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Sample records for cascades identifies small-world

  1. Efficient network reconstruction from dynamical cascades identifies small-world topology of neuronal avalanches.

    Directory of Open Access Journals (Sweden)

    Sinisa Pajevic

    2009-01-01

    Full Text Available Cascading activity is commonly found in complex systems with directed interactions such as metabolic networks, neuronal networks, or disease spreading in social networks. Substantial insight into a system's organization can be obtained by reconstructing the underlying functional network architecture from the observed activity cascades. Here we focus on Bayesian approaches and reduce their computational demands by introducing the Iterative Bayesian (IB and Posterior Weighted Averaging (PWA methods. We introduce a special case of PWA, cast in nonparametric form, which we call the normalized count (NC algorithm. NC efficiently reconstructs random and small-world functional network topologies and architectures from subcritical, critical, and supercritical cascading dynamics and yields significant improvements over commonly used correlation methods. With experimental data, NC identified a functional and structural small-world topology and its corresponding traffic in cortical networks with neuronal avalanche dynamics.

  2. Identifying Vulnerable Nodes of Complex Networks in Cascading Failures Induced by Node-Based Attacks

    Directory of Open Access Journals (Sweden)

    Shudong Li

    2013-01-01

    Full Text Available In the research on network security, distinguishing the vulnerable components of networks is very important for protecting infrastructures systems. Here, we probe how to identify the vulnerable nodes of complex networks in cascading failures, which was ignored before. Concerned with random attack (RA and highest load attack (HL on nodes, we model cascading dynamics of complex networks. Then, we introduce four kinds of weighting methods to characterize the nodes of networks including Barabási-Albert scale-free networks (SF, Watts-Strogatz small-world networks (WS, Erdos-Renyi random networks (ER, and two real-world networks. The simulations show that, for SF networks under HL attack, the nodes with small value of the fourth kind of weight are the most vulnerable and the ones with small value of the third weight are also vulnerable. Also, the real-world autonomous system with power-law distribution verifies these findings. Moreover, for WS and ER networks under both RA and HL attack, when the nodes have low tolerant ability, the ones with small value of the fourth kind of weight are more vulnerable and also the ones with high degree are easier to break down. The results give us important theoretical basis for digging the potential safety loophole and making protection strategy.

  3. DNA binding properties of the small cascade subunit Csa5.

    Directory of Open Access Journals (Sweden)

    Michael Daume

    Full Text Available CRISPR-Cas systems provide immunity against viral attacks in archaeal and bacterial cells. Type I systems employ a Cas protein complex termed Cascade, which utilizes small CRISPR RNAs to detect and degrade the exogenic DNA. A small sequence motif, the PAM, marks the foreign substrates. Previously, a recombinant type I-A Cascade complex from the archaeon Thermoproteus tenax was shown to target and degrade DNA in vitro, dependent on a native PAM sequence. Here, we present the biochemical analysis of the small subunit, Csa5, of this Cascade complex. T. tenax Csa5 preferentially bound ssDNA and mutants that showed decreased ssDNA-binding and reduced Cascade-mediated DNA cleavage were identified. Csa5 oligomerization prevented DNA binding. Specific recognition of the PAM sequence was not observed. Phylogenetic analyses identified Csa5 as a universal member of type I-A systems and revealed three distinct groups. A potential role of Csa5 in R-loop stabilization is discussed.

  4. The hepatitis C cascade of care: identifying priorities to improve clinical outcomes.

    Science.gov (United States)

    Linas, Benjamin P; Barter, Devra M; Leff, Jared A; Assoumou, Sabrina A; Salomon, Joshua A; Weinstein, Milton C; Kim, Arthur Y; Schackman, Bruce R

    2014-01-01

    As highly effective hepatitis C virus (HCV) therapies emerge, data are needed to inform the development of interventions to improve HCV treatment rates. We used simulation modeling to estimate the impact of loss to follow-up on HCV treatment outcomes and to identify intervention strategies likely to provide good value for the resources invested in them. We used a Monte Carlo state-transition model to simulate a hypothetical cohort of chronically HCV-infected individuals recently screened positive for serum HCV antibody. We simulated four hypothetical intervention strategies (linkage to care; treatment initiation; integrated case management; peer navigator) to improve HCV treatment rates, varying efficacies and costs, and identified strategies that would most likely result in the best value for the resources required for implementation. Sustained virologic responses (SVRs), life expectancy, quality-adjusted life expectancy (QALE), costs from health system and program implementation perspectives, and incremental cost-effectiveness ratios (ICERs). We estimate that imperfect follow-up reduces the real-world effectiveness of HCV therapies by approximately 75%. In the base case, a modestly effective hypothetical peer navigator program maximized the number of SVRs and QALE, with an ICER compared to the next best intervention of $48,700/quality-adjusted life year. Hypothetical interventions that simultaneously addressed multiple points along the cascade provided better outcomes and more value for money than less costly interventions targeting single steps. The 5-year program cost of the hypothetical peer navigator intervention was $14.5 million per 10,000 newly diagnosed individuals. We estimate that imperfect follow-up during the HCV cascade of care greatly reduces the real-world effectiveness of HCV therapy. Our mathematical model shows that modestly effective interventions to improve follow-up would likely be cost-effective. Priority should be given to developing and

  5. The hepatitis C cascade of care: identifying priorities to improve clinical outcomes.

    Directory of Open Access Journals (Sweden)

    Benjamin P Linas

    Full Text Available As highly effective hepatitis C virus (HCV therapies emerge, data are needed to inform the development of interventions to improve HCV treatment rates. We used simulation modeling to estimate the impact of loss to follow-up on HCV treatment outcomes and to identify intervention strategies likely to provide good value for the resources invested in them.We used a Monte Carlo state-transition model to simulate a hypothetical cohort of chronically HCV-infected individuals recently screened positive for serum HCV antibody. We simulated four hypothetical intervention strategies (linkage to care; treatment initiation; integrated case management; peer navigator to improve HCV treatment rates, varying efficacies and costs, and identified strategies that would most likely result in the best value for the resources required for implementation.Sustained virologic responses (SVRs, life expectancy, quality-adjusted life expectancy (QALE, costs from health system and program implementation perspectives, and incremental cost-effectiveness ratios (ICERs.We estimate that imperfect follow-up reduces the real-world effectiveness of HCV therapies by approximately 75%. In the base case, a modestly effective hypothetical peer navigator program maximized the number of SVRs and QALE, with an ICER compared to the next best intervention of $48,700/quality-adjusted life year. Hypothetical interventions that simultaneously addressed multiple points along the cascade provided better outcomes and more value for money than less costly interventions targeting single steps. The 5-year program cost of the hypothetical peer navigator intervention was $14.5 million per 10,000 newly diagnosed individuals.We estimate that imperfect follow-up during the HCV cascade of care greatly reduces the real-world effectiveness of HCV therapy. Our mathematical model shows that modestly effective interventions to improve follow-up would likely be cost-effective. Priority should be given to

  6. World Small Hydropower Development Report

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Heng; Esser, Lara [ICSGP (China); Masera, Diego [UNIDO, Vienna (Austria)

    2013-07-01

    Currently, small hydropower plants with a capacity of 10 MW, exist in 148 countries or territories worldwide. Four other countries have been identified with resource potential. This report aims to identify the development status and resource potential of small hydro in various countries, territories and regions throughout the world. Working with experts at the ground level to compile and share existing information, experiences and challenges, one comprehensive report was created. Decision-makers, stakeholders and potential investors clearly need this comprehensive information to more effectively promote small hydropower as a renewable and rural energy source for sustainable development and to overcome the existing development barriers. The findings of this report show that small hydropower potential globally is approximated at almost 173 GW. The figure is arrived by totaling data from a wide range of sources with potential compromise of data integrity to varying degrees. For example, research data on economically feasible potential were more readily available in developed countries than those in the least developed or developing countries. More than half of the world's known hydropower potential is located in Asia, around one third can be found in Europe and the Americas. It is possible in the future that more small hydropower potential might be identified both on the African and American continents. The installed small hydropower capacity (up to 10 MW) is estimated to be 75 GW in 2011/2012. The report provides detailed data for each country/region, including recommendations on the national, regional and international level.

  7. World Small Hydropower Development Report

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Heng; Esser, Lara (ICSGP (China)); Masera, Diego (UNIDO, Vienna (Austria))

    2013-07-01

    Currently, small hydropower plants with a capacity of 10 MW, exist in 148 countries or territories worldwide. Four other countries have been identified with resource potential. This report aims to identify the development status and resource potential of small hydro in various countries, territories and regions throughout the world. Working with experts at the ground level to compile and share existing information, experiences and challenges, one comprehensive report was created. Decision-makers, stakeholders and potential investors clearly need this comprehensive information to more effectively promote small hydropower as a renewable and rural energy source for sustainable development and to overcome the existing development barriers. The findings of this report show that small hydropower potential globally is approximated at almost 173 GW. The figure is arrived by totaling data from a wide range of sources with potential compromise of data integrity to varying degrees. For example, research data on economically feasible potential were more readily available in developed countries than those in the least developed or developing countries. More than half of the world's known hydropower potential is located in Asia, around one third can be found in Europe and the Americas. It is possible in the future that more small hydropower potential might be identified both on the African and American continents. The installed small hydropower capacity (up to 10 MW) is estimated to be 75 GW in 2011/2012. The report provides detailed data for each country/region, including recommendations on the national, regional and international level.

  8. A comparison of methods for cascade prediction

    OpenAIRE

    Guo, Ruocheng; Shakarian, Paulo

    2016-01-01

    Information cascades exist in a wide variety of platforms on Internet. A very important real-world problem is to identify which information cascades can go viral. A system addressing this problem can be used in a variety of applications including public health, marketing and counter-terrorism. As a cascade can be considered as compound of the social network and the time series. However, in related literature where methods for solving the cascade prediction problem were proposed, the experimen...

  9. A dynamical characterization of the small world phase

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, Tanya; Vilela Mendes, R.; Seixas, Joao

    2003-12-08

    Small-world (SW) networks have been identified in many different fields. Topological coefficients like the clustering coefficient and the characteristic path length have been used in the past for a qualitative characterization of these networks. Here a dynamical approach is used to characterize the small-world phenomenon. Using the Watts-Strogatz {beta}-model, a coupled map dynamical system is defined on the network. Entrance to and exit from the SW phase are related to the behavior of the ergodic invariants of the dynamics.

  10. A dynamical characterization of the small world phase

    International Nuclear Information System (INIS)

    Araujo, Tanya; Vilela Mendes, R.; Seixas, Joao

    2003-01-01

    Small-world (SW) networks have been identified in many different fields. Topological coefficients like the clustering coefficient and the characteristic path length have been used in the past for a qualitative characterization of these networks. Here a dynamical approach is used to characterize the small-world phenomenon. Using the Watts-Strogatz β-model, a coupled map dynamical system is defined on the network. Entrance to and exit from the SW phase are related to the behavior of the ergodic invariants of the dynamics

  11. Brain networks: small-worlds, after all?

    International Nuclear Information System (INIS)

    Muller, Lyle; Destexhe, Alain; Rudolph-Lilith, Michelle

    2014-01-01

    Since its introduction, the ‘small-world’ effect has played a central role in network science, particularly in the analysis of the complex networks of the nervous system. From the cellular level to that of interconnected cortical regions, many analyses have revealed small-world properties in the networks of the brain. In this work, we revisit the quantification of small-worldness in neural graphs. We find that neural graphs fall into the ‘borderline’ regime of small-worldness, residing close to that of a random graph, especially when the degree sequence of the network is taken into account. We then apply recently introducted analytical expressions for clustering and distance measures, to study this borderline small-worldness regime. We derive theoretical bounds for the minimal and maximal small-worldness index for a given graph, and by semi-analytical means, study the small-worldness index itself. With this approach, we find that graphs with small-worldness equivalent to that observed in experimental data are dominated by their random component. These results provide the first thorough analysis suggesting that neural graphs may reside far away from the maximally small-world regime. (paper)

  12. Brain networks: small-worlds, after all?

    Energy Technology Data Exchange (ETDEWEB)

    Muller, Lyle; Destexhe, Alain; Rudolph-Lilith, Michelle [Unité de Neurosciences, Information et Complexité (UNIC), Centre National de la Recherche Scientifique (CNRS), 1 Avenue de la Terrasse, Gif-sur-Yvette (France)

    2014-10-01

    Since its introduction, the ‘small-world’ effect has played a central role in network science, particularly in the analysis of the complex networks of the nervous system. From the cellular level to that of interconnected cortical regions, many analyses have revealed small-world properties in the networks of the brain. In this work, we revisit the quantification of small-worldness in neural graphs. We find that neural graphs fall into the ‘borderline’ regime of small-worldness, residing close to that of a random graph, especially when the degree sequence of the network is taken into account. We then apply recently introducted analytical expressions for clustering and distance measures, to study this borderline small-worldness regime. We derive theoretical bounds for the minimal and maximal small-worldness index for a given graph, and by semi-analytical means, study the small-worldness index itself. With this approach, we find that graphs with small-worldness equivalent to that observed in experimental data are dominated by their random component. These results provide the first thorough analysis suggesting that neural graphs may reside far away from the maximally small-world regime. (paper)

  13. The Academic Life: Small Worlds, Different Worlds

    Science.gov (United States)

    Locke, William

    2010-01-01

    "The Academic Life: Small Worlds, Different Worlds" represented an impressive investigation of the largest and most complex national academic community in the world, which seriously attempted a detailed representation of the variations in its form. Its ethnographic orientation to understanding the internal academic life through exploratory…

  14. A novel Direct Small World network model

    Directory of Open Access Journals (Sweden)

    LIN Tao

    2016-10-01

    Full Text Available There is a certain degree of redundancy and low efficiency of existing computer networks.This paper presents a novel Direct Small World network model in order to optimize networks.In this model,several nodes construct a regular network.Then,randomly choose and replot some nodes to generate Direct Small World network iteratively.There is no change in average distance and clustering coefficient.However,the network performance,such as hops,is improved.The experiments prove that compared to traditional small world network,the degree,average of degree centrality and average of closeness centrality are lower in Direct Small World network.This illustrates that the nodes in Direct Small World networks are closer than Watts-Strogatz small world network model.The Direct Small World can be used not only in the communication of the community information,but also in the research of epidemics.

  15. Epidemics in interconnected small-world networks.

    Science.gov (United States)

    Liu, Meng; Li, Daqing; Qin, Pengju; Liu, Chaoran; Wang, Huijuan; Wang, Feilong

    2015-01-01

    Networks can be used to describe the interconnections among individuals, which play an important role in the spread of disease. Although the small-world effect has been found to have a significant impact on epidemics in single networks, the small-world effect on epidemics in interconnected networks has rarely been considered. Here, we study the susceptible-infected-susceptible (SIS) model of epidemic spreading in a system comprising two interconnected small-world networks. We find that the epidemic threshold in such networks decreases when the rewiring probability of the component small-world networks increases. When the infection rate is low, the rewiring probability affects the global steady-state infection density, whereas when the infection rate is high, the infection density is insensitive to the rewiring probability. Moreover, epidemics in interconnected small-world networks are found to spread at different velocities that depend on the rewiring probability.

  16. Epidemics in interconnected small-world networks.

    Directory of Open Access Journals (Sweden)

    Meng Liu

    Full Text Available Networks can be used to describe the interconnections among individuals, which play an important role in the spread of disease. Although the small-world effect has been found to have a significant impact on epidemics in single networks, the small-world effect on epidemics in interconnected networks has rarely been considered. Here, we study the susceptible-infected-susceptible (SIS model of epidemic spreading in a system comprising two interconnected small-world networks. We find that the epidemic threshold in such networks decreases when the rewiring probability of the component small-world networks increases. When the infection rate is low, the rewiring probability affects the global steady-state infection density, whereas when the infection rate is high, the infection density is insensitive to the rewiring probability. Moreover, epidemics in interconnected small-world networks are found to spread at different velocities that depend on the rewiring probability.

  17. Epidemics in interconnected small-world networks

    NARCIS (Netherlands)

    Liu, M.; Li, D.; Qin, P.; Liu, C.; Wang, H.; Wang, F.

    2015-01-01

    Networks can be used to describe the interconnections among individuals, which play an important role in the spread of disease. Although the small-world effect has been found to have a significant impact on epidemics in single networks, the small-world effect on epidemics in interconnected networks

  18. Risk and Resilience Analysis of Complex Network Systems Considering Cascading Failure and Recovery Strategy Based on Coupled Map Lattices

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    Fuchun Ren

    2015-01-01

    Full Text Available Risk and resilience are important and challenging issues in complex network systems since a single failure may trigger a whole collapse of the systems due to cascading effect. New theories, models, and methods are urgently demanded to deal with this challenge. In this paper, a coupled map lattices (CML based approach is adopted to analyze the risk of cascading process in Watts-Strogatz (WS small-world network and Barabási and Albert (BA scale-free network, respectively. Then, to achieve an effective and robust system and provide guidance in countering the cascading failure, a modified CML model with recovery strategy factor is proposed. Numerical simulations are put forward based on small-world CML and scale-free CML. The simulation results reveal that appropriate recovery strategies would significantly improve the resilience of networks.

  19. Algebraic approach to small-world network models

    Science.gov (United States)

    Rudolph-Lilith, Michelle; Muller, Lyle E.

    2014-01-01

    We introduce an analytic model for directed Watts-Strogatz small-world graphs and deduce an algebraic expression of its defining adjacency matrix. The latter is then used to calculate the small-world digraph's asymmetry index and clustering coefficient in an analytically exact fashion, valid nonasymptotically for all graph sizes. The proposed approach is general and can be applied to all algebraically well-defined graph-theoretical measures, thus allowing for an analytical investigation of finite-size small-world graphs.

  20. Scaling in small-world resistor networks

    International Nuclear Information System (INIS)

    Korniss, G.; Hastings, M.B.; Bassler, K.E.; Berryman, M.J.; Kozma, B.; Abbott, D.

    2006-01-01

    We study the effective resistance of small-world resistor networks. Utilizing recent analytic results for the propagator of the Edwards-Wilkinson process on small-world networks, we obtain the asymptotic behavior of the disorder-averaged two-point resistance in the large system-size limit. We find that the small-world structure suppresses large network resistances: both the average resistance and its standard deviation approaches a finite value in the large system-size limit for any non-zero density of random links. We also consider a scenario where the link conductance decays as a power of the length of the random links, l -α . In this case we find that the average effective system resistance diverges for any non-zero value of α

  1. Dawn of small worlds dwarf planets, asteroids, comets

    CERN Document Server

    Moltenbrey, Michael

    2016-01-01

    This book gives a detailed introduction to the thousands and thousands of smaller bodies in the solar system. Written for interested laymen, amateur astronomers and students it describes the nature and origin of asteroids, dwarf planets and comets, and gives detailed information about their role in the solar system. The author nicely reviews the history of small-world-exploration and describes past, current and future space craft missions studying small worlds, and presents their results. Readers will learn that small solar system worlds have a dramatically different nature and appearance than the planets. Even though research activity on small worlds has increased in the recent past many of their properties are still in the dark and need further research.

  2. Hierarchical regular small-world networks

    International Nuclear Information System (INIS)

    Boettcher, Stefan; Goncalves, Bruno; Guclu, Hasan

    2008-01-01

    Two new networks are introduced that resemble small-world properties. These networks are recursively constructed but retain a fixed, regular degree. They possess a unique one-dimensional lattice backbone overlaid by a hierarchical sequence of long-distance links, mixing real-space and small-world features. Both networks, one 3-regular and the other 4-regular, lead to distinct behaviors, as revealed by renormalization group studies. The 3-regular network is planar, has a diameter growing as √N with system size N, and leads to super-diffusion with an exact, anomalous exponent d w = 1.306..., but possesses only a trivial fixed point T c = 0 for the Ising ferromagnet. In turn, the 4-regular network is non-planar, has a diameter growing as ∼2 √(log 2 N 2 ) , exhibits 'ballistic' diffusion (d w = 1), and a non-trivial ferromagnetic transition, T c > 0. It suggests that the 3-regular network is still quite 'geometric', while the 4-regular network qualifies as a true small world with mean-field properties. As an engineering application we discuss synchronization of processors on these networks. (fast track communication)

  3. An Investigation of the Differences and Similarities between Generated Small-World Networks for Right- and Left-Hand Motor Imageries.

    Science.gov (United States)

    Zhang, Jiang; Li, Yuyao; Chen, Huafu; Ding, Jurong; Yuan, Zhen

    2016-11-04

    In this study, small-world network analysis was performed to identify the similarities and differences between functional brain networks for right- and left-hand motor imageries (MIs). First, Pearson correlation coefficients among the nodes within the functional brain networks from healthy subjects were calculated. Then, small-world network indicators, including the clustering coefficient, the average path length, the global efficiency, the local efficiency, the average node degree, and the small-world index, were generated for the functional brain networks during both right- and left-hand MIs. We identified large differences in the small-world network indicators between the functional networks during MI and in the random networks. More importantly, the functional brain networks underlying the right- and left-hand MIs exhibited similar small-world properties in terms of the clustering coefficient, the average path length, the global efficiency, and the local efficiency. By contrast, the right- and left-hand MI brain networks showed differences in small-world characteristics, including indicators such as the average node degree and the small-world index. Interestingly, our findings also suggested that the differences in the activity intensity and range, the average node degree, and the small-world index of brain networks between the right- and left-hand MIs were associated with the asymmetry of brain functions.

  4. Statistical complexity is maximized in a small-world brain.

    Directory of Open Access Journals (Sweden)

    Teck Liang Tan

    Full Text Available In this paper, we study a network of Izhikevich neurons to explore what it means for a brain to be at the edge of chaos. To do so, we first constructed the phase diagram of a single Izhikevich excitatory neuron, and identified a small region of the parameter space where we find a large number of phase boundaries to serve as our edge of chaos. We then couple the outputs of these neurons directly to the parameters of other neurons, so that the neuron dynamics can drive transitions from one phase to another on an artificial energy landscape. Finally, we measure the statistical complexity of the parameter time series, while the network is tuned from a regular network to a random network using the Watts-Strogatz rewiring algorithm. We find that the statistical complexity of the parameter dynamics is maximized when the neuron network is most small-world-like. Our results suggest that the small-world architecture of neuron connections in brains is not accidental, but may be related to the information processing that they do.

  5. Multiobjective Bak-Sneppen model on a small-world network

    International Nuclear Information System (INIS)

    Elettreby, M.F.

    2005-01-01

    Small-world networks (SWN) are relevant to biological systems. We study the dynamics of the Bak-Sneppen (BS) model on small-world network, including the concepts of extremal dynamics, multiobjective optimization and coherent noise. We find that the small-world structure stabilizes the system. Also, it is more realistic to augment the Bak-Sneppen model by these concepts

  6. Multiobjective Bak-Sneppen model on a small-world network

    International Nuclear Information System (INIS)

    Elettreby, M.

    2004-09-01

    Small-world networks (SWN) are relevant to biological systems. We study the dynamics of the Bak-Sneppen (BS) model on small-world network, including the concepts of extremal dynamics, multiobjective optimization and coherent noise. We find that the small-world structure stabilizes the system. Also, it is more realistic to augment the Bak-Sneppen model by these concepts. (author)

  7. Ecological footprint analysis of environmental impacts by cascaded exploitation of diversion-type small hydropower: a case study in southwest china

    Science.gov (United States)

    Wang, Zhenhua; Li, Qingyun; Huang, Zhuo; Tang, Xianqiang; Zhao, Weihua

    2017-05-01

    Cascaded exploitation of diversion-type small hydropower (SHP) offers a source of new energy as well as socioeconomic benefits; however, it inevitably causes environmental disturbance and damage. Previous studies on the cumulative effect of cascaded diversion SHP rarely discussed using quantitative analysis method. In this paper, the ecological footprint analysis approach is proposed to assess the positive and negative impacts of cascaded diversion SHP on environment of a small-scale river in Southwest China. Positive impact is defined as ecological supply footprint (ESF), which refers to vegetation protection by replacing firewood with SHP. Negative impact is defined as ecological loss footprint (ELF), which includes fish and net primary productivity loss, vegetation destruction and soil erosion. With the raising in the number (n>4) of diversion SHP stations, the difference between ELF and ESF increases remarkably, suggesting that the adverse impacts of cascaded diversion SHP accumulate in the study area. Compared with vegetation destruction and soil erosion, the cumulative loss of fish and net productivity is the most important aspect of the adverse impacts which needs more attentions.

  8. Failure cascade in interdependent network with traffic loads

    International Nuclear Information System (INIS)

    Hong, Sheng; Wang, Baoqing; Wang, Jianghui; Zhao, Tingdi; Ma, Xiaomin

    2015-01-01

    Complex networks have been widely studied recent years, but most researches focus on the single, non-interacting networks. With the development of modern systems, many infrastructure networks are coupled together and therefore should be modeled as interdependent networks. For interdependent networks, failure of nodes in one network may lead to failure of dependent nodes in the other networks. This may happen recursively and lead to a failure cascade. In the real world, different networks carry different traffic loads. Overload and load redistribution may lead to more nodes’ failure. Considering the dependency between the interdependent networks and the traffic load, a small fraction of fault nodes may lead to complete fragmentation of a system. Based on the robust analysis of interdependent networks, we propose a costless defense strategy to suppress the failure cascade. Our findings highlight the need to consider the load and coupling preference when designing robust interdependent networks. And it is necessary to take actions in the early stage of the failure cascade to decrease the losses caused by the large-scale breakdown of infrastructure networks. (paper)

  9. Stability of cascade search

    Energy Technology Data Exchange (ETDEWEB)

    Fomenko, Tatiana N [M. V. Lomonosov Moscow State University, Faculty of Computational Mathematics and Cybernetics, Moscow (Russian Federation)

    2010-10-22

    We find sufficient conditions on a searching multi-cascade for a modification of the set of limit points of the cascade that satisfy an assessing inequality for the distance from each of these points to the initial point to be small, provided that the modifications of the initial point and the initial set-valued functionals or maps used to construct the multi-cascade are small. Using this result, we prove the stability (in the above sense) of the cascade search for the set of common pre-images of a closed subspace under the action of n set-valued maps, n{>=}1 (in particular, for the set of common roots of these maps and for the set of their coincidences). For n=2 we obtain generalizations of some results of A. V. Arutyunov; the very statement of the problem comes from a recent paper of his devoted to the study of the stability of the subset of coincidences of a Lipschitz map and a covering map.

  10. Optimal network structure to induce the maximal small-world effect

    International Nuclear Information System (INIS)

    Zhang Zheng-Zhen; Xu Wen-Jun; Lin Jia-Ru; Zeng Shang-You

    2014-01-01

    In this paper, the general efficiency, which is the average of the global efficiency and the local efficiency, is defined to measure the communication efficiency of a network. The increasing ratio of the general efficiency of a small-world network relative to that of the corresponding regular network is used to measure the small-world effect quantitatively. The more considerable the small-world effect, the higher the general efficiency of a network with a certain cost is. It is shown that the small-world effect increases monotonically with the increase of the vertex number. The optimal rewiring probability to induce the best small-world effect is approximately 0.02 and the optimal average connection probability decreases monotonically with the increase of the vertex number. Therefore, the optimal network structure to induce the maximal small-world effect is the structure with the large vertex number (> 500), the small rewiring probability (≍ 0.02) and the small average connection probability (< 0.1). Many previous research results support our results. (interdisciplinary physics and related areas of science and technology)

  11. Searching in small-world networks

    International Nuclear Information System (INIS)

    Moura, Alessandro P.S. de; Motter, Adilson E.; Grebogi, Celso

    2003-01-01

    We study the average time it takes to find a desired node in the Watts-Strogatz family of networks. We consider the case when the look-up time can be neglected and when it is important, where the look-up time is the time needed to choose one among all the neighboring nodes of a node at each step in the search. We show that in both cases, the search time is minimum in the small-world regime, when an appropriate distance between the nodes is defined. Through an analytical model, we show that the search time scales as N 1/D(D+1) for small-world networks, where N is the number of nodes and D is the dimension of the underlying lattice. This model is shown to be in agreement with numerical simulations

  12. Contingency Analysis of Cascading Line Outage Events

    Energy Technology Data Exchange (ETDEWEB)

    Thomas L Baldwin; Magdy S Tawfik; Miles McQueen

    2011-03-01

    As the US power systems continue to increase in size and complexity, including the growth of smart grids, larger blackouts due to cascading outages become more likely. Grid congestion is often associated with a cascading collapse leading to a major blackout. Such a collapse is characterized by a self-sustaining sequence of line outages followed by a topology breakup of the network. This paper addresses the implementation and testing of a process for N-k contingency analysis and sequential cascading outage simulation in order to identify potential cascading modes. A modeling approach described in this paper offers a unique capability to identify initiating events that may lead to cascading outages. It predicts the development of cascading events by identifying and visualizing potential cascading tiers. The proposed approach was implemented using a 328-bus simplified SERC power system network. The results of the study indicate that initiating events and possible cascading chains may be identified, ranked and visualized. This approach may be used to improve the reliability of a transmission grid and reduce its vulnerability to cascading outages.

  13. Immunizations on small worlds of tree-based wireless sensor networks

    International Nuclear Information System (INIS)

    Li Qiao; Zhang Bai-Hai; Cui Ling-Guo; Fan Zhun; Vasilakos Athanasios, V.

    2012-01-01

    The sensor virus is a serious threat, as an attacker can simply send a single packet to compromise the entire sensor network. Epidemics become drastic with link additions among sensors when the small world phenomena occur. Two immunization strategies, uniform immunization and temporary immunization, are conducted on small worlds of tree-based wireless sensor networks to combat the sensor viruses. With the former strategy, the infection extends exponentially, although the immunization effectively reduces the contagion speed. With the latter strategy, recurrent contagion oscillations occur in the small world when the spatial-temporal dynamics of the epidemic are considered. The oscillations come from the small-world structure and the temporary immunization. Mathematical analyses on the small world of the Cayley tree are presented to reveal the epidemic dynamics with the two immunization strategies. (general)

  14. Cascade Probability Control to Mitigate Bufferbloat under Multiple Real-World TCP Stacks

    Directory of Open Access Journals (Sweden)

    Hoang-Linh To

    2015-01-01

    Full Text Available Persistently full buffer problem, commonly known as bufferbloat, causes unnecessary additional latency and throughput degradation whenever congestion happens in Internet. Several proposed queue management schemes, with the debloat mission, are almost based on the modification of one-loop feedback control where the instability and bad transient behavior are still big challenges. In this paper, we present a cascade probability control scheme using margin optimal method to address such challenges under different kinds of real-world TCP stacks. Simulation results guarantee the measured round trip time tracking to a low value of delay (e.g., ≈180 ms under TCP Reno, and ≈130 ms under TCP Cubic and ≈50% delay reduction in comparison to current deployed queue management schemes in network devices.

  15. Small Worlds and Cultural Polarization

    NARCIS (Netherlands)

    Flache, Andreas; Macy, Michael W.

    2011-01-01

    Building on Granovetter's theory of the "strength of weak ties,'' research on "small-world'' networks suggests that bridges between clusters in a social network (long-range ties) promote cultural diffusion, homogeneity, and integration. We show that this macro-level implication of network structure

  16. Energy cascades in Canada

    Energy Technology Data Exchange (ETDEWEB)

    Hayden, A. C.; Brown, T. D.

    1979-03-15

    Combining energy uses in a cascade can result in significant overall reductions in fuel requirements. The simplest applications for a cascade are in the recovery of waste heat from existing processes using special boilers or turbines. Specific applications of more-complex energy cascades for Canada are discussed. A combined-cycle plant at a chemical refinery in Ontario is world leader in energy efficiency. Total-energy systems for commercial buildings, such as one installed in a school in Western Canada, offer attractive energy and operating cost benefits. A cogeneration plant proposed for the National Capital Region, generating electricity as well as steam for district heating, allows the use of a low-grade fossil fuel (coal), greatly improves energy-transformation efficiency, and also utilizes an effectively renewable resource (municipal garbage). Despite the widespread availability of equipment and technology of energy cascades, the sale of steam and electricity across plant boundaries presents a barrier. More widespread use of cascades will require increased cooperation among industry, electric utilities and the various levels of government if Canada is to realize the high levels of energy efficiency potential available.

  17. Stability of a neural network model with small-world connections

    International Nuclear Information System (INIS)

    Li Chunguang; Chen Guanrong

    2003-01-01

    Small-world networks are highly clustered networks with small distances among the nodes. There are many biological neural networks that present this kind of connection. There are no special weightings in the connections of most existing small-world network models. However, this kind of simply connected model cannot characterize biological neural networks, in which there are different weights in synaptic connections. In this paper, we present a neural network model with weighted small-world connections and further investigate the stability of this model

  18. Antibiotic discovery throughout the Small World Initiative: A molecular strategy to identify biosynthetic gene clusters involved in antagonistic activity.

    Science.gov (United States)

    Davis, Elizabeth; Sloan, Tyler; Aurelius, Krista; Barbour, Angela; Bodey, Elijah; Clark, Brigette; Dennis, Celeste; Drown, Rachel; Fleming, Megan; Humbert, Allison; Glasgo, Elizabeth; Kerns, Trent; Lingro, Kelly; McMillin, MacKenzie; Meyer, Aaron; Pope, Breanna; Stalevicz, April; Steffen, Brittney; Steindl, Austin; Williams, Carolyn; Wimberley, Carmen; Zenas, Robert; Butela, Kristen; Wildschutte, Hans

    2017-06-01

    The emergence of bacterial pathogens resistant to all known antibiotics is a global health crisis. Adding to this problem is that major pharmaceutical companies have shifted away from antibiotic discovery due to low profitability. As a result, the pipeline of new antibiotics is essentially dry and many bacteria now resist the effects of most commonly used drugs. To address this global health concern, citizen science through the Small World Initiative (SWI) was formed in 2012. As part of SWI, students isolate bacteria from their local environments, characterize the strains, and assay for antibiotic production. During the 2015 fall semester at Bowling Green State University, students isolated 77 soil-derived bacteria and genetically characterized strains using the 16S rRNA gene, identified strains exhibiting antagonistic activity, and performed an expanded SWI workflow using transposon mutagenesis to identify a biosynthetic gene cluster involved in toxigenic compound production. We identified one mutant with loss of antagonistic activity and through subsequent whole-genome sequencing and linker-mediated PCR identified a 24.9 kb biosynthetic gene locus likely involved in inhibitory activity in that mutant. Further assessment against human pathogens demonstrated the inhibition of Bacillus cereus, Listeria monocytogenes, and methicillin-resistant Staphylococcus aureus in the presence of this compound, thus supporting our molecular strategy as an effective research pipeline for SWI antibiotic discovery and genetic characterization. © 2017 The Authors. MicrobiologyOpen published by John Wiley & Sons Ltd.

  19. The Efficiency of a Small-World Functional Brain Network

    Institute of Scientific and Technical Information of China (English)

    ZHAO Qing-Bai; ZHANG Xiao-Fei; SUI Dan-Ni; ZHOU Zhi-Jin; CHEN Qi-Cai; TANG Yi-Yuan

    2012-01-01

    We investigate whether the small-world topology of a functional brain network means high information processing efficiency by calculating the correlation between the small-world measures of a functional brain network and behavioral reaction during an imagery task.Functional brain networks are constructed by multichannel eventrelated potential data,in which the electrodes are the nodes and the functional connectivities between them are the edges.The results show that the correlation between small-world measures and reaction time is task-specific,such that in global imagery,there is a positive correlation between the clustering coefficient and reaction time,while in local imagery the average path length is positively correlated with the reaction time.This suggests that the efficiency of a functional brain network is task-dependent.%We investigate whether the small-world topology of a functional brain network means high information processing efficiency by calculating the correlation between the small-world measures of a functional brain network and behavioral reaction during an imagery task. Functional brain networks are constructed by multichannel event-related potential data, in which the electrodes are the nodes and the functional connectivities between them are the edges. The results show that the correlation between small-world measures and reaction time is task-specific, such that in global imagery, there is a positive correlation between the clustering coefficient and reaction time, while in local imagery the average path length is positively correlated with the reaction time. This suggests that the efficiency of a functional brain network is task-dependent.

  20. Can recurrence networks show small-world property?

    International Nuclear Information System (INIS)

    Jacob, Rinku; Harikrishnan, K.P.; Misra, R.; Ambika, G.

    2016-01-01

    Recurrence networks are complex networks, constructed from time series data, having several practical applications. Though their properties when constructed with the threshold value ϵ chosen at or just above the percolation threshold of the network are quite well understood, what happens as the threshold increases beyond the usual operational window is still not clear from a complex network perspective. The present Letter is focused mainly on the network properties at intermediate-to-large values of the recurrence threshold, for which no systematic study has been performed so far. We argue, with numerical support, that recurrence networks constructed from chaotic attractors with ϵ equal to the usual recurrence threshold or slightly above cannot, in general, show small-world property. However, if the threshold is further increased, the recurrence network topology initially changes to a small-world structure and finally to that of a classical random graph as the threshold approaches the size of the strange attractor. - Highlights: • Properties of recurrence networks at intermediate-to-large values of recurrence threshold are analyzed from a complex network perspective. • Using a combined plot of characteristic path length and clustering coefficient, it is shown that the recurrence network constructed with recurrence threshold equal to or just above the percolation threshold cannot, in general, display small-world property. • As the recurrence threshold is increased from its usual operational window, the resulting network makes a smooth transition initially to a small-world network for an intermediate range of thresholds and finally to the classical random graph as the threshold becomes comparable to the size of the attractor.

  1. Can recurrence networks show small-world property?

    Energy Technology Data Exchange (ETDEWEB)

    Jacob, Rinku, E-mail: rinku.jacob.vallanat@gmail.com [Department of Physics, The Cochin College, Cochin, 682002 (India); Harikrishnan, K.P., E-mail: kp_hk2002@yahoo.co.in [Department of Physics, The Cochin College, Cochin, 682002 (India); Misra, R., E-mail: rmisra@iucaa.in [Inter University Centre for Astronomy and Astrophysics, Pune, 411007 (India); Ambika, G., E-mail: g.ambika@iiserpune.ac.in [Indian Institute of Science Education and Research, Pune, 411008 (India)

    2016-08-12

    Recurrence networks are complex networks, constructed from time series data, having several practical applications. Though their properties when constructed with the threshold value ϵ chosen at or just above the percolation threshold of the network are quite well understood, what happens as the threshold increases beyond the usual operational window is still not clear from a complex network perspective. The present Letter is focused mainly on the network properties at intermediate-to-large values of the recurrence threshold, for which no systematic study has been performed so far. We argue, with numerical support, that recurrence networks constructed from chaotic attractors with ϵ equal to the usual recurrence threshold or slightly above cannot, in general, show small-world property. However, if the threshold is further increased, the recurrence network topology initially changes to a small-world structure and finally to that of a classical random graph as the threshold approaches the size of the strange attractor. - Highlights: • Properties of recurrence networks at intermediate-to-large values of recurrence threshold are analyzed from a complex network perspective. • Using a combined plot of characteristic path length and clustering coefficient, it is shown that the recurrence network constructed with recurrence threshold equal to or just above the percolation threshold cannot, in general, display small-world property. • As the recurrence threshold is increased from its usual operational window, the resulting network makes a smooth transition initially to a small-world network for an intermediate range of thresholds and finally to the classical random graph as the threshold becomes comparable to the size of the attractor.

  2. A simple model of global cascades on random networks

    Science.gov (United States)

    Watts, Duncan J.

    2002-04-01

    The origin of large but rare cascades that are triggered by small initial shocks is a phenomenon that manifests itself as diversely as cultural fads, collective action, the diffusion of norms and innovations, and cascading failures in infrastructure and organizational networks. This paper presents a possible explanation of this phenomenon in terms of a sparse, random network of interacting agents whose decisions are determined by the actions of their neighbors according to a simple threshold rule. Two regimes are identified in which the network is susceptible to very large cascadesherein called global cascadesthat occur very rarely. When cascade propagation is limited by the connectivity of the network, a power law distribution of cascade sizes is observed, analogous to the cluster size distribution in standard percolation theory and avalanches in self-organized criticality. But when the network is highly connected, cascade propagation is limited instead by the local stability of the nodes themselves, and the size distribution of cascades is bimodal, implying a more extreme kind of instability that is correspondingly harder to anticipate. In the first regime, where the distribution of network neighbors is highly skewed, it is found that the most connected nodes are far more likely than average nodes to trigger cascades, but not in the second regime. Finally, it is shown that heterogeneity plays an ambiguous role in determining a system's stability: increasingly heterogeneous thresholds make the system more vulnerable to global cascades; but an increasingly heterogeneous degree distribution makes it less vulnerable.

  3. Small Worlds Week: Raising Curiosity and Contributing to STEM

    Science.gov (United States)

    Ng, C.; Mayo, L.; Stephenson, B. E.; Keck, A.; Cline, T. D.; Lewis, E. M.

    2015-12-01

    Dwarf planets, comets, asteroids, and icy moons took center stage in the years 2014-2015 as multiple spacecraft (New Horizons, Dawn, Rosetta, Cassini) and ground-based observing campaigns observed these small and yet amazing celestial bodies. Just prior to the historic New Horizons encounter with the Pluto system, NASA celebrated Small Worlds Week (July 6-10) as a fully online program to highlight small worlds mission discoveries. Small Worlds Week leveraged the infrastructure of Sun-Earth Days that included a robust web design, exemplary education materials, hands-on fun activities, multimedia resources, science and career highlights, and a culminating event. Each day from July 6-9, a new class of solar system small worlds was featured on the website: Monday-comets, Tuesday-asteroids, Wednesday-icy moons, and Thursday-dwarf planets. Then on Friday, July 10, nine scientists from Goddard Space Flight Center, Jet Propulsion Laboratory, Naval Research Laboratory, and Lunar and Planetary Institute gathered online for four hours to answer questions from the public via Facebook and Twitter. Throughout the afternoon the scientists worked closely with a social media expert and several summer interns to reply to inquirers and to archive their chats. By all accounts, Small Worlds Week was a huge success. The group plans to improve and replicate the program during the school year with a more classroom focus, and then to build and extend the program to be held every year. For more information, visit http:// sunearthday.nasa.gov or catch us on Twitter, #nasasww.

  4. Exploring the story, science, and adventure of small worlds

    Science.gov (United States)

    Swann, J. L.; Elkins-Tanton, L. T.; Anbar, A. D.; Klug Boonstra, S.; Tamer, A. J.; Mead, C.; Hunsley, D.

    2017-12-01

    Small worlds are a strategic focus at NASA, reflected by missions such as Osiris Rex and Psyche among others. The Infiniscope project, with funding from NASA SMD, is building on this scientific and public interest to teach formal and informal learners about asteroids and other small worlds. The digital learning experience, "Where are the small worlds?", and future Infiniscope experiences, incorporate a design theory that we describe as "education through exploration" (ETX) which is provided through an adaptive e-learning platform. This design ensures that learners actively engage in exploration and discovery, while receiving targeted feedback to push through challenges. To ensure that this and future experiences reach and meet the needs of as many educators as possible, Infiniscope includes a digital teaching network to host the experiences and support the reuse and adaptation of digital resources in new lessons. "Where are the small worlds?" puts learners in an interactive simulation of the solar system and provides a mission structure in which they hunt for "astrocaches" on near earth objects, main belt asteroids, and Kuiper-belt objects. These activities allow the learner to discover the locations of the small worlds in the solar system and develop an intuitive understanding for the relative motion of objects at various distances from the Sun. The experience is NGSS-aligned and accompanied by a lesson plan for integration into the classroom. In testing with more than 500 middle-school students, 83% of participants said they wanted to do more experiences like "Where are the small worlds?" They also found the experience both "fun" and "interesting" while being moderately difficult. "Where are the small worlds?" is one of many visualizations and lessons that is available within the Infiniscope teaching network. The network already has hundreds of members and is expected to grow in both numbers and engagement over time. Currently, educators can search and use pre

  5. Analysis on Invulnerability of Wireless Sensor Network towards Cascading Failures Based on Coupled Map Lattice

    Directory of Open Access Journals (Sweden)

    Xiuwen Fu

    2018-01-01

    Full Text Available Previous research of wireless sensor networks (WSNs invulnerability mainly focuses on the static topology, while ignoring the cascading process of the network caused by the dynamic changes of load. Therefore, given the realistic features of WSNs, in this paper we research the invulnerability of WSNs with respect to cascading failures based on the coupled map lattice (CML. The invulnerability and the cascading process of four types of network topologies (i.e., random network, small-world network, homogenous scale-free network, and heterogeneous scale-free network under various attack schemes (i.e., random attack, max-degree attack, and max-status attack are investigated, respectively. The simulation results demonstrate that the rise of interference R and coupling coefficient ε will increase the risks of cascading failures. Cascading threshold values Rc and εc exist, where cascading failures will spread to the entire network when R>Rc or ε>εc. When facing a random attack or max-status attack, the network with higher heterogeneity tends to have a stronger invulnerability towards cascading failures. Conversely, when facing a max-degree attack, the network with higher uniformity tends to have a better performance. Besides that, we have also proved that the spreading speed of cascading failures is inversely proportional to the average path length of the network and the increase of average degree k can improve the network invulnerability.

  6. Local stability and Hopf bifurcation in small-world delayed networks

    International Nuclear Information System (INIS)

    Li Chunguang; Chen Guanrong

    2004-01-01

    The notion of small-world networks, recently introduced by Watts and Strogatz, has attracted increasing interest in studying the interesting properties of complex networks. Notice that, a signal or influence travelling on a small-world network often is associated with time-delay features, which are very common in biological and physical networks. Also, the interactions within nodes in a small-world network are often nonlinear. In this paper, we consider a small-world networks model with nonlinear interactions and time delays, which was recently considered by Yang. By choosing the nonlinear interaction strength as a bifurcation parameter, we prove that Hopf bifurcation occurs. We determine the stability of the bifurcating periodic solutions and the direction of the Hopf bifurcation by applying the normal form theory and the center manifold theorem. Finally, we show a numerical example to verify the theoretical analysis

  7. Local stability and Hopf bifurcation in small-world delayed networks

    Energy Technology Data Exchange (ETDEWEB)

    Li Chunguang E-mail: cgli@uestc.edu.cn; Chen Guanrong E-mail: gchen@ee.cityu.edu.hk

    2004-04-01

    The notion of small-world networks, recently introduced by Watts and Strogatz, has attracted increasing interest in studying the interesting properties of complex networks. Notice that, a signal or influence travelling on a small-world network often is associated with time-delay features, which are very common in biological and physical networks. Also, the interactions within nodes in a small-world network are often nonlinear. In this paper, we consider a small-world networks model with nonlinear interactions and time delays, which was recently considered by Yang. By choosing the nonlinear interaction strength as a bifurcation parameter, we prove that Hopf bifurcation occurs. We determine the stability of the bifurcating periodic solutions and the direction of the Hopf bifurcation by applying the normal form theory and the center manifold theorem. Finally, we show a numerical example to verify the theoretical analysis.

  8. Immunizations on small worlds of tree-based wireless sensor networks

    DEFF Research Database (Denmark)

    Li, Qiao; Zhang, Bai-Hai; Cui, Ling-Guo

    2012-01-01

    , are conducted on small worlds of tree-based wireless sensor networks to combat the sensor viruses. With the former strategy, the infection extends exponentially, although the immunization effectively reduces the contagion speed. With the latter strategy, recurrent contagion oscillations occur in the small world......The sensor virus is a serious threat, as an attacker can simply send a single packet to compromise the entire sensor network. Epidemics become drastic with link additions among sensors when the small world phenomena occur. Two immunization strategies, uniform immunization and temporary immunization...

  9. Cascade theory in isotopic separation processes; Theorie des cascades en separation isotopique

    Energy Technology Data Exchange (ETDEWEB)

    Agostini, J P

    1994-06-01

    Three main areas are developed within the scope of this work: - the first one is devoted to fundamentals: separative power, value function, ideal cascade and square cascade. Applications to two main cases are carried out, namely: Study of binary isotopic mix, Study of processes with a small enrichment coefficient. - The second one is devoted to cascade coupling -high-flux coupling (more widely used and better known) as well as low-flux coupling are presented and compared to one another. - The third one is an outlook on problems linked to cascade transients. Those problem are somewhat intricate and their interest lies mainly into two areas: economics where the start-up time may have a large influence on the interests paid during the construction and start-up period, military productions where the start-up time has a direct bearing on the production schedule. (author). 50 figs. 3 annexes. 12 refs. 6 tabs.

  10. Dynamics in small worlds of tree topologies of wireless sensor networks

    DEFF Research Database (Denmark)

    Li, Qiao; Zhang, Baihai; Fan, Zhun

    2012-01-01

    Tree topologies, which construct spatial graphs with large characteristic path lengths and small clustering coefficients, are ubiquitous in deployments of wireless sensor networks. Small worlds are investigated in tree-based networks. Due to link additions, characteristic path lengths reduce...... rapidly and clustering coefficients increase greatly. A tree abstract, Cayley tree, is considered for the study of the navigation algorithm, which runs automatically in the small worlds of tree-based networks. In the further study, epidemics in the small worlds of tree-based wireless sensor networks...

  11. On structural identifiability analysis of the cascaded linear dynamic systems in isotopically non-stationary 13C labelling experiments.

    Science.gov (United States)

    Lin, Weilu; Wang, Zejian; Huang, Mingzhi; Zhuang, Yingping; Zhang, Siliang

    2018-06-01

    The isotopically non-stationary 13C labelling experiments, as an emerging experimental technique, can estimate the intracellular fluxes of the cell culture under an isotopic transient period. However, to the best of our knowledge, the issue of the structural identifiability analysis of non-stationary isotope experiments is not well addressed in the literature. In this work, the local structural identifiability analysis for non-stationary cumomer balance equations is conducted based on the Taylor series approach. The numerical rank of the Jacobian matrices of the finite extended time derivatives of the measured fractions with respect to the free parameters is taken as the criterion. It turns out that only one single time point is necessary to achieve the structural identifiability analysis of the cascaded linear dynamic system of non-stationary isotope experiments. The equivalence between the local structural identifiability of the cascaded linear dynamic systems and the local optimum condition of the nonlinear least squares problem is elucidated in the work. Optimal measurements sets can then be determined for the metabolic network. Two simulated metabolic networks are adopted to demonstrate the utility of the proposed method. Copyright © 2018 Elsevier Inc. All rights reserved.

  12. Walking and Talking Geography: A Small-World Approach

    Science.gov (United States)

    Fertig, Gary; Silverman, Rick

    2007-01-01

    When teaching geography to students in the primary grades, teachers should provide firsthand experiences that young children need to make meaningful sense of their world. David Sobel, author of "Mapmaking with Children: Sense of Place Education for the Elementary Years," suggests that teachers in the early grades adopt a small-world approach to…

  13. Hodge Decomposition of Information Flow on Small-World Networks.

    Science.gov (United States)

    Haruna, Taichi; Fujiki, Yuuya

    2016-01-01

    We investigate the influence of the small-world topology on the composition of information flow on networks. By appealing to the combinatorial Hodge theory, we decompose information flow generated by random threshold networks on the Watts-Strogatz model into three components: gradient, harmonic and curl flows. The harmonic and curl flows represent globally circular and locally circular components, respectively. The Watts-Strogatz model bridges the two extreme network topologies, a lattice network and a random network, by a single parameter that is the probability of random rewiring. The small-world topology is realized within a certain range between them. By numerical simulation we found that as networks become more random the ratio of harmonic flow to the total magnitude of information flow increases whereas the ratio of curl flow decreases. Furthermore, both quantities are significantly enhanced from the level when only network structure is considered for the network close to a random network and a lattice network, respectively. Finally, the sum of these two ratios takes its maximum value within the small-world region. These findings suggest that the dynamical information counterpart of global integration and that of local segregation are the harmonic flow and the curl flow, respectively, and that a part of the small-world region is dominated by internal circulation of information flow.

  14. Hodge decomposition of information flow on small-world networks

    Directory of Open Access Journals (Sweden)

    Taichi Haruna

    2016-09-01

    Full Text Available We investigate the influence of the small-world topology on the composition of information flow on networks. By appealing to the combinatorial Hodge theory, we decompose information flow generated by random threshold networks on the Watts-Strogatz model into three components: gradient, harmonic and curl flows. The harmonic and curl flows represent globally circular and locally circular components, respectively. The Watts-Strogatz model bridges the two extreme network topologies, a lattice network and a random network, by a single parameter that is the probability of random rewiring. The small-world topology is realized within a certain range between them. By numerical simulation we found that as networks become more random the ratio of harmonic flow to the total magnitude of information flow increases whereas the ratio of curl flow decreases. Furthermore, both quantities are significantly enhanced from the level when only network structure is considered for the network close to a random network and a lattice network, respectively. Finally, the sum of these two ratios takes its maximum value within the small-world region. These findings suggest that the dynamical information counterpart of global integration and that of local segregation are the harmonic flow and the curl flow, respectively, and that a part of the small-world region is dominated by internal circulation of information flow.

  15. Implementation of Cascade Gamma and Positron Range Corrections for I-124 Small Animal PET

    Science.gov (United States)

    Harzmann, S.; Braun, F.; Zakhnini, A.; Weber, W. A.; Pietrzyk, U.; Mix, M.

    2014-02-01

    Small animal Positron Emission Tomography (PET) should provide accurate quantification of regional radiotracer concentrations and high spatial resolution. This is challenging for non-pure positron emitters with high positron endpoint energies, such as I-124: On the one hand the cascade gammas emitted from this isotope can produce coincidence events with the 511 keV annihilation photons leading to quantification errors. On the other hand the long range of the high energy positron degrades spatial resolution. This paper presents the implementation of a comprehensive correction technique for both of these effects. The established corrections include a modified sinogram-based tail-fitting approach to correct for scatter, random and cascade gamma coincidences and a compensation for resolution degradation effects during the image reconstruction. Resolution losses were compensated for by an iterative algorithm which incorporates a convolution kernel derived from line source measurements for the microPET Focus 120 system. The entire processing chain for these corrections was implemented, whereas previous work has only addressed parts of this process. Monte Carlo simulations with GATE and measurements of mice with the microPET Focus 120 show that the proposed method reduces absolute quantification errors on average to 2.6% compared to 15.6% for the ordinary Maximum Likelihood Expectation Maximization algorithm. Furthermore resolution was improved in the order of 11-29% depending on the number of convolution iterations. In summary, a comprehensive, fast and robust algorithm for the correction of small animal PET studies with I-124 was developed which improves quantitative accuracy and spatial resolution.

  16. Small-world human brain networks: Perspectives and challenges.

    Science.gov (United States)

    Liao, Xuhong; Vasilakos, Athanasios V; He, Yong

    2017-06-01

    Modelling the human brain as a complex network has provided a powerful mathematical framework to characterize the structural and functional architectures of the brain. In the past decade, the combination of non-invasive neuroimaging techniques and graph theoretical approaches enable us to map human structural and functional connectivity patterns (i.e., connectome) at the macroscopic level. One of the most influential findings is that human brain networks exhibit prominent small-world organization. Such a network architecture in the human brain facilitates efficient information segregation and integration at low wiring and energy costs, which presumably results from natural selection under the pressure of a cost-efficiency balance. Moreover, the small-world organization undergoes continuous changes during normal development and ageing and exhibits dramatic alterations in neurological and psychiatric disorders. In this review, we survey recent advances regarding the small-world architecture in human brain networks and highlight the potential implications and applications in multidisciplinary fields, including cognitive neuroscience, medicine and engineering. Finally, we highlight several challenging issues and areas for future research in this rapidly growing field. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Learning optimal embedded cascades.

    Science.gov (United States)

    Saberian, Mohammad Javad; Vasconcelos, Nuno

    2012-10-01

    The problem of automatic and optimal design of embedded object detector cascades is considered. Two main challenges are identified: optimization of the cascade configuration and optimization of individual cascade stages, so as to achieve the best tradeoff between classification accuracy and speed, under a detection rate constraint. Two novel boosting algorithms are proposed to address these problems. The first, RCBoost, formulates boosting as a constrained optimization problem which is solved with a barrier penalty method. The constraint is the target detection rate, which is met at all iterations of the boosting process. This enables the design of embedded cascades of known configuration without extensive cross validation or heuristics. The second, ECBoost, searches over cascade configurations to achieve the optimal tradeoff between classification risk and speed. The two algorithms are combined into an overall boosting procedure, RCECBoost, which optimizes both the cascade configuration and its stages under a detection rate constraint, in a fully automated manner. Extensive experiments in face, car, pedestrian, and panda detection show that the resulting detectors achieve an accuracy versus speed tradeoff superior to those of previous methods.

  18. Robust emergence of small-world structure in networks of spiking neurons.

    Science.gov (United States)

    Kwok, Hoi Fei; Jurica, Peter; Raffone, Antonino; van Leeuwen, Cees

    2007-03-01

    Spontaneous activity in biological neural networks shows patterns of dynamic synchronization. We propose that these patterns support the formation of a small-world structure-network connectivity optimal for distributed information processing. We present numerical simulations with connected Hindmarsh-Rose neurons in which, starting from random connection distributions, small-world networks evolve as a result of applying an adaptive rewiring rule. The rule connects pairs of neurons that tend fire in synchrony, and disconnects ones that fail to synchronize. Repeated application of the rule leads to small-world structures. This mechanism is robustly observed for bursting and irregular firing regimes.

  19. Spatial prisoner's dilemma optimally played in small-world networks

    International Nuclear Information System (INIS)

    Masuda, Naoki; Aihara, Kazuyuki

    2003-01-01

    Cooperation is commonly found in ecological and social systems even when it apparently seems that individuals can benefit from selfish behavior. We investigate how cooperation emerges with the spatial prisoner's dilemma played in a class of networks ranging from regular lattices to random networks. We find that, among these networks, small-world topology is the optimal structure when we take into account the speed at which cooperative behavior propagates. Our results may explain why the small-world properties are self-organized in real networks

  20. A virtual component method in numerical computation of cascades for isotope separation

    International Nuclear Information System (INIS)

    Zeng Shi; Cheng Lu

    2014-01-01

    The analysis, optimization, design and operation of cascades for isotope separation involve computations of cascades. In analytical analysis of cascades, using virtual components is a very useful analysis method. For complicated cases of cascades, numerical analysis has to be employed. However, bound up to the conventional idea that the concentration of a virtual component should be vanishingly small, virtual component is not yet applied to numerical computations. Here a method of introducing the method of using virtual components to numerical computations is elucidated, and its application to a few types of cascades is explained and tested by means of numerical experiments. The results show that the concentration of a virtual component is not restrained at all by the 'vanishingly small' idea. For the same requirements on cascades, the cascades obtained do not depend on the concentrations of virtual components. (authors)

  1. Nitrogen Cascade: An Opportunity to Integrate Biogeochemistry and Policy

    Science.gov (United States)

    Galloway, J. N.; Moomaw, W. R.; Theis, T. L.

    2008-12-01

    It began with micro-organisms millions of years ago, was enhanced by the burning of fossil carbon in the last several hundred years, and was magnified by a patent filed one hundred years ago. Today, the combined actions of cultivation-induced biological nitrogen fixation, fossil fuel combustion and the Haber-Bosch process have exceeded natural terrestrial processes in converting N22 to nitrogen compounds that are biologically, chemically or physically reactive (reactive nitrogen, Nr). While the benefits of Nr are well understood, many of the adverse consequences of excessive Nr are invisible from a policy perspective. Over the past century, the fundamental knowledge on nitrogen processes has advanced to the point where we have a good understanding of nitrogen's biogeochemical cycle, the role of humans in altering the cycle, and the consequences of the alterations. This knowledge has collectively led us to two conclusions-the consequences of intensive human influence on the nitrogen cycle leads to a cascade of ecosystem and human effects which need to be managed. Secondly, the management is complicated by the facts that it not only has to be integrated, but it also has to take into account that the management should not lower the ability of managed ecosystems to produce food for the world's peoples. The framework of the nitrogen cascade provides us with a structure for better identifying intervention points, and more effective policies, technologies and measures to prevent or mitigate the adverse impacts of reactive nitrogen, while enhancing its beneficial uses. We can now begin to use our understanding of science to set priorities and craft new policy strategies. For many regions of the world, the science is strong enough to manage nitrogen and there are existing tools to do so. However, the tools are not integrated, critical tools are missing and most importantly, there are nitrogen-rich regions of the world where the science is lacking, and nitrogen-poor regions

  2. Cascading Dynamics of Heterogenous Scale-Free Networks with Recovery Mechanism

    Directory of Open Access Journals (Sweden)

    Shudong Li

    2013-01-01

    Full Text Available In network security, how to use efficient response methods against cascading failures of complex networks is very important. In this paper, concerned with the highest-load attack (HL and random attack (RA on one edge, we define five kinds of weighting strategies to assign the external resources for recovering the edges from cascading failures in heterogeneous scale-free (SF networks. The influence of external resources, the tolerance parameter, and the different weighting strategies on SF networks against cascading failures is investigated carefully. We find that, under HL attack, the fourth kind of weighting method can more effectively improve the integral robustness of SF networks, simultaneously control the spreading velocity, and control the outburst of cascading failures in SF networks than other methods. Moreover, the third method is optimal if we only knew the local structure of SF networks and the uniform assignment is the worst. The simulations of the real-world autonomous system in, Internet have also supported our findings. The results are useful for using efficient response strategy against the emergent accidents and controlling the cascading failures in the real-world networks.

  3. Cascade-based attacks on complex networks

    Science.gov (United States)

    Motter, Adilson E.; Lai, Ying-Cheng

    2002-12-01

    We live in a modern world supported by large, complex networks. Examples range from financial markets to communication and transportation systems. In many realistic situations the flow of physical quantities in the network, as characterized by the loads on nodes, is important. We show that for such networks where loads can redistribute among the nodes, intentional attacks can lead to a cascade of overload failures, which can in turn cause the entire or a substantial part of the network to collapse. This is relevant for real-world networks that possess a highly heterogeneous distribution of loads, such as the Internet and power grids. We demonstrate that the heterogeneity of these networks makes them particularly vulnerable to attacks in that a large-scale cascade may be triggered by disabling a single key node. This brings obvious concerns on the security of such systems.

  4. Network 'small-world-ness': a quantitative method for determining canonical network equivalence.

    Directory of Open Access Journals (Sweden)

    Mark D Humphries

    Full Text Available BACKGROUND: Many technological, biological, social, and information networks fall into the broad class of 'small-world' networks: they have tightly interconnected clusters of nodes, and a shortest mean path length that is similar to a matched random graph (same number of nodes and edges. This semi-quantitative definition leads to a categorical distinction ('small/not-small' rather than a quantitative, continuous grading of networks, and can lead to uncertainty about a network's small-world status. Moreover, systems described by small-world networks are often studied using an equivalent canonical network model--the Watts-Strogatz (WS model. However, the process of establishing an equivalent WS model is imprecise and there is a pressing need to discover ways in which this equivalence may be quantified. METHODOLOGY/PRINCIPAL FINDINGS: We defined a precise measure of 'small-world-ness' S based on the trade off between high local clustering and short path length. A network is now deemed a 'small-world' if S>1--an assertion which may be tested statistically. We then examined the behavior of S on a large data-set of real-world systems. We found that all these systems were linked by a linear relationship between their S values and the network size n. Moreover, we show a method for assigning a unique Watts-Strogatz (WS model to any real-world network, and show analytically that the WS models associated with our sample of networks also show linearity between S and n. Linearity between S and n is not, however, inevitable, and neither is S maximal for an arbitrary network of given size. Linearity may, however, be explained by a common limiting growth process. CONCLUSIONS/SIGNIFICANCE: We have shown how the notion of a small-world network may be quantified. Several key properties of the metric are described and the use of WS canonical models is placed on a more secure footing.

  5. Small hydro power project operating in cascade; Projeto de pequenas centrais hidreletricas operando em cascata

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Robson Siqueira Filadelfo dos [Minas Gerais Univ., Belo Horizonte (Brazil). Dept. de Engenharia Nuclear; Martinez, Carlos Barreira; Macedo, Alberto Amarante [Minas Gerais Univ., Belo Horizonte (Brazil). Dept. de Engenharia Hidraulica e Recursos Hidricos

    1999-07-01

    Small Hydro Power is a good option of generation mainly when they are located close to the consumers, because they demand smaller absolute value of invested capital and smaller time of maturation. Besides, the great repressed demand, mainly in the schedules of point, and the recovery of the values of the tariffs has been showed to private investor for this type of central. This paper develops a new method that allows to give agility to the study of small hydropower operating in cascade form in order to optimize the cost-benefit relationship of the enterprise. Approaches are presented for the evaluation of this type of system, the methodology of partition of falls and the proposed model. A case study, in which this method is applied, is shown at the end of this work. (author)

  6. Damage Spreading in Spatial and Small-world Random Boolean Networks

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Qiming [Fermilab; Teuscher, Christof [Portland State U.

    2014-02-18

    The study of the response of complex dynamical social, biological, or technological networks to external perturbations has numerous applications. Random Boolean Networks (RBNs) are commonly used a simple generic model for certain dynamics of complex systems. Traditionally, RBNs are interconnected randomly and without considering any spatial extension and arrangement of the links and nodes. However, most real-world networks are spatially extended and arranged with regular, power-law, small-world, or other non-random connections. Here we explore the RBN network topology between extreme local connections, random small-world, and pure random networks, and study the damage spreading with small perturbations. We find that spatially local connections change the scaling of the relevant component at very low connectivities ($\\bar{K} \\ll 1$) and that the critical connectivity of stability $K_s$ changes compared to random networks. At higher $\\bar{K}$, this scaling remains unchanged. We also show that the relevant component of spatially local networks scales with a power-law as the system size N increases, but with a different exponent for local and small-world networks. The scaling behaviors are obtained by finite-size scaling. We further investigate the wiring cost of the networks. From an engineering perspective, our new findings provide the key design trade-offs between damage spreading (robustness), the network's wiring cost, and the network's communication characteristics.

  7. Stability of the spreading in small-world network with predictive controller

    International Nuclear Information System (INIS)

    Bao, Z.J.; Jiang, Q.Y.; Yan, W.J.; Cao, Y.J.

    2010-01-01

    In this Letter, we apply the predictive control strategy to suppress the propagation of diseases or viruses in small-world network. The stability of small-world spreading model with predictive controller is investigated. The sufficient and necessary stability condition is given, which is closely related to the controller parameters and small-world rewiring probability p. Our simulations discover a phenomenon that, with the fixed predictive controller parameters, the spreading dynamics become more and more stable when p decreases from a larger value to a smaller one, and the suitable controller parameters can effectively suppress the spreading behaviors even when p varies within the whole spectrum, and the unsuitable controller parameters can lead to oscillation when p lies within a certain range.

  8. Scaling and percolation in the small-world network model

    Energy Technology Data Exchange (ETDEWEB)

    Newman, M. E. J. [Santa Fe Institute, 1399 Hyde Park Road, Santa Fe, New Mexico 87501 (United States); Watts, D. J. [Santa Fe Institute, 1399 Hyde Park Road, Santa Fe, New Mexico 87501 (United States)

    1999-12-01

    In this paper we study the small-world network model of Watts and Strogatz, which mimics some aspects of the structure of networks of social interactions. We argue that there is one nontrivial length-scale in the model, analogous to the correlation length in other systems, which is well-defined in the limit of infinite system size and which diverges continuously as the randomness in the network tends to zero, giving a normal critical point in this limit. This length-scale governs the crossover from large- to small-world behavior in the model, as well as the number of vertices in a neighborhood of given radius on the network. We derive the value of the single critical exponent controlling behavior in the critical region and the finite size scaling form for the average vertex-vertex distance on the network, and, using series expansion and Pade approximants, find an approximate analytic form for the scaling function. We calculate the effective dimension of small-world graphs and show that this dimension varies as a function of the length-scale on which it is measured, in a manner reminiscent of multifractals. We also study the problem of site percolation on small-world networks as a simple model of disease propagation, and derive an approximate expression for the percolation probability at which a giant component of connected vertices first forms (in epidemiological terms, the point at which an epidemic occurs). The typical cluster radius satisfies the expected finite size scaling form with a cluster size exponent close to that for a random graph. All our analytic results are confirmed by extensive numerical simulations of the model. (c) 1999 The American Physical Society.

  9. Scaling and percolation in the small-world network model

    International Nuclear Information System (INIS)

    Newman, M. E. J.; Watts, D. J.

    1999-01-01

    In this paper we study the small-world network model of Watts and Strogatz, which mimics some aspects of the structure of networks of social interactions. We argue that there is one nontrivial length-scale in the model, analogous to the correlation length in other systems, which is well-defined in the limit of infinite system size and which diverges continuously as the randomness in the network tends to zero, giving a normal critical point in this limit. This length-scale governs the crossover from large- to small-world behavior in the model, as well as the number of vertices in a neighborhood of given radius on the network. We derive the value of the single critical exponent controlling behavior in the critical region and the finite size scaling form for the average vertex-vertex distance on the network, and, using series expansion and Pade approximants, find an approximate analytic form for the scaling function. We calculate the effective dimension of small-world graphs and show that this dimension varies as a function of the length-scale on which it is measured, in a manner reminiscent of multifractals. We also study the problem of site percolation on small-world networks as a simple model of disease propagation, and derive an approximate expression for the percolation probability at which a giant component of connected vertices first forms (in epidemiological terms, the point at which an epidemic occurs). The typical cluster radius satisfies the expected finite size scaling form with a cluster size exponent close to that for a random graph. All our analytic results are confirmed by extensive numerical simulations of the model. (c) 1999 The American Physical Society

  10. Small-world network effects on innovation: evidences from nanotechnology patenting

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Yuan [University of Maryland, Robert H. Smith School of Business (United States); Guan, JianCheng, E-mail: guanjianch@ucas.ac.cn [University of Chinese Academy of Sciences, School of Economics and Management (China)

    2016-11-15

    This paper explores the effects of collaboration network on innovation in nanotechnology. We extend the idea of small-world to the heterogeneous network positions of actors by capturing the variation of how closely a given actor is connected to others in the same network and how clustered its neighbors are. We test the effects of small-world network in the context of nanotechnology patenting in China. Empirical results reveal that small-worldness, or the co-existence of high clustering and low path length in the network, displays inverse U-shape relationships with future patent output of the individual inventors and the system. Interestingly, the inflection point of the nonlinear relationship is significantly higher at the individual level. Based on these findings, we suggest that researchers of nanotechnology maintain a balance between friends in close-knit inner circles and colleagues in distant areas in their collaboration decisions and that policymakers interested in furthering the field offer collaboration opportunities for researchers in distant locations and areas.

  11. Small-world network effects on innovation: evidences from nanotechnology patenting

    International Nuclear Information System (INIS)

    Shi, Yuan; Guan, JianCheng

    2016-01-01

    This paper explores the effects of collaboration network on innovation in nanotechnology. We extend the idea of small-world to the heterogeneous network positions of actors by capturing the variation of how closely a given actor is connected to others in the same network and how clustered its neighbors are. We test the effects of small-world network in the context of nanotechnology patenting in China. Empirical results reveal that small-worldness, or the co-existence of high clustering and low path length in the network, displays inverse U-shape relationships with future patent output of the individual inventors and the system. Interestingly, the inflection point of the nonlinear relationship is significantly higher at the individual level. Based on these findings, we suggest that researchers of nanotechnology maintain a balance between friends in close-knit inner circles and colleagues in distant areas in their collaboration decisions and that policymakers interested in furthering the field offer collaboration opportunities for researchers in distant locations and areas.

  12. Small-world organization of self-similar modules in functional brain networks

    Science.gov (United States)

    Sigman, Mariano; Gallos, Lazaros; Makse, Hernan

    2012-02-01

    The modular organization of the brain implies the parallel nature of brain computations. These modules have to remain functionally independent, but at the same time they need to be sufficiently connected to guarantee the unitary nature of brain perception. Small-world architectures have been suggested as probable structures explaining this behavior. However, there is intrinsic tension between shortcuts generating small-worlds and the persistence of modularity. In this talk, we study correlations between the activity in different brain areas. We suggest that the functional brain network formed by the percolation of strong links is highly modular. Contrary to the common view, modules are self-similar and therefore are very far from being small-world. Incorporating the weak ties to the network converts it into a small-world preserving an underlying backbone of well-defined modules. Weak ties are shown to follow a pattern that maximizes information transfer with minimal wiring costs. This architecture is reminiscent of the concept of weak-ties strength in social networks and provides a natural solution to the puzzle of efficient infomration flow in the highly modular structure of the brain.

  13. Overload cascading failure on complex networks with heterogeneous load redistribution

    Science.gov (United States)

    Hou, Yueyi; Xing, Xiaoyun; Li, Menghui; Zeng, An; Wang, Yougui

    2017-09-01

    Many real systems including the Internet, power-grid and financial networks experience rare but large overload cascading failures triggered by small initial shocks. Many models on complex networks have been developed to investigate this phenomenon. Most of these models are based on the load redistribution process and assume that the load on a failed node shifts to nearby nodes in the networks either evenly or according to the load distribution rule before the cascade. Inspired by the fact that real power-grid tends to place the excess load on the nodes with high remaining capacities, we study a heterogeneous load redistribution mechanism in a simplified sandpile model in this paper. We find that weak heterogeneity in load redistribution can effectively mitigate the cascade while strong heterogeneity in load redistribution may even enlarge the size of the final failure. With a parameter θ to control the degree of the redistribution heterogeneity, we identify a rather robust optimal θ∗ = 1. Finally, we find that θ∗ tends to shift to a larger value if the initial sand distribution is homogeneous.

  14. Potts Model in One-Dimension on Directed Small-World Networks

    Science.gov (United States)

    Aquino, Édio O.; Lima, F. W. S.; Araújo, Ascânio D.; Costa Filho, Raimundo N.

    2018-06-01

    The critical properties of the Potts model with q=3 and 8 states in one-dimension on directed small-world networks are investigated. This disordered system is simulated by updating it with the Monte Carlo heat bath algorithm. The Potts model on these directed small-world networks presents in fact a second-order phase transition with a new set of critical exponents for q=3 considering a rewiring probability p=0.1. For q=8 the system exhibits only a first-order phase transition independent of p.

  15. Cascade theory in isotopic separation processes

    International Nuclear Information System (INIS)

    Agostini, J.P.

    1994-06-01

    Three main areas are developed within the scope of this work: - the first one is devoted to fundamentals: separative power, value function, ideal cascade and square cascade. Applications to two main cases are carried out, namely: Study of binary isotopic mix, Study of processes with a small enrichment coefficient. - The second one is devoted to cascade coupling -high-flux coupling (more widely used and better known) as well as low-flux coupling are presented and compared to one another. - The third one is an outlook on problems linked to cascade transients. Those problem are somewhat intricate and their interest lies mainly into two areas: economics where the start-up time may have a large influence on the interests paid during the construction and start-up period, military productions where the start-up time has a direct bearing on the production schedule. (author). 50 figs. 3 annexes. 12 refs. 6 tabs

  16. An effective method to improve the robustness of small-world networks under attack

    International Nuclear Information System (INIS)

    Zhang Zheng-Zhen; Xu Wen-Jun; Lin Jia-Ru; Zeng Shang-You

    2014-01-01

    In this study, the robustness of small-world networks to three types of attack is investigated. Global efficiency is introduced as the network coefficient to measure the robustness of a small-world network. The simulation results prove that an increase in rewiring probability or average degree can enhance the robustness of the small-world network under all three types of attack. The effectiveness of simultaneously increasing both rewiring probability and average degree is also studied, and the combined increase is found to significantly improve the robustness of the small-world network. Furthermore, the combined effect of rewiring probability and average degree on network robustness is shown to be several times greater than that of rewiring probability or average degree individually. This means that small-world networks with a relatively high rewiring probability and average degree have advantages both in network communications and in good robustness to attacks. Therefore, simultaneously increasing rewiring probability and average degree is an effective method of constructing realistic networks. Consequently, the proposed method is useful to construct efficient and robust networks in a realistic scenario. (interdisciplinary physics and related areas of science and technology)

  17. An Arabidopsis kinase cascade influences auxin-responsive cell expansion.

    Science.gov (United States)

    Enders, Tara A; Frick, Elizabeth M; Strader, Lucia C

    2017-10-01

    Mitogen-activated protein kinase (MPK) cascades are conserved mechanisms of signal transduction across eukaryotes. Despite the importance of MPK proteins in signaling events, specific roles for many Arabidopsis MPK proteins remain unknown. Multiple studies have suggested roles for MPK signaling in a variety of auxin-related processes. To identify MPK proteins with roles in auxin response, we screened mpk insertional alleles and identified mpk1-1 as a mutant that displays hypersensitivity in auxin-responsive cell expansion assays. Further, mutants defective in the upstream MAP kinase kinase MKK3 also display hypersensitivity in auxin-responsive cell expansion assays, suggesting that this MPK cascade affects auxin-influenced cell expansion. We found that MPK1 interacts with and phosphorylates ROP BINDING PROTEIN KINASE 1 (RBK1), a protein kinase that interacts with members of the Rho-like GTPases from Plants (ROP) small GTPase family. Similar to mpk1-1 and mkk3-1 mutants, rbk1 insertional mutants display auxin hypersensitivity, consistent with a possible role for RBK1 downstream of MPK1 in influencing auxin-responsive cell expansion. We found that RBK1 directly phosphorylates ROP4 and ROP6, supporting the possibility that RBK1 effects on auxin-responsive cell expansion are mediated through phosphorylation-dependent modulation of ROP activity. Our data suggest a MKK3 • MPK1 • RBK1 phosphorylation cascade that may provide a dynamic module for altering cell expansion. © 2017 The Authors The Plant Journal © 2017 John Wiley & Sons Ltd.

  18. Fastest learning in small-world neural networks

    International Nuclear Information System (INIS)

    Simard, D.; Nadeau, L.; Kroeger, H.

    2005-01-01

    We investigate supervised learning in neural networks. We consider a multi-layered feed-forward network with back propagation. We find that the network of small-world connectivity reduces the learning error and learning time when compared to the networks of regular or random connectivity. Our study has potential applications in the domain of data-mining, image processing, speech recognition, and pattern recognition

  19. Simulation of concentration spikes in cascades

    International Nuclear Information System (INIS)

    Wood, H.G.

    2006-01-01

    Research has been conducted to investigate the maximum possible enrichment that might be temporarily achieved in a facility that is producing enriched uranium for fuel for nuclear power reactors. The purpose is to provide information to evaluate if uranium enrichment facilities are producing 235 U enriched within declared limits appropriate for power reactors or if the facilities are actually producing more highly enriched uranium. The correlation between feed rate and separation factor in a gas centrifuge cascade shows that as flow decreases, the separation factor increases, thereby, creating small amounts of higher enriched uranium than would be found under optimum design operating conditions. The research uses a number of cascade enrichment programs to model the phenomenon and determine the maximum enrichment possible during the time transient of a gas centrifuge cascade. During cascade start-up, the flow through the centrifuges begins at lower than centrifuge design stage flow rates. Steady-state cascade models have been used to study the maximum 235 U concentrations that would be predicted in the cascade. These calculations should produce an upper bound of product concentrations expected during the transient phase of start-up. Due to the fact that there are different ways in which to start a cascade, several methods are used to determine the maximum enrichment during the time transient. Model cascades were created for gas centrifuges with several product to .feed assay separation factors. With this information, the models were defined and the equilibrium programs were used to determine the maximum enrichment level during the time transient. The calculations predict in a cascade with separation factor 1.254 designed to produce enriched uranium for the purpose of supplying reactor fuel, it would not be unreasonable to see some 235 U in the range of 12-15%. Higher assays produced during the start-up period might lead inspectors to believe the cascade is being

  20. Small Worlds in the Tree Topologies of Wireless Sensor Networks

    DEFF Research Database (Denmark)

    Qiao, Li; Lingguo, Cui; Baihai, Zhang

    2010-01-01

    In this study, the characteristics of small worlds are investigated in the context of the tree topologies of wireless sensor networks. Tree topologies, which construct spatial graphs with larger characteristic path lengths than random graphs and small clustering coefficients, are ubiquitous...... in wireless sensor networks. Suffering from the link rewiring or the link addition, the characteristic path length of the tree topology reduces rapidly and the clustering coefficient increases greatly. The variety of characteristic path length influences the time synchronization characteristics of wireless...... sensor networks greatly. With the increase of the link rewiring or the link addition probability, the time synchronization error decreases drastically. Two novel protocols named LEACH-SW and TREEPSI-SW are proposed to improve the performances of the sensor networks, in which the small world...

  1. Network marketing on a small-world network

    Science.gov (United States)

    Kim, Beom Jun; Jun, Tackseung; Kim, Jeong-Yoo; Choi, M. Y.

    2006-02-01

    We investigate a dynamic model of network marketing in a small-world network structure artificially constructed similarly to the Watts-Strogatz network model. Different from the traditional marketing, consumers can also play the role of the manufacturer's selling agents in network marketing, which is stimulated by the referral fee the manufacturer offers. As the wiring probability α is increased from zero to unity, the network changes from the one-dimensional regular directed network to the star network where all but one player are connected to one consumer. The price p of the product and the referral fee r are used as free parameters to maximize the profit of the manufacturer. It is observed that at α=0 the maximized profit is constant independent of the network size N while at α≠0, it increases linearly with N. This is in parallel to the small-world transition. It is also revealed that while the optimal value of p stays at an almost constant level in a broad range of α, that of r is sensitive to a change in the network structure. The consumer surplus is also studied and discussed.

  2. Large Scale Community Detection Using a Small World Model

    Directory of Open Access Journals (Sweden)

    Ranjan Kumar Behera

    2017-11-01

    Full Text Available In a social network, small or large communities within the network play a major role in deciding the functionalities of the network. Despite of diverse definitions, communities in the network may be defined as the group of nodes that are more densely connected as compared to nodes outside the group. Revealing such hidden communities is one of the challenging research problems. A real world social network follows small world phenomena, which indicates that any two social entities can be reachable in a small number of steps. In this paper, nodes are mapped into communities based on the random walk in the network. However, uncovering communities in large-scale networks is a challenging task due to its unprecedented growth in the size of social networks. A good number of community detection algorithms based on random walk exist in literature. In addition, when large-scale social networks are being considered, these algorithms are observed to take considerably longer time. In this work, with an objective to improve the efficiency of algorithms, parallel programming framework like Map-Reduce has been considered for uncovering the hidden communities in social network. The proposed approach has been compared with some standard existing community detection algorithms for both synthetic and real-world datasets in order to examine its performance, and it is observed that the proposed algorithm is more efficient than the existing ones.

  3. Two-dimensional small-world networks: Navigation with local information

    International Nuclear Information System (INIS)

    Chen Jianzhen; Liu Wei; Zhu Jianyang

    2006-01-01

    A navigation process is studied on a variant of the Watts-Strogatz small-world network model embedded on a square lattice. With probability p, each vertex sends out a long-range link, and the probability of the other end of this link falling on a vertex at lattice distance r away decays as r -α . Vertices on the network have knowledge of only their nearest neighbors. In a navigation process, messages are forwarded to a designated target. For α 1, a dynamic small world effect is observed, and the behavior of the scaling function at large enough pL is obtained. At α=2 and 3, this kind of scaling breaks down, and different functions of the average actual path length are obtained. For α>3, the average actual path length is nearly linear with network size

  4. Graph analysis of structural brain networks in Alzheimer's disease: beyond small world properties.

    Science.gov (United States)

    John, Majnu; Ikuta, Toshikazu; Ferbinteanu, Janina

    2017-03-01

    Changes in brain connectivity in patients with early Alzheimer's disease (AD) have been investigated using graph analysis. However, these studies were based on small data sets, explored a limited range of network parameters, and did not focus on more restricted sub-networks, where neurodegenerative processes may introduce more prominent alterations. In this study, we constructed structural brain networks out of 87 regions using data from 135 healthy elders and 100 early AD patients selected from the Open Access Series of Imaging Studies (OASIS) database. We evaluated the graph properties of these networks by investigating metrics of network efficiency, small world properties, segregation, product measures of complexity, and entropy. Because degenerative processes take place at different rates in different brain areas, analysis restricted to sub-networks may reveal changes otherwise undetected. Therefore, we first analyzed the graph properties of a network encompassing all brain areas considered together, and then repeated the analysis after dividing the brain areas into two sub-networks constructed by applying a clustering algorithm. At the level of large scale network, the analysis did not reveal differences between AD patients and controls. In contrast, the same analysis performed on the two sub-networks revealed that small worldness diminished with AD only in the sub-network containing the areas of medial temporal lobe known to be heaviest and earliest affected. The second sub-network, which did not present significant AD-induced modifications of 'classical' small world parameters, nonetheless showed a trend towards an increase in small world propensity, a novel metric that unbiasedly quantifies small world structure. Beyond small world properties, complexity and entropy measures indicated that the intricacy of connection patterns and structural diversity decreased in both sub-networks. These results show that neurodegenerative processes impact volumetric

  5. Robustness analysis of complex networks with power decentralization strategy via flow-sensitive centrality against cascading failures

    Science.gov (United States)

    Guo, Wenzhang; Wang, Hao; Wu, Zhengping

    2018-03-01

    Most existing cascading failure mitigation strategy of power grids based on complex network ignores the impact of electrical characteristics on dynamic performance. In this paper, the robustness of the power grid under a power decentralization strategy is analysed through cascading failure simulation based on AC flow theory. The flow-sensitive (FS) centrality is introduced by integrating topological features and electrical properties to help determine the siting of the generation nodes. The simulation results of the IEEE-bus systems show that the flow-sensitive centrality method is a more stable and accurate approach and can enhance the robustness of the network remarkably. Through the study of the optimal flow-sensitive centrality selection for different networks, we find that the robustness of the network with obvious small-world effect depends more on contribution of the generation nodes detected by community structure, otherwise, contribution of the generation nodes with important influence on power flow is more critical. In addition, community structure plays a significant role in balancing the power flow distribution and further slowing the propagation of failures. These results are useful in power grid planning and cascading failure prevention.

  6. Influence of choice of null network on small-world parameters of structural correlation networks.

    Directory of Open Access Journals (Sweden)

    S M Hadi Hosseini

    Full Text Available In recent years, coordinated variations in brain morphology (e.g., volume, thickness have been employed as a measure of structural association between brain regions to infer large-scale structural correlation networks. Recent evidence suggests that brain networks constructed in this manner are inherently more clustered than random networks of the same size and degree. Thus, null networks constructed by randomizing topology are not a good choice for benchmarking small-world parameters of these networks. In the present report, we investigated the influence of choice of null networks on small-world parameters of gray matter correlation networks in healthy individuals and survivors of acute lymphoblastic leukemia. Three types of null networks were studied: 1 networks constructed by topology randomization (TOP, 2 networks matched to the distributional properties of the observed covariance matrix (HQS, and 3 networks generated from correlation of randomized input data (COR. The results revealed that the choice of null network not only influences the estimated small-world parameters, it also influences the results of between-group differences in small-world parameters. In addition, at higher network densities, the choice of null network influences the direction of group differences in network measures. Our data suggest that the choice of null network is quite crucial for interpretation of group differences in small-world parameters of structural correlation networks. We argue that none of the available null models is perfect for estimation of small-world parameters for correlation networks and the relative strengths and weaknesses of the selected model should be carefully considered with respect to obtained network measures.

  7. Influence of Choice of Null Network on Small-World Parameters of Structural Correlation Networks

    Science.gov (United States)

    Hosseini, S. M. Hadi; Kesler, Shelli R.

    2013-01-01

    In recent years, coordinated variations in brain morphology (e.g., volume, thickness) have been employed as a measure of structural association between brain regions to infer large-scale structural correlation networks. Recent evidence suggests that brain networks constructed in this manner are inherently more clustered than random networks of the same size and degree. Thus, null networks constructed by randomizing topology are not a good choice for benchmarking small-world parameters of these networks. In the present report, we investigated the influence of choice of null networks on small-world parameters of gray matter correlation networks in healthy individuals and survivors of acute lymphoblastic leukemia. Three types of null networks were studied: 1) networks constructed by topology randomization (TOP), 2) networks matched to the distributional properties of the observed covariance matrix (HQS), and 3) networks generated from correlation of randomized input data (COR). The results revealed that the choice of null network not only influences the estimated small-world parameters, it also influences the results of between-group differences in small-world parameters. In addition, at higher network densities, the choice of null network influences the direction of group differences in network measures. Our data suggest that the choice of null network is quite crucial for interpretation of group differences in small-world parameters of structural correlation networks. We argue that none of the available null models is perfect for estimation of small-world parameters for correlation networks and the relative strengths and weaknesses of the selected model should be carefully considered with respect to obtained network measures. PMID:23840672

  8. Cascade fuzzy control for gas engine driven heat pump

    International Nuclear Information System (INIS)

    Li Shuze; Zhang Wugao; Zhang Rongrong; Lv Dexu; Huang Zhen

    2005-01-01

    In addition to absorption chillers, today's gas cooling technology includes gas engine driven heat pump systems (GEHP) in a range of capacities and temperature capacities suitable for most commercial air conditioning and refrigeration applications. Much is expected from GEHPs as a product that would help satisfy the air conditioning system demand from medium and small sized buildings, restrict electric power demand peaks in summer and save energy in general. This article describes a kind of control strategy for a GEHP, a cascade fuzzy control. GEHPs have large and varying time constants and their dynamic modeling cannot be easily achieved. A cascade control strategy is effective for systems that have large time constants and disturbances, and a fuzzy control strategy is fit for a system that lacks an accurate model. This cascade fuzzy control structure brings together the best merits of fuzzy control and cascade control structures. The performance of the cascade fuzzy control is compared to that of a cascade PI (proportional and integral) control strategy, and it is shown by example that the cascade fuzzy control strategy gives a better performance, reduced reaction time and smaller overshoot temperature

  9. Broad-scale small-world network topology induces optimal synchronization of flexible oscillators

    International Nuclear Information System (INIS)

    Markovič, Rene; Gosak, Marko; Marhl, Marko

    2014-01-01

    The discovery of small-world and scale-free properties of many man-made and natural complex networks has attracted increasing attention. Of particular interest is how the structural properties of a network facilitate and constrain its dynamical behavior. In this paper we study the synchronization of weakly coupled limit-cycle oscillators in dependence on the network topology as well as the dynamical features of individual oscillators. We show that flexible oscillators, characterized by near zero values of divergence, express maximal correlation in broad-scale small-world networks, whereas the non-flexible (rigid) oscillators are best correlated in more heterogeneous scale-free networks. We found that the synchronization behavior is governed by the interplay between the networks global efficiency and the mutual frequency adaptation. The latter differs for flexible and rigid oscillators. The results are discussed in terms of evolutionary advantages of broad-scale small-world networks in biological systems

  10. On the structural properties of small-world networks with range-limited shortcut links

    Science.gov (United States)

    Jia, Tao; Kulkarni, Rahul V.

    2013-12-01

    We explore a new variant of Small-World Networks (SWNs), in which an additional parameter (r) sets the length scale over which shortcuts are uniformly distributed. When r=0 we have an ordered network, whereas r=1 corresponds to the original Watts-Strogatz SWN model. These limited range SWNs have a similar degree distribution and scaling properties as the original SWN model. We observe the small-world phenomenon for r≪1, indicating that global shortcuts are not necessary for the small-world effect. For limited range SWNs, the average path length changes nonmonotonically with system size, whereas for the original SWN model it increases monotonically. We propose an expression for the average path length for limited range SWNs based on numerical simulations and analytical approximations.

  11. Small-world networks of fuzzy chaotic oscillators

    CERN Document Server

    Bucolo, M; Fortuna, L

    2003-01-01

    Small-world topology has been used to build lattices of nonlinear fuzzy systems. Chaotic units, ruled by linguistic description and with specified Lyapunov exponent, have been realized and connected using linear diffusion coefficient. The dynamic features of the networks versus the number of systems connected have been investigated to underline phenomena like spatiotemporal chaos and complete regularization. The synchronization characteristics in case of sparse long-term connections and the performances comparison with regular and random network configurations are shown.

  12. a Model Study of Small-Scale World Map Generalization

    Science.gov (United States)

    Cheng, Y.; Yin, Y.; Li, C. M.; Wu, W.; Guo, P. P.; Ma, X. L.; Hu, F. M.

    2018-04-01

    With the globalization and rapid development every filed is taking an increasing interest in physical geography and human economics. There is a surging demand for small scale world map in large formats all over the world. Further study of automated mapping technology, especially the realization of small scale production on a large scale global map, is the key of the cartographic field need to solve. In light of this, this paper adopts the improved model (with the map and data separated) in the field of the mapmaking generalization, which can separate geographic data from mapping data from maps, mainly including cross-platform symbols and automatic map-making knowledge engine. With respect to the cross-platform symbol library, the symbol and the physical symbol in the geographic information are configured at all scale levels. With respect to automatic map-making knowledge engine consists 97 types, 1086 subtypes, 21845 basic algorithm and over 2500 relevant functional modules.In order to evaluate the accuracy and visual effect of our model towards topographic maps and thematic maps, we take the world map generalization in small scale as an example. After mapping generalization process, combining and simplifying the scattered islands make the map more explicit at 1 : 2.1 billion scale, and the map features more complete and accurate. Not only it enhance the map generalization of various scales significantly, but achieve the integration among map-makings of various scales, suggesting that this model provide a reference in cartographic generalization for various scales.

  13. A small-world network model of facial emotion recognition.

    Science.gov (United States)

    Takehara, Takuma; Ochiai, Fumio; Suzuki, Naoto

    2016-01-01

    Various models have been proposed to increase understanding of the cognitive basis of facial emotions. Despite those efforts, interactions between facial emotions have received minimal attention. If collective behaviours relating to each facial emotion in the comprehensive cognitive system could be assumed, specific facial emotion relationship patterns might emerge. In this study, we demonstrate that the frameworks of complex networks can effectively capture those patterns. We generate 81 facial emotion images (6 prototypes and 75 morphs) and then ask participants to rate degrees of similarity in 3240 facial emotion pairs in a paired comparison task. A facial emotion network constructed on the basis of similarity clearly forms a small-world network, which features an extremely short average network distance and close connectivity. Further, even if two facial emotions have opposing valences, they are connected within only two steps. In addition, we show that intermediary morphs are crucial for maintaining full network integration, whereas prototypes are not at all important. These results suggest the existence of collective behaviours in the cognitive systems of facial emotions and also describe why people can efficiently recognize facial emotions in terms of information transmission and propagation. For comparison, we construct three simulated networks--one based on the categorical model, one based on the dimensional model, and one random network. The results reveal that small-world connectivity in facial emotion networks is apparently different from those networks, suggesting that a small-world network is the most suitable model for capturing the cognitive basis of facial emotions.

  14. Driving and driven architectures of directed small-world human brain functional networks.

    Directory of Open Access Journals (Sweden)

    Chaogan Yan

    Full Text Available Recently, increasing attention has been focused on the investigation of the human brain connectome that describes the patterns of structural and functional connectivity networks of the human brain. Many studies of the human connectome have demonstrated that the brain network follows a small-world topology with an intrinsically cohesive modular structure and includes several network hubs in the medial parietal regions. However, most of these studies have only focused on undirected connections between regions in which the directions of information flow are not taken into account. How the brain regions causally influence each other and how the directed network of human brain is topologically organized remain largely unknown. Here, we applied linear multivariate Granger causality analysis (GCA and graph theoretical approaches to a resting-state functional MRI dataset with a large cohort of young healthy participants (n = 86 to explore connectivity patterns of the population-based whole-brain functional directed network. This directed brain network exhibited prominent small-world properties, which obviously improved previous results of functional MRI studies showing weak small-world properties in the directed brain networks in terms of a kernel-based GCA and individual analysis. This brain network also showed significant modular structures associated with 5 well known subsystems: fronto-parietal, visual, paralimbic/limbic, subcortical and primary systems. Importantly, we identified several driving hubs predominantly located in the components of the attentional network (e.g., the inferior frontal gyrus, supplementary motor area, insula and fusiform gyrus and several driven hubs predominantly located in the components of the default mode network (e.g., the precuneus, posterior cingulate gyrus, medial prefrontal cortex and inferior parietal lobule. Further split-half analyses indicated that our results were highly reproducible between two

  15. Six Degrees of Information Seeking: Stanley Milgram and the Small World of the Library

    Science.gov (United States)

    James, Kathryn

    2006-01-01

    Stanley Milgram's 1967 "small world" social connectivity study is used to analyze information connectivity, or patron information-seeking behavior. The "small world" study, upon examination, offers a clear example of the failure of social connectivity. This failure is used to highlight the importance of the subjectivities of patron experience of…

  16. Network features and pathway analyses of a signal transduction cascade

    Directory of Open Access Journals (Sweden)

    Ryoji Yanashima

    2009-05-01

    Full Text Available The scale-free and small-world network models reflect the functional units of networks. However, when we investigated the network properties of a signaling pathway using these models, no significant differences were found between the original undirected graphs and the graphs in which inactive proteins were eliminated from the gene expression data. We analyzed signaling networks by focusing on those pathways that best reflected cellular function. Therefore, our analysis of pathways started from the ligands and progressed to transcription factors and cytoskeletal proteins. We employed the Python module to assess the target network. This involved comparing the original and restricted signaling cascades as a directed graph using microarray gene expression profiles of late onset Alzheimer's disease. The most commonly used method of shortest-path analysis neglects to consider the influences of alternative pathways that can affect the activation of transcription factors or cytoskeletal proteins. We therefore introduced included k-shortest paths and k-cycles in our network analysis using the Python modules, which allowed us to attain a reasonable computational time and identify k-shortest paths. This technique reflected results found in vivo and identified pathways not found when shortest path or degree analysis was applied. Our module enabled us to comprehensively analyse the characteristics of biomolecular networks and also enabled analysis of the effects of diseases considering the feedback loop and feedforward loop control structures as an alternative path.

  17. Small World Properties Generated by a New Algorithm Under Same Degree of All Nodes

    International Nuclear Information System (INIS)

    Li Yong; Fang Jinqing; Liu Qiang; Liang Yong

    2006-01-01

    Based on the model of the same degree of all nodes we proposed before, a new algorithm, the so-called 'spread all over vertices' (SAV) algorithm, is proposed for generating small-world properties from a regular ring lattices. During randomly rewiring connections the SAV is used to keep the unchanged number of links. Comparing the SAV algorithm with the Watts-Strogatz model and the 'spread all over boundaries' algorithm, three methods can have the same topological properties of the small world networks. These results offer diverse formation of small world networks. It is helpful to the research of some applications for dynamics of mutual oscillator inside nodes and interacting automata associated with networks.

  18. A Small State Maneuvering in the Changing World Order

    DEFF Research Database (Denmark)

    Sørensen, Camilla T. N.

    2016-01-01

    , especially the Danish approach to the BRICs, has developed in recent years, I show how Denmark – a small state – is trying to maneuver in the changing world order through a “creative agency” approach characterized by pragmatic low-profile activism. I develop a neoclassical realist framework and use...

  19. Major disruptions, inverse cascades, and the Strauss equations

    International Nuclear Information System (INIS)

    Montgomery, D.

    1982-01-01

    Current-carrying plasmas in a strong dc magnetic field are subject to violent disruptions above certain thresholds. At present difficult to verify, explanations are typically sought in terms of tearing modes. An alternative explanation is in terms of inverse magnetic helicity cascades, generated from a variety of possible sources of small-scale MHD turbulence. Strongly anisotropic MHD plasmas may be described by the Strauss equations. Indications of turbulent inverse cascade behavior for the Strauss equations are sought, in parallel with earlier examples from MHD and fluid mechanics

  20. Complete and phase synchronization in a heterogeneous small-world neuronal network

    International Nuclear Information System (INIS)

    Fang, Han; Qi-Shao, Lu; Quan-Bao, Ji; Marian, Wiercigroch

    2009-01-01

    Synchronous firing of neurons is thought to be important for information communication in neuronal networks. This paper investigates the complete and phase synchronization in a heterogeneous small-world chaotic Hindmarsh–Rose neuronal network. The effects of various network parameters on synchronization behaviour are discussed with some biological explanations. Complete synchronization of small-world neuronal networks is studied theoretically by the master stability function method. It is shown that the coupling strength necessary for complete or phase synchronization decreases with the neuron number, the node degree and the connection density are increased. The effect of heterogeneity of neuronal networks is also considered and it is found that the network heterogeneity has an adverse effect on synchrony. (general)

  1. Defect production in simulated cascades: Cascade quenching and short-term annealing

    International Nuclear Information System (INIS)

    Heinisch, H.L.

    1983-01-01

    Defect production in displacement cascades in copper has been modeled using the MARLOWE code to generate cascades and the stochastic annealing code ALSOME to simulate cascade quenching and short-term annealing of isolated cascades. Quenching is accomplished by using exaggerated values for defect mobilities and for critical reaction distances in ALSOME for a very short time. The quenched cascades are then short-term annealed with normal parameter values. The quenching parameter values were empirically determined by comparison with results of resistivity measurements. Throughout the collisional, quenching and short-term annealing phases of cascade development, the high energy cascades continue to behave as a collection of independent lower energy lobes. For recoils above about 30 keV the total number of defects and the numbers of free defects scale with the damage energy. As the energy decreases from 30 keV, defect production varies with the changing nature of the cascade configuration, resulting in more defects per unit damage energy. The simulated annealing of a low fluence of interacting cascades revealed an interstitial shielding effect on depleted zones during Stage I recovery. (orig.)

  2. A non-conventional isotope separation cascade without any mixing: net cascade

    International Nuclear Information System (INIS)

    Zeng Shi; Jiang Dongjun; Ying Zhengen

    2012-01-01

    A component has different concentrations in the incoming flows at a confluent point in all existing isotope separations cascades for multi-component isotope separation and mixing is inevitable, which results in deterioration of separation performance of the separation cascade. However, realization of no-mixing at a confluent point is impossible with a conventional cascade. A non-conventional isotope separation cascade, net cascade, is found to be able to realize no mixings for all components at confluent points, and its concept is further developed here. No-mixing is fulfilled by requiring symmetrical separation of two specified key components at every stage, and the procedure of realizing no-mixing is presented in detail. Some properties of net cascade are investigated preliminarily, and the results demonstrated the no-mixing property is indeed realized. Net cascade is the only separation cascade that so far possesses the no-mixing property. (authors)

  3. Storage capacity and retrieval time of small-world neural networks

    International Nuclear Information System (INIS)

    Oshima, Hiraku; Odagaki, Takashi

    2007-01-01

    To understand the influence of structure on the function of neural networks, we study the storage capacity and the retrieval time of Hopfield-type neural networks for four network structures: regular, small world, random networks generated by the Watts-Strogatz (WS) model, and the same network as the neural network of the nematode Caenorhabditis elegans. Using computer simulations, we find that (1) as the randomness of network is increased, its storage capacity is enhanced; (2) the retrieval time of WS networks does not depend on the network structure, but the retrieval time of C. elegans's neural network is longer than that of WS networks; (3) the storage capacity of the C. elegans network is smaller than that of networks generated by the WS model, though the neural network of C. elegans is considered to be a small-world network

  4. Simulated annealing of displacement cascades in FCC metals. 1. Beeler cascades

    International Nuclear Information System (INIS)

    Doran, D.G.; Burnett, R.A.

    1974-09-01

    An important source of damage to structural materials in fast reactors is the displacement of atoms from normal lattice sites. A high energy neutron may impart sufficient energy to an atom to initiate a displacement cascade consisting of a localized high density of hundreds of interstitials and vacancies. These defects subsequently interact to form clusters and to reduce their density by mutual annihilation. This short term annealing of an isolated cascade has been simulated at high and low temperatures using a correlated random walk model. The cascade representations used were developed by Beeler and the point defect properties were based on the model of γ-iron by Johnson. Low temperature anneals, characterized by no vacancy migration and a 104 site annihilation region (AR), resulted in 49 defect pairs at 20 keV and 11 pairs at 5 keV. High temperature anneals, characterized by both interstitial and vacancy migration and a 32 site AR, resulted in 68 pairs at 20 keV and 18 pairs at 5 keV when no cluster dissociation was permitted; most of the vacancies were in immobile clusters. These high temperature values dropped to 40 and 14 upon dissolution of the vacancy clusters. Parameter studies showed that, at a given temperature, the large AR resulted in about one-half as many defects as the small AR. Cluster size distributions and examples of spatial configurations are included. (U.S.)

  5. CasCADe: A Novel 4D Visualization System for Virtual Construction Planning.

    Science.gov (United States)

    Ivson, Paulo; Nascimento, Daniel; Celes, Waldemar; Barbosa, Simone Dj

    2018-01-01

    Building Information Modeling (BIM) provides an integrated 3D environment to manage large-scale engineering projects. The Architecture, Engineering and Construction (AEC) industry explores 4D visualizations over these datasets for virtual construction planning. However, existing solutions lack adequate visual mechanisms to inspect the underlying schedule and make inconsistencies readily apparent. The goal of this paper is to apply best practices of information visualization to improve 4D analysis of construction plans. We first present a review of previous work that identifies common use cases and limitations. We then consulted with AEC professionals to specify the main design requirements for such applications. These guided the development of CasCADe, a novel 4D visualization system where task sequencing and spatio-temporal simultaneity are immediately apparent. This unique framework enables the combination of diverse analytical features to create an information-rich analysis environment. We also describe how engineering collaborators used CasCADe to review the real-world construction plans of an Oil & Gas process plant. The system made evident schedule uncertainties, identified work-space conflicts and helped analyze other constructability issues. The results and contributions of this paper suggest new avenues for future research in information visualization for the AEC industry.

  6. LCA-based optimization of wood utilization under special consideration of a cascading use of wood.

    Science.gov (United States)

    Höglmeier, Karin; Steubing, Bernhard; Weber-Blaschke, Gabriele; Richter, Klaus

    2015-04-01

    Cascading, the use of the same unit of a resource in multiple successional applications, is considered as a viable means to improve the efficiency of resource utilization and to decrease environmental impacts. Wood, as a regrowing but nevertheless limited and increasingly in demand resource, can be used in cascades, thereby increasing the potential efficiency per unit of wood. This study aims to assess the influence of cascading wood utilization on optimizing the overall environmental impact of wood utilization. By combining a material flow model of existing wood applications - both for materials provision and energy production - with an algebraic optimization tool, the effects of the use of wood in cascades can be modelled and quantified based on life cycle impact assessment results for all production processes. To identify the most efficient wood allocation, the effects of a potential substitution of non-wood products were taken into account in a part of the model runs. The considered environmental indicators were global warming potential, particulate matter formation, land occupation and an aggregated single score indicator. We found that optimizing either the overall global warming potential or the value of the single score indicator of the system leads to a simultaneous relative decrease of all other considered environmental impacts. The relative differences between the impacts of the model run with and without the possibility of a cascading use of wood were 7% for global warming potential and the single score indicator, despite cascading only influencing a small part of the overall system, namely wood panel production. Cascading led to savings of up to 14% of the annual primary wood supply of the study area. We conclude that cascading can improve the overall performance of a wood utilization system. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Effect of the small-world structure on encoding performance in the primary visual cortex: an electrophysiological and modeling analysis.

    Science.gov (United States)

    Shi, Li; Niu, Xiaoke; Wan, Hong

    2015-05-01

    The biological networks have been widely reported to present small-world properties. However, the effects of small-world network structure on population's encoding performance remain poorly understood. To address this issue, we applied a small world-based framework to quantify and analyze the response dynamics of cell assemblies recorded from rat primary visual cortex, and further established a population encoding model based on small world-based generalized linear model (SW-GLM). The electrophysiological experimental results show that the small world-based population responses to different topological shapes present significant variation (t test, p 0.8), while no significant variation was found for control networks without considering their spatial connectivity (t test, p > 0.05; effect size: Hedge's g < 0.5). Furthermore, the numerical experimental results show that the predicted response under SW-GLM is more accurate and reliable compared to the control model without small-world structure, and the decoding performance is also improved about 10 % by taking the small-world structure into account. The above results suggest the important role of the small-world neural structure in encoding visual information for the neural population by providing electrophysiological and theoretical evidence, respectively. The study helps greatly to well understand the population encoding mechanisms of visual cortex.

  8. Critical behavior of the contact process on small-world networks

    Science.gov (United States)

    Ferreira, Ronan S.; Ferreira, Silvio C.

    2013-11-01

    We investigate the role of clustering on the critical behavior of the contact process (CP) on small-world networks using the Watts-Strogatz (WS) network model with an edge rewiring probability p. The critical point is well predicted by a homogeneous cluster-approximation for the limit of vanishing clustering ( p → 1). The critical exponents and dimensionless moment ratios of the CP are in agreement with those predicted by the mean-field theory for any p > 0. This independence on the network clustering shows that the small-world property is a sufficient condition for the mean-field theory to correctly predict the universality of the model. Moreover, we compare the CP dynamics on WS networks with rewiring probability p = 1 and random regular networks and show that the weak heterogeneity of the WS network slightly changes the critical point but does not alter other critical quantities of the model.

  9. Spiral Wave in Small-World Networks of Hodgkin-Huxley Neurons

    International Nuclear Information System (INIS)

    Ma Jun; Zhang Cairong; Yang Lijian; Wu Ying

    2010-01-01

    The effect of small-world connection and noise on the formation and transition of spiral wave in the networks of Hodgkin-Huxley neurons are investigated in detail. Some interesting results are found in our numerical studies. i) The quiescent neurons are activated to propagate electric signal to others by generating and developing spiral wave from spiral seed in small area. ii) A statistical factor is defined to describe the collective properties and phase transition induced by the topology of networks and noise. iii) Stable rotating spiral wave can be generated and keeps robust when the rewiring probability is below certain threshold, otherwise, spiral wave can not be developed from the spiral seed and spiral wave breakup occurs for a stable rotating spiral wave. iv) Gaussian white noise is introduced on the membrane of neurons to study the noise-induced phase transition on spiral wave in small-world networks of neurons. It is confirmed that Gaussian white noise plays active role in supporting and developing spiral wave in the networks of neurons, and appearance of smaller factor of synchronization indicates high possibility to induce spiral wave. (interdisciplinary physics and related areas of science and technology)

  10. Phase Transitions of an Epidemic Spreading Model in Small-World Networks

    Science.gov (United States)

    Hua, Da-Yin; Gao, Ke

    2011-06-01

    We propose a modified susceptible-infected-refractory-susceptible (SIRS) model to investigate the global oscillations of the epidemic spreading in Watts—Strogatz (WS) small-world networks. It is found that when an individual immunity does not change or decays slowly in an immune period, the system can exhibit complex transition from an infecting stationary state to a large amplitude sustained oscillation or an absorbing state with no infection. When the immunity decays rapidly in the immune period, the transition to the global oscillation disappears and there is no oscillation. Furthermore, based on the spatio-temporal evolution patterns and the phase diagram, it is disclosed that a long immunity period takes an important role in the emergence of the global oscillation in small-world networks.

  11. Lumley's energy cascade dissipation rate model for boundary-free turbulent shear flows

    Science.gov (United States)

    Duncan, B. S.

    1992-01-01

    True dissipation occurs mainly at the highest wavenumbers where the eddy sizes are comparatively small. These high wavenumbers receive their energy through the spectral cascade of energy starting with the largest eddies spilling energy into the smaller eddies, passing through each wavenumber until it is dissipated at the microscopic scale. However, a small percentage of the energy does not spill continuously through the cascade but is instantly passed to the higher wavenumbers. Consequently, the smallest eddies receive a certain amount of energy almost immediately. As the spectral energy cascade continues, the highest wavenumber needs a certain time to receive all the energy which has been transferred from the largest eddies. As such, there is a time delay, of the order of tau, between the generation of energy by the largest eddies and the eventual dissipation of this energy. For equilibrium turbulence at high Reynolds numbers, there is a wide range where energy is neither produced by the large eddies nor dissipated by viscosity, but is conserved and passed from wavenumber to higher wavenumbers. The rate at which energy cascades from one wavenumber to another is proportional to the energy contained within that wavenumber. This rate is constant and has been used in the past as a dissipation rate of turbulent kinetic energy. However, this is true only in steady, equilibrium turbulence. Most dissipation models contend that the production of dissipation is proportional to the production of energy and that the destruction of dissipation is proportional to the destruction of energy. In essence, these models state that the change in the dissipation rate is proportional to the change in the kinetic energy. This assumption is obviously incorrect for the case where there is no production of turbulent energy, yet energy continues to cascade from large to small eddies. If the time lag between the onset on the energy cascade to the destruction of energy at the microscale can be

  12. Extraction of network topology from multi-electrode recordings: Is there a small-world effect?

    Directory of Open Access Journals (Sweden)

    Felipe eGerhard

    2011-02-01

    Full Text Available The simultaneous recording of the activity of many neurons poses challenges for multivariate data analysis. Here, we propose a general scheme of reconstruction of the functional network from spike train recordings. Effective, causal interactions are estimated by fitting Generalized Linear Models (GLMs on the neural responses, incorporating effects of the neurons' self-history, of input from other neurons in the recorded network and of modulation by an external stimulus. The coupling terms arising from synaptic input can be transformed by thresholding into a binary connectivity matrix which is directed. Each link between two neurons represents a causal influence from one neuron to the other, given the observation of all other neurons from the population. The resulting graph is analyzed with respect to small-world and scale-free properties using quantitative measures for directed networks. Such graph-theoretic analyses have been performed on many complex dynamic networks, including the connectivity structure between different brain areas. Only few studies have attempted to look at the structure of cortical neural networks on the level of individual neurons. Here, using multi-electrode recordings from the visual system of the awake monkey, we find that cortical networks lack scale-free behavior, but show a small, but significant small-world structure. Assuming a simple distance-dependent probabilistic wiring between neurons, we find that this connectivity structure can account for all of the networks' observed small-world-ness. Moreover, for multi-electrode recordings the sampling of neurons is not uniform across the population. We show that the small-world-ness obtained by such a localized sub-sampling overestimates the strength of the true small-world-structure of the network. This bias is likely to be present in all previous experiments based on multi-electrode recordings.

  13. A Discrete Dynamical System Approach to Pathway Activation Profiles of Signaling Cascades.

    Science.gov (United States)

    Catozzi, S; Sepulchre, J-A

    2017-08-01

    In living organisms, cascades of covalent modification cycles are one of the major intracellular signaling mechanisms, allowing to transduce physical or chemical stimuli of the external world into variations of activated biochemical species within the cell. In this paper, we develop a novel method to study the stimulus-response of signaling cascades and overall the concept of pathway activation profile which is, for a given stimulus, the sequence of activated proteins at each tier of the cascade. Our approach is based on a correspondence that we establish between the stationary states of a cascade and pieces of orbits of a 2D discrete dynamical system. The study of its possible phase portraits in function of the biochemical parameters, and in particular of the contraction/expansion properties around the fixed points of this discrete map, as well as their bifurcations, yields a classification of the cascade tiers into three main types, whose biological impact within a signaling network is examined. In particular, our approach enables to discuss quantitatively the notion of cascade amplification/attenuation from this new perspective. The method allows also to study the interplay between forward and "retroactive" signaling, i.e., the upstream influence of an inhibiting drug bound to the last tier of the cascade.

  14. Complex Behavior in a Selective Aging Neuron Model Based on Small World Networks

    International Nuclear Information System (INIS)

    Zhang Guiqing; Chen Tianlun

    2008-01-01

    Complex behavior in a selective aging simple neuron model based on small world networks is investigated. The basic elements of the model are endowed with the main features of a neuron function. The structure of the selective aging neuron model is discussed. We also give some properties of the new network and find that the neuron model displays a power-law behavior. If the brain network is small world-like network, the mean avalanche size is almost the same unless the aging parameter is big enough.

  15. Stretched exponential dynamics of coupled logistic maps on a small-world network

    Science.gov (United States)

    Mahajan, Ashwini V.; Gade, Prashant M.

    2018-02-01

    We investigate the dynamic phase transition from partially or fully arrested state to spatiotemporal chaos in coupled logistic maps on a small-world network. Persistence of local variables in a coarse grained sense acts as an excellent order parameter to study this transition. We investigate the phase diagram by varying coupling strength and small-world rewiring probability p of nonlocal connections. The persistent region is a compact region bounded by two critical lines where band-merging crisis occurs. On one critical line, the persistent sites shows a nonexponential (stretched exponential) decay for all p while for another one, it shows crossover from nonexponential to exponential behavior as p → 1 . With an effectively antiferromagnetic coupling, coupling to two neighbors on either side leads to exchange frustration. Apart from exchange frustration, non-bipartite topology and nonlocal couplings in a small-world network could be a reason for anomalous relaxation. The distribution of trap times in asymptotic regime has a long tail as well. The dependence of temporal evolution of persistence on initial conditions is studied and a scaling form for persistence after waiting time is proposed. We present a simple possible model for this behavior.

  16. Investigation of cascade effect failure for tungsten armour

    International Nuclear Information System (INIS)

    Makhankov, A.; Barabash, V.; Berkhov, N.; Divavin, V.; Giniatullin, R.; Grigoriev, S.; Ibbott, C.; Komarov, V.; Labusov, A.; Mazul, I.; McDonald, J.; Tanchuk, V.; Youchison, D.

    2001-01-01

    The glancing angle of incident power on the target of a tokamak divertor results in doubled and highly peaked heat flux onto adjacent downstream tile in the case of lost of tile event (LOTE). As a result downstream tile has higher probability to fail resulting in triple loads to the next downstream tile and so on (cascade effect). This paper devoted to analytical and experimental investigation of the cascade effect failure for the flat tile option of tungsten armoured plasma facing components. Armour geometry resistant to the cascade effect failure was selected on the base of thermal and stress analyses. Experimental investigation of the LOTE has been performed also. Small size W/Cu mock-up withstood not only LOTE simulation load, but also survived afterwards for 1500 cycles at 26-28 MW/m 2 without damage in joint

  17. Defect production in simulated cascades: cascade quenching and short-term annealing

    International Nuclear Information System (INIS)

    Heinisch, H.L.

    1982-01-01

    Defect production in high energy displacement cascades has been modeled using the computer code MARLOWE to generate the cascades and the stochastic computer code ALSOME to simulate the cascade quenching and short-term annealing of isolated cascades. The quenching is accomplished by using ALSOME with exaggerated values for defect mobilities and critical reaction distanes for recombination and clustering, which are in effect until the number of defect pairs is equal to the value determined from resistivity experiments at 4K. Then normal mobilities and reaction distances are used during short-term annealing to a point representative of Stage III recovery. Effects of cascade interactions at low fluences are also being investigated. The quenching parameter values were empirically determined for 30 keV cascades. The results agree well with experimental information throughout the range from 1 keV to 100 keV. Even after quenching and short-term annealing the high energy cascades behave as a collection of lower energy subcascades and lobes. Cascades generated in a crystal having thermal displacements were found to be in better agreement with experiments after quenching and annealing than those generated in a non-thermal crystal

  18. The effects of self-interstitial clusters on cascade defect evolution beyond the primary damage state

    Energy Technology Data Exchange (ETDEWEB)

    Heinisch, H.L. [Pacific Northwest National Lab., Richland, WA (United States)

    1997-04-01

    The intracascade evolution of the defect distributions of cascades in copper is investigated using stochastic annealing simulations applied to cascades generated with molecular dynamics (MD). The temperature and energy dependencies of annihilation, clustering and free defect production are determined for individual cascades. The annealing simulation results illustrate the strong influence on intracascade evolution of the defect configuration existing in the primary damage state. Another factor significantly affecting the evolution of the defect distribution is the rapid one-dimensional diffusion of small, glissile interstitial loops produced directly in cascades. This phenomenon introduces a cascade energy dependence of defect evolution that is apparent only beyond the primary damage state, amplifying the need for further study of the annealing phase of cascade evolution and for performing many more MD cascade simulations at higher energies.

  19. The effects of self-interstitial clusters on cascade defect evolution beyond the primary damage state

    International Nuclear Information System (INIS)

    Heinisch, H.L.

    1997-01-01

    The intracascade evolution of the defect distributions of cascades in copper is investigated using stochastic annealing simulations applied to cascades generated with molecular dynamics (MD). The temperature and energy dependencies of annihilation, clustering and free defect production are determined for individual cascades. The annealing simulation results illustrate the strong influence on intracascade evolution of the defect configuration existing in the primary damage state. Another factor significantly affecting the evolution of the defect distribution is the rapid one-dimensional diffusion of small, glissile interstitial loops produced directly in cascades. This phenomenon introduces a cascade energy dependence of defect evolution that is apparent only beyond the primary damage state, amplifying the need for further study of the annealing phase of cascade evolution and for performing many more MD cascade simulations at higher energies

  20. Efficient collective influence maximization in cascading processes with first-order transitions

    Science.gov (United States)

    Pei, Sen; Teng, Xian; Shaman, Jeffrey; Morone, Flaviano; Makse, Hernán A.

    2017-01-01

    In many social and biological networks, the collective dynamics of the entire system can be shaped by a small set of influential units through a global cascading process, manifested by an abrupt first-order transition in dynamical behaviors. Despite its importance in applications, efficient identification of multiple influential spreaders in cascading processes still remains a challenging task for large-scale networks. Here we address this issue by exploring the collective influence in general threshold models of cascading process. Our analysis reveals that the importance of spreaders is fixed by the subcritical paths along which cascades propagate: the number of subcritical paths attached to each spreader determines its contribution to global cascades. The concept of subcritical path allows us to introduce a scalable algorithm for massively large-scale networks. Results in both synthetic random graphs and real networks show that the proposed method can achieve larger collective influence given the same number of seeds compared with other scalable heuristic approaches. PMID:28349988

  1. The lesioned brain: still a small world?

    Directory of Open Access Journals (Sweden)

    Linda Douw

    2010-11-01

    Full Text Available The intra-arterial amobarbital procedure (IAP or Wada test is used to determine language lateralization and contralateral memory functioning in patients eligible for neurosurgery because of pharmaco-resistant epilepsy. During unilateral sedation, functioning of the contralateral hemisphere is assessed by means of neuropsychological tests. We use the IAP as a reversible model for the effect of lesions on brain network topology. Three artifact free epochs (4096 samples were selected from each EEG record before and after amobarbital injection. Functional connectivity was assessed by means of the synchronization likelihood (SL. The resulting functional connectivity matrices were constructed for all six epochs per patient in four frequency bands, and weighted network analysis was performed. The clustering coefficient, average path length, small-world-index, and edge weight correlation were calculated. Recordings of 33 patients were available. Network topology changed significantly after amobarbital injection: clustering decreased in all frequency bands, while path length decreased in the theta and lower alpha band, indicating a shift towards a more random network topology. Likewise, the edge weight correlation decreased after injection of amobarbital in the theta and beta bands. Network characteristics after injection of amobarbital were correlated with memory score: higher theta band small-world-index and increased upper alpha path length were related to better memory score. The whole-brain network topology in patients eligible for epilepsy surgery becomes more random and less optimally organized after selective sedation of one hemisphere, as has been reported in studies with brain tumor patients. Furthermore, memory functioning after injection seems related to network topology, indicating that functional performance is related to topological network properties of the brain.

  2. Blackmail propagation on small-world networks

    Science.gov (United States)

    Shao, Zhi-Gang; Jian-Ping Sang; Zou, Xian-Wu; Tan, Zhi-Jie; Jin, Zhun-Zhi

    2005-06-01

    The dynamics of the blackmail propagation model based on small-world networks is investigated. It is found that for a given transmitting probability λ the dynamical behavior of blackmail propagation transits from linear growth type to logistical growth one with the network randomness p increases. The transition takes place at the critical network randomness pc=1/N, where N is the total number of nodes in the network. For a given network randomness p the dynamical behavior of blackmail propagation transits from exponential decrease type to logistical growth one with the transmitting probability λ increases. The transition occurs at the critical transmitting probability λc=1/, where is the average number of the nearest neighbors. The present work will be useful for understanding computer virus epidemics and other spreading phenomena on communication and social networks.

  3. On the agreement between small-world-like OFC model and real earthquakes

    International Nuclear Information System (INIS)

    Ferreira, Douglas S.R.; Papa, Andrés R.R.; Menezes, Ronaldo

    2015-01-01

    In this article we implemented simulations of the OFC model for earthquakes for two different topologies: regular and small-world, where in the latter the links are randomly rewired with probability p. In both topologies, we have studied the distribution of time intervals between consecutive earthquakes and the border effects present in each one. In addition, we also have characterized the influence that the probability p produces in certain characteristics of the lattice and in the intensity of border effects. From the two topologies, networks of consecutive epicenters were constructed, that allowed us to analyze the distribution of connectivities of each one. In our results distributions arise belonging to a family of non-traditional distributions functions, which agrees with previous studies using data from actual earthquakes. Our results reinforce the idea that the Earth is in a critical self-organized state and furthermore point towards temporal and spatial correlations between earthquakes in different places. - Highlights: • OFC model simulations for regular and small-world topologies. • For small-world topology distributions agree remarkably well with actual earthquakes. • Reinforce the idea of a critical self-organized state for the Earth's crust. • Point towards temporal and spatial correlations between far earthquakes in far places

  4. On the agreement between small-world-like OFC model and real earthquakes

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Douglas S.R., E-mail: douglas.ferreira@ifrj.edu.br [Instituto Federal de Educação, Ciência e Tecnologia do Rio de Janeiro, Paracambi, RJ (Brazil); Geophysics Department, Observatório Nacional, Rio de Janeiro, RJ (Brazil); Papa, Andrés R.R., E-mail: papa@on.br [Geophysics Department, Observatório Nacional, Rio de Janeiro, RJ (Brazil); Instituto de Física, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ (Brazil); Menezes, Ronaldo, E-mail: rmenezes@cs.fit.edu [BioComplex Laboratory, Computer Sciences, Florida Institute of Technology, Melbourne (United States)

    2015-03-20

    In this article we implemented simulations of the OFC model for earthquakes for two different topologies: regular and small-world, where in the latter the links are randomly rewired with probability p. In both topologies, we have studied the distribution of time intervals between consecutive earthquakes and the border effects present in each one. In addition, we also have characterized the influence that the probability p produces in certain characteristics of the lattice and in the intensity of border effects. From the two topologies, networks of consecutive epicenters were constructed, that allowed us to analyze the distribution of connectivities of each one. In our results distributions arise belonging to a family of non-traditional distributions functions, which agrees with previous studies using data from actual earthquakes. Our results reinforce the idea that the Earth is in a critical self-organized state and furthermore point towards temporal and spatial correlations between earthquakes in different places. - Highlights: • OFC model simulations for regular and small-world topologies. • For small-world topology distributions agree remarkably well with actual earthquakes. • Reinforce the idea of a critical self-organized state for the Earth's crust. • Point towards temporal and spatial correlations between far earthquakes in far places.

  5. Effects of spike-time-dependent plasticity on the stochastic resonance of small-world neuronal networks

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Haitao; Guo, Xinmeng; Wang, Jiang, E-mail: jiangwang@tju.edu.cn; Deng, Bin; Wei, Xile [School of Electrical Engineering and Automation, Tianjin University, Tianjin 300072 (China)

    2014-09-01

    The phenomenon of stochastic resonance in Newman-Watts small-world neuronal networks is investigated when the strength of synaptic connections between neurons is adaptively adjusted by spike-time-dependent plasticity (STDP). It is shown that irrespective of the synaptic connectivity is fixed or adaptive, the phenomenon of stochastic resonance occurs. The efficiency of network stochastic resonance can be largely enhanced by STDP in the coupling process. Particularly, the resonance for adaptive coupling can reach a much larger value than that for fixed one when the noise intensity is small or intermediate. STDP with dominant depression and small temporal window ratio is more efficient for the transmission of weak external signal in small-world neuronal networks. In addition, we demonstrate that the effect of stochastic resonance can be further improved via fine-tuning of the average coupling strength of the adaptive network. Furthermore, the small-world topology can significantly affect stochastic resonance of excitable neuronal networks. It is found that there exists an optimal probability of adding links by which the noise-induced transmission of weak periodic signal peaks.

  6. Effects of spike-time-dependent plasticity on the stochastic resonance of small-world neuronal networks

    International Nuclear Information System (INIS)

    Yu, Haitao; Guo, Xinmeng; Wang, Jiang; Deng, Bin; Wei, Xile

    2014-01-01

    The phenomenon of stochastic resonance in Newman-Watts small-world neuronal networks is investigated when the strength of synaptic connections between neurons is adaptively adjusted by spike-time-dependent plasticity (STDP). It is shown that irrespective of the synaptic connectivity is fixed or adaptive, the phenomenon of stochastic resonance occurs. The efficiency of network stochastic resonance can be largely enhanced by STDP in the coupling process. Particularly, the resonance for adaptive coupling can reach a much larger value than that for fixed one when the noise intensity is small or intermediate. STDP with dominant depression and small temporal window ratio is more efficient for the transmission of weak external signal in small-world neuronal networks. In addition, we demonstrate that the effect of stochastic resonance can be further improved via fine-tuning of the average coupling strength of the adaptive network. Furthermore, the small-world topology can significantly affect stochastic resonance of excitable neuronal networks. It is found that there exists an optimal probability of adding links by which the noise-induced transmission of weak periodic signal peaks

  7. Effects of in-cascade defect clustering on near-term defect evolution

    Energy Technology Data Exchange (ETDEWEB)

    Heinisch, H.L. [Pacific Northwest National Lab., Richland, WA (United States)

    1997-08-01

    The effects of in-cascade defect clustering on the nature of the subsequent defect population are being studied using stochastic annealing simulations applied to cascades generated in molecular dynamics (MD) simulations. The results of the simulations illustrates the strong influence of the defect configuration existing in the primary damage state on subsequent defect evolution. The large differences in mobility and stability of vacancy and interstitial defects and the rapid one-dimensional diffusion of small, glissile interstitial loops produced directly in cascades have been shown to be significant factors affecting the evolution of the defect distribution. In recent work, the effects of initial cluster sizes appear to be extremely important.

  8. Cascades and Dissipative Anomalies in Compressible Fluid Turbulence

    Directory of Open Access Journals (Sweden)

    Gregory L. Eyink

    2018-02-01

    Full Text Available We investigate dissipative anomalies in a turbulent fluid governed by the compressible Navier-Stokes equation. We follow an exact approach pioneered by Onsager, which we explain as a nonperturbative application of the principle of renormalization-group invariance. In the limit of high Reynolds and Péclet numbers, the flow realizations are found to be described as distributional or “coarse-grained” solutions of the compressible Euler equations, with standard conservation laws broken by turbulent anomalies. The anomalous dissipation of kinetic energy is shown to be due not only to local cascade but also to a distinct mechanism called pressure-work defect. Irreversible heating in stationary, planar shocks with an ideal-gas equation of state exemplifies the second mechanism. Entropy conservation anomalies are also found to occur via two mechanisms: an anomalous input of negative entropy (negentropy by pressure work and a cascade of negentropy to small scales. We derive “4/5th-law”-type expressions for the anomalies, which allow us to characterize the singularities (structure-function scaling exponents required to sustain the cascades. We compare our approach with alternative theories and empirical evidence. It is argued that the “Big Power Law in the Sky” observed in electron density scintillations in the interstellar medium is a manifestation of a forward negentropy cascade or an inverse cascade of usual thermodynamic entropy.

  9. Cascades and Dissipative Anomalies in Compressible Fluid Turbulence

    Science.gov (United States)

    Eyink, Gregory L.; Drivas, Theodore D.

    2018-02-01

    We investigate dissipative anomalies in a turbulent fluid governed by the compressible Navier-Stokes equation. We follow an exact approach pioneered by Onsager, which we explain as a nonperturbative application of the principle of renormalization-group invariance. In the limit of high Reynolds and Péclet numbers, the flow realizations are found to be described as distributional or "coarse-grained" solutions of the compressible Euler equations, with standard conservation laws broken by turbulent anomalies. The anomalous dissipation of kinetic energy is shown to be due not only to local cascade but also to a distinct mechanism called pressure-work defect. Irreversible heating in stationary, planar shocks with an ideal-gas equation of state exemplifies the second mechanism. Entropy conservation anomalies are also found to occur via two mechanisms: an anomalous input of negative entropy (negentropy) by pressure work and a cascade of negentropy to small scales. We derive "4 /5 th-law"-type expressions for the anomalies, which allow us to characterize the singularities (structure-function scaling exponents) required to sustain the cascades. We compare our approach with alternative theories and empirical evidence. It is argued that the "Big Power Law in the Sky" observed in electron density scintillations in the interstellar medium is a manifestation of a forward negentropy cascade or an inverse cascade of usual thermodynamic entropy.

  10. Cascade reactor: granule fabrication processes

    International Nuclear Information System (INIS)

    Erlandson, O.D.; Winkler, E.O.; Maya, I.; Pitts, J.H.

    1985-01-01

    A key feature of Cascade is the granular blanket. Of the many blanket material options open to Cascade, fabrication of Li 2 O granules was felt to offer the greatest challenge. The authors explored available methods for initial Li 2 O granule fabrication. They identified three cost-effective processes for fabricating Li 2 O granules: the VSM drop-melt furnace process, which is based on melting and spheroidizing irregularly shaped Li 2 O feed granules; the LiOH process, which spheroidizes liquefied LiOH and uses GA Technologies' sphere-forming procedures; and the Li 2 CO 3 sol-gel process, used for making spherical fuel particles for the high-temperature gas-cooled reactor (HTGR). Each process is described below

  11. Information cascade on networks

    Science.gov (United States)

    Hisakado, Masato; Mori, Shintaro

    2016-05-01

    In this paper, we discuss a voting model by considering three different kinds of networks: a random graph, the Barabási-Albert (BA) model, and a fitness model. A voting model represents the way in which public perceptions are conveyed to voters. Our voting model is constructed by using two types of voters-herders and independents-and two candidates. Independents conduct voting based on their fundamental values; on the other hand, herders base their voting on the number of previous votes. Hence, herders vote for the majority candidates and obtain information relating to previous votes from their networks. We discuss the difference between the phases on which the networks depend. Two kinds of phase transitions, an information cascade transition and a super-normal transition, were identified. The first of these is a transition between a state in which most voters make the correct choices and a state in which most of them are wrong. The second is a transition of convergence speed. The information cascade transition prevails when herder effects are stronger than the super-normal transition. In the BA and fitness models, the critical point of the information cascade transition is the same as that of the random network model. However, the critical point of the super-normal transition disappears when these two models are used. In conclusion, the influence of networks is shown to only affect the convergence speed and not the information cascade transition. We are therefore able to conclude that the influence of hubs on voters' perceptions is limited.

  12. Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells

    Energy Technology Data Exchange (ETDEWEB)

    Voss, Kelsey; Amaya, Moushimi [National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, 10650 Pyramid Place, Manassas, VA (United States); Mueller, Claudius [Center for Applied Proteomics and Personalized Medicine, George Mason University, 10900 University Boulevard, Manassas, VA (United States); Roberts, Brian [Leidos Health Life Sciences, 5202 Presidents Court, Suite 110, Frederick, MD (United States); Kehn-Hall, Kylene; Bailey, Charles [National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, 10650 Pyramid Place, Manassas, VA (United States); Petricoin, Emanuel [Center for Applied Proteomics and Personalized Medicine, George Mason University, 10900 University Boulevard, Manassas, VA (United States); Narayanan, Aarthi, E-mail: anaraya1@gmu.edu [National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, 10650 Pyramid Place, Manassas, VA (United States)

    2014-11-15

    New World alphaviruses belonging to the family Togaviridae are classified as emerging infectious agents and Category B select agents. Our study is focused on the role of the host extracellular signal-regulated kinase (ERK) in the infectious process of New World alphaviruses. Infection of human cells by Venezuelan equine encephalitis virus (VEEV) results in the activation of the ERK-signaling cascade. Inhibition of ERK1/2 by the small molecule inhibitor Ag-126 results in inhibition of viral multiplication. Ag-126-mediated inhibition of VEEV was due to potential effects on early and late stages of the infectious process. While expression of viral proteins was down-regulated in Ag-126 treated cells, we did not observe any influence of Ag-126 on the nuclear distribution of capsid. Finally, Ag-126 exerted a broad-spectrum inhibitory effect on New World alphavirus multiplication, thus indicating that the host kinase, ERK, is a broad-spectrum candidate for development of novel therapeutics against New World alphaviruses. - Highlights: • VEEV infection activated multiple components of the ERK signaling cascade. • Inhibition of ERK activation using Ag-126 inhibited VEEV multiplication. • Activation of ERK by Ceramide C6 increased infectious titers of TC-83. • Ag-126 inhibited virulent strains of all New World alphaviruses. • Ag-126 treatment increased percent survival of infected cells.

  13. Inhibition of host extracellular signal-regulated kinase (ERK) activation decreases new world alphavirus multiplication in infected cells

    International Nuclear Information System (INIS)

    Voss, Kelsey; Amaya, Moushimi; Mueller, Claudius; Roberts, Brian; Kehn-Hall, Kylene; Bailey, Charles; Petricoin, Emanuel; Narayanan, Aarthi

    2014-01-01

    New World alphaviruses belonging to the family Togaviridae are classified as emerging infectious agents and Category B select agents. Our study is focused on the role of the host extracellular signal-regulated kinase (ERK) in the infectious process of New World alphaviruses. Infection of human cells by Venezuelan equine encephalitis virus (VEEV) results in the activation of the ERK-signaling cascade. Inhibition of ERK1/2 by the small molecule inhibitor Ag-126 results in inhibition of viral multiplication. Ag-126-mediated inhibition of VEEV was due to potential effects on early and late stages of the infectious process. While expression of viral proteins was down-regulated in Ag-126 treated cells, we did not observe any influence of Ag-126 on the nuclear distribution of capsid. Finally, Ag-126 exerted a broad-spectrum inhibitory effect on New World alphavirus multiplication, thus indicating that the host kinase, ERK, is a broad-spectrum candidate for development of novel therapeutics against New World alphaviruses. - Highlights: • VEEV infection activated multiple components of the ERK signaling cascade. • Inhibition of ERK activation using Ag-126 inhibited VEEV multiplication. • Activation of ERK by Ceramide C6 increased infectious titers of TC-83. • Ag-126 inhibited virulent strains of all New World alphaviruses. • Ag-126 treatment increased percent survival of infected cells

  14. Annealing simulation of cascade damage using MARLOWE-DAIQUIRI codes

    International Nuclear Information System (INIS)

    Muroga, Takeo

    1984-01-01

    The localization effect of the defects generated by the cascade damage on the properties of solids was studied by using a computer code. The code is based on the two-body collision approximation method and the Monte Carlo method. The MARLOWE and DAIQUIRI codes were partly improved to fit the present calculation of the annealing of cascade damage. The purpose of this study is to investigate the behavior of defects under the simulated reactive and irradiation condition. Calculation was made for alpha iron (BCC), and the threshold energy was set at 40 eV. The temperature dependence of annealing and the growth of a cluster were studied. The overlapping effect of cascade was studied. At first, the extreme case of overlapping was studied, then the practical cases were estimated by interpolation. The state of overlapping of cascade corresponded to the irradiation speed. The interaction between cascade and dislocations was studied, and the calculation of the annealing of primary knock-out atoms (PKA) in alpha iron was performed. At low temperature, the effect of dislocations was large, but the growth of vacancy was not seen. At high temperature, the effect of dislocations was small. The evaluation of the simulation of various ion irradiation and the growth efficiency of defects were performed. (Kato, T.)

  15. Structure of Small World Innovation Network and Learning Performance

    Directory of Open Access Journals (Sweden)

    Shuang Song

    2014-01-01

    Full Text Available This paper examines the differences of learning performance of 5 MNCs (multinational corporations that filed the largest number of patents in China. We establish the innovation network with the patent coauthorship data by these 5 MNCs and classify the networks by the tail of distribution curve of connections. To make a comparison of the learning performance of these 5 MNCs with differing network structures, we develop an organization learning model by regarding the reality as having m dimensions, which denotes the heterogeneous knowledge about the reality. We further set n innovative individuals that are mutually interactive and own unique knowledge about the reality. A longer (shorter distance between the knowledge of the individual and the reality denotes a lower (higher knowledge level of that individual. Individuals interact with and learn from each other within the small-world network. By making 1,000 numerical simulations and averaging the simulated results, we find that the differing structure of the small-world network leads to the differences of learning performance between these 5 MNCs. The network monopolization negatively impacts and network connectivity positively impacts learning performance. Policy implications in the conclusion section suggest that to improve firm learning performance, it is necessary to establish a flat and connective network.

  16. Effects of small-world connectivity on noise-induced temporal and spatial order in neural media

    International Nuclear Information System (INIS)

    Perc, Matjaz

    2007-01-01

    We present an overview of possible effects of small-world connectivity on noise-induced temporal and spatial order in a two-dimensional network of excitable neural media with FitzHugh-Nagumo local dynamics. Small-world networks are characterized by a given fraction of so-called long-range couplings or shortcut links that connect distant units of the system, while all other units are coupled in a diffusive-like manner. Interestingly, already a small fraction of these long-range couplings can have wide-ranging effects on the temporal as well as spatial noise-induced dynamics of the system. Here we present two main effects. First, we show that the temporal order, characterized by the autocorrelation of a firing-rate function, can be greatly enhanced by the introduction of small-world connectivity, whereby the effect increases with the increasing fraction of introduced shortcut links. Second, we show that the introduction of long-range couplings induces disorder of otherwise ordered, spiral-wave-like, noise-induced patterns that can be observed by exclusive diffusive connectivity of spatial units. Thereby, already a small fraction of shortcut links is sufficient to destroy coherent pattern formation in the media. Although the two results seem contradictive, we provide an explanation considering the inherent scale-free nature of small-world networks, which on one hand, facilitates signal transduction and thus temporal order in the system, whilst on the other hand, disrupts the internal spatial scale of the media thereby hindering the existence of coherent wave-like patterns. Additionally, the importance of spatially versus temporally ordered neural network functioning is discussed

  17. Trophic cascades linking wolves (Canis lupus), coyotes (Canis latrans), and small mammals

    Science.gov (United States)

    Miller, B.J.; Harlow, H.J.; Harlow, T.S.; Biggins, D.; Ripple, W.J.

    2012-01-01

    When large carnivores are extirpated from ecosystems that evolved with apex predators, these systems can change at the herbivore and plant trophic levels. Such changes across trophic levels are called cascading effects and they are very important to conservation. Studies on the effects of reintroduced wolves in Yellowstone National Park have examined the interaction pathway of wolves (Canis lupus L., 1758) to ungulates to plants. This study examines the interaction effects of wolves to coyotes to rodents (reversing mesopredator release in the absence of wolves). Coyotes (Canis latrans Say, 1823) generally avoided areas near a wolf den. However, when in the proximity of a den, they used woody habitats (pine or sage) compared with herbaceous habitats (grass or forb or sedge)- when they were away from the wolf den. Our data suggested a significant increase in rodent numbers, particularly voles (genus Microtus Schrank, 1798), during the 3-year study on plots that were within 3 km of the wolf den, but we did not detect a significant change in rodent numbers over time for more distant plots. Predation by coyotes may have depressed numbers of small mammals in areas away from the wolf den. These factors indicate a top-down effect by wolves on coyotes and subsequently on the rodents of the area. Restoration of wolves could be a powerful tool for regulating predation at lower trophic levels.

  18. Computer simulation of displacement cascade structures in D-T neutron-irradiated Au, Ag, Cu, Ni and Al with the MARLOWE code

    International Nuclear Information System (INIS)

    Watanabe, N.; Nishiguchi, R.; Shimomura, Y.

    1991-01-01

    Spatial distribution of point defects in displacement damage cascades at the early stage of their formation was simulated with the MARLOWE code for primary knock-on atoms which is relevant to D-T neutron irradiation. Calculations were carried out for Au, Ag, Cu, Ni and Al. Computer-simulated results were analyzed with complement of TEM observations of D-T neutron-irradiated metals at low temperature. The spatial configuration of displacement cascades, the size of small vacancy aggregates and the size of displacement damage cascade were examined. Results suggest that most of vacancy clusters which were formed in damage cascades may be as small as below 20 vacancies. The remarkable difference in defect yield of cascade damage in Ni and Cu is due to interstitial cluster formation and main contribution of cascade energy overlapping observed in cryotransfer TEM of D-T neutron-irradiated Au is due to ejected interstitials from cascade cores. (orig.)

  19. Small-World and Scale-Free Network Models for IoT Systems

    Directory of Open Access Journals (Sweden)

    Insoo Sohn

    2017-01-01

    Full Text Available It is expected that Internet of Things (IoT revolution will enable new solutions and business for consumers and entrepreneurs by connecting billions of physical world devices with varying capabilities. However, for successful realization of IoT, challenges such as heterogeneous connectivity, ubiquitous coverage, reduced network and device complexity, enhanced power savings, and enhanced resource management have to be solved. All these challenges are heavily impacted by the IoT network topology supported by massive number of connected devices. Small-world networks and scale-free networks are important complex network models with massive number of nodes and have been actively used to study the network topology of brain networks, social networks, and wireless networks. These models, also, have been applied to IoT networks to enhance synchronization, error tolerance, and more. However, due to interdisciplinary nature of the network science, with heavy emphasis on graph theory, it is not easy to study the various tools provided by complex network models. Therefore, in this paper, we attempt to introduce basic concepts of graph theory, including small-world networks and scale-free networks, and provide system models that can be easily implemented to be used as a powerful tool in solving various research problems related to IoT.

  20. A fault-tolerant small world topology control model in ad hoc networks for search and rescue

    Science.gov (United States)

    Tan, Mian; Fang, Ling; Wu, Yue; Zhang, Bo; Chang, Bowen; Holme, Petter; Zhao, Jing

    2018-02-01

    Due to their self-organized, multi-hop and distributed characteristics, ad hoc networks are useful in search and rescue. Topology control models need to be designed for energy-efficient, robust and fast communication in ad hoc networks. This paper proposes a topology control model which specializes for search and rescue-Compensation Small World-Repeated Game (CSWRG)-which integrates mobility models, constructing small world networks and a game-theoretic approach to the allocation of resources. Simulation results show that our mobility models can enhance the communication performance of the constructed small-world networks. Our strategy, based on repeated game, can suppress selfish behavior and compensate agents that encounter selfish or faulty neighbors. This model could be useful for the design of ad hoc communication networks.

  1. Interrelation of structure and operational states in cascading failure of overloading lines in power grids

    Science.gov (United States)

    Xue, Fei; Bompard, Ettore; Huang, Tao; Jiang, Lin; Lu, Shaofeng; Zhu, Huaiying

    2017-09-01

    As the modern power system is expected to develop to a more intelligent and efficient version, i.e. the smart grid, or to be the central backbone of energy internet for free energy interactions, security concerns related to cascading failures have been raised with consideration of catastrophic results. The researches of topological analysis based on complex networks have made great contributions in revealing structural vulnerabilities of power grids including cascading failure analysis. However, existing literature with inappropriate assumptions in modeling still cannot distinguish the effects between the structure and operational state to give meaningful guidance for system operation. This paper is to reveal the interrelation between network structure and operational states in cascading failure and give quantitative evaluation by integrating both perspectives. For structure analysis, cascading paths will be identified by extended betweenness and quantitatively described by cascading drop and cascading gradient. Furthermore, the operational state for cascading paths will be described by loading level. Then, the risk of cascading failure along a specific cascading path can be quantitatively evaluated considering these two factors. The maximum cascading gradient of all possible cascading paths can be used as an overall metric to evaluate the entire power grid for its features related to cascading failure. The proposed method is tested and verified on IEEE30-bus system and IEEE118-bus system, simulation evidences presented in this paper suggests that the proposed model can identify the structural causes for cascading failure and is promising to give meaningful guidance for the protection of system operation in the future.

  2. Identifying New Small Proteins in Escherichia coli.

    Science.gov (United States)

    VanOrsdel, Caitlin E; Kelly, John P; Burke, Brittany N; Lein, Christina D; Oufiero, Christopher E; Sanchez, Joseph F; Wimmers, Larry E; Hearn, David J; Abuikhdair, Fatimeh J; Barnhart, Kathryn R; Duley, Michelle L; Ernst, Sarah E G; Kenerson, Briana A; Serafin, Aubrey J; Hemm, Matthew R

    2018-04-12

    The number of small proteins (SPs) encoded in the Escherichia coli genome is unknown, as current bioinformatics and biochemical techniques make short gene and small protein identification challenging. One method of small protein identification involves adding an epitope tag to the 3' end of a short open reading frame (sORF) on the chromosome, with synthesis confirmed by immunoblot assays. In this study, this strategy was used to identify new E. coli small proteins, tagging 80 sORFs in the E. coli genome, and assayed for protein synthesis. The selected sORFs represent diverse sequence characteristics, including degrees of sORF conservation, predicted transmembrane domains, sORF direction with respect to flanking genes, ribosome binding site (RBS) prediction, and ribosome profiling results. Of 80 sORFs, 36 resulted in encoded synthesized proteins-a 45% success rate. Modeling of detected versus non-detected small proteins analysis showed predictions based on RBS prediction, transcription data, and ribosome profiling had statistically-significant correlation with protein synthesis; however, there was no correlation between current sORF annotation and protein synthesis. These results suggest substantial numbers of small proteins remain undiscovered in E. coli, and existing bioinformatics techniques must continue to improve to facilitate identification. © 2018 The Authors. Proteomics Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, Towson University.

  3. Quadrotor trajectory tracking using PID cascade control

    Science.gov (United States)

    Idres, M.; Mustapha, O.; Okasha, M.

    2017-12-01

    Quadrotors have been applied to collect information for traffic, weather monitoring, surveillance and aerial photography. In order to accomplish their mission, quadrotors have to follow specific trajectories. This paper presents proportional-integral-derivative (PID) cascade control of a quadrotor for path tracking problem when velocity and acceleration are small. It is based on near hover controller for small attitude angles. The integral of time-weighted absolute error (ITAE) criterion is used to determine the PID gains as a function of quadrotor modeling parameters. The controller is evaluated in three-dimensional environment in Simulink. Overall, the tracking performance is found to be excellent for small velocity condition.

  4. Cascading off the West Greenland Shelf: A numerical perspective

    Science.gov (United States)

    Marson, Juliana M.; Myers, Paul G.; Hu, Xianmin; Petrie, Brian; Azetsu-Scott, Kumiko; Lee, Craig M.

    2017-07-01

    Cascading of dense water from the shelf to deeper layers of the adjacent ocean basin has been observed in several locations around the world. The West Greenland Shelf (WGS), however, is a region where this process has never been documented. In this study, we use a numerical model with a 1/4° resolution to determine (i) if cascading could happen from the WGS; (ii) where and when it could take place; (iii) the forcings that induce or halt this process; and (iv) the path of the dense plume. Results show cascading happening off the WGS at Davis Strait. Dense waters form there due to brine rejection and slide down the slope during spring. Once the dense plume leaves the shelf, it gradually mixes with waters of similar density and moves northward into Baffin Bay. Our simulation showed events happening between 2003-2006 and during 2014; but no plume was observed in the simulation between 2007 and 2013. We suggest that the reason why cascading was halted in this period is related to: the increased freshwater transport from the Arctic Ocean through Fram Strait; the additional sea ice melting in the region; and the reduced presence of Irminger Water at Davis Strait during fall/early winter. Although observations at Davis Strait show that our simulation usually overestimates the seasonal range of temperature and salinity, they agree with the overall variability captured by the model. This suggests that cascades have the potential to develop on the WGS, albeit less dense than the ones estimated by the simulation.

  5. Assessment of the world market for small and medium reactors

    International Nuclear Information System (INIS)

    Csik, B.J.

    2000-01-01

    In the past decades, the major focus for nuclear power has been the design and construction of nuclear plants of ever increasing size. This was appropriate for many industrialized countries, which could readily add generation capability to their electrical grids in large increments. However, recently there has been an increasing emphasis on the development of small and medium reactors especially to meet needs in developing countries where electrical grids cannot accept the additional capacity of a large nuclear plant. The paper presents an estimation of the world market for small and medium sized reactors giving the basic assumptions, criteria, scope, methods and important factors. (author)

  6. Small-world topology of functional connectivity in randomly connected dynamical systems

    Czech Academy of Sciences Publication Activity Database

    Hlinka, Jaroslav; Hartman, David; Paluš, Milan

    2012-01-01

    Roč. 22, č. 3 (2012), art no 033107 ISSN 1054-1500 R&D Projects: GA ČR GCP103/11/J068 Institutional support: RVO:67985807 Keywords : graph theory * nonlinear dynamical systems * small-world networks Subject RIV: BB - Applied Statistics, Operational Research Impact factor: 2.188, year: 2012

  7. Evaluating the transport in small-world and scale-free networks

    International Nuclear Information System (INIS)

    Juárez-López, R.; Obregón-Quintana, B.; Hernández-Pérez, R.; Reyes-Ramírez, I.; Guzmán-Vargas, L.

    2014-01-01

    We present a study of some properties of transport in small-world and scale-free networks. Particularly, we compare two types of transport: subject to friction (electrical case) and in the absence of friction (maximum flow). We found that in clustered networks based on the Watts–Strogatz (WS) model, for both transport types the small-world configurations exhibit the best trade-off between local and global levels. For non-clustered WS networks the local transport is independent of the rewiring parameter, while the transport improves globally. Moreover, we analyzed both transport types in scale-free networks considering tendencies in the assortative or disassortative mixing of nodes. We construct the distribution of the conductance G and flow F to evaluate the effects of the assortative (disassortative) mixing, finding that for scale-free networks, as we introduce different levels of the degree–degree correlations, the power-law decay in the conductances is altered, while for the flow, the power-law tail remains unchanged. In addition, we analyze the effect on the conductance and the flow of the minimum degree and the shortest path between the source and destination nodes, finding notable differences between these two types of transport

  8. Modeling of cascade and sub-cascade formation at high pka energies in irradiated fusion structural materials

    International Nuclear Information System (INIS)

    Ryazanov, A.; Metelkin, E.V.; Semenov, E.A.

    2007-01-01

    Full text of publication follows: A new theoretical model is developed for the investigations of cascade and sub-cascade formation in fusion structural materials under fast neutron irradiation at high primary knock atom (PKA) energies. Under 14 MeV neutron irradiation especially of light fusion structural materials such as Be, C, SiC materials PKA will have the energies up to 1 MeV. At such high energies it is very difficult to use the Monte Carlo or molecular dynamic simulations. The developed model is based on the analytical consideration of elastic collisions between displaced moving atoms into atomic cascades produced by a PKAs with the some kinetic energy obtained from fast neutrons. The Tomas-Fermy interaction potential is used for the describing of elastic collisions between moving atoms. The suggested model takes into account also the electronic losses for moving atoms between elastic collisions. The self consistent criterion for sub-cascade formation is suggested here which is based on the comparison of mean distance between two consequent PKA collisions and size of sub-cascade produced by PKA. The analytical relations for the most important characteristics of cascades and sub-cascade are determined including the average number of sub-cascades per one PKA in the dependence on PKA energy, the distance between sub-cascades and the average cascade and sub-cascade sizes as a function of PKA energy. The developed model allows determining the total numbers, distribution functions of cascades and sub-cascades in dependence on their sizes and generation rate of cascades and sub-cascades for different fusion neutron energy spectra. Based on the developed model the numerical calculations for main characteristics of cascades and sub-cascades in different fusion structural materials are performed using the neutron flux and PKA energy spectra for fusion reactors: ITER and DEMO. The main characteristics for cascade and sub-cascade formation are calculated here for the

  9. Atom-atom collision cascades localization

    International Nuclear Information System (INIS)

    Kirsanov, V.V.

    1980-01-01

    The presence of an impurity and thermal vibration influence on the atom-atom collision cascade development is analysed by the computer simulation method (the modificated dynamic model). It is discovered that the relatively low energetic cascades are localized with the temperature increase of an irradiated crystal. On the basis of the given effect the mechanism of splitting of the high energetic cascades into subcascades is proposed. It accounts for two factors: the primary knocked atom energy and the irradiated crystal temperature. Introduction of an impurity also localizes the cascades independently from the impurity atom mass. The cascades localization leads to intensification of the process of annealing in the cascades and reduction of the post-cascade vacancy cluster sizes. (author)

  10. Stochastic resonance in small-world neuronal networks with hybrid electrical–chemical synapses

    International Nuclear Information System (INIS)

    Wang, Jiang; Guo, Xinmeng; Yu, Haitao; Liu, Chen; Deng, Bin; Wei, Xile; Chen, Yingyuan

    2014-01-01

    Highlights: •We study stochastic resonance in small-world neural networks with hybrid synapses. •The resonance effect depends largely on the probability of chemical synapse. •An optimal chemical synapse probability exists to evoke network resonance. •Network topology affects the stochastic resonance in hybrid neuronal networks. - Abstract: The dependence of stochastic resonance in small-world neuronal networks with hybrid electrical–chemical synapses on the probability of chemical synapse and the rewiring probability is investigated. A subthreshold periodic signal is imposed on one single neuron within the neuronal network as a pacemaker. It is shown that, irrespective of the probability of chemical synapse, there exists a moderate intensity of external noise optimizing the response of neuronal networks to the pacemaker. Moreover, the effect of pacemaker driven stochastic resonance of the system depends largely on the probability of chemical synapse. A high probability of chemical synapse will need lower noise intensity to evoke the phenomenon of stochastic resonance in the networked neuronal systems. In addition, for fixed noise intensity, there is an optimal chemical synapse probability, which can promote the propagation of the localized subthreshold pacemaker across neural networks. And the optimal chemical synapses probability turns even larger as the coupling strength decreases. Furthermore, the small-world topology has a significant impact on the stochastic resonance in hybrid neuronal networks. It is found that increasing the rewiring probability can always enhance the stochastic resonance until it approaches the random network limit

  11. World trend - a 10% growth per year for small wind turbines

    International Nuclear Information System (INIS)

    Kane, M.

    2016-01-01

    A decline was expected for small wind turbine business with the advent of bigger wind turbines but it is really not the case. In 2014 the growth rate was about 10 % with a cumulated power installed that year of 830 MW for small wind turbines. China (41% of the installed capacity), United-States (30%) and Great-Britain (15%) are the 3 main players. About 1 million wind turbines are operating in the world - it means 8.3% (∼ 70.000 units) more than a year before. (A.C.)

  12. Small-molecule inhibitors of toxT expression in Vibrio cholerae.

    Science.gov (United States)

    Anthouard, Rebecca; DiRita, Victor J

    2013-08-06

    Vibrio cholerae, a Gram-negative bacterium, infects humans and causes cholera, a severe disease characterized by vomiting and diarrhea. These symptoms are primarily caused by cholera toxin (CT), whose production by V. cholerae is tightly regulated by the virulence cascade. In this study, we designed and carried out a high-throughput chemical genetic screen to identify inhibitors of the virulence cascade. We identified three compounds, which we named toxtazin A and toxtazin B and B', representing two novel classes of toxT transcription inhibitors. All three compounds reduce production of both CT and the toxin-coregulated pilus (TCP), an important colonization factor. We present evidence that toxtazin A works at the level of the toxT promoter and that toxtazins B and B' work at the level of the tcpP promoter. Treatment with toxtazin B results in a 100-fold reduction in colonization in an infant mouse model of infection, though toxtazin A did not reduce colonization at the concentrations tested. These results add to the growing body of literature indicating that small-molecule inhibitors of virulence genes could be developed to treat infections, as alternatives to antibiotics become increasingly needed. V. cholerae caused more than 580,000 infections worldwide in 2011 alone (WHO, Wkly. Epidemiol. Rec. 87:289-304, 2012). Cholera is treated with an oral rehydration therapy consisting of water, glucose, and electrolytes. However, as V. cholerae is transmitted via contaminated water, treatment can be difficult for communities whose water source is contaminated. In this study, we address the need for new therapeutic approaches by targeting the production of the main virulence factor, cholera toxin (CT). The high-throughput screen presented here led to the identification of two novel classes of inhibitors of the virulence cascade in V. cholerae, toxtazin A and toxtazins B and B'. We demonstrate that (i) small-molecule inhibitors of virulence gene production can be

  13. Quasi-experiments to establish causal effects of HIV care and treatment and to improve the cascade of care

    Science.gov (United States)

    Bor, Jacob; Geldsetzer, Pascal; Venkataramani, Atheendar; Bärnighausen, Till

    2015-01-01

    Purpose of review Randomized, population-representative trials of clinical interventions are rare. Quasi-experiments have been used successfully to generate causal evidence on the cascade of HIV care in a broad range of real-world settings. Recent findings Quasi-experiments exploit exogenous, or quasi-random, variation occurring naturally in the world or because of an administrative rule or policy change to estimate causal effects. Well designed quasi-experiments have greater internal validity than typical observational research designs. At the same time, quasi-experiments may also have potential for greater external validity than experiments and can be implemented when randomized clinical trials are infeasible or unethical. Quasi-experimental studies have established the causal effects of HIV testing and initiation of antiretroviral therapy on health, economic outcomes and sexual behaviors, as well as indirect effects on other community members. Recent quasi-experiments have evaluated specific interventions to improve patient performance in the cascade of care, providing causal evidence to optimize clinical management of HIV. Summary Quasi-experiments have generated important data on the real-world impacts of HIV testing and treatment and on interventions to improve the cascade of care. With the growth in large-scale clinical and administrative data, quasi-experiments enable rigorous evaluation of policies implemented in real-world settings. PMID:26371463

  14. Quasi-experiments to establish causal effects of HIV care and treatment and to improve the cascade of care.

    Science.gov (United States)

    Bor, Jacob; Geldsetzer, Pascal; Venkataramani, Atheendar; Bärnighausen, Till

    2015-11-01

    Randomized, population-representative trials of clinical interventions are rare. Quasi-experiments have been used successfully to generate causal evidence on the cascade of HIV care in a broad range of real-world settings. Quasi-experiments exploit exogenous, or quasi-random, variation occurring naturally in the world or because of an administrative rule or policy change to estimate causal effects. Well designed quasi-experiments have greater internal validity than typical observational research designs. At the same time, quasi-experiments may also have potential for greater external validity than experiments and can be implemented when randomized clinical trials are infeasible or unethical. Quasi-experimental studies have established the causal effects of HIV testing and initiation of antiretroviral therapy on health, economic outcomes and sexual behaviors, as well as indirect effects on other community members. Recent quasi-experiments have evaluated specific interventions to improve patient performance in the cascade of care, providing causal evidence to optimize clinical management of HIV. Quasi-experiments have generated important data on the real-world impacts of HIV testing and treatment and on interventions to improve the cascade of care. With the growth in large-scale clinical and administrative data, quasi-experiments enable rigorous evaluation of policies implemented in real-world settings.

  15. The relationship between collisional phase defect distribution and cascade collapse efficiency

    International Nuclear Information System (INIS)

    Morishita, K.; Heinisch, H.L.; Ishino, S.; Sekimura, N.

    1994-01-01

    Defect distributions after the collisional phase of cascade damage processes were calculated using the computer simulation code MARLOWE, which is based on the binary collision approximation. The densities of vacant sites were evaluated in defect-dense regions at the end of the collisional phase in simulated ion irradiations of several pure metals (Au, Ag, Cu, Ni, Fe, Mo and W). The vacancy density distributions were compared to the measured cascade collapse efficiencies obtained from low-dose ion irradiations of thin foils reported in the literature to identify the minimum or ''critical'' values of the vacancy densities during the collisional phase corresponding to cascade collapse. The critical densities are generally independent of the cascade energy in the same metal. The relationships between physical properties of the target elements and the critical densities are discussed within the framework of the cascade thermal spike model. ((orig.))

  16. Structural basis for CRISPR RNA-guided DNA recognition by Cascade

    NARCIS (Netherlands)

    Jore, M.M.; Lundgren, N.M.J.; Duijn, van E.; Bultema, J.B.; Westra, E.R.; Oost, van der J.; Brouns, S.J.J.; Beijer, M.R.

    2011-01-01

    The CRISPR (clustered regularly interspaced short palindromic repeats) immune system in prokaryotes uses small guide RNAs to neutralize invading viruses and plasmids. In Escherichia coli, immunity depends on a ribonucleoprotein complex called Cascade. Here we present the composition and

  17. Structural basis for CRISPR RNA-guided DNA recognition by Cascade

    NARCIS (Netherlands)

    Jore, Matthijs M.; Lundgren, Magnus; van Duijn, Esther; Bultema, Jelle B.; Westra, Edze R.; Waghmare, Sakharam P.; Wiedenheft, Blake; Pul, Uemit; Wurm, Reinhild; Wagner, Rolf; Beijer, Marieke R.; Barendregt, Arjan; Zhou, Kaihong; Snijders, Ambrosius P. L.; Dickman, Mark J.; Doudna, Jennifer A.; Boekema, Egbert J.; Heck, Albert J. R.; van der Oost, John; Brouns, Stan J. J.; Pul, Ümit

    The CRISPR (clustered regularly interspaced short palindromic repeats) immune system in prokaryotes uses small guide RNAs to neutralize invading viruses and plasmids. In Escherichia coli, immunity depends on a ribonucleoprotein complex called Cascade. Here we present the composition and

  18. Effects of temperature in binary-collision simulations of high-energy displacement cascades

    International Nuclear Information System (INIS)

    Heinisch, H.L.

    1981-10-01

    Several hundred cascades ranging from 1 to 500 keV were generated using the binary collision code MARLOWE for primary knock-on atoms (PKAs) with randomly chosen directions in both a non-thermal copper lattice and one having atomic displacements representative of room temperature. To simulate the recombination occurring during localized quenching of the highly excited cascade region, an effective spontaneous recombination radius was applied to reduce the number of defect pairs to be consistent with values extracted from resistivity measurements at 4 0 K. At room temperature fewer widely separated pairs are produced, thus the recombination radius is smaller, however, the recombination radii were found to be independent of energy over the entire energy range investigated for both the cold and room temperature cases. The sizes and other features of the point defect distributions were determined as a function of energy. Differences between cold and room temperature cascade dimensions are small. The room temperature cascades tend to have a greater number of distinct damage regions per cascade, with about the same frequency of widely separated subcascades

  19. Cascade-robustness optimization of coupling preference in interconnected networks

    International Nuclear Information System (INIS)

    Zhang, Xue-Jun; Xu, Guo-Qiang; Zhu, Yan-Bo; Xia, Yong-Xiang

    2016-01-01

    Highlights: • A specific memetic algorithm was proposed to optimize coupling links. • A small toy model was investigated to examine the underlying mechanism. • The MA optimized strategy exhibits a moderate assortative pattern. • A novel coupling coefficient index was proposed to quantify coupling preference. - Abstract: Recently, the robustness of interconnected networks has attracted extensive attentions, one of which is to investigate the influence of coupling preference. In this paper, the memetic algorithm (MA) is employed to optimize the coupling links of interconnected networks. Afterwards, a comparison is made between MA optimized coupling strategy and traditional assortative, disassortative and random coupling preferences. It is found that the MA optimized coupling strategy with a moderate assortative value shows an outstanding performance against cascading failures on both synthetic scale-free interconnected networks and real-world networks. We then provide an explanation for this phenomenon from a micro-scope point of view and propose a coupling coefficient index to quantify the coupling preference. Our work is helpful for the design of robust interconnected networks.

  20. Phase multistability in a dynamical small world network

    Energy Technology Data Exchange (ETDEWEB)

    Shabunin, A. V., E-mail: shabuninav@info.sgu.ru [Radiophysics and Nonlinear Dynamics Department, Saratov State University, Saratov (Russian Federation)

    2015-01-15

    The effect of phase multistability is explored in a small world network of periodic oscillators with diffusive couplings. The structure of the network represents a ring with additional non-local links, which spontaneously arise and vanish between arbitrary nodes. The dynamics of random couplings is modeled by “birth” and “death” stochastic processes by means of the cellular automate approach. The evolution of the network under gradual increasing of the number of random couplings goes through stages of phases fluctuations and spatial cluster formation. Finally, in the presence of non-local couplings the phase multistability “dies” and only the in-phase regime survives.

  1. Mechanisms of cascade collapse

    International Nuclear Information System (INIS)

    Diaz de la Rubia, T.; Smalinskas, K.; Averback, R.S.; Robertson, I.M.; Hseih, H.; Benedek, R.

    1988-12-01

    The spontaneous collapse of energetic displacement cascades in metals into vacancy dislocation loops has been investigated by molecular dynamics (MD) computer simulation and transmission electron microscopy (TEM). Simulations of 5 keV recoil events in Cu and Ni provide the following scenario of cascade collapse: atoms are ejected from the central region of the cascade by replacement collision sequences; the central region subsequently melts; vacancies are driven to the center of the cascade during resolidification where they may collapse into loops. Whether or not collapse occurs depends critically on the melting temperature of the metal and the energy density and total energy in the cascade. Results of TEM are presented in support of this mechanism. 14 refs., 4 figs., 1 tab

  2. Constructing a Watts-Strogatz network from a small-world network with symmetric degree distribution.

    Directory of Open Access Journals (Sweden)

    Mozart B C Menezes

    Full Text Available Though the small-world phenomenon is widespread in many real networks, it is still challenging to replicate a large network at the full scale for further study on its structure and dynamics when sufficient data are not readily available. We propose a method to construct a Watts-Strogatz network using a sample from a small-world network with symmetric degree distribution. Our method yields an estimated degree distribution which fits closely with that of a Watts-Strogatz network and leads into accurate estimates of network metrics such as clustering coefficient and degree of separation. We observe that the accuracy of our method increases as network size increases.

  3. Constructing a Watts-Strogatz network from a small-world network with symmetric degree distribution.

    Science.gov (United States)

    Menezes, Mozart B C; Kim, Seokjin; Huang, Rongbing

    2017-01-01

    Though the small-world phenomenon is widespread in many real networks, it is still challenging to replicate a large network at the full scale for further study on its structure and dynamics when sufficient data are not readily available. We propose a method to construct a Watts-Strogatz network using a sample from a small-world network with symmetric degree distribution. Our method yields an estimated degree distribution which fits closely with that of a Watts-Strogatz network and leads into accurate estimates of network metrics such as clustering coefficient and degree of separation. We observe that the accuracy of our method increases as network size increases.

  4. Analysis of static characteristic roots and propagation of disturbance of adjustable centrifuge cascade

    International Nuclear Information System (INIS)

    Li Weijie; Wu Zhongdi; Nong Guowei; Zeng Shi

    2014-01-01

    The hydraulic characteristic roots of a centrifuge cascade represent an important property of the cascade performance. Regulators and centrifuges are the key components that have a significant influence on the cascade hydraulic performance. The method used in diffusion cascades was adopted to obtain the static characteristic roots by solving the small disturbance equation for an adjustable centrifuge cascade in which all stages have the same fluid parameters. As the light stream flowrate of a centrifuge is irrelevant to the pressure at the outlet of the light flow, and the heavy stream flows at the speed of sound, there are only 2 static characteristic roots in the centrifuge cascade: the first root Z_1 is the main characteristic root and the second one Z_2 comes into play only when there exists a feed. The value of the main characteristic root is influenced by the amplification factor of the regulators, the fluid resistance in the main feed pipe and other factors. When Z_1 is smaller than 1, it increases with the fluid resistance. A large enough amplification factor has little impact on Z_1. The same distribution of the relative changes of the light fraction along the cascade is obtained by an analytical and a numerical method. (authors)

  5. Cascade of Refusal-What Does It Mean for the Future of Treatment as Prevention in Sub-Saharan Africa?

    Science.gov (United States)

    Katz, Ingrid T; Bangsberg, David R

    2016-04-01

    Recent recommendations by the World Health Organization support treatment for all people living with HIV (PLWH) globally to be initiated at the point of testing. While there has been marked success in efforts to identify and expand treatment for PLWH throughout sub-Saharan Africa, the goal of universal treatment may prove challenging to achieve. The pre-ART phase of the care cascade from HIV testing to HIV treatment initiation includes several social and structural barriers. One such barrier is antiretroviral therapy (ART) treatment refusal, a phenomenon in which HIV-infected individuals choose not to start treatment upon learning their ART eligibility. Our goal is to provide further understanding of why treatment-eligible adults may choose to present for HIV testing but not initiate ART when indicated. In this article, we will discuss factors driving pre-ART loss and present a framework for understanding the impact of decision-making on early losses in the care cascade, with a focus on ART refusal.

  6. Volcano geodesy in the Cascade arc, USA

    Science.gov (United States)

    Poland, Michael; Lisowski, Michael; Dzurisin, Daniel; Kramer, Rebecca; McLay, Megan; Pauk, Benjamin

    2017-01-01

    Experience during historical time throughout the Cascade arc and the lack of deep-seated deformation prior to the two most recent eruptions of Mount St. Helens might lead one to infer that Cascade volcanoes are generally quiescent and, specifically, show no signs of geodetic change until they are about to erupt. Several decades of geodetic data, however, tell a different story. Ground- and space-based deformation studies have identified surface displacements at five of the 13 major Cascade arc volcanoes that lie in the USA (Mount Baker, Mount St. Helens, South Sister, Medicine Lake, and Lassen volcanic center). No deformation has been detected at five volcanoes (Mount Rainier, Mount Hood, Newberry Volcano, Crater Lake, and Mount Shasta), and there are not sufficient data at the remaining three (Glacier Peak, Mount Adams, and Mount Jefferson) for a rigorous assessment. In addition, gravity change has been measured at two of the three locations where surveys have been repeated (Mount St. Helens and Mount Baker show changes, while South Sister does not). Broad deformation patterns associated with heavily forested and ice-clad Cascade volcanoes are generally characterized by low displacement rates, in the range of millimeters to a few centimeters per year, and are overprinted by larger tectonic motions of several centimeters per year. Continuous GPS is therefore the best means of tracking temporal changes in deformation of Cascade volcanoes and also for characterizing tectonic signals so that they may be distinguished from volcanic sources. Better spatial resolution of volcano deformation can be obtained through the use of campaign GPS, semipermanent GPS, and interferometric synthetic aperture radar observations, which leverage the accumulation of displacements over time to improve signal to noise. Deformation source mechanisms in the Cascades are diverse and include magma accumulation and withdrawal, post-emplacement cooling of recent volcanic deposits, magmatic

  7. Volcano geodesy in the Cascade arc, USA

    Science.gov (United States)

    Poland, Michael P.; Lisowski, Michael; Dzurisin, Daniel; Kramer, Rebecca; McLay, Megan; Pauk, Ben

    2017-08-01

    Experience during historical time throughout the Cascade arc and the lack of deep-seated deformation prior to the two most recent eruptions of Mount St. Helens might lead one to infer that Cascade volcanoes are generally quiescent and, specifically, show no signs of geodetic change until they are about to erupt. Several decades of geodetic data, however, tell a different story. Ground- and space-based deformation studies have identified surface displacements at five of the 13 major Cascade arc volcanoes that lie in the USA (Mount Baker, Mount St. Helens, South Sister, Medicine Lake, and Lassen volcanic center). No deformation has been detected at five volcanoes (Mount Rainier, Mount Hood, Newberry Volcano, Crater Lake, and Mount Shasta), and there are not sufficient data at the remaining three (Glacier Peak, Mount Adams, and Mount Jefferson) for a rigorous assessment. In addition, gravity change has been measured at two of the three locations where surveys have been repeated (Mount St. Helens and Mount Baker show changes, while South Sister does not). Broad deformation patterns associated with heavily forested and ice-clad Cascade volcanoes are generally characterized by low displacement rates, in the range of millimeters to a few centimeters per year, and are overprinted by larger tectonic motions of several centimeters per year. Continuous GPS is therefore the best means of tracking temporal changes in deformation of Cascade volcanoes and also for characterizing tectonic signals so that they may be distinguished from volcanic sources. Better spatial resolution of volcano deformation can be obtained through the use of campaign GPS, semipermanent GPS, and interferometric synthetic aperture radar observations, which leverage the accumulation of displacements over time to improve signal to noise. Deformation source mechanisms in the Cascades are diverse and include magma accumulation and withdrawal, post-emplacement cooling of recent volcanic deposits, magmatic

  8. A family of small-world network models built by complete graph and iteration-function

    Science.gov (United States)

    Ma, Fei; Yao, Bing

    2018-02-01

    Small-world networks are popular in real-life complex systems. In the past few decades, researchers presented amounts of small-world models, in which some are stochastic and the rest are deterministic. In comparison with random models, it is not only convenient but also interesting to study the topological properties of deterministic models in some fields, such as graph theory, theorem computer sciences and so on. As another concerned darling in current researches, community structure (modular topology) is referred to as an useful statistical parameter to uncover the operating functions of network. So, building and studying such models with community structure and small-world character will be a demanded task. Hence, in this article, we build a family of sparse network space N(t) which is different from those previous deterministic models. Even though, our models are established in the same way as them, iterative generation. By randomly connecting manner in each time step, every resulting member in N(t) has no absolutely self-similar feature widely shared in a large number of previous models. This makes our insight not into discussing a class certain model, but into investigating a group various ones spanning a network space. Somewhat surprisingly, our results prove all members of N(t) to possess some similar characters: (a) sparsity, (b) exponential-scale feature P(k) ∼α-k, and (c) small-world property. Here, we must stress a very screming, but intriguing, phenomenon that the difference of average path length (APL) between any two members in N(t) is quite small, which indicates this random connecting way among members has no great effect on APL. At the end of this article, as a new topological parameter correlated to reliability, synchronization capability and diffusion properties of networks, the number of spanning trees on a representative member NB(t) of N(t) is studied in detail, then an exact analytical solution for its spanning trees entropy is also

  9. Focus-based filtering + clustering technique for power-law networks with small world phenomenon

    Science.gov (United States)

    Boutin, François; Thièvre, Jérôme; Hascoët, Mountaz

    2006-01-01

    Realistic interaction networks usually present two main properties: a power-law degree distribution and a small world behavior. Few nodes are linked to many nodes and adjacent nodes are likely to share common neighbors. Moreover, graph structure usually presents a dense core that is difficult to explore with classical filtering and clustering techniques. In this paper, we propose a new filtering technique accounting for a user-focus. This technique extracts a tree-like graph with also power-law degree distribution and small world behavior. Resulting structure is easily drawn with classical force-directed drawing algorithms. It is also quickly clustered and displayed into a multi-level silhouette tree (MuSi-Tree) from any user-focus. We built a new graph filtering + clustering + drawing API and report a case study.

  10. A game-theoretic approach to optimize ad hoc networks inspired by small-world network topology

    Science.gov (United States)

    Tan, Mian; Yang, Tinghong; Chen, Xing; Yang, Gang; Zhu, Guoqing; Holme, Petter; Zhao, Jing

    2018-03-01

    Nodes in ad hoc networks are connected in a self-organized manner. Limited communication radius makes information transmit in multi-hop mode, and each forwarding needs to consume the energy of nodes. Insufficient communication radius or exhaustion of energy may cause the absence of some relay nodes and links, further breaking network connectivity. On the other hand, nodes in the network may refuse to cooperate due to objective faulty or personal selfish, hindering regular communication in the network. This paper proposes a model called Repeated Game in Small World Networks (RGSWN). In this model, we first construct ad hoc networks with small-world feature by forming "communication shortcuts" between multiple-radio nodes. Small characteristic path length reduces average forwarding times in networks; meanwhile high clustering coefficient enhances network robustness. Such networks still maintain relative low global power consumption, which is beneficial to extend the network survival time. Then we use MTTFT strategy (Mend-Tolerance Tit-for-Tat) for repeated game as a rule for the interactions between neighbors in the small-world networks. Compared with other five strategies of repeated game, this strategy not only punishes the nodes' selfishness more reasonably, but also has the best tolerance to the network failure. This work is insightful for designing an efficient and robust ad hoc network.

  11. How plasmas dissipate: cascade and the production of internal energy and entropy in weakly collisional plasma turbulence

    Science.gov (United States)

    Matthaeus, W. H.; Yang, Y.; Servidio, S.; Parashar, T.; Chasapis, A.; Roytershteyn, V.

    2017-12-01

    Turbulence cascade transfers energy from large scale to small scale but what happens once kinetic scales are reached? In a collisional medium, viscosity and resistivity remove fluctuation energy in favor of heat. In the weakly collisional solar wind, (or corona, m-sheath, etc.), the sequence of events must be different. Heating occurs, but through what mechanisms? In standard approaches, dissipation occurs though linear wave modes or instabilities and one seeks to identify them. A complementary view is that cascade leads to several channels of energy conversion, interchange and spatial rearrangement that collectively leads to production of internal energy. Channels may be described using compressible MHD & multispecies Vlasov Maxwell formulations. Key steps are: Conservative rearrangement of energy in space; Parallel incompressible and compressible cascades - conservative rearrangment in scale; electromagnetic work on particles that drives flows, both macroscopic and microscopic; and pressure-stress interactions, both compressive and shear-like, that produces internal energy. Examples given from MHD, PIC simulations and MMS observations. A more subtle issue is how entropy is related to this degeneration (or, "dissipation") of macroscopic, fluid-scale fluctuations. We discuss this in terms of Boltzmann and thermodynamic entropies, and velocity space effects of collisions.

  12. A small trip in the quantum world

    International Nuclear Information System (INIS)

    Klein, E.

    2004-01-01

    In 1905 a new physics was born: quantum mechanics that opened the way to the infinitely small made of atoms, particles and their interactions. For the first time in the history of sciences a discipline has required a thorough work of interpretation before being understood and applied. The author reviews the different interpretations and their inferences that have been postulated since the very beginning of quantum physics. Despite endless discussions about the true nature of quantum physics, this branch of physics remains an extraordinarily efficient tool to explain the world and has produced promising applications from laser to cryptography and to computers. The author describes all the challenges that have faced physicists concerning quantum physics among them: the wave-particle duality, the concept of reality, the significance of measuring or the collapse of the wave packet. (A.C.)

  13. Modeling of cascade and sub-cascade formation at high PKA energies in irradiated fusion structural materials

    International Nuclear Information System (INIS)

    Ryazanov, A.I.; Metelkin, E.V.; Semenov, E.V.

    2009-01-01

    A new theoretical model is developed for the investigations of cascade and sub-cascade formation in fusion structural materials under fast neutron irradiation at high primary knock-on atom energies. Light fusion structural materials: such as Be, C and SiC under 14 MeV neutron irradiation in fusion reactor will have the primary knock-on atoms with the energies up to 1 MeV. It is very difficult to use at such high energies the Monte-Carlo or molecular dynamic simulations [H.L. Heinisch, B.N. Singh, Philos. Mag. A67 (1993) 407; H.L. Heinisch, B.N. Singh, J. Nucl. Mater. 251 (1997) 77]. The developed model is based on the analytical consideration of elastic collisions between displaced moving atoms produced by primary knock-on atoms with some kinetic energies obtained from fast neutrons and crystal lattice atoms. The Thomas-Fermi interaction potential is used here for the description of these elastic atomic collisions. The suggested model takes into account also the electronic losses for moving atoms between elastic collisions. The self-consistent criterion for sub-cascade formation is suggested here which is based on the comparison of mean distance of primary knock-on atoms between consequent collisions of them with the target atoms and a size of sub-cascade produced by moving secondary knock-on atoms produced in such collisions. The analytical relations for the most important characteristics of cascades and sub-cascades are determined including the average number of sub-cascades per one primary knock-on atom in the dependence on its energy, the distance between sub-cascades and the average cascade and sub-cascade sizes. The developed model allows determining the total numbers, distribution functions of cascades and sub-cascades in dependence on their sizes and generation rate of cascades and sub-cascades for the different fusion neutron energy spectra. On the basis of this developed model the numerical calculations for main characteristics of cascades and sub-cascades

  14. Do stage-specific functional responses of consumers dampen the effects of subsidies on trophic cascades in streams?

    Science.gov (United States)

    Sato, Takuya; Watanabe, Katsutoshi

    2014-07-01

    Resource subsidies often weaken trophic cascades in recipient communities via consumers' functional response to the subsidies. Consumer populations are commonly stage-structured and may respond to the subsidies differently among the stages yet less is known about how this might impact the subsidy effects on the strength of trophic cascades in recipient systems. We show here, using a large-scale field experiment, that the stage structure of a recipient consumer would dampen the effects of terrestrial invertebrate subsidies on the strength of trophic cascade in streams. When a high input rate of the terrestrial invertebrates was available, both large and small fish stages switched their diet to the terrestrial subsidy, which weakened the trophic cascade in streams. However, when the input rate of the terrestrial invertebrates was at a moderate level, the terrestrial subsidy did not weaken the trophic cascade. This discrepancy was likely due to small fish stages being competitively excluded from feeding on the subsidy by larger stages of fish and primarily foraging on benthic invertebrates under the moderate input level. Although previous studies using single fish stages have clearly demonstrated that the terrestrial invertebrate input equivalent to our moderate input rate weakened the trophic cascade in streams, this subsidy effect might be overestimated given small fish stage may not switch their diet to the subsidy under competition with large fish stage. Given the ubiquity of consumer stage structure and interaction among consumer stages, the effects we saw might be widespread in nature, requiring future studies that explicitly involve consumer's stage structure into community ecology. © 2013 The Authors. Journal of Animal Ecology © 2013 British Ecological Society.

  15. Deuterium values from volcanic glass: A paleoelevation proxy for Oregon's Cascade Range

    Science.gov (United States)

    Carlson, T. B.; Bershaw, J. T.

    2016-12-01

    Hydrated volcanic glass has been used as a proxy to constrain Cenozoic paleoclimate across many of the world's mountain ranges. However, there are concerns that volcanic glass may not preserve the isotopic composition of syndepositional meteoric water. The Cascades are an excellent location to study the validity of hydrated volcanic glass as a paleoenvironmental proxy for several reasons. Moisture is derived from a single oceanic source and falls as orographic precipitation in the Cascades, leading to a characteristic altitude effect, or inverse relationship between elevation and the isotopic composition of meteoric water (δD). In addition, past studies have inferred uplift of the Cascades and an increase in the rain shadow effect since the Eocene through independent methods such as changing fossil assemblages, and other isotopic proxies including carbonates and fossil teeth. In this study, δD values of two hydrated tuff samples are compared: one prior to ( 29 Ma) and one following ( 5 Ma) the onset of High Cascade volcanism. The isotopic composition of these samples are interpreted in the context of modern water across the range to understand the potential of volcanic glass as a proxy for paleoelevation in the Pacific Northwest.

  16. [Analysis of the Characteristics of Infantile Small World Neural Network Node Properties Correlated with the Influencing Factors].

    Science.gov (United States)

    Qu, Haibo; Lu, Su; Zhang, Wenjing; Xiao, Yuan; Ning, Gang; Sun, Huaiqiang

    2016-10-01

    We applied resting-state functional magnetic resonance imaging(rfMRI)combined with graph theory to analyze 90 regions of the infantile small world neural network of the whole brain.We tried to get the following two points clear:1 whether the parameters of the node property of the infantile small world neural network are correlated with the level of infantile intelligence development;2 whether the parameters of the infantile small world neural network are correlated with the children’s baseline parameters,i.e.,the demographic parameters such as gender,age,parents’ education level,etc.Twelve cases of healthy infants were included in the investigation(9males and 3females with the average age of 33.42±8.42 months.)We then evaluated the level of infantile intelligence of all the cases and graded by Gesell Development Scale Test.We used a Siemens 3.0T Trio imaging system to perform resting-state(rs)EPI scans,and collected the BOLD functional Magnetic Resonance Imaging(fMRI)data.We performed the data processing with Statistical Parametric Mapping 5(SPM5)based on Matlab environment.Furthermore,we got the attributes of the whole brain small world and node attributes of 90 encephalic regions of templates of Anatomatic Automatic Labeling(ALL).At last,we carried out correlation study between the above-mentioned attitudes,intelligence scale parameters and demographic data.The results showed that many node attributes of small world neural network were closely correlated with intelligence scale parameters.Betweeness was mainly centered in thalamus,superior frontal gyrus,and occipital lobe(negative correlation).The r value of superior occipital gyrus associated with the individual and social intelligent scale was-0.729(P=0.007);degree was mainly centered in amygdaloid nucleus,superior frontal gyrus,and inferior parietal gyrus(positive correlation).The r value of inferior parietal gyrus associated with the gross motor intelligent scale was 0.725(P=0.008);efficiency was mainly

  17. Synchronization and Control of Halo-Chaos in Beam Transport Network with Small World Topology

    International Nuclear Information System (INIS)

    Liu Qiang; Fang Jinqing; Li Yong

    2007-01-01

    The synchronous conditions of two kinds of the small-world (SW) network are studied. The small world topology can affect on dynamical behaviors of the beam transport network (BTN) largely, if the BTN is constructed with the SW topology, the global linear coupling and special linear feedback can realize the synchronization control of beam halo-chaos as well as periodic state in the BTN with the SW topology, respectively. This important result can provide an effective way for the experimental study and the engineering design of the BTN in the high-current accelerator driven radioactive clean nuclear power systems, and may have potential use in prospective applications for halo-chaos secure communication.

  18. Effect of individual discharge cascades on the microstructure of plasma electrolytic oxidation coatings

    International Nuclear Information System (INIS)

    Troughton, S.C.; Nominé, A.; Dean, J.; Clyne, T.W.

    2016-01-01

    Highlights: • High speed current/video monitoring of discharge cascades. • SEM and X-ray Computed Tomography of cascade sites. • Effects of supply frequency and process interruption. • Explanation of cascade localisation. - Abstract: Short duration (∼1 s) PEO treatments have been applied to aluminium alloy samples on which coatings of thickness ∼100 μm had previously been created. This was done using the small area electrical monitoring system previously developed in the Gordon Laboratory in Cambridge. Voltage supply frequencies of 50 Hz and 2.5 kHz were employed. Fairly high resolution SEM micrographs were taken, covering the whole surface of small area samples (ie over a circular area of diameter about 0.9 mm). This was done both before and after the 1 s PEO treatments. X-ray tomographic data were also obtained in the vicinity of a recently-completed set of discharges. The outcomes of these observations were correlated with synchronised high speed electrical monitoring and video photography, carried out during the PEO treatment periods. Localised cascades (comprising hundreds of individual discharges) were observed in all cases, persisting throughout the 1 s periods and also reappearing in the same location when a second 1 s PEO treatment was applied to the same sample. This repetition of discharges at the same location is apparently due to the deep pores associated with these sites, creating a pathway of low electrical resistance, even after appreciable oxidation has occurred in the vicinity. Observations were made of the way in which the surfaces were reconstructed locally as discharge cascades occurred. With the high frequency voltage supply, discharge lifetimes were limited to the half-cycle period (of 200 μs), but in other respects the cascades were similar to those with the lower frequency. However, some discharges occurred during cathodic half-cycles with the high frequency supply, at the same location as the anodic discharges in the cascade

  19. Effect of individual discharge cascades on the microstructure of plasma electrolytic oxidation coatings

    Energy Technology Data Exchange (ETDEWEB)

    Troughton, S.C. [Department of Materials Science & Metallurgy, Cambridge Universitym 27 Charles Babbage Road, Cambridge CB3 0FS (United Kingdom); Nominé, A. [Department of Physical Sciences, Open University, Walton Hall, Milton Keynes MK7 6AA (United Kingdom); Dean, J. [Department of Materials Science & Metallurgy, Cambridge Universitym 27 Charles Babbage Road, Cambridge CB3 0FS (United Kingdom); Clyne, T.W., E-mail: twc10@cam.ac.uk [Department of Materials Science & Metallurgy, Cambridge Universitym 27 Charles Babbage Road, Cambridge CB3 0FS (United Kingdom)

    2016-12-15

    Highlights: • High speed current/video monitoring of discharge cascades. • SEM and X-ray Computed Tomography of cascade sites. • Effects of supply frequency and process interruption. • Explanation of cascade localisation. - Abstract: Short duration (∼1 s) PEO treatments have been applied to aluminium alloy samples on which coatings of thickness ∼100 μm had previously been created. This was done using the small area electrical monitoring system previously developed in the Gordon Laboratory in Cambridge. Voltage supply frequencies of 50 Hz and 2.5 kHz were employed. Fairly high resolution SEM micrographs were taken, covering the whole surface of small area samples (ie over a circular area of diameter about 0.9 mm). This was done both before and after the 1 s PEO treatments. X-ray tomographic data were also obtained in the vicinity of a recently-completed set of discharges. The outcomes of these observations were correlated with synchronised high speed electrical monitoring and video photography, carried out during the PEO treatment periods. Localised cascades (comprising hundreds of individual discharges) were observed in all cases, persisting throughout the 1 s periods and also reappearing in the same location when a second 1 s PEO treatment was applied to the same sample. This repetition of discharges at the same location is apparently due to the deep pores associated with these sites, creating a pathway of low electrical resistance, even after appreciable oxidation has occurred in the vicinity. Observations were made of the way in which the surfaces were reconstructed locally as discharge cascades occurred. With the high frequency voltage supply, discharge lifetimes were limited to the half-cycle period (of 200 μs), but in other respects the cascades were similar to those with the lower frequency. However, some discharges occurred during cathodic half-cycles with the high frequency supply, at the same location as the anodic discharges in the cascade

  20. Cascade annealing: an overview

    International Nuclear Information System (INIS)

    Doran, D.G.; Schiffgens, J.O.

    1976-04-01

    Concepts and an overview of radiation displacement damage modeling and annealing kinetics are presented. Short-term annealing methodology is described and results of annealing simulations performed on damage cascades generated using the Marlowe and Cascade programs are included. Observations concerning the inconsistencies and inadequacies of current methods are presented along with simulation of high energy cascades and simulation of longer-term annealing

  1. Suppression of anomalous synchronization and nonstationary behavior of neural network under small-world topology

    Science.gov (United States)

    Boaretto, B. R. R.; Budzinski, R. C.; Prado, T. L.; Kurths, J.; Lopes, S. R.

    2018-05-01

    It is known that neural networks under small-world topology can present anomalous synchronization and nonstationary behavior for weak coupling regimes. Here, we propose methods to suppress the anomalous synchronization and also to diminish the nonstationary behavior occurring in weakly coupled neural network under small-world topology. We consider a network of 2000 thermally sensitive identical neurons, based on the model of Hodgkin-Huxley in a small-world topology, with the probability of adding non local connection equal to p = 0 . 001. Based on experimental protocols to suppress anomalous synchronization, as well as nonstationary behavior of the neural network dynamics, we make use of (i) external stimulus (pulsed current); (ii) biologic parameters changing (neuron membrane conductance changes); and (iii) body temperature changes. Quantification analysis to evaluate phase synchronization makes use of the Kuramoto's order parameter, while recurrence quantification analysis, particularly the determinism, computed over the easily accessible mean field of network, the local field potential (LFP), is used to evaluate nonstationary states. We show that the methods proposed can control the anomalous synchronization and nonstationarity occurring for weak coupling parameter without any effect on the individual neuron dynamics, neither in the expected asymptotic synchronized states occurring for large values of the coupling parameter.

  2. Small molecule screening identifies targetable zebrafish pigmentation pathways

    DEFF Research Database (Denmark)

    Colanesi, Sarah; Taylor, Kerrie L; Temperley, Nicholas D

    2012-01-01

    Small molecules complement genetic mutants and can be used to probe pigment cell biology by inhibiting specific proteins or pathways. Here, we present the results of a screen of active compounds for those that affect the processes of melanocyte and iridophore development in zebrafish and investig......Small molecules complement genetic mutants and can be used to probe pigment cell biology by inhibiting specific proteins or pathways. Here, we present the results of a screen of active compounds for those that affect the processes of melanocyte and iridophore development in zebrafish...... and investigate the effects of a few of these compounds in further detail. We identified and confirmed 57 compounds that altered pigment cell patterning, number, survival, or differentiation. Additional tissue targets and toxicity of small molecules are also discussed. Given that the majority of cell types...

  3. An evolutionary cascade model for sauropod dinosaur gigantism--overview, update and tests.

    Directory of Open Access Journals (Sweden)

    P Martin Sander

    Full Text Available Sauropod dinosaurs are a group of herbivorous dinosaurs which exceeded all other terrestrial vertebrates in mean and maximal body size. Sauropod dinosaurs were also the most successful and long-lived herbivorous tetrapod clade, but no abiological factors such as global environmental parameters conducive to their gigantism can be identified. These facts justify major efforts by evolutionary biologists and paleontologists to understand sauropods as living animals and to explain their evolutionary success and uniquely gigantic body size. Contributions to this research program have come from many fields and can be synthesized into a biological evolutionary cascade model of sauropod dinosaur gigantism (sauropod gigantism ECM. This review focuses on the sauropod gigantism ECM, providing an updated version based on the contributions to the PLoS ONE sauropod gigantism collection and on other very recent published evidence. The model consist of five separate evolutionary cascades ("Reproduction", "Feeding", "Head and neck", "Avian-style lung", and "Metabolism". Each cascade starts with observed or inferred basal traits that either may be plesiomorphic or derived at the level of Sauropoda. Each trait confers hypothetical selective advantages which permit the evolution of the next trait. Feedback loops in the ECM consist of selective advantages originating from traits higher in the cascades but affecting lower traits. All cascades end in the trait "Very high body mass". Each cascade is linked to at least one other cascade. Important plesiomorphic traits of sauropod dinosaurs that entered the model were ovipary as well as no mastication of food. Important evolutionary innovations (derived traits were an avian-style respiratory system and an elevated basal metabolic rate. Comparison with other tetrapod lineages identifies factors limiting body size.

  4. An evolutionary cascade model for sauropod dinosaur gigantism--overview, update and tests.

    Science.gov (United States)

    Sander, P Martin

    2013-01-01

    Sauropod dinosaurs are a group of herbivorous dinosaurs which exceeded all other terrestrial vertebrates in mean and maximal body size. Sauropod dinosaurs were also the most successful and long-lived herbivorous tetrapod clade, but no abiological factors such as global environmental parameters conducive to their gigantism can be identified. These facts justify major efforts by evolutionary biologists and paleontologists to understand sauropods as living animals and to explain their evolutionary success and uniquely gigantic body size. Contributions to this research program have come from many fields and can be synthesized into a biological evolutionary cascade model of sauropod dinosaur gigantism (sauropod gigantism ECM). This review focuses on the sauropod gigantism ECM, providing an updated version based on the contributions to the PLoS ONE sauropod gigantism collection and on other very recent published evidence. The model consist of five separate evolutionary cascades ("Reproduction", "Feeding", "Head and neck", "Avian-style lung", and "Metabolism"). Each cascade starts with observed or inferred basal traits that either may be plesiomorphic or derived at the level of Sauropoda. Each trait confers hypothetical selective advantages which permit the evolution of the next trait. Feedback loops in the ECM consist of selective advantages originating from traits higher in the cascades but affecting lower traits. All cascades end in the trait "Very high body mass". Each cascade is linked to at least one other cascade. Important plesiomorphic traits of sauropod dinosaurs that entered the model were ovipary as well as no mastication of food. Important evolutionary innovations (derived traits) were an avian-style respiratory system and an elevated basal metabolic rate. Comparison with other tetrapod lineages identifies factors limiting body size.

  5. A small world of weak ties provides optimal global integration of self-similar modules in functional brain networks.

    Science.gov (United States)

    Gallos, Lazaros K; Makse, Hernán A; Sigman, Mariano

    2012-02-21

    The human brain is organized in functional modules. Such an organization presents a basic conundrum: Modules ought to be sufficiently independent to guarantee functional specialization and sufficiently connected to bind multiple processors for efficient information transfer. It is commonly accepted that small-world architecture of short paths and large local clustering may solve this problem. However, there is intrinsic tension between shortcuts generating small worlds and the persistence of modularity, a global property unrelated to local clustering. Here, we present a possible solution to this puzzle. We first show that a modified percolation theory can define a set of hierarchically organized modules made of strong links in functional brain networks. These modules are "large-world" self-similar structures and, therefore, are far from being small-world. However, incorporating weaker ties to the network converts it into a small world preserving an underlying backbone of well-defined modules. Remarkably, weak ties are precisely organized as predicted by theory maximizing information transfer with minimal wiring cost. This trade-off architecture is reminiscent of the "strength of weak ties" crucial concept of social networks. Such a design suggests a natural solution to the paradox of efficient information flow in the highly modular structure of the brain.

  6. Dynamic behavior of the interaction between epidemics and cascades on heterogeneous networks

    Science.gov (United States)

    Jiang, Lurong; Jin, Xinyu; Xia, Yongxiang; Ouyang, Bo; Wu, Duanpo

    2014-12-01

    Epidemic spreading and cascading failure are two important dynamical processes on complex networks. They have been investigated separately for a long time. But in the real world, these two dynamics sometimes may interact with each other. In this paper, we explore a model combined with the SIR epidemic spreading model and a local load sharing cascading failure model. There exists a critical value of the tolerance parameter for which the epidemic with high infection probability can spread out and infect a fraction of the network in this model. When the tolerance parameter is smaller than the critical value, the cascading failure cuts off the abundance of paths and blocks the spreading of the epidemic locally. While the tolerance parameter is larger than the critical value, the epidemic spreads out and infects a fraction of the network. A method for estimating the critical value is proposed. In simulations, we verify the effectiveness of this method in the uncorrelated configuration model (UCM) scale-free networks.

  7. Integrated Broadband Quantum Cascade Laser

    Science.gov (United States)

    Mansour, Kamjou (Inventor); Soibel, Alexander (Inventor)

    2016-01-01

    A broadband, integrated quantum cascade laser is disclosed, comprising ridge waveguide quantum cascade lasers formed by applying standard semiconductor process techniques to a monolithic structure of alternating layers of claddings and active region layers. The resulting ridge waveguide quantum cascade lasers may be individually controlled by independent voltage potentials, resulting in control of the overall spectrum of the integrated quantum cascade laser source. Other embodiments are described and claimed.

  8. Molecular dynamics studies on the structural effects of displacement cascades in UO2 matrix

    International Nuclear Information System (INIS)

    Brutzel, L. Van; Rarivomanantsoa, M.; Ghaleb, D.

    2004-01-01

    A set of molecular dynamics simulations have been carried out in order to study, at the atomic scale, the ballistic damages undergo by the UO 2 matrix. The morphologies of the displacement cascades simulations initiated by an uranium atoms with a Primary Knout on Atom (PKA) energy ranges from 1 keV to 20 keV are analysed. In agreement with all the experimental results no amorphization has been found even at small scales. For the cascade initiated with a PKA energy of 20 keV several sub-cascade branches appear in many directions from the cascade core. It seems that these sub-cascades arise from a quasi channeling of uranium atoms in specific direction over long distances. However, in average the atoms are displaced no more than 2 to 3 crystallographic sites. The evolution of the Frenkel pairs with the initial energy of the PKA exhibits a power law behavior with an exponent close to 0.9 showing a discrepancy with the linear NRT law. No significant clustering of local defects such as vacancies and interstitials have been found, nevertheless vacancies are preferentially created near the core of the cascade whereas the atoms in interstitial positions are mainly located at the periphery of the sub-cascade branches. (authors)

  9. Cognition Is Related to Resting-State Small-World Network Topology: An Magnetoencephalographic Study

    NARCIS (Netherlands)

    Douw, L.; Schoonheim, M.M.; Landi, D.; van der Meer, M.L.; Geurts, J.J.G.; Reijneveld, J.C.; Klein, M.; Stam, C.J.

    2011-01-01

    Brain networks and cognition have recently begun to attract attention: studies suggest that more efficiently wired resting-state brain networks are indeed correlated with better cognitive performance. "Small-world" brain networks combine local segregation with global integration, hereby subserving

  10. Synchronization of the small-world neuronal network with unreliable synapses

    International Nuclear Information System (INIS)

    Li, Chunguang; Zheng, Qunxian

    2010-01-01

    As is well known, synchronization phenomena are ubiquitous in neuronal systems. Recently a lot of work concerning the synchronization of the neuronal network has been accomplished. In these works, the synapses are usually considered reliable, but experimental results show that, in biological neuronal networks, synapses are usually unreliable. In our previous work, we have studied the synchronization of the neuronal network with unreliable synapses; however, we have not paid attention to the effect of topology on the synchronization of the neuronal network. Several recent studies have found that biological neuronal networks have typical properties of small-world networks, characterized by a short path length and high clustering coefficient. In this work, mainly based on the small-world neuronal network (SWNN) with inhibitory neurons, we study the effect of network topology on the synchronization of the neuronal network with unreliable synapses. Together with the network topology, the effects of the GABAergic reversal potential, time delay and noise are also considered. Interestingly, we found a counter-intuitive phenomenon for the SWNN with specific shortcut adding probability, that is, the less reliable the synapses, the better the synchronization performance of the SWNN. We also consider the effects of both local noise and global noise in this work. It is shown that these two different types of noise have distinct effects on the synchronization: one is negative and the other is positive

  11. Aspects of microstructure evolution under cascade damage conditions

    International Nuclear Information System (INIS)

    Singh, B.N.; Trinkaus, H.; Barashev, A.V.

    1997-01-01

    The conventional theoretical models describing the damage accumulation, particularly void swelling, under cascade damage conditions do not include treatments of important features such as intracascade clustering of self-interstitial atoms (SIAs) and one-dimensional glide of SIA clusters produced in the cascades. Recently, it has been suggested that the problem can be treated in terms of 'production bias' and one-dimensional glide of small SIA clusters. In the earlier treatments a 'mean size approximation' was used for the defect clusters and cavities evolving during irradiation. In the present work, we use the 'size distribution function' to determine the dose dependence of sink strengths, vacancy supersaturation and void swelling as a function of dislocation density and grain size within the framework of production bias model and glide of small SIA clusters. In this work, the role of the sessile-glissile loop transformation (due to vacancy supersaturation) on the damage accumulation behaviour is included. The calculated results on void swelling are compared with the experimental results as well as the results of the earlier calculations using the 'mean size approximation'. The calculated results agree very well with the experimental results. (orig.)

  12. Conjugation of cascades

    International Nuclear Information System (INIS)

    San Martin, Jesus; Rodriguez-Perez, Daniel

    2009-01-01

    Presented in this work are some results relative to sequences found in the logistic equation bifurcation diagram, which is the unimodal quadratic map prototype. All of the different saddle-node bifurcation cascades, associated with every last appearance p-periodic orbit (p=3,4,5,...), can also be generated from the very Feigenbaum cascade. In this way it is evidenced the relationship between both cascades. The orbits of every saddle-node bifurcation cascade, mentioned above, are located in different chaotic bands, and this determines a sequence of orbits converging to every band-merging Misiurewicz point. In turn, these accumulation points form a sequence whose accumulation point is the Myrberg-Feigenbaum point. It is also proven that the first appearance orbits in the n-chaotic band converge to the same point as the last appearance orbits of the (n + 1)-chaotic band. The symbolic sequences of band-merging Misiurewicz points are computed for any window.

  13. Magnetic Helicity Conservation and Inverse Energy Cascade in Electron Magnetohydrodynamic Wave Packets

    International Nuclear Information System (INIS)

    Cho, Jungyeon

    2011-01-01

    Electron magnetohydrodynamics (EMHD) provides a fluidlike description of small-scale magnetized plasmas. An EMHD wave propagates along magnetic field lines. The direction of propagation can be either parallel or antiparallel to the magnetic field lines. We numerically study propagation of three-dimensional (3D) EMHD wave packets moving in one direction. We obtain two major results. (1) Unlike its magnetohydrodynamic (MHD) counterpart, an EMHD wave packet is dispersive. Because of this, EMHD wave packets traveling in one direction create opposite-traveling wave packets via self-interaction and cascade energy to smaller scales. (2) EMHD wave packets traveling in one direction clearly exhibit inverse energy cascade. We find that the latter is due to conservation of magnetic helicity. We compare inverse energy cascade in 3D EMHD turbulence and two-dimensional (2D) hydrodynamic turbulence.

  14. Magnetic helicity conservation and inverse energy cascade in electron magnetohydrodynamic wave packets.

    Science.gov (United States)

    Cho, Jungyeon

    2011-05-13

    Electron magnetohydrodynamics (EMHD) provides a fluidlike description of small-scale magnetized plasmas. An EMHD wave propagates along magnetic field lines. The direction of propagation can be either parallel or antiparallel to the magnetic field lines. We numerically study propagation of three-dimensional (3D) EMHD wave packets moving in one direction. We obtain two major results. (1) Unlike its magnetohydrodynamic (MHD) counterpart, an EMHD wave packet is dispersive. Because of this, EMHD wave packets traveling in one direction create opposite-traveling wave packets via self-interaction and cascade energy to smaller scales. (2) EMHD wave packets traveling in one direction clearly exhibit inverse energy cascade. We find that the latter is due to conservation of magnetic helicity. We compare inverse energy cascade in 3D EMHD turbulence and two-dimensional (2D) hydrodynamic turbulence.

  15. Critical assessment and ramifications of a purported marine trophic cascade

    Science.gov (United States)

    Grubbs, R. Dean; Carlson, John K; Romine, Jason G.; Curtis, Tobey H; McElroy, W. David; McCandless, Camilla T; Cotton, Charles F; Musick, John A.

    2016-01-01

    When identifying potential trophic cascades, it is important to clearly establish the trophic linkages between predators and prey with respect to temporal abundance, demographics, distribution, and diet. In the northwest Atlantic Ocean, the depletion of large coastal sharks was thought to trigger a trophic cascade whereby predation release resulted in increased cownose ray abundance, which then caused increased predation on and subsequent collapse of commercial bivalve stocks. These claims were used to justify the development of a predator-control fishery for cownose rays, the “Save the Bay, Eat a Ray” fishery, to reduce predation on commercial bivalves. A reexamination of data suggests declines in large coastal sharks did not coincide with purported rapid increases in cownose ray abundance. Likewise, the increase in cownose ray abundance did not coincide with declines in commercial bivalves. The lack of temporal correlations coupled with published diet data suggest the purported trophic cascade is lacking the empirical linkages required of a trophic cascade. Furthermore, the life history parameters of cownose rays suggest they have low reproductive potential and their populations are incapable of rapid increases. Hypothesized trophic cascades should be closely scrutinized as spurious conclusions may negatively influence conservation and management decisions.

  16. Robustness of cluster synchronous patterns in small-world networks with inter-cluster co-competition balance

    International Nuclear Information System (INIS)

    Zhang, Jianbao; Ma, Zhongjun; Chen, Guanrong

    2014-01-01

    All edges in the classical Watts and Strogatz's small-world network model are unweighted and cooperative (positive). By introducing competitive (negative) inter-cluster edges and assigning edge weights to mimic more realistic networks, this paper develops a modified model which possesses co-competitive weighted couplings and cluster structures while maintaining the common small-world network properties of small average shortest path lengths and large clustering coefficients. Based on theoretical analysis, it is proved that the new model with inter-cluster co-competition balance has an important dynamical property of robust cluster synchronous pattern formation. More precisely, clusters will neither merge nor split regardless of adding or deleting nodes and edges, under the condition of inter-cluster co-competition balance. Numerical simulations demonstrate the robustness of the model against the increase of the coupling strength and several topological variations

  17. Robustness of cluster synchronous patterns in small-world networks with inter-cluster co-competition balance

    Science.gov (United States)

    Zhang, Jianbao; Ma, Zhongjun; Chen, Guanrong

    2014-06-01

    All edges in the classical Watts and Strogatz's small-world network model are unweighted and cooperative (positive). By introducing competitive (negative) inter-cluster edges and assigning edge weights to mimic more realistic networks, this paper develops a modified model which possesses co-competitive weighted couplings and cluster structures while maintaining the common small-world network properties of small average shortest path lengths and large clustering coefficients. Based on theoretical analysis, it is proved that the new model with inter-cluster co-competition balance has an important dynamical property of robust cluster synchronous pattern formation. More precisely, clusters will neither merge nor split regardless of adding or deleting nodes and edges, under the condition of inter-cluster co-competition balance. Numerical simulations demonstrate the robustness of the model against the increase of the coupling strength and several topological variations.

  18. Robustness of cluster synchronous patterns in small-world networks with inter-cluster co-competition balance

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Jianbao [School of Science, Hangzhou Dianzi University, Hangzhou 310018 (China); Ma, Zhongjun, E-mail: mzj1234402@163.com [School of Mathematics and Computing Science, Guilin University of Electronic Technology, Guilin 541004 (China); Chen, Guanrong [Department of Electronic Engineering, City University of Hong Kong, Kowloon, Hong Kong (China)

    2014-06-15

    All edges in the classical Watts and Strogatz's small-world network model are unweighted and cooperative (positive). By introducing competitive (negative) inter-cluster edges and assigning edge weights to mimic more realistic networks, this paper develops a modified model which possesses co-competitive weighted couplings and cluster structures while maintaining the common small-world network properties of small average shortest path lengths and large clustering coefficients. Based on theoretical analysis, it is proved that the new model with inter-cluster co-competition balance has an important dynamical property of robust cluster synchronous pattern formation. More precisely, clusters will neither merge nor split regardless of adding or deleting nodes and edges, under the condition of inter-cluster co-competition balance. Numerical simulations demonstrate the robustness of the model against the increase of the coupling strength and several topological variations.

  19. Familial Hypercholesterolemia: Cascade Screening in Children and Relatives of the Affected.

    Science.gov (United States)

    Setia, Nitika; Saxena, Renu; Sawhney, J P S; Verma, Ishwar C

    2018-05-01

    Familial Hypercholesterolemia (FH) is an inherited disorder of lipid metabolism characterized by very high low density lipoprotein (LDL) cholesterol since birth, resulting in premature atherosclerosis and coronary artery disease (CAD). Cascade screening of children and family members of proven FH individuals can identify more subjects who have high LDL cholesterol or the family mutation and appropriate intervention can reduce their risk of atherosclerosis and prevent its complications. Cascade screening by molecular testing, was carried out in 133 family members, comprising 24 children, of 31 probands with FH having a pathogenic mutation in LDLR/ApoB gene. Lipid profiles were obtained in 44 family members including 11 children. Of 133 family members tested, 88 (66.1%) were identified to carry the family mutation. Twelve of these were children below 18 y of age and 76 were adults. CAD was present in 15 (11.2%) family members and 63(47.4%) family members, including nine children, were already on Lipid Lowering Therapy. Cascade screening led to identification of 88 new cases, with a pathogenic mutation, who were at a very high risk of developing premature CAD. The authors identified 12 children with family specific mutation, out of which 9 were initiated on low dose statin therapy. Four homozygous children were treated with high dose statins because of substantially increased risk of CAD. Cascade screening, therefore, proved to be a successful initiative towards primary prevention of CAD in India.

  20. Critical behavior of the XY-rotor model on regular and small-world networks

    Science.gov (United States)

    De Nigris, Sarah; Leoncini, Xavier

    2013-07-01

    We study the XY rotors model on small networks whose number of links scales with the system size Nlinks˜Nγ, where 1≤γ≤2. We first focus on regular one-dimensional rings in the microcanonical ensemble. For γ1.5, the system equilibrium properties are found to be identical to the mean field, which displays a second-order phase transition at a critical energy density ɛ=E/N,ɛc=0.75. Moreover, for γc≃1.5 we find that a nontrivial state emerges, characterized by an infinite susceptibility. We then consider small-world networks, using the Watts-Strogatz mechanism on the regular networks parametrized by γ. We first analyze the topology and find that the small-world regime appears for rewiring probabilities which scale as pSW∝1/Nγ. Then considering the XY-rotors model on these networks, we find that a second-order phase transition occurs at a critical energy ɛc which logarithmically depends on the topological parameters p and γ. We also define a critical probability pMF, corresponding to the probability beyond which the mean field is quantitatively recovered, and we analyze its dependence on γ.

  1. An Evolutionary Cascade Model for Sauropod Dinosaur Gigantism - Overview, Update and Tests

    Science.gov (United States)

    Sander, P. Martin

    2013-01-01

    Sauropod dinosaurs are a group of herbivorous dinosaurs which exceeded all other terrestrial vertebrates in mean and maximal body size. Sauropod dinosaurs were also the most successful and long-lived herbivorous tetrapod clade, but no abiological factors such as global environmental parameters conducive to their gigantism can be identified. These facts justify major efforts by evolutionary biologists and paleontologists to understand sauropods as living animals and to explain their evolutionary success and uniquely gigantic body size. Contributions to this research program have come from many fields and can be synthesized into a biological evolutionary cascade model of sauropod dinosaur gigantism (sauropod gigantism ECM). This review focuses on the sauropod gigantism ECM, providing an updated version based on the contributions to the PLoS ONE sauropod gigantism collection and on other very recent published evidence. The model consist of five separate evolutionary cascades (“Reproduction”, “Feeding”, “Head and neck”, “Avian-style lung”, and “Metabolism”). Each cascade starts with observed or inferred basal traits that either may be plesiomorphic or derived at the level of Sauropoda. Each trait confers hypothetical selective advantages which permit the evolution of the next trait. Feedback loops in the ECM consist of selective advantages originating from traits higher in the cascades but affecting lower traits. All cascades end in the trait “Very high body mass”. Each cascade is linked to at least one other cascade. Important plesiomorphic traits of sauropod dinosaurs that entered the model were ovipary as well as no mastication of food. Important evolutionary innovations (derived traits) were an avian-style respiratory system and an elevated basal metabolic rate. Comparison with other tetrapod lineages identifies factors limiting body size. PMID:24205267

  2. Cascade of circulations in fluid turbulence.

    Science.gov (United States)

    Eyink, Gregory L

    2006-12-01

    Kelvin's theorem on conservation of circulations is an essential ingredient of Taylor's theory of turbulent energy dissipation by the process of vortex-line stretching. In previous work, we have proposed a nonlinear mechanism for the breakdown of Kelvin's theorem in ideal turbulence at infinite Reynolds number. We develop here a detailed physical theory of this cascade of circulations. Our analysis is based upon an effective equation for large-scale coarse-grained velocity, which contains a turbulent-induced vortex force that can violate Kelvin's theorem. We show that singularities of sufficient strength, which are observed to exist in turbulent flow, can lead to nonvanishing dissipation of circulation for an arbitrarily small coarse-graining length in the effective equations. This result is an analog for circulation of Onsager's theorem on energy dissipation for singular Euler solutions. The physical mechanism of the breakdown of Kelvin's theorem is diffusion of lines of large-scale vorticity out of the advected loop. This phenomenon can be viewed as a classical analog of the Josephson-Anderson phase-slip phenomenon in superfluids due to quantized vortex lines. We show that the circulation cascade is local in scale and use this locality to develop concrete expressions for the turbulent vortex force by a multiscale gradient expansion. We discuss implications for Taylor's theory of turbulent dissipation and we point out some related cascade phenomena, in particular for magnetic flux in magnetohydrodynamic turbulence.

  3. Pair Cascades and Deathlines in Magnetic Fields with Offset Polar Caps

    Science.gov (United States)

    Harding, Alice K.; Muslimov, Alex G.

    2012-01-01

    We present results of electron-positron pair cascade simulations in a dipole magnetic field whose polar cap is offset from the dipole axis. In such a field geometry, the polar cap is displaced a small fraction of the neutron star radius from the star symmetry axis and the field line radius of curvature is modified. Using the modified parallel electric field near the offset polar cap, we simulate pair cascades to determine the pair deathlines and pair multiplicities as a function of the offset. We find that the pair multiplicity can change dr;unatically with a modest offset, with a significant increase on one side of the polar cap. Lower pair deathlines allow a larger fraction of the pulsar population, that include old and millisecond pulsars, to produce cascades with high multiplicity. The results have some important implications for pulsar particle production, high-energy emission and cosmic-ray contribution.

  4. Seroprevalence and characterization of pestivirus infections in small ruminants and new world camelids in Switzerland.

    Science.gov (United States)

    Danuser, R; Vogt, H-R; Kaufmann, Th; Peterhans, E; Zanoni, R

    2009-03-01

    The seroprevalence of pestivirus infections in small ruminants and new world camelids in Switzerland was determined. In 5'059 sera of sheep from 382 herds, 503 sera of goats from 54 herds and 109 sera of alpacas and lamas from 53 herds, population prevalences of 16.1% (sheep), 25.4% (goats) and 4.6% (new world camelids), respectively, were found. In order to determine the source of infection, the serological reactions were further characterized by cross-neutralization against two pestiviruses representing the genotypes BVDV (Bovine Virus Diarrhea Virus)-1 and BDV (Border Disease Virus)-1. Based on the ratio of respective antibody titres, 56.1% of the infections in sheep were induced by a BDV-1, 12.9% by a BVDV-1 and 31.0% by an unresolved pestivirus. In goats, the corresponding proportions were 23.4%, 10.2% and 66.4%, respectively. In Alpacas and Lamas, the source of infection of 1 animal was BDV-1 and that of 4 seropositive animals remained unresolved. In view of the phylogenetic relationship between pestiviruses, the unresolved source of infection is most probably attributable to other pestivirus genotypes circulating in small ruminants and new world camelids. Due to the predominance of pestiviral genotypes other than BVDV-1, the risk of transmission of BVDV from persistently infected small ruminants and new world camelids to cattle appears to be moderate, apart from close direct contact in mixed animal husbandry, communal pasturing and grazing in the Alps.

  5. Limits of Risk Predictability in a Cascading Alternating Renewal Process Model.

    Science.gov (United States)

    Lin, Xin; Moussawi, Alaa; Korniss, Gyorgy; Bakdash, Jonathan Z; Szymanski, Boleslaw K

    2017-07-27

    Most risk analysis models systematically underestimate the probability and impact of catastrophic events (e.g., economic crises, natural disasters, and terrorism) by not taking into account interconnectivity and interdependence of risks. To address this weakness, we propose the Cascading Alternating Renewal Process (CARP) to forecast interconnected global risks. However, assessments of the model's prediction precision are limited by lack of sufficient ground truth data. Here, we establish prediction precision as a function of input data size by using alternative long ground truth data generated by simulations of the CARP model with known parameters. We illustrate the approach on a model of fires in artificial cities assembled from basic city blocks with diverse housing. The results confirm that parameter recovery variance exhibits power law decay as a function of the length of available ground truth data. Using CARP, we also demonstrate estimation using a disparate dataset that also has dependencies: real-world prediction precision for the global risk model based on the World Economic Forum Global Risk Report. We conclude that the CARP model is an efficient method for predicting catastrophic cascading events with potential applications to emerging local and global interconnected risks.

  6. Placement of Synchronized Measurements for Power System Observability during Cascaded Outages

    Science.gov (United States)

    Thirugnanasambandam, Venkatesh; Jain, Trapti

    2017-11-01

    Cascaded outages often result in power system islanding followed by a blackout and therefore considered as a severe disturbance. Maintaining the observability of each island may help in taking proper control actions to preserve the stability of individual islands thus, averting system collapse. With this intent, a strategy for placement of synchronized measurements, which can be obtained from phasor measurement units (PMU), has been proposed in this paper to keep the system observable during cascaded outages also. Since, all the cascaded failures may not lead to islanding situations, therefore, failures leading to islanding as well as non-islanding situations have been considered. A topology based algorithm has been developed to identify the islanding/non-islanding condition created by a particular cascaded event. Additional contingencies such as single line loss and single PMU failure have also been considered after the occurrence of cascaded events. The proposed method is further extended to incorporate the measurement redundancy, which is desirable for a reliable state estimation. The proposed scheme is tested on IEEE 14-bus, IEEE 30-bus and a practical Indian 246-bus networks. The numerical results ensure the observability of the power system under system intact as well as during cascaded islanding and non-islanding disturbances.

  7. Bifenthrin causes trophic cascades and alters insect emergence in mesocosms: implication for small streams

    Science.gov (United States)

    Rogers, Holly; Schmidt, Travis S.; Dabney, Brittanie L.; Hladik, Michelle; Mahler, Barbara J.; Van Metre, Peter C.

    2016-01-01

    Direct and indirect ecological effects of the widely used insecticide bifenthrin on stream ecosystems are largely unknown. To investigate such effects, a manipulative experiment was conducted in stream mesocosms that were colonized by aquatic insect communities and exposed to bifenthrin-contaminated sediment; implications for natural streams were interpreted through comparison of mesocosm results to a survey of 100 Midwestern streams, USA. In the mesocosm experiment, direct effects of bifenthrin exposure included reduced larval macroinvertebrate abundance, richness, and biomass at concentrations (EC50s ranged 197.6 – 233.5 ng bifenthrin/ g organic carbon) previously thought safe for aquatic life. Indirect effects included a trophic cascade in which periphyton abundance increased after macroinvertebrate scrapers decreased. Adult emergence dynamics and corresponding terrestrial subsidies were altered at all bifenthrin concentrations tested. Extrapolating these results to the Midwestern stream assessment suggests pervasive ecological effects, with altered emergence dynamics likely in 40% of streams and a trophic cascade in 7% of streams. This study provides new evidence that a common pyrethroid might alter aquatic and terrestrial ecosystem function at the regional scale.

  8. Effect of separation factors on product assay of an ideal cascade composed of UF6 centrifuges

    International Nuclear Information System (INIS)

    Yamashita, S.; Okamoto, T.

    1975-01-01

    Kinetics equations using two assumptions describe an ideal cascade with accuracy. Using the kinetics equations, it is found that if the decrease of the separation factor in a selected stage is small, the product can be withdrawn at the product assay allowed for shipment without stopping the operation of the ideal cascade composed of the model centrifuges (approximately 4 kg SWU/yr, α = 1.135). Moreover, the fraction of centrifuges permissible to stop in case of an accident is found to be 4 to 5 percent of the model centrifuges in each stage in the enriching section of the ideal cascade. (U.S.)

  9. Cascade reactor: introduction

    International Nuclear Information System (INIS)

    Pitts, J.H.

    1985-01-01

    Cascade is a concept for an ultrasafe, highly efficient, easily built reactor to convert inertial-confinement fusion energy into electrical power. The Cascade design includes a rotating double-cone-shaped chamber in which a moving, 1-m-thick ceramic granular blanket is held against the reactor wall by centrifugal action. The granular material absorbs energy from the fusion reactions. Accomplishments this year associated with Cascade included improvements to simplify chamber design and lower activation. The authors switched from a steel chamber wall to one made from silicon-carbide (SiC) panels held in compression by SiC-fiber/Al-composite tendons that gird the chamber both circumferentially and axially. The authors studies a number of heat-exchanger designs and selected a gravity-flow cascade design with a vacuum on the primary side. This design allows granules leaving the chamber to be transported to the heat exchangers using their own peripheral speed. The granules transfer their thermal energy and return to the chamber gravitationally: no vacuum locks or conveyors are needed

  10. Small-worldness characteristics and its gender relation in specific hemispheric networks.

    Science.gov (United States)

    Miraglia, F; Vecchio, F; Bramanti, P; Rossini, P M

    2015-12-03

    Aim of this study was to verify whether the topological organization of human brain functional networks is different for males and females in resting state EEGs. Undirected and weighted brain networks were computed by eLORETA lagged linear connectivity in 130 subjects (59 males and 71 females) within each hemisphere and in four resting state networks (Attentional Network (AN), Frontal Network (FN), Sensorimotor Network (SN), Default Mode Network (DMN)). We found that small-world (SW) architecture in the left hemisphere Frontal network presented differences in both delta and alpha band, in particular lower values in delta and higher in alpha 2 in males respect to females while in the right hemisphere differences were found in lower values of SW in males respect to females in gamma Attentional, delta Sensorimotor and delta and gamma DMNs. Gender small-worldness differences in some of resting state networks indicated that there are specific brain differences in the EEG rhythms when the brain is in the resting-state condition. These specific regions could be considered related to the functions of behavior and cognition and should be taken into account both for research on healthy and brain diseased subjects. Copyright © 2015 IBRO. Published by Elsevier Ltd. All rights reserved.

  11. Avoiding the "It's a Small World" Effect: A Lesson Plan to Explore Diversity

    Science.gov (United States)

    Endacott, Jason L.; Bowles, Freddie A.

    2013-01-01

    Classroom instruction about other cultures all too often resembles the Disney version of "It's a Small World" with Fantasyland-like cultural stereotypes, ceremonial activities, and traditional dress that can lead to serious misunderstandings about the depth and complexity of global societies. Social studies instruction presents the…

  12. Cascade quantum teleportation

    Institute of Scientific and Technical Information of China (English)

    ZHOU Nan-run; GONG Li-hua; LIU Ye

    2006-01-01

    In this letter a cascade quantum teleportation scheme is proposed. The proposed scheme needs less local quantum operations than those of quantum multi-teleportation. A quantum teleportation scheme based on entanglement swapping is presented and compared with the cascade quantum teleportation scheme. Those two schemes can effectively teleport quantum information and extend the distance of quantum communication.

  13. Nonequilibrium phase transition in directed small-world-Voronoi-Delaunay random lattices

    International Nuclear Information System (INIS)

    Lima, F.W.S.

    2016-01-01

    On directed small-world-Voronoi-Delaunay random lattices in two dimensions with quenched connectivity disorder we study the critical properties of the dynamics evolution of public opinion in social influence networks using a simple spin-like model. The system is treated by applying Monte Carlo simulations. We show that directed links on these random lattices may lead to phase diagram with first- and second-order social phase transitions out of equilibrium. (paper)

  14. Small-world effect induced by weight randomization on regular networks

    International Nuclear Information System (INIS)

    Li, Menghui; Fan, Ying; Wang, Dahui; Li, Daqing; Wu, Jinshan; Di, Zengru

    2007-01-01

    The concept of edge weight provides additional depth for describing and adjusting the properties of networks. Redistribution of edge weight can effectively change the properties of networks even though the corresponding binary topology remains unchanged. Based on regular networks with initially homogeneous dissimilarity weights, random redistribution of edge weight can be enough to induce small world phenomena. The effects of random weight redistribution on both static properties and dynamical models of networks are investigated. The results reveal that randomization of weight can enhance the ability of synchronization of chaotic systems dramatically

  15. Cascading failures in interdependent systems under a flow redistribution model

    Science.gov (United States)

    Zhang, Yingrui; Arenas, Alex; Yaǧan, Osman

    2018-02-01

    Robustness and cascading failures in interdependent systems has been an active research field in the past decade. However, most existing works use percolation-based models where only the largest component of each network remains functional throughout the cascade. Although suitable for communication networks, this assumption fails to capture the dependencies in systems carrying a flow (e.g., power systems, road transportation networks), where cascading failures are often triggered by redistribution of flows leading to overloading of lines. Here, we consider a model consisting of systems A and B with initial line loads and capacities given by {LA,i,CA ,i} i =1 n and {LB,i,CB ,i} i =1 n, respectively. When a line fails in system A , a fraction of its load is redistributed to alive lines in B , while remaining (1 -a ) fraction is redistributed equally among all functional lines in A ; a line failure in B is treated similarly with b giving the fraction to be redistributed to A . We give a thorough analysis of cascading failures of this model initiated by a random attack targeting p1 fraction of lines in A and p2 fraction in B . We show that (i) the model captures the real-world phenomenon of unexpected large scale cascades and exhibits interesting transition behavior: the final collapse is always first order, but it can be preceded by a sequence of first- and second-order transitions; (ii) network robustness tightly depends on the coupling coefficients a and b , and robustness is maximized at non-trivial a ,b values in general; (iii) unlike most existing models, interdependence has a multifaceted impact on system robustness in that interdependency can lead to an improved robustness for each individual network.

  16. Labont? Identifies Key Issues for Health Promoters in the New World Order

    OpenAIRE

    Raphael, Dennis

    2016-01-01

    For over 35 years Ronald Labonté has been critically analyzing the state of health promotion in Canada and the world. In 1981, he identified the shortcomings of the groundbreaking Lalonde Report by warning of the seductive appeal of so-called lifestyle approaches to health. Since then, he has left a trail of critical work identifying the barriers to — and opportunities for —health promotion work. More recently, he has shown how the rise of economic globalization and acceptance of neo-liberal ...

  17. A Study of the Impact of Peak Demand on Increasing Vulnerability of Cascading Failures to Extreme Contingency Events

    Energy Technology Data Exchange (ETDEWEB)

    Vyakaranam, Bharat GNVSR; Vallem, Mallikarjuna R.; Nguyen, Tony B.; Samaan, Nader A.; Berscheid, Alan P.; Makarov, Yuri V.; Diao, Ruisheng

    2017-10-02

    The vulnerability of large power systems to cascading failures and major blackouts has become evident since the Northeast blackout in 1965. Based on analyses of the series of cascading blackouts in the past decade, the research community realized the urgent need to develop better methods, tools, and practices for performing cascading-outage analysis and for evaluating mitigations that are easily accessible by utility planning engineers. PNNL has developed the Dynamic Contingency Analysis Tool (DCAT) as an open-platform and publicly available methodology to help develop applications that aim to improve the capabilities of power planning engineers to assess the impact and likelihood of extreme contingencies and potential cascading events across their systems and interconnections. DCAT analysis will help identify potential vulnerabilities and allow study of mitigation solutions to reduce the risk of cascading outages in technically sound and effective ways. Using the DCAT capability, we examined the impacts of various load conditions to identify situations in which the power grid may encounter cascading outages that could lead to potential blackouts. This paper describes the usefulness of the DCAT tool and how it helps to understand potential impacts of load demand on cascading failures on the power system.

  18. Atom land guided tour through the strange (and impossibly small) world of particle physics

    CERN Document Server

    Butterworth, Jon

    2018-01-01

    For fans of Seven Brief Lessons on Physics and Astrophysics for People in a Hurry: a richly conjured world, in map and metaphor, of particle physics. Atom Land brings the impossibly small world of particle physics to life, taking readers on a guided journey through the subatomic world. Readers will sail the subatomic seas in search of electron ports, boson continents, and hadron islands. The sea itself is the quantum field, complete with quantum waves. Beware dark energy and extra dimensions, embodied by fantastical sea creatures prowling the far edges of the known world. Your tour guide through this whimsical—and highly instructive— world is Jon Butterworth, leading physicist at CERN (the epicenter of today’s greatest findings in physics). Over a series of journeys, he shows how everything fits together, and how a grasp of particle physics is key to unlocking a deeper understanding of many of the most profound mysteries—and science’s possible answers—in the known universe.

  19. Smallest-Small-World Cellular Harmony Search for Optimization of Unconstrained Benchmark Problems

    Directory of Open Access Journals (Sweden)

    Sung Soo Im

    2013-01-01

    Full Text Available We presented a new hybrid method that combines cellular harmony search algorithms with the Smallest-Small-World theory. A harmony search (HS algorithm is based on musical performance processes that occur when a musician searches for a better state of harmony. Harmony search has successfully been applied to a wide variety of practical optimization problems. Most of the previous researches have sought to improve the performance of the HS algorithm by changing the pitch adjusting rate and harmony memory considering rate. However, there has been a lack of studies to improve the performance of the algorithm by the formation of population structures. Therefore, we proposed an improved HS algorithm that uses the cellular automata formation and the topological structure of Smallest-Small-World network. The improved HS algorithm has a high clustering coefficient and a short characteristic path length, having good exploration and exploitation efficiencies. Nine benchmark functions were applied to evaluate the performance of the proposed algorithm. Unlike the existing improved HS algorithm, the proposed algorithm is expected to have improved algorithmic efficiency from the formation of the population structure.

  20. Cascading costs: an economic nitrogen cycle.

    Science.gov (United States)

    Moomaw, William R; Birch, Melissa B L

    2005-09-01

    The chemical nitrogen cycle is becoming better characterized in terms of fluxes and reservoirs on a variety of scales. Galloway has demonstrated that reactive nitrogen can cascade through multiple ecosystems causing environmental damage at each stage before being denitrified to N(2). We propose to construct a parallel economic nitrogen cascade (ENC) in which economic impacts of nitrogen fluxes can be estimated by the costs associated with each stage of the chemical cascade. Using economic data for the benefits of damage avoided and costs of mitigation in the Chesapeake Bay basin, we have constructed an economic nitrogen cascade for the region. Since a single ton of nitrogen can cascade through the system, the costs also cascade. Therefore evaluating the benefits of mitigating a ton of reactive nitrogen released needs to consider the damage avoided in all of the ecosystems through which that ton would cascade. The analysis reveals that it is most cost effective to remove a ton of nitrogen coming from combustion since it has the greatest impact on human health and creates cascading damage through the atmospheric, terrestrial, aquatic and coastal ecosystems. We will discuss the implications of this analysis for determining the most cost effective policy option for achieving environmental quality goals.

  1. Atomic-Scale Simulations of Cascade Overlap and Damage Evolution in Silicon Carbide

    International Nuclear Information System (INIS)

    Gao, Fei; Weber, William J.

    2003-01-01

    In a previous computer simulation experiment, the accumulation of damage in SiC from the overlap of 10 keV Si displacement cascades at 200 K was investigated, and the damage states produced following each cascade were archived for further analysis. In the present study, interstitial clustering, system energy, and volume changes are investigated as the damage states evolve due to cascade overlap. An amorphous state is achieved at a damage energy density of 27.5 eV/atom (0.28 displacements per atom). At low dose levels, most defects are produced as isolated Frenkel pairs, with a small number of defect clusters involving only 4 to 6 atoms; however, after the overlap of 5 cascades (0.0125 displacements per atom), the size and number of interstitial clusters increases with increasing dose. The average energy per atom increases linearly with increasing short-range (or chemical) disorder. The volume change exhibits two regimes of linear dependence on system energy and increases more rapidly with dose than either the energy or the disorder, which indicate a significant contribution to swelling of isolated interstitials and anti-site defects. The saturation volume change for the cascade-amorphized state in these simulations is 8.2%, which is in reasonable agreement with the experimental value of 10.8% in neutron-irradiated SiC

  2. Exciton management in organic photovoltaic multidonor energy cascades.

    Science.gov (United States)

    Griffith, Olga L; Forrest, Stephen R

    2014-05-14

    Multilayer donor regions in organic photovoltaics show improved power conversion efficiency when arranged in decreasing exciton energy order from the anode to the acceptor interface. These so-called "energy cascades" drive exciton transfer from the anode to the dissociating interface while reducing exciton quenching and allowing improved overlap with the solar spectrum. Here we investigate the relative importance of exciton transfer and blocking in a donor cascade employing diphenyltetracene (D1), rubrene (D2), and tetraphenyldibenzoperiflanthene (D3) whose optical gaps monotonically decrease from D1 to D3. In this structure, D1 blocks excitons from quenching at the anode, D2 accepts transfer of excitons from D1 and blocks excitons at the interface between D2 and D3, and D3 contributes the most to the photocurrent due to its strong absorption at visible wavelengths, while also determining the open circuit voltage. We observe singlet exciton Förster transfer from D1 to D2 to D3 consistent with cascade operation. The power conversion efficiency of the optimized cascade OPV with a C60 acceptor layer is 7.1 ± 0.4%, which is significantly higher than bilayer devices made with only the individual donors. We develop a quantitative model to identify the dominant exciton processes that govern the photocurrent generation in multilayer organic structures.

  3. Phase 1 Feasibility Study, Canby Cascaded Geothermal Project, April 2, 2013

    Energy Technology Data Exchange (ETDEWEB)

    Merrick, Dale E [CanbyGeo, LLC

    2013-04-02

    A small community in Northern California is attempting to use a local geothermal resource to generate electrical power and cascade residual energy to an existing geothermal district heating system, greenhouse, and future fish farm and subsequent reinjection into the geothermal aquifer, creating a net-zero energy community, not including transportation.

  4. Search for Astrophysical Sources of Neutrinos Using Cascade Events in IceCube

    Energy Technology Data Exchange (ETDEWEB)

    Aartsen, M. G. [Department of Physics, University of Adelaide, Adelaide, 5005 (Australia); Ackermann, M. [DESY, D-15735 Zeuthen (Germany); Adams, J.; Bagherpour, H. [Dept. of Physics and Astronomy, University of Canterbury, Private Bag 4800, Christchurch (New Zealand); Aguilar, J. A.; Ansseau, I. [Université Libre de Bruxelles, Science Faculty CP230, B-1050 Brussels (Belgium); Ahlers, M. [Niels Bohr Institute, University of Copenhagen, DK-2100 Copenhagen (Denmark); Ahrens, M. [Oskar Klein Centre and Dept. of Physics, Stockholm University, SE-10691 Stockholm (Sweden); Al Samarai, I. [Département de physique nucléaire et corpusculaire, Université de Genève, CH-1211 Genève (Switzerland); Altmann, D.; Anton, G. [Erlangen Centre for Astroparticle Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91058 Erlangen (Germany); Andeen, K. [Department of Physics, Marquette University, Milwaukee, WI, 53201 (United States); Anderson, T. [Dept. of Physics, Pennsylvania State University, University Park, PA 16802 (United States); Argüelles, C.; Axani, S. [Dept. of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Auffenberg, J. [III. Physikalisches Institut, RWTH Aachen University, D-52056 Aachen (Germany); Bai, X. [Physics Department, South Dakota School of Mines and Technology, Rapid City, SD 57701 (United States); Barwick, S. W. [Dept. of Physics and Astronomy, University of California, Irvine, CA 92697 (United States); Baum, V. [Institute of Physics, University of Mainz, Staudinger Weg 7, D-55099 Mainz (Germany); Collaboration: IceCube Collaboration; and others

    2017-09-10

    The IceCube neutrino observatory has established the existence of a flux of high-energy astrophysical neutrinos, which is inconsistent with the expectation from atmospheric backgrounds at a significance greater than 5 σ . This flux has been observed in analyses of both track events from muon neutrino interactions and cascade events from interactions of all neutrino flavors. Searches for astrophysical neutrino sources have focused on track events due to the significantly better angular resolution of track reconstructions. To date, no such sources have been confirmed. Here we present the first search for astrophysical neutrino sources using cascades interacting in IceCube with deposited energies as small as 1 TeV. No significant clustering was observed in a selection of 263 cascades collected from 2010 May to 2012 May. We show that compared to the classic approach using tracks, this statistically independent search offers improved sensitivity to sources in the southern sky, especially if the emission is spatially extended or follows a soft energy spectrum. This enhancement is due to the low background from atmospheric neutrinos forming cascade events and the additional veto of atmospheric neutrinos at declinations ≲−30°.

  5. Quantification of the glycogen cascade system: the ultrasensitive responses of liver glycogen synthase and muscle phosphorylase are due to distinctive regulatory designs

    Directory of Open Access Journals (Sweden)

    Venkatesh KV

    2005-05-01

    Full Text Available Abstract Background Signaling pathways include intricate networks of reversible covalent modification cycles. Such multicyclic enzyme cascades amplify the input stimulus, cause integration of multiple signals and exhibit sensitive output responses. Regulation of glycogen synthase and phosphorylase by reversible covalent modification cycles exemplifies signal transduction by enzyme cascades. Although this system for regulating glycogen synthesis and breakdown appears similar in all tissues, subtle differences have been identified. For example, phosphatase-1, a dephosphorylating enzyme of the system, is regulated quite differently in muscle and liver. Do these small differences in regulatory architecture affect the overall performance of the glycogen cascade in a specific tissue? We address this question by analyzing the regulatory structure of the glycogen cascade system in liver and muscle cells at steady state. Results The glycogen cascade system in liver and muscle cells was analyzed at steady state and the results were compared with literature data. We found that the cascade system exhibits highly sensitive switch-like responses to changes in cyclic AMP concentration and the outputs are surprisingly different in the two tissues. In muscle, glycogen phosphorylase is more sensitive than glycogen synthase to cyclic AMP, while the opposite is observed in liver. Furthermore, when the liver undergoes a transition from starved to fed-state, the futile cycle of simultaneous glycogen synthesis and degradation switches to reciprocal regulation. Under such a transition, different proportions of active glycogen synthase and phosphorylase can coexist due to the varying inhibition of glycogen-synthase phosphatase by active phosphorylase. Conclusion The highly sensitive responses of glycogen synthase in liver and phosphorylase in muscle to primary stimuli can be attributed to distinctive regulatory designs in the glycogen cascade system. The different

  6. Small Worlds Week: An online celebration of planetary science using social media to reach millions

    Science.gov (United States)

    Mayo, Louis

    2015-11-01

    In celebration of the many recent discoveries from New Horizons, Dawn, Rosetta, and Cassini, NASA launched Small Worlds Week, an online, social media driven outreach program leveraging the infrastructure of Sun-Earth Days that included a robust web design, exemplary education materials, hands-on fun activities, multimedia resources, science and career highlights, and a culminating social media event. Each day from July 6-9, a new class of solar system small worlds was featured on the website: Monday-comets, Tuesday-asteroids, Wednesday-icy moons, and Thursday-dwarf planets. Then on Friday, July 10, nine scientists from Goddard Space Flight Center, Jet Propulsion Laboratory, Naval Research Laboratory, and Lunar and Planetary Institute gathered online for four hours to answer questions from the public via Facebook and Twitter. Throughout the afternoon the scientists worked closely with a social media expert and several summer interns to reply to inquirers and to archive their chats. By all accounts, Small Worlds Week was a huge success with 37 million potential views of the social media Q&A posts. The group plans to improve and replicate the program during the school year with a more classroom focus, and then to build and extend the program to be held every year. For more information, visit http:// sunearthday.nasa.gov or catch us on Twitter, #nasasww.

  7. Abnormal small-world brain functional networks in obsessive-compulsive disorder patients with poor insight.

    Science.gov (United States)

    Lei, Hui; Cui, Yan; Fan, Jie; Zhang, Xiaocui; Zhong, Mingtian; Yi, Jinyao; Cai, Lin; Yao, Dezhong; Zhu, Xiongzhao

    2017-09-01

    There are limited data on neurobiological correlates of poor insight in obsessive-compulsive disorder (OCD). This study explored whether specific changes occur in small-world network (SWN) properties in the brain functional network of OCD patients with poor insight. Resting-state electroencephalograms (EEGs) were recorded for 12 medication-free OCD patients with poor insight, 50 medication-free OCD patients with good insight, and 36 healthy controls. Both of the OCD groups exhibited topological alterations in the brain functional network characterized by abnormal small-world parameters at the beta band. However, the alterations at the theta band only existed in the OCD patients with poor insight. A relatively small sample size. Subjects were naïve to medications and those with Axis I comorbidity were excluded, perhaps limiting generalizability. Disrupted functional integrity at the beta bands of the brain functional network may be related to OCD, while disrupted functional integrity at the theta band may be associated with poor insight in OCD patients, thus this study might provide novel insight into our understanding of the pathophysiology of OCD. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Impaired small-world network efficiency and dynamic functional distribution in patients with cirrhosis.

    Directory of Open Access Journals (Sweden)

    Tun-Wei Hsu

    Full Text Available Hepatic encephalopathy (HE is a complex neuropsychiatric syndrome and a major complication of liver cirrhosis. Dysmetabolism of the brain, related to elevated ammonia levels, interferes with intercortical connectivity and cognitive function. For evaluation of network efficiency, a 'small-world' network model can quantify the effectiveness of information transfer within brain networks. This study aimed to use small-world topology to investigate abnormalities of neuronal connectivity among widely distributed brain regions in patients with liver cirrhosis using resting-state functional magnetic resonance imaging (rs-fMRI. Seventeen cirrhotic patients without HE, 9 with minimal HE, 9 with overt HE, and 35 healthy controls were compared. The interregional correlation matrix was obtained by averaging the rs-fMRI time series over all voxels in each of the 90 regions using the automated anatomical labeling model. Cost and correlation threshold values were then applied to construct the functional brain network. The absolute and relative network efficiencies were calculated; quantifying distinct aspects of the local and global topological network organization. Correlations between network topology parameters, ammonia levels, and the severity of HE were determined using linear regression and ANOVA. The local and global topological efficiencies of the functional connectivity network were significantly disrupted in HE patients; showing abnormal small-world properties. Alterations in regional characteristics, including nodal efficiency and nodal strength, occurred predominantly in the association, primary, and limbic/paralimbic regions. The degree of network organization disruption depended on the severity of HE. Ammonia levels were also significantly associated with the alterations in local network properties. Results indicated that alterations in the rs-fMRI network topology of the brain were associated with HE grade; and that focal or diffuse lesions

  9. Markov models for fMRI correlation structure: Is brain functional connectivity small world, or decomposable into networks?

    Science.gov (United States)

    Varoquaux, G; Gramfort, A; Poline, J B; Thirion, B

    2012-01-01

    Correlations in the signal observed via functional Magnetic Resonance Imaging (fMRI), are expected to reveal the interactions in the underlying neural populations through hemodynamic response. In particular, they highlight distributed set of mutually correlated regions that correspond to brain networks related to different cognitive functions. Yet graph-theoretical studies of neural connections give a different picture: that of a highly integrated system with small-world properties: local clustering but with short pathways across the complete structure. We examine the conditional independence properties of the fMRI signal, i.e. its Markov structure, to find realistic assumptions on the connectivity structure that are required to explain the observed functional connectivity. In particular we seek a decomposition of the Markov structure into segregated functional networks using decomposable graphs: a set of strongly-connected and partially overlapping cliques. We introduce a new method to efficiently extract such cliques on a large, strongly-connected graph. We compare methods learning different graph structures from functional connectivity by testing the goodness of fit of the model they learn on new data. We find that summarizing the structure as strongly-connected networks can give a good description only for very large and overlapping networks. These results highlight that Markov models are good tools to identify the structure of brain connectivity from fMRI signals, but for this purpose they must reflect the small-world properties of the underlying neural systems. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Genetic algorithm based separation cascade optimization

    International Nuclear Information System (INIS)

    Mahendra, A.K.; Sanyal, A.; Gouthaman, G.; Bera, T.K.

    2008-01-01

    The conventional separation cascade design procedure does not give an optimum design because of squaring-off, variation of flow rates and separation factor of the element with respect to stage location. Multi-component isotope separation further complicates the design procedure. Cascade design can be stated as a constrained multi-objective optimization. Cascade's expectation from the separating element is multi-objective i.e. overall separation factor, cut, optimum feed and separative power. Decision maker may aspire for more comprehensive multi-objective goals where optimization of cascade is coupled with the exploration of separating element optimization vector space. In real life there are many issues which make it important to understand the decision maker's perception of cost-quality-speed trade-off and consistency of preferences. Genetic algorithm (GA) is one such evolutionary technique that can be used for cascade design optimization. This paper addresses various issues involved in the GA based multi-objective optimization of the separation cascade. Reference point based optimization methodology with GA based Pareto optimality concept for separation cascade was found pragmatic and promising. This method should be explored, tested, examined and further developed for binary as well as multi-component separations. (author)

  11. MD simulation of atomic displacement cascades near chromium-rich clusters in FeCr alloy

    International Nuclear Information System (INIS)

    Tikhonchev, M.; Svetukhin, V.; Gaganidze, E.

    2013-01-01

    The paper reports simulation of cascades in Fe–9 at.%Cr binary alloy containing chromium-rich clusters. The simulation is performed by the molecular dynamics method at the initial temperature of 300 K and primary knock-on atom energy of 15 and 20 keV. Spherical clusters containing 95 at.% of Cr with diameter of 1–5 nm have been considered. The properties of cascade evolution in the presence of chromium-rich cluster are studied. It is shown that these clusters tend to dissolve in collision cascades. However, clusters with diameter of ⩾3 nm exhibit only slight modifications and can be considered stable. Parameters of small (1–2 nm) clusters can change significantly and, in some cases, a 1 nm cluster can be totally dissolved

  12. MD simulation of atomic displacement cascades near chromium-rich clusters in FeCr alloy

    Energy Technology Data Exchange (ETDEWEB)

    Tikhonchev, M., E-mail: tikhonchev@sv.ulsu.ru [Ulyanovsk State University, Research Institute of Technology, 42 Leo Tolstoy St., 432970 Ulyanovsk (Russian Federation); Svetukhin, V. [Ulyanovsk State University, Research Institute of Technology, 42 Leo Tolstoy St., 432970 Ulyanovsk (Russian Federation); Gaganidze, E. [Karlsruhe Institute of Technology, Institute for Applied Materials, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Karlsruhe (Germany)

    2013-11-15

    The paper reports simulation of cascades in Fe–9 at.%Cr binary alloy containing chromium-rich clusters. The simulation is performed by the molecular dynamics method at the initial temperature of 300 K and primary knock-on atom energy of 15 and 20 keV. Spherical clusters containing 95 at.% of Cr with diameter of 1–5 nm have been considered. The properties of cascade evolution in the presence of chromium-rich cluster are studied. It is shown that these clusters tend to dissolve in collision cascades. However, clusters with diameter of ⩾3 nm exhibit only slight modifications and can be considered stable. Parameters of small (1–2 nm) clusters can change significantly and, in some cases, a 1 nm cluster can be totally dissolved.

  13. The Topological Analysis of Urban Transit System as a Small-World Network

    OpenAIRE

    Zhaosheng Yang; Huxing Zhou; Peng Gao; Hong Chen; Nan Zhang

    2011-01-01

    This paper proposes a topological analysis of urban transit system based on a functional representation network constructed from the urban transit system in Beijing. The representation gives a functional view on nodes named a transit line. Statistical measures are computed and introduced in complex network analysis. It shows that the urban transit system forms small-world networks and exhibits properties different from random networks and regular networks. Furthermore, the topological propert...

  14. Ion-implantation dense cascade data

    International Nuclear Information System (INIS)

    Winterbon, K.B.

    1983-04-01

    A tabulation is given of data useful in estimating various aspects of ion-implantation cascades in the nuclear stopping regime, particularly with respect to nonlinearity of the cascade at high energy densities. The tabulation is restricted to self-ion implantation. Besides power-cross-section cascade dimensions, various material properties are included. Scaling of derived quantities with input data is noted, so one is not limited to the values assumed by the author

  15. PROJECT CASCADES OF SMALL DRY RESERVOIRS FOR FLOOD PROTECTION OF URBAN AREAS

    Directory of Open Access Journals (Sweden)

    Rafał Antoszewski

    2017-02-01

    Full Text Available The paper presents the problem of designing an open reservoirs with a capacity of about 100 000 m3 in heavily urbanized areas of anthropogenically transformed natural watercourses with numerous outlets drainage and large sealed surfaces runoff. In particular the issues of the hydrological basics design based on the meteorological data in the catchment uncontrolled water level checkpoints with particular emphasis on the tools of computer-aided modeling of hydrological processes (HEC-HMS, HEC-RAS and available for use mathematical models and statistical rainfall-runoff, this practical the method SCS-CN and linear model cascade tanks Nash to transform the effective precipitation in surface runoff.

  16. Design-theoretical study of cascade CO2 sub-critical mechanical compression/butane ejector cooling cycle

    KAUST Repository

    Petrenko, V.O.

    2011-11-01

    In this paper an innovative micro-trigeneration system composed of a cogeneration system and a cascade refrigeration cycle is proposed. The cogeneration system is a combined heat and power system for electricity generation and heat production. The cascade refrigeration cycle is the combination of a CO2 mechanical compression refrigerating machine (MCRM), powered by generated electricity, and an ejector cooling machine (ECM), driven by waste heat and using refrigerant R600. Effect of the cycle operating conditions on ejector and ejector cycle performances is studied. Optimal geometry of the ejector and performance characteristics of ECM are determined at wide range of the operating conditions. The paper also describes a theoretical analysis of the CO2 sub-critical cycle and shows the effect of the MCRM evaporating temperature on the cascade system performance. The obtained data provide necessary information to design a small-scale cascade system with cooling capacity of 10 kW for application in micro-trigeneration systems. © 2010 Elsevier Ltd and IIR. All rights reserved.

  17. Frozen waterfall (or ice cascade) growth and decay: a thermodynamic approach

    Science.gov (United States)

    Gauthier, Francis; Montagnat, Maurine; Weiss, Jérôme; Allard, Michel; Hétu, Bernard

    2013-04-01

    The ice volume evolution of an ice cascade was studied using a thermodynamic model. The model was developed from meteorological data collected in the vicinity of the waterfall and validated from ice volume measurements estimated from terrestrial LiDAR images. The ice cascade forms over a 45 m high rockwall located in northern Gaspésie, Québec, Canada. Two stages of formation were identified. During the first stage, the growth is mainly controlled by air convection around the flowing and freefalling water. The ice cascade growth rate increases with the decreasing air temperature below 0°C and when the water flow reaches its lowest level. During the second stage, the ice cascade covers the entire rockwall surface, water flow is isolated from the outside environment and ice volume increases asymptotically. Heat is evacuated from the water flow through the ice cover by conduction. The growth is mainly controlled by the radiation energy balance but more specifically by the longwave radiation emitted at the ice surface during the night. In spring, melting of the ice cascade is clearly dependant on the sensible heat carried by the increasing water flow and the diffuse solar radiation received at the ice surface during the day.

  18. Cascade phenomenon against subsequent failures in complex networks

    Science.gov (United States)

    Jiang, Zhong-Yuan; Liu, Zhi-Quan; He, Xuan; Ma, Jian-Feng

    2018-06-01

    Cascade phenomenon may lead to catastrophic disasters which extremely imperil the network safety or security in various complex systems such as communication networks, power grids, social networks and so on. In some flow-based networks, the load of failed nodes can be redistributed locally to their neighboring nodes to maximally preserve the traffic oscillations or large-scale cascading failures. However, in such local flow redistribution model, a small set of key nodes attacked subsequently can result in network collapse. Then it is a critical problem to effectively find the set of key nodes in the network. To our best knowledge, this work is the first to study this problem comprehensively. We first introduce the extra capacity for every node to put up with flow fluctuations from neighbors, and two extra capacity distributions including degree based distribution and average distribution are employed. Four heuristic key nodes discovering methods including High-Degree-First (HDF), Low-Degree-First (LDF), Random and Greedy Algorithms (GA) are presented. Extensive simulations are realized in both scale-free networks and random networks. The results show that the greedy algorithm can efficiently find the set of key nodes in both scale-free and random networks. Our work studies network robustness against cascading failures from a very novel perspective, and methods and results are very useful for network robustness evaluations and protections.

  19. Inclusive Rates and Spectra of the Lambda, Cascade, and Omega Hyperons atBaBar

    Energy Technology Data Exchange (ETDEWEB)

    Chien, Andrew L. [Stanford Univ., CA (United States)

    2008-01-01

    We employ Runs 1-4 off-peak data sample (about 21.5 fb-1) to produce the current world-best spectra and production rates measurements for three strangely-flavored baryons: the Λ hyperon, the cascade hyperon, and the Ω hyperon. These improved measurements shall enable theoretical and phenomelogical workers to generate more realistic models for the hadronization process, currently one of the unresolved problem areas in the standard model of particle physics. This analysis was conducted using codes from release 16 series. We report the production rate at 10.54 GeV for the Λ as 0.0900 ± 0.0006(stat.) ± 0.0039(sys.) per hadronic event. Our measured production rate at the same energy for the cascade hyperon is 0.00562 ± 0.00013(stat.) ± 0.00045(sys.) per hadronic event, while that for the Ω hyperon is 0.00027 ± 0.00004(stat.) ± 0.0008(sys.) per hadronic event. The spectral measurements for the respective particles also constitute current world-best measurements.

  20. Inclusive Rates and Spectra of the Lambda, Cascade, and Omega Hyperons at BaBar

    International Nuclear Information System (INIS)

    Chien, A

    2008-01-01

    We employ Runs 1-4 off-peak data sample (about 21.5 fb -1 ) to produce the current world-best spectra and production rates measurements for three strangely-flavored baryons: the Λ hyperon, the cascade hyperon, and the (Omega) hyperon. These improved measurements shall enable theoretical and phenomelogical workers to generate more realistic models for the hadronization process, currently one of the unresolved problem areas in the standard model of particle physics. This analysis was conducted using codes from release 16 series. We report the production rate at 10.54 GeV for the Λ as 0.0900 ± 0.0006(stat.) ± 0.0039(sys.) per hadronic event. Our measured production rate at the same energy for the cascade hyperon is 0.00562 ± 0.00013(stat.) ± 0.00045(sys.) per hadronic event, while that for the (Omega) hyperon is 0.00027 ± 0.00004(stat.) ± 0.0008(sys.) per hadronic event. The spectral measurements for the respective particles also constitute current world-best measurements

  1. Hadron cascades produced by electromagnetic cascades

    International Nuclear Information System (INIS)

    Nelson, W.R.; Jenkins, T.M.; Ranft, J.

    1986-12-01

    A method for calculating high energy hadron cascades induced by multi-GeV electron and photon beams is described. Using the EGS4 computer program, high energy photons in the EM shower are allowed to interact hadronically according to the vector meson dominance (VMD) model, facilitated by a Monte Carlo version of the dual multistring fragmentation model which is used in the hadron cascade code FLUKA. The results of this calculation compare very favorably with experimental data on hadron production in photon-proton collisions and on the hadron production by electron beams on targets (i.e., yields in secondary particle beam lines). Electron beam induced hadron star density contours are also presented and are compared with those produced by proton beams. This FLUKA-EGS4 coupling technique could find use in the design of secondary beams, in the determination high energy hadron source terms for shielding purposes, and in the estimation of induced radioactivity in targets, collimators and beam dumps

  2. Cascade Organic Solar Cells

    KAUST Repository

    Schlenker, Cody W.

    2011-09-27

    We demonstrate planar organic solar cells consisting of a series of complementary donor materials with cascading exciton energies, incorporated in the following structure: glass/indium-tin-oxide/donor cascade/C 60/bathocuproine/Al. Using a tetracene layer grown in a descending energy cascade on 5,6-diphenyl-tetracene and capped with 5,6,11,12-tetraphenyl- tetracene, where the accessibility of the π-system in each material is expected to influence the rate of parasitic carrier leakage and charge recombination at the donor/acceptor interface, we observe an increase in open circuit voltage (Voc) of approximately 40% (corresponding to a change of +200 mV) compared to that of a single tetracene donor. Little change is observed in other parameters such as fill factor and short circuit current density (FF = 0.50 ± 0.02 and Jsc = 2.55 ± 0.23 mA/cm2) compared to those of the control tetracene-C60 solar cells (FF = 0.54 ± 0.02 and Jsc = 2.86 ± 0.23 mA/cm2). We demonstrate that this cascade architecture is effective in reducing losses due to polaron pair recombination at donor-acceptor interfaces, while enhancing spectral coverage, resulting in a substantial increase in the power conversion efficiency for cascade organic photovoltaic cells compared to tetracene and pentacene based devices with a single donor layer. © 2011 American Chemical Society.

  3. Cascade Organic Solar Cells

    KAUST Repository

    Schlenker, Cody W.; Barlier, Vincent S.; Chin, Stephanie W.; Whited, Matthew T.; McAnally, R. Eric; Forrest, Stephen R.; Thompson, Mark E.

    2011-01-01

    We demonstrate planar organic solar cells consisting of a series of complementary donor materials with cascading exciton energies, incorporated in the following structure: glass/indium-tin-oxide/donor cascade/C 60/bathocuproine/Al. Using a tetracene layer grown in a descending energy cascade on 5,6-diphenyl-tetracene and capped with 5,6,11,12-tetraphenyl- tetracene, where the accessibility of the π-system in each material is expected to influence the rate of parasitic carrier leakage and charge recombination at the donor/acceptor interface, we observe an increase in open circuit voltage (Voc) of approximately 40% (corresponding to a change of +200 mV) compared to that of a single tetracene donor. Little change is observed in other parameters such as fill factor and short circuit current density (FF = 0.50 ± 0.02 and Jsc = 2.55 ± 0.23 mA/cm2) compared to those of the control tetracene-C60 solar cells (FF = 0.54 ± 0.02 and Jsc = 2.86 ± 0.23 mA/cm2). We demonstrate that this cascade architecture is effective in reducing losses due to polaron pair recombination at donor-acceptor interfaces, while enhancing spectral coverage, resulting in a substantial increase in the power conversion efficiency for cascade organic photovoltaic cells compared to tetracene and pentacene based devices with a single donor layer. © 2011 American Chemical Society.

  4. Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade

    Directory of Open Access Journals (Sweden)

    Chaoyou Xue

    2017-12-01

    Full Text Available CRISPR-Cas systems defend bacteria and archaea against infection by bacteriophage and other threats. The central component of these systems are surveillance complexes that use guide RNAs to bind specific regions of foreign nucleic acids, marking them for destruction. Surveillance complexes must locate targets rapidly to ensure timely immune response, but the mechanism of this search process remains unclear. Here, we used single-molecule FRET to visualize how the type I-E surveillance complex Cascade searches DNA in real time. Cascade rapidly and randomly samples DNA through nonspecific electrostatic contacts, pausing at short PAM recognition sites that may be adjacent to the target. We identify Cascade motifs that are essential for either nonspecific sampling or positioning and readout of the PAM. Our findings provide a comprehensive structural and kinetic model for the Cascade target-search mechanism, revealing how CRISPR surveillance complexes can rapidly search large amounts of genetic material en route to target recognition.

  5. The Tuberculosis Cascade of Care in India’s Public Sector: A Systematic Review and Meta-analysis

    Science.gov (United States)

    Satyanarayana, Srinath; Pai, Madhukar; Thomas, Beena E.; Chadha, Vineet K.; Swaminathan, Soumya; Mayer, Kenneth H.

    2016-01-01

    Background India has 23% of the global burden of active tuberculosis (TB) patients and 27% of the world’s “missing” patients, which includes those who may not have received effective TB care and could potentially spread TB to others. The “cascade of care” is a useful model for visualizing deficiencies in case detection and retention in care, in order to prioritize interventions. Methods and Findings The care cascade constructed in this paper focuses on the Revised National TB Control Programme (RNTCP), which treats about half of India’s TB patients. We define the TB cascade as including the following patient populations: total prevalent active TB patients in India, TB patients who reach and undergo evaluation at RNTCP diagnostic facilities, patients successfully diagnosed with TB, patients who start treatment, patients retained to treatment completion, and patients who achieve 1-y recurrence-free survival. We estimate each step of the cascade for 2013 using data from two World Health Organization (WHO) reports (2014–2015), one WHO dataset (2015), and three RNTCP reports (2014–2016). In addition, we conduct three targeted systematic reviews of the scientific literature to identify 39 unique articles published from 2000–2015 that provide additional data on five indicators that help estimate different steps of the TB cascade. We construct separate care cascades for the overall population of patients with active TB and for patients with specific forms of TB—including new smear-positive, new smear-negative, retreatment smear-positive, and multidrug-resistant (MDR) TB. The WHO estimated that there were 2,700,000 (95%CI: 1,800,000–3,800,000) prevalent TB patients in India in 2013. Of these patients, we estimate that 1,938,027 (72%) TB patients were evaluated at RNTCP facilities; 1,629,906 (60%) were successfully diagnosed; 1,417,838 (53%) got registered for treatment; 1,221,764 (45%) completed treatment; and 1,049,237 (95%CI: 1,008,775–1

  6. Monte Carlo tests of small-world architecture for coarse-grained networks of the United States railroad and highway transportation systems

    Science.gov (United States)

    Aldrich, Preston R.; El-Zabet, Jermeen; Hassan, Seerat; Briguglio, Joseph; Aliaj, Enela; Radcliffe, Maria; Mirza, Taha; Comar, Timothy; Nadolski, Jeremy; Huebner, Cynthia D.

    2015-11-01

    Several studies have shown that human transportation networks exhibit small-world structure, meaning they have high local clustering and are easily traversed. However, some have concluded this without statistical evaluations, and others have compared observed structure to globally random rather than planar models. Here, we use Monte Carlo randomizations to test US transportation infrastructure data for small-worldness. Coarse-grained network models were generated from GIS data wherein nodes represent the 3105 contiguous US counties and weighted edges represent the number of highway or railroad links between counties; thus, we focus on linkage topologies and not geodesic distances. We compared railroad and highway transportation networks with a simple planar network based on county edge-sharing, and with networks that were globally randomized and those that were randomized while preserving their planarity. We conclude that terrestrial transportation networks have small-world architecture, as it is classically defined relative to global randomizations. However, this topological structure is sufficiently explained by the planarity of the graphs, and in fact the topological patterns established by the transportation links actually serve to reduce the amount of small-world structure.

  7. First time measurements of polarization observables for the charged cascade hyperon in photoproduction

    Energy Technology Data Exchange (ETDEWEB)

    Bono, Jason [Florida Intl Univ., Miami, FL (United States)

    2014-08-31

    The parity violating weak decay of hyperons offers a valuable means of measuring their polarization, providing insight into the production of strange quarks and the matter they compose. Jefferson Lab's CLAS collaboration has utilized this property of hyperons, publishing the most precise polarization measurements for the Lambda and Sigma in both photoproduction and electroproduction to date. In contrast, cascades, which contain two strange quarks, can only be produced through indirect processes and as a result, exhibit low cross sections thus remaining experimentally elusive.

    At present, there are two aspects in cascade physics where progress has been minimal: characterizing their production mechanism, which lacks theoretical and experimental developments, and observation of the numerous excited cascade resonances that are required to exist by flavor SU(3)F symmetry. However, CLAS data were collected in 2008 with a luminosity of 68 pb^-1 using a circularly polarized photon beam with energies up to 5.45 GeV, incident on a liquid hydrogen target. This dataset is, at present, the world's largest for meson photoproduction in its energy range and provides a unique opportunity to study cascade physics with polarization measurements.

    The current analysis explores hyperon production through the yp -> K^+ K^+ Xi^- reaction by providing the first ever determination of spin observables P, Cx and Cz for the cascade. Three of our primary goals are to test the only cascade photoproduction model in existence, examine the underlying processes that give rise to hyperon polarization, and to stimulate future theoretical developments while providing constraints for their parameters. Our research is part of a broader program to understand the production of strange quarks and hadrons with strangeness. The remainder of this document discusses the motivation behind such research, the method of data collection, details of their analysis, and the significance of

  8. "Price-quakes" shaking the world's stock exchanges.

    Directory of Open Access Journals (Sweden)

    Jørgen Vitting Andersen

    Full Text Available BACKGROUND: Systemic risk has received much more awareness after the excessive risk taking by major financial instituations pushed the world's financial system into what many considered a state of near systemic failure in 2008. The IMF for example in its yearly 2009 Global Financial Stability Report acknowledged the lack of proper tools and research on the topic. Understanding how disruptions can propagate across financial markets is therefore of utmost importance. METHODOLOGY/PRINCIPAL FINDINGS: Here, we use empirical data to show that the world's markets have a non-linear threshold response to events, consistent with the hypothesis that traders exhibit change blindness. Change blindness is the tendency of humans to ignore small changes and to react disproportionately to large events. As we show, this may be responsible for generating cascading events--pricequakes--in the world's markets. We propose a network model of the world's stock exchanges that predicts how an individual stock exchange should be priced in terms of the performance of the global market of exchanges, but with change blindness included in the pricing. The model has a direct correspondence to models of earth tectonic plate movements developed in physics to describe the slip-stick movement of blocks linked via spring forces. CONCLUSIONS/SIGNIFICANCE: We have shown how the price dynamics of the world's stock exchanges follows a dynamics of build-up and release of stress, similar to earthquakes. The nonlinear response allows us to classify price movements of a given stock index as either being generated internally, due to specific economic news for the country in question, or externally, by the ensemble of the world's stock exchanges reacting together like a complex system. The model may provide new insight into the origins and thereby also prevent systemic risks in the global financial network.

  9. "Price-quakes" shaking the world's stock exchanges.

    Science.gov (United States)

    Andersen, Jørgen Vitting; Nowak, Andrzej; Rotundo, Giulia; Parrott, Lael; Martinez, Sebastian

    2011-01-01

    Systemic risk has received much more awareness after the excessive risk taking by major financial instituations pushed the world's financial system into what many considered a state of near systemic failure in 2008. The IMF for example in its yearly 2009 Global Financial Stability Report acknowledged the lack of proper tools and research on the topic. Understanding how disruptions can propagate across financial markets is therefore of utmost importance. Here, we use empirical data to show that the world's markets have a non-linear threshold response to events, consistent with the hypothesis that traders exhibit change blindness. Change blindness is the tendency of humans to ignore small changes and to react disproportionately to large events. As we show, this may be responsible for generating cascading events--pricequakes--in the world's markets. We propose a network model of the world's stock exchanges that predicts how an individual stock exchange should be priced in terms of the performance of the global market of exchanges, but with change blindness included in the pricing. The model has a direct correspondence to models of earth tectonic plate movements developed in physics to describe the slip-stick movement of blocks linked via spring forces. We have shown how the price dynamics of the world's stock exchanges follows a dynamics of build-up and release of stress, similar to earthquakes. The nonlinear response allows us to classify price movements of a given stock index as either being generated internally, due to specific economic news for the country in question, or externally, by the ensemble of the world's stock exchanges reacting together like a complex system. The model may provide new insight into the origins and thereby also prevent systemic risks in the global financial network.

  10. Progress of research on the mechanism of microstructure evolution during irradiation with collision cascades

    International Nuclear Information System (INIS)

    Kiritani, Michio

    1997-01-01

    Progress of the research on microstructural evolution during radiation damage accompanied with collision cascades, particularly by neutrons, is summarized from the researches reported in 1995 and 1996. The major part of irradiation was performed with JMTR (Japan Material Testing Reactor), and comparisons were made with the result of D-T fusion neutron irradiation with RTNS-II (Rotating Target Neutron Source, LLNL). The subjects concerned are: (1) Microstructure evolution during irradiation, (2) Processes controlling the accumulation of defects during cascade damage, (3) Subcascades from the viewpoint of point defect cluster formation, (4) Mechanism of suppression of microstructure evolution during temperature cycle neutron irradiation of nickel, (5) Identification of the nature of neutron-irradiation-induced point defect clusters in copper by means of electron irradiation, (6) Easy one-dimensional motion of small interstitial clusters, (7) Identification of the nature of small point defect clusters in neutron irradiated Fe-16Ni-15Cr, (8) Spatial distribution of nucleation of point defect clusters by high energy particle irradiation, (9) Crystallographic orientation dependence of dislocation structures in neutron irradiated metals, (10) Examination of defect accumulation mode with multi-section-removable-irradiation-rig in Japan Material Testing Reactor, (11) Estimation of freely migrating point defects during cascade damage by the growth of helical dislocations, (12) Identification of the nature of neutron-irradiation-induced small point defect clusters in Nickel by means of electron irradiation, (13) Thermal stability of point defect clusters in neutron irradiated Fe-16Ni-15Cr. (author)

  11. Freely-migrating defects: Their production and interaction with cascade remnants

    International Nuclear Information System (INIS)

    Rehn, L.E.; Wiedersich, H.

    1991-05-01

    Many microstructural changes that occur during irradiation are driven primarily by freely-migrating defects, i.e. those defects which escape from nascent cascades to migrate over distances that are large relative to typical cascade dimensions. Several measurements during irradiation at elevated temperatures have shown that the survival rate of freely-migrating defects decreases much more strongly with increasing primary recoil energy than does the survival rate for defects generated at liquid helium temperatures. For typical fission or fusion recoil spectra, and for heavy-ion bombardment, the fraction of defects that migrate long-distances is apparently only ∼1% of the calculated dpa. This small surviving fraction of freely-migrating defects results at least partially from additional intracascade recombination at elevated temperatures. However, cascade remnants, e.g., vacancy and interstitial clusters, also contribute by enhancing intercascade defect annihilation. A recently developed rate-theory approach is used to discuss the relative importance of intra- and intercascade recombination to the survival rate of freely-migrating defects. Within the validity of certain simplifying assumptions, the additional sink density provided by defect clusters produced directly within individual cascades can explain the difference between a defect survival rate of about 30% for low dose, low temperature irradiations with heavy ions, and a survival rate of only ∼1% for freely-migrating defects at elevated temperatures. The status of our current understanding of freely-migrating defects, including remaining unanswered questions, is also discussed. 33 refs., 5 figs

  12. A hybrid small-world network/semi-physical model for predicting wildfire spread in heterogeneous landscapes

    International Nuclear Information System (INIS)

    Billaud, Y; Kaiss, A; Drissi, M; Pizzo, Y; Porterie, B; Zekri, N; Acem, Z; Collin, A; Boulet, P; Santoni, P-A; Bosseur, F

    2012-01-01

    This paper presents the latest developments and validation results of a hybrid model which combines a broad-scale stochastic small-world network model with a macroscopic deterministic approach, to simulate the effects of large fires burning in heterogeneous landscapes. In the extended version of the model, vegetation is depicted as an amorphous network of combustible cells, and both radiation and convection from the flaming zone are considered in the preheating process of unburned cells. Examples are given to illustrate small-world effects and fire behavior near the percolation threshold. The model is applied to a Mediterranean fire that occurred in Corsica in 2009 showing a good agreement in terms of rate of spread, and area and shape of the burn. A study, based on a fractional factorial plan, is conducted to evaluate the influence of variations of model parameters on fire propagation.

  13. Cascaded Bragg scattering in fiber optics.

    Science.gov (United States)

    Xu, Y Q; Erkintalo, M; Genty, G; Murdoch, S G

    2013-01-15

    We report on a theoretical and experimental study of cascaded Bragg scattering in fiber optics. We show that the usual energy-momentum conservation of Bragg scattering can be considerably relaxed via cascade-induced phase-matching. Experimentally we demonstrate frequency translation over six- and 11-fold cascades, in excellent agreement with derived phase-matching conditions.

  14. Cascade redox flow battery systems

    Science.gov (United States)

    Horne, Craig R.; Kinoshita, Kim; Hickey, Darren B.; Sha, Jay E.; Bose, Deepak

    2014-07-22

    A reduction/oxidation ("redox") flow battery system includes a series of electrochemical cells arranged in a cascade, whereby liquid electrolyte reacts in a first electrochemical cell (or group of cells) before being directed into a second cell (or group of cells) where it reacts before being directed to subsequent cells. The cascade includes 2 to n stages, each stage having one or more electrochemical cells. During a charge reaction, electrolyte entering a first stage will have a lower state-of-charge than electrolyte entering the nth stage. In some embodiments, cell components and/or characteristics may be configured based on a state-of-charge of electrolytes expected at each cascade stage. Such engineered cascades provide redox flow battery systems with higher energy efficiency over a broader range of current density than prior art arrangements.

  15. Displacement cascades and defect annealing in tungsten, Part III: The sensitivity of cascade annealing in tungsten to the values of kinetic parameters

    Energy Technology Data Exchange (ETDEWEB)

    Nandipati, Giridhar; Setyawan, Wahyu; Heinisch, Howard L.; Roche, Kenneth J.; Kurtz, Richard J.; Wirth, Brian D.

    2015-07-01

    Object kinetic Monte Carlo (OKMC) simulations have been performed to investigate various aspects of cascade aging in bulk tungsten and to determine the sensitivity of the results to the kinetic parameters. The primary focus is on how the kinetic parameters affect the initial recombination of defects in the first few ns of a simulation. The simulations were carried out using the object kinetic Monte Carlo (OKMC) code KSOME (kinetic simulations of microstructure evolution), using a database of cascades obtained from results of molecular dynamics (MD) simulations at various primary knock-on atom (PKA) energies and directions at temperatures of 300, 1025 and 2050 K. The OKMC model was parameterized using defect migration barriers and binding energies from ab initio calculations. Results indicate that, due to the disparate mobilities of SIA and vacancy clusters in tungsten, annealing is dominated by SIA migration even at temperatures as high as 2050 K. For 100 keV cascades initiated at 300 K recombination is dominated by annihilation of large defect clusters. But for all other PKA energies and temperatures most of the recombination is due to the migration and rotation of small SIA clusters, while all the large SIA clusters escape the cubic simulation cell. The inverse U-shape behavior exhibited by the annealing efficiency as a function of temperature curve, especially for cascades of large PKA energies, is due to asymmetry in SIA and vacancy clustering assisted by the large difference in mobilities of SIAs and vacancies. This annealing behavior is unaffected by the dimensionality of SIA migration persists over a broad range of relative mobilities of SIAs and vacancies.

  16. Cascade of links in complex networks

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Yeqian; Sun, Bihui [Department of Management Science, School of Government, Beijing Normal University, 100875 Beijing (China); Zeng, An, E-mail: anzeng@bnu.edu.cn [School of Systems Science, Beijing Normal University, 100875 Beijing (China)

    2017-01-30

    Cascading failure is an important process which has been widely used to model catastrophic events such as blackouts and financial crisis in real systems. However, so far most of the studies in the literature focus on the cascading process on nodes, leaving the possibility of link cascade overlooked. In many real cases, the catastrophic events are actually formed by the successive disappearance of links. Examples exist in the financial systems where the firms and banks (i.e. nodes) still exist but many financial trades (i.e. links) are gone during the crisis, and the air transportation systems where the airports (i.e. nodes) are still functional but many airlines (i.e. links) stop operating during bad weather. In this letter, we develop a link cascade model in complex networks. With this model, we find that both artificial and real networks tend to collapse even if a few links are initially attacked. However, the link cascading process can be effectively terminated by setting a few strong nodes in the network which do not respond to any link reduction. Finally, a simulated annealing algorithm is used to optimize the location of these strong nodes, which significantly improves the robustness of the networks against the link cascade. - Highlights: • We propose a link cascade model in complex networks. • Both artificial and real networks tend to collapse even if a few links are initially attacked. • The link cascading process can be effectively terminated by setting a few strong nodes. • A simulated annealing algorithm is used to optimize the location of these strong nodes.

  17. Cascade of links in complex networks

    International Nuclear Information System (INIS)

    Feng, Yeqian; Sun, Bihui; Zeng, An

    2017-01-01

    Cascading failure is an important process which has been widely used to model catastrophic events such as blackouts and financial crisis in real systems. However, so far most of the studies in the literature focus on the cascading process on nodes, leaving the possibility of link cascade overlooked. In many real cases, the catastrophic events are actually formed by the successive disappearance of links. Examples exist in the financial systems where the firms and banks (i.e. nodes) still exist but many financial trades (i.e. links) are gone during the crisis, and the air transportation systems where the airports (i.e. nodes) are still functional but many airlines (i.e. links) stop operating during bad weather. In this letter, we develop a link cascade model in complex networks. With this model, we find that both artificial and real networks tend to collapse even if a few links are initially attacked. However, the link cascading process can be effectively terminated by setting a few strong nodes in the network which do not respond to any link reduction. Finally, a simulated annealing algorithm is used to optimize the location of these strong nodes, which significantly improves the robustness of the networks against the link cascade. - Highlights: • We propose a link cascade model in complex networks. • Both artificial and real networks tend to collapse even if a few links are initially attacked. • The link cascading process can be effectively terminated by setting a few strong nodes. • A simulated annealing algorithm is used to optimize the location of these strong nodes.

  18. Small-world networks exhibit pronounced intermittent synchronization

    Science.gov (United States)

    Choudhary, Anshul; Mitra, Chiranjit; Kohar, Vivek; Sinha, Sudeshna; Kurths, Jürgen

    2017-11-01

    We report the phenomenon of temporally intermittently synchronized and desynchronized dynamics in Watts-Strogatz networks of chaotic Rössler oscillators. We consider topologies for which the master stability function (MSF) predicts stable synchronized behaviour, as the rewiring probability (p) is tuned from 0 to 1. MSF essentially utilizes the largest non-zero Lyapunov exponent transversal to the synchronization manifold in making stability considerations, thereby ignoring the other Lyapunov exponents. However, for an N-node networked dynamical system, we observe that the difference in its Lyapunov spectra (corresponding to the N - 1 directions transversal to the synchronization manifold) is crucial and serves as an indicator of the presence of intermittently synchronized behaviour. In addition to the linear stability-based (MSF) analysis, we further provide global stability estimate in terms of the fraction of state-space volume shared by the intermittently synchronized state, as p is varied from 0 to 1. This fraction becomes appreciably large in the small-world regime, which is surprising, since this limit has been otherwise considered optimal for synchronized dynamics. Finally, we characterize the nature of the observed intermittency and its dominance in state-space as network rewiring probability (p) is varied.

  19. Disease spreading with epidemic alert on small-world networks

    International Nuclear Information System (INIS)

    Han, Xiao-Pu

    2007-01-01

    Base on two-dimension small-world networks, a susceptible-infected model with epidemic alert is proposed in this Letter. In this model, if some parts of the network are alarmed as dangerous, a fraction of edges between the alarmed parts and others will be removed, and two cases of alerting rules that the degree and frequency of contacts kept unchanged are considered respectively. The numerical simulations show that the spreading velocity is reduced by the accurate and timely epidemic alert, and the more accurate and timely, the stronger the deceleration effect. This model indicates that to broadcast epidemic alert timely is helpful and necessary in the control of epidemic spreading, and in agreement with the general view of epidemic alert. This work is helpful to understand the effects of epidemic alert on disease spreading

  20. Disrupted small world networks in patients without overt hepatic encephalopathy: A resting state fMRI study

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Long Jiang, E-mail: kevinzhlj@163.com [Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002 (China); Zheng, Gang [Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002 (China); College of Civil Aviation, Nanjing University of Aeronautics and Astronautics, Nanjing, Jiangsu 210016 (China); Zhang, Liping [College of Natural Science, Nanjing University of Aeronautics and Astronautics, Nanjing, Jiangsu 210016 (China); Zhong, Jianhui [Department of Biomedical Engineering, Zhejiang University, Hangzhou, Zhejiang 310027 (China); Li, Qiang [College of Natural Science, Nanjing University of Aeronautics and Astronautics, Nanjing, Jiangsu 210016 (China); Zhao, Tie Zhu [Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002 (China); College of Civil Aviation, Nanjing University of Aeronautics and Astronautics, Nanjing, Jiangsu 210016 (China); Lu, Guang Ming, E-mail: cjr.luguangming@vip.163.com [Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002 (China)

    2014-10-15

    Purpose: To explore changes in functional connectivity and topological organization of brain functional networks in cirrhotic patients with minimal hepatic encephalopathy (MHE) and non hepatic encephalopathy (nonHE) and their relationship with clinical markers. Materials and methods: Resting-state functional MR imaging was acquired in 22 MHE, 29 nonHE patients and 33 healthy controls. Functional connectivity networks were obtained by computing temporal correlations between any pairs of 90 cortical and subcortical regions. Graph analysis measures were quantitatively assessed for each subject. One-way analysis of covariance was applied to identify statistical differences of functional connectivity and network parameters among three groups. Correlations between clinical markers, such as Child–Pugh scores, venous blood ammonia level, and number connection test type A (NCT-A)/digit symbol test (DST) scores, and connectivity/graph metrics were calculated. Results: Thirty functional connectivities represented by edges were found to be abnormal (P < 0.05, FDR corrected) in cirrhotic patients, in which 16 edges (53.3%) were related with sub-cortical regions. MHE patients showed abnormal small-world attributes in the functional connectivity networks. Cirrhotic patients had significantly reduced nodal degree in 8 cortical regions and increased nodal centrality in 3 cortical regions. Twenty edges were correlated with either NCT-A or DST scores, in which 13 edges were related with sub-cortical regions. No correlation was found between Child–Pugh scores and graph theoretical measures in cirrhotic patients. Conclusion: Disturbances of brain functional connectivity and small world property loss are associated with neurocognitive impairment of cirrhotic patients. Reorganization of brain network occurred during disease progression from nonHE to MHE.

  1. Disrupted small world networks in patients without overt hepatic encephalopathy: A resting state fMRI study

    International Nuclear Information System (INIS)

    Zhang, Long Jiang; Zheng, Gang; Zhang, Liping; Zhong, Jianhui; Li, Qiang; Zhao, Tie Zhu; Lu, Guang Ming

    2014-01-01

    Purpose: To explore changes in functional connectivity and topological organization of brain functional networks in cirrhotic patients with minimal hepatic encephalopathy (MHE) and non hepatic encephalopathy (nonHE) and their relationship with clinical markers. Materials and methods: Resting-state functional MR imaging was acquired in 22 MHE, 29 nonHE patients and 33 healthy controls. Functional connectivity networks were obtained by computing temporal correlations between any pairs of 90 cortical and subcortical regions. Graph analysis measures were quantitatively assessed for each subject. One-way analysis of covariance was applied to identify statistical differences of functional connectivity and network parameters among three groups. Correlations between clinical markers, such as Child–Pugh scores, venous blood ammonia level, and number connection test type A (NCT-A)/digit symbol test (DST) scores, and connectivity/graph metrics were calculated. Results: Thirty functional connectivities represented by edges were found to be abnormal (P < 0.05, FDR corrected) in cirrhotic patients, in which 16 edges (53.3%) were related with sub-cortical regions. MHE patients showed abnormal small-world attributes in the functional connectivity networks. Cirrhotic patients had significantly reduced nodal degree in 8 cortical regions and increased nodal centrality in 3 cortical regions. Twenty edges were correlated with either NCT-A or DST scores, in which 13 edges were related with sub-cortical regions. No correlation was found between Child–Pugh scores and graph theoretical measures in cirrhotic patients. Conclusion: Disturbances of brain functional connectivity and small world property loss are associated with neurocognitive impairment of cirrhotic patients. Reorganization of brain network occurred during disease progression from nonHE to MHE

  2. Identifying a Small Molecule Blocking Antigen Presentation in Autoimmune Thyroiditis.

    Science.gov (United States)

    Li, Cheuk Wun; Menconi, Francesca; Osman, Roman; Mezei, Mihaly; Jacobson, Eric M; Concepcion, Erlinda; David, Chella S; Kastrinsky, David B; Ohlmeyer, Michael; Tomer, Yaron

    2016-02-19

    We previously showed that an HLA-DR variant containing arginine at position 74 of the DRβ1 chain (DRβ1-Arg74) is the specific HLA class II variant conferring risk for autoimmune thyroid diseases (AITD). We also identified 5 thyroglobulin (Tg) peptides that bound to DRβ1-Arg74. We hypothesized that blocking the binding of these peptides to DRβ1-Arg74 could block the continuous T-cell activation in thyroiditis needed to maintain the autoimmune response to the thyroid. The aim of the current study was to identify small molecules that can block T-cell activation by Tg peptides presented within DRβ1-Arg74 pockets. We screened a large and diverse library of compounds and identified one compound, cepharanthine that was able to block peptide binding to DRβ1-Arg74. We then showed that Tg.2098 is the dominant peptide when inducing experimental autoimmune thyroiditis (EAT) in NOD mice expressing human DRβ1-Arg74. Furthermore, cepharanthine blocked T-cell activation by thyroglobulin peptides, in particular Tg.2098 in mice that were induced with EAT. For the first time we identified a small molecule that can block Tg peptide binding and presentation to T-cells in autoimmune thyroiditis. If confirmed cepharanthine could potentially have a role in treating human AITD. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  3. Cascade Storage and Delivery System for a Multi Mission Space Exploration Vehicle (MMSEV)

    Science.gov (United States)

    Yagoda, Evan; Swickrath, Michael; Stambaugh, Imelda

    2012-01-01

    NASA is developing a Multi Mission Space Exploration Vehicle (MMSEV) for missions beyond Low Earth Orbit (LEO). The MMSEV is a pressurized vehicle used to extend the human exploration envelope for Lunar, Near Earth Object (NEO), and Deep Space missions. The Johnson Space Center is developing the Environmental Control and Life Support System (ECLSS) for the MMSEV. The MMSEV s intended use is to support longer sortie lengths with multiple Extra Vehicular Activities (EVAs) on a higher magnitude than any previous vehicle. This paper presents an analysis of a high pressure oxygen cascade storage and delivery system that will accommodate the crew during long duration Intra Vehicular Activity (IVA) and capable of multiple high pressure oxygen fills to the Portable Life Support System (PLSS) worn by the crew during EVAs. A cascade is a high pressure gas cylinder system used for the refilling of smaller compressed gas cylinders. Each of the large cylinders are filled by a compressor, but the cascade system allows small cylinders to be filled without the need of a compressor. In addition, the cascade system is useful as a "reservoir" to accommodate low pressure needs. A regression model was developed to provide the mechanism to size the cascade systems subject to constraints such as number of crew, extravehicular activity duration and frequency, and ullage gas requirements under contingency scenarios. The sizing routine employed a numerical integration scheme to determine gas compressibility changes during depressurization and compressibility effects were captured using the Soave-Redlich-Kwong (SRK) equation of state. A multi-dimensional nonlinear optimization routine was used to find the minimum cascade tank system mass that meets the mission requirements. The sizing algorithms developed in this analysis provide a powerful framework to assess cascade filling, compressor, and hybrid systems to design long duration vehicle ECLSS architecture. 1

  4. The comparison of extraction of energy in two-cascade and one-cascade targets

    Energy Technology Data Exchange (ETDEWEB)

    Dolgoleva, G. V., E-mail: dolgg@list.ru [National Research Tomsk State University, 36, Lenin Ave., 634050, Tomsk (Russian Federation); Ponomarev, I. V., E-mail: wingof17@mail.ru [Moscow State University, Department of Mechanics and Mathematics, 1, Vorobyovy Gory, Moscow,119961 (Russian Federation)

    2016-01-15

    The paper is devoted to numerical designing of cylindrical microtargets on the basis of shock-free compression. When designing microtargets for the controlled thermonuclear fusion, the core tasks are to select geometry and make-up of layers, and the law of energy embedding as well, which allow receiving of “burning” of deuterium- tritium mix, that is, the existence of thermonuclear reactions of working area. Yet, the energy yield as a result of thermonuclear reactions has to be more than the embedded energy (the coefficient of amplification is more than a unit). So, an important issue is the value of the embedded energy. The purpose of the present paper is to study the extraction of energy by working DT area in one-cascade and two-cascade targets. A bigger extraction of energy will contribute to a better burning of DT mix and a bigger energy yield as a result of thermonuclear reactions. The comparison of analytical results to numerical calculations is carried out. The received results show advantages of a two-cascade target compared to a one-cascade one.

  5. Synthesis of sp3-rich scaffolds for molecular libraries through complexity-generating cascade reactions

    DEFF Research Database (Denmark)

    Flagstad, Thomas; Min, Geanna; Bonnet, K.

    2016-01-01

    An efficient strategy for the synthesis of complex small molecules from simple building blocks is presented. Key steps of the strategy include tandem Petasis and Diels–Alder reactions, and divergent complexity-generating cyclization cascades from a key dialdehyde intermediate. The methodology...

  6. Experimental study of flow through compressor Cascade

    Directory of Open Access Journals (Sweden)

    Satyam Panchal

    2017-09-01

    Full Text Available The objective of this research work is to study the behaviour of flow at the inlet, within the blade passage and at the exit of a compressor cascade. For this purpose, a cascade with six numbers of aerofoil blades was designed and constructed. The cascade was fitted on the cascade test tunnel. Out of six blades two were instrumented for measuring the pressure distribution on the pressure and suction surface. The blades had a parabolic camber line, with a maximum camber position at 40% of the chord from the leading edge of the blade. The profile of the blade was C4, height of the blade was 160 mm, chord length was 80 mm, camber angle was 45° and stagger angle was 30°. Similarly, the length of the cascade was 300 mm, span was 160 mm, pitch was 60 mm, the actual chord of the cascade was 80 mm, the axial chord of the cascade was 70 mm, the stagger angle of the cascade was 30° and the pitch-chord ratio was 0.75. The data was taken and analyzed at −500% of the axial chord before the cascade, −25% of the axial chord before the leading edge, 25%, 50%, 75% and 150% of the axial chord from the leading edge of the blade. The readings were taken from the cascade wall to the mid span position along the pitch wise direction. The angle of incidence was also changed during the experiment and varied from i=−50°, −30°, −10° to 5°.

  7. Cascade-induced fluctuations and the transition from the stable to the critical cavity radius for swelling

    International Nuclear Information System (INIS)

    Hayns, M.R.; Mansur, L.K.

    1985-01-01

    Recently, a cascade diffusion theory was developed to understand cacade-induced fluctuations in point defect flux during irradiation. Application of the theory revealed that such fluctuations give rise to a mechanism of cascade-induced creep that is predicted to be of significant magnitude. Here we extend the investigation to the formation of cavities. Specifically, we explore the possible importance of cascade-induced cavity growth excursions in triggering a transition from the gas-content-dictated stable radius to the critical radius for bias-driven growth. Two methods of analysis are employed. The first uses the variance of fluctuations to assess the average effect of fluctuations. The second is based on the fact that in a large ensemble of cavities, a small fraction will experience larger than average excursions. This prospect is assessed by estimating upper limits to the processes. For the conditions considered, it is concluded that cascade-induced fluctuations are of minor importance in triggering the onset of swelling in a population of stable gas-containing cavities

  8. Retarded coordinates based at a world line and the motion of a small black hole in an external universe

    International Nuclear Information System (INIS)

    Poisson, Eric

    2004-01-01

    In the first part of this article I present a system of retarded coordinates based at an arbitrary world line of an arbitrary curved spacetime. The retarded-time coordinate labels forward light cones that are centered on the world line, the radial coordinate is an affine parameter on the null generators of these light cones, and the angular coordinates are constant on each of these generators. The spacetime metric in the retarded coordinates is displayed as an expansion in powers of the radial coordinate and expressed in terms of the world line's acceleration vector and the spacetime's Riemann tensor evaluated at the world line. The formalism is illustrated in two examples, the first involving a comoving world line of a spatially flat cosmology, the other featuring an observer in circular motion in the Schwarzschild spacetime. The main application of the formalism is presented in the second part of the article, in which I consider the motion of a small black hole in an empty external universe. I use the retarded coordinates to construct the metric of the small black hole perturbed by the tidal field of the external universe, and the metric of the external universe perturbed by the presence of the black hole. Matching these metrics produces the MiSaTaQuWa equations of motion for the small black hole

  9. Mechanisms for decoration of dislocations by small dislocation loops under cascade damage conditions

    DEFF Research Database (Denmark)

    Trinkaus, H.; Singh, B.N.; Foreman, A.J.E.

    1997-01-01

    . This effect may arise as a result of either (a) migration and enhanced agglomeration of single SIAs in the form of loops in the strain field of the dislocation or (b) glide and trapping of SIA loops (produced directly in the cascades) in the strain field of the dislocation, In the present paper, both...... of these possibilities are examined. It is shown that the strain field of the dislocation causes a SIA depletion in the compressive as well as in the dilatational region resulting in a reduced rather than enhanced agglomeration of SIAs. (SIA depletion may, however, induce enhanced vacancy agglomeration near dislocations...

  10. Simple, distance-dependent formulation of the Watts-Strogatz model for directed and undirected small-world networks

    Science.gov (United States)

    Song, H. Francis; Wang, Xiao-Jing

    2014-12-01

    Small-world networks—complex networks characterized by a combination of high clustering and short path lengths—are widely studied using the paradigmatic model of Watts and Strogatz (WS). Although the WS model is already quite minimal and intuitive, we describe an alternative formulation of the WS model in terms of a distance-dependent probability of connection that further simplifies, both practically and theoretically, the generation of directed and undirected WS-type small-world networks. In addition to highlighting an essential feature of the WS model that has previously been overlooked, namely the equivalence to a simple distance-dependent model, this alternative formulation makes it possible to derive exact expressions for quantities such as the degree and motif distributions and global clustering coefficient for both directed and undirected networks in terms of model parameters.

  11. Computer simulation of displacement cascades in copper

    International Nuclear Information System (INIS)

    Heinisch, H.L.

    1983-06-01

    More than 500 displacement cascades in copper have been generated with the computer simulation code MARLOWE over an energy range pertinent to both fission and fusion neutron spectra. Three-dimensional graphical depictions of selected cascades, as well as quantitative analysis of cascade shapes and sizes and defect densities, illustrate cascade behavior as a function of energy. With increasing energy, the transition from production of single compact damage regions to widely spaced multiple damage regions is clearly demonstrated

  12. Cascade Error Projection Learning Algorithm

    Science.gov (United States)

    Duong, T. A.; Stubberud, A. R.; Daud, T.

    1995-01-01

    A detailed mathematical analysis is presented for a new learning algorithm termed cascade error projection (CEP) and a general learning frame work. This frame work can be used to obtain the cascade correlation learning algorithm by choosing a particular set of parameters.

  13. Ultrarelativistic cascades and strangeness production

    International Nuclear Information System (INIS)

    Kahana, D.E.; Kahana, S.H.

    1998-02-01

    A two phase cascade, LUCIFER II, developed for the treatment of ultra high energy Ion-Ion collisions is applied to the production of strangeness at SPS energies. This simulation is able to simultaneously describe both hard processes such as Drell-Yan and slower, soft processes such as the production of light mesons by separating the dynamics into two steps, a fast cascade involving only the nucleons in the original colliding relativistic ions followed, after an appropriate delay, by a normal multiscattering of the resulting excited baryons and mesons produced virtually in the first step. No energy loss can take place in the short time interval over which the first cascade takes place. The chief result is a reconciliation of the important Drell-Yan measurements with the apparent success of standard cascades to describe the nucleon stopping and meson production in heavy ion experiments at the CERN SPS

  14. Critical features of coupling parameter in synchronization of small world neural networks

    International Nuclear Information System (INIS)

    Li Yanlong; Ma Jun; Xu Wenke; Li Hongbo; Wu Min

    2008-01-01

    The critical features of a coupling parameter in the synchronization of small world neural networks are investigated. A power law decay form is observed in this spatially extended system, the larger linked degree becomes, the larger critical coupling intensity. There exists maximal and minimal critical coupling intensity for synchronization in the extended system. An approximate synchronization diagram has been constructed. In the case of partial coupling, a primary result is presented about the critical coupling fraction for various linked degree of networks

  15. Order parameters and synchronization of FitzHugh–Nagumo small-world networks

    International Nuclear Information System (INIS)

    Yan-Long, Li; Jun, Ma; Yan-Jun, Liu; Wei, Zhang

    2009-01-01

    This paper numerically investigates the order parameter and synchronisation in the small world connected FitzHugh–Nagumo excitable systems. The simulations show that the order parameter continuously decreases with increasing D, the quality of the synchronisation worsens for large noise intensity. As the coupling intensity goes up, the quality of the synchronisation worsens, and it finds that the larger rewiring probability becomes the larger order parameter. It obtains the complete phase diagram for a wide range of values of noise intensity D and control parameter g. (cross-disciplinary physics and related areas of science and technology)

  16. Segregation of cascade induced interstitial loops at dislocations: possible effect on initiation of plastic deformation

    Energy Technology Data Exchange (ETDEWEB)

    Trinkaus, H. [Forschungszentrum Juelich GmbH (Germany). Inst. fuer Festkoerperforschung; Singh, B.N. [Materials Research Department, Risoe National Laboratory, DK-4000 Roskilde (Denmark); Foreman, A.J.E. [Materials Performance Department, Harwell Laboratory, Oxfordshire OX11 0RA (United Kingdom)

    1997-11-01

    In metals and alloys subjected to cascade damage dislocations are frequently found to be decorated with a high density of small clusters of self-interstitial atoms (SIAs) in the form of dislocation loops. In the present paper it is shown that this effect may be attributed to the glide and trapping of SIA loops, produced directly in cascades (rather than to the enhanced agglomeration of single SIAs), in the strain field of the dislocations. The conditions for the accumulation of glissile SIA loops near dislocations as well as the dose and temperature dependencies of this phenomenon are discussed. It is suggested that the decoration of dislocations with loops may play a key role in radiation hardening subjected to cascade damage. It is shown, for example, that the increase in the upper yield stress followed by a yield drop and plastic instability in metals andalloys subjected to cascade damage cannot be rationalized in terms of conventional dispersed barrier hardening (DBH) but may be understood in terms of cascade induced source hardening (CISH) in which the dislocations are considered to be locked by the loops decorating them. Estimates for the stress necessary to pull a dislocation away from its loop `cloud` are used to discuss the dose and temperature dependence of plastic flow initiation. (orig.). 55 refs.

  17. Segregation of cascade induced interstitial loops at dislocations: possible effect on initiation of plastic deformation

    International Nuclear Information System (INIS)

    Trinkaus, H.; Foreman, A.J.E.

    1997-01-01

    In metals and alloys subjected to cascade damage dislocations are frequently found to be decorated with a high density of small clusters of self-interstitial atoms (SIAs) in the form of dislocation loops. In the present paper it is shown that this effect may be attributed to the glide and trapping of SIA loops, produced directly in cascades (rather than to the enhanced agglomeration of single SIAs), in the strain field of the dislocations. The conditions for the accumulation of glissile SIA loops near dislocations as well as the dose and temperature dependencies of this phenomenon are discussed. It is suggested that the decoration of dislocations with loops may play a key role in radiation hardening subjected to cascade damage. It is shown, for example, that the increase in the upper yield stress followed by a yield drop and plastic instability in metals andalloys subjected to cascade damage cannot be rationalized in terms of conventional dispersed barrier hardening (DBH) but may be understood in terms of cascade induced source hardening (CISH) in which the dislocations are considered to be locked by the loops decorating them. Estimates for the stress necessary to pull a dislocation away from its loop 'cloud' are used to discuss the dose and temperature dependence of plastic flow initiation. (orig.)

  18. Binding energy effects in cascade evolution and sputtering

    International Nuclear Information System (INIS)

    Robinson, M.T.

    1995-06-01

    The MARLOWE model was extended to include a binding energy dependent on the local crystalline order, so that atoms are bound less strongly to their lattice sites near surfaces or associated damage. Sputtering and cascade evolution were studied on the examples of self-ion irradiations of Cu and Au monocrystals. In cascades, the mean binding energy is reduced ∼8% in Cu with little dependence on the initial recoil energy; in Au, it is reduced ∼9% at 1 keV and ∼15% at 100 keV. In sputtering, the mean binding energy is reduced ∼8% in Cu and ∼15% in Au with little energy dependence; the yields are increased about half as much. Most sites from which sputtered atoms originate are isolated in both metals. Small clusters of such sites occur in Cu, but there are some large clusters in Au, especially in [111] targets. There are always more large clusters with damage-dependent binding than with a constant binding energy, but only a few clusters are compact enough to be regarded as pits

  19. Inferring network structure from cascades

    Science.gov (United States)

    Ghonge, Sushrut; Vural, Dervis Can

    2017-07-01

    Many physical, biological, and social phenomena can be described by cascades taking place on a network. Often, the activity can be empirically observed, but not the underlying network of interactions. In this paper we offer three topological methods to infer the structure of any directed network given a set of cascade arrival times. Our formulas hold for a very general class of models where the activation probability of a node is a generic function of its degree and the number of its active neighbors. We report high success rates for synthetic and real networks, for several different cascade models.

  20. Non-small-bowel abnormalities identified during small bowel capsule endoscopy

    NARCIS (Netherlands)

    Hoedemakers, Reinier; Westerhof, Jessie; Weersma, Rinse K.; Koornstra, Jan J.

    2014-01-01

    AIM: To investigate the incidence of non-small-bowel abnormalities in patients referred for small bowel capsule endoscopy, this single center study was performed. METHODS: Small bowel capsule endoscopy is an accepted technique to investigate obscure gastrointestinal bleeding. This is defined as

  1. Astrophysical Gyrokinetics: Kinetic and Fluid Turbulent Cascades In Magentized Weakly Collisional Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Schekochihin, A. A.; Cowley, S. C.; Dorland, W.; Hammett, G. W.; Howes, G. G.; Quataert, E.; Tatsuno, T.

    2009-04-23

    This paper presents a theoretical framework for understanding plasma turbulence in astrophysical plasmas. It is motivated by observations of electromagnetic and density fluctuations in the solar wind, interstellar medium and galaxy clusters, as well as by models of particle heating in accretion disks. All of these plasmas and many others have turbulentmotions at weakly collisional and collisionless scales. The paper focuses on turbulence in a strong mean magnetic field. The key assumptions are that the turbulent fluctuations are small compared to the mean field, spatially anisotropic with respect to it and that their frequency is low compared to the ion cyclotron frequency. The turbulence is assumed to be forced at some system-specific outer scale. The energy injected at this scale has to be dissipated into heat, which ultimately cannot be accomplished without collisions. A kinetic cascade develops that brings the energy to collisional scales both in space and velocity. The nature of the kinetic cascade in various scale ranges depends on the physics of plasma fluctuations that exist there. There are four special scales that separate physically distinct regimes: the electron and ion gyroscales, the mean free path and the electron diffusion scale. In each of the scale ranges separated by these scales, the fully kinetic problem is systematically reduced to a more physically transparent and computationally tractable system of equations, which are derived in a rigorous way. In the "inertial range" above the ion gyroscale, the kinetic cascade separates into two parts: a cascade of Alfvenic fluctuations and a passive cascade of density and magnetic-fieldstrength fluctuations. The former are governed by the Reduced Magnetohydrodynamic (RMHD) equations at both the collisional and collisionless scales; the latter obey a linear kinetic equation along the (moving) field lines associated with the Alfvenic component (in the collisional limit, these compressive fluctuations

  2. Astrophysical Gyrokinetics: Kinetic and Fluid Turbulent Cascades In Magnetized Weakly Collisional Plasmas

    International Nuclear Information System (INIS)

    Schekochihin, A.A.; Cowley, S.C.; Dorland, W.; Hammett, G.W.; Howes, G.G.; Quataert, E.; Tatsuno, T.

    2009-01-01

    This paper presents a theoretical framework for understanding plasma turbulence in astrophysical plasmas. It is motivated by observations of electromagnetic and density fluctuations in the solar wind, interstellar medium and galaxy clusters, as well as by models of particle heating in accretion disks. All of these plasmas and many others have turbulent motions at weakly collisional and collisionless scales. The paper focuses on turbulence in a strong mean magnetic field. The key assumptions are that the turbulent fluctuations are small compared to the mean field, spatially anisotropic with respect to it and that their frequency is low compared to the ion cyclotron frequency. The turbulence is assumed to be forced at some system-specific outer scale. The energy injected at this scale has to be dissipated into heat, which ultimately cannot be accomplished without collisions. A kinetic cascade develops that brings the energy to collisional scales both in space and velocity. The nature of the kinetic cascade in various scale ranges depends on the physics of plasma fluctuations that exist there. There are four special scales that separate physically distinct regimes: the electron and ion gyroscales, the mean free path and the electron diffusion scale. In each of the scale ranges separated by these scales, the fully kinetic problem is systematically reduced to a more physically transparent and computationally tractable system of equations, which are derived in a rigorous way. In the 'inertial range' above the ion gyroscale, the kinetic cascade separates into two parts: a cascade of Alfvenic fluctuations and a passive cascade of density and magnetic-field strength fluctuations. The former are governed by the Reduced Magnetohydrodynamic (RMHD) equations at both the collisional and collisionless scales; the latter obey a linear kinetic equation along the (moving) field lines associated with the Alfvenic component (in the collisional limit, these compressive fluctuations

  3. Quasi-experiments to establish causal effects of HIV care and treatment and to improve the cascade of care

    OpenAIRE

    Bor, Jacob; Geldsetzer, Pascal; Venkataramani, Atheendar; B?rnighausen, Till

    2015-01-01

    Purpose of review Randomized, population-representative trials of clinical interventions are rare. Quasi-experiments have been used successfully to generate causal evidence on the cascade of HIV care in a broad range of real-world settings. Recent findings Quasi-experiments exploit exogenous, or quasi-random, variation occurring naturally in the world or because of an administrative rule or policy change to estimate causal effects. Well designed quasi-experiments have greater internal validit...

  4. Towards a conceptual framework for identifying student difficulties with solving Real-World Problems in Physics

    DEFF Research Database (Denmark)

    Niss, Martin

    2012-01-01

    This paper develops a conceptual framework for identifying the challenges and obstacles university students encounter when solving real-world problems involving Physics. The framework is based on viewing problem solving as a modelling process. In order to solve a real-world problem, the problem...... solver has to go through the steps and do the tasks of such a process. The paper presents a theoretical analysis of what it takes to solve three real-world problems, demonstrating how the framework presented captures the essential aspects of solving them. Moreover, it is argued that three steps critical...... for real-world problem solving – initial analysis of the problem situation, choice of relevant physical theory (the so-called paradigmatic choice) and mathematization – are not covered by existing models of problem solving in Physics. Finally, the existing research on student difficulties with problem...

  5. Abnormal cascading failure spreading on complex networks

    International Nuclear Information System (INIS)

    Wang, Jianwei; Sun, Enhui; Xu, Bo; Li, Peng; Ni, Chengzhang

    2016-01-01

    Applying the mechanism of the preferential selection of the flow destination, we develop a new method to quantify the initial load on an edge, of which the flow is transported along the path with the shortest edge weight between two nodes. Considering the node weight, we propose a cascading model on the edge and investigate cascading dynamics induced by the removal of the edge with the largest load. We perform simulated attacks on four types of constructed networks and two actual networks and observe an interesting and counterintuitive phenomenon of the cascading spreading, i.e., gradually improving the capacity of nodes does not lead to the monotonous increase in the robustness of these networks against cascading failures. The non monotonous behavior of cascading dynamics is well explained by the analysis on a simple graph. We additionally study the effect of the parameter of the node weight on cascading dynamics and evaluate the network robustness by a new metric.

  6. Gas separation performance of tapered cascade with membrane

    International Nuclear Information System (INIS)

    Ohno, Masayoshi; Morisue, Tetsuo; Ozaki, Osamu; Miyauchi, Terukatsu.

    1978-01-01

    Membrane gas separation cascades are analyzed at steady state. The method of calculating the flow rate and concentration profiles in the cascade are examined, using formulas expressing the various membrane separation cell characteristics. The method adopted is applicable to relatively high concentrations and separation factors. Considerations are further given on the steady state performance of four theoretical forms of cascade: (a) with common value of cut for all stages, (b) with symmetric separation cells, (c) with no mixing at the junction at each stage, and (d) ideal cascade. The analysis showed that, with membrane cells, the ideal cascade would have a pressure ratio varying from stage to stage. The symmetric separation cascade would provide a separation performance lower than the ideal cascade on account of the mixing at the junctions of streams possessing different concentrations, whereas the cut and separation factor of the no-mixing cascade requiring minimum membrane area exhibits zig-zag curves when plotted against stage number. Both these circumstances contribute to the lower separation performance obtained with these two forms as compared with the ideal cascade, and results in larger total membrane area; but these semi-ideal forms retain the advantage of easy practical treatment with their pressure ratio common to all stages. (auth.)

  7. Ultrarelativistic cascades and strangeness production

    Energy Technology Data Exchange (ETDEWEB)

    Kahana, D.E. [State Univ. of New York, Stony Brook, NY (United States). Dept. of Physics; Kahana, S.H. [Brookhaven National Lab., Upton, NY (United States). Physics Dept.

    1998-08-24

    A two-phase cascade code, LUCIFER II, developed for the treatment of ultra high energy-ion-ion collisions is applied to the production of strangeness at SPS energies {radical}(s)=17-20. This simulation is able to simultaneously describe both hard processes such as Drell-Yan and slower, soft processes such as the production of light mesons by separating the dynamics into two steps, a fast cascade involving only the nucleons in the original colliding relativistic ions followed, after an appropriate delay, by a normal multiscattering of the resulting excited baryons and mesons produced virtually in the first step. No energy loss can take place in the short time interval over which the first cascade takes place. The chief result is a reconciliation of the important Drell-Yan measurements with the apparent success of standard cascades to describe the nucleon stopping and meson production in heavy-ion experiments at the CERN SPS. (orig.) 26 refs.

  8. Ultrarelativistic cascades and strangeness production

    International Nuclear Information System (INIS)

    Kahana, D.E.; Kahana, S.H.

    1998-01-01

    A two-phase cascade code, LUCIFER II, developed for the treatment of ultra high energy-ion-ion collisions is applied to the production of strangeness at SPS energies √(s)=17-20. This simulation is able to simultaneously describe both hard processes such as Drell-Yan and slower, soft processes such as the production of light mesons by separating the dynamics into two steps, a fast cascade involving only the nucleons in the original colliding relativistic ions followed, after an appropriate delay, by a normal multiscattering of the resulting excited baryons and mesons produced virtually in the first step. No energy loss can take place in the short time interval over which the first cascade takes place. The chief result is a reconciliation of the important Drell-Yan measurements with the apparent success of standard cascades to describe the nucleon stopping and meson production in heavy-ion experiments at the CERN SPS. (orig.)

  9. MAPK cascades in guard cell signal transduction

    Directory of Open Access Journals (Sweden)

    Yuree eLee

    2016-02-01

    Full Text Available Guard cells form stomata on the epidermis and continuously respond to endogenous and environmental stimuli to fine-tune the gas exchange and transpirational water loss, processes which involve mitogen-activated protein kinase (MAPK cascades. MAPKs form three-tiered kinase cascades with MAPK kinases and MAPK kinase kinases, by which signals are transduced to the target proteins. MAPK cascade genes are highly conserved in all eukaryotes, and they play crucial roles in myriad developmental and physiological processes. MAPK cascades function during biotic and abiotic stress responses by linking extracellular signals received by receptors to cytosolic events and gene expression. In this review, we highlight recent findings and insights into MAPK-mediated guard cell signaling, including the specificity of MAPK cascades and the remaining questions.

  10. Volatile emissions from Cascade cinder cone eruptions: Implications for future hazard assessments in the Central and Southern Cascades

    Science.gov (United States)

    Walsh, L. K.; Wallace, P. J.; Cashman, K. V.

    2012-12-01

    the Central Oregon Cascades are (averages from each cone): 700-1190 ppm S; 480-1115 ppm Cl; 120-280 ppm F; and for Northern California: 620-1100 ppm S; 305-445 ppm Cl; 130-240 ppm F. Maximum values for the two regions are 1610 ppm S, 1490 ppm Cl, and 440 ppm F. The majority of studies on health hazards from inhalation or ingestion of volcanic aerosols are centered on livestock; therefore not much is known of the effects on humans. This emphasizes the importance of such a study in a volcanically active region. Levels of volcanic aerosols are considered "hazardous" and to "pose a hazardous risk" to surrounding agricultural and residential communities if concentrations are elevated above World Health Organization (WHO) or Occupational Safety and Health Administration maximum exposure limits (OSHA) (SO2: 7 ppm for a 24-hr period; HCl: 5 ppm for a 24-hr period; HF: 3 ppm for a 10-hr period). By assessing volatile concentrations from past eruptions we can better constrain the probable volatile hazards future cinder cone eruptions pose to surrounding agricultural and residential communities near the Cascades.

  11. World Gastroenterology Organization Practice Guidelines for the diagnosis and management of IBD in 2010

    DEFF Research Database (Denmark)

    Bernstein, Charles N; Fried, Michael; Krabshuis, J H

    2010-01-01

    have, in the past, been most evident in the developed world, their prevalence in the developing world has been gradually increasing in recent decades. This poses unique issues in diagnosis and management which have been scarcely addressed in the literature or in extant guidelines. Depending...... resources. The World Gastroenterology Organization has, accordingly, developed guidelines for diagnosing and treating IBD using a cascade approach to account for variability in resources in countries around the world....

  12. Growing Homophilic Networks Are Natural Navigable Small Worlds.

    Science.gov (United States)

    Malkov, Yury A; Ponomarenko, Alexander

    2016-01-01

    Navigability, an ability to find a logarithmically short path between elements using only local information, is one of the most fascinating properties of real-life networks. However, the exact mechanism responsible for the formation of navigation properties remained unknown. We show that navigability can be achieved by using only two ingredients present in the majority of networks: network growth and local homophily, giving a persuasive answer how the navigation appears in real-life networks. A very simple algorithm produces hierarchical self-similar optimally wired navigable small world networks with exponential degree distribution by using only local information. Adding preferential attachment produces a scale-free network which has shorter greedy paths, but worse (power law) scaling of the information extraction locality (algorithmic complexity of a search). Introducing saturation of the preferential attachment leads to truncated scale-free degree distribution that offers a good tradeoff between these parameters and can be useful for practical applications. Several features of the model are observed in real-life networks, in particular in the brain neural networks, supporting the earlier suggestions that they are navigable.

  13. Growing Homophilic Networks Are Natural Navigable Small Worlds.

    Directory of Open Access Journals (Sweden)

    Yury A Malkov

    Full Text Available Navigability, an ability to find a logarithmically short path between elements using only local information, is one of the most fascinating properties of real-life networks. However, the exact mechanism responsible for the formation of navigation properties remained unknown. We show that navigability can be achieved by using only two ingredients present in the majority of networks: network growth and local homophily, giving a persuasive answer how the navigation appears in real-life networks. A very simple algorithm produces hierarchical self-similar optimally wired navigable small world networks with exponential degree distribution by using only local information. Adding preferential attachment produces a scale-free network which has shorter greedy paths, but worse (power law scaling of the information extraction locality (algorithmic complexity of a search. Introducing saturation of the preferential attachment leads to truncated scale-free degree distribution that offers a good tradeoff between these parameters and can be useful for practical applications. Several features of the model are observed in real-life networks, in particular in the brain neural networks, supporting the earlier suggestions that they are navigable.

  14. RG cascades in hyperbolic quiver gauge theories

    International Nuclear Information System (INIS)

    Ahl Laamara, R.; Ait Ben Haddou, M.; Belhaj, A.; Drissi, L.B.; Saidi, E.H.

    2004-01-01

    In this paper, we provide a general classification of supersymmatric QFT4s into three basic sets: ordinary, affine and indefinite classes. The last class, which has not been enough explored in literature, is shown to share most of properties of ordinary and affine super-QFT4s. This includes, amongst others, its embedding in type II string on local Calabi-Yau threefolds. We give realizations of these supersymmetric QFT4s as D-brane world volume gauge theories. A special interest is devoted to hyperbolic subset for its peculiar features and for the role it plays in type IIB background with non-zero axion. We also study RG flows and duality cascades in case of hyperbolic quiver theories. Comments regarding the full indefinite sector are made

  15. Origin of unbalanced reaction of vacancies and interstitials during irradiation with cascades and influence on microstructural evolution

    International Nuclear Information System (INIS)

    Kiritani, M.; Yoshiie, T.; Kojima, S.; Satoh, Y.

    1993-01-01

    Based upon the underlying premise that all the microstructure evolution during irradiation results from the asymetrical reaction between vacancies and interstitials, the origin of the asymetry is sought and categorized, and the mechanism of defect structure evolution for each source of asymetry is investigated. The role of neutral sinks and the influence of dislocations are examined for the cases of irradiation with and without cascade damage. Vacancy cluster formation directly from cascades is found to favor the generation of freely migrating interstitials. Stochastic fluctuations of the point defect reactions under the balanced condition of vacancy and interstitial is experimentally detected, and the important role of the fluctuations is found in the determination of the fate of small interstitial cluster embryos produced by cascade damage. The influence of the unbalanced point defect reaction starting from difference in spacial distribution between vacancies and interstitials formed by cascade collisions is discussed as one of the important origins of vacancy dominant reactions. (orig.)

  16. Lack of plasma kallikrein-kinin system cascade in teleosts.

    Directory of Open Access Journals (Sweden)

    Marty Kwok-Shing Wong

    Full Text Available The kallikrein-kinin system (KKS consists of two major cascades in mammals: "plasma KKS" consisting of high molecular-weight (HMW kininogen (KNG, plasma kallikrein (KLKB1, and bradykinin (BK; and "tissue KKS" consisting of low molecular-weight (LMW KNG, tissue kallikreins (KLKs, and [Lys(0]-BK. Some components of the KKS have been identified in the fishes, but systematic analyses have not been performed, thus this study aims to define the KKS components in teleosts and pave a way for future physiological and evolutionary studies. Through a combination of genomics, molecular, and biochemical methods, we showed that the entire plasma KKS cascade is absent in teleosts. Instead of two KNGs as found in mammals, a single molecular weight KNG was found in various teleosts, which is homologous to the mammalian LMW KNG. Results of molecular phylogenetic and synteny analyses indicated that the all current teleost genomes lack KLKB1, and its unique protein structure, four apple domains and one trypsin domain, could not be identified in any genome or nucleotide databases. We identified some KLK-like proteins in teleost genomes by synteny and conserved domain analyses, which could be the orthologs of tetrapod KLKs. A radioimmunoassay system was established to measure the teleost BK and we found that [Arg(0]-BK is the major circulating form instead of BK, which supports that the teleost KKS is similar to the mammalian tissue KKS. Coincidently, coelacanths are the earliest vertebrate that possess both HMW KNG and KLKB1, which implies that the plasma KKS could have evolved in the early lobe-finned fish and descended to the tetrapod lineage. The co-evolution of HMW KNG and KLKB1 in lobe-finned fish and early tetrapods may mark the emergence of the plasma KKS and a contact activation system in blood coagulation, while teleosts may have retained a single KKS cascade.

  17. Defect accumulation under cascade damage conditions

    DEFF Research Database (Denmark)

    Trinkaus, H.; Singh, B.N.; Woo, C.H.

    1994-01-01

    in terms of this reaction kinetics taking into account cluster production, dissociation, migration and annihilation at extended sinks. Microstructural features which are characteristic of cascade damage and cannot be explained in terms of the conventional single defect reaction kinetics are emphasized......There is now ample evidence from both experimental and computer simulation studies that in displacement cascades not only intense recombination takes place but also efficient clustering of both self-interstitial atoms (SIAs) and vacancies. The size distributions of the two types of defects produced...... reactions kinetics associated with the specific features of cascade damage is described, with emphasis on asymmetries between SIA and vacancy type defects concerning their production, stability, mobility and interactions with other defects. Defect accumulation under cascade damage conditions is discussed...

  18. Maturation processes and structures of small secreted peptides in plants

    Directory of Open Access Journals (Sweden)

    Ryo eTabata

    2014-07-01

    Full Text Available In the past decade, small secreted peptides have proven to be essential for various aspects of plant growth and development, including the maintenance of certain stem cell populations. Most small secreted peptides identified in plants to date are recognised by membrane-localized receptor kinases, the largest family of receptor proteins in the plant genome. This peptide-receptor interaction is essential for initiating intracellular signalling cascades. Small secreted peptides often undergo post-translational modifications and proteolytic processing to generate the mature peptides. Recent studies suggest that, in contrast to the situation in mammals, the proteolytic processing of plant peptides involves a number of complex steps. Furthermore, NMR-based structural analysis demonstrated that post-translational modifications induce the conformational changes needed for full activity. In this mini review, we summarise recent advances in our understanding of how small secreted peptides are modified and processed into biologically active peptides and describe the mature structures of small secreted peptides in plants.

  19. Effects of indirect bandgap top cells in a monolithic cascade cell structure

    Science.gov (United States)

    Curtis, H. B.; Godlewski, M. P.

    1982-01-01

    The effect of having a slightly indirect top cell in a three junction cascade monolithic stack is calculated. The minority carrier continuity equations are utilized to calculate individual junction performance. Absorption coefficient curves for general III-V compounds are calculated for a variety of direct and indirect gap materials. The results indicate that for a small excursion into the indirect region, (about 0.1 eV), the loss of efficiency is acceptably small (less than 2.5 percent) and considerably less than attempting to make the top junction a smaller direct bandgap.

  20. Cascade Error Projection: An Efficient Hardware Learning Algorithm

    Science.gov (United States)

    Duong, T. A.

    1995-01-01

    A new learning algorithm termed cascade error projection (CEP) is presented. CEP is an adaption of a constructive architecture from cascade correlation and the dynamical stepsize of A/D conversion from the cascade back propagation algorithm.

  1. Cascade production of Ar(3p54p) following electron bombardment

    International Nuclear Information System (INIS)

    Keto, J.W.; Kuo, C.

    1981-01-01

    We observe the time dependence of the fluorescence of Ar(3p 5 4p) following electron excitation of argon at pressures from 2--3000 Torr. The population of these levels at the lowest pressures observed is dominated by radiative cascade from Ar(3p 5 3d) and Ar(3p 5 5s). For argon states 4p'[1/2] 0 , 4p'[3/2] 2 , and 4p[1/2] 0 we find the cascade transitions can be identified and we assign radiative lifetimes of 61 +- 10, 69 +- 12, and 61 +- 6 nsec to 3d'[3/2] 1 , 3d'[5/2] 3 , and 3d[3/2] 1 , respectively. For cascade lifetimes to other levels, unique assignments cannot be made until values for forbidden electron impact cross sections to 3p 5 3d and 3p 5 5s can be obtained. The collisional quenching rates for the cascading levels are measured and found to explain the pressure dependence of the decay of Ar(3p 5 4p) over the full range of pressure except for Ar(3p 5 4p'[1/2] 1 ) which has a unique and interesting behavior at high pressures

  2. Noise propagation in two-step series MAPK cascade.

    Directory of Open Access Journals (Sweden)

    Venkata Dhananjaneyulu

    Full Text Available Series MAPK enzymatic cascades, ubiquitously found in signaling networks, act as signal amplifiers and play a key role in processing information during signal transduction in cells. In activated cascades, cell-to-cell variability or noise is bound to occur and thereby strongly affects the cellular response. Commonly used linearization method (LM applied to Langevin type stochastic model of the MAPK cascade fails to accurately predict intrinsic noise propagation in the cascade. We prove this by using extensive stochastic simulations for various ranges of biochemical parameters. This failure is due to the fact that the LM ignores the nonlinear effects on the noise. However, LM provides a good estimate of the extrinsic noise propagation. We show that the correct estimate of intrinsic noise propagation in signaling networks that contain at least one enzymatic step can be obtained only through stochastic simulations. Noise propagation in the cascade depends on the underlying biochemical parameters which are often unavailable. Based on a combination of global sensitivity analysis (GSA and stochastic simulations, we developed a systematic methodology to characterize noise propagation in the cascade. GSA predicts that noise propagation in MAPK cascade is sensitive to the total number of upstream enzyme molecules and the total number of molecules of the two substrates involved in the cascade. We argue that the general systematic approach proposed and demonstrated on MAPK cascade must accompany noise propagation studies in biological networks.

  3. Method of fault diagnosis in nozzle cascades for U-235 enrichment

    International Nuclear Information System (INIS)

    Schuette, R.; Steinhaus, H.

    1978-09-01

    In a separation nozzle cascade for enrichment of the light uranium isotope U-235 some 450 stages are connected in series. For optimum separation performance of such a plant the design values of the nozzle inlet pressure, of the UF 6 concentration of the UF 6 -cut and the cut of the light additional gas must be matched in all separation stages. Also the feed stream, the product stream, and the tails stream have to be controlled according to the cascade design values. Since it is not possible to measure the cuts directly, these values are calculated on the basis of the material flow balances of the cascade using the pressure values and the UF 6 concentration measurements in each stage, these data being supplemented by concentration measurements in the light and heavy fractions of selected stages. This approach requires the use of a digital computer for processing some 1500 readings to calculate the 2500 plant parameters defining the plant state. This study describes a method of diagnosing the major faults to be expected in a separation nozzle cascade. It is based on the fact that the fault profiles are characterized sufficiently well by maximum values and values to identify the cause of a fault and localize the point where it occurs by means of simple relations between these six values and of their relative positions. The performance of the method has been tested in experiments in the ten-stage pilot plant. For use in commercial separation nozzle cascades the range of performance and the special mode of implementation can be derived from the characteristics of the plant components (separation nozzles, compressors, control valves). The methodological approach in this fault diagnosis also provides the basis for computer aided control procedures to raise a separation cascade from any steady plant condition to its set point operation. (orig./HP) 891 HP [de

  4. Optimal convergence in naming game with geography-based negotiation on small-world networks

    Energy Technology Data Exchange (ETDEWEB)

    Liu Runran, E-mail: runran@mail.ustc.edu.c [Department of Modern Physics and Nonlinear Science Center, University of Science and Technology of China, Hefei Anhui 230026 (China); Wang Wenxu [School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85287 (United States); Lai Yingcheng [School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85287 (United States); Department of Physics, Arizona State University, Tempe, AZ 85287 (United States); Chen Guanrong [Department of Electronic Engineering, City University of Hong Kong, Hong Kong (Hong Kong); Wang Binghong [Department of Modern Physics and Nonlinear Science Center, University of Science and Technology of China, Hefei Anhui 230026 (China); Research Center for Complex System Science, University of Shanghai for Science and Technology and Shanghai Academy of System Science, Shanghai 200093 (China)

    2011-01-17

    We propose a negotiation strategy to address the effect of geography on the dynamics of naming games over small-world networks. Communication and negotiation frequencies between two agents are determined by their geographical distance in terms of a parameter characterizing the correlation between interaction strength and the distance. A finding is that there exists an optimal parameter value leading to fastest convergence to global consensus on naming. Numerical computations and a theoretical analysis are provided to substantiate our findings.

  5. Optimal convergence in naming game with geography-based negotiation on small-world networks

    International Nuclear Information System (INIS)

    Liu Runran; Wang Wenxu; Lai Yingcheng; Chen Guanrong; Wang Binghong

    2011-01-01

    We propose a negotiation strategy to address the effect of geography on the dynamics of naming games over small-world networks. Communication and negotiation frequencies between two agents are determined by their geographical distance in terms of a parameter characterizing the correlation between interaction strength and the distance. A finding is that there exists an optimal parameter value leading to fastest convergence to global consensus on naming. Numerical computations and a theoretical analysis are provided to substantiate our findings.

  6. Assessment on tracking error performance of Cascade P/PI, NPID and N-Cascade controller for precise positioning of xy table ballscrew drive system

    International Nuclear Information System (INIS)

    Abdullah, L; Jamaludin, Z; Rafan, N A; Jamaludin, J; Chiew, T H

    2013-01-01

    At present, positioning plants in machine tools are looking for high degree of accuracy and robustness attributes for the purpose of compensating various disturbance forces. The objective of this paper is to assess the tracking performance of Cascade P/PI, Nonlinear PID (NPID) and Nonlinear cascade (N-Cascade) controller with the existence of disturbance forces in the form of cutting forces. Cutting force characteristics at different cutting parameters; such as spindle speed rotations is analysed using Fast Fourier Transform. The tracking performance of a Nonlinear cascade controller in presence of these cutting forces is compared with NPID controller and Cascade P/PI controller. Robustness of these controllers in compensating different cutting characteristics is compared based on reduction in the amplitudes of cutting force harmonics using Fast Fourier Transform. It is found that the N-cascade controller performs better than both NPID controller and Cascade P/PI controller. The average percentage error reduction between N-cascade controller and Cascade P/PI controller is about 65% whereas the average percentage error reduction between cascade controller and NPID controller is about 82% at spindle speed of 3000 rpm spindle speed rotation. The finalized design of N-cascade controller could be utilized further for machining application such as milling process. The implementation of N-cascade in machine tools applications will increase the quality of the end product and the productivity in industry by saving the machining time. It is suggested that the range of the spindle speed could be made wider to accommodate the needs for high speed machining

  7. Complex Behavior in an Integrate-and-Fire Neuron Model Based on Small World Networks

    International Nuclear Information System (INIS)

    Lin Min; Chen Tianlun

    2005-01-01

    Based on our previously pulse-coupled integrate-and-fire neuron model in small world networks, we investigate the complex behavior of electroencephalographic (EEG)-like activities produced by such a model. We find EEG-like activities have obvious chaotic characteristics. We also analyze the complex behaviors of EEG-like signals, such as spectral analysis, reconstruction of the phase space, the correlation dimension, and so on.

  8. Time structure of cascade showers

    International Nuclear Information System (INIS)

    Nakatsuka, Takao

    1984-01-01

    Interesting results have been reported on the time structure of the electromagnetic components of air showers which have been obtained by using recent fast electronic circuit technology. However, these analyses and explanations seem not very persuasive. One of the reasons is that there is not satisfactory theoretical calculation yet to explain the delay of electromagnetic components in cascade processes which are the object of direct observation. Therefore, Monte Carlo calculation was attempted for examining the relationship between the altitude at which high energy γ-ray is generated up in the air and the time structure of cascade showers at the level of observation. The investigation of a dominant factor over the delay of electromagnetic components indicated that the delay due to the multiple scattering of electrons was essential. The author used the analytical solution found by himself of C. N. Yang's equation for the study on the delay due to multiple scattering. The results were as follows: The average delay time and the spread of distribution of electromagnetic cascades were approximately in linear relationship with the mass of a material having passed in a thin uniform medium; the rise time of arrival time distribution for electromagnetic cascade showers was very steep under the condition that they were generated up in the air and observed on the ground; the subpeaks delayed by tens of ns in arrival time may sometimes appear due to the perturbation in electromagnetic cascade processes. (Wakatsuki, Y.)

  9. Transmission of severe acute respiratory syndrome in dynamical small-world networks

    Science.gov (United States)

    Masuda, Naoki; Konno, Norio; Aihara, Kazuyuki

    2004-03-01

    The outbreak of severe acute respiratory syndrome (SARS) is still threatening the world because of a possible resurgence. In the current situation that effective medical treatments such as antiviral drugs are not discovered yet, dynamical features of the epidemics should be clarified for establishing strategies for tracing, quarantine, isolation, and regulating social behavior of the public at appropriate costs. Here we propose a network model for SARS epidemics and discuss why superspreaders emerged and why SARS spread especially in hospitals, which were key factors of the recent outbreak. We suggest that superspreaders are biologically contagious patients, and they may amplify the spreads by going to potentially contagious places such as hospitals. To avoid mass transmission in hospitals, it may be a good measure to treat suspected cases without hospitalizing them. Finally, we indicate that SARS probably propagates in small-world networks associated with human contacts and that the biological nature of individuals and social group properties are factors more important than the heterogeneous rates of social contacts among individuals. This is in marked contrast with epidemics of sexually transmitted diseases or computer viruses to which scale-free network models often apply.

  10. Phase synchronization on small-world networks with community structure

    International Nuclear Information System (INIS)

    Xiao-Hua, Wang; Li-Cheng, Jiao; Jian-She, Wu

    2010-01-01

    In this paper, we propose a simple model that can generate small-world network with community structure. The network is introduced as a tunable community organization with parameter r, which is directly measured by the ratio of inter- to intra-community connectivity, and a smaller r corresponds to a stronger community structure. The structure properties, including the degree distribution, clustering, the communication efficiency and modularity are also analysed for the network. In addition, by using the Kuramoto model, we investigated the phase synchronization on this network, and found that increasing the fuzziness of community structure will markedly enhance the network synchronizability; however, in an abnormal region (r ≤ 0.001), the network has even worse synchronizability than the case of isolated communities (r = 0). Furthermore, this network exhibits a remarkable synchronization behaviour in topological scales: the oscillators of high densely interconnected communities synchronize more easily, and more rapidly than the whole network. (general)

  11. Mapping Koch curves into scale-free small-world networks

    International Nuclear Information System (INIS)

    Zhang Zhongzhi; Gao Shuyang; Zhou Shuigeng; Chen Lichao; Zhang Hongjuan; Guan Jihong

    2010-01-01

    The class of Koch fractals is one of the most interesting families of fractals, and the study of complex networks is a central issue in the scientific community. In this paper, inspired by the famous Koch fractals, we propose a mapping technique converting Koch fractals into a family of deterministic networks called Koch networks. This novel class of networks incorporates some key properties characterizing a majority of real-life networked systems-a power-law distribution with exponent in the range between 2 and 3, a high clustering coefficient, a small diameter and average path length and degree correlations. Besides, we enumerate the exact numbers of spanning trees, spanning forests and connected spanning subgraphs in the networks. All these features are obtained exactly according to the proposed generation algorithm of the networks considered. The network representation approach could be used to investigate the complexity of some real-world systems from the perspective of complex networks.

  12. Multiple Linear Regression for Reconstruction of Gene Regulatory Networks in Solving Cascade Error Problems.

    Science.gov (United States)

    Salleh, Faridah Hani Mohamed; Zainudin, Suhaila; Arif, Shereena M

    2017-01-01

    Gene regulatory network (GRN) reconstruction is the process of identifying regulatory gene interactions from experimental data through computational analysis. One of the main reasons for the reduced performance of previous GRN methods had been inaccurate prediction of cascade motifs. Cascade error is defined as the wrong prediction of cascade motifs, where an indirect interaction is misinterpreted as a direct interaction. Despite the active research on various GRN prediction methods, the discussion on specific methods to solve problems related to cascade errors is still lacking. In fact, the experiments conducted by the past studies were not specifically geared towards proving the ability of GRN prediction methods in avoiding the occurrences of cascade errors. Hence, this research aims to propose Multiple Linear Regression (MLR) to infer GRN from gene expression data and to avoid wrongly inferring of an indirect interaction (A → B → C) as a direct interaction (A → C). Since the number of observations of the real experiment datasets was far less than the number of predictors, some predictors were eliminated by extracting the random subnetworks from global interaction networks via an established extraction method. In addition, the experiment was extended to assess the effectiveness of MLR in dealing with cascade error by using a novel experimental procedure that had been proposed in this work. The experiment revealed that the number of cascade errors had been very minimal. Apart from that, the Belsley collinearity test proved that multicollinearity did affect the datasets used in this experiment greatly. All the tested subnetworks obtained satisfactory results, with AUROC values above 0.5.

  13. Simulation of novel intensity modulated cascaded coated LPFG sensor based on PMTP

    Science.gov (United States)

    Feng, Wenbin; Gu, Zhengtian; Lin, Qiang; Sang, Jiangang

    2017-12-01

    This paper presents a novel intensity modulated cascaded long-period fiber grating (CLPFG) sensor which is cascaded by two same coated long-period fiber gratings (LPFGs) operating at the phase-matching turning point (PMTP). The sensor combines the high sensitivity of LPFG operating at PMTP and the narrow bandwidth of interference attenuation band of CLPFG, so a higher response to small change of the surrounding refractive index (SRI) can be obtained by intensity modulation. Based on the coupled-mode theory, the grating parameters of the PMTP of a middle odd order cladding mode of a single LPFG are calculated. Then this two same LPFGs are cascaded into a CLPFG, and the optical transmission spectrum of the CLPFG is calculated by transfer matrix method. A resonant wavelength of a special interference attenuation band whose intensity has the highest response to SRI, is selected form CLPFG’s spectrum, and setting the resonant wavelength as the operating wavelength of the sensor. Furthermore, the simulation results show that the resolution of SRI of this CLPFG is available to 1.97 × 10-9 by optimizing the film optical parameters, which is about three orders of magnitude higher than coated dual-peak LPFG and cascaded LPFG sensors. It is noteworthy that the sensor is also sensitive to the refractive index of coat, so that the sensor is expected to be applied to detections of gas, PH value, humidity and so on, in the future.

  14. Formalism of continual integrals for cascade processes with particle fusion

    International Nuclear Information System (INIS)

    Gedalin, Eh.V.

    1987-01-01

    Formalism of continuous integrals for description of cascade processes, in which besides cascade particle reproduction, their synthesis and coalescence take place, is used. Account of cascade particle coalescence leads to the fact that the development of some cascade branches cannot be independent and main equations of the cascade process become functional instead of integral. The method of continuous intagrals permits to construct in the closed form producing functionals for the cascade process and to obtain the rules of their calculation using diagrams. Analytical expressions in the form of continuous integrals for producing functionals describing cascade development are obtained

  15. Energetic particle parallel diffusion in a cascading wave turbulence in the foreshock region

    Directory of Open Access Journals (Sweden)

    F. Otsuka

    2007-09-01

    Full Text Available We study parallel (field-aligned diffusion of energetic particles in the upstream of the bow shock with test particle simulations. We assume parallel shock geometry of the bow shock, and that MHD wave turbulence convected by the solar wind toward the shock is purely transverse in one-dimensional system with a constant background magnetic field. We use three turbulence models: a homogeneous turbulence, a regular cascade from a large scale to smaller scales, and an inverse cascade from a small scale to larger scales. For the homogeneous model the particle motions along the average field are Brownian motions due to random and isotropic scattering across 90 degree pitch angle. On the other hand, for the two cascade models particle motion is non-Brownian due to coherent and anisotropic pitch angle scattering for finite time scale. The mean free path λ|| calculated by the ensemble average of these particle motions exhibits dependence on the distance from the shock. It also depends on the parameters such as the thermal velocity of the particles, solar wind flow velocity, and a wave turbulence model. For the inverse cascade model, the dependence of λ|| at the shock on the thermal energy is consistent with the hybrid simulation done by Giacalone (2004, but the spatial dependence of λ|| is inconsistent with it.

  16. Cascaded Amplitude Modulations in Sound Texture Perception

    DEFF Research Database (Denmark)

    McWalter, Richard Ian; Dau, Torsten

    2017-01-01

    . In this study, we investigated the perception of sound textures that contain rhythmic structure, specifically second-order amplitude modulations that arise from the interaction of different modulation rates, previously described as "beating" in the envelope-frequency domain. We developed an auditory texture...... model that utilizes a cascade of modulation filterbanks that capture the structure of simple rhythmic patterns. The model was examined in a series of psychophysical listening experiments using synthetic sound textures-stimuli generated using time-averaged statistics measured from real-world textures....... In a texture identification task, our results indicated that second-order amplitude modulation sensitivity enhanced recognition. Next, we examined the contribution of the second-order modulation analysis in a preference task, where the proposed auditory texture model was preferred over a range of model...

  17. Cascade of kinetic energy and scalar variance in DC electrokinetic turbulence

    Science.gov (United States)

    Zhao, Wei; Wang, Guiren

    2017-11-01

    Turbulent flow can be generated by DC electrokinetic (EK) force based on the electric conductivity and permittivity variations in fluids, as have been demonstrated by Varshney et al (2016), where a -1.4 slope of velocity power spectrum is observed. Here, we theoretically found the scaling exponents of velocity and scalar structures in the electric-body-force (EBF) dominant subregion of DC EK turbulence were 2/5 (equivalent to the -7/5 slope of velocity power spectrum) and 4/5 respectively. The theory perfectly explains the experimental results of Varshney et al. (2016). Based on Kármán-Howarth equation with forcing terms, the energy cascade process of DC EK turbulence was also investigated. Depending on the electric Rayleigh number (Rae) , two different energy cascade processes may happen. When Rae is small, the kinetic energy cascades along inertial subregion and EBF dominant subregion in sequence, before it is dissipated by fluid viscosity. When Rae is sufficiently large, the inertial subregion may be absent with EBF dominant subregion left. This investigation is very important on understand EK turbulence, which could be widely existed in nature and applied in engineerings. The work was supported by NSFC (11672229), and NSF (CAREER CBET-0954977 and MRI CBET-1040227).

  18. MassCascade: Visual Programming for LC-MS Data Processing in Metabolomics.

    Science.gov (United States)

    Beisken, Stephan; Earll, Mark; Portwood, David; Seymour, Mark; Steinbeck, Christoph

    2014-04-01

    Liquid chromatography coupled to mass spectrometry (LC-MS) is commonly applied to investigate the small molecule complement of organisms. Several software tools are typically joined in custom pipelines to semi-automatically process and analyse the resulting data. General workflow environments like the Konstanz Information Miner (KNIME) offer the potential of an all-in-one solution to process LC-MS data by allowing easy integration of different tools and scripts. We describe MassCascade and its workflow plug-in for processing LC-MS data. The Java library integrates frequently used algorithms in a modular fashion, thus enabling it to serve as back-end for graphical front-ends. The functions available in MassCascade have been encapsulated in a plug-in for the workflow environment KNIME, allowing combined use with e.g. statistical workflow nodes from other providers and making the tool intuitive to use without knowledge of programming. The design of the software guarantees a high level of modularity where processing functions can be quickly replaced or concatenated. MassCascade is an open-source library for LC-MS data processing in metabolomics. It embraces the concept of visual programming through its KNIME plug-in, simplifying the process of building complex workflows. The library was validated using open data.

  19. Impact of Partial Time Delay on Temporal Dynamics of Watts-Strogatz Small-World Neuronal Networks

    Science.gov (United States)

    Yan, Hao; Sun, Xiaojuan

    2017-06-01

    In this paper, we mainly discuss effects of partial time delay on temporal dynamics of Watts-Strogatz (WS) small-world neuronal networks by controlling two parameters. One is the time delay τ and the other is the probability of partial time delay pdelay. Temporal dynamics of WS small-world neuronal networks are discussed with the aid of temporal coherence and mean firing rate. With the obtained simulation results, it is revealed that for small time delay τ, the probability pdelay could weaken temporal coherence and increase mean firing rate of neuronal networks, which indicates that it could improve neuronal firings of the neuronal networks while destroying firing regularity. For large time delay τ, temporal coherence and mean firing rate do not have great changes with respect to pdelay. Time delay τ always has great influence on both temporal coherence and mean firing rate no matter what is the value of pdelay. Moreover, with the analysis of spike trains and histograms of interspike intervals of neurons inside neuronal networks, it is found that the effects of partial time delays on temporal coherence and mean firing rate could be the result of locking between the period of neuronal firing activities and the value of time delay τ. In brief, partial time delay could have great influence on temporal dynamics of the neuronal networks.

  20. Cost intensity of identifying contraindications to driving a company car through psychological tests on the basis of real-world data in Poland.

    Science.gov (United States)

    Juszczyk, Grzegorz; Czerw, Aleksandra; Tatara, Tomasz; Duda-Zalewska, Aneta; Walusiak-Skorupa, Joanna; Słoniewski, Robert; Staniszewska, Anna; Olejniczak, Dominik; Religioni, Urszula

    2017-12-01

    The study objective was to determine the cost intensity of identifying contraindications to fleet car driving in preventive care. The objective of a psychological examination is to identify impaired psychomotor function as well as any intellectual, cognitive or emotional incapacities, which may seriously impede safety. Real-world data were collected from the healthcare provider in Poland. A total of 8111 anonymous records from psychomotor tests performed between January 1 and December 31, 2012 were analysed. The number needed to screen to identify one person with contraindications to driving was 737. An individual examination costs PLN 150, thus the estimated cost of identifying one case was PLN 110,550 (EUR 25,000). The average number of tests in a small enterprise with 20-50 fleet cars was estimated at 5-25 in a 5-year period and their cost at PLN 3750 (PLN 750 annually). Health check-ups include ophthalmological and neurological consultations; therefore, psychological examination of fleet car drivers may be considered excessive due to cost and limited preventive value. High costs may be burdensome mainly to larger companies. A final decision regarding necessity of psychological testing should be preceded by medical assessment of the risk of work accidents.

  1. Exploring Geology on the World-Wide Web--Volcanoes and Volcanism.

    Science.gov (United States)

    Schimmrich, Steven Henry; Gore, Pamela J. W.

    1996-01-01

    Focuses on sites on the World Wide Web that offer information about volcanoes. Web sites are classified into areas of Global Volcano Information, Volcanoes in Hawaii, Volcanoes in Alaska, Volcanoes in the Cascades, European and Icelandic Volcanoes, Extraterrestrial Volcanism, Volcanic Ash and Weather, and Volcano Resource Directories. Suggestions…

  2. A small-world methodology of analysis of interchange energy-networks: The European behaviour in the economical crisis

    International Nuclear Information System (INIS)

    Dassisti, M.; Carnimeo, L.

    2013-01-01

    European energy policy pursues the objective of a sustainable, competitive and reliable supply of energy. In 2007, the European Commission adopted a proper energy policy for Europe supported by several documents and included an action plan to meet the major energy challenges Europe has to face. A farsighted diversified yearly mix of energies was suggested to countries, aiming at increasing security of supply and efficiency, but a wide and systemic view of energy interchanges between states was missing. In this paper, a Small-World methodology of analysis of Interchange Energy-Networks (IENs) is presented, with the aim of providing a useful tool for planning sustainable energy policies. A proof case is presented to validate the methodology by considering the European IEN behaviour in the period of economical crisis. This network is approached as a Small World Net from a modelling point of view, by supposing that connections between States are characterised by a probability value depending on economic/political relations between countries. - Highlights: • Different view of the imports and exports of electric energy flows between European for potential use in ruling exchanges. • Panel data from 1996 to 2010 as part of a network of exchanges was considered from Eurostat official database. • The European import/export energy flows modelled as a network with Small World phenomena, interpreting the evolution over the years. • Interesting systemic tool for ruling and governing energy flows between countries

  3. Impact of small-world network topology on the conventional artificial neural network for the diagnosis of diabetes

    International Nuclear Information System (INIS)

    Erkaymaz, Okan; Ozer, Mahmut

    2016-01-01

    Artificial intelligent systems have been widely used for diagnosis of diseases. Due to their importance, new approaches are attempted consistently to increase the performance of these systems. In this study, we introduce a new approach for diagnosis of diabetes based on the Small-World Feed Forward Artificial Neural Network (SW- FFANN). We construct the small-world network by following the Watts–Strogatz approach, and use this architecture for classifying the diabetes, and compare its performance with that of the regular or the conventional FFANN. We show that the classification performance of the SW-FFANN is better than that of the conventional FFANN. The SW-FFANN approach also results in both the highest output correlation and the best output error parameters. We also perform the accuracy analysis and show that SW-FFANN approach exhibits the highest classifier performance.

  4. Boolean Models of Biological Processes Explain Cascade-Like Behavior.

    Science.gov (United States)

    Chen, Hao; Wang, Guanyu; Simha, Rahul; Du, Chenghang; Zeng, Chen

    2016-01-29

    Biological networks play a key role in determining biological function and therefore, an understanding of their structure and dynamics is of central interest in systems biology. In Boolean models of such networks, the status of each molecule is either "on" or "off" and along with the molecules interact with each other, their individual status changes from "on" to "off" or vice-versa and the system of molecules in the network collectively go through a sequence of changes in state. This sequence of changes is termed a biological process. In this paper, we examine the common perception that events in biomolecular networks occur sequentially, in a cascade-like manner, and ask whether this is likely to be an inherent property. In further investigations of the budding and fission yeast cell-cycle, we identify two generic dynamical rules. A Boolean system that complies with these rules will automatically have a certain robustness. By considering the biological requirements in robustness and designability, we show that those Boolean dynamical systems, compared to an arbitrary dynamical system, statistically present the characteristics of cascadeness and sequentiality, as observed in the budding and fission yeast cell- cycle. These results suggest that cascade-like behavior might be an intrinsic property of biological processes.

  5. Ion-irradiation studies of cascade damage in metals

    International Nuclear Information System (INIS)

    Averback, R.S.

    1982-03-01

    Ion-irradiation studies of the fundamental aspects of cascade damage in metals are reviewed. The emphasis of these studies has been the determination of the primary state of damage (i.e. the arrangement of atoms in the cascade region prior to thermal migration of defects). Progress has been made towards understanding the damage function (i.e. the number of Frenkel pairs produced as a function of primary recoil atom energy), the spatial configuration of vacancies and interstitials in the cascade and the cascade-induced mixing of atoms. It is concluded for these studies that the agitation of the lattice in the vicinity of energetic displacement cascades stimulates the defect motion and that such thermal spike motion induces recombination and clustering of Frenkel defects. 9 figures

  6. Empirical confirmation of creative destruction from world trade data.

    Directory of Open Access Journals (Sweden)

    Peter Klimek

    Full Text Available We show that world trade network datasets contain empirical evidence that the dynamics of innovation in the world economy indeed follows the concept of creative destruction, as proposed by J.A. Schumpeter more than half a century ago. National economies can be viewed as complex, evolving systems, driven by a stream of appearance and disappearance of goods and services. Products appear in bursts of creative cascades. We find that products systematically tend to co-appear, and that product appearances lead to massive disappearance events of existing products in the following years. The opposite-disappearances followed by periods of appearances-is not observed. This is an empirical validation of the dominance of cascading competitive replacement events on the scale of national economies, i.e., creative destruction. We find a tendency that more complex products drive out less complex ones, i.e., progress has a direction. Finally we show that the growth trajectory of a country's product output diversity can be understood by a recently proposed evolutionary model of Schumpeterian economic dynamics.

  7. Empirical confirmation of creative destruction from world trade data.

    Science.gov (United States)

    Klimek, Peter; Hausmann, Ricardo; Thurner, Stefan

    2012-01-01

    We show that world trade network datasets contain empirical evidence that the dynamics of innovation in the world economy indeed follows the concept of creative destruction, as proposed by J.A. Schumpeter more than half a century ago. National economies can be viewed as complex, evolving systems, driven by a stream of appearance and disappearance of goods and services. Products appear in bursts of creative cascades. We find that products systematically tend to co-appear, and that product appearances lead to massive disappearance events of existing products in the following years. The opposite-disappearances followed by periods of appearances-is not observed. This is an empirical validation of the dominance of cascading competitive replacement events on the scale of national economies, i.e., creative destruction. We find a tendency that more complex products drive out less complex ones, i.e., progress has a direction. Finally we show that the growth trajectory of a country's product output diversity can be understood by a recently proposed evolutionary model of Schumpeterian economic dynamics.

  8. Modeling and Analysis of Epidemic Diffusion within Small-World Network

    Directory of Open Access Journals (Sweden)

    Ming Liu

    2012-01-01

    Full Text Available To depict the rule of epidemic diffusion, two different models, the Susceptible-Exposure-Infected-Recovered-Susceptible (SEIRS model and the Susceptible-Exposure-Infected-Quarantine-Recovered-Susceptible (SEIQRS model, are proposed and analyzed within small-world network in this paper. Firstly, the epidemic diffusion models are constructed with mean-filed theory, and condition for the occurrence of disease diffusion is explored. Then, the existence and global stability of the disease-free equilibrium and the endemic equilibrium for these two complex epidemic systems are proved by differential equations knowledge and Routh-Hurwiz theory. At last, a numerical example which includes key parameters analysis and critical topic discussion is presented to test how well the proposed two models may be applied in practice. These works may provide some guidelines for decision makers when coping with epidemic diffusion controlling problems.

  9. New approach to small scale power could light up much of the developing world

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, J.

    2011-01-15

    The modern conveniences requiring electricity have been out of reach for almost half of the world's population because they live too far from the grid. Innovative technology combined with creative new business models could significantly improve the quality of life for millions of people. This article discussed a small scale renewable energy system that could ensure that villages all over the world have access to radios, lights, refrigeration and other critical technologies. The article also noted the potential implications in terms of health, education and the general standard of living for millions of people. The basic model involves setting up small solar panels in a good location in a village or on a farm. The panels can be used to charge up equipment that is either on-site or portable. This article described how to achieve economies of scale through mass production of many similar units. The project has been tested in Brazil and a donation to the project of $100,000 will be used to install a solar-powered public infrastructure comprised of water pumping, school and an Internet station. The funds will also be used to provide 70 solar lanterns for children living in two villages on the Rio Tapajos, a tributary to the Amazon near Santarem. 1 fig.

  10. Cascading failure in the wireless sensor scale-free networks

    Science.gov (United States)

    Liu, Hao-Ran; Dong, Ming-Ru; Yin, Rong-Rong; Han, Li

    2015-05-01

    In the practical wireless sensor networks (WSNs), the cascading failure caused by a failure node has serious impact on the network performance. In this paper, we deeply research the cascading failure of scale-free topology in WSNs. Firstly, a cascading failure model for scale-free topology in WSNs is studied. Through analyzing the influence of the node load on cascading failure, the critical load triggering large-scale cascading failure is obtained. Then based on the critical load, a control method for cascading failure is presented. In addition, the simulation experiments are performed to validate the effectiveness of the control method. The results show that the control method can effectively prevent cascading failure. Project supported by the Natural Science Foundation of Hebei Province, China (Grant No. F2014203239), the Autonomous Research Fund of Young Teacher in Yanshan University (Grant No. 14LGB017) and Yanshan University Doctoral Foundation, China (Grant No. B867).

  11. Energy and carbon balances of wood cascade chains

    Energy Technology Data Exchange (ETDEWEB)

    Sathre, Roger; Gustavsson, Leif [Ecotechnology, Mid Sweden University, SE-831 25 OEstersund (Sweden)

    2006-07-15

    In this study we analyze the energy and carbon balances of various cascade chains for recovered wood lumber. Post-recovery options include reuse as lumber, reprocessing as particleboard, pulping to form paper products, and burning for energy recovery. We compare energy and carbon balances of chains of cascaded products to the balances of products obtained from virgin wood fiber or from non-wood material. We describe and quantify several mechanisms through which cascading can affect the energy and carbon balances: direct cascade effects due to different properties and logistics of virgin and recovered materials, substitution effects due to the reduced demand for non-wood materials when wood is cascaded, and land use effects due to alternative possible land uses when less timber harvest is needed because of wood cascading. In some analyses we assume the forest is a limiting resource, and in others we include a fixed amount of forest land from which biomass can be harvested for use as material or biofuel. Energy and carbon balances take into account manufacturing processes, recovery and transportation energy, material recovery losses, and forest processes. We find that land use effects have the greatest impact on energy and carbon balances, followed by substitution effects, while direct cascade effects are relatively minor. (author)

  12. Multiple Linear Regression for Reconstruction of Gene Regulatory Networks in Solving Cascade Error Problems

    Directory of Open Access Journals (Sweden)

    Faridah Hani Mohamed Salleh

    2017-01-01

    Full Text Available Gene regulatory network (GRN reconstruction is the process of identifying regulatory gene interactions from experimental data through computational analysis. One of the main reasons for the reduced performance of previous GRN methods had been inaccurate prediction of cascade motifs. Cascade error is defined as the wrong prediction of cascade motifs, where an indirect interaction is misinterpreted as a direct interaction. Despite the active research on various GRN prediction methods, the discussion on specific methods to solve problems related to cascade errors is still lacking. In fact, the experiments conducted by the past studies were not specifically geared towards proving the ability of GRN prediction methods in avoiding the occurrences of cascade errors. Hence, this research aims to propose Multiple Linear Regression (MLR to infer GRN from gene expression data and to avoid wrongly inferring of an indirect interaction (A → B → C as a direct interaction (A → C. Since the number of observations of the real experiment datasets was far less than the number of predictors, some predictors were eliminated by extracting the random subnetworks from global interaction networks via an established extraction method. In addition, the experiment was extended to assess the effectiveness of MLR in dealing with cascade error by using a novel experimental procedure that had been proposed in this work. The experiment revealed that the number of cascade errors had been very minimal. Apart from that, the Belsley collinearity test proved that multicollinearity did affect the datasets used in this experiment greatly. All the tested subnetworks obtained satisfactory results, with AUROC values above 0.5.

  13. Serviceability Assessment for Cascading Failures in Water Distribution Network under Seismic Scenario

    Directory of Open Access Journals (Sweden)

    Qing Shuang

    2016-01-01

    Full Text Available The stability of water service is a hot point in industrial production, public safety, and academic research. The paper establishes a service evaluation model for the water distribution network (WDN. The serviceability is measured in three aspects: (1 the functionality of structural components under disaster environment; (2 the recognition of cascading failure process; and (3 the calculation of system reliability. The node and edge failures in WDN are interrelated under seismic excitations. The cascading failure process is provided with the balance of water supply and demand. The matrix-based system reliability (MSR method is used to represent the system events and calculate the nonfailure probability. An example is used to illustrate the proposed method. The cascading failure processes with different node failures are simulated. The serviceability is analyzed. The critical node can be identified. The result shows that the aged network has a greater influence on the system service under seismic scenario. The maintenance could improve the antidisaster ability of WDN. Priority should be given to controlling the time between the initial failure and the first secondary failure, for taking postdisaster emergency measures within this time period can largely cut down the spread of cascade effect in the whole WDN.

  14. Cascaded impedance networks for NPC inverter

    DEFF Research Database (Denmark)

    Li, Ding; Gao, Feng; Loh, Poh Chiang

    2010-01-01

    they are subject to the renewable sources. To date, three distinct types of impedance networks can be summarized for implementing a hybrid source impedance network, which can in principle be combined and cascaded before connected to a NPC inverter by proposed two ways. The resulting cascaded impedance network NPC...

  15. A Multifractal Detrended Fluctuation Analysis of the Ising Financial Markets Model with Small World Topology

    International Nuclear Information System (INIS)

    Zhang Ang-Hui; Li Xiao-Wen; Su Gui-Feng; Zhang Yi

    2015-01-01

    We present a multifractal detrended fluctuation analysis (MFDFA) of the time series of return generated by our recently-proposed Ising financial market model with underlying small world topology. The result of the MFDFA shows that there exists obvious multifractal scaling behavior in produced time series. We compare the MFDFA results for original time series with those for shuffled series, and find that its multifractal nature is due to two factors: broadness of probability density function of the series and different correlations in small- and large-scale fluctuations. This may provide new insight to the problem of the origin of multifractality in financial time series. (paper)

  16. Medication adherence, cascade screening, and lifestyle patterns among women with hypercholesterolemia: Results from the WomenHeart survey.

    Science.gov (United States)

    Benson, Gretchen; Witt, Dawn R; VanWormer, Jeffrey J; Campbell, Susan M; Sillah, Arthur; Hayes, Sharonne N; Lui, Matt; Gulati, Martha

    2016-01-01

    Hypercholesterolemia is a major risk factor for cardiovascular disease. Women with hypercholesterolemia and familial hypercholesterolemia (FH) are a high-risk group often underdiagnosed, undertreated, and unaware of the need for cascade screening. The objectives were to identify the prevalence of hypercholesterolemia and FH in 2 national databases, explore lifestyle/medication adherence, and examine rates of cascade screening (lipid testing in all first-degree relatives) among those with FH. This was a cross-sectional study of women who completed an online survey in 2014. Outcomes were examined for 3 groups: diagnosed, probable, and no FH. For FH, multivariable logistic regression was used to examine the association between family member screening for FH and sociodemographic and/or clinical characteristics. There were 761 respondents with a mean (±standard deviation) age of 59 ± 10.1 years; 26% reported FH, 22% probable FH, and 51% no FH. Eighty-three percent of the total sample and 95% with FH take a statin. In those with hypercholesterolemia and FH, 65% and 58% reported high medication adherence, respectively. Women with probable FH consumed significantly fewer fruits/vegetables and were less active. FH cascade screening was: siblings 54%, parents 37%, and children 34%. Marital status, annual household income, and diabetes were significantly associated with cascade screening. In a survey of informed women with hypercholesterolemia and FH, cascade screening is underused. Our findings warrant increased efforts to identify cascade screening barriers. Early detection and treatment of hypercholesterolemia/FH is a priority for women, and their first-degree relatives, as this may dramatically reduce cardiovascular disease impact. Copyright © 2016 National Lipid Association. Published by Elsevier Inc. All rights reserved.

  17. Reduced small world brain connectivity in probands with a family history of epilepsy.

    Science.gov (United States)

    Bharath, R D; Chaitanya, G; Panda, R; Raghavendra, K; Sinha, S; Sahoo, A; Gohel, S; Biswal, B B; Satishchandra, P

    2016-12-01

    The role of inheritance in ascertaining susceptibility to epilepsy is well established, although the pathogenetic mechanisms are still not very clear. Interviewing for a positive family history is a popular epidemiological tool in the understanding of this susceptibility. Our aim was to visualize and localize network abnormalities that could be associated with a positive family history in a group of patients with hot water epilepsy (HWE) using resting-state functional magnetic resonance imaging (rsfMRI). Graph theory analysis of rsfMRI (clustering coefficient γ; path length λ; small worldness σ) in probands with a positive family history of epilepsy (FHE+, 25) were compared with probands without FHE (FHE-, 33). Whether a closer biological relationship was associated with a higher likelihood of network abnormalities was also ascertained. A positive family history of epilepsy had decreased γ, increased λ and decreased σ in bilateral temporofrontal regions compared to FHE- (false discovery rate corrected P ≤ 0.0062). These changes were more pronounced in probands having first degree relatives and siblings with epilepsy. Probands with multiple types of epilepsy in the family showed decreased σ in comparison to only HWE in the family. Graph theory analysis of the rsfMRI can be used to understand the neurobiology of diseases like genetic susceptibility in HWE. Reduced small worldness, proportional to the degree of relationship, is consistent with the current understanding that disease severity is higher in closer biological relations. © 2016 EAN.

  18. Learning Cascading

    CERN Document Server

    Covert, Michael

    2015-01-01

    This book is intended for software developers, system architects and analysts, big data project managers, and data scientists who wish to deploy big data solutions using the Cascading framework. You must have a basic understanding of the big data paradigm and should be familiar with Java development techniques.

  19. Mathematical modeling of the static and dynamic behavior of the operational parameters of isotopic separation cascades composed of ultracentrifuges

    International Nuclear Information System (INIS)

    Portoghese, Celia Christiani Paschoa

    2002-01-01

    Several different mathematical models that make it possible to plan, design and follow the operation of uranium isotopic separation cascades using the gaseous ultracentrifugation process are presented, discussed and tested. Models to be used in the planning and conception phases use theoretical hypothesis, making it possible to calculate approximate values for the flow rate and isotopic composition of the cascade internal streams. Twelve theoretical models developed to perform this task are discussed and compared. The theoretical models that have greater applicability are identified. Models to be used for the complete dimensioning of a cascade, before its construction, called semi-empirical models, use experimental results obtained in ultracentrifuges individual testes combined with theoretical equations, allowing to calculate accurate values for the flow rate, pressure and isotopic composition of the cascade internal streams. Thirteen semi-empirical models developed to perform this task are presented, five of them are widely discussed and one of them is validated through comparison with experimental results. In order to follow the operation of a cascade, it is necessary to develop models to simulate its behavior in operational conditions other than the nominal, defined in the project. Three semi-empirical models to make this kind of simulation are presented and one of them is validated through comparison with experimental results. Finally, it is necessary to have tools that simulate the cascade behavior during transients. Two dynamic models developed to perform this task are presented and compared. The dynamic model capable to simulate results closer ti the real behaviour of a cascade during three different kinds of transient is identified, through comparison between simulated and experimental results. (author)

  20. Displacement cascades and defect annealing in tungsten, Part III: The sensitivity of cascade annealing in tungsten to the values of kinetic parameters

    Energy Technology Data Exchange (ETDEWEB)

    Nandipati, Giridhar, E-mail: giridhar.nandipati@pnnl.gov [Pacific Northwest National Laboratory, Richland, WA (United States); Setyawan, Wahyu; Heinisch, Howard L. [Pacific Northwest National Laboratory, Richland, WA (United States); Roche, Kenneth J. [Pacific Northwest National Laboratory, Richland, WA (United States); Department of Physics, University of Washington, Seattle, WA 98195 (United States); Kurtz, Richard J. [Pacific Northwest National Laboratory, Richland, WA (United States); Wirth, Brian D. [University of Tennessee, Knoxville, TN (United States)

    2015-07-15

    A study has been performed using object kinetic Monte Carlo (OKMC) simulations to investigate various aspects of cascade aging in bulk tungsten (W) and to determine its sensitivity to the kinetic parameters. The primary focus is on how the kinetic parameters affect the intracascade recombination of defects. Results indicate that, due to the disparate mobilities of SIA and vacancy clusters, annealing is dominated by SIA migration even at 2050 K. It was found that for 100 keV cascades initiated at 300 K, recombination is dominated by the annihilation of large defect clusters, while for all the other primary knock-on atom (PKA) energies and temperatures, recombination is primarily due to the migration and rotation of small SIA clusters, while the large SIA clusters escape the simulation cell. The annealing efficiency exhibits an inverse U-shaped curve behavior with increasing temperature, especially at large PKA energies, caused by the asymmetry in SIA and vacancy clustering assisted by the large differences in their mobilities. This behavior is unaffected by the dimensionality of SIA migration, and it persists over a broad range of relative mobilities of SIAs and vacancies.

  1. Time reversibility of quantum diffusion in small-world networks

    Science.gov (United States)

    Han, Sung-Guk; Kim, Beom Jun

    2012-02-01

    We study the time-reversal dynamics of a tight-binding electron in the Watts-Strogatz (WS) small-world networks. The localized initial wave packet at time t = 0 diffuses as time proceeds until the time-reversal operation, together with the momentum perturbation of the strength η, is made at the reversal time T. The time irreversibility is measured by I = |Π( t = 2 T) - Π( t = 0)|, where Π is the participation ratio gauging the extendedness of the wavefunction and for convenience, t is measured forward even after the time reversal. When η = 0, the time evolution after T makes the wavefunction at t = 2 T identical to the one at t = 0, and we find I = 0, implying a null irreversibility or a complete reversibility. On the other hand, as η is increased from zero, the reversibility becomes weaker, and we observe enhancement of the irreversibility. We find that I linearly increases with increasing η in the weakly-perturbed region, and that the irreversibility is much stronger in the WS network than in the local regular network.

  2. The small world yields the most effective information spreading

    International Nuclear Information System (INIS)

    Lü Linyuan; Chen Duanbing; Zhou Tao

    2011-01-01

    The spreading dynamics of information and diseases are usually analyzed by using a unified framework and analogous models. In this paper, we propose a model to emphasize the essential difference between information spreading and epidemic spreading, where the memory effects, the social reinforcement and the non-redundancy of contacts are taken into account. Under certain conditions, the information spreads faster and broader in regular networks than in random networks, which to some extent supports the recent experimental observation of spreading in online society (Centola D 2010 Science 329 1194). At the same time, the simulation result indicates that the random networks tend to be favorable for effective spreading when the network size increases. This challenges the validity of the above-mentioned experiment for large-scale systems. More importantly, we show that the spreading effectiveness can be sharply enhanced by introducing a little randomness into the regular structure, namely the small-world networks yield the most effective information spreading. This work provides insights into the role of local clustering in information spreading. (paper)

  3. Cascading failures with local load redistribution in interdependent Watts-Strogatz networks

    Science.gov (United States)

    Hong, Chen; Zhang, Jun; Du, Wen-Bo; Sallan, Jose Maria; Lordan, Oriol

    2016-05-01

    Cascading failures of loads in isolated networks have been studied extensively over the last decade. Since 2010, such research has extended to interdependent networks. In this paper, we study cascading failures with local load redistribution in interdependent Watts-Strogatz (WS) networks. The effects of rewiring probability and coupling strength on the resilience of interdependent WS networks have been extensively investigated. It has been found that, for small values of the tolerance parameter, interdependent networks are more vulnerable as rewiring probability increases. For larger values of the tolerance parameter, the robustness of interdependent networks firstly decreases and then increases as rewiring probability increases. Coupling strength has a different impact on robustness. For low values of coupling strength, the resilience of interdependent networks decreases with the increment of the coupling strength until it reaches a certain threshold value. For values of coupling strength above this threshold, the opposite effect is observed. Our results are helpful to understand and design resilient interdependent networks.

  4. Using graph theory to analyze the vulnerability of process plants in the context of cascading effects

    International Nuclear Information System (INIS)

    Khakzad, Nima; Reniers, Genserik

    2015-01-01

    Dealing with large quantities of flammable and explosive materials, usually at high-pressure high-temperature conditions, makes process plants very vulnerable to cascading effects compared with other infrastructures. The combination of the extremely low frequency of cascading effects and the high complexity and interdependencies of process plants makes risk assessment and vulnerability analysis of process plants very challenging in the context of such events. In the present study, cascading effects were represented as a directed graph; accordingly, the efficacy of a set of graph metrics and measurements was examined in both unit and plant-wide vulnerability analysis of process plants. We demonstrated that vertex-level closeness and betweenness can be used in the unit vulnerability analysis of process plants for the identification of critical units within a process plant. Furthermore, the graph-level closeness metric can be used in the plant-wide vulnerability analysis for the identification of the most vulnerable plant layout with respect to the escalation of cascading effects. Furthermore, the results from the application of the graph metrics have been verified using a Bayesian network methodology. - Highlights: • Graph metrics can effectively be employed to identify vulnerable units and layouts in process plants. • Units with larger vertex-level closeness result in more probable and severe cascading effects. • Units with larger vertex-level betweenness contribute more to the escalation of cascading effects. • Layouts with larger graph-level closeness are more vulnerable to the escalation of cascading effects

  5. Computation of inverse magnetic cascades

    International Nuclear Information System (INIS)

    Montgomery, D.

    1981-10-01

    Inverse cascades of magnetic quantities for turbulent incompressible magnetohydrodynamics are reviewed, for two and three dimensions. The theory is extended to the Strauss equations, a description intermediate between two and three dimensions appropriate to tokamak magnetofluids. Consideration of the absolute equilibrium Gibbs ensemble for the system leads to a prediction of an inverse cascade of magnetic helicity, which may manifest itself as a major disruption. An agenda for computational investigation of this conjecture is proposed

  6. Chaos in complex motor networks induced by Newman—Watts small-world connections

    International Nuclear Information System (INIS)

    Wei Du-Qu; Luo Xiao-Shu; Zhang Bo

    2011-01-01

    We investigate how dynamical behaviours of complex motor networks depend on the Newman—Watts small-world (NWSW) connections. Network elements are described by the permanent magnet synchronous motor (PMSM) with the values of parameters at which each individual PMSM is stable. It is found that with the increase of connection probability p, the motor in networks becomes periodic and falls into chaotic motion as p further increases. These phenomena imply that NWSW connections can induce and enhance chaos in motor networks. The possible mechanism behind the action of NWSW connections is addressed based on stability theory. (interdisciplinary physics and related areas of science and technology)

  7. The structure and dynamics of energetic displacement cascades in Cu and Ni. A molecular dynamics computer simulation study

    International Nuclear Information System (INIS)

    Diaz de la Rubia, T.

    1989-01-01

    The primary state of damage present in a solid as a result of particle irradiation has been a topic of interest to the physics and materials research community over the last forty years. Energetic displacement cascades resulting from the heavy ion irradiation of a solid play a prominent role in radiation damage and non-equilibrium processing of materials; however, their study has been hampered by the small size (∼10 -20 cm 3 ) and short lifetime (∼10 -11 s) as well as by their highly non-homogeneous nature. In this work, the molecular dynamics computer simulation technique is employed to study the structure and dynamics of energetic displacement cascades in Cu and Ni. The atomic interactions in Cu were described with the use of the Gibson II form of the Born-Mayer pair potential while for Ni the Johnson-Erginsoy pair potential was employed. Calculations were also carried out with the use of the embedded atom method many-body potentials. The results provide the first detailed microscopic description of the evolution of the cascade. The author shows for the first time, that a process akin to melting takes place in the core of the cascade. Atomic mixing, point defect production and point defect agglomeration, all processes directly related to the evolution of the cascade, are then explained in terms of a simple model in which the liquid-like nature of the cascade plays a dominant role in determining the primary state of damage

  8. Non-spill control squared cascade

    International Nuclear Information System (INIS)

    Kai, Tsunetoshi; Inoue, Yoshiya; Oya, Akio; Suemori, Nobuo.

    1974-01-01

    Object: To reduce a mixed loss thus enhancing separating efficiency by the provision of a simple arrangement wherein a reflux portion in a conventional spill control squared cascade is replaced by a special stage including centrifugal separators. Structure: Steps in the form of a square cascade, in which a plurality of centrifugal separators are connected by pipe lines, are accumulated in multistage fashion to form a squared cascade. Between the adjoining steps is disposed a special stage including a centrifugal separator which receives both lean flow from the upper step and rich flow from the lower step. The centrifugal separator in the special stage has its rich side connected to the upper step and its lean side connected to the lower step. Special stages are each disposed at the upper side of the uppermost step and at the lower side of the lowermost step. (Kamimura, M.)

  9. Dynamics robustness of cascading systems.

    Directory of Open Access Journals (Sweden)

    Jonathan T Young

    2017-03-01

    Full Text Available A most important property of biochemical systems is robustness. Static robustness, e.g., homeostasis, is the insensitivity of a state against perturbations, whereas dynamics robustness, e.g., homeorhesis, is the insensitivity of a dynamic process. In contrast to the extensively studied static robustness, dynamics robustness, i.e., how a system creates an invariant temporal profile against perturbations, is little explored despite transient dynamics being crucial for cellular fates and are reported to be robust experimentally. For example, the duration of a stimulus elicits different phenotypic responses, and signaling networks process and encode temporal information. Hence, robustness in time courses will be necessary for functional biochemical networks. Based on dynamical systems theory, we uncovered a general mechanism to achieve dynamics robustness. Using a three-stage linear signaling cascade as an example, we found that the temporal profiles and response duration post-stimulus is robust to perturbations against certain parameters. Then analyzing the linearized model, we elucidated the criteria of when signaling cascades will display dynamics robustness. We found that changes in the upstream modules are masked in the cascade, and that the response duration is mainly controlled by the rate-limiting module and organization of the cascade's kinetics. Specifically, we found two necessary conditions for dynamics robustness in signaling cascades: 1 Constraint on the rate-limiting process: The phosphatase activity in the perturbed module is not the slowest. 2 Constraints on the initial conditions: The kinase activity needs to be fast enough such that each module is saturated even with fast phosphatase activity and upstream changes are attenuated. We discussed the relevance of such robustness to several biological examples and the validity of the above conditions therein. Given the applicability of dynamics robustness to a variety of systems, it

  10. Molecular dynamics simulation of displacement cascades in iron-alpha; Cascades de deplacements atomiques dans le FER-alpha simulation par dynamique moleculaire

    Energy Technology Data Exchange (ETDEWEB)

    Vascon, R

    1997-12-31

    Radiation damage by neutrons or ions in bcc iron has been investigated by molecular dynamics simulations using an embedded atom type many-body potential (EAM). Displacement cascades with energies of 1 to 30 keV were generated in the microcanonical system where the number of atoms (up to 1.5 million) is chosen high enough to compensate the fact that the dissipation of energy is not taken into account in our model. The defect number at the end of cascade lifetime was found to be 60 percent of the NRT standard value. This tendency is in good agreement with experimental data. However, compared with other simulations in iron, we found significant differences in the defect production and distribution. The comparison with results obtained form simulations of cascades in other metals, leads on the one hand to a higher value of the defect number in bcc iron than in fcc metals like copper or nickel, and on the other hand to a ratio, between the number of replacements and the number of defects, lower in iron ( 100). We observed the transient melting of the core of the cascade during simulations. We showed that a higher value of the initial iron crystal temperature, as the mass difference between the components of an artificial binary alloy Fe-X(X=Al,Sb,Au,U) both produce a `cascade effect`: a decrease of the number of defects and an increase of the number of replacements. We also showed up the quasi-channeling of some atoms in high energy cascades. They are at the origin of sub-cascades formation; as a result they induce an opposite effect to the `cascade effect`. (author). 286 refs.

  11. A cryogenic distillation column cascade for a fusion reactor

    International Nuclear Information System (INIS)

    Kinoshita, M.

    1984-01-01

    A cryogenic distillation column cascade composed of only two columns is proposed. Compared with the Tritium Systems Test Assembly (TSTA) cascade, the tritium inventory is about 1.5 times more and the packed height of the highest column increases by about 40%. However, the number of the columns is halved with the separation performance unchanged. The number of the instruments needed and the number of the process parameters to be monitored are also reduced. Unlike in the case of the TSTA cascade, the performance of the proposed cascade is not subject to the flow rate of the neutral beam injector recycle stream. The high performance can be maintained even if the protium percentage in the raw fuel input increases significantly (e.g., from 1 to 3%), just by adjusting the flow rates of the top, bottom, and side streams. Because of this great flexibility, it is worthwhile to build and study the proposed cascade as a possible alternative to the TSTA cascade

  12. Market-oriented Programming Using Small-world Networks for Controlling Building Environments

    Science.gov (United States)

    Shigei, Noritaka; Miyajima, Hiromi; Osako, Tsukasa

    The market model, which is one of the economic activity models, is modeled as an agent system, and applying the model to the resource allocation problem has been studied. For air conditioning control of building, which is one of the resource allocation problems, an effective method based on the agent system using auction has been proposed for traditional PID controller. On the other hand, it has been considered that this method is performed by decentralized control. However, its decentralization is not perfect, and its performace is not enough. In this paper, firstly, we propose a perfectly decentralized agent model and show its performance. Secondly, in order to improve the model, we propose the agent model based on small-world model. The effectiveness of the proposed model is shown by simulation.

  13. Building Keypoint Mappings on Multispectral Images by a Cascade of Classifiers with a Resurrection Mechanism

    Directory of Open Access Journals (Sweden)

    Yong Li

    2015-05-01

    Full Text Available Inspired by the boosting technique for detecting objects, this paper proposes a cascade structure with a resurrection mechanism to establish keypoint mappings on multispectral images. The cascade structure is composed of four steps by utilizing best bin first (BBF, color and intensity distribution of segment (CIDS, global information and the RANSAC process to remove outlier keypoint matchings. Initial keypoint mappings are built with the descriptors associated with keypoints; then, at each step, only a small number of keypoint mappings of a high confidence are classified to be incorrect. The unclassified keypoint mappings will be passed on to subsequent steps for determining whether they are correct. Due to the drawback of a classification rule, some correct keypoint mappings may be misclassified as incorrect at a step. Observing this, we design a resurrection mechanism, so that they will be reconsidered and evaluated by the rules utilized in subsequent steps. Experimental results show that the proposed cascade structure combined with the resurrection mechanism can effectively build more reliable keypoint mappings on multispectral images than existing methods.

  14. MOLECULAR DYNAMICS SIMULATIONS OF DISPLACEMENT CASCADES IN MOLYBDENUM

    International Nuclear Information System (INIS)

    Smith, Richard Whiting

    2003-01-01

    Molecular dynamics calculations have been employed to simulate displacement cascades in neutron irradiated Mo. A total of 90 simulations were conducted for PKA energies between 1 and 40 keV and temperatures from 298 to 923K. The results suggest very little effect of temperature on final defect count and configuration, but do display a temperature effect on peak defect generation prior to cascade collapse. Cascade efficiency, relative to the NRT model, is computed to lie between 1/4 and 1/3 in agreement with simulations performed on previous systems. There is a tendency for both interstitials and vacancies to cluster together following cascade collapse producing vacancy rich regions surrounded by interstitials. Although coming to rest in close proximity, the point defects comprising the clusters generally do not lie within the nearest neighbor positions of one another, except for the formation of dumbbell di-interstitials. Cascades produced at higher PKA energies (20 or 40 keV) exhibit the formation of subcascades

  15. Molecular Dynamics Simulations of displacement cascades in metallic systems

    International Nuclear Information System (INIS)

    Doan, N.V.; Tietze, H.

    1995-01-01

    We use Molecular Dynamics Computer Simulations to investigate defect production induced by energetic displacement cascades up to 10 keV in pure metals (Cu, Ni) and in ordered intermetallic alloys NiAl, Ni 3 Al. Various model potentials were employed to describe the many-body nature of the interactions: the RGL (Rosato-Guillope-Legrand) model was used in pure Cu and Ni simulations; the modified version of the Vitek, Ackland and Cserti potentials (due to Gao, Bacon and Ackland) in Ni 3 Al and the EAM potentials of Foiles and Daw modified by Rubini and Ballone in NiAl, Ni 3 Al were used in alloy simulations. Atomic mixing and disordering were studied into details owing to imaging techniques and determined at different phases of the cascades. Some mixing mechanisms were identified. Our results were compared with existing data and those obtained by similar Molecular Dynamics Simulations available in the literature. (orig.)

  16. Stochastic background of atmospheric cascades

    International Nuclear Information System (INIS)

    Wilk, G.; Wlodarczyk, Z.

    1993-01-01

    Fluctuations in the atmospheric cascades developing during the propagation of very high energy cosmic rays through the atmosphere are investigated using stochastic branching model of pure birth process with immigration. In particular, we show that the multiplicity distributions of secondaries emerging from gamma families are much narrower than those resulting from hadronic families. We argue that the strong intermittent like behaviour found recently in atmospheric families results from the fluctuations in the cascades themselves and are insensitive to the details of elementary interactions

  17. Geothermal segmentation of the Cascade Range in the USA

    Science.gov (United States)

    Guffanti, Marianne; Muffler, L.J.; Mariner, R.H.; Sherrod, D.R.; Smith, James G.; Blackwell, D.D.; Weaver, C.S.

    1990-01-01

    Characteristics of the crustal thermal regime of the Quaternary Cascades vary systematically along the range. Spatially congruent changes in volcanic vent distribution, volcanic extrusion rate, hydrothermal discharge rate, and regional conductive heat flow define 5 geothermal segments. These segments are, from north to south: (1) the Washington Cascades north of Mount Rainier, (2) the Cascades from Mount Rainier to Mount Hood, (3) the Oregon Cascades from south of Mount Hood to the California border, (4) northernmost California, including Mount Shasta and Medicine Lake volcano, and (5) the Lassen region of northern California. This segmentation indicates that geothermal resource potential is not uniform in the Cascade Range. Potential varies from high in parts of Oregon to low in Washington north of Mount Rainier.

  18. Eruptive history of South Sister, Oregon Cascades

    Science.gov (United States)

    Fierstein, J.; Hildreth, W.; Calvert, A.T.

    2011-01-01

    South Sister is southernmost and highest of the Three Sisters, three geologically dissimilar stratovolcanoes that together form a spectacular 20km reach along the Cascade crest in Oregon. North Sister is a monotonously mafic edifice as old as middle Pleistocene, Middle Sister a basalt-andesite-dacite cone built between 48 and 14ka, and South Sister is a basalt-free edifice that alternated rhyolitic and intermediate modes from 50ka to 2ka (largely contemporaneous with Middle Sister). Detailed mapping, 330 chemical analyses, and 42 radioisotopic ages show that the oldest exposed South Sister lavas were initially rhyolitic ~50ka. By ~37ka, rhyolitic lava flows and domes (72-74% SiO2) began alternating with radially emplaced dacite (63-68% SiO2) and andesite (59-63% SiO2) lava flows. Construction of a broad cone of silicic andesite-dacite (61-64% SiO2) culminated ~30ka in a dominantly explosive sequence that began with crater-forming andesitic eruptions that left fragmental deposits at least 200m thick. This was followed at ~27ka by growth of a steeply dipping summit cone of agglutinate-dominated andesite (56-60.5% SiO2) and formation of a summit crater ~800m wide. This crater was soon filled and overtopped by a thick dacite lava flow and then by >150m of dacitic pyroclastic ejecta. Small-volume dacite lavas (63-67% SiO2) locally cap the pyroclastic pile. A final sheet of mafic agglutinate (54-56% SiO2) - the most mafic product of South Sister - erupted from and drapes the small (300-m-wide) present-day summit crater, ending a summit-building sequence that lasted until ~22ka. A 20kyr-long-hiatus was broken by rhyolite eruptions that produced (1) the Rock Mesa coulee, tephra, and satellite domelets (73.5% SiO2) and (2) the Devils Chain of ~20 domes and short coulees (72.3-72.8% SiO2) from N-S vent alignments on South Sister's flanks. The compositional reversal from mafic summit agglutinate to recent rhyolites epitomizes the frequently changing compositional modes of the

  19. A developmental cascade perspective of paediatric obesity: a conceptual model and scoping review.

    Science.gov (United States)

    Smith, Justin D; Egan, Kaitlyn N; Montaño, Zorash; Dawson-McClure, Spring; Jake-Schoffman, Danielle E; Larson, Madeline; St George, Sara M

    2018-04-05

    Considering the immense challenge of preventing obesity, the time has come to reconceptualise the way we study the obesity development in childhood. The developmental cascade model offers a longitudinal framework to elucidate the way cumulative consequences and spreading effects of risk and protective factors, across and within biopsychosocial spheres and phases of development, can propel individuals towards obesity. In this article, we use a theory-driven model-building approach and a scoping review that included 310 published studies to propose a developmental cascade model of paediatric obesity. The proposed model provides a basis for testing hypothesised cascades with multiple intervening variables and complex longitudinal processes. Moreover, the model informs future research by resolving seemingly contradictory findings on pathways to obesity previously thought to be distinct (low self-esteem, consuming sugary foods, and poor sleep cause obesity) that are actually processes working together over time (low self-esteem causes consumption of sugary foods which disrupts sleep quality and contributes to obesity). The findings of such inquiries can aid in identifying the timing and specific targets of preventive interventions across and within developmental phases. The implications of such a cascade model of paediatric obesity for health psychology and developmental and prevention sciences are discussed.

  20. Phase synchronization of non-Abelian oscillators on small-world networks

    Energy Technology Data Exchange (ETDEWEB)

    Gu, Zhi-Ming [College of Science, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Zhao, Ming [Department of Modern Physics, University of Science and Technology of China, Hefei 230026 (China); Zhou, Tao [Department of Modern Physics, University of Science and Technology of China, Hefei 230026 (China)]. E-mail: zhutou@ustc.edu; Zhu, Chen-Ping [College of Science, Nanjing University of Aeronautics and Astronautics, Nanjing 210016 (China); Wang, Bing-Hong [Department of Modern Physics, University of Science and Technology of China, Hefei 230026 (China)

    2007-02-26

    In this Letter, by extending the concept of Kuramoto oscillator to the left-invariant flow on general Lie group, we investigate the generalized phase synchronization on networks. The analyses and simulations of some typical dynamical systems on Watts-Strogatz networks are given, including the n-dimensional torus, the identity component of 3-dimensional general linear group, the special unitary group, and the special orthogonal group. In all cases, the greater disorder of networks will predict better synchronizability, and the small-world effect ensures the global synchronization for sufficiently large coupling strength. The collective synchronized behaviors of many dynamical systems, such as the integrable systems, the two-state quantum systems and the top systems, can be described by the present phase synchronization frame. In addition, it is intuitive that the low-dimensional systems are more easily to synchronize, however, to our surprise, we found that the high-dimensional systems display obviously synchronized behaviors in regular networks, while these phenomena cannot be observed in low-dimensional systems.

  1. Phase synchronization of non-Abelian oscillators on small-world networks

    International Nuclear Information System (INIS)

    Gu, Zhi-Ming; Zhao, Ming; Zhou, Tao; Zhu, Chen-Ping; Wang, Bing-Hong

    2007-01-01

    In this Letter, by extending the concept of Kuramoto oscillator to the left-invariant flow on general Lie group, we investigate the generalized phase synchronization on networks. The analyses and simulations of some typical dynamical systems on Watts-Strogatz networks are given, including the n-dimensional torus, the identity component of 3-dimensional general linear group, the special unitary group, and the special orthogonal group. In all cases, the greater disorder of networks will predict better synchronizability, and the small-world effect ensures the global synchronization for sufficiently large coupling strength. The collective synchronized behaviors of many dynamical systems, such as the integrable systems, the two-state quantum systems and the top systems, can be described by the present phase synchronization frame. In addition, it is intuitive that the low-dimensional systems are more easily to synchronize, however, to our surprise, we found that the high-dimensional systems display obviously synchronized behaviors in regular networks, while these phenomena cannot be observed in low-dimensional systems

  2. Cascade processes in kaonic and muonic atoms

    International Nuclear Information System (INIS)

    Faifman, M.P.; Men'shikov, L.I.

    2003-01-01

    Cascade processes in exotic (kaonic and muonic) hydrogen/deuterium have been studied with the quantum-classical Monte Carlo code (QCMC) developed for 'ab initio' - calculations. It has been shown that the majority of kaonic hydrogen atoms during cascade are accelerated to high energies E ∼ 100 eV, which leads to a much lower value for the calculated yields Y of x-rays than predicted by the 'standard cascade model'. The modified QCMC scheme has been applied to the study of the cascade in μp and μd muonic atoms. A comparison of the calculated yields for K-series x-rays with experimental data directly indicates that the molecular structure of the hydrogen target and new types of non-radiative transitions are essential for the light muonic atoms, while they are negligible for heavy (kaonic) atoms. These processes have been considered and estimates of their probabilities are presented. (author)

  3. Rescuing Ecosystems from Extinction Cascades

    Science.gov (United States)

    Sahasrabudhe, Sagar; Motter, Adilson

    2010-03-01

    Food web perturbations stemming from climate change, overexploitation, invasive species, and natural disasters often cause an initial loss of species that results in a cascade of secondary extinctions. Using a predictive modeling framework, here we will present a systematic network-based approach to reduce the number of secondary extinctions. We will show that the extinction of one species can often be compensated by the concurrent removal of a second specific species, which is a counter-intuitive effect not previously tested in complex food webs. These compensatory perturbations frequently involve long-range interactions that are not a priori evident from local predator-prey relationships. Strikingly, in numerous cases even the early removal of a species that would eventually be extinct by the cascade is found to significantly reduce the number of cascading extinctions. Other nondestructive interventions based on partial removals and growth suppression and/or mortality increase are shown to sometimes prevent all secondary extinctions.

  4. Basic characteristics of a low uranium enrichment cascade by centrifugation, (2)

    International Nuclear Information System (INIS)

    Kai, Tsunetoshi

    1975-01-01

    The theory for a cascade of centrifuges described in the preceding report of the same general title is further developed. First, equations describing the distributions of the flow and the mole concentration are derived from the material balance relations for a square cascade. Corresponding equations are next obtained to cover a squared-off cascade consisting of a series of square cascades. A computer program is outlined which makes it possible to obtain the shape of the most efficient squared-off cascade. The efficiency of the current form of squared-off centrifuge cascade with reflux pipes is found to be lower than obtainable with gaseous diffusion. The efficiency can be improved by the adoption of a tapered squared-off cascade with centrifuges provided with eccentric cuts to take the place of reflux pipes. The dynamic characteristics are also discussed. Analysis of the start-up behavior reveals that the equilibrium time of the centrifuge cascade is much shorter than for a coresponding gaseous diffusion cascade, and that the mole concentration of the product rapidly rises to attain steady state condition. It is also found that even when the feed flow rate fluctuates, the mole concentration of the product is relatively stable. The effect of a centrifuge failure in the cascade is examined. The optimum mole concentration for the waste effluent discarded from the cascade is calculated from the viewpoint of cost. (auth.)

  5. Molecular dynamics studies of displacement cascades

    International Nuclear Information System (INIS)

    Averback, R.S.; Hsieh, Horngming; Diaz de la Rubia, T.

    1990-02-01

    Molecular-dynamics simulations of cascades in Cu and Ni with primary-knock-on energies up to 5 keV and lattice temperatures in the range 0 K--700 K are described. Interatomic forces were represented by either the Gibson II (Cu) or Johnson-Erginsoy (Ni) potentials in most of this work, although some simulations using ''Embedded Atom Method'' potentials, e.g., for threshold events in Ni 3 Al, are also presented. The results indicate that the primary state of damage produced by displacement cascades is controlled by two phenomena, replacement collision sequences during the collisional phase of the cascade and local melting during the thermal spike. As expected, the collisional phase is rather similar in Cu and Ni, however, the thermal spike is of longer duration and has a more pronounced influence in Cu than Ni. When the ambient temperature of the lattice is increased, the melt zones are observed to both increase in size and cool more slowly. This has the effect of reducing defect production and enhancing atomic mixing and disordering. The implications of these results for defect production, cascade collapse, atomic disordering will be discussed. 34 refs., 7 figs., 2 tabs

  6. Forecasting Social Unrest Using Activity Cascades.

    Science.gov (United States)

    Cadena, Jose; Korkmaz, Gizem; Kuhlman, Chris J; Marathe, Achla; Ramakrishnan, Naren; Vullikanti, Anil

    2015-01-01

    Social unrest is endemic in many societies, and recent news has drawn attention to happenings in Latin America, the Middle East, and Eastern Europe. Civilian populations mobilize, sometimes spontaneously and sometimes in an organized manner, to raise awareness of key issues or to demand changes in governing or other organizational structures. It is of key interest to social scientists and policy makers to forecast civil unrest using indicators observed on media such as Twitter, news, and blogs. We present an event forecasting model using a notion of activity cascades in Twitter (proposed by Gonzalez-Bailon et al., 2011) to predict the occurrence of protests in three countries of Latin America: Brazil, Mexico, and Venezuela. The basic assumption is that the emergence of a suitably detected activity cascade is a precursor or a surrogate to a real protest event that will happen "on the ground." Our model supports the theoretical characterization of large cascades using spectral properties and uses properties of detected cascades to forecast events. Experimental results on many datasets, including the recent June 2013 protests in Brazil, demonstrate the effectiveness of our approach.

  7. Forecasting Social Unrest Using Activity Cascades.

    Directory of Open Access Journals (Sweden)

    Jose Cadena

    Full Text Available Social unrest is endemic in many societies, and recent news has drawn attention to happenings in Latin America, the Middle East, and Eastern Europe. Civilian populations mobilize, sometimes spontaneously and sometimes in an organized manner, to raise awareness of key issues or to demand changes in governing or other organizational structures. It is of key interest to social scientists and policy makers to forecast civil unrest using indicators observed on media such as Twitter, news, and blogs. We present an event forecasting model using a notion of activity cascades in Twitter (proposed by Gonzalez-Bailon et al., 2011 to predict the occurrence of protests in three countries of Latin America: Brazil, Mexico, and Venezuela. The basic assumption is that the emergence of a suitably detected activity cascade is a precursor or a surrogate to a real protest event that will happen "on the ground." Our model supports the theoretical characterization of large cascades using spectral properties and uses properties of detected cascades to forecast events. Experimental results on many datasets, including the recent June 2013 protests in Brazil, demonstrate the effectiveness of our approach.

  8. "Meniscus Sign" to Identify the Lenticule Edge in Small-Incision Lenticule Extraction.

    Science.gov (United States)

    Titiyal, Jeewan S; Kaur, Manpreet; Brar, Anand S; Falera, Ruchita

    2018-06-01

    To describe our technique of lenticule edge identification in small-incision lenticule extraction using the "meniscus sign" to prevent lenticule misdissection. Femtosecond laser application for small-incision lenticule extraction was performed. A "double ring" was visible, signifying the edge of the cap cut (outer ring) and lenticule cut (inner ring). The anterior and posterior lamellar planes were delineated in 2 different directions. During creation of the posterior lamellar channel, the lenticule edge was slightly pushed away from the surgeon to create a gap between the inner ring (diameter of the lenticule cut) and the lenticule edge. The lenticule edge assumed a frilled wavy appearance, and the meniscus sign was observed as a gap between the lenticule edge and the inner ring. The meniscus-shaped gap served as a landmark to identify the lenticule edge, and the relationship between the frilled lenticule edge and surgical instruments further acted as a guide to identify the correct plane of dissection. This technique was successfully undertaken in 50 eyes of 25 patients. The meniscus sign was observed in all cases, and no case had cap lenticular adhesions. The meniscus sign helps to identify the lenticule edge and correct dissection planes and provides a visual landmark during the entire surgical procedure.

  9. Quantum Cascade Lasers Modulation and Applications

    Science.gov (United States)

    Luzhansky, Edward

    The mid-wave IR (MWIR) spectral band, extending from 3 to 5 microns, is considered to be a low loss atmospheric window. There are several spectral sub-bands with relatively low atmospheric attenuation in this region making it popular for various commercial and military applications. Relatively low thermal and solar background emissions, effective penetration through the natural and anthropogenic obscurants and eye safety add to the long list of advantages of MWIR wavelengths. Quantum Cascade Lasers are compact semiconductor devices capable of operating in MWIR spectrum. They are based on inter-subband transitions in a multiple-quantum-well (QW) hetero-structure, designed by means of band-structure engineering. The inter-subband nature of the optical transition has several key advantages. First, the emission wavelength is primarily a function of the QW thickness. This characteristic allows choosing well-understood and reliable semiconductors for the generation of light in a wavelength range of interest. Second, a cascade process in which tens of photons are generated per injected electron. This cascading process is behind the intrinsic high-power capabilities of QCLs. This dissertation is focused on modulation properties of Quantum Cascade Lasers. Both amplitude and phase/frequency modulations were studied including modulation bandwidth, modulation efficiency and chirp linearity. Research was consisted of the two major parts. In the first part we describe the theory of frequency modulation (FM) response of Distributed Feedback Quantum Cascade Lasers (DFB QCL). It includes cascading effect on the QCL's maximum modulation frequency. The "gain levering" effect for the maximum FM response of the two section QCLs was studied as well. In the second part of research we concentrated on the Pulse Position Amplitude Modulation of a single section QCL. The low complexity, low size, weight and power Mid-Wavelength Infra-Red optical communications transceiver concept is

  10. Bursting behaviours in cascaded stimulated Brillouin scattering

    International Nuclear Information System (INIS)

    Liu Zhan-Jun; He Xian-Tu; Zheng Chun-Yang; Wang Yu-Gang

    2012-01-01

    Stimulated Brillouin scattering is studied by numerically solving the Vlasov—Maxwell system. A cascade of stimulated Brillouin scattering can occur when a linearly polarized laser pulse propagates in a plasma. It is found that a stimulated Brillouin scattering cascade can reduce the scattering and increase the transmission of light, as well as introduce a bursting behaviour in the evolution of the laser-plasma interaction. The bursting time in the reflectivity is found to be less than half the ion acoustic period. The ion temperature can affect the stimulated Brillouin scattering cascade, which can repeat several times at low ion temperatures and can be completely eliminated at high ion temperatures. For stimulated Brillouin scattering saturation, higher-harmonic generation and wave—wave interaction of the excited ion acoustic waves can restrict the amplitude of the latter. In addition, stimulated Brillouin scattering cascade can restrict the amplitude of the scattered light. (physics of gases, plasmas, and electric discharges)

  11. Cascades on a stochastic pulse-coupled network

    Science.gov (United States)

    Wray, C. M.; Bishop, S. R.

    2014-09-01

    While much recent research has focused on understanding isolated cascades of networks, less attention has been given to dynamical processes on networks exhibiting repeated cascades of opposing influence. An example of this is the dynamic behaviour of financial markets where cascades of buying and selling can occur, even over short timescales. To model these phenomena, a stochastic pulse-coupled oscillator network with upper and lower thresholds is described and analysed. Numerical confirmation of asynchronous and synchronous regimes of the system is presented, along with analytical identification of the fixed point state vector of the asynchronous mean field system. A lower bound for the finite system mean field critical value of network coupling probability is found that separates the asynchronous and synchronous regimes. For the low-dimensional mean field system, a closed-form equation is found for cascade size, in terms of the network coupling probability. Finally, a description of how this model can be applied to interacting agents in a financial market is provided.

  12. BCDForest: a boosting cascade deep forest model towards the classification of cancer subtypes based on gene expression data.

    Science.gov (United States)

    Guo, Yang; Liu, Shuhui; Li, Zhanhuai; Shang, Xuequn

    2018-04-11

    The classification of cancer subtypes is of great importance to cancer disease diagnosis and therapy. Many supervised learning approaches have been applied to cancer subtype classification in the past few years, especially of deep learning based approaches. Recently, the deep forest model has been proposed as an alternative of deep neural networks to learn hyper-representations by using cascade ensemble decision trees. It has been proved that the deep forest model has competitive or even better performance than deep neural networks in some extent. However, the standard deep forest model may face overfitting and ensemble diversity challenges when dealing with small sample size and high-dimensional biology data. In this paper, we propose a deep learning model, so-called BCDForest, to address cancer subtype classification on small-scale biology datasets, which can be viewed as a modification of the standard deep forest model. The BCDForest distinguishes from the standard deep forest model with the following two main contributions: First, a named multi-class-grained scanning method is proposed to train multiple binary classifiers to encourage diversity of ensemble. Meanwhile, the fitting quality of each classifier is considered in representation learning. Second, we propose a boosting strategy to emphasize more important features in cascade forests, thus to propagate the benefits of discriminative features among cascade layers to improve the classification performance. Systematic comparison experiments on both microarray and RNA-Seq gene expression datasets demonstrate that our method consistently outperforms the state-of-the-art methods in application of cancer subtype classification. The multi-class-grained scanning and boosting strategy in our model provide an effective solution to ease the overfitting challenge and improve the robustness of deep forest model working on small-scale data. Our model provides a useful approach to the classification of cancer subtypes

  13. Framework for cascade size calculations on random networks

    Science.gov (United States)

    Burkholz, Rebekka; Schweitzer, Frank

    2018-04-01

    We present a framework to calculate the cascade size evolution for a large class of cascade models on random network ensembles in the limit of infinite network size. Our method is exact and applies to network ensembles with almost arbitrary degree distribution, degree-degree correlations, and, in case of threshold models, for arbitrary threshold distribution. With our approach, we shift the perspective from the known branching process approximations to the iterative update of suitable probability distributions. Such distributions are key to capture cascade dynamics that involve possibly continuous quantities and that depend on the cascade history, e.g., if load is accumulated over time. As a proof of concept, we provide two examples: (a) Constant load models that cover many of the analytically tractable casacade models, and, as a highlight, (b) a fiber bundle model that was not tractable by branching process approximations before. Our derivations cover the whole cascade dynamics, not only their steady state. This allows us to include interventions in time or further model complexity in the analysis.

  14. Dependence of radiation damage accumulation in iron on underlying models of displacement cascades and subsequent defect migration

    International Nuclear Information System (INIS)

    Souidi, A.; Becquart, C.S.; Domain, C.; Terentyev, D.; Malerba, L.; Calder, A.F.; Bacon, D.J.; Stoller, R.E.; Osetsky, Yu. N.; Hou, M.

    2006-01-01

    Groups of displacement cascades calculated independently with different simulation models and computer codes are compared on a statistical basis. The parameters used for this comparison are the number of Frenkel pairs (FP) produced, the percentages of vacancies and self-interstitial atoms (SIAs) in clusters, the spatial extent and the aspect ratio of the vacancies and the SIAs formed in each cascade. One group of cascades was generated in the binary collision approximation (BCA) and all others by full molecular dynamics (MD). The MD results differ primarily due to the empirical interatomic potentials used and, to some extent, in code strategies. Cascades were generated in simulation boxes at different initial equilibrium temperatures. Only modest differences in the predicted numbers of FP are observed, but the other cascade parameters may differ by more than 100%. The consequences of these differences on long-term cluster growth in a radiation environment are examined by means of object kinetic Monte Carlo (OKMC) simulations. These were repeated with three different parameterizations of SIA and SIA cluster mobility. The differences encompassed low to high mobility, one- and three-dimensional migration of clusters, and complete immobility of large clusters. The OKMC evolution was followed until 0.1 dpa was reached. With the range of OKMC parameters used, cluster populations after 0.1 dpa differ by orders of magnitude. Using the groups of cascades from different sources induced no difference larger than a factor of 2 in the OKMC results. No correlation could be identified between the cascade parameters considered and the number densities of vacancies and SIAs predicted by OKMC to cluster in the long term. However, use of random point defect distributions instead of those obtained for displacement cascades as input for the OKMC modeling led to significantly different results. It is therefore suggested that although the displacement cascade characteristics considered

  15. Calculation and comparison with experimental data of cascade curves for liquid xenon

    International Nuclear Information System (INIS)

    Strugal'skij, Z.S.; Yablonskij, Z.

    1975-01-01

    Cascade curves calculated by different methods are compared with the experimental data for showers caused by gamma-quanta with the energies from 40 to 2000 MeV in liquid xenon. The minimum energy of shower electrons (cut-off energy) taken into account by the experiment amounts to 3.1-+1.2 MeV, whereas the calculated cascade curves are given for the energies ranging from 40 to 4000 MeV at the cut-off energies 2.3; 3.5; 4.7 MeV. The depth of the shower development is reckoned from the point of generation of gamma-quanta which create showers. Cascade curves are calculated by the moment method with consideration for three moments. The following physical processes are taken into consideration: generation of electron-positron pairs; Compton effect; bremsstrahlung; ionization losses. The dependences of the mean number of particles on the depth of the shower development are obtained from measurements of photographs taken with a xenon bubble chamber. Presented are similar dependences calculated by the moment and Monte-Carlo methods. From the data analysis it follows that the calculation provides correct position of the shower development maximum, but different methods of calculation for small and low depths of shower development yield drastically different results. The Monte-Carlo method provides better agreement with the experimental data

  16. Small Worldness in Dense and Weighted Connectomes

    Science.gov (United States)

    Colon-Perez, Luis; Couret, Michelle; Triplett, William; Price, Catherine; Mareci, Thomas

    2016-05-01

    The human brain is a heterogeneous network of connected functional regions; however, most brain network studies assume that all brain connections can be described in a framework of binary connections. The brain is a complex structure of white matter tracts connected by a wide range of tract sizes, which suggests a broad range of connection strengths. Therefore, the assumption that the connections are binary yields an incomplete picture of the brain. Various thresholding methods have been used to remove spurious connections and reduce the graph density in binary networks. But these thresholds are arbitrary and make problematic the comparison of networks created at different thresholds. The heterogeneity of connection strengths can be represented in graph theory by applying weights to the network edges. Using our recently introduced edge weight parameter, we estimated the topological brain network organization using a complimentary weighted connectivity framework to the traditional framework of a binary network. To examine the reproducibility of brain networks in a controlled condition, we studied the topological network organization of a single healthy individual by acquiring 10 repeated diffusion-weighted magnetic resonance image datasets, over a one-month period on the same scanner, and analyzing these networks with deterministic tractography. We applied a threshold to both the binary and weighted networks and determined that the extra degree of freedom that comes with the framework of weighting network connectivity provides a robust result as any threshold level. The proposed weighted connectivity framework provides a stable result and is able to demonstrate the small world property of brain networks in situations where the binary framework is inadequate and unable to demonstrate this network property.

  17. Mesoporous silica-encapsulated gold nanoparticles as artificial enzymes for self-activated cascade catalysis.

    Science.gov (United States)

    Lin, Youhui; Li, Zhenhua; Chen, Zhaowei; Ren, Jinsong; Qu, Xiaogang

    2013-04-01

    A significant challenge in chemistry is to create synthetic structures that mimic the complexity and function of natural systems. Here, a self-activated, enzyme-mimetic catalytic cascade has been realized by utilizing expanded mesoporous silica-encapsulated gold nanoparticles (EMSN-AuNPs) as both glucose oxidase- and peroxidase-like artificial enzymes. Specifically, EMSN helps the formation of a high degree of very small and well-dispersed AuNPs, which exhibit an extraordinarily stability and dual enzyme-like activities. Inspired by these unique and attractive properties, we further piece them together into a self-organized artificial cascade reaction, which is usually completed by the oxidase-peroxidase coupled enzyme system. Our finding may pave the way to use matrix as the structural component for the design and development of biomimetic catalysts and to apply enzyme mimics for realizing higher functions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Increasing sensitivity of MOS dosemeters in cascade connection

    International Nuclear Information System (INIS)

    Vychytil, F.; Cechak, T.; Gerndt, J.; Petr, I.

    1978-01-01

    The possibilities of increasing the sensitivity of MOS transistors in their cascade connection were studied theoretically and experimentally. The measurements confirmed the presumption that the instability of cascade-connected MOS transistors increased with the square of the number of transistors in the system. This allows systems to be formed with different sensitivity to ionizing radiation by encasing 10 to 10 4 transistors connected in cascade, which is technologically feasible. The procedure is also acceptable from the point of view of cost. (Z.M.)

  19. Evaluation of refrigerating and air-conditioning technologies in heat cascading systems under the carbon dioxide emissions constraint: the proposal of the energy cascade balance table

    International Nuclear Information System (INIS)

    Shimazaki, Yoichi

    2003-01-01

    The aim of this study was to evaluate the refrigerating and air-conditioning technologies in cases of introducing both heat cascading systems and thermal recycling systems in industries located around urban areas. It is necessary to introduce heat cascading systems in the industrial sector in Japan to reduce carbon dioxide emissions. The concept of heat cascading is the multi-stage use of thermal energy by temperature level. This paper introduces three energy policies for introducing the heat cascading systems. The author develops an energy cascade model based on linear programming so as to minimize the total system costs with carbon taxes. Five cases are investigated. Carbon dioxide emission constraints result in the enhancement of heat cascading, where high temperature heat is supplied for process heating while low temperature heat is shifted to refrigeration. It was found that increasing the amount of garbage combustion waste heat could reduce electric power for the turbo compression refrigerator by promoting waste heat driven ammonia absorption refrigerator. In addition, this study proposes an energy cascade balance table with respect to the temperature level

  20. On the trajectories of CRL...LR...R orbits, their period-doubling cascades and saddle-node bifurcation cascades

    International Nuclear Information System (INIS)

    Cerrada, Lucia; San Martin, Jesus

    2011-01-01

    In this Letter, it is shown that from a two region partition of the phase space of a one-dimensional dynamical system, a p-region partition can be obtained for the CRL...LR...R orbits. That is, permutations associated with symbolic sequences are obtained. As a consequence, the trajectory in phase space is directly deduced from permutation. From this permutation other permutations associated with period-doubling and saddle-node bifurcation cascades are derived, as well as other composite permutations. - Research highlights: → Symbolic sequences are the usual topological approach to dynamical systems. → Permutations bear more physical information than symbolic sequences. → Period-doubling cascade permutations associated with original sequences are obtained. → Saddle-node cascade permutations associated with original sequences are obtained. → Composite permutations are derived.

  1. Development of a New Cascade Voltage-Doubler for Voltage Multiplication

    OpenAIRE

    Toudeshki, Arash; Mariun, Norman; Hizam, Hashim; Abdul Wahab, Noor Izzri

    2014-01-01

    For more than eight decades, cascade voltage-doubler circuits are used as a method to produce DC output voltage higher than the input voltage. In this paper, the topological developments of cascade voltage-doublers are reviewed. A new circuit configuration for cascade voltage-doubler is presented. This circuit can produce a higher value of the DC output voltage and better output quality compared to the conventional cascade voltage-doubler circuits, with the same number of stages.

  2. A Novel Concept for Three-Phase Cascaded Multilevel Inverter Topologies

    Directory of Open Access Journals (Sweden)

    Md Mubashwar Hasan

    2018-01-01

    Full Text Available One of the key challenges in multilevel inverters (MLIs design is to reduce the number of components used in the implementation while maximising the number of output voltage levels. This paper proposes a new concept that facilitates a device count reduction technique of existing cascaded MLIs. Moreover, the proposed concept can be utilised to extend existing single phase cascaded MLI topologies to three-phase structure without tripling the number of semiconductor components and input dc-supplies as per the current practice. The new generalized concept involves two stages; namely, cascaded stage and phase generator stage. The phase generator stage is a combination of a conventional three-phase two level inverter and three bi-directional switches while the cascaded stage can employ any existing cascaded topology. A laboratory prototype model is built and extensive experimental analyses are conducted to validate the feasibility of the proposed cascaded MLI concept.

  3. Molecular dynamics simulation of displacement cascades in iron-alpha

    International Nuclear Information System (INIS)

    Vascon, R.

    1997-01-01

    Radiation damage by neutrons or ions in bcc iron has been investigated by molecular dynamics simulations using an embedded atom type many-body potential (EAM). Displacement cascades with energies of 1 to 30 keV were generated in the microcanonical system where the number of atoms (up to 1.5 million) is chosen high enough to compensate the fact that the dissipation of energy is not taken into account in our model. The defect number at the end of cascade lifetime was found to be 60 percent of the NRT standard value. This tendency is in good agreement with experimental data. However, compared with other simulations in iron, we found significant differences in the defect production and distribution. The comparison with results obtained form simulations of cascades in other metals, leads on the one hand to a higher value of the defect number in bcc iron than in fcc metals like copper or nickel, and on the other hand to a ratio, between the number of replacements and the number of defects, lower in iron ( 100). We observed the transient melting of the core of the cascade during simulations. We showed that a higher value of the initial iron crystal temperature, as the mass difference between the components of an artificial binary alloy Fe-X(X=Al,Sb,Au,U) both produce a 'cascade effect': a decrease of the number of defects and an increase of the number of replacements. We also showed up the quasi-channeling of some atoms in high energy cascades. They are at the origin of sub-cascades formation; as a result they induce an opposite effect to the 'cascade effect'. (author)

  4. [Problems resulting from the absorption of small towns into urban areas in major Third World cities].

    Science.gov (United States)

    Mckee, D L

    1985-01-01

    The tendency toward hypertrophy of large metropolitan areas in the Third World has been a subject of concern to economists and other social scientists for some time. Inability to absorb vast waves of migrants into the organized labor force or to provide adequate infrastructure and services are serious problems in many growing cities of Asia, Africa, and Latin America. A different phenomenon created by perpetual urban expansion has been relatively neglected: the problems caused when preexisting urban areas are absorbed into the metropolis. The tendency of squatter settlements to constrict normal urban growth and expansion and to impede rational provision of services has been recognized, but the absorption of small cities does not necessarily produce identical problems. Small cities absorbed into a metropolis lose their identity in the successive waves of suburban proliferation. Los Angeles in the US may be considered the prototype of the phenomenon in which multiple preexisting urban zones are absorbed into the same metropolis without formation of any visible center of gravity. In some cases, small cities may be completely engulfed by the encroaching metropolis, if transit routes or availability of land makes them interesting to developers. The livelihood of residents may be threatened if they are no longer able to cultivate gardens or raise small animals. Local services may deteriorate. The youngest and most able residents are likely to abandon such places for the greater opportunities of the city, leaving the aged and less qualified to fend for themselves. Jobs may disappear and traditional commercial relations may be destroyed without being replaced. The future wellbeing of residents depends on their ability to maneuver in the new metropolitan environment, but many will be unable to adjust for lack of training, the weight of immovable property, or diverse personal considerations. Planning could help to reduce the problems that occasional survival of some small

  5. Design concept of Hydro cascade control system

    International Nuclear Information System (INIS)

    Fustik, Vangel; Kiteva, Nevenka

    2006-01-01

    In this paper a design concept of the comple hydro cascade scheme is presented with the design parameters of the main technical features. The cascade control system architecture is designed considering up-to-date communication and information technology. The control algorithm is based on Pond Level Control and Economic Load Allocation concepts.

  6. On calculating of squared-off cascades for multicomponent isotope separation

    International Nuclear Information System (INIS)

    Potapov, D.V.; Soulaberidze, G.A.; Chuzhinov, V.A.; Filipppov, I.G.

    1996-01-01

    Calculation on a cascade of specified configuration (specified number of stages and flows in the enriching and stripping sections of the cascade) is performed with two approaches. The first one, which is advisable to use for for calculation of so-called 'long' cascades (for example, squared-off cascades of distillation columns), is based on either analytical transitions enabling the problem to be reduced to to the algebraic transcendental equations, or based on the direct integration of the equations describing the cascade separation process, with the subsequent iteration on the boundary conditions and the balance equations. This approach also involves the orthogonal-collocation technique consisting in the approximation of the differential equations solution by an Lagrangian polynomial interpolation

  7. Sample Selection for Training Cascade Detectors.

    Science.gov (United States)

    Vállez, Noelia; Deniz, Oscar; Bueno, Gloria

    2015-01-01

    Automatic detection systems usually require large and representative training datasets in order to obtain good detection and false positive rates. Training datasets are such that the positive set has few samples and/or the negative set should represent anything except the object of interest. In this respect, the negative set typically contains orders of magnitude more images than the positive set. However, imbalanced training databases lead to biased classifiers. In this paper, we focus our attention on a negative sample selection method to properly balance the training data for cascade detectors. The method is based on the selection of the most informative false positive samples generated in one stage to feed the next stage. The results show that the proposed cascade detector with sample selection obtains on average better partial AUC and smaller standard deviation than the other compared cascade detectors.

  8. The temporal development of collision cascades in the binary collision approximation

    International Nuclear Information System (INIS)

    Robinson, M.T.

    1989-07-01

    A modified binary collision approximation (BCA) was developed to allow explicit evaluation of the times at which projectiles in a collision cascade reach significant points in their trajectories, without altering the ''event-driven'' character of the model. The modified BCA was used to study the temporal development of cascades in copper and gold, initiated by primary atoms of up to 10 keV initial kinetic energy. Cascades generated with time-ordered collisions show fewer ''distant'' Frenkel pairs than do cascades generated with velocity-ordered collisions. In the former, the slower projectiles tend to move in less-damaged crystal than they do in the latter. The effect is larger in Au than in Cu and increases with primary energy. As an approach to cascade nonlinearities, cascades were generated in which stopped cascade atoms were allowed to be redisplaced in later encounters. There were many more redisplacements in time-ordered cascades than in velocity-ordered ones. Because of the additional stopping introduced by the redisplacement events, the cascades in which they were allowed had fewer defects than occurred otherwise. This effect also was larger in Au than in Cu and larger at high energies although most of the redisplacement encounters involved only low-energy particles. 13 refs., 5 figs., 4 tabs

  9. Long-term scheduling of large cascade hydropower stations in Jinsha River, China

    International Nuclear Information System (INIS)

    Wang, Chao; Zhou, Jianzhong; Lu, Peng; Yuan, Liu

    2015-01-01

    Highlights: • Proposing a Gaussian group selection strategy to overcome premature convergence. • Multi-population ant are developed to enhance the search ability. • Proposing a circulatory solution correction to handle constraints. • Numerical and real hydropower system simulation are used to verify its performance. • Compensation analysis has been done to large hydropower stations in Jinsha River. - Abstract: The Jinsha River is the third longest river in the world. It consists of four large hydropower stations with total installed capacity 42,960 MW lying on the upper stretches of the Yangtze River, which is the longest river in the word. Due to the great potential of large cascade hydropower stations on power generation, long-term scheduling of large cascade hydropower stations (LSLCHS) plays an important role in electrical power system. As more and more concentrations focused on the optimal operation of large cascade hydropower stations, the LSLCHS has been taken into a multi-dimensional, non-convex and non-linear optimization problem due to its complicated hydraulic connection relationships and varieties of complex constraints with considering its power generation, shipping and ecological characteristics. In order to solve this problem, a multi-population ant colony optimization for continuous domain (MACO R ) is proposed in this paper. A Gaussian group selection strategy is applied to overcome premature convergence and ants with different characteristics are employed to enhance search ability, and circulatory solution correction strategy is presented to handle outflow, water level and output constraints. Furthermore, the efficiency and stability of MACO R are verified by its more desirable results in comparison to other latest works in numerical simulation, and it can be a viable alternative for solving those complicated optimal problems. With the applications in hydropower operation, LSLCHS can obtain more power generation benefit than other

  10. All passive architecture for high efficiency cascaded Raman conversion

    Science.gov (United States)

    Balaswamy, V.; Arun, S.; Chayran, G.; Supradeepa, V. R.

    2018-02-01

    Cascaded Raman fiber lasers have offered a convenient method to obtain scalable, high-power sources at various wavelength regions inaccessible with rare-earth doped fiber lasers. A limitation previously was the reduced efficiency of these lasers. Recently, new architectures have been proposed to enhance efficiency, but this came at the cost of enhanced complexity, requiring an additional low-power, cascaded Raman laser. In this work, we overcome this with a new, all-passive architecture for high-efficiency cascaded Raman conversion. We demonstrate our architecture with a fifth-order cascaded Raman converter from 1117nm to 1480nm with output power of ~64W and efficiency of 60%.

  11. Minimum Entropy-Based Cascade Control for Governing Hydroelectric Turbines

    Directory of Open Access Journals (Sweden)

    Mifeng Ren

    2014-06-01

    Full Text Available In this paper, an improved cascade control strategy is presented for hydroturbine speed governors. Different from traditional proportional-integral-derivative (PID control and model predictive control (MPC strategies, the performance index of the outer controller is constructed by integrating the entropy and mean value of the tracking error with the constraints on control energy. The inner controller is implemented by a proportional controller. Compared with the conventional PID-P and MPC-P cascade control methods, the proposed cascade control strategy can effectively decrease fluctuations of hydro-turbine speed under non-Gaussian disturbance conditions in practical hydropower plants. Simulation results show the advantages of the proposed cascade control method.

  12. SmallWorld Behavior of the Worldwide Active Volcanoes Network: Preliminary Results

    Science.gov (United States)

    Spata, A.; Bonforte, A.; Nunnari, G.; Puglisi, G.

    2009-12-01

    We propose a preliminary complex networks based approach in order to model and characterize volcanoes activity correlation observed on a planetary scale over the last two thousand years. Worldwide volcanic activity is in fact related to the general plate tectonics that locally drives the faults activity, that in turn controls the magma upraise beneath the volcanoes. To find correlations among different volcanoes could indicate a common underlying mechanism driving their activity and could help us interpreting the deeper common dynamics controlling their unrest. All the first evidences found testing the procedure, suggest the suitability of this analysis to investigate global volcanism related to plate tectonics. The first correlations found, in fact, indicate that an underlying common large-scale dynamics seems to drive volcanic activity at least around the Pacific plate, where it collides and subduces beneath American, Eurasian and Australian plates. From this still preliminary analysis, also more complex relationships among volcanoes lying on different tectonic margins have been found, suggesting some more complex interrelationships between different plates. The understanding of eventually detected correlations could be also used to further implement warning systems, relating the unrest probabilities of a specific volcano also to the ongoing activity to the correlated ones. Our preliminary results suggest that, as for other many physical and biological systems, an underlying organizing principle of planetary volcanoes activity might exist and it could be a small-world principle. In fact we found that, from a topological perspective, volcanoes correlations are characterized by the typical features of small-world network: a high clustering coefficient and a low characteristic path length. These features confirm that global volcanoes activity is characterized by both short and long-range correlations. We stress here the fact that numerical simulation carried out in

  13. Space-time evolution of electron cascades in diamond

    International Nuclear Information System (INIS)

    Ziaja, Beata; Szoeke, Abraham; Spoel, David van der; Hajdu, Janos

    2002-01-01

    The impact of a primary electron initiates a cascade of secondary electrons in solids, and these cascades play a significant role in the dynamics of ionization. Here we describe model calculations to follow the spatiotemporal evolution of secondary electron cascades in diamond. The band structure of the insulator has been explicitly incorporated into the calculations as it affects ionizations from the valence band. A Monte Carlo model was constructed to describe the path of electrons following the impact of a single electron of energy E∼250 eV. This energy is similar to the energy of an Auger electron from carbon. Two limiting cases were considered: the case in which electrons transmit energy to the lattice, and the case where no such energy transfer is permitted. The results show the evolution of the secondary electron cascades in terms of the number of electrons liberated, the spatial distribution of these electrons, and the energy distribution among the electrons as a function of time. The predicted ionization rates (∼5-13 electrons in 100 fs) lie within the limits given by experiments and phenomenological models. Calculation of the local electron density and the corresponding Debye length shows that the latter is systematically larger than the radius of the electron cloud, and it increases exponentially with the radial size of the cascade. This means that the long-range Coulomb field is not shielded within this cloud, and the electron gas generated does not represent a plasma in a single impact cascade triggered by an electron of E∼250 eV energy. This is important as it justifies the independent-electron approximation used in the model. At 1 fs, the (average) spatial distribution of secondary electrons is anisotropic with the electron cloud elongated in the direction of the primary impact. The maximal radius of the cascade is about 50 A at this time. At 10 fs the cascade has a maximal radius of ∼70 A, and is already dominated by low-energy electrons

  14. Energy cascading in the beat-wave accelerator

    International Nuclear Information System (INIS)

    McKinstrie, C.J.; Batha, S.H.

    1987-01-01

    A review is given of energy cascading in the beat-wave accelerator. The properties of the electromagnetic cascade and the corresponding plasma-wave evolution are well understood within the framework of an approximate analytic model. Based on this model, idealized laser-plasma coupling efficiencies of the order of 10% do not seem unreasonable. 28 refs

  15. Simulation of short-term annealing of displacement cascades in FCC metals

    International Nuclear Information System (INIS)

    Heinisch, H.L.; Doran, D.G.; Schwartz, D.M.

    1980-01-01

    Computer models have been developed for the simulation of high energy displacement cascades. The objective is the generation of defect production functions for use in correlation analysis of radiation effects in fusion reactor materials. In particular, the stochastic cascade annealing simulation code SCAS has been developed and used to model the short-term annealing behavior of simulated cascades in FCC metals. The code is fast enough to make annealing of high energy cascades practical. Sets of cascades from 5 keV to 100 keV in copper were generated by the binary collision code MARLOWE

  16. Giant Planets: Good Neighbors for Habitable Worlds?

    Science.gov (United States)

    Georgakarakos, Nikolaos; Eggl, Siegfried; Dobbs-Dixon, Ian

    2018-04-01

    The presence of giant planets influences potentially habitable worlds in numerous ways. Massive celestial neighbors can facilitate the formation of planetary cores and modify the influx of asteroids and comets toward Earth analogs later on. Furthermore, giant planets can indirectly change the climate of terrestrial worlds by gravitationally altering their orbits. Investigating 147 well-characterized exoplanetary systems known to date that host a main-sequence star and a giant planet, we show that the presence of “giant neighbors” can reduce a terrestrial planet’s chances to remain habitable, even if both planets have stable orbits. In a small fraction of systems, however, giant planets slightly increase the extent of habitable zones provided that the terrestrial world has a high climate inertia. In providing constraints on where giant planets cease to affect the habitable zone size in a detrimental fashion, we identify prime targets in the search for habitable worlds.

  17. A cascade of warming impacts brings bluefin tuna to Greenland waters

    DEFF Research Database (Denmark)

    MacKenzie, Brian; Payne, Mark; Boje, Jesper

    Rising ocean temperatures are causing marine fish species to shift spatial distributions and ranges, and are altering predator-prey dynamics in food-webs. Most documented cases of species shifts so far involve relatively small species at lower trophic levels, and consider individual species...... since 1985, when temperatures began to rise. The presence of bluefin tuna in this region is likely due to a combination of warm temperatures that are physiologically more tolerable and immigration of an important prey species into the region. We conclude that a cascade of climate change impacts...

  18. Congestion and cascades in payment systems

    Science.gov (United States)

    Beyeler, Walter E.; Glass, Robert J.; Bech, Morten L.; Soramäki, Kimmo

    2007-10-01

    We develop a parsimonious model of the interbank payment system. The model incorporates an endogenous instruction arrival process, a scale-free topology of payments between banks, a fixed total liquidity which limits banks’ capacity to process arriving instructions, and a global market that distributes liquidity. We find that at low liquidity the system becomes congested and payment settlement loses correlation with payment instruction arrival, becoming coupled across the network. The onset of congestion is evidently related to the relative values of three characteristic times: the time for banks’ net position to return to 0, the time for a bank to exhaust its liquidity endowment, and the liquidity market relaxation time. In the congested regime settlement takes place in cascades having a characteristic length scale. A global liquidity market substantially attenuates congestion, requiring only a small fraction of the payment-induced liquidity flow to achieve strong beneficial effects.

  19. Allozyme and microsatellite data reveal small clone size and high genetic diversity in aspen in the southern Cascade Mountains

    Science.gov (United States)

    Jennifer DeWoody; Thomas H. Rickman; Bobette E. Jones; Valerie D. Hipkins

    2009-01-01

    The most widely distributed tree in North America, quaking aspen (Populus tremuloides, Michx.), reproduces sexually via seed and clonally via suckers. The size of aspen clones varies geographically, generally smaller in the east and large in the arid Intermountain West. In order to describe clone size and genetic structure of aspen in the southern Cascade...

  20. Interictal to Ictal Phase Transition in a Small-World Network

    Science.gov (United States)

    Nemzer, Louis; Cravens, Gary; Worth, Robert

    Real-time detection and prediction of seizures in patients with epilepsy is essential for rapid intervention. Here, we perform a full Hodgkin-Huxley calculation using n 50 in silico neurons configured in a small-world network topology to generate simulated EEG signals. The connectivity matrix, constructed using a Watts-Strogatz algorithm, admits randomized or deterministic entries. We find that situations corresponding to interictal (non-seizure) and ictal (seizure) states are separated by a phase transition that can be influenced by congenital channelopathies, anticonvulsant drugs, and connectome plasticity. The interictal phase exhibits scale-free phenomena, as characterized by a power law form of the spectral power density, while the ictal state suffers from pathological synchronization. We compare the results with intracranial EEG data and show how these findings may be used to detect or even predict seizure onset. Along with the balance of excitatory and inhibitory factors, the network topology plays a large role in determining the overall characteristics of brain activity. We have developed a new platform for testing the conditions that contribute to the phase transition between non-seizure and seizure states.

  1. Optimization of the cascade with gas centrifuges for uranium enrichment

    International Nuclear Information System (INIS)

    Ozaki, N.; Harada, I.

    1976-01-01

    Computer programs to optimize the step and tapered-step cascades with gas centrifuges are developed. The 'Complex Method', one of the direct search method, is employed to find the optimum of the nonlinear function of several variables within a constrained region. The separation characteristics of the optimized step and tapered-step cascades are discussed in comparison with that of the ideal cascade. The local optima of the cascade profile, the convergence of the object function, and the stopping criterion for the optimization trial are also discussed. (author)

  2. Centrifugal separator cascade connected in zigzag manner

    International Nuclear Information System (INIS)

    Kai, Tsunetoshi; Inoue, Yoshiya; Oya, Akio; Nagakura, Masaaki.

    1974-01-01

    Object: To effectively accommodate centrifugal separators of the entire cascade within the available space in a plant by freely selecting perpendicular direction of connection of the centrifugal separator. Structure: Centrifugal separators are connected in zigzag fashion by using a single header for each stage so that in a rectangular shape the entire cascade is arranged. (Kamimura, M.)

  3. A period-doubling cascade precedes chaos for planar maps.

    Science.gov (United States)

    Sander, Evelyn; Yorke, James A

    2013-09-01

    A period-doubling cascade is often seen in numerical studies of those smooth (one-parameter families of) maps for which as the parameter is varied, the map transitions from one without chaos to one with chaos. Our emphasis in this paper is on establishing the existence of such a cascade for many maps with phase space dimension 2. We use continuation methods to show the following: under certain general assumptions, if at one parameter there are only finitely many periodic orbits, and at another parameter value there is chaos, then between those two parameter values there must be a cascade. We investigate only families that are generic in the sense that all periodic orbit bifurcations are generic. Our method of proof in showing there is one cascade is to show there must be infinitely many cascades. We discuss in detail two-dimensional families like those which arise as a time-2π maps for the Duffing equation and the forced damped pendulum equation.

  4. Sample Selection for Training Cascade Detectors.

    Directory of Open Access Journals (Sweden)

    Noelia Vállez

    Full Text Available Automatic detection systems usually require large and representative training datasets in order to obtain good detection and false positive rates. Training datasets are such that the positive set has few samples and/or the negative set should represent anything except the object of interest. In this respect, the negative set typically contains orders of magnitude more images than the positive set. However, imbalanced training databases lead to biased classifiers. In this paper, we focus our attention on a negative sample selection method to properly balance the training data for cascade detectors. The method is based on the selection of the most informative false positive samples generated in one stage to feed the next stage. The results show that the proposed cascade detector with sample selection obtains on average better partial AUC and smaller standard deviation than the other compared cascade detectors.

  5. Multilevel Inverter by Cascading Industrial VSI

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Blaabjerg, Frede; Pedersen, John Kim

    2002-01-01

    In this paper the modularity concept applied to medium-voltage adjustable speed drives is addressed. First, the single-phase cascaded voltage-source inverter that uses series connection of IGBT H-bridge modules with isolated dc-buses is presented. Next, a novel three-phase cascaded voltage......-source inverter that uses three IGBT triphase inverter modules along with an output transformer to obtain a 3 p.u. multilevel output voltage is introduced. The system yields in high-quality multistep voltage with up to 4 levels and low dv/dt, balanced operation of the inverter modules, each supplying a third...... of the motor rated kVA. The concept of using cascaded inverters is further extended to a new modular motor-modular inverter system where the motor winding connections are reconnected into several three-phase groups, either six-lead or 12-lead connection according to the voltage level, each powered...

  6. Particle fluxes in atomic collision cascades

    International Nuclear Information System (INIS)

    Sckerl, B.W.; Sigmund, P.; Vicanek, M.

    1996-01-01

    The flux of recoil atoms in atomic collision cascades induced by an ion beam or another source of energetic particles in a material is known to approach isotropy at kinetic energies far below the beam energy. A variety of irradiation effects can be explained satisfactorily on the basis of an isotropic particle flux, but significant deviations from this simple behavior are known to exist. While numerous examples have been studied by numerical simulation of cascade processes, the systematics is, by and large, unknown. The present study aims at general scaling properties and estimates of the magnitude of moderate deviations from isotropy and their spatial dependence for a wide range of beam and material parameters. Anisotropies introduced by crystal structure are ignored. Although it is well established that cascade anisotropy is related to the momentum of beam particles, previous attempts to quantify this relation have failed. We have found that there are two leading correction terms to the isotropic particle flux, a well-known term centered around the beam direction as a symmetry axis and a new term proportional to the gradient of the deposited-energy density. As a general rule the two contributions are either both significant or both negligible. Specific situations in which the gradient term dominates are, however, of considerable interest in applications. The parameters which characterize the anisotropy of collision cascades also determine the deposition of momentum, but the connection is less straightforward than asserted hitherto. General principles are first illustrated on the specific case of elastic-collision cascades under self-bombardment which contains the essentials. Thereafter several generalizations are made, including atomic binding forces and inelasticity as well as allowance for multicomponent materials. Application areas in mixing and sputtering are outlined. (au) 58 refs

  7. Cascading Generative Adversarial Networks for Targeted

    KAUST Repository

    Hamdi, Abdullah

    2018-01-01

    Abundance of labelled data played a crucial role in the recent developments in computer vision, but that faces problems like scalability and transferability to the wild. One alternative approach is to utilize the data without labels, i.e. unsupervised learning, in learning valuable information and put it in use to tackle vision problems. Generative Adversarial Networks (GANs) have gained momentum for their ability to model image distributions in unsupervised manner. They learn to emulate the training set and that enables sampling from that domain and using the knowledge learned for useful applications. Several methods proposed enhancing GANs, including regularizing the loss with some feature matching. We seek to push GANs beyond the data in the training and try to explore unseen territory in the image manifold. We first propose a new regularizer for GAN based on K-Nearest Neighbor (K-NN) selective feature matching to a target set Y in high-level feature space, during the adversarial training of GAN on the base set X, and we call this novel model K-GAN. We show that minimizing the added term follows from cross-entropy minimization between the distributions of GAN and set Y. Then, we introduce a cascaded framework for GANs that try to address the task of imagining a new distribution that combines the base set X and target set Y by cascading sampling GANs with translation GANs, and we dub the cascade of such GANs as the Imaginative Adversarial Network (IAN). Several cascades are trained on a collected dataset Zoo-Faces and generated innovative samples are shown, including from K-GAN cascade. We conduct an objective and subjective evaluation for different IAN setups in the addressed task of generating innovative samples and we show the effect of regularizing GAN on different scores. We conclude with some useful applications for these IANs, like multi-domain manifold traversing.

  8. Cascading Generative Adversarial Networks for Targeted

    KAUST Repository

    Hamdi, Abdullah

    2018-04-09

    Abundance of labelled data played a crucial role in the recent developments in computer vision, but that faces problems like scalability and transferability to the wild. One alternative approach is to utilize the data without labels, i.e. unsupervised learning, in learning valuable information and put it in use to tackle vision problems. Generative Adversarial Networks (GANs) have gained momentum for their ability to model image distributions in unsupervised manner. They learn to emulate the training set and that enables sampling from that domain and using the knowledge learned for useful applications. Several methods proposed enhancing GANs, including regularizing the loss with some feature matching. We seek to push GANs beyond the data in the training and try to explore unseen territory in the image manifold. We first propose a new regularizer for GAN based on K-Nearest Neighbor (K-NN) selective feature matching to a target set Y in high-level feature space, during the adversarial training of GAN on the base set X, and we call this novel model K-GAN. We show that minimizing the added term follows from cross-entropy minimization between the distributions of GAN and set Y. Then, we introduce a cascaded framework for GANs that try to address the task of imagining a new distribution that combines the base set X and target set Y by cascading sampling GANs with translation GANs, and we dub the cascade of such GANs as the Imaginative Adversarial Network (IAN). Several cascades are trained on a collected dataset Zoo-Faces and generated innovative samples are shown, including from K-GAN cascade. We conduct an objective and subjective evaluation for different IAN setups in the addressed task of generating innovative samples and we show the effect of regularizing GAN on different scores. We conclude with some useful applications for these IANs, like multi-domain manifold traversing.

  9. Establishment and evaluation of operation function model for cascade hydropower station

    OpenAIRE

    Chang-ming Ji; Ting Zhou; Hai-tao Huang

    2010-01-01

    Toward solving the actual operation problems of cascade hydropower stations under hydrologic uncertainty, this paper presents the process of extraction of statistical characteristics from long-term optimal cascade operation, and proposes a monthly operation function algorithm for the actual operation of cascade hydropower stations through the identification, processing, and screening of available information during long-term optimal operation. Applying the operation function to the cascade hy...

  10. Predatory fishes affect trophic cascades and apparent competition in temperate reefs.

    Science.gov (United States)

    Frid, Alejandro; Marliave, Jeff

    2010-08-23

    We provide evidence for a trophic cascade involving apex predators and mesopredators of marine temperate reefs, lingcod and rockfish, respectively. We measured spatio-temporal variation in the relative abundance of lingcod, subadult rockfish and two shrimp groups eaten by rockfish (Pandalus sp. and three smaller-bodied genera aggregated). Lingcod had an indirect positive effect on shrimps, as mediated by the direct negative effects of lingcod on rockfish and of rockfish on shrimps. These top-down effects on shrimps, however, were stronger for Pandalus than for small-bodied shrimps. Further, abundances of Pandalus and small-bodied shrimps were negatively correlated and the latter had a stronger positive effect on rockfish, suggesting that rockfish mediated asymmetrical apparent competition between shrimps. Our results indicate mechanisms by which predatory fishes may influence the structure of marine communities.

  11. Ericksen number and Deborah number cascade predictions of a model for liquid crystalline polymers for simple shear flow

    Science.gov (United States)

    Klein, D. Harley; Leal, L. Gary; García-Cervera, Carlos J.; Ceniceros, Hector D.

    2007-02-01

    We consider the behavior of the Doi-Marrucci-Greco (DMG) model for nematic liquid crystalline polymers in planar shear flow. We found the DMG model to exhibit dynamics in both qualitative and quantitative agreement with experimental observations reported by Larson and Mead [Liq. Cryst. 15, 151 (1993)] for the Ericksen number and Deborah number cascades. For increasing shear rates within the Ericksen number cascade, the DMG model displays three distinct regimes: stable simple shear, stable roll cells, and irregular structure accompanied by disclination formation. In accordance with experimental observations, the model predicts both ±1 and ±1/2 disclinations. Although ±1 defects form via the ridge-splitting mechanism first identified by Feng, Tao, and Leal [J. Fluid Mech. 449, 179 (2001)], a new mechanism is identified for the formation of ±1/2 defects. Within the Deborah number cascade, with increasing Deborah number, the DMG model exhibits a streamwise banded texture, in the absence of disclinations and roll cells, followed by a monodomain wherein the mean orientation lies within the shear plane throughout the domain.

  12. Displacement cascades and defect annealing in tungsten, Part II: Object kinetic Monte Carlo simulation of tungsten cascade aging

    Energy Technology Data Exchange (ETDEWEB)

    Nandipati, Giridhar, E-mail: giridhar.nandipati@pnnl.gov [Pacific Northwest National Laboratory, Richland, WA (United States); Setyawan, Wahyu; Heinisch, Howard L. [Pacific Northwest National Laboratory, Richland, WA (United States); Roche, Kenneth J. [Pacific Northwest National Laboratory, Richland, WA (United States); Department of Physics, University of Washington, Seattle, WA 98195 (United States); Kurtz, Richard J. [Pacific Northwest National Laboratory, Richland, WA (United States); Wirth, Brian D. [University of Tennessee, Knoxville, TN (United States)

    2015-07-15

    The results of object kinetic Monte Carlo (OKMC) simulations of the annealing of primary cascade damage in bulk tungsten using a comprehensive database of cascades obtained from molecular dynamics (Setyawan et al.) are described as a function of primary knock-on atom (PKA) energy at temperatures of 300, 1025 and 2050 K. An increase in SIA clustering coupled with a decrease in vacancy clustering with increasing temperature, in addition to the disparate mobilities of SIAs versus vacancies, causes an interesting effect of temperature on cascade annealing. The annealing efficiency (the ratio of the number of defects after and before annealing) exhibits an inverse U-shape curve as a function of temperature. The capabilities of the newly developed OKMC code KSOME (kinetic simulations of microstructure evolution) used to carry out these simulations are described.

  13. Displacement cascades and defect annealing in tungsten, Part II: Object kinetic Monte Carlo Simulation of Tungsten Cascade Aging

    Energy Technology Data Exchange (ETDEWEB)

    Nandipati, Giridhar; Setyawan, Wahyu; Heinisch, Howard L.; Roche, Kenneth J.; Kurtz, Richard J.; Wirth, Brian D.

    2015-07-01

    The results of object kinetic Monte Carlo (OKMC) simulations of the annealing of primary cascade damage in bulk tungsten using a comprehensive database of cascades obtained from molecular dynamics (Setyawan et al.) are described as a function of primary knock-on atom (PKA) energy at temperatures of 300, 1025 and 2050 K. An increase in SIA clustering coupled with a decrease in vacancy clustering with increasing temperature, in addition to the disparate mobilities of SIAs versus vacancies, causes an interesting effect of temperature on cascade annealing. The annealing efficiency (the ratio of the number of defects after and before annealing) exhibits an inverse U-shape curve as a function of temperature. The capabilities of the newly developed OKMC code KSOME (kinetic simulations of microstructure evolution) used to carry out these simulations are described.

  14. Sign epistasis caused by hierarchy within signalling cascades.

    Science.gov (United States)

    Nghe, Philippe; Kogenaru, Manjunatha; Tans, Sander J

    2018-04-13

    Sign epistasis is a central evolutionary constraint, but its causal factors remain difficult to predict. Here we use the notion of parameterised optima to explain epistasis within a signalling cascade, and test these predictions in Escherichia coli. We show that sign epistasis arises from the benefit of tuning phenotypic parameters of cascade genes with respect to each other, rather than from their complex and incompletely known genetic bases. Specifically, sign epistasis requires only that the optimal phenotypic parameters of one gene depend on the phenotypic parameters of another, independent of other details, such as activating or repressing nature, position within the cascade, intra-genic pleiotropy or genotype. Mutational effects change sign more readily in downstream genes, indicating that optimising downstream genes is more constrained. The findings show that sign epistasis results from the inherent upstream-downstream hierarchy between signalling cascade genes, and can be addressed without exhaustive genotypic mapping.

  15. Synchronizations in small-world networks of spiking neurons: Diffusive versus sigmoid couplings

    International Nuclear Information System (INIS)

    Hasegawa, Hideo

    2005-01-01

    By using a semianalytical dynamical mean-field approximation previously proposed by the author [H. Hasegawa, Phys. Rev. E 70, 066107 (2004)], we have studied the synchronization of stochastic, small-world (SW) networks of FitzHugh-Nagumo neurons with diffusive couplings. The difference and similarity between results for diffusive and sigmoid couplings have been discussed. It has been shown that with introducing the weak heterogeneity to regular networks, the synchronization may be slightly increased for diffusive couplings, while it is decreased for sigmoid couplings. This increase in the synchronization for diffusive couplings is shown to be due to their local, negative feedback contributions, but not due to the short average distance in SW networks. Synchronization of SW networks depends not only on their structure but also on the type of couplings

  16. A Single Session of rTMS Enhances Small-Worldness in Writer’s Cramp: Evidence from Simultaneous EEG-fMRI Multi-Modal Brain Graph

    Directory of Open Access Journals (Sweden)

    Rose D. Bharath

    2017-09-01

    Full Text Available Background and Purpose: Repetitive transcranial magnetic stimulation (rTMS induces widespread changes in brain connectivity. As the network topology differences induced by a single session of rTMS are less known we undertook this study to ascertain whether the network alterations had a small-world morphology using multi-modal graph theory analysis of simultaneous EEG-fMRI.Method: Simultaneous EEG-fMRI was acquired in duplicate before (R1 and after (R2 a single session of rTMS in 14 patients with Writer’s Cramp (WC. Whole brain neuronal and hemodynamic network connectivity were explored using the graph theory measures and clustering coefficient, path length and small-world index were calculated for EEG and resting state fMRI (rsfMRI. Multi-modal graph theory analysis was used to evaluate the correlation of EEG and fMRI clustering coefficients.Result: A single session of rTMS was found to increase the clustering coefficient and small-worldness significantly in both EEG and fMRI (p < 0.05. Multi-modal graph theory analysis revealed significant modulations in the fronto-parietal regions immediately after rTMS. The rsfMRI revealed additional modulations in several deep brain regions including cerebellum, insula and medial frontal lobe.Conclusion: Multi-modal graph theory analysis of simultaneous EEG-fMRI can supplement motor physiology methods in understanding the neurobiology of rTMS in vivo. Coinciding evidence from EEG and rsfMRI reports small-world morphology for the acute phase network hyper-connectivity indicating changes ensuing low-frequency rTMS is probably not “noise”.

  17. Current redistribution in resistor networks: Fat-tail statistics in regular and small-world networks.

    Science.gov (United States)

    Lehmann, Jörg; Bernasconi, Jakob

    2017-03-01

    The redistribution of electrical currents in resistor networks after single-bond failures is analyzed in terms of current-redistribution factors that are shown to depend only on the topology of the network and on the values of the bond resistances. We investigate the properties of these current-redistribution factors for regular network topologies (e.g., d-dimensional hypercubic lattices) as well as for small-world networks. In particular, we find that the statistics of the current redistribution factors exhibits a fat-tail behavior, which reflects the long-range nature of the current redistribution as determined by Kirchhoff's circuit laws.

  18. A thermal modelling of displacement cascades in uranium dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Martin, G., E-mail: guillaume.martin@cea.fr [CEA – DEN/DEC/SESC/LLCC, Bât. 352, 13108 Saint-Paul-Lez-Durance Cedex (France); Garcia, P.; Sabathier, C. [CEA – DEN/DEC/SESC/LLCC, Bât. 352, 13108 Saint-Paul-Lez-Durance Cedex (France); Devynck, F.; Krack, M. [Laboratory for Reactor Physics and Systems Behaviour, Paul Scherrer Institute, CH-5232 Villigen PSI (Switzerland); Maillard, S. [CEA – DEN/DEC/SESC/LLCC, Bât. 352, 13108 Saint-Paul-Lez-Durance Cedex (France)

    2014-05-01

    The space and time dependent temperature distribution was studied in uranium dioxide during displacement cascades simulated by classical molecular dynamics (MD). The energy for each simulated radiation event ranged between 0.2 keV and 20 keV in cells at initial temperatures of 700 K or 1400 K. Spheres into which atomic velocities were rescaled (thermal spikes) have also been simulated by MD to simulate the thermal excitation induced by displacement cascades. Equipartition of energy was shown to occur in displacement cascades, half of the kinetic energy of the primary knock-on atom being converted after a few tenths of picoseconds into potential energy. The kinetic and potential parts of the system energy are however subjected to little variations during dedicated thermal spike simulations. This is probably due to the velocity rescaling process, which impacts a large number of atoms in this case and would drive the system away from a dynamical equilibrium. This result makes questionable MD simulations of thermal spikes carried out up to now (early 2014). The thermal history of cascades was compared to the heat equation solution of a punctual thermal excitation in UO{sub 2}. The maximum volume brought to a temperature above the melting temperature during the simulated cascade events is well reproduced by this simple model. This volume eventually constitutes a relevant estimate of the volume affected by a displacement cascade in UO{sub 2}. This definition of the cascade volume could also make sense in other materials, like iron.

  19. Heterogeneous delay-induced asynchrony and resonance in a small-world neuronal network system

    Science.gov (United States)

    Yu, Wen-Ting; Tang, Jun; Ma, Jun; Yang, Xianqing

    2016-06-01

    A neuronal network often involves time delay caused by the finite signal propagation time in a given biological network. This time delay is not a homogenous fluctuation in a biological system. The heterogeneous delay-induced asynchrony and resonance in a noisy small-world neuronal network system are numerically studied in this work by calculating synchronization measure and spike interval distribution. We focus on three different delay conditions: double-values delay, triple-values delay, and Gaussian-distributed delay. Our results show the following: 1) the heterogeneity in delay results in asynchronous firing in the neuronal network, and 2) maximum synchronization could be achieved through resonance given that the delay values are integer or half-integer times of each other.

  20. A sulfur hexafluoride sensor using quantum cascade and CO2 laser-based photoacoustic spectroscopy.

    Science.gov (United States)

    Rocha, Mila; Sthel, Marcelo; Lima, Guilherme; da Silva, Marcelo; Schramm, Delson; Miklós, András; Vargas, Helion

    2010-01-01

    The increase in greenhouse gas emissions is a serious environmental problem and has stimulated the scientific community to pay attention to the need for detection and monitoring of gases released into the atmosphere. In this regard, the development of sensitive and selective gas sensors has been the subject of several research programs. An important greenhouse gas is sulphur hexafluoride, an almost non-reactive gas widely employed in industrial processes worldwide. Indeed it is estimated that it has a radiative forcing of 0.52 W/m(2). This work compares two photoacoustic spectrometers, one coupled to a CO(2) laser and another one coupled to a Quantum Cascade (QC) laser, for the detection of SF(6). The laser photoacoustic spectrometers described in this work have been developed for gas detection at small concentrations. Detection limits of 20 ppbv for CO(2) laser and 50 ppbv for quantum cascade laser were obtained.

  1. Criticality safety study of shutdown diffusion cascade coolers

    International Nuclear Information System (INIS)

    Paschal, L.S.; Basoglu, B.; Bentley, C.L.; Dunn, M.E.

    1996-01-01

    Gaseous diffusion plants use cascade coolers in the production of highly enriched uranium (HEU) to remove heat from the enriched stream of UF 6 . The cascade coolers operate like shell and tube heat exchangers with the UF 6 on the shell side and Freon on the tube side. Recirculating cooling water (RCW) in condensers is used to cool the Freon. A criticality safety analysis was previously performed for cascade coolers during normal operation. The purpose of this paper is to evaluate several different hypothetical accidents regarding RCW ingress into the cooler to determine whether criticality safety concerns exist

  2. Positional information generated by spatially distributed signaling cascades.

    Directory of Open Access Journals (Sweden)

    Javier Muñoz-García

    2009-03-01

    Full Text Available The temporal and stationary behavior of protein modification cascades has been extensively studied, yet little is known about the spatial aspects of signal propagation. We have previously shown that the spatial separation of opposing enzymes, such as a kinase and a phosphatase, creates signaling activity gradients. Here we show under what conditions signals stall in the space or robustly propagate through spatially distributed signaling cascades. Robust signal propagation results in activity gradients with long plateaus, which abruptly decay at successive spatial locations. We derive an approximate analytical solution that relates the maximal amplitude and propagation length of each activation profile with the cascade level, protein diffusivity, and the ratio of the opposing enzyme activities. The control of the spatial signal propagation appears to be very different from the control of transient temporal responses for spatially homogenous cascades. For spatially distributed cascades where activating and deactivating enzymes operate far from saturation, the ratio of the opposing enzyme activities is shown to be a key parameter controlling signal propagation. The signaling gradients characteristic for robust signal propagation exemplify a pattern formation mechanism that generates precise spatial guidance for multiple cellular processes and conveys information about the cell size to the nucleus.

  3. Global Search of a Three-dimensional Low Solidity Circular Cascade Diffuser for Centrifugal Blowers by Meta-model Assisted Optimization

    Science.gov (United States)

    Sakaguchi, Daisaku; Sakue, Daiki; Tun, Min Thaw

    2018-04-01

    A three-dimensional blade of a low solidity circular cascade diffuser in centrifugal blowers is designed by means of a multi-point optimization technique. The optimization aims at improving static pressure coefficient at a design point and at a small flow rate condition. Moreover, a clear definition of secondary flow expressed by positive radial velocity at hub side is taken into consideration in constraints. The number of design parameters for three-dimensional blade reaches to 10 in this study, such as a radial gap, a radial chord length and mean camber angle distribution of the LSD blade with five control points, control point between hub and shroud with two design freedom. Optimization results show clear Pareto front and selected optimum design shows good improvement of pressure rise in diffuser at small flow rate conditions. It is found that three-dimensional blade has advantage to stabilize the secondary flow effect with improving pressure recovery of the low solidity circular cascade diffuser.

  4. The flow analysis of supercavitating cascade by linear theory

    Energy Technology Data Exchange (ETDEWEB)

    Park, E.T. [Sung Kyun Kwan Univ., Seoul (Korea, Republic of); Hwang, Y. [Seoul National Univ., Seoul (Korea, Republic of)

    1996-06-01

    In order to reduce damages due to cavitation effects and to improve performance of fluid machinery, supercavitation around the cascade and the hydraulic characteristics of supercavitating cascade must be analyzed accurately. And the study on the effects of cavitation on fluid machinery and analysis on the performances of supercavitating hydrofoil through various elements governing flow field are critically important. In this study comparison of experiment results with the computed results of linear theory using singularity method was obtainable. Specially singularity points like sources and vortexes on hydrofoil and freestreamline were distributed to analyze two dimensional flow field of supercavitating cascade, and governing equations of flow field were derived and hydraulic characteristics of cascade were calculated by numerical analysis of the governing equations. 7 refs., 6 figs.

  5. Computer simulation of high energy displacement cascades

    International Nuclear Information System (INIS)

    Heinisch, H.L.

    1990-01-01

    A methodology developed for modeling many aspects of high energy displacement cascades with molecular level computer simulations is reviewed. The initial damage state is modeled in the binary collision approximation (using the MARLOWE computer code), and the subsequent disposition of the defects within a cascade is modeled with a Monte Carlo annealing simulation (the ALSOME code). There are few adjustable parameters, and none are set to physically unreasonable values. The basic configurations of the simulated high energy cascades in copper, i.e., the number, size and shape of damage regions, compare well with observations, as do the measured numbers of residual defects and the fractions of freely migrating defects. The success of these simulations is somewhat remarkable, given the relatively simple models of defects and their interactions that are employed. The reason for this success is that the behavior of the defects is very strongly influenced by their initial spatial distributions, which the binary collision approximation adequately models. The MARLOWE/ALSOME system, with input from molecular dynamics and experiments, provides a framework for investigating the influence of high energy cascades on microstructure evolution. (author)

  6. Influence of non-binary effects on intranuclear cascade method

    International Nuclear Information System (INIS)

    Gomes, E.H.C.

    1985-01-01

    The importance of non binary process effects in the intranuclear cascade method is analysed. It is shown that, in the higher density steps, the non binary collisions lead to baryon density distribution and rapidity differents from the one obtained using the usual intranuclear cascade method (limited to purely binary collisions). The validity of the applications of binary intranuclear cascade method to the simulation of the thermal equilibrium, nuclear transparency and particle production, is discussed. (M.C.K.) [pt

  7. Revealing the structure of the world airline network

    Science.gov (United States)

    Verma, T.; Araújo, N. A. M.; Herrmann, H. J.

    2014-07-01

    Resilience of most critical infrastructures against failure of elements that appear insignificant is usually taken for granted. The World Airline Network (WAN) is an infrastructure that reduces the geographical gap between societies, both small and large, and brings forth economic gains. With the extensive use of a publicly maintained data set that contains information about airports and alternative connections between these airports, we empirically reveal that the WAN is a redundant and resilient network for long distance air travel, but otherwise breaks down completely due to removal of short and apparently insignificant connections. These short range connections with moderate number of passengers and alternate flights are the connections that keep remote parts of the world accessible. It is surprising, insofar as there exists a highly resilient and strongly connected core consisting of a small fraction of airports (around 2.3%) together with an extremely fragile star-like periphery. Yet, in spite of their relevance, more than 90% of the world airports are still interconnected upon removal of this core. With standard and unconventional removal measures we compare both empirical and topological perceptions for the fragmentation of the world. We identify how the WAN is organized into different classes of clusters based on the physical proximity of airports and analyze the consequence of this fragmentation.

  8. Tunable signal processing in synthetic MAP kinase cascades.

    Science.gov (United States)

    O'Shaughnessy, Ellen C; Palani, Santhosh; Collins, James J; Sarkar, Casim A

    2011-01-07

    The flexibility of MAPK cascade responses enables regulation of a vast array of cell fate decisions, but elucidating the mechanisms underlying this plasticity is difficult in endogenous signaling networks. We constructed insulated mammalian MAPK cascades in yeast to explore how intrinsic and extrinsic perturbations affect the flexibility of these synthetic signaling modules. Contrary to biphasic dependence on scaffold concentration, we observe monotonic decreases in signal strength as scaffold concentration increases. We find that augmenting the concentration of sequential kinases can enhance ultrasensitivity and lower the activation threshold. Further, integrating negative regulation and concentration variation can decouple ultrasensitivity and threshold from the strength of the response. Computational analyses show that cascading can generate ultrasensitivity and that natural cascades with different kinase concentrations are innately biased toward their distinct activation profiles. This work demonstrates that tunable signal processing is inherent to minimal MAPK modules and elucidates principles for rational design of synthetic signaling systems. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. Invertebrates of The H.J. Andrews Experimental Forest, Western Cascades, Oregon: I. An annotated checklist of fleas.

    Science.gov (United States)

    Robert E. Lewis; Chris Maser

    1981-01-01

    During a trapping survey of small mammals (approximately 3,000 individuals), species of fleas (1,632 specimens) were collected in the H.J. Andrews Experimental Forest, Western Cascades, Oregon. Host mammals were represented by 15 species—6 insectivores and 9 rodents captured from June through September. The collections extend our knowledge of the fauna of Oregon.

  10. Small-worldness and gender differences of large scale brain metabolic covariance networks in young adults: a FDG PET study of 400 subjects.

    Science.gov (United States)

    Hu, Yuxiao; Xu, Qiang; Shen, Junkang; Li, Kai; Zhu, Hong; Zhang, Zhiqiang; Lu, Guangming

    2015-02-01

    Many studies have demonstrated the small-worldness of the human brain, and have revealed a sexual dimorphism in brain network properties. However, little is known about the gender effects on the topological organization of the brain metabolic covariance networks. To investigate the small-worldness and the gender differences in the topological architectures of human brain metabolic networks. FDG-PET data of 400 healthy right-handed subjects (200 women and 200 age-matched men) were involved in the present study. Metabolic networks of each gender were constructed by calculating the covariance of regional cerebral glucose metabolism (rCMglc) across subjects on the basis of AAL parcellation. Gender differences of network and nodal properties were investigated by using the graph theoretical approaches. Moreover, the gender-related difference of rCMglc in each brain region was tested for investigating the relationships between the hub regions and the brain regions showing significant gender-related differences in rCMglc. We found prominent small-world properties in the domain of metabolic networks in each gender. No significant gender difference in the global characteristics was found. Gender differences of nodal characteristic were observed in a few brain regions. We also found bilateral and lateralized distributions of network hubs in the females and males. Furthermore, we first reported that some hubs of a gender located in the brain regions showing weaker rCMglc in this gender than the other gender. The present study demonstrated that small-worldness was existed in metabolic networks, and revealed gender differences of organizational patterns in metabolic network. These results maybe provided insights into the understanding of the metabolic substrates underlying individual differences in cognition and behaviors. © The Foundation Acta Radiologica 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  11. Usefulness of virtual images of the visceral pleura in identifying the localization of peripheral small pulmonary nodules intraoperatively

    International Nuclear Information System (INIS)

    Kambayashi, Takatoyo

    2011-01-01

    The objective of this study was to assess the usefulness of virtual images of the visceral pleura in identifying the localization of peripheral small pulmonary nodules intraoperatively. We examined 12 cases with 12 peripheral small pulmonary nodules between 2008 and 2010. All lesions were predicted to be difficult to identify during surgery, and virtual images of the visceral pleura were made and evaluated before surgery. We predicted the usefulness of virtual images of the visceral pleura in identifying the localization of peripheral small pulmonary nodules. The mean maximum dimensions were 10.5±4.36 mm. The mean depth from the visceral pleura was 4.0±4.67 mm. The lesions were the solid type in 6 cases and the ground-glass opacity type in 6 cases. In 7 cases primary lung cancer was present, while the other 5 cases had only benign lesions. In all cases, changes in the visceral pleura could be identified with virtual images of the visceral pleura before surgery. We identified 7 lesions out of 12 intraoperatively. The reasons for the failure to identify the lesions were an inability to adequately observe the visceral pleura because of pleural adhesion, or failure to perform single lung ventilation in 3 cases. Another reason was that the changes in the visceral pleura were too minor to identify intraoperatively (2 cases). Virtual images of the visceral pleura may be useful for identifying the localization of peripheral small pulmonary nodules, and the prediction of whether or not the identification of lesions is possible intraoperatively, without preoperative marking in order to identify peripheral pulmonary nodules. (author)

  12. Cascade ICF power reactor

    International Nuclear Information System (INIS)

    Hogan, W.J.; Pitts, J.H.

    1986-01-01

    The double-cone-shaped Cascade reaction chamber rotates at 50 rpm to keep a blanket of ceramic granules in place against the wall as they slide from the poles to the exit slots at the equator. The 1 m-thick blanket consists of layers of carbon, beryllium oxide, and lithium aluminate granules about 1 mm in diameter. The x rays and debris are stopped in the carbon granules; the neutrons are multiplied and moderated in the BeO and breed tritium in the LiAlO 2 . The chamber wall is made up of SiO tiles held in compression by a network of composite SiC/Al tendons. Cascade operates at a 5 Hz pulse rate with 300 MJ in each pulse. The temperature in the blanket reaches 1600 K on the inner surface and 1350 K at the outer edge. The granules are automatically thrown into three separate vacuum heat exchangers where they give up their energy to high pressure helium. The helium is used in a Brayton cycle to obtain a thermal-to-electric conversion efficiency of 55%. Studies have been done on neutron activation, debris recovery, vaporization and recondensation of blanket material, tritium control and recovery, fire safety, and cost. These studies indicate that Cascade appears to be a promising ICF reactor candidate from all standpoints. At the 1000 MWe size, electricity could be made for about the same cost as in a future fission reactor

  13. Cascading Failures and Recovery in Networks of Networks

    Science.gov (United States)

    Havlin, Shlomo

    Network science have been focused on the properties of a single isolated network that does not interact or depends on other networks. In reality, many real-networks, such as power grids, transportation and communication infrastructures interact and depend on other networks. I will present a framework for studying the vulnerability and the recovery of networks of interdependent networks. In interdependent networks, when nodes in one network fail, they cause dependent nodes in other networks to also fail. This is also the case when some nodes like certain locations play a role in two networks -multiplex. This may happen recursively and can lead to a cascade of failures and to a sudden fragmentation of the system. I will present analytical solutions for the critical threshold and the giant component of a network of n interdependent networks. I will show, that the general theory has many novel features that are not present in the classical network theory. When recovery of components is possible global spontaneous recovery of the networks and hysteresis phenomena occur and the theory suggests an optimal repairing strategy of system of systems. I will also show that interdependent networks embedded in space are significantly more vulnerable compared to non embedded networks. In particular, small localized attacks may lead to cascading failures and catastrophic consequences.Thus, analyzing data of real network of networks is highly required to understand the system vulnerability. DTRA, ONR, Israel Science Foundation.

  14. A cascading failure model for analyzing railway accident causation

    Science.gov (United States)

    Liu, Jin-Tao; Li, Ke-Ping

    2018-01-01

    In this paper, a new cascading failure model is proposed for quantitatively analyzing the railway accident causation. In the model, the loads of nodes are redistributed according to the strength of the causal relationships between the nodes. By analyzing the actual situation of the existing prevention measures, a critical threshold of the load parameter in the model is obtained. To verify the effectiveness of the proposed cascading model, simulation experiments of a train collision accident are performed. The results show that the cascading failure model can describe the cascading process of the railway accident more accurately than the previous models, and can quantitatively analyze the sensitivities and the influence of the causes. In conclusion, this model can assist us to reveal the latent rules of accident causation to reduce the occurrence of railway accidents.

  15. Cascade Structure of Digital Predistorter for Power Amplifier Linearization

    Directory of Open Access Journals (Sweden)

    E. B. Solovyeva

    2015-12-01

    Full Text Available In this paper, a cascade structure of nonlinear digital predistorter (DPD synthesized by the direct learning adaptive algorithm is represented. DPD is used for linearization of power amplifier (PA characteristic, namely for compensation of PA nonlinear distortion. Blocks of the cascade DPD are described by different models: the functional link artificial neural network (FLANN, the polynomial perceptron network (PPN and the radially pruned Volterra model (RPVM. At synthesis of the cascade DPD there is possibility to overcome the ill conditionality problem due to reducing the dimension of DPD nonlinear operator approximation. Results of compensating nonlinear distortion in Wiener–Hammerstein model of PA at the GSM–signal with four carriers are shown. The highest accuracy of PA linearization is produced by the cascade DPD containing PPN and RPVM.

  16. Increase of transient lower esophageal sphincter relaxation associated with cascade stomach

    Science.gov (United States)

    Kawada, Akiyo; Kusano, Motoyasu; Hosaka, Hiroko; Kuribayashi, Shiko; Shimoyama, Yasuyuki; Kawamura, Osamu; Akiyama, Junichi; Yamada, Masanobu; Akuzawa, Masako

    2017-01-01

    We previously reported that cascade stomach was associated with reflux symptoms and esophagitis. Delayed gastric emptying has been believed to initiate transient lower esophageal sphincter relaxation (TLESR). We hypothesized that cascade stomach may be associated with frequent TLESR with delayed gastric emptying. Eleven subjects with cascade stomach and 11 subjects without cascade stomach were enrolled. Postprandial gastroesophageal manometry and gastric emptying using a continuous 13C breath system were measured simultaneously after a liquid test meal. TLESR events were counted in early period (0–60 min), late period (60–120 min), and total monitoring period. Three parameters of gastric emptying were calculated: the half emptying time, lag time, and gastric emptying coefficient. The median frequency of TLESR events in the cascade stomach and non-cascade stomach groups was 6.0 (median), 4.6 (interquartile range) vs 5.0, 3.0 in the early period, 5.0, 3.2 vs 3.0, 1.8 in the late period, and 10.0, 6.2 vs 8.0, 5.0 in the total monitoring period. TLESR events were significantly more frequent in the cascade stomach group during the late and total monitoring periods. In contrast, gastric emptying parameters showed no significant differences between the two groups. We concluded that TLESR events were significantly more frequent in persons with cascade stomach without delayed gastric emptying. PMID:28584403

  17. Networks of neuroblastoma cells on porous silicon substrates reveal a small world topology

    KAUST Repository

    Marinaro, Giovanni; La Rocca, Rosanna; Toma, Andrea; Barberio, Marianna; Cancedda, Laura; Di Fabrizio, Enzo M.; Decuzzi, Paolo C W; Gentile, Francesco T.

    2015-01-01

    The human brain is a tightly interweaving network of neural cells where the complexity of the network is given by the large number of its constituents and its architecture. The topological structure of neurons in the brain translates into its increased computational capabilities, low energy consumption, and nondeterministic functions, which differentiate human behavior from artificial computational schemes. In this manuscript, we fabricated porous silicon chips with a small pore size ranging from 8 to 75 nm and large fractal dimensions up to Df ∼ 2.8. In culturing neuroblastoma N2A cells on the described substrates, we found that those cells adhere more firmly to and proliferate on the porous surfaces compared to the conventional nominally flat silicon substrates, which were used as controls. More importantly, we observed that N2A cells on the porous substrates create highly clustered, small world topology patterns. We conjecture that neurons with a similar architecture may elaborate information more efficiently than in random or regular grids. Moreover, we hypothesize that systems of neurons on nano-scale geometry evolve in time to form networks in which the propagation of information is maximized. This journal is

  18. On peculiarities of the cascade γ decay of heavy nuclei

    International Nuclear Information System (INIS)

    Boneva, S.T.; Khitrov, V.A.; Popov, Yu.P.; Sukhovoj, A.M.; Vasil'eva, E.V.; Yazvitskij, Yu.S.

    1987-01-01

    Comparison of measured and calculated by statistical theory sums of two-quanta cascade intensities in compound-nuclei 163 ≤ A ≤ 183 points to the dependence of cascade intensity on the structure of initial and intermediate levels. The dependence of two-quanta cascade intensity sum on reduced neutron widths of compound states of even-even nuclei-targets of rare earth regions is detected. In 175 Yb and 179 Hf nuclei a considerable increase in the intensity of two-quanta cascades at the energy of their intermediate level in the range of the calculated position of one-quasiparticle states of the Saxon-Woods deformed potential is observed

  19. Designing the Cascade inertial confinement fusion reactor

    International Nuclear Information System (INIS)

    Pitts, J.H.

    1987-01-01

    The primary goal in designing inertial confinement fusion (ICF) reactors is to produce electrical power as inexpensively as possible, with minimum activation and without compromising safety. This paper discusses a method for designing the Cascade rotating ceramic-granule-blanket reactor (Pitts, 1985) and its associated power plant (Pitts and Maya, 1985). Although focus is on the cascade reactor, the design method and issues presented are applicable to most other ICF reactors

  20. Hadronic cascade processes

    International Nuclear Information System (INIS)

    Ilgenfritz, E.M.; Kripfganz, J.; Moehring, H.J.

    1977-01-01

    The analytical treatment of hadronic decay cascades within the framework of the statistical bootstrap model is demonstrated on the basis of a simple variant. Selected problems for a more comprehensive formulation of the model such as angular momentum conservation, quantum statistical effects, and the immediate applicability to particle production processes at high energies are discussed in detail

  1. INCAS: an analytical model to describe displacement cascades

    Energy Technology Data Exchange (ETDEWEB)

    Jumel, Stephanie E-mail: stephanie.jumel@edf.fr; Claude Van-Duysen, Jean E-mail: jean-claude.van-duysen@edf.fr

    2004-07-01

    REVE (REactor for Virtual Experiments) is an international project aimed at developing tools to simulate neutron irradiation effects in Light Water Reactor materials (Fe, Ni or Zr-based alloys). One of the important steps of the project is to characterise the displacement cascades induced by neutrons. Accordingly, the Department of Material Studies of Electricite de France developed an analytical model based on the binary collision approximation. This model, called INCAS (INtegration of CAScades), was devised to be applied on pure elements; however, it can also be used on diluted alloys (reactor pressure vessel steels, etc.) or alloys composed of atoms with close atomic numbers (stainless steels, etc.). INCAS describes displacement cascades by taking into account the nuclear collisions and electronic interactions undergone by the moving atoms. In particular, it enables to determine the mean number of sub-cascades induced by a PKA (depending on its energy) as well as the mean energy dissipated in each of them. The experimental validation of INCAS requires a large effort and could not be carried out in the framework of the study. However, it was verified that INCAS results are in conformity with those obtained from other approaches. As a first application, INCAS was applied to determine the sub-cascade spectrum induced in iron by the neutron spectrum corresponding to the central channel of the High Flux Irradiation Reactor of Oak Ridge National Laboratory.

  2. INCAS: an analytical model to describe displacement cascades

    Science.gov (United States)

    Jumel, Stéphanie; Claude Van-Duysen, Jean

    2004-07-01

    REVE (REactor for Virtual Experiments) is an international project aimed at developing tools to simulate neutron irradiation effects in Light Water Reactor materials (Fe, Ni or Zr-based alloys). One of the important steps of the project is to characterise the displacement cascades induced by neutrons. Accordingly, the Department of Material Studies of Electricité de France developed an analytical model based on the binary collision approximation. This model, called INCAS (INtegration of CAScades), was devised to be applied on pure elements; however, it can also be used on diluted alloys (reactor pressure vessel steels, etc.) or alloys composed of atoms with close atomic numbers (stainless steels, etc.). INCAS describes displacement cascades by taking into account the nuclear collisions and electronic interactions undergone by the moving atoms. In particular, it enables to determine the mean number of sub-cascades induced by a PKA (depending on its energy) as well as the mean energy dissipated in each of them. The experimental validation of INCAS requires a large effort and could not be carried out in the framework of the study. However, it was verified that INCAS results are in conformity with those obtained from other approaches. As a first application, INCAS was applied to determine the sub-cascade spectrum induced in iron by the neutron spectrum corresponding to the central channel of the High Flux Irradiation Reactor of Oak Ridge National Laboratory.

  3. INCAS: an analytical model to describe displacement cascades

    International Nuclear Information System (INIS)

    Jumel, Stephanie; Claude Van-Duysen, Jean

    2004-01-01

    REVE (REactor for Virtual Experiments) is an international project aimed at developing tools to simulate neutron irradiation effects in Light Water Reactor materials (Fe, Ni or Zr-based alloys). One of the important steps of the project is to characterise the displacement cascades induced by neutrons. Accordingly, the Department of Material Studies of Electricite de France developed an analytical model based on the binary collision approximation. This model, called INCAS (INtegration of CAScades), was devised to be applied on pure elements; however, it can also be used on diluted alloys (reactor pressure vessel steels, etc.) or alloys composed of atoms with close atomic numbers (stainless steels, etc.). INCAS describes displacement cascades by taking into account the nuclear collisions and electronic interactions undergone by the moving atoms. In particular, it enables to determine the mean number of sub-cascades induced by a PKA (depending on its energy) as well as the mean energy dissipated in each of them. The experimental validation of INCAS requires a large effort and could not be carried out in the framework of the study. However, it was verified that INCAS results are in conformity with those obtained from other approaches. As a first application, INCAS was applied to determine the sub-cascade spectrum induced in iron by the neutron spectrum corresponding to the central channel of the High Flux Irradiation Reactor of Oak Ridge National Laboratory

  4. Gradients in Catostomid assemblages along a reservoir cascade

    Science.gov (United States)

    Miranda, Leandro E.; Keretz, Kevin R.; Gilliland, Chelsea R.

    2017-01-01

    Serial impoundment of major rivers leads to alterations of natural flow dynamics and disrupts longitudinal connectivity. Catostomid fishes (suckers, family Catostomidae) are typically found in riverine or backwater habitats yet are able to persist in impounded river systems. To the detriment of conservation, there is limited information about distribution of catostomid fishes in impounded rivers. We examined the longitudinal distribution of catostomid fishes over 23 reservoirs of the Tennessee River reservoir cascade, encompassing approximately 1600 km. Our goal was to develop a basin-scale perspective to guide conservation efforts. Catostomid species composition and assemblage structure changed longitudinally along the reservoir cascade. Catostomid species biodiversity was greatest in reservoirs lower in the cascade. Assemblage composition shifted from dominance by spotted sucker Minytrema melanops and buffalos Ictiobus spp. in the lower reservoirs to carpsuckers Carpiodes spp. midway through the cascade and redhorses Moxostoma spp. in the upper reservoirs. Most species did not extend the length of the cascade, and some species were rare, found in low numbers and in few reservoirs. The observed gradients in catostomid assemblages suggest the need for basin-scale conservation measures focusing on three broad areas: (1) conservation and management of the up-lake riverine reaches of the lower reservoirs, (2) maintenance of the access to quality habitat in tributaries to the upper reservoirs and (3) reintroductions into currently unoccupied habitat within species' historic distributions

  5. DMH1, a small molecule inhibitor of BMP type i receptors, suppresses growth and invasion of lung cancer.

    Directory of Open Access Journals (Sweden)

    Jijun Hao

    Full Text Available The bone morphogenetic protein (BMP signaling cascade is aberrantly activated in human non-small cell lung cancer (NSCLC but not in normal lung epithelial cells, suggesting that blocking BMP signaling may be an effective therapeutic approach for lung cancer. Previous studies demonstrated that some BMP antagonists, which bind to extracellular BMP ligands and prevent their association with BMP receptors, dramatically reduced lung tumor growth. However, clinical application of protein-based BMP antagonists is limited by short half-lives, poor intra-tumor delivery as well as resistance caused by potential gain-of-function mutations in the downstream of the BMP pathway. Small molecule BMP inhibitors which target the intracellular BMP cascades would be ideal for anticancer drug development. In a zebrafish embryo-based structure and activity study, we previously identified a group of highly selective small molecule inhibitors specifically antagonizing the intracellular kinase domain of BMP type I receptors. In the present study, we demonstrated that DMH1, one of such inhibitors, potently reduced lung cell proliferation, promoted cell death, and decreased cell migration and invasion in NSCLC cells by blocking BMP signaling, as indicated by suppression of Smad 1/5/8 phosphorylation and gene expression of Id1, Id2 and Id3. Additionally, DMH1 treatment significantly reduced the tumor growth in human lung cancer xenograft model. In conclusion, our study indicates that small molecule inhibitors of BMP type I receptors may offer a promising novel strategy for lung cancer treatment.

  6. Identifying the Financial Literacy Skills Necessary to Run a Small New Zealand Business

    Science.gov (United States)

    Samkin, Grant; Pitu, Elizabeth; Low, Mary

    2014-01-01

    The objectives of this paper are to identify the financial skills small business owners believe necessary to be successful in business, and to establish whether there is a role for secondary school accounting in contributing to the learning of these skills. A combination of a social network website and snowball sampling technique was used to…

  7. Effects of partial time delays on phase synchronization in Watts-Strogatz small-world neuronal networks

    Science.gov (United States)

    Sun, Xiaojuan; Perc, Matjaž; Kurths, Jürgen

    2017-05-01

    In this paper, we study effects of partial time delays on phase synchronization in Watts-Strogatz small-world neuronal networks. Our focus is on the impact of two parameters, namely the time delay τ and the probability of partial time delay pdelay, whereby the latter determines the probability with which a connection between two neurons is delayed. Our research reveals that partial time delays significantly affect phase synchronization in this system. In particular, partial time delays can either enhance or decrease phase synchronization and induce synchronization transitions with changes in the mean firing rate of neurons, as well as induce switching between synchronized neurons with period-1 firing to synchronized neurons with period-2 firing. Moreover, in comparison to a neuronal network where all connections are delayed, we show that small partial time delay probabilities have especially different influences on phase synchronization of neuronal networks.

  8. Predicting the occurrence of channelized debris flow by an integrated cascading model: A case study of a small debris flow-prone catchment in Zhejiang Province, China

    Science.gov (United States)

    Wei, Zhen-lei; Xu, Yue-Ping; Sun, Hong-yue; Xie, Wei; Wu, Gang

    2018-05-01

    Excessive water in a channel is an important factor that triggers channelized debris flows. Floods and debris flows often occur in a cascading manner, and thus, calculating the amount of runoff accurately is important for predicting the occurrence of debris flows. In order to explore the runoff-rainfall relationship, we placed two measuring facilities at the outlet of a small, debris flow-prone headwater catchment to explore the hydrological response of the catchment. The runoff responses generally consisted of a rapid increase in runoff followed by a slower decrease. The peak runoff often occurred after the rainfall ended. The runoff discharge data were simulated by two different modeling approaches, i.e., the NAM model and the Hydrologic Engineering Center-Hydrologic Modeling System (HEC-HMS) model. The results showed that the NAM model performed better than the HEC-HMS model. The NAM model provided acceptable simulations, while the HEC-HMS model did not. Then, we coupled the calculated results of the NAM model with an empirically based debris flow initiation model to obtain a new integrated cascading disaster modeling system to provide improved disaster preparedness and hazard management. In this case study, we found that the coupled model could correctly predict the occurrence of debris flows. Furthermore, we evaluated the effect of the range of input parameter values on the hydrographical shape of the runoff. We also used the grey relational analysis to conduct a sensitivity analysis of the parameters of the model. This study highlighted the important connections between rainfall, hydrological processes, and debris flow, and it provides a useful prototype model system for operational forecasting of debris flows.

  9. Inverse Problem and Variation Method to Optimize Cascade Heat Exchange Network in Central Heating System

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yin; WEI Zhiyuan; ZHANG Yinping; WANG Xin

    2017-01-01

    Urban heating in northern China accounts for 40% of total building energy usage.In central heating systems,heat is often transfened from heat source to users by the heat network where several heat exchangers arc installed at heat source,substations and terminals respectively.For given overall heating capacity and heat source temperarure,increasing the terminal fluid temperature is an effective way to improve the thermal performance of such cascade heat exchange network for energy saving.In this paper,the mathematical optimization model of the cascade heat exchange network with three-stage heat exchangers in series is established.Aim at maximizing the cold fluid temperature for given hot fluid temperature and overall heating capacity,the optimal heat exchange area distribution and the medium fluids' flow rates are determined through inverse problem and variation method.The preliminary results show that the heat exchange areas should be distributed equally for each heat exchanger.It also indicates that in order to improve the thernmal performance of the whole system,more heat exchange areas should be allocated to the heat exchanger where flow rate difference between two fluids is relatively small.This work is important for guiding the optimization design of practical cascade heating systems.

  10. Quality of Care as an Emergent Phenomenon out of a Small-World Network of Relational Actors.

    Science.gov (United States)

    Fiorini, Rodolfo; De Giacomo, Piero; Marconi, Pier Luigi; L'Abate, Luciano

    2014-01-01

    In Healthcare Decision Support System, the development and evaluation of effective "Quality of Care" (QOC) indicators, in simulation-based training, are key feature to develop resilient and antifragile organization scenarios. Is it possible to conceive of QOC not only as a result of a voluntary and rational decision, imposed or even not, but also as an overall system "emergent phenomenon" out of a small-world network of relational synthetic actors, endowed with their own personality profiles to simulate human behaviour (for short, called "subjects")? In order to answer this question and to observe the phenomena of real emergence we should use computational models of high complexity, with heavy computational load and extensive computational time. Nevertheless, De Giacomo's Elementary Pragmatic Model (EPM) intrinsic self-reflexive functional logical closure enables to run simulation examples to classify the outcomes grown out of a small-world network of relational subjects fast and effectively. Therefore, it is possible to take note and to learn of how much strategic systemic interventions can induce context conditions of QOC facilitation, which can improve the effectiveness of specific actions, which otherwise might be paradoxically counterproductive also. Early results are so encouraging to use EPM as basic block to start designing more powerful Evolutive Elementary Pragmatic Model (E2PM) for real emergence computational model, to cope with ontological uncertainty at system level.

  11. A cascade of classifiers for extracting medication information from discharge summaries

    Directory of Open Access Journals (Sweden)

    Halgrim Scott

    2011-07-01

    Full Text Available Abstract Background Extracting medication information from clinical records has many potential applications, and recently published research, systems, and competitions reflect an interest therein. Much of the early extraction work involved rules and lexicons, but more recently machine learning has been applied to the task. Methods We present a hybrid system consisting of two parts. The first part, field detection, uses a cascade of statistical classifiers to identify medication-related named entities. The second part uses simple heuristics to link those entities into medication events. Results The system achieved performance that is comparable to other approaches to the same task. This performance is further improved by adding features that reference external medication name lists. Conclusions This study demonstrates that our hybrid approach outperforms purely statistical or rule-based systems. The study also shows that a cascade of classifiers works better than a single classifier in extracting medication information. The system is available as is upon request from the first author.

  12. Ambiguity of non-systematic chemical identifiers within and between small-molecule databases.

    Science.gov (United States)

    Akhondi, Saber A; Muresan, Sorel; Williams, Antony J; Kors, Jan A

    2015-01-01

    A wide range of chemical compound databases are currently available for pharmaceutical research. To retrieve compound information, including structures, researchers can query these chemical databases using non-systematic identifiers. These are source-dependent identifiers (e.g., brand names, generic names), which are usually assigned to the compound at the point of registration. The correctness of non-systematic identifiers (i.e., whether an identifier matches the associated structure) can only be assessed manually, which is cumbersome, but it is possible to automatically check their ambiguity (i.e., whether an identifier matches more than one structure). In this study we have quantified the ambiguity of non-systematic identifiers within and between eight widely used chemical databases. We also studied the effect of chemical structure standardization on reducing the ambiguity of non-systematic identifiers. The ambiguity of non-systematic identifiers within databases varied from 0.1 to 15.2 % (median 2.5 %). Standardization reduced the ambiguity only to a small extent for most databases. A wide range of ambiguity existed for non-systematic identifiers that are shared between databases (17.7-60.2 %, median of 40.3 %). Removing stereochemistry information provided the largest reduction in ambiguity across databases (median reduction 13.7 percentage points). Ambiguity of non-systematic identifiers within chemical databases is generally low, but ambiguity of non-systematic identifiers that are shared between databases, is high. Chemical structure standardization reduces the ambiguity to a limited extent. Our findings can help to improve database integration, curation, and maintenance.

  13. Searching for the most cost-effective strategy for controlling epidemics spreading on regular and small-world networks.

    Science.gov (United States)

    Kleczkowski, Adam; Oleś, Katarzyna; Gudowska-Nowak, Ewa; Gilligan, Christopher A

    2012-01-07

    We present a combined epidemiological and economic model for control of diseases spreading on local and small-world networks. The disease is characterized by a pre-symptomatic infectious stage that makes detection and control of cases more difficult. The effectiveness of local (ring-vaccination or culling) and global control strategies is analysed by comparing the net present values of the combined cost of preventive treatment and illness. The optimal strategy is then selected by minimizing the total cost of the epidemic. We show that three main strategies emerge, with treating a large number of individuals (global strategy, GS), treating a small number of individuals in a well-defined neighbourhood of a detected case (local strategy) and allowing the disease to spread unchecked (null strategy, NS). The choice of the optimal strategy is governed mainly by a relative cost of palliative and preventive treatments. If the disease spreads within the well-defined neighbourhood, the local strategy is optimal unless the cost of a single vaccine is much higher than the cost associated with hospitalization. In the latter case, it is most cost-effective to refrain from prevention. Destruction of local correlations, either by long-range (small-world) links or by inclusion of many initial foci, expands the range of costs for which the NS is most cost-effective. The GS emerges for the case when the cost of prevention is much lower than the cost of treatment and there is a substantial non-local component in the disease spread. We also show that local treatment is only desirable if the disease spreads on a small-world network with sufficiently few long-range links; otherwise it is optimal to treat globally. In the mean-field case, there are only two optimal solutions, to treat all if the cost of the vaccine is low and to treat nobody if it is high. The basic reproduction ratio, R(0), does not depend on the rate of responsive treatment in this case and the disease always invades

  14. Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.

    Directory of Open Access Journals (Sweden)

    David J Stanley

    2012-12-01

    Full Text Available Cellular restriction factors help to defend humans against human immunodeficiency virus (HIV. HIV accessory proteins hijack at least three different Cullin-RING ubiquitin ligases, which must be activated by the small ubiquitin-like protein NEDD8, in order to counteract host cellular restriction factors. We found that conjugation of NEDD8 to Cullin-5 by the NEDD8-conjugating enzyme UBE2F is required for HIV Vif-mediated degradation of the host restriction factor APOBEC3G (A3G. Pharmacological inhibition of the NEDD8 E1 by MLN4924 or knockdown of either UBE2F or its RING-protein binding partner RBX2 bypasses the effect of Vif, restoring the restriction of HIV by A3G. NMR mapping and mutational analyses define specificity determinants of the UBE2F NEDD8 cascade. These studies demonstrate that disrupting host NEDD8 cascades presents a novel antiretroviral therapeutic approach enhancing the ability of the immune system to combat HIV.

  15. A simple method for potential flow simulation of cascades

    Indian Academy of Sciences (India)

    vortex panel method to simulate potential flow in cascades is presented. The cascade ... The fluid loading on the blades, such as the normal force and pitching moment, may ... of such discrete infinite array singularities along the blade surface.

  16. Cascading of high salinity bottom waters from the Arabian/Persian Gulf to the northern Arabian Sea

    Science.gov (United States)

    Shapiro, Georgy; Wobus, Fred; Solovyev, Vladimir; Francis, Xavier; Hyder, Patrick; Chen, Feng; Asif, Muhammad

    2017-04-01

    Cascading (aka shelf convection) is a specific type of buoyancy driven current in which dense water is formed over the continental shelf and then descends down the slope to a greater depth. The cascades of dense water down continental slopes provide a mechanism for shelf-ocean exchange in many parts of the world's oceans (Shapiro et al, 2003). Dense water is formed on the shelf by a number of processes, with high evaporation, limited river discharge and low precipitation being the major processes in warm climates (Ivanov et al, 2004). The formation and outflow of high salinity waters in the near-bottom layer of the Arabian/Persian Gulf is an example of dense water cascading (Bower et al 2000). Despite of its importance for the self-cleaning and the state of the marine ecosystem in the Arabian/Persian Gulf, the properties of the outflow have so far mainly been analysed using climatologically averaged data or observations of a limited set of parameters (mainly temperature), see (Bower et al 2000). In this paper we study the dynamics of the flow using a comprehensive set of observational data (temperature, salinity velocity and turbidity profiles) obtained during the GRASP (Gulf Reconnaissance And Selective Profiling) observational campaign in the Gulf of Oman, which are complemented by the results of numerical modelling of the area using a number of 3D ocean models, and some ARGO T/S profiles. The GRASP measurements were carried out using an Aqualog climbing moored profiler, which was equipped with a Seabird CTD sensor, a Nortek Aquadopp current meter and a Seapoint turbidity meter. The Ocean circulation models used in the study include PGM4 and IND12 (UK Met Office); and AS20 and AG60 (University of Plymouth). All models are based on NEMO (Nucleus for European Modelling of the Ocean) codebase with a resolution from 9 km down to 1.8 km. The models were calibrated and validated against ARGO float profiles in the area. The study revealed the mesoscale and sub

  17. DECREASING OF WATER TROPHY IN CASCADE SYSTEMS, ON EXAMPLE OF THE SOŁA RIVER DAM CASCADE (SOUTHERN POLAND

    Directory of Open Access Journals (Sweden)

    Ewa Jachniak

    2014-10-01

    Full Text Available In this thesis the subject of water self-purification in cascade systems of water reservoirs was engaged. The results of hydrobiological research of three dam reservoirs (Tresna, Porąbka and Czaniec, creating the Soła river dam cascade were presented. The trophic status of these reservoirs was defined on the grounds of the concentration of chlorophyll a, biomass of phytoplankton and occurrence of indicating species of planktonic algae. The results of research indicated on decreasing of water trophy in the layout from the highest into the lowest reservoir of the cascade. The average concentrations of chlorophyll a amounted appropriately 19,99 μg·dm-3, 8,74 μg·dm-3 and 4,29 μg·dm-3, instead the average biomass of phytoplankton amounted appropriately 4,1 mg·dm-3, 3,4 mg·dm-3 and 0,1 mg·dm-3. The observed species of algae confirmed occurrence of differences between reservoirs. In Tresna reservoir more species of phytoplankton indicating for eutrophy were thrived, instead in Porąbka and Czaniec reservoirs the species occurring in oligomesotrophic water thrived. Water self-purification in the Soła river dam cascade expressed decreasing of their fertility is important for water management of the region, because the Czaniec reservoir fulfill a function of water-supply reservoir.

  18. Cascades for hydrogen isotope separation using metal hydrides

    International Nuclear Information System (INIS)

    Hill, F.B.; Grzetic, V.

    1982-01-01

    Designs are presented for continuous countercurrent hydrogen isotope separation cascades based on the use of metal hydrides. The cascades are made up of pressure swing adsorption (PSA) or temperature swing adsorption (TSA) stages. The designs were evolved from consideration of previously conducted studies of the separation performance of four types of PSA and TSA processes

  19. Cascades for hydrogen isotope separation using metal hydrides

    Energy Technology Data Exchange (ETDEWEB)

    Hill, F B; Grzetic, V [Brookhaven National Lab., Upton, NY (USA)

    1983-02-01

    Designs are presented for continuous countercurrent hydrogen isotope separation cascades based on the use of metal hydrides. The cascades are made up of pressure swing adsorption (PSA) or temperature swing adsorption (TSA) stages. The designs were evolved from consideration of previously conducted studies of the separation performance of four types of PSA and TSA processes.

  20. A cascaded online uninterruptible power supply using reduced semiconductor

    DEFF Research Database (Denmark)

    Zhang, Lei; Loh, Poh Chiang; Gao, Feng

    2011-01-01

    A cascaded online uninterruptible power supply (UPS) is proposed here that uses 25% lesser semiconductor, as compared to its traditional H-bridge cascaded precedence. Unlike other component-saving configurations where compromises are unavoidable, almost no performance degradations and constraints...

  1. Landscape variation influences trophic cascades in dengue vector food webs.

    Science.gov (United States)

    Weterings, Robbie; Umponstira, Chanin; Buckley, Hannah L

    2018-02-01

    The epidemiology of vector-borne diseases is governed by a structured array of correlative and causative factors, including landscape (for example, rural versus urban), abiotic (for example, weather), and biotic (for example, food web) factors. Studies of mosquito-borne diseases rarely address these multiple factors at large spatial scales, which limits insights into how human alterations of landscapes and food webs alter mosquito abundance. We used structural equation modeling to identify the relative magnitude and direction of landscape, abiotic, and food web factors on Aedes larvae and adults across 70 sites in northern Thailand. Food web factors were modeled as mosquito-predator trophic cascades. Landscape context affected mosquito-predator communities in aquatic and terrestrial environments via cascading food web interactions. Several mosquito predators within these food webs showed potential as biocontrol agents in mosquito population control, but their potentials for control were landscape-dependent. In terrestrial food webs, the habitat-sensitive tokay gecko structured mosquito-predator communities, indicating that a conservation approach to vector control could be a useful addition to existing control efforts.

  2. Major consequences of an intense dense shelf water cascading event on deep-sea benthic trophic conditions and meiofaunal biodiversity

    Directory of Open Access Journals (Sweden)

    A. Pusceddu

    2013-04-01

    Full Text Available Numerous submarine canyons around the world are preferential conduits for episodic dense shelf water cascading (DSWC, which quickly modifies physical and chemical ambient conditions while transporting large amounts of material towards the base of slope and basin. Observations conducted during the last 20 yr in the Lacaze-Duthiers and Cap de Creus canyons (Gulf of Lion, NW Mediterranean Sea report several intense DSWC events. The effects of DSWC on deep-sea ecosystems are almost unknown. To investigate the effects of these episodic events, we analysed changes in the meiofaunal biodiversity inside and outside the canyon. Sediment samples were collected at depths varying from ca. 1000 to > 2100 m in May 2004 (before a major event, April 2005 (during a major cascading event and in October 2005, August 2006, April 2008 and April 2009 (after a major event. We report here that the late winter–early spring 2005 cascading led to a reduction of the organic matter contents in canyon floor sediments down to 1800 m depth, whereas surface sediments at about 2200 m depth showed an increase. Our findings suggest that the nutritional material removed from the shallower continental shelf, canyon floor and flanks, and also the adjacent open slope was rapidly transported to the deep margin. During the cascading event the meiofaunal abundance and biodiversity in the studied deep-sea sediments were significantly lower than after the event. Benthic assemblages during the cascading were significantly different from those in all other sampling periods in both the canyon and deep margin. After only six months from the cessation of the cascading, benthic assemblages in the impacted sediments were again similar to those observed in other sampling periods, thus illustrating a quick recovery. Since the present climate change is expected to increase the intensity and frequency of these episodic events, we anticipate that they will increasingly affect benthic bathyal

  3. Intermittent Flow Regimes in a Transonic Fan Airfoil Cascade

    Directory of Open Access Journals (Sweden)

    J. Lepicovsky

    2004-01-01

    velocity.To date, this flow behavior has only been observed in a linear transonic cascade. Further research is necessary to confirm this phenomenon occurs in actual transonic fans and is not the by-product of an endwall restricted linear cascade.

  4. High-Throughput Screening of Small Molecules Identifies Hepcidin Antagonists

    Science.gov (United States)

    Fung, Eileen; Sugianto, Priscilla; Hsu, Jason; Damoiseaux, Robert; Ganz, Tomas

    2013-01-01

    Anemia of inflammation (AI) is common in patients with infection, autoimmune diseases, cancer, and chronic kidney disease. Unless the underlying condition can be reversed, treatment options are limited to erythropoiesis-stimulating agents with or without intravenous iron therapy, modalities that are not always effective and can cause serious adverse effects. Hepcidin, the iron regulatory hormone, has been identified as a pathogenic factor in the development of AI. To explore new therapeutic options for AI and other iron-related disorders caused by hepcidin excess, we developed a cell-based screen to identify hepcidin antagonists. Of the 70,000 small molecules in the library, we identified 14 compounds that antagonized the hepcidin effect on ferroportin. One of these was fursultiamine, a Food and Drug Administration (FDA)–approved thiamine derivative. Fursultiamine directly interfered with hepcidin binding to its receptor, ferroportin, by blocking ferroportin C326 thiol residue essential for hepcidin binding. Consequently, fursultiamine prevented hepcidin-induced ferroportin ubiquitination, endocytosis, and degradation in vitro and allowed continuous cellular iron export despite the presence of hepcidin, with IC50 in the submicromolar range. Thiamine, the fursultiamine metabolite, and benfotiamine, another thiamine derivative, did not interfere with the effect of hepcidin on ferroportin. Other FDA-approved thiol-reactive compounds were at least 1000-fold less potent than fursultiamine in antagonizing hepcidin. In vivo, fursultiamine did not reproducibly antagonize the effect of hepcidin on serum iron, likely because of its rapid conversion to inactive metabolites. Fursultiamine is a unique antagonist of hepcidin in vitro that could serve as a template for the development of drug candidates that inhibit the hepcidin-ferroportin interaction. PMID:23292796

  5. Collision cascades in HTSC [high temperature superconductors] as possible pinning centres

    International Nuclear Information System (INIS)

    Kirsanov, V.V.; Musin, N.N.; Roskin, D.G.; Shamarina, E.I.

    1993-01-01

    Computer simulation was used to study the development of collision cascades in monocrystals of YBa 2 Cu 3 O 7 , YBa 2 Cu 3 O 6.5 and YBa 2 Cu 3 O 6 which were produced by primary knock-on atoms (PKAs) during fast particle irradiation. Oxygen deficit was found to have an effect on the development of cascades in these phases, with a lowering of oxygen deficit decreasing cascade sizes. The type of PKA was observed to influence the geometry of a cascade. When heavy PKAs form a cascade, the oxygen sublattice is practically undisturbed, with very little disorder; while with oxygen ions as the PKA, the main displacements fall within the oxygen subsystem. In addition, the angular dependences of the displacement threshold energy for yttrium and barium ions are given. (Author)

  6. The Global Outlook for Small Reactors: Opportunities, Challenges and Implementation

    International Nuclear Information System (INIS)

    Hughes, A.

    2012-01-01

    The fascinating topic of small nuclear is becoming more prevalent on the nuclear agenda. The discussions are generally focused within the country of technical origin. In this presentation 'The global outlook for small reactors' Rolls-Royce along with energy business analysts Douglas-Westwood present their shared views on the global opportunities for Small Reactor deployment in the context of the wider energy market. The presentation will: provide a compressive overview of trends and dynamics relating to Small Reactors in the context of the current world energy market, identify specific Small Reactor opportunities and areas of interest, address the challenges and potential solutions for Small Reactor deployment and operation.(author).

  7. Time and temperature dependence of cascade induced defect production in in situ experiments and computer simulation

    International Nuclear Information System (INIS)

    Ishino, Shiori

    1993-01-01

    Understanding of the defect production and annihilation processes in a cascade is important in modelling of radiation damage for establishing irradiation correlation. In situ observation of heavy ion radiation damage has a great prospect in this respect. Time and temperature dependence of formation and annihilation of vacancy clusters in a cascade with a time resolution of 30 ms has been studied with a facility which comprises a heavy ion accelerator and an electron microscope. Formation and annihilation rates of defect clusters have been separately measured by this technique. The observed processes have been analysed by simple kinetic equations, taking into account the sink effect of surface and the defect clusters themselves together with the annihilation process due to thermal emission of vacancies from the defect clusters. Another tool to study time and temperature dependence of defect production in a cascade is computer simulation. Recent results of molecular dynamics calculations on the temperature dependence of cascade evolution are presented, including directional and temperature dependence of the lengths of replacement collision sequences, temperature dependence of the process to reach thermal equilibrium and so on. These results are discussed under general time frame of radiation damage evolution covering from 10 -15 to 10 9 s, and several important issues for the general understanding have been identified. (orig.)

  8. Interband cascade light emitting devices based on type-II quantum wells

    International Nuclear Information System (INIS)

    Yang, Rui Q.; Lin, C.H.; Murry, S.J.

    1997-01-01

    The authors discuss physical processes in the newly developed type-II interband cascade light emitting devices, and review their recent progress in the demonstration of the first type-II interband cascade lasers and the observation of interband cascade electroluminescence up to room temperature in a broad mid-infrared wavelength region (extended to 9 μm)

  9. Dynamics of homogeneous shear turbulence: A key role of the nonlinear transverse cascade in the bypass concept.

    Science.gov (United States)

    Mamatsashvili, G; Khujadze, G; Chagelishvili, G; Dong, S; Jiménez, J; Foysi, H

    2016-08-01

    To understand the mechanism of the self-sustenance of subcritical turbulence in spectrally stable (constant) shear flows, we performed direct numerical simulations of homogeneous shear turbulence for different aspect ratios of the flow domain with subsequent analysis of the dynamical processes in spectral or Fourier space. There are no exponentially growing modes in such flows and the turbulence is energetically supported only by the linear growth of Fourier harmonics of perturbations due to the shear flow non-normality. This non-normality-induced growth, also known as nonmodal growth, is anisotropic in spectral space, which, in turn, leads to anisotropy of nonlinear processes in this space. As a result, a transverse (angular) redistribution of harmonics in Fourier space is the main nonlinear process in these flows, rather than direct or inverse cascades. We refer to this type of nonlinear redistribution as the nonlinear transverse cascade. It is demonstrated that the turbulence is sustained by a subtle interplay between the linear nonmodal growth and the nonlinear transverse cascade. This course of events reliably exemplifies a well-known bypass scenario of subcritical turbulence in spectrally stable shear flows. These two basic processes mainly operate at large length scales, comparable to the domain size. Therefore, this central, small wave number area of Fourier space is crucial in the self-sustenance; we defined its size and labeled it as the vital area of turbulence. Outside the vital area, the nonmodal growth and the transverse cascade are of secondary importance: Fourier harmonics are transferred to dissipative scales by the nonlinear direct cascade. Although the cascades and the self-sustaining process of turbulence are qualitatively the same at different aspect ratios, the number of harmonics actively participating in this process (i.e., the harmonics whose energies grow more than 10% of the maximum spectral energy at least once during evolution) varies

  10. Dynamics of homogeneous shear turbulence: A key role of the nonlinear transverse cascade in the bypass concept

    Science.gov (United States)

    Mamatsashvili, G.; Khujadze, G.; Chagelishvili, G.; Dong, S.; Jiménez, J.; Foysi, H.

    2016-08-01

    To understand the mechanism of the self-sustenance of subcritical turbulence in spectrally stable (constant) shear flows, we performed direct numerical simulations of homogeneous shear turbulence for different aspect ratios of the flow domain with subsequent analysis of the dynamical processes in spectral or Fourier space. There are no exponentially growing modes in such flows and the turbulence is energetically supported only by the linear growth of Fourier harmonics of perturbations due to the shear flow non-normality. This non-normality-induced growth, also known as nonmodal growth, is anisotropic in spectral space, which, in turn, leads to anisotropy of nonlinear processes in this space. As a result, a transverse (angular) redistribution of harmonics in Fourier space is the main nonlinear process in these flows, rather than direct or inverse cascades. We refer to this type of nonlinear redistribution as the nonlinear transverse cascade. It is demonstrated that the turbulence is sustained by a subtle interplay between the linear nonmodal growth and the nonlinear transverse cascade. This course of events reliably exemplifies a well-known bypass scenario of subcritical turbulence in spectrally stable shear flows. These two basic processes mainly operate at large length scales, comparable to the domain size. Therefore, this central, small wave number area of Fourier space is crucial in the self-sustenance; we defined its size and labeled it as the vital area of turbulence. Outside the vital area, the nonmodal growth and the transverse cascade are of secondary importance: Fourier harmonics are transferred to dissipative scales by the nonlinear direct cascade. Although the cascades and the self-sustaining process of turbulence are qualitatively the same at different aspect ratios, the number of harmonics actively participating in this process (i.e., the harmonics whose energies grow more than 10% of the maximum spectral energy at least once during evolution) varies

  11. Cascade Processes in Muonic Hydrogen Atoms

    International Nuclear Information System (INIS)

    Faifman, M. P.; Men'Shikov, L. I.

    2001-01-01

    The QCMC scheme created earlier for cascade calculations in heavy hadronic atoms of hydrogen isotopes has been modified and applied to the study of cascade processes in the μp muonic hydrogen atoms. The distribution of μp atoms over kinetic energies has been obtained and the yields of K-series X-rays per one stopped muon have been calculated.Comparison with experimental data indicated directly that for muonic and pionic atoms new types of non-radiative transitions are essential, while they are negligible for heavy (kaonic, antiprotonic, etc.) atoms. These processes have been considered and their probabilities have been estimated.

  12. Considerations on safeguards approach for small centrifuge enrichment facilities

    International Nuclear Information System (INIS)

    Vicens, Hugo E.; Marzo, Marco A.; Nunes, Vitorio E.

    2004-01-01

    The safeguards' objectives for enrichment facilities encompass the detection of the diversion of declared nuclear material and of facility misuse. The safeguard's approach presently applied for commercial centrifuge enrichment facilities is based on the Hexa partite Project and seems not to be directly applicable to cases of small plants. Since ABACC started its operation one of the main problems faced was the application of safeguards to small centrifuge enrichment plants for testing centrifuges in cascade mode or for small LEU production. These plants consist of a few fully independent cascades, does not operate in a routine basis and panels prevent visual access to the centrifuges and their surroundings for preserving sensitive information. For such plants misuse scenarios seems to dominate, particularly those associated with feeding the plant with undeclared LEU. This paper presents a concise analysis of misuse strategies in small centrifuge facility and alternative safeguard's approach, describing the main control elements to be applied. The particularities arising from the existence of panels or boxes covering the centrifuges are specifically addressed. Two alternatives approaches based on the application of a transitory perimeter control to increase the effectiveness of unannounced inspection and on the application of permanent perimeter control are presented. (author)

  13. Numerical routine for magnetic heat pump cascading

    DEFF Research Database (Denmark)

    Filonenko, Konstantin; Lei, Tian; Engelbrecht, Kurt

    Heat pumps use low-temperature heat absorbed from the energy source to create temperature gradient (TG) across the energy sink. Magnetic heat pumps (MHP) can perform this function through operating active magnetic regeneration (AMR) cycle. For building heating, TGs of up to a few K might...... and 3 K. Changing the number of MHPs, we optimized input parameters to achieve maximum heating powers. We have found that both maximum heating power and COP decrease together with number of heat pumps, but the TGs and the temperature span can be largely increased. References [1] M. Tahavori et al., “A...... be necessary, which is hardly achievable with a single MHP and such techniques as cascading are required. Series and parallel cascading increase the AMR span and heating power, respectively, but do not change TG. Therefore, the intermediate type of cascading was proposed with individual MHPs separately...

  14. Cascade enzymatic reactions for efficient carbon sequestration.

    Science.gov (United States)

    Xia, Shunxiang; Zhao, Xueyan; Frigo-Vaz, Benjamin; Zheng, Wenyun; Kim, Jungbae; Wang, Ping

    2015-04-01

    Thermochemical processes developed for carbon capture and storage (CCS) offer high carbon capture capacities, but are generally hampered by low energy efficiency. Reversible cascade enzyme reactions are examined in this work for energy-efficient carbon sequestration. By integrating the reactions of two key enzymes of RTCA cycle, isocitrate dehydrogenase and aconitase, we demonstrate that intensified carbon capture can be realized through such cascade enzymatic reactions. Experiments show that enhanced thermodynamic driving force for carbon conversion can be attained via pH control under ambient conditions, and that the cascade reactions have the potential to capture 0.5 mol carbon at pH 6 for each mole of substrate applied. Overall it manifests that the carbon capture capacity of biocatalytic reactions, in addition to be energy efficient, can also be ultimately intensified to approach those realized with chemical absorbents such as MEA. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Assessing Socioeconomic Impacts of Cascading Infrastructure Disruptions in a Dynamic Human-Infrastructure Network

    Science.gov (United States)

    2016-07-01

    community behavior as part of a game-theoretical model , and (c) evaluates the cascading propagation of disruptions (due to interdependencies) and... businesses . The conceptual model represents this by placing a generator at each of 137 commercial locations identified by the UTP across the city, each...layered network model , addressing mechanisms of community behavior, mechanisms of disruption propagation, representations of system equilib- rium, and

  16. Holocene volcanism of the upper McKenzie River catchment, central Oregon Cascades, USA

    Science.gov (United States)

    Deligne, Natalia I.; Conrey, Richard M.; Cashman, Katharine V.; Champion, Duane E.; Amidon, William H.

    2016-01-01

    To assess the complexity of eruptive activity within mafic volcanic fields, we present a detailed geologic investigation of Holocene volcanism in the upper McKenzie River catchment in the central Oregon Cascades, United States. We focus on the Sand Mountain volcanic field, which covers 76 km2 and consists of 23 vents, associated tephra deposits, and lava fields. We find that the Sand Mountain volcanic field was active for a few decades around 3 ka and involved at least 13 eruptive units. Despite the small total volume erupted (∼1 km3 dense rock equivalent [DRE]), Sand Mountain volcanic field lava geochemistry indicates that erupted magmas were derived from at least two, and likely three, different magma sources. Single units erupted from one or more vents, and field data provide evidence of both vent migration and reoccupation. Overall, our study shows that mafic volcanism was clustered in space and time, involved both explosive and effusive behavior, and tapped several magma sources. These observations provide important insights on possible future hazards from mafic volcanism in the central Oregon Cascades.

  17. CASCADE - Chemicals as contaminants in the food chain. A network of excellence for research, risk assessment, and education

    Energy Technology Data Exchange (ETDEWEB)

    Oeberg, M.; Haakansson, H. [Karolinska Institutet, Insitute of Environmental Medicine, Stockholm (Sweden); Pongratz, I.; Gustavsson, J.Aa. [Karolinska Institutet, Dept. of Biosciences, Huddinge (Sweden)

    2004-09-15

    Harmful effects of chemical contaminants in food are of major health concern in Europe today. Lack of integration between basic research, risk assessment, and education severely hampers the efforts to reach European excellence in this area. The research activities that are carried out are small in scale and are not well integrated into a coherent structure. To tackle the fragmentation problems and to achieve synergistic effects and full European research potential, the European Commission has initiated a Network of Excellence called CASCADE or ''Chemicals as contaminants in the food chain: a network of excellence for research, risk assessment, and education'' The contract is running for five years and is worth over 14 million with partners from eighteen research centres. The network has the potential and goal to be a world force in knowledge on health issues related to chemical contaminants in food. Focus is on chemical residues that act via and/or interfere with cell regulation at the level of nuclear receptors. The risk assessment integration parts of the network aim to increase the awareness among scientists and others of the need to bring multiple aspects of scientific information into use in risk assessment.

  18. Improved efficiency in organic/inorganic hybrid solar cells by interfacial modification of ZnO nanowires with small molecules

    International Nuclear Information System (INIS)

    Chang, Sehoon; Park, Hyesung; Cheng, Jayce J; Rekemeyer, Paul H; Gradečak, Silvija

    2014-01-01

    We demonstrate improved photovoltaic performance of ZnO nanowire/poly(3-hexylthiophene) (P3HT) nanofiber hybrid devices using an interfacial modification of ZnO nanowires. Formation of cascade energy levels between the ZnO nanowire and P3HT nanofiber was achieved by interfacial modification of ZnO nanowires using small molecules tetraphenyldibenzoperiflanthene (DBP) and 3,4,9,10-perylenetetracarboxylic bisbenzimidazole (PTCBI). The successful demonstration of improved device performance owing to the cascade energy levels by small molecule modification is a promising approach toward highly efficient organic/inorganic hybrid solar cells. (paper)

  19. Self-organized Criticality and Synchronization in a Pulse-coupled Integrate-and-Fire Neuron Model Based on Small World Networks

    International Nuclear Information System (INIS)

    Lin Min; Chen Tianlun

    2005-01-01

    A lattice model for a set of pulse-coupled integrate-and-fire neurons with small world structure is introduced. We find that our model displays the power-law behavior accompanied with the large-scale synchronized activities among the units. And the different connectivity topologies lead to different behaviors in models of integrate-and-fire neurons.

  20. Hybrid Modulation Scheme for Cascaded H-Bridge Inverter Cells ...

    African Journals Online (AJOL)

    This work proposes a switching technique for cascaded H-Bridge (CHB) cells. Single carrier Sinusoidal PWM (SCSPWM) scheme is employed in the generation of the gating signals. A sequential switching and base PWM circulation schemes are presented for this fundamental cascaded multilevel inverter topology.

  1. Cascade in muonic and pionic atoms with Z = 1

    International Nuclear Information System (INIS)

    Markushin, V.E.

    1999-01-01

    Recent theoretical and experimental studies of the exotic atoms with Z = 1 are reviewed. An interplay between the atomic internal and external degrees of freedom is essential for a good description of the atomic cascade. The perspective of ab initio cascade calculations is outlined

  2. Climate Change and Baleen Whale Trophic Cascades in Greenland

    Science.gov (United States)

    2009-09-30

    DISTRIBUTION STATEMENT A: Approved for public release; distribution is unlimited. Climate Change and Baleen Whale Trophic Cascades in Greenland...SUBTITLE Climate Change And Baleen Whale Trophic Cascades In Greenland 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S

  3. A multivariate approach to heavy flavour tagging with cascade training

    International Nuclear Information System (INIS)

    Bastos, J; Liu, Y

    2007-01-01

    This paper compares the performance of artificial neural networks and boosted decision trees, with and without cascade training, for tagging b-jets in a collider experiment. It is shown, using a Monte Carlo simulation of WH→lνq q-bar events, that for a b-tagging efficiency of 50%, the light jet rejection power given by boosted decision trees without cascade training is about 55% higher than that given by artificial neural networks. The cascade training technique can improve the performance of boosted decision trees and artificial neural networks at this b-tagging efficiency level by about 35% and 80% respectively. We conclude that the cascade trained boosted decision trees method is the most promising technique for tagging heavy flavours at collider experiments

  4. Study on computer-aided simulation procedure for multicomponent separating cascade

    International Nuclear Information System (INIS)

    Kinoshita, Masahiro

    1982-11-01

    The present report reviews the author's study on the computer-aided simulation procedure for a multicomponent separating cascade. As a conclusion, two very powerful simulation procedures have been developed for cascades composed of separating elements whose separation factors are very large. They are applicable in cases where interstage flow rates are input variables for the calculation and stage separation factors are given either as constants or as functions of compositions of the up and down streams. As an application of the new procedure, a computer-aided simulation study has been performed for hydrogen isotope separating cascades by porous membrane method. A cascade system configuration is developed and pertinent design specifications are determined in an example case of the feed conditions and separation requirements. (author)

  5. World Gastroenterology Organization Practice Guidelines for the diagnosis and management of IBD in 2010

    DEFF Research Database (Denmark)

    Bernstein, Charles N; Fried, Michael; Krabshuis, J H

    2010-01-01

    have, in the past, been most evident in the developed world, their prevalence in the developing world has been gradually increasing in recent decades. This poses unique issues in diagnosis and management which have been scarcely addressed in the literature or in extant guidelines. Depending...... on the nature of the complaints, investigations to diagnose either form of IBD or to assess disease activity will vary and will also be influenced by geographic variations in other conditions that might mimic IBD. Similarly, therapy varies depending on the phenotype of the disease being treated and available...... resources. The World Gastroenterology Organization has, accordingly, developed guidelines for diagnosing and treating IBD using a cascade approach to account for variability in resources in countries around the world....

  6. Substrate-driven chemotactic assembly in an enzyme cascade

    Science.gov (United States)

    Zhao, Xi; Palacci, Henri; Yadav, Vinita; Spiering, Michelle M.; Gilson, Michael K.; Butler, Peter J.; Hess, Henry; Benkovic, Stephen J.; Sen, Ayusman

    2018-03-01

    Enzymatic catalysis is essential to cell survival. In many instances, enzymes that participate in reaction cascades have been shown to assemble into metabolons in response to the presence of the substrate for the first enzyme. However, what triggers metabolon formation has remained an open question. Through a combination of theory and experiments, we show that enzymes in a cascade can assemble via chemotaxis. We apply microfluidic and fluorescent spectroscopy techniques to study the coordinated movement of the first four enzymes of the glycolysis cascade: hexokinase, phosphoglucose isomerase, phosphofructokinase and aldolase. We show that each enzyme independently follows its own specific substrate gradient, which in turn is produced by the preceding enzymatic reaction. Furthermore, we find that the chemotactic assembly of enzymes occurs even under cytosolic crowding conditions.

  7. Signaling Cascades: Consequences of Varying Substrate and Phosphatase Levels

    DEFF Research Database (Denmark)

    Feliu, Elisenda; Knudsen, Michael; Wiuf, Carsten Henrik

    2012-01-01

    We study signaling cascades with an arbitrary number of layers of one-site phosphorylation cycles. Such cascades are abundant in nature and integrated parts of many pathways. Based on the Michaelis-Menten model of enzyme kinetics and the law of mass-action, we derive explicit analytic expressions...

  8. High energy evolution of soft gluon cascades

    International Nuclear Information System (INIS)

    Shuvaev, A.; Wallon, S.

    2006-01-01

    In this paper we derive an evolution equation for the gluon density in soft gluon cascades emitted from any colored source, in the leading logarithmic approximation of perturbative QCD. We show that this equation has the same form as the BFKL equation in the forward case. An explicit expression for the total cascade wavefunction involving an arbitrary number of soft gluons is obtained. Renormalization of the colored source wavefunction turns out to be responsible for the reggeization of the source. (orig.)

  9. High energy evolution of soft gluon cascades

    Energy Technology Data Exchange (ETDEWEB)

    Shuvaev, A. [St. Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg district (Russian Federation); Wallon, S. [Universite Paris XI, Laboratoire de Physique Theorique, Orsay Cedex (France)

    2006-04-15

    In this paper we derive an evolution equation for the gluon density in soft gluon cascades emitted from any colored source, in the leading logarithmic approximation of perturbative QCD. We show that this equation has the same form as the BFKL equation in the forward case. An explicit expression for the total cascade wavefunction involving an arbitrary number of soft gluons is obtained. Renormalization of the colored source wavefunction turns out to be responsible for the reggeization of the source. (orig.)

  10. Techno-economic assessment for the integration into a multi-product plant based on cascade utilization of geothermal energy

    International Nuclear Information System (INIS)

    Rubio-Maya, Carlos; Pastor Martínez, Edgar; Romero, Carlos E.; Ambriz Díaz, Víctor M.; Pacheco-Ibarra, J. Jesús

    2016-01-01

    Highlights: • Cascade utilization of low- and mid-temperature geothermal energy is presented. • The system consists of three thermal levels producing power, ice and useful heat. • A techno-economic analysis is performed evaluating energy and economic benefits. • A simple optimization algorithm was developed to optimize system benefits. • Inconvenience of low thermal efficiency and high capital cost of ORC were overcome. - Abstract: The Organic Rankine Cycle (ORC) is a technology that has reached maturity in cogeneration or waste heat applications. However, due to low thermal efficiency and high capital cost of ORC machines, geothermal-based ORC applications represent only a small percent sharing of the geothermal power capacity worldwide. Several countries have reported a great potential of low- and mid-temperature geothermal energy, representing an opportunity to explore a more efficient ORC integration into non-conventional applications of geothermal energy. One alternative, resembling the polygeneration concept, is known as cascade utilization of geothermal energy, where different energy outputs or products can be obtained at the same time, while improving thermal and economic performance. In this paper, a techno-economic analysis for the selection of small capacity ORC machines and absorption chillers (for ice production), to be integrated into a polygeneration plant that makes use of geothermal energy in a cascade arrangement, is presented. A simple cascade system that consists of three sequential thermal levels, producing simultaneously power, ice and useful heat is proposed, considering typical temperatures of geothermal zones in Mexico. A simple optimization algorithm, based on energy and economic models, including binary variables and manufacturer’s data, was developed to evaluate and determine optimal ORC and absorption chiller units. Results show, firstly, that inconvenience of low thermal efficiency and high capital cost of ORC machines can

  11. Modeling techniques for quantum cascade lasers

    Energy Technology Data Exchange (ETDEWEB)

    Jirauschek, Christian [Institute for Nanoelectronics, Technische Universität München, D-80333 Munich (Germany); Kubis, Tillmann [Network for Computational Nanotechnology, Purdue University, 207 S Martin Jischke Drive, West Lafayette, Indiana 47907 (United States)

    2014-03-15

    Quantum cascade lasers are unipolar semiconductor lasers covering a wide range of the infrared and terahertz spectrum. Lasing action is achieved by using optical intersubband transitions between quantized states in specifically designed multiple-quantum-well heterostructures. A systematic improvement of quantum cascade lasers with respect to operating temperature, efficiency, and spectral range requires detailed modeling of the underlying physical processes in these structures. Moreover, the quantum cascade laser constitutes a versatile model device for the development and improvement of simulation techniques in nano- and optoelectronics. This review provides a comprehensive survey and discussion of the modeling techniques used for the simulation of quantum cascade lasers. The main focus is on the modeling of carrier transport in the nanostructured gain medium, while the simulation of the optical cavity is covered at a more basic level. Specifically, the transfer matrix and finite difference methods for solving the one-dimensional Schrödinger equation and Schrödinger-Poisson system are discussed, providing the quantized states in the multiple-quantum-well active region. The modeling of the optical cavity is covered with a focus on basic waveguide resonator structures. Furthermore, various carrier transport simulation methods are discussed, ranging from basic empirical approaches to advanced self-consistent techniques. The methods include empirical rate equation and related Maxwell-Bloch equation approaches, self-consistent rate equation and ensemble Monte Carlo methods, as well as quantum transport approaches, in particular the density matrix and non-equilibrium Green's function formalism. The derived scattering rates and self-energies are generally valid for n-type devices based on one-dimensional quantum confinement, such as quantum well structures.

  12. Modeling techniques for quantum cascade lasers

    Science.gov (United States)

    Jirauschek, Christian; Kubis, Tillmann

    2014-03-01

    Quantum cascade lasers are unipolar semiconductor lasers covering a wide range of the infrared and terahertz spectrum. Lasing action is achieved by using optical intersubband transitions between quantized states in specifically designed multiple-quantum-well heterostructures. A systematic improvement of quantum cascade lasers with respect to operating temperature, efficiency, and spectral range requires detailed modeling of the underlying physical processes in these structures. Moreover, the quantum cascade laser constitutes a versatile model device for the development and improvement of simulation techniques in nano- and optoelectronics. This review provides a comprehensive survey and discussion of the modeling techniques used for the simulation of quantum cascade lasers. The main focus is on the modeling of carrier transport in the nanostructured gain medium, while the simulation of the optical cavity is covered at a more basic level. Specifically, the transfer matrix and finite difference methods for solving the one-dimensional Schrödinger equation and Schrödinger-Poisson system are discussed, providing the quantized states in the multiple-quantum-well active region. The modeling of the optical cavity is covered with a focus on basic waveguide resonator structures. Furthermore, various carrier transport simulation methods are discussed, ranging from basic empirical approaches to advanced self-consistent techniques. The methods include empirical rate equation and related Maxwell-Bloch equation approaches, self-consistent rate equation and ensemble Monte Carlo methods, as well as quantum transport approaches, in particular the density matrix and non-equilibrium Green's function formalism. The derived scattering rates and self-energies are generally valid for n-type devices based on one-dimensional quantum confinement, such as quantum well structures.

  13. Bearing-Only Formation Control for Cascade Multirobots

    Directory of Open Access Journals (Sweden)

    Qing Han

    2016-01-01

    Full Text Available A new formation control method is proposed, which is used to queue multirobots in a single-direction cascade structure. In the cascade formation, each robot is a follower for the previous robot and a leader for the next robot, and the robots in the middle act as both leader and follower. The follower robot can only observe the bearing information of the leader robot. The observability of the cascade leader-follower formation is studied, which shows that the bearing-only observation meets the observability conditions required for the nonlinear system. Based on the bearing-only observations, the unscented Kalman filter (UKF is employed for the state estimation of the leader and the follower robots at all levels, which enables the real-time movement control of the follower robots via the input-output feedback control. Simulation results demonstrate that the proposed approach can efficiently control the formation of multirobots as desired.

  14. Cascade laser applications: trends and challenges

    Science.gov (United States)

    d'Humières, B.; Margoto, Éric; Fazilleau, Yves

    2016-03-01

    When analyses need rapid measurements, cost effective monitoring and miniaturization, tunable semiconductor lasers can be very good sources. Indeed, applications like on-field environmental gas analysis or in-line industrial process control are becoming available thanks to the advantage of tunable semiconductor lasers. Advances in cascade lasers (CL) are revolutionizing Mid-IR spectroscopy with two alternatives: interband cascade lasers (ICL) in the 3-6μm spectrum and quantum cascade lasers (QCL), with more power from 3 to 300μm. The market is getting mature with strong players for driving applications like industry, environment, life science or transports. CL are not the only Mid-IR laser source. In fact, a strong competition is now taking place with other technologies like: OPO, VCSEL, Solid State lasers, Gas, SC Infrared or fiber lasers. In other words, CL have to conquer a share of the Mid-IR application market. Our study is a market analysis of CL technologies and their applications. It shows that improvements of components performance, along with the progress of infrared laser spectroscopy will drive the CL market growth. We compare CL technologies with other Mid-IR sources and estimate their share in each application market.

  15. Noise properties and cascadability of SOA-EA regenerators

    DEFF Research Database (Denmark)

    Öhman, Filip; Bischoff, Svend; Tromborg, Bjarne

    2002-01-01

    We suggest and analyse a new device containing concatenated pairs of semiconductor optical amplifiers (SOAs) and electroabsorption modulators (EAs). The device has regenerative properties and improves the cascadability of optical fibre links.......We suggest and analyse a new device containing concatenated pairs of semiconductor optical amplifiers (SOAs) and electroabsorption modulators (EAs). The device has regenerative properties and improves the cascadability of optical fibre links....

  16. Computer codes for simulating atomic-displacement cascades in solids subject to irradiation

    International Nuclear Information System (INIS)

    Asaoka, Takumi; Taji, Yukichi; Tsutsui, Tsuneo; Nakagawa, Masayuki; Nishida, Takahiko

    1979-03-01

    In order to study atomic displacement cascades originating from primary knock-on atoms in solids subject to incident radiation, the simulation code CASCADE/CLUSTER is adapted for use on FACOM/230-75 computer system. In addition, the code is modified so as to plot the defect patterns in crystalline solids. As other simulation code of the cascade process, MARLOWE is also available for use on the FACOM system. To deal with the thermal annealing of point defects produced in the cascade process, the code DAIQUIRI developed originally for body-centered cubic crystals is modified to be applicable also for face-centered cubic lattices. By combining CASCADE/CLUSTER and DAIQUIRI, we then prepared a computer code system CASCSRB to deal with heavy irradiation or saturation damage state of solids at normal temperature. Furthermore, a code system for the simulation of heavy irradiations CASCMARL is available, in which MARLOWE code is substituted for CASCADE in the CASCSRB system. (author)

  17. LIMIT SOLUTIONS OF EQUATIONS OF A DC HIGH-VOLTAGE CASCADE GENERATOR

    Directory of Open Access Journals (Sweden)

    V. O. Brzhezitsky

    2015-04-01

    Full Text Available In the paper the issue of calculating the high voltage cascade mode oscillator with a nonlinear load using the analytical method under different conditions of selection values of its components is presented. The peculiarity of the method of the study is that during multivariate calculations output parameters load generator remain unchanged. For high-voltage cascade direct current power found conditions under which can be significantly reduced high capacity capacitors cascade generator. The calculations show that acceptable for practical applications of high-voltage characteristics of cascade generators can be achieved with substantial reduction of the volume of their constituents, and thus substantial decline in their value.

  18. Interferometric modulation of quantum cascade interactions

    Science.gov (United States)

    Cusumano, Stefano; Mari, Andrea; Giovannetti, Vittorio

    2018-05-01

    We consider many-body quantum systems dissipatively coupled by a cascade network, i.e., a setup in which interactions are mediated by unidirectional environmental modes propagating through a linear optical interferometer. In particular we are interested in the possibility of inducing different effective interactions by properly engineering an external dissipative network of beam splitters and phase shifters. In this work we first derive the general structure of the master equation for a symmetric class of translation-invariant cascade networks. Then we show how, by tuning the parameters of the interferometer, one can exploit interference effects to tailor a large variety of many-body interactions.

  19. In-World Behaviors and Learning in a Virtual World

    Science.gov (United States)

    Nadolny, Larysa; Childs, Mark

    2014-01-01

    Educational virtual worlds can give students opportunities that would not otherwise be possible in face-to-face settings. The SciEthics Interactive simulations allow learners to conduct scientific research and practice ethical decision-making within a virtual world. This study examined the in-world behaviors that identify students who perceive…

  20. Empirical Analysis on Evolution and Small World Effect of Chinese Enterprise-Enterprise Patent Cooperation Network: From the Perspective of Open Innovation

    Directory of Open Access Journals (Sweden)

    Wei Li

    2013-10-01

    Full Text Available The patent cooperation network which enterprises join is a very important network platform for enterprises’ open innovation. However, very limited work has been done to empirically investigate the dynamic change process of the network in China. To address this issue, this paper analyzes dynamic change process of cooperation network of enterprises and the small-world effect of the biggest subgroup according to the data of 36731 items of cooperative patents between enterprises from 1985 to 2010 published by the State Intellectual Property Office of China. A conclusion can be drawn from the analysis results that the biggest subgroup has the characteristics of small-world effect, but the overall network structure also has some defects, which limit the development of open innovation. For the first time, suggestions on open innovation strategies are put forward to provide theoretical reference for both the government and enterprises.