WorldWideScience

Sample records for case study based

  1. Study on Case-Based Fixture Design

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Fixture is an important manufacturing activity. A fixture design system based on case-based reasoning (CBR) is proposed in this paper. A new method of case representation on the basis of fixture function is presented, where the case representation is constituted of workpiece knowledge, processing feature knowledge, and fixture feature knowledge. Running the prototype system shows that the knowledge representation method, using cases, is a better way to transform and explain the design knowledge.

  2. Logistics case study based research: Towards higher quality

    DEFF Research Database (Denmark)

    Pedrosa, Alex; Näslund, Dag; Jasmand, Claudia

    2012-01-01

    analysis of 134 case study based articles published in six leading logistics and supply chain management (SCM) journals between 1998 and 2010 is used to assess and evaluate the quality of the case study based research approach as documented in these publications. Findings – This research provides an...... overview of the quality of the case study based research approach. Results show that the quality is generally low, supporting the ongoing, but empirically unsupported criticism on the quality of case study based research. The results also highlight which specific aspects authors and reviewers need to...... address to ensure high quality of the case study based research approach in published articles. Research limitations/implications – This study is limited to the analysis of published articles in six logistics and SCM journals. Further research should investigate different journals in logistics and other...

  3. Case Studies for Contract-based Systems

    OpenAIRE

    Jakob, Michal; Pěchouček, Michal; Chábera, Jiří; Miles, Simon; Luck, Michael; Oren, Nir; Kollingbaum, Martin; Holt, Camden; Vazquez, Javier; Storms, Patrick; Dehn, Martin

    2008-01-01

    Of the ways in which agent behaviour can be regulated in a multi-agent system, electronic contracting - based on explicit representation of different parties' responsibilities, and the agreement of all parties to them - has significant potential for modern industrial applications. Based on this assumption, the CONTRACT project aims to develop and apply electronic contracting and contract-based monitoring and verification techniques in real world applications. This paper presents results from ...

  4. Arts-Based Learning and Leadership Development: A Case Study

    Science.gov (United States)

    Brenner, Michael Yoel

    2010-01-01

    This qualitative case study was designed to explore how participants in an arts-based leadership development program learned to draw on their right brain capabilities in order to develop the creative competencies required to solve complex modern-day problems in new and different ways. The rationale for this study emerges from the researcher's…

  5. A Specification—Based Case Study from Test Class Framework

    Institute of Scientific and Technical Information of China (English)

    LIULing; MIAOHuai-kou

    2001-01-01

    Testing is a standard method for verification of software performance.Producing efficinet and appropriate test case is an important aspect in testing.Specification-based testing presents a method to derive test data from software specification.Because of the precision and concision of specification.the test data derived from specification can test the software efficiently and entirely.This paper demonstrates a test class framework(TCF) on a file reading case study,specifiec using Z notation,This class framework defines test case sets,providing structure to the testing process.Flexbility is preserved so that many testing strategies can be used.

  6. Predictive Software Measures based on Z Specifications - A Case Study

    Directory of Open Access Journals (Sweden)

    Andreas Bollin

    2012-07-01

    Full Text Available Estimating the effort and quality of a system is a critical step at the beginning of every software project. It is necessary to have reliable ways of calculating these measures, and, it is even better when the calculation can be done as early as possible in the development life-cycle. Having this in mind, metrics for formal specifications are examined with a view to correlations to complexity and quality-based code measures. A case study, based on a Z specification and its implementation in ADA, analyzes the practicability of these metrics as predictors.

  7. Study Paper on Test Case generation for GUI Based Testing

    CERN Document Server

    Isabella, A

    2012-01-01

    With the advent of WWW and outburst in technology and software development, testing the software became a major concern. Due to the importance of the testing phase in a software development life cycle, testing has been divided into graphical user interface (GUI) based testing, logical testing, integration testing, etc.GUI Testing has become very important as it provides more sophisticated way to interact with the software. The complexity of testing GUI increased over time. The testing needs to be performed in a way that it provides effectiveness, efficiency, increased fault detection rate and good path coverage. To cover all use cases and to provide testing for all possible (success/failure) scenarios the length of the test sequence is considered important. Intent of this paper is to study some techniques used for test case generation and process for various GUI based software applications.

  8. An Evaluation of Web-Based Case Studies in Microscopy

    Directory of Open Access Journals (Sweden)

    Susan M. Merkel

    2009-12-01

    Full Text Available It is often difficult to provide students in introductory science courses with opportunities that mimic the investigative learning experience of doing research. This is particularly true in microbiology courses where advanced microscopy techniques are expensive and difficult to do. To that end, we developed three computer-based case studies around real-life scenarios. Our goals were to: (i improve students’ understanding of advanced microscopic techniques, (ii give students practice analyzing and interpreting data, and (iii model a scientific approach to how these techniques are applied to current issues in microbiology. Each case requires students to use references and interpret actual microscopic images, thus giving them a more realistic experience than we could previously provide. We analyzed student learning and perceptions to these case studies. After doing the case studies, students were more able to apply microscopic methods to a realistic problem, thus demonstrating an understanding of how the methods are used. Students appreciated the intellectual challenges presented by having to interpret and analyze actual microscopic images. This approach has allowed us to introduce new areas of content to our course and to stimulate critical thinking skills, a difficult task in a large introductory microbiology course.

  9. Discrete Surface Modeling Based on Google Earth: A Case Study

    OpenAIRE

    Mei, Gang; Tipper, John C.; Xu, Nengxiong

    2012-01-01

    Google Earth (GE) has become a powerful tool for geological, geophysical and geographical modeling; yet GE can be accepted to acquire elevation data of terrain. In this paper, we present a real study case of building the discrete surface model (DSM) at Haut-Barr Castle in France based on the elevation data of terrain points extracted from GE using the COM API. We first locate the position of Haut-Barr Castle and determine the region of the study area, then extract elevation data of terrain at...

  10. Case Studies

    International Nuclear Information System (INIS)

    Proven options available to Sri Lanka for large scale electricity generation in the future are coal-fired thermal, oil-fired thermal and Nuclear. Four case studies for groups participated are indicated. Case study for group 1 is comparison of the three options by taking into consideration the capital and recurrent expenditure involved. Environmental effects of the three options are also given. Case study for group 2 is economic comparison of three renewable energy based power generation system. Case study for group 3 is based on energy conservation, efficiency, improvement and demand management. Assuming that a continuous saving of 20 MW of demand from 1996 onwards is effective two projects are suggested to achieve this result. Case study for group 4 is a feasibility study for hydro power development of the Kukule Ganga (river) in Sri Lanka. Participants are required to evaluate one of the three optional development concepts which are technically feasible

  11. Case Studies in Agnotology-Based Learning (Invited)

    Science.gov (United States)

    Cook, J.; Bedford, D. P.; Mandia, S. A.

    2013-12-01

    Agnotology is the study of how and why ignorance or misconceptions exist. While misconceptions are a challenge for educators, they also present an opportunity to improve climate literacy through agnotology-based learning. This involves refutational lessons that challenge misconceptions while teaching scientific concepts. I will summarize two decades of research that find refutational texts are among the most effective forms of reducing misconceptions. I will present case studies in improving climate literacy through agnotology-based learning, both in the college classroom and in public outreach promoted through mainstream and social media. I will also explore how content from the SkepticalScience.com website is being used by educators as a teaching resource. These real-world examples demonstrate effective ways to reduce misperceptions and improve climate literacy.

  12. Game Mechanic based E-Learning : A case study

    OpenAIRE

    Gåsland, Magne Matre

    2011-01-01

    This thesis presents a case study of Game Mechanic based E-Learning. This is put forward as a new approach to E-Learning that tries to mimic games to harness some of their motivational properties. A prototype system was developed as a web application, using an Agile and Lean development approach.The system was evaluated with a class at the Norwegian University of Science and Technology.This was done to give an indication of the system's ability to make work with exercises more engaging a...

  13. Discrete Surface Modeling Based on Google Earth: A Case Study

    CERN Document Server

    Mei, Gang; Xu, Nengxiong

    2012-01-01

    Google Earth (GE) has become a powerful tool for geological, geophysical and geographical modeling; yet GE can be accepted to acquire elevation data of terrain. In this paper, we present a real study case of building the discrete surface model (DSM) at Haut-Barr Castle in France based on the elevation data of terrain points extracted from GE using the COM API. We first locate the position of Haut-Barr Castle and determine the region of the study area, then extract elevation data of terrain at Haut-Barr, and thirdly create a planar triangular mesh that covers the study area and finally generate the desired DSM by calculating the elevation of vertices in the planar mesh via interpolating with Universal Kriging (UK) and Inverse Distance Weighting (IDW). The generated DSM can reflect the features of the ground surface at Haut-Barr well, and can be used for constructingthe Sealed Engineering Geological Model (SEGM) in further step.

  14. STUDY PAPER ON TEST CASE GENERATION FOR GUI BASED TESTING

    Directory of Open Access Journals (Sweden)

    Isabella

    2012-02-01

    Full Text Available With the advent of WWW and outburst in technology and software development, testing the softwarebecame a major concern. Due to the importance of the testing phase in a software development lifecycle,testing has been divided into graphical user interface (GUI based testing, logical testing, integrationtesting, etc.GUI Testing has become very important as it provides more sophisticated way to interact withthe software. The complexity of testing GUI increased over time. The testing needs to be performed in away that it provides effectiveness, efficiency, increased fault detection rate and good path coverage. Tocover all use cases and to provide testing for all possible (success/failure scenarios the length of the testsequence is considered important. Intent of this paper is to study some techniques used for test casegeneration and process for various GUI based software applications.

  15. A simulation based case study for control of DSTATCOM.

    Science.gov (United States)

    Kumar, Pradeep; Kumar, Niranjan; Akella, A K

    2014-05-01

    This paper presents a distribution static compensator (DSTATCOM) for power quality improvements in terms of harmonics and power factor correction in a three-phase four-wire distribution system. The DSTATCOM is implemented with PWM current controlled six-leg voltage source converter (VSC) and the switching patterns are generated through a novel synchronous reference frame controller (SRFC). The insulated gate bipolar transistor (IGBT) based VSC is supported by a capacitor and is controlled for the required compensation of the load current. The DSTATCOM is connected to the power system feeding nonlinear loads. Nonlinear loads include either current-source type or voltage-source type. Harmonic spectrum of the source current is compared in between without DSTATCOM and with DSTATCOM by considering both types of nonlinear loads. The SRFC based DSTATCOM system is validated through extensive simulation for diode-rectifier and unbalanced R-L loads with a case study. PMID:24656282

  16. Expanded fluid based viscosity correlation : diluted heavy oil case study

    Energy Technology Data Exchange (ETDEWEB)

    Yarranton, H.; Satyro, M.A.; Schoeggl, F. [Calgary Univ., AB (Canada). Dept. of Chemical and Petroleum Engineering

    2009-07-01

    The viscosity of pure hydrocarbons has been correlated using a simple function involving fluid density, low pressure gas viscosity and pressure. The correlation was developed based on measured densities from the NIST database. The correlation has been refit to use densities predicted from the Advanced Peng-Robinson equation of state. The usefulness of the correlation was shown for pure hydrocarbons such as n-alkanes, branched alkanes, alkenes, cyclics and aromatics as well as binary mixtures of pure hydrocarbons. This presentation included a case study on the viscosity of heavy oil diluted with solvent. The newly proposed, simple and quick method for calculating liquid and vapour viscosities was found to be suitable for incorporation into process and reservoir simulators. tabs., figs.

  17. Clinicians adopting evidence based guidelines: a case study with thromboprophylaxis

    Directory of Open Access Journals (Sweden)

    Fry Margaret

    2011-09-01

    Full Text Available Abstract Background Venous Thromboembolism (VTE is a cause of hospital mortality and managing its morbidity is associated with significant expenditure. Uptake of evidenced based guideline recommendations intended to prevent VTE in hospital settings is sub-optimal. This study was conducted to explore clinicians' attitudes and the clinical environment in which they work to understand their reluctance to adopt VTE prophylaxis guidelines. Methods Between February and November 2009, 40 hospital employed doctors from 2 Australian metropolitan hospitals were interviewed in depth. Qualitative data were analysed according to thematic methodology. Results Analysis of interviews revealed that barriers to evidence based practice include i the fragmented system of care delivery where multiple members of teams and multiple teams are responsible for each patient's care, and in the case of VTE, where everyone shares responsibility and no-one in particular is responsible; ii the culture of practice where team practice is tailored to that of the team head, and where medicine is considered an 'art' in which guidelines should be adapted to each patient rather than applied universally. Interviewees recommend clear allocation of responsibility and reminders to counteract VTE risk assessment being overlooked. Conclusions Senior clinicians are the key enablers for practice change. They will need to be convinced that guideline compliance adds value to their patient care. Then with the support of systems in the organisation designed to minimize the effects of care fragmentation, they will drive practice changes in their teams. We believe that evidence based practice is only possible with a coordinated program that addresses individual, cultural and organisational constraints.

  18. Behavior-based safety on construction sites: a case study.

    Science.gov (United States)

    Choudhry, Rafiq M

    2014-09-01

    This work presents the results of a case study and describes an important area within the field of construction safety management, namely behavior-based safety (BBS). This paper adopts and develops a management approach for safety improvements in construction site environments. A rigorous behavioral safety system and its intervention program was implemented and deployed on target construction sites. After taking a few weeks of safety behavior measurements, the project management team implemented the designed intervention and measurements were taken. Goal-setting sessions were arranged on-site with workers' participation to set realistic and attainable targets of performance. Safety performance measurements continued and the levels of performance and the targets were presented on feedback charts. Supervisors were asked to give workers recognition and praise when they acted safely or improved critical behaviors. Observers were requested to have discussions with workers, visit the site, distribute training materials to workers, and provide feedback to crews and display charts. They were required to talk to operatives in the presence of line managers. It was necessary to develop awareness and understanding of what was being measured. In the process, operatives learned how to act safely when conducting site tasks using the designed checklists. Current weekly scores were discussed in the weekly safety meetings and other operational site meetings with emphasis on how to achieve set targets. The reliability of the safety performance measures taken by the company's observers was monitored. A clear increase in safety performance level was achieved across all categories: personal protective equipment; housekeeping; access to heights; plant and equipment, and scaffolding. The research reveals that scores of safety performance at one project improved from 86% (at the end of 3rd week) to 92.9% during the 9th week. The results of intervention demonstrated large decreases in

  19. Success Factors in Offset Deals: A Case Study Based Examination

    Directory of Open Access Journals (Sweden)

    Heinz Kirchwehm

    2014-04-01

    Full Text Available The requests for offset obligations occurs primarily in the area of arms imports and covers the full range of industrial and commercial benefits that companies provide to foreign governments as inducements or conditions for the purchase of military goods and services. Increasingly, all major contracts ask for offset obligations. They are now key differentiators in major contracts and it is a fast growing market. For the suppliers, offsets are a key differentiator in earning new business and therefore should be accepted that much accurateness is put on the successful execution of the offset projects. Nevertheless, it comes to problems during the project phase and sometimes we’ve the situation that a offset project failed. The aim of this paper is to exam which success- giving factors are exists in the offset related interaction between buyer, seller and participating industry. The data for this investigation were obtained from secondary sources which were mainly accessible via internet. After data collection, an analysis was performed which was based on the context of this paper and also in connection with the chosen case study: Saudi Arabia. As a result of this analysis can be derived several success factors, which could be also seen as the foundation for an optimized execution of offset obligations. The paper concludes with a reflection of the investigation approach and as well with a classification of the subject offset. Furthermore the results of the analyzes are summarized and an outlook for further researches is given.

  20. Post stroke rehabilitation based on SMART goals: a case study

    Directory of Open Access Journals (Sweden)

    Amir-ur Rehman

    2014-02-01

    Full Text Available Post stroke rehabilitation has been consistently reported in physiotherapy as being difficult to manage and limiting to rehabilitation outcome. It is reported that the first few months post stroke are crucial for rehabilitation to reach a maximum potential. However, after this period further recovery is unlikely. Specific, measurable, achievable, realistic, and time-framed (SMART goals are used for goal setting for rehabilitation. They can provide coordination between a multidisciplinary team to develop a plan for the individual needs of patients. This case study explored the use of SMART goals, which are often not used in a rehabilitation setting due to being time-consuming and difficult to create. This case report provides the first evidence that SMART goals may serve as a powerful tool for rehabilitation following stroke. The case study illustrates the clinical role of physiotherapists in the management of a patient with stroke. [J Exp Integr Med 2014; 4(1.000: 71-73

  1. Adaptation Knowledge Acquisition: a Case Study for Case-Based Decision Support in Oncology

    OpenAIRE

    D'Aquin, Mathieu; Lieber, Jean; Napoli, Amedeo

    2006-01-01

    Kasimir is a case-based decision support system in the domain of breast cancer treatment. For this system, a problem is given by the description of a patient and a solution is a set of therapeutic decisions. Given a target problem, Kasimir provides several suggestions of solutions, based on several justified adaptations of source cases. Such adaptation processes are based on adaptation knowledge. The acquisition of this kind of knowledge from experts is presented in this paper. It is shown ho...

  2. Study on Measuring System of Casing Machine Based on PLC

    Directory of Open Access Journals (Sweden)

    Huiqiang Wang

    2014-05-01

    Full Text Available According to the technology requirements of measurement for animal casing, in this paper, we use PLC and touch screen as the control core, the electromechanical integration design ideas to research the methods and principles for casing measure, and analyze the mechanical structures and mechanical characteristics of casing machine. As the control core, the programmable logic controller (PLC ensures that the whole control system has high precision, high stability, high reliability during the operation time. Through PLC and touch screen well match with PLC which make the casing machine more convenient to operate the whole system. The configuration software form has a brief and intuitive interface on touch screen which makes it easy to use. The mechanical structure and control system of this casing machine are more stable, more reliable and with high anti-interference ability, and satisfies various requirements for animal casings, easy and convenient to operate.

  3. Study on Measuring System of Casing Machine Based on PLC

    OpenAIRE

    Huiqiang Wang; Yanqiu Xing; Weilian Sun

    2014-01-01

    According to the technology requirements of measurement for animal casing, in this paper, we use PLC and touch screen as the control core, the electromechanical integration design ideas to research the methods and principles for casing measure, and analyze the mechanical structures and mechanical characteristics of casing machine. As the control core, the programmable logic controller (PLC) ensures that the whole control system has high precision, high stability, high reliability during the o...

  4. Carrying capacity based regional EIA in Orissa- a case study

    International Nuclear Information System (INIS)

    The development of an industrial complex in Orissa for iron and steel sector along with associated infrastructure may lead to all round development in the region with significant impact on the environment. Hence, carrying capacity based regional EIA is conducted to assess whether the environment is able to sustain such development activities. To assess the sustainability, release analysis is needed both from physical and living system. Whenever major industries are located in a region necessary secondary development also result including network of roads, railways with the transport load and all these have combined effect due to the releases and its consequences. The impact evaluation is dependent on the size, type of major industries with secondary developments. In the study region detailed base line data is generated and recommended methodology is followed to estimate supportive capacity and assimilative capacity

  5. Dynamics of IGBT based PWM Converter A Case Study

    Directory of Open Access Journals (Sweden)

    Vijay Shukla

    2012-04-01

    Full Text Available Optimizing the efficiency and dynamics of power converters is a critical tradeoff in power electronics. The increase of switching frequency can improve the dynamics of power converters, but theefficiency may be degraded as well as the switching losses. As power semiconductor devices like diodes, MOSFETS, IGBTs, Thyristors, BJTs have their own characterstics and dynamic responses. It is desired toanalyze and observe the dynamics of different semiconductor devices before they actually employed in the model. Inclusion of different PWM techniques help in the removal of power line interferences like harmonic losses, unwanted ripples, chopped frequencies, spikes. In this paper, we have studied and analyzed the dynamics of IGBT based PWM converter with subjected to different conditions like transient state, steady state feeding the RLC load. Snubber circuits are used to reduce the switching losses. The IGBT based PWM converter reflects the better dynamics with improved efficiency and reduced harmonics as compared to some other power semiconductor devices when FFT is performed and subjected to standard parameterized RLC load understeady state and transient analysis.

  6. A CASE STUDY IN PROJECT BASED LEARNING USING FLOW VISUALISATION

    Directory of Open Access Journals (Sweden)

    MUSHTAK AL-ATABI

    2007-12-01

    Full Text Available Engineering Design modules, usually introduced in the first and second year’s undergraduate Mechanical Engineering courses, present a unique platform to practice the Project Based Learning (PBL. PBL is a widely accepted technique that can be used to achieve two major educational goals; affirming the theoretical principles studied in other modules and developing the professional skill essential for graduates such as team working and effective communication skills. In this paper we describe the use of PBL to enhance the understanding of turbulence, a classical problem in fluid mechanics. The project is carried out in the “Mechanical Engineering Design & Professional Skills” Module, which requires the students to construct the Prandtl recirculating water channel. The skills and knowledge involved not only fluid mechanics, but design, material selections and engineering mechanics, making it a truly multi-disciplinary project.

  7. A case study of the residual-based cointegration procedure

    Directory of Open Access Journals (Sweden)

    Riccardo Biondini

    2003-01-01

    Full Text Available The study of long-run equilibrium processes is a significant component of economic and finance theory. The Johansen technique for identifying the existence of such long-run stationary equilibrium conditions among financial time series allows the identification of all potential linearly independent cointegrating vectors within a given system of eligible financial time series. The practical application of the technique may be restricted, however, by the pre-condition that the underlying data generating process fits a finite-order vector autoregression (VAR model with white noise. This paper studies an alternative method for determining cointegrating relationships without such a pre-condition. The method is simple to implement through commonly available statistical packages. This ‘residual-based cointegration’ (RBC technique uses the relationship between cointegration and univariate Box-Jenkins ARIMA models to identify cointegrating vectors through the rank of the covariance matrix of the residual processes which result from the fitting of univariate ARIMA models. The RBC approach for identifying multivariate cointegrating vectors is explained and then demonstrated through simulated examples. The RBC and Johansen techniques are then both implemented using several real-life financial time series.

  8. Epidemiological study of road traffic accident cases in Greater Noida: Hospital Based Study

    Directory of Open Access Journals (Sweden)

    Rupali Roy

    2014-09-01

    Full Text Available Introduction: Road accidents are associated with numerous problems each of which needs to be addressed separately [1]. Accidents, therefore, can be studied in terms of agent, host and environmental factors and epidemiologically classified into time, place and person distribution [2]. Objectives: 1.To assess the prevalence of RTAs coming to hospital and 2.To know the epidemiological factors related to RTAs and associated prevalence in hospital based study. Methodology: This cross sectional study was conducted at SMSR, Gr Noida, in 2012. The study group consisted of all the RTA victims reporting to casualty in the last one year. The victims of the accidents were interviewed on a pretested semi structured performa. Results: In that one year period total number of reported accident cases was 144. The age groups of the study subjects were between 13-65 years. Out of total study subjects, only 16 were female. Again out of the total accident cases 45% were attended by police and of all injured, 45.8% were driver by occupation (7% without driving license. Among these drivers, 11% were not attentive during driving because of various reasons. Ambulance services had reached in 46.5% cases. Fracture was the most common type (60% of injury among all types of injuries. Among the applicable population only 33% wore helmet or seat belts. Conclusions: Only half of the total accident cases were attended by police and again only half of them received ambulance services. One third injuries were because of not wearing seat belt and helmets.

  9. Evaluation Model for Experts Social Networks (Based on Case Study

    Directory of Open Access Journals (Sweden)

    Fatemeh Saghafi

    2012-05-01

    Full Text Available Every Social network is considered as a structured Society constitute of individual or organizational group which are associated together within different type of dependency. The most important elements influence the success of such social network is the level of interest for sharing the information. This article addresses the important factors on assessment of Intellectual National Internet Network(ININ. For assessment we propose Enhanced technology acceptance model which we deployed by extending Davis TAM(technology acceptance model.ININ is a web base sites for think thanking of researchers which is acting within a four month at RICT(Research institute of ICT and the number of 214 ICT researchers distribute and delivered their experience. The result shows that in intellectual society, Intelligence has higher values to be disseminated and higher inspiration is needed for its successful sharing in new generation of Information technology.

  10. A Case Study: Problem-Based Learning for Civil Engineering Students in Transportation Courses

    Science.gov (United States)

    Ahern, A. A.

    2010-01-01

    This paper describes two case studies where problem-based learning (PBL) has been introduced to undergraduate civil engineering students in University College Dublin. PBL has recently been put in place in the penultimate and final year transport engineering classes in the civil engineering degree in University College Dublin. In this case study,…

  11. A case study of the residual-based cointegration procedure

    OpenAIRE

    Biondini, Riccardo; Lin, Yan-Xia; Mccrae, Michael

    2003-01-01

    The study of long-run equilibrium processes is a significant component of economic and finance theory. The Johansen technique for identifying the existence of such long-run stationary equilibrium conditions among financial time series allows the identification of all potential linearly independent cointegrating vectors within a given system of eligible financial time series. The practical application of the technique may be restricted, however, by the pre-condition that the underlying data ge...

  12. Population-based case-control study of breast cancer in Albania

    OpenAIRE

    Pajenga E.; Rexha T.; Çeliku S.; Mariani E.

    2013-01-01

    In Albania, breast cancer is an important cause of death among women, with increasing incidence from 65 cases in 1970, to 400 cases in 2007. This is the first study concerning breast cancer risk factors in Albania. We used a population-based case-control study of 948 women with breast cancer compared with 1019 controls recruited from other hospitals through random selection. Early age at menarche was found to be a significantly strong risk factor during the pre- and postmenopausal group...

  13. Problem-based case study to enhance critical thinking in student nurses

    Directory of Open Access Journals (Sweden)

    NM Mogale

    2001-09-01

    Full Text Available The use of traditional teaching methods, for example the lecture method, does not stimulate critical thinking in student nurses. This problem can be solved by the utilisation of problem-based case study in the classroom/clinical setting. The purpose of this study is to describe guidelines for the implementation of problem-based case study in a clinical setting among first year, comprehensive course students at the Northern Province College of Nursing: Sovenga campus. The research design of this study was qualitative, explorative, descriptive and contextual and was conducted in the following phases: Phase 1: The development and implementation of a program for problem-based case study in the clinical setting; Phase II: The experiences of student nurses who were exposed to problem-based case study in the clinical setting; Phase III: The perceptions of tutors regarding the implementation of problem-based case study in the clinical setting (focus group, and; ase IV: Guidelines for the implementation of problem-based case study. The data from Phases I, II and III were used to formulate guidelines for the implementation of problem-based case study. The sample group consisted of all 69 first year student nurses at the Northern Province College of Nursing: Sovenga campus and ten tutors teaching clinical courses at the same campus. The Tesch (1990 approach is used for data analysis. Nine guidelines for the implementation of a problem-based case study approach were formulated and recommendations for development of an instrument to measure critical thinking in nursing were recommended.

  14. Development and Evaluation of a Multi-Institutional Case Studies-Based Course in Food Safety

    Science.gov (United States)

    Pleitner, Aaron M.; Chapin, Travis K.; Hammons, Susan R.; Stelten, Anna Van; Nightingale, Kendra K.; Wiedmann, Martin; Johnston, Lynette M.; Oliver, Haley F.

    2015-01-01

    Developing novel, engaging courses in food safety is necessary to train professionals in this discipline. Courses that are interactive and case-based encourage development of critical thinking skills necessary for identifying and preventing foodborne disease outbreaks. The purpose of this study was to assess the efficacy of a case study…

  15. Feasibility Study of EO SARs as Opportunity Illuminators in Passive Radars: PAZ-Based Case Study

    Directory of Open Access Journals (Sweden)

    Jose-Luis Bárcena-Humanes

    2015-11-01

    Full Text Available Passive radars exploit the signal transmitted by other systems, known as opportunity illuminators (OIs, instead of using their own transmitter. Due to its almost total invulnerability to natural disasters or physical attacks, satellite OIs are of special interest. In this line, a feasibility study of Earth Observation Synthetic Aperture Radar (EO SAR systems as OIs is carried out taking into consideration signal waveform, availability, bistatic geometry, instrumented coverage area and incident power density. A case study based on the use of PAZ, the first Spanish EO SAR, is presented. PAZ transmitted waveform, operation modes, orbit characteristics and antenna and transmitter parameters are analyzed to estimate potential coverages and resolutions. The study concludes that, due to its working in on-demand operating mode, passive radars based on PAZ-type illuminators can be proposed as complementing tools during the sensor commissioning phase, for system maintenance and for improving its performance by providing additional information about the area of interest and/or increasing the data updating speed, exploiting other sensors during the time PAZ is not available.

  16. Antioxidants and breast cancer risk- a population-based case-control study in Canada

    OpenAIRE

    Morrison Howard; Gibbons Laurie; Zhou Jia; Pan Sai Yi; Wen Shi Wu

    2011-01-01

    Abstract Background The effect of antioxidants on breast cancer is still controversial. Our objective was to assess the association between antioxidants and breast cancer risk in a large population-based case-control study. Methods The study population included 2,362 cases with pathologically confirmed incident breast cancer (866 premenopausal and 1,496 postmenopausal) and 2,462 controls in Canada. Intakes of antioxidants from diet and from supplementation as well as other potential risk fact...

  17. Integrating Web-Based Applications into Aged Care: Two Case Studies and Discussion.

    Science.gov (United States)

    Rehm, Imogen C; Musić, Selma; Carlsson, Anthony; Scanlan, Faye; Silver, Mark; Bhar, Sunil S

    2016-09-01

    In anticipation of the growing need for adequate mental health care for older adults in residential aged care facilities, psychologists are challenged to overcome several barriers that impede the uptake and delivery of their services in such settings. Information and communication technologies (ICT) have strong potential to overcome some of these barriers by supporting the delivery of evidence-based psychosocial treatments for common psychogeriatric issues. This paper presents two case studies that illustrate when and how psychologists can use various ICT applications (e.g., tablet devices, web-based applications) integrated with cognitive behavioural and reminiscence-based therapies. Both case studies demonstrate that ICT can effectively support the therapeutic alliance, enhance therapeutic engagement, and individualize treatment delivery to accommodate the needs of elderly patients. It is hoped that these case studies will encourage clinicians to consider using ICT to augment therapy with their elderly patients. PMID:27073103

  18. Behavioural Comorbidity in Tanzanian Children with Epilepsy: A Community-Based Case-Control Study

    Science.gov (United States)

    Burton, Kathryn; Rogathe, Jane; Hunter, Ewan; Burton, Matthew; Swai, Mark; Todd, Jim; Neville, Brian; Walker, Richard; Newton, Charles

    2011-01-01

    Aim: The aim of this study was to define the prevalence of and risk factors for behavioural disorders in children with epilepsy from a rural district of Tanzania by conducting a community-based case-control study. Method: One hundred and twelve children aged 6 to 14 years (55 males, 57 females; median age 12y) with active epilepsy (at least two…

  19. The MORPG-Based Learning System for Multiple Courses: A Case Study on Computer Science Curriculum

    Science.gov (United States)

    Liu, Kuo-Yu

    2015-01-01

    This study aimed at developing a Multiplayer Online Role Playing Game-based (MORPG) Learning system which enabled instructors to construct a game scenario and manage sharable and reusable learning content for multiple courses. It used the curriculum of "Introduction to Computer Science" as a study case to assess students' learning…

  20. Project Based Learning for Life Skill Building in 12th Grade Social Studies Classrooms: A Case Study

    Science.gov (United States)

    Zimmerman, Daniele C.

    2010-01-01

    Based on the assumption that project based learning (PBL) in 12th grade social studies classrooms contributes to the development of life skills for high school seniors in this advanced and globalized time, this research will investigate student experiences with PBL methods for helping them acquire skills along with a case study of a successful PBL…

  1. Case Base Maintenance Approach.

    OpenAIRE

    Haouchine, Mohamed-Karim; Chebel-Morello, Brigitte; Zerhouni, Noureddine

    2007-01-01

    Case base Maintenance is an active Case Based Reasoning research area. The main stream focuses on the method for reducing the size of the case-base while maintaining case-base competence. This paper gives an overview of these works, and proposes a case deletion strategy based on competence criteria using a novel approach. The proposed method, even if inspired from existing literature, combines an algorithm with a Competence Metric (CM). A series of tests are conducted using two standards data...

  2. Faith and Moral Development: A Case Study of a Jail Faith-Based Correctional Education Program

    Science.gov (United States)

    Swanson, Karen

    2009-01-01

    Increasingly, faith-based programs have provided curriculum in correctional facilities to meet the challenge of rehabilitating offenders. To attempt to identify the impact of such instruction, this qualitative case study examines the faith and moral development of the participants in one such program. Through interviews, observations, document…

  3. Competency-Based Vocational Education. A Case Study. FEU/PICKUP Project Report.

    Science.gov (United States)

    Hermann, G. D.; Kenyon, R. J.

    This document describes a case study of a competency-based vocational education (CBVE) project. An introduction outlines the nature of CBVE and places it in the context of vocational competence. This section also describes a rationale for how CBVE relates to the individual, to access, and to the recognition of previous learning. The features and…

  4. Adapting Learning Activities: a Case Study of IMS LD based Script and Tooling

    NARCIS (Netherlands)

    Miao, Yongwu

    2009-01-01

    Miao, Y. (2009). Adapting Learning Activities: a Case Study of IMS LD based Script and Tooling. Presentation at workshop "Adapting Activities Modeled by CSCL Scripts" of the 8th International Conference “Computer Supported Collaborative Learning” (CSCL’09). June, 8-13, 2009, Rhodes, Greece.

  5. Adapting Learning Activities: a Case Study of IMS LD based Script and Tooling

    NARCIS (Netherlands)

    Miao, Yongwu

    2009-01-01

    Miao, Y. (2009). Adapting Learning Activities: a Case Study of IMS LD based Script and Tooling. Paper presented at workshop "Adapting Activities Modeled by CSCL Scripts" of the 8th International Conference “Computer Supported Collaborative Learning” (CSCL’09). June, 8-13, 2009, Rhodes, Greece.

  6. Ecological bases for the forestry of the natural forest, Case study of the Catival (Prioretum copaiferae)

    International Nuclear Information System (INIS)

    A first development is presented for Colombia of the ecological bases for the forestry by means of the case study of the Catival consortium (prioretum copaiferae); recapturing the results of the investigations carried out for more of 16 years for the National Corporation of Investigation and Forestall Development-CONIF and the company Pizano adding the achievements of other investigations

  7. Postgraduate Work-Based Learning Programmes in English Higher Education: Exploring Case Studies of Organizational Practice

    Science.gov (United States)

    Smith, Paul; Preece, David

    2009-01-01

    The first part of the paper outlines and discusses the nature of work-based learning (WBL) and WBL programmes, and the overall direction of government strategy towards WBL programmes in Higher Education (HE) in England, with particular reference to postgraduate programmes, policy documents, and the WBL literature. Drawing upon case study research,…

  8. Influence of social factors on avoidable mortality: a hospital-based case-control study.

    OpenAIRE

    Bautista, Daniel; Alfonso, José Luis; Corella, Dolores; Saiz, Carmen

    2005-01-01

    OBJECTIVE: The effect of socioeconomic factors on avoidable mortality at an individual level is not well known, since most studies showing this association are based on aggregate data. The purpose of this study was to determine socioeconomic differences between those patients who die of avoidable causes and those who do not die. METHODS: A matched case-control study was carried out regarding in-hospital avoidable mortality (Holland's medical care indicators) that occurred in a university hosp...

  9. Challenges in Mentalization–Based Group Therapy (MBT-G) : A Video-based Explorative Case Study

    OpenAIRE

    Inderhaug, Tryggve Sagen

    2013-01-01

    This paper presents a video-based explorative case study of therapeutic challenges in mentalization-based group therapy (MBT-G) for patients with borderline-type problems. Employing qualitative methodology, we explored a MBT group as part of routine psychiatric care at a Psychiatric District Centre (naturalistic study). Several phenomena emerged as important in understanding the therapists’ struggle to construe the group in a manner that foster mentalization. First and foremost, the main chal...

  10. Feasibility report: Delivering case-study based learning using artificial intelligence and gaming technologies

    OpenAIRE

    Cresswell, Stephen; Prigmore, Martyn

    2008-01-01

    This document describes an investigation into the technical feasibility of a game to support learning based on case studies. Information systems students using the game will conduct fact-finding interviews with virtual characters. We survey relevant technologies in computational linguistics and games. We assess the applicability of the various approaches and propose an architecture for the game based on existing techniques. We propose a phased development plan for the development of the game.

  11. Managing Labor on Dairy Farms: A Resource-Based Perspective with Evidence from Case Studies

    OpenAIRE

    Mugera, Amin W.; Bitsch, Vera

    2005-01-01

    Labor management practices in agriculture are a marginally and fragmentally researched subject with limited theoretical background in agricultural economics. The resource-based theory is proposed as a framework to analyze labor management on farms and its application discussed with evidence of six case studies. In-depth interviews with farm managers, supervisors, and non-supervisory employees provide data to illustrate the provisions of the resource-based theory. The theory requires heterogen...

  12. Web-based Peer Assessment: A Case Study with Civil Engineering Students

    OpenAIRE

    Gonçalo Cruz; Caroline Dominguez; Ana Maia; Daniela Pedrosa; Gordon Grams

    2013-01-01

    Peer-assessed online collaborative writing is of growing importance for higher education. Based on the quantitative and qualitative analysis of collected data, this work presents the results of a case study in a graduate civil engineering course at the University of Trás-os-Montes e Alto Douro, Vila Real, Portugal. After an overall presentation of the learning activity, it examines students’ attitudes towards web-based peer assessment and identifies which factors are rela...

  13. A case study to estimate costs using Neural Networks and regression based models

    Directory of Open Access Journals (Sweden)

    Nadia Bhuiyan

    2012-07-01

    Full Text Available Bombardier Aerospace’s high performance aircrafts and services set the utmost standard for the Aerospace industry. A case study in collaboration with Bombardier Aerospace is conducted in order to estimate the target cost of a landing gear. More precisely, the study uses both parametric model and neural network models to estimate the cost of main landing gears, a major aircraft commodity. A comparative analysis between the parametric based model and those upon neural networks model will be considered in order to determine the most accurate method to predict the cost of a main landing gear. Several trials are presented for the design and use of the neural network model. The analysis for the case under study shows the flexibility in the design of the neural network model. Furthermore, the performance of the neural network model is deemed superior to the parametric models for this case study.

  14. Population-based case-control study of breast cancer in Albania

    Directory of Open Access Journals (Sweden)

    Pajenga E.

    2013-01-01

    Full Text Available In Albania, breast cancer is an important cause of death among women, with increasing incidence from 65 cases in 1970, to 400 cases in 2007. This is the first study concerning breast cancer risk factors in Albania. We used a population-based case-control study of 948 women with breast cancer compared with 1019 controls recruited from other hospitals through random selection. Early age at menarche was found to be a significantly strong risk factor during the pre- and postmenopausal groups with OR 10.04 and 12.1, respectively. In addition, nulliparity is associated with higher risk while abortion did not indicate any influence in the multivariate model. The findings from this study have shown that reproductive and menstrual variables are significant predictors of breast cancer risk in Albanian women, as seen in studies of other western countries.

  15. Regional science-based clusters:a case study of three European concentrations

    OpenAIRE

    Teräs, J. (Jukka)

    2008-01-01

    Abstract The aim of this thesis is to provide an improved understanding of the structural characteristics and the dynamic evolution of regional science-based clusters. The study is based on an in-depth comparison of three non-metropolitan science-based clusters: Oulu in Finland, Luleå in Sweden, and Pisa in Italy. This thesis is the result of a qualitative multiple-case study consisting of in-depth interviews with cluster decision-makers and experts in Finland, Sweden and Italy. The thesi...

  16. Birth outcomes of patients with isolated anorectal malformations: A population-based case-control study.

    Science.gov (United States)

    Vermes, Gabor; László, Daniel; Czeizel, Andrew E; Ács, Nándor

    2016-01-01

    In most patients affected by isolated anorectal malformation (IARM) the etiology is largely unknown. Thus, the aim of our project was to analyze possible risk factors for IARM. In the first step, birth outcomes of cases with IARM were analyzed on the basis of maternal socio-demographic variables, and these data are presented in this paper. Gestational age at delivery, birthweight, preterm birth, low birthweight and small for gestational age of cases with IARM were evaluated in the function of maternal age, birth/pregnancy order, marital and employment status of mothers in the population-based large dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1996. The study samples included 231 live-born cases with IARM, 361 matched and 38 151 population controls without any defect. IARMs are more frequent in males, twins and newborn infants with low birthweight and small-for-gestational-age, the latter being the consequence of intrauterine growth restriction. In addition, mothers of cases were younger but with higher birth order, and had lower socio-economic status. These maternal variables are characteristic for the gypsy population in Hungary. The higher proportion of gypsy women among the mothers of cases with IARM was confirmed during the home visits of the study. Male sex and intrauterine growth restriction of cases, in addition to low socioeconomic status and gypsy origin of mothers may have a role in the risk of IARMs. PMID:26259501

  17. Quantification of construction waste prevented by BIM-based design validation: Case studies in South Korea.

    Science.gov (United States)

    Won, Jongsung; Cheng, Jack C P; Lee, Ghang

    2016-03-01

    Waste generated in construction and demolition processes comprised around 50% of the solid waste in South Korea in 2013. Many cases show that design validation based on building information modeling (BIM) is an effective means to reduce the amount of construction waste since construction waste is mainly generated due to improper design and unexpected changes in the design and construction phases. However, the amount of construction waste that could be avoided by adopting BIM-based design validation has been unknown. This paper aims to estimate the amount of construction waste prevented by a BIM-based design validation process based on the amount of construction waste that might be generated due to design errors. Two project cases in South Korea were studied in this paper, with 381 and 136 design errors detected, respectively during the BIM-based design validation. Each design error was categorized according to its cause and the likelihood of detection before construction. The case studies show that BIM-based design validation could prevent 4.3-15.2% of construction waste that might have been generated without using BIM. PMID:26754615

  18. Body Mass Index, Smoking and Hypertensive Disorders during Pregnancy: A Population Based Case-Control Study

    OpenAIRE

    Gudnadóttir, Thuridur A.; Bateman, Brian T.; Hernádez-Díaz, Sonia; Luque-Fernandez, Miguel Angel; Valdimarsdottir, Unnur; Zoega, Helga

    2016-01-01

    While obesity is an indicated risk factor for hypertensive disorders of pregnancy, smoking during pregnancy has been shown to be inversely associated with the development of preeclampsia and gestational hypertension. The purpose of this study was to investigate the combined effects of high body mass index and smoking on hypertensive disorders during pregnancy. This was a case-control study based on national registers, nested within all pregnancies in Iceland 1989–2004, resulting in birth at t...

  19. Body Mass Index, Smoking and Hypertensive Disorders during Pregnancy: A Population Based Case-Control Study.

    OpenAIRE

    Gudnadóttir, TA; Bateman, BT; Hernádez-Díaz, S; Luque-Fernandez, MA; Valdimarsdottir, U; Zoega, H

    2016-01-01

    While obesity is an indicated risk factor for hypertensive disorders of pregnancy, smoking during pregnancy has been shown to be inversely associated with the development of preeclampsia and gestational hypertension. The purpose of this study was to investigate the combined effects of high body mass index and smoking on hypertensive disorders during pregnancy. This was a case-control study based on national registers, nested within all pregnancies in Iceland 1989-2004, resulting in birth at t...

  20. A case study to estimate costs using Neural Networks and regression based models

    OpenAIRE

    Nadia Bhuiyan; Adil Salam; Fantahun M. Defersha

    2012-01-01

    Bombardier Aerospace’s high performance aircrafts and services set the utmost standard for the Aerospace industry. A case study in collaboration with Bombardier Aerospace is conducted in order to estimate the target cost of a landing gear. More precisely, the study uses both parametric model and neural network models to estimate the cost of main landing gears, a major aircraft commodity. A comparative analysis between the parametric based model and those upon neural networks model will be con...

  1. Performance-Based Pay as a Motivational Tool for Achieving Organisational Performance: An Exploratory Case Study

    OpenAIRE

    Francis Boachie-Mensah; Ophelia Delali Dogbe

    2011-01-01

    The issue of employees’ performance in furtherance of organisational objectives has occupied managementattention for long. Differences in levels of performance have been attributed to differences in skills and abilitieson the one hand, and to different theories of money on the other. This study examined the issue ofperformance-based pay as a motivational tool for achieving organisational performance, using the situation in amanufacturing company in Ghana as a case study. The main objective of...

  2. Risk factors for homicide victimization in post-genocide Rwanda : a population - based case- control study

    OpenAIRE

    Rubanzana, Wilson; Ntaganira, Joseph; Freeman, Michael D; Hedt-Gauthier, Bethany L.

    2015-01-01

    Background: Homicide is one of the leading causes of mortality in the World. Homicide risk factors vary significantly between countries and regions. In Rwanda, data on homicide victimization is unreliable because no standardized surveillance system exists. This study was undertaken to identify the risk factors for homicide victimization in Rwanda with particular attention on the latent effects of the 1994 genocide. Methods: A population-based matched case-control study was conducted, with sub...

  3. Rehabilitation of Masonry Buildings Using Seismic Isolation Systems in the BaseCase Study

    OpenAIRE

    Pintican, Maria Nicoleta Roman; Faur, Andrei; Dumitran, Mihaela; Iernuţan, Răzvan

    2014-01-01

    This paper aims to highlight the importance and efficiency of the rehabilitation of old buildings using an alternative to the classic rehabilitation, namely seismic isolation in the base. The method is efficient and will not interfer in the architecture and structure. The case study was conducted on a church that has a brick masonry structure. The structural analysis was pergormed by using SAP2000 soft, as for the study we used rubber bearings with metal inserts. The modeling was performed bo...

  4. Using Web-Based, Group Communication Systems to Support Case Study Learning at a Distance

    Directory of Open Access Journals (Sweden)

    Liam Rourke

    2002-10-01

    Full Text Available This study explored the capacity of Web-based, group communication systems to support case-based teaching and learning. Eleven graduate students studying at a distance were divided into three groups to collaborate on a case study using either a synchronous voice, an asynchronous voice, or a synchronous text communication system. Participants kept a detailed log of the time they spent on various activities, wrote a 1,500-word reflection on their experience, and participated in a group interview. Analysis of these data reveals that each group supplemented the system that had been assigned to them with additional communication systems in order to complete the project. Each of these systems were used strategically: email was used to share files and arrange meetings, and synchronous voice systems were used to brainstorm and make decisions. Learning achievement was high across groups and students enjoyed collaborating with others on a concrete task.

  5. Population-based case control study of the safety of sulfasalazine use during pregnancy

    DEFF Research Database (Denmark)

    Nørgård, Bente; Czeizel, A.E.; Rockenbauer, M.;

    2001-01-01

    Background: We studied the human teratogenic risk of sulfasalazine because this drug interferes with folate metabolism. Methods: Case control study within the Hungarian Case Control Surveillance of Congenital Abnormalities, 1980–1996; based on 22 865 new-born infants or foetuses with congenital...... abnormalities, and 38 151 babies without any detected congenital abnormalities (control group). Results: Seventeen pregnant women (0.07%) were treated with sulfasalazine in the case group, and 26 (0.07%) in the control group. The overall adjusted adds ratio of congenital abnormalities after sulfasalazine...... treatment was odds ratio=1.2 (95% confidence interval: 0.6–2.1). None of the analyses indicated any significant increased prevalence of selected congenital abnormalities among the exposed compared with the not exposed. Conclusions: We found no significant increased prevalence of selected congenital...

  6. The Effectiveness of a Case Study-Based First-Year Biology Class at a Black Women's College

    Science.gov (United States)

    Pai, Aditi; Benning, Tracy; Woods, Natasha; McGinnis, Gene; Chu, Joanne; Netherton, Josh; Bauerle, Cynthia

    2010-01-01

    The authors used a case study-based approach in the introductory biology course at Spelman College. The course taught to entering freshmen was divided into three modules--ecology, evolution, and biodiversity, each designed around a case study. They noted that (1) case study teaching was dramatically more effective than the traditional lecture…

  7. Inquiry-based Science Instruction in High School Biology Courses: A Multiple Case Study

    Science.gov (United States)

    Aso, Eze

    A lack of research exists about how secondary school science teachers use inquiry-based instruction to improve student learning. The purpose of this qualitative study was to explore how science teachers used inquiry-based instruction to improve student learning in high school biology courses. The conceptual framework was based on Banchi and Bell's model of increasing levels of complexity for inquiry-based instruction. A multiple case study research design was conducted of biology programs at 3 high schools in an urban school district in the northeastern region of the United States. Participants included 2 biology teachers from each of the 3 high schools. Data were collected from individual interviews with biology teachers, observations of lessons in biology, and documents related to state standards, assessments, and professional development. The first level of data analysis involved coding and categorizing the interview and observation data. A content analysis was used for the documents. The second level of data analysis involved examining data across all sources and all cases for themes and discrepancies. According to study findings, biology teachers used confirmation, structure, and guided inquiry to improve student learning. However, they found open inquiry challenging and frustrating to implement because professional development about scaffolding of instruction over time was needed, and students' reading and writing skills needed to improve. This study contributes to positive social change by providing educators and researchers with a deeper understanding about how to scaffold levels of inquiry-based science instruction in order to help students become scientifically literate citizens.

  8. Student-centered Role-based Case Study Model to Improve Learning in Decision Support Systems

    Directory of Open Access Journals (Sweden)

    Farrukh Nadeem

    2014-10-01

    Full Text Available One of the important learning objectives of our bachelor course on "Techniques in Decision Support Systems" is to develop understanding of core decision making process in real-life business situations. The conventional teaching methods are unable to explain complexities of real-life business. Although the classroom discussions can be effective to understand general factors, such as opportunity cost, return on investment, etc. affecting business decisions, the effects of factors like dynamic business environment, incomplete information, time pressure etc. can not be truly explained through such simple discussions. In this paper, we describe our experience of adopting student-centered, role-based, case study to deal with this situation. The interactive case-based study not only provided students with experiential learning, but also gave them liberty to test their thoughts. As a result, we observed improved students' learning as well as improved grades. In addition, this approach made classes more dynamic and interesting.

  9. Acceptance of routine or case-based inquiry for intimate partner violence: a mixed method study

    OpenAIRE

    H. Stöckl; Hertlein, L; Himsl, I; Ditsch, N; C. Blume; Hasbargen, U; Friese, K.; Stöckl, D

    2013-01-01

    BACKGROUND The prevalence and detrimental health effects of intimate partner violence have resulted in international discussions and recommendations that health care professionals should screen women for intimate partner violence during general and antenatal health care visits. Due to the lack of discussion on routine or case-based inquiry for intimate partner violence during antenatal care in Germany, this study seeks to explore its acceptability among pregnant German women. METHODS A m...

  10. A population based case-control study of agricultural injuries in children.

    OpenAIRE

    Stueland, D. T.; Lee, B.C.; Nordstrom, D L; Layde, P M; Wittman, L. M.

    1996-01-01

    OBJECTIVES: To identify preventable risk factors related to agricultural injuries occurring to children on family farms. SETTING: A geographically defined central region of Wisconsin, USA with nearly 1800 family dairy farms. METHODS: A two year, population based incidence study of occupational injuries among farm residents was conducted. For cases, trained staff abstracted information on the nature, severity, and treatment of the injury from the patient's medical record. Staff also administer...

  11. Service Quality of Online Shopping Platforms: A Case-Based Empirical and Analytical Study

    OpenAIRE

    Bin Shen; Shuk-Ching Liu; Bowood Kwok; Tsan-Ming Choi; Pui-Sze Chow

    2013-01-01

    Customer service is crucially important for online shopping platforms (OSPs) such as eBay and Taobao. Based on the well-established service quality instruments and the scenario of the specific case on Taobao, this paper focuses on exploring the service quality of an OSP with an aim of revealing customer perceptions of the service quality associated with the provided functions and investigating their impacts on customer loyalty. By an empirical study, this paper finds that the “fulfillment and...

  12. Case study: use of problem-based learning to develop students' technical and professional skills

    Science.gov (United States)

    Warnock, James N.; Mohammadi-Aragh, M. Jean

    2016-03-01

    Problem-based learning (PBL) is a pedagogy that has attracted attention for many biomedical engineering curricula. The aim of the current study was to address the research question, 'Does PBL enable students to develop desirable professional engineering skills?' The desirable skills identified were communication, teamwork, problem solving and self-directed learning. Forty-seven students enrolled in a biomedical materials course participated in the case study. Students worked in teams to complete a series of problems throughout the semester. The results showed that students made significant improvements in their problem-solving skills, written communication and self-directed learning. Students also demonstrated an ability to work in teams and communicate orally. In conclusion, this case study provides empirical evidence of the efficacy of PBL on student learning. We discuss findings from our study and provide observations of student performance and perceptions that could be useful for faculty and researchers interested in PBL for biomedical engineering education.

  13. How substance-based ontologies for gravity can be productive: A case study

    Science.gov (United States)

    Gupta, Ayush; Elby, Andrew; Conlin, Luke D.

    2014-06-01

    Many science education researchers have argued that learners' commitment to a substance (matter-based) ontology impedes the learning of scientific concepts that scientists typically conceptualize as processes or interactions, such as force, electric current, and heat. By this account, students' tendency to classify these entities as substances or properties of substances leads to robust misconceptions, and instruction should steer novices away from substance-based reasoning. We argue that substance-based reasoning can contribute to the learning and understanding of these very same physics concepts. Our case study focuses on a group of elementary school science teachers in our professional development program. Starting from substance-based metaphors for gravity, the teachers build a sophisticated explanation for why objects of different masses fall with the same acceleration. We argue that, for conceptual, epistemological, and affective reasons, instructional interventions should focus on tapping these productive substance-based resources when they arise rather than attempting to suppress them.

  14. Bra wearing not associated with breast cancer risk: a population based case-control study

    OpenAIRE

    Chen, Lu; Malone, Kathleen E.; Li, Christopher I.

    2014-01-01

    Despite the widespread use of bras among U.S. women and concerns in the lay media that bra wearing may increase breast cancer risk, there is a scarcity of credible scientific studies addressing this issue. The goal of the study was to evaluate the relationship between various bra wearing habits and breast cancer risk among postmenopausal women. We conducted a population-based case-control study of breast cancer in the Seattle-Puget Sound metropolitan area that compared 454 invasive ductal car...

  15. Suicide by people in a community justice pathway: population-based nested case-control study.

    Science.gov (United States)

    King, Carlene; Senior, Jane; Webb, Roger T; Millar, Tim; Piper, Mary; Pearsall, Alison; Humber, Naomi; Appleby, Louis; Shaw, Jenny

    2015-08-01

    The elevated risk of suicide in prison and after release is a well-recognised and serious problem. Despite this, evidence concerning community-based offenders' suicide risk is sparse. We conducted a population-based nested case-control study of all people in a community justice pathway in England and Wales. Our data show 13% of general population suicides were in community justice pathways before death. Suicide risks were highest among individuals receiving police cautions, and those having recent, or impending prosecution for sexual offences. Findings have implications for the training and practice of clinicians identifying and assessing suicidality, and offering support to those at elevated risk. PMID:26159602

  16. Association between Gastroesophageal Reflux Disease and Appendicitis: A Population-Based Case-Control Study

    Science.gov (United States)

    Kao, Li-Ting; Tsai, Ming-Chieh; Lin, Herng-Ching; Lee, Cha-Ze

    2016-01-01

    Appendicitis and gastroesophageal reflux disease (GERD) are both prevalent diseases and might share similar pathological mechanisms. The aim of this study was to investigate the association between GERD and appendicitis using a large population-based dataset. This study used administrative claims data from the Taiwan Longitudinal Health Insurance Database 2005. We identified 7113 patients with appendicitis as cases, and 28452 matched patients without appendicitis as controls. This study revealed that GERD was found in 359 (5.05%) cases and 728 (2.56%) controls (p appendicitis were 1.96 (95% CI: 1.56~2.47), 2.36 (95% CI: 1.94~2.88), and 1.71 (95% CI: 1.31~2.22) than controls, respectively. We concluded that patients with appendicitis had higher odds of prior GERD than those without appendicitis regardless of age group. PMID:26932391

  17. How substance-based ontologies for gravity can be productive: A case study

    CERN Document Server

    Gupta, Ayush; Conlin, Luke D

    2013-01-01

    Many science education researchers have argued that learners' commitment to a substance (matter-based) ontology impedes the learning of scientific concepts that scientists typically conceptualize as processes or interactions, such as such as force, electric current, and heat. By this account, students' tendency to classify these entities as substances or properties of substances leads to robust misconceptions, and instruction should steer novices away from substance-based reasoning. We argue that substance-based reasoning, when it supports learners' sense-making, can form the seeds for sophisticated understanding of these very same physics concepts. We present a case study of a group of elementary school science teachers in our professional development program. The teachers build a sophisticated explanation for why objects of different masses have the same acceleration due to gravity, starting from substance-based metaphors for gravity. We argue that, for conceptual, epistemological, and affective reasons, in...

  18. Web-based Peer Assessment: A Case Study with Civil Engineering Students

    Directory of Open Access Journals (Sweden)

    Gonçalo Cruz

    2013-02-01

    Full Text Available Peer-assessed online collaborative writing is of growing importance for higher education. Based on the quantitative and qualitative analysis of collected data, this work presents the results of a case study in a graduate civil engineering course at the University of Trás-os-Montes e Alto Douro, Vila Real, Portugal. After an overall presentation of the learning activity, it examines students’ attitudes towards web-based peer assessment and identifies which factors are related to students’ use and appreciation of feedback. In addition, an analysis of the type of feedback is presented in an attempt to evaluate students’  written communication skills. The results of this study provide indications on how to improve the design and implementation of future web-based peer assessment tasks and raise questions on the effectiveness of peer/teacher grading in the use of feedback.

  19. Evaluating Pillar Industry's Transformation Capability: A Case Study of Two Chinese Steel-Based Cities.

    Directory of Open Access Journals (Sweden)

    Zhidong Li

    Full Text Available Many steel-based cities in China were established between the 1950s and 1960s. After more than half a century of development and boom, these cities are starting to decline and industrial transformation is urgently needed. This paper focuses on evaluating the transformation capability of resource-based cities building an evaluation model. Using Text Mining and the Document Explorer technique as a way of extracting text features, the 200 most frequently used words are derived from 100 publications related to steel- and other resource-based cities. The Expert Evaluation Method (EEM and Analytic Hierarchy Process (AHP techniques are then applied to select 53 indicators, determine their weights and establish an index system for evaluating the transformation capability of the pillar industry of China's steel-based cities. Using real data and expert reviews, the improved Fuzzy Relation Matrix (FRM method is applied to two case studies in China, namely Panzhihua and Daye, and the evaluation model is developed using Fuzzy Comprehensive Evaluation (FCE. The cities' abilities to carry out industrial transformation are evaluated with concerns expressed for the case of Daye. The findings have policy implications for the potential and required industrial transformation in the two selected cities and other resource-based towns.

  20. Case-based reasoning

    CERN Document Server

    Kolodner, Janet

    1993-01-01

    Case-based reasoning is one of the fastest growing areas in the field of knowledge-based systems and this book, authored by a leader in the field, is the first comprehensive text on the subject. Case-based reasoning systems are systems that store information about situations in their memory. As new problems arise, similar situations are searched out to help solve these problems. Problems are understood and inferences are made by finding the closest cases in memory, comparing and contrasting the problem with those cases, making inferences based on those comparisons, and asking questions whe

  1. Communicating for Climate Change Adaptation: Lessons from a Case Study with Nature-Based Tour Operators

    Science.gov (United States)

    Timm, K.; Sparrow, E. B.; Pettit, E. C.; Trainor, S. F.; Taylor, K.

    2014-12-01

    Increasing temperatures are projected to have a positive effect on the length of Alaska's tourism season, but the natural attractions that tourism relies on, such as glaciers, wildlife, fish, or other natural resources, may change. In order to continue to derive benefits from these resources, nature-based tour operators may have to adapt to these changes, and communication is an essential, but poorly understood, component of the climate change adaptation process. The goal of this study was to determine how to provide useful climate change information to nature-based tour operators by answering the following questions: 1. What environmental changes do nature-based tour operators perceive? 2. How are nature-based tour operators responding to climate and environmental change? 3. What climate change information do nature-based tour operators need? To answer these questions, twenty-four nature-based tour operators representing 20 different small and medium sized businesses in Juneau, Alaska were interviewed. The results show that many of Juneau's nature-based tour operators are observing, responding to, and in some cases, actively planning for further changes in the environment. The types of responses tended to vary depending on the participants' certainty in climate change and the perceived risks to their organization. Using these two factors, this study proposes a framework to classify climate change responses for the purpose of generating meaningful information and communication processes that promote adaptation and build adaptive capacity. During the course of the study, several other valuable lessons were learned about communicating about adaptation. The results of this study demonstrate that science communication research has an important place in the practice of promoting and fostering climate change adaptation. While the focus of this study was tour operators, the lessons learned may be valuable to other organizations striving to engage unique groups in climate

  2. Image enhancement based on in vivo hyperspectral gastroscopic images: a case study.

    Science.gov (United States)

    Gu, Xiaozhou; Han, Zhimin; Yao, Liqing; Zhong, Yunshi; Shi, Qiang; Fu, Ye; Liu, Changsheng; Wang, Xiguang; Xie, Tianyu

    2016-10-01

    Hyperspectral imaging (HSI) has been recognized as a powerful tool for noninvasive disease detection in the gastrointestinal field. However, most of the studies on HSI in this field have involved ex vivo biopsies or resected tissues. We proposed an image enhancement method based on in vivo hyperspectral gastroscopic images. First, we developed a flexible gastroscopy system capable of obtaining in vivo hyperspectral images of different types of stomach disease mucosa. Then, depending on a specific object, an appropriate band selection algorithm based on dependence of information was employed to determine a subset of spectral bands that would yield useful spatial information. Finally, these bands were assigned to be the color components of an enhanced image of the object. A gastric ulcer case study demonstrated that our method yields higher color tone contrast, which enhanced the displays of the gastric ulcer regions, and that it will be valuable in clinical applications. PMID:27206742

  3. UNDERSTANDING THE APPLICABILITY OF LINEAR & NON-LINEAR MODELS USING A CASE-BASED STUDY

    OpenAIRE

    Gaurav Singh Thakur; Anubhav Gupta; Ankur Bhardwaj; Biju R Mohan

    2014-01-01

    This paper uses a case based study – “product sales estimation” on real-time data to help us understand the applicability of linear and non-linear models in machine learning and data mining. A systematic approach has been used here to address the given problem statement of sales estimation for a particular set of products in multiple categories by applying both linear and non-linear machine learning techniques on a data set of selected features from the original data set. Feature ...

  4. The Special Place Project: Efficacy of a Place-Based Case Study Approach for Teaching Geoscience

    Science.gov (United States)

    Moosavi, Sadredin

    2014-05-01

    Achieving geoscience literacy of the general population has become increasingly important world wide as ever more connected and growing societies depend more and more on our planet's limited natural resource base. Building citizen understanding of their dependence on the local environment, and the geologic processes which created and continue to change it, has become a great challenge to educators at all levels of the education system. The Special Place Project described in this presentation explores use of a place-based case study approach combining instruction in geoscience content with development of observation, reasoning, writing and presentation skills. The approach allows students to select the locations for their individual case studies affording development of personal connections between the learner and his environment. The approach gives instructors at many grade levels the ability to develop core pedagogical content and skills while exploring the unique geologic environments relevant to the local population including such critical issues as land use, resource depletion, energy, climate change and the future of communities in a changing world. The geologic reasons for the location of communities and key events in their histories can be incorporated into the students' case studies as appropriate. The project is unique in placing all course instruction in the context of the quest to explore and gain understanding of the student's chosen location by using the inherently more generalized course content required by the curriculum. By modeling how scientists approach their research questions, this pedagogical technique not only integrates knowledge and skills from across the curriculum, it captures the excitement of scientific thinking on real world questions directly relevant to students' lives, increasing student engagement and depth of learning as demonstrated in the case study reports crafted by the students and exam results. Student learning of topics

  5. Risk of miscarriage for pregnant users of pivmecillinam: a population-based case-control study.

    Science.gov (United States)

    Nørgaard, Mette; Skriver, Mette Vinther; Sørensen, Henrik Toft; Schønheyder, Henrik Carl; Pedersen, Lars

    2008-04-01

    Few data exist on the risk of miscarriage after exposure to pivmecillinam. We therefore conducted a population-based case-control study in a Danish county with 0.5 million inhabitants during the period 1997-2002. We included 1,599 women with a miscarriage recorded in the Hospital Discharge Registry and selected 10 controls per case among primiparous women who had a live birth during the study period. Controls were selected from the Danish Medical Birth Registry. We obtained data on use of pivmecillinam and sulfamethizole from a prescription database. Five cases (0.30%) and 24 controls (0.15%) were exposed to pivmecillinam in the last week before the miscarriage/index date. After adjustment for maternal age, use of antidiabetics or antiepileptics, the odds ratio for miscarriages among users of pivmecillinam compared with non-users was 2.03 (95% confidence interval: 0.77-5.33) and the corresponding odds ratio for use of sulfamethizole was 1.53 (95% confidence interval: 0.76-3.09). Exposure within 2 to 12 weeks before the miscarriage was not associated with an increased risk. We concluded that use of pivmecillinam was associated with an increased risk of miscarriage, but the risk was not significantly (p=0.64) different from the risk associated with use of sulfamethizole. PMID:18397462

  6. Mass screening-based case-control study of diet and prostate cancer in Changchun, China

    Institute of Scientific and Technical Information of China (English)

    Xiao-Meng Li; Jiang Li; Ichiro Tsuji; Naoki Nakaya; Yoshikazu Nishino; Xue-Jian Zhao

    2008-01-01

    Aim: To investigate possible correlation factors for prostate cancer by a population-based case-control study in China. Methods: We carded out a mass screening of prostate cancer in Changchun, China, using a prostate-specific antigen assisted by Japan International Cooperation Agency. From June 1998 to December 2000, 3 940 men over 50 years old were screened. Of these, 29 men were diagnosed with prostate cancer. We selected 28 cases and matched them with controls of low prostate-specific antigen value (< 4.1 ng/mL) by 1:10 according to age and place of employment. A case-control study of diet and prostate cancer was then carded out. Results: After adjustment for education, body mass index (BMI), smoking, alcohol consumption, marriage and diet, intake of soybean product was discovered to be inversely related to prostate cancer. Men who consumed soybean product more than twice per week on different days had a multivariate odds ratio (OR) of 0.38 (95% confidence interval [CI], 0.13-1.12). In addition, men who consumed soybean products more than once per day had a multivariate OR of 0.29 (95% CI, 0.11-0.79) compared with men who consumed soybean products less than once per week. The P for trend was 0.02, which showed significant difference. There was no significant difference in P trend for any dairy food. Even when we matched the cases and controls by other criteria, we found that soybean food was the only preventive factor associated with prostate cancer. Conclusion: Our study suggests that consumption of soybeans, one of the most popular foods in Asia, would decrease the risk of prostate cancer. (Asian J Androl 2008 Jul; 10: 551-560)

  7. A climate-based spatiotemporal prediction for dengue fever epidemics: a case study in southern Taiwan

    Science.gov (United States)

    Yu, H.-L.; Yang, S.-J.; Lin, Y.-C.

    2012-04-01

    Dengue Fever (DF) has been identified by the World Health organization (WHO) as one of the most serious vector-borne infectious diseases in tropical and sub-tropical areas. DF has been one of the most important epidemics in Taiwan which occur annually especially in southern Taiwan during summer and autumn. Most DF studies have focused mainly on temporal DF patterns and its close association with climatic covariates, whereas few studies have investigated the spatial DF patterns (spatial dependence and clustering) and composite space-time effects of the DF epidemics. The present study proposes a spatio-temporal DF prediction approach based on stochastic Bayesian Maximum Entropy (BME) analysis. Core and site-specific knowledge bases are considered, including climate and health datasets under conditions of uncertainty, space-time dependence functions, and a Poisson regression model of climatic variables contributing to DF occurrences in southern Taiwan during 2007, when the highest number of DF cases was recorded in the history of Taiwan epidemics (over 2000). The obtained results show that the DF outbreaks in the study area are highly influenced by climatic conditions. Furthermore, the analysis can provide the required "one-week-ahead" outbreak warnings based on spatio-temporal predictions of DF distributions. Therefore, the proposed analysis can provide the Taiwan Disease Control Agency with a valuable tool to timely identify, control, and even efficiently prevent DF spreading across space-time.

  8. Integrated vibration-based maintenance: an approach for continuous reduction in LCC. A case study

    Energy Technology Data Exchange (ETDEWEB)

    Najjar, B. [ER Konsult Utveckling AB, Vaexjoe (Sweden)

    1998-12-31

    The biggest thread in achieving and maintaining high equipment effectiveness can be stated as: whether the improved manufacturing processes capable of producing quality products at a competitive cost. The effect of a new vibration-based maintenance concept, called Total Quality Maintenance (TQMain), is introduced. It aims to make intensive use of the real-time data acquisition and analysis to detect causes behind product quality deviation and failures in machinery, and following defect development at an early stage to increase machine mean effective life and improve company`s economics. The effect of TQMain on LCC of machinery and company`s economics is discussed. A case study to reveal savings in maintenance cost when a vibration-based policy involved, is presented. Using TQMain, company`s economics can be improved effectively through continuous improvement of the technical and economic effectiveness of production processes. (orig.) 14 refs.

  9. Economics of pyrolysis-based energy production and biochar utilization: A case study in Taiwan

    International Nuclear Information System (INIS)

    Pyrolysis is an alternative form of renewable energy production and a potential source of greenhouse gas emissions mitigation. This study examines how poplar-based biochar can be applied in Taiwan for electricity generation and for soil improvement and to what extent it brings economic and environmental benefits. It is a preliminary study and focuses on the balances of different economic and environmental items. This paper reports on a case study examination of the economic and greenhouse gas implications of pyrolysis plus biochar utilization. The case study involves using poplar grown on set-aside land in Taiwan with the biochar applied to rice fields. We examine both fast and slow forms of pyrolysis and find how the profitability varies under different price structures. The results show that fast pyrolysis is more profitable than slow pyrolysis under current electricity price, GHG price and crop yield as the slow pyrolysis generates relatively less electricity but lower value product—biochar. We also find that fast pyrolysis and slow pyrolysis offset about 1.4 t and 1.57 t of CO2 equivalent per ton of raw material, respectively. - Highlights: • Profitability varies due to sales revenue from electricity generation. • Neither fast pyrolysis nor slow pyrolysis is profitable under current electricity price. • Both systems offset about 1.4 t to 1.57 t of CO2 equivalent per ton of raw material

  10. When to be skeptical of negative studies: pitfalls in evaluating occupational risks using population-based case-control studies.

    Science.gov (United States)

    Hu, S W; Hertz-Picciotto, I; Siemiatycki, J

    1999-01-01

    This study investigated arsenic and lung cancer incidence in a community setting in the Montreal area. Job histories and sociodemographic factors were collected by interview from 857 lung cancer cases, 533 general population controls, and 1,360 controls with other cancers. Chemist-hygienists assessed each subject's life-time occupational exposure to 294 substances. Logistic regressions yielded arsenic/lung cancer odds ratios of 1.1 (95% confidence interval = 0.60, 1.7) based on cancer controls, and 0.82 (95% confidence interval = 0.41, 1.6) based on population controls. Risk did not rise with increasing level or probability of exposure. Worksite studies consistently show lung carcinogenicity from arsenic. Since confounding from other chemicals was well controlled, the most likely explanation is substantially lower exposures than in previous studies. The lack of association in this study demonstrates the need for caution in interpreting negative findings from population-based case-control studies, particularly when exposures are low or rare, as well as the difficulty in generating hypotheses from such studies. PMID:10349223

  11. Critical evaluation of financial supporting schemes for wind-based projects: Case study Greece

    International Nuclear Information System (INIS)

    After a long stagnating period during the second half of the 1990s, the market of wind energy in Greece was described by remarkable but unstable growth rates that resulted in the operation of 1 GW of wind power by the end of 2009. Still though, penetration of wind energy is not the one anticipated. On the other hand, national targets regarding the Renewable Energy Sources' (RES) contribution and existence of excellent wind potential areas across Greece challenge new wind energy investments. Acknowledging the unsteady development rates of wind power in Greece, efficiency of the State support mechanisms is currently investigated. Based on an analytical evaluation model, the investigation undertaken is extended to provide a detailed cost-benefit analysis of several wind energy case studies, including mainland and island applications as well as comparison with both conventional power stations and photovoltaic plants. For this purpose, the financial support provided by the State is directly compared with benefits accruing from the operation of wind parks, considering also the avoidance of social costs deriving from thermal power stations. Based on the results obtained, the beneficial characteristics of wind energy applications for the Greek society are clearly demonstrated, especially in the case of non-interconnected island grids. - Research highlights: → Since the mid-1990s, growth of wind power capacity in Greece has been unstable. → As a result, integration of wind energy is not the one anticipated. → Considering the situation, efficiency of State support mechanisms is evaluated. → An analytical cost-benefit model is developed and applied to various case studies. → Benefits from wind energy, especially in island regions, are designated.

  12. Incretin-Based Therapy and Risk of Acute Pancreatitis: A Nationwide Population-Based Case-Control Study

    DEFF Research Database (Denmark)

    Thomsen, Reimar Wernich; Pedersen, Lars; Møller, Niels;

    2015-01-01

    OBJECTIVE: To investigate whether the use of incretin-based drugs (GLP-1 receptor agonists and dipeptidyl peptidase 4 [DPP4] inhibitors) is associated with acute pancreatitis. RESEARCH DESIGN AND METHODS: The study was a nationwide population-based case-control study using medical databases in...... Denmark. Participants were 12,868 patients with a first-time hospitalization for acute pancreatitis between 2005 and 2012 and a population of 128,680 matched control subjects. The main outcome measure was the odds ratio (OR) for acute pancreatitis associated with different antihyperglycemic drugs. We...... adjusted for history of gallstones, alcoholism, obesity, and other pancreatitis-associated comorbidities and medications. RESULTS: A total of 89 pancreatitis patients (0.69%) and 684 control subjects (0.53%) were ever users of incretins. The crude OR for acute pancreatitis among incretin users was 1.36 (95...

  13. Case Study: Writing a Journal Case Study

    Science.gov (United States)

    Prud'homme-Genereux, Annie

    2016-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue describes incorporating a journal article into the classroom by first converting it into a case study.

  14. Agent-based modelling as scientific method: a case study analysing primate social behaviour.

    Science.gov (United States)

    Bryson, Joanna J; Ando, Yasushi; Lehmann, Hagen

    2007-09-29

    A scientific methodology in general should provide two things: first, a means of explanation and, second, a mechanism for improving that explanation. Agent-based modelling (ABM) is a method that facilitates exploring the collective effects of individual action selection. The explanatory force of the model is the extent to which an observed meta-level phenomenon can be accounted for by the behaviour of its micro-level actors. This article demonstrates that this methodology can be applied to the biological sciences; agent-based models, like any other scientific hypotheses, can be tested, critiqued, generalized or specified. We review the state of the art for ABM as a methodology for biology and then present a case study based on the most widely published agent-based model in the biological sciences: Hemelrijk's DomWorld, a model of primate social behaviour. Our analysis shows some significant discrepancies between this model and the behaviour of the macaques, the genus used for our analysis. We also demonstrate that the model is not fragile: its other results are still valid and can be extended to compensate for these problems. This robustness is a standard advantage of experiment-based artificial intelligence modelling techniques over analytic modelling. PMID:17434852

  15. Cloud-Based Environmental Impact Assessment Expert System – A Case Study of Fiji

    Directory of Open Access Journals (Sweden)

    Sam Goundar

    2013-11-01

    Full Text Available Environmental impact assessments [EIA] involve identifying, measuring, and assessing impacts. This complex process deals with considerable amount of information and requires processing and analysis of quantitative data, qualitative information as well as expert human judgements. Often, available information is incomplete, subjective, and inconsistent. This challenge of collecting, processing, analyzing, and reporting EIA information can be met by computer systems. A Cloud-based Environmental Impact Assessment [EIA] system is proposed in this paper to overcome the many challenges faced by practitioners. Fiji’s EIA process is used as a case study. The steps involved in the process are automated as a sequence of computer executable programs with Expert System. Based on the information provided about projects, the EIA system is expected to compute environmental impacts and produce Environment Impact Statements. With the system, a user enters information about the environmental settings in which the development project is expected to take place as well as the proposed development project activities. Based on the input, an expert system with an inference engine uses rules to check the knowledge base and report on possible impacts and mitigation actions. The knowledge base is connected to databases on domain experts, GIS and simulation models.

  16. Level of neurotoxic metals in amyotrophic lateral sclerosis: A population-based case-control study.

    Science.gov (United States)

    Bocca, Beatrice; Forte, Giovanni; Oggiano, Riccardo; Clemente, Simonetta; Asara, Yolande; Peruzzu, Angela; Farace, Cristiano; Pala, Salvatore; Fois, Alessandro Giuseppe; Pirina, Pietro; Madeddu, Roberto

    2015-12-15

    The association between exposure to toxic metals and amyotrophic lateral sclerosis (ALS) was explored in a population-based case-control study in the Sardinia island (Italy), a region characterized by elevated rates of ALS cases. In 34 patients with ALS (mean age, 62 ± 10 years) and 30 controls (mean age, 65 ± 11 years), Al, Cd, Hg, Mn and Pb were determined in blood, hair and urine by sector field inductively coupled mass spectrometry. Results indicated that, in blood, concentrations of Al (p=0.045) and Pb were higher (p=0.026) in ALS patients than in control subjects. In hair, a depletion of Al (p=0.006) and Mn (p=0.032) concentrations in ALS subjects respect to controls was found. In urine, no significant differences between cases and controls were observed. Thus, some metals seemed to be associated with ALS degeneration, but a definitive conclusion is still far considering the multiple risk factors (genetic mutations, environmental toxicants and stressors) involved in the disease. Finally, the interpretation that deregulated metal concentrations can be a consequence of the degenerative process, rather than a cause, is also valid. PMID:26671079

  17. Association between schizophrenia and urinary calculi: a population-based case-control study.

    Directory of Open Access Journals (Sweden)

    Shih-Ping Liu

    Full Text Available BACKGROUND: People with schizophrenia have been demonstrated to have higher overall morbidity and all-cause mortality rates from general medical conditions. However, little attention has been given to the urinary system of people with schizophrenia. As no direct evidence has been reported demonstrating a link between schizophrenia and urinary calculi, this study utilized a population-based case-control study design to investigate the possibility of an association between schizophrenia and the occurrence of urinary calculi. METHOD: This study used data from the Taiwan Longitudinal Health Insurance Database. Cases consisted of 53,965 urinary calculi patients newly diagnosed between 2002 and 2008. In total, 269,825 controls were randomly selected and matched with the cases in terms of age and sex. Each person was traced to discern whether he had previously received a diagnosis of schizophrenia. Conditional logistic regression models were performed for the analysis. RESULTS: A total of 3,119 (1.0% subjects had been diagnosed with schizophrenia prior to the index date. This included 0.7% of the patients with urinary calculi, and 1.0% of the controls. A prior diagnosis of schizophrenia was independently associated with a 30% decrease (95% CI = 0.62-0.76 in the occurrence of urinary calculi. The reduction was even more remarkable in males (38%, 95% CI = 0.55-0.71 and in elder individuals independent of gender (48% in those aged >69, 95% CI = 0.36-0.77. CONCLUSION: Our findings suggest that there is an inverse association between schizophrenia and urinary calculi. Future studies are needed to elucidate the mechanisms by which schizophrenia negatively associates with urinary calculi.

  18. Teaching Introductory Oceanography through Case Studies: Project based approach for general education students

    Science.gov (United States)

    Farnsworth, K. L.; House, M.; Hovan, S. A.

    2013-12-01

    A recent workshop sponsored by SERC-On the Cutting Edge brought together science educators from a range of schools across the country to discuss new approaches in teaching oceanography. In discussing student interest in our classes, we were struck by the fact that students are drawn to emotional or controversial topics such as whale hunting and tsunami hazard and that these kinds of topics are a great vehicle for introducing more complex concepts such as wave propagation, ocean upwelling and marine chemistry. Thus, we have developed an approach to introductory oceanography that presents students with real-world issues in the ocean sciences and requires them to explore the science behind them in order to improve overall ocean science literacy among non-majors and majors at 2 and 4 year colleges. We have designed a project-based curriculum built around topics that include, but are not limited to: tsunami hazard, whale migration, ocean fertilization, ocean territorial claims, rapid climate change, the pacific trash patch, overfishing, and ocean acidification. Each case study or project consists of three weeks of class time and is structured around three elements: 1) a media analysis; 2) the role of ocean science in addressing the issue; 3) human impact/response. Content resources range from textbook readings, popular or current print news, documentary film and television, and data available on the world wide web from a range of sources. We employ a variety of formative assessments for each case study in order to monitor student access and understanding of content and include a significant component of in-class student discussion and brainstorming guided by faculty input to develop the case study. Each study culminates in summative assessments ranging from exams to student posters to presentations, depending on the class size and environment. We envision this approach for a range of classroom environments including large group face-to-face instruction as well as hybrid

  19. Challenges in Post Merger Integration: an analysis based on a case study from CEE

    OpenAIRE

    Vodák, Martin

    2011-01-01

    The thesis is covering an analysis of a concrete acquisition case from CEE. Based on the review of theory a conceptual framework was created and then applied to the acquisition case in order to analyze the process of post-merger integration. As a result, recommendations were created for similar future transactions.

  20. An analysis of the perceived benefits of a case study-based competition in financial management / Rona van Hoepen

    OpenAIRE

    Van Hoepen, Rona

    2015-01-01

    Students from 24 participating regions take part in teams of four in the CIMA (Chartered Institute of Management Accountants) GBC (Global Business Challenge) annually. The GBC is in the form of a business competition which is based on a case study of a real company. The participants receive the case study on which they should submit a written report. Teams are shortlisted based on the reports, and the shortlisted teams have to prepare a presentation to a panel of judges. This study explore...

  1. Air Pollution and the Risk of Cardiac Defects: A Population-Based Case-Control Study.

    Science.gov (United States)

    Hwang, Bing-Fang; Lee, Yungling Leo; Jaakkola, Jouni J K

    2015-11-01

    Previous epidemiologic studies have assessed the role of the exposure to ambient air pollution in the development of cardiac birth defects, but they have provided somewhat inconsistent results. To assess the associations between exposure to ambient air pollutants and the risk of cardiac defects, a population-based case-control study was conducted using 1087 cases of cardiac defects and a random sample of 10,870 controls from 1,533,748 Taiwanese newborns in 2001 to 2007.Logistic regression was performed to calculate odds ratios for 10 ppb increases in O3 and 10 μg/m increases in PM10. In addition, we compared the risk of cardiac defects in 4 categories-high exposure (>75th percentile); medium exposure (75th to 50th percentile); low exposure (patent ductus arteriosus (PDA) were associated with 10 ppb increases in O3 exposure during the first 3 gestational months among term and preterm babies. In comparison between high PM10 exposure and reference category, there were statistically significant elevations in the effect estimates of ASD for all and terms births. In addition, there was a negative or weak association between SO2, NO2, CO, and cardiac defects.The study proved that exposure to outdoor air O3 and PM10 during the first trimester of gestation may increase the risk of VSD, ASD, and PDA. PMID:26554783

  2. Breast cancer risk associated with different HRT formulations: a register-based case-control study

    OpenAIRE

    Thai Do; Möhner Sabine; Heinemann Lothar AJ; Dinger Juergen C; Assmann Anita

    2006-01-01

    Abstract Background Previous epidemiological studies have inconsistently shown a modestly increased breast cancer risk associated with hormone replacement therapy (HRT). Limited information is available about different formulations – particularly concerning different progestins. Methods A case-control study was performed within Germany in collaboration with regional cancer registries and tumor centers. Up to 5 controls were matched breast cancer cases. Conditional logistic regression analysis...

  3. Tumor-based case-control studies of infection and cancer: muddling the when and where of molecular epidemiology.

    Science.gov (United States)

    Engels, Eric A; Wacholder, Sholom; Katki, Hormuzd A; Chaturvedi, Anil K

    2014-10-01

    We describe the "tumor-based case-control" study as a type of epidemiologic study used to evaluate associations between infectious agents and cancer. These studies assess exposure using diseased tissues from affected individuals (i.e., evaluating tumor tissue for cancer cases), but they must utilize nondiseased tissues to assess control subjects, who do not have the disease of interest. This approach can lead to exposure misclassification in two ways. First, concerning the "when" of exposure assessment, retrospective assessment of tissues may not accurately measure exposure at the key earlier time point (i.e., during the etiologic window). Second, concerning the "where" of exposure assessment, use of different tissues in cases and controls can have different accuracy for detecting the exposure (i.e., differential exposure misclassification). We present an example concerning the association of human papillomavirus with various cancers, where tumor-based case-control studies likely overestimate risk associated with infection. In another example, we illustrate how tumor-based case-control studies of Helicobacter pylori and gastric cancer underestimate risk. Tumor-based case-control studies can demonstrate infection within tumor cells, providing qualitative information about disease etiology. However, measures of association calculated in tumor-based case-control studies are prone to over- or underestimating the relationship between infections and subsequent cancer risk. PMID:25063520

  4. Background radiation and childhood leukemia: A nationwide register-based case-control study.

    Science.gov (United States)

    Nikkilä, Atte; Erme, Sini; Arvela, Hannu; Holmgren, Olli; Raitanen, Jani; Lohi, Olli; Auvinen, Anssi

    2016-11-01

    High doses of ionizing radiation are an established cause of childhood leukemia. However, substantial uncertainty remains about the effect of low doses of radiation, including background radiation and potential differences between genetic subgroups of leukemia have rarely been explored. We investigated the effect of the background gamma radiation on childhood leukemia using a nationwide register-based case-control study. For each of the 1,093 cases, three age- and gender matched controls were selected (N = 3,279). Conditional logistic regression analyses were adjusted for confounding by Down syndrome, birth weight (large for gestational age), and maternal smoking. Complete residential histories and previously collected survey data of the background gamma radiation in Finland were used to assess the exposure of the study subjects to indoor and outdoor gamma radiation. Overall, background gamma radiation showed a non-significant association with the OR of childhood leukemia (OR 1.01, 95% CI 0.97, 1.05 for 10 nSv/h increase in average equivalent dose rate to red bone marrow). In subgroup analyses, age group 2-childhood leukemia, particularly at age 2-<7 years. Our findings suggest a larger effect of radiation on leukemia with high hyperpdiploidy than other subgroups, but this result requires further confirmation. PMID:27405274

  5. Asthma and Risk of Prostate Cancer: A Population-Based Case-Cohort Study in Taiwan.

    Science.gov (United States)

    Su, Yu-Li; Chou, Ching-Lan; Rau, Kun-Ming; Lee, Charles Tzu-Chi

    2015-09-01

    Several epidemiologic studies in Western countries have examined the association between asthma and prostate cancer risk, but the results have been inconclusive. We investigated this association in a large, nationwide, population-based case-cohort study. Using the Taiwan National Health Insurance Research Database from 1997 to 2008, we collected data from 12,372 men, including 4124 with asthma and 8248 age-, residence-, and insurance premium-matched control subjects, who were never diagnosed with asthma. Competing risk-adjusted Cox proportional hazards regression was used to calculate the hazard ratios (HRs) and 95% confidence interval (CI) for determining the association between prostate cancer and asthma. During a mean follow-up of 5.05 years (standard deviation, 2.10), there were 74 cases of prostate cancer. The incidence of prostate cancer was 163.0/100,000 person-years (95% CI: 113.0-228.0) in the asthma patients. Asthma was significantly associated with prostate cancer (HR: 2.36; 95% CI: 1.22-4.57; P = 0.011) after adjusting for age, residential area, insurance premium, hypertriglyceridemia, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, duration of hospitalization, and mortality. In the subgroup analysis, independent risk factors for prostate cancer among men with asthma were age (HR: 1.09; 95% CI: 1.05-1.21; P risk of prostate cancer. PMID:26356691

  6. Case Based Reasoning: Case Representation Methodologies

    Directory of Open Access Journals (Sweden)

    Shaker H. El-Sappagh

    2015-11-01

    Full Text Available Case Based Reasoning (CBR is an important technique in artificial intelligence, which has been applied to various kinds of problems in a wide range of domains. Selecting case representation formalism is critical for the proper operation of the overall CBR system. In this paper, we survey and evaluate all of the existing case representation methodologies. Moreover, the case retrieval and future challenges for effective CBR are explained. Case representation methods are grouped in to knowledge-intensive approaches and traditional approaches. The first group overweight the second one. The first methods depend on ontology and enhance all CBR processes including case representation, retrieval, storage, and adaptation. By using a proposed set of qualitative metrics, the existing methods based on ontology for case representation are studied and evaluated in details. All these systems have limitations. No approach exceeds 53% of the specified metrics. The results of the survey explain the current limitations of CBR systems. It shows that ontology usage in case representation needs improvements to achieve semantic representation and semantic retrieval in CBR system.

  7. Human-centered modeling in human reliability analysis: some trends based on case studies

    International Nuclear Information System (INIS)

    As an informal working group of researchers from France, Germany and The Netherlands created in 1993, the EARTH association is investigating significant subjects in the field of human reliability analysis (HRA). Our initial review of cases from nuclear operating experience showed that decision-based unrequired actions (DUA) contribute to risk significantly on the one hand. On the other hand, our evaluation of current HRA methods showed that these methods do not cover such actions adequately. Especially, practice-oriented guidelines for their predictive identification are lacking. We assumed that a basic cause for such difficulties was that these methods actually use a limited representation of the stimulus-organism-response (SOR) paradigm. We proposed a human-centered model, which better highlights the active role of the operators and the importance of their culture, attitudes and goals. This orientation was encouraged by our review of current HRA research activities. We therefore decided to envisage progress by identifying cognitive tendencies in the context of operating and simulator experience. For this purpose, advanced approaches for retrospective event analysis were discussed. Some orientations for improvements were proposed. By analyzing cases, various cognitive tendencies were identified, together with useful information about their context. Some of them match psychological findings already published in the literature, some of them are not covered adequately by the literature that we reviewed. Finally, this exploratory study shows that contextual and case-illustrated findings about cognitive tendencies provide useful help for the predictive identification of DUA in HRA. More research should be carried out to complement our findings and elaborate more detailed and systematic guidelines for using them in HRA studies

  8. Performance of Modular Prefabricated Architecture: Case Study-Based Review and Future Pathways

    Directory of Open Access Journals (Sweden)

    Fred Edmond Boafo

    2016-06-01

    Full Text Available Even though tightened building energy efficiency standards are implemented periodically in many countries, existing buildings continually consume a momentous quota of the total primary energy. Energy efficiency solutions range from material components to bulk systems. A technique of building construction, referred to as prefabricated architecture (prefab, is increasing in reputation. Prefab encompasses the offsite fabrication of building components to a greater degree of finish as bulk building structures and systems, and their assembly on-site. In this context, prefab improves the speed of construction, quality of architecture, efficiency of materials, and worker safety, while limiting environmental impacts of construction, as compared to conventional site-built construction practices. Quite recently, a 57 story skyscraper was built in 19 days using prefabricated modules. From the building physics point of view, the bulk systems and tighter integration method of prefab minimizes thermal bridges. This study seeks to clearly characterize the levels of prefab and to investigate the performance of modular prefab; considering acoustic constrain, seismic resistance, thermal behavior, energy consumption, and life cycle analysis of existing prefab cases and, thus, provides a dynamic case study-based review. Generally, prefab can be categorized into components, panels (2D, modules (3D, hybrids, and unitized whole buildings. On average, greenhouse gas emissions from conventional construction were higher than for modular construction, not discounting some individual discrepancies. Few studies have focused on monitored data on prefab and occupants’ comfort but additional studies are required to understand the public’s perception of the technology. The scope of the work examined will be of interest to building engineers, manufacturers, and energy experts, as well as serve as a foundational reference for future study.

  9. Optimization-based methodology for wastewater treatment plant synthesis – a full scale retrofitting case study

    DEFF Research Database (Denmark)

    Bozkurt, Hande; Gernaey, Krist; Sin, Gürkan

    2015-01-01

    Existing wastewater treatment plants (WWTP) need retrofitting in order to better handle changes in the wastewater flow and composition, reduce operational costs as well as meet newer and stricter regulatory standards on the effluent discharge limits. In this study, we use an optimization based...... technologies. The superstructure optimization problem is formulated as a Mixed Integer (non)Linear Programming problem and solved for different scenarios - represented by different objective functions and constraint definitions. A full-scale domestic wastewater treatment plant (265,000 PE) is used as a case...... framework to manage the multi-criteria WWTP design/retrofit problem for domestic wastewater treatment. The design space (i.e. alternative treatment technologies) is represented in a superstructure, which is coupled with a database containing data for both performance and economics of the novel alternative...

  10. A Process Re-engineering Framework for Reverse Logistics based on a Case Study

    Directory of Open Access Journals (Sweden)

    Hing Kai Chan

    2010-09-01

    Full Text Available Reverse logistics has gained increasing attention in recent years as a channel for companies to achieve operational excellence. The process involves manipulation of returned materials, or even products, which forms a pivotal role in sustainable development throughout the whole supply chains. To make reverse logistics possible, process re-engineering may need to be carried out. However, the processes involved in reengineering are practically complicated. Objectives, benefits, and applicability of any process re-engineering require a careful and detailed strategic planning. This paper aims to propose an easy-to-follow step-by-step framework for practitioners to perform process re-engineering, to learn and identify the critical issues in each step, and to be successful in applying process re-engineering in order to enhance reverse logistics performance. A learner-centred approach is adopted based on a case study of process re-engineering, which is demonstrated in the paper for explanation.

  11. Instant tsunami early warning based on real-time GPS – Tohoku 2011 case study

    Directory of Open Access Journals (Sweden)

    A. Hoechner

    2013-05-01

    Full Text Available Taking the 2011 Tohoku earthquake as an example, we demonstrate the ability of real-time GPS to provide qualified tsunami early warning within minutes. While in earlier studies we demonstrated the power of the so-called GPS shield concept based on synthetic data, we here present a complete processing chain starting from actual GPS raw data and fully simulate the situation as it would be in a warning center. The procedure includes processing of GPS observations with predicted high precision orbits, inversion for slip and computation of the tsunami propagation and coastal warning levels. We show that in case of the Tohoku earthquake, it would be feasible to provide accurate tsunami warning as soon as 3 min after the beginning of the earthquake.

  12. Agent-based simulation of pedestrian behaviour in closed spaces: a museum case study

    CERN Document Server

    Pluchino, Alessandro; Inturri, Giuseppe; Rapisarda, Andrea; Ignaccolo, Matteo

    2013-01-01

    In order to analyse the behaviour of pedestrians at the very fine scale, while moving along the streets, in open spaces or inside a building, simulation modelling becomes an essential tool. In these spatial environments, in the presence of unusual demand flows, simulation requires the ability to model the local dynamics of individual decision making and behaviour, which is strongly affected by the geometry, randomness, social preferences, local and collective behaviour of other individuals. The dynamics of people visiting and evacuating a museum offers an excellent case study along this line. In this paper we realize an agent-based simulation of the Castello Ursino museum in Catania (Italy), evaluating its carrying capacity in terms of both satisfaction of the visitors in regime of normal fruition and their safety under alarm conditions.

  13. Assessment of solar electrification in Cuba. A case study based on GIS for rural development

    Energy Technology Data Exchange (ETDEWEB)

    Pinedo, Irene; Dominguez, Javier [CIEMAT, Madrid (Spain). Energy Dept.; Rodriguez, Maria [Solar Energy Research Center (CIES), Santiago de Cuba (Cuba)

    2008-07-01

    A quarter of total world population, mainly in developing countries, are lacking of electricity. Due to social, economic and geographical differences, detail studies are needed in order to find the appropriate technology for each case. The rural electrification analysis of Guama municipality is based on the use of Geographical Information System (GIS) to define the best way of electrification using levelized electric cost (LEC) criterion to meet a particular demand. Applying SOLARGIS methodology, conventional and renewable energy technologies are compared in every non-electrified community. The analysis considers the social and geographical particularities of the area and shows a very high potential of remote sites to be electrified by means of photovoltaic systems. (orig.)

  14. The case-only independence assumption: associations between genetic polymorphisms and smoking among controls in two population-based studies

    OpenAIRE

    Hodgson, M Elizabeth; Olshan, Andrew F.; North, Kari E; Poole, Charles L; Zeng, Donglin; Tse, Chiu-Kit; Keku, Tope O; Galanko, Joseph; Sandler, Robert; Millikan, Robert C.

    2012-01-01

    The independence assumption for a case-only analysis of statistical interaction, i. e. that genetic (G) and environmental exposures (E) are not associated in the source population, is often checked in surrogate populations. Few studies have examined G-E association in empirical data, particularly in controls from population-based studies, the type of controls expected to provide the most valid surrogate estimates of G-E association. We used controls from two population-based case-control stud...

  15. Body Mass Index, Smoking and Hypertensive Disorders during Pregnancy: A Population Based Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Thuridur A Gudnadóttir

    Full Text Available While obesity is an indicated risk factor for hypertensive disorders of pregnancy, smoking during pregnancy has been shown to be inversely associated with the development of preeclampsia and gestational hypertension. The purpose of this study was to investigate the combined effects of high body mass index and smoking on hypertensive disorders during pregnancy. This was a case-control study based on national registers, nested within all pregnancies in Iceland 1989-2004, resulting in birth at the Landspitali University Hospital. Cases (n = 500 were matched 1:2 with women without a hypertensive diagnosis who gave birth in the same year. Body mass index (kg/m2 was based on height and weight at 10-15 weeks of pregnancy. We used logistic regression models to calculate odds ratios and corresponding 95% confidence intervals as measures of association, adjusting for potential confounders and tested for additive and multiplicative interactions of body mass index and smoking. Women's body mass index during early pregnancy was positively associated with each hypertensive outcome. Compared with normal weight women, the multivariable adjusted odds ratio for any hypertensive disorder was 1.8 (95% confidence interval, 1.3-2.3 for overweight women and 3.1 (95% confidence interval, 2.2-4.3 for obese women. The odds ratio for any hypertensive disorder with obesity was 3.9 (95% confidence interval 1.8-8.6 among smokers and 3.0 (95% confidence interval 2.1-4.3 among non-smokers. The effect estimates for hypertensive disorders with high body mass index appeared more pronounced among smokers than non-smokers, although the observed difference was not statistically significant. Our findings may help elucidate the complicated interplay of these lifestyle-related factors with the hypertensive disorders during pregnancy.

  16. A real options-based CCS investment evaluation model: Case study of China's power generation sector

    International Nuclear Information System (INIS)

    Highlights: → This paper establishes a carbon captures and storage (CCS) investment evaluation model. → The model is based on real options theory and solved by the Least Squares Monte Carlo (LSM) method. → China is taken as a case study to evaluate the effects of regulations on CCS investment. → The findings show that the current investment risk of CCS is high, climate policy having the greatest impact on CCS development. -- Abstract: This paper establishes a carbon capture and storage (CCS) investment evaluation model based on real options theory considering uncertainties from the existing thermal power generating cost, carbon price, thermal power with CCS generating cost, and investment in CCS technology deployment. The model aims to evaluate the value of the cost saving effect and amount of CO2 emission reduction through investing in newly-built thermal power with CCS technology to replace existing thermal power in a given period from the perspective of power generation enterprises. The model is solved by the Least Squares Monte Carlo (LSM) method. Since the model could be used as a policy analysis tool, China is taken as a case study to evaluate the effects of regulations on CCS investment through scenario analysis. The findings show that the current investment risk of CCS is high, climate policy having the greatest impact on CCS development. Thus, there is an important trade off for policy makers between reducing greenhouse gas emissions and protecting the interests of power generation enterprises. The research presented would be useful for CCS technology evaluation and related policy-making.

  17. Risk-Based, Hypothesis-Driven Framework for Hydrological Field Campaigns with Case Studies

    Science.gov (United States)

    Harken, B.; Rubin, Y.

    2014-12-01

    There are several stages in any hydrological modeling campaign, including: formulation and analysis of a priori information, data acquisition through field campaigns, inverse modeling, and prediction of some environmental performance metric (EPM). The EPM being predicted could be, for example, contaminant concentration or plume travel time. These predictions often have significant bearing on a decision that must be made. Examples include: how to allocate limited remediation resources between contaminated groundwater sites or where to place a waste repository site. Answering such questions depends on predictions of EPMs using forward models as well as levels of uncertainty related to these predictions. Uncertainty in EPM predictions stems from uncertainty in model parameters, which can be reduced by measurements taken in field campaigns. The costly nature of field measurements motivates a rational basis for determining a measurement strategy that is optimal with respect to the uncertainty in the EPM prediction. The tool of hypothesis testing allows this uncertainty to be quantified by computing the significance of the test resulting from a proposed field campaign. The significance of the test gives a rational basis for determining the optimality of a proposed field campaign. This hypothesis testing framework is demonstrated and discussed using various synthetic case studies. This study involves contaminated aquifers where a decision must be made based on prediction of when a contaminant will arrive at a specified location. The EPM, in this case contaminant travel time, is cast into the hypothesis testing framework. The null hypothesis states that the contaminant plume will arrive at the specified location before a critical amount of time passes, and the alternative hypothesis states that the plume will arrive after the critical time passes. The optimality of different field campaigns is assessed by computing the significance of the test resulting from each one

  18. Association Between Obesity and Asthma among Adults: A Hospital Based Case-Control Study

    Directory of Open Access Journals (Sweden)

    A.C. Mathew

    2009-01-01

    Full Text Available The aim is to study the association between obesity and asthma among adults by gender. The prevalences of both asthma and obesity have increased substantially in recent decades, leading to speculation that obese individuals might be at risk of asthma. However, the evidence of a relationship between obesity and asthma is not fully conclusive among adults. Hence we investigate the association between obesity and asthma among men and women using both measured weight and height and self-reported weight and height while controlling for the effects of the demographic and environmental factors. This case-control study involves a total of 159 adults; 53 cases and 106 controls enrolled in the month of July 2009 at PSG Hospitals. Body Mass Index (BMI was calculated based on measured weight and height. The Odds Ratio (OR with 95% confidence interval for obese individuals was estimated using logistic regression analysis with SPSS 11.5 for windows software (SPSS Inc., Chicago, Illinois. Multivariate logistic regression model was used to adjust all risk estimates for covariates. Obese women were found to have 9.14 times the risk of asthma than non obese women (95% confidence interval (CI:1.38, 35.68 after adjusting for covariates, such as age, education, environmental tobacco smoke and pet keeping. No significant association was observed among men although the direction of association is positive; adjusted odds ratio was 1.06 (95% CI: 0.12, 9.70. No significant association was observed between self-reported prevalence of obesity and asthma; among women, adjusted odds ratio = 4.33 (95% CI: 0.69, 27.37; and among men, adjusted odds ratio = 0.89 (95% CI: 0.11, 7.12. The study indicates a strong positive association between obesity and asthma among adult Indian women. The causal links between obesity and asthma by gender need to be further examined using prospective cohort studies.

  19. Vibration measurement-based simple technique for damage detection of truss bridges: A case study

    Directory of Open Access Journals (Sweden)

    Sudath C. Siriwardane

    2015-10-01

    Full Text Available The bridges experience increasing traffic volume and weight, deteriorating of components and large number of stress cycles. Therefore, assessment of the current condition of steel railway bridges becomes necessary. Most of the commonly available approaches for structural health monitoring are based on visual inspection and non-destructive testing methods. The visual inspection is unreliable as those depend on uncertainty behind inspectors and their experience. Also, the non-destructive testing methods are found to be expensive. Therefore, recent researches have noticed that dynamic modal parameters or vibration measurement-based structural health monitoring methods are economical and may also provide more realistic predictions to damage state of civil infrastructure. Therefore this paper proposes a simple technique to locate the damage region of railway truss bridges based on measured modal parameters. The technique is discussed with a case study. Initially paper describes the details of considered railway bridge. Then observations of visual inspection, material testing and in situ load testing are discussed under separate sections. Development of validated finite element model of the considered bridge is comprehensively discussed. Hence, variations of modal parameters versus position of the damage are plotted. These plots are considered as the main reference for locating the damage of the railway bridge in future periodical inspection by comparing the measured corresponding modal parameters. Finally the procedure of periodical vibration measurement and damage locating technique are clearly illustrated.

  20. Planning and Designing Web- Based Electronic Commerce: a case study in the insurance industry

    Directory of Open Access Journals (Sweden)

    Rolf Teubner

    1998-11-01

    Full Text Available Electronic Commerce (EC comprises new ways of doing business with customers, suppliers and other business partners. EC is enabled by information and communication technology, in particular the World Wide Web (in short, the Web. While numerous organisations have started to use the Web as an interface to clients and business partners, many have been disappointed by lower than expected response rates and higher than expected costs. One reason for non profitable Web based EC applications is that they do not reflect the strategic preconditions of EC. This lack may be due to deficits in the process of developing an EC-strategy for their Web application. Furthermore, there is a void of instruments and tools to support this process. In order to fill this void, this paper proposes two basic frameworks for planning a Web based EC application. The application of these frameworks is illustrated by the example of a medium seized insurance company. Based on experiences drawn from the case study, the proposed frameworks will be evaluated.

  1. Prediction of quantitative phenotypes based on genetic networks: a case study in yeast sporulation

    Directory of Open Access Journals (Sweden)

    Shen Li

    2010-09-01

    Full Text Available Abstract Background An exciting application of genetic network is to predict phenotypic consequences for environmental cues or genetic perturbations. However, de novo prediction for quantitative phenotypes based on network topology is always a challenging task. Results Using yeast sporulation as a model system, we have assembled a genetic network from literature and exploited Boolean network to predict sporulation efficiency change upon deleting individual genes. We observe that predictions based on the curated network correlate well with the experimentally measured values. In addition, computational analysis reveals the robustness and hysteresis of the yeast sporulation network and uncovers several patterns of sporulation efficiency change caused by double gene deletion. These discoveries may guide future investigation of underlying mechanisms. We have also shown that a hybridized genetic network reconstructed from both temporal microarray data and literature is able to achieve a satisfactory prediction accuracy of the same quantitative phenotypes. Conclusions This case study illustrates the value of predicting quantitative phenotypes based on genetic network and provides a generic approach.

  2. Construction of Agricultural University Students’ Entrepreneurship Incubation Base – Taking Sichuan Agricultural University as a Case Study

    OpenAIRE

    Xia Yao; Jianping Xie; Linchun He

    2013-01-01

    In the recent years, as an effective practice in university students’ entrepreneurship education, construction of university students’ entrepreneurship incubation base has been rapidly developed in different universities. This paper takes construction of the entrepreneurship incubation base in Sichuan Agricultural University as a case study, analyzes the current status of university students’ entrepreneurship incubation base and makes a discussion on establishment of management institution, f...

  3. Shrinkage Estimators for Robust and Efficient Inference in Haplotype-Based Case-Control Studies

    KAUST Repository

    Chen, Yi-Hau

    2009-03-01

    Case-control association studies often aim to investigate the role of genes and gene-environment interactions in terms of the underlying haplotypes (i.e., the combinations of alleles at multiple genetic loci along chromosomal regions). The goal of this article is to develop robust but efficient approaches to the estimation of disease odds-ratio parameters associated with haplotypes and haplotype-environment interactions. We consider "shrinkage" estimation techniques that can adaptively relax the model assumptions of Hardy-Weinberg-Equilibrium and gene-environment independence required by recently proposed efficient "retrospective" methods. Our proposal involves first development of a novel retrospective approach to the analysis of case-control data, one that is robust to the nature of the gene-environment distribution in the underlying population. Next, it involves shrinkage of the robust retrospective estimator toward a more precise, but model-dependent, retrospective estimator using novel empirical Bayes and penalized regression techniques. Methods for variance estimation are proposed based on asymptotic theories. Simulations and two data examples illustrate both the robustness and efficiency of the proposed methods.

  4. Estrogen and Alzheimer′s disease in Aging Population: Population based case-control study

    Institute of Scientific and Technical Information of China (English)

    Xia Hong; Zhen-xin Zhang; Hui Li; Jie hao Zhao; Jue-bin Huang; ling Wei

    2000-01-01

    Objective: Wc conducted a population based case-control study to evaluate the effect of estrogen associated variables in Alzhcimer′s disease. Methods: A total of 2995 female residents aged 55 years or older was drawn-by means of stratified multistage cluster sampling in urban and rural areas of Beijing. Wc collected gynecological data of 2995 females. Cases were females Alzheimer′s disease ascertained by DSM-Ⅳ criteria and NINCDS-ADRDA critcria. Controls were female residents whose MMSE scores upper than 50 percentage. Odds Ratio were calculated from Logistic models. Results: By a Logistic stepwise multiple regression model, we found that the risk of dementia in women increased with increasing age (OR per year, 1.21, 95%CI, 1.16 -1.27). The risk decreased with increased duration with menstrual cycles (OR per year, 0.8L, 95%CI, 0.68 to 0.97). The risk decreased with increased age of menopause (OR per year, 0.97, 95%CI, 0.91 to 1.04). The risk decreased in women ever suffered from uterine, ovary, or breast tumor (OR, 0.30, 95%C1:0.04- 2.28). Conclusion: The risk of AD decreased with increased duration of menstrual cycles and increased age of menopause and in wome ever suffered fiom uterine. ovary or breast tumor. These findings offers additional support for a protective influence of estrogen i AD.

  5. Using case studies based on a nursing conceptual model to teach medical-surgical nursing.

    Science.gov (United States)

    DeSanto-Madeya, Susan

    2007-10-01

    Nurse educators are continually challenged to develop teaching strategies that enhance students' critical thinking, problem-solving, and decision-making skills. Case studies are a creative learning strategy that fosters these skills through the use of in-depth descriptions of realistic clinical situations. Conceptual models of nursing provide a unique body of knowledge that can be used to guide construction of case studies and enhance application of didactic course content to nursing practice. In this column, the author discusses the use of case studies constructed within the context of the Roy adaptation model for a senior level medical-surgical nursing course. PMID:17911329

  6. Case Study of CPT-based Design Methods for Axial Capacity of Driven Piles in Sand

    DEFF Research Database (Denmark)

    Thomassen, Kristina; Ibsen, Lars Bo; Andersen, Lars Vabbersgaard

    2012-01-01

    loaded offshore driven piles in cohesionless soil has until now been the β-method given in API. The API-method is based on the effective overburden pressure at the depth in question. Previous studies show deviations between full-scale load test measurements of the axial pile capacity and the predictions...... found by means of the API-method. Compared to the test measurements, the API-method under-estimates the capacity of short piles (<20m) in dense sand, over-estimates the capacity of long piles in loose sand, and gives a shaft capacity less conservative for piles in tension than for piles in compression....... Thus, several CPT-based methods have been proposed for the design of offshore driven piles in cohesionless soil such as the UWA-05, ICP-05, and NGI-99 methods. This article treats a case study where the API-method as well as the UWA-05 and NGI-99 methods are compared using CPT-data from an offshore...

  7. A population-based case-control study of thyroid cancer.

    Science.gov (United States)

    Ron, E; Kleinerman, R A; Boice, J D; LiVolsi, V A; Flannery, J T; Fraumeni, J F

    1987-07-01

    A population-based case-control interview study of thyroid cancer (159 cases and 285 controls) was conducted in Connecticut. Prior radiotherapy to the head or neck was reported by 12% of the cases and 4% of the controls [odds ratio (OR) = 2.8; 95% confidence interval = 1.2-6.9]. Risk was inversely related to age at irradiation and was highest among children exposed under age 10. Few persons born after 1945 received prior radiotherapy, consistent with the declining use of radiation to treat benign conditions in the 1950's. Among females the radiogenic risk appeared to be potentiated by the number of subsequent live-births. Other significant risk factors included a history of benign thyroid nodules (OR = 33) or goiter (OR = 5.6). Miscarriage and multiparity increased risk but only among women who developed thyroid cancer before age 35 years. Consumption of shellfish (a rich source of iodine) seemed to increase the risk of follicular thyroid cancer, whereas consumption of goitrogen-containing vegetables appeared to reduce risk of total thyroid cancer, possibly because of their cruciferous nature. A significantly low risk was observed among persons of English descent, whereas Italian ancestry appeared to increase risk. No significant associations were found with a number of suspected risk factors: diagnostic x-rays, radioactive isotope scans, occupational radiation exposure, tonsillectomy, Jewish ethnicity, alcohol intake, cigarette smoking, oral contraceptives, lactation suppressants, menopausal estrogens, most other common medications, and water source. New associations were suggested for obesity among females (OR = 1.5), surgically treated benign breast disease (OR = 1.6), use of spironolactone (OR = 4.3) or vitamin D supplements (OR = 1.8), and a family history of thyroid cancer (OR = 5.2). About 9% of the incident thyroid cancers could be attributed to prior head and neck irradiation, 4% to goiter, and 17% to thyroid nodular disease, leaving the etiology of most

  8. A Case Study of a TPACK-Based Approach to Teacher Professional Development: Teaching Science with Blogs

    Science.gov (United States)

    Jaipal-Jamani, Kamini; Figg, Candace

    2015-01-01

    This paper presents a case study of a technology professional development initiative and illustrates how a workshop approach based on technology, pedagogy, and content knowledge (TPACK) was adapted for professional learning at a school site. The case further documents how three middle school science teacher participants developed knowledge about…

  9. Association between Herpesviruses and Chronic Periodontitis: A Meta-Analysis Based on Case-Control Studies

    Science.gov (United States)

    Wong, May. Chun. Mei; Feng, Xi-Ping; Lu, Hai-Xia; Xu, Wei

    2015-01-01

    Objective Numerous studies have investigated the associations between herpesviruses and chronic periodontitis; however, the results remain controversial. To derive a more precise estimation, a meta-analysis on all available studies was performed to identify the association between herpesviruses and chronic periodontitis. Methods A computerized literature search was conducted in December 2014 to identify eligible case-control studies from the PUBMED and EMBASE databases according to inclusion and exclusion criteria. Data were extracted and pooled odds ratios (OR) with 95% confidence intervals (CI) were used to assess the association between herpesviruses and risk of chronic periodontitis. A fixed or random effects model was determined based on a heterogeneity test. Sensitivity analysis was conducted to investigate stability and reliability. Publication bias was investigated using the Begg rank correlation test and Egger's funnel plot. Results Ten eligible studies were included to investigate the association between Epstein–Barr virus (EBV) and chronic periodontitis. The results showed that EBV has a significant association with chronic periodontitis compared with periodontally healthy group (OR = 5.74, 95% CI = 2.53–13.00, Pherpesvirus 7 (HHV-7) and chronic periodontitis risk (OR = 1.00, 95% CI = 0.21–4.86). Conclusion The findings of this meta-analysis suggest that two members of the herpesvirus family, EBV and HCMV, are significantly associated with chronic periodontitis. There is insufficient evidence to support associations between HSV, HHV-7 and chronic periodontitis. PMID:26666412

  10. A case study of secondary teachers facilitating a historical problem-based learning instructional unit

    Science.gov (United States)

    Pecore, John L.

    Current curriculum trends promote inquiry-based student-centered strategies as a way to foster critical thinking and learning. Problem-based learning (PBL), a type of inquiry focusing on an issue or "problem," is an instructional approach taught on the basis that science reform efforts increase scientific literacy. PBL is a constructivist approach to learning real life problems where understanding is a function of content, context, experiences, and learner goals; historical PBL situates the lesson in a historical context and provides opportunities for teaching NOS concepts. While much research exists on the benefits of historical PBL to student learning in general, more research is warranted on how teachers implement PBL in the secondary science curriculum. The purpose of this study was to examine the classroom-learning environment of four science teachers implementing a historical PBL instructional unit to identify the teachers' understandings, successes and obstacles. By identifying teachers' possible achievements and barriers with implementing a constructivist philosophy when executing historical PBL, educators and curriculum designers may improve alignment of the learning environment to constructivist principles. A qualitative interpretive case study guided this research study. The four participants of this study were purposefully and conveniently selected from biology teachers with at least three years of teaching experience, degrees in education, State Licensure, and completion of a PBL workshop. Data collection consisted of pre and post questionnaires, structured interviews, a card sort activity in which participants categorized instructional outcomes, and participant observations. Results indicated that the four teachers assimilated reform-based constructivist practices to fit within their preexisting routines and highlighted the importance of incorporating teachers' current systems into reform-based teacher instruction. While participating teachers

  11. Population-based case-control study of childhood leukemia in Shanghai

    Energy Technology Data Exchange (ETDEWEB)

    Shu, X.O.; Gao, Y.T.; Brinton, L.A.; Linet, M.S.; Tu, J.T.; Zheng, W.; Fraumeni, J.F. Jr.

    1988-08-01

    A population-based case-control interview study of 309 childhood leukemia cases and 618 healthy population control children was conducted in urban Shanghai, China. Like some studies in other countries, excess risks for both acute lymphocytic leukemia (ALL) and acute nonlymphocytic leukemia (ANLL) were associated with intrauterine and paternal preconception diagnostic x-ray exposure, and with maternal employment in the chemical and agricultural industries during pregnancy. ANLL was linked to maternal occupational exposure to benzene during pregnancy, whereas both ALL and ANLL were significantly associated with maternal exposure to gasoline and the patient's prior use of chloramphenicol. New findings, previously unsuspected, included an association of ANLL with younger maternal age at menarche (odds ratio (OR) = 4.3; 95% confidence interval (CI) = 1.3-13.9); a protective effect for long-term (greater than 1 year) use of cod liver oil containing vitamins A and D for both ALL (OR = 0.4; 95% CI = 0.2-0.9) and ANLL (OR = 0.3; 95% CI = 0.1-1.0); and excess risks of ANLL among children whose mothers were employed in metal refining and processing (OR = 4.6; 95% CI = 1.3-17.2) and of ALL associated with maternal occupational exposure to pesticides (OR = 3.5; 95% CI = 1.1-11.2). No relationships were found with late maternal age, certain congenital disorders, or familial occurrence, which have been related to childhood leukemia in other studies. In contrast with other reports, an excess of leukemia, primarily ANLL, occurred among second or later-born rather than firstborn children.

  12. Antioxidants and breast cancer risk- a population-based case-control study in Canada

    Directory of Open Access Journals (Sweden)

    Morrison Howard

    2011-08-01

    Full Text Available Abstract Background The effect of antioxidants on breast cancer is still controversial. Our objective was to assess the association between antioxidants and breast cancer risk in a large population-based case-control study. Methods The study population included 2,362 cases with pathologically confirmed incident breast cancer (866 premenopausal and 1,496 postmenopausal and 2,462 controls in Canada. Intakes of antioxidants from diet and from supplementation as well as other potential risk factors for breast cancer were collected by a self-reported questionnaire. Results Compared with subjects with no supplementation, 10 years or longer supplementation of zinc had multivariable-adjusted odds ratios (OR and 95% confidence intervals (CI of 0.46 (0.25-0.85 for premenopausal women, while supplementation of 10 years or longer of multiple vitamin, beta-carotene, vitamin C, vitamin E and zinc had multivariable-adjusted ORs (95% CIs of 0.74 (0.59, 0.92, 0.58 (0.36, 0.95, 0.79 (0.63-0.99, 0.75 (0.58, 0.97, and 0.47 (0.28-0.78, respectively, for postmenopausal women. No significant effect of antioxidants from dietary sources (including beta-carotene, alpha-carotene, lycopene, lutein and zeaxanthin, vitamin C, vitamin E, selenium and zinc or from supplementation less than 10 years was observed. Conclusions This study suggests that supplementation of zinc in premenopausal women, and supplementation of multiple vitamin, beta-carotene, vitamin C, vitamin E and zinc in postmenopausal women for 10 or more years may protect women from developing breast cancer. However, we were unable to determine the overall effect of total dose or intake from both diet and supplement.

  13. Population-based case-control study of childhood leukemia in Shanghai

    International Nuclear Information System (INIS)

    A population-based case-control interview study of 309 childhood leukemia cases and 618 healthy population control children was conducted in urban Shanghai, China. Like some studies in other countries, excess risks for both acute lymphocytic leukemia (ALL) and acute nonlymphocytic leukemia (ANLL) were associated with intrauterine and paternal preconception diagnostic x-ray exposure, and with maternal employment in the chemical and agricultural industries during pregnancy. ANLL was linked to maternal occupational exposure to benzene during pregnancy, whereas both ALL and ANLL were significantly associated with maternal exposure to gasoline and the patient's prior use of chloramphenicol. New findings, previously unsuspected, included an association of ANLL with younger maternal age at menarche (odds ratio [OR] = 4.3; 95% confidence interval (CI) = 1.3-13.9); a protective effect for long-term (greater than 1 year) use of cod liver oil containing vitamins A and D for both ALL (OR = 0.4; 95% CI = 0.2-0.9) and ANLL (OR = 0.3; 95% CI = 0.1-1.0); and excess risks of ANLL among children whose mothers were employed in metal refining and processing (OR = 4.6; 95% CI = 1.3-17.2) and of ALL associated with maternal occupational exposure to pesticides (OR = 3.5; 95% CI = 1.1-11.2). No relationships were found with late maternal age, certain congenital disorders, or familial occurrence, which have been related to childhood leukemia in other studies. In contrast with other reports, an excess of leukemia, primarily ANLL, occurred among second or later-born rather than firstborn children

  14. Risk factors for breast cancer by oestrogen receptor status: a population-based case-control study.

    OpenAIRE

    Cooper, J A; Rohan, T E; Cant, E. L.; Horsfall, D. J.; Tilley, W D

    1989-01-01

    Data from a population-based case-control study conducted in Adelaide, South Australia, and involving 451 case-control pairs, were analysed to determine whether the associations of menstrual, reproductive, dietary and other factors with risk of breast cancer differed by oestrogen receptor (ER) status. Data on ER status were available for 380 cases. The proportion of tumours which were ER+ increased with age, and there was a higher proportion of ER+ tumours in post-menopausal than in premenopa...

  15. Trade Union-based Workplace Learning: A Case Study in Workplace Reorganization and Worker Knowledge Production.

    Science.gov (United States)

    Sawchuk, Peter H.

    2001-01-01

    A case study of Canada's telecommunications industry found the union engaged in education and research that helped build the potential for workplace democracy. However, scarce resources for these activities and management concerns about worker empowerment constrained progressive change. (SK)

  16. Determinants of Mortality from Severe Dengue in Brazil: A Population-Based Case-Control Study

    OpenAIRE

    Hentzy Moraes, Giselle; de Fátima Duarte, Eliane; Carmen Duarte, Elisabeth

    2013-01-01

    Although increases in severity of mortality from dengue infection have been observed in Brazil, their determinants are not fully known. A case–control study was conducted by using the National Notifiable Diseases Surveillance System, including patients with severe dengue during 2000–2005. Cases were defined as patients that died and controls were those who survived. Hierarchical multivariate logistic regression was performed. During the study period, there were 12,321 severe cases of dengue a...

  17. Creating the Future of Evidence-Based Nutrition Recommendations: Case Studies from Lipid Research.

    Science.gov (United States)

    Dwyer, Johanna T; Rubin, Kristin H; Fritsche, Kevin L; Psota, Tricia L; Liska, DeAnn J; Harris, William S; Montain, Scott J; Lyle, Barbara J

    2016-07-01

    Strategic translational research is designed to address research gaps that answer specific guidance questions. It provides translational value with respect to nutrition guidance and regulatory and public policy. The relevance and the quality of evidence both matter in translational research. For example, design decisions regarding population, intervention, comparator, and outcome criteria affect whether or not high-quality studies are considered relevant to specific guidance questions and are therefore included as evidence within the context of systematic review frameworks used by authoritative food and health organizations. The process used in systematic reviews, developed by the USDA for its Nutrition Evidence Library, is described. An eating pattern and cardiovascular disease (CVD) evidence review is provided as an example, and factors that differentiated the studies considered relevant and included in that evidence base from those that were excluded are noted. Case studies on ω-3 (n-3) fatty acids (FAs) and industrial trans-FAs illustrate key factors vital to relevance and translational impact, including choice of a relevant population (e.g., healthy, at risk, or diseased subjects; general population or high-performance soldiers); dose and form of the intervention (e.g., food or supplement); use of relevant comparators (e.g., technically feasible and realistic); and measures for both exposure and outcomes (e.g., inflammatory markers or CVD endpoints). Specific recommendations are provided to help increase the impact of nutrition research on future dietary guidance, policy, and regulatory issues, particularly in the area of lipids. PMID:27422509

  18. Antipsychotics and risk of venous thromboembolism: A population-based case-control study

    Directory of Open Access Journals (Sweden)

    Anna K Jönsson

    2009-03-01

    Full Text Available Anna K Jönsson1, Erzsebet Horváth-Puhó2, Staffan Hägg3, Lars Pedersen4, Henrik Toft Sørensen41Nordic School of Public Health, Gothenburg, Sweden; 2Centre for Registry Research, Aarhus C, Denmark; 3Division of Clinical Pharmacology, Linköping University, Linköping, Sweden; 4Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus C, DenmarkAbstract: During the last decade, the risk of venous thromboembolism (VTE has been reported in users of antipsychotic drugs. However, the reports have been inconclusive. This study aimed to determine the relative risk of VTE in antipsychotic drug users. Using data from medical databases in North Jutland and Aarhus Counties, Denmark, and the Danish Civil Registration System, we identified 5,999 cases with a first-time diagnosis of VTE and, based on risk set sampling, 59,990 sex- and age-matched population controls during 1997–2005. Users of antipsychotic drugs were identified from population-based prescription databases and categorized based on filled prescriptions prior to admission date for VTE or index date for controls as current (at least one prescription within 90 days, recent (at least one prescription within 91–180 days, former (at least one prescription within 181–365 days or nonusers (no recorded prescription within 365 days. Compared with nonusers, current users of any antipsychotic drugs had an increased risk of VTE (adjusted relative risk [ARR]: 1.99, 95% confidence interval [CI]: 1.69–2.34. Former users of any antipsychotic drugs had a nonsignificant elevated risk of VTE compared with nonusers (ARR: 1.54, 95% CI: 0.99–2.40, p-value: 0.056. In conclusion, users of antipsychotic drugs have an increased risk of VTE, compared with nonusers, which might be due to the treatment itself, to lifestyle factors, to the underlying disease, or to residual confounding. Keywords: antipsychotic agents, venous thromboembolism, adverse effects, case-control study

  19. Case Study Teaching

    Science.gov (United States)

    Herreid, Clyde Freeman

    2011-01-01

    This chapter describes the history of case study teaching, types of cases, and experimental data supporting their effectiveness. It also describes a model for comparing the efficacy of the various case study methods. (Contains 1 figure.)

  20. Does marriage protect against hospitalization with pneumonia? A population-based case-control study

    Directory of Open Access Journals (Sweden)

    Mor A

    2013-10-01

    Full Text Available Anil Mor, Sinna P Ulrichsen, Elisabeth Svensson, Klara Berencsi, Reimar W Thomsen Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark Background: To reduce the increasing burden of pneumonia hospitalizations, we need to understand their determinants. Being married may decrease the risk of severe infections, due to better social support and healthier lifestyle. Patients and methods: In this population-based case-control study, we identified all adult patients with a first-time pneumonia-related hospitalization between 1994 and 2008 in Northern Denmark. For each case, ten sex- and age-matched population controls were selected from Denmark's Civil Registration System. We performed conditional logistic regression analysis to estimate the odds ratios (ORs for pneumonia hospitalization among persons who were divorced, widowed, or never married, as compared with married persons, adjusting for age, sex, 19 different comorbidities, alcoholism-related conditions, immunosuppressant use, urbanization, and living with small children. Results: The study included 67,162 patients with a pneumonia-related hospitalization and 671,620 matched population controls. Compared with controls, the pneumonia patients were more likely to be divorced (10% versus 7% or never married (13% versus 11%. Divorced and never-married patients were much more likely to have previous diagnoses of alcoholism-related conditions (18% and 11%, respectively compared with married (3% and widowed (6% patients. The adjusted OR for pneumonia-related hospitalization was increased, at 1.29 (95% confidence interval [CI]: 1.25-1.33 among divorced; 1.15 (95% CI: 1.12-1.17 among widowed; and 1.33 (95% CI: 1.29-1.37 among never-married individuals as compared with those who were married. Conclusion: Married individuals have a decreased risk of being hospitalized with pneumonia compared with never-married, divorced, and widowed patients

  1. Strategic approaches to simulation-based education: A case study from Australia

    Directory of Open Access Journals (Sweden)

    Debra Nestel

    2013-01-01

    Full Text Available This paper addresses some of the challenges met when developing widely distributed, broad spectrum, simulation-based education (SBE for health professionals, such as resource duplication, inconsistent facilities utilization, discipline-specific silos, and the intersection of academic institutions and health services sectors. We examine three primary contributors to successful simulation-based practices - strategic planning, program development, and professional networks. Further, we provide examples of how each of these contributors function at different levels to assure comprehensive, yet sustainable approaches to implementing SBE for greatest impact at national, state, regional, and institutional levels. We draw on the example of Australia and its state and regional government structures, including the challenges in providing health services across a widely variable geography and population distribution. The types of health services and issues relating to health provision and management reflect those found in many western countries. Our hope is that the experiences gained at each level of governance within Australia may inform similar, successful development in other countries. We emphasize the importance of leadership and investment at the national level that serves to inform state, regional, and institutional efforts through a "trickle down" effect. Although evaluation of the strategic planning, program development, and professional networks described in this case study is still ongoing, their preliminary coordination has resulted in significant investment and support at all levels.

  2. Problem-based learning spanning real and virtual words: a case study in Second Life

    Directory of Open Access Journals (Sweden)

    Judith Good

    2008-12-01

    Full Text Available There is a growing use of immersive virtual environments for educational purposes. However, much of this activity is not yet documented in the public domain, or is descriptive rather than analytical. This paper presents a case study in which university students were tasked with building an interactive learning experience using Second Life as a platform. Both problem-based learning and constructionism acted as framing pedagogies for the task, with students working in teams to design and build a learning experience which could potentially meet the needs of a real client in innovative ways which might not be possible in real life. A process account of the experience is provided, which examines how the pedagogies and contexts (real and virtual influence and enhance each other. The use of a virtual environment, combined with problem-based learning and constructionism, subtly changed the nature of the instructor–student relationship, allowed students to explore ‘problematic problems' in a motivating and relevant manner, provided students with greater ownership over their work, and allowed problems to be set which were flexible, but at the same time allowed for ease of assessment.

  3. Aircraft operational reliability—A model-based approach and a case study

    International Nuclear Information System (INIS)

    The success of an aircraft mission is subject to the fulfillment of some operational requirements before and during each flight. As these requirements depend essentially on the aircraft system components and the mission profile, the effects of failures can be very severe if they are not anticipated. Hence, one should be able to assess the aircraft operational reliability with regard to its missions in order to be able to cope with failures. We address aircraft operational reliability modeling to support maintenance planning during the mission achievement. We develop a modeling approach, based on a meta-model that is used as a basis: (i) to structure the information needed to assess aircraft operational reliability and (ii) to build a stochastic model that can be tuned dynamically, in order to take into account the aircraft system operational state, a mission profile and the maintenance facilities available at the flight stop locations involved in the mission. The aim is to enable operational reliability assessment online. A case study, based on an aircraft subsystem, is considered for illustration using the Stochastic Activity Networks (SANs) formalism

  4. Radiosurgery for skull base meningiomas: a study on 230 cases in Iranian Gamma Knife Center

    Directory of Open Access Journals (Sweden)

    Ali Bitara M

    2010-06-01

    Full Text Available "n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Meningiomas are among the most common tumors of the brain. Skull base meningiomas comprise s major part of brain meningiomas. They are difficult to treat because of proximity to major vital neuro-vascular structures which makes their surgical resection hazardous and fraught with a high rate of complications. Radiosurgery is considered as an alternative efficient way to treat them, which targets the tumor and its supplying vasculature. The standard treatment consists of tumor eradication and its supplying vessels through homogeneous dose of 201 rays of cobalt 60 source."n"nMethods: In a case-series study, we report 230 meningiomas referred to Iraninan Gamma Knife Center, treated by radiosurgery with type C Gamma Knife. Radio-surgery was performed at a mean dose of 15 Gy and 50% isodose."n"nResults: Two hundred and thirty of all meningioma cases refered to our institute were skull base lesions. Eighty (35% were new case and the rest were previously treated microsurgically one or more times. None of the patients died after treatment and the most common post-operative complications were headache (30 patients and peri-tumoral edema (12 patients."n"nConclusion: Tumoral control is defined as reduced tumor volume

  5. Case study of inventory difference (ID) computation and analysis based on radiochemical plant model

    International Nuclear Information System (INIS)

    Inventory Difference (ID) computation and analysis is an urgent task of high priority in the field of nuclear material control and accountancy. In this paper this task is considered from the point of view of studying different practical cases (case study) in order to upgrade qualification of nuclear material control and accounting specialists. Training courses which are regularly held in Russian Methodological and Training Centre, SCI, Obninsk training center and discussions with specialists during those courses confirm how urgent this task is. In this paper the model of radiochemical plant is considered, for this case the practical tasks and solutions have been developed. The case study given in the paper is the first version of ID calculation and analysis for a radiochemical plant

  6. Teaching Pharmacology by Case Study.

    Science.gov (United States)

    Jordan, Sue

    1997-01-01

    Using pharmacology case studies with nursing students encourages theory-practice links and infuses real-life content. Cases provide rich qualitative data for evaluating curriculum. However, they are not a substitute for evidence-based practice. (SK)

  7. Natural Learning Case Study Archives

    Science.gov (United States)

    Lawler, Robert W.

    2015-01-01

    Natural Learning Case Study Archives (NLCSA) is a research facility for those interested in using case study analysis to deepen their understanding of common sense knowledge and natural learning (how the mind interacts with everyday experiences to develop common sense knowledge). The database comprises three case study corpora based on experiences…

  8. A Collective Case Study of Secondary Students' Model-Based Inquiry on Natural Selection through Programming in an Agent-Based Modeling Environment

    Science.gov (United States)

    Xiang, Lin

    2011-01-01

    This is a collective case study seeking to develop detailed descriptions of how programming an agent-based simulation influences a group of 8th grade students' model-based inquiry (MBI) by examining students' agent-based programmable modeling (ABPM) processes and the learning outcomes. The context of the present study was a biology unit on…

  9. Integrating EMDR into an evolutionary-based therapy for depression: a case study.

    Science.gov (United States)

    Krupnik, Valery

    2015-05-01

    We present an intervention in a case of major depression, where eye movement desensitization and reprocessing (EMDR) therapy was integrated into an evolutionary-based psychotherapy for depression. At the end of the treatment and at follow up assessment we observed a more accepting disposition and decreased depressive but not anxiety symptoms. PMID:25984310

  10. Integrating EMDR into an evolutionary-based therapy for depression: a case study

    OpenAIRE

    Krupnik, Valery

    2015-01-01

    Key Clinical Message We present an intervention in a case of major depression, where eye movement desensitization and reprocessing (EMDR) therapy was integrated into an evolutionary-based psychotherapy for depression. At the end of the treatment and at follow up assessment we observed a more accepting disposition and decreased depressive but not anxiety symptoms.

  11. The Change towards a Teaching Methodology Based on Competences: A Case Study in a Spanish University

    Science.gov (United States)

    Gonzalez, Jose Maria G.; Arquero Montaño, Jose Luis; Hassall, Trevor

    2014-01-01

    The European Higher Education Area (EHEA) has promoted the implementation of a teaching methodology based on competences. Drawing on New Institutional Sociology, the present work aims to identify and improve knowledge concerning the factors which are hindering that change in the Spanish university system. This is investigated using a case study…

  12. Service Quality of Online Shopping Platforms: A Case-Based Empirical and Analytical Study

    Directory of Open Access Journals (Sweden)

    Tsan-Ming Choi

    2013-01-01

    Full Text Available Customer service is crucially important for online shopping platforms (OSPs such as eBay and Taobao. Based on the well-established service quality instruments and the scenario of the specific case on Taobao, this paper focuses on exploring the service quality of an OSP with an aim of revealing customer perceptions of the service quality associated with the provided functions and investigating their impacts on customer loyalty. By an empirical study, this paper finds that the “fulfillment and responsiveness” function is significantly related to the customer loyalty. Further analytical study is conducted to reveal that the optimal service level on the “fulfillment and responsiveness” function for the risk averse OSP uniquely exists. Moreover, the analytical results prove that (i if the customer loyalty is more positively correlated to the service level, it will lead to a larger optimal service level, and (ii the optimal service level is independent of the profit target, the source of uncertainty, and the risk preference of the OSP.

  13. Caesarean Delivery and Postpartum Maternal Mortality: A Population-Based Case Control Study in Brazil

    Science.gov (United States)

    Esteves-Pereira, Ana Paula; Deneux-Tharaux, Catherine; Nakamura-Pereira, Marcos; Saucedo, Monica; Bouvier-Colle, Marie-Hélène; Leal, Maria do Carmo

    2016-01-01

    Background Cesarean delivery rates continue to increase worldwide and reached 57% in Brazil in 2014. Although the safety of this surgery has improved in the last decades, this trend is a concern because it carries potential risks to women’s health and may be a modifiable risk factor of maternal mortality. This paper aims to investigate the risk of postpartum maternal death directly associated with cesarean delivery in comparison to vaginal delivery in Brazil. Methods This was a population-based case—control study performed in eight Brazilian states. To control for indication bias, deaths due to antenatal morbidity were excluded. We included 73 cases of postpartum maternal deaths from 2009–2012. Controls were selected from the Birth in Brazil Study, a 2011 nationwide survey including 9,221 postpartum women. We examined the association of cesarean section and postpartum maternal death by multivariate logistic regression, adjusting for confounders. Results After controlling for indication bias and confounders, the risk of postpartum maternal death was almost three-fold higher with cesarean than vaginal delivery (OR 2.87, 95% CI 1.63–5.06), mainly due to deaths from postpartum hemorrhage and complications of anesthesia. Conclusion Cesarean delivery is an independent risk factor of postpartum maternal death. Clinicians and patients should consider this fact in balancing the benefits and risks of the procedure. PMID:27073870

  14. 3D Geological Modeling and Visualization of Rock Masses Based on Google Earth: A Case Study

    CERN Document Server

    Mei, Gang; Xu, Nengxiong

    2013-01-01

    Google Earth (GE) has become a powerful tool for geological modeling and visualization. An interesting and useful feature of GE, Google Street View, can allow the GE users to view geological structure such as layers of rock masses at a field site. In this paper, we introduce a practical solution for building 3D geological models for rock masses based on the data acquired by use with GE. A real study case at Haut-Barr, France is presented to demonstrate our solution. We first locate the position of Haut-Barr in GE, and then determine the shape and scale of the rock masses in the study area, and thirdly acquire the layout of layers of rock masses in the Google Street View, and finally create the approximate 3D geological models by extruding and intersecting. The generated 3D geological models can simply reflect the basic structure of the rock masses at Haut-Barr, and can be used for visualizing the rock bodies interactively.

  15. Overview of energy-conserving development planning and design techniques based on five case studies

    Energy Technology Data Exchange (ETDEWEB)

    1980-06-01

    Findings and recommendations are presented of a review of five case studies of ways to conserve energy through development planning and site design in communities. Two approaches were used. In the first approach, a conventional, pre-existing plan was analyzed to determine potential energy use. Once energy-conservation options were identified and evaluated, the conventional plan was modified by employing those options. This approach was used in The Woodlands, Burke Center, and Radisson studies. In the second approach, energy-conservation options are independently identified and evaluated. Those options that passed specific criteria screening were then utilized in developing one or more totally new plans based on energy objectives. This approach was used in Greenbrier and Shenandoah. Radisson is a new town on the outskirts of Syracuse, New York. Greenbrier is a 3000 acre planned community adjacent to Norfolk and Virginia Beach. Shenandoah is a proposed new town in the Atlanta urbanized area. The Woodlands is a new community under development north of Houston. Burke Center is a residential planned unit development in Fairfax County, Virgnia. (MCW)

  16. Epilepsy and risk of suicide: a population-based case-control study

    DEFF Research Database (Denmark)

    Christensen, Jakob; Vestergaard, Mogens; Mortensen, Preben Bo;

    2007-01-01

    sex, birth year, and calendar date, were assigned to each suicide case. FINDINGS: We identified 21 169 cases of suicide and 423 128 controls. 492 (2.32%) individuals who committed suicide had epilepsy compared with 3140 (0.74%) controls, corresponding to a three times higher risk (rate ratio [RR] 3......BACKGROUND: Studies have linked epilepsy with an increased suicide risk, but the association might be modified by psychiatric, demographic, and socioeconomic factors. METHODS: Suicide cases were identified in the Cause of Death Register in Denmark from 1981 to 1997. Up to 20 controls, matched by...

  17. Implementation and utilisation of community-based mortality surveillance: a case study from Chad

    Directory of Open Access Journals (Sweden)

    Bowden Sarah

    2012-11-01

    Full Text Available Abstract Background Prospective surveillance is a recognised approach for measuring death rates in humanitarian emergencies. However, there is limited evidence on how such surveillance should optimally be implemented and on how data are actually used by agencies. This case study investigates the implementation and utilisation of mortality surveillance data by Médecins Sans Frontières (MSF in eastern Chad. We aimed to describe and analyse the community-based mortality surveillance system, trends in mortality data and the utilisation of these data to guide MSF’s operational response. Methods The case study included 5 MSF sites including 2 refugee camps and 3 camps for internally displaced persons (IDPs. Data were obtained through key informant interviews and systematic review of MSF operational reports from 2004–2008. Results Mortality data were collected using community health workers (CHWs. Mortality generally decreased progressively. In Farchana and Breidjing refugee camps, crude death rates (CDR decreased from 0.9 deaths per 10,000 person-days in 2004 to 0.2 in 2008 and from 0.7 to 0.1, respectively. In Gassire, Ade and Kerfi IDP camps, CDR decreased from 0.4 to 0.04, 0.3 to 0.04 and 1.0 to 0.3. Death rates among children under 5 years (U5DR followed similar trends. CDR and U5DR crossed emergency thresholds in one site, Kerfi, where CDR rapidly rose to 2.1 and U5DR to 7.9 in July 2008 before rapidly decreasing to below emergency levels by September 2008. Discussion Mortality data were used regularly to monitor population health status and on two occasions as a tool for advocacy. Lessons learned included the need for improved population estimates and standardized reporting procedures for improved data quality and dissemination; the importance of a simple and flexible model for data collection; and greater investment in supervising CHWs. Conclusions This model of community based mortality surveillance can be adapted and used by

  18. Talent Management: A Research Based Case Study in the GCC Region

    OpenAIRE

    Abhilasha Singh; Jones, David B; Nicholas Hall

    2012-01-01

    The present case study describes the talent landscape in the Gulf Cooperation Council region, as it exists today.With unprecedented economic growth and investment in infrastructure by the Government, there is anopportunity to increase the proportion of GCC nationals to engage in private and/or entrepreneurial enterprises.The case describes the various challenges and limitations in talent attraction and retention for private sectorcompanies to compete with government organizations that are abl...

  19. Education and occupations preceding Parkinson disease: a population-based case-control study.

    OpenAIRE

    Frigerio, Roberta; Elbaz, Alexis; Sanft, Kevin,; Peterson, Brett,; Bower, James; Ahlskog, J. Eric; Grossardt, Brandon,; de Andrade, Mariza; Maraganore, Demetrius,; Rocca, Walter

    2005-01-01

    OBJECTIVE: To investigate the association of Parkinson disease (PD) with education and occupations using a case-control study design. METHODS: The authors used the medical records-linkage system of the Rochester Epidemiology Project to identify all subjects who developed PD in Olmsted County, MN, from 1976 through 1995. Each incident case was matched by age (+/-1 year) and sex to a general population control. The authors collected information about education and occupations using two independ...

  20. Comparative evaluation of activity-based costing and variable costing: a case study at IPEN

    International Nuclear Information System (INIS)

    This research aims to compare the results with the application of Activity Based Costing and Variable Costing methods in an administrative unit of the Brazilian Federal Government: the Radiopharmacy Facility of IPEN (Institute for Energy and Nuclear Research), which produces radiopharmaceuticals products and develops R and D activities. Faced with the need to adopt a more economical and managerial public administration, this research has provided information to assess which of the two costing methods proves more suitable for cost management in that unit. The research is exploratory and a single-case study. We traced about 80% of material costs by observation 'in loco' of the entire manufacturing process of technetium generator, which represents the main product in terms of production volume and revenues. The results show that the Contribution Margin Variable Costing of 29.12% is very close to the operating income of 28.86%, ahead of support activities, obtained by ABC. It is also noted that the operational result of the product does not change by using either one or another costing method. In the two costing methods the end result is 24.20%. This occurs because the production is on demand. There is no inventory of finished product because it is radioactive. The research has revealed that both methods provide useful information for the management and optimization of costs and results of processes/activities, and that the two methods, in this case, may be used in an integrated and complementary approach, enabling to use the best information content of both. (author)

  1. UAV-based Natural Hazard Management in High-Alpine Terrain - Case Studies from Austria

    Science.gov (United States)

    Sotier, Bernadette; Adams, Marc; Lechner, Veronika

    2015-04-01

    Unmanned Aerial Vehicles (UAV) have become a standard tool for geodata collection, as they allow conducting on-demand mapping missions in a flexible, cost-effective manner at an unprecedented level of detail. Easy-to-use, high-performance image matching software make it possible to process the collected aerial images to orthophotos and 3D-terrain models. Such up-to-date geodata have proven to be an important asset in natural hazard management: Processes like debris flows, avalanches, landslides, fluvial erosion and rock-fall can be detected and quantified; damages can be documented and evaluated. In the Alps, these processes mostly originate in remote areas, which are difficult and hazardous to access, thus presenting a challenging task for RPAS data collection. In particular, the problems include finding suitable landing and piloting-places, dealing with bad or no GPS-signals and the installation of ground control points (GCP) for georeferencing. At the BFW, RPAS have been used since 2012 to aid natural hazard management of various processes, of which three case studies are presented below. The first case study deals with the results from an attempt to employ UAV-based multi-spectral remote sensing to monitor the state of natural hazard protection forests. Images in the visible and near-infrared (NIR) band were collected using modified low-cost cameras, combined with different optical filters. Several UAV-flights were performed in the 72 ha large study site in 2014, which lies in the Wattental, Tyrol (Austria) between 1700 and 2050 m a.s.l., where the main tree species are stone pine and mountain pine. The matched aerial images were analysed using different UAV-specific vitality indices, evaluating both single- and dual-camera UAV-missions. To calculate the mass balance of a debris flow in the Tyrolean Halltal (Austria), an RPAS flight was conducted in autumn 2012. The extreme alpine environment was challenging for both the mission and the evaluation of the aerial

  2. GIS-based landscape design research: Stourhead landscape garden as a case study

    Directory of Open Access Journals (Sweden)

    Steffen Nijhuis

    2016-11-01

    Full Text Available Landscape design research is important for cultivating spatial intelligence in landscape architecture. This study explores GIS (geographic information systems as a tool for landscape design research - investigating landscape designs to understand them as architectonic compositions (architectonic plan analysis. The concept ‘composition’ refers to a conceivable arrangement, an architectural expression of a mental construct that is legible and open to interpretation. Landscape architectonic compositions and their representations embody a great wealth of design knowledge as objects of our material culture and reflect the possible treatment of the ground, space, image and program as a characteristic coherence. By exploring landscape architectonic compositions with GIS, design researchers can acquire design knowledge that can be used in the creation and refinement of a design. The research aims to identify and illustrate the potential role of GIS as a tool in landscape design research, so as to provide insight into the possibilities and limitations of using GIS in this capacity. The critical, information-oriented case of Stourhead landscape garden (Wiltshire, UK, an example of a designed landscape that covers the scope and remit of landscape architecture design, forms the heart of the study. The exploration of Stourhead by means of GIS can be understood as a plausibility probe. Here the case study is considered a form of ‘quasi-experiment’, testing the hypothesis and generating a learning process that constitutes a prerequisite for advanced understanding, while using an adjusted version of the framework for landscape design analysis by Steenbergen and Reh (2003. This is a theoretically informed analytical method based on the formal interpretation of the landscape architectonic composition addressing four landscape architectonic categories: the basic, the spatial, the symbolic and the programmatic form. This study includes new aspects to be

  3. Project management case studies

    CERN Document Server

    Kerzner, Harold R

    2013-01-01

    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  4. Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: population based case-control study

    OpenAIRE

    Islami, Farhad; Pourshams, Akram; Nasrollahzadeh, Dariush; Kamangar, Farin; Fahimi, Saman; Shakeri, Ramin; Abedi-Ardekani, Behnoush; Merat, Shahin; Vahedi, Homayoon; Semnani, Shahryar; Abnet, Christian C.; Brennan, Paul; Møller, Henrik; Saidi, Farrokh; Dawsey, Sanford M.

    2009-01-01

    Objective To investigate the association between tea drinking habits in Golestan province, northern Iran, and risk of oesophageal squamous cell carcinoma. Design Population based case-control study. In addition, patterns of tea drinking and temperature at which tea was drunk were measured among healthy participants in a cohort study. Setting Golestan province, northern Iran, an area with a high incidence of oesophageal squamous cell carcinoma. Participants 300 histologically proved cases of o...

  5. A Case Study of Student Engagement in Collaborative Group Learning in a Blended Community Based (Service) Learning Module

    OpenAIRE

    McGarrigle, John

    2009-01-01

    Abstract: A participatory action research case study employed mixed methods to examine student collaboration and engagement in a Community Based (Service) learning module. A quasi experimental testing of Coates (2007) typology of student engagement found low agreement between students and lecturers in assigning the terms, passive, intense, independent or collaborative to student postings to discussion fora. Evidence from this case study found greater student collaboration in discussion fora w...

  6. Water resources regulation based on ET management - A case study on Huabei Plain in China

    Science.gov (United States)

    Wang, S.

    2012-04-01

    objective-ET distribution method, and the connections and interactions among ET water rights, surface-water rights and groundwater rights are studied. A case study is carried out to test the ET method over an agricultural area on Huabei Plain. SWAT model is employed to compare three water-saving scenarios. The results will lead to the practical water allocation scheme that is suitable in the study area.

  7. Project-based learning in a high school engineering program: A case study

    Science.gov (United States)

    France, Todd

    Generating greater student interest in science, technology, engineering, and mathematics (STEM) has been a major topic of discussion among educators, policymakers, and researchers in recent years, as increasing the number of graduates in these fields is widely considered a necessary step for sustaining the progress of today's society. Fostering this interest must occur before students reach college, and substantial efforts have been made to engage students at K-12 levels in STEM-focused learning. Attempts to involve students in engineering, a vital and growing profession, yet one in which students often have little experience, have frequently emphasized the design and construction of physical products, a practice supported by project-based learning. This thesis examines the environment of an engineering high school course that employed the project-based model. The course is part of a dedicated curricular program which aims to provide students with positive experiences in engineering-related activities while also preparing them for the rigors of college. A case study was conducted to provide insight into the benefits and drawbacks of the learning model. The study's outcomes are intended to provide guidance to educators participating in the design and/or facilitation of project-based activities, particularly those involved with engineering education. The research was performed using a qualitative approach. Long-term engagement with course participants was deemed critical to gaining a comprehensive understanding of the interactions and events that transpired on a daily basis. Nine educators involved with the program were interviewed, as were nineteen of the course's thirty-nine students. A wealth of other relevant data -- including surveys, field notes, and evaluations of student work -- was compiled for analysis as well. The study findings suggest that experiences in problem solving and teamwork were the central benefits of the course. Limitations existed due to a

  8. Unit Sizing and Cost Analysis of Renewable Energy based Hybrid Power Generation System - A Case Study

    Directory of Open Access Journals (Sweden)

    Nitin AGARWAL

    2014-01-01

    Full Text Available A simulation model is developed for optimal sizing and analysis of a PV-diesel-battery based hybrid power generation system with the objectives to minimize life cycle cost and CO2 emission, while maintaining the desired system autonomy. A case study of a boy’s hostel in Moradabad district is taken for analysis purposes. It has 91 rooms with a capacity of 3 boys in each room. The decision variables included in the optimization methodology are total PV area, number of PV modules of 600 Wp, diesel generator power, fuel consumption per year and number of 24 V and 150 Ah batteries. The simulation result shows that the PV percentage of 86 % and diesel penetration of 14 % gives the most optimized solution with minimum LCC of $110,547 and average CO2 emission of 28 kg/day. The developed model has been validated by comparing its results with earlier research work.doi:10.14456/WJST.2014.24

  9. Communicating Archaeological Risk with Web-Based Virtual Reality: A Case Study

    Directory of Open Access Journals (Sweden)

    Giacomo Landeschi

    2011-12-01

    Full Text Available In the last decade 3D technologies have become very effective and are widely used for managing and interpreting archaeological data. A better way to perceive, understand and communicate Cultural Heritage has been achieved through VR applications, which have enabled archaeologists to make both reconstructions of original landscapes and to put artefacts in their original context. Furthermore, the exponential growth of the Web has led to a massive availability of digital content, even in the field of Cultural Heritage, that can be accessed in an easier and more intuitive manner by a broader audience. The case study presented here is designed to demonstrate the potential importance of Web3D technologies for communicating specific research aspects, such as the ones connected to the GIS-based spatial analysis applied to the archaeological landscape. To this end, a research project was undertaken in order to get a final predictive model for detecting archaeological presence in an area of the Pisa coastal plain, implemented in a Web-orientated Virtual Reality system. The end-user is able to navigate the model in real-time and observe different thematic layers, such as the distribution of the archaeological sites, maps of lithology, land use and, finally, the assessment of the archaeological risk.

  10. Performance of grid-tied PV facilities: A case study based on real data

    International Nuclear Information System (INIS)

    Highlights: • A new procedure to analyse the performance of PV facilities is presented. • It only requires limited amounts of data that are easily sourced. • Data sets on production were collected over two complete years. • The transformerless inverter outperforms the isolated inverter. - Abstract: A new procedure is presented to analyse the performance of grid-tied PV facilities. It needs limited amounts of data that are easily sourced and is based on knowledge of the analysed system and its mode of operation. The procedure is applied, in a case study, to compare real PV production at two 100 kWp grid-connected PV installations. Located in the same geographical region, the installation of these two facilities followed the same construction criteria – PV panels, panel support system and wiring – and the facilities were exposed to the same atmospheric temperature and solar radiation. They differ with regard to their inverter technology: one facility uses an inverter with an integrated transformer system and the other uses a transformerless inverter. The results show that the transformerless inverter system performed better than the isolated system by a factor of 1.2%, which, in economic terms, represents more than 2000 €/year

  11. Leveraging Lean in construction: A case study of a BIM-based HVAC manufacturing process

    Directory of Open Access Journals (Sweden)

    Colin J. Conway

    2014-12-01

    Full Text Available The impetus towards efficiency in the AECO (Architecture, Engineering, Construction & Operations sector is driving the implementation of Lean practices. BIM technologies and BIM processes provide methods by which this can be achieved. Major clients of building services contractors have begun to mandate the use of BIM and some are using BIM preparedness/experience as pre-tender qualification criteria. In this case study, an initial review has been conducted of the achievements of a major Irish M&E contractor in implementing BIM. The firm purpose-built a facility for the off-site manufacture of building services components. The operations of the plant are efficient and quality assured through the use of an appropriately skilled workforce at all stages of manufacture, and tracking software that has developed as the knowledge of the contractor grew. Standardised processes have been developed which have resulted in greater efficiencies and lower costs for the contractor as a result of fewer requirements for onsite modifications (such as those caused by clashes, less waste, and greater flexibility. Despite some initial objections, the employees of the company are now more satisfied with their working conditions and are, as a result, more productive. Through investment in BIM-based, Lean processes, the contractor can now better compete when tendering for large-scale projects in Ireland and worldwide, including the rapidly-increasing number where BIM experience and preparedness is mandated.

  12. Corporate Governance. Case Studies

    OpenAIRE

    Manuel, Eduardo

    2007-01-01

    This paper pretends to do a theoretical approach of Corporate Governance, having as support some case studies about companies like Coca-Cola, Nokia, Microsoft, and Amazon.com. The methodology adopted for this work is based in information from these companies available in their websites and annual reports. I concluded that both companies show the corporate governance components according to their core business and their environmental business.

  13. Institutionalizing evidence-based practice: an organizational case study using a model of strategic change

    Directory of Open Access Journals (Sweden)

    Schultz Alyce A

    2009-11-01

    Full Text Available Abstract Background There is a general expectation within healthcare that organizations should use evidence-based practice (EBP as an approach to improving the quality of care. However, challenges exist regarding how to make EBP a reality, particularly at an organizational level and as a routine, sustained aspect of professional practice. Methods A mixed method explanatory case study was conducted to study context; i.e., in terms of the presence or absence of multiple, inter-related contextual elements and associated strategic approaches required for integrated, routine use of EBP ('institutionalization'. The Pettigrew et al. Content, Context, and Process model was used as the theoretical framework. Two sites in the US were purposively sampled to provide contrasting cases: i.e., a 'role model' site, widely recognized as demonstrating capacity to successfully implement and sustain EBP to a greater degree than others; and a 'beginner' site, self-perceived as early in the journey towards institutionalization. Results The two sites were clearly different in terms of their organizational context, level of EBP activity, and degree of institutionalization. For example, the role model site had a pervasive, integrated presence of EBP versus a sporadic, isolated presence in the beginner site. Within the inner context of the role model site, there was also a combination of the Pettigrew and colleagues' receptive elements that, together, appeared to enhance its ability to effectively implement EBP-related change at multiple levels. In contrast, the beginner site, which had been involved for a few years in EBP-related efforts, had primarily non-receptive conditions in several contextual elements and a fairly low overall level of EBP receptivity. The beginner site thus appeared, at the time of data collection, to lack an integrated context to either support or facilitate the institutionalization of EBP. Conclusion Our findings provide evidence of some of the

  14. Habitat-Lite: A GSC case study based on free text terms for environmental metadata

    Energy Technology Data Exchange (ETDEWEB)

    Kyrpides, Nikos; Hirschman, Lynette; Clark, Cheryl; Cohen, K. Bretonnel; Mardis, Scott; Luciano, Joanne; Kottmann, Renzo; Cole, James; Markowitz, Victor; Kyrpides, Nikos; Field, Dawn

    2008-04-01

    There is an urgent need to capture metadata on the rapidly growing number of genomic, metagenomic and related sequences, such as 16S ribosomal genes. This need is a major focus within the Genomic Standards Consortium (GSC), and Habitat is a key metadata descriptor in the proposed 'Minimum Information about a Genome Sequence' (MIGS) specification. The goal of the work described here is to provide a light-weight, easy-to-use (small) set of terms ('Habitat-Lite') that captures high-level information about habitat while preserving a mapping to the recently launched Environment Ontology (EnvO). Our motivation for building Habitat-Lite is to meet the needs of multiple users, such as annotators curating these data, database providers hosting the data, and biologists and bioinformaticians alike who need to search and employ such data in comparative analyses. Here, we report a case study based on semi-automated identification of terms from GenBank and GOLD. We estimate that the terms in the initial version of Habitat-Lite would provide useful labels for over 60% of the kinds of information found in the GenBank isolation-source field, and around 85% of the terms in the GOLD habitat field. We present a revised version of Habitat-Lite and invite the community's feedback on its further development in order to provide a minimum list of terms to capture high-level habitat information and to provide classification bins needed for future studies.

  15. Pesticide exposure and risk of Parkinson's disease: A family-based case-control study

    Directory of Open Access Journals (Sweden)

    Scott Burton L

    2008-03-01

    Full Text Available Abstract Background Pesticides and correlated lifestyle factors (e.g., exposure to well-water and farming are repeatedly reported risk factors for Parkinson's disease (PD, but few family-based studies have examined these relationships. Methods Using 319 cases and 296 relative and other controls, associations of direct pesticide application, well-water consumption, and farming residences/occupations with PD were examined using generalized estimating equations while controlling for age-at-examination, sex, cigarette smoking, and caffeine consumption. Results Overall, individuals with PD were significantly more likely to report direct pesticide application than their unaffected relatives (odds ratio = 1.61; 95% confidence interval, 1.13–2.29. Frequency, duration, and cumulative exposure were also significantly associated with PD in a dose-response pattern (p ≤ 0.013. Associations of direct pesticide application did not vary by sex but were modified by family history of PD, as significant associations were restricted to individuals with no family history. When classifying pesticides by functional type, both insecticides and herbicides were found to significantly increase risk of PD. Two specific insecticide classes, organochlorines and organophosphorus compounds, were significantly associated with PD. Consuming well-water and living/working on a farm were not associated with PD. Conclusion These data corroborate positive associations of broadly defined pesticide exposure with PD in families, particularly for sporadic PD. These data also implicate a few specific classes of pesticides in PD and thus emphasize the need to consider a more narrow definition of pesticides in future studies.

  16. A case study in the participatory design of a collaborative science-based learning environment

    Science.gov (United States)

    Chin, George, Jr.

    Educational technology research studies have found computer and software technologies to be underutilized in U.S. classrooms. In general, many teachers have had difficulty integrating computer and software technologies into learning activities and classroom curriculums because specific technologies are ill-suited to their needs, or they lack the ability to make effective use of these technologies. In the development of commercial and business applications, participatory design approaches have been applied to facilitate the direct participation of users in system analysis and design. Among the benefits of participatory design include mutual learning between users and developers, envisionment of software products and their use contexts, empowerment of users in analysis and design, grounding of design in the practices of users, and growth of users as designers and champions of technology. In the context of educational technology development, these similar consequences of participatory design may lead to more appropriate and effective education systems as well as greater capacities by teachers to apply and integrate educational systems into their teaching and classroom practices. We present a case study of a participatory design project that took place over a period of two and one half years, and in which teachers and developers engaged in the participatory analysis and design of a collaborative science learning environment. A significant aspect of the project was the development methodology we followed---Progressive Design. Progressive Design evolved as an integration of methods for participatory design, ethnography, and scenario-based design. In this dissertation, we describe the Progressive Design approach, how it was used, and its specific impacts and effects on the development of educational systems and the social and cognitive growth of teachers.

  17. Pro Poor and Community Based Tourism: Case Study of an Investigation into PPT and CBT in Les Village, Bali

    OpenAIRE

    weigall, vanessa

    2013-01-01

    This paper presents the case study of an attempt to introduce tourism as a tool to alleviate poverty in a Balinese village. Despite a positive feasibility study in 2011, tourism has failed to develop. The case study describes the series of events which occurred before, during and after the feasibility study. It then reviews these events in light of themes uncovered during an extensive literature review of Pro-poor and Community-Based Tourism. The study concludes that that the failure to imp...

  18. MIDAS case studies

    Energy Technology Data Exchange (ETDEWEB)

    Brusger, E.C.; Farber, M.A.; Sharpe Hayes, M.M.

    1989-07-01

    This series of three case studies illustrates the validity and usefulness of MIDAS, a microcomputer-based tool for integrated resource planning under uncertainty. The first, at Union Electric, serves to test and validate the model and to illustrate its use for demand/supply option evaluation. Focusing on nuclear plant life extension, the Virginia Power case demonstrates the model's extensive detail, particularly in the production cost and financial areas, as well as its flexibility in addressing approximately 70 uncertainty scenarios. Puget Sound Power Light, the third case, used MIDAS for the preparation of its integrated resource plan. A 108-endpoint decision tree illustrates the full power of the decision analysis capability.

  19. Practicing Sustainability in an Urban University: A Case Study of a Behavior Based Energy Conservation Project

    Science.gov (United States)

    Chan, Stuart; Dolderman, Dan; Savan, Beth; Wakefield, Sarah

    2012-01-01

    This case study of the University of Toronto Sustainability Office's energy conservation project, Rewire, explores the implementation of a social marketing campaign that encourages energy efficient behavior. Energy conservation activities have reached approximately 3,000 students and staff members annually, and have saved electricity, thermal…

  20. Rethinking Sport Teaching in Physical Education: A Case Study of Research Based Innovation in Teacher Education

    Science.gov (United States)

    Pill, Shane; Penney, Dawn; Swabey, Karen

    2012-01-01

    This paper focuses on the significance of physical education teacher education (PETE) in the diffusion of "new" thinking about sport teaching in physical education. It explores issues arising from a case study investigation that sought to respond to the critical commentary about the form and substance of sport teaching in physical education by…

  1. Mind the Gap: A Case Study of Values-Based Decision Making in a Nonprofit Organization

    Science.gov (United States)

    Craft, Jana L.

    2013-01-01

    Using an exploratory case study approach, this research examined the consistency between espoused and enacted values within a large nonprofit organization known as an ethical leader in the human services industry. This research explored ethical business culture, ethical decision making, deontological and utilitarian moral paradigms and learning…

  2. A Case Study of Two Regional State Universities Qualifying as Learning Organizations Based on Administration and Staff Viewpoints

    Science.gov (United States)

    Rich, Tammy Morrison

    2011-01-01

    This case study of 2 state universities qualifying as learning organizations, based on administration and staff viewpoints, was completed using a qualitative methodology. The idea of what a learning organization is can be different depending on who or what is being analyzed. For this study, the work of theorists including W. Edwards Deming,…

  3. Comparing the Principle-Based SBH Maieutic Method to Traditional Case Study Methods of Teaching Media Ethics

    Science.gov (United States)

    Grant, Thomas A.

    2012-01-01

    This quasi-experimental study at a Northwest university compared two methods of teaching media ethics, a class taught with the principle-based SBH Maieutic Method (n = 25) and a class taught with a traditional case study method (n = 27), with a control group (n = 21) that received no ethics training. Following a 16-week intervention, a one-way…

  4. Academic English Teaching for Postgraduates Based on Self-Regulated Learning Environment: A Case Study of Academic Reading Course

    Science.gov (United States)

    Zhao, Wei

    2016-01-01

    This study selects postgraduate students in the first grade as the participants, based on their needs analysis, classroom presentations and performance of assignments completion, through the methodology of case study, the results show that students at the university level even the graduate levels still struggle with academic English. Thus, this…

  5. EXPLAINING THE AUDIT RISK AND ITS COMPONENTS: A COMPARATIVE CASE-STUDY BASED ON AUDIT REPORTS

    Directory of Open Access Journals (Sweden)

    ALINA VOICULESCU

    2014-08-01

    Full Text Available The players activating in the post-recession business environment have to and begin to be more and more prudent and attentive to any sign of human errors, uncertainty, lack of objectivity, attempt of fraud which may occur when financial statements are prepared, in their own case or in the case of their trade clients/suppliers, debtors, business partners, in general. Auditors thus became the mediators between the producers and the users of accountant information, using their high theoretical training, authority, competence and independence as pledge for the fairness of the financial statements and for the compliance with the Law. But even their reports are subject to uncertainty, therefore the author considered useful to approach in the current paper the issue of risk in financial audit, by use of a study-case of several audit reports, in order to explain and exemplify it and to highlight the difference between its components’ evaluation.

  6. The relation between amyotrophic lateral sclerosis and inorganic selenium in drinking water: a population-based case-control study

    OpenAIRE

    Rothman Kenneth J; Bonvicini Francesca; Vinceti Marco; Vescovi Luciano; Wang Feiyue

    2010-01-01

    Abstract Background A community in northern Italy was previously reported to have an excess incidence of amyotrophic lateral sclerosis among residents exposed to high levels of inorganic selenium in their drinking water. Methods To assess the extent to which such association persisted in the decade following its initial observation, we conducted a population-based case-control study encompassing forty-one newly-diagnosed cases of amyotrophic lateral sclerosis and eighty-two age- and sex-match...

  7. Phytoestrogen consumption from foods and supplements and epithelial ovarian cancer risk: a population-based case control study

    OpenAIRE

    Paddock Lisa E; Chandran Urmila; King Melony; Bandera Elisa V; Rodriguez-Rodriguez Lorna; Olson Sara H

    2011-01-01

    Abstract Background While there is extensive literature evaluating the impact of phytoestrogen consumption on breast cancer risk, its role on ovarian cancer has received little attention. Methods We conducted a population-based case-control study to evaluate phytoestrogen intake from foods and supplements and epithelial ovarian cancer risk. Cases were identified in six counties in New Jersey through the New Jersey State Cancer Registry. Controls were identified by random digit dialing, CMS (C...

  8. The implementation of mentalization-based treatment for adolescents: a case study from an organizational, team and therapist perspective

    OpenAIRE

    Hutsebaut Joost; Bales Dawn L; Busschbach Jan JV; Verheul Roel

    2012-01-01

    Abstract Background Reports on problems encountered in the implementation of complex interventions are scarce in psychotherapy literature. This is remarkable given the inherent difficulties of such enterprises and the associated safety risks for patients involved. Case description A case study of the problematic implementation process of Mentalization- Based Treatment for Adolescents (MBT-A), a new therapy for 14 to 18 year old youngsters with severe personality disorders, is presented. The i...

  9. Childhood leukemia and parental occupation: a register-based case-control study

    Energy Technology Data Exchange (ETDEWEB)

    Van Steensel-Moll, H.A.; Valkenburg, H.A.; Van Zanen, G.E.

    1985-02-01

    To explore possible etiologic factors of childhood leukemia, a case-control study was performed in the Netherlands. Cases were selected from a complete nationwide register of cases of childhood leukemia which were diagnosed between 1973 and 1980. Controls were matched with cases for year of birth, sex, and place of residence at the time of diagnosis. Information about possible exposure was collected by a postal questionnaire addressed to the parents. This report concerns the results of the analysis of parental occupations and occupational exposures for 519 children with acute lymphocytic leukemia and 507 controls. During pregnancy, more mothers of patients were working in ''hydrocarbon-related'' occupations; relative risk (RR) = 2.5 (95% confidence interval (CI) = 0.7 - 9.4). Likewise, greater occupational exposure to chemicals (paint, petroleum products, and unspecified chemicals) during pregnancy was found for mothers of patients (RR = 2.4, 95% CI = 1.2 - 4.6). The kind of work being performed by the mothers one year before diagnosis did not differ between cases and controls. For the fathers, no relationship was found between a hydrocarbon-related occupation or occupational exposure to chemicals and leukemia in the offspring. Adjustment for birth order, social class, and degree of urbanization did not materially change the relative risks. 16 references, 5 tables.

  10. [Ecological compensation based on farmers' willingness: A case study of Jingsan County in Hubei Province, China].

    Science.gov (United States)

    Yu, Liang-liang; Cai, Yin-ying

    2015-01-01

    Farmland protection is a pressing issue in China' s major agricultural regions because of the strategic importance of these regions for national food security. This study quantified the appropriate ecological compensation criteria for farmland protection by way of estimating farmers' opportunity cost and willingness to adopt environment-friendly farming practices. Based on survey data collected from Jingsan County, Hubei Province, a Tobit model was constructed to identify factors affecting farmers' willingness to accept (WTA). The result showed that with appropriate economic compensation for farmland protection, 77.1% and 64.7% of the surveyed households were willing to reduce usage of fertilizers and pesticides. When the reduced rates of fertilizer and pesticide increased from 50%, farmers' opportunity costs of production respectively increased from 1198 and 5850 yuan to 9698 and 9750 yuan per hectare per year, and their WTA increased from 4750 and 7313 yuan to 9781 and 12393 yuan per hectare per year. Farmers' opportunity cost and WTA in reducing pesticide inputs were larger than those in reducing the same rate of fertilizer inputs, and in each case farmers' WTA was greater than their opportunity cost. A farm' s distance from township, farmers' knowledge about the ecology of farmland, and their expectation to improve the ecological environment of farmland had positive, significant effect on the farmers' WTA to reducing fertilization, while farmers' education level and the overall economic condition of the village had significantly negative effect. The proportion of agriculture income, farmers' knowledge about the ecology of farmland, and their expectation to improve the ecological environment of farmland had positive, significant effect on the farmers' WTA to reducing pesticide, while household' cash income and the overall economic condition of the village had significantly negative effect. PMID:25985673

  11. UNDERSTANDING THE APPLICABILITY OF LINEAR & NON-LINEAR MODELS USING A CASE-BASED STUDY

    Directory of Open Access Journals (Sweden)

    Gaurav Singh Thakur

    2014-11-01

    Full Text Available This paper uses a case based study – “product sales estimation” on real-time data to help us understand the applicability of linear and non-linear models in machine learning and data mining. A systematic approach has been used here to address the given problem statement of sales estimation for a particular set of products in multiple categories by applying both linear and non-linear machine learning techniques on a data set of selected features from the original data set. Feature selection is a process that reduces the dimensionality of the data set by excluding those features which contribute minimal to the prediction of the dependent variable. The next step in this process is training the model that is done using multiple techniques from linear & non-linear domains, one of the best ones in their respective areas. Data Remodeling has then been done to extract new features from the data set by changing the structure of the dataset & the performance of the models is checked again. Data Remodeling often plays a very crucial and important role in boosting classifier accuracies by changing the properties of the given dataset. We then try to explore and analyze the various reasons due to which one model performs better than the other & hence try and develop an understanding about the applicability of linear & non-linear machine learning models. The target mentioned above being our primary goal, we also aim to find the classifier with the best possible accuracy for product sales estimation in the given scenario.

  12. Childhood asthma in Beijing, China: A population-based case-control study

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, T.Z.; Niu, S.R.; Lu, B.Y.; Fan, X.E.; Sun, F.Y.; Wang, J.P.; Zhang, Y.W.; Zhang, B.; Owens, P.; Hao, L.Y.; Li, Y.D.; Leaderer, B. [Yale School of Medicine, New Haven, CT (United States). Dept. of Epidemiology & Public Health

    2002-11-15

    A population-based case-control study was conducted in Shunyi County, People's Republic of China, in January 1999 and March 2001 to investigate the risk factors for childhood asthma. An increased risk of childhood asthma was associated with smoking by relatives in front of the mother while she was pregnant with the child (odds ratio (OR) = 1.3, 95% confidence interval (CI): 1.0, 1.6) and with smoking by relatives in front of the child (OR = 1.4, 95% CI: 1.1, 1.9). The risk increased with the increasing number of smokers and the total minutes of smoking by relatives in front of both the child and the mother while she was pregnant with the child. An increased risk was observed for use of coal for heating (OR = 1.5, 95% CI: 1.1, 1.9). Those who reported using coal for cooking without ventilation also had an increased risk (OR = 2.3, 95% CI: 1.5, 3.5). An increased risk was observed for those who reported having molds or fungi on the ceilings of their houses (OR = 1.8, 95% CI: 1.1, 2.9) or inside the child's room (OR 1.8, 95% CI: 1.0, 3.2). An increased risk was also found for those having both a dog and a cat as pets (OR 1.5, 95% CI: 1.0, 2.3) or for finding both cockroaches and rats inside their houses (OR = 1.8, 95% CI: 1.2, 2.8).

  13. The student tutor experience in a problem-based learning course: A case study

    Science.gov (United States)

    Moore, Tricia Susan

    This case study, conducted from an interpretive paradigm, illuminates contextual factors related to the tutor experience when senior undergraduate dental hygiene students served as tutors for beginning undergraduate dental hygiene students, or sophomores, in a 1-semester, 2-hour long problem-based learning (PBL) course in a Baccalaureate Dental Hygiene (BDH) curriculum during the spring semester of 2008. Data were collected using various sources and methods. Six tutors and three administrators were interviewed, tutees completed an anonymous questionnaire, the tutorial process and tutor training sessions were observed, and related documents were examined. Data analysis included open and axial coding, creation of tutor profiles, and identification of patterns. Tutor behaviors varied with respect to the nature of intervention (e.g., telling, asking, clarifying, acknowledging), emphasis (process, content, social), and facilitation style (directive, suggestive, empowering). Patterns in tutor behavior and attitudes emerged related to comfort and growth, persistence and lenience, and compliance, resistance, and innovation. Differences in tutor understanding and perception of their role and the purpose of PBL influenced the role the tutor assumed. Other factors that influenced tutor behavior included tutor intentions, tutor training, and environmental factors such as the nature of problems, allotted time, and tutorial group characteristics. The influence of these factors can be understood by applying Fishbein's integrated model of behavior prediction (Fishbein, 2008). Tutor training included experiencing the PBL student role, attending class, and sharing experiences with other tutors in weekly seminar sessions facilitated by a tutor supervisor. Tutor's gained confidence, knowledge, skills, and friendship. They also had the opportunity to see things from a new perspective, that of a teacher encouraging self-direction rather than a student depending on others for direction

  14. INTERNAL GOVERNANCE AND ROLE OF INTERNAL AUDIT IN FINANCIAL INSTITUTIONS. CASE STUDY: RISK BASED PLANNING

    Directory of Open Access Journals (Sweden)

    Andrei Florin

    2015-07-01

    Full Text Available The global financial crisis from 2008 was considered a trigger to reshape the financial systems and to enhance the risk management practices. Considering the developments and new guidelines that are now used it can be observed a “positive” effect of the crisis, in particular to strengthen the risk management culture and governance in all aspects. Comparing to 2008 year, the improvements that have been made to the risk management systems can be easily observed in the financial institutions. For the scope of the article, the subject of this review will be focused on the internal audit function. The main aspect is to capture the new practices that are now used in order to contribute to a performing internal governance system. A case study will be presented in order to better understand how the internal audit function is designed and acting as a “line” of defence in the internal governance system. Also, it is in the scope of the article to issue some recommendations for future developments of the audit function in order to better manage its mission and the objectives. A risk based model used in the planning activities is presented. The financial institutions improved significantly their internal governance system. The internal audit function is now better integrated in the internal structures and clear lines of communication were settled. As the conclusion of the article is illustrating, the internal governance was frequently not sufficiently developed causing a failure in the risk management systems from the systemically financial institutions. The content of the article has practical applicability, as the results and the recommendations could be used in the design of an audit function within a financial institution.

  15. An approach to model validation and model-based prediction -- polyurethane foam case study.

    Energy Technology Data Exchange (ETDEWEB)

    Dowding, Kevin J.; Rutherford, Brian Milne

    2003-07-01

    Enhanced software methodology and improved computing hardware have advanced the state of simulation technology to a point where large physics-based codes can be a major contributor in many systems analyses. This shift toward the use of computational methods has brought with it new research challenges in a number of areas including characterization of uncertainty, model validation, and the analysis of computer output. It is these challenges that have motivated the work described in this report. Approaches to and methods for model validation and (model-based) prediction have been developed recently in the engineering, mathematics and statistical literatures. In this report we have provided a fairly detailed account of one approach to model validation and prediction applied to an analysis investigating thermal decomposition of polyurethane foam. A model simulates the evolution of the foam in a high temperature environment as it transforms from a solid to a gas phase. The available modeling and experimental results serve as data for a case study focusing our model validation and prediction developmental efforts on this specific thermal application. We discuss several elements of the ''philosophy'' behind the validation and prediction approach: (1) We view the validation process as an activity applying to the use of a specific computational model for a specific application. We do acknowledge, however, that an important part of the overall development of a computational simulation initiative is the feedback provided to model developers and analysts associated with the application. (2) We utilize information obtained for the calibration of model parameters to estimate the parameters and quantify uncertainty in the estimates. We rely, however, on validation data (or data from similar analyses) to measure the variability that contributes to the uncertainty in predictions for specific systems or units (unit-to-unit variability). (3) We perform statistical

  16. LIFE CYCLE ASSESSMENT FOR OIL PALM BASED PLYWOOD: A GATE-TO-GATE CASE STUDY

    OpenAIRE

    M. Shamim Ahmad; Vijaya Subramaniam; Halimah Mohammad; Anis Mokhtar; Ismail, B. S.

    2014-01-01

    Life Cycle Assessment (LCA) is an important tool for identifying potential environmental impacts associated with the production of palm based plywood. This study is to make available the life cycle inventory for gate-to-gate data so that the environmental impact posed by oil palm based plywood production can be assessed. Conducting an LCA on the palm based plywood that are derived from the wastes of the oil palm industry is a first step towards performing green environmental product. Therefor...

  17. Linking activity-based travel demand models and traffic assignment: A Flemish case study

    OpenAIRE

    Ramaekers, Katrien; Kochan, Bruno; BELLEMANS, Tom; JANSSENS, Davy; Wets, Geert

    2008-01-01

    A custom agent-based simulation framework is developed that combines the fields of traffic demand modeling and traffic assignment, applied to the region of Flanders (Belgium). The framework uses an activity-based approach to model traffic demand and an assignment module that is linked to the traffic demand module. Activity data for the framework is provided by a large scale survey, conducted on 2500 households in the study area. The agent-based simulation model consists of over six million ag...

  18. TEFL Training Program for Local and Cultural-based Instruction: Case Studies in Thai Primary Schools

    OpenAIRE

    Sasiwan Potcharapanpong; Sumlee Thongthew

    2010-01-01

    The main purpose of this study is to develop an EFL Training Program based on the combination of three theories: reflective teaching, brain-based learning, and school-based training. The program was voluntarily applied by ten elementary teachers from Surin province, Thailand. The program included competency assessment, EFL competency enhancement, EFL teaching activities development and practices, and program evaluation. The activity created positive impacts to the EFL teaching particularly st...

  19. [Analysis suspected allergic factors to shenqi fuzheng injection based on prescription sequence analysis and nested case control study].

    Science.gov (United States)

    Ai, Qing-Hua; Zeng, Xian-Bin; Xie, Yan-Ming; Yang, Wei

    2014-09-01

    This study based on twenty 3A grade hospital information system (HIS) database in China, adopt toprescription sequence analysis (PSA) with nested case control study (NCCS) to analysis mainly suspected allergy factor of Shenqi Fuzheng injection (Shenqi Fuzheng). Study design according to start to stop using Shenqi Fuzheng whether using dexamethasone injection will crowd divided into cases group and control group, each case matched 4 controls were selected, two groups according to the ratio of the age and sex matched well. Square test, Fisher exact test, single factor and multiple factor logistic regression were used to analyze data Condition on admission, allergic history, dosage and drug combinations were taken into account in cases of suspected allergic reactions. After analysis in two subgroups we found that the single dose (P = 0.000 2) and the combined use of matrine (P marketing Chinese medicine injection. PMID:25532396

  20. Report on decision-making of geological disposal. Discussion based on case study

    International Nuclear Information System (INIS)

    History of geological disposal from 1950 to 2000 in the world and some examples of change of policy in France, Sweden and Canada are explained. On the case study of three countries, investigations of background of the change, site decision process, communication, flexible concept of disposal are stated. Japan decided the high level radioactive waste is disposed in underground (300m deeper) under the Law Concerning the Final Disposal of Special Radioactive Waste in June, 2000. NUMO (Nuclear Waste Management Organization of Japan) was established to manage disposal of radioactive waste in October, 2000. NUMO started to accept application for the site of disposal in the country in December, 2002. The above case study is a good guide to promote geological disposal of radioactive waste. (S.Y.)

  1. Can Interactive Web-Based CAD Tools Improve the Learning of Engineering Drawing? A Case Study

    Science.gov (United States)

    Pando Cerra, Pablo; Suárez González, Jesús M.; Busto Parra, Bernardo; Rodríguez Ortiz, Diana; Álvarez Peñín, Pedro I.

    2014-01-01

    Many current Web-based learning environments facilitate the theoretical teaching of a subject but this may not be sufficient for those disciplines that require a significant use of graphic mechanisms to resolve problems. This research study looks at the use of an environment that can help students learn engineering drawing with Web-based CAD…

  2. Evaluation Criteria for Competency-Based Syllabi: A Chilean Case Study Applying Mixed Methods

    Science.gov (United States)

    Jerez, Oscar; Valenzuela, Leslier; Pizarro, Veronica; Hasbun, Beatriz; Valenzuela, Gabriela; Orsini, Cesar

    2016-01-01

    In recent decades, higher education institutions worldwide have been moving from knowledge-based to competence-based curricula. One of the greatest challenges in this transition is the difficulty in changing the knowledge-oriented practices of teachers. This study evaluates the consistency between syllabus design and the requirements imposed by a…

  3. Energy saving in smart homes based on consumer behaviour: A case study

    OpenAIRE

    Zehnder, Michael; Wache, Holger; Witschel, Hans-Friedrich; Zanatta, Danilo; Rodriguez, Miguel

    2015-01-01

    This paper presents a case study of a recommender system that can be used to save energy in smart homes without lowering the comfort of the inhabitants. We present an algorithm that uses consumer behavior data only and uses machine learning to suggest actions for inhabitants to reduce the energy consumption of their homes. The system mines for frequent and periodic patterns in the event data provided by the Digitalstrom home automation system. These patterns are converted into association rul...

  4. Virtual RTCP: A Case Study of Monitoring and Repair for UDP-based IPTV Systems

    OpenAIRE

    Soni García, A.; Ott, J; Ellis, M; Perkins, C.(University of California, Berkeley, CA, 94720, USA)

    2012-01-01

    IPTV systems have seen widespread deployment, but often lack robust mechanisms for monitoring the quality of experience. This makes it difficult for network operators to ensure that their services match the quality of traditional broadcast TV systems, leading to consumer dissatisfaction. We present a case study of virtual RTCP, a new framework for reception quality monitoring and reporting for UDP-encapsulated MPEG video delivered over IP multicast. We show that this allows incremental deploy...

  5. Invasive fungal disease in university hospital: a PCR-based study of autopsy cases

    OpenAIRE

    Ruangritchankul, Komkrit; Chindamporn, Ariya; Worasilchai, Navaporn; Poumsuk, Ubon; Keelawat, Somboon; Bychkov, Andrey.

    2015-01-01

    Invasive fungal disease (IFD) has high mortality rate, especially in the growing population of immunocompromised patients. In spite of introduction of novel diagnostic approaches, the intravital recognition of IFD is challenging. Autopsy studies remain a key tool for assessment of epidemiology of visceral mycoses. We aimed to determine species distribution and trends of IFD over the last 10 years in unselected autopsy series from a large university hospital. Forty-five cases of visceral mycos...

  6. Stem Cell Based Regenerative Medicine: Is Russia Taking the Lead? A Case Study from St. Petersburg

    OpenAIRE

    Iryna Palona; Jokull Johannesson

    2010-01-01

    The recent scientific breakthroughs in genetics have lead to a thriving stem cell industry transforming the way medicine is practiced. This article discusses these developments and presents a case study of Russian research institute in St. Petersburg which is doing state of the art stem cell trials providing successful treatment of blood vessel disease andbone fractures. The potential impact of stem cell technology on regenerative medicine is discussed, the potential convergence of nanopartic...

  7. Translating evidence-based guidelines to improve feedback practices: the interACT case study

    OpenAIRE

    Barton, Karen L.; Schofield, Susie J.; McAleer, Sean; Ajjawi, Rola

    2016-01-01

    Background There has been a substantial body of research examining feedback practices, yet the assessment and feedback landscape in higher education is described as ‘stubbornly resistant to change’. The aim of this paper is to present a case study demonstrating how an entire programme’s assessment and feedback practices were re-engineered and evaluated in line with evidence from the literature in the interACT (Interaction and Collaboration via Technology) project. Methods Informed by action r...

  8. The Quality of Stakeholder-Based Decisions: Lessons from the Case Study Record

    OpenAIRE

    Beierle, Thomas

    2000-01-01

    The increased use of stakeholder processes in environmental decisionmaking has raised concerns that the inherently “political” nature of such processes may sacrifice substantive quality for political expediency. In particular, there is concern that good science will not be used adequately in stakeholder processes nor be reflected in their decision outcomes. This paper looks to the case study record to examine the quality of the outcomes of stakeholder efforts and the scientific and technical ...

  9. Metamorphoses of cogeneration-based district heating in Romania: A case study

    International Nuclear Information System (INIS)

    The paper presents the birth and evolution of the cogeneration-based district heating (DH) system in a medium size city in Romania (Targoviste). The evolution of the industrialization degree was the main factor which controlled the population growth and led to a continuous reconfiguration of the DH system. The DH system assisted by cogeneration emerged as a solution in a certain phase of the demographic development of the city. The political and social changes occurring in Romania after 1990 have had important negative consequences on the DH systems in small towns. In Targoviste the DH system survived but in 2001 the solution based on cogeneration became economically inefficient, due to the low technical quality of the existing equipment and the low gas prices, to the procedure of setting the DH tariffs and the service cost at consumer's level and to some bureaucratic problems. Energy policy measures taken at national and local levels in 2003 and 2005 led to the re-establishment of the cogeneration-based district heating in 2005. However, a different technical solution has been adopted. Details about the present (2009) cogeneration-based DH system in Targoviste are presented together with several technical and economical indicators. The main conclusion is that by a proper amendment of the technical solutions, cogeneration could be a viable solution for DH even in case of abrupt social and demographic changes, such as those occurring in Romania after 1990. - Research Highlights: →Birth and evolution of the cogeneration-based district heating system in a medium size city. →The industrialization degree is the main factor which controlled the reconfiguration of the district heating system. →Each stage of the evolution of district heating system has been a technological leap. →Cogeneration is a solution for district heating even in case of abrupt social changes.

  10. Streamline-based Simulation of Geological CO2 Storage: Otway Case-Study

    Science.gov (United States)

    Lazaro Vallejo, Lorena; Dance, Tess; Cinar, Yildiray; Laforce, Tara

    2010-05-01

    Three of the most important challenges for the near future: maximizing oil extraction, securing fresh water supplies and mitigating climate change through Carbon Capture and Storage (CCS), require a better understanding of flow in porous media. It has been shown by Qi et al [1] that an optimum injection strategy for CO2 storage can result in up to 90% of the injected CO2 being trapped in the pore network of the rock during the injection phase of a CO2 storage project. When the non-wetting phase saturation increases and then decreases in the pore space, part of the non-wetting phase is trapped in pores as a residual saturation. Injection of CO2 and water in alternating cycles can be used to engineer this trapping. With time, CO2 will dissolve in the brine surrounding it and finally precipitate as carbonate. The Otway Project, taking place in the south-east of Australia and lead by the Cooperative Research Centre for Greenhouse Gas Technologies (CO2CRC), is the world's largest research and geosequestration demonstration project [2]. CO2CRC has proposed testing the concept of using residual trapping to improve storage security by using Huff and Push injections. In this case, CO2 is injected in a depleted gas reservoir together with methane. The Huff and Push injection mechanism consists of a single well which alternates injection and production. Initially, brine is injected followed by a mixture of CO2/CH4/other gases (77/20/3 mole%) followed by a shut-in period. Then, when production starts the water front should move faster towards the production well and immobilise CO2 in the micro pores of the rock. Very little production of CO2 should be observed, confirming that it has been immobilized within the formation. Traditional grid-based reservoir simulations are used to predict fluid behaviour and to design injection strategies that maximize both oil extraction and trapping of carbon dioxide in the rock formation. Unlike conventional grid-based simulations, streamline-based

  11. Determinants of mortality from severe dengue in Brazil: a population-based case-control study.

    Science.gov (United States)

    Moraes, Giselle Hentzy; de Fátima Duarte, Eliane; Duarte, Elisabeth Carmen

    2013-04-01

    Although increases in severity of mortality from dengue infection have been observed in Brazil, their determinants are not fully known. A case-control study was conducted by using the National Notifiable Diseases Surveillance System, including patients with severe dengue during 2000-2005. Cases were defined as patients that died and controls were those who survived. Hierarchical multivariate logistic regression was performed. During the study period, there were 12,321 severe cases of dengue and 1,062 deaths. Factors independently associated with death included age ≥ 50 years (odds ratio [OR] = 2.29, 95% confidence interval [CI] = 1.59-3.29), history of previous dengue (OR = 0.78, 95% CI = 0.62-0.99), positive tourniquet test result (OR = 0.47, 95% CI = 0.33-0.66), laboratory diagnosis of dengue (OR = 0.75, 95% CI = 0.61-0.92), and a platelet count of 50,000-100,000 cells/mm(3) (OR = 0.56, 95% CI = 0.36-0.87). The risk profile identified in this study should serve to direct public health interventions to minimize deaths. PMID:23400577

  12. Energy Provider: Delivered Energy Efficiency: A global stock-taking based on case studies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-01

    In 2011 the IEA and the Regulatory Assistance Project (RAP) took on a work programme focused on the role of energy providers in delivering energy efficiency to end-users. This work was part of the IEA’s contribution to the PEPDEE Task Group, which falls under the umbrella of the International Partnership on Energy Efficiency Cooperation (IPEEC). In addition to organizing regional dialogues between governments, regulators, and energy providers, the PEPDEE work stream conducted global stock-takings of regulatory mechanisms adopted by governments to obligate or encourage energy providers to delivery energy savings and the energy savings activities of energy providers. For its part the IEA conducted a global review of energy provider-delivered energy savings programmes. The IEA reached out to energy providers to identify the energy savings activities they engaged in. Some 250 energy saving activities were considered, and 41 detailed case studies spanning 18 countries were developed. Geographic balance was a major consideration, and much effort was expended identifying energy provider-delivered energy savings case studies from around the world. Taken together these case studies represent over USD 1 billion in annual spending, or about 8% of estimated energy provider spending on energy efficiency.

  13. A MCDM-based model for vendor selection: a case study in the particleboard industry

    Institute of Scientific and Technical Information of China (English)

    Reza Zanjirani Farahani; Moslem Fadaei

    2012-01-01

    We investigated procurement of raw materials for particleboard to minimize costs and develop an efficient optimization model for product mix.In a multiple-vendor market,vendors must be evaluated based on specified criteria.Assuming sourcing from the highest-scoring vendors,annual purchase quantities are then planned.To meet procurement needs,we first propose a model to describe the problem.Then,an appropriate multi-criteria decision making (MCDM) technique is selected to solve it.We ran the model using commercial software such as LINGO(R) and then compared the model results to a real case involving one of the largest particleboard manufacturers in the region.The model mn based real data yielded a procurement program that is more efficient and lower in cost than the program currently in use.Use of this procurement modelling approach would yield considerable financial returns.

  14. The Art of Empathy: A Mixed Methods Case Study of a Critical Place-Based Art Education Program

    Science.gov (United States)

    Bertling, Joy Gaulden

    2012-01-01

    This mixed methods case study examined middle school students' empathy with the environment within a critical place-based art classroom. The curriculum was informed by the ecological imagination, which calls for a new mode of education: education that embraces the arts as a way to conceive of pro-ecological perspectives, other ways of being…

  15. Time-Driven Activity-Based Costing for Inter-Library Services: A Case Study in a University

    Science.gov (United States)

    Pernot, Eli; Roodhooft, Filip; Van den Abbeele, Alexandra

    2007-01-01

    Although the true costs of inter-library loans (ILL) are unknown, universities increasingly rely on them to provide better library services at lower costs. Through a case study, we show how to perform a time-driven activity-based costing analysis of ILL and provide evidence of the benefits of such an analysis.

  16. BladeRunners and Picasso Cafe: A Case Study Evaluation of Two Work-Based Training Programs for Disadvantaged Youth.

    Science.gov (United States)

    Currie, Sheila; Foley, Kelly; Schwartz, Saul; Taylor-Lewis, Musu

    In 1998, Canada's Social Research and Demonstration Corporation (SRDC) conducted case studies of two work-based training and skill development programs for street youth in Vancouver, British Columbia. The BladeRunners program places youth on construction sites while encouraging them to work toward an apprenticeship in the building trades. The…

  17. Training Post-9/11 Police Officers with a Counter-Terrorism Reality-Based Training Model: A Case Study

    Science.gov (United States)

    Biddle, Christopher J.

    2013-01-01

    The purpose of this qualitative holistic multiple-case study was to identify the optimal theoretical approach for a Counter-Terrorism Reality-Based Training (CTRBT) model to train post-9/11 police officers to perform effectively in their counter-terrorism assignments. Post-9/11 police officers assigned to counter-terrorism duties are not trained…

  18. Innovative Asia: Advancing the Knowledge-Based Economy: Country Case Studies for the PRC, India, Indonesia, and Kazakhstan

    OpenAIRE

    Asian Development Bank

    2014-01-01

    This report presents the case studies of the People’s Republic of China, India, Indonesia and Kazakhstan in their knowledge-based economy approaches. It identifies a range of policies and initiatives that these economies need to consider to strengthen innovation led growth and make a transition from middle income to high income levels.

  19. A Case Study on Collective Cognition and Operation in Team-Based Computer Game Design by Middle-School Children

    Science.gov (United States)

    Ke, Fengfeng; Im, Tami

    2014-01-01

    This case study examined team-based computer-game design efforts by children with diverse abilities to explore the nature of their collective design actions and cognitive processes. Ten teams of middle-school children, with a high percentage of minority students, participated in a 6-weeks, computer-assisted math-game-design program. Essential…

  20. Contributions of Early Work-Based Learning: A Case Study of First Year Pharmacy Students

    Science.gov (United States)

    Ting, Kang Nee; Wong, Kok Thong; Thang, Siew Ming

    2009-01-01

    Generally work-based learning opportunities are only offered to students in their penultimate year of undergraduate study. Little is known about the benefits and shortcomings of such experiential learning for students in the early stages of their undergraduate education. This is a mixed method study investigating first year undergraduate pharmacy…

  1. Risk of hospitalization for acute pancreatitis associated with conventional and atypical antipsychotics: a population-based case-control study

    DEFF Research Database (Denmark)

    Gasse, Christiane; Jacobsen, Jacob; Pedersen, Lars;

    2008-01-01

    STUDY OBJECTIVE: To examine the association of atypical and conventional antipsychotics with the risk of hospitalization for acute pancreatitis. DESIGN: Population-based, case-control study. DATA SOURCE: Health care databases of Northern Denmark. PATIENTS: A total of 3083 adults hospitalized with...... acute pancreatitis (case patients) and 30,830 control subjects. MEASUREMENTS AND MAIN RESULTS: Controls were selected from the general population by using risk-set sampling and were matched to case patients by age and sex. The date of the case patients' admission for acute pancreatitis was used as the...... index date for the matched control subjects. Conditional logistic regression analysis was used to estimate rate ratios (RRs) for hospitalization due to acute pancreatitis in current users (0-90 days before admission or index date) and former users (> 90 days before admission or index date) of atypical...

  2. An aircraft-based case study of new particle formation and growth in the summertime Arctic

    Science.gov (United States)

    Willis, M. D.; Abbatt, J.; Burkart, J.; Bozem, H.; Koellner, F.; Schneider, J.; Hoor, P. M.; Herber, A. B.; Leaitch, W. R.

    2015-12-01

    Motivated by the changing climate of the Arctic and decreasing summer sea-ice extent, we aim to better understand how atmospheric composition will impact, or be impacted by, climate and environmental change in this region. Much attention has been paid to springtime Arctic aerosol owing to significant anthropogenic influence on this remote environment, but the cleaner, more locally influenced summertime Arctic is not well characterized. We present results of vertically resolved, particle number, aerosol size distributions, submicron aerosol composition from an aerosol mass spectrometer (AMS), and cloud condensation nuclei (CCN) concentrations from the NETCARE 2014 Polar 6 aircraft campaign. The campaign was based in the high Arctic, at Resolute Bay, Nunavut, Canada (74°N, 94°W), allowing measurements from 60 to 2900 meters over ice, open water and near the ice-edge. The focus of this case study is a new particle formation and growth event observed at the eastern end of Lancaster Sound (74°N, 81°W) on July 12, 2014 under clear sky conditions. During this flight Polar 6 travelled to the end of Lancaster Sound at 2900 m and subsequently descended to 60-70 m above the surface heading due west, with winds from the west. At the lowest altitude we observed a significant increase in particles > 4 nm, between 20 - 100 nm, and > 100 nm, indicating the presence of small particles between 4 - 20 nm and growth to larger sizes. In addition, CCN concentrations were enhanced up to ~ 200/cm3 from background levels of ≤ 100/cm3. Concurrently, the AMS indicated enhanced levels of methane sulfonic acid (MSA) and marine-like organic aerosol (OA) correlated in time with the presence of larger particles, as well as an iodide signal which correlated with the presence of small particles. These observations suggest that iodine oxides could be one contributor to particle formation, and that marine-like OA and MSA could contribute to particle growth in the summertime Arctic.

  3. Motivations, Risks, Barriers, and Results Associated with the Adoption of Global Sourcing by Brazilian Companies: a Case-Based Study

    OpenAIRE

    Moema Pereira Nunes

    2016-01-01

    This article aims to identi fy the motivations behind g lobal s ourcing (GS) adoption , the associated risks and barriers , and the results that companies from emerging countries are achieving . The research explores the distinguishing features of these companies ' experience and examines established theories about GS that are based on companies from developed countries. In the article, a case - based study investigat ed four companies from t...

  4. Academic staff's perceptions of implementing performance-based review system in a tertiary institution : a case study

    OpenAIRE

    Kwok, Nga-man; 郭雅文

    2013-01-01

    Introducing a new performance-based review with 100% support from staff in a well-established university is difficult for the university management. Apart from measuring whether regulations have been followed or not, acceptance of academic staff is one key area that educational organizations should not ignore when evaluating effectiveness of a performance-based policy. Using the case university as an example, this study aims at investigating academic staff’s perceptions of gradually introduci...

  5. Thyroid cancer in French Polynesia: a population based case control study

    Energy Technology Data Exchange (ETDEWEB)

    Brindel, P.; Doyon, F.; Adjadj, E.; Vathaire, F. de [Institut Gustave Roussy, INSERM U605, 94 - Villejuif (France); Drozdovitch, V. [International Agency for Research on Cancer, 69 - Lyon (France); Bouville, A. [DHHS/NIH/NCI/Div. of Cancer Epidemiology and Genetics EPS (United States); Paoaafaite, J.; Teuri, J. [IRD, Papeete Tahiti (France)

    2006-07-01

    Full text of publication follows: Because a previous study had shown that registered thyroid cancer incidence is higher among natives of French Polynesia (FP) than in other Maori populations from Hawaii and New-Zealand, a case-control study of thyroid cancer coordinated by Unit 605 of INSERM was conducted in FP. The main objective was to assess the potential role of atmospheric nuclear weapons tests performed by France between 1966 and 1974 on such a high incidence. The study included 600 subjects born and residing in FP: 229 cases of differentiated thyroid carcinoma diagnosed between 1979 and 2004, aged up to 30 years old at start of nuclear weapons testing and 371 control s matched on gender and birth date randomly selected from the FP registry of births. Face to face interviews were conducted from 2002 to 2004 by specialized investigators native from FP who received a specific formation for this study. Addresses were collected from the territorial medical insurance, which covers all the inhabitants, whatever their professional status. Detailed information about nutrition at time of interview and at the end of adolescence was collected by means of a semi-quantitative method using pictures. Data concerning residence, hormonal and reproductive life, familial and personal background of thyroid pathologies and cancers, and professional and environmental exposure to carcinogens were also collected. For each study subject, radiation thyroid dose was estimated taking into account residential history and dietary habits of the subject and deposition densities of radionuclides reconstructed for each island where the subject resided during the testing period. The iodine intake will be estimated from the dietary questionnaire, as well as from mass-spectrometry measurements of stable iodine in nail clippings, which were collected during the interviews. Among the 229 cases, 89% were females, 54% declared themselves as of pure Maori origin, another 36% of Maori-Asian or Maori

  6. Thyroid cancer in French Polynesia: a population based case control study

    International Nuclear Information System (INIS)

    Full text of publication follows: Because a previous study had shown that registered thyroid cancer incidence is higher among natives of French Polynesia (FP) than in other Maori populations from Hawaii and New-Zealand, a case-control study of thyroid cancer coordinated by Unit 605 of INSERM was conducted in FP. The main objective was to assess the potential role of atmospheric nuclear weapons tests performed by France between 1966 and 1974 on such a high incidence. The study included 600 subjects born and residing in FP: 229 cases of differentiated thyroid carcinoma diagnosed between 1979 and 2004, aged up to 30 years old at start of nuclear weapons testing and 371 control s matched on gender and birth date randomly selected from t he FP registry of births. Face to face interviews were conducted from 2002 to 2004 by specialized investigators native from FP who received a specific formation for this study. Addresses were collected from the territorial medical insurance, which covers all the inhabitants, whatever their professional status. Detailed information about nutrition at time of interview and at the end of adolescence was collected by means of a semi-quantitative method using pictures. Data concerning residence, hormonal and reproductive life, familial and personal background of thyroid pathologies and cancers, and professional and environmental exposure to carcinogens were also collected. For each study subject, radiation thyroid dose was estimated taking into account residential history and dietary habits of the subject and deposition densities of radionuclides reconstructed for each island where the subject resided during the testing period. The iodine intake will be estimated from the dietary questionnaire, as well as from mass-spectrometry measurements of stable iodine in nail clippings, which were collected during the interviews. Among the 229 cases, 89% were females, 54% declared themselves as of pure Maori origin, another 36% of Maori-Asian or Maori

  7. Biopharmaceutics classification system-based biowaivers for generic oncology drug products: case studies.

    Science.gov (United States)

    Tampal, Nilufer; Mandula, Haritha; Zhang, Hongling; Li, Bing V; Nguyen, Hoainhon; Conner, Dale P

    2015-02-01

    Establishing bioequivalence (BE) of drugs indicated to treat cancer poses special challenges. For ethical reasons, often, the studies need to be conducted in cancer patients rather than in healthy volunteers, especially when the drug is cytotoxic. The Biopharmaceutics Classification System (BCS) introduced by Amidon (1) and adopted by the FDA, presents opportunities to avoid conducting the bioequivalence studies in humans. This paper analyzes the application of the BCS approach by the generic pharmaceutical industry and the FDA to oncology drug products. To date, the FDA has granted BCS-based biowaivers for several drug products involving at least four different drug substances, used to treat cancer. Compared to in vivo BE studies, development of data to justify BCS waivers is considered somewhat easier, faster, and more cost effective. However, the FDA experience shows that the approval times for applications containing in vitro studies to support the BCS-based biowaivers are often as long as the applications containing in vivo BE studies, primarily because of inadequate information in the submissions. This paper deliberates some common causes for the delays in the approval of applications requesting BCS-based biowaivers for oncology drug products. Scientific considerations of conducting a non-BCS-based in vivo BE study for generic oncology drug products are also discussed. It is hoped that the information provided in our study would help the applicants to improve the quality of ANDA submissions in the future. PMID:25245330

  8. Using Analysis of Governance to Unpack Community-Based Conservation: A Case Study from Tanzania

    Science.gov (United States)

    Robinson, Lance W.; Makupa, Enock

    2015-11-01

    Community-based conservation policies and programs are often hollow with little real devolution. But to pass a judgment of community-based or not community-based on such initiatives and programs obscures what is actually a suite of attributes. In this paper, we analyze governance around a specific case of what is nominally community-based conservation—Ikona Wildlife Management Area (WMA) in Tanzania—using two complementary sets of criteria. The first relates to governance "powers": planning powers, regulatory powers, spending powers, revenue-generating powers, and the power to enter into agreements. The second set of criteria derive from the understanding of governance as a set of social functions: social coordination, shaping power, setting direction, and building community. The analysis helps to detail ways in which the Tanzanian state through policy and regulations has constrained the potential for Ikona WMA to empower communities and community actors. Although it has some features of community-based conservation, community input into how the governance social functions would be carried out in the WMA was constrained from the start and is now largely out of community hands. The two governance powers that have any significant community-based flavor—spending powers and revenue-generating powers—relate to the WMA's tourism activities, but even here the picture is equivocal at best. The unpacking of governance that we have done, however, reveals that community empowerment through the processes associated with creating and recognizing indigenous and community-conserved areas is something that can be pursued through multiple channels, some of which might be more strategic than others.

  9. Developing an Agent-Based Model to Simulate Urban Land-Use Expansion (Case Study: Qazvin

    Directory of Open Access Journals (Sweden)

    F. Nourian

    2012-01-01

    Full Text Available Extended abstract1-IntroductionUrban land-use expansion is a challenging issue in developing countries. Increases in population as well as the immigration from the villages to the cities are the two major factors for that phenomenon. Those factors have reduced the influence of efforts that try to limit the cities’ boundaries. Thus, spatial planners always look for the models that simulate the expansion of urban land-uses and enable them to prevent unbalanced expansions of cities and guide the developments to the desired areas. Several models have been developed and evaluated for simulating urban land-use expansions. Despite the variety of the models, most of them have focused on simulating urban land-use expansions just around a city. Thus, the regional models that consider wider area are of primary importance.2- Theoretical basesIn this study a new agent-based model has been developed and implemented to simulate urban land-use expansion in Qazvin and Alborz regions of Qazvin state which have an area of 1620 square kilometers. In this model, land-use developers have been treated as agents that move in the landscape explicitly and assess the state of parcels for development. So, the environment of the model is raster. The agents are developed into five groups which have different aims. The agents may fall in competition to develop the same parcels. Moreover, due to the spatial essence of the problem, GIS were used to prepare the environment of agents’ movement and search and to aggregate and analyze the results.Two main steps can be recognized in this model: the Searching step and the Development step:Searching step: The agents are created and distributed in the districts. The selection of districts is probabilistic and is based on the primary probability of selection, assumed for districts. When agents go to the districts, at first they move randomly to the neighborhood of pre-developed areas. Wherever the agent starts its activities, it

  10. A clinicopathologic and immunohistochemical study of gastrointestinal stromal tumors based on 122 cases

    Institute of Scientific and Technical Information of China (English)

    Shanglong Liu; Zifang Song; Wei Li; Xiaowei Liu; Chen Zhang; Qichang Zheng

    2010-01-01

    Objective:The aim of the study was to review the clinical records of 122 patients with gastrointestinal stromal tumors(GISTs)and analyze their clinicopathologic and immunohistochemical characteristics.Methods:The medic records of 122 patients with GISTs during the periods from January 2002 to May 2010 were reviewed.All tumors were confirmed by histological and immunohistochemical analyses.Results:The tumors occurred in 59 males and 63 females,ranging from 25to 77 years.Of all cases,46 cases originated from stomach,42 from small intestine,17 from colon and rectum and 9 from retroperitoneal cavity and 4 cases from extra-gastrointestinal site.Liver was the most common organ that tumors metastases involved.Immunohistochemically,there were 114 tumors being positive for CD117 while 8 tumors negative for it.The frequencies of CD34 positive were higher in the stomach and rectum(89.1% and 86.7% respectively)than in the small intestine(64.3%,P < 0.05).Higher expression of SMA was in the tumors located in small intestine(54.8%)while the expressions of SMA in the gastric and rectal tumors were relatively low(21.7% and 20.0% respectively,P < 0.05).Conclusion:Gastrointestinal stromal tumors can occur in the gastrointestinal tract as well as in the extra-gastrointestinal sites.The frequencies of CD34 and SMA expression vary significantly with different locations.

  11. Enhanced Web-Based Otitis Study Case vs. Simple Paper-Case: Impact on Medical Student Objective Structured Clinical Exam Performance

    Directory of Open Access Journals (Sweden)

    Michael H. Malloy, M.D., M.S.

    2002-01-01

    Full Text Available Background: Distance education methods have taken on greater importance as medical student education has moved off campus into the community. What the best methods are for conveying information to students at distant sites has not been determined. Objective: To determine if students at distant community sites who received an otitis media study case by e-mail that was enhanced with a referral to a web-based otitis study case, performed better on otitis OSCE stations than students who received the same case not enhanced with visuals or referrals to a web-based otitis case. Design/Methods: Students were randomized by community site to receive either the enhanced (E or simple otitis study case (S. Students were e-mailed an otitis media study case during the 5th week of the rotation. Those randomized to the E-case received a case that started with a case scenario followed by a "Task" that instructed them to go to this web address: http://www.aap.org/otitismedia/www/vc/ear/index.cfm (American Academy of Pediatrics Otitis Web Site. They were then to select "Case 1" which was a continuation of the case scenario present on their e-mail. A list of learning objectives was also printed on the e-mail. Students receiving the S-case viewed the same case scenario and objectives, but were not instructed to go to the web page. All students rotated through two OSCE otitis stations. In the first station they interviewed a simulated patient(OSCE-SP and counseled her on the management of her 12 month old with otitis. Within that station they viewed a video of a pneumoscopic exam of two ears, one ear with otitis and the other ear normal. At the 2nd otitis station the student presented the case to a faculty and was asked a series of questions about otitis media(OSCE-PR. Scores on the two stations were compared by group. Results: There were 198 students who took the OSCE. 178 (90% responded to a survey that indicated they had opened and read the e-mailed case. There

  12. Selection and ranking of occupational safety indicators based on fuzzy AHP: A case study in road construction companies

    Directory of Open Access Journals (Sweden)

    Janackovic, Goran Lj.

    2013-11-01

    Full Text Available This paper presents the factors, performance, and indicators of occupational safety, as well as a method to select and rank occupational safety indicators based on the expert evaluation method and the fuzzy analytic hierarchy process (fuzzy AHP. A case study is done on road construction companies in Serbia. The key safety performance indicators for the road construction industry are identified and ranked according to the results of a survey that included experts who assessed occupational safety risks in these companies. The case study confirmed that organisational factors have a dominant effect on the quality of the occupational health and safety management system in Serbian road construction companies.

  13. The shallows: Development of Alibaba in Chinese domestic logistics system : A Case Study Based Analysis

    OpenAIRE

    Liu, Shun

    2015-01-01

    The aim of the research is to critically analyse the influence of Alibaba as 3PL service providers for Chinese businesses needs and Domestic Logistics. Alibaba is the case study selected for discussion here. Mixed research methods are used, the research is a mix of both primary data and secondary data. A primary data collection method has been used where consumers were queried The aim of the research is to critically analyse the influence of Alibaba as 3PL service providers for Chinese busine...

  14. Open Access and Database Anonymization an Open Source Procedure Based on an Italian Case Study

    OpenAIRE

    Leschiutta, Luca; Futia, Giuseppe

    2014-01-01

    The only method, believed to be compliant to privacy laws, to open a database that contains personal data is anonymization. This work is focused on a car accidents database case study and on the Italian DP law. Database anonymization is described from a procedural point of view and it is explained how it is possible to complete the whole process relying solely on widespread open-source software applications. The proposed approach is empirical and is founded on the letter of the Italian privac...

  15. Towards a Corpus-Based Analysis of Anglicisms in Spanish: A Case Study

    OpenAIRE

    José L. Oncins-Martínez

    2009-01-01

    This paper aims to show some of the advantages of and the need for using corpora for exploring and assessing Anglicisms in contemporary Spanish. In order to do this a case study is presented: the adverb dramáticamente, as it is taking on the new sense ‘espectacularmente’ under the influence of English dramatically. The presence of this adverb with this new sense in contemporary Spanish is explored and supported with the data found in CORDE and CREA, the two corp...

  16. Fifteen Weddings and a Funeral: Case Studies and Resilience-based Management

    Directory of Open Access Journals (Sweden)

    Ann P. Kinzig

    2006-06-01

    Full Text Available “Resilience theory” is a systematic methodology for understanding the dynamics of coupled social-ecological systems (SESs. Its ongoing development requires that resilience theory be confronted with case studies to assess its capacity to help understand and develop policy for SESs. This paper synthesizes the findings from several papers in the special feature "Exploring Resilience in Social-Ecological Systems" that do just this. It then highlights key challenges facing resilience as a theory for understanding SESs and provides some avenues for future research.

  17. Investigation of an online, problem-based introduction to nuclear sciences: A case study

    International Nuclear Information System (INIS)

    An online, grant-funded course on nuclear engineering in society was developed at a large Midwestern university with the goal of providing non-majors a meaningful introduction to the many applications of nuclear science in a modern society and to stimulate learner interest in academic studies and/or professional involvement in nuclear science. Using a within-site case study approach, the current study focused on the efficacy of the online learning environment's support of learners' acquisition of knowledge and the impact of the environment on learners' interest in and beliefs about nuclear sciences in society. Findings suggest the environment successfully promoted learning and had a positive impact on learners' interests and beliefs. (authors)

  18. Pathological study of 130 cases of nonalcoholic fatty liver disease based on NASH-CRN system

    Institute of Scientific and Technical Information of China (English)

    ZHOU Guangde; ZHAO Jingmin; DING Xiaohui; PAN Deng; SUN Yanling; YANG Jianfa; ZHAO Yulai

    2007-01-01

    To summarize the pathological features of nonalcoholic liver disease(NAFLD)in China based on a histological scoring system for NAFLD designed by the Pathology Committee of NASH Clinical Research Network(NASHCRN),the specimens of liver needle biopsies from 130 patients with NAFLD were histopathologically analyzed by haematoxylin eosin,reticular fiber and Masson trichrome stain.Immunohistochemistry staining was used to exclude non-NAFLD cases combined with clinical data.Hepatic steatosis,lobular inflammation,hepatocytic ballooning and fibrosis were presented widespread in NAFLD liver tissues.Furthermore,macrovesicular steatosis predominantly located in acinar zone 3 was the main histologic feature of NAFLD and lobular inflammation was usually presented mildly.Hepatocyte ballooning was observed in 94.6% of all 130 cases.Mild perisinusoidal fibrosis and periportal fibrosis were often observed in stage 1 cases.According to the statistic analysis,hepatic steatosis was positively correlated with lobular inflammation,hepatocytic ballooning and fibrosis (r=0.587,0.488,0.374,respectively,all P value<0.01).The number of microgranulomas,lipogranulomas and apoptotic bodies increased following severity of steatosis,lobular inflammation and fibrosis.Meanwhile,the number of megamitochondria and glycogen nuclei was paralleveled to the degree of hepatocytic ballooning(P value all<0.01).We suggest that the role of portal inflammation should be emphasized besides hepatic steatosis,lobular inflammation,hepatocyte ballooning and fibrosis in diagnosis and evaluation of NAFLD.It needs to be further verified whether microgranulomas,lipogranulomas and apoptosis bodies could be used as histopathological markers of development of NAFLD.The number of megamitochondria is more frequently be found in NAFLD,while in alcoholic liver diseases was Mallory bodies.

  19. Surgical History and the Risk of Endometriosis: A Hospital-Based Case-Control Study.

    Science.gov (United States)

    Liu, Xishi; Long, Qiqi; Guo, Sun-Wei

    2016-09-01

    Women tend to receive more surgical procedures than men. Our mouse study shows that surgical stress promotes the development of endometriosis. This study was undertaken to test the hypothesis that surgery increases the risk of endometriosis. We recruited 208 patients with ovarian endometrioma and 212 age-matched patients with ovarian teratoma and retrieved information on the history of any surgical procedures after menarche, grouped by laparotomy, laparoscopy, gynecologically related procedures, cesarean section, and surgeries performed on torso and extremities was recorded. We then evaluated the association, if any, between endometriosis and history of surgical procedures. Cases and controls were comparable with respect to age, marital status, education level, and occupation. Eleven (5.3%) cases had laparotomy before the index surgery while 4 (1.9%) controls did. Sixty-six (31.7%) cases had Cesarean section while 53 (25.0%) controls did. Multivariate analysis identified age, at the index surgery laparotomy, and cesarean section as 3 factors positively associated with the risk of endometriosis while parity was found to be negatively associated with the risk. Laparotomy was associated with increased risk of endometriosis (odds ratio [OR] = 3.64, 95% confidence interval [CI] = 1.08-12.31), while cesarean section was associated with 2-fold increase in risk (OR = 2.16, 95% CI = 1.31-3.55). Both laparotomy and cesarean section may increase the risk of endometriosis probably by activation of adrenergic signaling, thus facilitating angiogenesis and accelerating the growth of endometriotic lesions that are already in existence. This finding may have important ramifications for the perioperative management of patients with increased risk or recurrence risk of endometriosis. PMID:26919976

  20. Case Studies of Secondary School Teachers Designing Socioscientific Issues-Based Instruction and Their Students' Socioscientific Reasoning

    Science.gov (United States)

    Karahan, Engin

    Addressing socioscientific issues (SSI) has been one of the main focuses in science education since the Science, Technology, and Society (STS) movement in the 1970s (Levinson, 2006); however, teaching controversial socioscientific issues has always been challenging for teachers (Dillon, 1994; Osborne, Duschl, & Fairbrother, 2002). Although teachers exhibit positive attitudes for using controversial socioscientific issues in their science classrooms, only a small percentage of them actually incorporate SSI content into their science curricula on a regular basis (Sadler, Amirshokoohi, Kazempour, & Allspaw, 2006; Lee & Witz, 2009). The literature in science education has highlighted the signi?cant relationships among teacher beliefs, teaching practices, and student learning (Bryan & Atwater, 2002; King, Shumow, & Lietz, 2001; Lederman, 1992). Despite the fact that the case studies present a relatively detailed picture of teachers' values and motivations for teaching SSI (e.g. Lee, 2006; Lee & Witz, 2009; Reis & Galvao, 2004), these studies still miss the practices of these teachers and potential outcomes for their students. Therefore, there is a great need for in-depth case studies that would focus on teachers' practices of designing and teaching SSI-based learning environments, their deeper beliefs and motivations for teaching SSI, and their students' response to these practices (Lee, 2006). This dissertation is structured as three separate, but related, studies about secondary school teachers' experiences of designing and teaching SSI-based classes and their students' understanding of science and SSI reasoning. The case studies in this dissertation seek answers for (1) teachers' practices of designing and teaching SSI-based instruction, as well as its relation to their deeper personal beliefs and motivations to teach SSI, and (2) how their students respond to their approaches of teaching SSI in terms of their science understanding and SSI reasoning. The first paper

  1. Risk factors for homicide victimization in post-genocide Rwanda: a population -based case- control study

    OpenAIRE

    Rubanzana, Wilson; Ntaganira, Joseph; Freeman, Michael D.; Hedt-Gauthier, Bethany L

    2015-01-01

    Background: Homicide is one of the leading causes of mortality in the World. Homicide risk factors vary significantly between countries and regions. In Rwanda, data on homicide victimization is unreliable because no standardized surveillance system exists. This study was undertaken to identify the risk factors for homicide victimization in Rwanda with particular attention on the latent effects of the 1994 genocide. Methods: A population-based matched case–control study was conducted, with sub...

  2. Case Studies on Sustainable Buildings

    OpenAIRE

    Hui, Sam CM

    2005-01-01

    This web site is developed with the aim to promote sustainable design and planning of buildings. A knowledge base of case studies and resources has been established to illustrate the sustainable design strategies and features in realistic building projects all over the world. The database of case studies can be searched by project names, locations, design strategies and design features.

  3. Core-firm Based View on the Mechanism of Constructing a Corporate Innovation Ecosystem: A Case Study of Haier Group

    DEFF Research Database (Denmark)

    Jiang, Shimei; Wang, Ziyuan; Hu, Yimei

    2016-01-01

    The fierce transformation of the competitive status of business world in the 21st century has urged the innovation activities turned from mechanistic and deterministic to ecological and organic. The study firstly defines the concept of core firm based on reviewing existing corporate innovation...... ecosystem literature, and then adopts a multi-embedded case study method on Haier Group’s corporate innovation ecosystem, focusing on six exploratory sub-cases. Based on qualitative coding and analysis on the value realization of six new product/technology of the Haier Group, we investigate how a core firm...... constructing a corporate innovation ecosystem through building up an innovation platform that include multi-level collaborative relationships based on different technologies; while at the same time integrating non-technological issues such as strategy, culture, management, organization, institution and market...

  4. From needs to competencies : a case study on the integration of a rights based approach into NGO practises

    OpenAIRE

    Mesiäislehto, Virpi

    2010-01-01

    The objective of this qualitative case study is to provide knowledge on the possibilities of incorporating a rights based approach (RBA) into practises of non-governmental organisations (NGOs) in the context of development and children. The study is confined to examine the possibilities of RBA in realising children’s rights within the child sponsorship programme (CSP) of a Finnish NGO, Fida International (Fida), and the conceptualisation of the child in regard to different appr...

  5. Temperament and School-Based Mental Health Practice: A Case Study of Interdisciplinary Collaboration

    Science.gov (United States)

    Carpenter-Aeby, Tracy; Aeby, Victor G.; Boyd, Jane S.

    2007-01-01

    This study describes the application of temperament styles to school-based mental health practice in an alternative school and illustrates how a multidisciplinary team consisting of a special education teacher, health educator, and social worker used temperament to maximize effective interactions with a student who had been placed in the school…

  6. Managing School-Based Curriculum Innovations: A Hong Kong Case Study

    Science.gov (United States)

    Law, Edmond H. F.; Wan, Sally W. Y.; Galton, Maurice; Lee, John C. K.

    2010-01-01

    This study was originally designed to explore the impact of a distributed approach to developing curriculum leadership among schoolteachers. Previous papers have focused on reporting evidence of teacher learning in the process of engaging teachers in various types of curriculum decision-making in an innovation project based on interview data. This…

  7. Assessing Long-Term Effects of Inquiry-Based Learning: A Case Study from College Mathematics

    Science.gov (United States)

    Kogan, Marina; Laursen, Sandra L.

    2014-01-01

    As student-centered approaches to teaching and learning are more widely applied, researchers must assess the outcomes of these interventions across a range of courses and institutions. As an example of such assessment, this study examined the impact of inquiry-based learning (IBL) in college mathematics on undergraduates' subsequent grades…

  8. Computer-Based Basic Skills Instruction in a CETA Funded Project: A Case Study.

    Science.gov (United States)

    Caldwell, Robert M.; Hedl, John J., Jr.

    1984-01-01

    Reports on a study that (1) examined the effectiveness of computer-based education in developing literacy and mathematics skills in young adults to enable them to secure unsubsidized employment and (2) compared motivation of CETA-funded students with those who sought training voluntarily. Discusses failures of CETA training projects and makes…

  9. A Case Study in Project-Based Learning: An International Partnership

    Science.gov (United States)

    Smith, Rachel Korfhage

    2010-01-01

    As our world becomes more integrated, international business students should develop skills that match corporations' needs. Moreover, students need hands-on, problem-solving, team-based, critical-thinking skills that companies demand. Students need international business experience but many of them lack the funds or support to study or intern…

  10. Case Study: Use of Problem-Based Learning to Develop Students' Technical and Professional Skills

    Science.gov (United States)

    Warnock, James N.; Mohammadi-Aragh, M. Jean

    2016-01-01

    Problem-based learning (PBL) is a pedagogy that has attracted attention for many biomedical engineering curricula. The aim of the current study was to address the research question, "Does PBL enable students to develop desirable professional engineering skills?" The desirable skills identified were communication, teamwork, problem…

  11. Instruction in Divergent Thinking for Conceptual Design: A Case Study Based on a Corkscrew

    Directory of Open Access Journals (Sweden)

    Ying-Chieh Liu

    2015-09-01

    Full Text Available Abstraction is a powerful tool for designers in the conceptual design stage. Such abstractions take various forms, and little is known as to how a particular method of abstraction would support designers in specific design cases. A method is proposed which includes a deliberate step for divergent thinking. The method presents learners with an abstract representation of an existing artifact, and encourages them to explore potential concepts that are different in style but are based on the same or similar abstraction as that given in the representation. To evaluate how the method would help novice designers, a summer workshop activity of designing stylish corkscrews was conducted with twelve recent graduates from industrial design graduate programs. The students come from a variety of academic backgrounds. The processes for concept generation, making a prototype and a summarized statement are the main inputs used for activity assessment. Students proposed a total of 56 design concepts, with an average of 4.7 concepts per student. Design-related students (six participants generated between 3 and 12 concepts, while students without a design background generated between 1 to 6 concepts. The concepts were divided into five classes based on appearance: human-like, animal-like, artificial product-like, plant-like, and phenomena-like. Of the 12 students, three produced mechanically functional prototypes. Based on student feedback, the pros of the instructional approach included support for the linking of concepts, encouraged learner engagement, and promoted specific thinking processes. Results suggested this method has potential for supporting positive learning outcomes, particularly in generating a range of stylish concepts based on an existing artifact within a limited time frame. However, prototype development would require additional support.

  12. From functional programming to multicore parallelism: A case study based on Presburger Arithmetic

    DEFF Research Database (Denmark)

    Dung, Phan Anh; Hansen, Michael Reichhardt

    2011-01-01

    in the SMT-solver Z3 [8] which has the capability of solving Presburger formulas. Functional programming is well-suited for the domain of decision procedures, and its immutability feature helps to reduce parallelization effort. While Haskell has progressed with a lot of parallelismrelated research [6], we......The overall goal of this work is studying parallelization of functional programs with the specific case study of decision procedures for Presburger Arithmetic (PA). PA is a first order theory of integers accepting addition as its only operation. Whereas it has wide applications in different areas...... bound [7]. We investigate these decision procedures in the context of multicore parallelism with the hope of exploiting multicore powers. Unfortunately, we are not aware of any prior parallelism research related to decision procedures for PA. The closest work is the preliminary results on parallelism...

  13. Analysis of place distribution of urban services, based on people demanding (case study: Estahban city

    Directory of Open Access Journals (Sweden)

    Kh. Bazi

    2013-01-01

    Full Text Available Extended abstract1- IntroductionIn recent decades as the population in cities of country, which had been influenced by natural population growth of cities and migration of people in towns and rural to middle cities and metro polices, increases city spaces and infrastructures, which are needed have not been equipped.Urban services are the means for managing urban development and a prominent cause in continuing city life, which without it the life of citizens has been stopped. Its optimal and systematic distribution consistent with the people’s demands in the process of urban planning is very important.Urban services have been considered as one of clear indicators of civilization from many years ago.Today as the civilization increases, urban services and their qualities have been regarded by experts, planners and citizens, so urban services have been followed by urbanization development.2- Methodology In this study through library studies, referring to the relevant agencies, field observation and analysis and evaluation the questionnaire given to residents of various neighborhoods in Estahban city with SPSS were presented.To evaluate the proportion of urban services and people demand six neighborhoods were chosen among 15 neighborhoods of Estahban. (Two neighborhoods of each region. These neighborhoods were chosen based on place- cluster sampling and also economic-social conditions of them and detailed plan of Estahban. In this research a wealthy neighborhood and poor neighborhood were chosen in each region. By using general Cochran formula we obtained 300 sample size . So 300 questionnaires had been distributed among the residents.3- DiscussionAfter 1350, Estahban city faces numerous problems in supplying urban services, because of population growth, physical development in addition to injustice distribution of urban services. These problems have also been strengthened by people who live in more deprived parts of the township to use the urban

  14. Change Detection Based on Persistent Scatterer Interferometry - Case Study of Monitoring AN Urban Area

    Science.gov (United States)

    Yang, C. H.; Soergel, U.

    2015-08-01

    Persistent Scatterer Interferometry (PSI) is a technique to extract subtle surface deformation from sets of scatterers identified in time-series of SAR images which feature temporally stable and strong radar signal (i.e., Persistent Scatterers, PS). Because of the preferred rectangular and regular structure of man-made objects, PSI works particularly well for monitoring of settlements. Usually, in PSI it is assumed that except for surface motion the scene is steady. In case this is not given, corresponding PS candidates are discarded during PSI processing. On the other hand, pixel-based change detection relying on local comparison of multi-temporal images typically highlights scene modifications of larger size rather than detail level. In this paper, we propose a method to combine these two types of change detection approaches. First, we introduce a local change-index based on PSI, which basically looks for PS candidates that remain stable over a certain period of time, but then break down suddenly. In addition, for the remaining PS candidates we apply common PSI processing which yields attributes like velocity in line-of-sight. In order to consider context, we apply now spatial filtering according to the derived attributes and morphology to exclude outliers and extract connect components of similar regions at the same time. We demonstrate our approach for test site Berlin, Germany, where, firstly, deformation-velocities on man-made structures are estimated and, secondly, some construction-sites are correctly recognized.

  15. Replacement of traditional lectures with computer-based tutorials: a case study

    Directory of Open Access Journals (Sweden)

    Derek Lavelle

    1996-12-01

    Full Text Available This paper reports on a pilot project with a group of 60 second-year undergraduates studying the use of standard forms of contract in the construction industry. The project entailed the replacement of two of a series of nine scheduled lectures with a computer-based tutorial. The two main aims of the project were to test the viability of converting existing lecture material into computer-based material on an in-house production basis, and to obtain feedback from the student cohort on their behavioural response to the change in media. The effect on student performance was not measured at this stage of development.

  16. Ambient Vibration Based Damage Diagnosis Using Statistical Modal Filtering and Genetic Algorithm: A Bridge Case Study

    Directory of Open Access Journals (Sweden)

    S. El-Ouafi Bahlous

    2013-01-01

    Full Text Available The authors recently developed a damage identification method which combines ambient vibration measurements and a Statistical Modal Filtering approach to predict the location and degree of damage. The method was then validated experimentally via ambient vibration tests conducted on full-scale reinforced concrete laboratory specimens. The main purpose of this paper is to demonstrate the feasibility of the identification method for a real bridge. An important challenge in this case is to overcome the absence of vibration measurements for the structure in its undamaged state which corresponds ideally to the reference state of the structure. The damage identification method is, therefore, modified to adapt it to the present situation where the intact state was not subjected to measurements. An additional refinement of the method consists of using a genetic algorithm to improve the computational efficiency of the damage localization method. This is particularly suited for a real case study where the number of damage parameters becomes significant. The damage diagnosis predictions suggest that the diagnosed bridge is damaged in four elements among a total of 168 elements with degrees of damage varying from 6% to 18%.

  17. Breast cancer risk associated with different HRT formulations: a register-based case-control study

    Directory of Open Access Journals (Sweden)

    Thai Do

    2006-09-01

    Full Text Available Abstract Background Previous epidemiological studies have inconsistently shown a modestly increased breast cancer risk associated with hormone replacement therapy (HRT. Limited information is available about different formulations – particularly concerning different progestins. Methods A case-control study was performed within Germany in collaboration with regional cancer registries and tumor centers. Up to 5 controls were matched breast cancer cases. Conditional logistic regression analysis was applied to estimate crude and adjusted odds ratios (OR and 95% confidence intervals (95% CI. Stratified analyses were performed to compare the risk of different estrogens, progestins, and combinations. Results A total of 3593 cases of breast cancer were identified and compared with 9098 controls. The adjusted overall risk estimate for breast cancer (BC associated with current or past use of HRT was 1.2 (1.1–1.3, and almost identical for lag times from 6 months to 6 years prior to diagnosis. No significant trend of increasing BC risk was found with increasing duration of HRT use, or time since first or last use in aggregate. Many established BC risk factors significantly modified the effect of HRT on BC risk, particularly first-degree family history of BC, higher age, lower education, higher body mass index (BMI, and never having used oral contraceptives (OCs during lifetime. Whereas the overall risk estimates were stable, the numbers in many of the sub-analyses of HRT formulation groups (estrogens, progestins, and combinations were too small for strong conclusions. Nevertheless, the BC risk seems not to vary much across HRT formulation subgroups. In particular, no substantial difference in BC risk was observed between HRT containing conjugated equine estrogens (CEE or medroxyprogesterone acetate (MPA and other formulations more common in Europe. Conclusion The BC risk of HRT use is rather small. Low risk estimates for BC and a high potential for

  18. The role of animated pedagogical agents in scenario-based language e-learning: a case-study

    OpenAIRE

    Reategui, Eliseo; Polonia, Eunice; Roland, Letícia

    2007-01-01

    Scenario-based language e-learning (SBeL) is focused on contextual learning, since it uses authentic activities that can improve communication skills. This paper reports a case-study that proposes the use of animated pedagogical agents (APAs) in a Brazilian Portuguese web-based course built under a mix of task- and scenario-based approaches. Its main purpose is to discuss how APAs can be used to improve students' communicative skills, cultural awareness and level of interaction with course's ...

  19. Factors influencing a problem-based learning implementation: A case study of IT courses

    Science.gov (United States)

    Darus, Norida Muhd; Mohd, Haslina; Baharom, Fauziah; Saip, Mohamed Ali; Puteh, Nurnasran; Marzuki @ Matt, Zaharin; Husain, Mohd Zabidin; Yasin, Azman

    2016-08-01

    IT students must be trained to work efficiently as teamwork. One of the techniques that can be used to train them is through Problem-Based Learning (PBL) approach. The PBL implementation can be influenced by various factors depending on the ultimate goal of the study. This study is focusing on the IT students' perception of the PBL implementation. The student's perception is important to ensure the successfulness of the PBL implementation. Therefore, it is important to identify the factors that might influence the implementation of PBL of IT courses. This study aims to identify some catalyst factors that may influence the PBL implementation of IT courses. The study involved three (3) main phases: identifying PBL implementation factors, constructing a PBL model, and PBL model validation using statistical analysis. Four main factors are identified: PBL Characteristics, PBL Course Assessment, PBL Practices, and PBL Perception. Based on these four factors, a PBL model is constructed. Then, based on the proposed PBL model, four hypotheses are formulated and analyzed to validate the model. All hypotheses are significantly acceptable. The result shows that the PBL Characteristics and PBL Course Assessment factors are significantly influenced the PBL Practices and indirectly influenced the Students' Perception of the PBL Implementation for IT courses. This PBL model can assist decision makers in enhancing the PBL teaching and learning strategy for IT courses. It is also can be tested to other courses in the future.

  20. Juxtaposition of system dynamics and agent-based simulation for a case study in immunosenescence.

    Directory of Open Access Journals (Sweden)

    Grazziela P Figueredo

    Full Text Available Advances in healthcare and in the quality of life significantly increase human life expectancy. With the aging of populations, new un-faced challenges are brought to science. The human body is naturally selected to be well-functioning until the age of reproduction to keep the species alive. However, as the lifespan extends, unseen problems due to the body deterioration emerge. There are several age-related diseases with no appropriate treatment; therefore, the complex aging phenomena needs further understanding. It is known that immunosenescence is highly correlated to the negative effects of aging. In this work we advocate the use of simulation as a tool to assist the understanding of immune aging phenomena. In particular, we are comparing system dynamics modelling and simulation (SDMS and agent-based modelling and simulation (ABMS for the case of age-related depletion of naive T cells in the organism. We address the following research questions: Which simulation approach is more suitable for this problem? Can these approaches be employed interchangeably? Is there any benefit of using one approach compared to the other? Results show that both simulation outcomes closely fit the observed data and existing mathematical model; and the likely contribution of each of the naive T cell repertoire maintenance method can therefore be estimated. The differences observed in the outcomes of both approaches are due to the probabilistic character of ABMS contrasted to SDMS. However, they do not interfere in the overall expected dynamics of the populations. In this case, therefore, they can be employed interchangeably, with SDMS being simpler to implement and taking less computational resources.

  1. Socio-economic status and lifestyle factors are associated with achalasia risk: a population-based case-control study.

    OpenAIRE

    Coleman, Helen G; Gray, Ronan T.; Lau, Kar W.; McCaughey, Conall; Coyle, Peter V.; Murray, Liam J; Johnston, Brian T

    2016-01-01

    AIM: To evaluate the association between various lifestyle factors and achalasia risk.METHODS: A population-based case-control study was conducted in Northern Ireland, including n= 151 achalasia cases and n = 117 age- and sex-matched controls. Lifestyle factors were assessed via a face-to-face structured interview. The association between achalasia and lifestyle factors was assessed by unconditional logistic regression, to produce odds ratios (OR) and 95% confidence interval (CI).RESULTS: Ind...

  2. A population-based case-control study of the safety of oral anti-tuberculosis drug treatment during pregnancy

    DEFF Research Database (Denmark)

    Czeizel, A.E.; Rockenbauer, M.; Olsen, J.;

    2001-01-01

    OBJECTIVE: To study the human teratogenic potential of isoniazid and other anti-tuberculosis drug treatment during pregnancy. DESIGN AND SETTING: Cases from a large population-based dataset at the Hungarian Case-Control Surveillance of Congenital Abnormalities, and controls from the National Birth...... OUTCOME MEASURES: Congenital abnormalities in newborn infants and fetuses diagnosed prenatally during the second and third trimesters, and postnatally from birth to the age of one year. RESULTS: Of 38,151 controls, 29 (0.08%) were exposed to anti-tuberculosis drug treatment during pregnancy; the...... Registry, between 1980 and 1996. Information on all oral anti-tuberculosis drug treatments during pregnancy was medically recorded. STUDY PARTICIPANTS: Women who had newborns or fetuses with congenital abnormalities (case group), and women who had babies with no congenital abnormality (control group). MAIN...

  3. Delimitating central areas of cities based on road density: a case study of Guangzhou City

    Science.gov (United States)

    Zhang, Qingnian; Lu, Xueqiu

    2009-10-01

    The central area of a city is an important functional unit in many urban studies. It is a region where business concentrates and municipal facilities densely distribute. Traditionally, statistics of economic and social phenomena can be used to delimitate their boundaries. However, traditional methods based on economic and social investigation are labor-intensive and sometimes inaccurate. Alternatively, road networks acting as a kind of infrastructure reflect the association of locations. Thus the concentration of road networks indicates the congestion of social-economic activities and municipal facilities to some extent. Based on density analysis of road networks, the area where roads densely distribute is recognized as the central area of a city. Taking Guangzhou City as an example, the road network was studied on a set of spatial scopes, and the central area was delimitated and analyzed. Results showed that the road-density-based delimitation had to be adjusted according to the road system, and the delimitated area was consistent to the real central area to some extent. Since road data is much accessible, road-based method is useful and practical when short of socialeconomic data.

  4. Object-based cropland degradation identification: a case study in Uzbekistan

    Science.gov (United States)

    Dubovyk, Olena; Menz, Gunter; Conrad, Christopher; Khamzina, Asia

    2012-10-01

    Sustainability of irrigated agriculture-based economies, such as in Central Asia, is threatened by cropland degradation. The field-based identification of the degraded agricultural areas can aid in developing appropriate land rehabilitation and monitoring programs. This paper combined the object-based change detection and spectral mixture analysis to develop an approach for identifying parcels of irrigated degraded cropland in Northern Uzbekistan, Central Asia. A linear spectral unmixing, followed by the object-based change vector analysis, was applied to the multiple Landsat TM images, acquired in 1987 and 2009. Considering a spectral dimensionality of Landsat TM, a multiple 4-endmember model (green vegetation, water, dark soil, and bright soil) was set up for the analysis. The spectral unmixing results were valid, as indicated by the overall root mean square errors of <2.5% reflectance for all images. The results of change detection revealed that about 33% (84,540 ha) of cropland in the study area were affected by the degradation processes to varying degrees. Spatial distribution of degraded fields was mainly associated with the abandoned fields and lands with inherently low fertile soils. The proposed approach could be elaborated for a field-based monitoring of cropland degradation in similar landscapes of Central Asia and elsewhere.

  5. Fuel efficiency and CO2 emissions of biomass based haulage in Ireland - A case study

    OpenAIRE

    Devlin, Ger; Klvac, Radomir; McDonnell, Kevin

    2013-01-01

    The purpose of this study was to analyse how biomass based haulage in Ireland performed as a measure of efficiency under 4 main criteria; distance travelled, fuel consumption, fuel consumption per unit of biomass hauled and diesel CO2 emissions. The applicability of truck engine diagnostic equipment was tested to analyse the schedule of engine data that could be recorded in real-time from a 5 axle articulated biomass truck. This identified how new on board truck technology in Ireland could be...

  6. Mindfulness-Based Cognitive Therapy for Trichotillomania: A Bayesian Case-Control Study

    OpenAIRE

    Alexandre Heeren; Charlotte Busana; Charlotte Coussement; Pierre Philippot

    2015-01-01

    Over the last years, mindfulness-based interventions combined with habit reversal training have been demonstrated to be particularly suitable for addressing trichotillomania. However, because these studies always combined mindfulness training to habit reversal without including either a mindfulness or habit reversal condition alone, it is still unclear whether clinical benefits are the consequences of mindfulness or merely result from habit reversal training. The primary purpos...

  7. Optimization of a forest harvesting set based on the Queueing Theory: Case study from Karelia

    OpenAIRE

    Shegelman Ilya; Budnik Pavel; Morozov Evsey

    2015-01-01

    The modern technological process of timber harvesting is a complex system both technically and organizationally. Nowadays, the study of such systems and improvement of their efficiency is impossible without the use of mathematical modeling methods. The paper presents the methodology for the optimization of logging operations based on the queueing theory. We show the adapted queueing model, which characterizes the process of logging with the use of a harvesting set consisting of harvesters and...

  8. Teachers' Views on Inquiry-Based Learning in Science - A Case Study from an International School

    OpenAIRE

    Panjwani, Neelam

    2015-01-01

    This thesis presents a study of teachers' perspectives on inquiry-oriented approaches and how they conceptualize them. Five teachers from an international school were interviewed. They were asked to describe how they interpret inquiry-based teaching, and to give examples of their own teaching practices in line with inquiry-oriented teaching. Additionally, the teachers were asked for the constraints they face in implementing an inquiry lesson. The results from the inductive analysis show that ...

  9. Exploring Collaborative and Community Based Planning in Tourism Case Study Sitia-Cavo Sidero Project

    OpenAIRE

    Katsouli, Penelope

    2007-01-01

    The present paper has explored the policy planning and development in emerging tourism settings in Sitia. Comprehensively, this study, in the name of sustainable development, focused on the extent of collaborative and community-based planning. For that reason exploratory research has been used; the context and the structure of this paper aimed to uncover the socially constructed reality of Sitia's stakeholders, within the dynamic environment, and respond to and questions. Therein significant ...

  10. Zombie Division : a methodological case study for the evaluation of game-based learning

    OpenAIRE

    Habgood, M. P. Jacob

    2015-01-01

    This paper discusses the methodological designs and technologies used to evaluate an educational videogame in order to support researchers in the design of their own evaluative research in the field of game-based learning. The Zombie Division videogame has been used to empirically evaluate the effectiveness of a more intrinsically integrated approach to creating educational games. It was specifically designed to deliver interventions as part of research studies examining differences in learni...

  11. Gene Transfection in High Serum Levels: Case Studies with New Cholesterol Based Cationic Gemini Lipids

    OpenAIRE

    Misra, Santosh K; Biswas, Joydeep; Kondaiah, Paturu; Bhattacharya, Santanu

    2013-01-01

    Background: Six new cationic gemini lipids based on cholesterol possessing different positional combinations of hydroxyethyl (-CH2CH2OH) and oligo-oxyethylene -(CH2CH2O)(n)- moieties were synthesized. For comparison the corresponding monomeric lipid was also prepared. Each new cationic lipid was found to form stable, clear suspensions in aqueous media. Methodology/Principal Findings: To understand the nature of the individual lipid aggregates, we have studied the aggregation properties using ...

  12. Customer Orientation of Service Employees: A Case Study of Iranian Islamic Banking (Based on COSE Model)

    OpenAIRE

    Kambiz Heidarzadeh Hanzaee,; Majid Mirvaisi

    2011-01-01

    With the performance of service personnel often constituting a major element of a service per se, the customer orientation of service employees (COSE) is often regarded as a main determinant of service firm's success. The purpose of this study is Understands how customer orientation (CO) of service employees (SE) affects customer satisfaction (CS), customer commitment (CC), customer retention (CR) and increasing service quality (SQ) in Iranian Islamic banking sector. This is based on 300 resp...

  13. Mindfulness-Based Cognitive Therapy for Trichotillomania: A Bayesian Case-Control Study

    OpenAIRE

    Heeren, Alexandre; Busana, Charlotte; Coussement, Charlotte; Philippot, Pierre

    2015-01-01

    Over the last years, mindfulness-based interventions combined with habit reversal training have been demonstrated to be particularly suitable for addressing trichotillomania. However, because these studies always combined mindfulness training to habit reversal without including either a mindfulness or habit reversal condition alone, it is still unclear whether clinical benefits are the consequences of mindfulness or merely result from habit reversal training. The primary purpose of the presen...

  14. Factors associated with syphilis infection: a comprehensive analysis based on a case-control study.

    Science.gov (United States)

    Xiao, Y; Li, S-L; Lin, H-L; Lin, Z-F; Zhu, X-Z; Fan, J-Y; Gao, K; Zhang, H-L; Lin, L-R; Liu, L-L; Tong, M-L; Niu, J-J; Yang, T-C

    2016-04-01

    This study aimed to comprehensively evaluate factors that influence the likelihood of syphilis infection from risk-taking behaviours and medical conditions. A retrospective case-control study was conducted by enrolling 664 syphilis inpatients (excluding 11 congenital syphilis patients) and 800 sex- and age-matched controls. Medical histories, clinical data and patient interview data were collected and subjected to logistic regression analyses. The prevalence of syphilis in the study population was 3·9% (675/17 304). By univariate analysis, syphilis infection was associated with migration between cities, marital status, smoking, reproductive history, hypertension, elevated blood urea nitrogen (BUN) and infection with hepatitis B virus (HBV) (P syphilis-HBV co-infection was observed in HIV-negative patients and further research revealed an association between syphilis and specific HBV serological reactivity. Syphilis was also associated with the frequency, duration and status of tobacco use. Multivariate analysis indicated that syphilis infection was independently associated with migration between cities [adjusted odds ratio (aOR) 1·368, 95% confidence interval (CI) 1·048-1·785], current smoking (aOR 1·607, 95% CI 1·177-2·195), elevated BUN (aOR 1·782, 95% CI 1·188-2·673) and some serological patterns of HBV infection. To prevent the spread of infectious diseases, inpatients and blood donors should be tested for HIV, syphilis, HBV and HCV simultaneously. PMID:26467944

  15. Bias adjustment of satellite-based precipitation estimation using gauge observations: A case study in Chile

    Science.gov (United States)

    Yang, Zhongwen; Hsu, Kuolin; Sorooshian, Soroosh; Xu, Xinyi; Braithwaite, Dan; Verbist, Koen M. J.

    2016-04-01

    Satellite-based precipitation estimates (SPEs) are promising alternative precipitation data for climatic and hydrological applications, especially for regions where ground-based observations are limited. However, existing satellite-based rainfall estimations are subject to systematic biases. This study aims to adjust the biases in the Precipitation Estimation from Remotely Sensed Information using Artificial Neural Networks-Cloud Classification System (PERSIANN-CCS) rainfall data over Chile, using gauge observations as reference. A novel bias adjustment framework, termed QM-GW, is proposed based on the nonparametric quantile mapping approach and a Gaussian weighting interpolation scheme. The PERSIANN-CCS precipitation estimates (daily, 0.04°×0.04°) over Chile are adjusted for the period of 2009-2014. The historical data (satellite and gauge) for 2009-2013 are used to calibrate the methodology; nonparametric cumulative distribution functions of satellite and gauge observations are estimated at every 1°×1° box region. One year (2014) of gauge data was used for validation. The results show that the biases of the PERSIANN-CCS precipitation data are effectively reduced. The spatial patterns of adjusted satellite rainfall show high consistency to the gauge observations, with reduced root-mean-square errors and mean biases. The systematic biases of the PERSIANN-CCS precipitation time series, at both monthly and daily scales, are removed. The extended validation also verifies that the proposed approach can be applied to adjust SPEs into the future, without further need for ground-based measurements. This study serves as a valuable reference for the bias adjustment of existing SPEs using gauge observations worldwide.

  16. Semantic Mining based on graph theory and ontologies. Case Study: Cell Signaling Pathways

    Directory of Open Access Journals (Sweden)

    Carlos R. Rangel

    2016-08-01

    Full Text Available In this paper we use concepts from graph theory and cellular biology represented as ontologies, to carry out semantic mining tasks on signaling pathway networks. Specifically, the paper describes the semantic enrichment of signaling pathway networks. A cell signaling network describes the basic cellular activities and their interactions. The main contribution of this paper is in the signaling pathway research area, it proposes a new technique to analyze and understand how changes in these networks may affect the transmission and flow of information, which produce diseases such as cancer and diabetes. Our approach is based on three concepts from graph theory (modularity, clustering and centrality frequently used on social networks analysis. Our approach consists into two phases: the first uses the graph theory concepts to determine the cellular groups in the network, which we will call them communities; the second uses ontologies for the semantic enrichment of the cellular communities. The measures used from the graph theory allow us to determine the set of cells that are close (for example, in a disease, and the main cells in each community. We analyze our approach in two cases: TGF-ß and the Alzheimer Disease.

  17. The Emerging Microbe Project: Developing Clinical Care Plans Based on Pathogen Identification and Clinical Case Studies

    Directory of Open Access Journals (Sweden)

    Lauren A. O'Donnell

    2015-08-01

    Full Text Available For many students in the health sciences, including doctor of pharmacy (PharmD students, basic and clinical sciences often appear detached from each other. In the infectious disease field, PharmD students additionally struggle with mastering the diversity of microorganisms and the corresponding therapies. The objective of this study was to design an interdisciplinary project that integrates fundamental microbiology with clinical research and decision-making skills. The Emerging Microbe Project guided students through the identification of a microorganism via genetic sequence analysis. The unknown microbe provided the basis for a patient case that asked the student to design a therapeutic treatment strategy for an infected patient. Outside of lecture, students had two weeks to identify the pathogen using nucleotide sequences, compose a microbiology report on the pathogen, and recommend an appropriate therapeutic treatment plan for the corresponding clinical case. We hypothesized that the students would develop a better understanding of the interplay between basic microbiology and infectious disease clinical practice, and that they would gain confidence and skill in independently selecting appropriate antimicrobial therapies for a new disease state. The exercise was conducted with PharmD students in their second professional year of pharmacy school in a required infectious disease course. Here, we demonstrate that the Emerging Microbe Project significantly improved student learning through two assessment strategies (assignment grades and exam questions, and increased student confidence in clinical infectious disease practice. This exercise could be modified for other health sciences students or undergraduates depending upon the level of clinical focus required of the course.

  18. The Emerging Microbe Project: Developing Clinical Care Plans Based on Pathogen Identification and Clinical Case Studies.

    Science.gov (United States)

    O'Donnell, Lauren A; Perry, Michael W; Doup, Dane't R

    2015-12-01

    For many students in the health sciences, including doctor of pharmacy (PharmD) students, basic and clinical sciences often appear detached from each other. In the infectious disease field, PharmD students additionally struggle with mastering the diversity of microorganisms and the corresponding therapies. The objective of this study was to design an interdisciplinary project that integrates fundamental microbiology with clinical research and decision-making skills. The Emerging Microbe Project guided students through the identification of a microorganism via genetic sequence analysis. The unknown microbe provided the basis for a patient case that asked the student to design a therapeutic treatment strategy for an infected patient. Outside of lecture, students had two weeks to identify the pathogen using nucleotide sequences, compose a microbiology report on the pathogen, and recommend an appropriate therapeutic treatment plan for the corresponding clinical case. We hypothesized that the students would develop a better understanding of the interplay between basic microbiology and infectious disease clinical practice, and that they would gain confidence and skill in independently selecting appropriate antimicrobial therapies for a new disease state. The exercise was conducted with PharmD students in their second professional year of pharmacy school in a required infectious disease course. Here, we demonstrate that the Emerging Microbe Project significantly improved student learning through two assessment strategies (assignment grades and exam questions), and increased student confidence in clinical infectious disease practice. This exercise could be modified for other health sciences students or undergraduates depending upon the level of clinical focus required of the course. PMID:26753029

  19. SOFTWARE BASED APPROACH FOR CLASSROOM TEACHING OF ELECTRICAL ENGINEERING COURSES: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Hemant Mehar

    2015-06-01

    Full Text Available Electrical engineering concepts are abstract in nature and difficult to explain using conventional teaching tools. The use of software in teaching holds the potential in providing better learning support as these tools can provide visual representations of complex circuits operation and waveforms for enhanced concept and procedural learning in power electronics. The software packages available for simulation of power electronic circuits include MATLAB, PSPICE and PSIM. In this study the author takes an example of an AC voltage controller to explain the software based teaching approach. The author used two software based simulation tools to explain the AC voltage controller concept and compare the software based approach with the blackboard and power point presentation based technique. Results of different approaches are compared in the last session of this paper, so it is helpful for the faculty of electrical engineering to find the various applications of MATLAB, SIMULINK and PSIM in teaching. Overall students find the simulation approach is helpful for their learning.

  20. SA-based concrete seismic stress monitoring: a case study for normal strength concrete

    Science.gov (United States)

    Hou, S.; Zhang, H. B.; Ou, J. P.

    2016-09-01

    The stress history of concrete structures that have survived an earthquake can serve as a critical index to evaluate the health of the structure. There are currently few reliable monitoring methods to assess concrete stress after a seismic event. Piezoelectric-based smart aggregate (SA) provides an innovative experimental approach to monitor stress on concrete. The principle of SA-based concrete seismic stress monitoring is based on the assumption that concrete stress can be reliably predicted by the average output voltages of limited SAs with an acceptable margin of error. In this study, the meso-scale randomness of concrete was evaluated throughout the overall stress range of concrete and the influence of different load paths was considered. Four cylindrical specimens of normal strength concrete were embedded with a total of 24 SAs. The SA output sensitivity curve in the paths of loading–unloading with different amplitudes and monotonic loading up to failure was obtained. Monitoring errors were analyzed during pre- and post-peak stages from the experimental results. This research suggests that SA-based concrete seismic stress monitoring for normal strength concrete is reliable.

  1. Process-based image analysis for agricultural mapping: A case study in Turkgeldi region, Turkey

    Science.gov (United States)

    Damla Uca Avci, Z.; Sunar, Filiz

    2015-10-01

    The need for timely, accurate, and interoperable geospatial information is steadily increasing. In this context, process-based image processing systems will be the initial segment for future's automatic systems. A process-based system is believed to be a good approach for agricultural purpose because agricultural activities are carried out according to a periodic (annual) cycle. Therefore, a process-based image analysis procedure was designed for routine crop classification for an agricultural region in Kırklareli, Turkey. The process tree developed uses a multi-temporal image data set as an input and gives the final crop classification as an output by using an incremental rule set. The test data set was composed of five images of Satellite Pour l'Observation de la Terre 4 (SPOT 4) data acquired in 2007. Basically, image objects were first extracted and then classified. A rule set was structured depending on class definitions. A decision-based process was executed and formed a multilevel image classification system. The final classification was obtained by merging classes from the appropriate levels where they were extracted. To evaluate the success of the application the accuracy of the classification was assessed. The overall accuracy and kappa index of agreement was found to be 80% and 0.78, respectively. At the end of the study, problems of segmentation and classification operations were discussed and solution approaches were outlined. To assess the process in terms of its scope for automation, the efficiency and success of the rule set were also discussed.

  2. Challenges With Manual-Based Multimodal Psychotherapy for People With Alzheimer's Disease: A Case Study.

    Science.gov (United States)

    Tonga, Johanne Bjoernstad; Karlsoeen, Bente Brekne; Arnevik, Espen Ajo; Werheid, Katja; Korsnes, Maria S; Ulstein, Ingun Dina

    2016-06-01

    Earlier detection of dementia requires increased knowledge of how to help people in the early stages of dementia. However, few studies have focused on how psychotherapy should be adapted to improve the outcome of therapy for people with Alzheimer's disease. The aims of the present study were to identify and to explore possible obstacles encountered during the use of manual-based psychotherapy for people with early-stage Alzheimer's disease. The study found that individual adaptations to the treatment manual were necessary, particularly the modification of memory aids in order to adapt them to patients' functional level and previous experience with modern technology. In addition, caregivers were essential for both treatment and homework completion, while reduced awareness constituted an obstacle for adherence to the manual. PMID:26385947

  3. Gender Differences in Neuropsychological Performance across Psychotic Disorders – a Multi-Centre Population Based Case-Control Study

    OpenAIRE

    Zanelli, Jolanta; Morgan, Kevin; Dazzan, Paola; Morgan, Craig; Russo, Manuela; Pilecka, Izabela; Fearon, Paul; Demjaha, Arsime; Doody, Gill A.; Jones, Peter B.; Murray, Robin M; Reichenberg, Abraham

    2013-01-01

    Background Patients with schizophrenia and other psychoses exhibit a wide range of neuropsychological deficits. An unresolved question concerns whether there are gender differences in cognitive performance. Methods Data were derived from a multi-centre population based case-control study of patients with first-episode psychosis. A neuropsychological test battery was administered to patients with a diagnosis of schizophrenia or schizoaffective disorder (N=70, 36% females), bipolar/mania (N=34,...

  4. Measurement Error Correction in Exploiting Gene-Environment Independence in Family-Based Case-Control Studies.

    OpenAIRE

    Guolo, Annamaria

    2009-01-01

    Family-based case-control designs are commonly used in epidemiological studies for evaluating the role of genetic susceptibility and environmental exposure to risk factors in the etiology of rare diseases. Within this framework, it is often reasonable to assume genetic susceptibility and environmental exposure being conditionally independent of each other within families in the source population. We focus on this setting to consider the common situation of measurement error aecting the assess...

  5. Selection and ranking of occupational safety indicators based on fuzzy AHP: A case study in road construction companies

    OpenAIRE

    Janackovic, Goran Lj.; Suzana M. Savic; Stankovic, Miomir S.

    2013-01-01

    This paper presents the factors, performance, and indicators of occupational safety, as well as a method to select and rank occupational safety indicators based on the expert evaluation method and the fuzzy analytic hierarchy process (fuzzy AHP). A case study is done on road construction companies in Serbia. The key safety performance indicators for the road construction industry are identified and ranked according to the results of a survey that included experts who assessed occupational saf...

  6. CSR as a Tool to Prevent Gender-Based Discrimination. A Case Study of the Textile Export Industry in India

    OpenAIRE

    Svedevall, Ida

    2015-01-01

    This thesis examines the ability of CSR as a tool in the efforts to reduce gender based discrimination in the textile industry in the Delhi area in India. This research focuses on the CSR work programs undertaken by foreign entities using the case study of the company Lindex. Given that discrimination occurs daily facilitated by embedded cultural structures this research questions how, and if, CSR interventions can be successful in address these underlying issues. This research draws on exist...

  7. Applying computer-based simulation to energy auditing: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Y. [Department of Construction Management, College of Engineering and Computing, Engineering Centre, Florida International University, Miami, FL (United States)

    2006-07-01

    Through a case study, this research explores an approach, which uses computer simulation technology, to evaluate different energy conservation alternatives and to assist facility managers to select reliable and feasible solutions. The subject facility is located in the Southeast region of the United States. One of the major challenges and operation goals of the General Services Administration, who manages the facility, is for that facility to achieve the Energy Star designation. However, due to the complexity of the facility, the requirements from building occupants, as well as other difficulties, finding a path for optimizing the operation of the facility in order to achieve the Energy Star designation is not always easy. This project uses eQuest, a simulation software tool, to create a 'virtual environment', in which the operations of the HVAC (heating ventilation air-conditioning) system and the lighting of the facility are studied. Subsequently, recommendations initially made by experts through traditional energy audit approaches are evaluated in the 'virtual environment' in order to determine the best solution to achieve the goal of the facility managers. This paper discusses major aspects of the project, including the challenges, the values and the limitations of applying computer simulation techniques in such a facility with complicated structural, occupancy and operation features. (author)

  8. Applying computer-based simulation to energy auditing: a case study

    Energy Technology Data Exchange (ETDEWEB)

    Yimin Zhu [Florida International University, Miami, FL (United States). Dept. of Construction Management

    2006-05-15

    Through a case study, this research explores an approach, which uses computer simulation technology, to evaluate different energy conservation alternatives and to assist facility managers to select reliable and feasible solutions. The subject facility is located in the Southeast region of the United States. One of the major challenges and operation goals of the General Services Administration, who manages the facility, is for that facility to achieve the Energy Star designation. However, due to the complexity of the facility, the requirements from building occupants, as well as other difficulties, finding a path for optimizing the operation of the facility in order to achieve the Energy Star designation is not always easy. This project uses eQuest, a simulation software tool, to create a ''virtual environment'', in which the operations of the HVAC (heating ventilation air-conditioning) system and the lighting of the facility are studied. Subsequently, recommendations initially made by experts through traditional energy audit approaches are evaluated in the ''virtual environment'' in order to determine the best solution to achieve the goal of the facility managers. This paper discusses major aspects of the project, including the challenges, the values and the limitations of applying computer simulation techniques in such a facility with complicated structural, occupancy and operation features. (author)

  9. An investigation of Forex market efficiency based on detrended fluctuation analysis: A case study for Iran

    Science.gov (United States)

    Abounoori, Esmaiel; Shahrazi, Mahdi; Rasekhi, Saeed

    2012-06-01

    The efficient market hypothesis (EMH) states that asset prices fully reflect all available information. As a result, speculators cannot predict the future behavior of asset prices and earn excess profits at least after adjusting for risk. Although initial tests of the EMH were performed on stock market data, the EMH was soon applied to other markets including foreign exchange (FX). This study uses the detrended fluctuation analysis (DFA) technique to test 01:12:2005-18:04:2010 Iranian Rial/US Dollar exchange rate time series data to see if it can be explained by the weak form of the EMH. Moreover, to determine changes in the degree of inefficiency over time, the whole period has been divided into four subperiods. The study shows that the Iranian Forex market (the Rial/Dollar case) is weak-form inefficient over the whole period and in each of the subperiods. However, the degree of inefficiency is not constant over time. The findings suggest that profitable risk-adjusted trades could be made using past data.

  10. Integrative dynamic therapy for bulimia nervosa: An evidence-based case study.

    Science.gov (United States)

    Richards, Lauren K; Shingleton, Rebecca M; Goldman, Rachel; Siegel, Deborah; Thompson-Brenner, Heather

    2016-06-01

    Both cognitive-behavioral therapy (CBT) and psychodynamic psychotherapy are commonly used to treat eating disorders. To further investigate the effectiveness of integrative dynamic therapy (IDT) for bulimia nervosa (BN), our research group undertook a randomized, controlled pilot study comparing IDT with CBT for BN. The case described here was selected from a sample of N = 38 female patients with the symptoms of BN who enrolled in the study. IDT incorporated aspects of the first 4-week stage of CBT, including psychoeducation, self-monitoring, and regular eating. Subsequently, the treatment focused on emotional expression, emotion regulation (defenses), intrapsychic conflict, and interpersonal relationships. The objectives of the report are to demonstrate the effectiveness of an integrative approach to the treatment of eating disorders to address the symptoms of BN and personality issues using pre-, mid-, and posttreatment data, and to illustrate the patient and clinician reactions to each approach to treatment using excerpts from session transcripts and alliance data. (PsycINFO Database Record PMID:27267504

  11. LIFE CYCLE ASSESSMENT FOR OIL PALM BASED PLYWOOD: A GATE-TO-GATE CASE STUDY

    Directory of Open Access Journals (Sweden)

    M. Shamim Ahmad

    2014-01-01

    Full Text Available Life Cycle Assessment (LCA is an important tool for identifying potential environmental impacts associated with the production of palm based plywood. This study is to make available the life cycle inventory for gate-to-gate data so that the environmental impact posed by oil palm based plywood production can be assessed. Conducting an LCA on the palm based plywood that are derived from the wastes of the oil palm industry is a first step towards performing green environmental product. Therefore.establishing baseline information for the complete environmental profile of the palm oil plywood is essential. Data from this study on the environmental impact for the production of palm plywood would help to develop sustainable palm plywood product. The results will provide information to identify ways and measures to reduce the environmental impacts. Most foreground data were collected directly from numbers oil palm plywood factories which represent 40% of the palm plywood industry in Peninsular Malaysia. Data gaps were filled by information obtained through questionnaires which were developed specifically for data collection, literature, public database or further calculated from obtained data. The outputs and inputs from production activities were quantified on the basis of functional unit of production of 1 m3from different types of oil palm based plywood i.e., Moisture Resistant (MR, Weather Boiling Proof (WBP Grade 1 and Weather Boiling Proof (WBP Grade 2. The life cycle impact assessment was carried out using SimaPro 7.1 software and the eco-indicator 99 methodology. The weighting results of LCA for the production of 1 cubic meter of oil palm based plywood showed significant impact in descending order i.e., fossil fuel, respiratory inorganic and climate change. The most significant process contributing to these environmental impacts came from the production and usage of adhesives, transportation of oil palm trunks from plantation to factory and

  12. Gene transfection in high serum levels: case studies with new cholesterol based cationic gemini lipids.

    Directory of Open Access Journals (Sweden)

    Santosh K Misra

    Full Text Available BACKGROUND: Six new cationic gemini lipids based on cholesterol possessing different positional combinations of hydroxyethyl (-CH2CH2OH and oligo-oxyethylene -(CH2CH2On- moieties were synthesized. For comparison the corresponding monomeric lipid was also prepared. Each new cationic lipid was found to form stable, clear suspensions in aqueous media. METHODOLOGY/PRINCIPAL FINDINGS: To understand the nature of the individual lipid aggregates, we have studied the aggregation properties using transmission electron microscopy (TEM, dynamic light scattering (DLS, zeta potential measurements and X-ray diffraction (XRD. We studied the lipid/DNA complex (lipoplex formation and the release of the DNA from such lipoplexes using ethidium bromide. These gemini lipids in presence of a helper lipid, 1, 2-dioleoyl phophatidyl ethanol amine (DOPE showed significant enhancements in the gene transfection compared to several commercially available transfection agents. Cholesterol based gemini having -CH2-CH2-OH groups at the head and one oxyethylene spacer was found to be the most effective lipid, which showed transfection activity even in presence of high serum levels (50% greater than Effectene, one of the potent commercially available transfecting agents. Most of these geminis protected plasmid DNA remarkably against DNase I in serum, although the degree of stability was found to vary with their structural features. CONCLUSIONS/SIGNIFICANCE: -OH groups present on the cationic headgroups in combination with oxyethylene linkers on cholesterol based geminis, gave an optimized combination of new genera of gemini lipids possessing high transfection efficiency even in presence of very high percentage of serum. This property makes them preferential transfection reagents for possible in vivo studies.

  13. Self-healing of lime based mortars: Microscopy observations on case studies

    OpenAIRE

    Lubelli, B.; Nijland, T.G.; Hees, R.P.J. van

    2011-01-01

    Lime mortars have, up to a certain extent, a self-healing capacity which may contribute to their durability. Self-healing in lime mortars consists of a process of dissolution, transport and re-precipitation of calcium compounds to heal cracks and fissures. The spontaneous occurrence of self-healing in lime-based mortars is a well known phenomenon; to date, however, little research has been done on its occurrence in the practice. This study aims at gaining a better understanding of the self-he...

  14. Web-based ERP systems: the new generation : case study: mySAP ERP

    OpenAIRE

    Gomis, Marie-Joseph

    2007-01-01

    With the proliferation of Internet, ERP systems like all the domains of Information Technology have known an important evolution. This final thesis project is a study about the evolution of ERP systems, more precisely about their migration to the Web giving birth to a new generation of systems: the Web-Based or Web-enabled ERP systems. This migration to the Web is justified by the difficulty of making possible the communication between partner’s legacy systems and the organizations’ ERP syste...

  15. Case Study: Evidence-Based Interventions Enhancing Diabetic Foot Care Behaviors among Hospitalized DM Patients

    Directory of Open Access Journals (Sweden)

    Titis Kurniawan

    2011-01-01

    Full Text Available Background: Improving diabetic patients’ foot care behaviors is one of the most effective strategies in minimizing diabetic foot ulceration and its further negative impacts, either in diabetic hospitalized patients or outpatients.Purpose: To describe foot care knowledge and behaviors among hospitalized diabetic patients, to apply selected foot care knowledge and behaviors improvement evidence, and to evaluate its effectiveness.Method: Four diabetic patients who were under our care for at least three days and could communicate in Thai language were selected from a surgical ward in a university hospital. The authors applied educational program based on patients’ learning needs, provided diabetic foot care leaflet, and assisted patients to set their goal and action plans. In the third day of treatment, we evaluated patients’ foot care knowledge and their goal and action plan statements in improving foot care behaviors.Result: Based on the data collected among four hospitalized diabetic patients, it was shown that all patients needed foot care behaviors improvement and the educational program improved hospitalized patients’ foot care knowledge and their perceived foot care behaviors. The educational program that combined with goal setting and action plans method was easy, safe, and seemed feasibly applicable for diabetic hospitalized patients.Conclusion: The results of this study provide valuable information for improvement of hospitalized diabetic patients’ foot care knowledge and behaviors. The authors recommend nurses to use this evidence-based practice to contribute in improving the quality of diabetic care.Keywords: Intervention, diabetic foot care, hospitalized diabetic patients

  16. Dietary pattern and risk of hodgkin lymphoma in a population-based case-control study.

    Science.gov (United States)

    Epstein, Mara M; Chang, Ellen T; Zhang, Yawei; Fung, Teresa T; Batista, Julie L; Ambinder, Richard F; Zheng, Tongzhang; Mueller, Nancy E; Birmann, Brenda M

    2015-09-01

    Classic Hodgkin lymphoma (cHL) has few known modifiable risk factors, and the relationship between diet and cHL risk is unclear. We performed the first investigation of an association between dietary pattern and cHL risk in 435 cHL cases and 563 population-based controls from Massachusetts and Connecticut (1997-2000) who completed baseline diet questionnaires. We identified 4 major dietary patterns ("vegetable," "high meat," "fruit/low-fat dairy," "desserts/sweets") using principal components analysis. We computed multivariable odds ratios and 95% confidence intervals for associations of dietary pattern score (quartiles) with younger-adult (age desserts/sweets was associated with younger-adult (odds ratio(quartile 4 vs. quartile 1) = 1.60, 95% confidence interval: 1.05, 2.45; Ptrend = 0.008) and EBV-negative, younger-adult (odds ratio = 2.11, 95% confidence interval: 1.31, 3.41; Ptrend = 0.007) cHL risk. A high meat diet was associated with older-adult (odds ratio = 3.34, 95% confidence interval: 1.02, 10.91; Ptrend = 0.04) and EBV-negative, older-adult (odds ratio = 4.64, 95% confidence interval: 1.03, 20.86; Ptrend = 0.04) cHL risk. Other dietary patterns were not clearly associated with cHL. We report the first evidence for a role of dietary pattern in cHL etiology. Diets featuring high intake of meat or desserts and sweets may increase cHL risk. PMID:26182945

  17. Exploring users’ within-site navigation behavior:A case study based on clickstream data

    Institute of Scientific and Technical Information of China (English)

    Tingting; JIANG; Yu; CHI; Wenrui; JIA

    2014-01-01

    Purpose:The goal of our research is to suggest specific Web metrics that are useful for evaluating and improving user navigation experience on informational websites.Design/methodology/approach:We revised metrics in a Web forensic framework proposed in the literature and defined the metrics of footprint,track and movement.Data were obtained from user clickstreams provided by a real estate site’s administrators.There were two phases of data analysis with the first phase on navigation behavior based on user footprints and tracks,and the second phase on navigational transition patterns based on user movements.Findings:Preliminary results suggest that the apartment pages were heavily-trafficked while the agent pages and related information pages were underused to a great extent.Navigation within the same category of pages was prevalent,especially when users navigated among the regional apartment listings.However,navigation of these pages was found to be inefficient.Research limitations:The suggestions for navigation design optimization provided in the paper are specific to this website,and their applicability to other online environments needs to be verified.Preference predications or personal recommendations are not made during the current stage of research.Practical implications:Our clickstream data analysis results offer a base for future research.Meanwhile,website administrators and managers can make better use of the readily available clickstream data to evaluate the effectiveness and efficiency of their site navigation design.Originality/value:Our empirical study is valuable to those seeking analysis metrics for evaluating and improving user navigation experience on informational websites based on clickstream data.Our attempts to analyze the log file in terms of footprint,track and movement will enrich the utilization of such trace data to engender a deeper understanding of users’within-site navigation behavior.

  18. Contracting and Procurement for Evidence-Based Interventions in Public-Sector Human Services: A Case Study.

    Science.gov (United States)

    Willging, Cathleen E; Aarons, Gregory A; Trott, Elise M; Green, Amy E; Finn, Natalie; Ehrhart, Mark G; Hecht, Debra B

    2016-09-01

    Sustainment of evidence-based interventions (EBIs) in human services depends on the inner context of community-based organizations (CBOs) that provide services and the outer context of their broader environment. Increasingly, public officials are experimenting with contracting models from for-profit industries to procure human services. In this case study, we conducted qualitative interviews with key government and CBO stakeholders to examine implementation of the Best Value-Performance Information Procurement System to contract for EBIs in a child welfare system. Findings suggest that stakeholder relationships may be compromised when procurement disregards local knowledge, communication, collaboration, and other factors supporting EBIs and public health initiatives. PMID:26386977

  19. Intelligence-based automatic detection and classification of ground collapses using object-based image analysis method: a case study in Paitan of Pearl River delta

    Science.gov (United States)

    Dou, Jie; Zheng, Xiao-zhan; Qian, Jun-ping; Liu, Rui-hua; Wu, Qi-tao

    2009-10-01

    In this paper, a new method is proposed by applying case-based reasoning technique for detecting the ground collapses. The study demonstrates that the high resolution remote sensing images are suitable for monitoring the ground collapses in the study area with karst relief. With the help of object-based image analysis method, the generic algorithm (GA) for optimizing the spatial, shape, spectral, hierarchy and textural features was used in the multi-scale image segmentation with the good fitness value, and then the case library was built for detecting the collapse. The case library is reusable for place-independent detection. The proposed method has been tested in the Pearl River Delta in south China. The result of ground-collapse detection is well.

  20. Vertebral Angiosarcoma. Case Study.

    Science.gov (United States)

    Guzik, Grzegorz

    2015-01-01

    Bone angiosarcomas, especially vertebral angiosarcomas, are very rare. There are no studies based on large clinical samples in the literature, and only a few single case reports can be found. The symptoms of the disease are not specific. It is usually detected incidentally or at a late stage when pathological vertebral fractures or neurological complications occur. Diagnostic imaging and history help to recognize the tumour behind the symptoms, but do not allow accurate clinical diagnosis. The basis for a diagnosis is the histopathological examination supported by immunohistochemistry (IHC) assays. The case of a 26-year-old woman with an angiosarcoma involving the eighth thoracic vertebra we report reflects diagnostic problems adversely affecting the efficacy and accuracy of treatment offered to patients. The patient underwent three surgeries of the spine, including two biopsies. A needle biopsy did not provide sufficient information for the diagnosis. An open excisional biopsy, which at the same time temporarily reduced neurological deficits in the patient, was the only chance to obtain an accurate diagnosis. The third surgery was posterior decompression of the spinal cord due to the rapidly escalating paraparesis. It was not until 8 weeks later that the final diagnosis was established. At that time, the patient could not be qualified for any supplementary treatment. The patient died in hospital 6 months after the onset of disease. PMID:26468177

  1. Documentation of Cultural Heritages Using a GIS Based Information and Management System; Case Study of Safranbolu

    Science.gov (United States)

    Seker, D. Z.; Alkan, M.; Kutoglu, S. S.; Akcin, H.

    2010-12-01

    Documentation of the cultural heritage sites is extremely important for monitoring and preserves them from natural disasters and human made activities. Due to its very rich historical background from the first human settlements in Catalhoyuk and Alacahoyuk and civilizations such as Byzantine, Seljuk and Ottoman, there are lots of cultural heritage sites in Turkey. 3D modeling and recording of historical buildings using modern tools and techniques in several locations of Turkey have been conducted and still continuing. The nine cultural sites in Turkey are included in the protection list of UNESCO as cultural heritage and one of them is the township of Safranbolu, which is the one of the most outstanding example of the traditional Turkish Architecture and also unique itself in terms of conservation of the human settlement in their authentic environmental motif up till now. In this study outcomes and further studies of a research project related to study area which is supported by the Turkish National Research Center (TUBITAK) with the project number 106Y157, will be presented in details. The basic aim of the study is development a GIS based information and management system for the city of Safranbolu. All historical buildings which are registered are assigned with the database. 3D modeling some of the selected building among the buildings which are registered as historical monuments using different data comes from different sources similar to their original constructions were realized and then it will be distributed via internet by a web-based information system designed during the project. Also some of the buildings were evaluated using close range photogrammetric technique to obtain their façade reliefs, were also assigned with the database. Designed database consists of 3D models, locations, historical information, cadastral and land register data of the selected buildings together with the other data collected during the project related to buildings. Using this

  2. A multi-site, randomized study of strengths-based case management with substance-abusing parolees.

    Science.gov (United States)

    Prendergast, Michael; Frisman, Linda; Sacks, Joann Y; Staton-Tindall, Michele; Greenwell, Lisa; Lin, Hsiu-Ju; Cartier, Jerry

    2011-09-01

    OBJECTIVES: To test whether strengths-based case management provided during an inmate's transition from incarceration to the community increases participation in community substance abuse treatment, enhances access to needed social services, and improves drug use, crime, and HIV risk outcomes. METHODS: In a multi-site trial, inmates (men and women) in four states (n = 812) were randomly assigned (within site) to receive either Transitional Case Management (TCM group), based on strengths-based principles, or standard parole services (SR group). Data were collected at baseline and at 3 and 9 months following release from prison. Analyses compared the two groups with respect to services received and to drug use, crime, and HIV risk behavior outcomes. RESULTS: There were no significant differences between parolees in the TCM group and the SR group on outcomes related to participation in drug abuse treatment, receipt of social services, or drug use, crime, and HIV risk behaviors. For specific services (e.g., residential treatment, mental health), although significant differences were found for length of participation or for number of visits, the number of participants in these services was small and the direction of effect was not consistent. CONCLUSION: In contrast to positive findings in earlier studies of strengths-based case management with mental-health and drug-abuse clients, this study found that case management did not improve treatment participation or behavioral outcomes for parolees with drug problems. The discussion includes possible reasons for the findings and suggestions for modifications to the intervention that could be addressed in future research. PMID:21949490

  3. EXPLAINING THE AUDIT RISK AND ITS COMPONENTS: A COMPARATIVE CASE-STUDY BASED ON AUDIT REPORTS

    OpenAIRE

    ALINA VOICULESCU; SORINA SIMONA BUMBESCU

    2014-01-01

    The players activating in the post-recession business environment have to and begin to be more and more prudent and attentive to any sign of human errors, uncertainty, lack of objectivity, attempt of fraud which may occur when financial statements are prepared, in their own case or in the case of their trade clients/suppliers, debtors, business partners, in general. Auditors thus became the mediators between the producers and the users of accountant information, using their hi...

  4. Daytime sea fog retrieval based on GOCI data: a case study over the Yellow Sea.

    Science.gov (United States)

    Yuan, Yibo; Qiu, Zhongfeng; Sun, Deyong; Wang, Shengqiang; Yue, Xiaoyuan

    2016-01-25

    In this paper, a new daytime sea fog detection algorithm has been developed by using Geostationary Ocean Color Imager (GOCI) data. Based on spectral analysis, differences in spectral characteristics were found over different underlying surfaces, which include land, sea, middle/high level clouds, stratus clouds and sea fog. Statistical analysis showed that the Rrc (412 nm) (Rayleigh Corrected Reflectance) of sea fog pixels is approximately 0.1-0.6. Similarly, various band combinations could be used to separate different surfaces. Therefore, three indices (SLDI, MCDI and BSI) were set to discern land/sea, middle/high level clouds and fog/stratus clouds, respectively, from which it was generally easy to extract fog pixels. The remote sensing algorithm was verified using coastal sounding data, which demonstrated that the algorithm had the ability to detect sea fog. The algorithm was then used to monitor an 8-hour sea fog event and the results were consistent with observational data from buoys data deployed near the Sheyang coast (121°E, 34°N). The goal of this study was to establish a daytime sea fog detection algorithm based on GOCI data, which shows promise for detecting fog separately from stratus. PMID:26832463

  5. Organic agriculture in the municipality of Alta Floresta-MT: case study on family based properties

    Directory of Open Access Journals (Sweden)

    Inês Caroline de Lima Proença

    2016-08-01

    Full Text Available Family farming has distinct characteristics in their organization and reproduction, such as the use of labor, family labor, the smallest territorial dimension of the plant and crop diversity. Organic agriculture has great potential for family farms, establishing more harmonious relationships between natural ecosystems and agricultural activities. In this context, this paper aims to study five units of organic farming family based in the municipality of Alta Floresta, state of Mato Grosso, making the general characterization of it and trying to identify the reality and the difficulties faced by these farmers. Data were made from semi-structured interviews and observation. It was found that the lack of technical assistance, the lack of access to rural credit facilities and lack of family labor are limiting factors that directly interfere with the management of agroecosystems. Furthermore, the great diversity of species managed is a key success factor in seeking and maintaining the stability of agroecosystems.

  6. Subtle trap recognition based on seismic sedimentology-A case study from Shengli Oilfield

    Institute of Scientific and Technical Information of China (English)

    Huang Handong; Zhang Ruwei; Luo Qun; Zhao Di; Peng Yongmin

    2009-01-01

    Seismic sedimentology is the study of sedimentary rocks and facies using seismic data. However, often the sedimentary body features can't be described quantitatively due to the limit of seismic resolution. High resolution inversion offsets this limitation and is applied to seismic sedimentology to identify subtle traps under complex geologic conditions, thereby widening the applicable range of seismic sedimentology. In this paper, based on seismic sedimentology, seismic phase-controlled nonlinear random inversion is used to predict the sandy conglomerate reservoir of Es3 in the Chezhen depression in Shengli Oilfield. Thickness and sedimentary microfacies maps of sandy conglomerate bodies in several stages are presented and several subtle traps were predicted and verified by drilling.

  7. Systems thinking tools as applied to community-based participatory research: a case study.

    Science.gov (United States)

    BeLue, Rhonda; Carmack, Chakema; Myers, Kyle R; Weinreb-Welch, Laurie; Lengerich, Eugene J

    2012-12-01

    Community-based participatory research (CBPR) is being used increasingly to address health disparities and complex health issues. The authors propose that CBPR can benefit from a systems science framework to represent the complex and dynamic characteristics of a community and identify intervention points and potential "tipping points." Systems science refers to a field of study that posits a holistic framework that is focused on component parts of a system in the context of relationships with each other and with other systems. Systems thinking tools can assist in intervention planning by allowing all CBPR stakeholders to visualize how community factors are interrelated and by potentially identifying the most salient intervention points. To demonstrate the potential utility of systems science tools in CBPR, the authors show the use of causal loop diagrams by a community coalition engaged in CBPR activities regarding youth drinking reduction and prevention. PMID:22467637

  8. Generalized functional linear models for gene-based case-control association studies.

    Science.gov (United States)

    Fan, Ruzong; Wang, Yifan; Mills, James L; Carter, Tonia C; Lobach, Iryna; Wilson, Alexander F; Bailey-Wilson, Joan E; Weeks, Daniel E; Xiong, Momiao

    2014-11-01

    By using functional data analysis techniques, we developed generalized functional linear models for testing association between a dichotomous trait and multiple genetic variants in a genetic region while adjusting for covariates. Both fixed and mixed effect models are developed and compared. Extensive simulations show that Rao's efficient score tests of the fixed effect models are very conservative since they generate lower type I errors than nominal levels, and global tests of the mixed effect models generate accurate type I errors. Furthermore, we found that the Rao's efficient score test statistics of the fixed effect models have higher power than the sequence kernel association test (SKAT) and its optimal unified version (SKAT-O) in most cases when the causal variants are both rare and common. When the causal variants are all rare (i.e., minor allele frequencies less than 0.03), the Rao's efficient score test statistics and the global tests have similar or slightly lower power than SKAT and SKAT-O. In practice, it is not known whether rare variants or common variants in a gene region are disease related. All we can assume is that a combination of rare and common variants influences disease susceptibility. Thus, the improved performance of our models when the causal variants are both rare and common shows that the proposed models can be very useful in dissecting complex traits. We compare the performance of our methods with SKAT and SKAT-O on real neural tube defects and Hirschsprung's disease datasets. The Rao's efficient score test statistics and the global tests are more sensitive than SKAT and SKAT-O in the real data analysis. Our methods can be used in either gene-disease genome-wide/exome-wide association studies or candidate gene analyses. PMID:25203683

  9. Citation, Curation, and Preservation of Scientific Data: A Case Study Based on Lidar Topographic Data

    Science.gov (United States)

    Baru, C.; Crosby, C. J.; Kozbial, A.; Minor, D.

    2011-12-01

    Data citation, curation, and preservation are intrinsic to the use of digital data in scientific research. In the internet-based, digital world, citations are not only to peer reviewed research publications, but also to the data that was used in the corresponding scientific analysis, leading to the issue of data provenance-which data are worth preserving for citation? Should all intermediate datasets be preserved, or only the initial and final data? Should the data products be preserved or only the processes used to derive the products, or both? Using examples from the NSF-funded OpenTopography project, which distributes high-resolution lidar topography data and provides on-demand data processing, we will explore these issues of citation, curation, and preservation. A set of data products can typically be associated with a single lidar dataset,, including "raw" data files from the laser scanner, GPS and IMU instruments; processed and classified point clouds; derived gridded data products, such as digital elevation models; and, other subsequent products used in downstream visualization and analyses. We will describe the data curation services that have been defined as part of UC San Diego's Research Cyberinfrastructure and how they might be applied to the topography use case. Curation services at UC San Diego are provided jointly by staff of the UC San Diego Libraries and the San Diego Supercomputer Center (SDSC). The Libraries provide curatorial oversight and bibliographic control and integration services. SDSC staff provide the back-end technology services needed to actively store and maintain data. Staff from both organizations provide metadata services necessary to ensure that data remain discoverable and accessible. Because data are subject to loss caused by environmental, organizational, or technological disruptions, another layer of service is required that stores exact duplicates of the data offsite. This important service will be modeled on Chronopolis, a

  10. Prevalence and Risk Factors for Diabetic Lower Limb Amputation: A Clinic-Based Case Control Study

    Science.gov (United States)

    Rodrigues, Beverly T.; Vangaveti, Venkat N.

    2016-01-01

    Objective. The aim of the study was to evaluate the prevalence of and risk factors for lower limb amputation in a specialist foot clinic-based setting. Methods. A retrospective quantitative study was conducted, using clinical and biochemical profiles of diabetic foot patients attending the High Risk Foot Clinic at The Townsville Hospital, Australia, between January 1, 2011, and December 31, 2013. Results. The total study sample included 129 subjects, comprising 81 males and 48 females with M : F ratio of 1.7 : 1. Twenty-three subjects were Indigenous Australians, representing 17.8% of the study population. The average age of the cohort was 63.4 years ± 14.1 years [CI 90.98–65.89]. Lower limb amputation was identified as a common and significant outcome (n = 44), occurring in 34.1%, more commonly amongst the Indigenous Australians (56.5% versus 29.2%; p = 0.94, OR 0.94). Risk factors most closely associated with amputation included diabetic retinopathy (p = 0.00, OR 4.4), coronary artery bypass graft (CABG) surgery (p = 0.01, OR 4.1), Charcot's arthropathy (p = 0.01, OR 2.9), and Indigenous ethnicity (p = 0.01, OR 3.4). Although average serum creatinine, corrected calcium, and glycosylated haemoglobin A1c (Hba1c) levels were higher amongst amputees they were statistically insignificant. Conclusions. Lower limb amputation is a common outcome and linked to ethnicity and neurovascular diabetic complications amongst subjects with diabetic foot ulcer. Further research is needed to identify why risk of lower limb amputation seems to differ according to ethnicity.

  11. Adaptation Knowledge Discovery from a Case Base

    OpenAIRE

    D'Aquin, Mathieu; Badra, Fadi; Lafrogne, Sandrine; Lieber, Jean; Napoli, Amedeo; Szathmary, Laszlo

    2006-01-01

    In case-based reasoning, the adaptation step depends in general on domain-dependent knowledge, which motivates studies on adaptation knowledge acquisition (AKA). CABAMAKA is an AKA system based on principles of knowledge discovery from databases. This system explores the variations within the case base to elicit adaptation knowledge. It has been successfully tested in an application of case-based decision support to breast cancer treatment.

  12. Risk assessment of tobacco, alcohol and diet in cancers of base tongue and oral tongue--a case control study.

    OpenAIRE

    Rao D; Desai P

    1998-01-01

    This is a retrospective case-control study of male tongue cancer patients seen at Tata memorial Hospital, Bombay, during the years 1980-84. The purpose of the study was to identify the association of tobacco, alcohol, diet and literacy status with respect to cancers of two sub sites of tongue namely anterior portion of the tongue (AT) (ICD 1411-1414) and base of the tongue (BT) (ICD 1410). There were 142 male AT patients and 495 BT patients interviewed during the period. 635 interviewed male ...

  13. HYDROGEOLOGIC CASE STUDIES

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  14. Can Hawaii Meet Its Renewable Fuel Target? Case Study of Banagrass-Based Cellulosic Ethanol

    Directory of Open Access Journals (Sweden)

    Chinh Tran

    2016-08-01

    Full Text Available Banagrass is a biomass crop candidate for ethanol production in the State of Hawaii. This study examines: (i whether enough banagrass can be produced to meet Hawaii’s renewable fuel target of 20% highway fuel demand produced with renewable sources by 2020 and (ii at what cost. This study proposes to locate suitable land areas for banagrass production and ethanol processing, focusing on the two largest islands in the state of Hawaii—Hawaii and Maui. The results suggest that the 20% target is not achievable by using all suitable land resources for banagrass production on both Hawaii and Maui. A total of about 74,224,160 gallons, accounting for 16.04% of the state’s highway fuel demand, can be potentially produced at a cost of $6.28/gallon. Lower ethanol cost is found when using a smaller production scale. The lowest cost of $3.31/gallon is found at a production processing capacity of about 9 million gallons per year (MGY, which meets about 2% of state demand. This cost is still higher than the average imported ethanol price of $3/gallon. Sensitivity analysis finds that it is possible to produce banagrass-based ethanol on Hawaii Island at a cost below the average imported ethanol price if banagrass yield increases of at least 35.56%.

  15. Technology Solutions Case Study: Apartment Compartmentalization with an Aerosol-Based Sealing Process

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-07-01

    Air sealing of building enclosures is a difficult and time-consuming process. Current methods in new construction require laborers to physically locate small and sometimes large holes in multiple assemblies and then manually seal each of them. This research study by Building America team Consortium for Advanced Residential Buildings demonstrated the automated air sealing and compartmentalization of buildings through the use of an aerosolized sealant developed by the Western Cooling Efficiency Center at University of California Davis. CARB demonstrated this new technology application in a multifamily building in Queens, NY. The effectiveness of the sealing process was evaluated by three methods: air leakage testing of overall apartment before and after sealing, point-source testing of individual leaks, and pressure measurements in the walls of the target apartment during sealing. Aerosolized sealing was successful by several measures in this study. Many individual leaks that are labor-intensive to address separately were well sealed by the aerosol particles. In addition, many diffuse leaks that are difficult to identify and treat were also sealed. The aerosol-based sealing process resulted in an average reduction of 71% in air leakage across three apartments and an average apartment airtightness of 0.08 CFM50/SF of enclosure area.

  16. Optimization of a forest harvesting set based on the Queueing Theory: Case study from Karelia

    Directory of Open Access Journals (Sweden)

    Shegelman Ilya

    2015-12-01

    Full Text Available The modern technological process of timber harvesting is a complex system both technically and organizationally. Nowadays, the study of such systems and improvement of their efficiency is impossible without the use of mathematical modeling methods. The paper presents the methodology for the optimization of logging operations based on the queueing theory. We show the adapted queueing model, which characterizes the process of logging with the use of a harvesting set consisting of harvesters and forwarders. We also present the experimental verification of the designated model that confirmed mode’s adequacy. The analysis of the effectiveness of the investigated harvesting set was conducted and the recommendations for its optimization were drawn. The research was conducted in the Pryazhinsky District in the Republic of Karelia. We showed that significant improvement of operational efficiency of the investigated harvesting set in the study area cannot be done by adjusting separate machine operations (i.e. by reducing the time of operations execution and their steadiness. However, a change in the number of machines allowed significant improvement in the operational efficiency. The most optimal harvesting set design for the experimental area consisted of two harvesters and two forwarders.

  17. Socio-demographic profile and suicidal intent of attempted suicide cases: A hospital based study in West Bengal, India

    Directory of Open Access Journals (Sweden)

    Subhadip Bharati

    2013-04-01

    Full Text Available Background: Suicide is one of the ten major causes of death in India. Suicidal intent score has been found to be a good predictor of a subsequent completed suicide. The present study was conducted to find out the socio-demographic profile and the suicidal intent score of the cases of attempted suicide as well as to determine the association of suicidal intent score with various factors. Methodology: We conducted the present hospital based observational cross sectional study at a rural hospital of Eastern India. 156 admitted cases with history of self-poisoning were interviewed after obtaining the informed consent. Socio-demographic information and suicidal intent score were recorded and analyzed. Results: 55.1% patients were in the age group of below 20 years, 69.2% were females, 58.3% belonged to socioeconomic class V and 17.3% patients were illiterate. 43.6% were students and 28.8% housewives. 17.3% patients had history of suicidal attempts in the past and in 23.1 % cases stress factor was present in the family. Suicidal intent score was medium in 63.5% patients, 10.3% patients had low score and 26.2% had high score. Different factors like age of 20 years and above, male sex, married people, people having addiction habit, previous suicidal attempt, positive family history and stress factors in family increased the suicidal intent score whereas aged less than 20 years, female sex, unmarried people, people having no previous attempt of suicide, negative family history and absence of stress factor in the family decreased the suicidal intent score. Conclusion: The present study highlighted the influencing factors of suicidal intent score based on a hospital set up. A larger community based study with follow up of study subjects is required to get a detailed idea about the influencing factors of suicidal intent score. [Natl J Med Res 2013; 3(2.000: 122-125

  18. Manganese Superoxide Dismutase Polymorphism and Breast Cancer Recurrence: A Danish Population-Based Case-Control Study of Breast Cencer Patients Treated with Cyclophosphamide Epirubicin and 5-Fluororacil

    DEFF Research Database (Denmark)

    Ording, Anne Gulbech; Cronin Fenton, Deirdre; Christensen, Mariann;

    2012-01-01

    Manganese Superoxide Dismutase Polymorphism and Breast Cancer Recurrence: A Danish Population-Based Case-Control Study of Breast Cencer Patients Treated with Cyclophosphamide Epirubicin and 5-Fluororacil......Manganese Superoxide Dismutase Polymorphism and Breast Cancer Recurrence: A Danish Population-Based Case-Control Study of Breast Cencer Patients Treated with Cyclophosphamide Epirubicin and 5-Fluororacil...

  19. Manganese Superoxide Dismtase Polymorphism and Breast Cancer Recurrence: A Danish Population-Based Case-Control Study of Breast Cancer Patients Treated with Cyclophosphamide Epirubicin and 5-fluorouracil

    DEFF Research Database (Denmark)

    Ording, Anne Gulbech; Cronin Fenton, Deirdre; Christensen, Mariann;

    2013-01-01

    Manganese Superoxide Dismtase Polymorphism and Breast Cancer Recurrence: A Danish Population-Based Case-Control Study of Breast Cancer Patients Treated with Cyclophosphamide Epirubicin and 5-fluorouracil......Manganese Superoxide Dismtase Polymorphism and Breast Cancer Recurrence: A Danish Population-Based Case-Control Study of Breast Cancer Patients Treated with Cyclophosphamide Epirubicin and 5-fluorouracil...

  20. Occupational exposure to the sun and risk of skin and lip cancer among male wage earners in Denmark: a population-based case-control study

    DEFF Research Database (Denmark)

    Kenborg, Line; Jørgensen, Ane Dahl; Budtz-Jørgensen, Esben;

    2010-01-01

    We examined the association between outdoor work and the risks of non-melanoma skin cancer, cutaneous malignant melanoma, and lip cancer in a population-based case-control study.......We examined the association between outdoor work and the risks of non-melanoma skin cancer, cutaneous malignant melanoma, and lip cancer in a population-based case-control study....

  1. Structural Path Analysis of Fossil Fuel Based CO2 Emissions: A Case Study for China

    Science.gov (United States)

    Yang, Zhiyong; Dong, Wenjie; Xiu, Jinfeng; Dai, Rufeng; Chou, Jieming

    2015-01-01

    Environmentally extended input-output analysis (EEIOA) has long been used to quantify global and regional environmental impacts and to clarify emission transfers. Structural path analysis (SPA), a technique based on EEIOA, is especially useful for measuring significant flows in this environmental-economic system. This paper constructs an imports-adjusted single-region input-output (SRIO) model considering only domestic final use elements, and it uses the SPA technique to highlight crucial routes along the production chain in both final use and sectoral perspectives. The results indicate that future mitigation policies on household consumption should change direct energy use structures in rural areas, cut unreasonable demand for power and chemical products, and focus on urban areas due to their consistently higher magnitudes than rural areas in the structural routes. Impacts originating from government spending should be tackled by managing onsite energy use in 3 major service sectors and promoting cleaner fuels and energy-saving techniques in the transport sector. Policies on investment should concentrate on sectoral interrelationships along the production chain by setting up standards to regulate upstream industries, especially for the services, construction and equipment manufacturing sectors, which have high demand pulling effects. Apart from the similar methods above, mitigating policies in exports should also consider improving embodied technology and quality in manufactured products to achieve sustainable development. Additionally, detailed sectoral results in the coal extraction industry highlight the onsite energy use management in large domestic companies, emphasize energy structure rearrangement, and indicate resources and energy safety issues. Conclusions based on the construction and public administration sectors reveal that future mitigation in secondary and tertiary industries should be combined with upstream emission intensive industries in a

  2. Strategic Planning Model Formulation Based on Balanced Score Card: A Case Study

    Directory of Open Access Journals (Sweden)

    Elaheh Enteshari Najaf Abadi

    2012-07-01

    Full Text Available At the present age, strategic planning is considered as an important and vital matter for organizations and formulating and implementing strategic plans and accurate parameters may result in organizations long-term superiority in competitive field. But, regarding that competitive factors of all organizations are not the same, formulating the strategy with a similar trend is unlikely to be effective and the prerequisite for success of any organization is to focus and pay attention to its own capacities and unique competitive advantages and to formulate strategies based on those capacities along with focusing on the weakness and threats points. This article presents a model integrated of the strategic planning process and balanced score card and considering four dimensions of the Balanced Score Card (BSC, it accomplishes the process of strategic planning in the fields of financial, customer, internal processes and growth and learning separately and then determines the position of an organization in each dimension. Therefore, the strength and weakness points of the organization are identified and the type of strategies needed for any dimension determined separately. With the aid of this model, top managers are able to determine the organization expects and goals of different sectors clearly and in line with the vision and strategy of organization and deliver to the managers and authorities of different sectors. The results of this model are the analysis of factors influencing on the strategy formulation, extraction of key dimensions, provision of the SWOT matrix for four-folds dimensions of BSC and the identification of organization situation in each dimension such that through basing it on, integrated strategies and operational plans will be formulated for the organization. In this survey, Isfahan Company of tile industry has been studied as a sample and the results of the model implementation for this company described in the text.

  3. Structural Path Analysis of Fossil Fuel Based CO2 Emissions: A Case Study for China.

    Directory of Open Access Journals (Sweden)

    Zhiyong Yang

    Full Text Available Environmentally extended input-output analysis (EEIOA has long been used to quantify global and regional environmental impacts and to clarify emission transfers. Structural path analysis (SPA, a technique based on EEIOA, is especially useful for measuring significant flows in this environmental-economic system. This paper constructs an imports-adjusted single-region input-output (SRIO model considering only domestic final use elements, and it uses the SPA technique to highlight crucial routes along the production chain in both final use and sectoral perspectives. The results indicate that future mitigation policies on household consumption should change direct energy use structures in rural areas, cut unreasonable demand for power and chemical products, and focus on urban areas due to their consistently higher magnitudes than rural areas in the structural routes. Impacts originating from government spending should be tackled by managing onsite energy use in 3 major service sectors and promoting cleaner fuels and energy-saving techniques in the transport sector. Policies on investment should concentrate on sectoral interrelationships along the production chain by setting up standards to regulate upstream industries, especially for the services, construction and equipment manufacturing sectors, which have high demand pulling effects. Apart from the similar methods above, mitigating policies in exports should also consider improving embodied technology and quality in manufactured products to achieve sustainable development. Additionally, detailed sectoral results in the coal extraction industry highlight the onsite energy use management in large domestic companies, emphasize energy structure rearrangement, and indicate resources and energy safety issues. Conclusions based on the construction and public administration sectors reveal that future mitigation in secondary and tertiary industries should be combined with upstream emission intensive

  4. ASME stress linearization and classification - a discussion based on a case study

    International Nuclear Information System (INIS)

    The ASME code, specially in its Nuclear Division (Subsection NB - Class I Components), gives some recommendations to the structural analyst on how to perform the verifications required to prove the design as good as the by-analysis prevented failures modes. Each of these failure modes has specific stress limits which are established based on simple but conservative hypothesis like the material perfectly plastic behavior and the shell theory with its typical membrane and bending stresses with linear distribution along the thickness. Other detail to keep in mind is the code distinction between primary and secondary stresses (respectively, stress that came due to equilibrium and due to displacement compatibility). In general, the numerical models used in the analyses are developed with plane or 3D solid elements and due this fact no direct comparison with the code limits can be done and, besides that, the programs do not distinguish between primary and secondary stresses. Mostly, the later are produced due to the temperature variation but they also appear near discontinuities. Sometimes, this classification is not so clear or direct. To perform the required ASME Code verifications the analyst should obtain the membrane and bending stresses from the plane or 3-D model which is called stress linearization and, also, should classify them as primary and secondary. (The excess between the maximum stress at a point and the sum of these linearized values is called peak stress and is included in the fatigue verification.) This task, most of the time is not a simple one due to the nature of the involved load and/or the complex geometry under analysis. In fact, there are several studies discussing on how to perform these stress classification and linearization. The present paper shows a discussion on how to perform these verifications based on a generic geometry found in many plants, from petrochemical to nuclear, which emphasizes some of theses issues. (author)

  5. Assessment of Urban Plantation Climate-Regulating Function based on Remote Sensing Data (Case Study Moscow)

    Science.gov (United States)

    Sandlerskiy, Robert

    2010-05-01

    A variety of active surfaces in combination with various building levels forms a specific urban mode of atmospheric turbulence. The spatial combination of green plantings, asphalt and building defines a temperature and wind mode, and creates various air circulation systems. Influence of spatial structure and buildings height on a wind mode of urban territories is full enough studied in town-planning. Assessment of the input to formation of urban climate of surfaces with various heat capacity and, vegetation is not developed. This assessment can be based on the multispectral remote sensing data which contain information on energetic surface condition. Multispectral data development make possible a calculation of the basic energetic characteristics of surfaces: input and absorption of solar energy, energy consumption on evapotranspiration, thermal scattering and accumulation, a heat flux and temperature of surface. This technique gives a possibility to estimate a thermal mode of surface at various spatial scales. In world practice urban landscapes condition estimation based on remote data (Urban Remote Sensing) is underdeveloped, and focused, mainly, on temperature and heat flux estimation. For energetic characteristics estimation for Moscow territory we use Landsat 5 TM and 7 ETM + remote sensing data for three terms in the vegetational season: May (26/05/2003), July (21/07/2003), August (17/08/2007), with the spatial resolution 30х30 m for 6 channels in a short-wave range and 60х60 m - for the thermal channel. Mean values of calculated temperatures have been compared to daily temperatures on a municipal meteorological station. The calculated energetic characteristics have been analyzed to estimate independent factors which determine their spatial variation. Basing on the estimated factors we classify surface, and allocate surface types with a various temperature and energetic mode. Next we calculate mean values of energetic characteristics to each type. Type

  6. Understanding the context of balanced scorecard implementation: a hospital-based case study in pakistan

    Directory of Open Access Journals (Sweden)

    Ajmal Agha

    2011-03-01

    Full Text Available Abstract Background As a response to a changing operating environment, healthcare administrators are implementing modern management tools in their organizations. The balanced scorecard (BSC is considered a viable tool in high-income countries to improve hospital performance. The BSC has not been applied to hospital settings in low-income countries nor has the context for implementation been examined. This study explored contextual perspectives in relation to BSC implementation in a Pakistani hospital. Methods Four clinical units of this hospital were involved in the BSC implementation based on their willingness to participate. Implementation included sensitization of units towards the BSC, developing specialty specific BSCs and reporting of performance based on the BSC during administrative meetings. Pettigrew and Whipp's context (why, process (how and content (what framework of strategic change was used to guide data collection and analysis. Data collection methods included quantitative tools (a validated culture assessment questionnaire and qualitative approaches including key informant interviews and participant observation. Results Method triangulation provided common and contrasting results between the four units. A participatory culture, supportive leadership, financial and non-financial incentives, the presentation of clear direction by integrating support for the BSC in policies, resources, and routine activities emerged as desirable attributes for BSC implementation. The two units that lagged behind were more involved in direct inpatient care and carried a considerable clinical workload. Role clarification and consensus about the purpose and benefits of the BSC were noted as key strategies for overcoming implementation challenges in two clinical units that were relatively ahead in BSC implementation. It was noted that, rather than seeking to replace existing information systems, initiatives such as the BSC could be readily adopted if

  7. Risk Factors for Pancreatic Neuroendocrine Tumors (PNETs): A Clinic-Based Case-Control study

    Science.gov (United States)

    Halfdanarson, Thorvardur R.; Bamlet, William R.; McWilliams, Robert R; Hobday, Timothy J.; Burch, Patrick A.; Rabe, Kari G.; Petersen, Gloria M.

    2014-01-01

    Objectives Pancreatic neuroendocrine tumors (PNETs) are uncommon, and little is known about their risk factors and association with other cancers. We evaluated whether risk factors known to be associated with pancreatic adenocarcinoma are also associated with PNETs: smoking, alcohol use, family history of PNET and other cancers, and personal history of diabetes as potential risk factors. Methods Patients with PNETs seen at Mayo Clinic Rochester between 2000 and 2011 were compared to controls seen for a general medical evaluation. Patients and controls completed the same questionnaires. After excluding insulinoma and high-grade PNETs, 355 cases were evaluated, and 309 were matched to 602 controls (2:1) on age, sex, and region of residence. Results Personal smoking history was not associated with PNETs. Alcohol use was less common among cases (54% vs. 67%, p<0.001). Cases were more likely to report a family member with sarcoma (p=0.02), PNET (p=0.02), gall bladder cancer (p=0.02), ovarian cancer (p=0.04) and gastric cancer (p=0.01). There was no association with other cancers in family members. Diabetes was more commonly reported by cases than controls (19% vs. 11%, p<0.001). Conclusions With the exception of diabetes, risk factors that are associated with pancreatic adenocarcinoma are not risk factors for PNETs. PMID:25291526

  8. Juicing the Juice: A Laboratory-Based Case Study for an Instrumental Analytical Chemistry Course

    Science.gov (United States)

    Schaber, Peter M.; Dinan, Frank J.; St. Phillips, Michael; Larson, Renee; Pines, Harvey A.; Larkin, Judith E.

    2011-01-01

    A young, inexperienced Food and Drug Administration (FDA) chemist is asked to distinguish between authentic fresh orange juice and suspected reconstituted orange juice falsely labeled as fresh. In an advanced instrumental analytical chemistry application of this case, inductively coupled plasma (ICP) spectroscopy is used to distinguish between the…

  9. Getting water right: A case study in water yield modelling based on precipitation data.

    Science.gov (United States)

    Pessacg, Natalia; Flaherty, Silvia; Brandizi, Laura; Solman, Silvina; Pascual, Miguel

    2015-12-15

    Water yield is a key ecosystem service in river basins and especially in dry regions around the World. In this study we carry out a modelling analysis of water yields in the Chubut River basin, located in one of the driest districts of Patagonia, Argentina. We focus on the uncertainty around precipitation data, a driver of paramount importance for water yield. The objectives of this study are to: i) explore the spatial and numeric differences among six widely used global precipitation datasets for this region, ii) test them against data from independent ground stations, and iii) explore the effects of precipitation data uncertainty on simulations of water yield. The simulations were performed using the ecosystem services model InVEST (Integrated Valuation of Ecosystem Services and Tradeoffs) with each of the six different precipitation datasets as input. Our results show marked differences among datasets for the Chubut watershed region, both in the magnitude of precipitations and their spatial arrangement. Five of the precipitation databases overestimate the precipitation over the basin by 50% or more, particularly over the more humid western range. Meanwhile, the remaining dataset (Tropical Rainfall Measuring Mission - TRMM), based on satellite measurements, adjusts well to the observed rainfall in different stations throughout the watershed and provides a better representation of the precipitation gradient characteristic of the rain shadow of the Andes. The observed differences among datasets in the representation of the rainfall gradient translate into large differences in water yield simulations. Errors in precipitation of +30% (-30%) amplify to water yield errors ranging from 50 to 150% (-45 to -60%) in some sub-basins. These results highlight the importance of assessing uncertainties in main input data when quantifying and mapping ecosystem services with biophysical models and cautions about the undisputed use of global environmental datasets. PMID:26282756

  10. Physiologically Based Absorption Modeling to Impact Biopharmaceutics and Formulation Strategies in Drug Development-Industry Case Studies.

    Science.gov (United States)

    Kesisoglou, Filippos; Chung, John; van Asperen, Judith; Heimbach, Tycho

    2016-09-01

    In recent years, there has been a significant increase in use of physiologically based pharmacokinetic models in drug development and regulatory applications. Although most of the published examples have focused on aspects such as first-in-human (FIH) dose predictions or drug-drug interactions, several publications have highlighted the application of these models in the biopharmaceutics field and their use to inform formulation development. In this report, we present 5 case studies of use of such models in this biopharmaceutics/formulation space across different pharmaceutical companies. The case studies cover different aspects of biopharmaceutics or formulation questions including (1) prediction of absorption prior to FIH studies; (2) optimization of formulation and dissolution method post-FIH data; (3) early exploration of a modified-release formulation; (4) addressing bridging questions for late-stage formulation changes; and (5) prediction of pharmacokinetics in the fed state for a Biopharmaceutics Classification System class I drug with fasted state data. The discussion of the case studies focuses on how such models can facilitate decisions and biopharmaceutic understanding of drug candidates and the opportunities for increased use and acceptance of such models in drug development and regulatory interactions. PMID:26886317

  11. Mobile Phone Based RIMS for Traffic Control a Case Study of Tanzania

    Directory of Open Access Journals (Sweden)

    Angela-Aida Karugila Runyoro

    2015-04-01

    Full Text Available Vehicles saturation in transportation infrastructure causes traffic congestion, accidents, transportation delays and environment pollution. This problem can be resolved with proper management of traffic flow. Existing traffic management systems are challenged on capturing and processing real-time road data from wide area road networks. The main purpose of this study is to address the gap by implementing a mobile phone based Road Information Management System. The proposed system integrates three modules for data collection, storage and information dissemination. The modules works together to enable real-time traffic control. Disseminated information from the system, enables road users to adjust their travelling habit, also it allows the traffic lights to control the traffic in relation to the real-time situation occurring on the road. In this paper the system implementation and testing was performed. The results indicated that there is a possibility to track traffic data using Global Positioning System enabled mobile phones, and after processing the collected data, real-time traffic status was displayed on web interface. This enabled road users to know in advance the situation occurring on the roads and hence make proper travelling decision. Further research should consider adjusting the traffic lights control system to understand the disseminated real-time traffic information.

  12. Results based management in Albanian local governments. Case study municipality of Korca

    Directory of Open Access Journals (Sweden)

    Eva Dhimitri

    2012-12-01

    Full Text Available Public Management has been a constant concern for all politicians and public administrators at all levels of governance in Albania. Increase of public demand for higher accountability, efficiency in the administration of public goods and services is now challenging the traditional means of governance by so aiming tangible results in the public management. Results Based Management (RBM is a new approach in the public management, a practice already developed in the western countries. RBM is defined as an approach that integrates in one whole instrument the strategies, human resources, processes and their evaluation, with the aim of improving decision-making, transparency, and accountability of public institutions. This study makes an effort to approximate and clarify as simply as possible such a management scheme which remains a relatively new approach for Albania and especially for local governance stakeholders. RBM is not only a planning-monitoring -evaluation tool but also a model that can facilitate the activity and development of Local Government Units in order for them to improve their “product/services”. From empirical data deriving from this prior assessment it results that municipality of Korca in Albania have the willingness and the institutional and technical capacities, though very fragmented and not integrated in one whole clear model, to embrace the RBM as a new approach in their institution’s management.

  13. A case study of fluid flow in fractured rock mass based on 2-D DFN modeling

    Science.gov (United States)

    Han, Jisu; Noh, Young-Hwan; Um, Jeong-Gi; Choi, Yosoon

    2014-05-01

    A two dimensional steady-state fluid flow through fractured rock mass of an abandoned copper mine in Korea is addressed based on discrete fracture network modeling. An injection well and three observation wells were installed at the field site to monitor the variations of total heads induced by injection of fresh water. A series of packer tests were performed to estimate the rock mass permeability. First, the two dimensional stochastic fracture network model was built and validated for a granitic rock mass using the geometrical and statistical data obtained from surface exposures and borehole logs. This validated fracture network model was combined with the fracture data observed on boreholes to generate a stochastic-deterministic fracture network system. Estimated apertures for each of the fracture sets using permeability data obtained from borehole packer tests were discussed next. Finally, a systematic procedure for fluid flow modeling in fractured rock mass in two dimensional domain was presented to estimate the conductance, flow quantity and nodal head in 2-D conceptual linear pipe channel network. The results obtained in this study clearly show that fracture geometry parameters (orientation, density and size) play an important role in the hydraulic behavior of fractured rock masses.

  14. [Regional ecosecurity pattern in urban area based on land use analysis: a case study in Lanzhou].

    Science.gov (United States)

    Fang, Shubo; Xiao, Dunin; An, Shuqing

    2005-12-01

    Mid-scale regional ecosecurity, which takes practical ecosecurity issues as its priority, should be viewed as the core of the multi-scale concept of ecosecurity. For urban area, a special region taking ecological infrastructure as its core mission, the construction of regional ecosecurity pattern may provide a good chance to realize its sustainable development. Based on land use analysis, a qualitative and quantitative research on the landscape pattern, ecovalue evaluation, and driving force analysis of social economy could provide an effective approach to construct the ecosecurity pattern in urban area. This study showed that in Lanzhou, the ecosecurity pattern consisted of three parts, i.e., eco-safeguarding system, eco-buffering system and eco-percolating system, among which, eco-buffering system was the decisive part determining ecosecurity pattern construction. The quantitative analysis of urban spatial expansion pattern was taken as the decisive function to determine the security level of the ecosecurity pattern, which was divided into low, middle and high levels. PMID:16515173

  15. GIS based geothermal potential assessment: A case study from Western Anatolia, Turkey

    International Nuclear Information System (INIS)

    Potential geothermal areas are identified through investigation of spatial relations between geothermal occurrences and their surrounding geological phenomena in western Anatolia, Turkey. The identification is based on only publicly available data. It is expected that the study will guide further preliminary investigations performed for large areas having limited information. Magnetic anomaly, Bouger gravity anomaly, earthquake epicenter and lineament datasets are used for the analysis. The first is used without any modification whereas the rest are utilized to extract three evidence maps; distance to major grabens, Gutenberg-Richter b-value and distance to lineaments, respectively. Predictor maps are produced from these evidence maps as well as from the unprocessed magnetic anomaly map by applying two different binarization procedures. From each binarization procedure a favorability map is produced separately using Index Overlay (IO) and Weights of Evidence (WofE) methods. The findings reveal that weighting predictor maps according to spatial association between evidence maps and training points lead to more accurate prediction in both WofE and IO methods. The potential areas in the final maps are Aydin, Denizli, Manisa, Balikesir and Kutahya of which first two have been explored and exploited, and thus found to be favorable, while the rest are nearly unexplored.

  16. Analysis of Land-Use Emergy Indicators Based on Urban Metabolism: A Case Study for Beijing

    Directory of Open Access Journals (Sweden)

    Qing Huang

    2015-06-01

    Full Text Available The correlation of urban metabolism and changes in land use is an important issue in urban ecology, but recent research lacks consideration of the mechanisms and interactions between them. In this research, we did an emergy analysis of the flows of materials, energy, and capital within the socioeconomic system of Beijing. We calculated emergy-based evaluation indices of urban metabolism and land use change, to analyze the relationship between urban metabolism and land use by correlation analysis and regression analysis. Results indicate that the socio-economic activities on built-up land depend on local, non-renewable resource exploitation and external resource inputs. The emergy utilization efficiency of farmland has consistently decreased, but there remains significant utilization potential there. Urban development in Beijing relies on production activities on built-up land, which is subjected to great environmental pressure during extraction of material resources. To keep the economy developing effectively, we suggest that Beijing should commit to development of a circular economy, and change the land-use concept to “Smart Growth”. In this paper, we efficaciously solve the problem of conflicting measurement units, and avoid the disadvantages of subjective assignment. Consequently, this work provides not only a more scientific way to study land problems, but also provides a reliable reference for ecological construction and economic development in Beijing.

  17. Biological mode of action of a nitrophenolates-based biostimulant: Case study

    Directory of Open Access Journals (Sweden)

    Arkadiusz ePrzybysz

    2014-12-01

    Full Text Available The challenges facing modern plant production involve (i responding to the demand for food and resources of plant origin from the world’s rapidly growing population, (ii coping with the negative impact of stressful conditions mainly due to anthropopressure, and (iii meeting consumers’ new requirements and preferences for food that is high in nutritive value, natural, and free from harmful chemical additives.Despite employing the most modern plant cultivation technologies and the progress that has been made in breeding programs, the genetically-determined crop potential is still far from being fully exploited. Consequently yield and quality are often reduced, making production less, both profitable and attractive. There is an increasing desire to reduce the chemical input in agriculture and there has been a change towards integrated plant management and sustainable, environmentally-friendly systems. Biostimulants are a category of relatively new products of diverse formulations that positively affect a plant’s vital processes and whose impact is usually more evident under stressful conditions. In this paper, information is provided on the mode of action of a nitrophenolates-based biostimulant, Atonik, in model species and economically important crops grown under both field and controlled conditions in a growth chamber. The effects of Atonik on plant morphology, physiology, biochemistry (crops and model plant and yield and yield parameters (crops is demonstrated. Effects of other biostimulants on studied in this work processes/parameters are also presented in discussion.

  18. Risk factors for acute Toxoplasma gondii diseases in Taiwan: a population-based case-control study.

    Directory of Open Access Journals (Sweden)

    Ting-Yi Chiang

    Full Text Available Although human toxoplasmosis is a notifiable disease in Taiwan since 2007, little is known about its risk factors. This study aimed to investigate the risk factors for acute Toxoplasma gondii diseases in Taiwan. We conducted a nationwide population-based case-control study. Cases of acute human toxoplasmosis notified to the Taiwan Centers for Diseases Control (Taipei, Taiwan during 2008-2013 were compared with controls that were randomly selected from healthy T. gondii-seronegative blood donors who participated in a nationwide T. gondii seroepidemiologic study during 2009-2010. Cases and controls were matched according to age, gender and residency at an 1:8 ratio. Structured questionnaires were used to gather information regarding risk factors. A total of 30 laboratory-confirmed acute T. gondii disease cases and 224 controls were enrolled. The most common clinical manifestation of the cases was flu-like symptoms (n = 20, followed by central nervous system disease (n = 4, ocular diseases (n = 3, abortion (n = 2, and congenital infection (n = 1. Multivariate conditional logistic regression showed that raw clam consumption (adjusted odds ratio [OR] = 3.7; 95% confidence interval [CI] = 1.4-9.9 and having a cat in the household (adjusted OR = 2.9; 95% CI = 1.1-7.9 were two independent risk factors for acute T. gondii disease. We conclude that raw shellfish consumption and domestic cat exposure were risk factors for acquiring acute T. gondii diseases in Taiwan. This finding may guide future research and control policies.

  19. Occupational risk factors for small bowel carcinoid tumor: a European population-based case-control study.

    Science.gov (United States)

    Kaerlev, Linda; Teglbjaerg, Peter Stubbe; Sabroe, Svend; Kolstad, Henrik A; Ahrens, Wolfgang; Eriksson, Mikael; Guénel, Pascal; Hardell, Lennart; Cyr, Diane; Ballard, Terri; Zambon, Paola; Morales Suárez-Varela, María M; Stang, Andreas; Olsen, Jorn

    2002-06-01

    Small bowel carcinoid tumor (SBC) is a rare disease of unknown etiology but with an age-, sex-, and place-specific occurrence that may indicate an occupational origin. A European multicenter population-based case-control study was conducted from 1995 through 1997. Incident SBC cases between 35 and 69 years of age (n = 101) were identified, together with 3335 controls sampled from the catchment area of the cases. Histological review performed by a reference pathologist left 99 cases for study; 84 cases and 2070 population controls were interviewed. The industries most closely associated (a twofold or more odds ratio [OR]) with SBC, taking into account a 10-year time lag after exposure were, among women, employment in wholesale industry of food and beverages (OR, 8.2; 95% confidence interval [CI], 1.9 to 34.9]) and among men, manufacture of motor vehicle bodies (OR, 5.2; 95% CI, 1.2 to 22.4), footwear (OR, 3.9; 95% CI, 0.9 to 16.1), and metal structures (OR, 3.3; 95% CI, 1.0 to 10.4). The identified high-risk occupations with an OR above 2 were shoemakers, structural metal preparers, construction painters and other construction workers, bookkeepers, machine fitters, and welders (men). The OR for regular occupational use of organic solvents for at least half a year was 2.0 (95% CI, 1.0 to 4.2). Exposure to rust-preventive paint containing lead was suggested as another potential occupational exposure (OR, 9.1; 95% CI, 0.8 to 107). This explorative study suggests an association between certain occupational exposures and SBC, but some of these associations could be attributable to chance. All findings should be regarded as tentative. PMID:12085477

  20. Life cycle inventory for palm based plywood: A gate-to-gate case study

    Science.gov (United States)

    Ahmad, Shamim; Sahid, Ismail; Subramaniam, Vijaya; Muhamad, Halimah; Mokhtar, Anis

    2013-11-01

    The oil palm industry heavily relies on the world market. It is essential to ensure that the oil palm industry is ready to meet the demands and expectation of these overseas customers on the environmental performance of the oil palm industry. Malaysia produces 13.9 million tons of oil palm biomass including oil palm trunk (OPT), frond and empty fruits bunches (EFB) annually. OPT felled in some oil palm plantations during replanting is transported to various industries and one such industry is the plywood factories. In order to gauge the environmental performance of the use of OPT as plywood a Life Cycle Assessment (LCA) study was conducted for palm based plywood. LCA is an important tool to assess the environmental performance of a product or process. Life cycle inventory (LCI) is the heart of a LCA study. This LCI study has a gate-to-gate system boundary and the functional unit is 1 m3 palm plywood produced and covers three types of plywood; Moisture Resistance Plywood (MR), Weather Boiling Proof Plywood Grade 1 (WBP Grade 1) at Factory D and Weather Boiling Proof Plywood Grade 2 (WBP Grade 2) at Factory E. Both factories use two different types of drying processes; conventional drying at Factory D and kiln drying at Factory E. This inventory data was collected from two factories (D and E) representing 40% of Malaysia palm plywood industry. The inputs are mainly the raw materials which are the oil palm trunks and tropical wood veneers and the energy from diesel and electricity from grid which is mainly used for the drying process. The other inputs include water, urea formaldehyde, phenol formaldehyde, flour and melamine powder. The outputs are the biomass waste which consists of oil palm trunk off-cut and emission from boiler. Generally, all types of plywood production use almost same materials and processing methods in different quantities. Due to the different process efficiency, Factory D uses less input of raw materials and energy compared to Factory E.

  1. Using FLAME Toolkit for Agent-Based Simulation: Case Study Sugarscape Model

    OpenAIRE

    Kiran, Mariam

    2014-01-01

    Social scientists have used agent-based models to understand how individuals interact and behave in various political, ecological and economic scenarios. Agent-based models are ideal for understanding such models involving interacting individuals producing emergent phenomenon. Sugarscape is one of the most famous examples of a social agent-based model which has been used to show how societies grow in the real world. This paper builds on the Sugarscape model, using the Flexible Large scale Age...

  2. Developing a comprehensive knowledge management approach for ICT-based professional services companies: case study

    OpenAIRE

    Janus-Hiekkaranta, Agnieszka

    2009-01-01

    OBJECTIVES OF THE THESIS The objective of this thesis is to find out how a comprehensive and coherent knowledge management (KM) system should be developed in an information technology-based professional services firm. The objective was based on the assumption that KM development schemes in knowledge-intensifive companies have to comprise all company strategic, structural and operational parts. THEORY, RESEARCH METHODS AND PROCESS The main theories the thesis is based on: the knowl...

  3. CHARACTERISTICS OF VALUE BASED FOOD CHAIN IN ORGANIC SECTOR (case studies from Slovenia)

    OpenAIRE

    Prišenk, Jernej; Borec, Andreja

    2015-01-01

    In the literature the value based food chains express two main characteristics: business relationships among strategic partners interacting in the supply chain are based on a written set of values and food products are differentiated from similar food products based on product attributes such as food quality, safety, and/or functionality along with environmental and social attributes (Stevenson, 2009). To verify the first part of the definition the analysis of two organic food chains where ca...

  4. Creating Sustainable Competitive Advantage using Resource Based Review: Case study of Citigroup

    OpenAIRE

    Pang, Shay

    2007-01-01

    This report shall focus on the creation of sustainable competitive advantage in Citigroup based on the Resource Based View approach. The main motivation behind this research is to understand what constitutes to Citigroup SCA from its humble beginnings as a small local bank to the world largest bank today. Through this research, I hope to unravel some of these possible sources of SCA in Citigroup. Literature based on the RBV concept was used to propose a framework from which we analyze Cit...

  5. Statins and the risk of acute pancreatitis: A population-based case-control study

    DEFF Research Database (Denmark)

    Thisted, Henriette; Jacobsen, Jacob; Munk, Estrid Muff;

    2006-01-01

    BACKGROUND: Case reports have suggested that statins may cause acute pancreatitis. AIM: To examine if statins are associated with risk of acute pancreatitis. METHODS: We identified 2576 first-time admitted cases of acute pancreatitis from hospital discharge registers in three Danish counties, and...... 25 817 age- and gender-matched controls from the general population. Prescriptions for statins prior to admission with acute pancreatitis or index date among controls were retrieved from prescription databases. We used conditional logistic regression analysis to estimate odds ratios for acute...... pancreatitis among ever (ever before), current (0-90 days before), new (first prescription in 0-90 days before) and former (>90 days, but not 0-90 days before) users of statins. RESULTS: Adjusted odds ratios for acute pancreatitis among ever, current, new and former users of statins were 1.44 (95% confidence...

  6. MINI REVIEW ARTICLE:Immunohistochemistry of Epithelioid Soft Tissue Sarcomas, Literature Review Based on Case Studies

    Directory of Open Access Journals (Sweden)

    Megha Joshi

    2012-07-01

    Full Text Available Neoplasms with epithelioid histology may be diagnostically challenging. Immunohisto chemistry (IHC can aid in confirming thedifferential diagnosis of mesotheliomas, melanomas, lymphomas, and soft tissue sarcomas, all tumors that can present with an epithelioid histology. Immunohistochemistry can also assist in confirming the type of sarcomas. Using cases diagnosed in acommunity hospital setting over a ten year period, the use of IHC in sarcomas will be illustrated.

  7. Gender Based Discrimination in Marriage and Family Life : A Case Study of Pakistan

    OpenAIRE

    2010-01-01

    Traditional values and conservative religious interpretations are considered to be a great challenge to the international human rights regime. This is true especially in the case of Pakistan where women’s human rights are being immolated on traditional and religious values. Their status is reduced to a puppet to get desired performance and obedience in the family life. This paper makes an effort to measure the severeness of discriminatory behavior of men toward women in marriage and family li...

  8. Human resource development for a community-based health extension program: a case study from Ethiopia

    OpenAIRE

    Teklehaimanot, Hailay D; Teklehaimanot, Awash

    2013-01-01

    Introduction Ethiopia is one of the sub-Saharan countries most affected by high disease burden, aggravated by a shortage and imbalance of human resources, geographical distance, and socioeconomic factors. In 2004, the government introduced the Health Extension Program (HEP), a primary care delivery strategy, to address the challenges and achieve the World Health Organization Millennium Development Goals (MDGs) within a context of limited resources. Case description The health system was refor...

  9. Strategic approaches to simulation-based education: A case study from Australia

    OpenAIRE

    Debra Nestel; Marcus O Watson; Margaret L Bearman; Tracy Morrison; Pritchard, Shane A; Pamela B Andreatta

    2013-01-01

    This paper addresses some of the challenges met when developing widely distributed, broad spectrum, simulation-based education (SBE) for health professionals, such as resource duplication, inconsistent facilities utilization, discipline-specific silos, and the intersection of academic institutions and health services sectors. We examine three primary contributors to successful simulation-based practices - strategic planning, program development, and professional networks. Further, we provide ...

  10. Increasing Teachers' Use of Evidence-Based Classroom Management Strategies through Consultation: Overview and Case Studies

    Science.gov (United States)

    MacSuga, Ashley S.; Simonsen, Brandi

    2011-01-01

    Many classroom teachers are faced with challenging student behaviors that impact their ability to facilitate learning in productive, safe environments. At the same time, high-stakes testing, increased emphasis on evidence-based instruction, data-based decision making, and response-to-intervention models have put heavy demands on teacher time and…

  11. Case Study of a Project-Based Learning Course in Civil Engineering Design

    Science.gov (United States)

    Gavin, K.

    2011-01-01

    This paper describes the use of project-based learning to teach design skills to civil engineering students at University College Dublin (UCD). The paper first considers the development of problem-based leaning (PBL) as a tool in higher education. The general issues to be considered in the design of the curriculum for a PBL module are reviewed.…

  12. A case study of GIS-based geotechnical database in urban environment (Oviedo, NW Spain)

    Science.gov (United States)

    Pando, Luis; María Díaz-Díaz, Luis; Arias, Daniel; Flor-Blanco, Germán

    2014-05-01

    This contribution describes the development and usefulness of a GIS-type geotechnical database designed for Oviedo, a mid-size urban core in northwestern Spain. This city is located on a Mesozoic-Palaeogene basin with a gentle synclinal structure, placed on a basement of strongly folded Devonian and Carboniferous formations. The Cretaceous consists of alternating carbonate and siliciclastic units, while the unconformable Palaeogene series, of fluvial-lacustrine origin, are chiefly composed of marls and clays with intercalated calcareous and gypsiferous layers. The relational database generated contains a wide range of unpublished subsurface data, mostly provided over the past six decades by geotechnical reports and fieldwork. The information was specifically collected and 3D georeferenced (X, Y, Z coordinates) for this research in order to ensure its spatial consistency and conservation. Currently the database includes 2,200 site investigations, a thousand on-site tests, and the results from 4,000 laboratory tests carried out on 1,600 samples of rocks, soils and groundwater. Moreover the database is supplemented with approximately 250 cartographic files and aerial images, all georeferenced. Through different spatial analysis methods, the geodata stored were processed to study the distribution and thickness of the surficial deposits (man-made fills, alluvial sediments and residual soils), and also to address the identification of unknown faults crossing below the urban area. Moreover, the main properties of all the rocks and soils in the study area were assessed using geotechnical parameters compiled from laboratory and field testing. The results obtained, examined by descriptive statistics, are useful as bibliographical reference for further research. This made possible to review the lithostratigraphic division of the Palaeogene; as a result six sections were defined instead of the three gathered in previous investigations. Regarding urban hydrogeology the

  13. Chronic obstructive pulmonary disease and altered risk of lung cancer in a population-based case-control study.

    Directory of Open Access Journals (Sweden)

    Jill Koshiol

    Full Text Available BACKGROUND: Chronic obstructive pulmonary disease (COPD has been consistently associated with increased risk of lung cancer. However, previous studies have had limited ability to determine whether the association is due to smoking. METHODOLOGY/PRINCIPAL FINDINGS: The Environment And Genetics in Lung cancer Etiology (EAGLE population-based case-control study recruited 2100 cases and 2120 controls, of whom 1934 cases and 2108 controls reported about diagnosis of chronic bronchitis, emphysema, COPD (chronic bronchitis and/or emphysema, or asthma more than 1 year before enrollment. We estimated odds ratios (OR and 95% confidence intervals (CI using logistic regression. After adjustment for smoking, other previous lung diseases, and study design variables, lung cancer risk was elevated among individuals with a history of chronic bronchitis (OR = 2.0, 95% CI = 1.5-2.5, emphysema (OR = 1.9, 95% CI = 1.4-2.8, or COPD (OR = 2.5, 95% CI = 2.0-3.1. Among current smokers, association between chronic bronchitis and lung cancer was strongest among lighter smokers. Asthma was associated with a decreased risk of lung cancer in males (OR = 0.48, 95% CI = 0.30-0.78. CONCLUSIONS/SIGNIFICANCE: These results suggest that the associations of personal history of chronic bronchitis, emphysema, and COPD with increased risk of lung cancer are not entirely due to smoking. Inflammatory processes may both contribute to COPD and be important for lung carcinogenesis.

  14. The Evolution of Network-based Business Models Illustrated Through the Case Study of an Entrepreneurship Project

    Directory of Open Access Journals (Sweden)

    Morten Lund

    2014-08-01

    Full Text Available Purpose: Existing frameworks for understanding and analyzing the value configuration and structuring of partnerships in relation such network-based business models are found to be inferior. The purpose of this paper is therefore to broaden our understanding of how business models may change over time and how the role of strategic partners may differ over time too. Design/methodology/approach: A longitudinal case study spanning over years and mobilising multiple qualitative methods such as interviews, observation and participative observation forms the basis of the data collection. Findings: This paper illustrates how a network-based business model arises and evolves and how the forces of a network structure impact the development of its partner relationships. The contribution of this article is to understanding how partners positioned around a business model can be organized into a network-based business model that generates additional value for the core business model and for both the partners and the customers. Research limitations/implications: The results should be taken with caution as they are based on the case study of a single network-based business model. Practical implications: Managers can gain insight into barriers and enablers relating to different types of loose organisations and how to best manage such relationships and interactions Originality/value: This study adds value to the existing literature by reflecting the dynamics created in the interactions between a business model’s strategic partners and how a how a business model can evolve in a series of distinct phases

  15. Defining Boundaries for Ecosystem-Based Management: A Multispecies Case Study of Marine Connectivity across the Hawaiian Archipelago

    Directory of Open Access Journals (Sweden)

    Robert J. Toonen

    2011-01-01

    Full Text Available Determining the geographic scale at which to apply ecosystem-based management (EBM has proven to be an obstacle for many marine conservation programs. Generalizations based on geographic proximity, taxonomy, or life history characteristics provide little predictive power in determining overall patterns of connectivity, and therefore offer little in terms of delineating boundaries for marine spatial management areas. Here, we provide a case study of 27 taxonomically and ecologically diverse species (including reef fishes, marine mammals, gastropods, echinoderms, cnidarians, crustaceans, and an elasmobranch that reveal four concordant barriers to dispersal within the Hawaiian Archipelago which are not detected in single-species exemplar studies. We contend that this multispecies approach to determine concordant patterns of connectivity is an objective and logical way in which to define the minimum number of management units and that EBM in the Hawaiian Archipelago requires at least five spatially managed regions.

  16. Algae Based Carbon Capture and Utilization feasibility study : - initial analysis of carbon capture effect based on Zhoushan case pre-study in China

    OpenAIRE

    Sen, Cong

    2012-01-01

    This pre-feasibility study was taken out by the co-operation with Zhejiang University, the CEU lab in Zhejiang University is taking researches of the algae based carbon dioxide capture technology, this report mainly aims to evaluate the GHG mitigation effect of this technology and give suggestions.   This study was carried out at Zhejiang University based on the Zhoushan islands waste incineration power plant project, the report presents the initial feasibility study for the algae based carbo...

  17. Data Mining for Web-Based Support Systems: A Case Study in e-Custom Systems

    Science.gov (United States)

    Razmerita, Liana; Kirchner, Kathrin

    This chapter provides an example of a Web-based support system (WSS) used to streamline trade procedures, prevent potential security threats, and reduce tax-related fraud in cross-border trade. The architecture is based on a service-oriented architecture that includes smart seals and Web services. We discuss the implications and suggest further enhancements to demonstrate how such systems can move toward a Web-based decision support system with the support of data mining methods. We provide a concrete example of how data mining can help to analyze the vast amount of data collected while monitoring the container movements along its supply chain.

  18. Scan-Based Attack on Stream Ciphers:A Case Study on eSTREAM Finalists

    Institute of Scientific and Technical Information of China (English)

    邹敏辉; 马坤; 吴剀劼; 沙行勉

    2014-01-01

    Scan-based design for test (DFT) is a powerful and the most popular testing technique. However, while scan-based DFT improves test efficiency, it also leaves a side channel to the privacy information stored in the chip. This paper investigates the side channel and proposes a simple but powerful scan-based attack that can reveal the key and/or state stored in the chips that implement the state-of-the-art stream ciphers with less than 85 scan-out vectors.

  19. Qualitative Event-based Diagnosis with Possible Conflicts: Case Study on the Third International Diagnostic Competition

    Data.gov (United States)

    National Aeronautics and Space Administration — We describe two model-based diagnosis algo- rithms entered into the Third International Diag- nostic Competition. We focus on the first diag- nostic problem of the...

  20. Using Web-Based Course to Enhance Educational Process at Jordan Universities – A Case Study

    OpenAIRE

    El-Seoud, Samir A.; Al-Khasawneh, Baha; Awajan, Arafat

    2007-01-01

    This paper shows that the use of web-based instruction in IT undergraduate distancelearning program is one vivid demonstration of the potential of using technology in instruction. The paper also shows that using web-based course strongly contributed to the effectiveness of distance learning by improving the quality of students' comprehension in areas of critical thinking, problem solving, decision-making ability, aptitude for detail, written communication, knowledge of information, and abilit...

  1. Value based pricing in outsourcing - a case study from the vendor's perspective

    OpenAIRE

    Ojanen, Karoliina

    2013-01-01

    Research Objective The objective of this is to find value based pricing models for a business process outsourcing service provider. Due to the intangible nature of services, it is more difficult for the customers to understand what they really are paying for. Variety and simultaneity in service process makes the pricing of services challenging. In value-based pricing, the price is determined by the customers' value perception of the product or service in question. The key value drivers ...

  2. Evaluation of Comprehensive Agricultural Production Capacity Based on Factor Analysis: A Case Study of Hunan Province

    OpenAIRE

    Rao, Wenzhu

    2013-01-01

    Based on the basic connotation of comprehensive agricultural production capacity, this article establishes the comprehensive agricultural production capacity indicator system on the basis of statistics. This indicator system consists of 5 parts (input scale of factors, output scale of factors, output rate of factors, ability to resist disaster and ensure production, and modern operation level) and 14 specific indicators. Based on factor analysis method, we use this indicator system to conduct...

  3. Developing a Methodology for Supplier Base Reduction : A Case Study at Dynapac GmbH

    OpenAIRE

    Böris, Elin; Hall, Vendela

    2015-01-01

    Dynapac GmbH is a manufacturer of road construction equipment and has historically been acquired and merged with several companies, resulting in an expansion of their supplier base. Currently, they are experiencing a large supplier base within direct material causing a decrease in the effectiveness and efficiency in the management of the suppliers. Dynapac GmbH therefore wishes to lower the number of suppliers in order to obtain desired effects, such as cost savings, reduction of administrati...

  4. Case study of a project-based learning course in civil engineering design

    OpenAIRE

    Gavin, Kenneth

    2011-01-01

    This paper describes the use of project-based learning to teach design skills to civil engineering students at University College Dublin (UCD). The paper first considers the development of problem-based leaning (PBL) as a tool in higher education. The general issues to be considered in the design of the curriculum for a PBL module are reviewed. Consideration of the literature on the application of PBL in civil engineering suggests that, because of the hierarchical nature of engineering educat...

  5. 55 cases of allergic reactions to hair dye: a descriptive, consumer complaint-based study

    DEFF Research Database (Denmark)

    Søsted, H; Agner, T; Andersen, Klaus Ejner;

    2002-01-01

    themselves, and adverse reactions to hair dye may not necessarily be recorded by the health care system, unless the reactions are especially severe. Based on this assumption, we suspected that hair dye dermatitis was occurring more frequently than reported in the literature. Consumer complaint-based data...... in the health care system. The frequency of allergic contact dermatitis resulting from hair dye is likely to be underestimated. New methods to survey the frequency of adverse reactions should be considered....

  6. Toward Sustainable Practice of Market-Based Waste Management System Case Study in Sragen Regency, Indonesia

    OpenAIRE

    Harno; Dote, Yutaka; Sekito, Tomoo; Maryati, Sri

    2013-01-01

    Markets are the second largest generator of municipal solid waste after households. Research aims to measure the average daily waste generation, to determine waste composition, to measure the efficacy of market-based waste management, to identify the factors influencing market waste generation, to explain the parameters of market waste generation, and to make policy recommendations toward sustainable practice of a market-based waste management system in Sragen Regency has been conducted at Ge...

  7. Satellite remote sensing of cloud base height for convective cloud fiels: A case study

    OpenAIRE

    Meerkötter, Ralf; Zinner, Tobias

    2007-01-01

    A method is proposed for estimating base heights of convective clouds from satellite data. The approach takes advantage of the fact that convective water clouds appear as geometrically and optically thin clouds near an approximately constant condensation level in their earliest stage of growth and that deriving geometrical thicknesses for such thin clouds is less error prone. Striking is the fact that the method also provides the base height for clouds with large vertical extensions and high ...

  8. A Conservation-Based Approach to Compensation for Livestock Depredation: The Florida Panther Case Study.

    Science.gov (United States)

    Jacobs, Caitlin E; Main, Martin B

    2015-01-01

    Calf (Bos taurus) depredation by the federally endangered Florida panther (Puma concolor coryi) on ranches in southwest Florida is an important issue because ranches represent mixed landscapes that provide habitat critical to panther recovery. The objectives of this study were to (1) quantify calf depredation by panthers on two ranches in southwest Florida, and (2) develop a habitat suitability model to evaluate the quality of panther hunting habitat on ranchlands, assess whether the model could predict predation risk to calves, and discuss its potential to be incorporated into an incentive-based compensation program. We ear-tagged 409 calves with VHF transmitters on two ranches during 2011-2013 to document calf mortality. We developed a model to evaluate the quality of panther hunting habitat on private lands in southwest Florida using environmental variables obtained from the Florida Natural Areas Inventory (FNAI) Cooperative Landcover Database and nocturnal GPS locations of panthers provided by the Florida Fish and Wildlife Conservation Commission (FWC). We then tested whether the model could predict the location of calf depredation sites. Tagged calf loss to panthers varied between the two ranches (0.5%/yr to 5.3%/yr) and may have been influenced by the amount of panther hunting habitat on each ranch as the ranch that experienced higher depredation rates contained a significantly higher probability of panther presence. Depredation sites of tagged calves had a significantly greater probability of panther presence than depredation sites of untagged calves that were found by ranchers in open pastures. This suggests that there may be more calves killed in high risk environments than are being found and reported by ranchers and that panthers can hunt effectively in open environments. It also suggests that the model may provide a means for evaluating the quality of panther hunting habitat and the corresponding risk of depredation to livestock across the landscape. We

  9. A Conservation-Based Approach to Compensation for Livestock Depredation: The Florida Panther Case Study.

    Directory of Open Access Journals (Sweden)

    Caitlin E Jacobs

    Full Text Available Calf (Bos taurus depredation by the federally endangered Florida panther (Puma concolor coryi on ranches in southwest Florida is an important issue because ranches represent mixed landscapes that provide habitat critical to panther recovery. The objectives of this study were to (1 quantify calf depredation by panthers on two ranches in southwest Florida, and (2 develop a habitat suitability model to evaluate the quality of panther hunting habitat on ranchlands, assess whether the model could predict predation risk to calves, and discuss its potential to be incorporated into an incentive-based compensation program. We ear-tagged 409 calves with VHF transmitters on two ranches during 2011-2013 to document calf mortality. We developed a model to evaluate the quality of panther hunting habitat on private lands in southwest Florida using environmental variables obtained from the Florida Natural Areas Inventory (FNAI Cooperative Landcover Database and nocturnal GPS locations of panthers provided by the Florida Fish and Wildlife Conservation Commission (FWC. We then tested whether the model could predict the location of calf depredation sites. Tagged calf loss to panthers varied between the two ranches (0.5%/yr to 5.3%/yr and may have been influenced by the amount of panther hunting habitat on each ranch as the ranch that experienced higher depredation rates contained a significantly higher probability of panther presence. Depredation sites of tagged calves had a significantly greater probability of panther presence than depredation sites of untagged calves that were found by ranchers in open pastures. This suggests that there may be more calves killed in high risk environments than are being found and reported by ranchers and that panthers can hunt effectively in open environments. It also suggests that the model may provide a means for evaluating the quality of panther hunting habitat and the corresponding risk of depredation to livestock across the

  10. Achieving Research Impact Through Co‐creation in Community‐Based Health Services: Literature Review and Case Study

    Science.gov (United States)

    JACKSON, CLAIRE; SHAW, SARA; JANAMIAN, TINA

    2016-01-01

    Policy Points: Co‐creation—collaborative knowledge generation by academics working alongside other stakeholders—is an increasingly popular approach to aligning research and service development.It has potential for “moving beyond the ivory towers” to deliver significant societal impact via dynamic, locally adaptive community‐academic partnerships.Principles of successful co‐creation include a systems perspective, a creative approach to research focused on improving human experience, and careful attention to governance and process.If these principles are not followed, co‐creation efforts may fail. Context Co‐creation—collaborative knowledge generation by academics working alongside other stakeholders—reflects a “Mode 2” relationship (knowledge production rather than knowledge translation) between universities and society. Co‐creation is widely believed to increase research impact. Methods We undertook a narrative review of different models of co‐creation relevant to community‐based health services. We contrasted their diverse disciplinary roots and highlighted their common philosophical assumptions, principles of success, and explanations for failures. We applied these to an empirical case study of a community‐based research‐service partnership led by the Centre of Research Excellence in Quality and Safety in Integrated Primary‐Secondary Care at the University of Queensland, Australia. Findings Co‐creation emerged independently in several fields, including business studies (“value co‐creation”), design science (“experience‐based co‐design”), computer science (“technology co‐design”), and community development (“participatory research”). These diverse models share some common features, which were also evident in the case study. Key success principles included (1) a systems perspective (assuming emergence, local adaptation, and nonlinearity); (2) the framing of research as a creative enterprise with human

  11. A multi-site, randomized study of strengths-based case management with substance-abusing parolees

    OpenAIRE

    Prendergast, Michael; Frisman, Linda; Sacks, Joann Y; Staton-Tindall, Michele; GREENWELL, LISA; Lin, Hsiu-Ju; Cartier, Jerry

    2011-01-01

    Objectives To test whether strengths-based case management provided during an inmate’s transition from incarceration to the community increases participation in community substance abuse treatment, enhances access to needed social services, and improves drug use, crime, and HIV risk outcomes. Methods In a multi-site trial, inmates (men and women) in four states (n = 812) were randomly assigned (within site) to receive either Transitional Case Management (TCM group), based on strengths-based p...

  12. Termination: A Case Study.

    Science.gov (United States)

    Friedberg, Ahron L

    2015-12-01

    In this article I posit and examine certain criteria and qualities for ending an analysis. The case study describes the end phase of a four-year psychoanalysis in which the patient's decision to move to another area forced the end of his analysis. We continued to explore and work through his core neurotic conflicts that included issues of competitive rivalry, dominance and submission, control, and anxiety about birth and death. A shift in the transference from me as a negative father to me as a supportive but competitive older brother was also examined in the context of ending treatment as well as other aspects of the transference. In addition, we analyzed the meaning of his ending treatment based on an extra-analytic circumstance. In discussing this phase of treatment, the definition and history of the term "termination" and its connotations are reviewed. Various criteria for completing an analysis are examined, and technical observations about this phase of treatment are investigated. It was found that while a significant shift in the transference occurred in this phase of the patient's analysis, conflicts related to the transference were not "resolved" in the classical sense. Terminating treatment was considered as a practical matter in which the patient's autonomy and sense of choice were respected and analyzed. PMID:26583444

  13. Development Of Location-Based Photo Sharing iPhone Application : A Case Study Breakit

    OpenAIRE

    Shrestha, Binit

    2013-01-01

    The primary purpose of the project was to build an outstanding location-based photo shar-ing iPhone application named Breakit for a start-up company named Eighty-Five Media Oy. The core functions of the application were displaying the photo feed based on the user’s current location and the ability to take photo, write some comments and upload to the Breakit server and other social media such as Twitter and Facebook. The main goal of the project was to develop the application and release it gl...

  14. Energy and Exergy Performances of Air-Based vs. Water-Based Heating and Cooling Systems: A Case Study of a Single-Family House

    DEFF Research Database (Denmark)

    Kazanci, Ongun Berk; Shukuya, Masanori; Olesen, Bjarne W.

    2016-01-01

    terms of energy and exergy. In addition to the energy and exergy input required at the heating and cooling plants, the energy use of auxiliary components (fans and pumps) also vary depending on the chosen terminal unit. In order to study the energy and exergy performances of air-based and water......Different indoor terminal units can be used to heat and cool indoor spaces. These terminal units mostly rely on convection and radiation heat transfer mechanisms but their relative ratios can vary significantly for air-based and water-based systems with implications on whole system performance, in......-based systems, an air heating and cooling system, and a radiant floor heating and cooling system were chosen, respectively. A single-family house was used as a case study assuming that different space heating and cooling systems were used to condition the indoor space of this house. In addition to the thermal...

  15. Paediatric leptospirosis: A population based case-control study from Chennai, India.

    Science.gov (United States)

    Narayanan, R; Sumathi, G; Prabhakaran, S G; Shanmughapriya, S; Natarajaseenivasan, K

    2016-01-01

    The surveillance in Chennai identified 134 children and 443 adults clinically suspected for leptospirosis. Of these, 35 (26.1%) children and 118 (26.6%) adults had laboratory confirmed diagnosis for leptospirosis. The paediatric leptospirosis exhibited a higher frequency of classic features of Weil's disease. The prevalent serovar encountered was Icterohaemorrhagiae with no difference in the pattern of infecting serovars between the two groups. Further, confirmation of diagnosis was achieved by polymerase chain reaction (PCR) with a positivity of 28.4% (specificity 96%). Univariate analysis showed significant association of paediatric leptospirosis with rat infestation (odds ratio 87.4). Thus, PCR facilitates early diagnosis of febrile illness among paediatric cases. PMID:27080780

  16. Familial correlations of onset age of hepatocellular carcinoma: a population-based case-control family study.

    Directory of Open Access Journals (Sweden)

    Li Liu

    Full Text Available There was lack of evidence for familial aggregation in onset age of hepatocellular carcinoma (HCC in Chinese population. We conducted a population-based case-control family study to examine familial correlation of age of HCC onset in Taixing, China.A total of 202 cases and 202 matched controls as well as their relatives were included in the study. Lifetime cumulative risks of HCC were estimated using the Kaplan-Meier approach. Cross ratios (CRs were obtained from stratified Cox proportional hazard models, to assess the familial correlation of onset age.The mean age of HCC onset was decreased as increasing number of HCC cases in a family. The onset age was the earliest for first-degree relatives, intermediate for second-degree relatives, and latest for non-blood relatives (spouse (log-rank test, P<0.01. The onset age was significantly correlated between probands and their relatives. In stratified Cox proportional hazard models, the CRs for the probands versus their fathers, mothers, siblings and uncles/aunts were 6.25 (95% confidence interval (CI: 1.84-21.25, 9.81 (95% CI: 1.24-77.56, 6.22 (95% CI: 1.37-28.36 and 3.24 (95% CI: 1.26-8.33, respectively. After adjustment for hepatitis B virus infection, the CRs remained significant.This current study suggested a significant correlation of onset age for HCC among blood relatives. Familial HCC cases yielded earlier age of onset and their relatives have higher HCC risk in early age, highlighting intensive surveillance should be start at an earlier age for individuals with family history of HCC.

  17. Study on wave energy resource assessing method based on altimeter data—A case study in Northwest Pacific

    Institute of Scientific and Technical Information of China (English)

    WAN Yong; ZHANG Jie; MENG Junmin; WANG Jing; DAI Yongshou

    2016-01-01

    Wave energy resource is a very important ocean renewable energy. A reliable assessment of wave energy resources must be performed before they can be exploited. Compared with wave model, altimeter can provide more accuratein situ observations for ocean wave which can be as a novel method for wave energy assessment. The advantage of altimeter data is to provide accurate significant wave height observations for wave. In order to develop characteristic and advantage of altimeter data and apply altimeter data to wave energy assessment, in this study, we established an assessing method for wave energy in local sea area which is dedicated to altimeter data. This method includes three parts including data selection and processing, establishment of evaluation indexes system and criterion of regional division. Then a case study of Northwest Pacific was performed to discuss specific application for this method. The results show that assessing method in this paper can assess reserves and temporal and spatial distribution effectively and provide scientific references for the siting of wave power plants and the design of wave energy convertors.

  18. A population-based case-crossover study of polyethylene glycol use and acute renal failure risk in the elderly

    Institute of Scientific and Technical Information of China (English)

    Nam-Kyong Choi; Yoosoo Chang; Sun-Young Jung; Yu-Kyong Choi; Joongyub Lee; Jin-Ho Lee; Ju-Young Kim; Byung-Joo Park

    2011-01-01

    AIM: To evaluate the possibility of an association between polyethylene glycol (PEG) and acute renal failure (ARF) in elderly patients using a health insurance claims database.METHODS: We conducted a population-based casecrossover study using information obtained from Korean Health Insurance Review and Assessment Service (HIRA)claims from January 1, 2005 to December 31, 2005(Seoul, Korea). The study population consisted of elderly patients who received PEG prior to experiencing their first ARF-related hospitalization from April 1, 2005 to December 31, 2005. For each patient, one case and two control periods were matched. PEG use in a 2- or 4-wk window period prior to hospitalization for ARF was compared with PEG use in two earlier 2- or 4-wk control window periods. Conditional logistic regression analysis was used to estimate odds ratios (ORs) and 95% CI, adjusting for concomitant uses of diuretics, angiotensin converting enzyme inhibitors, non-steroidal anti-inflammatory drugs,antibiotics, anti-cancer drugs, and contrast media.RESULTS: Within the HIRA database which contained 1 093 262 elderly patients, 1156 hospitalized ARF cases were identified. Among these cases, PEG was prescribed to 17 (1.5%) patients before hospitalization. The adjusted ORs when applying the 2- and 4-wk window periods were 0.4 (95% CI: 0.03-5.24) and 2.1 (95% CI:0.16-27.78), respectively.CONCLUSION: No increased risk of ARF was found in elderly PEG users. However, based on the limited number of study subjects, further analysis should be performed to confirm these results.

  19. Using EPAS[TM] to Evaluate School-Based Intervention Programs: GEAR UP. Case Study

    Science.gov (United States)

    ACT, Inc., 2007

    2007-01-01

    This brief examines how the ACT's EPAS[TM] (Educational Planning and Assessment System) can be used to evaluate school-based intervention programs. Specific evaluation considered is that of the federal government's Gaining Early Awareness and Readiness for Undergraduate Programs (GEAR UP), an initiative designed to increase the college awareness…

  20. Evaluating Automatic Speech Recognition-Based Language Learning Systems: A Case Study

    Science.gov (United States)

    van Doremalen, Joost; Boves, Lou; Colpaert, Jozef; Cucchiarini, Catia; Strik, Helmer

    2016-01-01

    The purpose of this research was to evaluate a prototype of an automatic speech recognition (ASR)-based language learning system that provides feedback on different aspects of speaking performance (pronunciation, morphology and syntax) to students of Dutch as a second language. We carried out usability reviews, expert reviews and user tests to…

  1. Biomimetic agent based modelling using male Frog calling behaviour as a case study

    DEFF Research Database (Denmark)

    Jørgensen, Søren V.; Demazeau, Yves; Christensen-Dalsgaard, Jakob;

    2014-01-01

    A new agent-based modelling tool has been developed to allow the modelling of populations of individuals whose interactions are characterised by tightly timed dynamics. The tool was developed to model male frog calling dynamics, to facilitate research into what local rules may be employed by indi...

  2. A Transformational Approach to VHDL and CDFG Based High-Level Synthesis: a Case Study

    NARCIS (Netherlands)

    Middelhoek, Peter F.A.; Mekenkamp, Gerhard E.; Molenkamp, Bert E.; Krol, Thijs

    1995-01-01

    In this paper, a novel multi-target design methodology based on the concepts of transformational design, and its application to the interlaced-to-progressive scan conversion (IPSC) problem, are discussed. Starting from a single high-level behavioral specification in VHDL a direction detector used in

  3. Inquiry-Based Learning Case Studies for Computing and Computing Forensic Students

    Science.gov (United States)

    Campbell, Jackie

    2012-01-01

    Purpose: The purpose of this paper is to describe and discuss the use of specifically-developed, inquiry-based learning materials for Computing and Forensic Computing students. Small applications have been developed which require investigation in order to de-bug code, analyse data issues and discover "illegal" behaviour. The applications are based…

  4. Mindfulness-Based Cognitive Therapy Applied to Binge Eating: A Case Study

    Science.gov (United States)

    Baer, Ruth A.; Fischer, Sarah; Huss, Debra B.

    2005-01-01

    Binge eating is a common problem associated with distress and dysfunction. Mindfulness-based interventions are attracting increasing attention, and the recent empirical literature suggests that they may be effective for a variety of disorders. Current theories about the etiology and maintenance of binge eating suggest that mindfulness training may…

  5. A Project-Based Learning Approach: A Case Study in China

    Science.gov (United States)

    Xu, Yueyu; Liu, Wenqi

    2010-01-01

    The goal of higher education is to cultivate graduates' creative capability, critical thinking skills, and other professional qualities. This paper describes a project-based course and its application in graduate-level education. This course is to improve students' creative capability, collaboration capability, and self-direction. It includes many…

  6. Marketing Need-Based Financial Aid Programs: An Institutional Case Study

    Science.gov (United States)

    Knight, Mary Beth

    2010-01-01

    Colleges and universities represent one of the most utilized sources of need-based financial aid information for students and families, and yet most research in access marketing is focused at the national and state levels. There is sparse published information about the effects of financial aid marketing observed through quantitative analysis, in…

  7. Optimizing Web-Based Instruction: A Case Study Using Poultry Processing Unit Operations

    Science.gov (United States)

    O' Bryan, Corliss A.; Crandall, Philip G.; Shores-Ellis, Katrina; Johnson, Donald M.; Ricke, Steven C.; Marcy, John

    2009-01-01

    Food companies and supporting industries need inexpensive, revisable training methods for large numbers of hourly employees due to continuing improvements in Hazard Analysis Critical Control Point (HACCP) programs, new processing equipment, and high employee turnover. HACCP-based food safety programs have demonstrated their value by reducing the…

  8. Expanding Omani Learners' Horizons through Project-Based Learning: A Case Study

    Science.gov (United States)

    Dauletova, Victoria

    2014-01-01

    As a relatively innovative teaching/learning approach in the Arabian Gulf region, in general, and in Oman, in particular, project-based learning requires progressive amendments and adaptations to the national culture of the learner. This article offers analysis of the current state of the approach in the local educational environment. Furthermore,…

  9. English Literature and Work-Based Learning: A Pedagogical Case Study

    Science.gov (United States)

    Eastman, Christine Angela

    2014-01-01

    This paper discusses a pilot project held at Middlesex University to enhance students' writing skills through literature teaching. It argues that literature teaching can offer a profound contribution to work-based learning and lifelong education: first, by showing students how effective arguments are constructed; second, by inspiring students…

  10. The Strategic Development of Learner Autonomy through Enquiry-Based Learning: A Case Study

    Science.gov (United States)

    Bramhall, Mike D.; Lewis, Justin; Norcliffe, Allan; Radley, Keith; Waldock, Jeff

    2010-01-01

    This paper reports on strategic developments to enhance student learner autonomy skills through the use of enquiry-based learning (EBL) in the design of higher education programmes. The UK's Sheffield Hallam University is a recognized Centre of Excellence in Teaching and Learning (CETL) in the field of developing learner autonomy. Central to the…

  11. Team-Based Learning in the Humanities Classroom: "Women's Environmental Writing" as a Case Study

    Science.gov (United States)

    Harde, Roxanne

    2015-01-01

    This essay presents the adaptation of Team-Based Learning (TBL) for a course that uses ecofeminist approaches to environmental literature. Developed originally for use in professional programs, TBL's cornerstones are permanent learning teams, preparation, application, and timely assessment (Michaelsen, Knight, & Fink, 2002). I wanted my…

  12. Analysing a Web-Based E-Commerce Learning Community: A Case Study in Brazil.

    Science.gov (United States)

    Joia, Luiz Antonio

    2002-01-01

    Demonstrates the use of a Web-based participative virtual learning environment for graduate students in Brazil enrolled in an electronic commerce course in a Masters in Business Administration program. Discusses learning communities; computer-supported collaborative work and collaborative learning; influences on student participation; the role of…

  13. A Case Study of District Decentralization and Site-Based Budgeting: Cordell Place School District.

    Science.gov (United States)

    Fermanich, Mark; Odden, Allan; Archibald, Sarah

    A previously high-ranking suburban school district with declining student achievement changed to site-based budgeting. The account of the change may also be a cautionary tale about change taken too rapidly. Although a poor economy, the annexation of two Department of Defense schools, and organizational stagnation helped to create lower student…

  14. Implementing Curriculum-Based Learning Portfolio: A Case Study in Taiwan

    Science.gov (United States)

    Chen, Shu-Chin Susan; Cheng, Yu-Pay

    2011-01-01

    The main purpose of this descriptive research is to examine and document the development of a curriculum-based learning portfolio model for children in a preschool for three-six-year-olds in Taiwan. Data collection methods adopted include classroom observation, in-depth interviews, questionnaires and documentation. Participants include a preschool…

  15. A research approach for quality based design of healthy foods: Dried broccoli as a case study

    NARCIS (Netherlands)

    Oliviero, T.; Verkerk, R.; Dekker, M.

    2013-01-01

    An approach for process design based on optimization of product quality attributes is presented. Adsorption drying of broccoli with retention of its health benefits is taken as an example to illustrate the approach. Related to its content of glucosinolates, broccoli has a high potential to reduce th

  16. Systems Thinking Tools as Applied to Community-Based Participatory Research: A Case Study

    Science.gov (United States)

    BeLue, Rhonda; Carmack, Chakema; Myers, Kyle R.; Weinreb-Welch, Laurie; Lengerich, Eugene J.

    2012-01-01

    Community-based participatory research (CBPR) is being used increasingly to address health disparities and complex health issues. The authors propose that CBPR can benefit from a systems science framework to represent the complex and dynamic characteristics of a community and identify intervention points and potential "tipping points." Systems…

  17. Childhood cancer and residential radon exposure - results of a population-based case-control study in Lower Saxony (Germany)

    International Nuclear Information System (INIS)

    A population-based case-control study on risk factors for childhood malignancies was used to investigate a previously reported association between elevated indoor radon concentrations and childhood cancer, with special regard to leukaemia. The patients were all children suffering from leukaemia and common solid tumours (nephroblastoma, neuroblastoma, rhabdomyosarcoma, central nervous system (CNS) tumours) diagnosed between July 1988 and June 1993 in Lower Saxony (Germany) and aged less than 15 years. Two population-based control groups were matched by age and gender to the leukaemia patients. Long-term (1 year) radon measurements were performed in those homes where the children had been living for at least 1 year, with particular attention being paid to those rooms where they had stayed most of the time. Due to the sequential study design, radon measurements in these rooms could only be done for 36% (82 leukaemias, 82 solid tumours and 209 controls) of the 1038 families initially contacted. Overall mean indoor radon concentrations (27 Bq m-3) were low compared with the measured levels in other studies. Using a prespecified cutpoint of 70 Bq m-3, no association with indoor radon concentrations was seen for the leukaemias (odds ratio (OR): 1.30; 95% confidence interval (95% CI): 0.32-5.33); however, the risk estimates were elevated for the solid tumours (OR: 2.61; 95% CI: 0.96-7.13), mainly based on 6 CNS tumours. We did not find any evidence for an association between indoor radon and childhood leukaemia, which is in line with a recently published American case-control study. There is little support for an association with CNS tumours in the literature. (orig.)

  18. Childhood cancer and residential radon exposure - results of a population-based case-control study in Lower Saxony (Germany)

    Energy Technology Data Exchange (ETDEWEB)

    Kaletsch, U.; Kaatsch, P.; Meinert, R.; Schuez, J.; Michaelis, J. [Institut fuer Medizinische Statistik und Dokumentation, Johannes-Gutenberg-Universitaet, D-55101 Mainz (Germany); Czarwinski, R. [Bundesamt fuer Strahlenschutz, Fachbereich ST, D-10318 Berlin (Germany)

    1999-09-01

    A population-based case-control study on risk factors for childhood malignancies was used to investigate a previously reported association between elevated indoor radon concentrations and childhood cancer, with special regard to leukaemia. The patients were all children suffering from leukaemia and common solid tumours (nephroblastoma, neuroblastoma, rhabdomyosarcoma, central nervous system (CNS) tumours) diagnosed between July 1988 and June 1993 in Lower Saxony (Germany) and aged less than 15 years. Two population-based control groups were matched by age and gender to the leukaemia patients. Long-term (1 year) radon measurements were performed in those homes where the children had been living for at least 1 year, with particular attention being paid to those rooms where they had stayed most of the time. Due to the sequential study design, radon measurements in these rooms could only be done for 36% (82 leukaemias, 82 solid tumours and 209 controls) of the 1038 families initially contacted. Overall mean indoor radon concentrations (27 Bq m{sup -3}) were low compared with the measured levels in other studies. Using a prespecified cutpoint of 70 Bq m{sup -3}, no association with indoor radon concentrations was seen for the leukaemias (odds ratio (OR): 1.30; 95% confidence interval (95% CI): 0.32-5.33); however, the risk estimates were elevated for the solid tumours (OR: 2.61; 95% CI: 0.96-7.13), mainly based on 6 CNS tumours. We did not find any evidence for an association between indoor radon and childhood leukaemia, which is in line with a recently published American case-control study. There is little support for an association with CNS tumours in the literature. (orig.)

  19. An approach to multicore parallelism using functional programming: A case study based on Presburger Arithmetic

    DEFF Research Database (Denmark)

    Dung, Phan Anh; Hansen, Michael Reichhardt

    2015-01-01

    In this paper we investigate multicore parallelism in the context of functional programming by means of two quantifier-elimination procedures for Presburger Arithmetic: one is based on Cooper’s algorithm and the other is based on the Omega Test. We first develop correct-by-construction prototype...... into account negative factors such as cache misses, garbage collection and overhead due to task creations, because such factors may introduce sequential bottlenecks with severe consequences for the parallel efficiency. The experiments were conducted using the functional programming language F# and .NET...... reveals more general applicable techniques and guideline for deriving parallel algorithms from sequential ones in the context of data-intensive tree algorithms. The obtained insights should apply for any strict and impure functional programming language. Furthermore, the results obtained for the exact...

  20. Semantics-Based Compiling: A Case Study in Type-Directed Partial Evaluation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Vestergaard, René

    We illustrate a simple and effective solution to semantics-based compiling. Our solution is based on ldquotype-directed partial evaluationrdquo, and – our compiler generator is expressed in a few lines, and is efficient; – its input is a well-typed, purely functional definitional interpreter in the......, annotations, etc.) than the typed lambda-calculus. In particular, it uses no other program analysis than traditional type inference. The overall simplicity and effectiveness of the approach has encouraged us to write this paper, to illustrate this genuine solution to denotational semantics...... specializing a definitional interpreter with respect to the program. Specialization is carried out using type-directed partial evaluation, which is a mild version of partial evaluation akin to lambda-calculus normalization. Our definitional interpreter follows the format of denotational semantics, with a clear...

  1. Semantics-based compiling: A case study in type-directed partial evaluation

    DEFF Research Database (Denmark)

    Danvy, Olivier; Vestergaard, René

    We illustrate a simple and effective solution to semantics-based compiling. Our solution is based on ldquotype-directed partial evaluationrdquo, and – our compiler generator is expressed in a few lines, and is efficient; – its input is a well-typed, purely functional definitional interpreter in the......, annotations, etc.) than the typed lambda-calculus. In particular, it uses no other program analysis than traditional type inference. The overall simplicity and effectiveness of the approach has encouraged us to write this paper, to illustrate this genuine solution to denotational semantics...... specializing a definitional interpreter with respect to the program. Specialization is carried out using type-directed partial evaluation, which is a mild version of partial evaluation akin to lambda-calculus normalization. Our definitional interpreter follows the format of denotational semantics, with a clear...

  2. A Case Study of MasterMind Chess: Comparing Mouse/Keyboard Interaction with Kinect-Based Gestural Interface

    Directory of Open Access Journals (Sweden)

    Gabriel Alves Mendes Vasiljevic

    2016-01-01

    Full Text Available As gestural interfaces emerged as a new type of user interface, their use has been vastly explored by the entertainment industry to better immerse the player in games. Despite being mainly used in dance and sports games, little use was made of gestural interaction in more slow-paced genres, such as board games. In this work, we present a Kinect-based gestural interface for an online and multiplayer chess game and describe a case study with users with different playing skill levels. Comparing the mouse/keyboard interaction with the gesture-based interaction, the results of the activity were synthesized into lessons learned regarding general usability and design of game control mechanisms. These results could be applied to slow-paced board games like chess. Our findings indicate that gestural interfaces may not be suitable for competitive chess matches, yet it can be fun to play while using them in casual matches.

  3. The role of taxation policy and incentives in wind-based distributed generation projects viability. Ontario case study

    International Nuclear Information System (INIS)

    Taxation policy and incentives play a vital role in wind-based distributed generation projects viability. In this paper, a thorough techno-economical evaluation of wind-based distributed generation projects is conducted to investigate the effect of taxes and incentives in the economic viability of investments in this sector. This paper considers the effects of Provincial income taxes, capital cost allowance (CCA), property taxes, and wind power production Federal incentives. The case study is conducted for different wind turbines and wind speed scenarios. Given turbine and wind speed data, the Capacity Factor (CF) of each turbine and wind speed scenario was calculated. Net Present Value (NPV) and Internal Rate of Return (IRR) for different scenarios were then used to assess the project's viability considering Ontario Standard Offer Program (SOP) for wind power. (author)

  4. Implementing condition-based maintenance using modeling and simulation: a case study of a permanent magnet synchronous motor

    Directory of Open Access Journals (Sweden)

    Jabid Quiroga Méndez

    2011-05-01

    Full Text Available  This paper introduces condition-based maintenance (CBM architecture regarding an electrical application. Appropriate and efficient fault detection constitutes one of the major challenges associated with CBM and a model-based approach constitutes the way to achieve it. A case study using a permanent magnet synchronous motor (PMSM is presented to illustrate implementing CBM using a neural network motor model. CBM may be implemented in real time using Matlab and dSpace. The difference between line currents' negative sequence components, predicted by a multilayer neural network, and the current values acquired from the motor is used as fault indicator. Experimental results have shown the efficiency of the proposed model in detecting several stator winding short faults in differing load conditions and fault severity, obtaining up to 95% reliability. 

  5. Multinomial logistic regression approach to haplotype association analysis in population-based case-control studies

    OpenAIRE

    Kao Jau-Tsuen; Chen Yi-Hau

    2006-01-01

    Abstract Background The genetic association analysis using haplotypes as basic genetic units is anticipated to be a powerful strategy towards the discovery of genes predisposing human complex diseases. In particular, the increasing availability of high-resolution genetic markers such as the single-nucleotide polymorphisms (SNPs) has made haplotype-based association analysis an attractive alternative to single marker analysis. Results We consider haplotype association analysis under the popula...

  6. Complexity-based learning and teaching: a case study in higher education

    OpenAIRE

    Fabricatore, Carlo; López, Ximena

    2014-01-01

    This paper presents a learning and teaching strategy based on complexity science and explores its impacts on a higher education game design course. The strategy aimed at generating conditions fostering individual and collective learning in educational complex adaptive systems, and led the design of the course through an iterative and adaptive process informed by evidence emerging from course dynamics. The data collected indicate that collaboration was initially challenging for students, but c...

  7. Mobile devices for community-based REDD+ monitoring: A case study for Central Vietnam

    OpenAIRE

    Pratihast, A.K.; M. Herold; Avitabile, V.; Bruin, de, R.J.; Bartholomeus, H; Souza Jr., C.M.; Ribbe, L.

    2013-01-01

    Monitoring tropical deforestation and forest degradation is one of the central elements for the Reduced Emissions from Deforestation and Forest Degradation in developing countries (REDD+) scheme. Current arrangements for monitoring are based on remote sensing and field measurements. Since monitoring is the periodic process of assessing forest stands properties with respect to reference data, adopting the current REDD+ requirements for implementing monitoring at national levels is a challengin...

  8. Mobile Devices for Community-Based REDD+ Monitoring: A Case Study for Central Vietnam

    OpenAIRE

    Carlos M. Souza Jr.; Lars Ribbe; Harm Bartholomeus; Sytze de Bruin; Valerio Avitabile; Martin Herold; Arun Kumar Pratihast

    2012-01-01

    Monitoring tropical deforestation and forest degradation is one of the central elements for the Reduced Emissions from Deforestation and Forest Degradation in developing countries (REDD+) scheme. Current arrangements for monitoring are based on remote sensing and field measurements. Since monitoring is the periodic process of assessing forest stands properties with respect to reference data, adopting the current REDD+ requirements for implementing monitoring at national levels is a challengin...

  9. Internet-based teleoperation: A case study - toward delay approximation and speed limit module

    OpenAIRE

    Shengtong, Zhong; Le Parc, Philippe; Vareille, Jean

    2007-01-01

    This paper presents the internet-based remote control of mobile robot. To face unpredictable Internet delays and possible connection rupture, a direct teleoperation architecture with “Speed Limit Module” (SLM) and “Delay Approximator” (DA) is proposed. This direct control architecture guarantees the path error of the robot motion is restricted within the path error tolerance of the application. Experiment results show the effectiveness and applicability of this direct internet control archite...

  10. Employees’ Satisfaction Assessment Based on Fuzzy Logic: A case study of Bandar Abbas Oil Refining Company

    OpenAIRE

    Khazaki, Hamid reza

    2013-01-01

    Employees satisfaction is a pre-condition for increasing productivity and attention to it is a success factor for excellent organizations. This paper presents a new approach for employees satisfaction assessment (ESA) based on fuzzy logic. In the process of ESA there is an element of vagueness or fuzziness associated with inputs that they are language terms. Also, it can be helpful for management having a model to prioritize dissatisfaction key factors according to satisfaction level and weig...

  11. Creative-based strategies in small and medium-sized cities: some European study cases

    OpenAIRE

    Tomaz, Elisabete; Selada, Catarina; da Cunha, Inês Vilhena

    2011-01-01

    During the last decades, creative and cultural approaches have been implemented in regional and urban development strategies as key drivers for competitiveness and growth. However, research literature tends to focus mainly in big cities and metropolis, not recognizing the potential of small cities in intermediate and rural regions in fostering territorial cohesion. Nevertheless, public policies based on creativity and innovation are being experienced in non-metropolitan and rural contexts aro...

  12. FPGA-based I and C Applications in NPPs Modernization Projects: Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Andrashov, Anton A.; Sklayar, Vladimr V.; Siora, Alexander A. [Research and Production Corporation Radiy, Kirovaograd (Ukraine)

    2014-08-15

    Instrumentation and Control systems represent one of several most important parts of each Nuclear Power Plant (NPP). Instrumentation and Control modernization projects are performed in the context and to support the overall NPP goals, objectives, and internal and external commitments. The goals and objectives of NPPs are defined substantially by the utilities long-term and short-term business plans. FPGA-based Instrumentation and Control applications may contribute to successful implementation of NPPs Instrumentation and Control modernization projects.

  13. An inquiry-based approach to Maxwell distribution: a case study with engineering students

    International Nuclear Information System (INIS)

    The concept of distribution is a fundamental component of statistical thinking. This paper describes a teaching approach for it that uses a specific activity related to the field of statistical mechanics. The concept of the velocity distribution of a particle system is dealt with using an inquiry-based approach involving an experimental examination of Maxwell's distribution. Some outcomes of a teaching experiment held at the Faculty of Engineering of the University of Palermo, Italy are described. (paper)

  14. A MVC framework for policy-based adaptation of workflow processes: A case study on confidentiality

    OpenAIRE

    Geebelen, Kristof; Kulikowski, Eryk; Truyen, Eddy; Joosen, Wouter

    2010-01-01

    Most work on adaptive workflows offers insufficient flexibility to enforce complex policies regarding dynamic, evolvable and robust workflows. In addition, many proposed approaches require customized workflow engines. This paper presents a portable framework for realistic enforcement of dynamic adaptation policies in business processes. The framework is based on the Model-View-Controller (MVC) pattern, commonly used for adding dynamism to web pages. To enhance reusability, our approach suppor...

  15. Web-Based Asynchronous Teleconsulting for Consumers in Colombia: A Case Study

    OpenAIRE

    Valenzuela, José Ignacio; Arguello, Arturo; Cendales, Juan Gabriel; Rizo, Carlos A

    2007-01-01

    Background Fourteen years after the reform to Colombia’s health system, the promises of universality, improved equity, efficiency, and better quality of care have not materialized. Remote areas remain underserved and access to care very limited. Recognizing teleconsultation as an effective way to improve access to health care and health information, a noncommercial open-access Web-based application for teleconsultation called Doctor Chat was developed. Objective The objective was to report th...

  16. Community-Based Coastal Resource Management (CB-CRM): a Case Study f Mariveles, Bataan, Philippines

    OpenAIRE

    Andrew Lou L. Mungcal

    2013-01-01

    This paper addressed the issue of sustainable coastal resource management through a successful Community-Based Coastal Resource Management (CB-CRM) Program in the Municipality of Mariveles, province of Bataan in the Philippines. The paper investigated how governance and institutional and legislative framework, and the concept of sustainable development complemented each other to promote good local eco-governance in the management and protection of finite local marine resources. Specifically, ...

  17. Agent-based modelling as scientific method: a case study analysing primate social behaviour

    OpenAIRE

    Bryson, Joanna J.; Ando, Yasushi; Lehmann, Hagen

    2007-01-01

    A scientific methodology in general should provide two things: first, a means of explanation and, second, a mechanism for improving that explanation. Agent-based modelling (ABM) is a method that facilitates exploring the collective effects of individual action selection. The explanatory force of the model is the extent to which an observed meta-level phenomenon can be accounted for by the behaviour of its micro-level actors. This article demonstrates that this methodology can be applied to th...

  18. Assessment challenges in competency-based education: A case study in health professions education.

    Science.gov (United States)

    Fitzgerald, James T; Burkhardt, John C; Kasten, Steven J; Mullan, Patricia B; Santen, Sally A; Sheets, Kent J; Tsai, Antonius; Vasquez, John A; Gruppen, Larry D

    2016-05-01

    There is a growing demand for health sciences faculty with formal training in education. Addressing this need, the University of Michigan Medical School created a Master in Health Professions Education (UM-MHPE). The UM-MHPE is a competency-based education (CBE) program targeting professionals. The program is individualized and adaptive to the learner's situation using personal mentoring. Critical to CBE is an assessment process that accurately and reliably determines a learner's competence in educational domains. The program's assessment method has two principal components: an independent assessment committee and a learner repository. Learners submit evidence of competence that is evaluated by three independent assessors. The assessments are presented to an Assessment Committee who determines whether the submission provides evidence of competence. The learner receives feedback on the submission and, if needed, the actions needed to reach competency. During the program's first year, six learners presented 10 submissions for review. Assessing learners in a competency-based program has created challenges; setting standards that are not readily quantifiable is difficult. However, we argue it is a more genuine form of assessment and that this process could be adapted for use within most competency-based formats. While our approach is demanding, we document practical learning outcomes that assess competence. PMID:26052881

  19. Objectivist case study research

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Fachner, Jörg

    2016-01-01

    In order to comprehend the impact of music therapy or music therapy processes, a researcher might look for an approach where the topic under investigation can be understood within a broader context. This calls for a rich inclusion of data and consequently a limited number of participants and may be...... achieved through the use of objectivist case study research. The strength of the case study design is that it allows for uncovering or suggesting causal relationships in real-life settings through an intensive and rich collection of data. According to Hilliard (1993), the opposite applies for extensive...... designs, in which a small amount of data is gathered on a large number of subjects. With the richness of data, the intensive design is ―the primary pragmatic reason for engaging in single-case or small N research‖ (p. 374) and for working from an idiographic rather than a nomothetic perspective....

  20. A study of urban traffic based on the temporal maps: the case of Guangzhou City

    Institute of Scientific and Technical Information of China (English)

    Li Wenling; Li Yawen; Li Shangzhi; Tang Yuanfang

    2008-01-01

    Temporal map is an isoehronal map taking time as a measuring unit. It traces out the isochrones according to the discrepancy of the time distance between the different sites from the outside of the city and the down town. It can be clear and intuitional to show the different temporal relationships between the outside of the city and the city centre with the temporal map. The problem of traffic congestion, with its potential for urban chaos, has increased dramatically with a growing number of vehicles and the continuing aerial expansion of Guangzhou. Both transit rid-ers and drivers find it is a great difficulty to try to acquire the necessary information.from urban spatial movements.Valuable time is lost due to the absence of good transportation information. So, the paper analyzes a case in Guang-zhou communication with Geographic Information System (GIS), and uses the most popular vehicles, including buses and taxis that are used to measure the temporal distance in the city, and then proposes the design of a new map that better reflects the status of urban communication, and attempts to change the relationship between one point and another point of travel. Reducing the amount of time allocated to such, often complex, movements. This paper also points out the obstacles associated with Guangzhou's existing traffic congestion, and puts forward a strategy aimed at better defining the need of linking the temporal map to spatial map of Guangzhou.

  1. Optimal DNA Pooling-Based Two-Stage Designs in Case-Control Association Studies

    OpenAIRE

    Zhao, Yihong; Wang, Shuang

    2008-01-01

    Study cost remains the major limiting factor for genome-wide association studies due to the necessity of genotyping a large number of SNPs for a large number of subjects. Both DNA pooling strategies and two-stage designs have been proposed to reduce genotyping costs. In this study, we propose a cost-effective, two-stage approach with a DNA pooling strategy. During stage I, all markers are evaluated on a subset of individuals using DNA pooling. The most promising set of markers is then evaluat...

  2. Environmental tax on products and services based on their carbon footprint: A case study of the pulp and paper sector

    International Nuclear Information System (INIS)

    The main aim of this work is to define an environmental tax on products based on their carbon footprint. We examine the relevance of life cycle analysis (LCA) and environmentally extended input–output analysis (EIO) as methodological tools for identifying the emission intensities on which the tax is based. The price effects of the tax and the policy implications of considering non-CO2 greenhouse gases (GHG) are also analyzed. The results from the case study on pulp production show that the environmental tax rate based on LCA (1.8%) is higher than both EIO approaches (0.8 and 1.4% for product and industry, respectively), but they are of the same order of magnitude. Although LCA is more product specific and provides a more detailed analysis, we recommend EIO as a more relevant approach to applying an economy-wide environmental tax. If an environmental tax were applied to non-CO2 GHG instead to CO2 alone, the tax would greatly affects sectors such as agriculture, mining of coal, extraction of peat, and food. Therefore, it is worthwhile for policy-makers to pay attention to the implications of considering either a CO2 tax or a global GHG emissions tax in order to make their policy measures effective and meaningful. - Highlights: ► Carbon footprints of products and services are modeled using EIO and LCA. ► Environmental taxes are introduced based on the estimated emission intensities. ► The effect of excluding non-GHG and its policy implications is discussed. ► Emission intensity and environmental tax are higher in LCA than EIO for the analyzed case study of pulp and paper production. ► EIO is more relevant than LCA for economy wide environmental tax application.

  3. Statin use and the risk of colorectal cancer:A population-based case-control study

    Institute of Scientific and Technical Information of China (English)

    Meng-Hsuan Cheng; Hui-Fen Chiu; Shu-Chen Ho; Shang-Shyue Tsai; Trong-Neng Wu; Chun-Yuh Yang

    2011-01-01

    AIM: Toinvestigatewhethertheuseo.. Statinsisassoci-o investigate wwhether the use ofstatins is associated wwith colorectal cancer risk. METHODS: We conducted a population-based case-control study in Taiwwan. Data wwere retrospectively collected f..rom the Taiwwan National Health Insurance Research Database. Cases consisted of.. All patients wwho were aged 50 years and older and had a first-time diagnosis of.. Colorectal cancer betwween the period 2005 and 2008. The controls matched to cases by age, sex, and index date. Adjusted odds ratios (Ors) and 95% confidence intervals (Cis) were estimated using multiple logistic regression. RESULTS: We examined 1156 colorectal cancer cases and 4624 controls. The unadjusted Ors .or any statin prescription wwas 1.10 (95% CI=0.94-1.30)andthead- andthead-=1.330) and the adjusted OR 1.09 (95% CI=0.91-1.30).Whenstatin Whenstatin=Whenstatin0.91-1.330). When statin use categorized by cumulative dose, the adjusted Ors wwere 0.99 (95% CI=0.78-1.27).orthegroupwith ith=ith0.778-1.277) or the group wwith cumulative statin use beloww 105 def..ined daily doses (DDDs); 1.077 (95% CI=0.78-1.49) .orthegroupwith ith=ith0.778-or the group cumulative statin use betwween 106 and 298.66 DDDs; and 1.330 (95% CI=0.96-1.75).orthegroupwithcu- ithcu-=1.775) or the group wwith cumulative statin use of. 298.66 DDDs or more compared with nonusers. CONCLUSION: This study does not provide support for a protective effect of statins against colorectal cancer.

  4. A Case Study of Nanofiltration Using an Irreversible Thermodynamics-Based Model

    OpenAIRE

    G. R. Vakili-Nezhaad; Z. Akbari

    2012-01-01

    The extended Spiegler-Kedem model that can be solved by using genetic algorithm (GA) has been used for study of the rejection of charged and uncharged solutes in a nanofiltration process. In this work, the accuracy and applicability of this model were tested with the data obtained from the nanofiltration of a real solution. The permeated solution was obtained from the whey ultrafiltration system (ultrafiltered whey). The studied process separates lactose and mineral salts from ultrafiltered w...

  5. An Approach to Composition Based on a Minimal Techno Case Study

    OpenAIRE

    Bougaïeff, Nicolas

    2013-01-01

    This dissertation examines key issues relating to minimal techno, a sub-genre of electronic dance music (EDM) that emerged in the early 1990s. These key issues are the aesthetics, composition, performance, and technology of minimal techno, as well as the economics of EDM production. The study aims to answer the following question. What is the musical and social significance of minimal techno production and performance? The study is conducted in two parts. The history of minimal music is ...

  6. Travel-related venous thrombosis: results from a large population-based case control study (MEGA study.

    Directory of Open Access Journals (Sweden)

    Suzanne C Cannegieter

    2006-08-01

    Full Text Available BACKGROUND: Recent studies have indicated an increased risk of venous thrombosis after air travel. Nevertheless, questions on the magnitude of risk, the underlying mechanism, and modifying factors remain unanswered. METHODS AND FINDINGS: We studied the effect of various modes and duration of travel on the risk of venous thrombosis in a large ongoing case-control study on risk factors for venous thrombosis in an unselected population (MEGA study. We also assessed the combined effect of travel and prothrombotic mutations, body mass index, height, and oral contraceptive use. Since March 1999, consecutive patients younger than 70 y with a first venous thrombosis have been invited to participate in the study, with their partners serving as matched control individuals. Information has been collected on acquired and genetic risk factors for venous thrombosis. Of 1,906 patients, 233 had traveled for more than 4 h in the 8 wk preceding the event. Traveling in general was found to increase the risk of venous thrombosis 2-fold (odds ratio [OR] 2.1; 95% confidence interval [CI] 1.5-3.0. The risk of flying was similar to the risks of traveling by car, bus, or train. The risk was highest in the first week after traveling. Travel by car, bus, or train led to a high relative risk of thrombosis in individuals with factor V Leiden (OR 8.1; 95% CI 2.7-24.7, in those who had a body mass index of more than 30 kg/m(2 (OR 9.9; 95% CI 3.6-27.6, in those who were more than 1.90 m tall (OR 4.7; 95% CI 1.4-15.4, and in those who used oral contraceptives (estimated OR > 20. For air travel these synergistic findings were more apparent, while people shorter than 1.60 m had an increased risk of thrombosis after air travel (OR 4.9; 95% CI 0.9-25.6 as well. CONCLUSIONS: The risk of venous thrombosis after travel is moderately increased for all modes of travel. Subgroups exist in which the risk is highly increased.

  7. LCA of biomass-based energy systems: A case study for Denmark

    International Nuclear Information System (INIS)

    Highlights: ► We assessed the environmental impacts of potential energy scenarios for DK. ► Domestic biomass resources were insufficient to cover the energy demand. ► Significant GHGs emissions reductions were achieved in the assessed scenarios. ► RME-biodiesel production for heavy transport resulted in high GW impact due to LUC. ► Eutrophication impact was an effect of crops cultivation and digestate use on land. -- Abstract: Decrease of fossil fuel consumption in the energy sector is an important step towards more sustainable energy production. Environmental impacts related to potential future energy systems in Denmark with high shares of wind and biomass energy were evaluated using life-cycle assessment (LCA). Based on the reference year 2008, energy scenarios for 2030 and 2050 were assessed. For 2050 three alternatives for supply of transport fuels were considered: (1) fossil fuels, (2) rapeseed based biodiesel, and (3) Fischer–Tropsch based biodiesel. Overall, the results showed that greenhouse gas emissions per PJ energy supplied could be significantly reduced (from 68 to 17 Gg CO2-eq/PJ) by increased use of wind and residual biomass resources as well as by electrifying the transport sector. Energy crops for production of biofuels and the use of these biofuels for heavy terrestrial transportation were responsible for most environmental impacts in the 2050 scenarios, in particular upstream impacts from land use changes (LUCs), fertilizer use and NOx emissions from the transport sector were critical. Land occupation (including LUC effects) caused by energy crop production increased to a range of 600–2100 × 106 m2/PJ depending on the amounts and types of energy crops introduced. Use of fossil diesel in the transport sector appeared to be environmentally preferable over biodiesel for acidification, aquatic eutrophication and land occupation. For global warming, biodiesel production via Fischer–Tropsch was comparable with fossil diesel.

  8. Data-based robust multiobjective optimization of interconnected processes: energy efficiency case study in papermaking.

    Science.gov (United States)

    Afshar, Puya; Brown, Martin; Maciejowski, Jan; Wang, Hong

    2011-12-01

    Reducing energy consumption is a major challenge for "energy-intensive" industries such as papermaking. A commercially viable energy saving solution is to employ data-based optimization techniques to obtain a set of "optimized" operational settings that satisfy certain performance indices. The difficulties of this are: 1) the problems of this type are inherently multicriteria in the sense that improving one performance index might result in compromising the other important measures; 2) practical systems often exhibit unknown complex dynamics and several interconnections which make the modeling task difficult; and 3) as the models are acquired from the existing historical data, they are valid only locally and extrapolations incorporate risk of increasing process variability. To overcome these difficulties, this paper presents a new decision support system for robust multiobjective optimization of interconnected processes. The plant is first divided into serially connected units to model the process, product quality, energy consumption, and corresponding uncertainty measures. Then multiobjective gradient descent algorithm is used to solve the problem in line with user's preference information. Finally, the optimization results are visualized for analysis and decision making. In practice, if further iterations of the optimization algorithm are considered, validity of the local models must be checked prior to proceeding to further iterations. The method is implemented by a MATLAB-based interactive tool DataExplorer supporting a range of data analysis, modeling, and multiobjective optimization techniques. The proposed approach was tested in two U.K.-based commercial paper mills where the aim was reducing steam consumption and increasing productivity while maintaining the product quality by optimization of vacuum pressures in forming and press sections. The experimental results demonstrate the effectiveness of the method. PMID:22147299

  9. Dynamic monitoring of lake based on HJ-CCD Images: a case study of Poyang Lake

    Science.gov (United States)

    Liu, Dong; Huang, Haiqing; Gong, Fang; Zhu, Qiankun; Yang, Xuefei

    2014-11-01

    Lake ecological environment is changing, driving by natural and human factors, and in turn influence people's living and producing. Therefore, dynamic monitoring of lake based on remote sensing technologies will play an important role to the disaster prevention and reduction work of lakes. In this paper, we expounded a series of work to realized monitor Poyang Lake dynamically by using HJ-CCD images. First, we did pretreatment to all HJ-CCD images, which mainly contain geometric correction, atmospheric correlation, image clipping, etc. Then, based on different features between water and non-water in different index layers, we extracted the covered area by water in different times from the corresponding HJ-CCD images, and we also extracted the true area through visual interpretation method. After that, by combining the water boundaries and DEM, we also estimated water level and water capacity in different times. Results of our work showed that the mean absolute error of water area extracted through remote technologies is 5.57%. The relationship of remote sensing areas and visual interpretation areas could be described as Strue = 0.8757*Sinterp + 110.24, with R2 = 0.9807. Besides, there was obvious relationship between water area and water capacity of Poyang Lake too, and the relations can be described with linear function. Based on such results, we can realize the dynamic estimation of Poyang Lake's area and capacity from daily gotten HJ-CCD image which covers the District of Poyang Lake. In other words, the results of this paper can provide decision basis for Poyang Lake's real-time, dynamic, economic monitoring.

  10. Web based map services for scientific tourism: a case study of eighteenth and nineteenth century Edinburgh.

    OpenAIRE

    Scholefield, Kerrie

    2008-01-01

    The purpose of this project was to develop a web based map service for scientific tourism of eighteenth and nineteenth century Edinburgh. The service had the potential to be used for two key purposes: an educational guide and a virtual tourist guide. The key to satisfying such a broad target audience was to make the website as user-friendly as possible; a key focus of this project. Similar projects were researched and no services with the same theme were discovered; suggesting a gap in the ma...

  11. RAROC Based Capital Budgeting and Performance Evaluation: A Case Study of Bank Capital Allocation

    OpenAIRE

    Christopher James

    1996-01-01

    This paper describes the RAROC system developed at Bank of America (B of A) in order to examine how risk-based capital allocation models work. I begin by discussing the economic rational for allocating capital in a diversified organization like the B of A. Drawing on recent work by Froot and Stein (1995) and Stein (1996), I argue that the capital budgeting process used by the B of A resembles the operation of an internal capital market in which businesses are allocated capital with the object...

  12. Optimization of biodiesel supply chains based on small farmers: A case study in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Leao, Raphael; Hamacher, Silvio

    2010-09-15

    The strategy adopted by the Brazilian Biodiesel Program is to base its fuel production on oilseeds acquired from small, family-owned farms in the poorest regions of the country, thereby fostering social inclusion and transfer of income. The success of the program depends on the development of a robust supply chain logistic structure, appropriate distribution of crop production, and investments in new oilseed crushing units. This article presents the development of a mathematical model for optimizing the production arrangements for the supply of a biodiesel plant sourced from family farms, taking into account agricultural, logistic, industrial and social aspects.

  13. To Stretch the Boundary of Secondary Metabolite Production in Plant Cell-Based Bioprocessing: Anthocyanin as a Case Study

    Directory of Open Access Journals (Sweden)

    Wei Zhang

    2004-01-01

    Full Text Available Plant cells and tissue cultures hold great promise for controlled production of a myriad of useful secondary metabolites on demand. The current yield and productivity cannot fulfill the commercial goal of a plant cell-based bioprocess for the production of most secondary metabolites. In order to stretch the boundary, recent advances, new directions and opportunities in plant cell-based bioprocessing, have been critically examined for the 10 years from 1992 to 2002. A review of the literature indicated that most of the R&D work was devoted predominantly to studies at an empirical level. A rational approach to molecular plant cell bioprocessing based on the fundamental understanding of metabolic pathways and their regulations is urgently required to stimulate further advances; however, the strategies and technical framework are still being developed. It is the aim of this review to take a step forward in framing workable strategies and technologies for molecular plant cell-based bioprocessing. Using anthocyanin biosynthesis as a case study, an integrated postgenomic approach has been proposed. This combines the functional analysis of metabolic pathways for biosynthesis of a particular metabolite from profiling of gene expression and protein expression to metabolic profiling. A global correlation not only can thus be established at the three molecular levels, but also places emphasis on the interactions between primary metabolism and secondary metabolism; between competing and/or complimentary pathways; and between biosynthetic and post-biosynthetic events.

  14. Work-based learning experiences help students with disabilities transition to careers: a case study of University of Washington projects.

    Science.gov (United States)

    Bellman, Scott; Burgstahler, Sheryl; Ladner, Richard

    2014-01-01

    This case study describes evidence-based practices employed by a collection of University of Washington projects that engage high school and postsecondary students with disabilities in work-based learning experiences such as industry and research internships, career development activities, job shadows, field trips, and mock interviews. The purpose of the article is two-fold. First, authors share best practices with others who wish to increase the participation of students with disabilities in work-based learning and thereby contribute to their academic and career success. The article discusses methods used to recruit students, employers and mentors, match students with specific opportunities, and prepare students for success. Second, authors share outcomes from studies regarding participation in these work-based learning opportunities, which include increased employment success, motivation to work toward a career, knowledge about careers and the workplace, job-related skills, ability to work with supervisors and coworkers, skills in self-advocating for accommodations, and perceived career options. PMID:24284672

  15. Nesidioblastosis: a case study.

    Science.gov (United States)

    Starbuck, A L

    1997-09-01

    Hypoglycemia is a common problem among neonates. Transient in nature, it usually resolves with an increase in glucose intake. However, as clinicians, we must recognize that prolonged hypoglycemia may be caused by increased insulin production. Nesidioblastosis is one cause of persistent hyperinsulinism of the newborn. This case study reviews fetal physiology, neonatal presentation, and treatment. PMID:9325879

  16. : Case studies: France

    OpenAIRE

    Bonerandi, Emmanuelle; Santamaria, Frédéric

    2005-01-01

    Case studies on territorial governance : urban region of Lyon (France) and the "Pays" policy (France) in the framework of the ESPON 2.3.2 project Études de cas sur la gouvernance territoriale : région urbaine de Lyon et politique des pays

  17. Web-based Tsunami Early Warning System: a case study of the 2010 Kepulaunan Mentawai Earthquake and Tsunami

    Science.gov (United States)

    Ulutas, E.; Inan, A.; Annunziato, A.

    2012-06-01

    This study analyzes the response of the Global Disasters Alerts and Coordination System (GDACS) in relation to a case study: the Kepulaunan Mentawai earthquake and related tsunami, which occurred on 25 October 2010. The GDACS, developed by the European Commission Joint Research Center, combines existing web-based disaster information management systems with the aim to alert the international community in case of major disasters. The tsunami simulation system is an integral part of the GDACS. In more detail, the study aims to assess the tsunami hazard on the Mentawai and Sumatra coasts: the tsunami heights and arrival times have been estimated employing three propagation models based on the long wave theory. The analysis was performed in three stages: (1) pre-calculated simulations by using the tsunami scenario database for that region, used by the GDACS system to estimate the alert level; (2) near-real-time simulated tsunami forecasts, automatically performed by the GDACS system whenever a new earthquake is detected by the seismological data providers; and (3) post-event tsunami calculations using GCMT (Global Centroid Moment Tensor) fault mechanism solutions proposed by US Geological Survey (USGS) for this event. The GDACS system estimates the alert level based on the first type of calculations and on that basis sends alert messages to its users; the second type of calculations is available within 30-40 min after the notification of the event but does not change the estimated alert level. The third type of calculations is performed to improve the initial estimations and to have a better understanding of the extent of the possible damage. The automatic alert level for the earthquake was given between Green and Orange Alert, which, in the logic of GDACS, means no need or moderate need of international humanitarian assistance; however, the earthquake generated 3 to 9 m tsunami run-up along southwestern coasts of the Pagai Islands where 431 people died. The post

  18. Are individual based models a suitable approach to estimate population vulnerability? - a case study

    Directory of Open Access Journals (Sweden)

    Eva Maria Griebeler

    2011-04-01

    Full Text Available European populations of the Large Blue Butterfly Maculinea arion have experienced severe declines in the last decades, especially in the northern part of the species range. This endangered lycaenid butterfly needs two resources for development: flower buds of specific plants (Thymus spp., Origanum vulgare, on which young caterpillars briefly feed, and red ants of the genus Myrmica, whose nests support caterpillars during a prolonged final instar. I present an analytically solvable deterministic model to estimate the vulnerability of populations of M. arion. Results obtained from the sensitivity analysis of this mathematical model (MM are contrasted to the respective results that had been derived from a spatially explicit individual based model (IBM for this butterfly. I demonstrate that details in landscape configuration which are neglected by the MM but are easily taken into consideration by the IBM result in a different degree of intraspecific competition of caterpillars on flower buds and within host ant nests. The resulting differences in mortalities of caterpillars lead to erroneous estimates of the extinction risk of a butterfly population living in habitat with low food plant coverage and low abundance in host ant nests. This observation favors the use of an individual based modeling approach over the deterministic approach at least for the management of this threatened butterfly.

  19. A Groupware-based Peer Review Process: An Exploratory Case Study

    Directory of Open Access Journals (Sweden)

    Bridget N. O'Connor

    1999-01-01

    Full Text Available This paper uses Lewin’s planned change theory and Rogers’ diffusion of innovation theory as lenses through which to describe what occurred in an organizationally flat, team-based organization when it rolled out a groupware-based peer review process. The Information Systems Department wanted to implement a high-level groupware product. The Human Resource Department wanted to enable team members to rate each other on their teambuilding skills as well as provide a criterion to be used by the organization’s Policy Committee in awarding biannual bonuses. Literature related to corporate peer reviews as well as the use of groupware provided the basis for questions posed. Both nondirective and focused interviews were conducted with key players and a sampling of actual evaluation data was collected. Analysis indicated that perceived management (noncommitment to using peer review data and issues of confidentiality may have led many individuals to be skeptical about the value of a peer review. As to the use of groupware to enable the evaluation, users were quite pleased; however, planners’ initial resistance to using this technology was evident and early efforts to devise usable reports were troublesome.

  20. New Aspects in the Formulation of Drugs Based on Three Case Studies.

    Science.gov (United States)

    Frohberg, Patrick; Nguyen, Thi Nhat Phuong; Ulrich, Joachim

    2016-01-01

    The improvement of pharmaceutical dosage forms, such as tablets, towards drug delivery control and cost efficiency is of great importance in formulation technologies. Here, three examples: in situ coating, freeze casting and protein-based biocomposites are presented that address the above mentioned issues and contribute to further developments in formulation technologies. The in situ coating increases the economic efficiency by saving process steps in comparison to a conventional tableting process and provides a crystalline coating for a tailorable drug delivery rate. The freeze casting allows the control over the surface area of a drug delivery system (DDS) by providing different numbers and sizes of pores, which in conjunction with adequate additives offer an efficient instrument for drug delivery control, especially by accelerating the dissolution effect. Protein-based biocomposites are attractive materials for biomedical and pharmaceutical applications that can be applied as a polymeric DDS. They inherently combine degradability in vivo and in vitro, show a good biocompatibility, offer sites of adhesion for cells and may additionally be used to release embedded bioactive molecules. Here, a new approach regarding the incorporation of crystalline active pharmaceutical ingredients (API) into a protein matrix in one process step is presented. All three presented techniques mark decisive progress towards tailor-made drug delivery systems with respect to function, economic efficiency and the generation of additional values. PMID:27144546

  1. Smoking, environmental tobacco smoke, and risk of renal cell cancer: a population-based case-control study

    Directory of Open Access Journals (Sweden)

    Siddiqui Tariq

    2008-12-01

    Full Text Available Abstract Background Kidney and renal pelvis cancers account for 4% of all new cancer cases in the United States, among which 85% are renal cell carcinomas (RCC. While cigarette smoking is an established risk factor for RCC, little is known about the contribution of environmental tobacco smoke (ETS to RCC incidence. This study assesses the role of smoking and ETS on RCC incidence using a population-based case-control design in Florida and Georgia. Methods Incident cases (n = 335 were identified from hospital records and the Florida cancer registry, and population controls (n = 337 frequency-matched by age (+/- 5 years, gender, and race were identified through random-digit dialing. In-person interviews assessed smoking history and lifetime exposure to ETS at home, work, and public spaces. Home ETS was measured in both years and hours of exposure. Odds ratios and 95% confidence intervals were calculated using logistic regression, controlled for age, gender, race, and BMI. Results Cases were more likely to have smoked 20 or more pack-years, compared with never-smokers (OR: 1.35, 95% CI: 0.93 – 1.95. A protective effect was found for smoking cessation, beginning with 11–20 years of cessation (OR: 0.39, 95% CI: 0.18–0.85 and ending with 51 or more years of cessation (OR: 0.11, 95% CI: 0.03–0.39 in comparison with those having quit for 1–10 years. Among never-smokers, cases were more likely to report home ETS exposure of greater than 20 years, compared with those never exposed to home ETS (OR: 2.18; 95% CI: 1.14–4.18. Home ETS associations were comparable when measured in lifetime hours of exposure, with cases more likely to report 30,000 or more hours of home ETS exposure (OR: 2.37; 95% CI: 1.20–4.69. Highest quartiles of combined home/work ETS exposure among never-smokers, especially with public ETS exposure, increased RCC risk by 2 to 4 times. Conclusion These findings confirm known associations between smoking and RCC and establish a

  2. Methylenetetrahydrofolate reductase gene A1298C polymorphism in pediatric stroke--case-control and family-based study.

    Science.gov (United States)

    Balcerzyk, Anna; Niemiec, Paweł; Kopyta, Ilona; Emich-Widera, Ewa; Pilarska, Ewa; Pienczk-Ręcławowicz, Karolina; Kaciński, Marek; Wendorff, Janusz; Żak, Iwona

    2015-01-01

    Moderate hyperhomocysteinemia is one of the risk factors of pediatric stroke. Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme, which regulates homocysteine metabolism, and some polymorphisms of gene encoding this enzyme are associated with a decreased activity of the enzyme. The aim of the study was to assess an association between the A1298C polymorphism and pediatric stroke. We also evaluated a possible synergistic effect of A1298C and C677T polymorphisms of this gene. The study group consisted of 88 children after ischemic stroke, 142 of their parents and 111 controls. The A1298C polymorphism was genotyped using the restriction fragment length polymorphism method. We used 2 study designs: a case-control model and a family-based association test. The Statistica 7.1 and EpiInfo 6 softwares were used in all analyses. We did not observe any statistically significant differences either in the transmission of the A allele in the family-based test or in the frequency of the A allele in the patients group compared with the controls. We also did not notice any significant additive or synergistic effects between the A1298C and C677T polymorphisms. An analysis of the results obtained in this study and a critical review of previously published studies indicate that the A1298C polymorphism of the MTHFR gene is not related to ischemic stroke in children. PMID:25440348

  3. Exploring Coaching Actions Based on Developed Values: A Case Study of a Female Hockey Coach

    Science.gov (United States)

    Callary, Bettina; Werthner, Penny; Trudel, Pierre

    2013-01-01

    There are few empirical studies that demonstrate how values are developed and how they are linked to coaching actions. There can be a discrepancy between the statement of coaches' values and their actual coaching actions. In order to examine how coaching actions are influenced by values that are developed over a lifetime, the purpose of this…

  4. Fostering Digital Literacy through Web-Based Collaborative Inquiry Learning--A Case Study

    Science.gov (United States)

    Jun, Fu; Pow, Jacky

    2011-01-01

    Digital literacy (DL), a term that emerged with the explosion of digital information and multimedia technology, refers to basic competence in using digital technology. The present study first analyzed the evolvement from media literacy to digital literacy and developed a four-branch theoretical framework of DL by investigating related definitions…

  5. A Process-Based Knowledge Management System for Schools: A Case Study in Taiwan

    Science.gov (United States)

    Lee, Chi-Lung; Lu, Hsi-Peng; Yang, Chyan; Hou, Huei-Tse

    2010-01-01

    Knowledge management systems, or KMSs, have been widely adopted in business organizations, yet little research exists on the actual integration of the knowledge management model and the application of KMSs in secondary schools. In the present study, the common difficulties and limitations regarding the implementation of knowledge management into…

  6. Clearing the Highest Hurdle: Human-Based Case Studies Broaden Students' Knowledge of Core Evolutionary Concepts

    Science.gov (United States)

    Werth, Alexander J.

    2009-01-01

    An anonymous survey instrument was used for a ten year study to gauge college student attitudes toward evolution. Results indicate that students are most likely to accept evolution as a historical process for change in physical features of non-human organisms. They are less likely to accept evolution as an ongoing process that shapes all traits…

  7. Problem-Based Educational Environments: A Case Study in e-Commerce and Business Planning

    Science.gov (United States)

    Megalakaki, Olga; Sotiriou, Sofoklis; Savas, Stavros; Manoussakis, Yannis

    2012-01-01

    Introduction: The purpose of the present study was to explore the educational and cognitive aspects of an innovative approach to Internet use within an interdisciplinary, integrated framework for activities set up to enable students to acquire knowledge informally. These activities had the potential to provide real-world results through a model…

  8. Syntactic and Semantic Coordination in Finite Complement-Clause Constructions: A Diary-Based Case Study

    Science.gov (United States)

    Köymen, Bahar; Lieven, Elena; Brandt, Silke

    2016-01-01

    This study investigates the coordination of matrix and subordinate clauses within finite complement-clause constructions. The data come from diary and audio recordings which include the utterances produced by an American English-speaking child, L, between the ages 1;08 and 3;05. We extracted all the finite complement-clause constructions that L…

  9. Implementation of Link-based DMS Supporting ISO 9001 QMS: Case Study

    Directory of Open Access Journals (Sweden)

    Marek Kacmar

    2013-12-01

    Full Text Available Document Management System supporting ISO 9001 Quality Management System is a typical application of Document Management it the enterprise environment. In order to be effective and sustainable it has to be implemented by taking into consideration organization’s own environment and culture. The article reviwes the ISO 9001 requirements on Document Management and available articles dealing with implementation of DMS. It uses a proposed methodology for the implementation of DMS supporting ISO 9001 on the real life example of an enterprise organization. Resulting link-based DMS suports the management of documents from various document storage systems and enable users to use either original sources or to access a central list of all documents.

  10. Developing an Interventional Pulmonary Service in a Community-Based Private Practice: A Case Study.

    Science.gov (United States)

    French, Kim D; Desai, Neeraj R; Diamond, Edward; Kovitz, Kevin L

    2016-04-01

    Interventional pulmonology (IP) is a field that uses minimally invasive techniques to diagnose, treat, and palliate advanced lung disease. Technology, formal training, and reimbursement for IP procedures have been slow to catch up with other interventional subspecialty areas. A byproduct of this pattern has been limited IP integration in private practice settings. We describe the key aspects and programmatic challenges of building an IP program in a community-based setting. A philosophical and financial buy-in by stakeholders and a regionalization of services, within and external to a larger practice, are crucial to success. Our experience demonstrates that a successful launch of an IP program increases overall visits as well as procedural volume without cannibalizing existing practice volume. We hope this might encourage others to provide this valuable service to their own communities. PMID:26836941

  11. Zero-base budgeting in the federal government: a case study.

    Science.gov (United States)

    Herzlinger, R E

    1979-01-01

    The implementation of a zero-base budgeting system in Federal government agencies, instituted by President Carter in 1977, yielded quite different results, not only among the agencies but within specific departments as well. The experience of the Public Health Service with this budgeting process is documented and analyzed in this article. Though the individual PHS agencies generally felt that ZBB is a poor budgetary tool, the author's principal claims are that the technique was misused and that its application may well be inappropriate for the entire budget of a large political system. The result, according to Professor Herzlinger, was that those individuals who should have been the prime beneficiaries of the ZBB process were most disappointed by it. PMID:10240700

  12. Comprehensive techno-economic analysis of wastewater-based algal biofuel production: A case study.

    Science.gov (United States)

    Xin, Chunhua; Addy, Min M; Zhao, Jinyu; Cheng, Yanling; Cheng, Sibo; Mu, Dongyan; Liu, Yuhuan; Ding, Rijia; Chen, Paul; Ruan, Roger

    2016-07-01

    Combining algae cultivation and wastewater treatment for biofuel production is considered the feasible way for resource utilization. An updated comprehensive techno-economic analysis method that integrates resources availability into techno-economic analysis was employed to evaluate the wastewater-based algal biofuel production with the consideration of wastewater treatment improvement, greenhouse gases emissions, biofuel production costs, and coproduct utilization. An innovative approach consisting of microalgae cultivation on centrate wastewater, microalgae harvest through flocculation, solar drying of biomass, pyrolysis of biomass to bio-oil, and utilization of co-products, was analyzed and shown to yield profound positive results in comparison with others. The estimated break even selling price of biofuel ($2.23/gallon) is very close to the acceptable level. The approach would have better overall benefits and the internal rate of return would increase up to 18.7% if three critical components, namely cultivation, harvest, and downstream conversion could achieve breakthroughs. PMID:27039331

  13. Evidence-based medicine – an appropriate tool for evidence-based health policy? A case study from Norway

    OpenAIRE

    Malterud, Kirsti; Bjelland, Anne Karen; Elvbakken, Kari Tove

    2016-01-01

    Abstract Background Evidence-based policy (EBP), a concept modelled on the principles of evidence-based medicine (EBM), is widely used in different areas of policymaking. Systematic reviews (SRs) with meta-analyses gradually became the methods of choice for synthesizing research evidence about interventions and judgements about quality of evidence and strength of recommendations. Critics have argued that the relation between research evi...

  14. Rotordynamic Stability Case Studies

    OpenAIRE

    Choudhury Pranabesh

    2004-01-01

    In this article case studies are presented involving rotordynamic instability of modern high-speed turbomachinery relating the field data to analytical methods. The studies include oil seal related field problems, instability caused by aerodynamic cross-coupling in high-pressure, high-speed compressors, and hydrodynamic bearing instability resulting in subsynchronous vibration of a high-speed turbocharger. It has been shown that the analytical tools not only help in problem diagnostics, bu...

  15. Prague Case Study Report

    Czech Academy of Sciences Publication Activity Database

    Kostelecký, Tomáš; Patočková, Věra; Illner, Michal; Vobecká, Jana; Čermák, Daniel

    Aarau: Centre for Democracy Studies Aarau (ZDA), 2014 - (Widmer, C.; Kübler, D.), s. 131-177 ISBN 978-3-9524228-2-3 R&D Projects: GA AV ČR IAA700280802 Institutional support: RVO:68378025 Keywords : urban neighbourhods * regeneration * Prague Subject RIV: AD - Politology ; Political Sciences http://www.zdaarau.ch/dokumente/en/ZDA_Working-Papers/No3_RUN_case-studies_2014.pdf

  16. Driver Sleepiness and Risk of Car Crashes in Shenyang, a Chinese Northeastern City: Population-based Case-control Study

    Institute of Scientific and Technical Information of China (English)

    GAI-FEN LIU; SONG HAN; DUO-HONG LIANG; FENG-ZHI WANG; XIN-ZHU SHI; JIAN YU; ZHENG-LAI WU

    2003-01-01

    To estimate the association of driver sleepiness with the risk of car crashes.Methods A population-based case-control study was conducted in Shenyang, a northeastern city in China, between November 2001 and July 2002. The case group comprised 406 car drivers involved in crashes, and 438 car drivers recruited at randomly selected sites, and on the day of week, and the time of day when they were driving on highways in the study region during the study period were used as control groups. Face-to-face interviews with drivers were conducted according to a well-structured questionnaire covering the circumstances of their current trip and their background information.Stanford sleepiness scale and Epworth sleepiness scale were used to quantify acute sleepiness and chronic sleepiness respectively. Results There was a strong association between chronic sleepiness and the risk of car crash. Significantly increased risk of crash was associated with drivers who identified themselves as sleepy (Epworth sleepiness score ≥ 10 vs <10; adjusted odds ratio 2.07, 95%confidence interval 1.30 to 3.29), but no increased risk was associated with measures of acute sleepiness. Conclusions Chronic sleepiness in car drivers significantly increases the risk of car crash. Reductions in road traffic injuries may be achieved if fewer people drive when they are sleepy.

  17. Risk factors for hospitalization due to community-acquired sepsis - a population-based case-control study

    DEFF Research Database (Denmark)

    Henriksen, Daniel Pilsgaard; Pottegård, Anton; Laursen, Christian B;

    2015-01-01

    BACKGROUND: The aim of the study was to estimate risk factors for hospitalization due to sepsis and to determine whether these risk factors vary by age and gender. METHODS: We performed a population-based case-control study of all adult patients admitted to a medical ED from September 2010.......3%) were male. 621 (36.3%) patients were admitted with sepsis, 1071 (62.5%) with severe sepsis and 21 (1.2%) with septic shock. Episodes with sepsis of any severity were associated with older age (85+ years adjusted OR 6.02 [95%CI: 5.09-7.12]), immunosuppression (4.41 [3.83-5.09]), alcoholism...

  18. The evolution of network-based business models illustrated through the case study of an entrepreneurship project

    DEFF Research Database (Denmark)

    Lund, Morten; Nielsen, Christian

    2014-01-01

    implications: Managers can gain insight into barriers and enablers relating to different types of loose organisations and how to best manage such relationships and interactions Originality/value: This study adds value to the existing literature by reflecting the dynamics created in the interactions between a...... time and how the role of strategic partners may differ over time too. Design/methodology/approach: A longitudinal case study spanning over years and mobilising multiple qualitative methods such as interviews, observation and participative observation forms the basis of the data collection. Findings......: This paper illustrates how a network-based business model arises and evolves and how the forces of a network structure impact the development of its partner relationships. The contribution of this article is to understanding how partners positioned around a business model can be organized into a...

  19. A Cycle Model of Co-evolution between Emerging Technology and Firm’s Capabilities Based on Case Study

    Institute of Scientific and Technical Information of China (English)

    Wang; Min; Li; Limiao; Yin; Lu

    2011-01-01

    This study explores the mechanism on the co-evolution between emerging technology and capability.Our research focus is how the firms capabilities affect the evolution of emerging technology through strategy.Based on the theoretical analysis and case study,this paper builds a theoretical framework:firms capability is classified into static capability and dynamic capability,and the evolution of emerging technology is summarized by a cycle model.Further,strategy is looked as a mediated variable.The conclusion is that the static capability affects the emerging technology evolution through strategy implement,and the dynamic capability affects the evolution through strategy change.In both situations,organization learning is a key capability to the evolution of emerging technology.

  20. Discrimination Based on Health Grounds : Case Study: Hepatitis B Virus Discrimination in China Labour Employment

    OpenAIRE

    2006-01-01

    Nowadays, due to the high prevalence of hepatitis B in China, millions of carriers are faced with discrimination when they come to work, study, health care or even marriage. The same situation also happens to those physically disadvantageous people especially in the access to employment. Employment discrimination detracts from the principle of equality and directly impairs social justice and human dignity. Series of institutional responses are needed to effectively prevent employment discrimi...

  1. Construction waste management based on industrial management models: a Swedish case study

    OpenAIRE

    Stenis, Jan

    2005-01-01

    This paper describes a methodology for estimating the true internal costs of construction waste, aimed at promoting environmentally friendly waste management. The study employs cost-benefit analysis, contribution margin analysis, the polluter-pays principle and a mathematical model: the model for Efficient Use of Resources for Optimal Production Economy (EUROPE), which has been introduced previously by the author for assigning industrial costs to waste. The calculations are performed on const...

  2. Female Sexual Victimization Predicts Psychosis: A Case-Control Study Based on the Danish Registry System

    DEFF Research Database (Denmark)

    Elklit, A.; Shevlin, Mark

    2011-01-01

    the dependent variable was a postindex year diagnosis of psychosis. The OR associated with sexual victimization (OR = 10.04; 95% CI 2.50-40.33) indicted an increased likelihood of psychosis while controlling for the other predictors in the model. Conclusions: This study found that sexual victimization...... significantly increased the likelihood of a diagnosis of psychosis and therefore suggests that there may be a role for traumatic experiences in the etiology of psychosis....

  3. Modeling Landfill Suitability Based on GIS and Multicriteria Decision Analysis: Case Study in Al-Mahaweelqadaa

    OpenAIRE

    Mohammad Ali Alanbari; Nadhir Al-Ansari; Hadeel Kareem Jasim; Sven Knutsson

    2014-01-01

    Waste management system is not regulated in Iraq. At present, there are various techniques used for solid waste management such as landfill, thermal treatment, biological treatment, recycling etc. Landfill is the most common mode for the disposal of solid waste. However, landfill site selection is a quite complex process and it depends on several criteria and regulations. In this study landfill site selection is performed for Al-Mahaweelqadaa using Multicriteria Decisio...

  4. Pragmatism and Community Inquiry: A Case Study of Community-Based Learning

    OpenAIRE

    Bruce, Bertram C.; Bloch, Naomi

    2013-01-01

    This paper develops a philosophical basis for the concept of community inquiry. Community inquiry derives from pragmatist theory as articulated by Dewey, Peirce, Addams, and others. Following Brendel, we discuss pragmatism in terms of its emphasis on the practical dimensions of inquiry, the pluralistic nature of the tools that are used to study phenomena, the participatory role of individuals with different perspectives, and the provisional nature of inquiry. We then apply this framework in a...

  5. A Conservation-Based Approach to Compensation for Livestock Depredation: The Florida Panther Case Study

    OpenAIRE

    Caitlin E Jacobs; Main, Martin B.

    2015-01-01

    Calf (Bos taurus) depredation by the federally endangered Florida panther (Puma concolor coryi) on ranches in southwest Florida is an important issue because ranches represent mixed landscapes that provide habitat critical to panther recovery. The objectives of this study were to (1) quantify calf depredation by panthers on two ranches in southwest Florida, and (2) develop a habitat suitability model to evaluate the quality of panther hunting habitat on ranchlands, assess whether the model co...

  6. Terrain-based mapping of landslide susceptibility using a geographical information system: A case study

    OpenAIRE

    Lee, CF; Dai, FC

    2001-01-01

    This paper deals with the development of a technique for mapping landslide susceptibility using a geographical information system (GIS), with particular reference to landslides on natural terrain. The method has been applied to Lantau Island, the largest outlying island within the territory of Hong Kong. Landslide susceptibility in the study area is related to a number of terrain variables, viz., lithology, slope gradient, slope aspect, elevation, land cover, and distance to drainage line. Mu...

  7. GIS-based landscape design research: Stourhead landscape garden as a case study

    OpenAIRE

    Nijhuis, S.

    2015-01-01

    Landscape design research is important for cultivating spatial intelligence in landscape architecture. This study explores GIS (geographic information systems) as a tool for landscape design research – investigating landscape designs to understand them as architectonic compositions and to acquire design knowledge that can be used in the creation and refinement of a design. The research aims to identify and illustrate the potential role of GIS as a tool in landscape design research, so as to p...

  8. Understanding the context of balanced scorecard implementation: a hospital-based case study in pakistan

    OpenAIRE

    Ajmal Agha; Jahan Firdous; Nabi Naheed; Razzak Junaid A; Jafri SM Wasim; Abbas Farhat; Lalji Sabrina NH; Rabbani Fauziah; Petzold Max; Brommels Mats; Tomson Goran

    2011-01-01

    Abstract Background As a response to a changing operating environment, healthcare administrators are implementing modern management tools in their organizations. The balanced scorecard (BSC) is considered a viable tool in high-income countries to improve hospital performance. The BSC has not been applied to hospital settings in low-income countries nor has the context for implementation been examined. This study explored contextual perspectives in relation to BSC implementation in a Pakistani...

  9. Mobilising community-based research on zoonotic infections: A case study of longitudinal cohorts in Vietnam

    OpenAIRE

    Karen Saylors; Tue Ngo Tri; Toan Tran Khanh; Kiet Bach Tuan; Heiman FL Wertheim; Stephen Baker; Hoa Ngo Thi; Bryant, Juliet E

    2015-01-01

    We initiated the Vietnam Initiative on Zoonotic Infections (VIZIONS) research program to better understand the epidemiology of disease transmission at the human–animal interface in Vietnamese rural communities and to integrate One Health approaches to disease surveillance. We established a longitudinal community cohort study of individuals with occupational exposure to animals, which involves concurrent targeted sampling from domestic livestock species and follow-up monitoring of human clinic...

  10. Case Study Report: Community-Based Monitoring Systems for REDD+ in Guyana

    Directory of Open Access Journals (Sweden)

    Helen Bellfield

    2015-01-01

    Full Text Available A fundamental component of initiatives to reduce emissions from deforestation and forest degradation (REDD+; will be the development of robust and cost-effective measuring, reporting, and verification (MRV instruments for national forest monitoring and safeguard information systems. It is increasingly recognized that community-based monitoring (CBM offers a positive model for greater participation and engagement of indigenous and forest-dependent communities within a REDD+ framework. Yet plans for CBM within REDD+ MRV systems remain limited, and there are currently relatively few concrete examples of CBM informing national forest monitoring systems. This paper outlines findings from a community MRV project with Amerindian communities in the North Rupununi, Guyana; and demonstrates that a CBM approach can enable key REDD+ requirements: in understanding local deforestation drivers and measuring carbon stocks; and for providing information on safeguards through social and environmental assessments. In addition, the authors discuss community capacity-building on smartphone technology for monitoring as a challenging yet viable pathway for scaling the use and adoption of indigenous knowledge and local skills for REDD+ programs.

  11. A Case Study on Developing an Effective Information Based Healthcare Services - India's Scenario

    Directory of Open Access Journals (Sweden)

    A. Pathanjali Sastri

    2013-02-01

    Full Text Available The real test of technological development is to ensure whether it reaches people and the most important task is to produce, manage and deliver relevant information systems appropriately within India. Therefore technology needs to be acquired and adapted for it to be appropriately developed. A country like India needs to adapt and develop information systems based on their own needs and structures, using their own methods and practices. When it comes to eGovernance projects, better cooperation is the need of the day both from public as well as private players [1]. The Indian government is taking greater cognizance of the benefits of technology and some e-Gov projects have already been initiated and deployed in few states of our country [1]. However, despite an improved Information Communication Technology (ICT in our country thanks to the efforts of our government, there are still problems which continue to hamper the use of information and ICT in domain of healthcare in India [2]. This paper discusses the current levels of IT and quality in health care in our country and how Information Technology (IT might be helpful in future.

  12. Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study

    Directory of Open Access Journals (Sweden)

    Harris Christopher

    2009-03-01

    Full Text Available Abstract Background Structure-based drug design (SBDD can provide valuable guidance to drug discovery programs. Robust construct design and expression, protein purification and characterization, protein crystallization, and high-resolution diffraction are all needed for rapid, iterative inhibitor design. We describe here robust methods to support SBDD on an oral anti-cytokine drug target, human MAPKAP kinase 2 (MK2. Our goal was to obtain useful diffraction data with a large number of chemically diverse lead compounds. Although MK2 structures and structural methods have been reported previously, reproducibility was low and improved methods were needed. Results Our construct design strategy had four tactics: N- and C-terminal variations; entropy-reducing surface mutations; activation loop deletions; and pseudoactivation mutations. Generic, high-throughput methods for cloning and expression were coupled with automated liquid dispensing for the rapid testing of crystallization conditions with minimal sample requirements. Initial results led to development of a novel, customized robotic crystallization screen that yielded MK2/inhibitor complex crystals under many conditions in seven crystal forms. In all, 44 MK2 constructs were generated, ~500 crystals were tested for diffraction, and ~30 structures were determined, delivering high-impact structural data to support our MK2 drug design effort. Conclusion Key lessons included setting reasonable criteria for construct performance and prioritization, a willingness to design and use customized crystallization screens, and, crucially, initiation of high-throughput construct exploration very early in the drug discovery process.

  13. Semantics-Based Intelligent Indexing and Retrieval of Digital Images - A Case Study

    Science.gov (United States)

    Osman, Taha; Thakker, Dhavalkumar; Schaefer, Gerald

    The proliferation of digital media has led to a huge interest in classifying and indexing media objects for generic search and usage. In particular, we are witnessing colossal growth in digital image repositories that are difficult to navigate using free-text search mechanisms, which often return inaccurate matches as they typically rely on statistical analysis of query keyword recurrence in the image annotation or surrounding text. In this chapter we present a semantically enabled image annotation and retrieval engine that is designed to satisfy the requirements of commercial image collections market in terms of both accuracy and efficiency of the retrieval process. Our search engine relies on methodically structured ontologies for image annotation, thus allowing for more intelligent reasoning about the image content and subsequently obtaining a more accurate set of results and a richer set of alternatives matchmaking the original query. We also show how our well-analysed and designed domain ontology contributes to the implicit expansion of user queries as well as presenting our initial thoughts on exploiting lexical databases for explicit semantic-based query expansion.

  14. Fractal Determination of Coastal Types Based on GIS--A Case Study of China

    Institute of Scientific and Technical Information of China (English)

    Zhu Xiaohua; Wu Xiuqin; Wang Jian

    2002-01-01

    The probability of fractal determination of coastal types based on GIS is preliminarily discussed with China as an example. Finally, some significant conclusions are drawn: (1) The fractal dimension of coastline of the bedrock coast is larger than that of the plain coast on the same scale map; (2) As far as the bedrock coast is concerned, the larger fractal dimension of coastline of the bedrock coast on the same scale map indicates that the bedrock coast is probably not typical; (3) As far as the plain coast is concerned, the smaller fractal dimension of coastline of the plain coast on the same scale map indicates that it is probably the silt plain coast; (4) The different substantial compositions affect the fractal dimensions of coastlines of different coastal types. In general, the coast which lies in the north of the Hangzhou Bay consists of sand mainly, its surface is flat, and it is connected with the coastal plain, its landform is broad shoal, its total change is comparatively homogenous in the tidal dynamic process, and thus, the relatively smaller fractal dimension of coastline results from this. For the bedrock coast, there is more bedrock, the coastline is comparatively smooth and straight, being affected by the faults and ocean dynamic process, which result in the larger fractal dimension.

  15. A Carbon Exergy Tax Evaluation Based on the Efficient Use of Energy Resources: A Case Study

    Directory of Open Access Journals (Sweden)

    Massimo Santarelli

    2000-09-01

    Full Text Available

    An instrument to promote the CO2 emission reductions, taking the Kyoto Protocol goal into account, can be the assignment to energy conversion plants of a monetary charge linked to their specific emission intensity. Once the choice of a charge is defined, the next problem is the choice of a strategy to determine the amount of the imposed charge, named Carbon Tax (CT.

    In this paper an analytical procedure for the Carbon Tax evaluation is proposed and applied. This approach is based on the concept of Efficiency Penalty of the energy system, that represents the evaluation of the cost of the exergy destroyed inside the system and the cost of the exergy rejected in the biosphere with the plant wastes; the Efficiency Penalty term is coupled with the evaluation of the Index of CO2 Emission, which connects the amount of the CO2 emitted by the plant with the Second Law efficiency of the plant itself. The evaluated charge on the CO2 emissions is defined as Carbon Exergy Tax (CET. The procedure is applied here to the analysis of a 700 MW combined plant burning fossil fuels in two different configurations: a typical natural gas fired combined plant, and a coal fired combined plant burning coal in a Pressurised Fluidised Bed Combustor (PFBC.

  16. Design of a Hospital-Based Database System (A Case Study of BIRDEM

    Directory of Open Access Journals (Sweden)

    Rosina Surovi Khan,

    2010-11-01

    Full Text Available As technology advances, information in different organizations of Bangladesh can no more be maintained manually. There is a growing need for the information to become computerized so that it can be suitably stored. This is where databases come into the picture. Databases are convenient storage systems which can store large amounts of data and together with application programs such as interfaces they can aid in faster retrieval of data. An initiative was taken to design a complete database system for a hospital management such as Bangladesh Institute of Research and rehabilitation in Diabetes, Endocrine and Metabolic disorders (BIRDEM in Dhaka so that its information can be stored, maintained, updated and retrieved conveniently and efficiently. The existing information in BIRDEM is partly computerized via databases only in patients’ admissions, doctors’ appointments and medical tests and reports sections. A partly slow and tedious manual system still exists in BIRDEM for example, in record of ambulances in service,assigning ward boys and nurses to rooms, the billing process andrecord of doctors’ prescriptions etc. However, this paper outlinesone complete database design for the entire BIRDEM hospital inwhich data maintenance and retrieval are in perfect harmony and speedy. Sample SQL-based queries executed on the designed system are also demonstrated.

  17. Hypersomnia in children affected by migraine without aura: a questionnaire-based case-control study

    Directory of Open Access Journals (Sweden)

    Esposito M

    2013-02-01

    Full Text Available Maria Esposito,1 Michele Roccella,2 Lucia Parisi,2 Beatrice Gallai,3 Marco Carotenuto11Center for Childhood Headache, Unit of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical, and Preventive Medicine, Second University of Naples, Naples, Italy; 2Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, ItalyBackground: The relationship between sleep and headache is meaningful and complex. Children affected by migraines tend to show many sleep disorders, such as insufficient sleep duration and excessive daytime somnolence. Therefore, the aim of this study is to assess the rate of reported sleep habits and self-reported sleepiness in a large pediatric sample of individuals affected by migraine without aura (MoA.Methods: The study population consisted of 271 children aged between 6 and 13 years affected by MoA. The control group was composed of 305 typically developing children. To assess the sleep habits of all individuals (MoA and control, parents filled out the Sleep Disturbance Scale for Children, and to check the degree of subjective perceived daytime sleepiness, all subjects were administered the Pediatric Daytime Sleepiness Scale.Results: The two study groups were matched for age (P = 0.124, sex distribution (P = 0.775, and body mass index z-score (P = 0.107. Parents of children affected by MoA reported a higher total score of sleep disorder symptoms (P < 0.001, disorders of initiating and maintaining (P < 0.001, and disorders of arousal (P < 0.001 than did parents of controls. No significant differences were found in disorders of excessive somnolence. Conversely, in the Pediatric Daytime Sleepiness Scale, migraine children had higher scores (24.67 ± 3.19 vs 11.94 ± 4.81; P < 0.001 and a reduction in referred total sleep time mean duration (469.83 ± 98.112 vs 527.94 ± 83.02; P < 0.001 than typically

  18. A case study on the urban impervious surface distribution based on a BCI index

    Science.gov (United States)

    Chen, Xiaolin; Sun, Genyun; Wang, Zhenjie

    2015-12-01

    Endmember selection is the key to success in pixel unmixing which plays an important role in urban impervious surface abundance extraction. During the extraction, however, there has been a problem for the discrimination of impervious surfaces and soils because of their similarity in spectral. This increase the difficulty in distinguishes impervious surface and soil in endmember selection. To address this issue, in the current study, the biophysical composition index (BCI) and soil adjusted vegetation index (SAVI) were introduced to enhance the information of impervious surface and bare soil in the study area. Then, by selecting high albedo, low albedo, soil and vegetation endmembers with the utilization of the histogram of the indices and minimum noise fraction (MNF) scatter plot, we applied spectral mixture analysis (SMA) to extract impervious surface abundance. The scene of multispectral Landsat TM image was acquired allowing for the interpretation and analysis of impervious surfaces distribution. Experiments and comparisons indicate that this method performs well in estimating subpixel impervious surface distribution with relatively high precision and small bias.

  19. Community-Based Coastal Resource Management (CB-CRM: a Case Study f Mariveles, Bataan, Philippines

    Directory of Open Access Journals (Sweden)

    Andrew Lou L. Mungcal

    2013-11-01

    Full Text Available This paper addressed the issue of sustainable coastal resource management through a successful Community-Based Coastal Resource Management (CB-CRM Program in the Municipality of Mariveles, province of Bataan in the Philippines. The paper investigated how governance and institutional and legislative framework, and the concept of sustainable development complemented each other to promote good local eco-governance in the management and protection of finite local marine resources. Specifically, it analyzed how the local fisherfolk community of Mariveles utilized efficiently their finite marine resources in the context of eco-governance. It also investigated how the cooperative efforts of various stakeholders: peoples’ organizations (POs, local government unit (LGU, and a non-government organization (NGO in Mariveles, Bataan affected their coastal resources against environmental degradation and exploitation. This paper would benefit POs, LGUs, and NGOs in their quest for sustainable management and conservation of their limited coastal resources. This paper yielded the following findings. First, POs and NGOs engage when NGOs can strengthen the POs’ capacity building through the transfer of skills and technology, when NGOs can enhance the POs’ indigenous knowledge, and when NGOs are more knowledgeable of formal venues of LGU participation. Second, LGUs, NGOs and POs engage when POs and NGOs can complement each other to strengthen their capacity building, and when NGOs can help implement environmental programs that are beneficial to the POs. Third, NGOs and POs engage when POs are threatened by elite power, and when NGOs want their environmental issues on LGU’s legislative agenda. Finally, NGOs and POs engage when they see possible LGU cooperation. Participant observation through focus group discussion (FGD and key informants’ interview of different stakeholders was a primary source of information in formulating the aforementioned conclusions

  20. The reflexive case study method

    DEFF Research Database (Denmark)

    Rittenhofer, Iris

    2015-01-01

    This paper extends the international business research on small to medium-sized enterprises (SME) at the nexus of globalization. Based on a conceptual synthesis across disciplines and theoretical perspectives, it offers management research a reflexive method for case study research of postnational...

  1. Cognitive training transfer using a personal computer-based game: A close quarters battle case study

    Science.gov (United States)

    Woodman, Michael D.

    In this dissertation, liquid crystal (LC) materials and devices are investigated in order to meet the challenges for photonics and displays applications. We have studied three kinds of liquid crystal materials: positive dielectric anisotropic LCs, negative dielectric anisotropic LCs, and dual-frequency LCs. For the positive dielectric anisotropic LCs, we have developed some high birefringence isothiocyanato tolane LC compounds with birefringence ˜0.4, and super high birefringence isothiocyanato biphenyl-bistolane LC compounds with birefringence as high as ˜0.7. Moreover, we have studied the photostability of several high birefringence LC compounds, mixtures, and LC alignment layers in order to determine the failure mechanism concerning the lifetime of LC devices. Although cyano and isothiocyanato LC compounds have similar absorption peaks, the isothiocyanato compounds are more stable than their cyano counterparts under the same illumination conditions. This ultraviolet-durable performance of isothiocyanato compounds originates from its molecular structure and the delocalized electron distribution. We have investigated the alignment performance of negative dielectric anisotropic LCs in homeotropic (vertical aligned, VA) LC cell. Some (2, 3) laterally difluorinated biphenyls, terphenyls and tolanes are selected for this study. Due to the strong repulsive force between LCs and alignment layer, (2,3) laterally difluorinated terphenyls and tolanes do not align well in a VA cell resulting in a poor contrast ratio for the LC panel. We have developed a novel method to suppress the light leakage at dark state. By doping positive Deltaepsilon or non-polar LC compounds or mixtures into the host negative LC mixtures, the repulsive force is reduced and the cell exhibits an excellent dark state. In addition, these dopants increase the birefringence and reduce the viscosity of the host LCs which leads to a faster response time. In this dissertation, we investigate the

  2. CT ASSESSMENT OF BRAIN VENTRICULAR SIZE BASED ON AGE AND SEX: A STUDY OF 112 CASES

    Directory of Open Access Journals (Sweden)

    Vinoo

    2013-12-01

    Full Text Available CT being the primary modality of choice in many centers for the diagnosis of brain pathology, normal brain ventricular size measurem ents is an important parameter for the diagnosis of conditions like hydrocephalus, age related atrophic changes and also other brain pathologies producing ventriculomegaly. It is also important for knowing the normal upper and lower limits of the brain ven tricular system in the different age groups, and in both sexes so as to diagnose brain pathology.The ventricular system of the brain undergoes changes with aging and varies with gender.Our study consists of 48 female, and 64 male patients. Apart from the v entricular measurements, two ratios and two indices were also calculated – which included the right and left Evan’s ratio, CM index, and ventricular size inde

  3. APPLICATION OF PROJECT BASED LEARNING IN THE DISCIPLINE OF LOGISTICS: A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Paulo Cesar Chagas Rodrigues

    2011-06-01

    Full Text Available Currently the higher education institutions need to search for new tools and methods to make learning more enjoyable and dynamic for students because the job market increasingly needs young people who have the ability to self-criticism above average. A search was performed on a course of action and technologist who had a total of 15 students, for the purpose of this research was to improve the learning level of students, reducing absenteeism and dropout, encourage research and participation in teamwork. As a way to develop this study the students had to develop a project of a bridge made of newspaper and involving the disciplines of logistics, financial management, human resource management and managing projects.

  4. The case for launch of an international DNA based birth cohort study

    Directory of Open Access Journals (Sweden)

    Igor Rudan

    2011-06-01

    Full Text Available The global health agenda beyond 2015 will inevitably need to broaden its focus from mortality reduction to the social determinants of deaths, growing inequities among children and mothers, and ensuring the sustainability of the progress made against the infectious diseases. New research tools, including technologies that enable high-throughput genetic and ‘-omics’ research, could be deployed for better understanding of the aetiology of maternal and child health problems. The research needed to address those challenges will require conceptually different studies than those used in the past. It should be guided by stringent ethical frameworks related to the emerging collections of biological specimens and other health related information. We will aim to establish an international birth cohort which should assist low- and middle-income countries to use emerging genomic research technologies to address the main problems in maternal and child health, which are still major contributors to the burden of disease globally.

  5. Obstructive sleep apnea and the risk of atopic dermatitis: a population-based case control study.

    Directory of Open Access Journals (Sweden)

    Kai-Jen Tien

    Full Text Available BACKGROUND: Obstructive sleep apnea (OSA is associated with systemic inflammation and induces various comorbid medical diseases. To date, no study has explored the relationship between OSA and atopic dermatitis (AD, an inflammatory and autoimmune skin disorder. This study investigated the longitudinal risk for AD in patients with OSA. METHODS: A random sample of 1,000,000 individuals from Taiwan's National Health Insurance database was collected. From this sample, 1222 patients with newly-diagnosed OSA between 2000 and 2005 were identified and compared with a matched cohort of 18330 patients without OSA. All patients were tracked for 5.5 years from the index date in order to identify which patients subsequently developed AD. RESULTS: During the 5.5-year follow-up period, the incidence rates of AD in the OSA cohort and comparison groups were 9.81 and 6.21 per 1000 person-years, respectively. After adjustment for age, gender, diabetes, hypertension, coronary heart disease, obesity, allergy, allergic rhinitis, asthma, monthly income, and geographic location, patients with OSA were 1.5-times more likely to develop AD than patients without OSA (95% CI = 1.15-1.95, p = 0.0025. The hazard risk for AD was greater in male OSA patients and young OSA patients (0-18 and 19-34 years, adjusted HRs being 1.53 (95% CI = 1.14-2.06, p = 0.005, 4.01(95% CI = 1.57-10.26, p = 0.0038 and 1.75(95% CI = 1.00-3.04, p = 0.0483, respectively. The log-rank test indicated that OSA patients <35-years-old had significantly higher cumulative incidence rates of AD than those patient of the same age in the comparison group (p = 0.0001. CONCLUSION: Patients with OSA, especially male patients and younger patients, are at an increased risk for AD later in life.

  6. Using Case Studies To Teach Science.

    Science.gov (United States)

    Gabel, Connie

    Using case studies in science instruction develops problem solving and enhances listening and cooperative learning skills. Unlike other disciplines such as law and medicine, the case study method is rarely used in science education to enrich the curriculum. This study investigates the use of content-based case studies as a means of developing…

  7. Customized, Outcome-Based, Relevant Evaluation (CORE) at Lipscomb University: A Competency-Based Education Case Study

    Science.gov (United States)

    Klein-Collins, Rebecca; Olson, Rick

    2014-01-01

    In recent years, there has been a surge of interest in competency-based degree programs at the postsecondary level. These programs are promising for the future of higher education because they establish clear expectations for what graduates must know and be able to do, and many models have been designed to allow students to learn and earn a degree…

  8. Industrial Based Migration in India. A Case Study of Dumdum "Dunlop Industrial Zone"

    Science.gov (United States)

    Das, Biplab; Bandyopadhyay, Aditya; Sen, Jayashree

    2012-10-01

    Migration is a very important part in our present society. Basically Millions of people moved during the industrial revolution. Some simply moved from a village to a town in the hope of finding work whilst others moved from one country to another in search of a better way of life. The main reason for moving home during the 19th century was to find work. On one hand this involved migration from the countryside to the growing industrial cities, on the other it involved rates of migration, emigration, and the social changes that were drastically affecting factors such as marriage,birth and death rates. These social changes taking place as a result of capitalism had far ranging affects, such as lowering the average age of marriage and increasing the size of the average family.Migration was not just people moving out of the country, it also invloved a lot of people moving into Britain. In the 1840's Ireland suffered a terrible famine. Faced with a massive cost of feeding the starving population many local landowners paid for labourers to emigrate.There was a shift away from agriculturally based rural dwelling towards urban habitation to meet the mass demand for labour that new industry required. There became great regional differences in population levels and in the structure of their demography. This was due to rates of migration, emigration, and the social changes that were drastically affecting factors such as marriage, birth and death rates. These social changes taking place as a result of capitalism had far ranging affects, such as lowering the average age of marriage and increasing the size of the average family. There is n serious disagreement as to the extent of the population changes that occurred but one key question that always arouses debate is that of whether an expanding population resulted in economic growth or vice versa, i.e. was industrialization a catalyst for population growth? A clear answer is difficult to decipher as the two variables are so

  9. Supervised artificial neural network-based method for conversion of solar radiation data (case study: Algeria)

    Science.gov (United States)

    Laidi, Maamar; Hanini, Salah; Rezrazi, Ahmed; Yaiche, Mohamed Redha; El Hadj, Abdallah Abdallah; Chellali, Farouk

    2016-01-01

    In this study, a backpropagation artificial neural network (BP-ANN) model is used as an alternative approach to predict solar radiation on tilted surfaces (SRT) using a number of variables involved in physical process. These variables are namely the latitude of the site, mean temperature and relative humidity, Linke turbidity factor and Angstrom coefficient, extraterrestrial solar radiation, solar radiation data measured on horizontal surfaces (SRH), and solar zenith angle. Experimental solar radiation data from 13 stations spread all over Algeria around the year (2004) were used for training/validation and testing the artificial neural networks (ANNs), and one station was used to make the interpolation of the designed ANN. The ANN model was trained, validated, and tested using 60, 20, and 20 % of all data, respectively. The configuration 8-35-1 (8 inputs, 35 hidden, and 1 output neurons) presented an excellent agreement between the prediction and the experimental data during the test stage with determination coefficient of 0.99 and root meat squared error of 5.75 Wh/m2, considering a three-layer feedforward backpropagation neural network with Levenberg-Marquardt training algorithm, a hyperbolic tangent sigmoid and linear transfer function at the hidden and the output layer, respectively. This novel model could be used by researchers or scientists to design high-efficiency solar devices that are usually tilted at an optimum angle to increase the solar incident on the surface.

  10. Comparison based on environmental effects of nitrogen management techniques in a manure digestate case study.

    Science.gov (United States)

    Paccanelli, Nicola; Teli, Aronne; Scaglione, Davide; Insabato, Gabriele; Casula, Alessandro

    2015-01-01

    Due to climate issues and favourable energy market, biogas is spreading as a manure management technique. Digestate is rich in nutrient and has to be handled in order to respect the 'nitrate directive' that limits nitrogen field application in areas defined as vulnerable. In this study, we compared different nitrogen management scenarios: a non-treatment option, a biological short-cut nitrification, a complete autotrophic process (anammox) and ammonia stripping from membrane filtration concentrate. The environmental effect comparison was obtained with 'Cross media effects analysis' and life cycle assessment (LCA). The results were different in some aspects, especially the impacts on eutrophication. According to cross media, the best process is DENO 2, while LCA shows similar impacts for all techniques and the best solution would be the no-treatment option. The main reason to adopt a digestate treatment technique is the lack of area for a correct disposal. If LCA eutrophication results are multiplied with the hectares necessary for each technology, a result similar to that of cross media is obtained. PMID:26020425

  11. A reba-based analysis of packers workload: a case study

    Directory of Open Access Journals (Sweden)

    Andrzej M. Lasota

    2014-03-01

    Full Text Available Background: One of the elements of a logistics system is the subsystem of production, which is a system composed of physical elements such as machinery, tools and (most importantly people. In addition, system-dependent human operators are particularly prone to problems related to discomfort, which can affect production quality and increase training costs and absenteeism. The aim of this study was to assess the workload and risk of musculoskeletal discomfort (MSD's in the process of order fulfillment for the position of packer and to conduct an analysis of risk factors. Methods: The Rapid Entire Body Assessment (REBA evaluation method was used. Activities related to the fulfillment of an order were assessed for three workstations. Results: Five postures qualified for action category (AC 2, seven postures for AC 3 and one posture for AC 4. The main factors affecting the risk of a negative assessment of posture were keeping the back bent and twisted, keeping the arms raised above the trunk, working in a standing position and the weight of packaged carton. Conclusions: Packers working on research positions face a high level of exposure to the risk of MSD's, therefore corrective actions should be carried out as soon as possible. Ergonomic intervention should be linked to redesigning workstations and methods of working. After making changes to the research workstations, re-evaluation using the REBA method is recommended to verify the effectiveness of the changes.

  12. An improved formalism for quantum computation based on geometric algebra—case study: Grover's search algorithm

    Science.gov (United States)

    Chappell, James M.; Iqbal, Azhar; Lohe, M. A.; von Smekal, Lorenz; Abbott, Derek

    2013-04-01

    The Grover search algorithm is one of the two key algorithms in the field of quantum computing, and hence it is desirable to represent it in the simplest and most intuitive formalism possible. We show firstly, that Clifford's geometric algebra, provides a significantly simpler representation than the conventional bra-ket notation, and secondly, that the basis defined by the states of maximum and minimum weight in the Grover search space, allows a simple visualization of the Grover search analogous to the precession of a spin-{1/2} particle. Using this formalism we efficiently solve the exact search problem, as well as easily representing more general search situations. We do not claim the development of an improved algorithm, but show in a tutorial paper that geometric algebra provides extremely compact and elegant expressions with improved clarity for the Grover search algorithm. Being a key algorithm in quantum computing and one of the most studied, it forms an ideal basis for a tutorial on how to elucidate quantum operations in terms of geometric algebra—this is then of interest in extending the applicability of geometric algebra to more complicated problems in fields of quantum computing, quantum decision theory, and quantum information.

  13. Revegetation of extremely acid mine soils based on aided phytostabilization: A case study from southern China.

    Science.gov (United States)

    Yang, Sheng-Xiang; Liao, Bin; Yang, Zhi-Hui; Chai, Li-Yuan; Li, Jin-Tian

    2016-08-15

    Acidification is a major constraint for revegetation of sulphidic metal-contaminated soils, as exemplified by the limited literature reporting the successful phytostabilization of mine soils associated with pHacidification potential. In this study, a combination of ameliorants (lime and chicken manure) and five acid-tolerant plant species has been employed in order to establish a self-sustaining vegetation cover on an extremely acid (pHacidification potential. The results from the first two-year data showed that the addition of the amendments and the establishment of a plant cover were effective in preventing soil acidification. Net acid-generating potential of the mine soil decreased steadily, whilst pH and acid neutralization capacity increased over time. All the five acid-tolerant plants colonized successfully in the acidic metal-contaminated soil and developed a good vegetation cover within six months, and subsequent vegetation development enhanced organic matter accumulation and nutrient element status in the mine soil. The two-year remediation program performed on this extremely acid metalliferous soil indicated that aided phytostabilization can be a practical and effective restoration strategy for such extremely acid mine soils. PMID:27100018

  14. A case study of the carbon footprint of milk from high-performing confinement and grass-based dairy farms.

    Science.gov (United States)

    O'Brien, D; Capper, J L; Garnsworthy, P C; Grainger, C; Shalloo, L

    2014-03-01

    Life-cycle assessment (LCA) is the preferred methodology to assess carbon footprint per unit of milk. The objective of this case study was to apply an LCA method to compare carbon footprints of high-performance confinement and grass-based dairy farms. Physical performance data from research herds were used to quantify carbon footprints of a high-performance Irish grass-based dairy system and a top-performing United Kingdom (UK) confinement dairy system. For the US confinement dairy system, data from the top 5% of herds of a national database were used. Life-cycle assessment was applied using the same dairy farm greenhouse gas (GHG) model for all dairy systems. The model estimated all on- and off-farm GHG sources associated with dairy production until milk is sold from the farm in kilograms of carbon dioxide equivalents (CO2-eq) and allocated emissions between milk and meat. The carbon footprint of milk was calculated by expressing GHG emissions attributed to milk per tonne of energy-corrected milk (ECM). The comparison showed that when GHG emissions were only attributed to milk, the carbon footprint of milk from the Irish grass-based system (837 kg of CO2-eq/t of ECM) was 5% lower than the UK confinement system (884 kg of CO2-eq/t of ECM) and 7% lower than the US confinement system (898 kg of CO2-eq/t of ECM). However, without grassland carbon sequestration, the grass-based and confinement dairy systems had similar carbon footprints per tonne of ECM. Emission algorithms and allocation of GHG emissions between milk and meat also affected the relative difference and order of dairy system carbon footprints. For instance, depending on the method chosen to allocate emissions between milk and meat, the relative difference between the carbon footprints of grass-based and confinement dairy systems varied by 3 to 22%. This indicates that further harmonization of several aspects of the LCA methodology is required to compare carbon footprints of contrasting dairy systems. In

  15. Occupational risk factors for testicular cancer: a registry-based case-control study in Rhineland Palatinate – Germany

    Science.gov (United States)

    Yousif, Lamyaa; Hammer, Gaël P.; Emrich, Katharina; Blettner, Maria; Zeeb, Hajo

    2013-01-01

    Objectives: Testicular cancer affects mainly men below the age of 50. An association with occupation and social status has been suggested but risk factors are not well understood. A registry-based case-control study focusing on occupation was performed in Germany. Methods: All 348 testicular cancer cases with available gainful occupational information registered between 2000 and 2005; as well as 564 suitable controls (from a pool of other cancers) were drawn from the Cancer Registry of Rhineland-Palatinate. Unconditional logistic regression was used to compute odds ratios (OR) and associated 95% confidence intervals (CI). Results: Slightly elevated OR were observed for technicians and related professionals (OR 1.62, 95% CI 1.00–2.63) and for clerical support workers (OR 1.71, 95% CI 1.14–2.56). This increase was highest in the age group 20–50 for technicians (OR 2.02, 95% CI 1.23–3.33) and clerks (OR 2.00, 95% CI 1.30–3.09), respectively. An association with testicular cancer was observed for no other occupation. Conclusion: An increased risk of testicular cancer was observed for technicians and related professionals and clerical support workers. This could be related to socioeconomic status or sedentary life style, two factors that were identified in previous studies. While the feasibility of a purely registry-based study was shown, missing occupational data and the choice of cancer controls represent challenges to the validity of this approach. PMID:24265602

  16. Public–private partnerships value in bioenergy projects: Economic feasibility analysis based on two case studies

    International Nuclear Information System (INIS)

    Greece and Italy are facing serious energy challenges concerning sustainability and greenhouse gas emissions as well as security of supply and the competitiveness of the internal energy market. These challenges require investments by the public sector, while the countries have seen in the last years their debts rising. A solution to promote bioenergy business, without rising public debt, could be the use of PPP (Public–Private Partnership). This paper presents a methodology to develop agro-energy business using PPP in two rural areas: the municipality of Evropos (in Greece) and the municipality of Montefalco (in Italy). At first biomass availability is studied, then the optimal technology is selected. Once technological issues have been analyzed PPP value for money has to be assessed. Conventional methods to evaluate economic viability of a project are not enough and a Public-Sector Comparator (PSC) has to be calculated. Typical risks of bioenergy projects are identified, estimating their probabilities and consequences. This will lead to associate a monetary value to each risk. Then the identified risks are allocated among private and public partners, establishing synergies. The allocation of risks will have consequences on the preparation of PPP contract and on partner selection procedure. - Highlights: • PPPs can control or reduce risks in bioenergy business. • Development of a methodology for risk allocation in bioenergy projects. • Development of a methodology for risk valuing in bioenergy projects. • A Public-Sector Comparator has been realized for an agro-energy PPP. • Risk allocation has to be clearly indicated in PPP contract

  17. Ontology-based approach for in vivo human connectomics: the medial Brodmann area 6 case study

    Directory of Open Access Journals (Sweden)

    Tristan eMoreau

    2015-04-01

    Full Text Available Different non-invasive neuroimaging modalities and multi-level analysis of human connectomics datasets yield a great amount of heterogeneous data which are hard to integrate into an unified representation. Biomedical ontologies can provide a suitable integrative framework for domain knowledge as well as a tool to facilitate information retrieval, data sharing and data comparisons across scales, modalities and species. Especially, it is urgently needed to fill the gap between neurobiology and in vivo human connectomics in order to better take into account the reality highlighted in Magnetic Resonance Imaging (MRI and relate it to existing brain knowledge. The aim of this study was to create a neuroanatomical ontology, called Human Connectomics Ontology (HCO, in order to represent macroscopic gray matter regions connected with fiber bundles assessed by diffusion tractography and to annotate MRI connectomics datasets acquired in the living human brain. First a neuroanatomical view called NEURO-DL-FMA was extracted from the reference ontology Foundational Model of Anatomy (FMA in order to construct a gross anatomy ontology of the brain. HCO extends NEURO-DL-FMA by introducing entities (such as MR_Node and MR_Route and object properties such as tracto_connects pertaining to MR connectivity. The Web Ontology Language Description Logics (OWL DL formalism was used in order to enable reasoning with common reasoning engines. Moreover, an experimental work was achieved in order to demonstrate how the HCO could be effectively used to address complex queries concerning in vivo MRI connectomics datasets. Indeed, neuroimaging datasets of five healthy subjects were annotated with terms of the HCO and a multi-level analysis of the connectivity patterns assessed by diffusion tractography of the right medial Brodmann Area 6 was achieved using a set of queries. This approach can facilitate comparison of data across scales, modalities and species.

  18. Food safety concerns deriving from the use of silver based food packaging materials: a case study.

    Directory of Open Access Journals (Sweden)

    Alessandra ePezzuto

    2015-10-01

    Full Text Available The formulation of innovative packaging solutions, exerting a functional antimicrobial role in slowing down food spoilage, is expected to have a significant impact on the food industry, allowing both the maintenance of food safety criteria for longer periods and the reduction of food waste. Different materials are considered able to exert the required antimicrobial activity, among which are materials containing silver. However, challenges exist in the application of silver to food contact materials due to knowledge gaps in the production of ingredients, stability of delivery systems in food matrices and health risks caused by the same properties which also offer the benefits. Aims of the present study were to test the effectiveness and suitability of two packaging systems, one of which contained silver, for packaging and storing Stracchino cheese, a typical Italian fresh cheese, and to investigate if there was any potential for consumers to be exposed to silver, via migration from the packaging to the cheese. Results did not show any significant difference in the effectiveness of the packaging systems on packaged Stracchino cheese, excluding that the active packaging systems exerted an inhibitory effect on the growth of spoilage microorganisms. Moreover, silver migrated into the cheese matrix throughout the storage time (24 days. Silver levels in cheese finally exceeded the maximum established level for the migration of a non-authorised substance through a functional barrier (Commission Regulation (EC No. 450/2009. This result poses safety concerns and strongly suggests the need for more research aimed at better characterizing the new packaging materials in terms of their potential impacts on human health and the environment.

  19. Cognitive distortions based on MDS configuration and sketch mapping: a case study in Beijing

    Science.gov (United States)

    Shen, Si; Xue, Lulu; Wu, Lun; Liu, Yu

    2007-06-01

    As an emerging field, cognitive map kept playing a significant role in geography these decades. To date, there are two dominant methods to externalize human's internal cognitive map, namely, multidimensional scaling (MDS) and skech mapping. However, among most recent researches on cognitive map, the differences between both methods are always ignored. The usage of one method over another is still under scrutiny. In order to shed light on the similarity or distinctions of MDS configuration and sketch mapping, we conducted an experiment on Beijing residents by requesting a sketch of the region within 3rd Ring and meanwhile extracting distance estimates between 8 landmarks. Employing the Bidimensional regression along with standard deviational ellipse, we studied the global and local distortions among two kinds of cognitive maps and quantitatively measure the overall and local cognitive maps distortions. Besides, we use Monte Carlo simulation method to calculate the radius of distortion for the Distortion Index (DI). It shows that the average cognitive distortion of habitants in Beijing is 2km to 3km, and the distortion takes 2nd-ring road as a border, displaying a southwest-northeast diagonal stretch and an east-west contracted tendency. The distortion in the two methods is remarkably both correlated with factors, such as travel frequency and years of residence. Comparing two methods, it turned out that sketch map was more consistent with real map, while the distortion orientations of sketch map resembled MDS configuration. Finally, we gave possible reasons with regard to above conclusions and advices for future usage of two methods.

  20. Towards A Model-Based Prognostics Methodology for Electrolytic Capacitors: A Case Study Based on Electrical Overstress Accelerated Aging

    Science.gov (United States)

    Celaya, Jose R.; Kulkarni, Chetan S.; Biswas, Gautam; Goebel, Kai

    2012-01-01

    A remaining useful life prediction methodology for electrolytic capacitors is presented. This methodology is based on the Kalman filter framework and an empirical degradation model. Electrolytic capacitors are used in several applications ranging from power supplies on critical avionics equipment to power drivers for electro-mechanical actuators. These devices are known for their comparatively low reliability and given their criticality in electronics subsystems they are a good candidate for component level prognostics and health management. Prognostics provides a way to assess remaining useful life of a capacitor based on its current state of health and its anticipated future usage and operational conditions. We present here also, experimental results of an accelerated aging test under electrical stresses. The data obtained in this test form the basis for a remaining life prediction algorithm where a model of the degradation process is suggested. This preliminary remaining life prediction algorithm serves as a demonstration of how prognostics methodologies could be used for electrolytic capacitors. In addition, the use degradation progression data from accelerated aging, provides an avenue for validation of applications of the Kalman filter based prognostics methods typically used for remaining useful life predictions in other applications.