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  1. Catalog of NASA-Related Case Studies

    Data.gov (United States)

    National Aeronautics and Space Administration — The OCKO has developed over 50 case studies to enhance learning at workshops, training, retreats and conferences. Case studies make mission knowledge attractive and...

  2. Two Case Studies Related to Total Knee Arthroplasty

    Science.gov (United States)

    Hale, David

    2016-01-01

    Objectives: Report on Two Case Studies related to Total Knee Arthroplasty Previously Discussed by AKS Members Methods: Case Series Case 1: A 76 year old woman requiring a right total knee replacement in the presence of marked dystrophic calcification affecting the quadriceps tendon on a background of having sustained a post operative quadriceps tendon rupture post left TKR in 2013 Case 2: Management issues related to performing a TKR in a 80 year old woman with a possible past history of TB affecting the joint Conclusion: Both procedures went smoothly and particularly as advice was given by AKS members, these are presented largely for feedback.

  3. Teaching the Public Relations Case Studies/Campaigns Class.

    Science.gov (United States)

    Cottone, Laura Perkins

    The public relations case studies/campaigns class entails teaching students how to die and then come back to life. As students must learn to take a critical look at complex public and social issues, teachers should create an environment in which the students feel comfortable with the process of psychological reconstruction. Students must be taught…

  4. Alcohol effects on family relations: a case study.

    Science.gov (United States)

    Reinaldo, Amanda Márcia Dos Santos; Pillon, Sandra Cristina

    2008-01-01

    Problems related to alcohol abuse have been associated to different factors, regardless of the causes attributed to this phenomenon. Alcohol consumption and dependence is considered a public health problem and deserve attention because of the social, work, family, physical, legal and violence-related risks it represents. This study aimed to identify the effects of alcoholism on family relations and, by means of case management, to encourage the recovery of these relationships. The results show that the problems caused by alcohol abuse impose profound suffering to family members, which contributes to high levels of interpersonal conflict, domestic violence, parental inadequacy, child abuse and negligence, financial and legal difficulties, in addition to clinical problems associated to it.

  5. Relations of power in public schools: a case study

    Directory of Open Access Journals (Sweden)

    Maria Custódia Jorge Rocha

    2014-04-01

    Full Text Available In this paper, based on a few authors who see power as a substantive element – instituted power – and others who consider it as an action verb – instituting power (ROCHA, 2007 –, highlighting some types of power relevant in sociological and organizational research on schools, we present empirical data and institutional discourses, enabled by a case study of qualitative nature. Thus, we can say that relations of power in schools both allow the strengthening of hierarchical and asymmetrical relations of power that exist between institutional players and enable the creation of new “circles of power” that can be promptly activated or can be object of a modernization process held in a more or less generalized manner. This may be reinforced and introduced to players/students, our main target of study, as the most legitimate object, superseding all others but not canceling them. The key objective is to present school organization as a highly complex environment, especially when considered in the light of the multiple and cumulative relations of power that emerge and are materialized.

  6. Core and Periphery Relations: A Case Study of the Maya

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    Stephanie M. Teixeira

    2015-08-01

    Full Text Available How do indigenous peoples relate to the core over the longue duree? In this paper, we explore the implications of colonialism from a world-systems perspective, examining interactions in the economic and political structures in addition to the effects of landlessness for indigenous peoples in one case: the Maya. After reviewing world-systems theory and applying it to indigenousness, we discuss Ragin’s (1992 conceptualization of cases and the comparative historical method. Then we introduce the relational concept, a tool that allows us to employ both the comparative historical method and world-systems theory in our analysis of the Maya and their relationship to the state of Mexico. We then present our data, which consist of the economic and political conditions, along with the cultural implications of landholding across time among the Maya and in Mexico. We analyze these data using the relational concept to understand the consequences of colonialism and globalization for the Maya people.

  7. Asperger syndrome related suicidal behavior: two case studies.

    Science.gov (United States)

    Kocourkova, Jana; Dudova, Iva; Koutek, Jiri

    2013-01-01

    Asperger syndrome hinders adaptation to developmental challenges during childhood and adolescence, particularly with regard to interpersonal relationships. Individuals with Asperger syndrome display lack of empathy and limited ability to understand social and emotional exchanges with other people. Individuals with Asperger syndrome are significantly exposed to the risk of suicidal behavior, especially during adolescence. The authors describe cases of suicidal behavior in two adolescent boys with Asperger syndrome.

  8. Asperger syndrome related suicidal behavior: two case studies

    Directory of Open Access Journals (Sweden)

    Kocourkova J

    2013-11-01

    Full Text Available Jana Kocourkova, Iva Dudova, Jiri Koutek Department of Child Psychiatry, Charles University Second Faculty of Medicine, University Hospital Motol, Prague, Czech Republic Abstract: Asperger syndrome hinders adaptation to developmental challenges during childhood and adolescence, particularly with regard to interpersonal relationships. Individuals with Asperger syndrome display lack of empathy and limited ability to understand social and emotional exchanges with other people. Individuals with Asperger syndrome are significantly exposed to the risk of suicidal behavior, especially during adolescence. The authors describe cases of suicidal behavior in two adolescent boys with Asperger syndrome. Keywords: Asperger syndrome, suicidal behavior, adolescence

  9. The Northern Territories: Case Study in Japanese-Soviet Relations.

    Science.gov (United States)

    1982-06-01

    be used in cellulose production. Pumice and perlite are ex- tracted for use in construction materials and road-building. Titanium-magnetic sands are...types (watermelons and tomatoes ) due to the relatively warm climatic conditions. Pigs, sheep, and horses populate most all settlements, and dairy

  10. Race Relations Equal Opportunity Case Studies for Judge Advocates

    Science.gov (United States)

    1975-01-01

    PROBLEMS IN AMERICA. Wiley Press, 1972 (464 pages). 1 10-1 10. Cahn, Edgar S. OUR BROTHER’S KEEPER: THE INDIAN 0 IN WHITE AMERICA. New Community Press...USAGE IN THE UNITED STATES.ý Random House, 1972 (361 pages). 17. Epps, Edgar G. RACE RELATIONS: CURRENT PERSPEC- TIVES. Winthrop Publisher, 1973 (235...Brown, 1971 (489 pages). 10-3 34. Morin , Raul. AMONG THE VALIANT: MEXICAN AMERI- 0 CANS IN WW II AND KOREA. Borden, 1963 (290 pages). 35. Moskos, Charles

  11. Handling uncertainty in relation extraction: a case study on tennis tournament results extraction from tweets

    NARCIS (Netherlands)

    Verburg, J.; Habib, M. B.; Keulen, M. van

    2015-01-01

    Relation extraction involves different types of uncertainty due to the imperfection of the extraction tools and the inherent ambiguity of unstructured text. In this paper, we discuss several ways of handling uncertainties in relation extraction from social media. Our study case is to extract tennis

  12. Semantic Relations between Legal Terms. A Case Study of the Intralingual Relation of Synonymy

    Directory of Open Access Journals (Sweden)

    Matulewska Aleksandra

    2016-06-01

    Full Text Available The author intends to present a possibility of parametrising legal terminology in order to reveal semantic and systemic relations at the intralingual and interlingual levels. The scope of the research comprises selected legal terminology from the following legal systems: Polish, British, American and European Union. The research methods used include: (i the analysis of comparable texts, (ii the method of parametrisation of the legal linguistic reality, (iii the concept of adjusting translation to the communicative needs and requirements of the recipient community. The research hypothesis is that parametrisation of legal terminology in respect of semantic and systemic relations may be a useful tool in organising and comparing terminology for the purpose of legal translation. First the relation of synonymy binding terms at the intralingual and interlingual levels in the light of systemic and genre-related relations is discussed. The proposal is illustrated with examples of legal terms and the networks of relations binding them in English and Polish. The conclusions are that such an approach is systematic and provides a translator with information necessary to render communicatively efficient translations.

  13. Transcriptomic network analysis of micronuclei-related genes: a case study

    DEFF Research Database (Denmark)

    van Leeuwen, D. M.; Pedersen, Marie; Knudsen, Lisbeth E.;

    2011-01-01

    checkpoint and aneuploidy. The MN-related gene network was tested against a transcriptomics case study associated with MN measurements. In this case study, transcriptomic data from children and adults differentially exposed to ambient air pollution in the Czech Republic were analysed and visualised......Mechanistically relevant information on responses of humans to xenobiotic exposure in relation to chemically induced biological effects, such as micronuclei (MN) formation can be obtained through large-scale transcriptomics studies. Network analysis may enhance the analysis and visualisation...... of such data. Therefore, this study aimed to develop a 'MN formation' network based on a priori knowledge, by using the pathway tool MetaCore. The gene network contained 27 genes and three gene complexes that are related to processes involved in MN formation, e.g. spindle assembly checkpoint, cell cycle...

  14. Preparing Public Relations and Advertising Students for the 21st Century: A Case Study.

    Science.gov (United States)

    Carroll, Robert A.

    In 1993, the Task Force on Integrated Communications reported that public relations and advertising students would better be prepared to enter a changing communications industry through an "integrated" curriculum. This paper is a case study of how one university has attempted to meet that challenge. The work has resulted in the development of an…

  15. Alcohol Consumption-Related Metabolites in Relation to Colorectal Cancer and Adenoma: Two Case-Control Studies Using Serum Biomarkers.

    Science.gov (United States)

    Troche, Jose Ramon; Mayne, Susan T; Freedman, Neal D; Shebl, Fatma M; Guertin, Kristin A; Cross, Amanda J; Abnet, Christian C

    2016-01-01

    Alcohol is a known carcinogen that may be associated with colorectal cancer. However, most epidemiologic studies assess alcoholic beverage consumption using self-reported data, leading to potential exposure misclassification. Biomarkers of alcohol consumption may provide an alternative, complementary approach that reduces misclassification and incorporates individual differences in alcohol metabolism. Therefore, we evaluated the relationship between previously identified alcohol consumption-related metabolites and colorectal cancer and adenoma using serum metabolomics data from two studies. Data on colorectal cancer were obtained from a nested case-control study of 502 US adults (252 cases, 250 controls) within the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Data on colorectal adenoma were obtained from a case-control study of 197 US adults (120 cases, 77 controls) from the Navy Colon Adenoma Study. Unconditional multivariable logistic regression models were fit to calculate odds ratios (OR) and 95% confidence intervals (CI) for eight alcohol consumption-related metabolites identified in a previous analysis: ethyl glucuronide; 4-androstene-3beta,17beta-diol disulfate 1; 5-alpha-androstan-3beta,17beta-diol disulfate; 16-hydroxypalmitate; bilirubin (E,Z or Z,E); cyclo (-leu-pro); dihomo-linoleate (20:2n6); and palmitoleate (16:1n7). We found no clear association between these alcohol consumption-related metabolites and either endpoint. However, we did observe an inverse association between cyclo (-leu-pro) and colorectal adenoma that was only observed in the highest metabolite quantile (OR 4th vs. 1st Quantile = 0.30, 95% CI: 0.12-0.78; P-trend = 0.047), but no association for colorectal cancer. In conclusion, there were no adverse associations between alcohol consumption-related metabolites and colorectal cancer or adenoma.

  16. Technology Strategy and Industrial Relations: Case Studies of Japanese Multinationals in the United States

    OpenAIRE

    1983-01-01

    Eight case studies of U.S. manufacturing subsidiaries of Japanese multinationals are analyzed in terms of variations in competitive strategies and industrial relations practices. Based on data collected in 1980 on-site visits, each firm is reviewed in light of the technology contributions coming from the Japanese parent and is categorized as having product-, process-, and/or management-centered technology strategies. The industrial relations practices are also grouped according to similaritie...

  17. Competition between word order and case-marking in interpreting grammatical relations: a case study in multilingual acquisition.

    Science.gov (United States)

    O'Shannessy, Carmel

    2011-09-01

    The study examines strategies multilingual children use to interpret grammatical relations, focusing on their two primary languages, Lajamanu Warlpiri and Light Warlpiri. Both languages use mixed systems for indicating grammatical relations. In both languages ergative-absolutive case-marking indicates core arguments, but to different extents in each language. In Lajamanu Warlpiri, pronominal clitics in a nominative-accusative pattern also indicate core arguments, and in Light Warlpiri word order in a nominative-accusative pattern partially does so. The study asks which sentence interpretation strategies children rely on most, when they learn to rely on them and whether cross-linguistic influences are seen. Children aged 5;0, 7;0 and 9;0 and adults saw paired, animated events simultaneously on video and heard a transitive sentence spoken. The participants pointed to the event depicted by the sentence heard. Adults used a case-marking strategy consistently in both languages. Children initially used both case-marking and word order strategies, but used case-marking more often as age increased.

  18. Excess relative risk as an effect measure in case-control studies of rare diseases.

    Directory of Open Access Journals (Sweden)

    Wen-Chung Lee

    Full Text Available Epidemiologists often use ratio-type indices (rate ratio, risk ratio and odds ratio to quantify the association between exposure and disease. By comparison, less attention has been paid to effect measures on a difference scale (excess rate or excess risk. The excess relative risk (ERR used primarily by radiation epidemiologists is of peculiar interest here, in that it involves both difference and ratio operations. The ERR index (but not the difference-type indices is estimable in case-control studies. Using the theory of sufficient component cause model, the author shows that when there is no mechanistic interaction (no synergism in the sufficient cause sense between the exposure under study and the stratifying variable, the ERR index (but not the ratio-type indices in a rare-disease case-control setting should remain constant across strata and can therefore be regarded as a common effect parameter. By exploiting this homogeneity property, the related attributable fraction indices can also be estimated with greater precision. The author demonstrates the methodology (SAS codes provided using a case-control dataset, and shows that ERR preserves the logical properties of the ratio-type indices. In light of the many desirable properties of the ERR index, the author advocates its use as an effect measure in case-control studies of rare diseases.

  19. Excess relative risk as an effect measure in case-control studies of rare diseases.

    Science.gov (United States)

    Lee, Wen-Chung

    2014-01-01

    Epidemiologists often use ratio-type indices (rate ratio, risk ratio and odds ratio) to quantify the association between exposure and disease. By comparison, less attention has been paid to effect measures on a difference scale (excess rate or excess risk). The excess relative risk (ERR) used primarily by radiation epidemiologists is of peculiar interest here, in that it involves both difference and ratio operations. The ERR index (but not the difference-type indices) is estimable in case-control studies. Using the theory of sufficient component cause model, the author shows that when there is no mechanistic interaction (no synergism in the sufficient cause sense) between the exposure under study and the stratifying variable, the ERR index (but not the ratio-type indices) in a rare-disease case-control setting should remain constant across strata and can therefore be regarded as a common effect parameter. By exploiting this homogeneity property, the related attributable fraction indices can also be estimated with greater precision. The author demonstrates the methodology (SAS codes provided) using a case-control dataset, and shows that ERR preserves the logical properties of the ratio-type indices. In light of the many desirable properties of the ERR index, the author advocates its use as an effect measure in case-control studies of rare diseases.

  20. Diazepam use in relation to breast cancer: results from two case-control studies.

    Science.gov (United States)

    Kaufman, D W; Werler, M M; Palmer, J R; Rosenberg, L; Stolley, P D; Warshauer, M E; Clarke, E A; Miller, D R; Shapiro, S

    1990-03-01

    The relation between diazepam use and breast cancer was explored in two case-control studies. The first (1981-1987) was a hospital-based study in the United States of 3,078 cases of breast cancer, 1,259 controls with other malignancies, and 672 controls with nonmalignant conditions. The relative risk estimates for regular diazepam use (at least 4 days per week for at least 6 months) that antedated the diagnosis of breast cancer by at least 12 months were 1.0 (95% confidence interval (CI) 0.6-1.7) using the cancer controls and 0.8 (95% CI 0.4-1.8) using the noncancer controls. Risk factors for breast cancer were taken into account in the estimates. There was no association for regular use lasting at least 5 years or for regular use that took place exclusively in the recent or more distant past. The second study (1982-1986), conducted in Toronto, Ontario, Canada, was community-based, and included 607 cases of breast cancer and 1,214 neighbor controls selected from municipal voting and census records. After control of confounding, the relative risk estimate for regular diazepam use was 0.8 (95% CI 0.5-1.3). Again, there was no association for long-term, past, or recent regular use. The results of both studies suggest that regular diazepam use does not increase the risk of breast cancer. The findings are strengthened by the similarity of the results using three different control groups--women with cancer, women with nonmalignant conditions, and neighbors.

  1. Predictors of delayed recovery following pediatric sports-related concussion: a case-control study.

    Science.gov (United States)

    Miller, Joseph H; Gill, Clarence; Kuhn, Elizabeth N; Rocque, Brandon G; Menendez, Joshua Y; O'Neill, Jilian A; Agee, Bonita S; Brown, Steven T; Crowther, Marshall; Davis, R Drew; Ferguson, Drew; Johnston, James M

    2016-04-01

    OBJECT Pediatric sports-related concussions are a growing public health concern. The factors that determine injury severity and time to recovery following these concussions are poorly understood. Previous studies suggest that initial symptom severity and diagnosis of attention deficit hyperactivity disorder (ADHD) are predictors of prolonged recovery (> 28 days) after pediatric sports-related concussions. Further analysis of baseline patient characteristics may allow for a more accurate prediction of which patients are at risk for delayed recovery after a sports-related concussion. METHODS The authors performed a single-center retrospective case-control study involving patients cared for at the multidisciplinary Concussion Clinic at Children's of Alabama between August 2011 and January 2013. Patient demographic data, medical history, sport concussion assessment tool 2 (SCAT2) and symptom severity scores, injury characteristics, and patient balance assessments were analyzed for each outcome group. The control group consisted of patients whose symptoms resolved within 28 days. The case group included patients whose symptoms persisted for more than 28 days. The presence or absence of the SCAT2 assessment had a modifying effect on the risk for delayed recovery; therefore, stratum-specific analyses were conducted for patients with recorded SCAT2 scores and for patients without SCAT2 scores. Unadjusted ORs and adjusted ORs (aORs) for an association of delayed recovery outcome with specific risk factors were calculated with logistic regression analysis. RESULTS A total of 294 patients met the inclusion criteria of the study. The case and control groups did not statistically significantly differ in age (p = 0.7). For the patients who had received SCAT2 assessments, a previous history of concussion (aOR 3.67, 95% CI 1.51-8.95), presenting SCAT2 score recovery (aOR 4.41, 95% CI 1.93-10.07 and aOR 3.87, 95% CI 1.13-13.24, respectively). Concussions resulting from playing a

  2. Two-stage case-control association study of dopamine-related genes and migraine

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    Pardo Julio

    2009-09-01

    Full Text Available Abstract Background We previously reported risk haplotypes for two genes related with serotonin and dopamine metabolism: MAOA in migraine without aura and DDC in migraine with aura. Herein we investigate the contribution to migraine susceptibility of eight additional genes involved in dopamine neurotransmission. Methods We performed a two-stage case-control association study of 50 tag single nucleotide polymorphisms (SNPs, selected according to genetic coverage parameters. The first analysis consisted of 263 patients and 274 controls and the replication study was composed by 259 cases and 287 controls. All cases were diagnosed according to ICHD-II criteria, were Spanish Caucasian, and were sex-matched with control subjects. Results Single-marker analysis of the first population identified nominal associations of five genes with migraine. After applying a false discovery rate correction of 10%, the differences remained significant only for DRD2 (rs2283265 and TH (rs2070762. Multiple-marker analysis identified a five-marker T-C-G-C-G (rs12363125-rs2283265-rs2242592-rs1554929-rs2234689 risk haplotype in DRD2 and a two-marker A-C (rs6356-rs2070762 risk haplotype in TH that remained significant after correction by permutations. These results, however, were not replicated in the second independent cohort. Conclusion The present study does not support the involvement of the DRD1, DRD2, DRD3, DRD5, DBH, COMT, SLC6A3 and TH genes in the genetic predisposition to migraine in the Spanish population.

  3. Clinical and pathological study on 10 cases of cerebral lobe hemorrhage related with cerebral amyloid angiopathy

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    Xiao-qi LI

    2015-07-01

    Full Text Available Objective To summarize the clinical data and pathological features of 10 cases of cerebral lobar hemorrhage related with cerebral amyloid angiopathy (CAA diagnosed pathologically, thereby to improve the knowledge and diagnosis of the disease. Methods The clinical data of 10 cases of cerebral lobar hemorrhage related with CAA, collected in the General Hospital of Shenyang Command from 1983 up to now, were retrospectively analyzed, and the clinical and neuropathological features of these cases were summarized. Results Of the 10 patients, 2 suffered from single lobar hemorrhage and 8 multiple lobar hemorrhage, all of them were confirmed pathologically to have ruptured into the subarachnoid space. Pathological examination revealed microaneurysm in 2 cases, "double barrel" change in 4 cases, multiple arteriolar clusters in 5 cases, obliterative onion-liked intima change in 4 cases, and fibrinoid necrosis of vessel wall in 7 cases. In addition, neurofibrillary tangles were found in 8 cases, and senile plaque was observed in 5 cases. Conclusions Cerebral lobar hemorrhage related with CAA is mainly located in the parietal, temporal and occipital lobes, readily breaking into the subarachnoid space, and it is often multiple and recurrent. The CAA associated microvasculopathy was found frequently in the autopsy sample of CAA related cerebral lobar hemorrhage, and it may contribute to the pathogenesis of cerebral hemorrhage. DOI: 10.11855/j.issn.0577-7402.2015.07.04

  4. Human papillomavirus infection is not related with prostatitis-related symptoms: results from a case-control study

    Directory of Open Access Journals (Sweden)

    Riccardo Bartoletti

    2014-04-01

    Full Text Available PurposeTo investigate the relationship between human papillomavirus (HPV infection and prostatitis-related symptoms.Materials and MethodsAll young heterosexual patients with prostatitis-related symptoms attending the same Center from January 2005 to December 2010 were eligible for this case-control study. Sexually active asymptomatic men were considered as the control group. All subjects underwent clinical examination, Meares-Stamey test and DNA-HPV test. Patients with prostatitis-related symptoms and asymptomatic men were compared in terms of HPV prevalence. Moreover, multivariable Cox proportional hazards regression analysis was performed to determine the association between HPV infection and prostatitis-related symptoms.ResultsOverall, 814 out of 2,938 patients (27.7% and 292 out of 1,081 controls (27.0% proved positive to HPV. The HPV genotype distribution was as follows: HR-HPV 478 (43.3%, PHR-HPV 77 (6.9%, LR-HPV 187 (16.9% and PNG-HPV 364 (32.9%. The most common HPV genotypes were: 6, 11, 16, 26, 51, 53 and 81. No difference was found between the two groups in terms of HPV infection (OR 1.03; 95% CI 0.88-1.22; p = 0.66. We noted a statistically significant increase in HPV infection over the period 2005 to 2010 (p < 0.001 in both groups. Moreover, we found a statistically significant increase in HPV 16 frequency from 2005 to 2010 (p = 0.002.ConclusionsThis study highlights that prostatitis-like symptoms are unrelated to HPV infection. Secondary, we highlight the high prevalence of asymptomatic HPV infection among young heterosexual men.

  5. Case studies of energy information systems and related technology: Operational practices, costs, and benefits

    Energy Technology Data Exchange (ETDEWEB)

    Motegi, Naoya; Piette, Mary Ann; Kinney, Satkartar; Dewey, Jim

    2003-09-02

    Energy Information Systems (EIS), which can monitor and analyze building energy consumption and related data throughout the Internet, have been increasing in use over the last decade. Though EIS developers describe the capabilities, costs, and benefits of EIS, many of these descriptions are idealized and often insufficient for potential users to evaluate cost, benefit and operational usefulness. LBNL has conducted a series of case studies of existing EIS and related technology installations. This study explored the following questions: (1) How is the EIS used in day-to-day operation? (2) What are the costs and benefits of an EIS? (3) Where do the energy savings come from? This paper reviews the process of these technologies from installation through energy management practice. The study is based on interviews with operators and energy managers who use EIS. Analysis of energy data trended by EIS and utility bills was also conducted to measure the benefit. This paper explores common uses and findings to identify energy savings attributable to EIS, and discusses non-energy benefits as well. This paper also addresses technologies related to EIS that have been demonstrated and evaluated by LBNL.

  6. Analysis of postural load during tasks related to milking cows-a case study.

    Science.gov (United States)

    Groborz, Anna; Tokarski, Tomasz; Roman-Liu, Danuta

    2011-01-01

    The aim of this study was to analyse postural load during tasks related to milking cows of 2 farmers on 2 different farms (one with a manual milk transport system, the other with a fully automated milk transport system) as a case study. The participants were full-time farmers, they were both healthy and experienced in their job. The Ovako Working Posture Analyzing System (OWAS) was used to evaluate postural load and postural risk. Postural load was medium for the farmer on the farm with a manual milk transport system and high for the farmer working on the farm with a fully automated milk transport system. Thus, it can be concluded that a higher level of farm mechanization not always mean that the farmer's postural load is lower, but limitation of OWAS should be considered.

  7. The relative frequency of odontogenic tumors: A study of 376 cases in a Brazilian population

    Science.gov (United States)

    Lima-Verde-Osterne, Rafael; Turatti, Eveline; Cordeiro-Teixeira, Renata

    2017-01-01

    Background Odontogenic tumors (OTs) are rare lesions, exclusive of the jaws, that are derived from epithelial and/or ectomesenchymal elements of the tooth-forming apparatus. Their biological behavior is heterogeneous, including hamartomatous tissue proliferation, benign nonaggressive and aggressive neoplasms, and malignant tumors with metastatic capacity. The aim of this study was to describe the relative frequency of odontogenic tumors in a Brazilian population. In addition, a review of the literature identified studies on odontogenic tumors that follow the 2005 World Health Organization. Material and Methods A total of 376 cases of odontogenic tumors from an oral pathology service were reviewed about age, gender, anatomic site and histologic diagnosis. Results Keratocystic odontogenic tumors (31.6%) were the most common, followed by ameloblastoma (28.5%), and odontoma (22.6%). The mean age was 32.2 years, and more than half the patients (52.1%) were in the second and third decades of life. The male to female ratio was 1:1.37, with a maxilla to mandible ratio of 1:2.08. Conclusions The variation in relative frequency of tumors observed among the several series, including the present study, is probably due in part to cultural differences between geographic areas but also to the study design. Key words:Pathology, epidemiology, odontogenic tumors. PMID:28160576

  8. Interdisciplinary team discussion on work environment issues related to low back disability: a multiple case study.

    Science.gov (United States)

    Costa-Black, Kátia M; Durand, Marie-José; Imbeau, Daniel; Baril, Raymond; Loisel, Patrick

    2007-01-01

    From both a social and cost-benefit perspective, disability prevention and associated management strategies for assisting employees with back pain are only successful if they address critical return-to-work (RTW) determining factors present in the workplace, including ergonomic factors. Despite our current knowledge of the importance of an integrated team approach targeting these factors, questions remain regarding the conceptual framework adopted by contemporary rehabilitation teams as it relates to work-oriented interventions to accommodate employees back to work. The purpose of this study was to explore and describe the work environment issues discussed by an interdisciplinary team engaged in the work rehabilitation process of low back disability cases. A qualitative content analysis was conducted for 10 sample cases that underwent a rehabilitation program in Quebec (Canada). Drawing on the results of these analyses, a framework representing a synopsis of practitioners' involvement in the person-environment dynamic is presented and discussed. This study makes a unique contribution to the understanding of the 'real-life' content of an interdisciplinary activity in disability management, thus, helping rehabilitation practitioners to build knowledge on the practical application of a cross-disciplinary framework to address work environment issues during the RTW process of those patients sick-listed due to back pain.

  9. Immunoglobulin G4-related prostatitis: A case-control study focusing on clinical and pathologic characteristics

    NARCIS (Netherlands)

    J. Buijs (Jorie); L. Maillette De Buy Wenniger (Lucas); G.J.H.L. Leenders (Geert); J. Verheij (Joanne); I. van Onna (Ilze); B.E. Hansen (Bettina); M. van Heerde (Marianne); N.C. Krak (Nanda); U. Beuers (Ulrich); M.J. Bruno (Marco); H.R. van Buuren (Henk)

    2014-01-01

    markdownabstractOBJECTIVE To evaluate the occurrence and histopathologic characteristics of immunoglobulin G4 (IgG4)- related prostatic involvement in patients diagnosed with autoimmune pancreatitis. METHODS Nine cases of IgG4-related prostatitis were identified among 117 men in the autoimmune pan

  10. The Time - Space Analysis of Social Pathologies Related to Drugs (Case Study: Tehran 12th District

    Directory of Open Access Journals (Sweden)

    Ali Zangiabadi

    2015-09-01

    th District have been considered as point events.     Discussion of Results & Conclusions   Among Iran's cities, Tehran has the highest rate of social pathologies because of specific, spatial, physical and social conditions. This positive relationship between population growth and increase in the rate of social Pathologies can be regarded as a result of quantitative increase in the city's population. So it is essential to, with scientific methods and new technologies, identify place-time circumstances in which crimes are committed in Tehran. Tehran's 12th district with 1600 hectares equivalent to 2/7 percent of the total area of Tehran has allocated according to statistics 3.17 percent of the total population of Tehran. Evaluation of the relative density of population in 12th district show that in these area 154.5 people live per hectare, while the relative density of population in Tehran is 131.6 people per hectare. Therefore relative density of population in district 12 of Tehran is greater than the average density in Tehran city.   The findings show that although district 12, only has allocated 2.7 percent of the land area, but the most percentage occurrence of social pathologies occurred in this area of Tehran. In other words, from 6006 cases of studied crime in this study that occurred in Tehran, about 560 cases, occurred in the 12th district.   Based on the time analysis which determines the type and extent of crime in the 12th district, the peak time and the time center of gravity of crimes is 13 and Wednesday, with frequency of 10-8 crime events in this hour and day. Also on the same time at 12:30 to 13:30, 8-6 cases of crime occurs. The findings show that the average center of crimes related to drugs on 12 district is coincided largely with the geographical center of this region, on the streets of Nasser Khosrow , leading to the 15 Khordad street. Standard deviation ellipse of this type of crimes has mode circle, which represents the geographic

  11. Are antibiotics related to oral combination contraceptive failures in the Netherlands? A case-crossover study

    NARCIS (Netherlands)

    Koopmans, P.C.; Bos, J.H.; de Jong-van den Berg, L.T.

    2012-01-01

    Purpose To investigate whether there is an association between use of antibiotics and breakthrough pregnancy. Methods The study was performed in a population-based prescription database (IADB.nl). We computed case-crossover odds ratios of 397 cases of defined breakthrough pregnancy comparing the use

  12. The effect on organizational change on relational coordination – a multi case study

    DEFF Research Database (Denmark)

    Edwards, Kasper; Lundstrøm, Sanne Lykke

    2014-01-01

    This study presents results from an original empirical study of 11 organizational change projects in different wards at two Danish hospitals. The purpose of the study was to study was to study changes in relation coordination as a consequence of organizational change. We measured relational...... coordination before and after the organizational change using the 7 question relational coordination questionnaire. A group of employees were interviewed after the change project to uncover the nature and extent of the changes. We find that organizations’ relational coordination score change very little – even...... for organizational change that introduces new work relations and new processes....

  13. Anions Govern Cell Volume: A Case Study of Relative Astrocytic and Neuronal Swelling in Spreading Depolarization.

    Directory of Open Access Journals (Sweden)

    Niklas Hübel

    Full Text Available Cell volume changes are ubiquitous in normal and pathological activity of the brain. Nevertheless, we know little about the dynamics of cell and tissue swelling, and the differential changes in the volumes of neurons and glia during pathological states such as spreading depolarizations (SD under ischemic and non-ischemic conditions, and epileptic seizures. By combining the Hodgkin-Huxley type spiking dynamics, dynamic ion concentrations, and simultaneous neuronal and astroglial volume changes into a comprehensive model, we elucidate why glial cells swell more than neurons in SD and the special case of anoxic depolarization (AD, and explore the relative contributions of the two cell types to tissue swelling. Our results demonstrate that anion channels, particularly Cl-, are intrinsically connected to cell swelling and blocking these currents prevents changes in cell volume. The model is based on a simple and physiologically realistic description. We introduce model extensions that are either derived purely from first physical principles of electroneutrality, osmosis, and conservation of particles, or by a phenomenological combination of these principles and known physiological facts. This work provides insights into numerous studies related to neuronal and glial volume changes in SD that otherwise seem contradictory, and is broadly applicable to swelling in other cell types and conditions.

  14. Case studies on heat stress related perceptions in different industrial sectors in southern India

    Directory of Open Access Journals (Sweden)

    Kalpana Balakrishnan

    2010-11-01

    Full Text Available Linkages between thermal loads and its physiological consequences have been widely studied in non-tropical developed country settings. In many developing countries like India, despite the widespread recognition of the problem, limited attempts have been made to estimate health impacts related to occupational heat stress and fewer yet to link heat stress with potential productivity losses. This is reflected in the ubiquity of workplaces with limited or no controls to reduce exposures. As a prelude to understanding the feasibility of alternative interventions in different industrial sectors, we present case studies from 10 different industrial units in Tamil Nadu, Chennai, which describe perceptions of occupational heat stress among the workers and supervisors/management.Units were selected from among those who had previously requested an assessment of workplace heat stress exposure at select locations as part of routine industrial hygiene services provided by the investigators. Since the earlier measurements were performed in response to a management request, all units were revisited to generate a simple job and process profile using checklists in order to understand the overall heat exposure situation in the concerned unit. This was followed by a simple questionnaire administration to a small subsample of employees to evaluate the perceptions of workers and supervisors/management. Finally, we retrieved available quantitative data from previous measurements of heat stress at these units to correlate prevalence of exposures with respective perceptions.Results indicate that the existing level of controls may not be sufficient for managing work-related heat stress in any of the sectors studied, with wide variations in perceived risks. There was a noticeable disconnect between worker's perceptions and their ability to secure workplace improvements related to heat stress from the management. Wider availability of engineering and administrative

  15. Case-control study of gadodiamide-related nephrogenic systemic fibrosis

    DEFF Research Database (Denmark)

    Marckmann, Peter; Skov, Lone; Rossen, Kristian;

    2007-01-01

    BACKGROUND: Nephrogenic systemic fibrosis may be caused by gadolinium (Gd)-containing magnetic resonance imaging contrast agents. Most reported cases were associated with one particular agent, gadodiamide. Yet, unidentified cofactors might explain why only a minority of renal failure patients...... higher serum concentrations of ionized calcium and phosphate than controls and tended to receive higher doses of epoietin-beta than controls at time of exposure. Severe cases were treated with higher doses of epoietin-beta than non-severe cases at exposure (10.8 vs 4.4 10(3) IU/week, P = 0.......02). CONCLUSIONS: Increasing cumulative gadodiamide exposure, high-dose epoietin-beta treatment, and higher serum concentrations of ionized calcium and phosphate increase the risk of gadodiamide-related nephrogenic systemic fibrosis in renal failure patients. Severe cases seem to develop primarily among patients...

  16. Insulin versus oral agents in the management of Cystic Fibrosis Related Diabetes: a case based study

    Directory of Open Access Journals (Sweden)

    Langdon Leora J

    2006-06-01

    Full Text Available Abstract Background Insulin is the recommend therapeutic agent of choice for the management of Cystic Fibrosis Related Diabetes (CFRD, despite only sub-optimal reductions in glycemic control and increased morbidity and mortality reported by centers using this agent. The newer insulin sensitizing agents demonstrated to have anti-inflammatory mechanisms may provide an alternative management option for CFRD. Methods A prospective case based therapeutic comparison between insulin, sulfonylurea, metformin and thiazolidinedione was observed over one decade with 20 CFRD patients diagnosed using American Diabetes Association guideline standards. Patients entering the study elected treatment based on risk and benefit information provided for treatment options. Patients receiving organ transplant or requiring combination diabetic medications were excluded from the study. Results No statistical advantage was achieved regarding overall glycemic control for oral agents over insulin. Additional outcome measures including changes in weight, liver function testing and FEV1 were not statistically significant. Conclusion Insulin alone may not be the only therapeutic option in managing CFRD. Oral hypoglycemic agents were equally effective in treating CFRD and may provide an alternative class of agents for patients reluctant in using insulin.

  17. Not so ‘invisible’: A Qualitative Case Study Exploring Gender Relations and Farm Management Software

    Directory of Open Access Journals (Sweden)

    Dale Carolyn Mackrell

    2010-01-01

    Full Text Available This qualitative case study explored farm management practices by women cotton growers who used computer-based information systems, most particularly the agricultural farm management software, CottonLOGIC, within the Australian cotton industry. This study found that, although gender differences and inequalities persist in rural parts of the region, the agency of women cotton growers ensures not only a sustainable future for themselves and their families, but also for the broader cotton industry as a whole. The use of farm management software by women cotton farmers was informed by Connell’s theoretical framework of gender relations (2002. The findings suggested that, women’s active participation in family farm partnerships and their acquisition of technological skills through the use of farm management software like CottonLOGIC, meant that all cotton growers benefit through the feminizing of specific farm management practices in family farm enterprises. This, therefore, has significant implications for developing the cotton industry into a truly sustainable entity.

  18. Investigating Autism-Related Symptoms in Children with Prader-Willi Syndrome: A Case Study

    Science.gov (United States)

    Bennett, Jeffrey A.; Hodgetts, Sandra; Mackenzie, Michelle L.; Haqq, Andrea M.; Zwaigenbaum, Lonnie

    2017-01-01

    Prader-Willi syndrome (PWS), a rare genetic disorder caused by the lack of expression of paternal genes from chromosome 15q11-13, has been investigated for autism spectrum disorder (ASD) symptomatology in various studies. However, previous findings have been variable, and no studies investigating ASD symptomatology in PWS have exclusively studied children. We aimed to characterize social communication functioning and other ASD-related symptoms in children with PWS, and assessed agreement across measures and rates of ASD diagnosis. Measures included the Autism Diagnostic Observation Schedule-2 (ADOS-2), the Social Communication Questionnaire (SCQ), Social Responsiveness Scale-2 (SRS-2), Social Skills Improvement System-Rating Scales (SSIS-RS), and the Vineland Adaptive Behavioral Scales-II (VABS-II). General adaptive and intellectual skills were also assessed. Clinical best estimate (CBE) diagnosis was determined by an experienced developmental pediatrician, based on history and review of all available study measures, and taking into account overall developmental level. Participants included 10 children with PWS, aged 3 to 12 years. Three of the 10 children were male and genetic subtypes were two deletion (DEL) and eight uniparental disomy (UPD) (with a total of 6 female UPD cases). Although 8 of the 10 children exceeded cut-offs on at least one of the ASD assessments, agreement between parent questionnaires (SCQ, SRS-2, SSIS-RS) and observational assessment (ADOS-2) was very poor. None of the children were assigned a CBE diagnosis of ASD, with the caveat that the risk may have been lower because of the predominance of girls in the sample. The lack of agreement between the assessments emphasizes the complexity of interpreting ASD symptom measures in children with PWS. PMID:28264487

  19. Investigating Autism-Related Symptoms in Children with Prader-Willi Syndrome: A Case Study

    Directory of Open Access Journals (Sweden)

    Jeffrey A. Bennett

    2017-02-01

    Full Text Available Prader-Willi syndrome (PWS, a rare genetic disorder caused by the lack of expression of paternal genes from chromosome 15q11-13, has been investigated for autism spectrum disorder (ASD symptomatology in various studies. However, previous findings have been variable, and no studies investigating ASD symptomatology in PWS have exclusively studied children. We aimed to characterize social communication functioning and other ASD-related symptoms in children with PWS, and assessed agreement across measures and rates of ASD diagnosis. Measures included the Autism Diagnostic Observation Schedule-2 (ADOS-2, the Social Communication Questionnaire (SCQ, Social Responsiveness Scale-2 (SRS-2, Social Skills Improvement System-Rating Scales (SSIS-RS, and the Vineland Adaptive Behavioral Scales-II (VABS-II. General adaptive and intellectual skills were also assessed. Clinical best estimate (CBE diagnosis was determined by an experienced developmental pediatrician, based on history and review of all available study measures, and taking into account overall developmental level. Participants included 10 children with PWS, aged 3 to 12 years. Three of the 10 children were male and genetic subtypes were two deletion (DEL and eight uniparental disomy (UPD (with a total of 6 female UPD cases. Although 8 of the 10 children exceeded cut-offs on at least one of the ASD assessments, agreement between parent questionnaires (SCQ, SRS-2, SSIS-RS and observational assessment (ADOS-2 was very poor. None of the children were assigned a CBE diagnosis of ASD, with the caveat that the risk may have been lower because of the predominance of girls in the sample. The lack of agreement between the assessments emphasizes the complexity of interpreting ASD symptom measures in children with PWS.

  20. The timing of drug funding announcements relative to elections: a case study involving dementia medications.

    Directory of Open Access Journals (Sweden)

    Sudeep S Gill

    Full Text Available BACKGROUND: Following initial regulatory approval of prescription drugs, many factors may influence insurers and health systems when they decide whether to add these drugs to their formularies. The role of political pressures on drug funding announcements has received relatively little attention, and elections represent an especially powerful form of political pressure. We examined the temporal relationship between decisions to add one class of drugs to publicly funded formularies in Canada's ten provinces and elections in these jurisdictions. METHODS: Dates of provincial formulary listings for cholinesterase inhibitors, which are drugs used to treat Alzheimer's disease and related dementias, were compared to the dates of provincial elections. Medical journal articles, media reports, and proceedings from provincial legislatures were reviewed to assemble information on the chronology of events. We tested whether there was a statistically significant increase in the probability of drug funding announcements within the 60-day intervals preceding provincial elections. RESULTS: Decisions to fund the cholinesterase inhibitors were made over a nine-year span from 1999 to 2007 in the ten provinces. In four of ten provinces, the drugs were added to formularies in a time period closely preceding a provincial election (P = 0.032; funding announcements in these provinces were made between 2 and 47 days prior to elections. Statements made in provincial legislatures highlight the key role of political pressures in these funding announcements. CONCLUSIONS: Impending elections appeared to affect the timing of drug funding announcements in this case study. Despite an established structure for evidence-based decision-making, drug funding remains a complex process open to influence from many sources. Awareness of such influences is critical to maintain effective drug policy and public health decision-making.

  1. EFFECTIVENESS OF DICLOFENAC SODIUM PHONOPHORESIS TO RESOLVE PAIN RELATED TO FACET SYNDROME: A CASE STUDY

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    Deepak B. Anap

    2013-04-01

    Full Text Available A single case study design was used to investigate the effects sodium diclofenac (Voltaren Emulgel®, Novartis phonophoresis and back stabilization exercises for lumbar facet syndrome. A visual analogue scale was used to measure pain, Modified Oswestery disability questionnaire was used to measure disability and Sorensen test was used to measure back endurance. The study involved three phases in an ABC design. They were 1- week pre assessment, 2-treatment phase and 2 week post treatment assessment phase and 2 weeks follow up phase. The technique resulted in reduction in pain, reduction in disability and improvement in core muscle strength in case of Facet syndrome.Although single case study design limits generalization of the results, it does provide evidence of the beneficial response obtained by use of Phonophoresis and stabilization exercises in Facet syndrome patients.

  2. Familial aggregation of Alzheimer's disease and related disorders: A collaborative re-analysis of case-control studies

    NARCIS (Netherlands)

    C.M. van Duijn (Cock); D.G. Clayton (David); V. Chandra; L. Fratiglioni (Laura); A.B. Graves; A. Heyman; A.F. Jorm; E. Kokmen (Emre); K. Kondo; J.A. Mortimer; W.A. Rocca; S.L. Shalat; H. Soininen; A. Hofman (Albert)

    1991-01-01

    textabstractCase-control studies of Alzheimer's disease were re-analysed to examine the association of Alzheimer's disease with family history in first degree relatives of dementia, Down's syndrome and Parkinson's disease. Overall, the relative risk of Alzheimer's disease for those with at least one

  3. Relational Underpinnings and Professionality--A Case Study of a Teacher's Practices Involving Students with Experiences of School Failure

    Science.gov (United States)

    Frelin, Anneli

    2015-01-01

    Relational features of the educational environment, such as positive teacher-student relationships, are important for students' academic success. This case study explores the relational practices of a teacher who negotiates educational relationships with students who have a history of school failure. "Gunilla", a secondary school teacher…

  4. Use of benzodiazepines or benzodiazepine related drugs and the risk of cancer: a population-based case-control study

    DEFF Research Database (Denmark)

    Pottegård, Anton; Friis, Søren; Andersen, Morten

    2013-01-01

    AIM: Studies of the carcinogenic potential of benzodiazepines and related drugs (BZRD) have been equivocal. A recent study reported a 35% excess cancer risk among users of hypnotics, including benzodiazepines. METHOD: Using Danish nationwide registers, we conducted a matched case-control study...

  5. Frances Kelsey and Thalidomide in the US: A Case Study Relating to Pharmaceutical Regulations.

    Science.gov (United States)

    Seidman, Lisa A.; Warren, Noreen

    2002-01-01

    Presents a case study on the story of Dr. Frances Kelsey and the drug thalidomide, which was widely used in Europe for its therapeutic effects in the 1960s and later identified as having multiple effects on the body during development by the Food and Drug Administration (FDA). Describes the drug approval process in the United States and…

  6. History Places: A Case Study for Relational Database and Information Retrieval System Design

    Science.gov (United States)

    Hendry, David G.

    2007-01-01

    This article presents a project-based case study that was developed for students with diverse backgrounds and varied inclinations for engaging technical topics. The project, called History Places, requires that student teams develop a vision for a kind of digital library, propose a conceptual model, and use the model to derive a logical model and…

  7. The Implementation of IGE and Related Home-School-Community Relations Programs and Activities: Seven Case Studies. Theoretical Paper No. 64.

    Science.gov (United States)

    Miles, William R.; And Others

    Each of the seven case studies in this report describes the school and community, the implementation of Individually Guided Education (IGE) programs, and home-school-community relations programs and activities, and analyzes the home-school-community relations programs and activities. The selection of the seven schools was primarily based on the…

  8. Diet-related risk factors for leprosy: a case-control study.

    Directory of Open Access Journals (Sweden)

    Inge Wagenaar

    2015-05-01

    Full Text Available Food shortage was associated with leprosy in two recent studies investigating the relation between socioeconomic factors and leprosy. Inadequate intake of nutrients due to food shortage may affect the immune system and influence the progression of infection to clinical leprosy. We aimed to identify possible differences in dietary intake between recently diagnosed leprosy patients and control subjects.In a leprosy endemic area of Bangladesh, newly diagnosed leprosy patients and control subjects were interviewed about their socioeconomic situation, health and diet. Dietary intakes were recorded with a 24-hour recall, from which a Dietary Diversity Score (DDS was calculated. Body Mass Index (BMI was calculated and Household Food Insecurity Access Scale (HFIAS was filled out for every participant. Using logistic regression, a univariate, block wise multivariate, and an integrated analysis were carried out.52 leprosy cases and 100 control subjects were included. Food shortage was more common, dietary diversity was lower and household food insecurity was higher in the patient group. Patients consumed significantly less items from the DDS food groups 'Meat and fish' and 'Other fruits and vegetables.' Lower food expenditure per capita, lower BMI, lower DDS and absence of household food stocks are the main factors associated with an increased risk of having leprosy.Low income families have only little money to spend on food and consequently have a low intake of highly nutritious non-rice foods such as meat, fish, milk, eggs, fruits and vegetables. Development of clinical leprosy could be explained by deficiencies of the nutrients that these foods normally provide.

  9. Monitoring of urban growth and its related environmental impacts: Niamey case study

    Science.gov (United States)

    Perotti, Luigi; Tankari Dan-Badjo, Abdourahamane; De Luca, Domenico Antonio; Antonella Dino, Giovanna; Lasagna, Manuela; Spadafora, Francesco; Yadji, Guero; Konaté, Moussa

    2016-04-01

    The present contribution is about a preliminary study of the evolution of Niamey city (Niger) during last decades. Such research is part of an UNICOO project (funded by the University of Turin) and connected to the Edulink Cooperation Project (R.U.S.S.A.D.E.), a multidisciplinary project between Italy, Niger, Burkina Faso and Tchad funded on ACP- EU cooperation program in Higher Education. Recent advances in remote sensing, both in satellite hardware technology (i.e. image availability) and image processing algorithm development, provide opportunities for collection and analysis of multitemporal information on urban form and size that can be useful for policy and planning. In spite of these developments, there are also limitations to remote sensing and its application in practice. Some opportunities for, and limitations on, monitoring urban growth using remote sensing data are shown in the present contribution; moreover examples of environmental impacts of urban growth, as monitored with remote sensing, are provided. Niamey is the capital of Niger and is the first city in the country in size and economic importance. Its population increased gradually, from about 3,000 units in 1930 to about 30,000 in 1960, rising to 250,000 in 1980 and, according to estimates, to 800,000 units in 2000. Its patterns of population distribution, livelihoods, and its dominant role within the national economy of Niger make it a good representative case study for West Africa. This case study will consider the recent historical context of continued urban growth and will assess potential future impacts of settlement patterns. The rapid growth of Niamey in the last decades brought relative prosperity but it certainly affected patterns of land use within the city and the emerging urban system. After a preliminary sketch of the georesources in the city (qualitative and quantitative characterization of the surface water and groundwater, and of aggregates), an analyses of the urban growth and

  10. University Intervention into Community Issues as Dialogic Public Relations: A Case Study

    Science.gov (United States)

    Byrne, Jamie M.

    2007-01-01

    This paper examines a study of the wastewater collection and treatment issues of Little Rock and North Little Rock, Arkansas by University of Arkansas at Little Rock personnel and how it constitutes dialogic public relations. The paper defines dialogic public relations using Kent and Taylor's work and then uses their criteria to describe how this…

  11. Student experiences of virtual reality - a case study in learning special relativity

    CERN Document Server

    McGrath, D; McIntyre, T J; Savage, C M; Williamson, M

    2009-01-01

    We present a study of student learning through the use of virtual reality. A software package is used to introduce concepts of special relativity to students in a game-like environment where users experience the effects of travelling at near light speeds. From this new perspective, space and time are significantly different to that experienced in everyday life. The study explores how students have worked with this environment and how these students have used this experience in their study of special relativity. A mixed method approach has been taken to evaluate the outcomes of separate implementations of the package at two universities. Students found the simulation to be a positive learning experience and described the subject area as being less abstract after its use. Also, students were more capable of correctly answering concept questions relating to special relativity, and a small but measurable improvement was observed in the final exam.

  12. Geographical Indications and the Trade Related Property Rights Agreement: A Case Study of Basmati Rice Exports

    OpenAIRE

    2004-01-01

    The recent controversy over the granting of patenting rights to three new strains of Basmati rice by the US Patent and Trademark Office is used as a case study to analyze the impact of incomplete protection of intellectual property. Results suggest that there is evidence that the introduction of a competing product that may infringe on India's geographical indicator has harmed Indian producers in key export markets.

  13. Anorectal malformations and pregnancy-related disorders : a registry-based case-control study in 17 European regions

    NARCIS (Netherlands)

    Wijers, C. H. W.; van Rooij, I. A. L. M.; Bakker, M. K.; Marcelis, C. L. M.; Addor, M. C.; Barisic, I.; Beres, J.; Bianca, S.; Bianchi, F.; Calzolari, E.; Greenlees, R.; Lelong, N.; Latos-Bielenska, A.; Dias, C. M.; McDonnell, R.; Mullaney, C.; Nelen, V.; O'Mahony, M.; Queisser-Luft, A.; Rankin, J.; Zymak-Zakutnia, N.; de Blaauw, I.; Roeleveld, N.; de Walle, H. E. K.

    2013-01-01

    Objective To identify pregnancy-related risk factors for different manifestations of congenital anorectal malformations (ARMs). Design A population-based case-control study. Setting Seventeen EUROCAT (European Surveillance of Congenital Anomalies) registries, 1980-2008. Population The study populati

  14. Anorectal malformations and pregnancy-related disorders: a registry-based case-control study in 17 European regions

    NARCIS (Netherlands)

    Wijers, C.H.W.; Rooij, I.A.L.M. van; Bakker, M.K.; Marcelis, C.L.M.; Addor, M.C.; Barisic, I.; Beres, J.; Bianca, S.; Bianchi, F.; Calzolari, E.; Greenlees, R.; Lelong, N.; Latos-Bielenska, A.; Dias, C.M.; McDonnell, R.; Mullaney, C.; Nelen, V.; O'Mahony, M.; Queisser-Luft, A.; Rankin, J.; Zymak-Zakutnia, N.; Blaauw, I. de; Roeleveld, N.; Walle, H.E. de

    2013-01-01

    OBJECTIVE: To identify pregnancy-related risk factors for different manifestations of congenital anorectal malformations (ARMs). DESIGN: A population-based case-control study. SETTING: Seventeen EUROCAT (European Surveillance of Congenital Anomalies) registries, 1980-2008. POPULATION: The study popu

  15. Relation between Rural Financial Development and Rural Economic Growth: A Case Study of Yunnan Province

    Institute of Scientific and Technical Information of China (English)

    Lei; XU; Lijia; HU

    2015-01-01

    Rural economy is an essential part of China’s national economy. It is necessary to study mutual relation between rural financial development and rural economic growth. In this study,panel VAR model was built. Based on time series data in 1995- 2010,it tested the relation between rural financial development and rural economic growth through ADF test,co-integration test and Granger causality test. Finally,it came up with policy recommendations,in the hope of promoting coordinated development of rural finance and rural economy.

  16. Formal Food-related Networks in Ireland: A Case Study Analysis

    Directory of Open Access Journals (Sweden)

    Maeve Henchion

    2012-03-01

    Full Text Available  Strategic networking is of crucial importance for innovation in small and medium sized enterprises (SMEs as it enables these companies access external resources and overcome internal constraints. However, SMEs often lack the skills and competencies to engage in and benefit from networks. Consequently SMEs often fail in establishing strategic and efficient networks. To date, there is limited guidance available on the optimal design of such networks. Furthermore, limited guidance is available on the number of networks, and level of engagement therein, that companies should be involved with. Using case studies across a range of formal networks within the food sector in Ireland, insights into the success factors and barriers to network learning are presented, which provide a foundation for such guidelines. Three case studies were selected for analysis in Ireland. Up to ten in-depth interviews were scheduled with the network managers and key informants from the triple helix (i.e. policy, research and industry sectors within each formal network. Initially, interviewees were identified as a result of a review of secondary sources and personal knowledge of the authors. The snowball sampling technique was then employed to identify additional interviewees within each network. The findings from this study revealed that some formal networks had a strong institutional influence, including significant financial inputs, whilst others had bottom-up origins. Many networks had strong levels of interaction prior to formalisation, which provided solid trust-based foundations. Innovation and/or learning were not the expressed objectives of all networks at the outset. However, interviewees across all three networks felt that positive impacts had been achieved in these areas. Whilst being involved in a broad network can provide access to a wider range of ideas, these case studies suggest that being involved in a smaller, dense network, with high levels of IP

  17. Relational Understanding of the Derivative Concept through Mathematical Modeling: A Case Study

    Science.gov (United States)

    Sahin, Zulal; Aydogan Yenmez, Arzu; Erbas, Ayhan Kursat

    2015-01-01

    The purpose of this study was to investigate three second-year graduate students' awareness and understanding of the relationships among the "big ideas" that underlie the concept of derivative through modeling tasks and Skemp's distinction between relational and instrumental understanding. The modeling tasks consisting of warm-up,…

  18. A cross-sectional epidemiological study of domestic animals related to human leptospirosis cases in Nicaragua.

    Science.gov (United States)

    Flores, Byron J; Pérez-Sánchez, Tania; Fuertes, Héctor; Sheleby-Elías, Jessica; Múzquiz, José Luis; Jirón, William; Duttmann, Christianne; Halaihel, Nabil

    2017-02-28

    Leptospirosis is one of the most extended zoonosis worldwide and humans become infected most commonly through contact with the urine of carrier animals, either directly or via contaminated water or soil. The aim in this study was to analyse the epidemiological behaviour of Leptospira spp., from domestic animals around the sites of human leptospirosis cases in Nicaragua, from 2007 through 2013. We report the results of a cross-sectional epidemiological study with a non-probability sampling of blood (n=3050) and urine (n=299) from Domestic Animals (DA) around the sites of human leptospirosis cases in Nicaragua. We analysed data obtained through Microscopic Agglutination Test (MAT), in-vitro culture, real time PCR and sequencing of lfb1 locus. Frequencies of 30.31% (95% CI: 28.66-31.95) and 15.38% (95% CI: 11.12-19.64) were obtained from serological test and from in-vitro culture, respectively. Although similar frequencies from serology test (P≥0.05) were found in DA species, in-vitro culture frequencies were significantly higher from bovine, equine and sheep (PLeptospira spp. were encountered, with the highest presence of Icterohaemorrhagiae serogroup 34.65% (95% CI: 29.35-39.94). We identified 7 samples homologous to L. interrogans species Pyrogenes serovar and 3 samples as L. noguchii Louisiana or Panama serovars by analysis of lfb1 sequences. We were able to establish a temporal and spatial correlation from DA and cumulative incidence of human cases. Therefore an effective epidemiological surveillance should be implemented with a specific control program toward DA in order to reduce human leptospirosis incidence.

  19. A case-control study of plasma antioxidant (pro-)vitamins in relation to respiratory symptoms in non-smokers

    NARCIS (Netherlands)

    Grievink, L.; Smit, H.A.; Veer, van 't P.; Brunekreef, B.; Kromhout, D.

    2000-01-01

    The aim of this study was to investigate the relations between plasma levels of antioxidants, [beta]-carotene and [alpha]-tocopherol, and chronic respiratory symptoms in Dutch adults who never smoked or were long-term former smokers. Cases (who reported one or more respiratory symptoms) and controls

  20. RESPONSE TO THE RICHARD ERSKINES ARTICLE RELATIONAL HEALING OF EARLY AFFECT-CONFUSION - PART 3 OF A CASE STUDY TRILOGY

    Directory of Open Access Journals (Sweden)

    Maša Žvelc

    2013-10-01

    Full Text Available This article provides four responses from senior psychotherapists and supervisors to Erskine’s articleRelational Healing of Early Affect-Confusion. The authors approach the third part of case study trilogy from their particular perspective and provide both challenge and respect for the author’s work.

  1. A case study of the relation between energetic electrons and magnetic activity

    Science.gov (United States)

    Lam, Hing-Lan

    The case study is based on the event of Telesat Canada's Anik E-1 and E-2 satellite failures on two consecutive days of January 20 and 21 in 1994. The malfunction of the two satellites wreaked havoc with television and computer data transmissions across Canada, as well as telephone services to remote northern communities. The fluxes of ∼2 MeV energetic electrons were high prior to the occurrences of the two Anik E satellite upsets. In this study, energetic electron fluxes were checked against magnetic activity. Strong Pc5 magnetic pulsations in the ground magnetic fluctuations were found to be present during periods of high electron fluxes, lending support to the contention of Pc5 ULF waves as a mechanism for energetic electron flux enhancement.

  2. A case study on relation between roughness, lubrication and fatigue life of rolling bearings

    Science.gov (United States)

    Balan, M. R.; Tufescu, A.; Cretu, S. S.

    2016-08-01

    A spherical roller bearing under high radial loading, constant speed and imposed roughness for the contacting surfaces was chosen as case study. Different lubrication regimes were obtained by varying oil viscosity through the operating temperature. For bearings with especially machined contacting surfaces, λ-ratio is firstly determined and its value is used to estimate the particular value of the lubrication parameter κ. Using the λ-ratio approach the paper reveals the relationship between roughness amplitude and the modified rating life of rolling bearings. The roughness values corresponding to good manufacturing practice are possible to be determined for each particular case. Three groups of random Gaussian roughness were generated with the same values for the Ra parameter as used in the modified lives investigations. For medium and especially high radial loads, the contacts between rough surfaces develop, inside the shallow layer, von Mises equivalent stresses higher than the fatigue limit stress. For condition of lack of lubricant or starved lubrication, these findings explain the initiation of the rolling contact fatigue in the shallow layer, close to contacting surfaces.

  3. Contextual Mobile Learning Strongly Related to Industrial Activities: Principles and Case Study

    CERN Document Server

    David, Bertrand; Chalon, René

    2010-01-01

    M-learning (mobile learning) can take various forms. We are interested in contextualized M-learning, i.e. the training related to the situation physically or logically localized. Contextualization and pervasivity are important aspects of our approach. We propose in particular MOCOCO principles (Mobility - COntextualisation - COoperation) using IMERA platform (Mobile Interaction in the Augmented Real Environment). We are studying various mobile learning contexts related to professional activities, in order to master appliances (Installation, Use, Breakdown diagnostic and Repairing). Contextualization, traceability and checking of execution of prescribed operations are based mainly on the use of RFID labels. Investigation of the appropriate training methods for this kind of learning situation, applying mainly a constructivist approach known as "Just-in-time learning", "learning by doing", "learning and doing", constitutes an important topic of this project. From an organizational point of view we are in perfect...

  4. Time-related patient data retrieval for the case studies from the pharmacogenomics research network.

    Science.gov (United States)

    Zhu, Qian; Tao, Cui; Ding, Ying; Chute, Christopher G

    2012-11-01

    There are lots of question-based data elements from the pharmacogenomics research network (PGRN) studies. Many data elements contain temporal information. To semantically represent these elements so that they can be machine processiable is a challenging problem for the following reasons: (1) the designers of these studies usually do not have the knowledge of any computer modeling and query languages, so that the original data elements usually are represented in spreadsheets in human languages; and (2) the time aspects in these data elements can be too complex to be represented faithfully in a machine-understandable way. In this paper, we introduce our efforts on representing these data elements using semantic web technologies. We have developed an ontology, CNTRO, for representing clinical events and their temporal relations in the web ontology language (OWL). Here we use CNTRO to represent the time aspects in the data elements. We have evaluated 720 time-related data elements from PGRN studies. We adapted and extended the knowledge representation requirements for EliXR-TIME to categorize our data elements. A CNTRO-based SPARQL query builder has been developed to customize users' own SPARQL queries for each knowledge representation requirement. The SPARQL query builder has been evaluated with a simulated EHR triple store to ensure its functionalities.

  5. Hippocampus age-related microstructural changes in schizophrenia: a case-control mean diffusivity study.

    Science.gov (United States)

    Chiapponi, Chiara; Piras, Fabrizio; Fagioli, Sabrina; Girardi, Paolo; Caltagirone, Carlo; Spalletta, Gianfranco

    2014-08-01

    Macrostructural-volumetric abnormalities of the hippocampus have been described in schizophrenia. Here, we characterized age-related changes of hippocampal mean diffusivity as an index of microstructural damage by carrying out a neuroimaging study in 85 patients with a DSM-IV-TR diagnosis of schizophrenia and 85 age- and gender-matched healthy controls. We performed analyses of covariance, with diagnosis as fixed factor, mean diffusivity as dependent variable and age as covariate. Patients showed an early increase in mean diffusivity in the right and left hippocampus that increased with age. Thus, microstructural hippocampal changes associated with schizophrenia cannot be confined to a specific time window.

  6. Serum Chemerin Levels in relation to Osteoporosis and Bone Mineral Density: A Case-Control Study

    Directory of Open Access Journals (Sweden)

    Jing He

    2015-01-01

    Full Text Available Background. To evaluate serum chemerin levels in patients with osteoporosis and healthy controls and to investigate the relationship between serum chemerin levels and bone mineral density (BMD. Methods. An age- and gender-matched case-control study was conducted. Pearson’s correlation test was performed to investigate the relationship between serum chemerin levels and BMD. Results. There were 93 patients included in the osteoporosis group and 93 matched controls. Serum chemerin level was significantly higher in patients with osteoporosis (87.27±5.80 ng/mL than patients in control (71.13±5.12 ng/mL (P<0.01. There was a negative correlation between femoral bone mineral density and chemerin in both groups (R=-0.395, P<0.01 in osteoporosis group; R=-0.680, P<0.01 in control and also a negative correlation between lumbar bone mineral density with chemerin in both groups (R=-0.306, P<0.01 in osteoporosis group; R=-0.362, P<0.01 in control. Conclusions. Patients with osteoporosis presented a higher level of serum chemerin, which witnessed an inverse correlation with BMD. Further studies are needed to explore the role of chemerin in the pathophysiology of osteoporosis.

  7. Building a Mien-American house: A case study in school-community relations

    Science.gov (United States)

    Hammond, Lorie A.

    2000-10-01

    Researchers and policymakers agree that schools and parents must work together if they are to provide the sustenance, services, and support which children need to be successful in our increasingly complex society. (Clark, 1983; Comer, 1980, 1996; Clinton, 1995; Epstein, 1995, 1996). Unfortunately, the social and academic success of language minority students is often adversely affected by the alienation of parents from school culture and by the "deficit" view which teachers hold of language minority parents' academic and parenting skills (Boggs, 1985; Delgado-Gaitan, 1990; Heath, 1983; Lareau, 1987, 1989; Philips, 1983). This case study describes the attempts of one school site to build academic and social bridges between immigrant families from a Southeast Asian Hill Tribe, the Iu Mien, and a mainstream elementary school. This effort is facilitated by a constructivist approach to curriculum in which parents, teachers, and children create an intercultural space---a school community garden---as a context in which academic dialogue can occur. Various strategies which enable inter-cultural learning are described, including the use of students as ethnographers, of parents as expert teachers, and of teachers as cultural brokers. The study also considers the cultural conflicts and understandings which occurred when American teachers and Mien parents built a Mien field-house together: a structure which became symbolic of their blended lives. Through both a descriptive narration and interviews with various participants, the study analyzes (a) community-based curriculum development, led by practitioner reformers, as a way to enable language minority students to be academically successful within their own life worlds, as well as (b) the political and bureaucratic forces which make community-based reforms difficult to sustain. This study employs qualitative research strategies within an action-research context in which the author plays the dual role of practitioner reformer

  8. Polybrominated diphenyl ethers in relation to autism and developmental delay: a case-control study

    Directory of Open Access Journals (Sweden)

    Pessah Isaac

    2011-01-01

    Full Text Available Abstract Background Polybrominated diphenyl ethers (PBDEs are flame retardants used widely and in increasing amounts in the U.S. over the last few decades. PBDEs and their metabolites cross the placenta and studies in rodents demonstrate neurodevelopmental toxicity from prenatal exposures. PBDE exposures occur both via breastfeeding and hand-to-mouth activities in small children. Methods Participants were 100 children from the CHARGE (CHildhood Autism Risk from Genetics and the Environment Study, a case-control epidemiologic investigation of children with autism/autism spectrum disorder, with developmental delay and from the general population. Diagnoses of autism were confirmed by the Autism Diagnostic Observation Schedule and Autism Diagnostic Inventory-Revised, and of developmental delay using the Mullen's Scales of Early Learning and the Vineland Adaptive Behavior Scales. Typically developing controls were those with no evidence of delay, autism, or autism spectrum disorder. Eleven PBDE congeners were measured by gas chromatography/mass spectrometry from serum specimens collected after children were assessed. Logistic regression was used to evaluate the association between plasma PBDEs and autism. Results Children with autism/autism spectrum disorder and developmental delay were similar to typically developing controls for all PBDE congeners, but levels were high for all three groups. Conclusions Plasma samples collected post-diagnosis in this study may not represent early life exposures due to changes in diet and introduction of new household products containing PBDEs. Studies with direct measurements of prenatal or infant exposures are needed to assess the possible causal role for these compounds in autism spectrum disorders.

  9. Community relations and child-led microfinance: a case study of caregiving children in Kenya.

    Science.gov (United States)

    Skovdal, Morten

    2010-01-01

    Rampant levels of AIDS and poverty have made many children in sub-Saharan Africa the primary caregivers of their ageing or ailing guardians. This paper reports on a social action fund initiative that brought caregiving children together to set-up and run income generating activities as a group with the aim of strengthening their coping capabilities. To further our understanding of child-led microfinance activities, this paper explores how intra-community relations can both facilitate and undermine child-led activities, and how these activities in turn can further strengthen some intra-community relations. Twenty-one children (aged 12-17) and six guardians participated in this study. Data included draw-and-write compositions (n=21), essays (n=16), workshop notes and proposals (n=8) and in-depth interviews (n=16). A thematic analysis revealed that the children actively drew on the expertise and involvement of some guardians in the project as well as on each other, developing supportive peer relations that helped strengthen their coping capabilities. However, the children's disenfranchised position in the community meant that some adults took advantage of the child-led activities for their own personal gain. Some children also showed a lack of commitment to collective work, undermining the morale of their more active peers. Nevertheless, both guardians and the children themselves began to look at caregiving children differently as their engagement in the project began to earn them respect from the community - changing guardian/child relations. The paper concludes that microfinance interventions targeting children and young people must consider children's relationships with each other and with adults as key determinants of Project success.

  10. Quality Service and its Relation with Global Satisfaction in Fast Food Consumers. A Case Study

    Directory of Open Access Journals (Sweden)

    Luis Enrique IBARRA MORALES

    2015-08-01

    Full Text Available The present study analyzes the quality service perception and its relation with the satisfaction for the fast food consumers of hamburgers’ sector of the chain Burger King in Hermosillo, Sonora. By the application of Servperf of Cronin and Taylor methodology and a data regression method, through the coefficient of determination (R2 was determined that the independent variables explain the variability or variance of 82.9% in consumer satisfaction and that the explanatory variable which has the most influence in absolute value over the explained variable is reliability, due to its standardized beta is 0.301, being the highest score among the variables. To achieve the objective of this study, a quantitative and correlation investigation was designed, where data was collected from a survey structured by five dimensions, measured by 22 items. It was applied to a random and representative sample of 385 consumers, with a 95% level confidence and a ±5% of permissible error. An inferential statistical analysis allowed observing a positive relation between consumers’ satisfaction level and quality service. The results showed that Servperf is a valid instrument with psychometric characteristics of high reliability that makes it appropriate to measure quality service. The same way, it was observed an index of service global satisfaction of 69.27%, which according to the scale used implies clients are satisfied with the received service.

  11. Health related quality of life may increase when patients with a stoma attend patient education - a case-control study

    DEFF Research Database (Denmark)

    Danielsen, Anne Kjaergaard; Rosenberg, Jacob

    2014-01-01

    included 50 patients in the study. Health related quality of life was measured before hospital discharge, three months and six months after stoma creation. The program included educational interventions involving lay-teachers, alongside health professional teachers. RESULTS: We found a significant rise......INTRODUCTION: Adaptation to living with a stoma is complex, and studies have shown that stoma creation has a great impact on patients' health related quality of life. The objective was to explore the effect of a structured patient education program on health related quality of life. Therefore, we...... implemented interventions aimed at increasing health related quality of life during and after hospital admission. MATERIALS AND METHODS: We designed a case/control study aimed at adult patients admitted to the surgical ward for stoma creation, irrespective of type of stoma or reason for creation of stoma. We...

  12. A 3 year case study of alcohol related psychotic disorders at Hospital Seremban.

    Science.gov (United States)

    George, S; Chin, C N

    1998-09-01

    This paper reports the characteristics and psychopathology of alcohol dependents with alcohol induced psychotic disorder admitted to the Seremban Hospital. The method is that of a case study of all alcohol dependents with alcohol induced psychotic disorder admitted to the Psychiatric Ward, Hospital Seremban over 3 years (1993-1995). There were 34 subjects, 30 Indians, 3 Chinese and 1 Malay with a mean age of 43 years. 32 were men and predominantly of Social Class IV and V (91%). They had a mean duration of drinking of 14.2 years and had a mean weekly consumption of 69.5 units of alcohol. There was a family history of alcohol dependence in (44%). The majority (68%) consumed samsu with beer the second choice. Auditory hallucinations (26) and delusions (16) were common while visual hallucinations (3) and depression (2) were less frequent. Speech disorder occurred in 4 subjects. 2 developed delirium tremens and 1 died. Liver function test was normal in 55%. All except the death from delirium tremens responded to treatment with a combination of anxiolytics, thiamine and antipsychotics and were rapidly discharged. The mean stay was 7 days. However, (68%) did not return for follow up and only 4 were abstinent from alcohol at the time of follow up.

  13. Travel-related venous thrombosis: results from a large population-based case control study (MEGA study.

    Directory of Open Access Journals (Sweden)

    Suzanne C Cannegieter

    2006-08-01

    Full Text Available BACKGROUND: Recent studies have indicated an increased risk of venous thrombosis after air travel. Nevertheless, questions on the magnitude of risk, the underlying mechanism, and modifying factors remain unanswered. METHODS AND FINDINGS: We studied the effect of various modes and duration of travel on the risk of venous thrombosis in a large ongoing case-control study on risk factors for venous thrombosis in an unselected population (MEGA study. We also assessed the combined effect of travel and prothrombotic mutations, body mass index, height, and oral contraceptive use. Since March 1999, consecutive patients younger than 70 y with a first venous thrombosis have been invited to participate in the study, with their partners serving as matched control individuals. Information has been collected on acquired and genetic risk factors for venous thrombosis. Of 1,906 patients, 233 had traveled for more than 4 h in the 8 wk preceding the event. Traveling in general was found to increase the risk of venous thrombosis 2-fold (odds ratio [OR] 2.1; 95% confidence interval [CI] 1.5-3.0. The risk of flying was similar to the risks of traveling by car, bus, or train. The risk was highest in the first week after traveling. Travel by car, bus, or train led to a high relative risk of thrombosis in individuals with factor V Leiden (OR 8.1; 95% CI 2.7-24.7, in those who had a body mass index of more than 30 kg/m(2 (OR 9.9; 95% CI 3.6-27.6, in those who were more than 1.90 m tall (OR 4.7; 95% CI 1.4-15.4, and in those who used oral contraceptives (estimated OR > 20. For air travel these synergistic findings were more apparent, while people shorter than 1.60 m had an increased risk of thrombosis after air travel (OR 4.9; 95% CI 0.9-25.6 as well. CONCLUSIONS: The risk of venous thrombosis after travel is moderately increased for all modes of travel. Subgroups exist in which the risk is highly increased.

  14. Caregiver-related predictors of thermal burn injuries among Iranian children: A case-control study

    Science.gov (United States)

    Sadeghi-Bazargani, Homayoun; Mohammadi, Reza; Ayubi, Erfan; Almasi-Hashiani, Amir; Pakzad, Reza; Sullman, Mark J. M.; Safiri, Saeid

    2017-01-01

    Purpose Burns are a common and preventable cause of injury in children. The aim of this study was to investigate child and caregiver characteristics which may predict childhood burn injuries among Iranian children and to examine whether confounding exists among these predictors. Methods A hospital based case-control study was conducted using 281 burn victims and 273 hospital-based controls, which were matched by age, gender and place of residence (rural/urban). The characteristics of the children and their caregivers were analyzed using crude and adjusted models to test whether these were predictors of childhood burn injuries. Results The age of the caregiver was significantly lower for burn victims than for the controls (Pcaregiver spent outdoors with the child and their economic status had a significant positive association with the odds of a burn injury (Pcaregivers was independently associated with the child's odds of suffering a burn injury (OR = 1.12, 95% CI: 1.04–1.21). The research also found that children with ADHD (Inattentive subscale: Crude OR = 2.14, 95% CI: 1.16–3.95, Adjusted OR = 5.65, 95% CI: 2.53–12.61; Hyperactive subscale: Crude OR = 1.73, 95% CI: 1.23–2.41, Adjusted OR = 2.53, 95% CI: 1.65–3.87) also had increased odds of suffering a burn injury. However, several variables were identified as possible negative confounder variables, as the associations were stronger in the multivariate model than in the crude models. Conclusion The caregiver's characteristics which were predictors of burn injuries among Iranian children were: being younger, high socio-economic status, Type A behavioural pattern and spending more time outdoors. In addition, the relationship between a child's ADHD scores and the odds of a burn injury may be negatively confounded by the caregivers predictor variables. PMID:28151942

  15. Dynamics of tremor-related oscillations in the human globus pallidus: A single case study

    Science.gov (United States)

    Hurtado, José M.; Gray, Charles M.; Tamas, Laszlo B.; Sigvardt, Karen A.

    1999-01-01

    Physiological evidence indicates that the resting tremor of Parkinson’s disease originates in oscillatory neural activity in the forebrain, but it is unknown whether that activity is globally synchronized or consists of parallel, independently oscillating circuits. In the present study, we used dual microelectrodes to record tremor-related neuronal activity from eight sites in the internal segment of the globus pallidus (GPi) from an awake Parkinson’s disease patient undergoing stereotaxic pallidotomy. We utilized spectral analysis to evaluate the temporal correlations between multiunit activity at spatially separated sites and between neural and limb electromyographic activity. We observed that some GPi neural pairs oscillated synchronously at the tremor frequency, whereas other neural pairs oscillated independently. Additionally, we found that GPi tremor-related activity at a given site could fluctuate between states of synchronization and independence with respect to upper limb tremor. Consistent with this finding, some paired recording sites within GPi showed periods of transient synchronization. These observations support the hypothesis of independent tremor-generating circuits whose coupling can fluctuate over time. PMID:9990083

  16. Benchmarking the DFT methodology for assessing antioxidant-related properties: quercetin and edaravone as case studies.

    Science.gov (United States)

    La Rocca, Mario Vincenzo; Rutkowski, Malvina; Ringeissen, Stéphanie; Gomar, Jérôme; Frantz, Marie-Céline; Ngom, Saliou; Adamo, Carlo

    2016-10-01

    The overall objective was to identify an accurate computational electronic method to virtually screen phenolic compounds through their antioxidant and free-radical scavenging activity. The impact of a key parameter of the density functional theory (DFT) approach was studied. Performances of the 21 most commonly used exchange-correlation functionals are thus detailed in the evaluation of the main energetic parameters related to the activities of two prototype antioxidants, namely quercetin and edaravone, is reported. These functionals have been chosen among those belonging to three different families of hybrid functionals, namely global, range separated, and double hybrids. Other computational parameters have also been considered, such as basis set and solvent effects. The selected parameters, namely bond dissociation enthalpy (BDE), ionization potential (IP), and proton dissociation enthalpy (PDE) allow a mechanistic evaluation of the antioxidant activities of free radical scavengers. Our results show that all the selected functionals provide a coherent picture of these properties, predicting the same order of BDEs and PDEs. However, with respect to the reference values, the errors found at CBS-Q3 level significantly vary with the functional. Although it is difficult to evidence a global trend from the reported data, it clearly appears that LC-ωPBE, M05-2X, and M06-2X are the most suitable approaches for the considered properties, giving the lowest cumulative mean absolute errors. These methods are therefore suggested for an accurate and fast evaluation of energetic parameters related to an antioxidant activity via free radical scavenging.

  17. Association of dental and periodontal status with bisphosphonate-related osteonecrosis of the jaws. A retrospective case controlled study

    OpenAIRE

    Kos, Marcin

    2014-01-01

    Introduction To assess the association of oral hygiene, dental caries, and periodontal status with bisphosphonate-related osteonecrosis of the jaws. Material and methods A retrospective case-control study on 81 patients treated for neoplasms with bone metastases. Twenty-nine patients with bone necrosis and 52 controls treated with bisphosphonates were compared using the Oral Hygiene Index, Decay, Missing, Filled Teeth, Community Periodontal Index of Treatment Needs, and Residual Periodontal B...

  18. An intervention program related to reading development – a case study of a child with Williams syndrome

    OpenAIRE

    Alevriadou, Anastasia; Griva, Elena; Massi, Maria

    2013-01-01

    The present paper is related to a case study of an 8-year-old girl with Williams syndrome and mild intellectual disability. Initial informal assessments and standardized tests indicated that her reading ability was underdeveloped, as well as her phonological awareness. Hence, an intervention for the development of reading skills was designed according to the principles of the ‘top-down’ educational model, combining features from several teaching methods, such as ‘holistic approach’, ‘holistic...

  19. Retrieval of Legal Information Through Discovery Layers: A Case Study Related to Indian Law Libraries

    Directory of Open Access Journals (Sweden)

    Kushwah, Shivpal Singh

    2016-09-01

    Full Text Available Purpose. The purpose of this paper is to analyze and evaluate discovery layer search tools for retrieval of legal information in Indian law libraries. This paper covers current practices in legal information retrieval with special reference to Indian academic law libraries, and analyses its importance in the domain of law.Design/Methodology/Approach. A web survey and observational study method are used to collect the data. Data related to the discovery tools were collected using email and further discussion held with the discovery layer/ tool /product developers and their representatives.Findings. Results show that most of the Indian law libraries are subscribing to bundles of legal information resources such as Hein Online, JSTOR, LexisNexis Academic, Manupatra, Westlaw India, SCC web, AIR Online (CDROM, and so on. International legal and academic resources are compatible with discovery tools because they support various standards related to online publishing and dissemination such as OAI/PMH, Open URL, MARC21, and Z39.50, but Indian legal resources such as Manupatra, Air, and SCC are not compatible with the discovery layers. The central index is one of the important components in a discovery search interface, and discovery layer services/tools could be useful for Indian law libraries also if they can include multiple legal and academic resources in their central index. But present practices and observations reveal that discovery layers are not providing facility to cover legal information resources. Therefore, in the present form, discovery tools are not very useful; they are an incomplete and half solution for Indian libraries because all available Indian legal resources available in the law libraries are not covered.Originality/Value. Very limited research or published literature is available in the area of discovery layers and their compatibility with legal information resources.

  20. Virtual water trade patterns in relation to environmental and socioeconomic factors: a case study for Tunisia

    Science.gov (United States)

    Chouchane, Hatem; Krol, Maarten; Hoekstra, Arjen

    2016-04-01

    Water scarcity is among the main problems faced by many societies. Growing water demands put increasing pressure on local water resources, especially in water-short countries. Virtual water trade can play a key role in filling the gap between local demands and supply. This study aims to analyze the changes in virtual water trade of Tunisia in relation to environmental and socio-economic factors such as GDP, irrigated land, precipitation, population and water scarcity. The water footprint is estimated using Aquacrop for six crops over the period 1981-2010 at daily basis and a spatial resolution of 5 by 5 arc minutes. Virtual water trade is quantified at yearly basis. Regression models are used to investigate changes in virtual water trade in relation to various environmental and socio-economic factors. The explaining variables are selected in order to help understanding the trend and the inter-annual variability of the net virtual water import; GDP, population and irrigated land are hypothesized to explain the trend, and precipitation and water scarcity to explain variability. The selected crops are divided into three baskets. The first basket includes the two most imported crops, which are mainly rain-fed (wheat and barley). The second basket contains the two most exported crops, which are both irrigated and rain-fed (olives and dates). In the last basket we find the two highest economic blue water productive crops, which are mainly irrigated (tomatoes and potatoes). The results show the impact of each factor on net virtual water import of the selected crops during the period 1981-2010. Keywords: Virtual water, trade patterns, Aquacrop, Tunisia, water scarcity, water footprint.

  1. Prospective study of asbestos-related diseases incidence cases in primary health care in an area of Barcelona province

    Science.gov (United States)

    2010-01-01

    Background Asbestos related diseases include a number of conditions due to inhalation of asbestos fibres at work, at home or in the environment, such as pleural mesothelioma, asbestosis and calcified pleural plaques. Few epidemiological studies have established the incidence of asbestos related diseases in our area. The present proposal is based on a retrospective study externally funded in 2005 that is currently taking place in the same area and largely carried out by the same research team. The aim of the study is to achieve a comprehensive and coordinated detection of all new cases of Asbestos Related Diseases presenting to primary care practitioners. Methods/design This is a multicentre, multidisciplinary and pluri-institutional prospective study. Setting 12 municipalities in the Barcelona province within the catchment area of the health facilities that participate in the study. Sample This is a population based study, of all patients presenting with diseases caused by asbestos in the study area. Measurements A clinical and epidemiological questionnaire will be filled in by the trained researchers after interviewing the patients and examining their clinical reports. Discussion Data on the incidence of the different Asbestos Related Diseases in this area will be obtained and the most plausible exposure source and space-time-patient profile will be described. The study will also improve the standardization of patient management, the coordination between health care institutions and the development of preventive activities related with asbestos exposure and disease. PMID:20412567

  2. ASPECTUAL INFLUENCE ON TEMPORAL RELATIONS: A CASE STUDY OF THE EXPERIENTIAL GUO IN MANDARINE

    Directory of Open Access Journals (Sweden)

    Jiun-Shiung Wu

    2009-12-01

    Full Text Available This paper examines how the temporal relation between a clause containing the experiential guo and an adjacent clause is determined. Mandarin is a language not morphologically marked for tenses (e.g., Lin 2006, and therefore, tenses cannot help in determining temporal relations in Mandarin. However, Mandarin has a rich aspectual system. This paper argues that the experiential guo indirectly influences temporal relations via rhetorical relations by either specifying a default rhetorical relation, or by constraining the circumstances under which a certain rhetorical relation can connect a clause with guo to an adjacent clause. This paper also argues that the default rhetorical relation and the constraints are determined by the aspectual properties of the experiential marker. Other information, such as discourse connectors, lexical information, etc., can override the default rhetorical relation indicated by guo and specifies a rhetorical relation. Therefore, this paper concludes that in Mandarin aspect markers can indirectly affect temporal relations by means of rhetorical relations, a result consistent with Wu’s (2005b paper on the perfective marker le in Mandarin, and Wu’s (2007b, 2004 work on the progressive marker zai and the durative marker zhe.

  3. The Reporting Quality of Acupuncture-Related Infections in Korean Literature: A Systematic Review of Case Studies.

    Science.gov (United States)

    Kim, Tae-Hun; Kang, Jung Won; Park, Wan-Soo

    2015-01-01

    Objective. Acupuncture is generally accepted as a safe intervention when it is administered in appropriate clinical setting by well-educated and experienced practitioners. In this study, we reviewed observational studies on adverse events (AEs) or complications relevant to acupuncture practice in Korean literature for assessing their reporting quality and suggested recommendations for future ones on acupuncture-related infections. Method. Electronic databases including Medline, Embase, Cochrane library, Korean studies Information Service System, DBpia, National Digital Science Library, and Korean National Assembly Library were searched until May 2015. Combination of keywords including "acupuncture" and "infection" were used for searching databases. Result. A total of 23 studies from 2,739 literature articles were identified from electronic database searching until May 2015. From this review, we found that most case studies did not report enough information for judging causality between acupuncture and the AEs (or complications) as well as appropriateness of the acupuncture practice. In addition, acupuncture experts rarely participated in the reporting of these AEs (or complications). Conclusion. Based on these limitations, we suggest a tentative recommendation for future case studies on acupuncture-related infection. We hope that this recommendation would contribute to the improvement of the reporting quality of acupuncture-related AEs (or complications) in the future.

  4. Case Study: Testing with Case Studies

    Science.gov (United States)

    Herreid, Clyde Freeman

    2015-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses using case studies to test for knowledge or lessons learned.

  5. Canadian Civil-Military Relations, 1939-1941: A Case Study in Strategic Dialogue

    Science.gov (United States)

    2011-07-01

    relation constitutionnelle avec la Grande- Bretagne , de l’importance grandissante des États-Unis et des bouleversements dans la géopolitique occidentale...nouvelle relation constitutionnelle avec la Grande- Bretagne , de l’importance grandissante des États-Unis et des bouleversements dans la géopolitique

  6. Alumni Relations in Chinese HEIs: Case Studies of Three Major Universities

    Science.gov (United States)

    Zhimin, Luo; Chunlian, Chen; Xian, Wang

    2016-01-01

    Good alumni relations are key to universities and colleges winning support from their graduates. With reference to social capital theory, an important problem in establishing strong alumni relations is how to turn alumni resources, an important university social network, into productive, public, and abundant capital. Based on the established…

  7. Treachery by Any Other Name: A Case Study of the Toshiba Public Relations Crisis.

    Science.gov (United States)

    Hobbs, Jeffrey D.

    1995-01-01

    Explains that the battle to protect a corporation's image is critical during a crisis. Examines Toshiba's decision to sell weapons technology to the Soviet Union. Relates how the concept of "apologia" was used for insight into Toshiba's handling of the crisis. Argues that public relations in an image crisis is a battle for…

  8. National Technology Standards for K-12 Schools: A Case Study of Unresolved Issues in Public Relations

    Science.gov (United States)

    Mullen, Carol A.; Kealy, William A.; Sullivan, Ashley

    2004-01-01

    This article addresses an important need--the dissemination of information relating to technology as a public relations tool--and the associated exigency for administrator and teacher technology training. Specifically, we identify the increased expectations for the performance of school leaders and teachers, as well as unresolved issues in public…

  9. Levels of prolactin in relation to coagulation factors and risk of venous thrombosis. Results of a large population-based case-control study (MEGA-study)

    NARCIS (Netherlands)

    Stuijver, D.J.; Debeij, J.; Zaane, B. van; Dekkers, O.M.; Smit, J.W.A.; Buller, H.R.; Rosendaal, F.R.; Gerdes, V.E.; Cannegieter, S.C.

    2012-01-01

    The pituitary hormone prolactin is thought to influence coagulation. We aimed to study the relation between prolactin levels, coagulation factors and risk of venous thrombosis (VT). We used data from a large population based case-control study into aetiology of first VT (MEGA-study). Prolactin level

  10. Relations between rainfall and triggering of debris-flow: case study of Cancia (Dolomites, Northeastern Italy

    Directory of Open Access Journals (Sweden)

    M. Bacchini

    2003-01-01

    Full Text Available Debris-flows occurring in the area of Cancia (Dolomites, Northeastern Italy in recent years have exposed the population to serious risk. In response to the recurring hazard, an alarm and monitoring system was installed to provide a sufficient level of safeguard for inhabitants and infrastructures. The data recorded at three rain gauges during debris-flow events has been analysed, taking into consideration the different elevation of the gauges to delineate the storm rainfall distributions. Rainfall data is compared with the occurrence of debris-flows to examine relations between debris-flow initiation and rainfall. In addition, the data is compared with that recorded during debris-flows which occurred under similar or different geological settings in the Eastern Italian Alps, in order to define triggering thresholds. A threshold for debris-flow activity in terms of mean intensity, duration and mean annual precipitation (M.A.P. is defined for the study area The normalised rainfall and the normalised intensity are expressed as a per cent with respect to M.A.P. This threshold is compared with thresholds proposed by other authors, and the comparison shows that a lower value is obtained, indicating the debris-flow susceptibility of the area. The threshold equations are:  R/M.A.P. = - 1.36 · ln(I + 3.93  where I > 2 mm/h  I /M.A.P. = 0.74 · D-0.56.  The determination of a debris-flow threshold is linked to the necessity of a fast decisional phase in a warning system for debris-flow protection. This threshold cannot be used as a predictive tool, but rather as a warning signal for technicians who manage the monitoring/warning system.

  11. Membranous Nephropathy Associated With Immunological Disorder-Related Liver Disease: A Retrospective Study of 10 Cases.

    Science.gov (United States)

    Dauvergne, Maxime; Moktefi, Anissa; Rabant, Marion; Vigneau, Cécile; Kofman, Tomek; Burtey, Stephane; Corpechot, Christophe; Stehlé, Thomas; Desvaux, Dominique; Rioux-Leclercq, Nathalie; Rouvier, Philippe; Knebelmann, Bertrand; Boffa, Jean-Jacques; Frouget, Thierry; Daugas, Eric; Jablonski, Mathieu; Dahan, Karine; Brocheriou, Isabelle; Remy, Philippe; Grimbert, Philippe; Lang, Philippe; Chazouilleres, Oliver; Sahali, Dil; Audard, Vincent

    2015-07-01

    The association between membranous nephropathy (MN) and immunological disorder-related liver disease has not been extensively investigated, and the specific features of this uncommon association, if any, remain to be determined.We retrospectively identified 10 patients with this association. We aimed to describe the clinical, biological, and pathological characteristics of these patients and their therapeutic management. The possible involvement of the phospholipase A2 receptor (PLA2R) in these apparent secondary forms of MN was assessed by immunohistochemistry with renal and liver biopsy specimens.The mean delay between MN and liver disease diagnoses was 3.9 years and the interval between the diagnosis of the glomerular and liver diseases was <1.5 years in 5 patients. MN was associated with a broad spectrum of liver diseases including primary biliary cirrhosis (PBC), autoimmune hepatitis (AIH), and primary sclerosing cholangitis (PSC). AIH whether isolated (n = 3) or associated with PBC (n = 2) or PSC (n = 2) was the most frequent autoimmune liver disease. Circulating PLA2R antibodies were detected in 4 out of 9 patients but the test was performed under specific immunosuppressive treatment in 3 out of 9 patients. Seven of the 9 patients with available renal tissue specimens displayed enhanced expression of PLA2R in glomeruli whereas PLA2R was not expressed in liver parenchyma from these patients or in normal liver tissue. The study of immunoglobulin (Ig) subclasses of deposits in glomeruli revealed that the most frequent pattern was the coexistence of IgG1 and IgG4 immune deposits with IgG4 predominating.Detection of PLA2R antibodies in glomeruli but not in liver parenchyma is a common finding in patients with MN associated with autoimmune liver disease, suggesting that these autoantibodies are not exclusively detected in idiopathic MN.

  12. Importance of public relations in recycling strategies: principles and case studies.

    Science.gov (United States)

    Salhofer, Stefan; Isaac, Nicole A

    2002-07-01

    The separate collection of waste, and especially of recyclables with specific collection systems, would not be possible without the involvement of the users. Apart from the physical installations such as collection containers, collection points, etc., the motivation of the users is an essential component. Motivation can be reinforced through public relations work. In addition to the underlying technical considerations, this paper describes the difference between communication in general and public relations and specifically examines public involvement in recycling. Through the use of examples, we look at the targeted users and typical media employed. Furthermore, we analyzes the development of public involvement. The examples show that public relations for recycling strategies relies to a great extent on attitudes, habits, and access to the target group. Thus, standardized procedures cannot be developed. For these reasons, public relation activities must be planned carefully and professionally and include an analysis of the target group, choice of media, and verification of success.

  13. The General Stanley McChrystal Affair: A Case Study in Civil-Military Relations

    Science.gov (United States)

    2011-01-01

    OPMEP did not specifically direct its instruction. Indeed, the OPMEP directs only one PME institution to specifi- cally teach civil-military...relations, the National War College.63 The OPMEP guidance for the other war colleges does not preclude the teaching of civil-military relations, but it does...Administration,” CBSnews.com: Washington Unplugged , 23 Jun 10; http://www.cbsnews.com/video/watch/?id=6610855n&tag=cont entMain;contentBody (accessed June 13

  14. Case study

    DEFF Research Database (Denmark)

    Milana, Marcella; Bernt Sørensen, Tore

    of several DHSs. Furthermore ?Udspil? was chosen for being a non-formal learning activity based on individual participation, even though linked to institutionalized learning practices, which were carried out in cooperation between several local institutions.Last but not least, the project represents...... that time Roskilde University Centre and Learning Lab Denmark, DK)3. The case here presented is based on results from research activity carried out over a 1 year period (spring 2006 - spring 2007). Detailed information concerning participation in the project was collected in two DHSs only: the Sports Day......Learning for democratic citizenship is embedded in the general popular education ideal(folkeoplysning), which is the primary source of inspiration for the Day High Schools (DHSs). DHSs are private institutions supported by local authorities, that host primarily low educated and unemployed young...

  15. Rehabilitating mangrove ecosystem services: A case study on the relative benefits of abandoned pond reversion from Panay Island, Philippines.

    Science.gov (United States)

    Duncan, Clare; Primavera, Jurgenne H; Pettorelli, Nathalie; Thompson, Julian R; Loma, Rona Joy A; Koldewey, Heather J

    2016-08-30

    Mangroves provide vital climate change mitigation and adaptation (CCMA) ecosystem services (ES), yet have suffered extensive tropics-wide declines. To mitigate losses, rehabilitation is high on the conservation agenda. However, the relative functionality and ES delivery of rehabilitated mangroves in different intertidal locations is rarely assessed. In a case study from Panay Island, Philippines, using field- and satellite-derived methods, we assess carbon stocks and coastal protection potential of rehabilitated low-intertidal seafront and mid- to upper-intertidal abandoned (leased) fishpond areas, against reference natural mangroves. Due to large sizes and appropriate site conditions, targeted abandoned fishpond reversion to former mangrove was found to be favourable for enhancing CCMA in the coastal zone. In a municipality-specific case study, 96.7% of abandoned fishponds with high potential for effective greenbelt rehabilitation had favourable tenure status for reversion. These findings have implications for coastal zone management in Asia in the face of climate change.

  16. The KULTURisk Regional Risk Assessment methodology for water-related natural hazards - Part 2: Application to the Zurich case study

    Science.gov (United States)

    Ronco, P.; Bullo, M.; Torresan, S.; Critto, A.; Olschewski, R.; Zappa, M.; Marcomini, A.

    2014-07-01

    The main objective of the paper is the application of the KULTURisk Regional Risk Assessment (KR-RRA) methodology, presented in the companion paper (Part 1, Ronco et al., 2014), to the Sihl River valley, in Switzerland. Through a tuning process of the methodology to the site-specific context and features, flood related risks have been assessed for different receptors lying on the Sihl River valley including the city of Zurich, which represents a typical case of river flooding in urban area. After characterizing the peculiarities of the specific case study, risk maps have been developed under a 300 years return period scenario (selected as baseline) for six identified relevant targets, exposed to flood risk in the Sihl valley, namely: people, economic activities (including buildings, infrastructures and agriculture), natural and semi-natural systems and cultural heritage. Finally, the total risk index map, which allows to identify and rank areas and hotspots at risk by means of Multi Criteria Decision Analysis tools, has been produced to visualize the spatial pattern of flood risk within the area of study. By means of a tailored participative approach, the total risk maps supplement the consideration of technical experts with the (essential) point of view of the relevant stakeholders for the appraisal of the specific scores and weights related to the receptor-relative risks. The total risk maps obtained for the Sihl River case study are associated with the lower classes of risk. In general, higher relative risks are concentrated in the deeply urbanized area within and around the Zurich city centre and areas that rely just behind to the Sihl River course. Here, forecasted injuries and potential fatalities are mainly due to high population density and high presence of old (vulnerable) people; inundated buildings are mainly classified as continuous and discontinuous urban fabric; flooded roads, pathways and railways, the majority of them referring to the Zurich main

  17. Crime in relation to urban design. Case study: The Greater Cairo Region

    Directory of Open Access Journals (Sweden)

    Heba Adel

    2016-09-01

    Full Text Available Crime is a part of any social system and known to human communities since its origins. It differs from community to another, even within one community it doesn’t occur equally in all places and nor by the same way. It is also concentrated in some places more than others, sometimes increases, sometimes decreases, etc. Previous researches have proved that crime rate has significant correlation with different social factors: education levels, poverty rates and lack of social organization, while others have drawn the attention to its relation with the built environment. They proposed that crime occurs in places where both opportunities and criminals are available. The role of this paper is to identify urban circumstances related to crime occurrence within the Greater Cairo Region, and to propose different ways to reduce these crimes. Consecutively, agglomeration’s main districts were scrutinized according to social analysis, street-network pattern and land-use.

  18. Credit-Related Practices of Islamic Banks in Comparison with Theory: Case Study of Turkey

    Directory of Open Access Journals (Sweden)

    Z. Hafsa ORHAN ASTRÖM

    2016-11-01

    Full Text Available Abstract The aim of this paper is to analyse credit-related practices of Islamic banks in Turkey in comparison with theory. Here, ‘credit-related practices’ are, first, the bank balance sheet item called ‘loans’ in general, and second, loans in terms of their types. By ‘theory’ we mean Islamic economics. In attaining the aim of this paper, we use comparative methodology depending on quantitative and qualitative research. In this context, we utilize quantitative methods like collecting calculating and representing -through figures and charts- relevant data, and qualitative methods such as searching through, selecting, summarizing and evaluating relevant literature and documents like agreements and reports concerning the subject. Some of the outstanding results of this paper are as follows; loans are the dominant use of funds for Turkish Islamic banks with changing ratios between 60-75% for the period of December 2005-June 2015 and the main method used for loans is murabahah with 99.7% as of June 2015. Secondly, 91% of household loans are in the form of consumer credits as of June 2015, among which house loans are sweepingly dominant. Credits by individual credit cards have been on the increase until the second half of 2013. Keywords: Islamic banking, credit-related practices, theory, Turkey.

  19. Evaluation of economic loss from energy-related environmental pollution: a case study of Beijing

    Science.gov (United States)

    Chen, Chen; Su, Meirong; Liu, Gengyuan; Yang, Zhifeng

    2013-09-01

    With the growth of energy consumption, energy-related environmental pollution has become increasingly serious, which in turn causes enormous economic loss because of public health damage, corrosion of materials, crop yield reduction, and other factors. Evaluating economic loss caused by energy-related environmental pollution can contribute to decision making in energy management. A framework for evaluating economic loss from environmental pollution produced during energy production, transportation, and consumption is proposed in this paper. Regarding SO2, PM10, and solid waste as the main pollutants, economic losses from health damage, materials corrosion, crop yield reduction, and solid waste pollution are estimated based on multiple concentration-response relationships and dose-response functions. The proposed framework and evaluation methods are applied to Beijing, China. It is evident that total economic loss attributable to energy-related environmental pollution fluctuated during 2000-2011 but had a general growth trend, with the highest value reaching 2.3 × 108 CNY (China Yuan) in 2006. Economic loss caused by health damage contributes most to the total loss among the four measured damage types. The total economic loss strongly correlates with the amount of energy consumption, especially for oil and electricity. Our evaluation framework and methods can be used widely to measure the potential impact of environmental pollution in the energy lifecycle.

  20. Examining participation in relation to students’ development of health- related action competence in a whole school food setting: Insights from the ‘LOMA’ case study

    DEFF Research Database (Denmark)

    Ruge, Dorte; Nielsen, Morten Kromann; Mikkelsen, Bent Egberg

    2015-01-01

    Purpose: The aim of this paper is to examine, how students’ participation in an integrated school food program was related to the development of components of food and health-related action competence (F&HRAC). These components were understood as knowledge, insight, motivation, ownership and social...... skills that made students able to take action regarding food and health in everyday life. Methods: Research was undertaken as a single case study of the development of an integrated education and health program called LOMA-Local Food (LOMA) in a secondary school in Denmark. Qualitative methods were...... their own school food as integrated in curriculum. Research applied the Health Promoting Schools’ (HPS) conceptual framework and the IVACE approach. Findings: Findings suggest, that students who participated in LOMA educational activities became motivated for developing a food and health-related action...

  1. Can we reconcile individualisation with relational ‘personhood: a case study from the Early Neolithic

    Directory of Open Access Journals (Sweden)

    Chapman John

    2011-12-01

    Full Text Available In this article, we seek to discuss the tension between relational personhood, characterised by ‘dividuals’, and the individualisation of persons whose driving force was the creation of new embodied skills learnt to perform the wide range of new tasks which defined the farming way of life. This is, in effect, an exploration of the consequences of a vivid new world itself created by the interactions of a wider variety of individuals with different skills than had ever been seen before, including those required for domesticating animals, potting, building rectangular houses, growing cereals and pulses and polishing stone tools and ornaments.

  2. The variability of processes involved in transgene dispersal - case studies from Brassica and related genera

    DEFF Research Database (Denmark)

    Bagger Jørgensen, Rikke; Hauser, Thure Pavlo; D'Hertefeldt, T.

    2009-01-01

    Background, aim, and scope We strive to predict consequences of genetically modified plants (GMPs) being cultivated openly in the environment, as human and animal health, biodiversity, agricultural practise and farmers’ economy could be affected. Therefore, it is unfortunate that the risk...... is a valuable tool in identifying key factors in the gene-flow process for which more knowledge is needed, and identifying parameters and processes which are relatively insensitive to change and therefore require less attention in future collections of data. But the interdependence between models...

  3. Sclerosis in bisphosphonate-related osteonecrosis of the jaws and its correlation with the clinical stages: study of 43 cases.

    Science.gov (United States)

    Bagan, J V; Cibrian, R M; Lopez, J; Leopoldo-Rodado, M; Carbonell, E; Bagán, L; Utrilla, J; Scully, C

    2015-03-01

    We analysed the degree of sclerosis in the different stages of bisphosphonate-related osteonecrosis of the jaws (BRONJ) and studied the relation between the grade of sclerosis, the clinical symptoms, and the depth of lucency. We compared 43 patients with mandibular BRONJ with a control group of 40 cases with no bony lesions. The presence of sclerotic bone, cortical irregularities, radiolucency, fragmentation or sequestration, periostitis, and narrowing of the mandibular canal were studied from computed tomographic (CT) scans using the program ImageJ 1.47v (National Institute of Health, Bethesda, USA) to measure the radiolucency, width of the cortices, and degree of sclerosis. Patients with BRONJ had more severe sclerosis than controls (p0.05). We conclude that the degree of sclerosis increases with the clinical stage of BRONJ, and is correlated with the depth of lucency.

  4. The Information-related Time Loss on Construction Sites: A Case Study on Two Sites

    Directory of Open Access Journals (Sweden)

    Sheng Xu

    2014-08-01

    Full Text Available Information management is essential in construction projects. Existing research has identified and discussed problems in communication and information transfer among different stakeholders, such as the loss of information caused by fragmentation and information islands. However, there are few statistics about the direct time waste caused by information loss arising from poor communication and information management. Existing surveys relying on self-reporting questionnaires and interviews often contain various biases. This paper presents a direct observation of two construction sites in China in relation to wasted time and the information flows in these time-wasting events. Analysis of the observation data provides objective and comprehensive statistics on time wasted due to inconsistent information, dislocation and ambiguity. This research also analyses the correlation between participants, information carriers, information loss and the amount of time wasted. Finally, the wasting of time is analysed from the perspective of information flows and problems that cannot be addressed by information technologies are discussed.

  5. Forecasting of Information Security Related Incidents: Amount of Spam Messages as a Case Study

    Science.gov (United States)

    Romanov, Anton; Okamoto, Eiji

    With the increasing demand for services provided by communication networks, quality and reliability of such services as well as confidentiality of data transfer are becoming ones of the highest concerns. At the same time, because of growing hacker's activities, quality of provided content and reliability of its continuous delivery strongly depend on integrity of data transmission and availability of communication infrastructure, thus on information security of a given IT landscape. But, the amount of resources allocated to provide information security (like security staff, technical countermeasures and etc.) must be reasonable from the economic point of view. This fact, in turn, leads to the need to employ a forecasting technique in order to make planning of IT budget and short-term planning of potential bottlenecks. In this paper we present an approach to make such a forecasting for a wide class of information security related incidents (ISRI) — unambiguously detectable ISRI. This approach is based on different auto regression models which are widely used in financial time series analysis but can not be directly applied to ISRI time series due to specifics related to information security. We investigate and address this specifics by proposing rules (special conditions) of collection and storage of ISRI time series, adherence to which improves forecasting in this subject field. We present an application of our approach to one type of unambiguously detectable ISRI — amount of spam messages which, if not mitigated properly, could create additional load on communication infrastructure and consume significant amounts of network capacity. Finally we evaluate our approach by simulation and actual measurement.

  6. Family lifestyle factors related to children s congenital heart defects in China:a case-control study

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Objective To explore the multiple risk factors for family lifestyle of children with congenital heart defects(CHDs)in Shaanxi Province,China.Methods A 1∶1 case-control study was carried out to investigate 60 pairs of children and their parents.The univariate and multivariable logistic regression models were used to analyze the influence of risk factors related to parents' lifestyle on CHDs.Results Several possible risk factors were found for CHDs,including fever(OR=4.465,P=0.017),pesticides contact(OR=2.234...

  7. Measuring the relative performance in mining industry: A case study of cooperative Seif mining company

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Lotfi

    2013-09-01

    Full Text Available In this paper, we present an empirical study to measure the performance of a salt refinery named Seif cooperative mining. The study uses Political–Economical-Social– Technological Analysis (PEST technique to evaluate opportunities and threats associated with external as well as internal factors influencing the firm. The study designs a questionnaire in Liket scale and asks decision maker to evaluate internal/external threats. In terms of external factors, there are four opportunities and ten threats associated with External factor evaluation (EFE factors. In terms of opportunities, existing potential for export has received the highest priority followed by easy access to national transportation and government support. On the threats part, firm’s dependency on importing necessary parts, global price reduction and mineral reserve termination in near future are the most important issues. In addition, in terms of internal factors, on the opportunity part, access to necessary utilities is considered as the most important factor followed by availability of high level lab equipment and sufficient assets and equities. On the threats, depreciation is considered as the most important issue followed by lack of optimum utilization of equipment and lack of enterprise resource planning. In addition, the study uses balanced score card (BSC technique to look at the performance of the firm in terms of learning and growth, internal process, customer and financials. The study determines the present and ideal status of the firm.

  8. Argumentation as/in/for Dialogical Relation: A Case Study from Elementary School Science

    Science.gov (United States)

    Kim, Mijung; Roth, Wolff-Michael

    2014-01-01

    Argumentation as a form of introducing children to science has received increasing attention over the past decade. Argumentation tends to be studied and theorized through the lens of individual speakers, who contribute to a conversation by means of opposing statements. M.M. Bakhtin and L.S. Vygotsky independently proposed a very different approach…

  9. Relation between blood vitamin B12 levels with premature ejaculation: case-control study.

    Science.gov (United States)

    Kadihasanoglu, M; Kilciler, M; Kilciler, G; Yucetas, U; Erkan, E; Karabay, E; Toktas, M G; Kendirci, M

    2016-09-29

    The aim of this study was to investigate whether vitamin B12 levels are associated with premature ejaculation (PE). A total of 109 subjects (56 PE and 53 controls) were included in this study. PE was defined as self-reported intravaginal ejaculatory latency time (IELT) based on the Diagnostic and Statistical Manual of Mental Disorders IV criteria and those who had had an IELT of premature ejaculation diagnostic tool (PEDT), International Index of Erectile Function (IIEF) and Beck Depression Inventory (BDI). The vitamin 12 levels were measured in all subjects. The mean age between the PE and controls was comparable (p = .084). Mean IIEF and BDI scores between the two groups did not statistically differ. The mean IELT values in the PE group were significantly lower than in the control group (p < .0001). PE patients reported significantly lower vitamin B12 levels compared with the controls (213.14 vs. 265.89 ng ml(-1) ; p < .001). The ROC analysis showed a significant correlation between the diagnosis of PE and lower vitamin B12 levels. This study has demonstrated that lower vitamin B12 levels are associated with the presence of PE. This work also shows a strong correlation between vitamin B12 levels and the PEDT scores as well as the IELT values.

  10. Leisure time activities related to carcinogen exposure and lung cancer risk in never smokers. A case-control study

    Energy Technology Data Exchange (ETDEWEB)

    Ruano-Ravina, Alberto, E-mail: alberto.ruano@usc.es [Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela (Spain); CIBER de Epidemiología y Salud Pública CIBERESP, Barcelona (Spain); García-Lavandeira, José Antonio [Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela (Spain); Department of Preventive Medicine, A Coruña University Hospital Complex, Coruña (Spain); Torres-Durán, María [Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela (Spain); Service of Neumology, University Hospital Complex of Vigo, Vigo (Spain); Prini-Guadalupe, Luciana [Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela (Spain); Parente-Lamelas, Isaura [Service of Neumology, Ourense Hospital Complex, Ourense (Spain); Leiro-Fernández, Virginia [Service of Neumology, University Hospital Complex of Vigo, Vigo (Spain); Montero-Martínez, Carmen [Service of Neumology, University Hospital Complex of A Coruña, Coruña (Spain); González-Barcala, Francisco Javier; Golpe-Gómez, Antonio [Service of Neumology, Santiago de Compostela University Clinic Hospital, Santiago de Compostela (Spain); Martínez, Cristina [National Institute of Silicosis, University Hospital of Asturias, Oviedo, Asturias (Spain); Castro-Añón, Olalla [Service of Neumology, Hospital Lucus Augusti, Lugo (Spain); Mejuto-Martí, María José [Service of Neumology, Hospital Arquitecto Marcide, Ferrol (Spain); and others

    2014-07-15

    We aim to assess the relationship between leisure time activities related to exposure to carcinogenic substances and lung cancer risk in a hospital-based case-control study performed in never smokers. We included never smoking cases with anatomopathologically confirmed lung cancer and never smoking controls undergoing trivial surgery, at 8 Spanish hospitals. The study was conducted between January 2011 and June 2013. Participants were older than 30 and had no previous neoplasms. All were personally interviewed focusing on lifestyle, environmental tobacco smoke exposure, occupational history and leisure time activities (including duration of such activities). Results were analyzed through logistic regression and adjusted also by residential radon and education level. We included 513 never smokers, 191 cases and 322 controls. The OR for those performing the studied leisure time activities was 1.43 (95%CI 0.78–2.61). When we restricted the analysis to those performing do-it-yourself activities for more than 10 years the OR was 2.21 (95%CI 0.93–5.27). Environmental tobacco smoke exposure did not modify this association. The effect for the different lung cancer histological types was very close to significance for adenocarcinoma but only when these activities were performed for more than 10 years. We encourage health professionals to recommend protective measures for those individuals while performing these hobbies to reduce the risk of lung cancer. - Highlights: • Some leisure time activities are associated with the exposure to carcinogenic substances. • These activities are model-making, painting (artistic or not), furniture refinishing or wood working. • Few studies have assessed lung cancer risk due to these hobbies and none in never-smokers. • Leisure activities related to exposure to carcinogenic substances present higher lung cancer risk. • The risk is higher when these activities are performed for more than 10 years.

  11. Reactive arthritis in relation to internal derangements of the temporomandibular joint: a case control study.

    Science.gov (United States)

    Lund, Bodil; Holmlund, Anders; Wretlind, Bengt; Jalal, Shah; Rosén, Annika

    2015-09-01

    The aim of this study was to find out if reactive arthritis was involved in the aetiology of chronic closed lock of the temporomandibular joint (TMJ) by looking for bacterial antigens in the synovial membrane of the TMJ, and by studying the antibody serology and carriage of human leucocyte antigen (HLA) B27 in patients with chronic closed lock. Patients with reciprocal clicking and healthy subjects acted as controls. We studied a total of 43 consecutive patients, 15 with chronic closed lock, 13 with reciprocal clicking, and 15 healthy controls with no internal derangements of the TMJ. Venous blood samples were collected from all subjects for measurement of concentrations of HLA tissue antigen and serology against Chlamydia trachomatis, Yersinia enterocolitica, Salmonella spp., Campylobacter jejuni, and Mycoplasma pneumoniae. Samples of synovial tissue from patients with closed lock and reciprocal clicking were obtained during discectomy and divided into two pieces, the first of which was tested by strand displacement amplification for the presence of C trachomatis, and the second of which was analysed for the presence of species-specific bacterial DNA using 16s rRNA pan-polymerase chain reaction (PCR). There were no significant differences between the groups in the incidence of antibodies against M pneumoniae, Salmonella spp. or Y enterocolitica. No patient had antibodies towards C trachomatis or C jejuni. We found no bacterial DNA in the synovial fluid from any patient. The HLA B27 antigen was present in 2/15 subjects in both the closed lock and control groups, and none in the reciprocal clicking group. In conclusion, reactive arthritis does not seem to be the mechanism of internal derangement of the TMJ.

  12. Cardiovascular System Changes and Related Risk Factors in Acromegaly Patients: A Case-Control Study

    Directory of Open Access Journals (Sweden)

    Xiaopeng Guo

    2015-01-01

    Full Text Available Background. Cardiovascular complications are known to be the main determinants of reduced life expectancy and decreased quality of life in acromegaly patients. Our study aimed to provide insight into the cardiovascular changes that occur in acromegaly patients and to investigate the correlative risk factors. Methods. A total of 108 patients definitively diagnosed with acromegaly and 108 controls matched for age and gender were recruited into study and control groups, respectively. Standard echocardiography was performed on all of the participants, and data were collected and analyzed. Results. All acromegaly patients presented with structural cardiac changes, including a larger heart cavity, thicker myocardial walls, and increased great vessel diameters compared with the control group. Additionally, the acromegaly patients presented with reduced diastolic function. Aging and increased body mass index (BMI were correlated with myocardial hypertrophy and diastolic dysfunction; a longer disease duration was correlated with larger great vessel diameters. Conclusions. Ageing and increased BMI are independent risk factors for acromegalic cardiomyopathy, and a long disease duration results in the expansion of great vessels. Increased efforts should be made to diagnose acromegaly at an early stage and to advise acromegaly patients to maintain a healthy weight.

  13. Cardiovascular System Changes and Related Risk Factors in Acromegaly Patients: A Case-Control Study.

    Science.gov (United States)

    Guo, Xiaopeng; Gao, Lu; Zhang, Shuo; Li, Yilin; Wu, Yue; Fang, Ligang; Deng, Kan; Yao, Yong; Lian, Wei; Wang, Renzhi; Xing, Bing

    2015-01-01

    Background. Cardiovascular complications are known to be the main determinants of reduced life expectancy and decreased quality of life in acromegaly patients. Our study aimed to provide insight into the cardiovascular changes that occur in acromegaly patients and to investigate the correlative risk factors. Methods. A total of 108 patients definitively diagnosed with acromegaly and 108 controls matched for age and gender were recruited into study and control groups, respectively. Standard echocardiography was performed on all of the participants, and data were collected and analyzed. Results. All acromegaly patients presented with structural cardiac changes, including a larger heart cavity, thicker myocardial walls, and increased great vessel diameters compared with the control group. Additionally, the acromegaly patients presented with reduced diastolic function. Aging and increased body mass index (BMI) were correlated with myocardial hypertrophy and diastolic dysfunction; a longer disease duration was correlated with larger great vessel diameters. Conclusions. Ageing and increased BMI are independent risk factors for acromegalic cardiomyopathy, and a long disease duration results in the expansion of great vessels. Increased efforts should be made to diagnose acromegaly at an early stage and to advise acromegaly patients to maintain a healthy weight.

  14. Impact of relative humidity on visibility degradation during a haze event: A case study.

    Science.gov (United States)

    Deng, Hua; Tan, Haobo; Li, Fei; Cai, Mingfu; Chan, P W; Xu, Hanbing; Huang, Xiaoying; Wu, Dui

    2016-11-01

    Light scattering of aerosols depends on ambient relative humidity (RH) since hygroscopic particles absorb significant water at high RH, and this results in low visibility. This paper used custom-made parallel nephelometers (PNEPs) to measure aerosol light scattering enhancement factor ƒ(RH), and utilized data including visibility, PM2.5, black carbon, water-soluble ions mass concentrations and surface meteorological parameters, in conjunction with background weather conditions, to analyze a haze event in Guangzhou during 8th-15th Dec. 2013. Unfavorable weather conditions, such as high RH and low wind speed, were observed during the haze event. The hourly average mass concentration of PM2.5 was 127μg/m(3), with concentration of 192.4μg/m(3) on 9th and 196μg/m(3) on 13th. The ƒ(RH) did not exhibit significant changes during this haze process, with value of ƒ(80%)=1.58±0.07. Although the mass fraction of water-soluble ions to PM2.5 decreased after 12th Dec., the aerosol hygroscopicity might not have changed significantly since the mass fraction of nitrate became more dominant, which has stronger ability to take up water. The best-fitted parameterized function for ƒ(RH) is ƒ(RH)=0.731+0.1375∗(1-RH/100)(-1)+0.00719∗(1-RH/100)(-2). Combining the fixed parameterization of ƒ(RH) above, the visibility was calculated with the measured light scattering and absorption coefficient of particles and gas under dry condition, as well as ambient RH. The predicted visibility range agrees well with the measurements without precipitation. Using ISORROPIA II model, the calculated aerosol liquid water content (ALWC) at ambient RH varied consistently with the PM2.5 under lower RH, while it was more influenced by high RH. This work also show that high RH accompanied with precipitation will enhance aerosol hygroscopic growth effect, leading to further visibility degradation, even if PM2.5 mass decreased due to precipitation.

  15. Identification of the Risk Related to a Process on Hospital Emergency Service: a Case Study

    CERN Document Server

    Santos, Carlos; Ferreira, Carla; Tribolet, José

    2011-01-01

    This paper, framed in a vast investigation, describes the application of techniques and methodologies in Organizational Engineering connected to the associated risk to the processes developed in an Emergency Service of an important Portuguese Hospital. The transactions performed in an emergency service and the consequent risk identification (negative behaviour associated to those transactions) is done based on static and dynamic models, developed during the business modelling. Any non-trivial system is better portrayed trough a small number of reasonably independent models. From this point of view it is important to look at the systems from a "micro" perspective, which allows us to analyse the system at the transaction level. All processes have some associated risk (inherent risk). Its identification will be decisive for future analysis and for the consequent decision over the need, or not, to study internal control mechanisms. This decision will depend on the risk level that the organization considers accept...

  16. Aldehydes in relation to air pollution sources: A case study around the Beijing Olympics

    Science.gov (United States)

    Altemose, Brent; Gong, Jicheng; Zhu, Tong; Hu, Min; Zhang, Liwen; Cheng, Hong; Zhang, Lin; Tong, Jian; Kipen, Howard M.; Ohman-Strickland, Pamela; Meng, Qingyu; Robson, Mark G.; Zhang, Junfeng

    2015-05-01

    This study was carried out to characterize three aldehydes of health concern (formaldehyde, acetaldehyde, and acrolein) at a central Beijing site in the summer and early fall of 2008 (from June to October). Aldehydes in polluted atmospheres come from both primary and secondary sources, which limits the control strategies for these reactive compounds. Measurements were made before, during, and after the Beijing Olympics to examine whether the dramatic air pollution control measures implemented during the Olympics had an impact on concentrations of the three aldehydes and their underlying primary and secondary sources. Average concentrations of formaldehyde, acetaldehyde and acrolein were 29.3 ± 15.1 μg/m3, 27.1 ± 15.7 μg/m3 and 2.3 ± 1.0 μg/m3, respectively, for the entire period of measurements, all being at the high end of concentration ranges measured in cities around the world in photochemical smog seasons. Formaldehyde and acrolein increased during the pollution control period compared to the pre-Olympic Games, followed the changing pattern of temperature, and were significantly correlated with ozone and with a secondary formation factor identified by principal component analysis (PCA). In contrast, acetaldehyde had a reduction in mean concentration during the Olympic air pollution control period compared to the pre-Olympic period and was significantly correlated with several pollutants emitted from local emission sources (e.g., NO2, CO, and PM2.5). Acetaldehyde was also more strongly associated with primary emission sources including vegetative burning and oil combustion factors identified through the PCA. All three aldehydes were lower during the post-Olympic sampling period compared to the before and during Olympic periods, likely due to seasonal and regional effects. Our findings point to the complexity of source control strategies for secondary pollutants.

  17. Case-control study of disturbed eating behaviors and related psychographic characteristics in young adults with and without diet-related chronic health conditions.

    Science.gov (United States)

    Quick, Virginia M; McWilliams, Rita; Byrd-Bredbenner, Carol

    2012-08-01

    Young adults with diet-related chronic health conditions (DRCHCs; i.e., type 1 diabetes, celiac disease, cystic fibrosis, inflammatory bowel diseases, irritable bowel syndrome) face challenges complying with dietary restrictions required to effectively manage their health condition. These restrictions could put them at risk for disturbed eating. The purpose of this study was to determine if young adults with and without DRCHCs differed with regard to disturbed eating behaviors and related psychographics characteristics (i.e., body image attributes, mental disorders, intrapersonal characteristics and sociocultural environment [i.e., media and family]). Each DRCHC participant (cases=166) was matched to 4 healthy participants (controls=664) based on gender and BMI (±0.50 BMI units). Conditional logistic regression analyses indicate cases were twice as likely to have been diagnosed by a healthcare provider with an eating disorder (p=0.08, OR=1.99, CI(90) [1.03-3.83]). Cases were significantly more likely to use Inappropriate Compensatory Behaviors to manage their weight, i.e., excessive exercise (p=0.04, OR=1.41, CI(95) [1.02-1.94]) and misuse medication (p=0.04, OR=1.14, CI(95) [1.00-1.29]) than controls. Depression and anxiety were significantly higher, and health status was significantly poorer in cases compared with controls. DRCHC participants were less likely to report feeling body image pressures from the media, placed a greater value on their health, used social diversion, and recalled a greater emphasis being placed on their mothers' weights and mealtimes being less structured than control participants. Findings indicate that nutrition and other healthcare professionals should incorporate screening DRCHC patients for disturbed eating behaviors and eating disorders in their standards of care.

  18. The Impact of the Prior Density on a Minimum Relative Entropy Density: A Case Study with SPX Option Data

    Directory of Open Access Journals (Sweden)

    Cassio Neri

    2014-05-01

    Full Text Available We study the problem of finding probability densities that match given European call option prices. To allow prior information about such a density to be taken into account, we generalise the algorithm presented in Neri and Schneider (Appl. Math. Finance 2013 to find the maximum entropy density of an asset price to the relative entropy case. This is applied to study the impact of the choice of prior density in two market scenarios. In the first scenario, call option prices are prescribed at only a small number of strikes, and we see that the choice of prior, or indeed its omission, yields notably different densities. The second scenario is given by CBOE option price data for S&P500 index options at a large number of strikes. Prior information is now considered to be given by calibrated Heston, Schöbel–Zhu or Variance Gamma models. We find that the resulting digital option prices are essentially the same as those given by the (non-relative Buchen–Kelly density itself. In other words, in a sufficiently liquid market, the influence of the prior density seems to vanish almost completely. Finally, we study variance swaps and derive a simple formula relating the fair variance swap rate to entropy. Then we show, again, that the prior loses its influence on the fair variance swap rate as the number of strikes increases.

  19. KULTURisk regional risk assessment methodology for water-related natural hazards - Part 2: Application to the Zurich case study

    Science.gov (United States)

    Ronco, P.; Bullo, M.; Torresan, S.; Critto, A.; Olschewski, R.; Zappa, M.; Marcomini, A.

    2015-03-01

    The aim of this paper is the application of the KULTURisk regional risk assessment (KR-RRA) methodology, presented in the companion paper (Part 1, Ronco et al., 2014), to the Sihl River basin, in northern Switzerland. Flood-related risks have been assessed for different receptors lying on the Sihl River valley including Zurich, which represents a typical case of river flooding in an urban area, by calibrating the methodology to the site-specific context and features. Risk maps and statistics have been developed using a 300-year return period scenario for six relevant targets exposed to flood risk: people; economic activities: buildings, infrastructure and agriculture; natural and semi-natural systems; and cultural heritage. Finally, the total risk index map has been produced to visualize the spatial pattern of flood risk within the target area and, therefore, to identify and rank areas and hotspots at risk by means of multi-criteria decision analysis (MCDA) tools. Through a tailored participatory approach, risk maps supplement the consideration of technical experts with the (essential) point of view of relevant stakeholders for the appraisal of the specific scores weighting for the different receptor-relative risks. The total risk maps obtained for the Sihl River case study are associated with the lower classes of risk. In general, higher (relative) risk scores are spatially concentrated in the deeply urbanized city centre and areas that lie just above to river course. Here, predicted injuries and potential fatalities are mainly due to high population density and to the presence of vulnerable people; flooded buildings are mainly classified as continuous and discontinuous urban fabric; flooded roads, pathways and railways, most of them in regards to the Zurich central station (Hauptbahnhof) are at high risk of inundation, causing severe indirect damage. Moreover, the risk pattern for agriculture, natural and semi-natural systems and cultural heritage is relatively

  20. Risk factors associated with sick leave due to work-related injuries in Dutch farmers: an exploratory case-control study

    NARCIS (Netherlands)

    Hartman, E.; Frankena, K.; Oude Vrielink, H.H.E.; Nielen, M.; Metz, J.H.M.; Huirne, R.B.M.

    2004-01-01

    Using data from an insurance company, the occurrence of sick leave among Dutch farmers due to work-related injuries, and the epidemiological risk factors were investigated. In this case-control study the cases had filed a sick leave claim for work-related injury from 19982001 and the controls had no

  1. Case Study: Writing a Journal Case Study

    Science.gov (United States)

    Prud'homme-Genereux, Annie

    2016-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue describes incorporating a journal article into the classroom by first converting it into a case study.

  2. Haplotypes in IL-8 Gene Are Associated to Age-Related Macular Degeneration: A Case-Control Study.

    Directory of Open Access Journals (Sweden)

    Federico Ricci

    Full Text Available Age-related macular degeneration (AMD is the main cause of blindness in the developed world. The etiology of AMD is multifactorial due to the interaction between genetic and environmental factors. IL-8 has a role in inflammation and angiogenesis; we report the genetic characterization of IL-8 allele architecture and evaluate the role of SNPs or haplotypes in the susceptibility to wet AMD, case-control study.Case-control study including 721 AMD patients and 660 controls becoming from Italian population. Genotyping was carried out by Real Time-PCR. Differences in the frequencies were estimated by the chi-square test. Direct sequencing was carried out by capillary electrophoresis trough ABI3130xl.rs2227306 showed a p-value of 4.15*10(-5 and an Odds Ratio (OR for T allele of 1.39 [1.19-1.62]. After these positive results, we sequenced the entire IL-8 regulatory and coding regions of 60 patients and 30 controls stratified for their genotype at rs2227306. We defined two different haplotypes involving rs4073 (A/T, rs2227306 (C/T, rs2227346 (C/T and rs1126647 (A/T: A-T-T-T (p-value: 2.08*10(-9; OR: 1.68 [1.43-1.97] and T-C-C-A (p-value: 7.07*10(-11; OR: 0.60 [0.51-0.70]. To further investigate a potential functional role of associated haplotypes, we performed an expression study on RNA extracted from whole blood of 75 donors to verify a possible direct correlation between haplotype and gene expression, failing to reveal significant differences.These results suggest a possible secondary role of IL-8 gene in the development of the disease. This paper outlines the importance of association between inflammation and AMD. Moreover IL-8 is a new susceptibility genomic biomarker of AMD.

  3. Understanding and mapping local conflicts related to protected areas in small islands: a case study of the Azores archipelago

    Directory of Open Access Journals (Sweden)

    Chiara Bragagnolo

    2016-05-01

    Full Text Available Establishing Protected Areas (PAs is considered one of the most appropriate ways to conserve nature and cultural landscapes. However, conservation constraints can generate social conflicts, especially at a local level. In small islands (SIs, local conflicts may escalate due to an increase in competition for limited space and resources. Pico island in the Azores Archipelago (Portugal, part of the Outermost European region, was considered a good case to study conservation-development conflicts due to the amount of designated protected land (> 35% of its surface and the approval of a new Azorean PA network in 2007. This paper presents a new approach to understanding and mapping local conflicts within PAs in SIs by integrating qualitative data and spatially explicit information. This research takes stock of the benefits, needs and constraints related to Pico Natural Park as perceived by local stakeholders through face-to-face semi-structured interviews; it subsequently identifies and transposes the conflicts distilled from stakeholder discourse into spatially representative visual maps via GIS. Research outcomes show that PAs are perceived mainly as constraints to local development, showing inconsistency between local expectations and regional conservation policy. This highlights the importance of including public participation processes prior to any implementation of conservation strategies. The proposed method provides a springboard towards effective conflict management for PAs on Pico island, showing a relatively low-cost and straightforward approach to minimising future local conflicts which could be adapted to other similar Outermost European regions and SIs.

  4. Case Study Teaching

    Science.gov (United States)

    Herreid, Clyde Freeman

    2011-01-01

    This chapter describes the history of case study teaching, types of cases, and experimental data supporting their effectiveness. It also describes a model for comparing the efficacy of the various case study methods. (Contains 1 figure.)

  5. Travel-Related Venous Thrombosis: Results from a Large Population-Based Case Control Study (MEGA Study)

    NARCIS (Netherlands)

    Cannegieter, Suzanne C.; Doggen, Carine J.M.; Houwelingen, van Hans C.; Rosendaal, Frits R.

    2006-01-01

    Background Recent studies have indicated an increased risk of venous thrombosis after air travel. Nevertheless, questions on the magnitude of risk, the underlying mechanism, and modifying factors remain unanswered. Methods and Findings We studied the effect of various modes and duration of travel o

  6. The shaping of environmental concern in product chains: analysing Danish case studies on environmental aspects in product chain relations

    DEFF Research Database (Denmark)

    Forman, Marianne; Hansen, Anne Grethe; Jørgensen, Michael Søgaard

    Environmental Protection Agency has supported a number of greening activities in the 1990s. On the background of ten case studies of greening activities within the textile sector, the mechanisms of emergence and stabilisation of environmental concerns and practices are analysed and the interaction between......Companies and governments, particularly in the industrialised countries are increasingly aware of the environmental consequences of production, and ‘greening activities’ have increasingly played a role in company strategy and government policy. This has also been the case in Denmark, and the Danish...... chain, which the case company represents, are identified. Direct customer and regulatory demands, as well as indirect societal and regulatory demands are mapped, and their role for product chain greening analysed. The case studies point to the importance of customer demand, regulation and potentially...

  7. A shared frailty model for case-cohort samples: parent and offspring relations in an adoption study

    DEFF Research Database (Denmark)

    Petersen, Liselotte; Sørensen, Thorkild I A; Andersen, Per Kragh

    2010-01-01

    of their biological and adoptive parents were collected with the purpose of studying the association of survival between the adoptee and his/her biological or adoptive parents. Motivated by this study, we explored how to make inference in a shared frailty model for case-cohort data. Our approach was to use inverse......The Danish adoption register contains data on the 12 301 Danish nonfamilial adoptions during 1924-1947. From that register a case-cohort sample was selected consisting of all case adoptees, that is those adoptees dying before age 70 years, and a random sample of 1683 adoptees. The survival data...... probability weighting to account for the sampling in a conditional, shared frailty Poisson model and to use the robust variance estimator proposed by Moger et al. (Statist. Med. 2008; 27:1062-1074).To explore the performance of the estimation procedure, a simulation study was conducted. We studied situations...

  8. Some folded issues related to over-shielded and unplanned rooms for medical linear accelerators - A case study

    Science.gov (United States)

    Muhammad, Wazir; Ullah, Asad; Hussain, Amjad; Ali, Nawab; Alam, Khan; Khan, Gulzar; Matiullah; Maeng, Seongjin; Lee, Sang Hoon

    2015-08-01

    A medical linear accelerator (LINAC) room must be properly shielded to limit the outside radiation exposure to an acceptable safe level defined by individual state and international regulations. However, along with this prime objective, some additional issues are also important. The current case-study was designed to unfold the issues related to over-shielded and unplanned treatment rooms for LINACs. In this connection, an apparently unplanned and over-shielded treatment room of 610 × 610 cm2 in size was compared with a properly designed treatment room of 762 × 762 cm2 in size ( i.e., by following the procedures and recommendations of the IAEA Safety Reports Series No. 47 and NCRP 151). Evaluation of the unplanned room indicated that it was over-shielded and that its size was not suitable for total body irradiation (TBI), although the license for such a treatment facility had been acquired for the installed machine. An overall 14.96% reduction in the total shielding volume ( i.e., concrete) for an optimally planned room as compared to a non-planned room was estimated. Furthermore, the inner room's dimensions were increased by 25%, in order to accommodate TBI patients. These results show that planning and design of the treatment rooms are imperative to avoid extra financial burden to the hospitals and to provide enough space for easy and safe handling of the patients. A spacious room is ideal for storing treatment accessories and facilitates TBI treatment.

  9. Energy and Water Use Related to the Cultivation of Energy Crops: a Case Study in the Tuscany Region

    Directory of Open Access Journals (Sweden)

    Anna Dalla Marta

    2011-06-01

    Full Text Available The contribution of agrobiomasses, as a source of energy, to the reduction of greenhouse gas emissions was confirmed by several studies. Biomass from agriculture represents one of the larger and more diverse sources to exploit and in particular ethanol and diesel have the potential to be a sustainable replacement for fossil fuels, mainly for transport purposes. However, the cultivation of energy crops dedicated to the production of biofuels presents some potential problems, e.g., competitiveness with food crops, water needs, use of fertilizers, etc., and the economic, energy, and environmental convenience of such activity depends on accurate evaluations about the global efficiency of the production system. In this study, the processes related to the cultivation of energy crops were analyzed from an energy and water cost perspective. The crops studied, maize (Zea mais and sunflower (Helianthus annuus, were identified for their different water requirements and cultivation management, which in turns induces different energy costs. A 50-year climatic series of meteorological data from 19 weather stations scattered in the Tuscany region was used to feed the crop model CropSyst for the simulation of crop production, water requirement, and cultivation techniques. Obtained results were analyzed to define the real costs of energy crop cultivation, depending on energy and water balances. In the energy crop cultivation, the only positive energy balance was obtained with the more efficient system of irrigation whereas all the other cases provided negative balances. Concerning water, the results demonstrated that more than 1.000 liters of water are required for producing 1 liter of bioethanol. As a consequence, the cultivation of energy crops in the reserved areas of the region will almost double the actual water requirement of the agricultural sector in Tuscany.

  10. Feasibibility study - cases

    DEFF Research Database (Denmark)

    Lund, Henrik; Hvelplund, Frede Kloster; Sukkumnoed, Decharut

    2004-01-01

    The chapter presents two case studies to show the tools of feasibiliy studies within the context of technological innovation.......The chapter presents two case studies to show the tools of feasibiliy studies within the context of technological innovation....

  11. Project management case studies

    CERN Document Server

    Kerzner, Harold R

    2013-01-01

    A new edition of the most popular book of project management case studies, expanded to include more than 100 cases plus a ""super case"" on the Iridium Project Case studies are an important part of project management education and training. This Fourth Edition of Harold Kerzner''s Project Management Case Studies features a number of new cases covering value measurement in project management. Also included is the well-received ""super case,"" which covers all aspects of project management and may be used as a capstone for a course. This new edition:Contains 100-plus case studies drawn from re

  12. A social work study on detecting organizational and job related factors creating stress: A case study of hydro power employees

    Directory of Open Access Journals (Sweden)

    Ebrahim Jafari

    2012-08-01

    Full Text Available The study investigates different factors influencing people to have more stress in a hydropower unit located in city of Esfahan, Iran. Since there were only 81 people working for customer service section of this company and the proposed study tries to focus only on this part of the firm we have decided to distribute questionnaires among all of them. The questionnaire consists of two parts, in the first part, we gather all private information such as age, gender, education, job experience, etc. through seven important questions. In the second part of the survey, there are 66 questions, which include all the important factors influencing employees' stress. Cronbach alpha is calculated as 0.946, which is well above the minimum acceptable level. The results of our ANOVA tests shows that among different factors, difficulty of working condition as well as work pressure are two most important factors increasing stress among employees. The other findings indicate that there is not a significant difference on work stress among different groups of employees in terms of their job title, educational level, employment type and gender (P>0.05. The other finding indicates that there is a meaningful difference between different groups of people with various ages, marital status and job experience (P>0.05.

  13. Study of Relation between Knowledge Management Components and Innovation in Organization (Case Study: Agricultural Bank Of Kohgiloyeh And Boyerahmad

    Directory of Open Access Journals (Sweden)

    Ebrahim Moradyian

    2016-03-01

    Full Text Available The national organizations such as the obligation to other organizations with other organizations both within and outside the country compete to stay in business. Hence, they should be able to at least one of them on top of your competitors and have the advantage to convince their clients. Information required by the questionnaire Hemmati KM (2010 Innovation Inventory (Kanter, 1988: Saatchi & Partners quotes: 320, is collected. And provide research and surveys to estimate the validity of the inquiry experts and specialists is used. In this study, Cronbach's alpha was used for reliability alpha for the questionnaire KM 0.797 and 0.802 for organizational innovation as measured by the questionnaire is reliable. Spss software to analyze the data and methods of descriptive statistics (frequency, mean, standard deviation for describing data and inferential statistics (Pearson correlation coefficient was used to test the hypothesis. The research result shows that the relationship between knowledge management component of innovation in organizations. Also at the end of recommending the use of research results are presented.

  14. The Relation Between Sacral Angle and Vertical Angle of Sacral Curvature and Lumbar Disc Degeneration: A Case-Control Study.

    Science.gov (United States)

    Ghasemi, Ahmad; Haddadi, Kaveh; Khoshakhlagh, Mohammad; Ganjeh, Hamid Reza

    2016-02-01

    The purpose of this study is to determine the reliability and validity of a goniometric measurement of the vertical angle of the sacrum and sacral angle (SA), and their relationships to lumbar degeneration.A herniated lumbar disc is one of the most frequent medical issues. Investigators in a number of studies have reported associated risk factors for prevalent disc degeneration. Atypical lumbosacral angles and curvature are thought to contribute to the degradation of the spine by many researchers. This study analyzed 360 patients referred to our clinic from 2013 to 2015 due to low back pain. A cross-sectional case-control study was designed in order to compare the sagittal alignment of the lumbosacral area in 3 groups of patients suffering from LBP. A total 120 patients were in a control group with a normal lumbar magnetic resonance imaging (MRI), 120 patients had lumbar disk herniation (LDH), and 120 patients had spinal stenosis. From the sagittal plan of lumbar MRI, SA and vertical angle of sacral curvature (VASC) were determined and then analyzed.The means of VASC in these groups were: 38.98 (SD: 6.36 ± 0.58), 40.89 (SD: 7.69 ± 0.69), and 40.54 (SD: 7.13 ± 0.92), respectively (P = 0.089). Moreover, studies of SA in 3 groups showed that the means of SA were: 39.30 (SD: 6.69 ± 0.63), 40.52 (SD: 7.47 ± 0.65), and 35.63 (SD: 6.07 ± 0.79), respectively. Relation between SA and spinal stenosis was just statistically significant (P ≤ 0.05).One significant limitation of our study is the lack of standing MRI for increased accuracy of measurement. However, we were reluctant to give patients needless exposure to radiation from conventional X-ray, and instead used MRI scans. We did not find any significant correlation between the VASC and LDH in lumbar MRI. Also, SA is not an independent risk factor for LDH in men and women. We suggested that there are several biomechanical factors involved in LDH.

  15. Middle school children's game playing preferences: Case studies of children's experiences playing and critiquing science-related educational games

    Science.gov (United States)

    Joseph, Dolly Rebecca Doran

    The playing of computer games is one of the most popular non-school activities of children, particularly boys, and is often the entry point to greater facility with and use of other computer applications. Children are learning skills as they play, but what they learn often does not generalize beyond application to that and other similar games. Nevertheless, games have the potential to develop in students the knowledge and skills described by national and state educational standards. This study focuses upon middle-school aged children, and how they react to and respond to computer games designed for entertainment and educational purposes, within the context of science learning. Through qualitative, case study methodology, the game play, evaluation, and modification experiences of four diverse middle-school-aged students in summer camps are analyzed. The inquiry focused on determining the attributes of computer games that appeal to middle school students, the aspects of science that appeal to middle school children, and ultimately, how science games might be designed to appeal to middle school children. Qualitative data analysis led to the development of a method for describing players' activity modes during game play, rather than the conventional methods that describe game characteristics. These activity modes are used to describe the game design preferences of the participants. Recommendations are also made in the areas of functional, aesthetic, and character design and for the design of educational games. Middle school students may find the topical areas of forensics, medicine, and the environment to be of most interest; designing games in and across these topic areas has the potential for encouraging voluntary science-related play. Finally, when including children in game evaluation and game design activities, results suggest the value of providing multiple types of activities in order to encourage the full participation of all children.

  16. School-Based Peer-Related Social Competence Interventions for Children with Autism Spectrum Disorder: A Meta-Analysis and Descriptive Review of Single Case Research Design Studies

    Science.gov (United States)

    Whalon, Kelly J.; Conroy, Maureen A.; Martinez, Jose R.; Werch, Brittany L.

    2015-01-01

    The purpose of this review was to critically examine and summarize the impact of school-based interventions designed to facilitate the peer-related social competence of children with autism spectrum disorder (ASD). Reviewed studies employed a single-case experimental design, targeted peer-related social competence, included children 3-12 years old…

  17. The incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of cardiac surgery patients: a prospective nested case-control study.

    NARCIS (Netherlands)

    Vlaar, A.P.J.; Hofstra, J.J.; Determann, R.M.; Veelo, D.P.; Paulus, F.; Kulik, W.; Korevaar, J.; Mol, B.A. de; Koopman, M.M.W.; Porcelijn, L.; Binnekade, J.M.; Vroom, M.B.; Schultz, M.J.; Juffermans, N.P.

    2011-01-01

    Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related morbidity and mortality. Both antibodies and bioactive lipids that have accumulated during storage of blood have been implicated in TRALI pathogenesis. In a single-center, nested, case-control study, patients w

  18. Redefining University Roles in Regional Economies: A Case Study of University-Industry Relations and Academic Organization in Nanotechnology

    Science.gov (United States)

    Sa, Creso M.

    2011-01-01

    The emerging field of nanotechnology has created a new frontier for the convergence of university and industrial research. In the United States, major federal investments provided a massive boom for this field over the decade. This paper reports on a case study of how the University at Albany came to establish the first college of nanotechnology…

  19. Renegotiating Relations among Teacher, Community, and Students: A Case Study of Teaching Roma Students in a Second Chance Program

    Science.gov (United States)

    Stoilescu, Dorian; Carapanait, Greta

    2011-01-01

    Prejudice and systematic discrimination have often been mentioned as major causes for the chronic underachievement of Roma students. In this paper we present a case study of a Romanian teacher involved in Second Chance, an educational program implemented in Romania in 2004 for the benefit of disadvantaged groups such as the Roma population. Since…

  20. Making a difference: Ten case studies of DSM/IRP interactive efforts and related advocacy group activities

    Energy Technology Data Exchange (ETDEWEB)

    English, M.; Schexnayder, S.; Altman, J. [Tennessee Univ., Knoxville, TN (United States). Energy, Environment and Resources Center; Schweitzer, M. [Oak Ridge National Lab., TN (United States)

    1994-03-01

    This report discusses the activities of organizations that seek to promote integrated resource planning and aggressive, cost-effective demand-side management by utilities. The activities of such groups -- here called energy efficiency advocacy groups (EEAGs) -- are examined in ten detailed am studies. Nine of the cases involve some form of interactive effort between investor-owned electric utilities and non-utility to develop policies, plans, or programs cooperatively. Many but not all of the interactive efforts examined are formal collaboratives. In addition, all ten cases include discussion of other EEAG activities, such as coalition-building, research, participation in statewide energy planning, and intervention in regulatory proceedings.

  1. Estimating risks and relative risks in case-base studies under the assumptions of gene-environment independence and Hardy-Weinberg equilibrium.

    Science.gov (United States)

    Chui, Tina Tsz-Ting; Lee, Wen-Chung

    2014-01-01

    Many diseases result from the interactions between genes and the environment. An efficient method has been proposed for a case-control study to estimate the genetic and environmental main effects and their interactions, which exploits the assumptions of gene-environment independence and Hardy-Weinberg equilibrium. To estimate the absolute and relative risks, one needs to resort to an alternative design: the case-base study. In this paper, the authors show how to analyze a case-base study under the above dual assumptions. This approach is based on a conditional logistic regression of case-counterfactual controls matched data. It can be easily fitted with readily available statistical packages. When the dual assumptions are met, the method is approximately unbiased and has adequate coverage probabilities for confidence intervals. It also results in smaller variances and shorter confidence intervals as compared with a previous method for a case-base study which imposes neither assumption.

  2. Acoustic neuroma risk in relation to mobile telephone use: Results of the INTERPHONE international case-control study

    DEFF Research Database (Denmark)

    Berg-Beckhoff, Gabi

    2011-01-01

    Background: The rapid increase in mobile telephone use has generated concern about possible health risks of radiofrequency electromagnetic fields from these devices. Methods: A case-control study of 1105 patients with newly diagnosed acoustic neuroma (vestibular schwannoma) and 2145 controls...... was conducted in 13 countries using a common protocol. Past mobile phone use was assessed by personal interview. In the primary analysis, exposure time was censored at one year before the reference date (date of diagnosis for cases and date of diagnosis of the matched case for controls); analyses censoring...... exposure at five years before the reference date were also done to allow for a possible longer latent period. Results: The odds ratio (OR) of acoustic neuroma with ever having been a regular mobile phone user was 0.85 (95% confidence interval 0.69-1.04). The OR for ≥10 years after first regular mobile...

  3. Strategic Factors in the Choice of a Model of Public Relations. Case Study: Seventh-day Adventist Church World Headquarters.

    Science.gov (United States)

    Denton, Holly M.

    A study tested a model of organizational variables that earlier research had identified as important in influencing what model(s) of public relations an organization selects. Models of public relations (as outlined by J. Grunig and Hunt in 1984) are defined as either press agentry, public information, two-way asymmetrical, or two-way symmetrical.…

  4. How physics teachers approach innovation: An empirical study for reconstructing the appropriation path in the case of special relativity

    OpenAIRE

    Anna De Ambrosis; Olivia Levrini

    2010-01-01

    This paper concerns an empirical study carried out with a group of high school physics teachers engaged in the Module on relativity of a Master course on the teaching of modern physics. The study is framed within the general research issue of how to promote innovation in school via teachers’ education and how to foster fruitful interactions between research and school practice via the construction of networks of researchers and teachers. In the paper, the problems related to innovation are ad...

  5. Cervical Spine Immobilization in Sports Related Injuries: Review of Current Guidelines and a Case Study of an Injured Athlete

    OpenAIRE

    Bhamra, JS; Morar, Y; Khan, WS; Deep, K.; Hammer, A.

    2012-01-01

    Cervical spine immobilization is an essential component of the ATLS® system. Inadequate training in the management of trauma calls and failure of early recognition can have disastrous consequences. Pre-hospital personnel are routinely involved more in the assessment and stabilization of patients in comparison to other health care professionals. This case study and review highlights the importance of early recognition, assessment and correct stabilization of cervical spine injuries both in the...

  6. The Teacher and the Community: A Case Study of Teacher-Community Relations among the Zapotec and Mixtec Indians of Oaxaca, Mexico.

    Science.gov (United States)

    Densmore, Kathleen

    1998-01-01

    Studies teacher-community relations in a community where teachers are becoming more involved in indigenous community issues. Argues that formal teacher education tends to emphasize modernity and consumer culture at the expense of distinct local customs. Draws connections between the case study and low-income minority communities in the United…

  7. How Physics Teachers Approach Innovation: An Empirical Study for Reconstructing the Appropriation Path in the Case of Special Relativity

    Science.gov (United States)

    De Ambrosis, Anna; Levrini, Olivia

    2010-01-01

    This paper concerns an empirical study carried out with a group of high school physics teachers engaged in the Module on relativity of a Master course on the teaching of modern physics. The study is framed within the general research issue of how to promote innovation in school via teachers' education and how to foster fruitful interactions…

  8. Case study research.

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    Taylor, Ruth; Thomas-Gregory, Annette

    2015-06-10

    This article describes case study research for nursing and healthcare practice. Case study research offers the researcher an approach by which a phenomenon can be investigated from multiple perspectives within a bounded context, allowing the researcher to provide a 'thick' description of the phenomenon. Although case study research is a flexible approach for the investigation of complex nursing and healthcare issues, it has methodological challenges, often associated with the multiple methods used in individual studies. These are explored through examples of case study research carried out in practice and education settings. An overview of what constitutes 'good' case study research is proposed.

  9. Towards a semantic framework for an integrative description of neuroscience patterns and studies: a case for emotion-related data.

    Science.gov (United States)

    Bratsas, Charalampos; Frantzidis, Christos A; Klados, Manousos; Papadelis, Christos; Pappas, Costas; Bamidis, Panagiotis D

    2009-01-01

    The continuously increasing number of neuroscience studies and the difficulties associated with searching for related information and properly tracking neuroscience findings makes it imperative that one may be lead to isolated theories and findings which may be incompatible to each other or partially occluded. Semantically describing several aspects of studies in this field, such as, research groups attributes, aims of studies, experimental procedures followed, hardware and software tools utilised, acquisition systems used, as well as, the emerging neuro-physiological patterns found, may facilitate an integrative view of neuroscience theories. To this end, the current piece of work aims to provide a global theoretical framework using ontologies and semantic rules to describe neuroscience studies. Implementation details and applicability of the proof of concept are illustrated by means of an example targeting the semantic description of an emotion related study. The importance of the proposed framework in facilitating the envisaged personalised healthcare of the information society is discussed.

  10. SWOT Analysis of Strategic Position of Sport and Youth Ministry`s Public Relations Department in Iran: A Case Study

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    Saeid Ali Abadi

    2012-08-01

    Full Text Available The aim of the present study was to design sports and youth ministry`s public relations department strategic plan .This research was survey research done in analytical method and the method of collecting data was field study. In terms of objective, it is an applied - developmental research in which the required information was obtained through library research and the researcher-made questionnaire. Also, this research was of strategic studies in which the qualitative and quantitative methods were used for data analysis. Statistical population included sports media managers and journalists, public relations directors of the sports federations, sport management professionals, staff specialists of the Ministry of Sport and National Olympic Committee and public relations staff consisting of 144 persons as the study sample. In this study, a questionnaire in two parts was used that included demographic data and determination of the strengths, weaknesses, threats and opportunities of Department of public relations in Youth and Sports ministry. To determine its validity, professors and experts were consulted and after applying all revised recommendations and changes necessary to comply with the conditions and characteristics of the study population, it was used, accordingly. Cronbach's alpha coefficient was used to measure the reliability. Therefore, Cronbach's alpha reliability was obtained 0.99. Coefficient obtained from the questionnaire indicated high reliability of the questionnaire. In data analysis, descriptive statistics was used to describe demographic variables in the research community. Friedman rank test was used for ranking the strengths, weaknesses, opportunities and threats. Finally, SWOT analysis was used for developing the Ministry of Youth and Sports ministry`s public relations department`s strategy. The results indicated that the scores sum in this matrix was less than 2.5 (2.42.This suggested that it was weak in terms of internal

  11. Strategies Formulation for Sports and Youth Ministry`s Public Relations Department in Iran: A Case Study

    Directory of Open Access Journals (Sweden)

    Saeid Ali Abadi

    2012-08-01

    Full Text Available The aim of the present study was to design sports and youth ministry`s public relations department strategic plan .This research was survey research done in analytical method and the method of collecting data was field study. In terms of objective, it is an applied - developmental research in which the required information was obtained through library research and the researcher-made questionnaire. Also, this research was of strategic studies in which the qualitative and quantitative methods were used for data analysis. Statistical population included sports media managers and journalists, public relations directors of the sports federations, sport management professionals, staff specialists of the Ministry of Sport and National Olympic Committee and public relations staff consisting of 144 persons as the study sample. In this study, a questionnaire in two parts was used that included demographic data and determination of the strengths, weaknesses, threats and opportunities of Department of public relations in Youth and Sports ministry. To determine its validity, professors and experts were consulted and after applying all revised recommendations and changes necessary to comply with the conditions and characteristics of the study population, it was used, accordingly. Cronbach's alpha coefficient was used to measure the reliability. Therefore, Cronbach's alpha reliability was obtained 0.99. Coefficient obtained from the questionnaire indicated high reliability of the questionnaire. In data analysis, descriptive statistics was used to describe demographic variables in the research community. Friedman rank test was used for ranking the strengths, weaknesses, opportunities and threats. Finally, SWOT analysis was used for developing the Ministry of Youth and Sports ministry`s public relations department`s strategy. The results indicated that the scores sum in this matrix was less than 2.5 (2.42.This suggested that it was weak in terms of internal

  12. Cognitive bias salience in patients with schizophrenia in relation to social functioning: A four-case observation study.

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    Gurovich, Isaac Ya; Papsuev, Oleg O; Shmukler, Alexander B; Movina, Larisa G; Storozhakova, Yanina A; Kiryanova, Elena M

    2016-03-01

    Neurocognition and social cognition are the core deficits influencing social outcomes in patients with schizophrenia. These deficits are present in the prodromal phase, throughout the illness and in first-degree relatives. They are considered in the framework of neurodevelopmental or neurodegenerative models as well as candidates for endophenotypes of schizophrenia. Four clinical cases with patients reflecting different cognitive profiles were chosen to demonstrate heterogeneity of cognitive biases and their influence on social function in vivo. The patients had undergone a number of neurocognitive and social cognitive measures. Better functioning was observed in patients with less affected domains of emotional processing and theory of mind, while neurocognitive statuses were incongruent to levels of social functioning. Further investigation on large samples concerning capacity for empathy and its role in social functioning is needed.

  13. How physics teachers approach innovation: An empirical study for reconstructing the appropriation path in the case of special relativity

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    Anna De Ambrosis

    2010-08-01

    Full Text Available This paper concerns an empirical study carried out with a group of high school physics teachers engaged in the Module on relativity of a Master course on the teaching of modern physics. The study is framed within the general research issue of how to promote innovation in school via teachers’ education and how to foster fruitful interactions between research and school practice via the construction of networks of researchers and teachers. In the paper, the problems related to innovation are addressed by focusing on the phase during which teachers analyze an innovative teaching proposal in the perspective of designing their own paths for the class work. The proposal analyzed in this study is Taylor and Wheeler’s approach for teaching special relativity. The paper aims to show that the roots of problems known in the research literature about teachers’ difficulties in coping with innovative proposals, and usually related to the implementation process, can be found and addressed already when teachers approach the proposal and try to appropriate it. The study is heuristic and has been carried out in order to trace the “appropriation path,” followed by the group of teachers, in terms of the main steps and factors triggering the progressive evolution of teachers’ attitudes and competences.

  14. University Students' Knowledge of Services and Programs in Relation to Satisfaction: A Case Study of a Private University in Lebanon

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    Nasser, Ramzi N.; Khoury, Bechara; Abouchedid, Kamal

    2008-01-01

    Purpose: The purpose of this paper is to survey students on their satisfaction with university services and programs in a coeducational Lebanese Catholic higher education institution. The study attempts to relate self-assessed knowledge of the university procedures, rules and regulations on six dimensions of satisfaction, being: academic…

  15. Work-related psychosocial events as triggers of sick leave - results from a Swedish case-crossover study

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    Lindholm Christina

    2011-03-01

    Full Text Available Abstract Background Although illness is an important cause of sick leave, it has also been suggested that non-medical risk factors may influence this association. If such factors impact on the period of decision making, they should be considered as triggers. Yet, there is no empirical support available. The aim was to investigate whether recent exposure to work-related psychosocial events can trigger the decision to report sick when ill. Methods A case-crossover design was applied to 546 sick-leave spells, extracted from a Swedish cohort of 1 430 employees with a 3-12 month follow-up of new sick-leave spells. Exposure in a case period corresponding to an induction period of one or two days was compared with exposure during control periods sampled from workdays during a two-week period prior to sick leave for the same individual. This was done according to the matched-pair interval and the usual frequency approaches. Results are presented as odds ratios (OR with 95% confidence intervals (CI. Results Most sick-leave spells happened in relation to acute, minor illnesses that substantially reduced work ability. The risk of taking sick leave was increased when individuals had recently been exposed to problems in their relationship with a superior (OR 3.63; CI 1.44-9.14 or colleagues (OR 4.68; CI 1.43-15.29. Individuals were also more inclined to report sick on days when they expected a very stressful work situation than on a day when they were not under such stress (OR 2.27; CI 1.40-3.70. Conclusions Exposure to problems in workplace relationships or a stressful work situation seems to be able to trigger reporting sick. Psychosocial work-environmental factors appear to have a short-term effect on individuals when deciding to report sick.

  16. Case-control study of risk of Parkinson's disease in relation to hypertension, hypercholesterolemia, and diabetes in Japan.

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    Miyake, Yoshihiro; Tanaka, Keiko; Fukushima, Wakaba; Sasaki, Satoshi; Kiyohara, Chikako; Tsuboi, Yoshio; Yamada, Tatsuo; Oeda, Tomoko; Miki, Takami; Kawamura, Nobutoshi; Sakae, Nobutaka; Fukuyama, Hidenao; Hirota, Yoshio; Nagai, Masaki

    2010-06-15

    This case-control study investigated the associations of a history of hypertension, hypercholesterolemia, and diabetes mellitus with the risk of Parkinson's disease (PD) in Japan. Included were 249 cases within 6 years of onset of PD. Controls were 368 inpatients and outpatients without a neurodegenerative disease. Data on the vascular risk factors and confounders were obtained from a self-administered questionnaire. The vascular risk factors were defined based on drug treatment. Adjustment was made for sex, age, region of residence, pack-years of smoking, years of education, leisure-time exercise, body mass index, dietary intake of energy, cholesterol, vitamin E, alcohol, and coffee and the dietary glycemic index. The proportions of hypertension, hypercholesterolemia, and diabetes mellitus prior to the onset of PD were 23.7%, 9.6%, and 4.0%, respectively, in cases. Hypertension, hypercholesterolemia, and diabetes mellitus were significantly associated with a decreased risk of PD: the adjusted ORs were 0.43 (95% CI: 0.29-0.64), 0.58 (95% CI: 0.33-0.97), and 0.38 (95% CI: 0.17-0.79), respectively. No significant differences were observed in the association of vascular risk factors with the risk of PD between men and women. We found evidence of significant inverse associations of hypertension, hypercholesterolemia, and diabetes mellitus with the risk of PD in Japan. Further well-designed investigations of the association of vascular risk factors with the risk of PD are needed, particularly large-scale prospective studies in Asia.

  17. Relative influence of chemical and non-chemical stressors on invertebrate communities: a case study in the Danube River.

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    Rico, Andreu; Van den Brink, Paul J; Leitner, Patrick; Graf, Wolfram; Focks, Andreas

    2016-11-15

    A key challenge for the ecological risk assessment of chemicals has been to evaluate the relative contribution of chemical pollution to the variability observed in biological communities, as well as to identify multiple stressor groups. In this study we evaluated the toxic pressure exerted by >200 contaminants to benthic macroinvertebrates in the Danube River using the Toxic Unit approach. Furthermore, we evaluated correlations between several stressors (chemical and non-chemical) and biological indices commonly used for the ecological status assessment of aquatic ecosystems. We also performed several variation partitioning analyses to evaluate the relative contribution of contaminants and other abiotic parameters (i.e. habitat characteristics, hydromorphological alterations, water quality parameters) to the structural and biological trait variation of the invertebrate community. The results of this study show that most biological indices significantly correlate to parameters related to habitat and physico-chemical conditions, but showed limited correlation with the calculated toxic pressure. The calculated toxic pressure, however, showed little variation between sampling sites, which complicates the identification of pollution-induced effects. The results of this study show that the variation in the structure and trait composition of the invertebrate community are mainly explained by habitat and water quality parameters, whereas hydromorphological alterations play a less important role. Among the water quality parameters, physico-chemical parameters such as suspended solids, nutrients or dissolved oxygen explained a larger part of the variation in the invertebrate community as compared to metals or organic contaminants. Significant correlations exist between some physico-chemical measurements (e.g. nutrients) and some chemical classes (i.e. pharmaceuticals, chemicals related to human presence) which constitute important multiple stressor groups. This study

  18. GLOBALIZATION AND RESPONSE OF LARGE STATED OWNED ENTERPRISES IN AGRICULTURAL RELATED INDUS TRIES: COMPANY CASE STUDIES FROM CENTRAL CHINA

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    By using interview data from three large state-owned enterprises (SOEs) in agriculture related industries, this paper reveals that SOEs in inland area are much slow in response to globalization. Although they pursued some strate gies to adjust themselves, they are far behind the position to utilize the opportunities generated by economic globaliza tion. Most of them are still out of the networks of transnational corporations. The strategies they adopted are quite differ ent from SOEs in the coastal area. They overlook the importance of information infrastructure, well-educated personnel, and collaboration with the competitive leaders in their industries. The lagging situation is related to isolated location, tradi tional culture, and slow progress in enterprise reform. International comparison shows that the case companies did follow the general patterns that globalization promotes extension of company′s networks of linkages but in a rather slow phase. The decision makers should encourage intra-regional linkages between SOEs, between SOEs and private, foreign owned companies, as well as inter-regional linkages among them. The latter appears particularly important given the enlarging gaps between coastal and inland areas.

  19. Integrating Best Practices in Positive Behavior Support and Clinical Psychology for a Child with Autism and Anxiety-Related Problem Behavior: A Clinical Case Study

    Science.gov (United States)

    Neufeld, Vanessa; Law, Kimberley C. Y.; Lucyshyn, Joseph M.

    2014-01-01

    This clinical case study investigated the effectiveness of a multicomponent intervention for a child with autism and anxiety-related problem behavior that integrated components of cognitive behavior therapy (CBT) with positive behavior support (PBS). One child with autism and his family participated. The dependent variable was the number of steps…

  20. Analisys of the corpotative education related with the mision of the organization: a case study of SENAC/SC

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    Sirlene Silveira de Amorim

    2008-05-01

    Full Text Available This work has as objective to verify if the programs of corporative education offered by SENAC/SC for yours emploies make easier the fulfillment of their mission. It consists of a descriptive, exploration and applied case study, whose the boarding is qualitative and it uses techniques of observation direct intensive, presenting as way the field research, documentary inquiry and research of bibliography. In the end of the case study it was evidenced that inexist a work directed for the corporative education, it hasn’t much organization around the referring subjects to the development of people and inexist yet a strategical vision around the human potencial connected to the possible success of the organization. This situation, add up to the not-connect of the theme corporative education with the strategical planning of the institution, permit verify that the programs of corporative education don’t make easier the fulfillment of their mission, once that are not directed to the emploies.

  1. Modeling effects of urban heat island mitigation strategies on heat-related morbidity: a case study for Phoenix, Arizona, USA.

    Science.gov (United States)

    Silva, Humberto R; Phelan, Patrick E; Golden, Jay S

    2010-01-01

    A zero-dimensional energy balance model was previously developed to serve as a user-friendly mitigation tool for practitioners seeking to study the urban heat island (UHI) effect. Accordingly, this established model is applied here to show the relative effects of four common mitigation strategies: increasing the overall (1) emissivity, (2) percentage of vegetated area, (3) thermal conductivity, and (4) albedo of the urban environment in a series of percentage increases by 5, 10, 15, and 20% from baseline values. In addition to modeling mitigation strategies, we present how the model can be utilized to evaluate human health vulnerability from excessive heat-related events, based on heat-related emergency service data from 2002 to 2006. The 24-h average heat index is shown to have the greatest correlation to heat-related emergency calls in the Phoenix (Arizona, USA) metropolitan region. The four modeled UHI mitigation strategies, taken in combination, would lead to a 48% reduction in annual heat-related emergency service calls, where increasing the albedo is the single most effective UHI mitigation strategy.

  2. Shifts in indigenous culture relate to forest tree diversity: a case study from the Tsimane’, Bolivian Amazon

    Science.gov (United States)

    Guèze, Maximilien; Luz, Ana Catarina; Paneque-Gálvez, Jaime; Macía, Manuel J.; Orta-Martínez, Martí; Pino, Joan; Reyes-García, Victoria

    2015-01-01

    Understanding how indigenous peoples’ management practices relate to biological diversity requires addressing contemporary changes in indigenous peoples’ way of life. This study explores the association between cultural change among a Bolivian Amazonian indigenous group, the Tsimane’, and tree diversity in forests surrounding their villages. We interviewed 86 informants in six villages about their level of attachment to traditional Tsimane’ values, our proxy for cultural change. We estimated tree diversity (Fisher’s Alpha index) by inventorying trees in 48 0.1-ha plots in old-growth forests distributed in the territory of the same villages. We used multivariate models to assess the relation between cultural change and alpha tree diversity. Cultural change was associated with alpha tree diversity and the relation showed an inverted U-shape, thus suggesting that tree alpha diversity peaked in villages undergoing intermediate cultural change. Although the results do not allow for testing the direction of the relation, we propose that cultural change relates to tree diversity through the changes in practices and behaviors that affect the traditional ecological knowledge of Tsimane’ communities; further research is needed to determine the causality. Our results also find support in the intermediate disturbance hypothesis, and suggest that indigenous management can be seen as an intermediate form of anthropogenic disturbance affecting forest communities in a subtle, non-destructive way. PMID:26097240

  3. Shifts in indigenous culture relate to forest tree diversity: a case study from the Tsimane', Bolivian Amazon.

    Science.gov (United States)

    Guèze, Maximilien; Luz, Ana Catarina; Paneque-Gálvez, Jaime; Macía, Manuel J; Orta-Martínez, Martí; Pino, Joan; Reyes-García, Victoria

    2015-06-01

    Understanding how indigenous peoples' management practices relate to biological diversity requires addressing contemporary changes in indigenous peoples' way of life. This study explores the association between cultural change among a Bolivian Amazonian indigenous group, the Tsimane', and tree diversity in forests surrounding their villages. We interviewed 86 informants in six villages about their level of attachment to traditional Tsimane' values, our proxy for cultural change. We estimated tree diversity (Fisher's Alpha index) by inventorying trees in 48 0.1-ha plots in old-growth forests distributed in the territory of the same villages. We used multivariate models to assess the relation between cultural change and alpha tree diversity. Cultural change was associated with alpha tree diversity and the relation showed an inverted U-shape, thus suggesting that tree alpha diversity peaked in villages undergoing intermediate cultural change. Although the results do not allow for testing the direction of the relation, we propose that cultural change relates to tree diversity through the changes in practices and behaviors that affect the traditional ecological knowledge of Tsimane' communities; further research is needed to determine the causality. Our results also find support in the intermediate disturbance hypothesis, and suggest that indigenous management can be seen as an intermediate form of anthropogenic disturbance affecting forest communities in a subtle, non-destructive way.

  4. Case Study - Alpha

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    Stephen Leybourne

    2016-11-01

    Full Text Available This case study was developed from an actual scenario by Dr. Steve Leybourne of Boston University.  The case documents the historical evolution of an organization, and has been used successfully in courses dealing with organizational and cultural change, and the utilization of ‘soft skills’ in project-based management. This is a short case, ideal for classroom use and discussion.  The issues are easily accessible to students, and there is a single wide ranging question that allows for the inclusion of many issues surrounding strategic decision-making, and behavioural and cultural change. Alpha was one of the earlier companies in the USA to invest in large, edge-of-town superstores, with plentiful free vehicle parking, selling food and related household products. Alpha was created in the 1950s as a subsidiary of a major publicly quoted retail group.  It started business by opening a string of very large discount stores in converted industrial and warehouse premises in the south of the United States. In the early days shoppers were offered a limited range of very competitively priced products. When Alpha went public in 1981 it was the fourth largest food retailer in the US, selling an ever-widening range of food and non-food products.  Its success continued to be based on high volume, low margins and good value for money, under the slogan of ‘Alpha Price.’

  5. Cochlear Implantation through the Middle Fossa Approach: A Review of Related Temporal Bone Studies and Reported Cases.

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    Lesser, Juan Carlos Cisneros; Brito Neto, Rubens Vuono de; Martins, Graziela de Souza Queiroz; Bento, Ricardo Ferreira

    2017-01-01

    Introduction Middle fossa approach has been suggested as an alternative for patients in whom other routes of electrode insertion are contraindicated. Even though there are temporal bone studies about the feasibility of introducing the cochlear implant through the middle fossa, until now, very few studies have described results when cochlear implant surgery is done through this approach. Objective The objective of this study is to review a series of temporal bone studies related to cochlear implantation through the middle fossa and the results obtained by different surgical groups after cochlear implantation through this approach. Data Sources PubMed, MD consult and Ovid-SP databases. Data Synthesis A total of 8 human cadaveric temporal bone studies and 6 studies reporting cochlear implant surgery through the middle fossa approach met the inclusion criteria. Temporal bone studies show that it is feasible to perform cochlear implantation through this route. So far, only two surgical groups have performed cochlear implantation through the middle fossa with a total of 15 implanted patients. One group entered the cochlea in the most upper part of the basal turn, inserting the implant in the direction of the middle and apical turns; meanwhile, the other group inserted the implant in the apical turn directed in a retrograde fashion to the middle and basal turns. Results obtained in both groups were similar. Conclusions The middle fossa approach is a good alternative for cochlear implantation when other routes of electrode insertion are contraindicated.

  6. Can even minimal news coverage influence consumer health-related behaviour? A case study of iodized salt sales, Australia.

    Science.gov (United States)

    Li, Mu; Chapman, Simon; Agho, Kingsley; Eastman, Creswell J

    2008-06-01

    Lack of iodine in the diet can cause a spectrum of conditions, known as iodine deficiency disorders (IDD). While iodized salt has been retailed in Australia since the 1960s, sales have remained low, at approximately 10% of total edible salt sales. Salt has never been promoted, advertised or discounted by retailers or manufacturers. Extensive news coverage of health issues has often been shown to influence consumer behaviour. But can even modest news coverage generate changes in consumer health-related behaviour? We report a significant increase (5.2%) in national iodized salt sales after a brief period of television and newspaper reports about IDD and the benefits of using iodized salt during and after the Australian National Iodine Nutrition Study in 2003 and 2004. We conclude that even brief news media exposure can influence health-related decisions.

  7. Are local plague endemicity and ecological characteristics of vectors and reservoirs related? A case study in north-east Tanzania

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    Herwig LEIRS

    2009-06-01

    Full Text Available The pattern of plague endemicity in Tanzania is characterized by continuous re-appearance of the disease in some locations, while in other neighbouring villages the disease has never or seldom been observed. To understand the reasons for this pattern, we studied small mammals and fleas species composition, diversity and relative abundances in two plague-endemic and two plague-free locations. We asked (a whether fleas more abundant in plague-endemic locations differ in their characteristic abundance and the degree of their host specificity from fleas most abundant in plague-free locations and (b whether hosts more abundant in plague-endemic locations differ in the diversity of their flea assemblages from hosts most abundant in plague-free locations. We characterized (a host species by species richness and degree of taxonomic relatedness of its flea assemblages and (b each flea species by its mean abundance and size, and degree of taxonomic relatedness of its host spectrum and compared their relative abundances between locations. No significant difference between plague-endemic and plague-free locations in either host density or any variable related to flea abundance or diversity was found. However, there was marginally significant effect of taxonomic distinctness of a flea assemblage harboured by a host on its probability to be more abundant in either plague-endemic or plague-free locations. Furthermore, hosts more abundant in plague-endemic locations tended to harbour closely-related fleas. Finally, while opportunistic and specialist fleas were equally distributed in both sets of locations, fleas exploiting distantly-related hosts were found mainly in plague-free locations during the rainy season. We suggest that the observed patterns might arise due to seasonal and spatial differences in local microclimatic conditions and landscape connectivity[Current Zoology 55(3:199–211, 2009].

  8. Are local plague endemicity and ecological characteristics of vectors and reservoirs related? A case study in north-east Tanzania

    Institute of Scientific and Technical Information of China (English)

    Anne LAUDISOIT; Simon NEERINCKX; Rhodes H.MAKUNDI; Herwig LEIRS; Boris R.KRASNOV

    2009-01-01

    The pattern of plague endemicity in Tanzania is characterized by continuous re-appearance of the disease in some locations, while in other neighbouring villages the disease has never or seldom been observed. To understand the reasons for this pattern, we studied small mammal and flea species composition, diversity and relative abundances in two plague-endemic and two plague-free locations. We asked (a) whether fleas more abundant in plague-endemic locations differ in their characteristic abundance and the degree of their host specificity from fleas more abundant in plague-free locations and (b) whether hosts most abundant in plagne-endemic locations differ in the diversity of their flea assemblages from hosts most abundant in plague-free locations. We characterized (a) each host species by species richness and degree of taxonomic relatedness of its flea assemblages and (b) each flea species by its mean abundance and size, and degree of taxonomic relatedness of its host spectrum and compared their relative abundances between locations. No significant difference between plague-endemic and plague-free locations in either host density or any variable related to flea abundance or diversity was found. However, there was marginally significant effect of taxonomic distinctness of a flea assemblage harboured by a host on its probability to be more abundant in either plague-endemic or plague-free locations. Furthermore, hosts more abundant in plague-endemic locations tended to harbeur closely-related fleas. Finally, while opportunistic and specialist fleas were equally distributed in both sets of locations, fleas exploiting distantly-related hosts were found mainly in plague-free locations during the rainy season. We suggest that the observed patterns might arise due to seasonal and spatial differences in local microclimatic conditions and landscape connectivity.

  9. The relation between serum lipids and lutein and zeaxanthin in the serum and retina: results from cross-sectional, case-control and case study designs

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    Renzi Lisa M

    2012-02-01

    Full Text Available Abstract Background The xanthophyll carotenoids lutein (L and zeaxanthin (Z are found in and around the macula of the primate retina, where they are termed macular pigment (MP. Dietary L and Z are absorbed with fat in the gut and transported on lipoproteins to the retina. Both MP and serum lipoproteins have been related to risk for neurodegenerative diseases such as age-related macular degeneration (AMD. L and Z are carried on both HDL (related to reduced risk of AMD and LDL (related to increased risk. The purpose of this set of studies was to analyze the relation between L and Z in the serum and retina with the circulating lipid profile. Methods In all experiments, lipoproteins were measured enzymatically from plasma, and MP optical density (MPOD was measured using customized heterochromatic flicker photometry. Experiment 1: Relations between serum L and Z, MPOD and lipoprotein levels. 108 young, healthy subjects (M = 23.2, SD = 4.12 years participated. Lipoprotein levels and MPOD were measured. In a subset of 66 participants, serum L and Z levels were also measured using high-performance liquid chromatography. Experiment 2: Relations between lipoprotein levels and MPOD in statin users. 20 subjects (M = 58.05, SD = 11.08 years taking statin medication and 20 subjects (M = 57.95, SD = 11.03 years not taking satin were recruited for participation. MPOD and lipoprotein levels were measured. Experiment 3: lowering lipoprotein levels to impact MPOD. One individual (aged 41 years with high MP density adhered first to an atorvastatin regimen, then, after a wash-out period, to a rosuvastatin regimen. Results Experiment 1: HDL were significantly (p r = 0.33, to serum L (r = 0.36 and to serum Z (r = 0.26. MPOD was also significantly related to total cholesterol (r = 0.19. Experiment 2: MPOD was not lower in statin users when compared to matched non-statin users, but MPOD decreased significantly with increased duration of statin use (r = −0

  10. Double disadvantage: a case control study on health-related quality of life in children with sickle cell disease

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    Heijboer Harriët

    2010-10-01

    Full Text Available Abstract Background Low health-related quality of life (HRQoL of children with sickle cell disease (SCD may be associated with consequences of the disease, or with the low socio-economic status (SES of this patient population. The aim of this study was to investigate the HRQoL of children with SCD, controlling for SES by comparing them to healthy siblings (matched for age and gender, and to a Dutch norm population. Methods The HRQoL of 40 children with homozygous SCD and 36 healthy siblings was evaluated by the KIDSCREEN-52. This self-report questionnaire assesses ten domains of HRQoL. Differences between children with SCD and healthy siblings were analyzed using linear mixed models. One-sample t-tests were used to analyze differences with the Dutch norm population. Furthermore, the proportion of children with SCD with impaired HRQoL was evaluated. Results In general, the HRQoL of children with SCD appeared comparable to the HRQoL of healthy siblings, while children with SCD had worse HRQoL than the Dutch norm population on five domains (Physical Well-being, Moods & Emotions, Autonomy, Parent Relation, and Financial Resources. Healthy siblings had worse HRQoL than the Dutch norm population on three domains (Moods & Emotions, Parent Relation, and Financial Resources. More than one in three children with SCD and healthy siblings had impaired HRQoL on several domains. Conclusion These findings imply that reduced HRQoL in children with SCD is mainly related to the low SES of this patient population, with the exception of disease specific effects on the physical and autonomy domain. We conclude that children with SCD are especially vulnerable compared to other patient populations, and have special health care needs.

  11. Pregnancy-related systemic lupus erythematosus: clinical features, outcome and risk factors of disease flares--a case control study.

    Directory of Open Access Journals (Sweden)

    Huaxia Yang

    Full Text Available OBJECTIVE: To investigate the clinical features, outcome, and risk factors of disease flares in patients with pregnancy-related lupus (PRL. METHODS: Medical charts of 155 consecutive PRL inpatients were systematically reviewed, including demographic data, clinical features, laboratory findings, treatment, complications, and outcome. RESULTS: PRL cases were divided into active (a-PRL (n = 82, 53.0% and stable lupus (s-PRL (n = 73, 47.0%. Compared with nonpregnant active female systemic lupus erythematosus (SLE patients, a-PRL including new-onset lupus (n-PRL and flare lupus (f-PRL (n = 41 respectively, had a higher incidence of renal and hematological involvement but less mucocutaneous and musculoskeletal involvement (p<0.05. The incidence of preeclampsia/eclampsia, fetal loss, and preterm birth were significantly higher in a-PRL than in s-PRL (p<0.05. Despite receiving a more vigorous glucocorticoid treatment, a-PRL mothers had a poorer prognosis (p<0.001. Five (6.1% of them died and 13 (15.9% developed severe irreversible organ failure, whereas none of these events was observed in the s-PRL group. Multivariate logistic analysis indicated that a history of lupus flares and serological activity (hypocomplementemia and/or anti-dsDNA positivity at the time of conception were associated with lupus flares in PRL mothers. CONCLUSIONS: SLE patients with a flare history and serological activity at the time of conception were at an increased risk of disease flares during pregnancy and puerperium. a-PRL patients were more prone to renal and hematological involvement, pregnancy complications, and a poorer prognosis despite more vigorous glucocorticoid treatment.

  12. An investigation of somatosensory profiles in work related upper limb disorders: a case-control observational study protocol.

    LENUS (Irish Health Repository)

    Moloney, Niamh

    2010-01-01

    BACKGROUND: Work related upper limb disorders constitute 45% of all occupational diseases and are a significant public health problem. A subgroup, non specific arm pain (NSAP), remains elusive in terms of understanding its pathophysiological mechanisms with its diagnosis based on the absence of specific clinical findings. One commonly proposed theory is that a neural tissue disorder is the primary dysfunction in NSAP and findings from previous studies lend some support to this theory. However, it is not clear if changes identified are simply a consequence of ongoing pain rather than due to specific neural changes. The presence of neuropathic pain has been investigated in several other musculoskeletal conditions but currently, there is no specific diagnostic tool or gold standard which permits an unequivocal diagnosis of neuropathic pain. The purpose of this study is to further describe the somatosensory profiles in patients with NSAP and to compare these profiles to a group of patients with MRI confirmed cervical radiculopathy who have been previously classified as having neuropathic pain. METHODS\\/DESIGN: Three groups of participants will be investigated: Groups 1 and 2 will be office workers with either NSAP or cervical radiculopathy and Group 3 will be a control group of non office workers without upper limb pain. Participants will undergo a clinical assessment, pain questionnaires (LANSS, Short Form McGill, DASH and TSK) and quantitative sensory testing comprising thermal detection and pain thresholds, vibration thresholds and pressure pain thresholds. DISCUSSION: The spectrum of clinically suspected neuropathic pain ranges from more obvious conditions such as trigeminal neuralgia to those with vague signs of nerve disorder such as NSAP. A thorough description of the somatosensory profiles of NSAP patients and a comparison with a more defined group of patients with evidence of neuropathic pain will help in the understanding of underlying neurophysiology in

  13. GLOBALIZATION AND RESPONSE OF LARGE STATED OWNED ENTERPRISES IN AGRICULTURAL RELATED INDUS TRIES: COMPANY CASE STUDIES FROM CENTRAL CHINA

    Institute of Scientific and Technical Information of China (English)

    LI; Xiao-jian

    2001-01-01

    [1]AMIN A, THRIFT N, 1994. Globalization, Institutions, and Regional Development in Europe [M]. Oxford: Oxford University Press.[2]CHEN A, 1998. Inertia in reforming China′s state-owned enterprises: the case of Chongqing [J]. World Development, 26(3): 479-495.[3]CFTGC (China First Tractor Group Co. Ltd. ), 2000. A Report of the Impact of China′s Entry to WTO on CFTGC [R] . CFFGC.[4]DICKEN P, 1998. Global Shift: Transforming the World Economy [M]. 3rd ed. London: Paul Chapman Publishing Ltd.[5]DONG Fu-reng, TANG Zong-kun, DU Hai-yan eds., 1995. Institutional Reform of China′ s Stated Owned Enterprises [M].Beijing: People′s Press. (in Chinese)[6]HARLAND C M, 1995. Networks and Globalization: A Review of Research [M]. Warwick Business School, University of Warwick.[7]HIRSCHMAN A O, 1958. The Strategy of Economic Development [M]. Yale University Press, New Haven.[8]LI Shan-tong, ZAI Fan, XU Lin, 2000. Impact on China′s economy after membership of WTO [J]. World Economy 2:3-14.[9]LI Wen-yan, LU Da-dao (eds.), 1995. Industrial Geography of China [M]. Beijing and New York: Science Press.[10]LI Xiao-jian, 1998: Enterprise reform and its impact on regional development: the ease of Henan Province [J]. Economic Geography 18(3): 1-6. (in Chinese)[11]LI Xiao-jian, 1999. Foreign direct investment and its impact on economic development of Coastal China [J]. Acta Geographica Sinica, 54(5): 420-430. (in Chinese)[12]LI Xiao-jian, 2000. Institutional reform of state-owned enterprises. In: LU Da-dao et al. (ed.). China Regional Development Report 1999 [C]. Beijing: Commercial Press. (in Chinese)[13]LI Xiao-jian, YEUNG Y M, 1998. Transnational corporations and theirimpact onregional economi cdevelopment: evidence from China [J]. Third World Planning Reviem 20(4): 351-373.[14]LI Xiao-jian, YEUNG Y M, 1999. Inter-firm linkages and regional impact of transnational corporations: company case studies from Shanghai, China [J

  14. Båth's law and its relation to the tectonic environment: A case study for earthquakes in Mexico

    Science.gov (United States)

    Rodríguez-Pérez, Q.; Zúñiga, F. R.

    2016-09-01

    We studied 66 mainshocks and their largest aftershocks in the Mexican subduction zone and in the Gulf of California with magnitudes in the range of 5.2 energy ratios and energy partitioning of the mainshock-largest aftershock sequences, we analyze the physics of the mainshock-largest aftershock relationship (Båth's law). The partitioning of energy during a mainshock-aftershock sequence shows that about 96-97% of the energy dissipated in a sequence is associated with the mainshock and the rest is due to aftershocks. Our results for radiated seismic energy and energy-to-moment ratio are partially in agreement with worldwide studies supporting the observation of mechanism dependence of radiated seismic energy. The statistical tests indicate that the only significant difference is for shallow thrust and strike-slip events for these parameters. The statistical comparison of stress drop of shallow thrust versus that of inslab events shows a strongly significant difference with a confidence better than 99%. The comparison of stress drop of shallow thrust events with that of strike-slip events, also indicates a strongly significant difference. We see no dependence of stress drop with magnitude, which is strong evidence of earthquake self-similarity. We do not observe a systematic depth dependence of stress drop. The results also reveal differences in the earthquake rupture among the events. The magnitude difference between the mainshock and the largest aftershock for inslab events is larger than interplate and strike-slip events suggesting focal mechanism dependence of Båth's law. For the case of this parameter, only that for inslab and strike-slip events present a significant difference with 95% confidence.

  15. Adherence to the Dietary Approaches to Stop Hypertension-style diet in relation to glioma: a case-control study.

    Science.gov (United States)

    Benisi-Kohansal, Sanaz; Shayanfar, Mehdi; Mohammad-Shirazi, Minoo; Tabibi, Hadi; Sharifi, Giuve; Saneei, Parvane; Esmaillzadeh, Ahmad

    2016-03-28

    Data on the association of adherence to the Dietary Approaches to Stop Hypertension (DASH)-style and glioma are scarce. We aimed to examine the association between adherence to the DASH-style diet and glioma in Iranian adults. In this study, 128 pathologically confirmed cases of glioma were recruited from hospitals and 256 age- and sex-matched controls were enrolled from other wards of the hospital. Dietary intakes were assessed using a 126-item validated FFQ. Adherence to the DASH-style diet was followed considering the healthy and non-healthy foods emphasised in the DASH dietary pattern. After controlling for potential confounders, individuals with the greatest adherence to the DASH diet were 72 % less likely to have glioma compared with those with the lowest adherence (OR 0·28; 95 % CI 0·13, 0·57). Individuals with the highest consumption of fruits had lower odds for having glioma compared with those with the lowest intake (OR 0·31; 95 % CI 0·14, 0·68). A protective association was also observed between consumption of legumes and nuts and risk of glioma (OR 0·23; 95 % CI 0·10, 0·53). We found a significant positive association between red and processed meat (OR 2·60; 95 % CI 1·16, 5·81) and salt intakes (OR 2·87; 95 % CI 1·30, 6·34) and risk of glioma, after taking all potential confounders into account. Adherence to the DASH-style dietary pattern was inversely associated with glioma. In addition, some components of the DASH diet, including red meats and salt intakes, were positively associated with glioma. Consumption of nuts and legumes as well as fruits was inversely associated with glioma. Prospective cohort studies are required to confirm our findings.

  16. Evidence-based practice and related information literacy skills of nurses in Singapore: an exploratory case study.

    Science.gov (United States)

    Mokhtar, Intan Azura; Majid, Shaheen; Foo, Schubert; Zhang, Xue; Theng, Yin-Leng; Chang, Yun-Ke; Luyt, Brendan

    2012-03-01

    Increased demand for medical or healthcare services has meant that nurses are to take on a more proactive and independent role intending to patients, providing basic treatment and deciding relevant clinical practice. This, in turn, translates into the need for nurses to be able to translate research and evidence into their practice more efficiently and effectively. Hence, competencies in looking for, evaluating, synthesizing and applying documented information or evidence-based practice becomes crucial. This article presents a quantitative study that involved more than 300 nurses from a large government hospital in Singapore. A self-reporting questionnaire was developed to collect data pertaining to evidence-based practice and activities, including those that demonstrate information literacy competencies. Results seem to suggest that the nurses preferred to use print and human information sources compared to electronic information sources; were not proactive in looking up research or evidence-based information and, instead, preferred such information to be fed to them; and that they perceived they lacked the ability to evaluate research papers or effectively search electronic information related to nursing or evidence-based practice. It was also found that more than 80% of the nurses have not had any training related to evidence-based practice.

  17. Mitochondrial haplogroups and control region polymorphisms in age-related macular degeneration: a case-control study.

    Directory of Open Access Journals (Sweden)

    Edith E Mueller

    Full Text Available BACKGROUND: Onset and development of the multifactorial disease age-related macular degeneration (AMD are highly interrelated with mitochondrial functions such as energy production and free radical turnover. Mitochondrial dysfunction and overproduction of reactive oxygen species may contribute to destruction of the retinal pigment epithelium, retinal atrophy and choroidal neovascularization, leading to AMD. Consequently, polymorphisms of the mitochondrial genome (mtDNA are postulated to be susceptibility factors for this disease. Previous studies from Australia and the United States detected associations of mitochondrial haplogroups with AMD. The aim of the present study was to test these associations in Middle European Caucasians. METHODOLOGY/PRINCIPAL FINDINGS: Mitochondrial haplogroups (combinations of mtDNA polymorphisms and mitochondrial CR polymorphisms were analyzed in 200 patients with wet AMD (choroidal neovascularization, CNV, in 66 patients with dry AMD, and in 385 controls from Austria by means of multiplex primer extension analysis and sequencing, respectively. In patients with CNV, haplogroup H was found to be significantly less frequent compared to controls, and haplogroup J showed a trend toward a higher frequency compared to controls. Five CR polymorphisms were found to differ significantly in the two study populations compared to controls, and all, except one (T152C, are linked to those haplogroups. CONCLUSIONS/SIGNIFICANCE: It can be concluded that haplogroup J is a risk factor for AMD, whereas haplogroup H seems to be protective for AMD.

  18. A community-based case-control study of asthma and chronic bronchitis in relation to occupation

    Energy Technology Data Exchange (ETDEWEB)

    Buchanan, D.; Donan, P.T.; Cowie, H.A.; Miller, B.G.; Soutar, C.A.

    1997-07-01

    A community-based epidemiological study was conducted in the West Lothian and Central Regions of Scotland in 1994 by postal questionnaire to investigate the associations between occupations previously held and prevalent symptoms of asthma and chronic bronchitis. 50% of the 34,000 questionnaires were returned. The prevalence of asthma was estimated to be 8% and that of chronic bronchitis was 15%. The prevalence of asthma and of chronic bronchitis related to work was estimated to be 0.5% and 2.2% respectively. Clinical assessments of a sample of respondents confirmed the reliability of diagnoses of asthma using a self-administered questionnaire, but suggested that the work-relatedness of asthma was less reliably diagnosed. Asthma symptoms were particularly implicated with employment in the food processing, catering and textiles industries. Chronic bronchitis symptoms were associated with dusty jobs such as coal mining metal processing and manufacturing of electrical products.

  19. Anxiety disorders and anxiety-related traits and serotonin transporter gene-linked polymorphic region (5-HTTLPR) in adolescents: case-control and trio studies.

    Science.gov (United States)

    Bortoluzzi, Andressa; Blaya, Carolina; Salum, Giovanni A; Cappi, Carolina; Leistner-Segal, Sandra; Manfro, Gisele G

    2014-08-01

    The role of the serotonin transporter gene-linked polymorphic region (5-HTTLPR) in anxiety disorder and anxiety-related traits is controversial. Besides this study, few studies have evaluated the triallelic genotype in adolescents. The aim of this study was to investigate whether anxiety disorders and anxiety-related traits are associated with 5-HTTLPR (biallelic and triallelic) in adolescents, integrating both case-control-based and family-based designs in a community sample. This is a cross-sectional community study of 504 individuals and their families: 225 adolescents (129 adolescents with anxiety disorder and 96 controls) and their biological families. We assessed psychiatric diagnosis using the Kiddie Schedule for Affective Disorders and Schizophrenia. The Temperament and Character Inventory and the Resnick Behavioral Inhibition Scale were used to evaluate harm avoidance and behavioral inhibition. DNA was extracted from saliva and genotyped, including biallelic and triallelic 5-HTTLPR classification, by PCR-RFLP followed by agarose gel electrophoresis. We were not able to find any associations between 5-HTTLPR and anxiety-related phenotypes in both case-control and trio analyses. Further investigation and meta-analytic studies are needed to better clarify the inconsistent results with regard to the association between 5-HTTLPR and anxiety-related phenotypes in adolescents.

  20. The effect of performance-related pay of hospital doctors on hospital behaviour: a case study from Shandong, China

    Directory of Open Access Journals (Sweden)

    Mills Anne

    2005-10-01

    Full Text Available Abstract Background With the recognition that public hospitals are often productively inefficient, reforms have taken place worldwide to increase their administrative autonomy and financial responsibility. Reforms in China have been some of the most radical: the government budget for public hospitals was fixed, and hospitals had to rely on charges to fill their financing gap. Accompanying these changes was the widespread introduction of performance-related pay for hospital doctors – termed the "bonus" system. While the policy objective was to improve productivity and cost recovery, it is likely that the incentive to increase the quantity of care provided would operate regardless of whether the care was medically necessary. Methods The primary concerns of this study were to assess the effects of the bonus system on hospital revenue, cost recovery and productivity, and to explore whether various forms of bonus pay were associated with the provision of unnecessary care. The study drew on longitudinal data on revenue and productivity from six panel hospitals, and a detailed record review of 2303 tracer disease patients (1161 appendicitis patients and 1142 pneumonia patients was used to identify unnecessary care. Results The study found that bonus system change over time contributed significantly to the increase in hospital service revenue and hospital cost recovery. There was an increase in unnecessary care and in the probability of admission when the bonus system switched from one with a weaker incentive to increase services to one with a stronger incentive, suggesting that improvement in the financial health of public hospitals was achieved at least in part through the provision of more unnecessary care and drugs and through admitting more patients. Conclusion There was little evidence that the performance-related pay system as designed by the sample of Chinese public hospitals was socially desirable. Hospitals should be monitored more closely

  1. Importance of relative humidity in the oxidative ageing of organic aerosols: case study of the ozonolysis of maleic acid aerosol

    Directory of Open Access Journals (Sweden)

    P. J. Gallimore

    2011-12-01

    Full Text Available Many important atmospheric aerosol processes depend on the chemical composition of the aerosol, e.g. water uptake and particle cloud interactions. Atmospheric ageing processes, such as oxidation reactions, significantly and continuously change the chemical composition of aerosol particles throughout their lifetime. These ageing processes are often poorly understood. In this study we utilize an aerosol flow tube set up and an ultra-high resolution mass spectrometer to explore the effect of relative humidity (RH in the range of <5–90% on the ozonolysis of maleic acid aerosol which is employed as model organic aerosol system. Due to the slow reaction kinetics relatively high ozone concentrations of 160–200 ppm were used to achieve an appreciable degree of oxidation of maleic acid. The effect of oxidative ageing on the hygroscopicity of maleic acid particles is also investigated using an electrodynamic balance and thermodynamic modelling. RH has a profound effect on the oxidation of maleic acid particles. Very little oxidation is observed at RH < 50% and the only observed reaction products are glyoxylic acid and formic acid. In comparison, when RH > 50% there are about 15 oxidation products identified. This increased oxidation was observed even when the particles were exposed to high humidities long after a low RH ozonolysis reaction. This result might have negative implications for the use of water as an extraction solvent for the analysis of oxidized organic aerosols. These humidity-dependent differences in the composition of the ozonolyzed aerosol demonstrate that water is both a key reactant in the oxidation scheme and a determinant of particle phase and hence diffusivity. The measured chemical composition of the processed aerosol is used to model the hygroscopic growth, which compares favourably with water uptake results from the electrodynamic balance measurements. A reaction mechanism is presented which takes into account the RH dependent

  2. CASE STORAGE BASED ON RELATIONAL DATABASE

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    This paper focused on the integration of case base and relational database management system (RDBMS). The organizational and commercial impact will be far greater if the case-based reasoning (CBR) system is integrated with main stream information system, which is exemplified by RDBMS. The scalability, security and robustness provided by a commercial RDBMS facilitate the CBR system to manage the case base.The virtual table in relational database (RDB) is important for CBR systems to implement the flexibility of case template. It was discussed how to implement a flexible and succinct case template, and a mapping model between case template and RDB was proposed. The key idea is to build the case as the virtual view of underlying data.

  3. Ethical issues related to managed care: an in-depth discussion of an occupational therapy case study.

    Science.gov (United States)

    Lohman, H; Brown, K

    1997-01-01

    What are the ethical responsibilities of occupational therapists when managed care plans override their clinical judgment and deny reimbursement for needed assessment or therapy? Using an example from a true case, this article presents an analysis of the ethical problems experienced in managed care when explicit business goals are in conflict with the humanistic commitments of our field. Strategies for ethical action are recommended, including: good communication with the case manager, effective advocacy for the patient, consultation with ethics resources, and advocacy at the policy-making level. [Article copies available for a fee from The Haworth Document Delivery Service: 1-800-342-9678. E-mail address: getinfo@haworth.com].

  4. Teacher- or Learner-Centred? Science Teacher Beliefs Related to Topic Specific Pedagogical Content Knowledge: A South African Case Study

    Science.gov (United States)

    Mavhunga, Elizabeth; Rollnick, Marissa

    2016-12-01

    In science education, learner-centred classroom practices are widely accepted as desirable and are associated with responsive and reformed kinds of teacher beliefs. They are further associated with high-quality Pedagogical Content Knowledge (PCK). Topic-Specific Pedagogical Content Knowledge (TSPCK), a version of PCK defined at topic level, is known to enable the transformation of topic content into a form accessible to learners. However, little is known about teacher science beliefs in relation to TSPCK and therefore the nature of likely associated classroom practices. In this study, we investigated the relationship between TSPCK and underlying science teacher beliefs following an intervention targeting the improvement of TSPCK in the topic chemical equilibrium. Sixteen final year pre-service chemistry teachers were exposed to an intervention that explicitly focussed on knowledge for transforming the content of chemical equilibrium using the five knowledge components of TSPCK. A specially designed TSPCK instrument in chemical equilibrium and the Teacher Belief Instrument (TBI) were used to capture written responses in pre- and post-tests. Additional qualitative data was collected from audio-recorded discussions and written responses from an open-ended question asked before and after the intervention. Two key findings emerged from the study. Firstly, the development of TSPCK was linked to shifts in underlying science teacher beliefs in the direction of learner-centred teaching for the majority of pre-service teachers. Secondly, this shift was not evident for all, as for some there was development of TSPCK without a shift from teacher-centred beliefs about science teaching.

  5. Hypervigilance or avoidance of trigger related cues in migraineurs? - A case-control study using the emotional stroop task

    Directory of Open Access Journals (Sweden)

    Puschmann Anne-Katrin

    2011-11-01

    Full Text Available Abstract Background "Negative affect" is one of the major migraine triggers. The aim of the study was to assess attentional biases for negative affective stimuli that might be related to migraine triggers in migraine patients with either few or frequent migraine and healthy controls. Methods Thirty-three subjects with frequent migraine (FM or with less frequent episodic migraine, and 20 healthy controls conducted two emotional Stroop tasks in the interictal period. In task 1, general affective words and in task 2, pictures of affective faces (angry, neutral, happy were used. For each task we calculated two emotional Stroop indices. Groups were compared using one-way ANOVAs. Results The expected attentional bias in migraine patients was not found. However, in task 2 the controls showed a significant attentional bias to negative faces, whereas the FM group showed indices near zero. Thus, the FM group responded faster to negative than to positive stimuli. The difference between the groups was statistically significant. Conclusions The findings in the FM group may reflect a learned avoidance mechanism away from affective migraine triggers.

  6. Spatial prevalence of intellectual disability and related socio-demographic factors in Iran, using GWR: Case study (2006

    Directory of Open Access Journals (Sweden)

    Ali Goli

    2014-01-01

    Full Text Available Background: Although intellectual disability (ID is a common disability in Iran, there is no investigation on the spatial distribution pattern of these patients in national level and the spatial maps for recognition the areas with higher prevalence of IDs and local neighborhoods of these regions or effect of socio-demographic factor on this scattering is not still available. This proposition motivated us to assess the population with ID in our country. Methods: In a cross-sectional study, we applied Moran′s Index (Moran′s I which includes information about the strength of the neighboring association between counties, as global univariate distribution assessment. A geographically weighted regression was used to explore relation between ID patient′s prevalence and some socio-demographic factors (migration and illiteracy rate, physician number (PN/10,000 people and health-care centers (HCCs/10,000 people. Results: We found that spatial clusters of ID patients exist among Iran counties (Moran′s I = 0.36, P 0.3. Conclusions: According to the results, our Initial hypothesis about the existence of spatial clusters in distribution of people with ID in Iran was proven. Spatial autocorrelation between migration and illiteracy rate and prevalence of patients with ID was shown and was in agreement with our hypothesis. However, our supposition that the prevalence should have inverse relationship with PN and HCC was rejected.

  7. [Violence-related deaths in Argentina: two case studies in the cities of Venado Tuerto and San Rafael].

    Science.gov (United States)

    Spinelli, Hugo; Alazraqui, Marcio; Galeano, Diego; Calandrón, Sabrina

    2012-12-01

    This article presents the results of a comparative study of two Argentinian cities, namely Venado Tuerto and San Rafael, which revealed different trends in the rates of firearm-related homicides. The methodology combined two strategies of analysis: semi-structured interviews with key informants (municipal and provincial government agents in different areas of management, as well as members of non-governmental organizations) and focus groups with actors involved in medical care, education, and religious institutions. The results suggest little difference between cities in which rates have increased and those in which rates have decreased. The most significant difference was that in Venado Tuerto a greater fragility of public institutions was observed due to the lack of articulation between such institutions. In San Rafael, the actors interviewed attribute the low level of conflict to a violence prevention network in which provincial and municipal agencies interact. Although neither city is violent at the most critical Latin American levels, the different results shown in Venado Tuerco and San Rafael indicate the possibility of bringing institutions together in a joint framework of conversations, agreements and policies.

  8. Objectivist case study research

    DEFF Research Database (Denmark)

    Ridder, Hanne Mette Ochsner; Fachner, Jörg

    2016-01-01

    be achieved through the use of objectivist case study research. The strength of the case study design is that it allows for uncovering or suggesting causal relationships in real-life settings through an intensive and rich collection of data. According to Hilliard (1993), the opposite applies for extensive...... designs, in which a small amount of data is gathered on a large number of subjects. With the richness of data, the intensive design is ―the primary pragmatic reason for engaging in single-case or small N research‖ (p. 374) and for working from an idiographic rather than a nomothetic perspective....

  9. The Epidemiology of Infectious Gastroenteritis Related Reactive Arthritis in U.S. Military Personnel: A Case-Control Study

    Science.gov (United States)

    2010-09-13

    enterotoxigenic E. coli (ETEC)[10,24], Cryptosporidium spp[25,26], Giardia lamblia[27], Strongyloides stercoralis[28], and possibly Schistosoma...Specifically, approximately 13% of the 12 N.A.A cases were seen for physical therapy , 4% for lumbago, and 3% for aftercare following surgery. None of

  10. A priori fully populated covariance matrices in least-squares adjustment—case study: GPS relative positioning

    Science.gov (United States)

    Kermarrec, Gaël; Schön, Steffen

    2016-12-01

    In this contribution, using the example of the Mátern covariance matrices, we study systematically the effect of apriori fully populated variance covariance matrices (VCM) in the Gauss-Markov model, by varying both the smoothness and the correlation length of the covariance function. Based on simulations where we consider a GPS relative positioning scenario with double differences, the true VCM is exactly known. Thus, an accurate study of parameters deviations with respect to the correlation structure is possible. By means of the mean-square error difference of the estimates obtained with the correct and the assumed VCM, the loss of efficiency when the correlation structure is missspecified is considered. The bias of the variance of unit weight is moreover analysed. By acting independently on the correlation length, the smoothness, the batch length, the noise level, or the design matrix, simulations allow to draw conclusions on the influence of these different factors on the least-squares results. Thanks to an adapted version of the Kermarrec-Schön model, fully populated VCM for GPS phase observations are computed where different correlation factors are resumed in a global covariance model with an elevation dependent weighting. Based on the data of the EPN network, two studies for different baseline lengths validate the conclusions of the simulations on the influence of the Mátern covariance parameters. A precise insight into the impact of apriori correlation structures when the VCM is entirely unknown highlights that both the correlation length and the smoothness defined in the Mátern model are important to get a lower loss of efficiency as well as a better estimation of the variance of unit weight. Consecutively, correlations, if present, should not be neglected for accurate test statistics. Therefore, a proposal is made to determine a mean value of the correlation structure based on a rough estimation of the Mátern parameters via maximum likelihood

  11. A cohort study of recurrence patterns among more than 54,000 relatives of oral cleft cases in Denmark

    DEFF Research Database (Denmark)

    Grosen, Dorthe; Chevrier, Cécile; Skytthe, Axel;

    2010-01-01

    does have an effect on recurrence in first degree relatives and the type of cleft is predictive of the recurrence type. Highly reliable estimates of recurrence have been provided for first cousins in addition to more accurate estimates for first and second degree relatives. These results...

  12. Factors affecting rate of stroke-related death in elderly male military population A 23-year cohort study of 1 268 cases in Xi'an, China

    Institute of Scientific and Technical Information of China (English)

    Yanhua Li; Yu Sun; Xiaoyong Sai; Yao He; Qiang Wu; Yongping Yan; Ke Men; Liangshou Li

    2011-01-01

    The study is the first long-term cohort study examining stroke and its subtypes among a population of Chinese elderly male retired military veterans. We reported on a 23-year cohort study examining stroke in 1 268 elderly male patients living in Xi'an, China since 1987. The stroke-related mortality rate in this cohort was 361.50/1 × 106 per year. Cerebral hemorrhage was the dominant cause of death, with 28 cases of fatal cerebral infarction and 49 cases of fatal cerebral hemorrhage among 77 stroke-related deaths. Independent risk factors for stroke mortality included age, blood pressure, smoking, body mass index, family history of hypertension, past medical history of stroke, hypertension and hyperlipidemia. Among them, ischemic stroke mortality correlated with age, smoking, family history of hypertension and past medical history of stroke, while hemorrhagic stroke was related to blood pressure, body mass index and past medical history of hypertension. Our results indicated that maintaining appropriate levels of blood pressure and body mass, smoking cessation and prevention of hyperlipidemia can reduce the risk of stroke-related death in elderly males who are retired from military service.

  13. Soil fertility in relation to slope position and agricultural land use: a case study of Umbulo Catchment in southern Ethiopia.

    Science.gov (United States)

    Moges, Awdenegest; Holden, Nicholas M

    2008-11-01

    A study was conducted in southern Ethiopia to evaluate the nutrient status on smallholder farms with respect to land use class (garden, grassland, and outfield) and slope position (upper, middle, and lower). Soil physical and chemical properties were quantified using soil samples collected at two depths (0-15 and 15-30 cm). Available phosphorous was significantly different among the three land use classes. However, organic carbon and total nitrogen were lower in the outfield compared to the garden and grass land but not significantly different. The lower than expected nutrient status of the garden and grassland, which receive almost all available organic supplements, was attributed to the overall low availability of these inputs. Similarly, pH and cation exchange capacity were not significantly different among the different land use classes. However, the sum of the exchangeable cations was significantly higher in the garden compared to the outfields. Comparison at landscape level revealed that the sand fraction was significantly greater, whereas the silt fractions were significantly smaller, on the lower slopes relative to the middle slopes. Moreover, the organic carbon, total nitrogen, cation exchange capacity, Ca, and Mg values were significantly less on lower slopes than upper and middle slopes. Perhaps this is because of leaching and the effect of deposition of coarser sediments from the prevailing gully system. Overall, the fertility of the soil was adequate for supporting smallholder farming, but consideration must be given to reducing pressure on the land resources, addressing erosion problems, and providing a line of credit for purchasing inputs.

  14. Applying DNA Barcodes to Identify Closely Related Species of Ferns: A Case Study of the Chinese Adiantum (Pteridaceae).

    Science.gov (United States)

    Wang, Fan-Hong; Lu, Jin-Mei; Wen, Jun; Ebihara, Atsushi; Li, De-Zhu

    2016-01-01

    DNA barcoding is a fast-developing technique to identify species by using short and standard DNA sequences. Universal selection of DNA barcodes in ferns remains unresolved. In this study, five plastid regions (rbcL, matK, trnH-psbA, trnL-F and rps4-trnS) and eight nuclear regions (ITS, pgiC, gapC, LEAFY, ITS2, IBR3_2, DET1, and SQD1_1) were screened and evaluated in the fern genus Adiantum from China and neighboring areas. Due to low primer universality (matK) and/or the existence of multiple copies (ITS), the commonly used barcodes matK and ITS were not appropriate for Adiantum. The PCR amplification rate was extremely low in all nuclear genes except for IBR3_2. rbcL had the highest PCR amplification rate (94.33%) and sequencing success rate (90.78%), while trnH-psbA had the highest species identification rate (75%). With the consideration of discriminatory power, cost-efficiency and effort, the two-barcode combination of rbcL+ trnH-psbA seems to be the best choice for barcoding Adiantum, and perhaps basal polypod ferns in general. The nuclear IBR3_2 showed 100% PCR amplification success rate in Adiantum, however, it seemed that only diploid species could acquire clean sequences without cloning. With cloning, IBR3_2 can successfully distinguish cryptic species and hybrid species from their related species. Because hybridization and allopolyploidy are common in ferns, we argue for including a selected group of nuclear loci as barcodes, especially via the next-generation sequencing, as it is much more efficient to obtain single-copy nuclear loci without the cloning procedure.

  15. Detecting land-cover change using mappable vegetation related indices: A case study from Sinharaja Man and the Biosphere Reserve

    Directory of Open Access Journals (Sweden)

    BD Madurapperuma

    2014-06-01

    Full Text Available This study evaluates multi-year changes of vegetation in the Sinharaja Man and the Biosphere (MAB reserve using mappable vegetation related indices viz., Normalized Difference Vegetation Index (NDVI and Burn Index (BI. Land-cover changes in the Sinharaja MAB reserve were detected using Landsat 7 ETM+ images for 1993, 2001, and 2005. Seven individual bands of each image were converted to new multiband files by layer stacking using ENVI® 4.5. Then the multiband files were re-projected to UTM Zone 44 North, WGS-84 Datum. Each data set was exported to ENVI® EX software package to detect the changes between time steps based on NDVI and BI using an image difference tool. Land-cover data, which were obtained from the DIVA GIS web portal, were compared with Landsat image data. Results of BI showed that the Sinharaja MAB reserve fringe was vulnerable to forest fire. For example, from 1993- 2001, 160 ha identified as burned area. In contrast, from 2001-2005, 79 ha burned, and for the entire period of 1993-2005, 10 ha burned. NDVI resulted in a 962 ha increase of vegetation prime at the western Sinharaja from 2001-2005. In addition, there was a 15 ha decrease in vegetation from 1993-2005. The results were visualized using an embedded 3D render window of Google Earth and 2D view of ArcGIS explorer online. In conclusion, in-situ ground truthing data is needed for the fire-influenced area for implementing sustainable forest resource management at the Sinharaja MAB reserve. Normal 0 false false false EN-GB X-NONE X-NONE

  16. Examining Participation in Relation to Students' Development of Health-Related Action Competence in a School Food Setting: LOMA Case Study

    Science.gov (United States)

    Ruge, Dorte; Nielsen, Morten Kromann; Mikkelsen, Bent Egberg; Bruun-Jensen, Bjarne

    2016-01-01

    Purpose: The purpose of this paper is to examine how students' participation in an integrated school food program was related to the development of components of food and health-related action competence (F & HRAC). These components were understood to be the knowledge, insight, motivation, ownership and social skills that made students able to…

  17. Approach to the research and the situation of Public Relations in Europe. Comparative study between German and Spanish cases

    Directory of Open Access Journals (Sweden)

    Dra. María Isabel Míguez González

    2007-01-01

    Full Text Available With the aim of bring near to the spanish academic field the european approaches of Public Relations, this article makes a compared revision of the situation of this subject and profession in Germany and Spain. This revision shows important resemblances on the use of the term “public relations”, the confusion of this subject with other communicative activities, the professional development and the problems of the field in both countries. However, it also shows that Germany has more tradition on public relations research than Spain and, therefore, it has a more extensive corpus of theories about this subject. For this reason, since important resemblances exist in other aspects, german research on public relations could be interesting for the spanish academic field both to explain the situation of public relations in Spain and to motivate theoretical development in our country.

  18. The effect of financing hospital health care providers through updated Diagnosis Related Groups. Case studies: the municipal hospitals in Romania

    OpenAIRE

    Emil OLTEANU; Attila TAMAS SZORA; Iulian Bogdan DOBRA

    2014-01-01

    In our scientific approach we tried to develop a model with which to highlight the effect of financing hospital health care providers using the hospital 's Diagnosis Related Groups (DRG) and Mean Relative Values (MRV). The econometric model used is simple linear regression model form. Development of the model was performed by using the EViews 7 to the municipal hospitals in Romania during 2010 - 2012, being considered DRG dependent variable and independent variabl...

  19. A BSC-DEA approach to measure the relative efficiency of service industry: A case study of banking sector

    Directory of Open Access Journals (Sweden)

    M. B. Aryanezhad

    2011-04-01

    Full Text Available Performance evaluation plays an important role in determining faults and difficulties of any organization as well as attempting to increase capabilities and improve activities. Data envelopment analysis (DEA, as a non-parametric method, has been one of the most important and significant management tools for measuring output or efficiency. In this paper, we propose a method to utilize balanced score card (BSC as a tool for designing performance evaluation indices of an organization. The integrated BSC-DEA has been applied as an empirical case for a major private bank organization and the results are analyzed.

  20. Review of Studies Related to Pedagogical Content Knowledge in the Context of Science Teacher Education: Turkish Case

    Science.gov (United States)

    Aydin, Sevgi; Boz, Yezdan

    2012-01-01

    As a review study, the present study was carried out in order to introduce PCK construct to researchers and evaluate which aspects of PCK were studied in our country, and, finally, make recommendations in light of the analysis of the studies for further research. For this purpose, ERIC database, YOK (Higher Education Council) database were…

  1. Characterisation of gastric cancer and its relation to environmental factors: a case study in Shenqiu County, China.

    Science.gov (United States)

    Ren, Hongyan; Xu, Duanyang; Shi, Xiaoming; Xu, Jianwei; Zhuang, Dafang; Yang, Gonghuan

    2016-01-01

    This article presents the results of spatial analysis of gastric cancer and its relation to environmental conditions in Shenqiu County, China. Retrospective data on gastric cancer mortality (GCM) were analysed at various spatial scales, with its relation to environmental factors explored at an appropriate scale. The results considered 2 × 2 km(2) grid as the optimal level for characterising GCM due to the highest Moran's I (I = 0.68, p environmental conditions. We suggest that preventive measures for controlling the environment-related malignant neoplasm should not be limited in the regions suffering from this disease but be reasonably extended to surrounding areas.

  2. The effect of financing hospital health care providers through updated Diagnosis Related Groups. Case studies: the municipal hospitals in Romania

    Directory of Open Access Journals (Sweden)

    Emil OLTEANU

    2014-11-01

    Full Text Available In our scientific approach we tried to develop a model with which to highlight the effect of financing hospital health care providers using the hospital 's Diagnosis Related Groups (DRG and Mean Relative Values (MRV. The econometric model used is simple linear regression model form. Development of the model was performed by using the EViews 7 to the municipal hospitals in Romania during 2010 - 2012, being considered DRG dependent variable and independent variables: C and MRV. Analyzing in detail the results recorded by providers following simple regression model is observed that there are units which, although recorded low values in the number of patients discharged, they were able to achieve a relatively high VRM or to contract a level of TAC over average of the entire sample.

  3. School-based peer-related social competence interventions for children with autism spectrum disorder: a meta-analysis and descriptive review of single case research design studies.

    Science.gov (United States)

    Whalon, Kelly J; Conroy, Maureen A; Martinez, Jose R; Werch, Brittany L

    2015-06-01

    The purpose of this review was to critically examine and summarize the impact of school-based interventions designed to facilitate the peer-related social competence of children with autism spectrum disorder (ASD). Reviewed studies employed a single-case experimental design, targeted peer-related social competence, included children 3-12 years old with an ASD, and took place in school settings. Articles were analyzed descriptively and using the evaluative method to determine study quality. Additionally, effect size estimates were calculated using nonoverlap of all pairs method and Tau-U. A total of 37 studies including 105 children were reviewed. Overall, ES estimates ranged from weak to strong, but on average, the reviewed interventions produced a moderate to strong effect, and quality ratings were generally in the acceptable to high range. Findings suggest that children with ASD can benefit from social skill interventions implemented with peers in school settings.

  4. Causal Judgments of Positive Mood in Relation to Self-Regulation: A Case Study with Flemish Students

    Science.gov (United States)

    Human-Vogel, Salome; van Petegem, Peter

    2008-01-01

    To examine students' causal judgements of positive mood in relation to self-regulation, 128 participants from two different schools representing two distinct educational environments (Technical/Vocational School (TSO/BSO): N = 63; General Secondary School (ASO): N = 65) were asked to judge 45 statements containing three possible relationships (A…

  5. Association between Low-density Lipoprotein Receptor-related Protein 5 Polymorphisms and Type 2 Diabetes Mellitus in Han Chinese:a Case-control Study

    Institute of Scientific and Technical Information of China (English)

    YOU Hai Fei; WANG Yan; WANG Qian; WANG Bing Yuan; REN Yong Cheng; HU Dong Sheng; ZHAO Jing Zhi; ZHAI Yu Jia; YIN Lei; PANG Chao; LUO Xin Ping; ZHANG Ming; WANG Jin Jin; LI Lin Lin

    2015-01-01

    Objective To investigate the association between low-density lipoprotein receptor-related protein 5 (LRP5) variants (rs12363572 and rs4930588) and type 2 diabetes mellitus (T2DM) in Han Chinese. Methods A total of 1842 T2DM cases (507 newly diagnosed cases and 1335 previously diagnosed cases) and 7777 controls were included in this case-control study. PCR-RFLP was conducted to detect the genotype of the two single nucleotide polymorphisms (SNPs). Odds ratios (ORs) and 95%confidence intervals (95%CIs) were calculated to describe the strength of the association by logistic regression. Results In the study subjects, neither rs12363572 nor rs4930588 was significantly associated with T2DM, even after adjusting for relevant covariates. When stratified by body mass index (BMI), the two SNPs were also not associated with T2DM. Among the 3 common haplotypes, only haplotype TT was associated with reduced risk of T2DM (OR 0.820, 95% CI 0.732-0.919). In addition, rs12363572 was associated with BMI (P Conclusion No LRP5 variant was found to be associated with T2DM in Han Chinese, but haplotype TT was found to be associated with T2DM.

  6. Nucleoplasty as a therapeutic option for lumbar disc degeneration related pain: a retrospective study of 396 cases

    Directory of Open Access Journals (Sweden)

    José Lourenço Kallás

    2013-01-01

    Full Text Available OBJECTIVES: To make a retrospective analysis and evaluate a clinical response to the control of disc degeneration related pain of 396 patients submitted to percutaneous lumbar nucleoplasty; and to make a record of visual analogical scale (VAS up to a three-year follow-up after the surgical procedure. METHODS: Analysis of VAS score in 396 patients with lumbar disc degeneration related pain, according to anamnesis, clinical examination and magnetic resonance imaging (MRI, without improvement of previous clinical treatment, submitted to percutaneous nucleoplasty. RESULTS: A total of 26% of the patients presented 100% remission of pain or paresthesia, of whom 75% showed at least 50% of pain improvement. The median VAS pain improvement was about 67%. CONCLUSIONS: The median VAS improvement in inferior disc levels was higher than four points. The VAS showed improvement of the pain and paresthesia up to a three-year follow up after the surgical procedure.

  7. University and industry relations : a case study analysis of two marine science research institutes in the Philippines

    OpenAIRE

    Batac, Catherine

    2007-01-01

    University-industry linkages in the Philippines have received more attention in the last few years. Centers of Excellence (CoEs) and Centers of Development (CoDs) have emerged. These are the selection of public and private institutions which have demonstrated the highest degree or level of standards along the areas of instruction, research and extension. The ministry of education in the country had in fact begun to encourage such relations by including in its CoEs criteria the capability of ...

  8. DNA barcoding in closely related species: A case study of Primula L.sect.Proliferae Pax (Primulaceae) in China

    Institute of Scientific and Technical Information of China (English)

    Hai-Fei YAN; Gang HAO; Chi-Ming HU; Xue-Jun GE

    2011-01-01

    DNA barcoding is a method of identifying species by analyzing one or a few short standardized DNA sequences. There are particular challenges in barcoding plants, especially for distinguishing closely related species. Hence, there is an urgent need to evaluate the performance of candidate loci for distinguishing between species, especially closely related species, to complement the rbcL + matK combination suggested as the core barcode for land plants. We sampled 48 individuals representing 12 species in Primula sect. Proliferae Pax in China to evaluate the performance of eight leading candidate barcode loci (matK, rbcL, rpoB, rpoCl, trnH-psbA, psbK-psbI, atpFatpH, and internal transcribed spacer (ITS)). The core combination rbcL + matK gave only 50% species resolution in sect. Proliferae. In terms of intraspecies and interspecies divergence, degree of monophyly, and sequence similarity, ITS, trnH-psbA, and psbK-psbI showed good performance as single-locus barcodes. Internal transcribed spacer displayed the highest genetic divergence and best discriminatory power, both alone and in combination with rbcL +matK (83.3% species resolution). We recommend evaluating the use of ITS for barcoding in other species. Low or single copy nuclear regions would provide more sophisticated barcoding tools in the long term, even though further research is required to find suitable loci.

  9. Research on Model of Guiding Rural Residents’ Relatively Centralized Residence——A Case Study of Chongqing City

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    On the basis of expounding the status quo of rural residents’ residence, the thesis notes that influenced by the weak foundation of rural economy, the characteristic of mountain landscape, smallholder consciousness, shortage of capital and other factors, the rural residents in Chongqing City mainly live scattered. In addition to opportunities of the expansion and drive of city, rural market development, rural resources development, rural industrial development, and rural ecological migration, the model of urban development promotion, the model of market development drive, the model of land development drive, the model of rural industry construction and the model of resettlement and reconstruction are advocated in order to guide the rural residents to adopt relative centralized residence. The suggestions concerning guiding rural residents’ relative centralized residence are put forward as follows: firstly, act according to circumstances and conduct scientific planning and design; secondly, propagate extensively and activate famers’ willingness; thirdly, first experiment and exert the exemplary guide; fourthly, perfect policy and guarantee farmers’ benefit; fifthly, strengthen leadership and decrease the risk of centralized residence; sixthly, boost gradually and realize moderate centralized residence.

  10. Sampling strategy and potential utility of indels for DNA barcoding of closely related plant species: a case study in taxus.

    Science.gov (United States)

    Liu, Jie; Provan, Jim; Gao, Lian-Ming; Li, De-Zhu

    2012-01-01

    Although DNA barcoding has become a useful tool for species identification and biodiversity surveys in plant sciences, there remains little consensus concerning appropriate sampling strategies and the treatment of indels. To address these two issues, we sampled 39 populations for nine Taxus species across their entire ranges, with two to three individuals per population randomly sampled. We sequenced one core DNA barcode (matK) and three supplementary regions (trnH-psbA, trnL-trnF and ITS) for all samples to test the effects of sampling design and the utility of indels. Our results suggested that increasing sampling within-population did not change the clustering of individuals, and that meant within-population P-distances were zero for most populations in all regions. Based on the markers tested here, comparison of methods either including or excluding indels indicated that discrimination and nodal support of monophyletic groups were significantly increased when indels were included. Thus we concluded that one individual per population was adequate to represent the within-population variation in these species for DNA barcoding, and that intra-specific sampling was best focused on representing the entire ranges of certain taxa. We also found that indels occurring in the chloroplast trnL-trnF and trnH-psbA regions were informative to differentiate among for closely related taxa barcoding, and we proposed that indel-coding methods should be considered for use in future for closed related plant species DNA barcoding projects on or below generic level.

  11. Water pollution in relation to mineral exploration: a case study from Alayi-Ovim area of southeastern Nigeria.

    Science.gov (United States)

    Ibe, Kalu K; Akaolisa, Casmir C Zanders

    2012-05-01

    Water samples from rivers, streams, springs, and shallow wells in Alayi-Ovim area of southeast Nigeria have been analyzed for Pb, Ca, Mg, Fe, Mg, PO(4), NO(3), CO(3), SO(4), Cl, and pH. The analyses were carried out using atomic absorption spectrometer and Hach Direct Reading Equipment. Results of the analyses from the area conform to the WHO (1995) standards for drinking water. However, the results show relative enrichment of Ca, pH, Mg, CO(3), and Cl. Low values were obtained for Fe, SO(4), and NO(3). While the Cl and Pb enrichment in the area north of Alayi-Ovim axis is attributed to proximity to the lead-zinc and chloride-rich formations of the Turonian Eze-Aku and the Albian Asu River; the Ca, Mg, SO(4), and CO(3) enrichment in Southern part of Alayi-Ovim is due to the limestone-bearing Late Maastrichtian Nsukka Formation. Furthermore, the very low values of less than 5 ppm for these characters in water in the central region correlate well with the relatively clean Maastrichtian quartz arenite Ajali Sandstone Formation. The Pb-Zn and Cl incursions into the water system from the Older Albian Asu River/Turonian Eze-Aku Formations in the northern part of Alayi-Ovim area and the leaching of Mg, and Ca into the water system in the Maastrichtian limestone area in the south thus constitute geochemical indices for chemical pollution and mineral exploration for brine and dolomitic limestone in the area.

  12. Strike-slip tectonics, related basin formation, and sedimentology in zones of continental escape: Turkey as a case study

    Energy Technology Data Exchange (ETDEWEB)

    Sengor, A.M.C.; Gorur, N.

    1984-04-01

    Since the Tortonian (11 Ma), the tectonics of Turkey has been dominated by its escape westward from the east Anatolian collision zone onto the oceanic lithosphere of the eastern Mediterranean, mainly along the north and east Anatolian transform faults (NAT and EAT), and at least two other southeast-concave strike-slip faults that branch off the NAT near Erzincan and Resadiye. The Aegean graben system is a broad shear zone between the latter of these and the Grecian shear zone. At triple junctions involving the NAT/EAT and EAT/Dead Sea transform fault, space problems arise, giving rise to the Karliova and Adana/Cilicia basins, respectively. In Thrace, where the NAT takes a southwesterly bend, part of the resulting constraint is released by rifting in a northwest orientation that formed the Ergene basin. In addition, various pull-apart structures and leaky strike-slip faults contribute to the richness of strike-slip-related negative structures in Turkey. Some of these are of lithospheric dimensions and contain thousands of meters of sediment, whereas others formed within thinner crustal flakes above decollement horizons. Because escape tectonics necessarily involves subduction, arc-related strike-slip deformation may interfere with that indigenous to collision tectonics, as in south Turkey. Continental convergence eventually eliminates all subductable areas along the collision front and the structures generated by escape regimes may fall prey to compressional obliteration. In zones of complex and multiple continental collision such as Turkey, several episodes of escape tectonics may alternate with intracontinental compressional deformation, whereby the products of the older escape regimes would be very difficult to recognize. The present tectonics of Turkey constitutes an excellent guide to earlier episodes of escape tectonics in and around Turkey.

  13. Research on Social Issues and Related Planning Theory of Major Resettlement Project: A Case Study on Three Gorges Area

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Secondary disasters and crises such as disordered development and environmental pollution occurring amid the human resettlement process have been a heated academic focus in the field of urban and rural planning. However, the social issues involved in this process have not been given enough attention. This paper studies secondary man-caused disasters with respect to the natural environment and the social and cultural systems, which are linked together by the rapid urbanization process, in order to provide references for future theoretical and practical urban and rural planning studies. The study reveals that during resettlement, typical social issues such as societal anomie, social stratification, and individual poverty have occurred in the Three Gorges Area. The primary cause is that stimulated by rapid urbanization, human settlement development and social evolution have formed a double helix model composed of time and space that is similar to a DNA model, and any mismatched occurrences on either side will likely lead to a social structural problem. As an academic response to the significant urbanization process that is taking place in China, this study reflects the political and economic trends in global environmental change research, as well as the technology trends in humanity studies.

  14. A study of the relation between the spatial structure of the city and the quality of urban development using Space Syntax A case study of Mashhad

    Directory of Open Access Journals (Sweden)

    M. Abbaszadegan

    2012-01-01

    components, because numerous studies have shown that there is a strong correlation between changes in integration value and pedestrian movement in the city.3– DiscussionAccording to the main question and the basic theory of this research, the development quality of 136 neighborhoods in Mashhad has been analysed based on 20 indicators such as economical, social, and physical and welfare groups. The method used for analyzing data and determining the quality of development, is the integration of factor analysis with numerical taxonomy analysis. Space syntax is the analyzing method of Mashhad neighborhoods’ spatial structure. Accordingly, the axial map of Mashhad was prepared and it was analyzed by space syntax theory. In this study, the integration value was investigated at three radiuses including Rn, R3, and R-R for 136 neighborhoods in Mashhad. By finding the results for quality of development and integration value in each neighborhood, the hypothesis of this research has been examined using the statistical methods such as correlation.4– ConclusionThere is indeed, a direct meaningful relation between the integration value resulted from space syntax analysis and their quality of developement in all mentioned radius in Mashhad neighborhoods. So, neighborhoods with high Radius- radius integration value which also have a significant relation with city spatial structure are more developed and in other words, their development is more sustainable.Among the development criteria, the social and economic factors had a more meaningful relation with integration values than welfare and environmental factors. Thus, with changes in household economical condition (e.g. increasing household income per capita and social condition (e.g. job promotion and increscent of household education level, people mostly tend to move and reside in neighborhoods with high integration value, so this displacement leads to physical and welfare development increase in those neighborhoods.5– Suggestions

  15. Case Studies in Biology.

    Science.gov (United States)

    Zeakes, Samuel J.

    1989-01-01

    A case study writing exercise used in a course on parasitology was found to be a powerful learning experience for students because it involved discipline-based technical writing and terminology, brought the students in as evaluators, applied current learning, caused interaction among all students, and simulated real professional activities. (MSE)

  16. An investigation of relation between organizational justice and professional commitment of staff: A case study of public organization in Kermanshah

    Directory of Open Access Journals (Sweden)

    Mostafa Emami

    2013-05-01

    Full Text Available This paper presents an empirical study to investigate the relationship between organizational justice and professional commitment in Kermanshah official organizations. The study uses 20 questions to measure professional commitment from a questionnaire originally developed by Spell et al. (2007 [Spell, C. S., & Arnold, T. J. (2007. A multi-level analysis of organizational justice climate, structure, and employee mental health. Journal of Management, 33(5, 724-751.]. In addition, the study adopts 12 questions from another questionnaire developed by Vallas (1999 [Vallas, S. P. (1999. Rethinking post‐Fordism: The meaning of workplace flexibility. Sociological theory, 17(1, 68-101.] to measure organizational justice. Cronbach alpha for organizational justice questionnaire and professional commitment are 0.81 and 0.89, respectively, which are well above the minimum acceptable level. Based on the results of this survey, there is a positive and meaningful relationship between organizational justice and professional commitment. The implementation of the linear regression analysis also reveals that there is a positive and meaningful relationship between inter-organizational justice and professional commitment. The study performs Freedman test to rank three components of organizational justice and the results indicate that interactional justice maintains the highest level of importance while distributive justice comes last in terms of priority.

  17. Teacher-Parent Relations and Professional Strategies: A Case Study on Documentation and Talk about Documentation in a Swedish Preschool

    Science.gov (United States)

    Löfdahl, Annica

    2014-01-01

    The article is framed by a project designed to study the teacher profession in a current Swedish preschool through work on systematic documentation of quality. Questions deal with how teachers handle the demands on visibility, how they perform and what aspects of the teaching profession will be exposed and what parts will be silenced. This article…

  18. Heavy carbon travertine related to methane generation: A case study of the Big Tarkhan cold spring, Kerch Peninsula, Crimea

    Science.gov (United States)

    Kokh, Svetlana N.; Shnyukov, Yevgeny F.; Sokol, Ella V.; Novikova, Sofya A.; Kozmenko, Olga A.; Semenova, Dina V.; Rybak, Elena N.

    2015-07-01

    The Big Tarkhan cold spring is located within the Bulganak zone of mud volcanism in the northern Kerch Peninsula (Crimea). The spring waters mainly have Cl-HCO3-Na-Ca chemistry and temperatures from 18 to 23 °C. Active travertine deposition at the site produces abundant calcite and minor amounts of siderite, halite, tincalconite, trona, gaylussite, northupite and amorphous iron hydroxides. Calcite contains the impurities of 0.26-2.16 wt.% MgO, up to 0.87 wt.% FeO, 0.15-0.73 wt.% SrO, 0.28-0.98 BaO, up to 0.43 wt.% MnO, and 0.09-0.60 Na2O. Active travertines are depleted in REE (ΣREE = 2.6-4.8 ppm) compared to the inactive ones. The Kerch travertine calcite shows unusual carbon and oxygen isotope compositions (+ 8.1 ÷ + 12.5‰ VPDB δ13C and + 10.1 ÷ + 12.9‰ VPDB δ18O). Their isotopic and trace element signatures (including REE patterns) suggest their relation to basinal waters and origin from the organic-rich clayey Maikop Fm., which is the principal source rock of the area. The Big Tarkhan travertine deposits are associated with thermogenic methane production.

  19. Innate immunity and non-Hodgkin's lymphoma (NHL related genes in a nested case-control study for gastric cancer risk.

    Directory of Open Access Journals (Sweden)

    Sue K Park

    Full Text Available OBJECTIVE: Genetic variants regulating the host immune system may contribute to the susceptibility for the development of gastric cancer. Little is known about the role of the innate immunity- and non-Hodgkin's lymphoma (NHL-related genes for gastric cancer risk. This nested case-control study was conducted to identify candidate genes for gastric cancer risk for future studies. METHODS: In the Discovery phase, 3,072 SNPs in 203 innate immunity- and 264 NHL-related genes using the Illumine GoldenGateTM OPA Panel were analyzed in 42 matched case-control sets selected from the Korean Multi-center Cancer Cohort (KMCC. Six significant SNPs in four innate immunity (DEFA6, DEFB1, JAK3, and ACAA1 and 11 SNPs in nine NHL-related genes (INSL3, CHMP7, BCL2L11, TNFRSF8, RAD50, CASP7, CHUK, CD79B, and CLDN9 with a permutated p-value <0.01 were re-genotyped in the Replication phase among 386 cases and 348 controls. Odds ratios (ORs for gastric cancer risk were estimated adjusting for age, smoking status, and H. pylori and CagA sero-positivity. Summarized ORs in the total study population (428 cases and 390 controls are presented using pooled- and meta-analyses. RESULTS: Four SNPS had no heterogeneity across the phases: in the meta-analysis, DEFA6 rs13275170 and DEFB1 rs2738169 had both a 1.3-fold increased odds ratio (OR for gastric cancer (95% CIs = 1.1-1.6; and 1.1-1.5, respectively. INSL3 rs10421916 and rs11088680 had both a 0.8-fold decreased OR for gastric cancer (95% CIs = 0.7-0.97; and 0.7-0.9, respectively. CONCLUSIONS: Our findings suggest that certain variants in the innate immunity and NHL-related genes affect the gastric cancer risk, perhaps by modulating infection-inflammation-immunity mechanisms that remain to be defined.

  20. The Relation between Globular Cluster Systems and Supermassive Black Holes in Spiral Galaxies: The Case Study of NGC 4258

    Science.gov (United States)

    González-Lópezlira, Rosa A.; Lomelí-Núñez, Luis; Álamo-Martínez, Karla; Órdenes-Briceño, Yasna; Loinard, Laurent; Georgiev, Iskren Y.; Muñoz, Roberto P.; Puzia, Thomas H.; Bruzual A., Gustavo; Gwyn, Stephen

    2017-02-01

    We aim to explore the relationship between globular cluster total number, {N}{GC}, and central black hole mass, M •, in spiral galaxies, and compare it with that recently reported for ellipticals. We present results for the Sbc galaxy NGC 4258, from Canada–France–Hawaii Telescope data. Thanks to water masers with Keplerian rotation in a circumnuclear disk, NGC 4258 has the most precisely measured extragalactic distance and supermassive black hole mass to date. The globular cluster (GC) candidate selection is based on the ({u}* -{i}\\prime ) versus ({i}\\prime -{K}s) diagram, which is a superb tool to distinguish GCs from foreground stars, background galaxies, and young stellar clusters, and hence can provide the best number counts of GCs from photometry alone, virtually free of contamination, even if the galaxy is not completely edge-on. The mean optical and optical-near-infrared colors of the clusters are consistent with those of the Milky Way and M 31, after extinction is taken into account. We directly identify 39 GC candidates; after completeness correction, GC luminosity function extrapolation, and correction for spatial coverage, we calculate a total {N}{GC}=144+/- {31}-36+38 (random and systematic uncertainties, respectively). We have thus increased to six the sample of spiral galaxies with measurements of both M • and {N}{GC}. NGC 4258 has a specific frequency {S}{{N}}=0.4+/- 0.1 (random uncertainty), and is consistent within 2σ with the {N}{GC} versus M • correlation followed by elliptical galaxies. The Milky Way continues to be the only spiral that deviates significantly from the relation.

  1. The impact of stakeholder values and power relations on community-based health insurance coverage: qualitative evidence from three Senegalese case studies.

    Science.gov (United States)

    Mladovsky, Philipa; Ndiaye, Pascal; Ndiaye, Alfred; Criel, Bart

    2015-07-01

    Continued low rates of enrolment in community-based health insurance (CBHI) suggest that strategies proposed for scaling up are unsuccessfully implemented or inadequately address underlying limitations of CBHI. One reason may be a lack of incorporation of social and political context into CBHI policy. In this study, the hypothesis is proposed that values and power relations inherent in social networks of CBHI stakeholders can explain levels of CBHI coverage. To test this, three case studies constituting Senegalese CBHI schemes were studied. Transcripts of interviews with 64 CBHI stakeholders were analysed using inductive coding. The five most important themes pertaining to social values and power relations were: voluntarism, trust, solidarity, political engagement and social movements. Analysis of these themes raises a number of policy and implementation challenges for expanding CBHI coverage. First is the need to subsidize salaries for CBHI scheme staff. Second is the need to develop more sustainable internal and external governance structures through CBHI federations. Third is ensuring that CBHI resonates with local values concerning four dimensions of solidarity (health risk, vertical equity, scale and source). Government subsidies is one of the several potential strategies to achieve this. Fourth is the need for increased transparency in national policy. Fifth is the need for CBHI scheme leaders to increase their negotiating power vis-à-vis health service providers who control the resources needed for expanding CBHI coverage, through federations and a social movement dynamic. Systematically addressing all these challenges would represent a fundamental reform of the current CBHI model promoted in Senegal and in Africa more widely; this raises issues of feasibility in practice. From a theoretical perspective, the results suggest that studying values and power relations among stakeholders in multiple case studies is a useful complement to traditional health

  2. How do plant communities and flower visitors relate? A case study of semi-natural xerothermic grasslands

    Directory of Open Access Journals (Sweden)

    Damian Chmura

    2013-06-01

    Full Text Available The paper examines the relationships between the species composition of flower visitors and plants in the semi-natural xerothermic grasslands in southern and central Poland. Thirty 10 × 10 m permanent plots were laid out in total, mainly in nature reserves. The vegetation units studied were classified according to the Braun-Blanquet system; these were phytocoenoses of the Festuco-Brometea classes Inuletum ensifoliae, Adonido-Brachypodietum pinnati and the transitional plant community. Entomological research was performed using the Pollard method within the same plots. A particular site was visited only once and different sites were studied between April and August 2008. We applied, among others, co-correspondence-analysis Co-CA, detrended correspondence analysis (DCA and redundancy analysis (RDA to investigate the co-occurrence patterns of plants and flower visitors and their biotopic requirements. We found that the species composition of flower visitors cannot be predicted by floristic composition when the duration of the study is restricted to one day (but under similar weather conditions; however, there is a positive relationship between the species richness of insects and plants and a positive relationship between the number of plant species and the abundance of flower visitors. The Ellenberg moisture index and the cover of meadow species significantly explained the species composition of insects. The three various vegetation units and five dominant xerothermic species, i.e. Adonis vernalis, Anemone sylvestris, Inula ensifolia, Linum hirsutum and Carlina onopordifolia that were studied across time differed in the species richness of insects. Our results demonstrate that possible patterns in the species composition and the assembly rules of flower visitors are not apparent when the Pollard method is applied. Based on the data obtained using this method, the flower visiting assemblages seem not to be driven by competition and they primarily

  3. Is the desire for amputation related to disturbed emotion processing? A multiple case study analysis in BIID.

    Science.gov (United States)

    Bottini, Gabriella; Brugger, Peter; Sedda, Anna

    2015-01-01

    Body integrity identity disorder (BIID) is characterized by the overwhelming desire to amputate one or more healthy limbs or to be paraplegic. Recently, a neurological explanation of this condition has been proposed, in part on the basis of findings that the insular cortex might present structural anomalies in these individuals. While these studies focused on body representation, much less is known about emotional processing. Importantly, emotional impairments have been found in psychiatric disorders, and a psychiatric etiology is still a valid alternative to purely neurological accounts of BIID. In this study, we explored, by means of a computerized experiment, facial emotion recognition and emotional responses to disgusting images in seven individuals with BIID, taking into account their clinical features and investigating in detail disgust processing, strongly linked to insular functioning. We demonstrate that BIID is not characterized by a general emotional impairment; rather, there is a selectively reduced disgust response to violations of the body envelope. Taken together, our results support the need to explore this condition under an interdisciplinary perspective, taking into account also emotional connotations and the social modulation of body representation.

  4. De termine the Relation between Perception of Organization al Justice and Level of Organizational Commitment: Study Case of Teachers

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    Gamze Ay

    2014-06-01

    Full Text Available In this research the relationship between teachers’ perception of organizational justice and their organizational commitment levels was investigated. The scope of research is comprised of teachers serving in public and foundation schools affiliated with Ministry of National Education in Turkey. A sample was taken due to the difficulty in reaching study group. The teachers in study group were enrolled from Marmara, Central Anatolia, Aegean, Black Sea, Mediterranean Sea, Eastern Anatolia and Southeastern Anatolia regions. A simple coincidental sampling formula was utilized while determining the number of sample. In this research the relationship between perception of organizational justice and organizational commitment applied to 679 teachers serving in public and foundatin schools ffiliated with Ministry of National Education was analyzed through using data obtained from answers given to survey questions. As a result of research it was established that there was a significant relationship between teachers’ perception of organizational justice and organizational commitment levels, the strongest relationship was present between interactional justice and organizational commitment levels; however, there were significant relationships between perception of organizational justice and their organizational commitment levels in terms of certain demographic variables.

  5. Risk factors for alcohol-related liver injury in the island population of China: A population-based case-control study

    Institute of Scientific and Technical Information of China (English)

    Zhe Shen; You-Ming Li; Chao-Hui Yu; Yi Shen; Lei Xu; Cheng-Fu Xu; Jin-Jin Chen; Hua Ye; Gen-Yun Xu

    2008-01-01

    AIM: To investigate the association of alcohol dose,duration of drinking and obesity with abnormal alcoholrelated liver injury indicators, the prevalence of alcoholrelated liver injury in the island population of China.METHODS: Randomized multistage stratified cluster sampling from the island population of China was used in the population-based case-control study. Then interview,physical examination, laboratory assessments and ultrasonography were done.RESULTS: Daily alcohol intake≥20 g, duration of drinking ≥ 5 years and obesity were closely related to alcohol-related liver injury (P < 0.05). The odds-ratio (OR) (95% CI) was 1.965 (1.122-3.442), 3.412 (1.789-6.507) and 1.887 (1.261-2.824), respectively. The prevalence rate of alcohol-related liver injury in ≥ 20 g daily alcohol intake group and < 20 g daily alcohol intake group was 37.14% and 12.06%, respectively. The prevalence rate of alcohol-related liver injury in ≥ 5 years drinking group and < 5 years drinking group was 34.44% and 8.53%,respectively. No significant dose-response relation was found between daily alcohol intake and abnormal alcohol-related liver injury indicators as well as between duration of drinking and abnormal alcohol-related liver injury indicators. There was no significant difference in the prevalence of alcohol-related liver injury between beer drinking group and yellow rice wine drinking group,hard liquor drinking group, multiple drinking group.CONCLUSION: The risk threshold of daily alcohol intake is 20 g and duration of drinking inducing alcohol-related liver injury 5 years in the island population of China.liver injury induced by obesity should be concerned.(c)2008 WIG. All rights reserved.

  6. Can "The New Social Studies" Survive in the Public Schools?: A Case Study of the Perceptions of Significant School Related Groups Regarding Nationalistic Instruction.

    Science.gov (United States)

    Naylor, David T.

    A review and discussion of the new social studies introduces the problem of whether nationalism and patriotism are "closed areas" or if an open examination of these areas is possible in the public schools. Two sets of hypotheses, one dealing with public school educators and the other with school-related groups, were tested by administration of a…

  7. The Impact of the Crisis on Illegal Employment of Foreigners and the Related Policy - Case study: Czech Republic

    Directory of Open Access Journals (Sweden)

    Vera–Karin BRAZOVA

    2012-05-01

    Full Text Available The aim of the article is to provide a critical perspective of the public policy measures to tackle the illegal employment of foreigners in the Czech Republic taken by the Czech government in the wake of the global financial crisis. In the introductory part of the article, the problem of illegal employment of migrants in the Czech Republic is delimitated and put into a theoretical context. Based on the study of official documents as well as on expert interviews, the analysis of the changes in the public policy dealing with the problem of illegal employment is conducted. While the crisis triggered a more open public debate and brought the problem on the agenda of some core public policy actors and while new measures were taken to address the issue, some of the main underlying problems remain unaddressed. In the final part, a possible future development in the area of illegal employment of migrants is outlined, drawing on the global labor migration trends as well as on the current public policy practice in the Czech Republic.

  8. The Importance of Water Temperature Fluctuations in Relation to the Hydrological Factor. Case Study – Bistrita River Basin (Romania

    Directory of Open Access Journals (Sweden)

    Cojoc Gianina Maria

    2014-10-01

    Full Text Available The increase in most components of the climate over the past 50 years, including air and water temperature, is a real phenomenon, as attested by the numerous specialized researches according to IPCC (2013. The water temperature is one of the most important climatic components in analyzing the hydrological regime of the Bistrita River (Romania. The thermal regime of the Bistrita River basin and the frost phenomena associated with the risk factor are particularly important and frequently appear in this area. In recent years, under the Siret Water Basin Administration, this parameter was permanently monitored, so we could do an analysis, which shows that the water temperature fluctuations, influenced by air temperature, lead to the emergence of the ice jam phenomenon. The present study aims to analyze the water temperature, as compared to the air temperature, and the effect of these components on the liquid flow regime (the values were recorded at the hydrological stations on the main course of the Bistrita River. The negative effects resulted from the ice jam phenomenon require developing methods of damage prevention and defense. The frost phenomena recorded after the construction of the Bicaz dam are analyzed in this article

  9. Institutional review board challenges related to community-based participatory research on human exposure to environmental toxins: A case study

    Directory of Open Access Journals (Sweden)

    Rudel Ruthann A

    2010-07-01

    Full Text Available Abstract Background We report on the challenges of obtaining Institutional Review Board (IRB coverage for a community-based participatory research (CBPR environmental justice project, which involved reporting biomonitoring and household exposure results to participants, and included lay participation in research. Methods We draw on our experiences guiding a multi-partner CBPR project through university and state Institutional Review Board reviews, and other CBPR colleagues' written accounts and conference presentations and discussions. We also interviewed academics involved in CBPR to learn of their challenges with Institutional Review Boards. Results We found that Institutional Review Boards are generally unfamiliar with CBPR, reluctant to oversee community partners, and resistant to ongoing researcher-participant interaction. Institutional Review Boards sometimes unintentionally violate the very principles of beneficence and justice which they are supposed to uphold. For example, some Institutional Review Boards refuse to allow report-back of individual data to participants, which contradicts the CBPR principles that guide a growing number of projects. This causes significant delays and may divert research and dissemination efforts. Our extensive education of our university Institutional Review Board convinced them to provide human subjects protection coverage for two community-based organizations in our partnership. Conclusions IRBs and funders should develop clear, routine review guidelines that respect the unique qualities of CBPR, while researchers and community partners can educate IRB staff and board members about the objectives, ethical frameworks, and research methods of CBPR. These strategies can better protect research participants from the harm of unnecessary delays and exclusion from the research process, while facilitating the ethical communication of study results to participants and communities.

  10. Dance-related concussion: a case series.

    Science.gov (United States)

    Stein, Cynthia J; Kinney, Susan A; McCrystal, Tara; Carew, Elizabeth A; Bottino, Nicole M; Meehan Iii, William P; Micheli, Lyle J

    2014-01-01

    Sport-related concussion is a topic of increasing public and media attention; the medical literature on this topic is growing rapidly. However, to our knowledge no published papers have described concussion specifically in the dancer. This case series involved a retrospective chart review at a large teaching hospital over a 5.5-year period. Eleven dancers (10 female, 1 male) were identified who experienced concussions while in dance class, rehearsal, or performance: 2 in classical ballet, 2 in modern dance, 2 in acro dance, 1 in hip hop, 1 in musical theater, and 3 were unspecified. Dancers were between 12 and 20 years old at the time of presentation. Three concussions occurred during stunting, diving, or flipping. Three resulted from unintentional drops while partnering. Two followed slips and falls. Two were due to direct blows to the head, and one dancer developed symptoms after repeatedly whipping her head and neck in a choreographed movement. Time to presentation in the sports medicine clinic ranged from the day of injury to 3 months. Duration of symptoms ranged from less than 3 weeks to greater than 2 years at last documented follow-up appointment. It is concluded that dancers do suffer dance-related concussions that can result in severe symptoms, limitations in dance participation, and difficulty with activities of daily living. Future studies are needed to evaluate dancers' recognition of concussion symptoms and care-seeking behaviors. Additional work is also necessary to tailor existing guidelines for gradual, progressive, safe return to dance.

  11. Case Studies - Cervical Cancer

    Centers for Disease Control (CDC) Podcasts

    2010-10-15

    Dr. Alan Waxman, a professor of obstetrics and gynecology at the University of New Mexico and chair of the American College of Obstetricians and Gynecologists (ACOG) committee for the underserved, talks about several case studies for cervical cancer screening and management.  Created: 10/15/2010 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP), Division of Cancer Prevention and Control (DCPC).   Date Released: 6/9/2010.

  12. Exposure to traffic-related air pollution and the risk of developing breast cancer among women in eight Canadian provinces: a case-control study.

    Science.gov (United States)

    Hystad, Perry; Villeneuve, Paul J; Goldberg, Mark S; Crouse, Dan L; Johnson, Kenneth

    2015-01-01

    A few recent studies have reported positive associations between long-term exposure to traffic-related air pollution and the incidence of breast cancer. We capitalized on an existing Canadian multi-site population-based case-control study to further investigate this association. We used the National Enhanced Cancer Surveillance System, a population-based case-control study conducted in eight of 10 Canadian provinces from 1994 to 1997. A total of 1569 breast cancer cases and 1872 population controls who reported at least 90% complete self-reported addresses over the 1975-1994 exposure period were examined. Mean exposure levels to nitrogen dioxide (NO2) (an indicator of traffic-related air pollution) were estimated for this period using three different measures: (1) satellite-derived observations; (2) satellite-derived observations scaled with historical fixed-site measurements of NO2; and (3) a national land-use regression (LUR) model. Proximity to major roads was also examined. Using unconditional logistic regression, stratified by menopausal status, we estimated odds ratios (ORs) adjusted for many individual-level and contextual breast cancer risk factors. We observed positive associations between incident breast cancer and all three measures of NO2 exposure from 1975 to 1994. In fully adjusted models for premenopausal breast cancer, a 10ppb increase in NO2 exposure estimated from the satellite-derived observations, the scaled satellite-derived observations, and the national LUR model produced ORs of 1.26 (95% confidence intervals (CIs): 0.92-1.74), 1.32 (95% CI: 1.05-1.67) and 1.28 (95% CI: 0.92-1.79). For postmenopausal breast cancer, we found corresponding ORs of 1.10 (95% CI: 0.88-1.36), 1.10 (95% CI: 0.94-1.28) and 1.07 (95% CI: 0.86-1.32). Substantial heterogeneity in the ORs was observed across the eight Canadian provinces and reduced ORs were observed when models were restricted to women who had received routine mammography examinations. No associations

  13. A Comparative Study of The Regular Pattern of Syndrome and Treatment of Lung-intestine Related Diseases in Ancient and Modern Medical Cases Based on Data Mining

    Institute of Scientific and Technical Information of China (English)

    Fang-Fang Mo; Le-Peng Wang; Si-Hua Gao

    2016-01-01

    Objective: To analyze the similarities and differences of the applications of “the lung and large intestine being interior-exteriorly related”between the ancient and modern clinical practices, and to reveal the theory meaning. Method: Based on the ancient and modern medical cases database, 245 ancient medical records and 373 modern medical records were studied with the general statistical description and analysis of association rules, and the results were compared to summarize the similarities and differences of the regular pattern of syndrome and treatment on lung-large intestine related diseases in ancient and modern medical records. Results: In modern medical cases, intestinal diseases appeared with the main symptom of constipation due to deficiency of lung qi and qi stagnation of large intestine were always treated by purgation together with replenishing and restoring lung qi. In ancient medical cases, large intestine heat was always caused by lung heat and a variety of diarrhea symptoms appeared. They were always treated by clearing heat and moistening lungs. In addition, the symptom of bound stool caused by qi stagnation of large intestine due to lung qi stagnation was always treated by lowering lung qi to regulate and smooth large intestine qi. And Armeniae Amarum Semen was used by both as a core medicinal herb. Conclusion: Ascending-descending of qi movement is the core of the lung and large intestine relationship. In other words, the lung and the large intestine communicate through qi.

  14. Herd-level risk factors for bovine tuberculosis and adoption of related biosecurity measures in Northern Ireland: A case-control study.

    Science.gov (United States)

    O'Hagan, M J H; Matthews, D I; Laird, C; McDowell, S W J

    2016-07-01

    Bovine tuberculosis (bTB) is a zoonotic disease which is endemic in Northern Ireland. As it has proven difficult to eradicate this disease, partly due to a wildlife reservoir being present in the European badger (Meles meles), a case-control study was conducted in a high incidence area in 2010-2011. The aim was to identify risk factors for bTB breakdown relating to cattle and badgers, and to assess the adoption of bTB related biosecurity measures on farms. Face-to-face questionnaires with farmers and surveys of badger setts and farm boundaries were conducted on 117 farms with a recent bTB breakdown (cases) and 75 farms without a recent breakdown (controls). On logistic regression at univariable and multivariable levels, significant risk factors associated with being a case herd included having an accessible badger sett within the farm boundaries in a field grazed in the last year (odds ratio, OR, 4.14; 95% confidence interval, CI, 1.79, 9.55), observation of live badgers (OR 4.14; 95% CI 1.79, 9.55), purchase of beef cattle (OR 4.60; 95% CI 1.61, 13.13), use of contractors to spread slurry (OR 2.83; 95% CI 1.24, 6.49), feeding meal on top of silage (OR 3.55; 95% CI 1.53, 8.23) and feeding magnesium supplement (OR = 3.77; 95% CI 1.39, 10.17). The majority of setts within the farm boundary were stated to be accessible by cattle (77.1%; 95% CI 71.2, 83.0%) and 66.8% (95% CI 63.8, 69.7%) of farm boundaries provided opportunities for nose-to-nose contact between cattle. Adoption of bTB related biosecurity measures, especially with regards to purchasing cattle and badger-related measures, was lower than measures related to disinfection and washing.

  15. Case-control study on beneficial effect of regular consumption of apples on colorectal cancer risk in a population with relatively low intake of fruits and vegetables.

    Science.gov (United States)

    Jedrychowski, Wieslaw; Maugeri, Umberto; Popiela, Tadeusz; Kulig, Jan; Sochacka-Tatara, Elzbieta; Pac, Agnieszka; Sowa, Agata; Musial, Agnieszka

    2010-01-01

    Laboratory in-vitro studies and animal experiments showing the potential health benefits from apples raises the question to what extent the regular consumption of apples in humans may have a beneficial effect on colorectal cancer risk. A total of 592 incident cases of colorectal cancer have been enrolled in a hospital-based case-control study. The comparison group included 765 controls chosen from the patients of the same hospital without history of cancer and admitted for treatment of nonneoplastic conditions. Interviews of both cases and controls were conducted in the hospital setting by trained interviewers. The median intake of fruits among cases was lower than in controls (9.5 vs. 11 servings/week) and the difference was statistically significant. Apples were the most frequent fruit consumed by the study participants and about 80% of variability in the total fruit consumption resulted from the intake of apples. We did not observe any significant statistical differences in consumption of berries, citrus, or stone fruits and other kinds of fruits across cases and controls. The adjusted estimates of colorectal cancer risk related to the daily consumption of apples (in quintiles) were based on the unconditional multivariate logistic model, which considered the set of potential confounding variables such as demographic characteristics of participants (age, gender, place of residency, marital status, tobacco smoking), total energy intake, intake of vegetables and fruits without apples. The results of the logistic analysis showed that the adjusted risk of colorectal cancer inversely correlated with daily number of apple servings. The reduced risk of colorectal cancer of border significance level was already observed at the consumption of at least one apple a day (odds ratio=0.65, 95% CI: 0.39-1.09), but at the intake of more than one apple a day the risk was reduced by about 50% (odds ratio=0.53, 95% CI: 0.35-0.79). Neither the consumption of vegetables nor other

  16. Risk factors related to female breast cancer in regions of Northeast China: a 1:3 matched case-control population-based study

    Institute of Scientific and Technical Information of China (English)

    YU Zhi-gang; JIA Cun-xian; GENG Cui-zhi; TANG Jin-hai; ZHANG Jin; LIU Li-yuan

    2012-01-01

    Background There has been an increase in the incidence of breast cancer in China,but no definite risk and protective factors for breast cancer have been identified in Chinese females.This study was designed to identify the risk factors for female breast cancer in North and East China.Methods A 1:3 matched,case-control study was conducted.All of the subjects in the case and control groups were selected from a previous epidemiological survey of 122 058 females aged 25 to 70 years.Single and multiple Logistic regression analyses were used to study potential factors in the development of breast cancer.Results Significant differences at the level of α=0.20 between case and control groups were observed for the following factors:economic status,social status,family annual income,bean product consumption,body mass index (BMI),family history of breast cancer in the first or second degree,number of miscarriages,menstrual pattern,benign breast disease history,nipple leakage,inverted nipple,history of diabetes mellitus,history of hypertension,history of ovarian cyst,physical exercise,current and global quality of life satisfaction,healthy behavior and prevention,and scores of breast cancer-related knowledge.After Cox-regression model analysis (α=0.10),six factors were found to be significantly related to breast cancer,of which the ORs and 95%C/s were:BMI,1.696 (1.169-2.460,P=0.005); benign breast disease history,2.672 (0.848-8.416,P=0.093); family history of breast cancer,7.080 (1.758-28.551,P=0.006); number of miscarriages,1.738 (1.014-2.978,P=0.044); global quality of life satisfaction,3.044 (1.804-5.136,P=0.000); healthy behavior and prevention,3.294 (1.692-6.412,P=0.000).Conclusions A comprehensive range of factors related to breast cancer was identified.Women should be educated about a healthy lifestyle,especially those with a family history of breast cancer or a personal history of benign breast disease.

  17. A Study of the Social Construction of Work-Related Accidents “A Case study: workers of the coal mines of Koohbanan in Kerman and Tabas”

    Directory of Open Access Journals (Sweden)

    M. Movahed Majd

    2015-05-01

    Full Text Available In safety sciences, accidents are unintended and non-scheduled events happening as one or more consecutive incidents as a result of unsafe acts or unsafe conditions, or both. Despite growing improvements in safety sciences in recent decades, the concept of accident, as a non-social phenomenon, is defined as neutral and meaningless, which occurs in an unintended and non-scheduled way through workers or machines. A significant amount of the research carried out in this field, following the tradition of epidemiology and behavioral psychology and by reducing the problem of safety and work health to a technical issue, emphasizes the role of individuals’ risk factors and human error in the occurrence of accidents. These studies neglect social, economic, cultural and institutional contexts in the analysis of accidents and take no advantage of interdisciplinary findings, as a result of which such reports only provide a list of risk factors and the statistical distribution of events in terms of quantitative and demographic variables; thus, they disregard the process of the social construction of accidents and the problematic nature of the concept of accidents. Therefore, the present study intends to expose the limitations of safety sciences and its conventional technical approaches in the unilateral and one-dimensional explanation of work-related accidents. For this purpose, in this research, qualitative methodology has been used as the dominant methodology, and critical ethnography has been utilized for the research process, and also thematic analysis has been employed for data analysis. The findings of the study include seven main categories which are shown in the form of the social construction cycle of accidents. Finally, the results show that work-related accidents are mainly due to the conditions governing the organization, unequal power relations and workers’ experiences of work environment than carelessness and the individual and

  18. Prostate Cancer Risk in Relation to IGF-1 and its Genetic Determinants: A Case Control Study Within the Cancer Prostate Sweden Project (CAPS)

    Science.gov (United States)

    2006-05-01

    I and its Genetic Determinants: A Case Control Study within the Cancer Prostate Sweden Project (CAPS) PRINCIPAL INVESTIGATOR: Rudolf J...Genetic Determinants: A Case Control Study within the Cancer Prostate Sweden Project (CAPS) 5b. GRANT NUMBER DAMD17-03-1-0374 5c. PROGRAM ELEMENT

  19. Background: GIS Applications and Case Studies

    OpenAIRE

    01, CCTP; Albert, Don

    1998-01-01

    This unit presents (1) a case study and (2) a bibliographic resource for GIS in the medical field. The case study illustrates the use of a GIS to monitor and analyze spatial patterns of physicians' multiple locations. This case highlights data location, acquisition and assessment, join and relational operators, geocoding and distance calculations, and standard query language.

  20. Prevalence of enteroaggregative Escherichia coli and its virulence-related genes in a case-control study among children from north-eastern Brazil.

    Science.gov (United States)

    Lima, Ila Fernanda Nunes; Boisen, Nadia; Quetz, Josiane da Silva; Havt, Alexandre; de Carvalho, Eunice Bobo; Soares, Alberto Melo; Lima, Noélia Leal; Mota, Rosa Maria Salani; Nataro, James P; Guerrant, Richard Littleton; Lima, Aldo Ângelo Moreira

    2013-05-01

    Enteroaggregative Escherichia coli (EAEC) is an important agent that causes endemic and epidemic diarrhoeal diseases worldwide. Several EAEC virulence-related genes (VRGs) have been described but their role in the clinical outcome of infection is not completely defined. This study investigated the prevalence of EAEC and potential associations of its VRGs with risk of or protection from diarrhoeal diseases in children from urban communities in north-eastern Brazil. The case-control study included 166 children, who had their stools evaluated for the EAEC diagnostic genes (aaiC and aatA) using PCR. Positive samples were further analysed by multiplex PCR and identified 18 VRGs. EAEC was found in the same proportion in both groups (41%). The plasmid-borne gene encoding a hexosyltransferase homologue (capU) was the most frequently detected (89.6%), followed by dispersin protein (aap, 58.2%) and EAEC HilA homologue (eilA, 57.8%). The AAF/III fimbrial subunit (agg3A) gene was observed at lower frequency (1.5%). Plasmid-encoded toxin (pet) or AAF/II fimbrial subunit (aafA) was associated significantly with disease. AAF/IV fimbrial subunit (agg4A) or hypothetical plasmid-encoded haemolysin (orf61) was detected significantly more in controls than in children with diarrhoea. In addition, one set of genes in combination, aaiC and agg3/4C but lacking agg4A and orf61, was associated with diarrhoea cases; and another one, orf61 in the absence of pet and aafA, was correlated with control children. These data confirm a high prevalence, endemicity and heterogeneity of EAEC strains in the developing urban areas of north-eastern Brazil. Statistical correlation between cases and controls was seen with either isolated or combined sets of genes, suggesting that the pathophysiology of EAEC infection involves a complex and dynamic modulation of several VRGs.

  1. A clinico-radiological study on 254 cases of pontine high signals on magnetic resonance imaging in relation to brain stem semiology

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, Masaki; Takahashi, Akira (Nagoya Univ. (Japan). Faculty of Medicine); Arahata, Yutaka; Motegi, Yoshimasa; Furuse, Masahiro

    1993-11-01

    A total of 254 patients who were proved to have pontine high intensity areas on T[sub 2]-weighted magnetic resonance imaging (MRI) were analyzed in relation to brain stem semiology. A comparative study on MRI and MR angiography was made between 254 patients with pontine high signals and 276 control cases showing no abnormality either on T[sub 1] or T[sub 2]-weighted images. Of the 254 patients, 62 had transient subjective complaints such as vertigo-dizziness. Supratentorial high signals, basilar artery tortuousness and vertebral artery asymmetry on MR angiography were seen more frequently in patients with pontine high signals than in the controls. In conclusion, pontine high signals may result from diffuse arteriosclerosis and MR angiography is considered to be a useful screening method. (author).

  2. A 3' UTR SNP in COL18A1 is associated with susceptibility to HBV related hepatocellular carcinoma in Chinese: three independent case-control studies.

    Directory of Open Access Journals (Sweden)

    Xiaopan Wu

    Full Text Available BACKGROUND: Accumulated evidences indicate that single nucleotide polymorphisms (SNP in angiogenesis and tumorigenesis related genes are associated with risk of Hepatocellular carcinoma (HCC. COL18A1 encodes the precursor of endostatin, which is a broad-spectrum angiogenesis inhibitor, and we speculate that SNPs in COL18A1 may be associated with susceptibility to HCC. METHODS AND FINDINGS: We carried out a 2-stage association study in 3 independent case-control groups in a total of 1067 chronic hepatitis B (CHB patients and 808 hepatitis B virus (HBV related HCC patients in Han Chinese. Four SNPs which can represent all potential functional SNPs with MAF>0.1 recorded in HapMap database were genotyped using TaqMan methods. Levels of total COL18A1 mRNA were also examined using quantitative real-time RT-PCR. We found that rs7499 located in 3'-UTR to be strongly associated with HBV related HCC (P(combined = 0.0000005, OR = 0.72, 95%CI = 0.63-0.82. COL18A1 mRNA expression was significantly decreased as the disease progressed (P = 0.000026. CONCLUSION: These findings indicate that COL18A1 rs7499 may contribute to the risk of HCC in Han Chinese.

  3. Number of addictive substances used related to increased risk of unnatural death: A combined medico-legal and case-record study

    Directory of Open Access Journals (Sweden)

    Lindgren Anna

    2009-08-01

    Full Text Available Abstract Background Substance use disorders have repeatedly been found to lead to premature death, i.e. drug-related death by disease, fatal intoxications, or trauma (accidents, suicide, undetermined suicide, and homicide. The present study examined the relationship between multi-drug substance use and natural and unnatural death. Methods All consecutive, autopsied patients who had been in contact with the Addiction Centre in Malmö University Hospital from 1993 to 1997 inclusive were investigated. Drug abuse was investigated blindly in the case records and related to the cause of death in 387 subjects. Results Every substance apart from alcohol used previously in life added to the risk of unnatural death in a linear way. There were independent increased risks of fatal heroin overdoses or undetermined suicide. Death by suicide and violent death were unrelated to additional abuse. Conclusion The number of drugs used was related to an increased risk of unnatural death by undetermined suicide (mainly fatal intoxications and heroin overdose.

  4. The incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of cardiac surgery patients: a prospective nested case-control study.

    Science.gov (United States)

    Vlaar, Alexander P J; Hofstra, Jorrit J; Determann, Rogier M; Veelo, Denise P; Paulus, Frederique; Kulik, Wim; Korevaar, Johanna; de Mol, Bas A; Koopman, Marianne M W; Porcelijn, Leendert; Binnekade, Jan M; Vroom, Margreeth B; Schultz, Marcus J; Juffermans, Nicole P

    2011-04-21

    Transfusion-related acute lung injury (TRALI) is the leading cause of transfusion-related morbidity and mortality. Both antibodies and bioactive lipids that have accumulated during storage of blood have been implicated in TRALI pathogenesis. In a single-center, nested, case-control study, patients were prospectively observed for onset of TRALI according to the consensus definition. Of 668 patients, 16 patients (2.4%) developed TRALI. Patient-related risk factors for onset of TRALI were age and time on the cardiopulmonary bypass. Transfusion-related risk factors were total amount of blood products (odds ratio [OR] = 1.2; 95% confidence interval [CI], 1.03-1.44), number of red blood cells stored more than 14 days (OR = 1.6; 95% CI, 1.04-2.37), total amount of plasma (OR = 1.2; 95% CI, 1.03-1.44), presence of antibodies in donor plasma (OR = 8.8; 95% CI, 1.8-44), and total amount of transfused bioactive lipids (OR = 1.0; 95% CI, 1.00-1.07). When adjusted for patient risk factors, only the presence of antibodies in the associated blood products remained a risk factor for TRALI (OR = 14.2; 95% CI, 1.5-132). In-hospital mortality of TRALI was 13% compared with 0% and 3% in transfused and nontransfused patients, respectively (P < .05). In conclusion, the incidence of TRALI is high in cardiac surgery patients and associated with adverse outcome. Our results suggest that cardiac surgery patients may benefit from exclusion of blood products containing HLA/HNA antibodies.

  5. A case of trauma related Acanthamoeba keratitis.

    Science.gov (United States)

    Kamel, A G M; Faridah, H; Yusof, S; Norazah, A; Nakisah, M A

    2004-12-01

    Acanthamoeba is an uncommon cause of keratitis but one of the most severe because of the prolonged and painful course of the disease and poor visual outcome. Although contact lens use is the principal risk factor, about 10% of cases occur following trauma and exposure to contaminated soil or water. Two cases of Acanthamoeba keratitis involving women contact lens wearers have previously been reported in Malaysia but this is the first time, a non contact lens related Acanthamoeba keratitis is reported. The case involved a 28 year old Indonesian male construction worker who had a trauma of the right eye during work. His eye was struck by sand and dust particles after which he quickly washed with water from an open tank at the construction site. He experienced pain, redness, glaring and blurring of vision of the right eye three days later. The diagnosis was missed at initial presentation but culture of the corneal scraping had proven Acanthamoeba as the aetiological agent. The history and clinical findings of this trauma related Acanthamoeba keratitis are briefly discussed.

  6. Interaction between interleukin-10 (IL-10 polymorphisms and dietary fibre in relation to risk of colorectal cancer in a Danish case-cohort study

    Directory of Open Access Journals (Sweden)

    Andersen Vibeke

    2012-05-01

    Full Text Available Abstract Background More than 50% of the colorectal cancer (CRC etiology has been attributed to diet. Established or suspected dietary factors modifying risk of CRC are red meat, cereals, fish, and fibre. Diet and lifestyle may be linked to cancer through inflammation. Interleukin-10 (IL-10 is an anti-inflammatory cytokine. We wanted to test if dietary factors and IL10 polymorphisms interact in relation to colorectal carcinogenesis. Methods The functional IL10 polymorphism C-592A (rs1800872 and the marker rs3024505 were assessed in relation to diet and lifestyle in a nested case-cohort study of 378 CRC cases and 775 randomly selected participants from a prospective study of 57,053 persons. Genotyping data on the IL10 polymorphism C-592A, smoking and non-steroidal anti-inflammatory drugs (NSAID was retrieved from Vogel et al. (Mutat Res, 2007; 624:88. Incidence rate ratios (IRR and 95% Confidence Interval (95% CI were calculated. Results No associations were found between the IL10 rs3024505 polymorphism and risk of CRC. There was interaction between rs3024505 and dietary fibre (P-value for interaction = 0.01. IL10 rs3024505 homozygous wildtype carriers were at 27% reduced risk of CRC per 10 g fibre per day (95% CI: 0.60-0.88 whereas variant carriers had no risk reduction by fibre intake. Also, interaction between IL10 C-592A and intake of fibre was found (P-value for interaction = 0.02. Among those eating IL10 polymorphisms and dietary meat, cereal, or fish intake, or between IL10 rs3024505 and smoking or NSAID use were found. Conclusions In this northern Caucasian cohort we found interaction between IL10 and dietary fibre in CRC carcinogenesis. High intake of fibre seems to protect against CRC among individuals with IL10 related genetic susceptibility to CRC. This finding should be evaluated in other prospective and population-based cohorts with different ethnic groups.

  7. Mining literature for a comprehensive pathway analysis: A case study for retrieval of homocysteine related genes for genetic and epigenetic studies

    Directory of Open Access Journals (Sweden)

    Mahajan Anubha

    2006-01-01

    Full Text Available Abstract Homocysteine is an independent risk factor for cardiovascular diseases. It is also known to be associated with a variety of complex disorders. While there are a large number of independent studies implicating homocysteine in isolated pathways, the mechanism of homocysteine induced adverse effects are not clear. Homocysteine-induced modulation of gene expression through alteration of methylation status or by hitherto unknown mechanisms is predicted to lead to several pathological conditions either directly or indirectly. In the present manuscript, using literature mining approach, we have identified the genes that are modulated directly or indirectly by an elevated level of homocysteine. These genes were then placed in appropriate pathways in an attempt to understand the molecular basis of homocysteine induced complex disorders and to provide a resource for selection of genes for polymorphism screening and analysis of mutations as well as epigenetic modifications in relation to hyperhomocysteinemia. We have identified 135 genes in 1137 abstracts that either modulate the levels of homocysteine or are modulated by elevated levels of homocysteine. Mapping the genes to their respective pathways revealed that an elevated level of homocysteine leads to the atherosclerosis either by directly affecting lipid metabolism and transport or via oxidative stress and/or Endoplasmic Reticulum (ER stress. Elevated levels of homocysteine also decreases the bioavailability of nitric oxide and modulates the levels of other metabolites including S-adenosyl methionine and S-adenosyl homocysteine which may result in cardiovascular or neurological disorders. The ER stress emerges as the common pathway that relates to apoptosis, atherosclerosis and neurological disorders and is modulated by levels of homocysteine. The comprehensive network collated has lead to the identification of genes that are modulated by homocysteine indicating that homocysteine exerts its

  8. Nearly Zero Energy Standard for Non-Residential Buildings with high Energy Demands—An Empirical Case Study Using the State-Related Properties of BAVARIA

    Directory of Open Access Journals (Sweden)

    Michael Keltsch

    2017-03-01

    Full Text Available The Energy Performance of Buildings Directive (EPBD 2010 calls for the Nearly Zero Energy Building (nZEB Standard for new buildings from 2021 onwards: Buildings using “almost no energy” are powered by renewable sources or by the energy produced by the building itself. For residential buildings, this ambitious new standard has already been reached. But for other building types, this goal is still far away. The potential of these buildings to meet a nZEB Standard was investigated by analyzing ten case studies, representing non-residential buildings with different uses. The analysis shows that the primary characteristics common to critical building types are a dense building context with a very high degree of technical installation (such as hospital, research, and laboratory buildings. The large primary energy demand of these types of buildings cannot be compensated by building- and property-related energy generation, including off-site renewables. If the future nZEB Standard were to be defined with lower requirements because of this, the state-related properties of Bavaria suggest that the real potential energy savings available in at least 85% of all new buildings would be insufficiently exploited. Therefore, it would be more useful to individualize the legal energy verification process for new buildings, to distinguish critical building types such as laboratories and hospitals from the other building types.

  9. Common immune-related exposures/conditions and risk of non-Hodgkin lymphoma: a case-control study of disease-discordant twin pairs.

    Science.gov (United States)

    Wang, Jun; Mack, Thomas M; Hamilton, Ann S; Hwang, Amie E; Nathwani, Bharat N; Masood, Kamil; Buchanan, Laura H; Bernstein, Leslie; Deapen, Dennis M; Martínez-Maza, Otoniel; Cozen, Wendy

    2015-09-01

    We evaluated the association between common immune system-altering experiences and non-Hodgkin lymphoma (NHL) risk using a case-control study of 162 like-sex twin pairs discordant for NHL, identified from the International Twin Study. Information on medical history and evidence of childhood exposure to microbes was obtained by questionnaire from 1998 to 2002. Conditional logistic regression was used to estimate odds ratios and 95% confidence intervals. Intra-twin-pair agreement between twins on individual exposures was high (76%-97%). A negative association between NHL and seasonal hay fever (odds ratio (OR) = 0.28, 95% confidence interval (CI): 0.10, 0.75) and certain allergies (OR = 0.29, 95% CI: 0.13, 0.68) was observed. The number of atopic diseases was negatively associated with NHL (P for trend = 0.0003). A history of infectious mononucleosis was negatively associated with NHL risk (OR = 0.35, 95% CI: 0.14, 0.90). NHL risk was associated with more frequent childhood exposure to microbes during early life (P for trend = 0.04). No differences in association by NHL subtype were observed, although statistical power for these comparisons was low. These observations support the hypothesis that immune-related exposures, especially atopy, are associated with decreased NHL risk. Use of the within-twin-pair study design mitigates confounding by genome, family structure, and unmeasured characteristics of early childhood factors.

  10. Demystifying Instructional Innovation: The Case of Teaching with Case Studies

    Science.gov (United States)

    Kantar, Lina D.

    2013-01-01

    Issues emerging from instructional innovation are inevitable, yet basing any curriculum shift on a theoretical framework is paramount. This paper grounds the case-based pedagogy in three learning theories: behaviorism, cognitivism, and constructivism. The three theories are described and situated in relation to the case study method. An…

  11. In-vivo visualisation of the anatomical structures related to the acupuncture points Dai mai and Shen mai by MRI: A single-case pilot study

    Directory of Open Access Journals (Sweden)

    Diemling Markus

    2007-03-01

    Full Text Available Abstract Background The concept of acupuncture point localisation in Traditional Chinese Medicine (TCM is based on millenary practical experience. Modern imaging methods such as PET, MRI and SPECT have been used primary for the investigation of the mechanisms of action of acupuncture. In this pilot single-case study we have evaluated the technical possibilities for in-vivo imaging of the anatomical relations of acupuncture points using state of the art MRI. Methods Preliminary experiments relating to the quality of acupuncture needles under the setting of MRI were done both with stainless steel and gold needles. In a second step, in-vivo imaging was carried out. A licensed acupuncture practitioner (RM chose two points belonging to the so-called extraordinary vessels. In 2 sequential, separate procedures, he inserted himself gold acupuncture needles using a neutral technique (known as Ping Bu Ping Xie into the Dai mai and Shen mai points, i.e. gall bladder 26 and bladder 62. Imaging was done on a Siemens Magnetom Avanto MR scanner using a head array and body coil. Mainly T1-weighted imaging sequences, as routinely used for patient exams, were used to obtain multi-slice images. Results In the preliminary experiments only acupuncture needles made of gold showed enough stability in order to be used for further imaging procedures. Using an onion and a banana as an object, further studies showed that the gold needles produced a void defect that corresponds to the tip of the inserted needle, while at the same time an artefactually increased diameter was observed. The in-vivo experiments showed that the Dai mai point was in relation to the abdominal internal oblique muscle. The Shen mai point artefact showed up close to the longus and brevis peroneal tendons at the fibular malleolus. Side effects related to heating or burning were not observed. Improved anatomical recognition was obtained using 3D-volume rendering techniques. Conclusion Through an

  12. Avalanche related damage potential - changes of persons and mobile values since the mid-twentieth century, case study Galtür

    Directory of Open Access Journals (Sweden)

    M. Keiler

    2005-01-01

    Full Text Available When determining risk related to natural hazard processes, many studies neglect the investigations of the damage potential or are limited to the assessment of immobile values like buildings. However, persons as well as mobile values form an essential part of the damage potential. Knowledge of the maximum number of exposed persons in an endangered area is of great importance for elaborating evacuation plans and immediate measures in case of catastrophes. In addition, motor vehicles can also be highly damaged, as was shown by the analysis of avalanche events. With the removal of mobile values in time as a preventive measure this kind of damage can be minimised. This study presents a method for recording the maximum number of exposed persons and monetarily assessing motor vehicles in the municipality of Galtür (Tyrol, Austria. Moreover, general developments of the damage potential due to significant socio-economic changes since the mid-twentieth century are pointed out in the study area. The present situation of the maximum number of persons and mobile values in the official avalanche hazard zones of the municipality is described in detail. Information on the number of persons is derived of census data, tourism and employment statistics. During the winter months, a significant increase overlaid by strong short-term fluctuation in the number of persons can be noted. These changes result from a higher demand of tourism related manpower as well as from varying occupancy rates. The number of motor vehicles in endangered areas is closely associated to the number of exposed persons. The potential number of motor vehicles is investigated by means of mapping, statistics on the stock of motor vehicles and the density distribution. Diurnal and seasonal fluctuations of the investigated damage potential are pointed out. The recording of the number of persons and mobile values in endangered areas is vital for any disaster management.

  13. Differential haemostatic risk factors for pregnancy-related deep-vein thrombosis and pulmonary embolism: a population-based case-control study.

    Science.gov (United States)

    Bergrem, Astrid; Dahm, Anders E A; Jacobsen, Anne Flem; Sandvik, Leiv; Sandset, Per Morten

    2012-12-01

    Limited data exist on thrombophilia and the risk of venous thrombosis (VT) during pregnancy and postpartum. The objectives of the present study were to investigate the role of haemostatic risk factors for pregnancy-related VT and their phenotypic expression in deep-vein thrombosis (DVT) and pulmonary embolism (PE). Total 313 cases with objectively verified first time VT and 353 controls were selected from a source population of 377,155 women with 613,232 pregnancies. The adjusted odds ratio (aOR) for pregnancy-related VT was 1.7 (95% confidence interval [CI] 1.1-2.8) for women with factor VIII >90th percentile. The aOR for VT for endogenous thrombin potential and D-dimer values >90th percentiles were 1.8 (95% CI 1.1-3.0) and 2.1 (95% CI 1.3-3.3), respectively. Factor IX >90th percentile or free protein S ≤the 5th percentile increased the risk for PE, and the aORs were 2.4 (95% CI 1.1-5.0) and 3.1 (95% CI 1.3-7.2), respectively. Women carrying the factor V Leiden (F5 rs6025) polymorphism, or who had reduced sensitivity to activated protein C (aPC) in the absence of F5 rs6025, had increased risk for DVT, with unadjusted ORs 7.7 (95% CI 4.7-12.7) and 3.5 (95% CI 2.2-5.4), respectively. Women with a history of pregnancy-related VT showed activation of coagulation and had elevated factor VIII. Furthermore, high levels of factor IX and low levels of free protein S were associated with increased risk for PE, whereas aPC resistance and F5 rs6025 were risk factors for DVT and not PE.

  14. Intersectorial health-related policies: the use of a legal and theoretical framework to propose a typology to a case study in a Brazilian municipality.

    Science.gov (United States)

    Tess, Beatriz Helena; Aith, Fernando Mussa Abujamra

    2014-11-01

    This article analyzes intersectorial health-related policies (IHRP) based on a case study performed in 2008-2009 that mapped the social policies of the city of Piracicaba, State of Sao Paulo, Brazil. The research strategy comprised quantitative and qualitative methodologies and converging information sources. Legal and theoretical conceptual frameworks were applied to the Piracicaba study results and served as the basis for proposing a typology of IHRP. Three types of IHRP were identified: health policies where the health sector is coordinator but needs non-health sectors to succeed; policies with a sector other than health as coordinator, but which needs health sector collaboration to succeed; and thirdly, genuine intersectorial policies, not led by any one sector but by a specifically-appointed intersectorial coordinator. The authors contend that political commitment of local authorities alone may not be enough to promote efficient intersectorial social policies. Comprehension of different types of IHRP and their interface mechanisms may contribute to greater efficiency and coverage of social policies that affect health equity and its social determinants positively. In the final analysis,, this will lead to more equitable health outcomes.

  15. Intersectorial health-related policies: the use of a legal and theoretical framework to propose a typology to a case study in a Brazilian municipality

    Directory of Open Access Journals (Sweden)

    Beatriz Helena Tess

    2014-11-01

    Full Text Available This article analyzes intersectorial health-related policies (IHRP based on a case study performed in 2008-2009 that mapped the social policies of the city of Piracicaba, State of Sao Paulo, Brazil. The research strategy comprised quantitative and qualitative methodologies and converging information sources. Legal and theoretical conceptual frameworks were applied to the Piracicaba study results and served as the basis for proposing a typology of IHRP. Three types of IHRP were identified: health policies where the health sector is coordinator but needs non-health sectors to succeed; policies with a sector other than health as coordinator, but which needs health sector collaboration to succeed; and thirdly, genuine intersectorial policies, not led by any one sector but by a specifically-appointed intersectorial coordinator. The authors contend that political commitment of local authorities alone may not be enough to promote efficient intersectorial social policies. Comprehension of different types of IHRP and their interface mechanisms may contribute to greater efficiency and coverage of social policies that affect health equity and its social determinants positively. In the final analysis,, this will lead to more equitable health outcomes.

  16. Program evaluation and case study

    OpenAIRE

    Kushner, S

    2009-01-01

    This entry looks at the convergence of case study methodology and program evaluation. An early insight of some educational evaluation theorists was of the convergence of case study and program evaluation – the fusion of method with purpose. Program evaluation and case study came to be mutually-bracketed. In the educational evaluation field 'Responsive', 'Democratic', 'Illuminative' methodologies were developed in parallel with case study methods - the same authors contributing freely to both ...

  17. Environmental and Psycho-social Factors Related to Prostate Cancer Risk in the Chinese Population:a Case-control Study

    Institute of Scientific and Technical Information of China (English)

    LI Mei Ling; GUO Jian Ming; XU Dan Feng; THOMPSON Timothy C; CAO Guang Wen; ZHANG Hong Wei; LIN Ji; HOU Jian Guo; XU Lei; CUI Xin Gang; XU Xing Xing; YU Yong Wei; HAN Xue; WANG Guo Min

    2014-01-01

    Objective To study the risk environmental and psycho-social factors associated to prostate cancer (PCa) in Chinese population. Methods 250 PCa patients and 500 controls were enrolled in this case-control study. Information was collected and logistic regression analysis was used to estimate the odds ratios (OR) and 95%confidence intervals (95% CI) for relationship between lifestyle, eating habits and psycho-social factors with PCa risk. Results Green vegetables and green tea were associated with a decreased risk of PCa (OR=0.39, 95%CI: 0.28-0.53; OR=0.59, 95% CI: 0.40-0.87, respectively). Family history of PCa (OR=7.16, 95% CI:2.01-25.49), history of prostate diseases (OR=2.28, 95%CI:1.53-3.41), alcohol consumption (OR=1.97, 95%CI:1.33-2.90), red meat consumption (OR=1.74, 95%CI:1.20-2.52), barbecued (OR=2.29, 95%CI:1.11-4.73) or fried (OR=2.35, 95%CI:1.24-4.43) foods were related with increased PCa risk. Negative psycho-social factors including occupational setbacks (OR=1.61, 95% CI: 1.00-2.59), marital separation (OR=1.94, 95%CI:1.29-2.91), self-contained suffering (OR=2.37, 95%CI:1.58-3.55), and high sensitivity to the personal comments (OR=1.73, 95%CI:1.18-2.54) were related to PCa. Conclusion Regular consumption of green vegetables and green tea may suggest protective effects on PCa. Alcohol consumption, red meat consumption and barbecued or fried foods were associated with PCa. Negative psycho-social factors may also play a role in the incidence of PCa in Chinese population.

  18. Relation of people-centered public health and person-centered healthcare management: a case study to reduce burn-out.

    Science.gov (United States)

    Stoyanov, Drozdstoj S; Cloninger, C Robert

    2012-01-01

    Healthcare management is one practical tool for mediation and implementation of public health into clinical healthcare outcomes and is taken in our case study as an exemplar arena to demonstrate the vital importance of the person-centered approach. Healthcare personnel are frequently at risk for the 'burn-out' syndrome. However, modern measures of burn-out recognize burn-out only at a late stage when it is fully developed. There are no available methods to assess the risk for vulnerability to burnout in healthcare systems. Our aim was therefore to design a complex person-centered model for detection of high risk for burn-out at an early stage, that has been termed 'flame-out'. We accept the observation that decreased personal performance is one crucial expression of burn-out. Low personal performance and negative emotions are strongly related to low self-directedness as measured by the Temperament and Character Inventory (TCI). At the same time, burn-out is characterized by decreased interest and positive emotions from work. Decreased positive emotion is directly related to low self-transcendence as measured by the TCI. Burn-out is also frequently associated with feelings of social alienation or inadequacy of support, which is in turn related to low TCI Cooperativeness. However, high Persistence and Harm Avoidance are predisposing traits for burn-out in healthcare professionals who are often overly perfectionistic and compulsive, predisposing them to anxiety, depression, suicide and burn-out. Hence, people at risk for future burn-out are often highly conscientious over-achievers with intense mixtures of positive and negative emotions. The high demand for perfection comes from both intrinsic characteristics and from features of the social milieu in their psychological climate. Letting go of the unfulfillable desire to be perfect by increasing self-transcendence allows acceptance of the imperfection of the human condition, thereby preventing burn-out and other

  19. Examples and Case Studies

    NARCIS (Netherlands)

    Asbach, C.; Aguerre, O.; Bressot, C.; Brouwer, D.H.; Gommel, U.; Gorbunov, B.; Bihan, O. le; Jensen, K.A.; Kaminski, H.; Keller, M.; Koponen, I.K.; Kuhlbusch, T.A.J.; Lecloux, A.; Morgeneyer, M.; Muir, R.; Shandilya, N.; Stahlmecke, B.; Todea, A.M.

    2014-01-01

    Release of nanomaterials may occur during any stage of the life-cycle and can eventually lead to exposure to humans, the environment or products. Due to the large number of combinations of release processes and nanomaterials, release scenarios can currently only be tested on a case-by-case basis. Th

  20. Final report on case studies

    DEFF Research Database (Denmark)

    Ljungberg, Daniel; McKelvey, Maureen; Lassen, Astrid Heidemann

    2012-01-01

    Case study as a research design means investigating a single or multiple instance(s) or setting(s) (i.e. a case) and its entire context to explain a phenomenon and its processes. This is achieved through detailed understanding, usually comprised of multiple sources of information. In this way, case...... studies attempt to provide as a complete an understanding of a (complex) phenomenon as possible. Within the AEGIS project, survey and case study research are complementary. They are complementary in the sense that the former can provide more generalizable evidence on a phenomenon in terms of cross......-sectional data, while the latter can provide more in-depth (qualitative) understanding on specific issues. In systematically examining the case studies, however, this report goes beyond a typical single case study. Here we provide a synthesis of 86 case studies. Multiple case studies, following similar focus...

  1. Natural Learning Case Study Archives

    Science.gov (United States)

    Lawler, Robert W.

    2015-01-01

    Natural Learning Case Study Archives (NLCSA) is a research facility for those interested in using case study analysis to deepen their understanding of common sense knowledge and natural learning (how the mind interacts with everyday experiences to develop common sense knowledge). The database comprises three case study corpora based on experiences…

  2. Dioxin: a case study.

    Science.gov (United States)

    Bond, G G

    1993-01-01

    The need to notify individuals of a possible health risk from their past exposure to potentially hazardous agents frequently extends beyond workers to include community groups. The issues to consider in community notification are frequently similar to those that are important for worker notification but may include some that are unique. This case study traces the evolution of one company's strategy for communicating with the public about possible dioxin contamination associated with its operations. Early communications tended to emphasize the technical aspects of the issues in the fashion of scientists talking to other scientists. This was interpreted by some to be symptomatic of an arrogant and uncaring attitude. Beginning in the early 1980s, the company's management recognized the need to reach out to a variety of audiences on multiple levels, and shifted to a more comprehensive communications strategy. A similar shift is now occurring throughout the chemical manufacturing industry as top managers realize that, if they expect to continue to operate, they must become more accountable and responsive to the public.

  3. Nutritional factors in relation to endometrial cancer: A report from a population-based case-control study in Shanghai, China

    OpenAIRE

    Xu, Wang-Hong; Dai, Qi; Xiang, Yong-Bing; Zhao, Gen-Ming; Ruan, Zhi-Xian; Cheng, Jia-Rong; Zheng, Wei; Shu, Xiao Ou

    2007-01-01

    We evaluated the role of dietary nutrients in the etiology of endometrial cancer in a population-based case-control study of 1,204 newly diagnosed endometrial cancer cases and 1,212 age frequency-matched controls. Information on usual dietary habits was collected during an in-person interview using a validated, quantitative food frequency questionnaire. Logistic regression analysis was conducted to evaluate the association of nutrients with endometrial cancer risk using an energy density meth...

  4. Splenectomy versus Partial Splenic Embolization for Massive Splenomegaly Secondary to Hepatitis B-Related Liver Cirrhosis: A Case-Control Study

    Directory of Open Access Journals (Sweden)

    Shoufei Jiao

    2016-01-01

    Full Text Available Background. Both splenectomy (SP and partial splenic embolization (PSE are used to treat massive splenomegaly (MSM secondary to hepatitis B-related liver cirrhosis (HB-LC. This retrospective case-control study was conducted to compare the effects of SP and PSE on these patients. Methods. From July 2004 to January 2012, patients with MSM secondary to HB-LC who underwent SP or PSE were 1 : 1 : 1 matched with similar nonsurgery patients, respectively. Intraoperative situation, hematological indices, liver function, HBV DNA level, HBeAg seroconversion rate, morbidity, and mortality at 6 months postoperatively were compared. Results. Operative time, estimated blood loss, blood transfusion rate, severe pain, postoperative stay, and portal vein thrombosis (PVT rate in the PSE group were significantly superior to the SP group, although SP and PSE were similar in liver function improvement, HBV suppression, morbidity, and mortality at 6 months postoperatively, and SP even improved WBC and PLT counts higher than PSE. Conclusion. Both SP and PSE are effective in improving liver function, increasing WBC and PLT counts, and suppressing replication of HBV for MSM secondary to HB-LC. Although postoperative improvement in WBC and PLT counts by SP can be higher than PSE, PSE is simple and minimally invasive and has a lower incidence of PVT.

  5. Multi-attribute decision making parametric optimization and modeling in hard turning using ceramic insert through grey relational analysis: A case study

    Directory of Open Access Journals (Sweden)

    Amlana Panda

    2016-09-01

    Full Text Available Machining of hardened work materials with appropriate levels of process parameters is still a burning issue in manufacturing sectors and challenging. It is because of pressing demand of surface quality which adversely affected by evolution of tool wear. Therefore the present investigation is undertaken to make a decision on parametric optimization of multi-responses such as flank wear and surface roughness during machining hardened AISI 52100 steel (55±1 steel using mixed ceramic insert under dry environment through grey relational analysis combined with Taguchi approach. Also predicted mathematical models of 1st and 2nd order have been developed for responses and checked for its accuracy. Second order mathematical model presented higher R2 value and represents best fit of the model and adequate compared to first order model. Model indicates good correlations between the experimental and predicted results. The proposed grey-based Taguchi methodology has been proved to be efficient for solving multi-attribute decision making problem as a case study in hard machining environment.

  6. A Case Study on the Professional Development of Elementary Teachers Related to Brain Research and the Strategies Used to Help Struggling Readers

    Science.gov (United States)

    Denton, Valerie R.

    2010-01-01

    This case study examined the impact of classroom interventions for struggling readers as changed/improved by teachers who participated in ongoing professional development on brain research studies. It investigated how teachers' knowledge of brain research impacted their instruction and the interventions they implemented in elementary classrooms.…

  7. Totally implantable catheter embolism: two related cases

    Directory of Open Access Journals (Sweden)

    Rodrigo Chaves Ribeiro

    Full Text Available CONTEXT AND OBJECTIVE: Long-term totally implantable catheters (e.g. Port-a-Cath® are frequently used for long-term venous access in children with cancer. The use of this type of catheter is associated with complications such as infection, extrusion, extravasation and thrombosis. Embolism of catheter fragments is a rare complication, but has potential for morbidity. The aim here was to report on two cases in which embolism of fragments of a long-term totally implantable catheter occurred. DESIGN AND SETTING: Case series study at Hospital do Servidor Público Estadual, São Paulo. METHODS: Retrospective review of catheter embolism in oncological pediatric patients with long-term totally implantable catheters. RESULTS: The first patient was a 3-year-old girl diagnosed with stage IV Wilms' tumor. Treatment was started with the introduction of a totally implantable catheter through the subclavian vein. At the time of removal, it was realized that the catheter had fractured inside the heart. An endovascular procedure was necessary to remove the fragment. The second case was a boy diagnosed with stage II Wilms' tumor at the age of two years. At the time of removal, it was noticed that the catheter had disconnected from the reservoir and an endovascular procedure was also necessary to remove the embolized catheter. CONCLUSION: Embolism of fragments of totally implantable catheters is a rare complication that needs to be recognized even in asymptomatic patients.

  8. Utilizing relative potency factors (RPF) and threshold of toxicological concern (TTC) concepts to assess hazard and human risk assessment profiles of environmental metabolites: a case study.

    Science.gov (United States)

    Terry, C; Rasoulpour, R J; Knowles, S; Billington, R

    2015-03-01

    There is currently no standard paradigm for hazard and human risk assessment of environmental metabolites for agrochemicals. Using an actual case study, solutions to challenges faced are described and used to propose a generic concept to address risk posed by metabolites to human safety. A novel approach - built on the foundation of predicted human exposures to metabolites in various compartments (such as food and water), the threshold of toxicological concern (TTC) and the concept of comparative toxicity - was developed for environmental metabolites of a new chemical, sulfoxaflor (X11422208). The ultimate aim was to address the human safety of the metabolites with the minimum number of in vivo studies, while at the same time, ensuring that human safety would be considered addressed on a global regulatory scale. The third component, comparative toxicity, was primarily designed to determine whether the metabolites had the same or similar toxicity profiles to their parent molecule, and also to one another. The ultimate goal was to establish whether the metabolites had the potential to cause key effects - such as cancer and developmental toxicity, based on mode-of-action (MoA) studies - and to develop a relative potency factor (RPF) compared to the parent molecule. Collectively, the work presented here describes the toxicology programme developed for sulfoxaflor and its metabolites, and how it might be used to address similar future challenges aimed at determining the relevance of the metabolites from a human hazard and risk perspective. Sulfoxaflor produced eight environmental metabolites at varying concentrations in various compartments - soil, water, crops and livestock. The MoA for the primary effects of the parent molecule were elucidated in detail and a series of in silico, in vitro, and/or in vivo experiments were conducted on the environmental metabolites to assess relative potency of their toxicity profiles when compared to the parent. The primary metabolite

  9. Case Studies in Middle Management Supervision

    Science.gov (United States)

    White, Lori S.

    2011-01-01

    This chapter presents a series of supervision-related case studies of situations that midlevel managers might face. Individuals enrolled in a midlevel management professional development course recommended the topics selected for this chapter. Drawing upon her experience teaching the course, the author selected four case studies that individuals…

  10. Intercultural Communicative Case Study

    Institute of Scientific and Technical Information of China (English)

    吴冬梅

    2009-01-01

    The essay is mainly about the author's comprehension of cultural differences and intercultural communication after reading the book Communication Between Cultures.In addition,the author also analyses three cases with the theories and approaches mentioned in Communication Between Cultures.

  11. Polymorphisms in NFKB1 and TLR4 and Interaction with Dietary and Life Style Factors in Relation to Colorectal Cancer in a Danish Prospective Case-Cohort Study

    DEFF Research Database (Denmark)

    Kopp, Tine Iskov; Andersen, Vibeke; Tjoøneland, Anne

    2015-01-01

    Maintenance of a balance between commensal bacteria and the mucosal immune system is crucial and intestinal dysbiosis may be a key event in the pathogenesis of colorectal cancer (CRC). The toll-like receptor 4 (TLR4) is an important pattern-recognition receptor that regulates inflammation...... and barrier function in the gut by a mechanism that involves activation of the nuclear factor-kappa B (NF-kappa B) transcription factor. Dietary and life style factors may impact these functions. We therefore used a Danish prospective case-cohort study of 1010 CRC cases and 1829 randomly selected participants...

  12. Cigarette smoking and lung cancer--relative risk estimates for the major histological types from a pooled analysis of case-control studies.

    Science.gov (United States)

    Pesch, Beate; Kendzia, Benjamin; Gustavsson, Per; Jöckel, Karl-Heinz; Johnen, Georg; Pohlabeln, Hermann; Olsson, Ann; Ahrens, Wolfgang; Gross, Isabelle Mercedes; Brüske, Irene; Wichmann, Heinz-Erich; Merletti, Franco; Richiardi, Lorenzo; Simonato, Lorenzo; Fortes, Cristina; Siemiatycki, Jack; Parent, Marie-Elise; Consonni, Dario; Landi, Maria Teresa; Caporaso, Neil; Zaridze, David; Cassidy, Adrian; Szeszenia-Dabrowska, Neonila; Rudnai, Peter; Lissowska, Jolanta; Stücker, Isabelle; Fabianova, Eleonora; Dumitru, Rodica Stanescu; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Rudin, Charles M; Brennan, Paul; Boffetta, Paolo; Straif, Kurt; Brüning, Thomas

    2012-09-01

    Lung cancer is mainly caused by smoking, but the quantitative relations between smoking and histologic subtypes of lung cancer remain inconclusive. By using one of the largest lung cancer datasets ever assembled, we explored the impact of smoking on risks of the major cell types of lung cancer. This pooled analysis included 13,169 cases and 16,010 controls from Europe and Canada. Studies with population controls comprised 66.5% of the subjects. Adenocarcinoma (AdCa) was the most prevalent subtype in never smokers and in women. Squamous cell carcinoma (SqCC) predominated in male smokers. Age-adjusted odds ratios (ORs) were estimated with logistic regression. ORs were elevated for all metrics of exposure to cigarette smoke and were higher for SqCC and small cell lung cancer (SCLC) than for AdCa. Current male smokers with an average daily dose of >30 cigarettes had ORs of 103.5 (95% confidence interval (CI): 74.8-143.2) for SqCC, 111.3 (95% CI: 69.8-177.5) for SCLC and 21.9 (95% CI: 16.6-29.0) for AdCa. In women, the corresponding ORs were 62.7 (95% CI: 31.5-124.6), 108.6 (95% CI: 50.7-232.8) and 16.8 (95% CI: 9.2-30.6), respectively. Although ORs started to decline soon after quitting, they did not fully return to the baseline risk of never smokers even 35 years after cessation. The major result that smoking exerted a steeper risk gradient on SqCC and SCLC than on AdCa is in line with previous population data and biological understanding of lung cancer development.

  13. Systematic investigation of gridding-related scaling effects on annual statistics of daily temperature and precipitation maxima: A case study for south-east Australia

    Directory of Open Access Journals (Sweden)

    Francia B. Avila

    2015-09-01

    Full Text Available Using daily station observations over the period 1951–2013 in a region of south-east Australia, we systematically compare how the horizontal resolution, interpolation method and order of operation in generating gridded data sets affect estimates of annual extreme indices of temperature and precipitation maxima (hottest and wettest days. Three interpolation methods (natural neighbors, cubic spline and angular distance weighting are used to calculate grids at five different horizontal gridded resolutions ranging from 0.25° to 2.5°. In each case the order of operation in which the grid values of the hottest and wettest day are calculated is varied: either they are estimated from daily grids or from station points and then gridded. We find that the grid resolution-despite showing more regional detail at high resolution – has relatively limited effect when considering regional averages. However, the interpolation method and the order of operation can substantially influence the actual gridded values. And while the difference due to the order of operation is not substantial when using natural neighbor and cubic spline interpolation, it is particularly apparent for indices calculated from daily gridded estimates using the angular distance weighting method. As expected given the high spatial variability of precipitation fields, precipitation extremes are most sensitive to method, but temperature extremes also exhibit substantial differences. For the annual maximum values averaged over the study area, the differences may be up to 2.8 °C for temperature and 60 mm (about a factor 2 for precipitation. Differences are seen most prominently in return period estimates where a 1 in 100 year return value calculated using the angular distance weighting daily gridded method is equivalent to about a 1 in 5 year return value in most of the other methods. Despite substantial differences in the actual values of gridded extremes, analyses suggest that the

  14. Emotion, Engagement, and Case Studies

    Science.gov (United States)

    Herreid, Clyde Freeman; Terry, David R.; Lemons, Paula; Armstrong, Norris; Brickman, Peggy; Ribbens, Eric

    2014-01-01

    Three college faculty taught large general biology classes using case studies and personal response systems (clickers). Each instructor taught the same eight cases in two different sections, except the questions within the cases differed. In one section the questions were lower order (LO) factual inquiries, and in the other they were largely…

  15. A case study comparing the relative benefit of optimizing beam weights, wedge angles, beam orientations and tomotherapy in stereotactic radiotherapy of the brain

    Science.gov (United States)

    Oldham, M.; Khoo, V. S.; Rowbottom, C. G.; Bedford, J. L.; Webb, S.

    1998-08-01

    A treatment-planning case study has been performed on a patient with a medium-sized, convex brain tumour. The study involved the application of advanced treatment-plan optimization techniques to improve on the dose distribution of the `standard plan' used to treat the patient. The standard plan was created according to conventional protocol at the Royal Marsden NHS Trust, and consisted of a three-field (one open and two wedged) non-coplanar arrangement, with field shaping to the beam's-eye view of the planning target volume (PTV). Three optimized treatment plans were created corresponding to (i) the optimization of the beam weights and wedge angles of the standard plan, (ii) the optimization of the beam orientations, beam weights and wedge angles of the standard plan, and (iii) a full fluence tomotherapy optimization of 1 cm wide (at isocentre), 43/8/010/img8.gif" ALIGN="MIDDLE"/> arcs. (i) and (ii) were created on the VOXELPLAN research 3D treatment-planning system, using in-house developed optimization algorithms, and (iii) was created on the PEACOCK tomotherapy planning system. The downhill-simplex optimization algorithm is used, in conjuction with `threshold-dose' cost-function terms enabling the algorithm to optimize specific regions of the dose-volume histogram (DVH) curve. The `beam-cost plot' tool is presented as a visual aid to the selection of beneficial beam directions. The methods and pitfalls in the transfer of plans and patient data between the two planning systems are discussed. Each optimization approach was evaluated, relative to the standard plan, on the basis of DVH and dose statistics in the PTV and organs at risk (OARs). All three optimization approaches were able to improve on the dose distribution of the standard plan. The magnitude of the improvement was greater for the optimized beam-orientation and tomotherapy plans (up to 15% and 30% for the maximum and mean OAR doses). A smaller improvement was observed in the beam-weight and wedge

  16. Case Study: Case Studies and the Flipped Classroom

    Science.gov (United States)

    Herreid, Clyde Freeman; Schiller, Nancy A.

    2013-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's issue discusses the positive and negative aspects of the "flipped classroom." In the flipped classroom model, what is normally done in class and what is normally done as…

  17. Building theories from case study research: the progressive case study

    NARCIS (Netherlands)

    Steenhuis, Harm-Jan; Bruijn, de Erik J.

    2006-01-01

    Meredith (1998) argues for more case and field research studies in the field of operations management. Based on a literature review, we discuss several existing approaches to case studies and their characteristics. These approaches include; the Grounded Theory approach which proposes no prior litera

  18. Theory Testing Using Case Studies

    DEFF Research Database (Denmark)

    Møller, Ann-Kristina Løkke; Dissing Sørensen, Pernille

    2014-01-01

    testing using case studies, including the associated research goal, analysis, and generalisability. We argue that research designs for theory testing using case studies differ from theorybuilding case study research designs because different research projects serve different purposes and follow different......The appropriateness of case studies as a tool for theory testing is still a controversial issue, and discussions about the weaknesses of such research designs have previously taken precedence over those about its strengths. The purpose of the paper is to examine and revive the approach of theory...... research paths....

  19. Insulin-like growth factor-related components and the risk of liver cancer in a nested case-control study.

    Science.gov (United States)

    Adachi, Yasushi; Nojima, Masanori; Mori, Mitsuru; Matsunaga, Yasutaka; Akutsu, Noriyuki; Sasaki, Shigeru; Endo, Takao; Kurozawa, Youichi; Wakai, Kenji; Tamakoshi, Akiko

    2016-11-01

    Insulin-like growth factor-1 (IGF1) is a potent mitogen. IGF-binding protein-3 (IGFBP3) binds and inhibits IGF1. High circulating IGF1 levels and low IGFBP3 levels are associated with increased risk of several cancers. We examined relationships between serum levels of these factors and hepatoma risk in a case-control study nested in a prospective cohort study (the Japan Collaborative Cohort Study (JACC Study)). A baseline survey was conducted from 1988 to 1990, and 39,242 subjects donated blood samples. Participants diagnosed with hepatoma by 1997 were considered cases for nested case-control studies. Ninety-one cases and 263 sex- and age-matched controls were analyzed. A conditional logistic model was used to estimate odds ratios (ORs) for the incidence of hepatoma associated with serum IGF1 and IGFBP3 levels. Neither IGF1 nor the molar ratio of IGF1/IGFBP3 was correlated with hepatoma risk. After adjustment for hepatitis viral infection, body mass index, smoking, and alcohol intake, a higher molar difference of (IGFBP3 - IGF1) was associated with a decreased hepatoma risk more than IGFBP3 alone (p for trend <0.001 and = 0.003, respectively). People in the highest quartile had a lower risk (OR = 0.098; 95 % confidence interval = 0.026-0.368). In subgroup analyses of males and females, the molar difference was associated with a decreased hepatoma risk (p for trend <0.05). In non-elderly individuals, the difference was inversely correlated with the incidence of hepatoma (p for trend <0.01). The molar difference of (IGFBP3 - IGF1) may be inversely associated with the incidence of hepatoma.

  20. EU External Relations Law: Text, Cases and Materials

    DEFF Research Database (Denmark)

    Butler, Graham

    2014-01-01

    EU External Relations Law: Text, Cases and Materials, Bart Van Vooren and Ramses A. Wessel, Cambridge University Press, UK, 2014.......EU External Relations Law: Text, Cases and Materials, Bart Van Vooren and Ramses A. Wessel, Cambridge University Press, UK, 2014....

  1. The Relation between Candidate Teachers' Moral Maturity Levels and Their Individual Innovativeness Characteristics: A Case Study of Harran University Education Faculty

    Science.gov (United States)

    Adiguzel, Abdullah

    2012-01-01

    The purpose of the present study is to determine the relation between the moral maturity levels of candidate teachers and their individual innovativeness characteristics. The population of the study consisted of undergraduate students who were registered at Harran University Faculty of Education in the 2011 to 2012 academic year. Data were…

  2. Theory testing using case studies

    DEFF Research Database (Denmark)

    Dissing Sørensen, Pernille; Løkke Nielsen, Ann-Kristina

    Case studies may have different research goals. One such goal is the testing of small-scale and middle-range theories. Theory testing refers to the critical examination, observation, and evaluation of the 'why' and 'how' of a specified phenomenon in a particular setting. In this paper, we focus...... on the strengths of theory-testing case studies. We specify research paths associated with theory testing in case studies and present a coherent argument for the logic of theoretical development and refinement using case studies. We emphasize different uses of rival explanations and their implications for research...... design. Finally, we discuss the epistemological logic, i.e., the value to larger research programmes, of such studies and, following Lakatos, conclude that the value of theory-testing case studies lies beyond naïve falsification and in their contribution to developing research programmes in a progressive...

  3. Pain-related somatosensory evoked potentials and functional brain magnetic resonance in the evaluation of neurologic recovery after cardiac arrest: a case study of three patients.

    Science.gov (United States)

    Zanatta, Paolo; Messerotti Benvenuti, Simone; Baldanzi, Fabrizio; Bendini, Matteo; Saccavini, Marsilio; Tamari, Wadih; Palomba, Daniela; Bosco, Enrico

    2012-03-31

    This case series investigates whether painful electrical stimulation increases the early prognostic value of both somatosensory-evoked potentials and functional magnetic resonance imaging in comatose patients after cardiac arrest. Three single cases with hypoxic-ischemic encephalopathy were considered. A neurophysiological evaluation with an electroencephalogram and somatosensory-evoked potentials during increased electrical stimulation in both median nerves was performed within five days of cardiac arrest. Each patient also underwent a functional magnetic resonance imaging evaluation with the same neurophysiological protocol one month after cardiac arrest. One patient, who completely recovered, showed a middle latency component at a high intensity of stimulation and the activation of all brain areas involved in cerebral pain processing. One patient in a minimally conscious state only showed the cortical somatosensory response and the activation of the primary somatosensory cortex. The last patient, who was in a vegetative state, did not show primary somatosensory evoked potentials; only the activation of subcortical brain areas occurred. These preliminary findings suggest that the pain-related somatosensory evoked potentials performed to increase the prognosis of comatose patients after cardiac arrest are associated with regional brain activity showed by functional magnetic resonance imaging during median nerves electrical stimulation. More importantly, this cases report also suggests that somatosensory evoked potentials and functional magnetic resonance imaging during painful electrical stimulation may be sensitive and complementary methods to predict the neurological outcome in the acute phase of coma. Thus, pain-related somatosensory-evoked potentials may be a reliable and a cost-effective tool for planning the early diagnostic evaluation of comatose patients.

  4. Instructional Computing: Ten Case Studies.

    Science.gov (United States)

    Hargan, Carol; Hunter, Beverly

    These case studies are written for educational institutions that wish to plan, extend, or improve their use of computers for learning and teaching. Each case study includes a brief description of each of the following: profile of the institution, history of the development of instructional computing, organization and management, student access to…

  5. Three Community College Case Studies

    Science.gov (United States)

    Wojtysiak, Joseph; Sutton, William J., II; Wright, Tommy; Brantley, Linda

    2011-01-01

    This article presents three case studies that focus on specific projects that are underway or have been completed. In the first case study, Joseph Wojtysiak and William J. Sutton, II discuss the Green Center of Central Pennsylvania, which is designed to serve as the state's preeminent source for education, training and public information about…

  6. Related Factors of Elective Cesarean Section: A Case-Control Study%选择性剖宫产的相关因素研究

    Institute of Scientific and Technical Information of China (English)

    李艳芳; 李越游; 林黛

    2010-01-01

    目的 总结广州市番禺区妇幼保健院在过去十年剖宫产率的变化和趋势,分析2009年该院病人相关的和医师相关的因素与选择性剖宫产的关系.方法 这是一个病例对照研究,病例是应病人自己要求或手术指征不明确的选择性剖宫产分娩的妇女,对照则是有明确手术指征的剖宫产分娩妇女.PS power软件用于计算样本量,通过分层随机抽样的方法,在4176个2009年住院分娩的病历中随机抽取709个总样本(其中病例数是348个,对照是361个).通过病历回顾,收集所有与病人相关的及与医生相关的非医学因素.采用SPSS 16.0软件进行数据处理,运用卡方检验和Logistic回归方程进行检测.结果 该院的剖宫产率从2000年的41.8%到2009年的59.9%,总体呈一个线性的提高.选择性剖宫产更多发生在正常上班时间,产检次数越多的病人越容易在无手术指征的情况下选择剖宫产.结论 在本研究人群中,产科医师的偏好影响病人对剖宫产的选择,医师便利及害怕医疗纠纷可能是医师选择治疗方式的主要驱动因素.因此,选择性剖宫产率的控制措施应更侧重于改变医师的行为模式,而不仅仅是患者教育.%Objective To summarize the trend of CSR at a district public hospital in Guangzhou in the past decade and to identify patient and physician-related factors for elective cesarean section in 2009.Methods This was a case-control study. All available non-medical risk factors were collected from inpatient medical records. PS power software was used to calculate sample size. Cases were women who underwent Cesarean delivery at maternal recquest or for unclear obstetric indication and controls were women who underwent Cesarean delivery with one or more medical indications. A total sample size of 709 (348 cases and 361 controls) was obtained via stratified random sampling from 4176 in-patient delivery records in 2009.Risk factors for CS were examined

  7. Different aspects of oral health, dental treatment needs and oral health-related quality of life In Lithuanian patients with haemophilia – a case control study

    OpenAIRE

    Žaliūnienė, Rūta

    2016-01-01

    Haemophilia is a life-threatening inherited bleeding disorder. A rather common complication occurring in patients with haemophilia is excessive and spontaneous bleeding after dental procedures particularly after tooth extraction. There were no previous Lithuanian studies evaluating different aspects of oral health and its related determinants among haemophilia patients. The present study estimated caries experience, dental treatment experience, unmet dental treatment needs, presence of fu...

  8. Roundabouts Canada case study

    Energy Technology Data Exchange (ETDEWEB)

    Jamieson, M. [Ryerson Polytechnic Univ., Toronto, ON (Canada); Lenters, M. [Roundabouts Canada, Whitby, ON (Canada)

    2002-07-01

    A modern roundabout was constructed in the community of Ancaster, Ontario in response to growing complaints regarding speeding along the major roadway, and queuing on the minor roadway. The roundabout opened on October 25, 2002. The before and after speeds at the roundabout are being studied, and the fastest path characteristics are assessed in an effort to determine whether the predicted fastest path data correlates with the in-service operating speeds. The speed at R1, R2 and R3 locations on the east west, and north south approaches are measured. tabs., figs.

  9. The Perceptions of the Automotive Supply Industry Related to Information Technology Utilization and Creating Barriers to Competitive Market Entry: A Case Study of the Implications for Strategic Planning

    Science.gov (United States)

    Cargal, Joseph L.

    2010-01-01

    The purpose of this study was to examine information technology/systems strategy related factors in the automotive supply industry based on responses to the Strategic Planning and Business Performance Survey provided to automotive suppliers. This population produces supplies to the automotive industry with products valued at hundreds of billions…

  10. Case Studies in Science Ethics

    Science.gov (United States)

    Williams, Karen

    2010-03-01

    Everyone in science should have ethics education training. I have seen graduate students taken advantage of by their mentors. Many of us have seen misconduct...but what should we do about it? Young scientists are often unaware of the rules in science and make mistakes because of their ignorance of the rules in that particular field of study. Then there are an increasing number of cases in the news of overt cases of misrepresentation in science. All are welcome to attend this discussion of case studies. A case study on topics such as: how to treat data properly, how our values in science affect our work, who gets authorship on scientific papers, who is first author on a paper, what you should do if you uncover misconduct or plagiarism in your university, and we will discuss the scientist's role in society. This will be a painless, non-confrontational small group, then large group discussion of each case

  11. Periconceptional folic acid associated with an increased risk of oral clefts relative to non-folate related malformations in the Northern Netherlands : a population based case-control study

    NARCIS (Netherlands)

    Rozendaal, Anna M; van Essen, Anthonie J; te Meerman, Gerard J; Bakker, Marian K; van der Biezen, Jan J; Goorhuis-Brouwer, Sieneke M; Vermeij-Keers, Christl; de Walle, Hermien E K; te Meerman, Gerhardus

    2013-01-01

    Periconceptional folic acid has been associated with a reduced risk of neural tube defects, but findings on its effect in oral clefts are largely inconclusive. This case-control study assesses the effects of periconceptional folic acid on cleft risk, using complementary data from the Dutch Oral Clef

  12. Hydrogeologic Case Studies (Seattle, WA)

    Science.gov (United States)

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  13. Nasopharyngeal Case-Control Study

    Science.gov (United States)

    A case-control study conducted in Taiwan between 1991-1994 among approximately 1,000 individuals to examine the role of viral, environmental, and genetic factors associated with the development of nasopharyngeal carcinoma

  14. Case Studies in Strategic Planning

    Science.gov (United States)

    1990-03-06

    Contains developed case studies in strategic planning on The Navy General Board, Joint Service War Planning 1919 to 1941, Navy Strategic Planning , NASA...in Strategic Planning NPS-56-88-031-PR of September 1988. Strategic planning , Strategic Management.

  15. Case Study: del Amo Bioventing

    Science.gov (United States)

    The attached presentation discusses the fundamentals of bioventing in the vadose zone. The basics of bioventing are presented. The experience to date with the del Amo Superfund Site is presented as a case study.

  16. Theoretical pluralism in psychoanalytic case studies.

    Science.gov (United States)

    Willemsen, Jochem; Cornelis, Shana; Geerardyn, Filip M; Desmet, Mattias; Meganck, Reitske; Inslegers, Ruth; Cauwe, Joachim M B D

    2015-01-01

    The aim of this study is to provide an overview of the scientific activity of different psychoanalytic schools of thought in terms of the content and production of case studies published on ISI Web of Knowledge. Between March 2013 and November 2013, we contacted all case study authors included in the online archive of psychoanalytic and psychodynamic case studies (www.singlecasearchive.com) to inquire about their psychoanalytic orientation during their work with the patient. The response rate for this study was 45%. It appears that the two oldest psychoanalytic schools, Object-relations psychoanalysis and Ego psychology or "Classical psychoanalysis" dominate the literature of published case studies. However, most authors stated that they feel attached to two or more psychoanalytic schools of thought. This confirms that the theoretical pluralism in psychoanalysis stretches to the field of single case studies. The single case studies of each psychoanalytic school are described separately in terms of methodology, patient, therapist, or treatment features. We conclude that published case studies features are fairly similar across different psychoanalytic schools. The results of this study are not representative of all psychoanalytic schools, as some do not publish their work in ISI ranked journals.

  17. Clinical features and neuroimaging (CT and MRI) findings in presumed Zika virus related congenital infection and microcephaly: retrospective case series study

    Science.gov (United States)

    van der Linden, Vanessa; Brainer-Lima, Alessandra Mertens; Coeli, Regina Ramos; Rocha, Maria Angela; Sobral da Silva, Paula; Durce Costa Gomes de Carvalho, Maria; van der Linden, Ana; Cesario de Holanda, Arthur; Valenca, Marcelo Moraes

    2016-01-01

    Objective To report radiological findings observed in computed tomography (CT) and magnetic resonance imaging (MRI) scans of the first cases of congenital infection and microcephaly presumably associated with the Zika virus in the current Brazilian epidemic. Design Retrospective study with a case series. Setting Association for Assistance of Disabled Children (AACD), Pernambuco state, Brazil. Participants 23 children with a diagnosis of congenital infection presumably associated with the Zika virus during the Brazilian microcephaly epidemic. Main outcome measures Types of abnormalities and the radiological pattern of lesions identified on CT and MRI brain scans. Results Six of the 23 children tested positive for IgM antibodies to Zika virus in cerebrospinal fluid. The other 17 children met the protocol criteria for congenital infection presumably associated with the Zika virus, even without being tested for IgM antibodies to the virus—the test was not yet available on a routine basis. Of the 23 children, 15 underwent CT, seven underwent both CT and MRI, and one underwent MRI. Of the 22 children who underwent CT, all had calcifications in the junction between cortical and subcortical white matter, 21 (95%) had malformations of cortical development, 20 (91%) had a decreased brain volume, 19 (86%) had ventriculomegaly, and 11 (50%) had hypoplasia of the cerebellum or brainstem. Of the eight children who underwent MRI, all had calcifications in the junction between cortical and subcortical white matter, malformations of cortical development occurring predominantly in the frontal lobes, and ventriculomegaly. Seven of the eight (88%) children had enlarged cisterna magna, seven (88%) delayed myelination, and six each (75%) a moderate to severe decrease in brain volume, simplified gyral pattern, and abnormalities of the corpus callosum (38% hypogenesis and 38% hypoplasia). Malformations were symmetrical in 75% of the cases. Conclusion Severe cerebral damage was

  18. LANDFORM MORPHOLOGIC RELATIONS BETWEEN INTER-GULLIED AND GULLIED LAND AREAS--A CASE STUDY OF THE WANGJIAGOU WATERSHED IN THE WEST OF SHANXI PROVINCE

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Previous studies on erosional relations between inter-gullied and gullied lands have mainly concentrated on exploration of water and sediment relations, with few quantitative studies of evolution relations between inter-gullied land and gullied landform erosion in small catchments. This paper, using information from a 1:5000 digital orthophotomap (DOM), digital elevation model(DEM), and topographic map of the same period and of the same scale, quantitatively analyzes the impact and interactions of inter-gullied and gullied land geomorphologic characteristics on the dissected extent of a catchment using orthogonal polynomial regression analysis. Results indicate that gullies play a leading role in the catchment morphologic evolution and extent of cracked ground surface. When inter-gullied land areas are the same, a 0. 1 km2 gullied land area has the maximum effect on the erosive evolution intensity of the catchment cracked degree. The smaller the catchment area is, the greater the extent of cracked ground surface and gully intensity would be. The geomorphologic evolution mechanism of gullied catchments can be explained as a function of geomorphologic indicators of inter-gullied and gullied land characteristics.

  19. Assessment of Industry-Induced Urban Human Health Risks Related to Benzo[a]pyrenebased on a Multimedia Fugacity Model: Case Study of Nanjing, China.

    Science.gov (United States)

    Xu, Linyu; Song, Huimin; Wang, Yan; Yin, Hao

    2015-05-29

    Large amounts of organic pollutants emitted from industries have accumulated and caused serious human health risks, especially in urban areas with rapid industrialization. This paper focused on the carcinogen benzo[a]pyrene (BaP) from industrial effluent and gaseous emissions, and established a multi-pathway exposure model based on a Level IV multimedia fugacity model to analyze the human health risks in a city that has undergone rapid industrialization. In this study, GIS tools combined with land-use data was introduced to analyze smaller spatial scales so as to enhance the spatial resolution of the results. An uncertainty analysis using a Monte Carlo simulation was also conducted to illustrate the rationale of the probabilistic assessment mode rather than deterministic assessment. Finally, the results of the case study in Nanjing, China indicated the annual average human cancer risk induced by local industrial emissions during 2002-2008 (lowest at 1.99x10(-6) in 2008 and highest at 3.34x10(-6) in 2004), which was lower than the USEPA prescriptive level (1x10(-6)-1x10(-4)) but cannot be neglected in the long term. The study results could not only instruct the BaP health risk management but also help future health risk prediction and control.

  20. Assessment of Industry-Induced Urban Human Health Risks Related to Benzo[a]pyrene based on a Multimedia Fugacity Model: Case Study of Nanjing, China

    Directory of Open Access Journals (Sweden)

    Linyu Xu

    2015-05-01

    Full Text Available Large amounts of organic pollutants emitted from industries have accumulated and caused serious human health risks, especially in urban areas with rapid industrialization. This paper focused on the carcinogen benzo[a]pyrene (BaP from industrial effluent and gaseous emissions, and established a multi-pathway exposure model based on a Level IV multimedia fugacity model to analyze the human health risks in a city that has undergone rapid industrialization. In this study, GIS tools combined with land-use data was introduced to analyze smaller spatial scales so as to enhance the spatial resolution of the results. An uncertainty analysis using a Monte Carlo simulation was also conducted to illustrate the rationale of the probabilistic assessment mode rather than deterministic assessment. Finally, the results of the case study in Nanjing, China indicated the annual average human cancer risk induced by local industrial emissions during 2002–2008 (lowest at 1.99´10–6 in 2008 and highest at 3.34´10–6 in 2004, which was lower than the USEPA prescriptive level (1´10–6–1´10–4 but cannot be neglected in the long term. The study results could not only instruct the BaP health risk management but also help future health risk prediction and control.

  1. Cannabis-dependence risk relates to synergism between neuroticism and proenkephalin SNPs associated with amygdala gene expression: case-control study.

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    Didier Jutras-Aswad

    Full Text Available Many young people experiment with cannabis, yet only a subgroup progress to dependence suggesting individual differences that could relate to factors such as genetics and behavioral traits. Dopamine receptor D2 (DRD2 and proenkephalin (PENK genes have been implicated in animal studies with cannabis exposure. Whether polymorphisms of these genes are associated with cannabis dependence and related behavioral traits is unknown.Healthy young adults (18-27 years with cannabis dependence and without a dependence diagnosis were studied (N = 50/group in relation to a priori-determined single nucleotide polymorphisms (SNPs of the DRD2 and PENK genes. Negative affect, Impulsive Risk Taking and Neuroticism-Anxiety temperamental traits, positive and negative reward-learning performance and stop-signal reaction times were examined. The findings replicated the known association between the rs6277 DRD2 SNP and decisions associated with negative reinforcement outcomes. Moreover, PENK variants (rs2576573 and rs2609997 significantly related to Neuroticism and cannabis dependence. Cigarette smoking is common in cannabis users, but it was not associated to PENK SNPs as also validated in another cohort (N = 247 smokers, N = 312 non-smokers. Neuroticism mediated (15.3%-19.5% the genetic risk to cannabis dependence and interacted with risk SNPs, resulting in a 9-fold increase risk for cannabis dependence. Molecular characterization of the postmortem human brain in a different population revealed an association between PENK SNPs and PENK mRNA expression in the central amygdala nucleus emphasizing the functional relevance of the SNPs in a brain region strongly linked to negative affect.Overall, the findings suggest an important role for Neuroticism as an endophenotype linking PENK polymorphisms to cannabis-dependence vulnerability synergistically amplifying the apparent genetic risk.

  2. Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits

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    Almind Katrine

    2008-12-01

    Full Text Available Abstract Background Several studies in multiple ethnicities have reported linkage to type 2 diabetes on chromosome 1q21-25. Both PKLR encoding the liver pyruvate kinase and NOS1AP encoding the nitric oxide synthase 1 (neuronal adaptor protein (CAPON are positioned within this chromosomal region and are thus positional candidates for the observed linkage peak. The C-allele of PKLR rs3020781 and the T-allele of NOS1AP rs7538490 are reported to strongly associate with type 2 diabetes in various European-descent populations comprising a total of 2,198 individuals with a combined odds ratio (OR of 1.33 [1.16–1.54] and 1.53 [1.28–1.81], respectively. Our aim was to validate these findings by investigating the impact of the two variants on type 2 diabetes and related quantitative metabolic phenotypes in a large study sample of Danes. Further, we intended to expand the analyses by examining the effect of the variants in relation to overweight and obesity. Methods PKLR rs3020781 and NOS1AP rs7538490 were genotyped, using TaqMan allelic discrimination, in a combined study sample comprising a total of 16,801 and 16,913 individuals, respectively. The participants were ascertained from four different study groups; the population-based Inter99 cohort (nPKLR = 5,962, nNOS1AP = 6,008, a type 2 diabetic patient group (nPKLR = 1,873, nNOS1AP = 1,874 from Steno Diabetes Center, a population-based study sample (nPKLR = 599, nNOS1AP = 596 from Steno Diabetes Center and the ADDITION Denmark screening study cohort (nPKLR = 8,367, nNOS1AP = 8,435. Results In case-control studies we evaluated the potential association between rs3020781 and rs7538490 and type 2 diabetes and obesity. No significant associations were observed for type 2 diabetes (rs3020781: pAF = 0.49, OR = 1.02 [0.96–1.10]; rs7538490: pAF = 0.84, OR = 0.99 [0.93–1.06]. Neither did we show association with overweight or obesity. Additionally, the PKLR and the NOS1AP genotypes were demonstrated not

  3. Case Study: A Strategic Research Methodology

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    Khairul B.M. Noor

    2008-01-01

    Full Text Available This research reviews the literature on case study as a strategic qualitative research methodology. Although case studies have been criticised by some authors as lacking scientific rigour and do not address generalizability, this research, however, reiterated its appropriateness when dealing with a process or a complex real-life activities in great-depth. Case study has been commonly used in social science fields like sociology, industrial relations and anthropology eventhough generally was considered an underutilized strategy. Hence, this research explained the general concept of a case study, strengths and weaknesses of using this method knowing that theoretically case is exciting and data rich. Based on a study of four organizations and the researcher’s own experience, this article described matters on how case study was undertaken, gaining excess to those organizations and the systematic process of data collection and triangulation (multiple techniques. It was noted that combining multiple techniques for elicitng data in case study research actually strengthens and confirmed results.

  4. High glycemic load diet, milk and ice cream consumption are related to acne vulgaris in Malaysian young adults: a case control study

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    Ismail Noor

    2012-08-01

    Full Text Available Abstract Background The role of dietary factors in the pathophysiology of acne vulgaris is highly controversial. Hence, the aim of this study was to determine the association between dietary factors and acne vulgaris among Malaysian young adults. Methods A case–control study was conducted among 44 acne vulgaris patients and 44 controls aged 18 to 30 years from October 2010 to January 2011. Comprehensive acne severity scale (CASS was used to determine acne severity. A questionnaire comprising items enquiring into the respondent’s family history and dietary patterns was distributed. Subjects were asked to record their food intake on two weekdays and one day on a weekend in a three day food diary. Anthropometric measurements including body weight, height and body fat percentage were taken. Acne severity was assessed by a dermatologist. Results Cases had a significantly higher dietary glycemic load (175 ± 35 compared to controls (122 ± 28 (p  0.05. Conclusions Glycemic load diet and frequencies of milk and ice cream intake were positively associated with acne vulgaris.

  5. Social Determinants of Chronic Prostatitis/Chronic Pelvic Pain Syndrome Related Lifestyle and Behaviors among Urban Men in China: A Case-Control Study

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    Yan Wang

    2016-01-01

    Full Text Available Purpose. In order to find key risk factors of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS among urban men in China, an age-matched case-control study was performed from September 2012 to May 2013 in Yichang, Hubei Province, China. Methodology. A total of 279 patients and 558 controls were recruited in this study. Data were collected by a self-administered questionnaire, including demographics, diet and lifestyle, psychological status, and a physical exam. Conditional logistic regression model was used to analyze collected data. Results. Chemical factors exposure, night shift, severity of mood, and poor self-health cognition were entered into the regression model, and result displayed that these four factors had odds ratios of 1.929 (95% CI, 1.321–2.819, 1.456 (95% CI, 1.087–1.949, 1.619 (95% CI, 1.280–2.046, and 1.304 (95% CI, 1.094–1.555, respectively, which suggested that these four factors could significantly affect CP/CPPS. Conclusion. These results suggest that many factors affect CP/CPPS, including biological, social, and psychological factors.

  6. Circulating High-Molecular-Weight (HMW) Adiponectin Level Is Related with Breast Cancer Risk Better than Total Adiponectin: A Case-Control Study.

    Science.gov (United States)

    Guo, Ming-ming; Duan, Xue-ning; Cui, Shu-de; Tian, Fu-guo; Cao, Xu-chen; Geng, Cui-zhi; Fan, Zhi-min; Wang, Xiang; Wang, Shu; Jiang, Hong-chuan; Zhang, Jian-guo; Jin, Feng; Tang, Jin-hai; Liang, Hong; Yang, Zhen-lin; Wang, Hai-bo; Wang, Qi-tang; Li, Guo-lou; Li, Liang; Zhu, Shi-guang; Zuo, Wen-shu; Liu, Li-yuan; Wang, Lu; Ma, Dan-dan; Liu, Shu-chen; Xiang, Yu-juan; Liu, Lu; Ye, Chun-miao; Zhou, Wen-zhong; Wang, Fei; Yu, Li-xiang; Ma, Zhong-bing; Yu, Zhi-gang

    2015-01-01

    The level of total adiponectin, a mixture of different adiponectin forms, has been reported associated with breast cancer risk with inconsistent results. Whether the different forms play different roles in breast cancer risk prediction is unclear. To examine this, we measured total and high molecular weight (HMW) adiponectin in a case-control study (1167 sets). Higher circulating HMW adiponectin was negatively associated with breast cancer risk after adjusting for menopausal status and family history of breast cancer (P=0.024). We analyzed the relationship between adiponectin and breast cancer risk in 6 subgroups. Higher circulating HMW adiponectin was also negatively associated with breast cancer risk (P=0.020, 0.014, 0.035) in the subgroups of postmenopausal women, negative family history of breast cancer, BMI>=24.0. Total adiponectin was positively associated with breast cancer (P=0.028) in the subgroup of BMIbreast cancer risk (P=0.034, 0.0116). This study showed different forms of circulating adiponectin levels might play different roles in breast cancer risk. A higher circulating HMW adiponectin is associated with a decreased breast cancer risk, especially in postmenopausal, without family history of breast cancer or BMI>=24.0 subgroups, whereas higher circulating HMW adiponectin levels is a risk factor in women with a family history of breast cancer. Further investigation of different forms of adiponectin on breast cancer risk is needed.

  7. The relative influence of the community and the health system on work performance: a case study of community health workers in Colombia.

    Science.gov (United States)

    Robinson, S A; Larsen, D E

    1990-01-01

    A central component of the primary health care approach in developing countries has been the development and utilization of community-based health workers (CHWs) within the national health system. While the use of these front line workers has the potential to positively influence health behavior and health status in rural communities, there continues to be challenges to effective implementation of CHW programs. Reports of high turnover rates, absenteeism, poor quality of work, and low morale among CHWs have often been associated with weak organizational and managerial capacity of government health systems. However, no systematic research has examined the contribution of work-related factors to CHW job performance. The research reported in this paper examines the relative influence of reward and feedback factors associated with the community compared to those associated with the health system on the performance of CHWs. The data are drawn from a broader study of health promoters (CHWs) conducted in two departments (provinces) in Colombia in 1986. The research was based on a theoretical model of worker performance that focuses on job related sources of rewards and feedback. A survey research design was employed to obtain information from a random sample of rural health promoters (N = 179) and their auxiliary nurse supervisors about CHW performance and contributing factors. The findings indicate that feedback and rewards from the community have a greater influence on work performance (defined as degree of perceived goal attainment on job tasks) than do those stemming from the health system.(ABSTRACT TRUNCATED AT 250 WORDS)

  8. Controlling the didactic relation: a case in process engineering education

    Science.gov (United States)

    Jaako, Juha

    2014-07-01

    A case study was conducted during 1994-2013 on several groups of process engineering students to see what was needed to transform a single course from a teacher-centred to a student-centred learning environment (SCLE). Development work was done incrementally, using Herbart's didactic triangle as a theoretical framework. The effects of the changes in learning environment were analysed using quantitative (student attendance, pass rate, attrition, grades) and qualitative data (student feedback). Guiding the didactic relation, i.e. the studying done by students, by continuous assessment was found to be very useful. Using SCLEs that emphasise student responsibility and activity in learning has been found in this case to enhance student learning considerably.

  9. The Analysis of Orders of Perishable Goods in Relation to the Bullwhip Effect in the Logistic Supply Chain of the Food Industry: a Case Study

    Science.gov (United States)

    Chocholáč, Jan; Průša, Petr

    2016-12-01

    The bullwhip effect generally refers to the phenomenon where order variability increases as the orders move upstream in the supply chain. It is serious problem for every member of the supply chain. This effect begins at customers and passes through the chain to producers, which are at the end of the logistic chain. Especially food supply chains are affected by this issue. These chains are unique for problems of expiration of goods (particularly perishable goods), variable demand, orders with quantity discounts and effort to maximize the customer satisfaction. This paper will present the problem of the bullwhip effect in the real supply chain in the food industry. This supply chain consists of approximately 350 stores, four central warehouses and more than 1000 suppliers, but the case study will examine 87 stores, one central warehouse and one supplier in 2015. The aim of this paper is the analysis of the order variability between the various links in this chain and confirmation of the bullwhip effect in this chain. The subject of the analysis will be perishable goods.

  10. eCompetence Case Studies

    DEFF Research Database (Denmark)

    Jensen, Helle Bækkelund

    2006-01-01

    In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches.......In this paper we present some details of the processes undertaken in the European eCompetence Initiative. We present two illustrative and representative case studies. The research aims to identify and understand patterns of individual and organisational eCompetence approaches....

  11. Assessment of the Relation between the Expression of Oxaliplatin Transporters in Colorectal Cancer and Response to FOLFOX-4 Adjuvant Chemotherapy: A Case Control Study

    Science.gov (United States)

    Le Roy, Bertrand; Tixier, Lucie; Pereira, Bruno; Sauvanet, Pierre; Buc, Emmanuel; Pétorin, Caroline; Déchelotte, Pierre; Pezet, Denis; Balayssac, David

    2016-01-01

    Background Adjuvant chemotherapy for colorectal cancer is mainly based on the combination of 5-fluorouracil, folinic acid and oxaliplatin (FOLFOX-4). The pharmacological target of oxaliplatin remains intracellular and therefore dependent on its entry into cells. The intracellular distribution of oxaliplatin is mediated by organic cation transporters 1, 2 and 3 (OCT1, 2 and 3), copper transporter 1 (CTR1) and ATPase Cu2+ transporting beta polypeptide (ATP7B) and may modulate the efficacy of oxaliplatin-based chemotherapy. The aim of this study was to perform a retrospective study to assess the relation between the expression of oxaliplatin transporters in colorectal cancer before chemotherapy and the response to FOLFOX-4 adjuvant chemotherapy in responder and non-responder patients. Methods This retrospective study was conducted at a single center (University Hospital of Clermont-Ferrand, France). The target population was patients with resectable colorectal cancer operated between 2006 and 2013. Inclusion criteria were defined for the responder patients as no cancer recurrence 3 years after the end of chemotherapy, and for the non-responder patients as cancer recurrence within 1 year. Other inclusion criteria were stages IIb–IV cancers, first-line adjuvant FOLFOX-4 chemotherapy, and the availability of resected primary tumor samples. Exclusion criteria were preoperative chemotherapy and/or radiotherapy, a targeted therapy, other anticancer drugs, cancer recurrence between the first and the third year after the end of chemotherapy and follow-up < 3 years. Immunostaining of oxaliplatin transporters (OCT1, 2, 3, CTR1 and ATP7B) and Ki-67 was assessed in tumor samples. Results Retrospectively, 31 patients have been selected according to inclusion and exclusion criteria (15 responders and 16 non-responders). Before FOLFOX-4 regimen, OCT3 expression was significantly lower in responder patients compared to non-responders (p<0.001). According to multivariate analysis

  12. Case Study on Logistics Performance

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    Shahryar Sorooshian

    2013-05-01

    Full Text Available The paper presents research carried out at a medium‐size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and we include a theoretical discussion of online data collected and a case study of the logistic performance of a real organization. The study also examines the performance of the selected company, identifies the problems and provides recommendations for improvements. This study can be a guide for business advisers and those interested in analysing company performance, especially from a logistics viewpoint. We also suggest the methodology of this case study for those who want to have a better understanding of a business environment before starting their own business, or for benchmarking practice during strategic planning.

  13. Teaching Case: Enterprise Architecture Specification Case Study

    Science.gov (United States)

    Steenkamp, Annette Lerine; Alawdah, Amal; Almasri, Osama; Gai, Keke; Khattab, Nidal; Swaby, Carval; Abaas, Ramy

    2013-01-01

    A graduate course in enterprise architecture had a team project component in which a real-world business case, provided by an industry sponsor, formed the basis of the project charter and the architecture statement of work. The paper aims to share the team project experience on developing the architecture specifications based on the business case…

  14. Relative contribution of structural inheritance and glacial morphology on the post-glacial slope destabilization. The Séchilienne slope case study (French western Alps).

    Science.gov (United States)

    Schwartz, Stéphane; Zerathe, Swann; Audin, Laurence; Dumont, Thierry; Jarre, Raphael; Jongmans, Denis; Carcaillet, Julien; Dubois, Laurent

    2016-04-01

    In the main Alpine valleys, the chronological constraints about the onset of the slope movements following glacial retreat are scarse. The southern part of the Belledonne massif (French western Alps) along the Romanche valley is affected by numerous slope destabilizations. A detailed geomorphological study using a high resolution LIDAR digital model elevation, allows to characterize the structural framework, the evolution of the glacial retreat and the distribution of the gravitational instabilities. The systematic survey of (i) the main fracturing and (ii) the glacial and gravity morphological witness along the slopes of the Romanche valley coupled with (iii) cosmogenic 10Be dating provides a regional view of the dynamics of slope destabilisation in this area. The proposed scenario allows to evaluate the relative influence of different triggering factors such as seismo-tectonic stresses and climatic changes. These data also allow to propose a consistent dynamic destabilization model of a major lanslide (> 100×106 m3) in relation with the last episode of glacial retreat ~ 21ka ago.

  15. Life Cycle Assessment in Building: A Case Study on the Energy and Emissions Impact Related to the Choice of Housing Typologies and Construction Process in Spain

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    Antonio Ángel Rodríguez Serrano

    2016-03-01

    Full Text Available While there exists an international trend to develop zero or near zero emissions building solutions by 2020, and European governments continuously update their building regulations to optimize the building envelope and energy systems to achieve this during the building use stage, at least in Spain the building regulations do not take into account the impact of emissions resulting from urbanization and construction activities prior to building use. This research studies in detail the entire emissions balance (and how it may be related to energy efficiency in a newly built residential cluster project in Mancha Real (Jaén, Spain, and influences due to the choice of different urban typologies. For comparison, terraced housing and low-density, four-floor, multi-family housing alternatives have been studied. The present work assessed the life cycle of the building with the help of commercial software (CYPE, and the energy efficiency and emissions according to the legal regulations in Spain with the official software LIDER and CALENER VYP. After a careful choice of building and systems alternatives and their comparison, the study concludes that the major emissions impact and energy costs of urbanization and building activity occurs during construction, while later savings due to reductions in building use emissions are very modest in comparison. Therefore, deeper analysis is suggested to improve the efficiency of the construction process for a significantly reduced emission footprint on the urban environment.

  16. Case study of airborne fungi according to air temperature and relative humidity in houses with semi-basements adjacent to a forested hillside.

    Science.gov (United States)

    Bamba, Ikuko; Azuma, Michiyo; Hamada, Nobuo; Kubo, Hiroko; Isoda, Norio

    2014-01-01

    We studied airborne concentrations of fungal spores and the thermal environment in houses with semi-basements surrounded by a natural forest. We examined the relationship between airborne fungi and the thermal environment, surrounding natural environment, structures of houses and use of a dehumidifier. The subject residential area was located in the northern part of Nara city, Nara prefecture, Japan. Six detached houses were included in this study. In residential areas, outdoor airborne concentrations were high during summer and autumn, correlated with humidity. The presence of Basidiomycetes was particularly notable, although the indoor concentration was lower than the outdoor level. In the semi-basement rooms, relative humidity was nearly always >80% when the residence was built; however, both the indoor humidity and fungal concentrations decreased greatly when a dehumidifier was used in this study. High levels of Aspergillus and Basidiomycetes were detected in semi-basements. Basidiomycetes are likely of outdoor origin, whereas Aspergillus might grow indoors. Moreover, the composition of fungal species differed according to room-structure and usage. Due to the health risks associated with high indoor concentrations of fungi, the utilization of the semi-basement or basement space requires adequate ventilation and dehumidification, beginning immediately after construction.

  17. The Survey of Knowledge, Attitude and Performance Of Female Barbers in Relation to Job's Environmental Health: A Case Study of Malayer City

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    Ali Almasi

    2016-07-01

    Full Text Available Hygiene disregarding and usage of contaminated tools leads to viral infections, fungal, bacterial and skin diseases, eczema, warts, tetanus and so on. Thus assessment of knowledge, attitudes and performance of barbers in order to ensure the security and public health is really necessary. This study is aimed at determining the knowledge, attitude and performance of female barbers in relation to job's environmental health in Malayer city. In present descriptive- analytical study, 75 female barbers sampling of Malayer city were selected by clusters – systematic method. The data were obtained through questionnaires for completion and checklist. Data analysis was performed using SPSS 21 statistical software. The result showed, 86.66% of people have attained correct awareness of regulations and 92.28% had positive attitude toward regulations and 86.38% of people in this study showed appropriate health practice. In order to, compare the average knowledge level in regard to parameters such as age, work experiences and income situation showed a statistically significant difference. In attitude and performance section, the difference between age and mentioned parameters was not statistically significant (P≥ 0.05. Despite the desirable level of knowledge, attitude and practice of barbers female in Malayer city, in order to improve the situation, to be better the presence of barbers in special guilds courses to train seriously.

  18. The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer: a case-control study and gene expression analyses.

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    Natalia Castaño-Rodríguez

    Full Text Available BACKGROUND: Currently, it is well established that cancer arises in chronically inflamed tissue. A number of NOD-like receptors (NLRs form inflammasomes, intracellular multiprotein complexes critical for generating mature pro-inflammatory cytokines (IL-1β and IL-18. As chronic inflammation of the gastric mucosa is a consequence of Helicobacter pylori infection, we investigated the role of genetic polymorphisms and expression of genes involved in the NLR signalling pathway in H. pylori infection and related gastric cancer (GC. MATERIALS AND METHODS: Fifty-one genetic polymorphisms were genotyped in 310 ethnic Chinese (87 non-cardia GC cases and 223 controls with functional dyspepsia. In addition, gene expression of 84 molecules involved in the NLR signalling pathway was assessed in THP-1 cells challenged with two H. pylori strains, GC026 (GC and 26695 (gastritis. RESULTS: CARD8-rs11672725, NLRP3-rs10754558, NLRP3-rs4612666, NLRP12-rs199475867 and NLRX1-rs10790286 showed significant associations with GC. On multivariate analysis, CARD8-rs11672725 remained a risk factor (OR: 4.80, 95% CI: 1.39-16.58. Further, NLRP12-rs2866112 increased the risk of H. pylori infection (OR: 2.13, 95% CI: 1.22-3.71. Statistical analyses assessing the joint effect of H. pylori infection and the selected polymorphisms revealed strong associations with GC (CARD8, NLRP3, CASP1 and NLRP12 polymorphisms. In gene expression analyses, five genes encoding NLRs were significantly regulated in H. pylori-challenged cells (NLRC4, NLRC5, NLRP9, NLRP12 and NLRX1. Interestingly, persistent up-regulation of NFKB1 with simultaneous down-regulation of NLRP12 and NLRX1 was observed in H. pylori GC026-challenged cells. Further, NF-κB target genes encoding pro-inflammatory cytokines, chemokines and molecules involved in carcinogenesis were markedly up-regulated in H. pylori GC026-challenged cells. CONCLUSIONS: Novel associations between polymorphisms in the NLR signalling pathway (CARD8

  19. Thinking Relationally about Studying "Up"

    Science.gov (United States)

    Stich, Amy E.; Colyar, Julia E.

    2015-01-01

    In this paper, the authors argue that despite a resurgence of elite studies, the majority of existing scholarship works to reify and legitimize social inequality through its language and method. In particular, the authors utilize Pierre Bourdieu's concept of relational thinking to review and critique contemporary research on elite education and…

  20. Aerospace Mechanisms and Tribology Technology: Case Study

    Science.gov (United States)

    Miyoshi, K.

    1999-01-01

    This paper focuses attention on tribology technology practice related to vacuum tribology. A case study describes an aspect of a real problem in sufficient detail for the engineer and scientist to understand the tribological situation and the failure. The nature of the problem is analyzed and the tribological properties are examined.

  1. Aerospace Mechanisms and Tribology Technology: Case Studies

    Science.gov (United States)

    Miyoshi, Kazuhisa

    1999-01-01

    This chapter focuses attention on tribology technology practice related to vacuum tribology and space tribology. Two case studies describe aspects of real problems in sufficient detail for the engineer and the scientist to understand the tribological situations and the failures. The nature of the problems is analyzed and the range of potential solutions is evaluated. Courses of action are recommended.

  2. Analysis of the relation between emotional intelligence of leaders of different sectors of a big multinational organization and the organizational climate: a case study

    Directory of Open Access Journals (Sweden)

    Daniel Ramos Deschauer

    2008-09-01

    Full Text Available The business community has been marked, in the last decades, by an incessant quest for competitiveness in order to survive and grow in a globalized world. Companies have had to revamp their structures, find new paths and make economic changes. Managers have been forced to undertake increased responsibilities and commitment to their organizations, they also had to adjust their profiles and review their individual abilities and competences, mostly because of their impact on the organizational climate perceived by employees. In this sense, the object of this study is to identify relations between emotional quotient of managers at different hierarchical levels within the organization and the organizational climate as perceived by each manager’s team of collaborators. In addition to new surveys on the leader’s emotional intelligence and organizational climate, this study points to the need for programs focusing on the development of managers’ emotional abilities, as a way of improving organizational climate and, as a result, keeping up the company’s intellectual capital as a strategy for organizational success.

  3. Concentrations of Available Heavy Metals in Mediterranean Agricultural Soils and their Relation with Some Soil Selected Properties: A Case Study in Typical Mediterranean Soils

    Directory of Open Access Journals (Sweden)

    José Rato Nunes

    2014-12-01

    Full Text Available The characterization of the content of trace metals in soils is an instrument in many programs of environmental protection, including the establishment of regional-level standards to detect sites affected by contamination. The objectives of the present study were to study the available levels of Cd, Cr, Cu, Ni, Pb, and Zn in surface horizons of agricultural soils in a typical European Mediterranean region, to establish the geochemical baseline concentration (GBC, background level (BL, and reference value (RV of each of these available metals, and to investigate their possible correlations with soil properties. To establish the GBC and RV values, we used the “standard threshold method”. Topsoil samples (0–20 cm were collected from 630 sites, and extracted with Diethylene Triamine Pentaacetic Acid (DTPA to determine their available heavy metal concentrations. The GBC values established were: 0.04 to 0.90 mg kg−1, 0.70 to 2.50 mg kg−1, 0.10 to 6.30 mg kg−1, 0.30 to 7.90 mg kg−1, 0.29 to 4.50 mg kg−1, and 0.18 to 2.50 mg kg−1 for Cd, Cr, Cu, Ni, Pb, and Zn, respectively. Soil properties were found to be correlated with the available heavy metal content, suggesting that the enhanced mobility of heavy metals are related to anthropic activities.

  4. Piped water consumption in Ghana: A case study of temporal and spatial patterns of clean water demand relative to alternative water sources in rural small towns.

    Science.gov (United States)

    Kulinkina, Alexandra V; Kosinski, Karen C; Liss, Alexander; Adjei, Michael N; Ayamgah, Gilbert A; Webb, Patrick; Gute, David M; Plummer, Jeanine D; Naumova, Elena N

    2016-07-15

    Continuous access to adequate quantities of safe water is essential for human health and socioeconomic development. Piped water systems (PWSs) are an increasingly common type of water supply in rural African small towns. We assessed temporal and spatial patterns in water consumption from public standpipes of four PWSs in Ghana in order to assess clean water demand relative to other available water sources. Low water consumption was evident in all study towns, which manifested temporally and spatially. Temporal variability in water consumption that is negatively correlated with rainfall is an indicator of rainwater preference when it is available. Furthermore, our findings show that standpipes in close proximity to alternative water sources such as streams and hand-dug wells suffer further reductions in water consumption. Qualitative data suggest that consumer demand in the study towns appears to be driven more by water quantity, accessibility, and perceived aesthetic water quality, as compared to microbiological water quality or price. In settings with chronic under-utilization of improved water sources, increasing water demand through household connections, improving water quality with respect to taste and appropriateness for laundry, and educating residents about health benefits of using piped water should be prioritized. Continued consumer demand and sufficient revenue generation are important attributes of a water service that ensure its function over time. Our findings suggest that analyzing water consumption of existing metered PWSs in combination with qualitative approaches may enable more efficient planning of community-based water supplies and support sustainable development.

  5. The Case Study of Frank

    Science.gov (United States)

    Eynde, Peter Op't; Hannula, Markku S.

    2006-01-01

    As a unifying feature of this Special Issue, we have asked proponents of each framework to analyse an empirical classroom account of one student's process of solving a mathematical problem. Here, for the case study of "Frank", we give the main data that were available to all authors.

  6. Case Studies in Sports Nutrition.

    Science.gov (United States)

    Clark, Nancy

    1988-01-01

    This article presents case studies of two athletes who wanted to affect a change in their body weight in order to enhance athletic performance. Each athlete's problem and the nutrition approach used to solve it are discussed. Caloric values of fast foods are listed. (JL)

  7. The reflexive case study method

    DEFF Research Database (Denmark)

    Rittenhofer, Iris

    2015-01-01

    This paper extends the international business research on small to medium-sized enterprises (SME) at the nexus of globalization. Based on a conceptual synthesis across disciplines and theoretical perspectives, it offers management research a reflexive method for case study research of postnational...

  8. Overview of the Case Studies

    DEFF Research Database (Denmark)

    Cameron, Ian; Gani, Rafiqul

    2011-01-01

    A series of case studies are used to illustrate many of the underlying modelling principles within the book. To facilitate this, the ICAS-MoT modelling tool has been used. A wide range of application areas have been chosen to ensure that the principal concepts of effective and efficient modelling...

  9. Equatorial jet - a case study

    Digital Repository Service at National Institute of Oceanography (India)

    Muraleedharan, P.M.; PrasannaKumar, S.

    Detailed EOF analysis of wind data reportEd. by Wunsch over Gan (00 degrees 41'S; 73 degrees 10'E) is made for the period 1963-70. The year 1964, which exhibited least variability from mean wind structure, has been chosen for the case study. EOF...

  10. Patient-focused measures of functional health status and health-related quality of life in pediatric orthopedics: A case study in measurement selection

    Directory of Open Access Journals (Sweden)

    Barr Ronald D

    2005-01-01

    Full Text Available Abstract The objectives of this report are to review the assessment of patient-focused outcomes in pediatric orthopedic surgery, to describe a framework for identifying appropriate sets of measures, and to illustrate an application of the framework to a challenging orthopedic problem. A detailed framework of study design and measurement factors is described. The factors are important for selecting appropriate instruments to measure health status and health-related quality of life (HRQL in a particular context. A study to evaluate treatment alternatives for patients with neurofibromatosis type 1 and congenital tibial dysplasia (NF1-CTD provides a rich illustration of the application of the framework. The application involves great variability in the instrument selection factors. Furthermore, these patients and their supportive caregivers face numerous complex health challenges with long-term implications for HRQL. Detailed summaries of important generic preference-based multi-attribute measurement systems, pediatric health profile instruments, and pediatric orthopedic-specific instruments are presented. Age-appropriate generic and specific measures are identified for study of NF1-CTD patients. Selected measures include the Activities Scale for Children, Gillette Functional Assessment Questionnaire Walking Scale, Health Utilities Index, and Pediatric Inventory of Quality of Life. Reliable and valid measures for application to pediatric orthopedics are available. There are important differences among measures. The selected measures complement each other. The framework in this report provides a guide for selecting appropriate measures. Application of appropriate sets of measures will enhance the ability to describe the morbidity of pediatric orthopedic patients and to assess the effectiveness of alternative clinical interventions. The framework for measurement of health status and HRQL from a patient perspective has relevance to many other areas of

  11. Nanomaterial Case Study: A Comparison of Multiwalled ...

    Science.gov (United States)

    The draft document is intended to be used as part of a process to identify what is known and, more importantly, what is not yet known that could be of value in assessing the broad implications of specific nanomaterials. Like previous case studies (see History/ Chronology below), this draft case study on multiwalled carbon nanotubes (MWCNTs) is based on the comprehensive environmental assessment (CEA) approach, which consists of both a framework and a process. Unlike previous case studies this case study incorporates information about a traditional (i.e., “non-nano-enabled”) product, against which the MWCNT flame-retardant coating applied to upholstery textiles (i.e., the “nano-enabled” product) can be compared. The comparative element serves dual-purposes: 1) to provide a more robust database that facilitates identification of data gaps related to the nano-enabled product and 2) to provide a context for identifying key factors and data gaps for future efforts to evaluate risk-related trade-offs between a nano-enabled and non-nano-enabled product. This draft case study does not represent a completed or even a preliminary assessment of MWCNTs; rather, it uses the CEA framework to structure information from available literature and other resources (e.g., government reports) on the product life cycle, fate and transport processes in various environmental media, exposure-dose characterization, and impacts in human, ecological, and environmental receptors.

  12. Primary healthcare system capacities for responding to storm and flood-related health problems: a case study from a rural district in central Vietnam

    Directory of Open Access Journals (Sweden)

    Hoang Van Minh

    2014-12-01

    Full Text Available Background: As a tropical depression in the East Sea, Vietnam is greatly affected by climate change and natural disasters. Knowledge of the current capacity of the primary healthcare system in Vietnam to respond to health issues associated with storms and floods is very important for policy making in the country. However, there has been little scientific research in this area. Objective: This research was to assess primary healthcare system capacities in a rural district in central Vietnam to respond to such health issues. Design: This was a cross-sectional descriptive study using quantitative and qualitative approaches. Quantitative methods used self-administered questionnaires. Qualitative methods (in-depth interviews and focus groups discussions were used to broaden understanding of the quantitative material and to get additional information on actions taken. Results: 1 Service delivery: Medical emergency services, especially surgical operations and referral systems, were not always available during the storm and flood seasons. 2 Governance: District emergency plans focus largely on disaster response rather than prevention. The plans did not clearly define the role of primary healthcare and had no clear information on the coordination mechanism among different sectors and organizations. 3 Financing: The budget for prevention and control of flood and storm activities was limited and had no specific items for healthcare activities. Only a little additional funding was available, but the procedures to get this funding were usually time-consuming. 4 Human resources: Medical rescue teams were established, but there were no epidemiologists or environmental health specialists to take care of epidemiological issues. Training on prevention and control of climate change and disaster-related health issues did not meet actual needs. 5 Information and research: Data that can be used for planning and management (including population and epidemiological

  13. Lidocaine-prilocaine cream reduces catheter-related bladder discomfort in male patients during the general anesthesia recovery period: A prospective, randomized, case-control STROBE study.

    Science.gov (United States)

    Mu, Li; Geng, Li-Cheng; Xu, Hui; Luo, Man; Geng, Jing-Miao; Li, Li

    2017-04-01

    Urethral catheterization is a predictor of agitation during the general anesthesia recovery period. The aim of this study was to determine the effect of intraurethral 5% lidocaine and 25 mg/g prilocaine cream in reducing catheter-related bladder discomfort (CRBD) in male patients during the general anesthesia recovery period. Adult male patients undergoing elective operations that required urinary catheterization under general anesthesia were enrolled and assigned randomly to 2 groups. In the lidocaine-prilocaine cream group (n = 72), approximately 5 g of topical cream was spread in the preputial sac, the glans, the meatus, and on the urinary catheter surface before urinary catheterization. In the control group (n = 74), the urinary catheter was lubricated with lidocaine gel. The incidence and severity of CRBD were assessed 15, 30, 45, and 60 minutes postoperatively. We found that the incidence of CRBD in the lidocaine-prilocaine cream group was significantly lower than in the control group. Multivariate logistic regression analysis showed that lidocaine-prilocaine cream applications reduced moderate or severe CRBD. Thirty minutes postoperation was the most frequent time point for the incidence of CRBD. Application of lidocaine-prilocaine cream on the surface of the urinary catheter is an efficient and safe method to reduce the incidence and severity of CRBD.

  14. A Case Study On the Relative Influence of Free Tropospheric Subsidence, Long Range Transport and Local Production in Modulating Ozone Concentrations over Qatar

    Science.gov (United States)

    Ayoub, Mohammed; Ackermann, Luis; Fountoukis, Christos; Gladich, Ivan

    2016-04-01

    The Qatar Environment and Energy Research Institute (QEERI) operates a network of air quality monitoring stations (AQMS) around the Doha metropolitan area and an ozonesonde station with regular weekly launches and occasional higher frequency launch experiments (HFLE). Six ozonesondes were launched at 0700 LT/0400 UTC and 1300 LT/1000 UTC over a three day period between 10-12 September, 2013. We present the analysis of the ozonesonde data coupled with regional chemical transport modeling over the same time period using WRF-Chem validated against both the ozonesonde and surface AQMS measurements. The HFLE and modeling show evidence of both subsidence and transboundary transport of ozone during the study period, coupled with a strong sea breeze circulation on the 11th of September resulting in elevated ozone concentrations throughout the boundary layer. The development of the sea breeze during the course of the day and influence of the early morning residual layer versus daytime production is quantified. The almost complete titration of ozone in the morning hours of 11 September, 2013 is attributed to local vehicular emissions of NOx and stable atmospheric conditions prevailing over the Doha area. The relative contribution of long range transport of ozone along the Arabian Gulf coast and local urban emissions are discussed.

  15. Association between the DTNBP1 gene and intelligence: a case-control study in young patients with schizophrenia and related disorders and unaffected siblings

    Directory of Open Access Journals (Sweden)

    Tanck Michael W

    2007-04-01

    Full Text Available Abstract Background The dystrobrevin-binding protein 1 (DTNBP1 gene is a susceptibility gene for schizophrenia. There is growing evidence that DTNPB1 contributes to intelligence and cognition. In this study, we investigated association between single nucleotide polymorphisms (SNPs in the DTNBP1 gene and intellectual functioning in patients with a first episode of schizophrenia or related psychotic disorder (first-episode psychosis, FEP, their healthy siblings, and unrelated controls. Methods From all subjects IQ measurements were obtained (verbal IQ [VIQ], performance IQ [PIQ], and full scale IQ [FSIQ]. Seven SNPs in the DTNBP1 gene were genotyped using single base primer extension and analyzed by matrix-assisted laser deionization mass spectrometry (MALDI-TOF. Results Mean VIQ, PIQ, and FSIQ scores differed significantly (p Conclusion Although preliminary, our results provide evidence for association between the DTNBP1 gene and intelligence in patients with FEP and their unaffected siblings. Genetic variation in the DTNBP1 gene may increase schizophrenia susceptibility by affecting intellectual functioning.

  16. A general risk-based adaptive management scheme incorporating the Bayesian Network Relative Risk Model with the South River, Virginia, as case study.

    Science.gov (United States)

    Landis, Wayne G; Markiewicz, April J; Ayre, Kim K; Johns, Annie F; Harris, Meagan J; Stinson, Jonah M; Summers, Heather M

    2017-01-01

    Adaptive management has been presented as a method for the remediation, restoration, and protection of ecological systems. Recent reviews have found that the implementation of adaptive management has been unsuccessful in many instances. We present a modification of the model first formulated by Wyant and colleagues that puts ecological risk assessment into a central role in the adaptive management process. This construction has 3 overarching segments. Public engagement and governance determine the goals of society by identifying endpoints and specifying constraints such as costs. The research, engineering, risk assessment, and management section contains the decision loop estimating risk, evaluating options, specifying the monitoring program, and incorporating the data to re-evaluate risk. The 3rd component is the recognition that risk and public engagement can be altered by various externalities such as climate change, economics, technological developments, and population growth. We use the South River, Virginia, USA, study area and our previous research to illustrate each of these components. In our example, we use the Bayesian Network Relative Risk Model to estimate risks, evaluate remediation options, and provide lists of monitoring priorities. The research, engineering, risk assessment, and management loop also provides a structure in which data and the records of what worked and what did not, the learning process, can be stored. The learning process is a central part of adaptive management. We conclude that risk assessment can and should become an integral part of the adaptive management process. Integr Environ Assess Manag 2017;13:115-126. © 2016 SETAC.

  17. Soil Fertility in relation to Landscape Position and Land Use/Cover Types: A Case Study of the Lake Kivu Pilot Learning Site

    Directory of Open Access Journals (Sweden)

    Majaliwa Mwanjalolo Jackson-Gilbert

    2015-01-01

    Full Text Available This study determined the change and distribution of land-uses/covers along the landscape, and evaluated the nutrient status of the top soil layer in the Lake Kivu Pilot Learning Site (LKPLS benchmarked micro-catchments. Soil physical and chemical properties were quantified using triplicate soil samples collected from each land-use/cover at two depths (0–15 and 15–30 cm in three LK PLS Learning Innovation Platform (IP sites (Bufundi in Uganda, Mupfuni-Shanga in D.R. Congo, Gataraga in Rwanda. Small scale agriculture has increased in all the benchmarked micro-catchments at the expense of other land-uses/covers. In the settlement areas land-use/cover distribution along the landscape varied across sites and countries; the major one being eucalyptus woodlots, wetland, and perennials and annuals crops in Bufundi; annuals and perennials crops in Mupfuni-Shanga; and annuals crops in Gataraga. Perennial crops tended to occur at the footslope and valley bottoms, while the annuals occurred at the upper backslopes and summits. Available P and K were relatively higher and C/N ratio (7.28 was the lowest in Mupfuni Shanga. Annual crops had the lowest available P and N across site (P<0.05. The key nutrients N, P and K were below the critical values for plant growth for Bufundi.

  18. Can You Judge a Disease Host by the Company It Keeps? Predicting Disease Hosts and Their Relative Importance: A Case Study for Leishmaniasis

    Science.gov (United States)

    Stephens, Christopher R.; Sánchez-Cordero, Víctor; Becker, Ingeborg; Rebollar-Tellez, Eduardo; Rodríguez-Moreno, Ángel; Berzunza-Cruz, Miriam; Domingo Balcells, Cristina; Gutiérrez-Granados, Gabriel; Hidalgo-Mihart, Mircea; Ibarra-Cerdeña, Carlos N.; Ibarra López, Martha Pilar; Iñiguez Dávalos, Luis Ignacio; Ramírez Martínez, María Magdalena

    2016-01-01

    Zoonoses are an important class of infectious diseases. An important element determining the impact of a zoonosis on domestic animal and human health is host range. Although for particular zoonoses some host species have been identified, until recently there have been no methods to predict those species most likely to be hosts or their relative importance. Complex inference networks infer potential biotic interactions between species using their degree of geographic co-occurrence, and have been posited as a potential tool for predicting disease hosts. Here we present the results of an interdisciplinary, empirical study to validate a model based on such networks for predicting hosts of Leishmania (L.) mexicana in Mexico. Using systematic sampling to validate the model predictions we identified 22 new species of host (34% of all species collected) with the probability to be a host strongly dependent on the probability of co-occurrence of vector and host. The results confirm that Leishmania (L.) mexicana is a generalist parasite but with a much wider host range than was previously thought. These results substantially change the geographic risk profile for Leishmaniasis and provide insights for the design of more efficient surveillance measures and a better understanding of potential dispersal scenarios. PMID:27716833

  19. The relative roles of climate and land use in the degradation of a terrestrial ecosystem: a case study from Kjarardalur, West Iceland

    Science.gov (United States)

    Erlendsson, Egill; Gísladóttir, Guðrún

    2016-04-01

    Around AD 870 the virgin environment of Iceland became populated by humans and mammal land herbivores. Since then, the island has lost nearly all of its native birch woodland, resulting in dramatic degradation of landscapes and ecosystems, attributed mainly to over-exploitation of woodlands and late-medieval climate deterioration. As part of policy making in agriculture, a heated debate is ongoing over limitations to sheep grazing in pastures suffering from long-term degradation. In this context the history of climate and land use is of great importance. Those who consider grazing a minimal attribute to land degradation argue that the harsh climate conditions of the little ice age are the primary mechanism behind the current degraded landscape. Others err on the side of caution and propose a careful approach to grazing. This study forms a contribution to the historical context of the impact of grazing upon the Icelandic terrestrial ecosystem. Using the analyses of pollen and spores from coprophilous fungi as principal methods, we present data about historical environmental change from within two different land holdings in Kjarardalur Valley, West Iceland. One dataset comes from within a landholding governed by the chieftain farm Reykholt, the other comes from within the land of the indipendent farm, Norðtunga. In the past the valley was used primarily as a pasture, associated with shielings (organised seasonal grazing). Pollen data from the pasture in Kjarardalur Valley, West Iceland, demonstrate a rapid loss of birch (Betula pubescens) woodland from grazing areas owned by the major farm and institution, Reykholt. The suppressive nature of grazing is demonstrated by the expansion of woodland as soon when animal stocks are reduced, probably as a consequence of the bubonic plague after AD 1402. Resumed exploitation of resources eventually depleted all birch woodland from the Reykholt landholding and precipitated soil erosion. The trajectory of environmental change

  20. Studying Intergroup Relations in Organizations.

    Science.gov (United States)

    1980-01-10

    23, 137-149. Sumner, W.G.: Folkways. New York; Ginn, 1906. Tajfel , H.: Experiments in Intergroup Discrimination . Scientific American, 1970, 223, 96-102...Shepard and Mouton’s (1964) subsequent studies and application to managerial behavior. Tajfel (1971) has carried out an extensive series of experiments on...and to influ- ence relations with other groups (Sherif and Sherif, 1969; Blake, Shepard, and Mouton, 1964; Tajfel , 1971; Billig, 1976). e. Leadership

  1. Effect of an armed conflict on relative socioeconomic position of rural households: case study from western Côte d'Ivoire

    Directory of Open Access Journals (Sweden)

    Fürst Thomas

    2010-08-01

    Full Text Available Abstract Background Current conceptual frameworks on the interrelationship between armed conflict and poverty are based primarily on aggregated macro-level data and/or qualitative evidence and usually focus on adherents of warring factions. In contrast, there is a paucity of quantitative studies about the socioeconomic consequences of armed conflict at the micro-level, i.e., noncommitted local households and civilians. Methods We conducted a secondary analysis of data pertaining to risk factors for malaria and neglected tropical diseases. Standardized questionnaires were administered to 182 households in a rural part of western Côte d'Ivoire in August 2002 and again in early 2004. Between the two surveys, the area was subject to intensive fighting in the Ivorian civil war. Principal component analysis was applied at the two time points for constructing an asset-based wealth-index and categorizing the households in wealth quintiles. Based on quintile changes, the households were labeled as 'worse-off', 'even' or 'better-off'. Statistical analysis tested for significant associations between the socioeconomic fates of households and head of household characteristics, household composition, village characteristics and self-reported events associated with the armed conflict. Most-poor/least-poor ratios and concentration indices were calculated to assess equity changes in households' asset possession. Results Of 203 households initially included in the first survey, 21 were lost to follow-up. The population in the remaining 182 households shrunk from 1,749 to 1,625 persons due to migration and natural population changes. However, only weak socioeconomic dynamics were observed; every seventh household was defined as 'worse-off' or 'better-off' despite the war-time circumstances. Analysis of other reported demographic and economic characteristics did not clearly identify more or less resilient households, and only subtle equity shifts were noted

  2. Late Quaternary environmental change inferred from phytoliths and other soil-related proxies: Case studies from the central and southern Great Plains, USA

    Science.gov (United States)

    Cordova, C.E.; Johnson, W.C.; Mandel, R.D.; Palmer, M.W.

    2011-01-01

    This study investigates stable carbon isotopes (??13C), opal phytolith assemblages, burnt phytoliths, microscopic charcoal and Sporormiella spores from modern soils and paleosols in Kansas and Oklahoma. Grass and dicot phytoliths in combination with ??13C are used as proxies for reconstructing the structure of grasslands and woodlands. Burnt grass phytoliths and microscopic charcoal are evaluated as proxies for reconstructing paleofire incidence. Concentrations of the fungal spore Sporormiella are used as a proxy for assessing large herbivore activity. These proxies were tested on various modern grassland communities of the central and southern Great Plains, including areas with bison, cattle, and small herbivores, and areas under different fire frequencies.Opal phytolith assemblages and ??13C values show that before cal 11ka, C3 grasses and woody plants predominated in areas that today are dominated by C4 grasses. The origin of the shortgrass prairie dates back to about cal 10ka. The origin of the tallgrass prairie, however, is not clear as phytolith data show variable assemblages throughout the Holocene (mixed-grass, tallgrass, and tallgrass-woodland mosaic). Different proxies (burnt phytoliths vs. charcoal) reveal different fire frequencies, but it is apparent that microfossil evidence for fire incidence is closely related to the abundance of woody plants in the landscape.Before cal 12. ka, soils show somewhat elevated concentration of Sporormiella, but lower concentrations than the modern high-density bison and cattle grazing areas. Throughout the Holocene, Sporormiella frequencies are low, which suggests lower large ungulate densities and perhaps high mobility. ?? 2010 Elsevier B.V.

  3. Grammatical gender in German: a case for linguistic relativity?

    Science.gov (United States)

    Bender, Andrea; Beller, Sieghard; Klauer, Karl Christoph

    2011-09-01

    The "principle of linguistic relativity" holds that, by way of grammatical categorization, language affects the conceptual representations of its speakers. Formal gender systems are a case in point, albeit a particularly controversial one: Previous studies obtained broadly diverging data, thus giving rise to conflicting conclusions. To a large extent, this incoherence is related to task differences and methodological problems. Here, a priming design is presented that avoids previous problems, as it prevents participants from employing gender information in a strategic manner. Four experiments with German native speakers show priming effects of the prime's grammatical gender on animate and nonanimate targets, an effect for the prime's biological gender on animate targets, but no effect for the prime's biological gender on nonanimate targets, and thus speak against an effect of language on thought for German gender.

  4. A Relative Ranking Approach for Nano-Enabled Applications to Improve Risk-Based Decision Making: A Case Study of Army Materiel

    Science.gov (United States)

    2014-12-24

    in energy and sensor applications , and carbon nanotubes (CNT) also ranked relatively high based on worker inha- lation from CNTs used in research and...accidental expo- sures to carbon nanotubes and copper flakes incorporated into energy and obscurant materiel by Army workers rank highest relative to...that inhalation from accidental exposures to carbon nanotubes and copper flakes incorporated into energy and obscurant materiel by Army workers rank

  5. Fold-related fractures - a brittle tectonic case study of the Helvetic zone in Vorarlberg (western Austria) and Upper Allgäu (Bavaria)

    Science.gov (United States)

    Zerlauth, M.

    2012-04-01

    Michael Zerlauth1,2 , Marcel Schulz1,2 , Hugo Ortner1 , Bernhard Fügenschuh1, Christian Zangerl2 1 Institut für Geologie und Paläontologie, Leopold Franzens Universität, 6020 Innsbruck, Austria 2 alpS-Gmbh, 6020 Innsbruck, Austria In the eastern Alps the Helvetic units exposed at the surface form a narrow belt restricted to the westernmost part of Austria and the northerly adjacent southernmost part of Bavaria. The Helvetic zone represents a Tertiary fold-and-thrust belt made up of Jurassic to Cretaceous shelf sediments deposited on the European margin of the Eurasian plate. In the course of an industry-funded project, the potential of these units for deep hydro-geothermal energy is investigated. Potential targets for hydrothermal exploration are more or less thick carbonate sequences that can be traced throughout the Helvetic zone, namely the Late Jurassic Quinten Limestone and the Early Cretaceous Schrattenkalk-Fm. In depths of at least 3000m below sea level, that have to be drilled to gain water with at least 90°C, uncemented fractures at any scale are the only cavities within these carbonates to be expected. Therefore, brittle structures are studied at differing scales of observation; aerial photos and surface outcrops are analyzed as well as thin sections. All the data obtained so far were collected in areas deformed homogenously: measuring stations were located outside large scale shear zones and either in fold-limbs or hinge zones. A constantly geometrical relationship between the orientation of the various fractures, the sedimentary layering and the trace of the axial planes can be inferred, as already stated by Hancock (1985). Besides extension fractures, veins and stylolithes, conjugated hybrid and shear fractures are quite common, indicating layer-parallel shortening normal to the axial planes as well as axial elongation. Hence, all of the structures observed can be genetically linked with thrusting and folding during regional N-S compressional

  6. Integrating Ethics into Case Study Assignments

    Directory of Open Access Journals (Sweden)

    Pamela A. Marshall

    2014-08-01

    Full Text Available I teach an upper-level writing course, Genes, Race, Gender, and Society, designed for Life Science majors, in which I utilize a case study to expose students to ethical ways of thinking.  Students first work through the topical case study and then are challenged to rethink their responses through the lenses of ethics, taking into account different ethical frameworks.  Students then develop their own case study, integrating ethical components.  I want to expose my students to this way of thinking because I see technology being driven by the Jurassic Park phenomenon, "Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should." and want future physicians grounded in a sense of how their actions relate to the greater good.

  7. Shuttle Case Study Collection Website Development

    Science.gov (United States)

    Ransom, Khadijah S.; Johnson, Grace K.

    2012-01-01

    As a continuation from summer 2012, the Shuttle Case Study Collection has been developed using lessons learned documented by NASA engineers, analysts, and contractors. Decades of information related to processing and launching the Space Shuttle is gathered into a single database to provide educators with an alternative means to teach real-world engineering processes. The goal is to provide additional engineering materials that enhance critical thinking, decision making, and problem solving skills. During this second phase of the project, the Shuttle Case Study Collection website was developed. Extensive HTML coding to link downloadable documents, videos, and images was required, as was training to learn NASA's Content Management System (CMS) for website design. As the final stage of the collection development, the website is designed to allow for distribution of information to the public as well as for case study report submissions from other educators online.

  8. Toxicological investigation of forensic cases related to the designer drug 3,4-methylenedioxypyrovalerone (MDPV): Detection, quantification and studies on human metabolism by GC-MS.

    Science.gov (United States)

    Grapp, Marcel; Kaufmann, Christoph; Ebbecke, Martin

    2017-02-02

    3,4-methylenedioxypyrovalerone (MDPV) is a synthetic cathinone belonging to the class of α-pyrrolidinophenones that become increasingly popular as a designer psychostimulant. Here, we report a comprehensive collection of MDPV exposure with quantitative serum level confirmation in Germany. During the years 2014-2016, we could proof consumption of MDPV in 23 cases where urine and blood samples were submitted to our laboratory by the police of Lower Saxony. Most of the samples underwent systematic toxicological analysis by gas chromatography-mass spectrometry (GC-MS), where MDPV could be detected in urine and/or serum samples. The determined concentrations of MDPV in serum showed a high variability, ranging from traces (<10ng/mL) up to 576ng/mL with a mean concentration of 118ng/mL and median of 47ng/mL. The majority of MDPV users were men (87%) and the age ranged from 23 to 49 years (mean 35.9, median 37 years). For most of the analytically confirmed MDPV cases we could prove co-consumption of other psychotropic drugs with frequent occurrence of opiates and cannabinoids in 22% of the cases, followed by benzodiazepines and cocaine in 17%. Analysis of urine samples by GC-MS disclosed the presence of MDPV and its metabolites 2'-oxo-MDPV, demethylenyl-MDPV, demethylenyl-methyl-MDPV, demethylenyl-oxo-MDPV, demethylenyl-methyl-oxo-MDPV and demethylenyl-methyl-N,N-bisdealkyl-MDPV. The metabolite pattern substantiates previous suggestions for principle metabolic pathways of MDPV in humans.

  9. Applying the nominal group technique in an employment relations conflict situation: A case study of a university maintenance section in South Africa

    Directory of Open Access Journals (Sweden)

    Cornelis (Kees S. van der Waal

    2009-04-01

    Full Text Available After a breakdown in employment relations in the maintenance section of a higher education institution, the authors were asked to intervene in order to try and solve the employment relations conflict situation. It was decided to employ the Nominal Group Technique (NGT as a tool in problem identification during conflict in the workplace. An initial investigation of documentation and interviews with prominent individuals in the organisation was carried out. The NGT was then used in four focus group discussions to determine the important issues as seen by staff members. The NGT facilitates the determination of shared perceptions and the ranking of ideas. The NGT was used in diverse groups, necessitating adaptations to the technique. The perceived causes of the conflict were established. The NGT can be used in a conflict situation in the workplace in order to establish the perceived causes of employment relations conflict.

  10. Studies relating to human intrusion into a repository. Report pertaining to work package 11. Preliminary safety case of the Gorleben site (VSG)

    Energy Technology Data Exchange (ETDEWEB)

    Beuth, Thomas; Buhmann, Dieter; Fischer-Appelt, Klaus; Moenig, Joerg; Ruebel, Andre; Wolf, Jens [Gesellschaft fuer Anlagen- und Reaktorsicherheit mbH (GRS), Koeln (Germany); Bollingerfehr, Wilhelm; Filbert, Wolfgang [DBE Technology GmbH, Peine (Germany); Charlier, Frank [international nuclear safety engineering gmbh (nse), Aachen (Germany); Baltes, Bruno

    2014-10-15

    The question of the long-term safety of a repository system is inseparably linked with the intensive technical examination of the possible future evolution of the site and the repository system e. g. as a result of climatic, geologic, waste-related and repository-related processes. Here, the possible evolutions to be considered are those that have the potential to have a negative impact on the intended, furthest-possible, immediate, and lasting isolation of the radioactive waste in a defined area around the underground workings of the repository mine in salt rock, which is referred to as the containment-providing rock zone (CPRZ).

  11. A case study of Impetigo

    Directory of Open Access Journals (Sweden)

    Mansouri P

    1993-05-01

    Full Text Available This is a report of a case study on 234 patients with impetigo who referred to Razi Dermatology Hospital from April to November, 1989. Treatment was started immediately after obtaining direct smear and performing culture and antibiotic sensitivity test. The most common organism responsible for impetigo was the coagulase-positive staphylococcus (71%. In 13.7% of the cases, the coagulase-negative staphylococcus was grown on culture media, but none of the cultures showed streptococcus as the main organism. Treatment was started with oral penicillin V, oral erythromycin, benzathine penicillin G injection, oral cephalexin, and topical fuccidin. Clinical and bacteriological evaluation after 3-7 days showed that it is preferable to use oral cephalexin instead of other protocols such as oral erythromycin, which has previously been the drug of choice for impetigo. In addition, topical fuccidin with a 75% curative rate was the first drug for treatment, with the same effect as the oral cephalexin

  12. Method for identifying drivers, barriers and synergies related to the deployment of a CO2 pipeline network : A case study for the Iberian Peninsula and Morocco

    NARCIS (Netherlands)

    Berghout, Niels; Cabal, Helena; Gouveia, João Pedro; van den Broek, Machteld; Faaij, André

    2015-01-01

    This paper provides a method to identify drivers, barriers and synergies (DBS) related to the deployment of a CO2 pipeline network. The method was demonstrated for the West Mediterranean region (WMR) (i.e. Spain, Portugal and Morocco). The method comprises a literature review, analysis of

  13. The Relative Quality and Cost-Effectiveness of Private and Public Schools for Low-Income Families: A Case Study in a Developing Country

    Science.gov (United States)

    Tooley, James; Dixon, Pauline; Shamsan, Yarim; Schagen, Ian

    2010-01-01

    The "mushrooming" of private schools for low-income families has been widely noted in the literature; however, very little is known about the quality of these schools. This research explored the relative quality of private unaided (recognised and unrecognised) and government schools in low-income areas of Hyderabad, India. A preliminary…

  14. Using Relative Improvement over Chance (RIOC) to Examine Agreement between Tests: Three Case Examples Using Studies of Developmental Coordination Disorder (DCD) in Children

    Science.gov (United States)

    Cairney, John; Streiner, David L.

    2011-01-01

    Although statistics such as kappa and phi are commonly used to assess agreement between tests, in situations where the base rate of a disorder in a population is low or high, these statistics tend to underestimate actual agreement. This can occur even if the tests are good and the classification of subjects is adequate. Relative improvement over…

  15. The Relative Quality and Cost-Effectiveness of Private and Public Schools for Low-Income Families: A Case Study in a Developing Country

    Science.gov (United States)

    Tooley, James; Dixon, Pauline; Shamsan, Yarim; Schagen, Ian

    2010-01-01

    The "mushrooming" of private schools for low-income families has been widely noted in the literature; however, very little is known about the quality of these schools. This research explored the relative quality of private unaided (recognised and unrecognised) and government schools in low-income areas of Hyderabad, India. A preliminary census to…

  16. JARID1A, JMY, and PTGER4 polymorphisms are related to ankylosing spondylitis in Chinese Han patients: a case-control study.

    Directory of Open Access Journals (Sweden)

    Wei Chai

    Full Text Available Susceptibility to ankylosing spondylitis (AS is largely genetically determined. JARID1A, JMY and PTGER4 have recently been found to be associated with AS in patients of western European descent. We aim to examine the influence of JARID1A, JMY, and PTGER4 polymorphisms on the susceptibility to and the severity of ankylosing spondylitis in Chinese ethnic majority Han population. This work can lead the clinical doctors to intervene earlier. Blood samples were drawn from 396 AS patients and 404 unrelated healthy controls. Both the AS patients and the controls are Han Chinese. The AS patients are classified based on the severity of the disease. Thirteen tag single nucleotide polymorphisms (tagSNPs in JARID1A, JMY and PTGER4 are selected and genotyped. Frequencies of different genotypes and alleles are analyzed among the different severity AS patients and the controls. The rs2284336 SNP in JARID1A, the rs16876619 and rs16876657 SNPs in JMY are associated with susceptibility of AS. The rs11062357 SNP in JARID1A, the rs2607142 SNP in JMY and rs10440635 in PTGER4 are related to severity of AS. Haplotype analyses indicate PTGER4 is related to susceptibility to AS; JARID1A and JMY are related to severity of AS.

  17. The Analysis of a Murder, a Case Study

    Science.gov (United States)

    Dinan, Frank J.; Szczepankiewicz, Steven H.; Carnaham, Melinda; Colvin, Michael T.

    2007-01-01

    The analysis of a Murder case study can be used in general chemistry or nonscience major chemistry courses to teach data handling and analysis in a non-laboratory context. This case study will help students to respond more enthusiastically and with more interest to a set of material placed before them related to a real case rather than…

  18. TEACHER BELIEFS: A CASE STUDY

    Institute of Scientific and Technical Information of China (English)

    HuYijie

    2004-01-01

    In recent years ELT has stressed the role which teachers' beliefs play in shaping what they do in the classroom. But so far as teaching English in China is concerned, we lack empirical insight into the relationship between teachers' beliefs and their classroom practice. With specific reference to the use of English in intensive reading classes, by presenting and discussing data from a case study of a non-native college English teacher,this exploratory qualitative classroom research sheds light on the nature of teachers' beliefs held consciously or unconsciously.Their subsequent change and impact on the classroom will also be reported and discussed.

  19. Consumption of fruits and vegetables in relation to the risk of developing acute coronary syndromes; the CARDIO2000 case-control study

    Directory of Open Access Journals (Sweden)

    Chrysohoou Christina

    2003-05-01

    Full Text Available Abstract Background The relation between diet and human health has long been investigated. The aim of this work is to evaluate the association between CHD risk and the consumption of fruit and vegetable, in a large sample of cardiac patients and controls. Methods Stratified sampling from all Greek regions, consisted of 848 (700 males, 58 ± 10 years old and 148 females, 65 ± 9 years old randomly selected patients, admitted to the cardiology clinic for a first event of an acute coronary syndrome (ACS. In addition we selected 1078 frequency paired, by sex-age-region, controls in the same hospitals but without any clinical suspicion of CHD. Using validated food-frequency questionnaires we assessed total diet, including fruit and vegetable intake, on a weekly basis. Multiple logistic regression analysis estimated the relative risk of developing ACS by level of fruits and vegetables intake after taking into account the effect of several potential confounders. Results Data analysis revealed that the benefit of fruit or vegetable consumption increases proportionally by the number of servings consumed (P for trend Conclusions Consumption of fruits and vegetables seems to offer significant protection against CHD.

  20. Being a trainer in the French vocational training system: a case study of job status and working conditions in relation to perceived health.

    Science.gov (United States)

    Delgoulet, Catherine

    2012-01-01

    This communication presents part of an international project focused on the work of trainers from an ergonomics perspective. The objective is to identify in the French vocational training system the various types of job status of trainers and their impact on working conditions and health. In order to explore this issue, we met with 11 trainers, all volunteers, working in the music or human resources sectors. Semi-structured interviews and transcriptions of two weeks of the trainers' professional schedules form the data collected. The analyses show that trainers have various job statuses as trainers and sometimes hold down several jobs at the same time. These working situations create freedom but lack security. With very long daily or weekly working hours, the relationships with trainees and clients are qualified as both very interesting, but also one of the most difficult aspects of the work. The 11 trainers, who considered themselves to be in good health, do however declare infra-pathological disorders, which they often relate to their working conditions. These findings are discussed with regard to the literature and raise issues relating to ergonomic methods in activity analysis and situated action.

  1. Learning with Multimedia Cases: An Evaluation Study

    Science.gov (United States)

    Van Den Berg, Ellen; Jansen, Leanne; Blijleven, Peter

    2004-01-01

    This article is about the relation between case-based learning and transfer in teacher education. Through a design research approach a multimedia case has been developed. The topic of the case is "outdoor activities in science education." The core of the case is a 17 minute video that is supplemented by all kinds of background information. Results…

  2. The Relation between Financial Expenditure for Agriculture( FEA) and Per Capita Net Income of Farmers( PCIF):A Case Study of Jiangsu Province

    Institute of Scientific and Technical Information of China (English)

    Qian; ZHANG

    2014-01-01

    Agricultural development is indispensible to financial support. On the basis of data of the financial expenditure for agriculture( FEA) and per capita net income of farmers( PCIF) of Jiangsu Province in 1990-2012,with the aid of software R,this paper established the linear regression model for the relation between financial expenditure for agriculture and per capita net income of farmers through the function lm. Using the function summary,this paper obtained the summary statistical data,and made diagnostic check of regression model from image command plot and variance analysis table. Finally,it came up with pertinent recommendations including increasing financial expenditure for agriculture,optimizing expenditure structure,and balancing regional development.

  3. PR Students, Teachers Welcome Corporate Case Study Packages.

    Science.gov (United States)

    Broom, Glen M.; Ferguson-De Thorne, Mary Ann

    1978-01-01

    Reports on an actual public relations problem that was used to introduce students to the practice of corporate public relations. Shows both positive and negative reaction to use of the case study in college classes. (RL)

  4. The relation between Arctic sea ice surface elevation and draft: A case study using coincident AUV sonar and airborne scanning laser

    Science.gov (United States)

    Doble, Martin J.; Skourup, Henriette; Wadhams, Peter; Geiger, Cathleen A.

    2011-08-01

    Data are presented from a survey by airborne scanning laser profilometer and an AUV-mounted, upward looking swath sonar in the spring Beaufort Sea. The air-snow (surface elevation) and water-ice (draft) surfaces were mapped at 1 × 1 m resolution over a 300 × 300 m area. Data were separated into level and deformed ice fractions using the surface roughness of the sonar data. The relation (R = d/f) between draft, d, and surface elevation, f, was then examined. Correlation between top and bottom surfaces was essentially zero at full resolution, requiring averaging over patches of at least 11 m diameter to constrain the relation largely because of the significant error (˜15 cm) of the laser instrument. Level ice points were concentrated in two core regions, corresponding to level FY ice and refrozen leads, with variations in R attributed primarily to positive snow thickness variability. Deformed ice displayed a more diffuse "cloud," with draft having a more important role in determining R because of wider deformed features underwater. Averaging over footprints similar to satellite altimeters showed the mean surface elevation (typical of ICESat) to be stable with averaging scale, with R = 3.4 (level) and R = 4.2 (deformed). The "minimum elevation within a footprint" characteristic reported for CryoSat was less stable, significantly overestimating R for level ice (R > 5) and deformed ice (R > 6). The mean draft difference between measurements and isostasy suggests 70 m as an isostatic length scale for level ice. The isostatic scale for deformed ice appears to be longer than accessible with these data (>300 m).

  5. Regional case studies--Africa.

    Science.gov (United States)

    Prentice, Andrew M

    2009-01-01

    Africa is the final continent to be affected by the nutrition transition and, as elsewhere, is characterized by the paradoxical coexistence of malnutrition and obesity. Several features of the obesity epidemic in Africa mirror those in other emerging nations: it penetrates the richer nations and urban areas first with a strong urban- rural gradient; initially it affects the wealthy, but later there is a demographic switch as obesity becomes a condition more associated with poverty, and it shares many of the same drivers related to the increasing affordability of highly refined oils and carbohydrates, and a move away from subsistence farm work and towards sedentary lifestyles. Africa also has some characteristics of the obesity epidemic that stand out from other regions such as: (1) excepting some areas of the Pacific, Africa is probably the only region in which obesity (especially among women) is viewed culturally as a positive and desirable trait, leading to major gender differences in obesity rates in many countries; (2) most of Africa has very low rates of obesity in children, and to date African obesity is mostly an adult syndrome; (3) Africans seem genetically prone to higher rates of diabetes and hypertension in association with obesity than Caucasians, but seem to be relatively protected from dislipidemias; (4) the case-specific deaths and disabilities from diabetes and hypertension in Africa are very high due to the paucity of health services and the strain that the 'double burden' of disease places on health systems.

  6. Shuttle Transportation System Case-Study Development

    Science.gov (United States)

    Ransom, Khadijah

    2012-01-01

    A case-study collection was developed for NASA's Space Shuttle Program. Using lessons learned and documented by NASA KSC engineers, analysts, and contractors, decades of information related to processing and launching the Space Shuttle was gathered into a single database. The goal was to provide educators with an alternative means to teach real-world engineering processes and to enhance critical thinking, decision making, and problem solving skills. Suggested formats were created to assist both external educators and internal NASA employees to develop and contribute their own case-study reports to share with other educators and students. Via group project, class discussion, or open-ended research format, students will be introduced to the unique decision making process related to Shuttle missions and development. Teaching notes, images, and related documents will be made accessible to the public for presentation of Space Shuttle reports. Lessons investigated included the engine cutoff (ECO) sensor anomaly which occurred during mission STS-114. Students will be presented with general mission infom1ation as well as an explanation of ECO sensors. The project will conclude with the design of a website that allows for distribution of information to the public as well as case-study report submissions from other educators online.

  7. Physiologic amputation: a case study.

    Science.gov (United States)

    Long, Jeri; Hall, Virginia

    2014-03-01

    Acute limb ischemia is a complication of severe peripheral arterial disease that can be a threatening limb as well as life. Multiple procedures exist today to help revascularize extremities; however, even with the latest technologies, surgical amputation of the limb may still be necessary. Cryoamputation, or physiologic amputation, is a method used to treat patients who are hemodynamically unstable for the operating room and who are in need of urgent amputation owing to arterial ischemia. This procedure is used in the rare instance where not only a persons' limb is threatened, but also their life. This is a case study regarding one patient who presented to the hospital with limb-threatening ischemia who became hemodynamically unstable owing to the rhabdomyolysis associated with the ischemia of his lower extremity. Cryoamputation was used to stabilize the patient and prevent further deterioration, so that he could safely undergo surgical amputation of the limb without an increase in mortality risk. Cryoamputation must be followed by formal surgical amputation when the patient is hemodynamically stabilized. It is not a limb salvaging, procedure but it is a life-saving procedure. This case study demonstrates the usefulness of the procedure and discusses the technique used for cryoamputation.

  8. Bridging the Performance Gap with Ergonomics: A Case Study

    Science.gov (United States)

    Rethaber, James D.

    2011-01-01

    Faced with increased incidences of work-related strain and sprain injuries and OSHA-recordable injuries, the organization in this case study details how it resolved these performance-related issues. This case study also demonstrates the effectiveness of Thomas Gilbert's (1978) Behavior Engineering Model as a tool for analyzing, defining, and…

  9. Five misunderstandings about Case-study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...

  10. Five misunderstandings about case study research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2004-01-01

    This article examines five common misunderstandings about case-study research: (1) Theoretical knowledge is more valuable than practical knowledge; (2) One cannot generalize from a single case, therefore the single case study cannot contribute to scientific development; (3) The case study is most...

  11. Using Correspondence Analysis in Multiple Case Studies

    NARCIS (Netherlands)

    Kienstra, Natascha; van der Heijden, Peter G.M.

    2015-01-01

    In qualitative research of multiple case studies, Miles and Huberman proposed to summarize the separate cases in a so-called meta-matrix that consists of cases by variables. Yin discusses cross-case synthesis to study this matrix. We propose correspondence analysis (CA) as a useful tool to study thi

  12. Using correspondence analysis in multiple case studies

    NARCIS (Netherlands)

    Kienstra, N.H.H.; van der Heijden, P.G.M.

    2015-01-01

    In qualitative research of multiple case studies, Miles and Huberman proposed to summarize the separate cases in a so-called meta-matrix that consists of cases by variables. Yin discusses cross-case synthesis to study this matrix. We propose correspondence analysis (CA) as a useful tool to study thi

  13. Instilling Service Learning to Undergraduate Business Students: A Case Study Approach to Understanding Business-Related Concepts with the Use of Kiva

    Science.gov (United States)

    Grotrian-Ryan, Sheri; Ryan, Kyle; Jackson, Alan

    2016-01-01

    Higher education continues to place an emphasis on service-learning, specifically within business and management sciences (Kenworthy-U'Ren & Peterson, 2005). A local academic business organization at a small institution chose to embark on a service-learning endeavor. The purpose of this study was for business majors, active in Phi Beta Lambda…

  14. THE MACULAR HOLE AFTER INTRAVITREAL INJECTIONS OF RANIBIZUMAB IN A PATIENT WITH EXUDATIVE AGE-RELATED MACULAR DEGENERATION – A CASE STUDY

    Directory of Open Access Journals (Sweden)

    Magdalena Kal

    2013-11-01

    Full Text Available There are two forms of age-related macular degeneration (AMD, the dry one and the exudative one. The exudative form of AMD can be treated using repeated intravitreal injections of antibodies against vascular endothelial growth factor (VEGF. Optical coherence tomography (OCT of the retina is a standard examination in monitoring patients treated with ranibizumab due to an exudative form of AMD. VEGF plays a key role in the development of choroidal neovascularization in the exudative form of AMD. The subject-matter of our observation was to present the development of the macular hole after treatment of the exudative form of AMD through repeated intravitreal injections of ranibizumab. Ranibizumab is an antibody against VEGF. This substance is registered for the treatment of the exudative form of AMD. Ranibizumab may produce focal sites with traction forces on the surface of the retina during the contraction of the choroidal neovascular membrane. Both of these effects may cause contraction and delamination of the retina causing the macular hole to form.

  15. A Methodology for Cancer Therapeutics by Systems Pharmacology-Based Analysis: A Case Study on Breast Cancer-Related Traditional Chinese Medicines

    Science.gov (United States)

    Li, Yan; Wang, Jinghui; Lin, Feng; Yang, Yinfeng; Chen, Su-Shing

    2017-01-01

    Breast cancer is the most common carcinoma in women. Comprehensive therapy on breast cancer including surgical operation, chemotherapy, radiotherapy, endocrinotherapy, etc. could help, but still has serious side effect and resistance against anticancer drugs. Complementary and alternative medicine (CAM) may avoid these problems, in which traditional Chinese medicine (TCM) has been highlighted. In this section, to analyze the mechanism through which TCM act on breast cancer, we have built a virtual model consisting of the construction of database, oral bioavailability prediction, drug-likeness evaluation, target prediction, network construction. The 20 commonly employed herbs for the treatment of breast cancer were used as a database to carry out research. As a result, 150 ingredient compounds were screened out as active molecules for the herbs, with 33 target proteins predicted. Our analysis indicates that these herbs 1) takes a ‘Jun-Chen-Zuo-Shi” as rule of prescription, 2) which function mainly through perturbing three pathways involving the epidermal growth factor receptor, estrogen receptor, and inflammatory pathways, to 3) display the breast cancer-related anti-estrogen, anti-inflammatory, regulation of cell metabolism and proliferation activities. To sum it up, by providing a novel in silico strategy for investigation of the botanical drugs, this work may be of some help for understanding the action mechanisms of herbal medicines and for discovery of new drugs from plants. PMID:28068355

  16. Explaining the Relationship between Organizational Structure and Dimensions of Learning Organizations (Case study: Education Organization in Boroojerd County and the Related Departments

    Directory of Open Access Journals (Sweden)

    Javad Mehrabi

    2013-04-01

    Full Text Available The present survey has been conducted to explain the relationship between organizational structure and dimensions of learning organizations. It was conducted using descriptive-field method. The statistical population included employees of Education Organization in Borujerd County and the related departments. Sample volume was selected through random sampling method and was equal to 140 persons using Morgan table. Validity of the questionnaire was confirmed through content validity by professors and the clear-sighted. Its reliability was measured using pre-test and calculating Cronbach alpha. Pierson correlation coefficient, Friedman test and bi-nominal test using SPSS software were used for data analysis. Results of Pierson correlation coefficient test show there is a significant and negative relationship between organizational structure and fulfillment degree of learning organizations. This relationship is significant about all dimensions of learning organization. Given to results of Friedman test, the most important dimension of learning organizations is the component of team learning based on the viewpoint of employees of the Education Organization. According to results of bi-nominal test, there is only one variable in the statistical population and that is mental models. Also according to results of correlation coefficient matrix of research variables team learning and shared vision have the highest correlation.

  17. Selling the Internet: A Cultural Studies Approach to Public Relations.

    Science.gov (United States)

    Mickey, Thomas J.

    1998-01-01

    Examines the ideology of Internet public relations. Takes a cultural studies approach to modern public relations, using public relations material as representation. Presents a case study of the MassNetworks Education Partnership, which was set up in 1996 to ensure that the Internet gets into the classroom. (PA)

  18. RELATION OF HYPERTENSION TO DIABETIC NEPHROPATHY IN PATIENTS WITH NON INSULIN DEPENDENT DIABETES MELLITUS-A PAIR MATCHED CASE CONTROL STUDY

    Institute of Scientific and Technical Information of China (English)

    侯旭宏; 王建华; 冯凭

    2002-01-01

    Objective.To assess the role of hypertension and family history of hypertension in the development of nephropathy in patients with non insulin dependent diabetes mellitus (NIDDM). Methods.A retrospective analysis was done on 2 groups of NIDDM patients,one group without proteinuria (urine protein< 300mg/24h,n=106) and the other group with proteinuria (urine protein≥ 500mg/24h,n=106).The 2 groups were matched by age(≤± 3yrs),sex,ethnic and resident place.Some information of these subjects including demographic;history of disease,family history of diseases,lifestyle and behavior style variables was obtained by questionnaire;some variables were measured,including systolic blood pressure (SBP),diastolic blood pressure (DBP),fasting blood glucose (FBG),quantity of protein in 24h urine.Then conditional logistic regression analysis was performed. Results.Some factors,including history of hypertension,longer duration of hypertension,higher levels of the past highest SBP and DBP,were independently associated with the occurrence risk of diabetic nephropathy (DN).Their corresponding odd ratios (OR) with 95% confidence intervals (CI) were 2.00(1.17~3.43),1.25(1.08~1.46),1.38(1.15~1.66),and 1.33(1.09~1.62) respectively,but family history of hypertension was not significantly associated with the development of DN.When the above mentioned relations were respectively adjusted by some possible confounding factors,they still existed. Conclusions.History of hypertension,longer duration of hypertension,higher levels of the past highest SBP and DBP are independent risk factors for DN in Chinese NIDDM patients.

  19. Using Statistical Downscaling to Quantify the GCM-Related Uncertainty in Regional Climate Change Scenarios: A Case Study of Swedish Precipitation

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    There are a number of sources of uncertainty in regional climate change scenarios. When statistical downscaling is used to obtain regional climate change scenarios, the uncertainty may originate from the uncertainties in the global climate models used, the skill of the statistical model, and the forcing scenarios applied to the global climate model. The uncertainty associated with global climate models can be evaluated by examining the differences in the predictors and in the downscaled climate change scenarios based on a set of different global climate models. When standardized global climate model simulations such as the second phase of the Coupled Model Intercomparison Project (CMIP2) are used, the difference in the downscaled variables mainly reflects differences in the climate models and the natural variability in the simulated climates. It is proposed that the spread of the estimates can be taken as a measure of the uncertainty associated with global climate models. The proposed method is applied to the estimation of global-climate-model-related uncertainty in regional precipitation change scenarios in Sweden. Results from statistical downscaling based on 17 global climate models show that there is an overall increase in annual precipitation all over Sweden although a considerable spread of the changes in the precipitation exists. The general increase can be attributed to the increased large-scale precipitation and the enhanced westerly wind. The estimated uncertainty is nearly independent of region. However, there is a seasonal dependence. The estimates for winter show the highest level of confidence, while the estimates for summer show the least.

  20. Hydrological and geochemical processes constraining groundwater salinity in wetland areas related to evaporitic (karst) systems. A case study from Southern Spain

    Science.gov (United States)

    Gil-Márquez, J. M.; Barberá, J. A.; Andreo, B.; Mudarra, M.

    2017-01-01

    Chemical and isotopic evolution of groundwater in an evaporite karst plateau (including wetland areas and saline to hyper-saline springs) located at S Spain was studied. Physicochemical parameters, major ions and stable isotopes were analyzed in rain, brine spring, wetland and leakage water samples, from which the most common mineral saturation indexes were computed and geochemical and isotopic modelling were performed. Results show an apparent relationship between the elevation of brine springs and their water mineralization, indicating that drainage at higher altitude may be associated to gravity-driven flows, since brackish groundwater is isotopically fractionated due to evaporation. On the other hand, the lower altitude springs could drain deeper flows with longer residence time, resulting in highly mineralized and warmer (briny) groundwater. The dissolution of halite and gypsum has proved to be the main geochemical processes, which are favored by the great ionic strength of groundwater. Calcite precipitation occurs in brackish waters draining wetlands, being boosted by common ion effect (when CaSO4 waters are present) and solute concentration caused by evaporation. Modelling results strongly support the hypothesis that most of the selected springs geochemically evolve in a common (S-N) flowpath. The methods used in this research contribute to a better understanding of the hydrogeological processes occurring in the studied evaporitic system, but also in equivalent hydrological environments worldwide.

  1. Towards a multidisciplinary and integrated strategy in the assessment of adverse health effects related to air pollution: The case study of Cracow (Poland) and asthma

    Energy Technology Data Exchange (ETDEWEB)

    Oudinet, Jean-Paul [Centre de Biogeographie - Ecologie FRE 2545 CNRS, Maison de la recherche, Universite Paris - Sorbonne, Paris IV, 28 rue Serpente, 75006 Paris (France)]. E-mail: biogeo@paris4.sorbonne.fr; Meline, Julie [Centre de Biogeographie - Ecologie FRE 2545 CNRS, Maison de la recherche, Universite Paris - Sorbonne, Paris IV, 28 rue Serpente, 75006 Paris (France); Chelmicki, Wojciech [Institute of Geography and Spatial Management, Jagiellonian University, ul. Gronostajowa 7, 30-387 Cracow (Poland); Sanak, Marek [Molecular Biology Laboratory, Department of Internal Medicine, Jagiellonian University, ul. Skawinska 8, 31066 Cracow (Poland); Magdalena, Dutsch-Wicherek [Otolaryngology and Head and Neck Department, Jagiellonian University, ul. Sniadeckich 2, 31501 Cracow (Poland); Besancenot, Jean-Pierre [Climat et sante, Centre universitaire d' epidemiologie de population, Faculte de Medecine, BP 87900, 21079 Dijon Cedex (France); Wicherek, Stanislas [Centre de Biogeographie - Ecologie FRE 2545 CNRS, Maison de la recherche, Universite Paris - Sorbonne, Paris IV, 28 rue Serpente, 75006 Paris (France); Julien-Laferriere, Bertrand [Centre de Biogeographie - Ecologie FRE 2545 CNRS, Maison de la recherche, Universite Paris - Sorbonne, Paris IV, 28 rue Serpente, 75006 Paris (France); Gilg, Jean-Paul [Laboratoire Teleanalyse, Espace et Societe, Centre d' Analyse et de Mathematique Sociales, UMR 8557 CNRS - EHESS, 54, Boulevard Raspail, 75006 Paris (France); Geroyannis, Helene [Laboratoire Teleanalyse, Espace et Societe, Centre d' Analyse et de Mathematique Sociales, UMR 8557 CNRS - EHESS, 54, Boulevard Raspail, 75006 Paris (France); Szczeklik, Andrew [Molecular Biology Laboratory, Department of Internal Medicine, Jagiellonian University, ul. Skawinska 8, 31066 Cracow (Poland); Krzemien, Kazimierz [Institute of Geography and Spatial Management, Jagiellonian University, ul. Gronostajowa 7, 30-387 Cracow (Poland)

    2006-09-15

    Complex interaction between anthropogenic activities, air quality and human health in urban areas, such as in Cracow sustains the need for the development of an interdisciplinary and integrated risk-assessment methodology. In such purpose, we propose a pilot study performed on asthmatics and based on a combined use of a biomarker, such as metallothionein 2A (MT-2A) in the characterization of human exposure to one or a mixture of pollutants and of Geographical Information Systems (G.I.S.) which integrates climatic and urban anthropogenic parameters in the assessment of spatio-temporal dispersion of air pollutants. Considering global incidence of air pollution on asthma and on peripheral blood lymphocytes MT-2A expression should provide a complementary information on biological risks linked to urban anthropogenic activities. Such study would help for the establishment of a sustainable development in urban areas that can maintain the integrity of air quality and preserve human health. - An integrative risk methodology based on both geographic and molecular biological approaches is proposed for the assessment of asthmatics exposure to urban air pollution.

  2. In infectious endocarditis patients mortality is highly related to kidney function at time of diagnosis: a prospective observational cohort study of 231 cases

    DEFF Research Database (Denmark)

    Buchholtz, Kristine; Larsen, Carsten T; Hassager, Christian;

    2009-01-01

    function at the time of admittance. METHODS: In a prospective observational cohort study data from 235 consecutive IE patients were collected at 2 tertiary heart centres in Copenhagen. Kidney function was evaluated as Estimated Endogenous Creatinine Clearance (EECC) calculated at the time of admission.......9%) and Staphylococcus aureus (21.8%). Mean follow-up time was 453 days (SD 350). A total number of 76 patients died (32%), with an in-hospital mortality of 14%, and a post discharge mortality of 18%. In 64.9% EECC was decreased at time of admission, and a highly significant relationship between EECC and mortality...... was demonstrated, Ptime of admission is easily obtained in all IE patients...

  3. Desmin-related myopathy: Report of a rare case

    Directory of Open Access Journals (Sweden)

    Sridhar E

    2005-01-01

    Full Text Available The Protein Surplus Myopathies (PSM are characterized by accumulation of protein aggregates, identifiable ultrastructurally, resulting due to mutations of the encoding genes. Desmin-related myopathies (DRM are a form of PSM characterized by mutations of the desmin gene resulting in the formation of protein aggregates comprising mutant protein desmin and disturbance of the regular desmin intermediate network in the muscle fibers. We describe a rare case of DRM in a 23-year-old man who presented with complaints of difficulty in climbing stairs and running since the age of 5 years. EMG studies revealed a myopathic pattern. Muscle biopsy showed the features of muscular dystrophy with bluish rimmed vacuoles and sarcoplasmic inclusions, which were immunoreactive to desmin. Ultrastructural examination showed sarcoplasmic bodies and granulofilamentous inclusions. Although rare, the possibility of DRM/desminopathy should be considered in the presence of bluish rimmed vacuoles on light microscopy and characteristic ultrastructural inclusions. To the best of our knowledge this is the first case of DRM/desminopathy reported from India.

  4. Recurrent perinatal loss: a case study.

    Science.gov (United States)

    Kavanaugh, K; Robertson, P A

    1999-01-01

    To date, investigators have not demonstrated a clear relationship between a parent's history of prior perinatal losses and intensity of grief response following a subsequent perinatal loss. Examining this relationship for low-income, African-American parents is important because they are a vulnerable population due to the high incidence of perinatal mortality in Blacks and their other life stressors that can impact on grief response and caring needs. The purpose of this case study was to examine the impact of recurrent perinatal loss on a low-income African-American parent. The research design for this study was case report, using interview data collected from a mother who had recently experienced her fourth perinatal loss, which occurred at twenty-five weeks of gestation. Transcripts from two open-ended interviews were analyzed. The theoretical framework used to guide analysis of this case study was Lazarus and Folkman's stress and coping theory. Results demonstrated that the prior perinatal losses did not appear as critical components of the way the mother responded to her most recent loss. Instead, perception of the care she received from healthcare providers and how that care related to her experiences with her one living child who was born at the same gestational age was an important determinant in how she responded to her loss. The results of this case study demonstrate the importance assessing a person's perception of their experience and those factors which contribute to the way they respond.

  5. Nanomaterial Case Studies: Nanoscale Titanium Dioxide ...

    Science.gov (United States)

    This draft document presents two case studies of nanoscale titanium dioxide (nano-TiO2) used (1) to remove arsenic from drinking water and (2) as an active ingredient in topical sunscreen. The draft case studies are organized around a comprehensive environmental assessment approach that combines a product life cycle framework with the risk assessment paradigm. The document does not draw conclusions about potential risks. Rather, the case studies are intended to help identify what needs to be known in order to conduct a comprehensive environmental assessment of the potential risks related to nano-TiO2. This draft document is part of a process that will inform the development of EPA’s research strategy to support nanomaterial risk assessments. The complex properties of various nanomaterials make evaluating them in the abstract or with generalizations difficult if not impossible. Thus, this document focuses on two specific uses of nano-TiO2, as a drinking water treatment and as topical sunscreen. These case studies do not represent completed or even preliminary assessments; rather, they present the structure for identifying and prioritizing research needed to support future assessments.

  6. Where to look for tsunami deposits? A case study from the Santorini related tsunami and the 1956 tsunami at Palaikastro, Crete

    Science.gov (United States)

    Qupty, Nairooz; Synalokis, Costas; MacGillvray, Alexander; Goodman-Tchernov, Beverly

    2016-04-01

    Searching within the shallow offshore zones for preserved tsunamiginic deposits has been demonstrated as a worthwhile and important means to identify and study its tsunami events. For example, research at Caesarea Maritima, Israel, recognized tsunamigenic deposits in shallow (less than 30 m) upper shelf offshore deposits, while the onland signature of the same events were still unidentified. In Palaikastros, Crete, Late Minoan period layers were reported on coastal cliffs, and eye-witness observations described tsunami run-up and inundation following the 1956 Amorgos earthquake. In an effort to find remnant deposits from these tsunami events, four cores were collected offshore. The cores were collected from different marine settings (which include river influence, posidonia rich seafloor, micro-morphological changes, etc.). On-land samples were also collected for comparison. Results from the offshore cores reveal two distinctive anomalous horizons. The deeper and older disturbance is most probably the post-depositional sedimentation just above the Santorini eruption deposit, and the shallower disturbance represents the 1956 AD tsunami event. Interestingly, no sedimentological evidence for the 1956 tsunami event was noticed in the coastal backshore. The sedimentological signatures of the two tsunami events were very different in the cores collected from the varied marine settings. In the cores collected immediately offshore from the river, the 1956 event is marked by what appears to be a massive flood-like deposit, rather than the coarse deposits seen elsewhere. Cores in the area of the posidonia-rich seafloor had the most subtle variations that could only be speculatively associated to the tsunamigenic layers. The Santorini tsunami sedimentological signatures in these cores were not significant. It is possible that the layers were reworked and washed away following their deposition, or rather, affected from stream inflow or sediments turbidation in posidonia

  7. Case Study: A Picture Worth a Thousand Words? Making a Case for Video Case Studies

    Science.gov (United States)

    Pai, Aditi

    2014-01-01

    A picture, they say, is worth a thousand words. If a mere picture is worth a thousand words, how much more are "moving pictures" or videos worth? The author poses this not merely as a rhetorical question, but because she wishes to make a case for using videos in the traditional case study method. She recommends four main approaches of…

  8. Great Balls of Fire: A probabilistic approach to quantify the hazard related to ballistics - A case study at La Fossa volcano, Vulcano Island, Italy

    Science.gov (United States)

    Biass, Sébastien; Falcone, Jean-Luc; Bonadonna, Costanza; Di Traglia, Federico; Pistolesi, Marco; Rosi, Mauro; Lestuzzi, Pierino

    2016-10-01

    We present a probabilistic approach to quantify the hazard posed by volcanic ballistic projectiles (VBP) and their potential impact on the built environment. A model named Great Balls of Fire (GBF) is introduced to describe ballistic trajectories of VBPs accounting for a variable drag coefficient and topography. It relies on input parameters easily identifiable in the field and is designed to model large numbers of VBPs stochastically. Associated functions come with the GBF code to post-process model outputs into a comprehensive probabilistic hazard assessment for VBP impacts. Outcomes include probability maps to exceed given thresholds of kinetic energies at impact, hazard curves and probabilistic isoenergy maps. Probabilities are calculated either on equally-sized pixels or zones of interest. The approach is calibrated, validated and applied to La Fossa volcano, Vulcano Island (Italy). We constructed a generic eruption scenario based on stratigraphic studies and numerical inversions of the 1888-1890 long-lasting Vulcanian cycle of La Fossa. Results suggest a ~ 10- 2% probability of occurrence of VBP impacts with kinetic energies ≤ 104 J at the touristic locality of Porto. In parallel, the vulnerability to roof perforation was estimated by combining field observations and published literature, allowing for a first estimate of the potential impact of VBPs during future Vulcanian eruptions. Results indicate a high physical vulnerability to the VBP hazard, and, consequently, half of the building stock having a ≥ 2.5 × 10- 3% probability of roof perforation.

  9. Soil fungistasis and its relations to soil microbial composition and diversity: a case study of a series of soils with different fungistasis

    Institute of Scientific and Technical Information of China (English)

    WU Minna; ZHANG Huiwen; LI Xinyu; ZHANG Yan; SU Zhencheng; ZHANG Chenggang

    2008-01-01

    Fungistasis is one of the important approaches to control soil-borne plant pathogens. Some hypotheses about the mechanisms for soil fungistasis had been established, which mainly focused on the soil bacterial community composition, structure, diversity as well as function. In this study, the bacterial community composition and diversity of a series of soils treated by autoclaving, which coming from the same original soil sample and showing gradient fungistasis to the target soil-borne pathogen fungi Fusarium graminearum, was investigated by soil bacterial 16S rDNA-PCR (polymerance chain reaction) Cloning, Restriction fragment length polymorphism (RFLP), and sequencing. The results showed that the soil fungistasis capacity was closely correlated with soil bacterial community composition and diversity, i.e., soil fungistasis declined with the decrease of soil bacterial diversity. Meanwhile, the bacterial community composition and structure were significantly different along the gradient of soil fungistasis tested. α-Proteobacteria, β-proteobacteria, Flexibacter and some uncultured soil bacteria were contributed to soil fungistasis in combination with some other special bacteria (Pseudomonas and Acidobacteria) which were know to be key species in suppression of fungal growth.

  10. Hydrochemistry dynamics in remote mountain lakes and its relation to catchment and atmospheric features: the case study of Sabocos Tarn, Pyrenees.

    Science.gov (United States)

    Santolaria, Zoe; Arruebo, Tomas; Urieta, José Santiago; Lanaja, Francisco Javier; Pardo, Alfonso; Matesanz, José; Rodriguez-Casals, Carlos

    2015-01-01

    Increasing the understanding of high mountain lake dynamics is essential to use these remote aquatic ecosystems as proxies of global environmental changes. With this aim, at Sabocos, a Pyrenean cirque glacial lake or tarn, this study shows the main results of a morphological and catchment characterization, along with statistical analyses of its hydrochemical trends and their concomitant driving factors from 2010 to 2013. Dissolved oxygen, water temperature stratification, and its snow and ice cover composition and dynamics have been also investigated. According to morphological analyses, Sabocos can be classified as a medium-large and deep lake, having a circular contour and a long water retention time as compared to Pyrenean glacial lake average values. Sabocos hydrochemistry is mainly determined by very high alkalinity, pH and conductivity levels, and high Ca(2+), Mg(2+), and SO4(2-) content, coming from the easily weatherable limestone-dolomite bedrock. Thus, lake water is well buffered, and therefore, Sabocos tarn is non-sensitive to acidification processes. On the other hand, the main source of K(+), Na(+), and Cl(-) (sea salts) and nutrients (NH4(+), NO3(-), and phosphorous) to lake water appears to be atmospheric deposition. Primary production is phosphorous limited, and due to the N-saturation stage of the poorly developed soils of Sabocos catchment, NO3(-) is the chief component in the total nitrogen pool. External temperature seems to be the major driver regulating lake productivity, since warm temperatures boot primary production. Although precipitation might also play an important role in lake dynamics, especially regarding to those parameters influenced by the weathering of the bedrock, its influence cannot be easily assessed due to the seasonal isolation produced by the ice cover. Also, as occurs in the whole Pyrenean lake district, chemical composition of bulk deposition is highly variable due to the contribution of air masses with different origin.

  11. Regional assessment of cadmium pollution in agricultural lands and the potential health risk related to intensive mining activities:A case study in Chenzhou City, China

    Institute of Scientific and Technical Information of China (English)

    ZHAI Limei; LIAO Xiaoyong; CHEN Tongbin; YAN Xiulan; XIE Hua; WU Bin; WANG Lixia

    2008-01-01

    The purpose of this study was to assess the extent of cadmium (Cd) contamination in agricultural soil and its potential risk for people.Soils,rice,and vegetables from Chenzhou City,Southern China were sampled and analyzed.In the surface soils.the 95% confidence interval for the mean concentration of Cd varied between 2.72 and 4.83 mg/kg (P<0.05) in the survey, with a geometric mean concentration of 1.45 mg/kg.Based on the GIS map,two hot spot areas of Cd in agricultural soils with high Cd concentrations were identified to be located around the Shizhuyuan,Jinshiling,and Yaogangxian mines,and the Baoshan and Huangshaping mines,in the center of the city.About 60% of the total investigated area, where the agricultural soil Cd concentration iS above 1 mg/kg, is distributed in a central belt across the region.The critical distances, at which the soil Cd concentration were increased by the mining activities, from the mines of the soils were 23 km for the Baoshan mine,46 km for the Huangshaping mine,and 63 km for the Shizhuyuan mine,respectively.These are distances calculated from models.The Cd concentrations in rice samples ranged from 0.01 to 4.43 mg/kg and the mean dietary Cd intake from rice for an adult was 191 μg/d.Results of risk indexes showed that soil Cd concentrations possessed risks to local residents whose intake of Cd from rice and vegetables grown in soils in the vicinity of the mine was 596 μg/d.

  12. KAIZEN – A case study

    Directory of Open Access Journals (Sweden)

    Manjunath Shettar

    2015-05-01

    Full Text Available The ultimate objective of manufacturing industries is to increase productivity with high quality. At present, many manufacturing companies are facing problems such as high quality rejection, high inventories, high lead time, high costs of production, and inability to cope with customer orders. By implementing and practicing the lean production system many problems can be solved without employing high-tech and high-touch approaches but by involving people on the shop floor in Kaizen activities. Kaizen is one of the powerful tools of lean manufacturing. Kaizen refers to continuous improvement in performance, cost and quality. Kaizen ensures that manufacturing processes become leaner and fitter, but eliminate waste (problem where value is added. The main objective of this paper is to provide a background on kaizen, present an overview of kaizen concepts that are used to transform a company into a high performing lean enterprise. A case study of implementation of Kaizen‟s has been discussed.

  13. STS Case Study Development Support

    Science.gov (United States)

    Rosa de Jesus, Dan A.; Johnson, Grace K.

    2013-01-01

    The Shuttle Case Study Collection (SCSC) has been developed using lessons learned documented by NASA engineers, analysts, and contractors. The SCSC provides educators with a new tool to teach real-world engineering processes with the goal of providing unique educational materials that enhance critical thinking, decision-making and problem-solving skills. During this third phase of the project, responsibilities included: the revision of the Hyper Text Markup Language (HTML) source code to ensure all pages follow World Wide Web Consortium (W3C) standards, and the addition and edition of website content, including text, documents, and images. Basic HTML knowledge was required, as was basic knowledge of photo editing software, and training to learn how to use NASA's Content Management System for website design. The outcome of this project was its release to the public.

  14. Using teaching case studies for management research

    OpenAIRE

    Ambrosini, Veronique; Bowman, Cliff; Collier, Nardine

    2010-01-01

    Teaching case studies are widely deployed in business schools. They are contextually rich in detail, and students learn by applying and adapting theoretical concepts to specific business situations described in the case. This article proposes a new way to use teaching case studies, as research materials for academics. The article addresses three questions: (1) Can teaching cases be used as an alternative to field research? (2) When can teaching case studies be used as second...

  15. Value of case studies in disaster assessment?

    Science.gov (United States)

    Grynszpan, Delphine; Murray, Virginia; Llosa, Silvia

    2011-06-01

    Case studies can be useful in assessing and learning lessons from emergency situations. In this paper, different uses for disaster case studies, are explored with identification of potential pitfalls that should be avoided. In addition, ways to improve the rigor and significance of case studies are suggested. Case studies can be used as examples or as a research tool. If conducted properly, they can provide robust and compelling results. It is argued that sharing a common guide to conducting and writing case studies among all disaster risk reduction professionals could improve the quality of case study reports and thereby strengthen their value in advancing the prevention, preparedness, and management of disasters and emergencies.

  16. Case study on printed matter

    DEFF Research Database (Denmark)

    Introduction Existing product Life Cycle Assessments (LCA’s) on offset printed matter all point at paper as the overall dominating contributor to the impacts from the life-cycle of this category of products. This dominating role of paper is primarily founded in the energy-related impact categories...... include these chemical-related impact categories by making use of some of the newest knowledge about emissions from the production at the printing industry combined with knowledge about the composition of the printing materials used during the production of offset printed matter. This paper is based...... on the dissertation “Assessment of chemical emissions in life cycle impact assessment” (Larsen 2004) and the paper “Life-cycle assessment of offset printed matter with EDIP97 – how important are emissions of chemicals? “ (Larsen et al. 2009). Goal and scope The goal of the study is to identify the distribution...

  17. Do consanguineous parents of a child affected by an autosomal recessive disease have more DNA identical-by-descent than similarly-related parents with healthy offspring? Design of a case-control study

    Directory of Open Access Journals (Sweden)

    Cornel Martina C

    2010-07-01

    Full Text Available Abstract Background The offspring of consanguineous relations have an increased risk of congenital/genetic disorders and early mortality. Consanguineous couples and their offspring account for approximately 10% of the global population. The increased risk for congenital/genetic disorders is most marked for autosomal recessive disorders and depends on the degree of relatedness of the parents. For children of first cousins the increased risk is 2-4%. For individual couples, however, the extra risk can vary from zero to 25% or higher, with only a minority of these couples having an increased risk of at least 25%. It is currently not possible to differentiate between high-and low-risk couples. The quantity of DNA identical-by-descent between couples with the same degree of relatedness shows a remarkable variation. Here we hypothesize that consanguineous partners with children affected by an autosomal recessive disease have more DNA identical-by-descent than similarly-related partners who have only healthy children. The aim of the study is thus to establish whether the amount of DNA identical-by-descent in consanguineous parents of children with an autosomal recessive disease is indeed different from its proportion in consanguineous parents who have healthy children only. Methods/Design This project is designed as a case-control study. Cases are defined as consanguineous couples with one or more children with an autosomal recessive disorder and controls as consanguineous couples with at least three healthy children and no affected child. We aim to include 100 case couples and 100 control couples. Control couples are matched by restricting the search to the same family, clan or ethnic origin as the case couple. Genome-wide SNP arrays will be used to test our hypothesis. Discussion This study contains a new approach to risk assessment in consanguineous couples. There is no previous study on the amount of DNA identical-by-descent in consanguineous

  18. Higher Education: Two Public Relations Case Studies.

    Science.gov (United States)

    Yarrington, Roger

    1983-01-01

    Traces the development and implementation of an information program to combat proposed cuts in student financial aid and a more general program to generate overall support for higher education. (Available from Communication Research Associates, Inc., 7100 Baltimore Blvd., Suite 500, College Park, MD 20740; sc $7.50.) (PD)

  19. EU external relations law : text, cases and materials

    NARCIS (Netherlands)

    Van Vooren, Bart; Wessel, Ramses A.

    2014-01-01

    This major new textbook for students in European law uses a text, cases and materials approach to explore the law, politics, policy and practice of EU external relations, and navigates the complex questions at the interface of these areas. The subject is explored by explaining major constitutional p

  20. Case Study: The Chemistry of Cocaine

    Science.gov (United States)

    Dewprashad, Brahmadeo

    2011-01-01

    This column provides original articles on innovations in case study teaching, assessment of the method, as well as case studies with teaching notes. This month's case study focuses on the chemistry of cocaine to teach a number of core concepts in organic chemistry. It also requires that students read and analyze an original research paper on…

  1. Writing case studies in information systems research

    NARCIS (Netherlands)

    van der Blonk, H.C.

    2003-01-01

    Case study research can be reported in different ways. This paper explores the various ways in which researchers may choose to write down their case studies and then introduces a subsequent typology of writing case studies. The typology is based on a 2 x 2 matrix, resulting in four forms of writing

  2. Concentrated photovoltaics, a case study

    Directory of Open Access Journals (Sweden)

    Antonini Piergiorgio

    2014-01-01

    Full Text Available Concentrated Photovoltaics (CPV, once a niche technology, has now reached the maturity and reliability for large scale power generation. Especially in regions where temperatures are very high, the use of high efficiency triple junction solar cells with concentrating optics allows stable energy yield. Thus CPV can be seen as complementary and not in concurrence with silicon photovoltaics. The state of the art, the advantages and limitations of this technology will be shown. Among the main advantages of CPV is the possibility of a much higher energy supply, when compared to silicon photovoltaics, both comparing CPV and silicon with same area or the same installed power. The use of recycled and recyclable materials allows a more environmentally friendly production. The possibility to couple CPV with desalination facilities, energy storage will be analysed. As an example a case study of a CPV installation in Northern Italy is discussed. Here the use of mature technologies, derived from automotive and lighting sectors resulted in a simple and efficient module.

  3. Concentrated photovoltaics, a case study

    Science.gov (United States)

    Antonini, Piergiorgio; Centro, Sandro; Golfetto, Stelvio; Saccà, Alessandro

    2014-12-01

    Concentrated Photovoltaics (CPV), once a niche technology, has now reached the maturity and reliability for large scale power generation. Especially in regions where temperatures are very high, the use of high efficiency triple junction solar cells with concentrating optics allows stable energy yield. Thus CPV can be seen as complementary and not in concurrence with silicon photovoltaics. The state of the art, the advantages and limitations of this technology will be shown. Among the main advantages of CPV is the possibility of a much higher energy supply, when compared to silicon photovoltaics, both comparing CPV and silicon with same area or the same installed power. The use of recycled and recyclable materials allows a more environmentally friendly production. The possibility to couple CPV with desalination facilities, energy storage will be analysed. As an example a case study of a CPV installation in Northern Italy is discussed. Here the use of mature technologies, derived from automotive and lighting sectors resulted in a simple and efficient module.

  4. Location of gliomas in relation to mobile telephone use: a case-case and case-specular analysis

    DEFF Research Database (Denmark)

    Larjavaara, Suvi; Schüz, Joachim; Swerdlow, Anthony;

    2011-01-01

    approaches: In a case-case analysis, tumor locations were compared with varying exposure levels; in a case-specular analysis, a hypothetical reference location was assigned for each glioma, and the distances from the actual and specular locations to the handset were compared. The study included 888 gliomas......The energy absorbed from the radio-frequency fields of mobile telephones depends strongly on distance from the source. The authors' objective in this study was to evaluate whether gliomas occur preferentially in the areas of the brain having the highest radio-frequency exposure. The authors used 2...... from 7 European countries (2000-2004), with tumor midpoints defined on a 3-dimensional grid based on radiologic images. The case-case analyses were carried out using unconditional logistic regression, whereas in the case-specular analysis, conditional logistic regression was used. In the case-case...

  5. Benchmarking Alumni Relations in Community Colleges: Findings from a 2015 CASE Survey. CASE White Paper

    Science.gov (United States)

    Paradise, Andrew

    2016-01-01

    Building on the inaugural survey conducted three years prior, the 2015 CASE Community College Alumni Relations survey collected additional insightful data on staffing, structure, communications, engagement, and fundraising. This white paper features key data on alumni relations programs at community colleges across the United States. The paper…

  6. Benchmarking Alumni Relations in Community Colleges: Findings from a 2012 CASE Survey. CASE White Paper

    Science.gov (United States)

    Paradise, Andrew; Heaton, Paul

    2013-01-01

    In 2011, CASE founded the Center for Community College Advancement to provide training and resources to help community colleges build and sustain effective fundraising, alumni relations and communications and marketing programs. This white paper summarizes the results of a groundbreaking survey on alumni relations programs at community colleges…

  7. Work-Related Upper Limb Disorders: A Case Report

    Directory of Open Access Journals (Sweden)

    Zlatka Borisova Stoyneva

    2015-03-01

    Full Text Available In this study the complex interrelationship between physical factors, job stress, lifestyle and genetic factors on symptoms of work-related musculoskeletal disorders of the upper limbs is demonstrated by a case report and discussion of the literature. A 58 year old woman with long lasting complaints of the upper limbs with increasing intensity and duration, generalisation, combined with skin thickness, Raynaud’s phenomenon, joint disorders, arterial and pulmonary hypertension, metabolic lipid dysfunctions is presented. Occupational history proves continuous duration of service at a job with occupational physical static load with numerous repetitive monotonous systematic motions of fingers and hands as a weaver of Persian rugs followed by work at an automated loom and variable labour activities. Though the complaints dated since the time she was a manual weaver, the manifestations of generalized joint degenerative changes, system sclerosis with Raynaud’s phenomenon with similar upper extremities signs and symptoms discount upper limbs musculoskeletal disorder as caused only or mainly by occupational risk factors. The main principles and criteria for occupational diagnosis of musculoskeletal upper limb disorders and legislative requirements for their reglamentation are discussed.

  8. Using the Case Study Method in Teaching College Physics

    Science.gov (United States)

    Burko, Lior M.

    2016-01-01

    The case study teaching method has a long history (starting at least with Socrates) and wide current use in business schools, medical schools, law schools, and a variety of other disciplines. However, relatively little use is made of it in the physical sciences, specifically in physics or astronomy. The case study method should be considered by…

  9. A Case of Capgras Syndrome Related to Hypothyroidism.

    Science.gov (United States)

    Hines, Aisha; Stewart, Jonathan T; Catalano, Glenn

    2015-11-01

    Hypothyroidism is commonly associated with a variety of psychiatric conditions, most commonly depression and cognitive impairment, but up to 5% to 15% of symptomatically hypothyroid patients may develop a nonaffective psychosis, classically referred to as "myxedema madness." We report the case of a woman who developed Capgras syndrome in the context of hypothyroidism, and whose psychosis rapidly resolved with levothyroxine supplementation. To date, very few cases of Capgras syndrome related to hypothyroidism have been reported. The pathophysiology of this condition remains unclear but it may be related to global cerebral hypometabolism or possibly to increased cerebral dopamine. Given the robust response of "myxedema madness" to thyroid replacement, psychiatrists should remain vigilant for covert hypothyroidism in patients with psychosis and atypical histories or presentations.

  10. Nanomaterial Case Studies: Nanoscale Titanium Dioxide in ...

    Science.gov (United States)

    EPA announced the availability of the final report, Nanomaterial Case Studies: Nanoscale Titanium Dioxide in Water Treatment and in Topical Sunscreen. This report is a starting point to determine what is known and what needs to be known about selected nanomaterials as part of a process to identify and prioritize research to inform future assessments of the potential ecological and health implications of these materials. Two specific applications of nanoscale titanium dioxide (nano-TiO2) are considered: (1) as an agent for removing arsenic from drinking water; and (2) as an active ingredient in topical sunscreen. These case studies are organized around a comprehensive environmental assessment (CEA) framework that combines a product life cycle perspective with the risk assessment paradigm. They are intended to help identify what may need to be known in order to conduct a comprehensive environmental assessment of the potential risks related to nano-TiO2. These “case studies” do not represent completed or even preliminary assessments, nor are they intended to serve as a basis for risk management decisions in the near term on these specific uses of nano TiO2. Rather, the intent is to use this document in developing the scientific and technical information needed for future assessment efforts.

  11. Transanal rectopexy - twelve case studies

    Directory of Open Access Journals (Sweden)

    Rubens Henrique Oleques Fernandes

    2012-06-01

    Full Text Available OBJECTIVES: This study analyzed the results of transanal rectopexy and showed the benefits of this surgical technique. METHOD: Twelve patients were submitted to rectopexy between 1997 and 2011. The surgical technique used was transanal rectopexy, where the mesorectum was fixed to the sacrum with nonabsorbable suture. Three patients had been submitted to previous surgery, two by the Delorme technique and one by the Thiersch technique. RESULTS: Postoperative hospital stay ranged from 1 to 4 days. One patient (8.3% had intraoperative hematoma, which was treated with local compression and antibiotics. One patient (8.3% had residual mucosal prolapse, which was resected. Prolapse recurrence was seen in one case (8.3%. Improved incontinence occurred in 75% of patients and one patient reported obstructed evacuation in the first month after surgery. No death occurred. CONCLUSION: Transanal rectopexy is a simple, low cost technique, which has shown good efficacy in rectal prolapse control.OBJETIVO: O presente estudo analisou os resultados da retopexia pela via transanal e expôs os benefícios desta técnica cirúrgica. MÉTODO: Doze pacientes com prolapso foram operados no período de 1997 a 2011. A técnica cirúrgica usada foi a retopexia transanal, onde o mesorreto foi fixado ao sacro com fio inabsorvível. Três pacientes tinham cirurgia prévia, dois pela técnica de Delorme e um pela técnica de Thiersch. RESULTADOS: A permanência hospitalar pós-operatória variou de 1- 4 dias. Uma paciente (8,3% apresentou hematoma transoperatório que foi tratado com compressão local e antibioticoterapia. Um paciente apresentou prolapso mucoso residual (8,3%, que foi ressecado. Houve recidiva da procidência em um caso (8,3%. A melhora da incontinência ocorreu em 75% dos pacientes e uma paciente apresentou bloqueio evacuatório no primeiro mês após a cirurgia. Não houve mortalidade entre os pacientes operados. CONCLUSÃO: A retopexia transanal é uma t

  12. [Boxing-related cranial injury in children: a case report].

    Science.gov (United States)

    Timsit, S; Rougeau, T; Grevent, D; Chéron, G

    2012-11-01

    No pediatric recommendations exist in France on the exercise of boxing by children and adolescents despite the risk of traumatic injury, sometimes serious. We report the case of a 15-year-old boy who participated in amateur boxing and had a subdural hematoma. Brain injuries and concussions are frequent and multiple. Severity is not always correlated with the intensity of the blows. There are age-related features. Several international medical organizations oppose boxing for children and adolescents.

  13. Relational Constraint Driven Test Case Synthesis for Web Applications

    Directory of Open Access Journals (Sweden)

    Xiang Fu

    2010-09-01

    Full Text Available This paper proposes a relational constraint driven technique that synthesizes test cases automatically for web applications. Using a static analysis, servlets can be modeled as relational transducers, which manipulate backend databases. We present a synthesis algorithm that generates a sequence of HTTP requests for simulating a user session. The algorithm relies on backward symbolic image computation for reaching a certain database state, given a code coverage objective. With a slight adaptation, the technique can be used for discovering workflow attacks on web applications.

  14. Bisphosphonate related osteonecrosis of the jaws: report of two cases

    Energy Technology Data Exchange (ETDEWEB)

    Han, Jin Woo [College of Dentistry, Gangneung Wonju National University, Gangneung (Korea, Republic of)

    2011-09-15

    Bisphosphonates are compounds used to treat osteoporosis and malignant bone metastasis. Despite the benefits related to the use of these medications, osteonecrosis of the jaws is a significant complication in a subset of patients receiving these drugs. This complication occurs either spontaneously or after a simple dento-alveolar surgery. Recently there were two patients who showed the features of bisphosphonate related osteonecrosis of the jaws (BRONJ) in Gangneung Wonju National University Dental Hospital. The patients revealed the clinical and radiological features of classical osteomyelitis. This report presents two cases of BRONJ which were examined by plain radiography and computed tomography.

  15. Planetary Aeronomy and Related Studies

    Science.gov (United States)

    Hunten, D. M.; Bougher, S. W.; Sprague, A. L.

    1997-01-01

    Mercury atmosphere - Sprague and Hunten, in collaboration with Katharina Lodders of Washington University, proposed, mainly on cosmochemical grounds, that S atoms are an important constituent of the atmosphere (30 times more abundant than sodium). This paper has appeared in Icarus. We also suggest that condensed sulfur is an excellent candidate for the radar-bright polar caps, more plausible than water ice because the latter is only barely stable even in permanently-shadowed craters. The best prospect for detection of the vapor is through its resonance lines, a triplet near 1814 A. Mercury is too close to the Sun to be observed by any existing space telescope, but there is some prospect that the search could be made from a Shuttle-based spectrograph such as Lyle Broadfoot's USTAR. Sprague and Hunten have completed an elaborate data analysis of over 100 measurements of the Na D lines, obtained with the 61-inch telescope and our echelle spectrograph. Full account has been taken of the radiative-transfer problem that arises because the Na atmosphere is not optically thin. The output of this code is used in another program that makes an elaborate inverse interpolation in two angles and optical depth and computes the effect of the seeing (always bad for Mercury). The seeing is determined by fitting cuts across a computed image to part of the spectrum adjacent to the sodium lines, and typically ranges from slightly less than 4 arcsec to worse than 6 (diameter at l/e of a Gaussian). The final result is a list of Na abundances, with some information on spatial distribution. One particularly interesting result of further analysis is a strong abundance maximum in the morning relative to the afternoon, confirming an earlier result for potassium, based on much fewer measurements. The analysis are completed during the extension of the present grant. This work depends heavily on the Hapke parameters used to estimate the reflectance of Mercury's surface. The paper by Domingue et

  16. Drive Electric Vermont Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Fred [Energetics Incorporated, Columbia, MD (United States); Roberts, Dave [Vermont Energy Investment Corporation (VEIC), Burlington, VT (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States); White, Sera [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    Currently in the United States, the heavy majority of plug-in electric vehicle (PEV) sales have been in highly conducive, selected, metropolitan areas; opposed to more broad distribution across the country. The U.S. Department of Energy’s EV Everywhere Grand Challenge is looking carefully at the barriers and opportunities that exist to enable small and midsize communities to partake in the PEV market and benefit from the economic and environmental advantages of PEVs. In order to gain insight into these challenges and barriers, DOE selected a success story (i.e., Drive Electric Vermont) as the subject of this case study, as the state of Vermont is tied with Detroit, Michigan in having the highest percentage of 2014 (most recent complete data) PEV registrations for cold weather U.S. cities and has seen more than a sixfold increase in charging stations over the last three years. The overall objective of this case study was to use the lessons learned from Drive Electric Vermont to determine what activities are most effective at encouraging acquisitions of PEVs and deployment of charging infrastructure in small to midsize communities, prioritizing and sequencing their implementation, identifying robust means for extrapolation, and applying this understanding to other small to midsize communities across the nation. The Drive Electric Vermont Program was formed in 2012 with a goal of increasing the use of electrified transportation in Vermont through policy development, education and outreach, and infrastructure development. The Drive Electric Vermont Program can be broadly broken into four components: (1) strategic planning/leadership, (2) stakeholder/partnership development, (3) education and outreach, and (4) incentives. The early phases of the program focused heavily on strategic planning, and stakeholder and partnership development, followed by a transition to education and outreach activities, charging infrastructure development, and grant and incentive programs

  17. Drive Electric Vermont Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Fred [Energetics Incorporated, Columbia, MD (United States); Roberts, Dave [Vermont Energy Investment Corporation (VEIC), Burlington, VT (United States); Francfort, Jim [Idaho National Lab. (INL), Idaho Falls, ID (United States); White, Sera [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-03-01

    Currently in the United States, the heavy majority of plug-in electric vehicle (PEV) sales have been in highly conducive, selected, metropolitan areas; opposed to more broad distribution across the country. The U.S. Department of Energy’s EV Everywhere Grand Challenge is looking carefully at the barriers and opportunities that exist to enable small and midsize communities to partake in the PEV market and benefit from the economic and environmental advantages of PEVs. In order to gain insight into these challenges and barriers, DOE selected a success story (i.e., Drive Electric Vermont) as the subject of this case study, as the state of Vermont is tied with Detroit, Michigan in having the highest percentage of 2014 (most recent complete data) PEV registrations for cold weather U.S. cities and has seen more than a sixfold increase in charging stations over the last three years. The overall objective of this case study was to use the lessons learned from Drive Electric Vermont to determine what activities are most effective at encouraging acquisitions of PEVs and deployment of charging infrastructure in small to midsize communities, prioritizing and sequencing their implementation, identifying robust means for extrapolation, and applying this understanding to other small to midsize communities across the nation. The Drive Electric Vermont Program was formed in 2012 with a goal of increasing the use of electrified transportation in Vermont through policy development, education and outreach, and infrastructure development. The Drive Electric Vermont Program can be broadly broken into four components: (1) strategic planning/leadership, (2) stakeholder/partnership development, (3) education and outreach, and (4) incentives. The early phases of the program focused heavily on strategic planning, and stakeholder and partnership development, followed by a transition to education and outreach activities, charging infrastructure development, and grant and incentive programs

  18. Relation between aftershock parameters and geodetic slip models: Case study of the 2010 Mw8.8 Maule (Chile) and the 2011 Mw9.0 Tohoku-oki (Japan) earthquakes

    Science.gov (United States)

    Zakharova, Olga; Hainzl, Sebastian; Lange, Dietrich; Enescu, Bogdan

    2016-04-01

    The distribution of local stresses, which represents as well crustal heterogeneity, is the main factor for aftershock triggering. Though neither local stresses nor crustal heterogeneity are known in detail, some information of their distribution is implicitly represented by slip and coupling values on the mainshock fault interface. Taking these two concepts as the main assumptions, we perform a comprehensive analysis of the relation between aftershock characteristics and geodetic measurements on the mainshock fault interface. As a case study we select two megathrust events, the 2010 Mw8.8 Maule (Chile) and the 2011 Mw9.0 Tohoku-oki (Japan), due to the availability of rich aftershock data as well as of geodetic inversion models. To investigate the dependency between these data sets we firstly estimated the aftershock parameter distribution, using a modified ETAS model, which allows to take into account the mainshock rupture extension. Secondly we calculate the correlation between aftershock parameters and coseismic/postseismic slip and interseismic coupling. We find: (1) aftershocks tend to occur in the areas of high coseismic slip gradient, afterslip and interseismic coupling; (2) aftershock seismic moment is released preferentially in regions of large coseismic slip, coseismic slip gradient and interseismically locked areas; (3) anomalous aftershock parameters occur in the areas of reactivated fault systems. Moreover, we show that modified ETAS model outperforms the classical one in the cases when the mainshock rupture extension cannot be neglected and represented as a point source. One of the main restriction in the presented analysis is related to the large uncertainties of the inversion models, which limit the significance of our results.

  19. Weakly linear systems of fuzzy relation inequalities: The heterogeneous case

    CERN Document Server

    Ignjatović, Jelena; Damljanović, Nada; Jančić, Ivana

    2011-01-01

    New types of systems of fuzzy relation inequalities and equations, called weakly linear, have been recently introduced in [J. Ignjatovi\\'c, M. \\'Ciri\\'c, S. Bogdanovi\\'c, On the greatest solutions to weakly linear systems of fuzzy relation inequalities and equations, Fuzzy Sets and Systems 161 (2010) 3081--3113.]. The mentioned paper dealt with homogeneous weakly linear systems, composed of fuzzy relations on a single set, and a method for computing their greatest solutions has been provided. This method is based on the computing of the greatest post-fixed point, contained in a given fuzzy relation, of an isotone function on the lattice of fuzzy relations. Here we adapt this method for computing the greatest solutions of heterogeneous weakly linear systems, where the unknown fuzzy relation relates two possibly different sets. We also introduce and study quotient fuzzy relational systems and establish relationships between solutions to heterogeneous and homogeneous weakly linear systems. Besides, we point out ...

  20. Roadmaster Roading Contractors Case Study

    Directory of Open Access Journals (Sweden)

    Hazel Taylor

    1999-01-01

    Full Text Available Systems analysis students seldom experience the practical difficulties of the initial investigation into a client’s requirements. They get little chance to practice the skills they need to investigate complex and confused problem situations, or to appreciate the wider organizational issues that can impact on a situation. This teaching case is designed to give students the opportunity to practice and apply investigation skills and to challenge them to consider the wider work environment when considering possible solutions to a problem situation. The case is conducted as a role-play, with students acting as systems analysts and teaching staff role-playing the clients. The students develop a report analyzing the client’s situation based on the issues that arise during the interviews. Feed-back sessions focus on discussing how well the students applied various interviewing strategies previously covered in lectures, and on the wider organizational problems that could impact proposed information system solutions.

  1. Health-related quality of life in adolescents with screening-detected celiac disease, before and one year after diagnosis and initiation of gluten-free diet, a prospective nested case-referent study

    Directory of Open Access Journals (Sweden)

    Nordyke Katrina

    2013-02-01

    Full Text Available Abstract Background Celiac disease (CD is a chronic disorder in genetically predisposed individuals in which a small intestinal immune-mediated enteropathy is precipitated by dietary gluten. It can be difficult to diagnose because signs and symptoms may be absent, subtle, or not recognized as CD related and therefore not prompt testing within routine clinical practice. Thus, most people with CD are undiagnosed and a public health intervention, which involves screening the general population, is an option to find those with unrecognized CD. However, how these screening-detected individuals experience the diagnosis and treatment (gluten-free diet is not fully understood. The aim of this study is to investigate the health-related quality of life (HRQoL of adolescents with screening-detected CD before and one year after diagnosis and treatment. Methods A prospective nested case-referent study was done involving Swedish adolescents who had participated in a CD screening study when they were in the sixth grade and about 12 years old. Screening-detected adolescents (n = 103 and referents without CD who participated in the same screening (n = 483 answered questionnaires at the time of the screening and approximately one year after the screening-detected adolescents had received their diagnosis that included the EQ-5D instrument used to measure health status and report HRQoL. Results The HRQoL for the adolescents with screening-detected CD is similar to the referents, both before and one year after diagnosis and initiation of the gluten-free diet, except in the dimension of pain at follow-up. In the pain dimension at follow-up, fewer cases reported problems than referents (12.6% and 21.9% respectively, Adjusted OR 0.50, 95% CI 0.27-0.94. However, a sex stratified analysis revealed that the significant difference was for boys at follow-up, where fewer screening-detected boys reported problems (4.3% compared to referent boys (18.8% (Adjusted OR 0

  2. Associative visual agnosia: a case study.

    Science.gov (United States)

    Charnallet, A; Carbonnel, S; David, D; Moreaud, O

    2008-01-01

    We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study, an alternative account in the framework of (non abstractive) episodic models of memory.

  3. Study on Case Teaching of Financial Management

    Science.gov (United States)

    Che, Zhenghong; Che, Zhengmei

    2011-01-01

    Case teaching is an efficient teaching method of management. It plays an important role to enhance the students' ability to practice the theory. However, case teaching of financial management has not achieved the expected results. The paper aims to study the importance, characteristics and corresponding methods of case teaching method of financial…

  4. Associative Visual Agnosia: A Case Study

    OpenAIRE

    A. Charnallet; S. Carbonnel; David, D.; Moreaud, O.

    2008-01-01

    We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study [1], an alternative account in the framework of (non abstractive) episodic models of memory [4].

  5. Controlling the Didactic Relation: A Case in Process Engineering Education

    Science.gov (United States)

    Jaako, Juha

    2014-01-01

    A case study was conducted during 1994-2013 on several groups of process engineering students to see what was needed to transform a single course from a teacher-centred to a student-centred learning environment (SCLE). Development work was done incrementally, using Herbart's didactic triangle as a theoretical framework. The effects of the…

  6. Novice Teachers' Case Dilemmas: Surprising Perspectives Related to Diversity.

    Science.gov (United States)

    Mastrilli, Thomas; Sardo-Brown, Deborah; Hinson, Stephanie

    This study described novice teachers' case dilemmas, analyzing them for assumptions made by teachers about teaching and learning as well as for solutions to the dilemmas. Twenty-one of the thirty-six dilemmas emphasized either minority students, students of low socioeconomic status, or students from single-parent households. Among the issues…

  7. Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1 and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study

    Directory of Open Access Journals (Sweden)

    Overvad Kim

    2009-11-01

    Full Text Available Abstract Background The xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1 and Breast Cancer Resistance Protein (BCRP/ABCG2 may restrict intestinal absorption of various carcinogens, including heterocyclic amines (HCA and polycyclic aromatic hydrocarbons (PAH. Cyclooxygenase-2 (COX-2 derived prostaglandins promote gastrointestinal carcinogenesis, affecting angiogenesis, apoptosis, and invasiveness. The aim of this study was to investigate if polymorphisms in these genes were associated with risk of colorectal cancer (CRC, and to investigate possible interactions with lifestyle factors such as smoking, meat consumption, and NSAID use. Methods The following polymorphisms were analyzed; a synonymous MDR1 C3435T (rs1045642 in exon26, G-rs3789243-A in intron3, the functional BCRP C421A (rs2231142, the two COX-2 A-1195G (rs689466 and G-765C (rs20417 in the promoter region, and the COX-2 T8473C (rs5275 polymorphisms in the 3'-untranslated region. The polymorphisms were assessed together with lifestyle factors in a nested case-cohort study of 359 cases and a random cohort sample of 765 participants from the Danish prospective Diet, Cancer and Health study. Results Carriers of the variant allele of MDR1 intron 3 polymorphism were at 1.52-fold higher risk of CRC than homozygous wild type allele carriers (Incidence rate ratio (IRR = 1.52, 95% Confidence Interval (CI: 1.12-2.06. Carriers of the variant allele of MDR1 C3435T exon 26 had a lower risk of CRC than homozygous C-allele carriers (IRR = 0.71 (CI:0.50-1.00. There was interaction between these MDR1 polymorphisms and intake of red and processed meat in relation to CRC risk. Homozygous MDR1 C3435T C-allele carriers were at 8% increased risk pr 25 gram meat per day (CI: 1.00-1.16 whereas variant allele carriers were not at increased risk (p for interaction = 0.02. COX-2 and BCRP polymorphisms were not associated with CRC risk. There was interaction between NSAID use and MDR1 C3435T and COX-2 T

  8. Interactions between diet, lifestyle and IL10, IL1B, and PTGS2/COX-2 gene polymorphisms in relation to risk of colorectal cancer in a prospective Danish case-cohort study.

    Directory of Open Access Journals (Sweden)

    Vibeke Andersen

    Full Text Available BACKGROUND & AIMS: Diet contributes to colorectal cancer development and may be potentially modified. We wanted to identify the biological mechanisms underlying colorectal carcinogenesis by assessment of diet-gene interactions. METHODS: The polymorphisms IL10 C-592A (rs1800872, C-rs3024505-T, IL1b C-3737T (rs4848306, G-1464C (rs1143623, T-31C (rs1143627 and PTGS2 (encoding COX-2 A-1195G (rs689466, G-765C (rs20417, and T8473C (rs5275 were assessed in relation to risk of colorectal cancer (CRC and interaction with diet (red meat, fish, fibre, cereals, fruit and vegetables and lifestyle (non-steroid-anti-inflammatory drug use and smoking status was assessed in a nested case-cohort study of nine hundred and seventy CRC cases and 1789 randomly selected participants from a prospective study of 57,053 persons. RESULTS: IL1b C-3737T, G-1464C and PTGS2 T8473C variant genotypes were associated with risk of CRC compared to the homozygous wildtype genotype (IRR=0.81, 95%CI: 0.68-0.97, p=0.02, and IRR=1.22, 95%CI: 1.04-1.44, p=0.02, IRR=0.75, 95%CI: 0.57-0.99, p=0.04, respectively. Interactions were found between diet and IL10 rs3024505 (P-value for interaction (P(int; meat=0.04, fish=0.007, fibre=0.0008, vegetables=0.0005, C-592A (P(int; fibre=0.025, IL1b C-3737T (Pint; vegetables=0.030, NSAID use=0.040 and PTGS2 genotypes G-765C (P(int; meat=0.006, fibre=0.0003, fruit 0.004, and T8473C (P(int; meat 0.049, fruit=0.03 and A-1195G (P(int; meat 0.038, fibre 0.040, fruit=0.059, vegetables=0.025, and current smoking=0.046. CONCLUSIONS: Genetically determined low COX-2 and high IL-1β activity were associated with increased risk of CRC in this northern Caucasian cohort. Furthermore, interactions were found between IL10, IL1b, and PTGS2 and diet and lifestyle factors in relation to CRC. The present study demonstrates that gene-environment interactions may identify genes and environmental factors involved in colorectal carcinogenesis.

  9. Climate change: a case study over India

    Energy Technology Data Exchange (ETDEWEB)

    Sahai, A.K. [Indian Institute of Tropical Meteorology, Pune (India)

    1998-12-31

    A brief account of various causes of climate change in recent decades and climate change trends in the Indian region is presented. Local temperature is one of the major climatic elements to record the changes in the atmospheric environment caused by industrialization and urbanization. Literature data show that there is either a cooling tendency or cessation of warming after the late 1950s at most of the Indian industrial cities. A case study of Nagpur, a centrally located city in India, is done to understand the possible causes of cooling. Nagpur is the only city in India for which a long-term record of temperature, for urban (Mayo Hospital) and relatively suburban (Sonegaon Airport) area, is available. The study of the diurnal asymmetry in maximum and minimum temperatures indicates that the role of suspended particulate matter dominates over that of increasing greenhouse gases.

  10. Liverpool Telecare Pilot: case studies

    Directory of Open Access Journals (Sweden)

    Nigel Barnes

    2006-09-01

    Full Text Available Telecare services use information and communications technology (ICT to support the provision of care to people in their own homes. This paper describes a pilot telecare service employed by Liverpool (UK City Council to support a sample of their frail and elderly social services users. The pilot has been running for over two years and has been deployed for 21 individuals in Liverpool. In this paper we present the pilot system and provide real example cases which help to illustrate the benefits of such a system.

  11. Methodology Series Module 2: Case-control Studies.

    Science.gov (United States)

    Setia, Maninder Singh

    2016-01-01

    Case-Control study design is a type of observational study. In this design, participants are selected for the study based on their outcome status. Thus, some participants have the outcome of interest (referred to as cases), whereas others do not have the outcome of interest (referred to as controls). The investigator then assesses the exposure in both these groups. The investigator should define the cases as specifically as possible. Sometimes, definition of a disease may be based on multiple criteria; thus, all these points should be explicitly stated in case definition. An important aspect of selecting a control is that they should be from the same 'study base' as that of the cases. We can select controls from a variety of groups. Some of them are: General population; relatives or friends; and hospital patients. Matching is often used in case-control control studies to ensure that the cases and controls are similar in certain characteristics, and it is a useful technique to increase the efficiency of the study. Case-Control studies can usually be conducted relatively faster and are inexpensive - particularly when compared with cohort studies (prospective). It is useful to study rare outcomes and outcomes with long latent periods. This design is not very useful to study rare exposures. Furthermore, they may also be prone to certain biases - selection bias and recall bias.

  12. Deep Venous Thrombosis with Pulmonary Embolism Related to IVIg Treatment: A Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Michael T. Flannery

    2015-01-01

    Full Text Available IVIg therapy has potentially been related to arterial and venous therapy. We performed an Ovid review focusing on IVIg and thrombotic events. While a few case reports were reviewed case series and case control studies were particularly reviewed in relation to thrombotic events. Outcomes demonstrate a correlation between underlying cardiovascular risk factors with predominately arterial events which typically occurred within 4–24 hours of infusion. While venous events occurred less commonly they were associated with traditional risk factors and occurred later, typically, 1–7 days following infusion of IVIg. Potential causation of thrombotic events was discussed.

  13. Case studies in conservation science

    Science.gov (United States)

    Bisulca, Christina

    The research presented in this dissertation covers three separate topics of conservation as defined by the National Science Foundation: 1) Materials Stabilization, Strengthening, Monitoring, and Repair; 2. Understanding Material Degradation and Aging; and 3) Materials and Structural Characterization of Cultural Heritage Objects (the 'technical study'). The first topic is addressed through a study to assess the consolidant tetraethoxysilane for the stabilization of alum treated wood. Falling under materials degradation studies is a study published in American Museum Novitates to understand how environmental conditions affect the aging of fossil resins from five different deposits. Two separate studies are included in technical study of cultural heritage objects which comprises the third research area of materials characterization. The first is a survey of red dyes used in Chinese paintings from the Ming Dynasty to the Early Republic (1364-1911). The second is a study of the pigments, dyes and binders used in Hawaiian barkcloth (kapa) from the 19th century.

  14. Evaluation of the impact of genetic polymorphisms in glutathione-related genes on the association between methylmercury or n-3 polyunsaturated long chain fatty acids and risk of myocardial infarction: a case-control study

    Directory of Open Access Journals (Sweden)

    Norberg Margareta

    2011-04-01

    Full Text Available Abstract Background The n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid, which are present in fish, are protective against myocardial infarction. However, fish also contains methylmercury, which influences the risk of myocardial infarction, possibly by generating oxidative stress. Methylmercury is metabolized by conjugation to glutathione, which facilitates elimination. Glutathione is also an antioxidant. Individuals with certain polymorphisms in glutathione-related genes may tolerate higher exposures to methylmercury, due to faster metabolism and elimination and/or better glutathione-associated antioxidative capacity. They would thus benefit more from the protective agents in fish, such as eicosapentaenoic+docosahexaenoic acid and selenium. The objective for this study was to elucidate whether genetic polymorphisms in glutathione-related genes modify the association between eicosapentaenoic+docosahexaenoic acid or methylmercury and risk of first ever myocardial infarction. Methods Polymorphisms in glutathione-synthesizing (glutamyl-cysteine ligase catalytic subunit, GCLC and glutamyl-cysteine ligase modifier subunit, GCLM or glutathione-conjugating (glutathione S-transferase P, GSTP1 genes were genotyped in 1027 individuals from northern Sweden (458 cases of first-ever myocardial infarction and 569 matched controls. The impact of these polymorphisms on the association between erythrocyte-mercury (proxy for methylmercury and risk of myocardial infarction, as well as between plasma eicosapentaenoic+docosahexaenoic acid and risk of myocardial infarction, was evaluated by conditional logistic regression. The effect of erythrocyte-selenium on risk of myocardial infarction was also taken into consideration. Results There were no strong genetic modifying effects on the association between plasma eicosapentaenoic+docosahexaenoic acid or erythrocyte-mercury and risk of myocardial infarction risk. When eicosapentaenoic

  15. Work-related posttraumatic upper limb disorder. A case report.

    Science.gov (United States)

    Capodaglio, P; Nigrelli, M P; Malaguti, S; Panigazzi, M; Pierobon, A

    1999-01-01

    In this paper we describe a patient with mor-sensory loss in the right forearm and hand, which persisted more than 2 years after work-related crush trauma of the left hand. Radiographic and electromyographic investigations, somatosensory evoked potentials, CT scans of the encephalus as well as the Minnesota Multiphasic Personality Inventory and the Roarschach test have been performed. On the basis of these investigations, we think this represents a case of conversion disorder with somatic features. Included is a brief overview of other psychological illness with physical findings involving the upper limb.

  16. Transfusion-related acute lung injury: report of two cases.

    Science.gov (United States)

    Čermáková, Z; Kořískta, M; Blahutová, Š; Dvořáčková, J; Brát, R; Valkovský, I; Hrdličková, R

    2012-01-01

    Transfusion-related acute lung injury (TRALI) is a severe life-threatening complication of blood transfusion, characterized by acute lung injury developing within 2-6 h of transfusion. However, TRALI is difficult to diagnose, and the initial report or suspicion of TRALI depends on close collaboration between clinical departments and transfusion centres. A total of 17 adverse post-transfusion reactions were reported to the Blood Centre of the University Hospital Ostrava as suspected TRALI between 2005 and 2010. We report two cases of serious TRALI with different pathogenetic mechanisms.

  17. Sacroiliac joint dysfunction: a case study.

    Science.gov (United States)

    Murray, William

    2011-01-01

    Pain is a widespread issue in the United States. Nine of 10 Americans regularly suffer from pain, and nearly every person will experience low back pain at one point in their lives. Undertreated or unrelieved pain costs more than $60 billion a year from decreased productivity, lost income, and medical expenses. The ability to diagnose and provide appropriate medical treatment is imperative. This case study examines a 23-year-old Active Duty woman who is preparing to be involuntarily released from military duty for an easily correctable medical condition. She has complained of chronic low back pain that radiates into her hip and down her leg since experiencing a work-related injury. She has been seen by numerous providers for the previous 11 months before being referred to the chronic pain clinic. Upon the first appointment to the chronic pain clinic, she has been diagnosed with sacroiliac joint dysfunction. This case study will demonstrate the importance of a quality lower back pain assessment.

  18. Multi-disciplinary data organization and visualization models for clinical and pre-clinical studies: A case study in the application of proton beam radiosurgery for treating spinal cord injury related pain

    Science.gov (United States)

    Verma, Sneha K.; Liu, Brent J.

    2016-03-01

    An increasing adoption of electronic medical records has made information more accessible to clinicians and researchers through dedicated systems such as HIS, RIS and PACS. The speed and the amount at which information are generated in a multi-institutional clinical study make the problem complicated compared to day-to-day hospital workflow. Often, increased access to the information does not translate into the efficient use of that information. Therefore, it becomes crucial to establish models which can be used to organize and visualize multi-disciplinary data. Good visualization in turn makes it easy for clinical decision-makers to reach a conclusion within a small span of time. In a clinical study involving multi-disciplinary data and multiple user groups who need access to the same data and presentation states based on the stage of the clinical trial or the task are crucial within the workflow. Therefore, in order to demonstrate the conceptual system design and system workflow, we will be presenting a clinical trial based on application of proton beam for radiosurgery which will utilize our proposed system. For demonstrating user role and visualization design purposes, we will be focusing on three different user groups which are researchers involved in patient enrollment and recruitment, clinicians involved in treatment and imaging review and lastly the principle investigators involved in monitoring progress of clinical study. Also datasets for each phase of the clinical study including preclinical and clinical data as it related to subject enrollment, subject recruitment (classifier), treatment (DICOM), imaging, and pathological analysis (protein staining) of outcomes.

  19. Case Studies in L2 Teacher Education.

    Science.gov (United States)

    Reichelt, Melinda

    2000-01-01

    Reports on the use of student-generated case studies in an English-as-a-Second-Language teacher education course, including the context, participants classroom procedures and case studies written, as well as students' responses to their use. (Author/VWL)

  20. A Case Study of "Empathetic Teaching Artistry"

    Science.gov (United States)

    Risner, Doug

    2014-01-01

    This case study is one of twenty cases derived from Anderson and Risner's international study of teaching artists in dance, and theatre, which investigated participants' (n=172) artistic and academic preparation in dance, and theatre, initial entry into the teaching artist field, rewards, challenges, and obstacles in participants' work, artists'…

  1. The Danish National Case Study Report

    DEFF Research Database (Denmark)

    Brodersen, Søsser; Jørgensen, Michael Søgaard

    Three case studies from Danish science shops within the environmental field are analysed with respect to societal background, interaction between the involved actors and the societal impact of the co-operation. The report is one of the seven national case study reports from the EU...

  2. Five Misunderstandings About Case-Study Research

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    2006-01-01

    useful for generating hypotheses, whereas other methods are more suitable for hypotheses testing and theory building; (d) the case study contains a bias toward verification; and (e) it is often difficult to summarize specific case studies. This article explains and corrects these misunderstandings one...

  3. Case studies--ergonomics in projects.

    Science.gov (United States)

    Pikaar, Ruud N

    2012-01-01

    The aim of a series of sessions on Company Case Studies, is to learn from practical experiences, to give feed back to researchers on applicability of theories, methods and techniques, and last but not least, to market ergonomics. In order to learn from case material, reports need to be easy accessible and well structured. System ergonomics provides such a structure. Usually a project is not done twice, i.e. with and without ergonomics. Therefore, it is not possible to make comparisons and determine the impact of ergonomics directly. A different approach is needed. It has been suggested at the IEA2006 World Congress, to compile a database of published case studies, each case to be reported in a fixed report format and critically reviewed to enable generalizing the outcomes. This paper proposes such a format. At the IEA2012 World Congress 40 case studies have been accepted, representing applied ergonomics cases in manufacturing, process industries, aviation and logistic systems.

  4. Leishmaniasis in dogs: Case study

    Directory of Open Access Journals (Sweden)

    Aleksić Jelena

    2009-01-01

    Full Text Available The paper presents a case of leishmaniasis in a 2.5-month-old dog imported from France. The clinical examination established a generally poor state of health, expressed cachexia, atrophy of the temporal musculature, weakness of movement, as well as abnormally long and brittle nails. There was also hyperkeratosis of the nose tip and paws. A histological examination of biopsy sections of the altered skin parts showed inflammatory changes in the area of the dermis, together with infiltration of macrophages and a smaller number of lymphocytes, plasmocytes and neutrophil granulocytes in the area around the sebaceous glands and hair follicles. The determined changes correspond to superficial dermatitis. Edema followed by partial degeneration of connective-tissue fibers is observed in connective tissue. A smaller number of intracellular parasitic forms was established in mononuclear cells. A smaller number of oval amastigotes with round dark red nucleis were observed in sections stained using the Gimza method in the cytoplasm of macrophages located in the dermis, but also extracellularly. It was concluded that the dog was diseased with leishmaniasis on the grounds of the clinical picture and the microscopic findings.

  5. From single-case studies to practice-based knowledge: aggregating and synthesizing case studies.

    Science.gov (United States)

    Iwakabe, Shigeru; Gazzola, Nicola

    2009-07-01

    Recent developments in case study methodology reflect a rising interest that clinicians and researchers share in building a clinically useful and empirically sound knowledge base from single-case studies. The present article describes three types of single-case studies (clinical, experimental, systematic) and examines their potential contributions to psychotherapy research. It then lays out three ways in which single-case studies can be aggregated and synthesized to enhance clinical understanding: (a) a case database that allows clinicians to efficiently search for relevant cases, (b) a metasynthesis of single-case studies that integrates common themes across similar cases, and (c) an individual case comparison method in which closely matched cases are compared to identify both therapeutic and hindering processes.

  6. Comparison of methodological and reporting quality: A systematic review of case-control studies related Chinese nursing field%中文护理专业病例对照研究质量的评价

    Institute of Scientific and Technical Information of China (English)

    陈玉芳; 王媛媛; 王娟娟; 王泓午; 窦昊颖

    2014-01-01

    Objective To compare the methodological and reporting quality of case-control studies published in higher impacted nursing periodicals,other nursing journals and compositive medical journals.Methods All nursing specialization and integrative journals in China mainland were searched from the inception till December 2013.The methodological and reporting quality was assessed according to NewcastleOttawa Quality Assessment Scale (NOS) and strengthening the reporting of Observational Studies in Epidemiology Statement (STROBE) respectively.Results The systematic literature search yielded 3 579 publications potentially relevant studies.Then,a total of 94 hteratures met the inclusion criteria were identified.The average score of methodological quality and reporting quality were(4.86±1.33) and (16.11±2.41) respectively.Additionally,there was no significant difference in methodological quality and reporting quality among higher impacted nursing periodical,other nursing journals and compositive medical joumal.Condusions The number of case-control studies in Chinese nursing field revealed an increasing tendency,and these literatures addressed a wide range of research fields.However,most quality of the case-control studies published in China were rela-tively poor,and both methodological and reporting quality should be further improved.%目的 对发表在护理核心期刊、护理非核心期刊和综合性医学期刊上的中文护理专业病例对照研究文献的方法学质量和报告质量进行系统评价.方法 计算机检索中文护理专业病例对照研究的文献,并采用Newcastle-Ottawa Scale (NOS)和Strengthening the Reporting of Observational Studies in Epidemiology(STROBE)量表对文献进行方法学和报告质量评价.结果 检索得到3 579篇文献,根据纳入与排除标准共纳入94篇文献;纳入文献的NOS量表评分为(4.86±1.33)分,STROBE量表评分为(16.11±2.41)分;发表在护理核心期刊上、护理非核心期刊上和

  7. Case studies in Bayesian microbial risk assessments

    Directory of Open Access Journals (Sweden)

    Turner Joanne

    2009-12-01

    Full Text Available Abstract Background The quantification of uncertainty and variability is a key component of quantitative risk analysis. Recent advances in Bayesian statistics make it ideal for integrating multiple sources of information, of different types and quality, and providing a realistic estimate of the combined uncertainty in the final risk estimates. Methods We present two case studies related to foodborne microbial risks. In the first, we combine models to describe the sequence of events resulting in illness from consumption of milk contaminated with VTEC O157. We used Monte Carlo simulation to propagate uncertainty in some of the inputs to computer models describing the farm and pasteurisation process. Resulting simulated contamination levels were then assigned to consumption events from a dietary survey. Finally we accounted for uncertainty in the dose-response relationship and uncertainty due to limited incidence data to derive uncertainty about yearly incidences of illness in young children. Options for altering the risk were considered by running the model with different hypothetical policy-driven exposure scenarios. In the second case study we illustrate an efficient Bayesian sensitivity analysis for identifying the most important parameters of a complex computer code that simulated VTEC O157 prevalence within a managed dairy herd. This was carried out in 2 stages, first to screen out the unimportant inputs, then to perform a more detailed analysis on the remaining inputs. The method works by building a Bayesian statistical approximation to the computer code using a number of known code input/output pairs (training runs. Results We estimated that the expected total number of children aged 1.5-4.5 who become ill due to VTEC O157 in milk is 8.6 per year, with 95% uncertainty interval (0,11.5. The most extreme policy we considered was banning on-farm pasteurisation of milk, which reduced the estimate to 6.4 with 95% interval (0,11. In the second

  8. Summary of case studies for cooperation mechanisms

    DEFF Research Database (Denmark)

    Longa, Francesco Dalla; Klinge Jacobsen, Henrik; Hansen, Lise-Lotte Pade;

    2012-01-01

    This document is a summary report highlighting the main aspect analyzed in the RES4LESS case studies. The document starts with an introductory chapter where the background that led to the selection of the case studies is outlined. In the following three chapters the case studies are presented......, highlighting the most relevant results. A brief chapter concludes the document, giving an outlook on the follow-up activities of the RES4LESS project. This summary is intended not only as an introduction to the RES4LESS cases studies, but also as a guideline to read and interpret the in-depth analysis carried...... out in the final documents that describe the case studies in detail. These documents will be published in September 2012 on the RES4LESS website, www.res4less.eu....

  9. Five case studies of multifamily weatherization programs

    Energy Technology Data Exchange (ETDEWEB)

    Kinney, L; Wilson, T.; Lewis, G. [Synertech Systems Corp. (United States); MacDonald, M. [Oak Ridge National Lab., TN (United States)

    1997-12-31

    The multifamily case studies that are the subject of this report were conducted to provide a better understanding of the approach taken by program operators in weatherizing large buildings. Because of significant variations in building construction and energy systems across the country, five states were selected based on their high level of multifamily weatherization. This report summarizes findings from case studies conducted by multifamily weatherization operations in five cities. The case studies were conducted between January and November 1994. Each of the case studies involved extensive interviews with the staff of weatherization subgrantees conducting multifamily weatherization, the inspection of 4 to 12 buildings weatherized between 1991 and 1993, and the analysis of savings and costs. The case studies focused on innovative techniques which appear to work well.

  10. A Fatal Case of Acute Myeloid Leukaemia-Methotrexate Related or Primary Autoimmune Disease Related: A Rare Case Report.

    Science.gov (United States)

    Agarwal, Saurabh; Kaeley, Nidhi; Gupta, Priyanka; Gupta, Vibha; Bhatia, Rohan

    2016-03-01

    Methotrexate is being used for many years in the treatment of chronic medical disorders e.g. rheumatoid arthritis since 1951. It has been associated with various systemic toxicities and complications including bone marrow suppression and lymphomas. The development of leukaemia in a patient of chronic rheumatoid arthritis is either related with the primary disease or due to the drugs which are used in the treatment like cyclophosphamide. In our present case, a 70-year-old female who was a known case of Rheumatoid Arthritis (RA) and was on methotrexate once a week orally for the past 20 years presented with complaints of loss of appetite, loss of weight and anaemia since 2 months. After thorough examination and investigation, she was diagnosed with acute myeloid leukaemia (AML-M4) with bilateral chest consolidation.

  11. Making a case for case studies in psychotherapy training

    DEFF Research Database (Denmark)

    Mackrill, Thomas Edward; Iwakabe, Shigeru

    2013-01-01

    The evidence debate in psychotherapy pays little attention to developing an evidence base for training practices. Understanding effective training requires an examination of what makes training work. This article examines the role of case studies in psychotherapy training. This has not been...... articulated explicitly or researched systematically in spite of its cardinal importance. An analysis of the role of case studies in psychotherapy training is presented. Reading, watching, or hearing about cases can offer novice psychotherapists access to a closed world; access to psychological theory...... in action; access to whole courses of therapy; access to different approaches; access to significant moments; access to the therapeutic relationship; access to a wide range of client types; access to working in different contexts; and the opportunity of identifying with therapists and clients. Writing...

  12. Case-control Study on Related Factors of Respiratory Tract Infections%小儿反复呼吸道感染发病的相关因素病例对照研究

    Institute of Scientific and Technical Information of China (English)

    陈萧群; 雷玲霞

    2013-01-01

    Objective: To explore the risk factors of recurrent respiratory tract infection (RRTI) in children, develop preventive measures to reduce the prevalence of RRTI in children. Method: Using a population-based case-control study, through the investigation of 148 cases of children with RRTI and 296 healthy controls were parents of children, birth information, living environment information, feeding information , And the unconditional Logistic regression analysis, eliminating confounding factors, find out the cause of risk factors related to pathogenesis of RRTI. Result: Per capita living area less than 13 square meters (0R= 3. 620;95CI:0. 348-12. 256); Passive smoking (0R = 3. 159 ;95CI:0. 368-9. 450); not breastfeed (OR= 3. 237;95CI:0. 394-11. 432) is RRTI disease related risk factors. Conclusion: Breast-feeding should be promoted, reducing passive smoking, keeping the living environment of air circulation in order to reduce the incidence of RRTI.%目的:探讨小儿反复呼吸道感染 ( RRTI) 的危险因素,为降低儿童 RRTI 发病率提供理论依据.方法:设计方案为病例对照研究,调查148例RRTI患儿和296例健康对照组儿童的父母情况,出生时情况,生活环境,喂养情况,并采用非条件 Logistic 回归分析,排除混杂因素,找出导致RRTI发病的相关危险因素.结果:研究显示人均居住面积<13m2(OR= 3.620;95CI:0.348-12.256);同住人吸烟(OR=3.159;95CI:0.368-9.450);未进行母乳喂养(OR= 3.237;95CI:0.394-11.432)是RRTI发病的相关危险因素.结论:为了减少RRTI的发病率,应提倡母乳喂养,减少被动吸烟,保持居住环境空气流通.

  13. Market Basket Analysis: a new tool in ecology to describe chemical relations in the environment--a case study of the fern Athyrium distentifolium in the Tatra National Park in Poland.

    Science.gov (United States)

    Samecka-Cymerman, Aleksandra; Stankiewicz, Andrzej; Kolon, Krzysztof; Kempers, Alexander J; Leuven, Rob S E W

    2010-09-01

    In this study, the novel data mining technique Market Basket Analysis (MBA) was applied for the first time in biogeochemical and ecological investigations. The method was tested on the fern Athyrium distentifolium, in which we measured concentrations of the elements Ca, Cd, Cr, Cu, Fe, K, Mg, Mn, Na, Ni, Pb, and Zn. Plants were sampled from sites with different types of bedrock in the Tatra National Park in Poland. MBA was used to investigate whether specimens of Athyrium distentifolium that contain elevated levels of certain elements occur more frequently on a specific type of bedrock and to identify relationships between the type of bedrock and the concentrations of the elements in this fern. The results were compared with those of the commonly used principal component and classification analysis (PCCA) technique. MBA and PCCA ordination both yielded distinct groups of ferns growing on different types of bedrock. Although the results of MBA and PCCA were similar, MBA has the advantage of being independent of the size of the data set. In addition, MBA revealed not only dominant elements but, in the case of limestone bedrock, also showed very low concentrations of Cd, Fe, Mn, and Pb in ferns growing on this type of parent material. MBA, thus, appeared to be a promising data mining method to reveal chemical relations in the environment as well as the accumulation of chemical elements in bioindicators. This technique can be used to reveal associations and correlations among items in large data sets collected on a national or even larger scale.

  14. [Ergotamine poisoning: a case study].

    Science.gov (United States)

    Zapalska-Pozarowska, Karolina; Szponar, Jarosław; Górska, Agnieszka; Niewiedzioł, Marek

    2012-01-01

    Ergotamine is a well known pharmacological remedy applied in neurology (treatment of vascular headache) and in obstetrics (abortive remedy, uterus atony). But today it is rarely used, because of new safer anti-migraine medicine (triptanes) which cause fewer side effects. According to obstetrical indications ergotamine is applied only in hospital treatment. For that reason, cases of intoxication by this class of drugs are rarely observed. Ergotamine causes constriction of the blood vessels through the blockade of alpha-receptors and stimulation of the serotonin-receptors on the walls of blood vessels both in the central nervous system and in peripheral circulation. Intoxication/overdose symptoms may appear on application of therapeutic dose by sensitive patients, mostly by patients with migraine headache using ergotamine preparation for relief of migraine attacks. In the Regional Centre of Clinical Toxicology, a 21-year-old patient was hospitalized. She took about 20 tablets of Cafergot (complex preparation containing 1mg ergotamine tartare and 100mg caffeine). During her stay on the ward, typical symptoms of severe poisoning were observed: nausea, severe vomiting, dizziness, decreased blood pressure without perceptible pulse, narrowing of the blood vessels in the extremities of the body (peripheral vasoconstriction) - paresthesia, digital cyanosis, refrigeration of legs, angina. Due to taking once of a great dose of the drug by the patient, violent process of intoxication, possibility of dangerous complication and also the unavailability of specific antidotes and lack of efficient methods of extracorporeal elimination of the drug, the patient was intensively controlled and symptomatic treatments according to the law of intensive therapy was applied.

  15. Book Review: EU External Relations Law: Text, Cases and Materials

    Directory of Open Access Journals (Sweden)

    Graham Butler

    2014-06-01

    Full Text Available This latest textbook contributing to the field of EU external relations law is unique in that it is the first such book in the post-Treaty of Lisbon environment to take a wide-angled look on as many aspects of the growing area as it continues to develop within the legal parameters as set by the Treaties, and it is suitably placed to become the core text for teaching this expanding EU policy field. In their book, EU External Relations Law: Text, Cases and Materials, Van Vooren and Wessel seek to fill the gap in up-to-date literature from a legal standpoint in the field of external relations of the EU, with a book that is suitable for delivery as a core textbook for students of all levels. Their analysis covering fifteen long chapters offers the reader a comprehensive insight into the world of EU external relations law, and allows for a thoroughly better understanding of all the encapsulated issues that are at play.

  16. Outage management: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Barriere, M.T. (Brookhaven National Lab., Upton, NY (United States)); Roberts, K.H. (California Univ., Berkeley, CA (United States). Walter A. Haas School of Business)

    1992-01-01

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission's (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study.

  17. Outage management: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Haber, S.B.; Barriere, M.T. [Brookhaven National Lab., Upton, NY (United States); Roberts, K.H. [California Univ., Berkeley, CA (United States). Walter A. Haas School of Business

    1992-09-01

    Outage management issues identified from a field study conducted at a two-unit commercial pressurized water reactor (PWR), when one unit was in a refueling outage and the other unit was at full power operation, are the focus of this paper. The study was conduced as part of the US Nuclear Regulatory Commission`s (NRC) organizational factors research program, and therefore the issues to be addressed are from an organizational perspective. Topics discussed refer to areas identified by the NRC as critical for safety during shutdown operations, including outage planning and control, personnel stress, and improvements in training and procedures. Specifically, issues in communication, management attention, involvement and oversight, administrative processes, organizational culture, and human resources relevant to each of the areas are highlighted by example from field data collection. Insights regarding future guidance in these areas are presented based upon additional data collection subsequent to the original study.

  18. The first case of atrial fibrillation-related graft kidney infarction following acute pyelonephritis.

    Science.gov (United States)

    Tsai, Shang-Feng

    2014-01-01

    Native renal infarction is uncommon in patients with atrial fibrillation (AF)-related thromboembolism. Graft infarction is also rare, with such cases mostly occurring in the main graft artery postoperatively. To date, there have been no studies of AF-related graft kidney infarction. We herein describe the first case of AF-related graft kidney infarction. The clinical manifestations of this condition mimic and follow those of acute pyelonephritis; therefore, these diseases should be differentially diagnosed as early as possible using lactic dehydrogenase testing and computed tomography. Aggressive treatment with intravascular thrombolysis should be administered, even when the diagnosis is delayed, in order to restore a viable renal function.

  19. Case Study Methodology and Homelessness Research

    Directory of Open Access Journals (Sweden)

    Jill Pable

    2013-10-01

    Full Text Available This paper describes the potential suitability of case study methodology for inquiry with the homeless population. It references a research study that uses case study research method to build theory. This study's topic is the lived experience of destitute individuals who reside in homeless shelters, and explores the homeless shelter built environment's potential influence on resident satisfaction and recovery. Case study methodology may be appropriate because it explores real-life contextual issues that characterize homelessness and can also accommodate the wide range of homeless person demographics that make this group difficult to study in a generalized fashion. Further, case study method accommodates the need within research in this area to understand individualized treatments as a potential solution for homelessness.

  20. Case Study on Quality Education

    Science.gov (United States)

    Habib, Zahida

    2011-01-01

    Quality of Education, especially at Primary level, is an important issue to be discussed at the International Forum. This study highlights the quality of primary education through a comparison of the quality of Community Model Schools and Govt. Girls Primary Schools in Pakistan. Community Model Schools were established under Girls Primary…

  1. Odontoma: a retrospective study of 73 cases

    Energy Technology Data Exchange (ETDEWEB)

    An, Seo Young; An, Chang Hyeon; Choi, Karp Shik [School of Dentistry, Kyungpook National University, Daegu (Korea, Republic of)

    2012-06-15

    The purpose of the present study was to retrospectively evaluate the clinical findings and treatment results for impacted permanent teeth associated with odontomas. We retrospectively investigated 73 odontomas in 72 patients who visited Kyungpook National University Dental Hospital from April 2004 through November 2011. The study was performed using medical records, panoramic radiographs, and pathological reports. Data gathered included age, gender, location, chief complaints, effects on dentition, and treatment of odontoma and the impacted tooth associated with odontoma. Most compound odontomas (46.7%) were found in the second decade and complex odontomas were not related to age. Odontomas showed no gender predilection. Fifty-five cases (75.3%) of odontomas were detected on routine dental radiographs. Sixty percent of compound odontomas occurred in the canine area and 57.1% of complex odontomas in the molar areas. Impaction of permanent teeth (61.6%) was the most common complication on the adjacent teeth. Most odontomas (84.9%) were removed surgically and impacted permanent teeth were managed by surgical removal (53.2%), orthodontic treatment (25.5%), or surgical repositioning (6.4%). There was a statistically significant relation between age and preservation of the impacted permanent teeth associated with odontomas (p<0.01). Early detection and treatment of odontomas increase the possibility of preservation of the impacted tooth. Therefore, it would be suggested that periodic panoramic examination during the first and second decade of life might be beneficial for the early detection and better prognosis of odontomas.

  2. Associative Visual Agnosia: A Case Study

    Directory of Open Access Journals (Sweden)

    A. Charnallet

    2008-01-01

    Full Text Available We report a case of massive associative visual agnosia. In the light of current theories of identification and semantic knowledge organization, a deficit involving both levels of structural description system and visual semantics must be assumed to explain the case. We suggest, in line with a previous case study [1], an alternative account in the framework of (non abstractive episodic models of memory [4].

  3. Arctic bioremediation -- A case study

    Energy Technology Data Exchange (ETDEWEB)

    Smallbeck, D.R.; Ramert, P.C. (Harding Lawson Associates, Novato, CA (United States)); Liddell, B.V.

    1994-05-01

    This paper discusses the use of bioremediation as an effective method to clean up diesel-range hydrocarbon spills in northern latitudes. The results of a laboratory study of microbial degradation of hydrocarbons under simulated arctic conditions showed that bioremediation can be effective in cold climates and led to the implementation of a large-scale field program. The results of 3 years of field testing have led to a significant reduction in diesel-range hydrocarbon concentrations in the contaminated area.

  4. A Case-control Study of Mother-related Factors for Late Preterm Births%晚期早产母源性因素的病例对照研究

    Institute of Scientific and Technical Information of China (English)

    柳锡永; 刘小媚; 金志彪; 徐兰飞; 吴燕

    2015-01-01

    目的:探讨晚期早产发生的母源性影响因素。方法选取2012年1月至2013年12月住院分娩的970例晚期早产产妇为研究对象,并以同期早期早产(207例)和全部足月产(11985例)产妇为对照,比较分析晚期早产的母源性影响因素。结果年龄<20岁、外来流动人口、小学及以下文化程度、无业人员、双胎妊娠、无定期产前检查、胎膜早破、前置胎盘、胎盘早剥、妊娠合并肝内胆汁淤积与晚期早产和早期早产均有关(P<0.01);流产次数≥3次、胚胎移植术妊娠、妊娠合并高血压与晚期早产有关(P<0.05、0.01);妊娠合并贫血与早期早产有关(P<0.01)。结论除早产共有的影响因素外,流产次数≥3次、胚胎移植术妊娠、妊娠合并高血压是晚期早产独有的母源性因素,应采取针对性的措施减少和预防晚期早产的发生。%Objective To investigate the mother-related factors of late preterm births.Methods A case-control study of mother-related factors for late preterm births from January 2012 to December 2013 was performed, 970 women with late preterm birth as the case group, 207 women with early preterm birth and 11985 women with term birth as the control group.Results Age below 20 years old, the lfoating population, primary school education, the unemployed, twin pregnancies, without regular prenatal examination, premature rupture of fetal membranes, placenta praevia, placental abruption and pregnancy with intrahepatic cholestasis were associated with late preterm birth and early preterm birth(P<0.01). More than 3 abortion, regnancy embryo thansplantation and pregnancy with hypertension were associated with late preterm birth(P<0.05 and 0.01). Pregnancy with anemia was associated with early preterm birth(P<0.01).Conclusion In addition to the common inlfuencing factors of preterm birth, more than 3 abortion, regnancy embryo transplantation and pregnancy with

  5. Case Study of above Average Elementary School

    Science.gov (United States)

    Mendez-Morse, Sylvia; Klinker, JoAnn Franklin

    2005-01-01

    This case study explores the duty of midmanagement administrators to enforce district policies with which they do not necessarily agree. The case addresses the issues of moral leadership, distribution of power, emotional responses that impact decision making, class differences, and equity. It also examines the role conflict that many married…

  6. Abbreviated Case Studies in Organizational Communication

    Science.gov (United States)

    Wanguri, Deloris McGee

    2005-01-01

    The cases contained within organizational communication texts are generally two to three pages, often followed by questions. These case studies are certainly useful. They generally describe events in the present, provide some type of organizational context, include first-hand data, include a record of what people say and think, develop a…

  7. Case Study Report about Gender Impact Assessment

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Agustin, Lise Rolandsen

    2013-01-01

    The aim of this national case study report is to take a closer look at the use of Gender Impact Assessments in Denmark in order to describe the Danish implementation of this specific Gender Mainstreaming method. By way of analyzing two selected cases (two law proposals put forward by The Danish...

  8. Music in context : Four case studies

    NARCIS (Netherlands)

    Randwijck, R.J.C. van

    2008-01-01

    In his thesis entitled “Music in Context. Four Case Studies”, R.J.C. van Randwijck investigates the context in which music has been created. It is a search in Four Case Studies, approaching four pieces of music from the context in which they were written in order to understand their meaning. The inv

  9. Case studies of steel structure failures

    Directory of Open Access Journals (Sweden)

    P. Bernasovský

    2010-01-01

    Full Text Available The contribution deals with some case studies of steel structure failures, which happened in Slovakia a few years ago. Features of cracking are illustrated on real cases of breakdowns in the transmission gas pipelines, at the cement works and in the petrochemical indus-try. All failures were caused by an incorrect technical approach. Possible remedial measures are proposed.

  10. Numbers of Relative Equilibria in the Planar Four-Vortex Problem: Some Special Cases

    Science.gov (United States)

    Tsai, Ya-Lun

    2016-11-01

    Three planar four-vortex problems are considered in this paper. In the (3+1) -vortex problem, we study the relative equilibria of the four point vortices when one vortex has zero vorticity and the other three with nonzero vorticities form an equilateral triangle. In the (1+3) -vortex problem, we study the limiting cases of the relative equilibria when one of the four point vortices has fixed nonzero vorticity and other vorticities approach zero. The third problem is the case of vanishing total vorticity. All problems involve two real vorticity parameters. We consider all meaningful pairs of parameters and find there can only be 4, 8, 9 or 10 relative equilibria in the (3+1) -vortex problem, and 8, 10, 12 or 14 relative equilibria in the (1+3) -vortex problem. For the case of zero total vorticity, there are 0, 1 or 2 collinear relative equilibria and 2, 3 or 4 strictly planar relative equilibria. We completely classify parameters according to the different numbers of relative equilibria. For all cases, we reduce them to the problems of counting common zeros in an open region of {{{R}}}2 for polynomial systems with two equations, two variables, and two parameters. We propose a method to count zeros for such type of systems for all parameters in an open region of R2 through symbolic computations. Therefore, all of our results are proved rigorously.

  11. Implementing Product Platforms: A Case Study

    DEFF Research Database (Denmark)

    Nielsen, Ole Fiil; Mortensen, Niels Henrik

    2006-01-01

    The paper describes a case study dealing with the process of creating and implementing a product platform. The paper espessially deals with the fact that to obtain the benefits of platforms a permanent change in behaviour in product development must be ensured. This change in behaviour requires...... acceptance and approval from the organisation in general and the commitment from management to enforce agreed-upon decisions. The case study itself was performed in the Danish company LEGO Group. The case study had two objectives: To create a technical architecture and align this architecture...

  12. Case study in professionally-oriented training

    Directory of Open Access Journals (Sweden)

    Valitov Shamil M.

    2016-01-01

    Full Text Available Modern educational technologies are based on competence approach and focus on the future professional activity. Case study is one of the most significant technologies in modern higher education. The basic concepts used in the case study method are a “situation” and an “analysis”, as well as their derivative - “analysis of the situation”. The case study method of is one of the best tools for gaining experience, as it investigates practical situations that occur in managerial job. It combines theoretical knowledge with the analysis of the actual practical experience in accordance with a major. Doing case studies students read the description of the situation and offer divergent projects of managerial decisions that could be used by real managers dealing with the problem posed by the case study author. Answers to the questions posed in the case description are not given, as a rule, since the main purpose in the case analysis is to organize a discussion in the classroom or provoke speculations of those who do the self-study.

  13. Antiphospholipid syndrome: A case study

    Energy Technology Data Exchange (ETDEWEB)

    Davies, T. [Royal Adelaide Hospital, Adelaide, SA (Australia). Department of Nuclear Medicine

    1998-03-01

    Full text: A forty-two-year-old male presented to the Royal Adelaide Hospital with symptoms of increasing shortness of breath, swelling in both ankles, petechial rash and blood in his sputum. Initial investigations showed cardiomegaly, right ventricular hypertrophy, patchy lung infiltrates, a platelet count of 1500 and a clotting time of 60 seconds. A V/Q scan indicated a high probability of pulmonary embolism. Further investigations showed that the patient was positive for lupus anticoagulant and cardiolipin antibodies. A diagnosis of primary antiphospholipid syndrome was made. The patient``s high risk of strokes and hemorrhaging prompted investigation by a {sup 99}mTc-HMPAO brain scan. Further V/Q scans were performed to follow up the initial finding of multiple pulmonary embolism and a R-L shunt study was performed to investigate a left subclavian murmur. The patient was admitted for four weeks and began treatment which included cyclaphosphamide, corticosteroids and plasmaphoresis and was discharged when stable. Over the next six months he was re admitted three times for relapse of antiphospholipid syndrome. On his fourth admission he collapsed and died five hours after admission. Cause of death was due to cardiac arrhythmia secondary to severe right ventricular hypertrophy and dilation. The effects of antiphospholipid syndrome was believed to be responsible for this outcome.

  14. Energy Audit: A Case Study

    Directory of Open Access Journals (Sweden)

    Sanjay Kumar

    2013-06-01

    Full Text Available This India is the Fifth largest producer of Electricalenergy in the world. Despite such achievements the gapbetween demand and supply of electrical energy is increasingevery year and power sector is highly capital – intensive. Thusthe deficit in installed capacity was nearly 10000MWper year.So the gap between demand and supply is continuouslyincreasing day by day. An energy audit is a study of a plant orfacility to determine how and where energy is used and toidentify methods for energy savings. The opportunities lie inthe use of existing renewable energy technologies, greaterefforts at energy efficiency and the dissemination of thesetechnologies and options. This thesis provides an overview of ageneral energy conservation measures (ECMs that can becommonly recommended for NIT Hamirpur. It should be notedthat the Energy auidut presented in this paper does not pretendto be exhaustive nor comprehensive. It provides merely toindicate some of the options that energy auditor can considerwhen performing an analysis of this institute. Energyconservation and exploration of new energy avenues are thewell accepted solution to fulfil the demand in future. The totalcost of energy plays a vital role in determining the product costof a commodity. Therefore the identification of potential energysavings and implementation for a given institutional facility isunimportant to ensure its competitive advantage over otherinstitute. This paper work presents such energy saving methodsin a methodological approach, experienced during a detailedenergy audit of NIT Hamirpur.

  15. Psychopathology Related to Energy Drinks: A Psychosis Case Report

    Science.gov (United States)

    Martin-Larregola, Maria; Gomez-Arnau, Jorge; Correas-Lauffer, Javier

    2017-01-01

    Energy drinks (ED) are nonalcoholic beverages that have caffeine as their most common active substance. The rapid expansion of ED consumption has created concern in the scientific community as well as in the public opinion. We report a psychotic episode probably triggered by ED abuse in a young adult without previous psychotic disorders. We have reviewed the literature regarding the relationship between caffeine, energy drinks, and psychopathology. Few articles have been published about mental health effects of energy drinks and caffeine abuse. Nevertheless, this relationship has been suggested, specifically with anxiety disorders, manic episodes, suicide attempts, psychotic decompensation, and substance use disorder. ED consumption could represent a global public health problem because of the potential severe adverse effects in mental and physical health. To our knowledge, this article is probably the first case of psychosis related to ED abuse in an individual without previous psychotic disorders. PMID:28116203

  16. Structural logical relations with case analysis and equality reasoning

    DEFF Research Database (Denmark)

    Rasmussen, Ulrik Terp; Filinski, Andrzej

    2013-01-01

    requires the assertion logic to be extended with reasoning principles not present in the original presentation of the formalization method. We address this by generalizing the assertion logic to include dependent sorts, and demonstrate that the original cut elimination proof continues to apply without......Formalizing proofs by logical relations in the Twelf proof assistant is known to be notoriously difficult. However, as demonstrated by Schürmann and Sarnat [In Proc. of 23rd Symp. on Logic in Computer Science, 2008] such proofs can be represented and verified in Twelf if done so using a Gentzen......-style auxiliary assertion logic which is subsequently proved consistent via cut elimination. We demonstrate in this paper an application of the above methodology to proofs of observational equivalence between expressions in a simply typed lambda calculus with a call-by-name operational semantics. Our use case...

  17. Case studies in intelligent computing achievements and trends

    CERN Document Server

    Issac, Biju

    2014-01-01

    Although the field of intelligent systems has grown rapidly in recent years, there has been a need for a book that supplies a timely and accessible understanding of this important technology. Filling this need, Case Studies in Intelligent Computing: Achievements and Trends provides an up-to-date introduction to intelligent systems.This edited book captures the state of the art in intelligent computing research through case studies that examine recent developments, developmental tools, programming, and approaches related to artificial intelligence (AI). The case studies illustrate successful ma

  18. Assessment of global phase uncertainty in case-control studies

    Directory of Open Access Journals (Sweden)

    van Houwelingen Hans C

    2009-09-01

    Full Text Available Abstract Background In haplotype-based candidate gene studies a problem is that the genotype data are unphased, which results in haplotype ambiguity. The measure 1 quantifies haplotype predictability from genotype data. It is computed for each individual haplotype, and for a measure of global relative efficiency a minimum value is suggested. Alternatively, we developed methods directly based on the information content of haplotype frequency estimates to obtain global relative efficiency measures: and based on A- and D-optimality, respectively. All three methods are designed for single populations; they can be applied in cases only, controls only or the whole data. Therefore they are not necessarily optimal for haplotype testing in case-control studies. Results A new global relative efficiency measure was derived to maximize power of a simple test statistic that compares haplotype frequencies in cases and controls. Application to real data showed that our proposed method gave a clear and summarizing measure for the case-control study conducted. Additionally this measure might be used for selection of individuals, who have the highest potential for improving power by resolving phase ambiguity. Conclusion Instead of using relative efficiency measure for cases only, controls only or their combined data, we link uncertainty measure to case-control studies directly. Hence, our global efficiency measure might be useful to assess whether data are informative or have enough power for estimation of a specific haplotype risk.

  19. Case Study Orientation for New Teachers.

    Science.gov (United States)

    Richardson, James M.

    1979-01-01

    This article describes Oldfields School's systematic orientation program for beginning teachers. They meet as a group and discuss case studies, which give substance to the regulations and policies listed in the school handbooks. (SJL)

  20. Towards More Case Study Research in Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Tom Duxbury

    2012-03-01

    Full Text Available Entrepreneurship as an emerging discipline has made good strides, but according to some, has fallen short of bringing its theory and literature up to the standards of others in the management sciences. Rich with the descriptive detail needed for insightful theory building in entrepreneurship, scholars have called for more case study research, particularly those incorporating non-retrospective and longitudinal observations. At the same time however, it has become rare to find such research published in A-level journals dedicated to entrepreneurship. A survey presented here of major entrepreneurship journals over the past six years revealed a publication rate of only 3% using the case study method. This presents a major impediment for developing fresh research in this field based upon the study of real cases. The author explores how the case study method has been applied to entrepreneurship research and provides recommendations for improved publication rates.

  1. Child Survivor of War: A Case Study

    Science.gov (United States)

    Roysircar, Gargi

    2004-01-01

    This article examines the history of a Bosnian survivor of war living in the U.S. using the extended case method. Clinical issues related to acculturative stress, posttraumatic stress disorder, and identity are analyzed. Suggested treatment includes existential therapy and its cognitive--behavioral applications, didactic education on trauma,…

  2. Anencephaly: A pathological study of 41 cases

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    C Panduranga

    2012-01-01

    Full Text Available Background : Anencephaly is a lethal neural tube defect which is due to the defective closure of rostral pore of neural tube. In more than 50% of cases it is associated with other systemic anomalies. Hence this study was undertaken to assess pathological parameters associated with anencephaly in particular attention to associated systemic anomalies. Materials and Methods: It is a study on 41 anencephaly fetuses conducted in the Department of Pathology. The period of study is from January 2001 to December 2011. Results: Out of 41 cases, 30 (73% cases showed presence of systemic anomalies, 48.5% of the cases were observed in primigravida. Most common associated anomaly was spina bifida followed by gastrointestinal anomalies. Conclusion: Pathological examination of the abortus is essential to document the associated anomalies.

  3. Case studies of nurseries in Malawi

    DEFF Research Database (Denmark)

    Namoto, M.; Likoswe, M.G.

    This study of 42 case studies of nurseries was made as part of a major sample survey of 360 nurseries in 6 districts in Malawi. The purpose of the study was to let the small nurseries in the country explain in their own words how they source seed, how and for whom they produce seedlings...

  4. Predicting Students Drop Out: A Case Study

    Science.gov (United States)

    Dekker, Gerben W.; Pechenizkiy, Mykola; Vleeshouwers, Jan M.

    2009-01-01

    The monitoring and support of university freshmen is considered very important at many educational institutions. In this paper we describe the results of the educational data mining case study aimed at predicting the Electrical Engineering (EE) students drop out after the first semester of their studies or even before they enter the study program…

  5. Giftedness, Trauma, and Development: A Qualitative, Longitudinal Case Study

    Science.gov (United States)

    Peterson, Jean Sunde

    2014-01-01

    A qualitative, longitudinal, phenomenological case study explored how a gifted female experienced various life events and aspects of development during adolescence and young adulthood (ages 15-30 years), particularly as related to multiple traumatic experiences, which were revealed late in the first year of the study. Additional experiences, well…

  6. Metabolic Derangements in Lichen Planus - A Case Control Study

    Science.gov (United States)

    Kar, Bikash Ranjan; Panda, Maitreyee

    2016-01-01

    Introduction An association between psoriasis and metabolic syndrome has been established in previous studies. Lichen Planus (LP) is also a chronic inflammatory disease morphologically related to psoriasis and few studies have shown association of metabolic derangements in LP. Aim To study the association of metabolic derangements in LP. Materials and Methods A prospective case control study was undertaken for a period of one year. Age and sex matched patients of LP and other non-inflammatory diseases were taken as cases and controls respectively. Data on height, weight, lipid profile and fasting blood glucose levels were collected for all the patients. Body Mass Index (BMI) was calculated. Results A total of 80 patients were recruited, 40 cases and 40 controls. The mean values for all the lipid and glucose parameters were high in cases as compared to controls with significant p-values. Conclusion In the present study metabolic derangements were seen in patients with LP. PMID:28050485

  7. Hubble Case Studies of Transiting Giant Exoplanets

    Science.gov (United States)

    Wilkins, Ashlee N.; Deming, Drake; Barker, Adrian; Benneke, Björn; Delrez, Laetitia; Gillon, Michaël; Hamilton, Douglas P.; Jehin, Emmanuel; Knutson, Heather; Lewis, Nikole K.; Madhusudhan, Nikku; Mandell, Avi; McCullough, Peter R.; Wakeford, Hannah R.

    2017-01-01

    The study of planets around other stars has entered a science-rich era of characterization, in which detailed information about individual planets can be inferred from observations beyond mere detection, which only yields bulk properties like mass or radius. Characterization probes more revealing quantities such as chemical abundances, albedo, and temperature/pressure profiles, which allow us to address larger questions of planet formation mechanisms, planetary evolution, and, eventually, habitability and presence of biosignature gases. The primary method for characterization of close-in planets is transit spectroscopy. This dissertation talk will focus on transiting exoplanet case studies with the Hubble Space Telescope’ Wide-Field Camera-3 (WFC-3) as a tool of exoplanet characterization in a near-infrared band dominated by strong water features. I will first present a characterization the WFC-3 systematic effects that must be mitigated to extract the incredibly small (tens to 200 parts per million) signals, and then a study of four transiting giant planets (HATS-7b, HAT-p-3b, HD 149026b, and WASP-18b) in transmission, and two (WASP-18b and CoRoT-2b) in eclipse. Finally, I will discuss the role of transit timing monitoring of WASP-18b with HST and other observatories as another clue to its evolution as a close-in, massive planet. The five planets range from Neptune-class to Super-Jupiter-class in size/mass. Though these planets may be relatively rare, their observability represents a unique opportunity to probe planet formation and evolution, as well as atmospheric structures in a high-irradiation environment. These observations also yield insights into aerosols (i.e. clouds/hazes) in the atmosphere; clouds and/or hazes should significantly impact atmospheric chemistry and observational signatures, and we as a community must get a better handle on the phenomenon of aerosols in advance of the next generation of space observatories, including JWST and WFIRST

  8. Terazosin for the treatment of trauma-related nightmares: a report of 4 cases.

    Science.gov (United States)

    Nirmalani-Gandhy, Anjali; Sanchez, Deborah; Catalano, Glenn

    2015-01-01

    The selective α1-adrenergic antagonist prazosin has been shown in multiple studies to be effective in targeting trauma-related nightmares in posttraumatic stress disorder. There are limited data regarding the effectiveness of another selective α1-adrenergic antagonist terazosin for the treatment of trauma-related nightmares. We present 4 cases in which terazosin was effectively used to treat nightmares as a second-line agent after prazosin failure. Further studies are needed to validate terazosin as an alternative to prazosin for the treatment of posttraumatic stress disorder-related nightmares.

  9. Case Study Research Methodology in Nursing Research.

    Science.gov (United States)

    Cope, Diane G

    2015-11-01

    Through data collection methods using a holistic approach that focuses on variables in a natural setting, qualitative research methods seek to understand participants' perceptions and interpretations. Common qualitative research methods include ethnography, phenomenology, grounded theory, and historic research. Another type of methodology that has a similar qualitative approach is case study research, which seeks to understand a phenomenon or case from multiple perspectives within a given real-world context.

  10. Gigantic Suprapubic Lymphedema: A Case Study

    Science.gov (United States)

    Tanhaeivash, Roozbeh; Franiel, Tobias; Grimm, Marc-Oliver

    2016-01-01

    We present the first case study of idiopathic gigantic suprapubic lymphedema and buried penis treated with puboscrotal reconstruction in a patient with initial extreme obesity after an extensive weight reduction (120 kg). Massive localized lymphedema of the suprapubic region should be differentiated from the scrotal type. Severe lymphedema could not resolve on its own and weight reduction does not seem to be helpful in such cases. PMID:27574599

  11. RELATION BETWEEN ORGANIZATIONAL JUSTICE AND PERFORMANCE ADIYAMAN CASE

    Directory of Open Access Journals (Sweden)

    Hüseyin ALKIŞ

    2015-12-01

    Full Text Available This research is based on the idea that justice perception in the workplace is one of the most important factors that affect working performance of employees. In this sense, it has been studied that whether the levels of organizational justice perception of teachers in Adiyaman differ or not according to their demographic features. In addition the relation between organizational justice and working performance has been investigated. The sample group of the study is composed of 345 randomly selected teachers among 3300 teachers who worked in Adıyaman in 2013-2014 academic year. Quantitative research method was used in this study and data were obtained using descriptive-relational data model. attitude scales of organizational justice and performance were used as data collection tool. Factor analysis in analyzing the data, the arithmetic mean, standard deviation, T-test, one-way analysis of variance (ANOVA and Turkey HSD tests were used. The study shows that there is no difference in the perception of organizational justice by means of gender, marital status, union membership status, age, education level, length of service and length of service in the profession in schools vary according to the variable, but some differences have been found according to subject, monthly fee,the number of teachers in school and school type. In addition to these results, it can said that there is a weak relationship between performance and organizational justice in the same direction.

  12. Mitragynine 'Kratom' related fatality: a case report with postmortem concentrations.

    Science.gov (United States)

    McIntyre, Iain M; Trochta, Amber; Stolberg, Susan; Campman, Steven C

    2015-03-01

    A 24-year-old man whose medical history was significant for alcohol abuse and depression was found unresponsive in bed. He had several prior suicide attempts with 'pills' and had also been hospitalized for an accidental overdose on a previous occasion. Autopsy findings were unremarkable apart from pulmonary edema and congestion, and urinary retention. Postmortem peripheral blood initially screened positive for mitragynine 'Kratom' (by routine alkaline drug screen by gas chromatography-mass spectrometry, GC-MS), which was subsequently confirmed by a specific GC-MS selective ion mode analysis following solid-phase extraction. Concentrations were determined in the peripheral blood (0.23 mg/L), central blood (0.19 mg/L), liver (0.43 mg/kg), vitreous (<0.05 mg/L), urine (0.37 mg/L) and was not detected in the gastric. Therapeutic concentrations of venlafaxine, diphenhydramine and mirtazapine were also detected together with a negligible ethanol of 0.02% (w/v). The results are discussed in relation to previous cases of toxicity, and the lack of potential for mitragynine postmortem redistribution.

  13. Alcohol effects on family relations: a case study Repercussiones del alcoholismo en las relaciones familiares: estudio de caso acerca del tema Repercussões do alcoolismo nas relações familiares: estudo de caso

    Directory of Open Access Journals (Sweden)

    Amanda Márcia dos Santos Reinaldo

    2008-08-01

    Full Text Available Problems related to alcohol abuse have been associated to different factors, regardless of the causes attributed to this phenomenon. Alcohol consumption and dependence is considered a public health problem and deserve attention because of the social, work, family, physical, legal and violence-related risks it represents. This study aimed to identify the effects of alcoholism on family relations and, by means of case management, to encourage the recovery of these relationships. The results show that the problems caused by alcohol abuse impose profound suffering to family members, which contributes to high levels of interpersonal conflict, domestic violence, parental inadequacy, child abuse and negligence, financial and legal difficulties, in addition to clinical problems associated to it.Los problemas relacionados al uso de alcohol han sido asociados a diversos factores, independiente de las causas atribuidas al fenómeno en cuestión. Cuando consideramos que el consumo y la dependencia de alcohol incrementan el riesgo para problemas sociales, de trabajo, familiares, físicos, legales y con violencia, podemos afirmar que merece atención y se configura como un problema de salud pública. La finalidad del estudio fue identificar las repercusiones del alcoholismo en las relaciones familiares y, por medio de la gestión de casos, incentivar el rescate de esas relaciones. Se trata de un estudio de caso. Los resultados demuestran que los trastornos que resultan del uso de alcohol penalizan enormemente los miembros de la familia, contribuyendo para altos niveles de conflicto interpersonal, violencia doméstica, inadecuación parental, abuso y negligencia infantil, dificultades financieras y legales y problemas clínicos relacionados al uso del alcohol.Os problemas relacionados ao uso do álcool têm sido associados a diversos fatores, independente das causas atribuídas ao fenômeno em questão. Quando consideramos que o consumo e a dependência do

  14. [Asteroid hyalopathy. Ultrastructural study of 3 cases].

    Science.gov (United States)

    Adenis, J P; Leboutet, M J; Loubet, R

    1984-01-01

    The vitreous of three patients with asteroïd hyalosis (average age: 57 years) was obtained by a two-hand closed pars plana vitrectomy. Asteroïd hyalosis was associated with alcoholic neuropathy in the first case, long standing retinal detachment in the second case, and diabetes mellitus in the third case. The visual acuity before and after the surgical procedure improved from 1.2/6 to 6/6 in the first case, from light perception to 0.3/6 in the second case, from 0.6/6 to 4.8/6 in the third case. The vitreous was studied by different ultrastructural technics : transmission electron microscopy (T.E.M.) scanning electron microscopy (S.E.M.) and electron diffraction X ray analysis (E.D.A.X.). By S.E.M. the asteroïd bodies appeared as rounded structures with an irregular surface connected to each other by fibrous strands among sodium chloride crystals. No cellular remnants were observed. By T.E.M. the asteroïd bodies were composed of interwinned ribbons of multilaminar membranes with a periodicity (10 to 60 A) characteristic of complex lipids, especially phospholipids. At the edge of the ribbons there were dots and sometimes clumps of opaque material that tended to crack out of the specimen with the heat of the electron beam. T.E.M. study disclosed the irregular disposition of the calcific bodies. By E.D.A.X. the calcific composition of the rounded structures could be determined : calcium and phosphorus were the main elements detectable in asteroïd bodies of all sizes for all three patients. The average calcium counts for the three successive cases were : 18, 30, 43 and for phosphorus : 9, 14, 26. Potassium was found in the first case, and sulfur in the third case.(ABSTRACT TRUNCATED AT 250 WORDS)

  15. Jazz improvisers’ shared understanding: A case study

    Directory of Open Access Journals (Sweden)

    Michael F. Schober

    2014-08-01

    Full Text Available To what extent and in what arenas do collaborating musicians need to understand what they are doing in the same way? Two experienced jazz musicians who had never previously played together played three improvisations on a jazz standard (It Could Happen to You on either side of a visual barrier. They were then immediately interviewed separately about the performances, their musical intentions, and their judgments of their partner’s musical intentions, both from memory and prompted with the audiorecordings of the performances. Statements from both (audiorecorded interviews as well as statements from an expert listener were extracted and anonymized. Two months later, the performers listened to the recordings and rated the extent to which they endorsed each statement. Performers endorsed statements they themselves had generated more often than statements by their performing partner and the expert listener; their overall level of agreement with each other was greater than chance but moderate to low, with disagreements about the quality of one of the performances and about who was responsible for it. The quality of the performances combined with the disparities in agreement suggest that, at least in this case study, fully shared understanding of what happened is not essential for successful improvisation. The fact that the performers endorsed an expert listener’s statements more than their partner’s argues against a simple notion that performers’ interpretations are always privileged relative to an outsider’s.

  16. Jazz improvisers' shared understanding: a case study.

    Science.gov (United States)

    Schober, Michael F; Spiro, Neta

    2014-01-01

    To what extent and in what arenas do collaborating musicians need to understand what they are doing in the same way? Two experienced jazz musicians who had never previously played together played three improvisations on a jazz standard ("It Could Happen to You") on either side of a visual barrier. They were then immediately interviewed separately about the performances, their musical intentions, and their judgments of their partner's musical intentions, both from memory and prompted with the audiorecordings of the performances. Statements from both (audiorecorded) interviews as well as statements from an expert listener were extracted and anonymized. Two months later, the performers listened to the recordings and rated the extent to which they endorsed each statement. Performers endorsed statements they themselves had generated more often than statements by their performing partner and the expert listener; their overall level of agreement with each other was greater than chance but moderate to low, with disagreements about the quality of one of the performances and about who was responsible for it. The quality of the performances combined with the disparities in agreement suggest that, at least in this case study, fully shared understanding of what happened is not essential for successful improvisation. The fact that the performers endorsed an expert listener's statements more than their partner's argues against a simple notion that performers' interpretations are always privileged relative to an outsider's.

  17. Case study for a vaccine against leishmaniasis.

    Science.gov (United States)

    Alvar, Jorge; Croft, Simon L; Kaye, Paul; Khamesipour, Ali; Sundar, Shyam; Reed, Steven G

    2013-04-18

    Leishmaniasis in many ways offers a unique vaccine case study. Two reasons for this are that leishmaniasis is a disease complex caused by several different species of parasite that are highly related, thus raising the possibility of developing a single vaccine to protect against multiple diseases. Another reason is the demonstration that a leishmaniasis vaccine may be used therapeutically as well as prophylactically. Although there is no registered human leishmaniasis vaccine today, immunization approaches using live or killed organisms, as well as defined vaccine candidates, have demonstrated at least some degree of efficacy in humans to prevent and to treat some forms of leishmaniasis, and there is a vigorous pipeline of candidates in development. Current approaches include using individual or combined antigens of the parasite or of salivary gland extract of the parasites' insect vector, administered with or without formulation in adjuvant. Animal data obtained with several vaccine candidates are promising and some have been or will be entered into clinical testing in the near future. There is sufficient scientific and epidemiological justification to continue to invest in the development of vaccines against leishmaniasis.

  18. Hybrid Risk Management Methodology: A Case Study

    Directory of Open Access Journals (Sweden)

    Jacky Siu-Lun Ting

    2009-10-01

    Full Text Available Risk management is a decision-making process involving considerations of political, social, economic and engineering factors with relevant risk assessments relating to a potential hazard. In the last decade, a number of risk management tools are introduced and employed to manage and minimize the uncertainty and threats realization to the organizations. However, the focus of these methodologies are different; in which companies need to adopt various risk management principles to visualize a full picture of the organizational risk level. Regarding to this, this paper presents a new approach of risk management that integrates Hierarchical Holographic Modeling (HHM, Enterprise Risk Management (ERM and Business Recovery Planning (BCP for identifying and assessing risks as well as managing the consequences of realized residual risks. To illustrate the procedures of the proposed methodology, a logistic company ABC Limited is chosen to serve as a case study Through applying HHM and ERM to investigate and assess the risk, ABC Limited can be better evaluated the potential risks and then took the responsive actions (e.g. BCP to handle the risks and crisis in near future.

  19. Environmental injustice: case studies from the South

    Energy Technology Data Exchange (ETDEWEB)

    Cifuentes, Enrique [Pediatric Environmental Health Specialty Unit, National Institute of Public Health, Mexico Environmental Sciences, Av Universidad 655, Cuernavaca CP 62508 (Mexico); Frumkin, Howard [National Centre Environmental Health, Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, 1600 Clifton Road MS E-28, Atlanta, GA 30333 (United States)

    2007-10-15

    We selected three case studies to illustrate environmental injustice issues in the South. These examples relate to migrant agricultural workers, the maquiladora industry and artisanal mining, while reviewing some of the major mechanisms involved, e.g. multinational corporations, the development of free trade zones, multilateral free trade agreements and the export of hazards. A series of strategies are discussed in order to address environmental injustice and health disparities that exist on a global scale. Some of the recommendations involve policy initiatives; others, such as research and mentorship, fall within the traditional domain of public health practice. In this paper, special attention is given to concerned environmental and occupational health professionals using evidence-based data for advocacy. For lasting changes to be made, however, stronger institutions and legislation are required. Those who have the 'right to know' about environmental injustice issues include communities of concern, workers' representatives and lawyers. Government officials and company officials may eventually work on the basis of conflict resolution, compensation and remediation, to quote some examples. Systematic approaches to protect both the environment and public health must be updated.

  20. Environmental injustice: case studies from the South

    Science.gov (United States)

    Cifuentes, Enrique; Frumkin, Howard

    2007-10-01

    We selected three case studies to illustrate environmental injustice issues in the South. These examples relate to migrant agricultural workers, the maquiladora industry and artisanal mining, while reviewing some of the major mechanisms involved, e.g. multinational corporations, the development of free trade zones, multilateral free trade agreements and the export of hazards. A series of strategies are discussed in order to address environmental injustice and health disparities that exist on a global scale. Some of the recommendations involve policy initiatives; others, such as research and mentorship, fall within the traditional domain of public health practice. In this paper, special attention is given to concerned environmental and occupational health professionals using evidence-based data for advocacy. For lasting changes to be made, however, stronger institutions and legislation are required. Those who have the 'right to know' about environmental injustice issues include communities of concern, workers' representatives and lawyers. Government officials and company officials may eventually work on the basis of conflict resolution, compensation and remediation, to quote some examples. Systematic approaches to protect both the environment and public health must be updated.