to present a case of placenta percreta with bladder involvement and subsequent maternal death.Case presentation: The patient was a 37-year old who had an unwanted pregnancy due to tubectomy failure two years afterwards. She was hospitalized at 26th and 30th week of gestation because of gross hematuria. Sonography reported placenta previa. Cesarean section was performed at 34th gestational week. Due to severe hemorrhage, hysterectomy with resection of some part of the bladder was done. Died at the operating room after four hours of severe uncontrollable hemorrhage. Conclusion: The increasing prevalence of different forms of placenta accreta is the result of the ever-increasing rate of cesarean deliveries. One of the strategies to prevent this catastrophic obstetric complication is decreasing the number of cesarean deliveries without appropriate indications.

  2. Vocabulary Acquisition and Task Effectiveness in Involvement Load Hypothesis: A case in Iran

    Directory of Open Access Journals (Sweden)

    Hassan Soleimani

    2015-09-01

    Full Text Available Involvement load hypothesis as a cognitive construct states that tasks with higher involvements yield better results in vocabulary retention. This comparison group designed study examined the immediate and delayed effects of tasks with different involvements in involvement load hypothesis (Laufer & Hulstijn, 2001. Applying a version of Nelson Proficiency Test as a homogenizing exclusion criterion, 33 low proficiency Iranian EFL learners were randomly assigned to three experimental groups: blank-filling, sentence making, and reading comprehension. The results of ANOVA and Kruskal-Wallis tests supported task-induced involvement in immediate posttest since the sentence making task (M=5.72 yielded better results in comparison with the other two blank-filling (M=5.45 and reading comprehension (M=3.18 tasks. Nevertheless, sentence making and blank-filling tasks of which the involvements were somehow similar did not yield significant superiority to each other. It is inferred that tasks with nearer involvements yield somehow similar results in vocabulary acquisition.Keywords: task-induced involvement, immediate effect, delayed effect, vocabulary retention, evaluation

  3. Case Studies in Sports Nutrition.

    Science.gov (United States)

    Clark, Nancy

    1988-01-01

    This article presents case studies of two athletes who wanted to affect a change in their body weight in order to enhance athletic performance. Each athlete's problem and the nutrition approach used to solve it are discussed. Caloric values of fast foods are listed. (JL)

  4. The reflexive case study method

    DEFF Research Database (Denmark)

    Rittenhofer, Iris

    2015-01-01

    This paper extends the international business research on small to medium-sized enterprises (SME) at the nexus of globalization. Based on a conceptual synthesis across disciplines and theoretical perspectives, it offers management research a reflexive method for case study research of postnational...

  5. Unexplained False Negative Results in Noninvasive Prenatal Testing : Two Cases Involving Trisomies 13 and 18

    NARCIS (Netherlands)

    Hochstenbach, R; Page-Christiaens, G C M L; van Oppen, A C C; Lichtenbelt, K D; van Harssel, J J T; Brouwer, T; Manten, G T R; van Zon, P; Elferink, M; Kusters, K; Akkermans, O; Ploos van Amstel, J K; Schuring-Blom, G H

    2015-01-01

    Noninvasive prenatal testing (NIPT) validation studies show high sensitivity and specificity for detection of trisomies 13, 18, and 21. False negative cases have rarely been reported. We describe a false negative case of trisomy 13 and another of trisomy 18 in which NIPT was commercially marketed di

  6. Patient Involvement in Safe Delivery: A Qualitative Study

    Science.gov (United States)

    Olfati, Forozun; Asefzadeh, Saeid; Changizi, Nasrin; Keramat, Afsaneh; Yunesian, Masud

    2016-01-01

    Introduction: Patient involvement in safe delivery planning is considered important yet not widely practiced. The present study aimed at identifythe factors that affect patient involvementin safe delivery, as recommended by parturient women. Methods: This study was part of a qualitative research conducted by content analysis method and purposive sampling in 2013. The data were collected through 63 semi-structured interviews in4 hospitalsand analyzed using thematic content analysis. The participants in this research were women before discharge and after delivery. Findings were analyzed using Colaizzi’s method. Results: Four categories of factors that could affect patient involvement in safe delivery emerged from our analysis: patient-related (true and false beliefs, literacy, privacy, respect for patient), illness-related (pain, type of delivery, patient safety incidents), health care professional-relatedand task-related factors (behavior, monitoring &training), health care setting-related (financial aspects, facilities). Conclusion More research is needed to explore the factors affecting the participation of mothers. It is therefore, recommended to: 1) take notice of mother education, their husbands, midwives and specialists; 2) provide pregnant women with insurance coverage from the outset of pregnancy, especially during prenatal period; 3) form a labor pain committee consisting of midwives, obstetricians, and anesthesiologists in order to identify the preferred painless labor methods based on the existing facilities and conditions, 4) carry out research on observing patients’ privacy and dignity; 5) pay more attention on the factors affecting cesarean. PMID:26755469

  7. Factors Associated with Involvement in Bullying: A Study in Nicaragua

    Directory of Open Access Journals (Sweden)

    Eva M. Romera

    2011-07-01

    Full Text Available School bullying is one of the main problems affecting the quality of peer relationships in schools and in general the coexistence. At European level, there are scientific findings that indicate its nature, characteristics and factors related to its involvement. However, in poor and developing countries, where the problem is more serious, there is a high degree of awareness on this matter. The present study aimed to identify what factors may be influencing the occurrence of bullying in a representative sample of primary schools in the Nicaraguan capital. For this propose, 3042 students from Managua and its metropolitan area were explored with instruments comparable to those used in Europe. A multinomial logistic regression analysis indicated that being a boy, to show antisocial behaviors and attitudes and contact with drugs were the three factors most related with the role of aggressor, as well as negative relationships had a significant influence on involvement in this phenomenon, either as a victim, aggressor or victimized aggressor. Results are discussed in relation to the profiles of aggressor and victim of bullying in international studies focusing on differences in developed countries.

  8. An unusual presentation of brucellosis, involving multiple organ systems, with low agglutinating titers: a case report

    Directory of Open Access Journals (Sweden)

    Khorvash Farzin

    2007-07-01

    Full Text Available Abstract Background Brucellosis is a multi-system disease that may present with a broad spectrum of clinical manifestations. While hepatic involvement in brucellosis is not rare, it may rarely involve the kidney or display with cardiac manifestations. Central nervous system involvement in brucellosis sometimes can cause demyelinating syndromes. Here we present a case of brucella hepatitis, myocarditis, acute disseminated encephalomyelitis, and renal failure. Case presentation A 26-year-old man presented with fever, ataxia, and dysarthria. He was a shepherd and gave a history of low grade fever, chilly sensation, cold sweating, loss of appetite, arthralgia and 10 Kg weight loss during the previous 3 months. He had a body temperature of 39°C at the time of admission. On laboratory tests he had elevated level of liver enzymes, blood urea nitrogen, Creatinine, Creatine phosphokinase (MB, and moderate proteinuria. He also had abnormal echocardiography and brain MRI. Enzyme-linked immunosorbent assay for IgG and IgM was negative. Standard tube agglutination test (STAT and 2-mercaptoethanol (2-ME titers were 1:80 and 1:40 respectively. Finally he was diagnosed with brucellosis by positive blood culture and the polymerase chain reaction for Brucella mellitensis. Conclusion In endemic areas clinicians should consider brucellosis in any unusual presentation involving multiple organ systems, even if serology is inconclusive. In endemic areas low STAT and 2-ME titers should be considered as an indication of brucellosis and in these cases additional testing is recommended to rule out brucellosis.

  9. Systemic sarcoidosis with bone marrow involvement responding to therapy with adalimumab: a case report

    Directory of Open Access Journals (Sweden)

    Patel Supen R

    2009-07-01

    Full Text Available Abstract Introduction Sarcoidosis is an inflammatory disorder characterized by the presence of non-caseating granulomas in affected organs. The presence of CD4-positive T lymphocytes and macrophages in affected organs suggests an ongoing immune response. Systemic corticosteroids remain the mainstay of treatment, but therapy is often limited by adverse effects. This is the first report of the use of adalimumab (HUMIRA®, Abbott Laboratories, North Chicago, IL, USA, an anti-tumor necrosis factor monoclonal antibody, in a patient with systemic sarcoidosis with bone marrow involvement. Case presentation A 42-year-old African-American man with a medical history significant for hypertension and diabetes mellitus presented with anemia and thrombocytopenia of two months duration. The patient underwent physical examination, bone marrow aspiration and biopsy, chest X-ray, acid-fast bacilli stain, computed tomography with contrast, and additional laboratory tests. He was diagnosed with systemic sarcoidosis with splenomegaly and bone marrow involvement. Drug therapy included prednisone, which had to be discontinued owing to adverse effects, and adalimumab. Conclusion This is the first report describing the use of adalimumab in a patient with systemic sarcoidosis with bone marrow involvement. Tumor necrosis factor antagonism with adalimumab was efficacious and well-tolerated in this patient and may be considered as a treatment option for similar cases.

  10. Ombuds’ corner: Is the number of cases involving women related to their percentage in an organization?

    CERN Multimedia

    Vincent Vuillemin

    2013-01-01

    Over the past two years, the Ombuds has seen double the number of cases involving women staff members compared to those involving men, relative to their populations. Two questions can thus be asked: is that a general phenomenon also seen in other organizations? Or is it related to the under-representation of women, namely is this a common situation in organizations with fewer women than men? If so, the Ombuds should notice different statistics in organizations where the number of women and men is comparable.   To answer these questions, several annual reports from international organizations have been analysed. The names of these organizations are kept confidential, as the reports are not public. Relation between the percentage of cases involving women and their percentage in an Organization. The circled data point is CERN’s. The results can be seen in this graph (right), limited solely by the number of Organizations for which such data is available. Note that if the ...

  11. Psychological factors involved in prurigo nodularis: A pilot study.

    Science.gov (United States)

    Dazzi, Carla; Erma, Daniela; Piccinno, Roberta; Veraldi, Stefano; Caccialanza, Massimo

    2011-08-01

    Emotional stresses and psychological disorders seem to be concurrent factors in some cases of prurigo nodularis (PN), a chronic skin condition with a difficult therapeutic approach. In order to improve the therapeutic strategies, we performed a psychometric study on 20 patients affected by generalized and histological proven PN. Specific questionnaires were employed to examine the hypotheses (General Health Questionnaire, State Trait Anxiety Inventory - form Y, Beck Depression Inventory-II, and Eysenck Personality Questionnaire). The results show that symptoms of anxiety and depression associated with PN are more severe than in the control group and that some specific traits of personality are more frequently represented in such subjects. The results of our study represent a first attempt to analyze the psychological problems and the personality dimensions which seem to characterize PN patients. Such evidence supports the importance of a psychological approach in the clinical management of PN, which should always include psychological assessment and treatment together with the other therapeutic options.

  12. A clinico-pathological analysis of seventeen cases of non-Hodgkin's lymphoma involving the orbit

    Energy Technology Data Exchange (ETDEWEB)

    Liang, R.; Loke, S.L.; Chiu, E. (University of Hong Kong, Queen Mary Hospital, Pokfulam (Hong Kong). Dept. of Medicine University of Hong Kong, Queen Mary Hospital, Pokfulam (Hong Kong). Dept. of Pathology)

    1991-01-01

    Seventeen patients with non-Hodgkin's lymphoma involving the orbit were studied. There were 12 males and 5 females and their median age was 53 years. Three cases were classified as stage I, two as stage II and 12 as stage IV. The histology was small lymphocytic type in 4 of the 5 stage I and II cases, and immunophenotyping, confirming their B-cell origin, was performed in two of these cases. All stage I and II patients responded favourably to local radiotherapy alone. The 12 stage IV patients had a marked male predominance and more commonly an intermediate grade histology and T-immunophenotype. Several of the orbital lesions seemed to represent extension of nasal lymphomas. The stage IV patients had a poorer survival than the stage I and II patients but the difference was not statistically significant, probably due to the small number of patients. (orig.).

  13. CT and MR findings of langerhans cell histiocytois involving the spleen: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Pyun, Hae Wook; Kim, Mee Eun; Kim, Jang Ho [Fatima Hospital, Taegu (Korea, Republic of)

    2002-02-01

    Langerhans cell histiocytosis (LCH) is systemic disease resulting from the proliferation and dissemination of abnormal histiocytic cells of the Langerhans cell system. Common sites of involvement include the skin, bone, bone marrow, lung, lymph nodes and central nervous system, and the condition manifests in variety of ways. We present the CT and MR findings of a case of LCH involving the spleen, an organ invloved relatively rarely. Post-contrast CT revealed multiple hypodense nodules. T1-weighted MR images of the spleen depicted no definitive lesion, but T2-weighted images showed abnormal low signals scattered throughout this organ. In addition, post-contrast, fat-saturated T1-weighted MR images lesions showed multiple, low-signal-intensity lesions.

  14. CT and MR findings of langerhans cell histiocytois involving the spleen: a case report

    International Nuclear Information System (INIS)

    Langerhans cell histiocytosis (LCH) is systemic disease resulting from the proliferation and dissemination of abnormal histiocytic cells of the Langerhans cell system. Common sites of involvement include the skin, bone, bone marrow, lung, lymph nodes and central nervous system, and the condition manifests in variety of ways. We present the CT and MR findings of a case of LCH involving the spleen, an organ invloved relatively rarely. Post-contrast CT revealed multiple hypodense nodules. T1-weighted MR images of the spleen depicted no definitive lesion, but T2-weighted images showed abnormal low signals scattered throughout this organ. In addition, post-contrast, fat-saturated T1-weighted MR images lesions showed multiple, low-signal-intensity lesions

  15. 22 CFR 99.2 - Reporting requirements for adoption cases involving children emigrating from the United States.

    Science.gov (United States)

    2010-04-01

    ... authority, or other adoption service provider providing adoption services in a case involving the emigration... emigration of a child from the United States to a foreign country: (1) Name, date of birth of child, and... within 30 days of occurrence: (1) Date case determined to involve emigration from the United...

  16. 36 CFR Appendix A to Part 800 - Criteria for Council Involvement in Reviewing Individual section 106 Cases

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Criteria for Council Involvement in Reviewing Individual section 106 Cases A Appendix A to Part 800 Parks, Forests, and Public... Appendix A to Part 800—Criteria for Council Involvement in Reviewing Individual section 106 Cases...

  17. Dental trauma involving root fracture and periodontal ligament injury: a 10-year retrospective study

    OpenAIRE

    Sônia Regina Panzarini; Denise Pedrini; Wilson Roberto Poi; Celso Koogi Sonoda; Daniela Atili Brandini; José Carlos Monteiro de Castro

    2008-01-01

    The purpose of this retrospective study was to analyze the cases of traumatic dental injuries involving root fracture and/or periodontal ligament injury (except avulsion) treated at the Discipline of Integrated Clinic, School of Dentistry of Araçatuba, São Paulo State University (UNESP), Brazil, from January 1992 to December 2002. Clinical and radiographic records from 161 patients with 287 traumatized teeth that had sustained root fracture and/or injuries to the periodontal ligament were exa...

  18. Pulmonary hyalinizing granuloma with laryngeal and subcutaneous involvement: report of a case successfully treated with glucocorticoids.

    Science.gov (United States)

    Shinohara, Takeshi; Kaneko, Takeshi; Miyazawa, Naoki; Nakatani, Yukio; Nishiyama, Harumi; Shoji, Akira; Ishigatsubo, Yoshiaki

    2004-01-01

    We report a case of pulmonary hyalinizing granuloma (PHG) with laryngeal and subcutaneous involvement. A 43-year-old man was admitted to our hospital for assessment of hoarseness. Cervical and chest computed tomography, respectively, revealed a laryngeal tumor and two pulmonary masses. Specimens obtained from the pulmonary masses were compatible with PHG. The histopathology of biopsy specimens from both the laryngeal tumor and a subcutaneous tumor resembled that of the resected lung masses. Although there is no established treatment for PHG, the laryngeal tumor was diminished and all other lesions disappeared with glucocorticoid treatment. PMID:14964583

  19. Collagenous ileitis: a study of 13 cases.

    Science.gov (United States)

    O'Brien, Blake Hugh; McClymont, Kelly; Brown, Ian

    2011-08-01

    Collagenous ileitis (CI), characterized by subepithelial collagen deposition in the terminal ileum, is an uncommon condition. The few cases reported to date have been associated with collagenous colitis (CC) or lymphocytic colitis. Thirteen cases of CI retrieved over a 9-year period were retrospectively studied. There were 7 female and 6 male patients, with an age range of 39 to 72 years (mean, 64 y). Two groups were identified: (1) CI associated with collagenous or lymphocytic disease elsewhere in the gastrointestinal tract and (2) CI as an isolated process. Diarrhea was the presenting symptom in 11 cases. Most patients had no regular medication use. Subepithelial collagen thickness ranged from 15 to 100 μm (mean, 32 μm) and involved 5% to 80% of the subepithelial region of the submitted biopsies. Six cases had >25 intraepithelial lymphocytes (IELs)/100 epithelial cells, and villous blunting was observed in 11 cases. Chronic inflammation of the lamina propria was present in 9 cases, and focal neutrophil infiltration was identified in 3 cases. In biopsies taken from other sites, 7 of 13 colonic biopsies showed CC, 4 of 9 gastric biopsies showed collagenous gastritis, and 2 of 10 duodenal biopsies were abnormal with collagenous sprue (n=1) and partial villous atrophy and increased IELs (n=1) (both celiac disease related). Resolution of the subepithelial collagen deposition was found in the 1 case in which follow-up of terminal ileal biopsies were taken. There was partial or complete resolution of symptoms in 6 of 9 patients for whom follow-up information was available. PMID:21716082

  20. Malignant otitis externa with bilateral cranial nerve involvement: Report of a unique case

    Directory of Open Access Journals (Sweden)

    Somnath Saha

    2013-01-01

    Full Text Available Malignant otitis externa is an inflammatory condition caused by pseudomonas infection usually in the elderly diabetics, or an immunosuppressive condition that presents with diffuse otitis externa along with excruciating pain and granulations tissue in the external auditory meatus. Facial paralysis is common along with occasional involvement of other cranial nerves. Case report describing a patient of malignant otitis externa who presented to a tertiary referral hospital of eastern India. This patient had ipsilateral facial and tenth cranial nerve paralysis along with delayed-onset contralateral sixth and twelfth cranial nerve palsy. The patient was treated initially with intravenous anti-pseudomonal antibody followed by tympanic platectomy, facial nerve decompression and medialisation thyroplasty. The contralateral cranial nerve palsy was managed conservatively with partial recovery of function. Malignant otitis externa, though a common disease, may occasionally present with uncommon or unexplained presentations. The management of these cases should be prompt and aggressive and specifically address each of the debilitating complications.

  1. Atypical Vascular Involvement in a Case of Behçet's Disease

    Directory of Open Access Journals (Sweden)

    Alejandro Rodríguez Morata

    2012-01-01

    Full Text Available Introduction. Behçet's disease (BD is a form of vasculitis of unknown etiology which is rare in our environment. It is characterized by a variety of clinical manifestations and usually affects young adults. Recurrent oral and genital ulcers are a characteristic and extremely frequent symptom, but mortality is linked with more significant symptoms such as aortic pseudoaneurysm, pulmonary pseudoaneurysm, and cerebral venous thrombosis. Patient and Method. We present a case of a young male with atypical BD and severe polyvascular involvement (previous cerebral venous thrombosis and current peripheral venous thrombosis, acute ischemia, and peripheral arterial pseudoaneurysm who required urgent surgical intervention due to a symptomatic external iliac pseudoaneurysm. Result. The pseudoaneurysm was successfully treated, we performed an iliofemoral bypass, and we treated it with steroids and immunosuppressive therapy. Conclusions. These rare clinical manifestations highlight the importance of considering BD in young patients, even in usual cases of vascular intervention, whether arterial or venous in nature.

  2. Unraveling phonological conspiracies: A case study.

    Science.gov (United States)

    Dinnsen, Daniel A; Gierut, Judith A; Morrisette, Michele L; Rose, Darcy E

    2014-01-01

    This paper focuses on three seemingly unrelated error patterns in the sound system of a child with a phonological delay, Child 218 (male, age 4 years 6 months) and ascribes those error patterns to a larger conspiracy to eliminate fricatives from the phonetic inventory. Employing Optimality Theory for its advantages in characterizing conspiracies, our analysis offers a unified account of the observed repairs. The contextual restrictions on those repairs are, moreover, attributed to early developmental prominence effects, which are independently manifested in another error pattern involving rhotic consonants. Comparisons are made with a published case study involving a different implementation of the same conspiracy, the intent being to disambiguate the force behind certain error patterns. The clinical implications of the account are also considered. PMID:25000372

  3. A case study of Impetigo

    Directory of Open Access Journals (Sweden)

    Mansouri P

    1993-05-01

    Full Text Available This is a report of a case study on 234 patients with impetigo who referred to Razi Dermatology Hospital from April to November, 1989. Treatment was started immediately after obtaining direct smear and performing culture and antibiotic sensitivity test. The most common organism responsible for impetigo was the coagulase-positive staphylococcus (71%. In 13.7% of the cases, the coagulase-negative staphylococcus was grown on culture media, but none of the cultures showed streptococcus as the main organism. Treatment was started with oral penicillin V, oral erythromycin, benzathine penicillin G injection, oral cephalexin, and topical fuccidin. Clinical and bacteriological evaluation after 3-7 days showed that it is preferable to use oral cephalexin instead of other protocols such as oral erythromycin, which has previously been the drug of choice for impetigo. In addition, topical fuccidin with a 75% curative rate was the first drug for treatment, with the same effect as the oral cephalexin

  4. Outage management: A case study

    International Nuclear Information System (INIS)

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study

  5. Outage management: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Barriere, M.T. (Brookhaven National Lab., Upton, NY (United States)); Roberts, K.H. (California Univ., Berkeley, CA (United States). Walter A. Haas School of Business)

    1992-01-01

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study.

  6. Outage management: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Barriere, M.T. [Brookhaven National Lab., Upton, NY (United States); Roberts, K.H. [California Univ., Berkeley, CA (United States). Walter A. Haas School of Business

    1992-09-01

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission`s (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study.

  7. Bowel perforation from occult ileal involvement after diagnosis in a case of primary mediastinal large B-cell lymphoma.

    Science.gov (United States)

    De Philippis, Chiara; Di Chio, Maria Chiara; Sabattini, Elena; Bolli, Niccolo

    2016-01-01

    Primary mediastinal large B-cell lymphoma (PMBCL) is confined to the mediastinum or contiguous nodal areas in most cases. Extramediastinal and abdominal involvement, especially at diagnosis, is extremely rare. Our case describes the first case of histologically proven ileal involvement of PMBCL at diagnosis that led to ileal perforation. Positron emission tomography CT could increase the sensitivity of staging by detecting unusual sites of disease localisation, and could impact clinical management. PMID:27417993

  8. Herpesvirus-associated central and peripheral nervous system involvement: two clinical cases

    Directory of Open Access Journals (Sweden)

    T. E. Popova

    2015-01-01

    Full Text Available Herpesviruses can directly affect the structure of the nervous system, resulting in encephalitis, and also induce immune-mediated disorders of the peripheral nervous system as sensory-predominant chronic inflammatory demyelinating polyneuropathy (CIDP. Patients with immunodeficiency may simultaneously develop two pathological processes, determining the severity of the condition. Parainfectious limbic encephalitis (PILE associated with viruses from the family Herpes viridae is a form of chronic herpes encephalitis, which is characterized by dysfunction of the limbic system and by a long-term course with exacerbations. CIDP is a dysimmune disease leasing to peripheral nervous system involvement, which belongs to a class of myelinopathies. The paper describes two clinical cases of a concurrence of chronic PILE and CIDP in middle-aged men who have symptomatic status epilepticus and iatrogenic complications. It characterizes difficulties in diagnosis and the clinical features of chronic herpes infection involving the central and peripheral nervous systems. The given clinical cases suggest that not only neurologistsand epileptologists, but also resuscitation specialists and ngiosurgeons should be particularly alert to the pathology in question.

  9. Vitiligo: A study of 120 cases

    Directory of Open Access Journals (Sweden)

    Kar P

    2001-11-01

    Full Text Available Vitiligo is a common pignientary disorder and of major social and cosmetic concern in India. Purpose of the study was to find out age at onset and sex incidence in vitiligo, role of hereditary factors and associations with other diseases. 120 self reporting vitiligo patients attending out patient department of a service hospital were selected for the study and this data was analysed. In the present series out of 120 cases 62 (51.6% were males and 58(48.35%were females. There was practically no difference in sex incidence. The lowest age of onset was two years and the oldest was 65 years. In the majority of patients,52(43.2%, disease started before twenty years of age.8 (6.6% cases gave definite family history of vitiligo. Exposed areas of the body were commonly affected in majority (66.6% of cases. The legs were commonest site of involvement in 60(50% cases. Circunicript type of vitiligo (46.6% was heading the list. Majority of patients (56.6% had multiple lesions. Diabetes mellitus was found in 2 (2.6% patients. Cause of vitiligo is still idiopathic. Hereditary factors hardly play any role in manifestation of vitiligo

  10. Evaluating a Tacit Knowledge Sharing Initiative: A Case Study

    Science.gov (United States)

    Gubbins, Claire; Corrigan, Siobhan; Garavan, Thomas N.; O'Connor, Christy; Leahy, Damien; Long, David; Murphy, Eamonn

    2012-01-01

    Purpose: This paper aims to present a case study illustrating the issues involved in the tacit knowledge conversion process and to determine whether such conversion delivers value to the organisation in terms of business value and return on investment (ROI). Design/methodology/approach: A single-case multiple baseline participants experimental…

  11. Study of Systemic Risk Involved in Mutual Funds

    Science.gov (United States)

    Dash, Kishore C.; Dash, Monika

    Systemic risk, may be defined as the risk that contaminates to the whole system, consisting of many interacting agents that fail one after another. These agents, in an economic context, could be firms, banks, funds, or other financial institutions. Systemic risk is a macroscopic property of a system which emerges due to the nonlinear interaction of agents on a microscopic level. A stock market itself is a system in which there are many sub-systems, like Dowjones, Nifty, Sensex, Nasdaq, Nikkei and other market indices in global perspective. In Indian market, subsystems may be like Sensex, Nifty, BSE200, Bankex, smallcap index, midcap index, S&P CNX 500 and many others. Similarly there are many mutual funds, which have their own portfolio of different stocks, bonds etc. We have attempted to study the systemic risk involved in a fund as a macroscopic object with regard to its microscopic components as different stocks in its portfolio. It is observed that fund managers do manage to reduce the systemic risk just like we take precautions to control the spread of an epidemic.

  12. TEACHER BELIEFS: A CASE STUDY

    Institute of Scientific and Technical Information of China (English)

    HuYijie

    2004-01-01

    In recent years ELT has stressed the role which teachers' beliefs play in shaping what they do in the classroom. But so far as teaching English in China is concerned, we lack empirical insight into the relationship between teachers' beliefs and their classroom practice. With specific reference to the use of English in intensive reading classes, by presenting and discussing data from a case study of a non-native college English teacher,this exploratory qualitative classroom research sheds light on the nature of teachers' beliefs held consciously or unconsciously.Their subsequent change and impact on the classroom will also be reported and discussed.

  13. Pulmonary involvement in systemic sclerosis: An imaging study from Kashmir

    OpenAIRE

    Iffat Hassan; Nuzhatun Nisa; Mudassir Hamid

    2015-01-01

    Background: Systemic sclerosis (SS) is a chronic, multisystem collagen vascular disorder of undefined etiology, whose prognosis and overall survival is determined by visceral especially the lung involvement. Aim: To evaluate the pulmonary involvement in SS by imaging methods. Materials and Methods: Clinical examination, pulmonary function tests, chest X-ray and high resolution computed tomography (HRCT) scans were carried out in a series of 25 patients prospectively over a period of 3 years (...

  14. Using correspondence analysis in multiple case studies

    NARCIS (Netherlands)

    Kienstra, N.H.H.; van der Heijden, P.G.M.

    2015-01-01

    In qualitative research of multiple case studies, Miles and Huberman proposed to summarize the separate cases in a so-called meta-matrix that consists of cases by variables. Yin discusses cross-case synthesis to study this matrix. We propose correspondence analysis (CA) as a useful tool to study thi

  15. Using Correspondence Analysis in Multiple Case Studies

    NARCIS (Netherlands)

    Kienstra, Natascha; van der Heijden, Peter G.M.

    2015-01-01

    In qualitative research of multiple case studies, Miles and Huberman proposed to summarize the separate cases in a so-called meta-matrix that consists of cases by variables. Yin discusses cross-case synthesis to study this matrix. We propose correspondence analysis (CA) as a useful tool to study thi

  16. A parathyroid scintigraphy case study

    Energy Technology Data Exchange (ETDEWEB)

    O' Leary, Desiree [UCD School of Diagnostic Imaging, St Anthony' s Campus, Herbert Avenue, Dublin 4 (Ireland)]. E-mail: desiree.oleary@ucd.ie

    2005-05-01

    Background: There has been much debate concerning the most suitable protocol for parathyroid scintigraphy; the merits of various radiopharmaceuticals versus the correct imaging protocol to visualise both ectopic and anatomically placed adenomas against the various equipment choices have been debated. Aim: To demonstrate, through the use of a case study, the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion. Method: Use is made of Tc99mMIBI, full field chest scintigraphy, a clearly defined imaging protocol and SPECT imaging to locate ectopic parathyroid tissue in a female patient with significant symptoms of parathyroid hyperfunction. Results: A single hyperfunctioning adenoma is located in the pre-carinal area of the mediastinum. Using a radioguided surgical technique the hyperfunctioning tissue is excised and confirmed by histopathology. Conclusion: Whilst a dramatic reduction in patient symptoms was not seen immediately in this patient, the symptoms of the illness have been subsiding since January 2003. This case study demonstrates the necessity of changing imaging protocols for parathyroid scintigraphy where a definitive imaging diagnosis is absent in the face of strong clinical suspicion.

  17. Visceral leishmaniasis with cardiac involvement in a dog: a case report

    Directory of Open Access Journals (Sweden)

    Goicoa Ana

    2009-04-01

    Full Text Available Abstract A dog presented with cutaneous nodules, enlarged lymph nodes and oedema in limbs, face and abdomen. The diagnosis of visceral leishmaniasis was established by identification of Leishmania amastigotes within macrophages from skin and popliteal lymph node biopsies. At necropsy, lesions were found in different organs, but it was particularly striking to observe large areas of pallor in the myocardium. Histological examination revealed an intense chronic inflammatory reaction in many organs, and numerous macrophages were found to contain amastigote forms of Leishmania. The inflammatory reaction was especially severe in the heart, where large areas of the myocardium appeared infiltrated with huge numbers of mononuclear immune cells, causing cardiac muscle atrophy and degeneration. Despite the severe inflammation, the number of parasitized macrophages was low in the myocardium, as revealed by immunohistochemical staining of Leishmania amastigotes. Because cardiac involvement is not usually described in this condition, this dog represents a very rare case of canine visceral leishmaniasis with affection of the myocardium.

  18. Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report

    Directory of Open Access Journals (Sweden)

    Deniz Arslan

    2014-01-01

    Full Text Available Gastric cancer is the 5th most frequent cancer around the world and the 3rd most frequent reason of deaths due to cancer. Every year, about 1 million new cases are taking place, with varying geographical distribution. Gastric cancer is often metastatic to liver, lungs, and bones in hematogenous way, to peripheral lymph nodes in lymphogenous way, and to peripheral tissues in adjacency way, yet bone marrow (BM and cutaneous metastasis are quite seldom. Pancytopenia is a more frequent finding identified in BM metastasis of solid organ cancers, and isolated thrombocytopenia is less often. The human epidermal growth factor 2 (HER-2 is positive in gastric cancer at a rate of 7–34%. Here, we have presented our HER-2 positive gastric cancer incident which presented with BM and cutaneous metastasis, and has no 18F-fluoro-2-deoxi-D-glucose (FDG involvement except bone metastases.

  19. Nodular liver lesions involving multiple myeloma: A case report and literature review

    Institute of Scientific and Technical Information of China (English)

    Xiao-Ning Wu; Xin-Yan Zhao; Ji-Dong Jia

    2009-01-01

    We report a case of a 62-year old woman admitted to our hospital for multiple nodular metastatic liver lesions found by ultrasonography in a regular medical examination. Routine laboratory tests were normal.PET-CT showed multiple bone lesions and nodular liver lesions. Liver biopsy revealed nodular infiltration of multiple myeloma with positive staining of kappa light chain. Further investigation of bone marrow aspiration, immunofixation and immunoelectrophoresis of serum protein, urine test for Bence-Jones protein,β2-microglobulin in serum and urine confirmed the diagnosis. The patient also coinfected with hepatitis C virus (HCV). With six cycles of chemotherapy with VAD schedule, she achieved complete remission. In this report, a literature review of liver lesions involving multiple myeloma is also provided.

  20. A Case of Porokeratosis Showing Different Clinical Patterns of the Disease with Anogenital Involvement

    Directory of Open Access Journals (Sweden)

    Özlem Karabudak

    2008-10-01

    Full Text Available Porokeratosis (PK is a group of cutaneous entities characterized by marginate scaling lesions, histologically showing a column of parakeratotic keratinocytes (cornoid lamella. Various forms are recognized such as porokeratosis of Mibelli (PM, linear porokeratosis, disseminated superficial actinic porokeratosis, punctate parakeratosis. PM should be treated because of the possibility of developing malignant epithelial tumors. We are presenting a 21 year old male patient suffering from PM on the back of the hands, foot, scrotum, oral mucosa and anal region. The histological biopsy specimens showed the characteristic features of porokeratosis. We destroyed the lesions by cryotherapy sessions. Here, we present a case of PM since it is rarely seen as multiple lesions with oral, anal and scrotal involvements altogether. (Turkderm 2008; 42: 97-9

  1. A Case of Erdheim-Chester Disease with Bilateral Orbital Involvement

    Institute of Scientific and Technical Information of China (English)

    Zhongyao Wu; Jianhua Yan; Wende Hong; Yaoxian Yuan; Lijun Dai

    2001-01-01

    Purpose: To describe a case of Erdheim-Chester disease with bilateral orbital involvement.Methods: A 43-year-old female with bilateral proptosis was presented. Its clinical features, image findings, pathological character and therapeutic effect were evaluated.Results: CT demonstrated bilateral, diffuse orbital mass. Histopathologic assessment revealed a diffuse xanthogranulomatous process with clusters of lipidladen histocytes. Numerous Touton giant cells were scattered throughout the lesion. Renal and heart failure happened during a 6-year follow-up period. Long bones roentgenogram demonstrated diffuse symmetrical sclerosis with extensive, lytic lesions. Systemicadministration of corticosteroids, chemotherapy, immunoglobulin and traditional Chinese medicine showed good therapeutic result. Conclusions: An administration of systemic corticosteroids, chemotherapy, immuno- globin and traditional Chinese medicine can control Erdheim-Chester disease. Further exploration of its pathogenesis and collection of useful clinical data are required.

  2. Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report

    Science.gov (United States)

    Arslan, Deniz; Tatlı, Ali Murat; Goksu, Sema Sezgin; Başsorgun, Cumhur İbrahim; Coskun, Hasan Senol; Bozcuk, Hakan; Savaş, Burhan

    2014-01-01

    Gastric cancer is the 5th most frequent cancer around the world and the 3rd most frequent reason of deaths due to cancer. Every year, about 1 million new cases are taking place, with varying geographical distribution. Gastric cancer is often metastatic to liver, lungs, and bones in hematogenous way, to peripheral lymph nodes in lymphogenous way, and to peripheral tissues in adjacency way, yet bone marrow (BM) and cutaneous metastasis are quite seldom. Pancytopenia is a more frequent finding identified in BM metastasis of solid organ cancers, and isolated thrombocytopenia is less often. The human epidermal growth factor 2 (HER-2) is positive in gastric cancer at a rate of 7–34%. Here, we have presented our HER-2 positive gastric cancer incident which presented with BM and cutaneous metastasis, and has no 18F-fluoro-2-deoxi-D-glucose (FDG) involvement except bone metastases. PMID:25045559

  3. A case of primary spinal myoclonus: clinical presentation and possible mechanisms involved

    Directory of Open Access Journals (Sweden)

    Campos Cynthia Resende

    2003-01-01

    Full Text Available Spinal myoclonus is a rare movement disorder characterized by myoclonic involvement of a group of muscles supplied by a few contiguous segments of the spinal cord. Structural lesions are usually the cause, but in primary spinal myoclonus the etiology remains unknown. We present the case of a 26-year-old woman with cervical spinal myoclonus in which both clinical and electromyographic findings pointed to the segment C1-C3 as the origin of the myoclonus. Laboratorial examinations were normal and no structural lesion was found in magnetic resonance imaging (MRI. Botulinum toxin type A was injected in infrahyoid muscles and cervical paraspinal musculature. The patient remained free of symptoms for almost five months. The pathophysiology of spinal myoclonus remains speculative, but there is evidence that various possible mechanisms can be involved: loss of inhibitory function of local dorsal horn interneurons, abnormal hyperactivity of local anterior horn neurons, aberrant local axons re-excitations and loss of inhibition from suprasegmentar descending pathways.

  4. Neuropathology of supercentenarians - four autopsy case studies.

    Science.gov (United States)

    Takao, Masaki; Hirose, Nobuyoshi; Arai, Yasumichi; Mihara, Ban; Mimura, Masaru

    2016-01-01

    Supercentenarians (aged 110 years old or more) are extremely rare in the world population (the number of living supercentenarians is estimated as 47 in the world), and details about their neuropathological information are limited. Based on previous studies, centenarians (aged 100-109 years old) exhibit several types of neuropathological changes, such as Alzheimer's disease and Lewy body disease pathology, primary age-related tauopathy, TDP-43 pathology, and hippocampal sclerosis. In the present study, we provide results from neuropathological analyses of four supercentenarian autopsy cases using conventional and immunohistochemical analysis for neurodegenerative disorders. In particular, we focused on the pathology of Alzheimer's disease and Lewy body disease, as well as the status of hippocampal sclerosis, TDP-43 pathology, aging-related tau astrogliopathy, and cerebrovascular diseases. Three cases were characterized as an "intermediate" level of Alzheimer's disease changes (NIA-AA guideline) and one was characterized as primary age-related tauopathy. TDP-43 deposits were present in the hippocampus in two cases. Neither Lewy body pathology nor hippocampal sclerosis was observed. Aging-related tau astrogliopathy was consistently observed, particularly in the basal forebrain. Small vessel diseases were also present, but they were relatively mild for cerebral amyloid-beta angiopathy and arteriolosclerosis. Although our study involved a small number of cases, the results provide a better understanding about human longevity. Neuropathological alterations associated with aging were mild to moderate in the supercentenarian brain, suggesting that these individuals might have some neuroprotective factors against aging. Future prospective studies and extensive molecular analyses are needed to determine the mechanisms of human longevity. PMID:27590044

  5. Psoriasis beyond the skin surface: a pilot study on the ocular involvement.

    Science.gov (United States)

    Campanati, A; Neri, P; Giuliodori, K; Arapi, I; Carbonari, G; Borioni, E; Herbort, C P; Mariotti, C; Giovannini, A; Offidani, A

    2015-06-01

    The ocular involvement in psoriasis is not a completely well-known problem. The ophthalmologic involvement occurs in about 10 % of patients, particularly in case of arthropathic or pustular psoriasis. Ocular lesions are more common in males, and they often occur during psoriasis exacerbations. Our study aimed to assess the prevalence and type of ocular involvement in psoriasis, by a comparison between psoriasis and healthy subjects, and if/how a 12-week long systemic immunosuppressive therapy is able to modify them. This study involved thirty-two psoriatic patients and thirty-two healthy subjects. Dermatological evaluation was done using Psoriasis Area and Severity Index, Physician Global Assessment, and Dermatology Life Quality Index (PASI, PGA, and DLQI score). Ophthalmological evaluation included ocular surface involvement (Schirmer, Jones, break-up time--BUT, DR-1 camera), retinal pathologies, and ocular surface disease index. Laboratory investigations including the C-reactive protein (CRP) of all the patients were performed. At baseline, the values of Schirmer, Jones, and BUT tests in the patient group were significantly lower compared to controls; moreover, conjunctival hyperemia was more frequent in psoriatic patients than in healthy subjects. Ocular involvement was more prominent in the subset of psoriatic patients with sebo-psoriasis than in general psoriatic population. A statistically significant correlation was found in sebo-psoriasis between PASI and Schirmer, between PASI and Jones, and between PASI and BUT. On the other hand, the results obtained from DR1 camera showed statistically significant difference between psoriatic and sebo-psoriatic patients at the end of the follow-up. After 12 weeks of treatment, the mean values of PASI, PGA, DLQI, CRP, and BUT showed significant changes in psoriatic patients. Our findings suggest a high rate of ocular involvement in psoriatic patients, emphasizing the need of performing periodic ophthalmological

  6. Case Study: A Picture Worth a Thousand Words? Making a Case for Video Case Studies

    Science.gov (United States)

    Pai, Aditi

    2014-01-01

    A picture, they say, is worth a thousand words. If a mere picture is worth a thousand words, how much more are "moving pictures" or videos worth? The author poses this not merely as a rhetorical question, but because she wishes to make a case for using videos in the traditional case study method. She recommends four main approaches of…

  7. STS Case Study Development Support

    Science.gov (United States)

    Rosa de Jesus, Dan A.; Johnson, Grace K.

    2013-01-01

    The Shuttle Case Study Collection (SCSC) has been developed using lessons learned documented by NASA engineers, analysts, and contractors. The SCSC provides educators with a new tool to teach real-world engineering processes with the goal of providing unique educational materials that enhance critical thinking, decision-making and problem-solving skills. During this third phase of the project, responsibilities included: the revision of the Hyper Text Markup Language (HTML) source code to ensure all pages follow World Wide Web Consortium (W3C) standards, and the addition and edition of website content, including text, documents, and images. Basic HTML knowledge was required, as was basic knowledge of photo editing software, and training to learn how to use NASA's Content Management System for website design. The outcome of this project was its release to the public.

  8. Community involvement in obstetric emergency management in rural areas: a case of Rukungiri district, Western Uganda

    Directory of Open Access Journals (Sweden)

    Ogwang Simon

    2012-03-01

    Full Text Available Abstract Background Maternal mortality is a major public health problem worldwide especially in low income countries. Most causes of maternal deaths are due to direct obstetric complications. Maternal mortality ratio remains high in Rukungiri district, western Uganda estimated at 475 per 100,000 live births. The objectives were to identify types of community involvement and examine factors influencing the level of community involvement in the management of obstetric emergencies. Methods We conducted a descriptive study during 2nd to 28th February 2009 in rural Rukungiri district, western Uganda. A total of 448 heads of households, randomly selected from 6/11 (54.5% of sub-counties, 21/42 (50.0% parishes and 32/212 (15.1% villages (clusters, were interviewed. Data were analysed using STATA version 10.0. Results Community pre-emergency support interventions available included community awareness creation (sensitization while interventions undertaken when emergency had occurred included transportation and referring women to health facility. Community support programmes towards health care (obstetric emergencies included establishment of community savings and credit schemes, and insurance schemes. The factors associated with community involvement in obstetric emergency management were community members being employed (AOR = 1.91, 95% CI: 1.02 - 3.54 and rating the quality of maternal health care as good (AOR = 2.22, 95% CI: 1.19 - 4.14. Conclusions Types of community involvement in obstetric emergency management include practices and support programmes. Community involvement in obstetric emergency management is influenced by employment status and perceived quality of health care services. Policies to promote community networks and resource mobilization strategies for health care should be implemented. There is need for promotion of community support initiatives including health insurance schemes and self help associations; further community

  9. A Comparative Study of Involvement and Motivation among Casino Gamblers

    Science.gov (United States)

    Lee, Choong-Ki; Lee, BongKoo; Bernhard, Bo Jason

    2009-01-01

    Objective The purpose of this paper is to investigate three different types of gamblers (which we label "non-problem", "some problem", and "probable pathological gamblers") to determine differences in involvement and motivation, as well as differences in demographic and behavioral variables. Methods The analysis takes advantage of a unique opportunity to sample on-site at a major casino in South Korea, and the resulting purposive sample yielded 180 completed questionnaires in each of the three groups, for a total number of 540. Factor analysis, analysis of variance (ANOVA) and Duncan tests, and Chi-square tests are employed to analyze the data collected from the survey. Results Findings from ANOVA tests indicate that involvement factors of importance/self-expression, pleasure/interest, and centrality derived from the factor analysis were significantly different among these three types of gamblers. The "probable pathological" and "some problem" gamblers were found to have similar degrees of involvement, and higher degrees of involvement than the non-problem gamblers. The tests also reveal that motivational factors of escape, socialization, winning, and exploring scenery were significantly different among these three types of gamblers. When looking at motivations to visit the casino, "probable pathological" gamblers were more likely to seek winning, the "some problem" group appeared to be more likely to seek escape, and the "non-problem" gamblers indicate that their motivations to visit centered around explorations of scenery and culture in the surrounding casino area. Conclusion The tools for exploring motivations and involvements of gambling provide valuable and discerning information about the entire spectrum of gamblers. PMID:20046388

  10. Contextualising case studies in entrepreneurship: A tandem approach to conducting a longitudinal cross-country case study

    DEFF Research Database (Denmark)

    Chetty, S. K.; Partanen, J.; Rasmussen, Erik Stavnsager;

    2014-01-01

    Using predictive and effectuation logics as a framework, this research note explains how case study research was conducted to demonstrate rigour and relevance. The study involves a longitudinal cross-country case study on small and medium-sized firm growth and networks undertaken by research teams...... in three countries (Finland, Denmark and New Zealand) involving 33 firms. This research note outlines the implications of this research and provides valuable guidance and reflections upon opportunities for future research regarding the conduct of contextual studies in entrepreneurship without...

  11. Using Case Studies To Teach Science.

    Science.gov (United States)

    Gabel, Connie

    Using case studies in science instruction develops problem solving and enhances listening and cooperative learning skills. Unlike other disciplines such as law and medicine, the case study method is rarely used in science education to enrich the curriculum. This study investigates the use of content-based case studies as a means of developing…

  12. Catalog of NASA-Related Case Studies

    Data.gov (United States)

    National Aeronautics and Space Administration — The OCKO has developed over 50 case studies to enhance learning at workshops, training, retreats and conferences. Case studies make mission knowledge attractive and...

  13. Case Study of a Participatory Health Promotion Intervention in School

    DEFF Research Database (Denmark)

    Simovska, Venka

    2012-01-01

    study showed that, if given sufficient guidance, children can act as agents of health promoting changes. The main arena for pupils’ influence was the pupils’ council. Pupils were meaningfully involved in two actions, which targeted road safety around the school and a playground for a disadvantaged......In this article I discuss the findings from a case study focusing on processes involving pupils to bring about health promotion changes. The case study is related to a large EU intervention project aiming to promote health and wellbeing among children (4-16 years), ‘Shape Up: a school......-community approach to influencing determinants of healthy and balanced growing up’. Qualitative case study research was carried out in a school in the Netherlands. Data sources included project documents, interviews and observations. Thematic analysis was carried out combining the different data sources. The case...

  14. Renal and perirenal space involvement in acute pancreatitis: An MRI study

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xing Hui, E-mail: lixinghui1005@126.com [Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Zhang, Xiao Ming, E-mail: cjr.zhxm@vip.163.com [Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Ji, Yi Fan, E-mail: 526504036@qq.com [Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Jing, Zong Lin, E-mail: jzl325@163.com [Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Huang, Xiao Hua, E-mail: nc_hxh1966@yahoo.com.cn [Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Yang, Lin, E-mail: linyangmd@163.com [Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China); Zhai, Zhao Hua, E-mail: zhaizhaohuada@163.com [Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000 (China)

    2012-08-15

    Objectives: To study the prevalence and characteristics of renal and perirenal space involvement and its relation to the severity of acute pancreatitis (AP) using MRI. Methods: 115 patients with AP who underwent MRI with the clinical kidney function test were retrospectively analyzed in this study. MRI sequences included conventional and diffusion weighted imaging (DWI) sequences. The renal and perirenal space involvement in AP was noted on MRI. The renal apparent diffusion coefficient (ADC) on DWI was measured for each kidney. The severity of AP on MRI was graded using MR severity index (MRSI). The relationships among the renal and perirenal space involvement on MRI, the renal ADC, MRSI and the results of the kidney function test were analyzed. Results: In the 115 patients with AP, the renal and perirenal space abnormalities detected included renal parenchymal abnormalities (0.8%), abnormalities of the renal collecting system (2.6%), renal vascular abnormalities (1.7%), thickened renal fascia (99%), perirenal stranding (62%) and perirenal fluid collection (40%). The prevalence of perirenal space abnormalities was correlated with the severity of AP based on MRSI (P < 0.05). The renal ADC values were lower in patients with abnormal kidney function than in those without kidney injury (P < 0.05). The prevalence of kidney function abnormalities was 9.4%, 32% and 100% in mild, moderate, and severe AP cases, respectively (P = 0.00). Conclusion: Perirenal space involvement is much more than renal parenchymal involvement in AP. The prevalence of perirenal space involvement in AP on MRI has a positive correlation with the severity of AP according to MRSI.

  15. Renal and perirenal space involvement in acute pancreatitis: An MRI study

    International Nuclear Information System (INIS)

    Objectives: To study the prevalence and characteristics of renal and perirenal space involvement and its relation to the severity of acute pancreatitis (AP) using MRI. Methods: 115 patients with AP who underwent MRI with the clinical kidney function test were retrospectively analyzed in this study. MRI sequences included conventional and diffusion weighted imaging (DWI) sequences. The renal and perirenal space involvement in AP was noted on MRI. The renal apparent diffusion coefficient (ADC) on DWI was measured for each kidney. The severity of AP on MRI was graded using MR severity index (MRSI). The relationships among the renal and perirenal space involvement on MRI, the renal ADC, MRSI and the results of the kidney function test were analyzed. Results: In the 115 patients with AP, the renal and perirenal space abnormalities detected included renal parenchymal abnormalities (0.8%), abnormalities of the renal collecting system (2.6%), renal vascular abnormalities (1.7%), thickened renal fascia (99%), perirenal stranding (62%) and perirenal fluid collection (40%). The prevalence of perirenal space abnormalities was correlated with the severity of AP based on MRSI (P < 0.05). The renal ADC values were lower in patients with abnormal kidney function than in those without kidney injury (P < 0.05). The prevalence of kidney function abnormalities was 9.4%, 32% and 100% in mild, moderate, and severe AP cases, respectively (P = 0.00). Conclusion: Perirenal space involvement is much more than renal parenchymal involvement in AP. The prevalence of perirenal space involvement in AP on MRI has a positive correlation with the severity of AP according to MRSI.

  16. The Faithless Employee: A Case Involving the Legal and Accounting Issues Associated with Employee Theft of Company Funds

    Science.gov (United States)

    Gruber, Robert; Molloy, James

    2005-01-01

    This case explores the areas of public accounting/auditing and business law as they relate to the conduct of an employee who intentionally and unlawfully obtains, and, negotiates for his own benefit, his employer's negotiable instruments (checks). In particular, this case involves an accountant who unlawfully acquired negotiable instruments,…

  17. Central nervous system granulomastous phlebitis with limited extracranial involvement of the heart and lungs: An autopsy case.

    Science.gov (United States)

    Mlakar, Jernej; Zorman, Jerneja Videčnik; Matičič, Mojca; Vrabec, Matej; Alibegović, Armin; Popović, Mara

    2016-02-01

    Primary angiitis of the central nervous system is a rare condition, usually with an insidious onset. There is a wide variety of histological types (granulomatous, lymphocytic or necrotizing vasculitis) and types of vessel involved (arteries, veins or both). Most cases are idiopathic. We describe a first case of idiopathic granulomatous central nervous system phlebitis with additional limited involvement of the heart and lung, exclusively affecting small and medium sized veins in a 22-year-old woman, presenting as a sub acute headache. The reasons for this peculiar limitation of inflammation to the veins and the involvement of the heart and lungs are unknown.

  18. Caregiver Involvement in the Education of Youth in Foster Care: An Exploratory Study

    Science.gov (United States)

    Beisse, Kay; Tyre, Ashli

    2013-01-01

    This study was an exploratory investigation of caregiver involvement in the education of youth in foster care. In this study, foster caregivers reported that they are involved in the education of children in their care and participate in at-home involvement activities more often than at-school involvement activities. Caregivers in this study…

  19. Capturing Cultural Glossaries: Case-study II

    Directory of Open Access Journals (Sweden)

    Matete Madiba

    2011-10-01

    Full Text Available

    ABSTRACT: This case-study attempts to present a brief glossary of Northern Sotho medical terms. It is a follow-up of a similar case-study (Madiba, Mphahlele and Kganyago 2003, which was an attempt to capture and present Northern Sotho cooking terms. Case-study I consists of the names for utensils, ingredients and the processes involved in the preparation of cultural dishes. With both these case-studies, the intention has been to use the opportunities availing themselves for the pres-ervation and valorisation of Northern Sotho, including the extension of its corpora to support national dictionary-making processes. The case-study methodology has been very useful for the purposes of this project and the context within which it was undertaken. It aims to provide a model for the collection and presentation of authentic Northern Sotho terminology which otherwise would hardly have been accessible.

    Keywords: CULTURAL GLOSSARY, INDIGENOUS KNOWLEDGE SYSTEMS, CORPUS, OUTCOMES-BASED EDUCATION, ASSESSMENT CRITERIA, TRADITIONAL MEDICAL TERMS, COMMUNICATIVE APPROACH, STRUCTURAL APPROACH, METONYMY, HANDS-ON ACTIVITIES, TASK-BASED LEARNING

    *****

    OPSOMMING: Die totstandbrenging van kulturele woordversamelings: Ge-vallestudie II. Hierdie gevallestudie probeer om 'n beperkte woordelys van Noord-Sotho- mediese terme aan te bied. Dit is 'n voortsetting van 'n soortgelyke gevallestudie (Madiba, Mpha-hlele en Kganyago 2003 wat 'n poging was om Noord-Sothokookterme te versamel en aan te bied. Gevallestudie I bestaan uit die name van gereedskap, bestanddele, en die prosesse betrokke by die voorbereiding van kulturele geregte. Met altwee hierdie gevallestudies was die bedoeling om die geleenthede te gebruik wat hulleself aanbied vir die bewaring en bestendiging van Noord-Sotho, insluitende die uitbreiding van sy korpora om die nasionale woordeboeksamestellingsprosesse te ondersteun. Die gevallestudiemetodologie was baie nuttig vir die doeleindes van

  20. Cerebral involvement in a patient with Goodpasture's disease due to shortened induction therapy: a case report

    Directory of Open Access Journals (Sweden)

    Preul Christoph

    2009-11-01

    Full Text Available Abstract Introduction Goodpasture's disease is a rare immunological disease with formation of pathognomonic antibodies against renal and pulmonary basement membranes. Cerebral involvement has been reported in several cases in the literature, yet the pathogenetic mechanism is not entirely clear. Case presentation A 21-year-old Caucasian man with Goodpasture's disease and end-stage renal disease presented with two generalized seizures after a period of mild cognitive disturbance. Blood pressure and routine laboratory tests did not exceed the patient's usual values, and examination of cerebrospinal fluid was unremarkable. Cerebral magnetic resonance imaging (MRI revealed multiple cortical and subcortical lesions on fluid-attenuated inversion recovery sequences. Since antiglomerular basement membrane antibodies were found to be positive with high titers, plasmapheresis was started. In addition, cyclophosphamide pulse therapy was given on day 13. Encephalopathy and MRI lesions disappeared during this therapy, and antiglomerular basement membrane antibodies were significantly reduced. Previous immunosuppressive therapy was performed without corticosteroids and terminated early after 3 months. The differential diagnostic considerations were cerebral vasculitis and posterior reversible encephalopathy syndrome. Vasculitis could be seen as an extrarenal manifestation of the underlying disease. Posterior reversible encephalopathy syndrome, on the other hand, can be triggered by immunosuppressive therapy and may appear without a hypertensive crisis. Conclusion A combination of central nervous system symptoms with a positive antiglomerular basement membrane test in a patient with Goodpasture's disease should immediately be treated as an acute exacerbation of the disease with likely cross-reactivity of antibodies with the choroid plexus. In our patient, a discontinuous strategy of immunosuppressive therapy may have favored recurrence of Goodpasture's disease.

  1. Automated cardiopulmonary resuscitation: a case study.

    Science.gov (United States)

    Spiro, Jon; Theodosiou, Maria; Doshi, Sagar

    2014-02-01

    Rates of survival after cardiac arrest are low and correlate with the quality of cardiopulmonary resuscitation (CPR). Devices that deliver automated CPR (A-CPR) can provide sustained and effective chest compressions, which are especially useful during patient transfer and while simultaneous invasive procedures are being performed. The use of such devices can also release members of resuscitation teams for other work. This article presents a case study involving a man with acute myocardial infarction complicated by cardiogenic shock and pulmonary oedema. It describes how ED nursing and medical teams worked together to deliver A-CPR, discusses the use of A-CPR devices in a tertiary cardiac centre, and highlights the advantages of using such devices.

  2. Concentrated photovoltaics, a case study

    Directory of Open Access Journals (Sweden)

    Antonini Piergiorgio

    2014-01-01

    Full Text Available Concentrated Photovoltaics (CPV, once a niche technology, has now reached the maturity and reliability for large scale power generation. Especially in regions where temperatures are very high, the use of high efficiency triple junction solar cells with concentrating optics allows stable energy yield. Thus CPV can be seen as complementary and not in concurrence with silicon photovoltaics. The state of the art, the advantages and limitations of this technology will be shown. Among the main advantages of CPV is the possibility of a much higher energy supply, when compared to silicon photovoltaics, both comparing CPV and silicon with same area or the same installed power. The use of recycled and recyclable materials allows a more environmentally friendly production. The possibility to couple CPV with desalination facilities, energy storage will be analysed. As an example a case study of a CPV installation in Northern Italy is discussed. Here the use of mature technologies, derived from automotive and lighting sectors resulted in a simple and efficient module.

  3. Implementing the Health Promoting School in Denmark: A Case Study

    Science.gov (United States)

    Nordin, Lone Lindegaard

    2016-01-01

    Purpose: The purpose of this paper is to provide insight into teachers' practice in implementing school-based health promotion. Design/methodology/approach: This qualitative research was designed as a multiple case study. The study involved five schools, 233 pupils in the age 12-16 and 23 teachers. The primary data generation method were focus…

  4. Follicular variant of peripheral T cell lymphoma with mediastinal involvement in a child: a case report.

    Science.gov (United States)

    Delas, Audrey; Gaulard, Philippe; Plat, Geneviève; Brousset, Pierre; Laurent, Camille

    2015-03-01

    Peripheral T cell lymphomas are rare in young patients. We report the first case of a follicular variant of peripheral T cell lymphoma not otherwise specified in an 11-year-old boy, who presented with a large mediastinal mass. Microscopic examination of the mediastinal biopsy revealed nodular infiltration of medium- to large-sized atypical lymphocytes. Immunohistochemistry showed expression of follicular helper T cell markers (CD10, PD1, CXCL13, and BCL6) in tumor T cells. Epstein-Barr virus (EBV) was not detected by an in situ hybridization assay for EBV-encoded RNA. Interestingly, fluorescence in situ hybridization detected the presence in the tumor cells of the t(5;9)(q33;q22) translocation, involving ITK and SYK rearrangement. T cell clonality was detected by multiplex PCR analysis of TRG and TRD gene rearrangements. After 4 cycles of systemic chemotherapy, the patient was in complete remission. Although this entity is very rare, our observations show that lymphomas arising from T follicular helper cells may occur in children and that this should be distinguished from other lymphomas, such T-lymphoblastic lymphomas, which require a specific therapeutic approach. PMID:25604350

  5. Traumatic L5 over S1 spondyloptosis without neurological involvement managed nonoperatively: a case report

    Institute of Scientific and Technical Information of China (English)

    Vijay Goni; Nirmal Raj Gopinathan; Uttam Chand Saini; Shashidhar B Kantharajanna

    2013-01-01

    High-grade spondylolisthesis is very rare.We came across a case of high-grade spondylolisthesis at the L5-S1 level in a 32-year-old manual labourer who was hit by a heavy object on his flexed back.The patient presented to us with persistent deformity in the back.He complained of back pain on prolonged standing and after moderate work.Because of that he was unable to return to his work.On clinical examination there was a large step in the lower lumbar region.Detailed neurological evaluation of the lower limbs did not reveal any sensory or motor deficit,neither did bowel or bladder involvement.Radiographic examination showed L5 over S1 traumatic spondyloptosis.CT scan revealed that neural canal was in normal width.MRI confirmed spondyloptosis of L5 over S1 without any compromise of the spinal canal and with normal-looking cauda.Concerning the delayed presentation and no neurological deficit,the patient was managed conservatively after thorough counsel.At 6 months,the patient returned to his work and at the latest follow-up (15 months) he was free from back pain.Conservative means of treatment can lead to satisfactory outcome,especially when the patient has delayed presentation.

  6. Secondary Involvement of the Mandible due to Basal Cell Carcinoma: A Case Report

    Directory of Open Access Journals (Sweden)

    Pegah Mosannen Mozaffary

    2015-05-01

    Full Text Available Basal cell carcinoma (BCC is the most common cutaneous malignancy among Caucasians. Rare examples of aggressive and neglected BCC have been reported. Here we report a unique case of a neglected BCC with significant jaw involvement. A 50-year-old female, referred by an otorhinologist, presented with a large ulcer on her chin, which was extended to her mandibular vestibule. The ulcer was 9×5.5 cm in size, and tissue destruction, necrosis was observed in the central portion, and the mandibular bone was exposed. On intraoral examination, tooth mobility and severe bone loss were evident. Due to the primary cutaneous origin of the lesion, BCC was considered as preliminary diagnosis. Biopsy was performed and diagnosis of BCC was confirmed. The diseased mandibular bone was resected and reconstructed with a surgical plate. The soft tissue defect was reconstructed with deltopectoral flap. The patient refused secondary stage plastic surgery. Although BCC is not a lethal malignancy, if left untreated and neglected, it can result in severe destruction, disfigurement, and even mortality.

  7. The case study of biomaterials and biominerals

    Science.gov (United States)

    Del Hoyo Martínez, Carmen

    2013-04-01

    The teaching of biomaterials as case study by on-line platform , susceptible to develop both individually and in groups, got different objectives proposed by the European Higher Education System, among which include: participate actively in the teaching-learning process by students, interpreting situations, adapt processes and solutions. It also improves oral and written communication, analytical skills and synthesis and also the ability to think critically. Biomaterials have their origin in biominerals. These are solid inorganic compounds of defined structure, consisting of molecular control mechanisms that operate in biological systems. Its main functions are: structural support, a reservoir of essential elements, sensors, mechanical protection and storage of toxic elements. Following the demand of materials compatible with certain functional systems of our body, developed biomaterials. Always meet the condition of biocompatibility. Should be tolerated by the body and do not provoke rejection. This involves a comprehensive study of physiological conditions and the anatomy of the body where a biomaterial has to be implemented. The possibility of generating new materials from biominerals has a major impact in medicine and other fields could reach as geology, construction, crystallography, etc. While the study of these issues is in its infancy today, can be viewed as an impact on the art and future technology. Planning case study that students would prepare its report for discussion in subgroups. Occurs then the pooling of individual analysis, joint case discussion and adoption by the subgroup of a consensual solution to the problem. The teacher as facilitator and coordinator of the final case analysis, sharing leads to group-wide class and said the unanimous decision reached by the students and gives his opinion on the resolution of the case. REFERENCES D.P. Ausubel. Psicología Educativa. Un punto de vista cognoscitivo. Trillas. Ed. 1983. E.W. Eisner. Procesos

  8. Prehospital airway management: A prospective case study.

    Science.gov (United States)

    Wilbers, N E R; Hamaekers, A E W; Jansen, J; Wijering, S C; Thomas, O; Wilbers-van Rens, R; van Zundert, A A J

    2011-01-01

    We conducted a one-year prospective study involving a prehospital Emergency Medical Service in the Netherlands to investigate the incidence of failed or difficult prehospital endotracheal intubation. During the study period the paramedics were asked to fill in a registration questionnaire after every endotracheal intubation. Of the 26,271 patient contacts, 256 endotracheal intubations were performed by paramedics in one year. Endotracheal intubation failed in 12 patients (4.8%). In 12.0% of 249 patients, a Cormack and Lehane grade III laryngoscopy was reported and a grade IV laryngoscopy was reported in 10.4%. The average number of endotracheal intubations per paramedic in one year was 4.2 and varied from zero to a maximum of 12. The median time between arrival on the scene and a positive capnograph was 7 min.38 s in the case of a Cormack and Lehane grade I laryngoscopy and 14 min.58 s in the case of a Cormack and Lehane grade 4 laryngoscopy. The incidence of endotracheal intubations performed by Dutch paramedics in one year was low, but endotracheal intubation was successful in 95.2%, which is comparable with findings in international literature. Early capnography should be used consistently in prehospital airway management. PMID:21612142

  9. Evaluation of brachial plexus fascicles involvement on infraclavicular block: unfixed cadaver study

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Buarque de Gusmão

    2015-06-01

    Full Text Available BACKGROUND AND OBJECTIVES: This study shows how the diffusion of the anesthetic into the sheath occurs through the axillary infraclavicular space and hence proves the efficacy of the anesthetic block of the brachial plexus, and may thereby allow a consolidation of this pathway, with fewer complications, previously attached to the anesthesia. MATERIALS AND METHODS: 33 armpits of adult cadavers were analyzed and unfixed. We injected a solution of neoprene with latex dye in the infraclavicular space, based on the technique advocated by Gusmão et al., and put the corpses in refrigerators for three weeks. Subsequently, the specimens were thawed and dissected, exposing the axillary sheath along its entire length. RESULTS AND DISCUSSION: Was demonstrated involvement of all fasciculus of the plexus in 51.46%. In partial involvement was 30.30%, 18.24% of cases the acrylic was located outside the auxiliary sheath involving no issue. CONCLUSIONS: The results allow us to establish the infraclavicular as an effective and easy way to access plexus brachial, because the solution involved the fascicles in 81.76% partially or totally, when it was injected inside the axillary sheath. We believe that only the use of this pathway access in practice it may demonstrate the efficiency.

  10. Interactive verification of Markov chains: Two distributed protocol case studies

    Directory of Open Access Journals (Sweden)

    Johannes Hölzl

    2012-12-01

    Full Text Available Probabilistic model checkers like PRISM only check probabilistic systems of a fixed size. To guarantee the desired properties for an arbitrary size, mathematical analysis is necessary. We show for two case studies how this can be done in the interactive proof assistant Isabelle/HOL. The first case study is a detailed description of how we verified properties of the ZeroConf protocol, a decentral address allocation protocol. The second case study shows the more involved verification of anonymity properties of the Crowds protocol, an anonymizing protocol.

  11. A HARD CHOICE (CASE STUDY)

    OpenAIRE

    KRAVCHENKO NATALIYA A.; KUZNETSOVA SVETLANA A.

    2014-01-01

    The case describes the problems of strategic choice: a small company successfully working in the engineering market (automation of technological processes) in the electric power industry has to make a decision on its further development in a changing external environment and increased competition. The case was carried out to be used in training programs of different levels within the courses “Strategic Management”, “Innovation Management”, “Strategic Analysis Methods”, “Change Management” whe...

  12. Asymptomatic cerebral involvement in Sjoegren's syndrome: MRI findings of 15 cases

    Energy Technology Data Exchange (ETDEWEB)

    Pierot, L. (Service de Neuroradiologie Charcot, G.H. Pitie-Salpetriere, Paris (France)); Sauve, C. (Service de Neurologie, G.H. Pitie-Salpetriere, Paris (France)); Leger, J.M. (Service de Neurologie, G.H. Pitie-Salpetriere, Paris (France)); Martin, N. (Service de Neuroradiologie Charcot, G.H. Pitie-Salpetriere, Paris (France)); Koeger, A.C. (Service de Rhumatologie, G.H. Pitie-Salpetriere, Paris (France)); Wechsler, B. (Service de Medecine Interne, G.H. Pitie-Salpetriere, Paris (France)); Chiras, J. (Service de Neuroradiologie Charcot, G.H. Pitie-Salpetriere, Paris (France))

    1993-05-01

    Fifteen patients with Sjoegren's syndrome without clinical evidence of central nervous system disease were studied by MRI. Signal abnormalities were observed in 9 (60%). They were always visible on T2-weighted images as small punctale areas of high signal in the basal ganglia and the white mater of the cerebral hemispheres. Abnormalities were less frequently seen on T1-weighted images. Enlargement of cerebral sulci was observed in 6 cases. The specificity and significance of these abnormalities are discussed. (orig.)

  13. Stafne’s bone cavity: An unusual case with involvement of the buccal and lingual mandibular plates

    Science.gov (United States)

    Figueiredo, Rui; Gay-Escoda, Cosme

    2014-01-01

    Lingual mandibular bone defects, also known as Stafne bone cavity (SC), are unilateral asymptomatic radiolucencies, generally seen in the mandibular angle, below the inferior alveolar canal. Although panoramic radiographies normally offer enough information to make a correct diagnosis, additional studies are often required, especially in atypical cases. The present report describes an atypical presentation of a Stafne’s bone cavity in a 78 years-old male patient. In this particular case, an asymptomatic and radiolucid lesion was observed during a routine dental examination. The computed tomography (CT) showed an involvement of both lingual and buccal mandibular plates producing a tunnel-like lesion. No history of mandibular trauma or surgery was refered. An additional magnetic resonance imaging (MRI) was made to discard submandibular gland pathology and to confirm the diagnosis. Since SC is asymptomatic and nonprogressive, a conservative approach based in clinical and radiological follow-ups was considered to be the most suitable treatment option. Key words:Stafne bone cavity, lingual mandibular bone defect, case report. PMID:24596643

  14. STAKEHOLDERS AND APART HOTELS: MULTIPLE CASE STUDY

    Directory of Open Access Journals (Sweden)

    Patrícia Freire Ferreira Oliveira

    2012-09-01

    Full Text Available Means of accommodation involve a wide range of social actors and agents, as well as different business models. Management strategies in this sector have been increasingly important for long-term sustainability and competitiveness of business organizations. This study aims to analyze the interactions between apart-hotels and their stakeholders to foster an improvement of services provided, aligning the interface of strategic management from the point of view of managers and their key stakeholders. It is an exploratory study, with qualitative chacter, along with multiple case studies of the following establishments: Travel Inn, Hotels Slaviero and Etoile george v. Brazilian enterprises, which manage lodging facilities with apart-hotel concepts, combining features that enable comparative analysis of the study. For conceptual understanding, this study was based on literature about stakeholders, taking the work of Freeman (1984 and Freeman et al (2010 as main references. The research was conducted through semi-structured interviews with managers of lodging facilities and their key stakeholders and through direct observation and documentation. We found that not all groups of influence are considered in the planning of service flats. However, the organizations surveyed indicated that the market has realized the importance of the groups that exert influence and are influenced by their goals, and are therefore increasingly alert for integration of such groups in their strategic planning.

  15. Five misunderstandings about case study research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2004-01-01

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...... useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one...... and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without exemplars is an ineffective one. Social science may be strengthened by the execution of more...

  16. Five misunderstandings about Case-study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...... useful for generating hypotheses, while other methods aremore suitable for hypotheses testing and theory building; (4) The case study contains a bias toward verification; and (5) It is often difficult to summarize specific case studies. The article explains and corrects these misunderstandings one by one...... and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and that a discipline without  exemplars is an ineffective one. Social science may be strengthened by the execution of more...

  17. Five Misunderstandings About Case-Study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2006-01-01

    This article examines five common misunderstandings about case-study research: (a) theoretical knowledge is more valuable than practical knowledge; (b) one cannot generalize from a single case, therefore, the single-case study cannot contribute to scientific development; (c) the case study is most...... useful for generating hypotheses, whereas other methods are more suitable for hypotheses testing and theory building; (d) the case study contains a bias toward verification; and (e) it is often difficult to summarize specific case studies. This article explains and corrects these misunderstandings one...... by one and concludes with the Kuhnian insight that a scientific discipline without a large number of thoroughly executed case studies is a discipline without systematic production of exemplars, and a discipline without exemplars is an ineffective one. Social science may be strengthened by the execution...

  18. Transanal rectopexy - twelve case studies

    Directory of Open Access Journals (Sweden)

    Rubens Henrique Oleques Fernandes

    2012-06-01

    Full Text Available OBJECTIVES: This study analyzed the results of transanal rectopexy and showed the benefits of this surgical technique. METHOD: Twelve patients were submitted to rectopexy between 1997 and 2011. The surgical technique used was transanal rectopexy, where the mesorectum was fixed to the sacrum with nonabsorbable suture. Three patients had been submitted to previous surgery, two by the Delorme technique and one by the Thiersch technique. RESULTS: Postoperative hospital stay ranged from 1 to 4 days. One patient (8.3% had intraoperative hematoma, which was treated with local compression and antibiotics. One patient (8.3% had residual mucosal prolapse, which was resected. Prolapse recurrence was seen in one case (8.3%. Improved incontinence occurred in 75% of patients and one patient reported obstructed evacuation in the first month after surgery. No death occurred. CONCLUSION: Transanal rectopexy is a simple, low cost technique, which has shown good efficacy in rectal prolapse control.OBJETIVO: O presente estudo analisou os resultados da retopexia pela via transanal e expôs os benefícios desta técnica cirúrgica. MÉTODO: Doze pacientes com prolapso foram operados no período de 1997 a 2011. A técnica cirúrgica usada foi a retopexia transanal, onde o mesorreto foi fixado ao sacro com fio inabsorvível. Três pacientes tinham cirurgia prévia, dois pela técnica de Delorme e um pela técnica de Thiersch. RESULTADOS: A permanência hospitalar pós-operatória variou de 1- 4 dias. Uma paciente (8,3% apresentou hematoma transoperatório que foi tratado com compressão local e antibioticoterapia. Um paciente apresentou prolapso mucoso residual (8,3%, que foi ressecado. Houve recidiva da procidência em um caso (8,3%. A melhora da incontinência ocorreu em 75% dos pacientes e uma paciente apresentou bloqueio evacuatório no primeiro mês após a cirurgia. Não houve mortalidade entre os pacientes operados. CONCLUSÃO: A retopexia transanal é uma t

  19. KAIZEN – A case study

    OpenAIRE

    Manjunath Shettar; Pavan Hiremath

    2015-01-01

    The ultimate objective of manufacturing industries is to increase productivity with high quality. At present, many manufacturing companies are facing problems such as high quality rejection, high inventories, high lead time, high costs of production, and inability to cope with customer orders. By implementing and practicing the lean production system many problems can be solved without employing high-tech and high-touch approaches but by involving people on the shop floor in Kaize...

  20. Drive Electric Vermont Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Fred [Energetics Incorporated, Columbia, MD (United States); Roberts, Dave [Vermont Energy Investment Corporation (VEIC), Burlington, VT (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States); White, Sera [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    Currently in the United States, the heavy majority of plug-in electric vehicle (PEV) sales have been in highly conducive, selected, metropolitan areas; opposed to more broad distribution across the country. The U.S. Department of Energy’s EV Everywhere Grand Challenge is looking carefully at the barriers and opportunities that exist to enable small and midsize communities to partake in the PEV market and benefit from the economic and environmental advantages of PEVs. In order to gain insight into these challenges and barriers, DOE selected a success story (i.e., Drive Electric Vermont) as the subject of this case study, as the state of Vermont is tied with Detroit, Michigan in having the highest percentage of 2014 (most recent complete data) PEV registrations for cold weather U.S. cities and has seen more than a sixfold increase in charging stations over the last three years. The overall objective of this case study was to use the lessons learned from Drive Electric Vermont to determine what activities are most effective at encouraging acquisitions of PEVs and deployment of charging infrastructure in small to midsize communities, prioritizing and sequencing their implementation, identifying robust means for extrapolation, and applying this understanding to other small to midsize communities across the nation. The Drive Electric Vermont Program was formed in 2012 with a goal of increasing the use of electrified transportation in Vermont through policy development, education and outreach, and infrastructure development. The Drive Electric Vermont Program can be broadly broken into four components: (1) strategic planning/leadership, (2) stakeholder/partnership development, (3) education and outreach, and (4) incentives. The early phases of the program focused heavily on strategic planning, and stakeholder and partnership development, followed by a transition to education and outreach activities, charging infrastructure development, and grant and incentive programs

  1. Drive Electric Vermont Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Fred [Energetics Incorporated, Columbia, MD (United States); Roberts, Dave [Vermont Energy Investment Corporation (VEIC), Burlington, VT (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States); White, Sera [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    Currently in the United States, the heavy majority of plug-in electric vehicle (PEV) sales have been in highly conducive, selected, metropolitan areas; opposed to more broad distribution across the country. The U.S. Department of Energy’s EV Everywhere Grand Challenge is looking carefully at the barriers and opportunities that exist to enable small and midsize communities to partake in the PEV market and benefit from the economic and environmental advantages of PEVs. In order to gain insight into these challenges and barriers, DOE selected a success story (i.e., Drive Electric Vermont) as the subject of this case study, as the state of Vermont is tied with Detroit, Michigan in having the highest percentage of 2014 (most recent complete data) PEV registrations for cold weather U.S. cities and has seen more than a sixfold increase in charging stations over the last three years. The overall objective of this case study was to use the lessons learned from Drive Electric Vermont to determine what activities are most effective at encouraging acquisitions of PEVs and deployment of charging infrastructure in small to midsize communities, prioritizing and sequencing their implementation, identifying robust means for extrapolation, and applying this understanding to other small to midsize communities across the nation. The Drive Electric Vermont Program was formed in 2012 with a goal of increasing the use of electrified transportation in Vermont through policy development, education and outreach, and infrastructure development. The Drive Electric Vermont Program can be broadly broken into four components: (1) strategic planning/leadership, (2) stakeholder/partnership development, (3) education and outreach, and (4) incentives. The early phases of the program focused heavily on strategic planning, and stakeholder and partnership development, followed by a transition to education and outreach activities, charging infrastructure development, and grant and incentive programs

  2. Exacerbation of hypereosinophilic syndrome with pulmonary involvement in two consecutive pregnancies: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Itai Ghersin

    2014-08-01

    Full Text Available Hypereosinophilic syndrome represents a heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and organ system dysfunction including the pulmonary system. Hypereosinophilic syndrome, with and without pulmonary involvement, in association with pregnancy is very rare, and to the best of our knowledge only one case of hypereosinophilic syndrome with pulmonary involvement during pregnancy has been previously reported in the medical literature. We describe a case of a patient with previously symptomatic hypereosinophilic syndrome with pulmonary involvement who experienced exacerbations of her disease during two consecutive pregnancies. To the best of our knowledge this is the first report which demonstrates a worsening effect of pregnancy on both eosinophil count and end organ involvement in a patient with previous diagnosis of hypereosinophilic syndrome. [Int J Res Med Sci 2014; 2(4.000: 1774-1776

  3. A STUDY OF MATHEMATICAL ABILITY INVOLVING DIGIT RELATIONSHIPS. FINAL REPORT.

    Science.gov (United States)

    KNAPP, ROBERT H.

    ATTITUDES OF STUDENTS TOWARD ARABIC NUMBERALS AND THEIR ASSOCIATIONS WITH THE NUMBERS FROM 1 TO 9 WERE INVESTIGATED IN A SERIES OF FIVE STUDIES ON (1) NONQUANTITATIVE ASSOCIATIONS TO NUMERALS AS A FUNCTION OF AGE, ABILITY LEVEL, AND SEX AMONG AMERICAN CHILDREN, (2) COLOR ASSOCIATIONS WITH NUMERALS AMONG MALE COLLEGE STUDENTS, (3) PERSONALITY…

  4. Police officers’ perceptions of interviews in cases of sexual offences and murder involving children and adult victims

    OpenAIRE

    Oxburgh, Gavin; Ost, James; Morris, Paul; Cherryman, Julie

    2015-01-01

    This paper examines 90 UK police officers’ perceptions of characteristics of interviews with suspects of rape and murder involving child and adult victims. Officers rated their beliefs about how stressful they would find such interviews, the importance of confessions, their likely emotional involvement and how much empathy they would show towards the suspect. Murder cases were reported to be more stressful than rape, and confessions were deemed to be less important for respondents compared to...

  5. Aggressive Calcifying Epithelial Odontogenic Tumor of the Maxillary Sinus with Extraosseous Oral Mucosal Involvement: A Case Report

    OpenAIRE

    Vidya Rani; Mahaboob Kadar Masthan; Babu Aravindha; Sankari Leena

    2016-01-01

    Calcifying epithelial odontogenic tumors are benign odontogenic neoplasms whose occurrence in the maxillary sinus is rare. Maxillary tumors tend to be locally aggressive and may rapidly involve the surrounding vital structures. We report a case of a large calcifying epithelial odontogenic tumor of the maxilla, involving the maxillary sinus in a 48-year-old woman. The tumor was largely intraosseous. In the canine and first premolar regions, the loss of bone could be palpated but the oral mucos...

  6. Roadmaster Roading Contractors Case Study

    Directory of Open Access Journals (Sweden)

    Hazel Taylor

    1999-01-01

    Full Text Available Systems analysis students seldom experience the practical difficulties of the initial investigation into a client’s requirements. They get little chance to practice the skills they need to investigate complex and confused problem situations, or to appreciate the wider organizational issues that can impact on a situation. This teaching case is designed to give students the opportunity to practice and apply investigation skills and to challenge them to consider the wider work environment when considering possible solutions to a problem situation. The case is conducted as a role-play, with students acting as systems analysts and teaching staff role-playing the clients. The students develop a report analyzing the client’s situation based on the issues that arise during the interviews. Feed-back sessions focus on discussing how well the students applied various interviewing strategies previously covered in lectures, and on the wider organizational problems that could impact proposed information system solutions.

  7. Study on Case Teaching of Financial Management

    Science.gov (United States)

    Che, Zhenghong; Che, Zhengmei

    2011-01-01

    Case teaching is an efficient teaching method of management. It plays an important role to enhance the students' ability to practice the theory. However, case teaching of financial management has not achieved the expected results. The paper aims to study the importance, characteristics and corresponding methods of case teaching method of financial…

  8. Metastatic lesions involving the sella: Report of three cases and review of the literature

    Directory of Open Access Journals (Sweden)

    Weilbaecher Christina

    2004-07-01

    Full Text Available Metastatic cancer must be considered as a possibility for intrasellar masses. Newer treatment modalities, such as gamma knife radiosurgery needs to be explored for these lesions. Three cases of intrasellar metastatic lesions were retrospectively reviewed. Presenting complaints, radiographic studies, operative procedure, and histopathological confirmation were recorded for each patient. All had an unknown primary malignancy prior to the presentation with the intrasellar lesion detected by magnetic resonance imaging (MRI. Presenting symptoms were diplopia with extraocular movement deficits in all patients. Transsphenoidal resection or biopsy was performed. Histopathological analysis revealed small cell carcinoma in two patients and plasmacytoma in one. All patients received postoperative radiation and/or chemotherapy. Survival following initial presentation was 2 months and 6 months for two of the patients; the third patient is alive at 2-month follow-up.

  9. Complex Variant of Philadelphia Translocation Involving Chromosomes 9, 12, and 22 in a Case with Chronic Myeloid Leukaemia

    Directory of Open Access Journals (Sweden)

    F. Malvestiti

    2014-01-01

    Full Text Available Chronic myeloid leukemia (CML is a hematopoietic stem cell disorder included in the broader diagnostic category of myeloproliferative neoplasms, associated with fusion by BCR gene at chromosome 22q11 to ABL1 gene at chromosome 9q34 with the formation of the Philadelphia (Ph chromosome. In 2–10% of CML cases, the fusion gene arises in connection with a variant translocation, involving chromosomes 9, 22, and one or more different chromosomes; consequently, the Ph chromosome could be masked within a complex chromosome rearrangement. In cases with variant Ph translocation a deletion on der(9 may be more frequently observed than in cases with the classical one. Herein we describe a novel case of CML with complex variant Ph translocation involving chromosomes 9, 12, and 22. We present the hematologic response and cytogenetic response after Imatinib treatment. We also speculated the mechanism which had originated the chromosome rearrangement.

  10. Study of the mechanisms involved in reactive silica

    Energy Technology Data Exchange (ETDEWEB)

    Boinski, Frederic [Univ Lille Nord of France, Ecole des Mines, 941, rue Charles Bourseul, BP 838, 59508 Douai (France); Khouchaf, Lahcen, E-mail: lahcenkho@live.fr [Univ Lille Nord of France, Ecole des Mines, 941, rue Charles Bourseul, BP 838, 59508 Douai (France); Tuilier, Marie-Helene [Universite de Haute-Alsace, LPMT (EA CNRS 4365), Universite de Haute Alsace, 61 rue Albert Camus, F-68093 Mulhouse (France)

    2010-07-01

    The microstructure of a heterogeneous SiO{sub 2} submitted to a depolymerisation process is studied using Transmission Electron Microscope (TEM), Environmental SEM (ESEM), and X-ray diffraction (XRD). With ESEM the formation of micro domain induced by the dissolution phenomena is shown. XRD shows the formation of a halo that is associated with the formation of amorphous phase. The parameters 'position and FWHM' of the halo, enabled us to show the evolution of the disorderly phase when the reaction progresses. The hypothesis of formation of nanoparticles with different structural states was confirmed by the TEM.

  11. Managing Communication during a School Crisis: A Case Study

    Science.gov (United States)

    Gentilucci, James L.

    2007-01-01

    Crisis communication training of school principals is problematic because it overemphasizes media relations and underemphasizes the critical importance of immediate and personal communication with students, staff, and parents--those most affected by school crises. A case study involving the death of a student in a small rural school explains why…

  12. A New Lean Paradigm in Higher Education: A Case Study

    Science.gov (United States)

    Doman, Mark S.

    2011-01-01

    Purpose: This case study aims to demonstrate that lean principles and practices utilized in industry can be successfully applied to improve higher education administrative processes through an innovative and engaging learning experience involving undergraduate students. Design/methodology/approach: This is a first-hand account by the instructor of…

  13. The use of full spectrum digital photography for evidence collection and preservation in cases involving forensic odontology.

    Science.gov (United States)

    Wright, Franklin D; Golden, Gregory S

    2010-09-10

    Photography often represents the best method to collect and preserve evidence in forensic cases. This is especially true in forensic odontology with cases involving dental identification, human abuse and, perhaps most significantly, bitemark cases. Basic visible light photography is adequate in most dental identification cases; however, full spectrum digital photography is best utilized to collect all available evidence in cases of human abuse and bitemarks. This paper will discuss the types of photographic evidence that should be collected with various forensic odontological cases and the specific techniques utilized in full spectrum forensic digital photography. The use of full spectrum photography captures the forensic injuries using special techniques recording the injuries in each of the four resultant events that occur when light strikes skin.

  14. The Case Study as Research Heuristic: Lessons from the R&D Value Mapping Project.

    Science.gov (United States)

    Bozeman, Barry; Klein, Hans K.

    1999-01-01

    Examines the role of prototype case studies as the foundation for later evaluation through two studies from the "R&D Value Mapping Project," a study that will involve more than 30 cases. Explores the usefulness of case studies in defining and assessing subsequent research efforts. (SLD)

  15. Academic Planning: Four Institutional Case Studies.

    Science.gov (United States)

    Kieft, Raymond N.

    As part of a project studying intrainstitutional planning, management, and evaluation, four case studies were undertaken in 1976 of academic planning at Villa Maria College, Kansas City Metropolitan Community College District, West Virginia University, and Western Washington University. The case studies were part of an ongoing project, the…

  16. A Case Report: The Diagnosis and Therapeutic Evaluation for a Rare Disease of Langerhans Cell Histiocytosis Involving Thyroid

    Science.gov (United States)

    Cai, Ye-Feng; Wang, Qing-Xuan; Ni, Chun-Jue; Dong, Si-Yang; Lv, Lin; Li, Quan; Chen, En-Dong; Zhang, Xiao-Hua

    2015-01-01

    Abstract Langerhans cell histiocytosis (LCH) involving the thyroid gland is extremely rare. Currently, the diagnosis and therapeutic evaluation for LCH involving thyroid is a challenge. We reported a rare case of LCH involving thyroid, presenting as painless thyroid goiters, and successfully performed positron emission tomography/computed tomography (PET/CT) to make an accurate diagnosis and therapeutic evaluation for LCH. Although the histology or cytology is the golden standard for the diagnosis of LCH involving thyroid, the PET/CT should be keep in mind when LCH involving thyroid with inconclusive cytologic results. During the treatment of LCH, PET/CT can be performed to assess the therapeutic effect and select the most effective and reliable treatment for LCH. PMID:26554785

  17. Isotretinoin-induced acute severe myopathy involving pelvic girdle muscles: A case report

    Science.gov (United States)

    Sameem, Farah; Semira

    2016-01-01

    Oral isotretinoin has been in widespread use for more than three decades. It causes numerous side effects; skin and mucous membrane being commonly involved. Musculoskeletal adverse effects are also known to occur, but pelvic girdle myopathy is rarely reported. We report myopathy involving pelvic girdle muscles in a young male who received oral isotretinoin for folliculitis decalvans.

  18. Liverpool Telecare Pilot: case studies

    Directory of Open Access Journals (Sweden)

    Nigel Barnes

    2006-09-01

    Full Text Available Telecare services use information and communications technology (ICT to support the provision of care to people in their own homes. This paper describes a pilot telecare service employed by Liverpool (UK City Council to support a sample of their frail and elderly social services users. The pilot has been running for over two years and has been deployed for 21 individuals in Liverpool. In this paper we present the pilot system and provide real example cases which help to illustrate the benefits of such a system.

  19. PUREX transition project case study

    Energy Technology Data Exchange (ETDEWEB)

    Jasen, W.G.

    1996-04-15

    In December 1992, the US Department of Energy (DOE) directed that the Plutonium-Uranium Extraction (PUREX) Plant be shut down and deactivated because it was no longer needed to support the nation`s production of weapons-grade plutonium. The PUREX/UO{sub 2} Deactivation Project will establish a safe and environmentally secure configuration for the facility and preserve that configuration for 10 years. The 10-year span is used to predict future maintenance requirements and represents the estimated time needed to define, authorize, and initiate the follow-on decontamination and decommissioning activities. Accomplishing the deactivation project involves many activities. Removing major hazards, such as excess chemicals, spent fuel, and residual plutonium are major goals of the project. The scope of the PUREX Transition Project is described within.

  20. A Pilot Study Involving the Effect of Two Different Complex Training Protocols on Lower Body Power

    Directory of Open Access Journals (Sweden)

    Smith Chad E.

    2014-09-01

    Full Text Available Purpose. Complex training (CT involves the coupling of two exercises ostensibly to enhance the effect of the second exercise. Typically, the first exercise is a strength exercise and the second exercise is a power exercise involving similar muscles. In most cases, CT is designed to enhance power. The purpose of this study was twofold. First, this study was designed to determine if lower body power could be enhanced using complex training protocols. Second, this study investigated whether the inclusion of a power exercise instead of a strength exercise as the first exercise in CT would produce differences in lower body power. Methods. Thirty-six recreationally-trained men and women aged 20 to 29 years attending a college physical education course were randomly assigned to one of three groups: squat and countermovement squat jumps (SSJ, kettlebell swings and countermovement squat jumps (KSJ, and a control (CON. Training involving CT lasted 6 weeks. All participants were pre- and posttested for vertical jump performance in order to assess lower body power. Results. Vertical jump scores improved for all groups (p < 0.01. The results also indicated that there were no statistically significant differences between group scores across time (p = 0.215. The statistical power for this analysis was low (0.312, most likely due to the small sample size. However, the results did reveal a trend suggesting that the training improvements were greater for both the SSJ and KSJ groups compared with the CON (by 171% and 107%, respectively although significance was not reached. Conclusions. Due to the observed trend, a replication of this study with a greater number of participants over a longer period of time is warranted.

  1. LOFAR-UK White Paper: A Science case for UK involvement in LOFAR

    CERN Document Server

    Best, P N

    2008-01-01

    LOFAR, the Low-Frequency Array, is a next-generation software-driven radio telescope operating between 30 and 240MHz, currently under construction by ASTRON in the Netherlands. This low frequency radio band is one of the few largely unexplored regions of the electromagnetic spectrum. The sensitivity and angular resolution offered by LOFAR will be two to three orders of magnitude better than existing telescopes, and as such it will open up this new window on the Universe. LOFAR will impact on a broad range of astrophysics, from cosmology to solar system studies. There is growing European involvement in LOFAR, driven by the need to add stations far from the main core in order to improve angular resolution. LOFAR-UK is a project aimed at cementing UK participation in LOFAR via the operation of four stations within the UK. LOFAR-UK ground stations will allow LOFAR observations to reach sub-arcsecond scales at the highest frequencies, and as a result will also improve the (confusion-limited) sensitivity limit of t...

  2. Tactile Astronomy - a Portuguese case study

    Science.gov (United States)

    Canas, L.; Alves, F.; Correia, A.

    2012-09-01

    Although astronomy plays an important role in the most various outreach initiatives, as well as school science curricula, due to its strong visual component in knowledge acquisition, astronomy subjects are not entirely well addressed and accessed by visually impaired students and/or general public. This stresses the need of more tactile material production, still very scarce in an educational context whether formal or informal. This is a case study activity developed based on different schematic tactile images of several objects present in our solar system. These images in relief, highlight, through touch, several relevant features present in the different astronomical objects studied. The scientific knowledge is apprehended through the use of a tactile key, complemented with additional information. Through proper hands-on activities implementation and careful analysis of the outcome, the adapted images associated with an explanatory key prove to be a valuable resource in tactile astronomy domain. Here we describe the process of implementing such initiative near visually impaired students. The struggles and challenges perceived by all involved and the enrichment experience of engaging astronomy with visually impaired audiences, broadening horizons in an overall experience accessible to all.

  3. The Diffuse Involvement of Bilateral Breasts in the Incidence of Burkitt's Lymphoma: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Myung Su; Lee, Sa Rah; Yang, Woo Ick; Kim, Eun Kyung [Yonsei University College of Medicine, Seoul (Korea, Republic of); Jung, Hae Kyoung [CHA University, Bundang CHA Hospital, Seongnam (Korea, Republic of)

    2009-12-15

    The incidence of Burkitt's lymphoma involving both breasts is rare. We report such a case that was diagnosed by a core biopsy of a hypoechoic lesion visualized from the ultrasonographic results of a patient that was clinically suspected of mastitis.

  4. 78 FR 17744 - Social Security Ruling, SSR 13-2p; Titles II and XVI: Evaluating Cases Involving Drug Addiction...

    Science.gov (United States)

    2013-03-22

    ... ADMINISTRATION Social Security Ruling, SSR 13-2p; Titles II and XVI: Evaluating Cases Involving Drug Addiction and Alcoholism (DAA); Correction AGENCY: Social Security Administration. ACTION: Notice of Social Security Ruling; Correction. SUMMARY: The Social Security Administration published a document in...

  5. The Relationship between Faculty Involvement in Governance and Faculty Vitality: The Case of North Carolina Community Colleges

    Science.gov (United States)

    Madray, Van

    2009-01-01

    This study examines the effects of governance involvement on the vitality of community college faculty members. This study explores the degree to which involvement in the governance of a college through a faculty senate fosters the vitality of elected faculty members. While faculty vitality is a difficult concept to measure directly, faculty…

  6. Structuring an integrated care system: interpreted through the enacted diversity of the actors involved – the case of a French healthcare network

    Directory of Open Access Journals (Sweden)

    Corinne Grenier

    2011-02-01

    Full Text Available Research question: We are looking at the process of structuring an integrated care system as an innovative process that swings back and forth between the diversity of the actors involved, local aspirations and national and regional regulations. We believe that innovation is enriched by the variety of the actors involved, but may also be blocked or disrupted by that diversity. Our research aims to add to other research, which, when questioning these integrated systems, analyses how the actors involved deal with diversity without really questioning it. Case study: The empirical basis of the paper is provided by case study analysis. The studied integrated care system is a French healthcare network that brings together healthcare professionals and various organisations in order to improve the way in which interventions are coordinated and formalised, in order to promote better detection and diagnosis procedures and the implementation of a care protocol. We consider this case as instrumental in developing theoretical proposals for structuring an integrated care system in light of the diversity of the actors involved. Results and discussion: We are proposing a model for structuring an integrated care system in light of the enacted diversity of the actors involved. This model is based on three factors: the diversity enacted by the leaders, three stances for considering the contribution made by diversity in the structuring process and the specific leading role played by those in charge of the structuring process.  Through this process, they determined how the actors involved in the project were differentiated, and on what basis those actors were involved. By mobilizing enacted diversity, the leaders are seeking to channel the emergence of a network in light of their own representation of that network. This model adds to published research on the structuring of integrated care systems.

  7. Structuring an integrated care system: interpreted through the enacted diversity of the actors involved – the case of a French healthcare network

    Directory of Open Access Journals (Sweden)

    Corinne Grenier

    2011-02-01

    Full Text Available Research question: We are looking at the process of structuring an integrated care system as an innovative process that swings back and forth between the diversity of the actors involved, local aspirations and national and regional regulations. We believe that innovation is enriched by the variety of the actors involved, but may also be blocked or disrupted by that diversity. Our research aims to add to other research, which, when questioning these integrated systems, analyses how the actors involved deal with diversity without really questioning it.Case study: The empirical basis of the paper is provided by case study analysis. The studied integrated care system is a French healthcare network that brings together healthcare professionals and various organisations in order to improve the way in which interventions are coordinated and formalised, in order to promote better detection and diagnosis procedures and the implementation of a care protocol. We consider this case as instrumental in developing theoretical proposals for structuring an integrated care system in light of the diversity of the actors involved.Results and discussion: We are proposing a model for structuring an integrated care system in light of the enacted diversity of the actors involved. This model is based on three factors: the diversity enacted by the leaders, three stances for considering the contribution made by diversity in the structuring process and the specific leading role played by those in charge of the structuring process.  Through this process, they determined how the actors involved in the project were differentiated, and on what basis those actors were involved. By mobilizing enacted diversity, the leaders are seeking to channel the emergence of a network in light of their own representation of that network. This model adds to published research on the structuring of integrated care systems.

  8. Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population.

    Directory of Open Access Journals (Sweden)

    Huiying He

    Full Text Available BACKGROUND: Dental agenesis is the most common, often heritable, developmental anomaly in humans. Although WNT10A gene mutations are known to cause rare syndromes associated with tooth agenesis, including onycho-odontodermal dysplasia (OODD, Schöpf-Schulz-Passarge syndrome (SSPS, hypohidrotic ectodermal dysplasia (HED, and more than half of the cases of isolated oligodontia recently, the genotype-phenotype correlations and the mode of inheritance of WNT10A mutations remain unclear. The phenotypic expression with WNT10A mutations shows a high degree of variability, suggesting that other genes might function with WNT10A in regulating ectodermal organ development. Moreover, the involvement of mutations in other genes, such as EDA, which is also associated with HED and isolated tooth agenesis, is not clear. Therefore, we hypothesized that EDA mutations interact with WNT10A mutations to play a role in tooth agenesis. Additionally, EDA, EDAR, and EDARADD encode signaling molecules in the Eda/Edar/NF-κB signaling pathways, we also checked EDAR and EDARADD in this study. METHODS: WNT10A, EDA, EDAR and EDARADD were sequenced in 88 patients with isolated oligodontia and 26 patients with syndromic tooth agenesis. The structure of two mutated WNT10A and two mutated EDA proteins was analyzed. RESULTS: Digenic mutations of both WNT10A and EDA were identified in 2 of 88 (2.27% isolated oligodontia cases and 4 of 26 (15.38% syndromic tooth agenesis cases. No mutation in EDAR or EDARADD gene was found. CONCLUSIONS: WNT10A and EDA digenic mutations could result in oligodontia and syndromic tooth agenesis in the Chinese population. Moreover, our results will greatly expand the genotypic spectrum of tooth agenesis.

  9. Rearrangements involving 12p12 in two cases of cardiac myxoma

    NARCIS (Netherlands)

    Dijkhuizen, T; Berg, E van den; Molenaar, W M; Meuzelaar, J J; de Jong, Bauke

    1995-01-01

    Recently, we reported on the cytogenetic analysis of a case of cardiac myxoma, revealing a 46,XY,der(7)t(7;17)(p21;p11), add (10) (q22), add (12) (p12), del(17)(p11) chromosomal pattern. In this article we present the cytogenetic analysis of another case of cardiac myxoma, in which we found several

  10. Comparative Study of the Critical Chain and PERT Planning Methods: No Bad Human Behaviors Involved

    Directory of Open Access Journals (Sweden)

    Chia-Ling Huang

    2012-08-01

    Full Text Available Since 1997, Critical Chain Project Management (CCPM method has received a lot of attention and hundreds of successful cases have also been reported and all claims that it is possible to rapidly achieve highly reliable on-time delivery (OTD with short project lead time (PLT in multi-project environment. The main reason that CCPM can achieve highly reliable OTD and short PLT in multi-project environment can be contributed to that CCPM makes good use of safety time imbedded in tasks by two changes: logistical change and bad human behaviors change. However, if no bad human behaviors involved, does the mere emphasis on logistical change contributed to the success of project time reduction and OTD improvement? This is the key question still remained. A comparative study of the critical chain and Program Evaluation and Review Technique (PERT planning methods, no bad human behaviors involved, was performed in this study. The simulation results showed that in terms of mean project time, CCPM is no significantly better than PERT. However, in terms of plan reliability, CCPM achieve higher reliable than PERT did and this is the contribution of CCPM logistical change.

  11. Summary of case studies for cooperation mechanisms

    DEFF Research Database (Denmark)

    Longa, Francesco Dalla; Klinge Jacobsen, Henrik; Hansen, Lise-Lotte Pade;

    2012-01-01

    This document is a summary report highlighting the main aspect analyzed in the RES4LESS case studies. The document starts with an introductory chapter where the background that led to the selection of the case studies is outlined. In the following three chapters the case studies are presented......, highlighting the most relevant results. A brief chapter concludes the document, giving an outlook on the follow-up activities of the RES4LESS project. This summary is intended not only as an introduction to the RES4LESS cases studies, but also as a guideline to read and interpret the in-depth analysis carried...... out in the final documents that describe the case studies in detail. These documents will be published in September 2012 on the RES4LESS website, www.res4less.eu....

  12. Regional case studies--Africa.

    Science.gov (United States)

    Prentice, Andrew M

    2009-01-01

    Africa is the final continent to be affected by the nutrition transition and, as elsewhere, is characterized by the paradoxical coexistence of malnutrition and obesity. Several features of the obesity epidemic in Africa mirror those in other emerging nations: it penetrates the richer nations and urban areas first with a strong urban- rural gradient; initially it affects the wealthy, but later there is a demographic switch as obesity becomes a condition more associated with poverty, and it shares many of the same drivers related to the increasing affordability of highly refined oils and carbohydrates, and a move away from subsistence farm work and towards sedentary lifestyles. Africa also has some characteristics of the obesity epidemic that stand out from other regions such as: (1) excepting some areas of the Pacific, Africa is probably the only region in which obesity (especially among women) is viewed culturally as a positive and desirable trait, leading to major gender differences in obesity rates in many countries; (2) most of Africa has very low rates of obesity in children, and to date African obesity is mostly an adult syndrome; (3) Africans seem genetically prone to higher rates of diabetes and hypertension in association with obesity than Caucasians, but seem to be relatively protected from dislipidemias; (4) the case-specific deaths and disabilities from diabetes and hypertension in Africa are very high due to the paucity of health services and the strain that the 'double burden' of disease places on health systems.

  13. Leishmaniasis in dogs: Case study

    Directory of Open Access Journals (Sweden)

    Aleksić Jelena

    2009-01-01

    Full Text Available The paper presents a case of leishmaniasis in a 2.5-month-old dog imported from France. The clinical examination established a generally poor state of health, expressed cachexia, atrophy of the temporal musculature, weakness of movement, as well as abnormally long and brittle nails. There was also hyperkeratosis of the nose tip and paws. A histological examination of biopsy sections of the altered skin parts showed inflammatory changes in the area of the dermis, together with infiltration of macrophages and a smaller number of lymphocytes, plasmocytes and neutrophil granulocytes in the area around the sebaceous glands and hair follicles. The determined changes correspond to superficial dermatitis. Edema followed by partial degeneration of connective-tissue fibers is observed in connective tissue. A smaller number of intracellular parasitic forms was established in mononuclear cells. A smaller number of oval amastigotes with round dark red nucleis were observed in sections stained using the Gimza method in the cytoplasm of macrophages located in the dermis, but also extracellularly. It was concluded that the dog was diseased with leishmaniasis on the grounds of the clinical picture and the microscopic findings.

  14. The Evaluation of Amyloidosis Cases with Renal Involvement: A Single-Center Experience

    Directory of Open Access Journals (Sweden)

    Yavuz AYAR

    2015-09-01

    Full Text Available OBJECTIVE: Amyloidosis is a chronic disease associated with proteinuria and can progress to renal failure. The diagnosis and treatment of the underlying cause is therefore important. In this study at a university hospital, the diagnosis of amyloidosis patients with renal biopsies was evaluated retrospectively. MATERIAL and METHODS: 69 (42 males, 27 females, mean age: 51.7 ± 14.8 years patients were diagnosed with amyloidosis with renal biopsy. Indications for biopsy was nephrotic syndrome in 42 patients (60.9%, nephritic syndrome in 27 (39.1% and renal dysfunction with proteinuria in 31 (44.9%. RESULTS: The most common causes of secondary amyloidosis were Familial Mediterranean Fever in 17 of the 62 patients, chronic inflammatory diseases in 17 patients and chronic infection in 13 patients. No cause was determined in 12 patients. Multiple myeloma was present in 5 patients with primary amyloidosis. At the time of diagnosis with amyloidosis, 19 patients were stage 1, 15 stage 2, 5 stage 3A, 12 stage 3B, 10 stage 4 and 8 stage 5. The baseline hemoglobin, serum albumin, creatinine, sodium, potassium, calcium, phosphorus, AST, ALT, PTH, SAA, CRP levels, average daily urinary protein excretion and baseline GFR values were not significantly different in primary and secondary amyloidosis patients. The treatment was medical in 62.3% of the patients, dialysis in 31.9% and renal transplantation in 5.8%. CONCLUSION: The reliability of renal biopsy in the diagnosis of amyloidosis is high. However, genetic studies for the diagnosis of idiopathic cases and special histological staining methods should be considered.

  15. Involvement of larder beetles (Coleoptera: Dermestidae) on human cadavers: a review of 81 forensic cases.

    Science.gov (United States)

    Charabidze, Damien; Colard, Thomas; Vincent, Benoit; Pasquerault, Thierry; Hedouin, Valery

    2014-11-01

    From 1994 to 2013, French forensic entomology laboratories investigated 1,093 cases. Larder beetles (Coleoptera: Dermestidae) were observed in 81 (7.5%) of these cases. To describe and analyze these 81 cases, eight parameters were used: city, location (indoor or outdoor), decay stage (fresh, decay, or dry), dermestid species and instar (adults and/or larvae), presence of living calliphorid larvae, presence of calliphorid pupae or adults, and presence of other necrophagous species. Eight Dermestidae species were observed: Dermestes frischii (42% of cases), Dermestes undulatus (35.8%), Dermestes peruvianus (12.3%), Dermestes lardarius (9.9%), Dermestes haemorrhoidalis (8.6%), Dermestes maculatus (7.4%), Dermestes bicolor (3.7%), and Dermestes ater (1.2%). Larder beetles primarily developed on human cadavers in outdoor locations in areas with a dry climate and were never reported in oceanic areas (which are characterized by frequent rainfall and high ambient humidity). The number of dermestid species on a single corpse never exceeded three. Typically, one species was found per corpse. Species differed between indoor and outdoor cases, with D. frischii and D. undulatus dominant in outdoor cases, while D. peruvianus dominant in indoor cases. Calliphoridae was found in 88% of the cases, while Hydrotaea and Piophilidae were observed 40% of the time. Regarding Coleoptera, Necrobia spp. (Coleoptera: Cleridae) was observed in 46% of the cases. Lastly, we observed a typical decomposition pattern, with preferential feeding areas on the face, hands, and feet (i.e., the extremities). Pupation chambers on or inside the bones were not observed.

  16. Rebranding: a Case Study Approach

    OpenAIRE

    Size, Maria, (Thesis)

    2005-01-01

    The primary objective of this study is to explore how and why companies implement rebranding campaigns. The study stemmed from a realisation by the author that the area of rebranding is very much under-researched academically although anecdotal evidence indicates and increase in the occurrence of the phenomenon in recent years. Therefore the purpose of this research is to add to the insufficient body of literature on rebranding through exploring it from a corporate perspective. The two chapte...

  17. Hybrid Risk Management Methodology: A Case Study

    Directory of Open Access Journals (Sweden)

    Jacky Siu-Lun Ting

    2009-10-01

    Full Text Available Risk management is a decision-making process involving considerations of political, social, economic and engineering factors with relevant risk assessments relating to a potential hazard. In the last decade, a number of risk management tools are introduced and employed to manage and minimize the uncertainty and threats realization to the organizations. However, the focus of these methodologies are different; in which companies need to adopt various risk management principles to visualize a full picture of the organizational risk level. Regarding to this, this paper presents a new approach of risk management that integrates Hierarchical Holographic Modeling (HHM, Enterprise Risk Management (ERM and Business Recovery Planning (BCP for identifying and assessing risks as well as managing the consequences of realized residual risks. To illustrate the procedures of the proposed methodology, a logistic company ABC Limited is chosen to serve as a case study Through applying HHM and ERM to investigate and assess the risk, ABC Limited can be better evaluated the potential risks and then took the responsive actions (e.g. BCP to handle the risks and crisis in near future.

  18. [Clostridium difficile and cytomegalovirus involved in a case of pseudomembranous colitis].

    Science.gov (United States)

    García, Coralith; Velarde, Juan; Cedron, Hugo; Ferrufino, Juan Carlos; Seas, Carlos; Bussalleu, Alejandro; Gotuzzo, E; Gotuzzo, Eduardo

    2007-01-01

    We report an unusual case of pseudomembranous colitis with fatal outcome where C. difficile and cytomegalovirus coexistense in a Peruvian patient with AIDS and gastrointestinal compromise by a mycobacterium.

  19. Case Study Methodology and Homelessness Research

    Directory of Open Access Journals (Sweden)

    Jill Pable

    2013-10-01

    Full Text Available This paper describes the potential suitability of case study methodology for inquiry with the homeless population. It references a research study that uses case study research method to build theory. This study's topic is the lived experience of destitute individuals who reside in homeless shelters, and explores the homeless shelter built environment's potential influence on resident satisfaction and recovery. Case study methodology may be appropriate because it explores real-life contextual issues that characterize homelessness and can also accommodate the wide range of homeless person demographics that make this group difficult to study in a generalized fashion. Further, case study method accommodates the need within research in this area to understand individualized treatments as a potential solution for homelessness.

  20. A case of Erdheim Chester disease with central nervous system involvement

    Directory of Open Access Journals (Sweden)

    Anil Kumar Patil

    2015-01-01

    Full Text Available Erdheim Chester disease (ECD is a rare non-Langerhans cell histiocytosis, commonly involving the musculoskeletal system. Other tissue can also be involved, including the central nervous system with wide spectrum of clinical features, at times being nonspecific. This can cause diagnostic dilemmas with delay in diagnosis and initiation of therapy. Here we describe a 63-year-old man who had presented with ataxia and behavioral changes, bony pains, weight loss, and fatigue. His computed tomography (CT, 99Tc scintigraphy and histopathological features on bone biopsy were consistent with ECD. Thus, ECD should be considered as a differential diagnosis in patients presenting with bony pain and nonspecific features of multiorgan involvement.

  1. Case Study on Quality Education

    Science.gov (United States)

    Habib, Zahida

    2011-01-01

    Quality of Education, especially at Primary level, is an important issue to be discussed at the International Forum. This study highlights the quality of primary education through a comparison of the quality of Community Model Schools and Govt. Girls Primary Schools in Pakistan. Community Model Schools were established under Girls Primary…

  2. A Case Study of Engineering Ethics

    Science.gov (United States)

    Shimizu, Kazuo

    In Engineering Ethics Class at Shizuoka University, the Code of Ethics and Cases for Electrical Engineers by IEEJ Ethics committee is used to promote for high education effect to correspond large number of students (140students). In this paper, a case study in the class, and survey results for ethics value of students are presented. In addition, some comments for role playing act on the case of virtual experiences by students are described.

  3. Evaluation of mandibular bone involvement by oral malignant tumors using scintigraphy of Tc-99m MDP and Ga-67 citrate. Intensely invaded cases

    Energy Technology Data Exchange (ETDEWEB)

    Katada, Yoshiaki; Tsuchimochi, Makoto; Kato, Joji

    1987-12-01

    Ten patients with intensely invaded malignant tumors at the mandibles were studied with bone scintigraphy (Tc-99m MDP) and Ga-67 citrate scintigraphy. All patients were classified by type of accumulation of both radionuclide pharmaceuticals. In almost all patients with invaded malignant tumors, bone scintigraphy revealed decreasing uptake in the center of the lesion and increasing uptake in the peripheral region. Ga-67 citrate scintigram showed increasing concentrated accumulation which was smaller than the area of Tc-99m MDP uptake in almost all cases. These types of accumulation were compared with those of other oral and maxillo-facial diseases. The patterns of accumulation of both radionuclide pharmaceuticals in ameloblastoma (3 cases), radicular cyst (3 cases), bone fracture (2 cases), diffuse sclerosing osteomyelitis (2 cases), and one sagittal ramus osteotomy case were different from that of bone involvement of malignant tumor cases. From the types of accumulation, we may be able to differentiate the oral and maxillo-facial diseases to some extent. In addition, the intensity of accumulation of Tc-99m MDP was measured by using bone to soft tissue ratio (4 hrB/St ratio). The mean 4 hrB/St ratio was higher in moth-eaten absorbed type than in permeated type of resorption in roentgenogram. However, we could not obtain a definitive conclusion because of too few cases. The mean 4 hrB/St ratio in the bone involvement by malignant tumor was higher than that in radicular cyst, and lower than that of diffuse sclerosing osteomyelitis. Unfortunately, we could not differentiate each disease of the involved malignant tumor, ameloblastoma, or bone fracture by only the 4 hrB/St ratio. The Tc-99m MDP accumulated beyond the region where the radiolucencies exist in roentgenograms. We consider that both scintigraphies have a great role in planning surgical treatment, especially in selecting osteotomy.

  4. Marketing-Indonesia case study

    OpenAIRE

    Kurniawan, Iwan; Roshetko, James M.

    2007-01-01

    The purpose of research are (1) to identify the potential VAF species or products for Nanggung Farmers; (2) identify market channels & marketing problems; (3) enhances farmers' understanding of market mechanism; and (4) identify opportunities to improve the quantity & quality of VAF. The study was conducted on Sept-Oct 2006. Data and information are collected through Focus Group Discussion (FGD) in each village that attended both men and women. LTRA-5 (Agroforestry and Sustainable Vegetabl...

  5. Environmental contracting: a case study

    OpenAIRE

    Kubiak, Joseph C.

    1994-01-01

    Approved for public release, distribution unlimited The end of cold war levels of defense expenditures has promoted the reduction in the number of defense-related companies, creating potential monopolistic economic scenarios for defense procurement. This thesis studies one methodology to deal with these scenarios, based on the Baron-Myerson monopolist regulation mechanisms. The Baron-Myerson mechanism provides a tool to regulate monopolists when their costs are unknown or cannot be measure...

  6. ERPs KEY SUCCESS FACTORS: A CASE STUDY INVOLVING A PROBLEMATIC IMPLANTATION IN A MID-SIZE MANUFACTURING ENTERPRISE FATORES-CHAVE NA IMPLANTAÇÃO DE ERPS: ESTUDO DE UM CASO PROBLEMÁTICO EM UMA MÉDIA INDÚSTRIA

    Directory of Open Access Journals (Sweden)

    George Leal Jamil

    2009-12-01

    Full Text Available Although Information Systems' literature contains more ERP success cases, it is not rare to notice unsuccessful ERP deployments that extend over years and consume much more financial and human resources than expected. One of the reasons for that is related to the fact that ERP implementation is a social-technical multifaceted and complex process. The key success factors for ERP deployment comprises varied features such as strategic planning, project management, consulting team performance, user involvement, and top management support. This paper intends to investigate an ERP deployment case that is considered unsuccessful due to the low level of user satisfaction. The ERP's key success factors presented in literature were compared to the characteristics of this actual ERP implementation. The case study was performed in a medium-size aluminium and copper recycling industry located in the Belo Horizonte metropolitan area, the capital of Minas Gerais state, in Brazil. The research results provided evidence that the unsuccessful ERP project was partially generated by the insufficient presence of critical success factors suggested in the ERP literature. Embora a literatura contenha mais casos de sucesso de ERP, não é raro constatar implantações mal sucedidas que se estendem por vários anos e consomem muito mais recursos humanos e financeiros do que o esperado. Um dos motivos pelos quais isso ocorre é o fato de que a implantação de um ERP é um processo sócio-técnico complexo e multifacetado. Os fatores-chave de sucesso na implantação de sistemas ERP contemplam variados aspectos tais como planejamento estratégico, gerência do projeto, atuação da equipe de consultoria externa, envolvimento de usuários, apoio da alta administração, entre outros. O presente trabalho se propõe a investigar uma implantação de ERP percebida como razoavelmente mal sucedida em função do baixo grau de satisfação dos seus usuários. Os fatores-chave de

  7. Linguistic Overgeneralization: A Case Study

    Directory of Open Access Journals (Sweden)

    Wasan Nazar Al-Baldawi

    2011-08-01

    Full Text Available The current study described a single child’s language acquisition. The importance of this study resided in the circumstances and the environment in which the child lived. He came from a family in which the parents were from different countries and cultures; spoke different Arabic dialects and who lived in a country in which English is spoken. The child was in his critical period of language acquisition. He seemed to have established a unique way of communicating with people surrounding him to cope with all the linguistic varieties around him. The study showed that the child had semantic, syntactic and morphological overgeneralized structures. The data and results showed that overgeneralization and language acquisition were primarily an innate faculty of the human mind and that imitation did played a primary role in language acquisition.It showed, nevertheless, that imitation and behaviorist approaches could not fully account for language acquisition nor did the generative approach. The results went in favor of an Emergentist approach of language acquisition where both innateness and imitations were crucial constituents of children’s acquisition of linguistic forms.

  8. An adult case of chronic myelogenous leukemia with myeloblastic involvement of the central nervous system.

    Directory of Open Access Journals (Sweden)

    Watanabe,Akiharu

    1984-06-01

    Full Text Available A 31-year-old female with chronic myelogenous leukemia, who developed myeloblastic involvement of the central nervous system during acute myeloblastic transformation of the disease, was treated with methotrexate intrathecally. The therapy produced prompt clinical response and complete reversal of abnormal cerebrospinal fluid findings. However, the patient expired 10 months following the acute blastic crisis.

  9. A Case of Swyer-James (Macleod’s) Syndrome with Bilateral Involvement

    OpenAIRE

    Ömer Özbudak; Ahmet Uslu; Aykut Çilli; Candan Öğüş; Canan Sezer; Tülay Özdemir

    2005-01-01

    Swyer-James (Macleod’s) syndrome (SJMS) is a rare disorder thought to be a complication of childhood infections. Unilateral hyperlucency, reduced lung volume, diminished vascular markings and bronchiectasis may be detected on radiological analysis. Bilateral involvement is rare. We present a 20-yearl-old man who was diagnosed as having bilateral SJMS by radiological analysis and ventilation-perfusion scintigraphy.

  10. School Engagement and Parental Involvement: The Case of Cross-Border Students in Singapore

    Science.gov (United States)

    Yuen, Celeste Y. M.; Cheung, Alan C. K.

    2014-01-01

    The primary purpose of this paper is to examine the mutual relationship between school engagement of cross-border students (CBS) from Malaysia in Singapore and parental involvement in education. Focus-group interviews were conducted with school personnel, CBS and their non-local counterparts to provide a comprehensive understanding of the…

  11. The involvement of citizens evaluating public security policies: Baja California’s case

    Directory of Open Access Journals (Sweden)

    Pablo Jesús González Reyes

    2003-07-01

    Full Text Available This paper emphasizes the importance of citizen involvement in the evaluation processes of public security policy in Baja California, as a revealing need of establishing new options for public management, through which relationships of mutual responsibility between society and government are enacted.

  12. A Death Involving a Fired and Deflected Bullet: A Case Report from Lyon University Institute of Forensic Science, France.

    Science.gov (United States)

    Maujean, Géraldine; Guinet, Tiphaine; Malicier, Daniel

    2016-01-01

    In case of gunshot deaths, atypical wounds can make the distinction between entrance and exit wounds harder. They may be due either to anatomical reasons or to diverse cogent ballistic arguments. The reported case pertains to a fatal hunting accident involving an expanded conical point bullet against the neck with both atypical entrance and exit wounds. Ballistic analyses including test firings allowed a better understanding of the external and internal findings. Upon premature impact with an intermediary target, the bullet experienced expansion in the formation of sharp brass petals responsible for a star-shaped entry wound. The trajectory of the deformed high energy projectile through the victim's body was then deviated by the cervical column, causing it to be tangential to the skin when exiting the body. The description of such atypical cases may benefit other experts and may assist in their investigation into similar cases.

  13. Radiative damping: a case study

    CERN Document Server

    Spohn, Herbert

    2011-01-01

    We are interested in the motion of a classical charge coupled to the Maxwell self-field and subject to a uniform external magnetic field, B. This is a physically relevant, but difficult dynamical problem, to which contributions range over more than one hundred years. Specifically, we will study the Sommerfeld-Page approximation which assumes an extended charge distribution at small velocities. The memory equation is then linear and many details become available. We discuss how the friction equation arises in the limit of "small" B and contrast this result with the standard Taylor expansion resulting in a second order equation for the velocity of the charge.

  14. Brick handling: a case study.

    Science.gov (United States)

    Webb, R D; Handyside, J

    1982-09-01

    A small change in brick dimensions resulted in an increase in the perceived work-load of men loading and unloading pallets of bricks by hand. A laboratory study indicated that the change in brick dimensions required changes in grip pattern in order to unload bricks at the same rate, moving the same number at a time. These changed grip patterns resulted in increased upper body movement, increased chest-muscle activity and higher heart rates. These differences were reflected in higher subjective ratings of fatigue. PMID:15676442

  15. Ownership and Control Structures: A Case Study

    OpenAIRE

    Apostolov, Mico

    2015-01-01

    This is a study on separation of ownership and control in Southeast Europe, and in particular it is a case study of Macedonia. For structured analysis of this case study we use the World Bank Microdata Library, specifically the Enterprise Surveys which contains firm-level data of a representative sample of economies private sectors. What we are interested in are the ties of ownership and control and whether such linkages contribute to the development of domestic firms and the overall ec...

  16. Case report 390: Tuberculous pseudotumor of the proximal end of the right tibia without obvious synovial involvement

    Energy Technology Data Exchange (ETDEWEB)

    Abdelwahab, I.F.; Present, D.A.; Klein, M.J.

    1986-11-01

    A case of osseous tuberculosis has been presented in a young black man who was known to be an addict to cocaine. An osteolytic lesion involved the proximal end of the tibia, being eccentric and subarticular in location. The knee joint spaces were intact, suggesting that no obvious involvement of the cartilages was present. Thus, neoplastic lesions such as chondroblastoma and giant cell tumor were considered in the differential diagnosis of the lesion which appeared to be benign radiologically. The lesion proved to be tuberculous in nature, with intact knee joint cartilages. A diagnosis of tuberculous 'pseudotumor' might be used aptly. (orig./SHA).

  17. Central Nervous System Involvement of T-cell Prolymphocytic Leukemia Diagnosed with Stereotactic Brain Biopsy: Case Report

    Directory of Open Access Journals (Sweden)

    Selçuk Göçmen

    2014-03-01

    Full Text Available Prolymphocytic leukemia (PLL is a generalized malignancy of the lymphoid tissue characterized by the accumulation of monoclonal lymphocytes, usually of B cell type. Involvement of the central nervous system (CNS is an extremely rare complication of T-cell prolymphocytic leukemia (T-PLL. We describe a case of T-PLL presenting with symptomatic infiltration of the brain that was histopathologically proven by stereotactic brain biopsy. We emphasize the importance of rapid diagnosis and immediate treatment for patients presenting with CNS involvement and a history of leukemia or lymphoma.

  18. Optic nerve involvement in childhood onset systemic lupus erythematosus: Three cases and a review of the literature.

    Science.gov (United States)

    Suri, D; Abujam, B; Gupta, A; Rawat, A; Saikia, B; Walker Minz, R; Gupta, V; Bansal, R; Kaushik, S; Singh, S

    2016-01-01

    The ocular system can be affected in systemic lupus erythematosus (SLE) in one third of patients. However, optic nerve involvement is relatively uncommon, but is more so in pediatric SLE patients, where it can occur in 1% of cases. We report three children with SLE who presented with optic nerve involvement. Two children had optic neuritis, with optic neuritis being the first manifestation in one child. The third child had ischaemic optic neuropathy secondary to antiphospholipid syndrome. A careful work up for SLE should be performed in every child with optic nerve disease. Prompt diagnosis and early treatment results in a better prognosis.

  19. Disseminated Cutaneous Leishmaniasis with Ocular Involvement in An Immunocompromised Patient: A Case Report

    Directory of Open Access Journals (Sweden)

    Bita Kiafar

    2013-12-01

    Full Text Available Purpose: To introduce a case of cutaneous and lid leishmaniasis in an immune suppressed woman Case report: We report an unusual clinical course of old world cutaneous leishmaniasis (OWCL in an immune suppressed 51 years old women recipient of kidney transplant. She developed disseminated cutaneous leishmaniasis (DCL with bilateral upper and lower eye lids lesions. Antimoniate compounds were not available and she did not tolerate amphotricin B. After replacing mycophenolate mofetil and cyclosporine by sirolimus, her Lesions though partially improved, were still persistent in the last visit after six months. Conclusion: Ocular leishmaniasis should be considered in the differential diagnosis of modula or ulcerative of the eyelids specially in the endormic cases.

  20. Music in context : Four case studies

    NARCIS (Netherlands)

    Randwijck, R.J.C. van

    2008-01-01

    In his thesis entitled “Music in Context. Four Case Studies”, R.J.C. van Randwijck investigates the context in which music has been created. It is a search in Four Case Studies, approaching four pieces of music from the context in which they were written in order to understand their meaning. The inv

  1. Case studies of steel structure failures

    Directory of Open Access Journals (Sweden)

    P. Bernasovský

    2010-01-01

    Full Text Available The contribution deals with some case studies of steel structure failures, which happened in Slovakia a few years ago. Features of cracking are illustrated on real cases of breakdowns in the transmission gas pipelines, at the cement works and in the petrochemical indus-try. All failures were caused by an incorrect technical approach. Possible remedial measures are proposed.

  2. Abbreviated Case Studies in Organizational Communication

    Science.gov (United States)

    Wanguri, Deloris McGee

    2005-01-01

    The cases contained within organizational communication texts are generally two to three pages, often followed by questions. These case studies are certainly useful. They generally describe events in the present, provide some type of organizational context, include first-hand data, include a record of what people say and think, develop a…

  3. Mining Product Data Models: A Case Study

    OpenAIRE

    Cristina-Claudia DOLEAN

    2014-01-01

    This paper presents two case studies used to prove the validity of some data-flow mining algorithms. We proposed the data-flow mining algorithms because most part of mining algorithms focuses on the control-flow perspective. First case study uses event logs generated by an ERP system (Navision) after we set several trackers on the data elements needed in the process analyzed; while the second case study uses the event logs generated by YAWL system. We offered a general solution of data-flow m...

  4. Case study on printed matter

    DEFF Research Database (Denmark)

    Introduction Existing product Life Cycle Assessments (LCA’s) on offset printed matter all point at paper as the overall dominating contributor to the impacts from the life-cycle of this category of products. This dominating role of paper is primarily founded in the energy-related impact categories...... global warming, acidification and nutrification. The studies focus on energy consumption including the emissions and impact categories related to energy. The chemical-related impact categories comprising ecotoxicity and human toxicity are not included at all or only to a limited degree. In this paper we...... include these chemical-related impact categories by making use of some of the newest knowledge about emissions from the production at the printing industry combined with knowledge about the composition of the printing materials used during the production of offset printed matter. This paper is based...

  5. Idiopathic retroperitoneal fibrosis involving a unilateral renal sinus: A case report and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seul Bi; Yoon, Jung Hee; Kim, Seung Ho; Lee, Ye Daum; Kim, Suk Jung; Lim, Yun Jung; Jung, Hyun Kyung; Lee, Jin Soo [Dept. of Radiology, Haeundae Paik Hospital, Inje University College of Medicine, Busan (Korea, Republic of)

    2016-06-15

    Idiopathic retroperitoneal fibrosis (RPF) is a rare disease entity and its etiology is uncertain. We report two similar cases which showed an uncommon presentation of idiopathic RPF. A 66-year-old woman and an 80-year-old man presented with incidental findings of left renal pelvic mass-like lesions. Computed tomography revealed a soft tissue density mass replacing the left renal pelvis, which was suspicious for renal pelvic cancer, and the diagnosis of idiopathic RPF was surgically confirmed. To the best of our knowledge, a few cases of idiopathic RPF presenting with features of a localized unilateral renal pelvic mass mimicking renal pelvic cancer have been reported.

  6. UNILATERAL CYSTIC RENAL DISEASE WITH DIFFUSE INVOLVEMENT OF KIDNEY: A CASE REPORT

    OpenAIRE

    Manoj; De, Nabanita; Gautam

    2014-01-01

    : Unilateral renal cystic disease (URCD) is a rare, non-familial, non-progressive, unilateral cystic disorder of the kidney that is not associated with cysts or disorders in other organs and it is not related to other genetic cystic diseases. Only a few cases have been reported in the literature. We report a case of URCD in an adult male 49 years of age. Absence of a family history, benign clinical course and limitation of the disease to one kidney distinguish this condition f...

  7. Case study in professionally-oriented training

    Directory of Open Access Journals (Sweden)

    Valitov Shamil M.

    2016-01-01

    Full Text Available Modern educational technologies are based on competence approach and focus on the future professional activity. Case study is one of the most significant technologies in modern higher education. The basic concepts used in the case study method are a “situation” and an “analysis”, as well as their derivative - “analysis of the situation”. The case study method of is one of the best tools for gaining experience, as it investigates practical situations that occur in managerial job. It combines theoretical knowledge with the analysis of the actual practical experience in accordance with a major. Doing case studies students read the description of the situation and offer divergent projects of managerial decisions that could be used by real managers dealing with the problem posed by the case study author. Answers to the questions posed in the case description are not given, as a rule, since the main purpose in the case analysis is to organize a discussion in the classroom or provoke speculations of those who do the self-study.

  8. Different strategies do not moderate primary motor cortex involvement in mental rotation: a TMS study

    Directory of Open Access Journals (Sweden)

    Koeneke Susan

    2007-08-01

    Full Text Available Abstract Background Regions of the dorsal visual stream are known to play an essential role during the process of mental rotation. The functional role of the primary motor cortex (M1 in mental rotation is however less clear. It has been suggested that the strategy used to mentally rotate objects determines M1 involvement. Based on the strategy hypothesis that distinguishes between an internal and an external strategy, our study was designed to specifically test the relation between strategy and M1 activity. Methods Twenty-two subjects were asked to participate in a standard mental rotation task. We used specific picture stimuli that were supposed to trigger either the internal (e.g. pictures of hands or tools or the external strategy (e.g. pictures of houses or abstract figures. The strategy hypothesis predicts an involvement of M1 only in case of stimuli triggering the internal strategy (imagine grasping and rotating the object by oneself. Single-pulse Transcranial Magnetic Stimulation (TMS was employed to quantify M1 activity during task performance by measuring Motor Evoked Potentials (MEPs at the right hand muscle. Results Contrary to the strategy hypothesis, we found no interaction between stimulus category and corticospinal excitability. Instead, corticospinal excitability was generally increased compared with a resting baseline although subjects indicated more frequent use of the external strategy for all object categories. Conclusion This finding suggests that M1 involvement is not exclusively linked with the use of the internal strategy but rather directly with the process of mental rotation. Alternatively, our results might support the hypothesis that M1 is active due to a 'spill-over' effect from adjacent brain regions.

  9. Energy Audit: A Case Study

    Directory of Open Access Journals (Sweden)

    Sanjay Kumar

    2013-06-01

    Full Text Available This India is the Fifth largest producer of Electricalenergy in the world. Despite such achievements the gapbetween demand and supply of electrical energy is increasingevery year and power sector is highly capital – intensive. Thusthe deficit in installed capacity was nearly 10000MWper year.So the gap between demand and supply is continuouslyincreasing day by day. An energy audit is a study of a plant orfacility to determine how and where energy is used and toidentify methods for energy savings. The opportunities lie inthe use of existing renewable energy technologies, greaterefforts at energy efficiency and the dissemination of thesetechnologies and options. This thesis provides an overview of ageneral energy conservation measures (ECMs that can becommonly recommended for NIT Hamirpur. It should be notedthat the Energy auidut presented in this paper does not pretendto be exhaustive nor comprehensive. It provides merely toindicate some of the options that energy auditor can considerwhen performing an analysis of this institute. Energyconservation and exploration of new energy avenues are thewell accepted solution to fulfil the demand in future. The totalcost of energy plays a vital role in determining the product costof a commodity. Therefore the identification of potential energysavings and implementation for a given institutional facility isunimportant to ensure its competitive advantage over otherinstitute. This paper work presents such energy saving methodsin a methodological approach, experienced during a detailedenergy audit of NIT Hamirpur.

  10. Antiphospholipid syndrome: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Davies, T. [Royal Adelaide Hospital, Adelaide, SA (Australia). Department of Nuclear Medicine

    1998-03-01

    Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient``s high risk of strokes and hemorrhaging prompted investigation by a {sup 99}mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome.

  11. Delay in diagnosis of generalized miliary tuberculosis with osseo-articular involvement: a case report

    Directory of Open Access Journals (Sweden)

    Atukorala Inoshi

    2011-10-01

    Full Text Available Abstract Introduction Diagnosis of atypical tuberculosis is difficult. Therefore, it is important that physicians are aware of rare presentations of tuberculosis to avoid diagnostic delays. Case presentation We present the case of a 17-year-old Sri Lankan man who presented to our facility with an ill-defined large induration over the skin of his left buttock and thigh. A cause could not be found despite extensive investigations. He also complained of chronic knee pain, but this was not investigated further at the time due to spontaneous resolution. Three years later his knee disease flared up again, with pain, swelling and restriction of movement. A synovial biopsy was suggestive of tuberculosis. He was started on antituberculosis therapy, to which he responded well. Our patient was asymptomatic two months after completion of therapy without any subsequent flare-ups. A chest roentgenogram taken on his second presentation showed evidence of tuberculosis sequelae in his lungs. The most likely diagnosis for the buttock and thigh swelling, when considering the entire clinical picture, is a tuberculous abscess. The constellation of skin and skeletal symptoms and pulmonary tuberculosis is a rare occurrence in an immunocompetent individual, but cases have been reported. Conclusions This case demonstrates the different presentations and the diagnostic difficulties posed by atypical manifestations of tuberculosis. It also demonstrates the value of maintaining a high degree of suspicion in endemic areas, even in the absence of microbiological evidence.

  12. Involving citizens in public decision making: the case of participatory budgeting in Lithuania

    OpenAIRE

    Liucija Birskyte

    2013-01-01

    In times of increasing public distrust in government and its institutions, engaging the public in decision making may strengthen democracy as well as result in a more effective allocation of scarce public resources. Participatory budgeting has started in Brazil and spread around the world but is a new concept in some countries. The objective of this paper is to reveal the current situation of attempts to involve the public in making decisions on budget allocations in Lithuanian municipalities...

  13. A Case of Swyer-James (Macleod’s Syndrome with Bilateral Involvement

    Directory of Open Access Journals (Sweden)

    Ömer Özbudak

    2005-01-01

    Full Text Available Swyer-James (Macleod’s syndrome (SJMS is a rare disorder thought to be a complication of childhood infections. Unilateral hyperlucency, reduced lung volume, diminished vascular markings and bronchiectasis may be detected on radiological analysis. Bilateral involvement is rare. We present a 20-yearl-old man who was diagnosed as having bilateral SJMS by radiological analysis and ventilation-perfusion scintigraphy.

  14. A T-cell prolymphocytic leukemia case with central nervous system involvement

    Science.gov (United States)

    Malkan, Umit Yavuz; Gunes, Gursel; Yayar, Okan; Demiroglu, Haluk; Yesilirmak, Aysun; Uner, Aysegul

    2015-01-01

    T-cell prolymphocytic leukemia (T-PLL) is an aggressive mature T cell neoplasm that typically involves peripheral blood, bone marrow, lymph nodes and spleen. It is a rare disease that comprises 2-5% of mature lymphocytic leukemia in adults. Here we present a T-PLL patient with CNS involvement. A 74-year-old man admitted to a hospital in April 2014 with vomiting. He was diagnosed as chronic lymphocytic leukemia (CLL) and R-CVP (Rituximab, cyclophosphamide, vincristine and prednisolone) chemotherapy protocol was started. After the first two cycles of chemotherapy, the patient’s mental functions improved. However after the 3rd cycle of chemotherapy was given in July 2014 the general situation of the patient deteriorated and ptosis of the left eye and facial paralysis developed. Then the patient was referred to our medical center. An MR of the brain revealed linear contrast enhancement around the bilateral 3rd, 7th and 8th cranial nerves which indicated cranial involvement by the lymphoproliferative process (Figure 1). Cerebrospinal fluid cytological examination confirmed the diagnosis. Based on these and bone marrow aspiration and biopsy findings a diagnosis of T-PLL was rendered (Figure 3). In September 2014 the patient died suddenly due to a cardiac arrest. Differential diagnosis is very important in T-PLL. Both T-PLL and chronic lymphocytic leukemia (CLL) may present with splenomegaly and lymphocytosis as well as circulating prolymphocytes in blood. Typical CLL cells are like mature lymphocytes with dense nucleus and aggregated chromatin. To conclude, CNS involvement in T-PLL is a rare finding and differential diagnosis of T-PLL is very important. PMID:26550397

  15. Understanding International Similarities and Differences in Corporate Community Involvement: The Case of Capital One

    OpenAIRE

    Amerman, Taylor

    2012-01-01

    Corporate Social Responsibility (CSR) is a highly dynamic and contestable concept in today’s global marketplace (Matten & Moon, 2004). One area of CSR is Corporate Community Involvement (CCI) or a “corporation’s engagement with local communities, special interest groups and issues of concern, above and beyond the day-to-day operations, often working in partnership with not-for-profit organizations” (Tuffrey, 1998). CCI drives business decision-making to make a significant and sustainable impa...

  16. Aspergillus Spondylitis involving the Cervico-Thoraco-Lumbar Spine in an Immunocompromised Patient: a Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Son, Jeong-Min; Jee, Won-Hee; Jung, Chan-Kwon; Kim, Sang-Il; Ha, Kee-Yong [The Catholic University of Korea, Seoul (Korea, Republic of)

    2007-10-15

    Aspergillosis is a rare cause of spondylitis. Moreover, early diagnosis by MR imaging and adequate treatment can prevent the serious complications of fungal infection. To our knowledge, the MR findings of multilevel aspergillus spondylitis in the cervico-thoraco-lumbar spine have not been previously described. Here, we report the MR findings of aspergillus spondylitis involving the cervical, thoracic, and lumbar spine in a liver transplant recipient. spergillosis is a rare cause of spondylitis, and early diagnosis by MR imaging and adequate treatment are essential for a good outcome. Although the MR findings of bacterial spondylitis have been fully described, the findings of aspergillus spondylitis have been rarely described, and to the best of our knowledge multilevel involvement of cervico-thoraco-lumbar spine has not been previously reported. Here, we report the MR imaging findings of aspergillus spondylitis involving the cervico-thoraco-lumbar spine in a liver transplant recipient. In conclusion, aspergillus spondylitis should be considered in the differential diagnosis of immunocompromised patients with MR findings resembling those of tuberculous spondylitis.

  17. CONDITIONS THAT INCREASE DRUG MARKET INVOLVEMENT: THE INVITATIONAL EDGE AND THE CASE OF MEXICANS IN SOUTH TEXAS.

    Science.gov (United States)

    Valdez, Avelardo; Kaplan, Charles

    2007-01-01

    Research on drug trafficking has not been able to discern the exact nature of illegal drug markets and the relationship between their individual and group participants. This article delineates the role of Mexican immigrants and Mexican-American participants involved in the stratified drug market of South Texas. This article synthesizes ethnographic materials drawn from two previous National Institute on Drug Abuse (NIDA) studies in order identify the different types of drug distribution behaviors that occur within the groups, the differentiated roles of individuals, the organizational framework, and most significantly, the processes that link market participants to others outside of the drug market. This illegal behavior can be interpreted as an adaptive mechanism that is a direct response to the marginal economic status imposed by macro socio-economical background factors. As well, we conclude that the specific foreground factors of the opportunities offered by the context, culture, and proximity of the U.S./Mexico border and invitational edges explain this behavior. There are both parallels and particular differences between the South Texas case and the structuring and functioning of informal legal and illegal markets that are characteristic of other economically disadvantaged communities. PMID:21218142

  18. Towards More Case Study Research in Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Tom Duxbury

    2012-03-01

    Full Text Available Entrepreneurship as an emerging discipline has made good strides, but according to some, has fallen short of bringing its theory and literature up to the standards of others in the management sciences. Rich with the descriptive detail needed for insightful theory building in entrepreneurship, scholars have called for more case study research, particularly those incorporating non-retrospective and longitudinal observations. At the same time however, it has become rare to find such research published in A-level journals dedicated to entrepreneurship. A survey presented here of major entrepreneurship journals over the past six years revealed a publication rate of only 3% using the case study method. This presents a major impediment for developing fresh research in this field based upon the study of real cases. The author explores how the case study method has been applied to entrepreneurship research and provides recommendations for improved publication rates.

  19. Explaining governmental involvement in home care across Europe: an international comparative study.

    NARCIS (Netherlands)

    Genet, N.; Kroneman, M.; Boerma, W.G.W.

    2013-01-01

    The involvement of governments in the home care sector strongly varies across Europe. This study aims to explain the differences through the conditions for the involvement of informal care and governments in society; wealth and the demographic structure. As this study could combine qualitative data

  20. Cardiac involvement in diphtheria: Study from a tertiary referral infectious disease hospital

    Directory of Open Access Journals (Sweden)

    Alakes Kumar Kole

    2012-01-01

    Full Text Available Background: Diphtheria is still a fatal disease even in the era of universal immunization. Diphtheria myocarditis, one of the serious complications of respiratory diphtheria may cause death if not recognized and treated properly. Aims and Objectives: To determine the outcomes of cardiac involvement in respiratory diphtheria. Materials and Methods: One hundred (n = 100 patients with respiratory tract diphtheria were evaluated in respect to cardiac involvement. All patients were closely monitored for a minimum period of 4-6 weeks from the onset of respiratory symptoms. Continuous ECG monitoring including blood biochemistry (SGOT, CPK-MB, and Troponin-T were done in each case. Results : The most common symptoms were throat pain seen in 94 cases, palpitation in 56 cases, bull neck in 40 cases, shortness of breath in 12 cases, fever in 9 cases, and nasal regurgitation in 8 cases. Most common complication observed was myocarditis seen in 70 patients and majority of patients (60 were asymptomatic. The ECG changes were T wave inversion in 54 patients, inappropriate sinus tachycardia in 38 patients, ST segment depression in precordial leads in 8 patients, Mobitz type II block in 6 patients, Mobitz type I block in 4 patients, RBBB in 4 patients, multiple atrial ectopics in 4 patients, and sinus bradycardia in 2 patients. A total number of five patients died. Conclusions: Myocarditis was commonest and serious complication of respiratory diphtheria. Increase in vaccination coverage and improvement of socioeconomic status are all effective preventive measures to reduce the incidence of diphtheria.

  1. Educational Potential of Case-Study Technology

    OpenAIRE

    Fedorinova, Zoya Vladimirovna; Vorobyeva, Viktoriya Vladimirovna; Malyanova, Marina

    2015-01-01

    This article presents the results of phenomenological and typological analysis of case-study technology educational potential. The definition “educational potential of case-study technology” is given, the main characteristics of which are changed in communication and collaborative activity quality, appearance of educational initiatives, change of participants’ position in learning process, formation of “collective subject” in collaborative activity, increase of learning (subject) results. Dep...

  2. A case story, involving the use of maltitol, a sugar alcohol, as a cutting agent in amphetamine and cocaine powders

    Directory of Open Access Journals (Sweden)

    Reitzel Lotte Ask

    2016-06-01

    Full Text Available In a criminal case involving cutting and resale of amphetamine and cocaine in the Copenhagen area of Denmark, maltitol was used as a cutting agent. The analysis of maltitol in seizures of pure diluents as well as in amphetamine and cocaine powders was carried out using reversed-phase high performance liquid chromatography (HPLC with high-resolution (HR mass spectrometric detection. Maltitol was identified in four out of nine amphetamine samples and in five out of six cocaine samples from the case in question. The use of maltitol as a cutting agent was considered by the police as a specific marker of the particular criminal group under investigation. To support or reject this hypothesis, cocaine and amphetamine samples from a four month period after the involved persons had been arrested were evaluated, also as part of the police investigation. None of these samples contained maltitol. The work described covers the part of the case involving the department of forensic chemistry, and not the whole police investigation, but everything was done within the frames given by the police. To the best of our knowledge, this is the first report of a disaccharide polyol being used as a cutting agent for illicit drugs.

  3. Collecting Duct Renal Cell Carcinoma Found to Involve the Collecting System During Partial Nephrectomy: A Case Report

    Directory of Open Access Journals (Sweden)

    Andrew C Harbin

    2015-06-01

    Full Text Available Collecting duct carcinoma (CDC is a rare and aggressive form of renal cell carcinoma (RCC arising from the principal cells of the collecting duct.  One third of cases present with metastatic disease, but many present in a manner similar to conventional RCC or urothelial carcinoma (UC.  We discuss a case of CDC which presented as a small mass at the cortico-medullary junction, and was discovered at robotic partial nephrectomy (RPN to be grossly involving the collecting system. A 62-year-old man presented with a small renal mass suspicious for RCC, which was found on computed tomography (CT after an episode of gross hematuria.  After thorough workup, RPN was attempted; however, intraoperatively the mass was found to be involving the collecting system.  Radical nephroureterectomy was performed, and the pathology report revealed CDC.  CDC is a rare and aggressive form of RCC.  While many cases are metastatic at diagnosis, most patients present with the incidental finding of a small renal mass.  There are no reports of a CDC involving the collecting system at RPN after negative ureteroscopy preoperatively.  The adjuvant therapeutic options for CDC are limited, and long term survival is poor.    

  4. TOP-10 DATA MINING CASE STUDIES

    OpenAIRE

    GABOR MELLI; XINDONG WU; PAUL BEINAT; FRANCESCO BONCHI; LONGBING CAO; RONG DUAN; CHRISTOS FALOUTSOS; RAYID GHANI; BRENDAN KITTS; BART GOETHALS; GEOFF MCLACHLAN; JIAN PEI; ASHOK SRIVASTAVA; OSMAR ZAÏANE

    2012-01-01

    We report on the panel discussion held at the ICDM'10 conference on the top 10 data mining case studies in order to provide a snapshot of where and how data mining techniques have made significant real-world impact. The tasks covered by 10 case studies range from the detection of anomalies such as cancer, fraud, and system failures to the optimization of organizational operations, and include the automated extraction of information from unstructured sources. From the 10 cases we find that sup...

  5. Two Cases of Solitary Fibrous Tumor Involving Urinary Bladder and a Review of the Literature

    Science.gov (United States)

    Buonfiglio, Vitor Bonadia; Manzano, Joao Padua; Filippi, Renée Zon; Sadi, Marcus Vinicius

    2016-01-01

    Solitary fibrous tumor (SFT) is a rare neoplasia of mesenchymal origin, initially described in visceral pleura and lately discovered to have ubiquitous distribution. SFT of the urogenital tract is uncommon and appears to have similar morphologic features and biologic behaviors as SFTs found elsewhere. We present two new cases of SFT of the bladder and review 22 similar cases published in the literature. Due to the general indolent behavior of these lesions, a complete but organ sparing surgical excision should be considered when technically feasible. Therefore, proper identification and characterization of SFT through morphological and immunohistochemical criteria on biopsy specimens are mandatory in the differential diagnosis from other more aggressive spindle-cell tumors, thus avoiding unnecessary radical surgery.

  6. Intraosseous Neurofibroma and Concurrent Involvement of the Mandible, Maxilla and Orbit: Report of a Case

    International Nuclear Information System (INIS)

    Neurofibroma is an autosomal dominant disorder which has major criteria such as hyperpigmentation (cafe-au lait spots), cutaneous and subcutaneous tumors and bone deformities. In this report, a case of multifocal intraosseous neurofibroma in a 16-year-old male with right facial asymmetry, multiple unerupted maxillary posterior teeth and a previous history of infratemporal and orbital neurofibroma is presented. The majority of reported cases occurred in the posterior portion of the mandible and a limited number in the maxilla. Cone beam CT (CBCT) was performed for better evaluation of the extension and form of the maxillary and mandibular lesions. This report presents a rare situation of simultaneous peripheral neurofibromatosis (NF) and multifocal intraosseous NF in the mandible, maxilla and orbits and also focuses on advanced imaging findings of bony and soft tissue neurofibroma

  7. Systemic panca-associated vasculitis with central nervous involvement causing recurrent myelitis: case report

    Directory of Open Access Journals (Sweden)

    Bull Matthew D

    2010-11-01

    Full Text Available Abstract Background We report on the case of an established perinuclear antineutrophil cytoplasmic antibody (pANCA associated renal vasculitis being treated with prednisolone and rituximab, where the patient presented with leg weakness, urinary and faecal incontinence and buttock pain consistent with transverse myelitis. Case presentation The patient underwent MRI scanning showing patchy cord enhancement from T10 to the conus, which was suggestive of a cord malignancy. Prior to a cord biopsy, he was treated with steroids and a repeat MRI showed resolution of the original lesion with a new similar lesion from C7 to T3. Conclusions He made a marked recovery after further treatment with high dose steroids and plasma exchange.

  8. A Case of Swyer Syndrome Associated with Advanced Gonadal Dysgerminoma Involving Long Survival

    OpenAIRE

    Da Silva Rios, Salete; Monteiro, Isabella Christina Mazzaro; Braz dos Santos, Larissa Gonçalves; Caldas, Natasha Garcia; Chen, Ana Carolina Rios; Chen, Juliana Rios; Silva, Helena Spindola Camargo

    2015-01-01

    Swyer syndrome is caused by abnormal sex differentiation during the embryonic period, resulting in incomplete intrauterine masculinization and undifferentiated gonads. The current case report describes a patient with Swyer syndrome associated with stage 3 gonadal dysgerminoma who has survived for 23 years. At age 18, this patient sought assistance for primary amenorrhea from the Gynecological Services Department of the University of Brasília Hospital. A physical examination revealed that the ...

  9. Emerging acute Chagas Disease in Amazonian Brazil: case reports with serious cardiac involvement

    OpenAIRE

    Ana Yecê das Neves Pinto; Sebastião Aldo da Silva Valente; Vera da Costa Valente

    2004-01-01

    Four cases of serious cardiac attacks by autochthonous Trypanosoma cruzi infection from the Brazilian Amazon are reported; three of them occurred in micro-epidemic episodes. The manifestations included sudden fever, myalgia, dyspnea and signs of heart failure. Diagnosis was confirmed by specific exams, especially QBC (Quantitative Buffy Coat) and natural xenodiagnosis. Despite treatment with benznidazol, three patients died with serious myocarditis, renal failure and cardiac tamponade. The au...

  10. ED-12WIDESPREAD SYSTEMIC METASTASES FROM MEDULLOBLASTOMA WITHOUT EVIDENCE OF ACTIVE CNS INVOLVEMENT: A CASE SERIES

    OpenAIRE

    Kumthekar, Priya; Singh, Simran; Smiley, Natasha Pillay; Lulla, Rishi

    2014-01-01

    This case series describes two patients with previously treated medulloblastoma who present with systemic metastases without evidence of central nervous system (CNS) disease. Patient #1 is male who presented at age 29 with pathology confirmed medulloblastoma treated with complete surgical resection followed by radiation (36 Gy craniospinal plus posterior fossa boost). Subsequently, he received cisplatin, cytoxan, and vincristine. One year later, he developed back pain and urinary retention. I...

  11. Cerebellar involvement that occurred during treatment of Legionella pneumonia: A case report

    Directory of Open Access Journals (Sweden)

    Ozlem Alici

    2013-06-01

    Full Text Available Legionnaires’ disease can appear with different levels of severity. A case of a previously healthy lady with communityacquiredpneumonia who progressed to severe acute respiratory distress syndrome and developed cerebellar dysfunctionis reported. In patients presenting with neurological symptoms after an episode of pneumonia, Legionella infectionshould be considered. J Microbiol Infect Dis 2013; 3(2: 83-85Key words: Legionella, cerebellar dysfunction, dysarthria, ataxia

  12. Cases of Review and Adjudication and Lawsuit Involving Trademark Composed of Combination of Colours

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Case 1 The English applicant, the Standard Chartered PLC, filed, on 18 April 2002, an application with the Trademark Office for registration of a device trademark (See Fig. 1 below; hereinafter referred to as the trademark in point) in goods of class 16 of the International Classification, such as "paper, card board, book, magazine, and stationery". The applicant stated in the application that the trademark in point was one composed of combination of colours. Upon examination, the Trademark Office issued...

  13. Her-2 Positive Gastric Cancer Presented with Thrombocytopenia and Skin Involvement: A Case Report

    OpenAIRE

    Deniz Arslan; Mukremin Uysal; Ali Murat Tatlı; Seyda Gunduz; Sema Sezgin Goksu; Cumhur İbrahim Başsorgun; Hasan Senol Coskun; Hakan Bozcuk; Burhan Savaş

    2014-01-01

    Gastric cancer is the 5th most frequent cancer around the world and the 3rd most frequent reason of deaths due to cancer. Every year, about 1 million new cases are taking place, with varying geographical distribution. Gastric cancer is often metastatic to liver, lungs, and bones in hematogenous way, to peripheral lymph nodes in lymphogenous way, and to peripheral tissues in adjacency way, yet bone marrow (BM) and cutaneous metastasis are quite seldom. Pancytopenia is a more frequent finding i...

  14. Possible vitreous involvement in a case with rapidly progressing choroidal neovascularization

    Directory of Open Access Journals (Sweden)

    Masayuki Hata

    2012-01-01

    Full Text Available A 65-year-old man with subfoveal choroidal neovascularization (CNV underwent photodynamic therapy (PDT. Despite the sequential treatments, the CNV grew larger and finally penetrated the retina. Vitreous adhesion was observed at the edge of the supraretinal fibrotic tissue. The case highlighted the possible unexpected side-effect of PDT. The upregulation of the vascular endothelial growth factor or the enhanced vitreous traction was considered to be responsible for the event.

  15. Recurrent malignant otitis externa with multiple cranial nerve involvement: A case report

    Directory of Open Access Journals (Sweden)

    Đerić Dragoslava

    2016-01-01

    Full Text Available Introduction. Necrotizing otitis externa is a rare but conditionally fatal infection of external auditory canal with extension to deep soft tissue and bones, resulting in necrosis and osteomyelitis of the temporal bone and scull base. This condition is also known as malignant otitis due to an aggressive behavior and poor treatment response. Early diagnosis of malignant otitis is a difficult challenge. We present an illustrative case of necrotizing otitis externa and suggest some strategies to avoid diagnostic and treatment pitfalls. Case Outline. A 70-year-old patient presented with signs of malignant otitis externa, complicated by peripheral facial palsy. Adequate diagnostic and treatment procedures were performed with clinical signs of resolution. The recurrence of malignant infection had presented three months after previous infection with multiple cranial nerve neuropathies and signs of jugular vein and lateral sinus thrombosis. An aggressive antibiotic treatment and surgery were carried out, followed by substantial recovery of the patient and complete restoration of cranial nerves’ functions. Conclusion. Necrotizing otitis externa is a serious condition with uncertain prognosis. The suspicion of malignant external otitis should be raised in cases of resistance to topical treatment, especially in patient with predisposing factors. Evidence-based guideline for necrotizing otitis externa still doesn’t exist and treatment protocol should be adjusted to individual presentation of each patient.

  16. Cardiac involvement and its complications about three cases of severe scorpion envenomation.

    Science.gov (United States)

    Aboumaâd, B; Tiger, A; Khattabi, A; Soulaymani, R; Lahssaini, M; Benhassain, S M; Iba, N

    2014-02-01

    For several decades, Morocco is confronted to medico-social problem of scorpion stings and envenomations. In 2009, epidemiological data established by the Poison Control Center recorded 29,816 stung patients, with an incidence of 1.1‰ and a fatality rate of 0.18%. The neurotoxins from scorpion venom are potent activators of the autonomic nervous system resulting a physiopathological disorder of vital systems. The most serious clinical manifestations are neurotoxic effects, pulmonary edema and cardiovascular distress. This present work reports the cases of three children (4 years and 6 months, 8 months and 15 days, 4 years), hospitalized in intensive care for an envenomation by Androctonus mauritanicus (the most fatal scorpion specie). The children presented cardiac dysfunction where pulmonary edema and state of shock were complications resultants. Two cases survived after supportive and symptomatic treatment based on dobutamine as primordial treatment in cardiovascular and pulmonary correction and other drugs. The third case died. The objective of this work was to detect the limit of the effectiveness of symptomatic treatment during a severe scorpion envenomation. PMID:24316266

  17. Rosai Dorfman disease: case with extensive dural involvement and cerebrospinal fluid pleocytosis.

    Science.gov (United States)

    Nalini, Atchayaram; Jitender, Saini; Anantaram, Gudipati; Santosh, Vani

    2012-03-15

    We report a young adult man who presented with chronic raised intracranial tension features and unusually progressive bilateral visual and hearing impairment of 18 months duration. MR imaging showed extensive dural involvement and contiguous orbital and spinal disease. Cerebrospinal fluid demonstrated persistent high lymphocytic pleocytosis. Dural biopsy obtained from posterior cervical approach with C1 arch excision and meningeal biopsy revealed features of classical of Rosai-Dorfman disease. Histiocytes were strongly positive for CD-68 and S-100 proteins. The illness relentlessly progressed with patient developing total deafness and near total blindness at last follow-up. PMID:22029938

  18. Experiences in methods to involve key players in planning protective actions in a case of nuclear accident

    International Nuclear Information System (INIS)

    Full text: Openness, transparency and key players participation are all important for balanced decision making in public issues. The emergency exercises involve commonly representatives from various sectors of the society to increase competence and build links for communication and coordination. A different approach has been a set of meetings where the key players aimed to plan comprehensive set of generic protective actions. The approach of this work was to develop methods and techniques to evaluate systematically and comprehensively protective action strategies. This was done in a way that all key players' concerns and issues related to decisions on protective actions could be aggregated openly and equally. We have developed and tested an approach called facilitated workshop based an theory of decision analysis. The work builds on case studies in which it was assumed that a hypothetical accident at a nuclear power plant had led to a release of considerable amounts of radionuclides and therefore various types of protective actions should be considered. Altogether six workshops were organized where all key players were represented, i.e., authorities, expert organizations, industry and producers. The participants were those who are responsible for preparing advice or making presentations of matters to those responsible for formal decision-making. Many preparatory meetings were held with various experts. It was seen essential that the setup followed strictly the decision-making process the participants are accustomed with. The realistic nature and the disciplined process of a facilitated workshop, and committed to decision-making yielded insight on what information should be collected or studied. Information should be in the proper form needed in decision-making. For example, the study revealed the need to further develop methods to assess the radiological and cost implications of different countermeasures realistically. In order to provide consequence assessments

  19. Handling ethical, legal and social issues in birth cohort studies involving genetic research: responses from studies in six countries

    OpenAIRE

    LeGrandeur Jane; Ries Nola M; Caulfield Timothy

    2010-01-01

    Abstract Background Research involving minors has been the subject of much ethical debate. The growing number of longitudinal, pediatric studies that involve genetic research present even more complex challenges to ensure appropriate protection of children and families as research participants. Long-term studies with a genetic component involve collection, retention and use of biological samples and personal information over many years. Cohort studies may be established to study specific cond...

  20. Predicting Students Drop Out: A Case Study

    Science.gov (United States)

    Dekker, Gerben W.; Pechenizkiy, Mykola; Vleeshouwers, Jan M.

    2009-01-01

    The monitoring and support of university freshmen is considered very important at many educational institutions. In this paper we describe the results of the educational data mining case study aimed at predicting the Electrical Engineering (EE) students drop out after the first semester of their studies or even before they enter the study program…

  1. Case Study: Giant Cell Arteritis with Vertebral Artery Stenosis

    OpenAIRE

    Daniel Chomlak, R.; Ghazanfari, Farshad; Datta, Mineesh

    2016-01-01

    In giant cell arteritis (GCA), involvement of the vertebral arteries is rare with reported rates of 3%–4% for ischemic events secondary to vertebral artery stenosis or occlusion for those patients with GCA. This case study describes a patient who initially presented with acute onset of vertigo but was also found to have transient, side-alternating upper limb neurological findings. While initial imaging showed no vascular abnormalities, it was not until GCA was eventually confirmed with a temp...

  2. Software war stories case studies in software management

    CERN Document Server

    Reifer, Donald J

    2014-01-01

    This book provides readers with practical advice on how to handle the many issues that can arise as a software project unfolds. The book uses twelve case studies to communicate lessons learned addressing such issues as they occur in government, industrial and academic settings. These cases focus on addressing the things that can be done to establish and meet reasonable expectations.  Such corrective actions often involve more than just dealing with project issues.  For example, software practitioners may have to address obstacles placed in their way by procurement, organizational procedures an

  3. The accordion sign at CT: report of a case of Crohn's disease with diffuse colonic involvement

    International Nuclear Information System (INIS)

    The accordion sign is a finding that could be seen on CT scans of the abdomen in patients who have received oral contrast material. Initially, it was described as a sign specific of Clostridium difficile colitis, but it is also reported to represent a sign of diffuse colonic edema of several other etiologies. We report a case of a patient with Crohn's pancolitis whose abdominal CT scan presented the accordion sign throughout the entire large bowel together with signs of Crohn's disease of the small bowel. (orig.)

  4. Pediatric fibromatosis involving mandible: case reportand a five-year post-operative follow-up

    Directory of Open Access Journals (Sweden)

    Vilson Lacerda Brasileiro Junior

    2013-06-01

    Full Text Available Extra-abdominal fibromatosis is a benign fibrous neoplasm of locally aggressive behavior. Surgical excision with a wide margin is the treatment of choice. The aim of the present work is to report the case of fibromatosis in an 11-year-old melanodermic patient, who showed swelling in the area of the right mandible. Conservative surgery was performed based on the initial histopathological diagnosis of benign lesion suggestive of neural origin. The new anatomopathological examination of the surgical specimen was compatible with fibromatosis. The patient is still under periodic observation as part of the five-year surgical follow-up, showing no signs of recurrence.

  5. Dirofilariasis involving the oral cavity: report of the first case from South America

    Directory of Open Access Journals (Sweden)

    Laudenice Lucena Pereira

    2015-06-01

    Full Text Available Oral dirofilariasis is very rare with non-specific clinical manifestations. Here, we report the case of a 65-year-old South American woman with a submucosal nodule on her right buccal mucosa. The nodule was slightly tender and painful. Differential diagnoses included mesenchymal (lipoma or fibrolipoma, solitary fibrous tumor, and neurofibroma or glandular benign tumors (pleomorphic adenoma with secondary infections. We performed excisional biopsy. A histopathological examination revealed a dense fibrous capsule and a single female filarial worm showing double uterus appearance, neural plaque, well-developed musculature and intestinal apparatus. Dirofilariasis was diagnosed, and the patient was followed-up for 12 months without recurrence.

  6. Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review

    Directory of Open Access Journals (Sweden)

    Reza Ashrafi

    2011-01-01

    Full Text Available Background. We present the case of a 35-year-old gentleman who presented with an aggressive cardiomyopathy with normal coronary arteries. He was later diagnosed with systemic lupus-related cardiomyopathy. Methods. We undertook an extensive review of the literature regarding cardiac manifestations of lupus and used over 100 journals to identify the key points in pathology, diagnosis, and treatment. Results. We have shown that cardiac lupus can be rapidly progressive and, unless treated early, can have severe consequences. The predominant pathologies are immune complex and accelerated atherosclerosis drive. Treatment comprised of high-level immunosuppression.

  7. Thyroid Eye Disease With Significant Levator Involvement and Ptosis: A Case Report.

    Science.gov (United States)

    Scruggs, Ryan T; Black, Evan H

    2015-01-01

    A case of an 87-year-old woman with a history of Graves disease presenting with a 5-year history of severe ptosis and very poor levator function of the left side is presented. MRI revealed marked enlargement of all extraocular muscles and significant enlargement of the left levator muscle. Given the patient's age and atypical presentation of thyroid eye disease (TED), she was taken to the operating room for biopsy and ptosis repair with frontalis suspension. Histopathological analysis revealed chronic inflammation and fibrosis consistent with Graves disease.

  8. Service Innovation Involved by Employees and Customers:From Conceptual Model to an IT Service Case

    Institute of Scientific and Technical Information of China (English)

    LIU De-wen; LU Ruo-yu

    2006-01-01

    With the service industry and information technology developing, Service innovation occurs continually in business today. It is important for service firms to understand the service's business and process;customer knowledge including needs, expectations and experiences.However, employees are key factor to collect the customer's advice. At the same time, employees may organize customers for the new service. So, the integration of employees and customers will help service firm in the way of developing a new service and upgrading a service. The paper describes some models to explain the relation based on some literatures and give some advices for service firms. At last, we introduce an IT service case

  9. A generalized model to estimate the statistical power in mitochondrial disease studies involving 2×k tables.

    Directory of Open Access Journals (Sweden)

    Jacobo Pardo-Seco

    Full Text Available BACKGROUND: Mitochondrial DNA (mtDNA variation (i.e. haplogroups has been analyzed in regards to a number of multifactorial diseases. The statistical power of a case-control study determines the a priori probability to reject the null hypothesis of homogeneity between cases and controls. METHODS/PRINCIPAL FINDINGS: We critically review previous approaches to the estimation of the statistical power based on the restricted scenario where the number of cases equals the number of controls, and propose a methodology that broadens procedures to more general situations. We developed statistical procedures that consider different disease scenarios, variable sample sizes in cases and controls, and variable number of haplogroups and effect sizes. The results indicate that the statistical power of a particular study can improve substantially by increasing the number of controls with respect to cases. In the opposite direction, the power decreases substantially when testing a growing number of haplogroups. We developed mitPower (http://bioinformatics.cesga.es/mitpower/, a web-based interface that implements the new statistical procedures and allows for the computation of the a priori statistical power in variable scenarios of case-control study designs, or e.g. the number of controls needed to reach fixed effect sizes. CONCLUSIONS/SIGNIFICANCE: The present study provides with statistical procedures for the computation of statistical power in common as well as complex case-control study designs involving 2×k tables, with special application (but not exclusive to mtDNA studies. In order to reach a wide range of researchers, we also provide a friendly web-based tool--mitPower--that can be used in both retrospective and prospective case-control disease studies.

  10. Palmoplantar Dermatoses- A Clinical Study of 300 Cases

    Science.gov (United States)

    Rajashekhar, Nadiga; Gejje, Somashekar

    2016-01-01

    Introduction Dermatoses affecting palms and soles are among the most difficult of all dermatological therapeutic problems. Many previous studies have focused on the specific diseases of palmoplantar dermatoses. However, none of them have included a comprehensive study of palmoplantar dermatoses. Aims: To study the epidemiological aspects like age distribution, sex distribution, the dermatoses affecting the palms & soles and the frequency of involvement of palms, soles or both palms & soles, in patient with palmoplantar dermatoses. Materials and Methods This cross sectional study was conducted in the Department of Dermatology between October 2011 to September 2013. First 300 cases attending the department of dermatology primarily with complaints pertaining to palms and soles were enrolled in the study. After taking consent a detailed history and clinical examination pertaining to the aim of the study was recorded and analysed, which included inspection of morphology and distribution of lesions and palpation of any swelling. Direct microscopic examination of scrapings, wet mounted with 10% potassium hydroxide was done for cases with scaly lesions. Those who had a pustule, gram staining was done. Patch testing using Indian Standard Battery Series was done for those cases of eczema. A sample for biopsy was taken when diagnosis could not be arrived clinically, and subjected to histopathological examination. Results In our study of 300 patients with palmoplantar dermatoses, 164 were females and 136 were males, the ratio observed being 1.2:1. The peak incidence was found in the age group 21-30 years, with 41 females (25%) and 35 males (25.7%). Most frequently affected individuals in this study were housewives (30%). The most common five diseases of palmoplantar dermatoses were palmoplantar psoriasis (20.7%), moniliasis (19%), palmoplantar hyperhidrosis (7%), keratolysis exfoliativa (6%) and pitted keratolysis (6%). Majority of patients had involvement of both palms and

  11. Facing the challenge of stakeholders involvement: the Argentine nuclear regulatory case

    International Nuclear Information System (INIS)

    The Nuclear Regulatory Authority of Argentina (ARN) is an autonomous body reporting to the Presidency of Argentina, empowered to regulate and control the nuclear activity with regards to radiation and nuclear safety, physical protection and nuclear non-proliferation issues. Under the executive decree 1172/2003, which makes reference to the accessibility of public information to increase transparency of government actions and specially to promote public involvement, ARN has the legal obligation to inform of its activities in an accurate, comprehensive and understandable manner. The re-launching of the nuclear plan in 2006 and the repercussions this provoked on society highlighted the need to reinforce the legitimacy of the regulatory role and the promotion of confidence on its works to ensure the safety of the people. Therefore it was considered necessary to involve the society further in this programme by achieving greater public understanding and awareness of the nuclear regulatory activities. The more the public is conscious of the role of the regulator, conceiving it as a trustworthy and autonomous authority, the easier it is for the regulator to fulfil its obligations. As ARN has a strong commitment with society and considering that communication with the general public, as an external stakeholder, is a means to establishing and maintaining public trust and confidence, the implementation of a new communication programme became a key issue. In this scenario, ARN faced a challenge it was not prepared to handle and thus created a Division to deal with institutional communication and allow and ease the interaction with society. Within this Division, one of the methods chosen to achieve a better interaction with society was the use of a technological tool to attend possible inquiries, increasing and facilitating a greater involvement of the stakeholders. With this in mind a 'Mail-Info' was established because it allows a fast, accessible, easy and informal way of

  12. A rare case of paragonimiasis miyazakii with lung involvement diagnosed 7 years after infection: A case report and literature review.

    Science.gov (United States)

    Yatera, Kazuhiro; Hanaka, Minako; Hanaka, Tetsuya; Yamasaki, Kei; Nishida, Chinatsu; Kawanami, Toshinori; Kawanami, Yukiko; Ishimoto, Hiroshi; Kanazawa, Tamotsu; Mukae, Hiroshi

    2015-10-01

    We report a rare case of pulmonary paragonimiasis caused by Paragonimus miyazakii that showed pulmonary manifestations and a long-term clinical course after infection. A 45-year-old Japanese male developed cough and dyspnea in 2004 and was diagnosed with eosinophilic pneumonia. He had been treated with low-dose oral corticosteroid for 7 years. He recalled that he had consumed a large amount of raw freshwater crab (Geothelphusa dehaani) several weeks before he had been admitted for the first time, and that had been the only occasion when he had eaten this meat. The patient was referred to our hospital due to persistent hemoptysis, and his chest computed tomography scan showed pulmonary nodules and cavities, and his serum total IgE level was elevated. Bronchoscopy was performed, and ova were detected in the bronchoalveolar lavage fluid. The morphological examination of the ova and immunoserological examination yielded typical findings of P. miyazakii. Treatment with praziquantel improved his chest radiographic findings and a decrease of serum total IgE, as well as the values of immunoserological examination for P. miyazakii. The clinical course of this patient indicated that he had been infected with P. miyazakii for 7 years at least, which is unusual for paragonimiasis miyazakii. PMID:25771073

  13. Stakeholder Involvement in Tourism Destination Development: A Case of Dunga Beach and Wetland, Kisumu County, Kenya

    Directory of Open Access Journals (Sweden)

    Joshua Otieno Wanga

    2014-09-01

    In Kenya, Tourism is the second largest source of foreign exchange revenue following agriculture; it however, faces numerous challenges sustainability due the complex nature of tourism destinations. Tourism destinations are complex and dynamic systems that involve various stakeholders each with different understanding of same tourism system. These different perceptions can be tapped to develop a common tourism model that helps achieve the overall sustainable tourism development objective of a given destination. This paper describes participatory systems approach to develop a shared understanding amongst stakeholders of the tourism system in Dunga Beach and Wetland, in Kisumu County, Kenya. The process includes the development of a systems model that represents a holistic understanding of the interconnectedness and relationships between the various components that impact on sustainable development of tourism in Dunga. The model is intended for use as a framework for enhancing ecotourism experiences by stakeholders who are ecotourism experience providers in Dunga for the satisfaction of tourists in Dunga beach and wetland.

  14. Emerging Societal Involvement in City Management : the case of Cape Town

    Directory of Open Access Journals (Sweden)

    Neil Dewar

    1999-02-01

    Full Text Available Since the advent of full participatory democracy in South Africa in April 1994, a fundamental revision of the norms, values and practices of urban management has occurred. A central feature of this is expressed commitment to greater transparency and public participation in decision-making and project execution. Manegerial practice has moved from being essentially technocratic and control-oriented to more pluralistic and development-oriented. The previously disenfranchised and largely impoverished sectors of the community have moved from exclusion and confrontation toward greater involvement and empowerment. This has not been without problems however. The current status of community participation in Cape Town is reviewed and explored against a theoretical model. The conclusion drawn is that, political impediments notwithstanding, a considerable energy and momentum has been generated at local level in civil society towards the goal of improvement in social and living environments in the city.

  15. STUDY OF INJURY PATTERN IN HUMAN BEINGS IN ROAD TRAFFIC ACCIDENTS INVOLVING TWO WHEELERS

    Directory of Open Access Journals (Sweden)

    Seethalakshmi

    2015-09-01

    Full Text Available India experienced very rapid population growth from 48 million to 1.2 billion in a span of decades. In India rapid urbanization, industrialization, population explosion and migration of people in past two decades r esults in enormous growth in the field of road transportation. This resulted in increasing amount of the road traffic leading to increased risk for occurrence of road traffic accidents. In India road traffic injuries will be third leading cause of death by 2020 with the increase in the use of two wheelers and congestion and environmental pollution this mortality rate will continue to rise. Considering the preciousness of human lives, this study has been undertaken to analyse the pattern of injuries in Road Traffic Accidents Involving Two Wheelers to create awareness among the law enforcing authorities, transport authorities and public regarding two wheeler fatalities. A sincere attempt has been made in this study to analyse the distribution of the pattern of injuries sustained by two wheeler travellers, so that appropriate interventional strategies can be evolved at various levels and by different agencies. 147 Two wheeler Accident victims were randomly selected from 1063 road traffic accident cases brought t o the Institute of Forensic Medicine, Madras Medical College Chennai - 3 for routine medico legal examination. Preliminary data were collected from the medico legal documents such as history of the case, Inquest form, First Information Report, Accident Regis ter, Death Report, Clinical data submitted by the investigating officer at the time of medico legal examination. During autopsy, on external exami nation, nature of injury, size, number were measured in all cases. Internal organ injuries were recorded. Caus e of death was arrived at based on the findings made out during autopsy. Totally 147 motorcyclist victims were included in this study in which demographic factors such as age, sex, time of accident, manner of collision

  16. A case of swyer syndrome associated with advanced gonadal dysgerminoma involving long survival.

    Science.gov (United States)

    Da Silva Rios, Salete; Monteiro, Isabella Christina Mazzaro; Braz Dos Santos, Larissa Gonçalves; Caldas, Natasha Garcia; Chen, Ana Carolina Rios; Chen, Juliana Rios; Silva, Helena Spindola Camargo

    2015-01-01

    Swyer syndrome is caused by abnormal sex differentiation during the embryonic period, resulting in incomplete intrauterine masculinization and undifferentiated gonads. The current case report describes a patient with Swyer syndrome associated with stage 3 gonadal dysgerminoma who has survived for 23 years. At age 18, this patient sought assistance for primary amenorrhea from the Gynecological Services Department of the University of Brasília Hospital. A physical examination revealed that the patient was at Tanner stage 4 with respect to axillary hair, breasts, and pubic hair; she presented with a eutrophic vagina and a small cervix. She was treated with a combination of estrogens and progestogens to induce cycling. Approximately 4 years later, a complex tumor was found and resected; a histopathological analysis revealed that this tumor was a right adnexal dysgerminoma with peritoneal affection. The patient was also subjected to chemotherapy. Her follow-up has continued to the present time, with no signs of tumor recurrence. In conclusion, this report describes an extremely rare case in which Swyer syndrome was associated with ovarian dysgerminoma; relative to similar patients, the described patient has survived for an unusually prolonged time. PMID:25960730

  17. A Case of Swyer Syndrome Associated with Advanced Gonadal Dysgerminoma Involving Long Survival

    Directory of Open Access Journals (Sweden)

    Salete Da Silva Rios

    2015-03-01

    Full Text Available Swyer syndrome is caused by abnormal sex differentiation during the embryonic period, resulting in incomplete intrauterine masculinization and undifferentiated gonads. The current case report describes a patient with Swyer syndrome associated with stage 3 gonadal dysgerminoma who has survived for 23 years. At age 18, this patient sought assistance for primary amenorrhea from the Gynecological Services Department of the University of Brasília Hospital. A physical examination revealed that the patient was at Tanner stage 4 with respect to axillary hair, breasts, and pubic hair; she presented with a eutrophic vagina and a small cervix. She was treated with a combination of estrogens and progestogens to induce cycling. Approximately 4 years later, a complex tumor was found and resected; a histopathological analysis revealed that this tumor was a right adnexal dysgerminoma with peritoneal affection. The patient was also subjected to chemotherapy. Her follow-up has continued to the present time, with no signs of tumor recurrence. In conclusion, this report describes an extremely rare case in which Swyer syndrome was associated with ovarian dysgerminoma; relative to similar patients, the described patient has survived for an unusually prolonged time.

  18. Pontine extension of a tentorial schwannoma without cranial nerve involvement: a case report

    Directory of Open Access Journals (Sweden)

    D'Urso Pietro

    2011-12-01

    Full Text Available Abstract Introduction Intracranial schwannomas unrelated to the cranial nerves are uncommon. We report a new case of tentorial schwannoma unrelated to the cranial nerves, with extension into the pons. A literature review with discussion of the most relevant pathogenetic aspects is also performed. Case presentation A 42-year-old Caucasian man was admitted with right-sided paresthesias and weakness of his upper and lower extremities. The neurological examination revealed right hemiparesis and hemi-hypoesthesia. A brain magnetic resonance imaging scan revealed a cerebellopontine lesion, arising from the left free edge of the tentorium, and extending into his pons. A piecemeal removal was performed through a retrosigmoid approach. The lesion was not found to be associated with any cranial nerves. The histological examination revealed a schwannoma Antoni type A. His postoperative course was uneventful. At one year follow-up, the patient was neurologically intact and the magnetic resonance imaging of his brain performed at that time showed complete removal without signs of recurrence. Conclusion Tentorial schwannomas are rare clinical entities. Knowledge of their clinical, radiological and anatomical characteristics is very important for the correct diagnosis and management.

  19. Integrated dementia care in The Netherlands: a multiple case study of case management programmes.

    Science.gov (United States)

    Minkman, Mirella M N; Ligthart, Suzanne A; Huijsman, Robbert

    2009-09-01

    The number of dementia patients is growing, and they require a variety of services, making integrated care essential for the ability to continue living in the community. Many healthcare systems in developed countries are exploring new approaches for delivering health and social care. The purpose of this study was to describe and analyse a new approach in extensive case management programmes concerned with long-term dementia care in The Netherlands. The focus is on the characteristics, and success and failure factors of these programmes.A multiple case study was conducted in eight regional dementia care provider networks in The Netherlands. Based on a literature study, a questionnaire was developed for the responsible managers and case managers of the eight case management programmes. During 16 semistructured face-to-face interviews with both respondent groups, a deeper insight into the dementia care programmes was provided. Project documentation for all the cases was studied. The eight programmes were developed independently to improve the quality and continuity of long-term dementia care. The programmes show overlap in terms of their vision, tasks of case managers, case management process and the participating partners in the local dementia care networks. Differences concern the targeted dementia patient groups as well as the background of the case managers and their position in the local dementia care provider network. Factors for success concern the expert knowledge of case managers, investment in a strong provider network and coherent conditions for effective inter-organizational cooperation to deliver integrated care. When explored, caregiver and patient satisfaction was high. Further research into the effects on client outcomes, service use and costs is recommended in order to further analyse the impact of this approach in long-term care. To facilitate implementation, with a focus on joint responsibilities of the involved care providers, policy

  20. Dental trauma involving root fracture and periodontal ligament injury: a 10-year retrospective study

    Directory of Open Access Journals (Sweden)

    Sônia Regina Panzarini

    2008-09-01

    Full Text Available The purpose of this retrospective study was to analyze the cases of traumatic dental injuries involving root fracture and/or periodontal ligament injury (except avulsion treated at the Discipline of Integrated Clinic, School of Dentistry of Araçatuba, São Paulo State University (UNESP, Brazil, from January 1992 to December 2002. Clinical and radiographic records from 161 patients with 287 traumatized teeth that had sustained root fracture and/or injuries to the periodontal ligament were examined. The results of this survey revealed that subluxation (25.09% was the most common type of periodontal ligament injury, followed by extrusive luxation (19.86%. There was a predominance of young male patients and most of them did not present systemic alterations. Among the etiologic factors, the most frequent causes were falls and bicycle accidents. Injuries on extraoral soft tissues were mostly laceration and abrasion, while gingival and lip mucosa lacerations prevailed on intraoral soft tissues injuries. Radiographically, the most common finding was an increase of the periodontal ligament space. The most commonly performed treatment was root canal therapy. Within the limits of this study, it can be concluded that traumatic dental injuries occur more frequently in young male individuals, due to falls and bicycle accidents. Subluxation was the most common type of periodontal ligament injury. Root canal therapy was the type of treatment most commonly planned and performed.

  1. Dental trauma involving root fracture and periodontal ligament injury: a 10-year retrospective study.

    Science.gov (United States)

    Panzarini, Sônia Regina; Pedrini, Denise; Poi, Wilson Roberto; Sonoda, Celso Koogi; Brandini, Daniela Atili; Monteiro de Castro, José Carlos

    2008-01-01

    The purpose of this retrospective study was to analyze the cases of traumatic dental injuries involving root fracture and/or periodontal ligament injury (except avulsion) treated at the Discipline of Integrated Clinic, School of Dentistry of Araçatuba, São Paulo State University (UNESP), Brazil, from January 1992 to December 2002. Clinical and radiographic records from 161 patients with 287 traumatized teeth that had sustained root fracture and/or injuries to the periodontal ligament were examined. The results of this survey revealed that subluxation (25.09%) was the most common type of periodontal ligament injury, followed by extrusive luxation (19.86%). There was a predominance of young male patients and most of them did not present systemic alterations. Among the etiologic factors, the most frequent causes were falls and bicycle accidents. Injuries on extraoral soft tissues were mostly laceration and abrasion, while gingival and lip mucosa lacerations prevailed on intraoral soft tissues injuries. Radiographically, the most common finding was an increase of the periodontal ligament space. The most commonly performed treatment was root canal therapy. Within the limits of this study, it can be concluded that traumatic dental injuries occur more frequently in young male individuals, due to falls and bicycle accidents. Subluxation was the most common type of periodontal ligament injury. Root canal therapy was the type of treatment most commonly planned and performed. PMID:18949308

  2. Case Study Report about Gender Impact Assessment

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Agustin, Lise Rolandsen

    2013-01-01

    The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish...... Ministry of Employment and the Danish Ministry of Transport, respectively) the aim is to assess the transformative potential of GIA as it is performed in Denmark....

  3. Gigantic Suprapubic Lymphedema: A Case Study.

    Science.gov (United States)

    Tanhaeivash, Roozbeh; Franiel, Tobias; Grimm, Marc-Oliver; Horstmann, Marcus

    2016-08-01

    We present the first case study of idiopathic gigantic suprapubic lymphedema and buried penis treated with puboscrotal reconstruction in a patient with initial extreme obesity after an extensive weight reduction (120 kg). Massive localized lymphedema of the suprapubic region should be differentiated from the scrotal type. Severe lymphedema could not resolve on its own and weight reduction does not seem to be helpful in such cases. PMID:27574599

  4. Case Study Research Methodology in Nursing Research.

    Science.gov (United States)

    Cope, Diane G

    2015-11-01

    Through data collection methods using a holistic approach that focuses on variables in a natural setting, qualitative research methods seek to understand participants' perceptions and interpretations. Common qualitative research methods include ethnography, phenomenology, grounded theory, and historic research. Another type of methodology that has a similar qualitative approach is case study research, which seeks to understand a phenomenon or case from multiple perspectives within a given real-world context.

  5. Gigantic Suprapubic Lymphedema: A Case Study

    Science.gov (United States)

    Tanhaeivash, Roozbeh; Franiel, Tobias; Grimm, Marc-Oliver

    2016-01-01

    We present the first case study of idiopathic gigantic suprapubic lymphedema and buried penis treated with puboscrotal reconstruction in a patient with initial extreme obesity after an extensive weight reduction (120 kg). Massive localized lymphedema of the suprapubic region should be differentiated from the scrotal type. Severe lymphedema could not resolve on its own and weight reduction does not seem to be helpful in such cases. PMID:27574599

  6. Blood concentrations of clobazam and norclobazam in a lethal case involving clobazam, meprobamate and clorazepate.

    Science.gov (United States)

    Pok, Phak-Rop Pos; Mauras, Michel; De Saint Léger, Marie-Noëlle; Kuhlmann, Erika; Charpenel-Durat, Catherine; Navarette, Claudie; Duval, Marie-Laure; De Meo, Pierre

    2010-11-01

    Clobazam is a benzodiazepine with anti-anxiety and anticonvulsant properties marketed in several countries. Norclobazam, a metabolite of clobazam, has similar pharmacological activity but weaker sedative and tranquilizing effect. The two drugs were detected by GC-MS and determined by HPLC-DAD in the samples from a postmortem case. The femoral blood concentrations of clobazam and norclobazam were 0.72 and 36 μg/mL, respectively. The concentration of the active norclobazam was very high. The sum of both clobazam and norclobazam blood concentration (36.72 μg/mL) was clearly toxic, but was not necessarily fatal. Other associated drugs concentrations were within their therapeutic ranges. Interactions due to drug association were discussed. PMID:20870445

  7. Classroom Climate, Parental Educational Involvement, and Student School Functioning in Early Adolescence: A Longitudinal Study

    Science.gov (United States)

    Kaplan Toren, Nurit; Seginer, Rachel

    2015-01-01

    In this 2-year longitudinal study, we examine the effects of perceived classroom climate and two aspects of parental educational involvement (home-based and school-based) on junior high school students' self-evaluation and academic achievement. Our main hypothesis was that perceived parental educational involvement mediates students' perceived…

  8. Elderly patients' and GPs' views on different methods for patient involvement: an international qualitative interview study.

    NARCIS (Netherlands)

    Geest, T.A.; Wetzels, R.V.; Raposo, V.; Ferreira, P.L.; Baker, R.; Wensing, M.J.P.; Olesen, F.

    2005-01-01

    BACKGROUND: Elderly patients' interaction with the GP may be improved through patient involvement techniques, and there is a variety of such techniques which improve patients' involvement in their own care, although little is known about their acceptability. OBJECTIVES: The aim of this study was to

  9. A Prospective Longitudinal Study of Children's Theory of Mind and Adolescent Involvement in Bullying

    Science.gov (United States)

    Shakoor, Sania; Jaffee, Sara R.; Bowes, Lucy; Ouellet-Morin, Isabelle; Andreou, Penelope; Happe, Francesca; Moffitt, Terrie E.; Arseneault, Louise

    2012-01-01

    Background: Theory of mind (ToM) allows the understanding and prediction of other people's behaviours based on their mental states (e.g. beliefs). It is important for healthy social relationships and thus may contribute towards children's involvement in bullying. The present study investigated whether children involved in bullying during early…

  10. School, Neighborhood, and Family Factors Are Associated with Children's Bullying Involvement: A Nationally Representative Longitudinal Study

    Science.gov (United States)

    Bowes, Lucy; Arseneault, Louise; Maughan, Barbara; Taylor, Alan; Caspi, Ashalom; Moffitt, Terrie E.

    2009-01-01

    School size and problems with neighbors is associated with a greater risk of being a bullying victim while family factors such as maltreatment and domestic violence are associated with involvement in bullying. The findings are based on the Environmental Risk Longitudinal Twin Study that involves 2,232 children.

  11. The Future of the Food System: Cases Involving the Private Sector in South Africa

    Directory of Open Access Journals (Sweden)

    Laura M. Pereira

    2013-03-01

    Full Text Available The food system is facing unprecedented pressure from environmental change exacerbated by the expansion of agri-food corporations that are consolidating their power in the global food chain. Although Africa missed the Green Revolution and the wave of supermarket expansion that hit the West and then spread to Asia and Latin America, this is unlikely to continue. With a large proportion of sub-Saharan African countries’ GDP still heavily reliant on agriculture, global trends in agri-food business are having an increasing impact on African countries. South Africa, a leader in agribusiness on the continent, has a well-established agri-food sector that is facing increasing pressure from various social and environmental sources. This paper uses interview data with corporate executives from South African food businesses to explore how they are adapting to the dual pressures of environmental change and globalisation. It shows that companies now have to adapt to macro-trends both within and outside the formal food sector and how this in turn has repercussions for building sustainable farming systems—both small and large-scale. It concludes with the recognition that building a sustainable food system is a complex process involving a diversity of actors, however changes are already being seen. Businesses have strategically recognised the need to align the economic bottom line with social and environmental factors, but real sustainability will only happen when all stakeholders are included in food governance.

  12. INVOLVEMENT OF SYNAPTIC GENES IN THE PATHOGENESIS OF AUTISM SPECTRUM DISORDERS: THE CASE OF SYNAPSINS

    Directory of Open Access Journals (Sweden)

    Silvia eGiovedi

    2014-09-01

    Full Text Available Autism spectrum disorders (ASDs are heterogeneous neurodevelopmental disorders characterized by deficits in social interaction and social communication, restricted interests and repetitive behaviors. Many synaptic protein genes are linked to the pathogenesis of ASDs, making them prototypical synaptopathies. An array of mutations in the synapsin (Syn genes in humans have been recently associated with ASD and epilepsy, diseases that display a frequent comorbidity. Synapsins are presynaptic proteins regulating synaptic vesicle traffic, neurotransmitter release and short-term synaptic plasticity. In doing so, Syn isoforms control the tone of activity of neural circuits and the balance between excitation and inhibition. As ASD pathogenesis is believed to result from dysfunctions in the balance between excitatory and inhibitory transmissions in neocortical areas, Syns are novel ASD candidate genes. Accordingly, deletion of single Syn genes in mice, in addition to epilepsy, causes core symptoms of ASD by affecting social behavior, social communication and repetitive behaviors. Thus, Syn knockout mice represent a good experimental model to define synaptic alterations involved in the pathogenesis of ASD and epilepsy.

  13. Clean Cities Case Study: Barwood Cab Fleet Study Summary

    International Nuclear Information System (INIS)

    Barwood Cab Fleet Study Summary is the second in a new series called''Alternative Fuel Information Case Studies,'' designed to present real-world experiences with alternative fuels to fleet managers and other industry stakeholders

  14. Social Studies Project Evaluation: Case Study and Recommendations.

    Science.gov (United States)

    Napier, John

    1982-01-01

    Describes the development and application of a model for social studies program evaluations. A case study showing how the model's three-step process was used to evaluate the Improving Citizenship Education Project in Fulton County, Georgia is included. (AM)

  15. Connecting Reading and Writing: A Case Study

    Science.gov (United States)

    Li, Zhanfang

    2015-01-01

    Connecting reading and writing, proposed by many scholars, is realized in this case study. The 30 participants in this study are the English majors of the third year in one School of Foreign Languages in Beijing. They are encouraged to write journals every week, based on the source text materials in their Intensive Reading class, with the final…

  16. Collaborative Assessment: Middle School Case Study

    Science.gov (United States)

    Parkison, Paul T.

    2014-01-01

    Utilizing a participant observer research model, a case study of the efficacy of a collaborative assessment methodology within a middle school social studies class was conducted. A review of existing research revealed that students' perceptions of assessment, evaluation, and accountability influence their intrinsic motivation to learn. A…

  17. A Multiple Case Study of Innovation

    Science.gov (United States)

    Zheng, Wei; Khoury, Anne E.

    2008-01-01

    This study aims to explore how leadership and contextual factors influence innovation in R&D teams in national laboratories, using the approach of multiple case studies. This paper provides some preliminary findings from two highly innovative teams residing in two national laboratories in the US. The preliminary results suggested several common…

  18. Measuring marketing performance - A case study

    OpenAIRE

    Laakso, Vesa-Pekka

    2011-01-01

    PURPOSE OF THE STUDY The purpose of this study is to develop a marketing dashboard for a Finnish company that operates in the financial industry. The identification of suitable metrics for assessing marketing performance is considered central. This study proposes a new construct (a dashboard) that aims to providing management relevant information on marketing performance from decision-making perspective. METHODOLOGY AND DATA The methodology is a constructive case study. In the...

  19. University Response to Crisis Events Involving International Populations: The Case of Seven Directors of International Offices

    Science.gov (United States)

    Andrews, James P.

    2012-01-01

    This qualitative research study focuses on crisis events affecting university international populations. It explores how seven directors of university international offices at seven different geographical locations in Texas respond to those events. The study findings shed light on the current state of crisis preparedness in higher education from…

  20. Trends in Dissertations Involving Technology-Assisted Mathematics Instruction: The Case of Turkey

    Science.gov (United States)

    Tatar, Enver; Akkaya, Adnan; Kagizmanli, Türkan Berrin

    2014-01-01

    The purpose of this study is to examine thesis studies on technology-supported mathematics education in Turkey in terms of the keywords, mathematical areas, technologies and methodology used and results obtained. Data were obtained from 105 graduate theses. At the end of the analysis of the data, it was determined that most used keywords were from…

  1. Mining Product Data Models: A Case Study

    Directory of Open Access Journals (Sweden)

    Cristina-Claudia DOLEAN

    2014-01-01

    Full Text Available This paper presents two case studies used to prove the validity of some data-flow mining algorithms. We proposed the data-flow mining algorithms because most part of mining algorithms focuses on the control-flow perspective. First case study uses event logs generated by an ERP system (Navision after we set several trackers on the data elements needed in the process analyzed; while the second case study uses the event logs generated by YAWL system. We offered a general solution of data-flow model extraction from different data sources. In order to apply the data-flow mining algorithms the event logs must comply a certain format (using InputOutput extension. But to respect this format, a set of conversion tools is needed. We depicted the conversion tools used and how we got the data-flow models. Moreover, the data-flow model is compared to the control-flow model.

  2. Integrating Ethics into Case Study Assignments

    Directory of Open Access Journals (Sweden)

    Pamela A. Marshall

    2014-08-01

    Full Text Available I teach an upper-level writing course, Genes, Race, Gender, and Society, designed for Life Science majors, in which I utilize a case study to expose students to ethical ways of thinking.  Students first work through the topical case study and then are challenged to rethink their responses through the lenses of ethics, taking into account different ethical frameworks.  Students then develop their own case study, integrating ethical components.  I want to expose my students to this way of thinking because I see technology being driven by the Jurassic Park phenomenon, "Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should." and want future physicians grounded in a sense of how their actions relate to the greater good.

  3. Shuttle Case Study Collection Website Development

    Science.gov (United States)

    Ransom, Khadijah S.; Johnson, Grace K.

    2012-01-01

    As a continuation from summer 2012, the Shuttle Case Study Collection has been developed using lessons learned documented by NASA engineers, analysts, and contractors. Decades of information related to processing and launching the Space Shuttle is gathered into a single database to provide educators with an alternative means to teach real-world engineering processes. The goal is to provide additional engineering materials that enhance critical thinking, decision making, and problem solving skills. During this second phase of the project, the Shuttle Case Study Collection website was developed. Extensive HTML coding to link downloadable documents, videos, and images was required, as was training to learn NASA's Content Management System (CMS) for website design. As the final stage of the collection development, the website is designed to allow for distribution of information to the public as well as for case study report submissions from other educators online.

  4. Estudo da utilização de materiais de referência nas análises de água por laboratórios envolvidos no sistema de acreditação Case study on the usage of reference materials in water analysis by laboratories involved in the accreditation system

    Directory of Open Access Journals (Sweden)

    Suzana Saboia de Moura

    2009-01-01

    Full Text Available O presente estudo propõe-se discutir o uso de materiais de referência (MR pelos laboratórios de ensaios de águas, sob o ponto de vista da aquisição dos materiais conforme o item "Aquisição de serviços e suprimentos" (4.6 da norma ABNT NBR ISO/IEC 17025. O papel dos MR nas análises químicas é fornecer referências metrológicas visando assegurar a rastreabilidade das medições. A rastreabilidade é um aspecto essencial da garantia da qualidade para se obter aceitação de dados analíticos nos mercados nacional e internacional. Neste estudo de caso, de caráter exploratório e qualitativo, uma pesquisa foi realizada junto a todos os laboratórios de ensaios prestadores de serviços analíticos para a Agência Nacional de Águas (ANA e envolvidos no sistema de acreditação pela Coordenação Geral de Acreditação do Inmetro (Cgcre/Inmetro, utilizando-se questionário estruturado e com 50% de retorno. Os resultados mostraram que são muito poucos os certificados de MR com reconhecimento de terceira parte, ou seja, por organismos de acreditação, segundo normas consagradas que tratam efetivamente da rastreabilidade metrológica. Propõe-se, finalmente, uma política para garantir, sempre que possível, a rastreabilidade dos resultados de ensaios dos laboratórios, na ausência de MR certificados.This paper aims at discussing the use of reference materials (RM by water testing laboratories, on the context of RM purchase, based on the requirements of the standard ABNT NBR ISO/IEC 17025, section "Purchasing services and supplies" (4.6. The role of RM in chemical analysis is to provide metrological reference to assure measurement traceability. This is an essential aspect of quality assurance in order to have analytical results accepted in the international market. In this case study, based on the methodological exploratory and qualitative approach, a questionnaire was sent to testing laboratories which provide analytical services to the

  5. Primary testicular lymphoma with cardiac involvement in an immunocompetent patient: case report and a concise review of literature

    Directory of Open Access Journals (Sweden)

    Richard Steingart

    2012-06-01

    Full Text Available Primary testicular lymphoma (PTL is a rare testicular tumor representing less than 9% of all testicular cancers. PTL usually tends to spread to or relapse at nodal structures or extra-nodal sites such as contralateral testes, central nervous system, skin, lung, pleura, waldeyer’s ring and soft tissues. We present a case of PTL with huge left atrial mass, an extremely unusual site of involvement. Early disease usually carries a good prognosis, whereas advanced stage carries an extremely poor prognosis. Herein, we report the complete remission to date in a patient with advanced stage PTL with huge left atrial mass, treated with systemic rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone and intrathecal methotrexate. A brief review of literature focusing on various aspects of management of primary testicular lymphoma and lymphomatous involvement of heart is also discussed.

  6. Solitary axillary lymph node metastasis without breast involvement from ovarian Cancer: Case report and brief literature review

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Ji In; Kim, Soo Jin; Park, Sung Hee; Kim, Hee Sung [Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul (Korea, Republic of)

    2014-11-15

    Axillary lymph node metastasis without breast involvement from ovarian cancer is rare. We report a case of a 68-year-old woman proven as ovarian serous papillary carcinoma and metastatic papillary carcinoma of the omentum on surgical diagnostic laparoscopy. In addition, a hypermetabolic lymph node was detected in left axilla and was considered a reactive benign lesion. Mammography and ultrasonography showed no focal lesion in both breasts, but ultrasonography-guided core needle biopsy for the lymph node revealed metastatic serous papillary carcinoma from ovarian origin. Even with a low incidence of axillary lymph node metastasis without breast involvement from ovarian cancer and only marginally elevated standardized uptake value in positron emission tomography, the possibility of metastasis at axillary lymph node in patients with known primary ovarian cancer must be considered.

  7. Fatal Intoxication Involving 3-MeO-PCP: A Case Report and Validated Method.

    Science.gov (United States)

    Bakota, Erica; Arndt, Crystal; Romoser, Amelia A; Wilson, Stephen K

    2016-09-01

    We present in this case report a validated method for accurate quantitative analysis of 3-methoxy phencyclidine (3-MeO-PCP) to determine postmortem blood concentrations of this PCP analog. A 29-year-old male with a history of illicit drug use was found unresponsive in his bed with a bag of white powder next to him. Resuscitation efforts were unsuccessful and the individual was pronounced dead 9 minutes after arrival to the hospital. Initial ELISA screening suggested the presence of PCP in the decedent's blood. However, confirmatory testing revealed no detectable PCP. Instead, a large peak corresponding to a m/z 274.218 species with retention time similar to PCP was present on a LC-TOF-MS drug screen, suggesting a possible PCP analog. This mass corresponds specifically to a methoxy-PCP analog, several of which are available for purchase online. Standards for 3-MeO-PCP and 4-MeO-PCP were obtained and injected on the same instrument. Although the 3- and 4-MeO-PCP analogs have identical masses and retention times, they are still distinguishable through their mass spectra. The peak from the decedent's sample matched both the mass spectrum and the retention time of 3-MeO-PCP. A quantitative LC-MS-MS method was subsequently developed and validated for casework. Analysis using this method revealed a concentration of 139 ± 41 µg/L 3-MeO-PCP in the decedent's blood. Diphenhydramine (4.1 ± 0.7 mg/L), marijuana metabolite (presumptive positive, confirmation not performed) and a small amount of amphetamine (<0.10 mg/L) were also found in the decedent's blood. The cause of death was determined to be combined 3-MeO-PCP, diphenhydramine and amphetamine toxicity. The manner of death was certified as an accident. PMID:27339479

  8. SYNONYMS IN ACTION: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Rebecca Clift

    2003-05-01

    Full Text Available This paper discusses what the methods of conversation analysis (CA might have to offer the study of linguistic synonymy. It takes as a case study two items commonly held to be synonyms -'actually' and 'in fact'- and shows considerable differences between the two in their interactional implementation: they are implicated in the prosecution of differing courses of action. Such cases argue that it is analytically more profitable to consider what a lexical item does in the context of talk than what it means.

  9. Repurposing legacy data innovative case studies

    CERN Document Server

    Berman, Jules J

    2015-01-01

    Repurposing Legacy Data: Innovative Case Studies takes a look at how data scientists have re-purposed legacy data, whether their own, or legacy data that has been donated to the public domain. Most of the data stored worldwide is legacy data-data created some time in the past, for a particular purpose, and left in obsolete formats. As with keepsakes in an attic, we retain this information thinking it may have value in the future, though we have no current use for it. The case studies in this book, from such diverse fields as cosmology, quantum physics, high-energy physics, microbiology,

  10. Wind farm repowering: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Selva, L. [Renewable Energy Eng. (Spain); Canas, M.; Gomez, E.; Pujante, A [Renewable Energy Research Inst., Dept. of Electrical, Electronic and Control Eng. (Spain)

    2007-11-15

    Wind farm repowering involves the replacement of smaller and middle sized wind turbines, with state-of-the-art multi-megawatt turbines. In this paper, a detailed study of the repowering of a wind farm is presented, by computing the generated active power from existing wind turbines and the new ones. The active power generated with the wind turbines are totalized to obtain the yearly generated energy and analyzed, thus economic studies take the repowering cost into account too. (au)

  11.  Transient Osteoporosis of the Hip/Bone Marrow Edema Syndrome with Soft Tissue Involvement: A Case Report

    Directory of Open Access Journals (Sweden)

    Mohamad A. Al-Tanni

    2011-09-01

    Full Text Available  Transient osteoporosis of the hip (TOH is a rare condition mainly affecting pregnant women in their third trimester and middle aged men. We report a case of TOH/Bone marrow edema syndrome in pregnancy with involvement of the surrounding soft tissues on magnetic resonance image, which has not been previously reported. The presence of such edema in the soft tissues may help to differentiate this condition from early avascular necrosis of the hip, and may also provide an insight into the pathogenesis of the condition. The reported patient was treated conservatively and fully recovered.

  12. Non-infringement Suit Involving Dispute over Trademark Infringement--Comments on the Case of Peter Rabbit Trademarks infringement

    Institute of Scientific and Technical Information of China (English)

    Jiang Ying

    2005-01-01

    @@ The Case in Brief The plaintiff: the China Social Sciences Press (CSSP) The defendant: Frederick Warne & Co., Ltd. (FW) Cause of action: Dispute involving establishment of non-infringement of the exclusive right to use registered trademarks In April,2003, the CSSP published a series of books entitled the Peter Rabbit Series, which comprises four separate volumes of books: the Tale of Peter Rabbit,the Tale of Mrs Tittlemouse, the Tale of Tom Kitten, and the Tale of Pigling Bland.This series, published in Chinese and English, had collected 19 fairy tales written by the woman English writer Beatrix Potter, who passed away over 50 years ago.

  13. Corporate Social Responsibility : A Case Study

    OpenAIRE

    Björkqvist, Kira

    2012-01-01

    The importance of taking responsibility for the common environmental and social welfare has become of essence in the business world of the 21st century. This thesis provides the reader with knowledge on corporate social responsibility (CSR) and shows the reader a comparative study on how CSR is reported on in three case study companies chosen for this thesis. This thesis is a descriptive study that uses the research method of content analysis to determine the commonalities and differences...

  14. Pseudoaxonal Guillain-Barré syndrome: severe demyelination mimicking axonopathy. A case with pupillary involvement.

    OpenAIRE

    Fuller, G N; Jacobs, J. M.; Lewis, P D; Lane, R J

    1992-01-01

    A patient with fulminant Guillain-Barré syndrome developed pupillary denervation, loss of all brain stem reflexes and a complete flaccid quadriparesis. Pathological studies confirmed this was due to a primarily demyelinating process and not an axonal form of Guillain-Barré syndrome.

  15. Assessment of human decision reliability - a case study

    International Nuclear Information System (INIS)

    In his discussion of this case study, the author indicates that human beings are not merely machines who use rules. Thus, more focus needs to be put on studying decision making situations and their contexts. Decision theory (both normative and descriptive) and contextual psychological approaches may offer tools to cope with operator decision making. Further an ideal decision space needs to be defined for operators. The case study specifically addressed a loss of feedwater scenario and the various operator decisions that were involved in that scenario. It was concluded from this particular study that there are significant differences in the crew decision behaviours that are not explained by process variables. Through use of evidence from simulator tests with expert judgement, an approach to estimate probabilities has been developed. The modelling approach presented in this discussion is an extension of current HRA paradigms, but a natural one since all human beings make decisions

  16. Capturing Cultural Glossaries: Case-study I *

    Directory of Open Access Journals (Sweden)

    Matete Madiba

    2011-10-01

    Full Text Available

    Abstract: This article is a presentation of a brief cultural glossary of Northern Sotho cooking terms. The glossary is mainly composed of names for utensils and ingredients, and action words for the processes involved in the preparation of cultural dishes. It also contains names of dishes tied to some idiomatic expressions in a way eliciting cultural experiences that can lead to an under-standing of indigenous knowledge systems. The article seeks to explore ways of capturing cultural glossaries to feed into the national dictionary corpora by using a case-study approach to investigate the processes that led to the generation of this specific school-based project. A number of issues that surfaced in this project, can possibly serve as models for the collection of authentic glossaries that can support dictionary making in African languages.

    Keywords: CULTURAL GLOSSARY, INDIGENOUS KNOWLEDGE SYSTEMS, CULTURAL TERMINOLOGY, CORPUS, AUTHENTIC GLOSSARY, CONTEXTUALISATION, MARGIN-ALIZED LANGUAGES, OUTCOMES-BASED EDUCATION, PERFORMANCE INDICATOR, ASSESSMENT CRITERIA, RANGE STATEMENT, TRADITIONAL DISHES, LANGUAGE VAL-ORISATION, SIMULTANEOUS FEEDBACK, COMMUNICATIVE APPROACH, STRUCTURAL APPROACH, METONYMY

    Opsomming: Die totstandbrenging van kulturele woordversamelings: Ge-vallestudie I. Hierdie artikel is 'n aanbieding van 'n kort kulturele woordversameling van Noord-Sothokookterme. Die woordversameling bestaan hoofsaaklik uit die name van gereedskap en bestanddele, en handelingswoorde vir die prosesse betrokke by die voorbereiding van kulturele geregte. Dit bevat ook name van geregte wat verbind is met sekere idiomatiese uitdrukkings wat op 'n manier kulturele ervarings oproep wat kan lei tot die verstaan van inheemse kennisstelsels. Die artikel probeer om maniere te ondersoek waarop kulturele woordversamelings in die nasionale woordeboekkorpusse ingevoer kan word deur 'n gevallestudiebenadering te volg om die prosesse te ondersoek wat tot die

  17. Advertising expenditure as a determinant of a brand's share of the market (A case with low and high involvement products)

    OpenAIRE

    Lalanananda, Weerasinghe Gunawardana Thusitha Sanjeewa

    2007-01-01

    This study attempted to determine the impact of brand’s advertising expenditure on its share of the market and its variation, if any, across different product categories (i.e., lowinvolvement vs. high- involvement products). In this endeavor, the study challenged common belief amongst marketers, that the normal and stable relationship for an advertised brand is a parity of share of voice and share of market. The findings of the study revealed a positive correlation between a br...

  18. Microbial study of meningitis and encephalitis cases.

    Science.gov (United States)

    Selim, Heba S; El-Barrawy, Mohamed A; Rakha, Magda E; Yingst, Samuel L; Baskharoun, Magda F

    2007-01-01

    Meningitis and/or encephalitis can pose a serious public health problem especially during outbreaks. A rapid and accurate diagnosis is important for effective earlier treatment. This study aimed to identify the possible microbial causes of meningitis and/or encephalitis cases. CSF and serum samples were collected from 322 patients who had signs and symptoms suggestive of meningitis and/or encephalitis. Out of 250 cases with confirmed clinical diagnosis, 83 (33.2%) were definitely diagnosed as bacterial meningitis and/or encephalitis cases (by using CSF culture, biochemical tests, latex agglutination test, and CSF stain), 17 (6.8%) were definitely diagnosed as having viral causes ( by viral isolation on tissue culture, PCR and ELISA), and one (0.4%) was diagnosed as fungal meningitis case (by India ink stain, culture, and biochemical tests). Also, there was one encephalitis case with positive serum ELISA IgM antibodies against Sandfly scilian virus. N. meningitidis, S. pneumonia and M. tuberculosis were the most frequently detected bacterial agents, while Enteroviruses, herpes simplex viruses and varicella zoster viruses were the most common viral agents encountered. Further studies are needed to assess the role of different microbial agents in CNS infections and their effective methods of diagnosis.

  19. Involving consumers in product design through collaboration: the case of online role-playing games.

    Science.gov (United States)

    Yeh, Shu-Yu

    2010-12-01

    The release of software attributes to users by software designers for the creation of user-designed forms is regarded as a producer-consumer collaboration, leading consumers to expend significant effort on a specific product. This article identifies such software/product attributes within online role-playing games and then explores how consumers' prior experience affects the evaluation of such attributes. In this article, product attributes comprise customized, content, and interactive externality-sensitive and complementary externality-sensitive attributes, with the value of each attribute being greater for experts than for novices. In Study 1, data were collected and analyzed for the purpose of identifying such features in online role-playing games. The results can also be generalized to convergent products, such as TV games that have been redesigned as online games or mobile games found in Study 2. For the introduction of a convergent product to be successful, our research suggests that the potential market-segment focus should be on knowledgeable consumers who accept such products more readily.

  20. The JMB Applied Chemistry Syllabus--the Place of Case Studies and Industrial Processes

    Science.gov (United States)

    Hallas, G.; Hughes, W. J.

    1974-01-01

    Describes two novel topics in the JMB Applied Chemistry Core Syllabus. These are the social and economic aspects of chemical technology, involving the use of six case studies, and industrial processes. (Author/GS)

  1. Studying Tourism Indicators In Iran (Case Study: Khoramabad City

    Directory of Open Access Journals (Sweden)

    Mahdi Garavand

    2014-12-01

    Full Text Available Now tourism industry is one of the greatest World Industries from point of view development and with attention to be use financial sources and involved persons with that. This industry, has third rank in financial and commercial classifications and including more than 7 percent of whole world exports, also it influence gross national product in all countries; so that increase rate of gross national product 2billion $ in all world nations. Tourism industry important to stress tow important ways: first, the dynamic familiarity with other cultures, nations, races, tribes, dialects and …; second, it provides sources of income and foreign exchanges from an economic point of view. The different world countries fallowed attraction of tourists because of that they have various facilities and various attractions.Iran is ranked as one of the 10 top attractive countries in the world but Iran was place 114th ranking of the countries in terms of attracting tourists (World Economic Forum, 2011, tourism receipts is ranked as 77th, and the number of international tourists arrivals ranked as place 70th (UNWTO, 2009.So, the aim of this research is, studying main indicators in tourism location in order to improving their qualify. This research is qualitative. Also was used the "Descriptive/ Explanatory" through contain analysis. The research method are phenomenological, conceptual and constructive theory in field of tourism industry in context of Iran, Which eventually is bound to lead to the development of tourism industry in Iran. The strategy of this research is qualitative method by using case study in the area of tourism industry in fabric of Iran. So, was introduced touristic-historical building. Then according to visitor comments was ranked. At finally was used T-Test method in order to analyzing hypothesis.

  2. WMOST v2 Case Study: Monponsett Ponds

    Science.gov (United States)

    This webinar presents an overview of the preliminary results of a case study application of EPA's Watershed Management Optimization Support Tool v2 (WMOST) for stakeholders in the Monponsett Ponds Watershed Workgroup. Monponsett Ponds is a large water system consisting of two ba...

  3. Recurrent perinatal loss: a case study.

    Science.gov (United States)

    Kavanaugh, K; Robertson, P A

    1999-01-01

    To date, investigators have not demonstrated a clear relationship between a parent's history of prior perinatal losses and intensity of grief response following a subsequent perinatal loss. Examining this relationship for low-income, African-American parents is important because they are a vulnerable population due to the high incidence of perinatal mortality in Blacks and their other life stressors that can impact on grief response and caring needs. The purpose of this case study was to examine the impact of recurrent perinatal loss on a low-income African-American parent. The research design for this study was case report, using interview data collected from a mother who had recently experienced her fourth perinatal loss, which occurred at twenty-five weeks of gestation. Transcripts from two open-ended interviews were analyzed. The theoretical framework used to guide analysis of this case study was Lazarus and Folkman's stress and coping theory. Results demonstrated that the prior perinatal losses did not appear as critical components of the way the mother responded to her most recent loss. Instead, perception of the care she received from healthcare providers and how that care related to her experiences with her one living child who was born at the same gestational age was an important determinant in how she responded to her loss. The results of this case study demonstrate the importance assessing a person's perception of their experience and those factors which contribute to the way they respond.

  4. Teaching the Holocaust through Case Study

    Science.gov (United States)

    Misco, Thomas

    2009-01-01

    This article responds to the curricular challenges teachers face with Holocaust education, including cursory treatments and a lack of focus on individual experiences. First, the author argues for a case-study approach to help students reengage concrete and complex features of the Holocaust as a point of departure for subsequent inquiry. In…

  5. Lifelong Learning in SMEs: A Case Study.

    Science.gov (United States)

    Holden, Rick; Smith, Vikki; Devins, Dave

    2002-01-01

    Learning centers using information-communications technologies were established in three British industrial estates. A case study of one organization shows the center contributed to lifelong learning and enhanced information technology training and employee confidence. Transfer of training and productivity improvements were not as clear. (Contains…

  6. It's Not Funny: A Case Study

    Science.gov (United States)

    Méndez-Morse, Sylvia

    2015-01-01

    This case study may be used with personnel supervision, school law, and other school leadership courses. It describes the behavior and actions of one teacher toward another. Student discussions can focus on supervision, workplace mobbing, workplace bullying, as well as sexual harassment. Students should focus on a school leader's role in such…

  7. Physical Science Connected Classrooms: Case Studies

    Science.gov (United States)

    Irving, Karen; Sanalan, Vehbi; Shirley, Melissa

    2009-01-01

    Case-study descriptions of secondary and middle school classrooms in diverse contexts provide examples of how teachers implement connected classroom technology to facilitate formative assessment in science instruction. Connected classroom technology refers to a networked system of handheld devices designed for classroom use. Teachers were…

  8. The Verbal Noncommunicator: A Case Study.

    Science.gov (United States)

    Fujiki, Martin; Brinton, Bonnie

    1991-01-01

    This article presents a case study of a nine-year-old male with language impairment and specific pragmatic disabilities. His interactions with an adult, a language age-matched peer, and a chronological age-matched peer were observed and analyzed to determine conversational responsiveness and assertiveness. Findings support Fey's (1986) verbal…

  9. Acoustical case studies of three green buildings

    Science.gov (United States)

    Siebein, Gary; Lilkendey, Robert; Skorski, Stephen

    2005-04-01

    Case studies of 3 green buildings with LEED certifications that required extensive acoustical retrofit work to become satisfactory work environments for their intended user groups will be used to define areas where green building design concepts and acoustical design concepts require reconciliation. Case study 1 is an office and conference center for a city environmental education agency. Large open spaces intended to collect daylight through clerestory windows provided large, reverberant volumes with few acoustic finishes that rendered them unsuitable as open office space and a conference room/auditorium. Case Study 2 describes one of the first gold LEED buildings in the southeast whose primary design concepts were so narrowly focused on thermal and lighting issues that they often worked directly against basic acoustical requirements resulting in sound levels of NC 50-55 in classrooms and faculty offices, crosstalk between classrooms and poor room acoustics. Case study 3 is an environmental education and conference center with open public areas, very high ceilings, and all reflective surfaces made from wood and other environmentally friendly materials that result in excessive loudness when the building is used by the numbers of people which it was intended to serve.

  10. Performance-Related Pay: A Case Study.

    Science.gov (United States)

    Swabe, A. I. R.

    1989-01-01

    Discusses performance-related pay and why the system was introduced, how it was negotiated, and how it has operated. The case study illustrated is in a British financial services company where the system was negotiated in 1986 and began in 1987. (JOW)

  11. Acquaintance Rape: A Case Study Approach.

    Science.gov (United States)

    Marinelli, Rosalie D.

    1994-01-01

    Describes a case study approach to acquaintance rape used in a Personal Health and Lifestyles course at the University of Nevada in Reno that allows students to discuss the characters in a scenario, an instructional process seen as less threatening than describing personal experiences. (MDM)

  12. A Case Study on Distributed Antenna Systems

    DEFF Research Database (Denmark)

    Sørensen, Troels Bundgaard

    2007-01-01

    to changing interference and traffic conditions are less common, despite their potential for increased capacity in comparison with traditional (pico)cellular based concepts. This chapter explores a case study of one indoor environment where the site-specific propagation characteristics are taken into account...

  13. Case Studies on Globalization and Money Laundering

    OpenAIRE

    Eckhard Freyer

    2008-01-01

    Financial globalization has greatly improved the efficiency of capital transfers around the world, with the cost of facilitating criminal money laundering activities. Based on case studies on conditions for money laundering in the process of globalization and transformation in Europe, are discussed the challenges that a “global financial village” must confront.

  14. A CASE STUDY OF ENVIRONMENTAL DATA MANAGEMENT

    Science.gov (United States)

    In order to support our ongoing research in watershed ecology and global climate change, we gather and analyze environmental data from several government agencies. This case study demonstrates a researcher’s approach to accessing, organizing, and using intersectoral data. T...

  15. Comparative Environmental Threat Analysis: Three Case Studies.

    Science.gov (United States)

    Latour, J. B.; Reiling, R.

    1994-01-01

    Reviews how carrying capacity for different environmental problems is operationalized. Discusses whether it is possible to compare threats, using the exceeding of carrying capacity as a yardstick. Points out problems in comparative threat analysis using three case studies: threats to European groundwater resources, threats to ecosystems in Europe,…

  16. Learning Machine Learning: A Case Study

    Science.gov (United States)

    Lavesson, N.

    2010-01-01

    This correspondence reports on a case study conducted in the Master's-level Machine Learning (ML) course at Blekinge Institute of Technology, Sweden. The students participated in a self-assessment test and a diagnostic test of prerequisite subjects, and their results on these tests are correlated with their achievement of the course's learning…

  17. Firefighter Workplace Learning: An Exploratory Case Study

    Science.gov (United States)

    Tracey, Edward A.

    2014-01-01

    Despite there being a significant amount of research investigating workplace learning, research exploring firefighter workplace learning is almost nonexistent. The purpose of this qualitative multi-case study was to explore how firefighters conceptualize, report, and practice workplace learning. The researcher also investigated how firefighters…

  18. Climate wise case study compendium: Report 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    This case study compendium is one of several Climate Wise tools available to help interested companies identify cost-effective options. Climate Wise, a private-public partnership program, is a key Federal initiative to return greenhouse gas emissions to 1990 levels by 2000.

  19. Fraternization in Accounting Firms: A Case Study

    Science.gov (United States)

    Heinze, Tim; Kizirian, Tim; Leese, Wallace

    2004-01-01

    This case study sheds light on how to avoid risks caused by manager-subordinate dating relationships (fraternization) such as employee misunderstandings, retaliation charges, favoritism complaints, wrongful termination lawsuits, and sexual harassment lawsuits, as well as associated ethical risks. Risk avoidance can be accomplished through a better…

  20. ESL and Digital Video Integration: Case Studies

    Science.gov (United States)

    Li, J., Ed.; Gromik, N., Ed.; Edwards, N., Ed.

    2013-01-01

    It should come as no surprise that digital video technology is of particular interest to English language learners; students are drawn to its visual appeal and vibrant creative potential. The seven original case studies in this book demonstrate how video can be an effective and powerful tool to create fluid, fun, interactive, and collaborative…