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Sample records for cascade intranuclear gamma

  1. Shell structure and few-nucleon removal in intranuclear cascade

    CERN Document Server

    Mancusi, Davide; Carbonell, Jaume; Cugnon, Joseph; David, Jean-Christophe; Leray, Sylvie

    2014-01-01

    It is well known that intranuclear-cascade models generally overestimate the cross sections for one-proton removal from heavy, stable nuclei by a high-energy proton beam, but they yield reasonable predictions for one-neutron removal from the same nuclei and for one-nucleon removal from light targets. We use simple shell-model calculations to investigate the reasons of this deficiency. We find that a correct description of the neutron skin and of the energy density in the nuclear surface is crucial for the aforementioned observables. Neither ingredient is sufficient if taken separately.

  2. Extension of the Li\\`ege Intranuclear-Cascade model to reactions induced by light nuclei

    CERN Document Server

    Mancusi, Davide; Cugnon, Joseph; David, Jean-Christophe; Kaitaniemi, Pekka; Leray, Sylvie

    2014-01-01

    The purpose of this paper is twofold. First, we present the extension of the Li\\`ege Intranuclear Cascade model to reactions induced by light ions. Second, we describe the C++ version of the code, which it is physics-wise equivalent to the legacy version, is available in Geant4 and will serve as the basis for all future development of the model. We describe the ideas upon which we built our treatment of nucleus-nucleus reactions and we compare the model predictions against a vast set of heterogeneous experimental data. In spite of the discussed limitations of the intranuclear-cascade scheme, we find that our model yields valid predictions for a number of observables and positions itself as one of the most attractive alternatives available to Geant4 users for the simulation of light-ion-induced reactions.

  3. Improving proton-induced one-nucleon removal in intranuclear cascade

    CERN Document Server

    Mancusi, Davide; Carbonell, Jaume; Cugnon, Joseph; David, Jean-Christophe; Leray, Sylvie

    2014-01-01

    It is a well-established fact that intranuclear-cascade models generally fail to consistently reproduce the cross sections for one-proton and one-neutron removal from stable nuclei by a high-energy proton beam. We use simple shell-model calculations to investigate the reasons of this deficiency. We find that a refined description of the neutron skin and of the energy density in the nuclear surface is crucial for the aforementioned observables, and that neither ingredient is sufficient if taken separately. As a by-product, the predictions for removal of several nucleons are also improved by the refined treatment.

  4. Extended Intranuclear Cascade model for pickup reactions induced by 50-MeV-range protons

    Directory of Open Access Journals (Sweden)

    Uozumi Yusuke

    2016-01-01

    Full Text Available The intranuclear cascade model was investigated to explain (p, dx and (p, ax reactions at incident energies of around 50 MeV. Since these reactions are governed mainly by the direct pickup process, the model was expanded to include exclusive pickup processes leading to hole-state-excitations. The energy of the outgoing clusters is determined with single-particle energies of transferred nucleons, the reaction Q-value, and the recoil of the residual nucleus. The rescattering of the produced cluster inside the nucleus is treated within the intranuclear cascade model. The emission angle is given by the sum of momentum vectors of transferred nucleons in addition to the deflection at the nuclear surface, which was introduced to explain angular distributions of elastic scattering. Double differential cross sections of reactions were calculated and compared with experimental data. The proposed model showed a high predictive power over the wide range of emission energies and angles. The treatment ofthe cluster transport inside the nucleus was also verified.

  5. $K^{+}$ momentum spectrum from $(K^{-},K^{+})$ reactions in intranuclear cascade model

    CERN Document Server

    Nara, Y; Harada, T; Engel, A

    1996-01-01

    In a framework of intranuclear cascade (INC) type calculation, we study a momentum spectrum in reactions \\KK at a beam momentum of 1.65 GeV/c. INC model calculations are compared with the relativistic impulse approximation (RIA) calculations to perform the detailed study of the reaction mechanism. We find that the INC model can reproduce the experimental data on various targets. Especially, in the low-momentum region, the forward-angle cross sections of the $(K^-,K^+)$ reaction on from light to heavy targets are consistently explained with the two-step strangeness exchange and production processes with various intermediate mesons, and $\\phi$, $a_0$ and $f_0$ productions and their decay into $K^+K^-$. In the two-step processes, inclusion of meson and hyperon resonances is found to be essential.

  6. Improved Intranuclear Cascade Models for the Codes CEM2k and LAQGSM

    CERN Document Server

    Mashnik, S G; Sierk, A J; Prael, R E

    2005-01-01

    An improved version of the Cascade-Exciton Model (CEM) of nuclear reactions implemented in the codes CEM2k and the Los Alamos version of the Quark-Gluon String Model (LAQGSM) has been developed recently at LANL to describe reactions induced by particles and nuclei at energies up to hundreds of GeV/nucleon for a number of applications. We present several improvements to the intranuclear cascade models used in CEM2k and LAQGSM developed recently to better describe the physics of nuclear reactions. First, we incorporate the photonuclear mode from CEM2k into LAQGSM to allow it to describe photonuclear reactions, not previously modeled there. Then, we develop new approximations to describe more accurately experimental elementary energy and angular distributions of secondary particles from hadron-hadron and photon-hadron interactions using available data and approximations published by other authors. Finally, to consider reactions involving very highly excited nuclei (E* > 2-3 MeV/A), we have incorporated into CEM2...

  7. The performance of a new Geant4 Bertini intra-nuclear cascade model in high throughput computing (HTC) cluster architecture

    Energy Technology Data Exchange (ETDEWEB)

    Aatos, Heikkinen; Andi, Hektor; Veikko, Karimaki; Tomas, Linden [Helsinki Univ., Institute of Physics (Finland)

    2003-07-01

    We study the performance of a new Bertini intra-nuclear cascade model implemented in the general detector simulation tool-kit Geant4 with a High Throughput Computing (HTC) cluster architecture. A 60 node Pentium III open-Mosix cluster is used with the Mosix kernel performing automatic process load-balancing across several CPUs. The Mosix cluster consists of several computer classes equipped with Windows NT workstations that automatically boot, daily and become nodes of the Mosix cluster. The models included in our study are a Bertini intra-nuclear cascade model with excitons, consisting of a pre-equilibrium model, a nucleus explosion model, a fission model and an evaporation model. The speed and accuracy obtained for these models is presented. (authors)

  8. Cross sections of proton- and neutron-induced reactions by the Liège intranuclear cascade model

    Science.gov (United States)

    Chen, Jian; Dong, Tiekuang; Ren, Zhongzhou

    2016-06-01

    The purpose of the paper is mainly to test the validity of the Liège intranuclear cascade (INCL) model in calculating the cross sections of proton-induced reactions for cosmogenic nuclei using the newly compiled database of proton cross sections. The model calculations of 3He display the rising tendency of cross sections with the increase of energy, in accordance with the experimental data. Meanwhile, the differences between the theoretical results and experimental data of production cross sections (10Be and 26Al) are generally within a factor of 3, meaning that the INCL model works quite well for the proton-induced reactions. Based on the good agreement, we predict the production cross sections of 26Al from reactions n + 27Al, n + 28Si, and n + 40Ca and those of 10Be from reactions n + 16O and n + 28Si. The results also show a good agreement with a posteriori excitation functions.

  9. New potentialities of the Li\\`ege intranuclear cascade (INCL) model for reactions induced by nucleons and light charged particles

    CERN Document Server

    Boudard, Alain; David, Jean-Christophe; Leray, Sylvie; Mancusi, Davide

    2012-01-01

    The new version (INCL4.6) of the Li`ege intranuclear cascade (INC) model for the description of spallation reactions is presented in detail. Compared to the standard version (INCL4.2), it incorporates several new features, the most important of which are: (i) the inclusion of cluster production through a dynamical phase space coalescence model, (ii) the Coulomb deflection for entering and outgoing charged particles, (iii) the improvement of the treatment of Pauli blocking and of soft collisions, (iv) the introduction of experimental threshold values for the emission of particles, (v) the improvement of pion dynamics, (vi) a detailed procedure for the treatment of light-cluster induced reactions taking care of the effects of binding energy of the nucleons inside the incident cluster and of the possible fusion reaction at low energy. Performances of the new model concerning nucleon-induced reactions are illustrated. Whenever necessary, the INCL4.6 model is coupled to the ABLA07 deexcitation model and the respec...

  10. An intranuclear cascade-percolation approach for protons and light fragments production in neon-niobium reactions at 400 and 800 MeV per nucleon

    Energy Technology Data Exchange (ETDEWEB)

    Montarou, G.; Marroncle, J.; Alard, J.P.; Augerat, J.; Bastid, N.; Charmensat, P.; Dupieux, P.; Fraysse, L.; Parizet, M.J.; Rahmani, A. [Clermont-Ferrand-2 Univ., 63 - Aubiere (France). Lab. de Physique Corpusculaire; Babinet, R.; Cavata, C.; Demoulins, M.; Fanet, H.; Gosset, J.; L`Hote, D.; Lucas, B.; Poitou, J.; Valette, O. [CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France). Dept. d`Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l`Instrumentation Associee; Lemaire, M.C. [Laboratoire National Saturne, Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France); Brochard, F.; Gorodetzky, P.; Racca, C. [Strasbourg-1 Univ., 67 (France). Centre de Recherches Nucleaires; Cugnon, J. [Liege Univ. (Belgium). Inst. de Physique

    1992-12-31

    The results of intranuclear cascade calculations (ideal gas with two body collisions and no mean-field), complemented by a simple percolation procedure, are compared with experimental data on protons and light nuclear fragments (d, t, {sup 3}He and {sup 4}He) measured in 400 and 800 MeV/nucleon Ne+Nb collisions using the large solid angle detector DIOGENE. The model reproduces quite well global experimental observables like nuclear fragment multiplicity distributions or production cross-sections, and nuclear fragment to proton ratios. For rapidity distributions the best agreement occurs for peripheral reactions. Transverse momentum analysis confirms once again that the cascade, although being a microscopic approach, gives too small a collective flow. For heavier nuclear fragments conclusions are not so clear. Since the cross-sections are the main ingredients of the detailed treatment of the first stage of the reaction by the intranuclear cascade, such an approach can be very fruitful in order to infer informations on effective nucleon-nucleon cross-sections. (authors). 31 refs., 23 figs., 6 tabs.

  11. Intranuclear cascade-percolation approach for protons and light fragments production in neon-niobium reactions at 400 and 800 MeV per nucleon

    Energy Technology Data Exchange (ETDEWEB)

    Montarou, G.; Marroncle, J.; Alard, J.P.; Augerat, J.; Bastid, N.; Charmensat, P.; Dupieux, P.; Fraysse, L.; Parizet, M.J.; Rahmani, A. (Laboratoire de Physique Corpusculaire, Universite Blaise Pascal, IN2P3-CNRS, Clermont-Ferrand, F-63177 Aubiere Cedex (France)); Babinet, R.; Cavata, C.; Demoulins, M.; Fanet, H.; Gosset, J.; L' Hote, D.; Lemaire, M.C.; Lucas, B.; Poitou, J.; Valette, O. (Service de Physique Nucleaire, DAPNIA, CE-Saclay, F-91191 Gif-sur-Yvette Cedex (France)); Brochard, F.; Gorodetzky, P.; Racca, C. (Centre de Recherches Nucleaires, 23 rue du Loess, BP 20 CR, 67037 Strasbourg (France)); Cugnon, J. (Institut de Physique, Universite de Liege, Sart Tilman, B-4000 Liege 1 (Belgium))

    1993-06-01

    The results of intranuclear cascade calculations (ideal gas with two-body collisions and no mean field), complemented by a simple percolation procedure, are compared with experimental data on protons and light nuclear fragments ([ital d], [ital t], [sup 3]He, and [sup 4]He) measured in 400 and 800 MeV/nucleon Ne+Nb collisions using a large solid angle detector. The model reproduces quite well global experimental observables like nuclear fragment multiplicity distributions or production cross sections, and nuclear fragment to proton ratios. For rapidity distributions the best agreement occurs for peripheral reactions. Transverse momentum analysis confirms once again that the cascade, although being a microscopic approach, gives too small a collective flow, the best agreement being reached for [ital Z]=2 nuclear fragments. Nevertheless these comparisons are encouraging for further improvements of the model. Moreover, such an approach is easy to extend to any other models that could calculate the nucleon phase space distribution after the compression stage of the reaction, when light nuclear fragments emitted at large angles are constructed from percolation.

  12. Gamma ray pulsars emission from extended polar cap cascades

    CERN Document Server

    Daugherty, J K; Daugherty, Joseph K; Harding, Alice K

    1995-01-01

    We have used a Monte Carlo simulation of a Polar Cap (PC) model of gamma-ray pulsars to estimate light curves and phase-resolved spectra for sources whose rotational and magnetic axes are oriented so that only one of the magnetic poles produces emission directed at the Earth. In this Single Polar Cap (SPC) scenario, even sources whose light curves have two distinct peaks (Crab, Vela, Geminga, PSR B1951+32) are due to emission concentrated near the rim of a single PC. If the inclination alpha is comparable to the half-width of the PC gamma-beam, alpha ~ theta_{b}, the peak-to-peak phase separation can have the large values (0.4 - 0.5) observed from these sources. In the model presented here we attribute the observed interpeak emission to pair cascades above the PC interior. Our simulation assumes the physics of conventional PC models, in which the gamma rays are due to photon-pair cascades initiated by curvature radiation from the acceleration of electrons above the PCs. In this work we assume that the acceler...

  13. Electromagnetic cascade masquerade: a way to mimic $\\gamma$--ALP mixing effects in blazar spectra

    CERN Document Server

    Dzhatdoev, T A; Kircheva, A P; Lyukshin, A A

    2016-01-01

    Most of the studies on extragalactic {\\gamma}-ray propagation performed up to now only accounted for primary gamma-ray absorption and adiabatic losses (absorption-only model). However, there is growing evidence that this model is oversimplified and must be modified in some way. (...) There are many hints that a secondary component from electromagnetic cascades initiated by primary $\\gamma$-rays or nuclei may be observed in the spectra of some blazars. We study the impact of electromagnetic cascades from primary $\\gamma$-rays or protons on the physical interpretation of blazar spectra obtained with imaging Cherenkov telescopes. We use the publicly-available code ELMAG to compute observable spectra of electromagnetic cascades from primary $\\gamma$-rays. For the case of primary proton, we develop a simple, fast, and reasonably accurate hybrid method to calculate the observable spectrum. (...) Electromagnetic cascades show at least two very distinct regimes labeled by the energy of the primary $\\gamma$-ray ($E_{0...

  14. Gamma Cascade Transition of 51V(n,g)V52 Reaction

    CERN Document Server

    Son, Nguyen An; Hoa, Nguyen Duc; Tan, Vuong Huu; Thang, Ho Huu; Trinh, Dao Manh; Hai, Nguyen Xuan

    2013-01-01

    The thermal neutron capture gamma radiations for 51V(n, g)52V reaction have been studied at Dalat Nuclear Research Reactor (DNRR). The gamma two-step cascade transition was measured by event-event coincidence spectrometer. The added-neutron binding energy in 52V was measured as 7.31 MeV. Energy and intensity transition of cascades were consistent with prediction of single particle model. Further more, the spin and parity of levels were confined.

  15. New possibilities for improving the accuracy of parameter calculations for cascade gamma-ray decay of heavy nuclei

    CERN Document Server

    Sukhovoj, A M; Khitrov, V A

    2001-01-01

    The level density and radiative strength functions which accurately reproduce the experimental intensity of two- step cascades after thermal neutron capture and the total radiative widths of the compound states were applied to calculate the total gamma-ray spectra from the (n,gamma) reaction. In some cases, analysis showed far better agreement with experiment and gave insight into possible ways in which these parameters need to be corrected for further improvement of calculation accuracy for the cascade gamma-decay of heavy nuclei.

  16. Photon Splitting Cascades in $\\gamma$-Ray Pulsars and the Spectrum of PSR1509-58

    CERN Document Server

    Harding, A K; Gonthier, P L; Harding, Alice K.; Baring, Matthew G.; Gonthier, Peter L.

    1996-01-01

    Magnetic photon splitting, a QED process that becomes important only in magnetic fields approaching the quantum critical value, B_cr = 4.41 X 10^13 Gauss, is investigated as a mechanism for attenuation of gamma-rays emitted near the surface of strongly-magnetized pulsars. We model photon splitting attenuation and subsequent splitting cascades in gamma-ray pulsars, including the dipole field and curved spacetime geometry of the neutron star magnetosphere. We focus specifically on PSR1509-58, which has the highest surface magnetic field of all the gamma-ray pulsars (B_0 = 3 X 10^13 Gauss). We find that splitting will not be important for most gamma-ray pulsars, i.e. those with B_0 ~ 0.3 B_cr, where the splitting attenuation lengths and escape energies become comparable to or less than those for pair production. We compute Monte Carlo spectral models for PSR1509-58. We find that photon splitting, or combined splitting and pair production, can explain the unusually low cutoff energy (between 2 and 30 MeV) of PSR1...

  17. Constraining Very Heavy Dark Matter Using Diffuse Backgrounds of Neutrinos and Cascaded Gamma Rays

    CERN Document Server

    Murase, Kohta

    2012-01-01

    We consider multi-messenger constraints on very heavy dark matter (VHDM) from recent Fermi gamma-ray and IceCube neutrino observations of isotropic background radiation. Fermi data on the diffuse gamma-ray background (DGB) shows a possible unexplained feature at very high energies (VHE), which we have called the VHE Excess relative to expectations for an attenuated power law extrapolated from lower energies. We show that VHDM could explain this excess, and that neutrino observations will be an important tool for testing this scenario. More conservatively, we derive new constraints on the properties of VHDM for masses of 10^3-10^10 GeV. These generic bounds follow from cosmic energy budget constraints for gamma rays and neutrinos that we developed elsewhere, based on detailed calculations of cosmic electromagnetic cascades and also neutrino detection rates. We show that combining both gamma-ray and neutrino data is essential for making the constraints on VHDM properties both strong and robust. In the lower mas...

  18. A photon splitting cascade model of soft gamma-ray repeaters

    CERN Document Server

    Harding, A K; Harding, Alice K; Baring, Matthew G

    1996-01-01

    The spectra of soft gamma-ray repeaters (SGRs), with the exception of the March 5, 1979 main burst, are characterized by high-energy cutoffs around 30 keV and low-energy turnovers that are much steeper than a Wien spectrum. Baring (1995) found that the spectra of cascades due to photon splitting in a very strong, homogeneous magnetic field can soften spectra and produce good fits to the soft spectra of SGRs. Magnetic field strengths somewhat above the QED critical field strength B_{\\rm cr}, where B_{\\rm cr} = 4.413 \\times 10^{13} G, is required to produce cutoffs at 30-40 keV. We have improved upon this model by computing Monte Carlo photon splitting cascade spectra in a neutron star dipole magnetic field, including effects of curved space-time in a Schwarzschild metric. We investigate spectra produced by photons emitted at different locations and observer angles. We find that the general results of Baring hold for surface emission throughout most of the magnetosphere, but that emission in equatorial regions ...

  19. Search for neutrino-induced cascades from gamma-ray bursts with AMANDA

    CERN Document Server

    Achterberg, A; Adams, J; Ahrens, J; Andeen, K; Auffenberg, J; Bahcall, J N; Bai, X; Baret, B; Barwick, S W; Bay, R; Beattie, K; Becka, T; Becker, J K; Becker, K H; Berghaus, P; Berley, D; Bernardini, E; Bertrand, D; Besson, D Z; Blaufuss, E; Boersma, D J; Bohm, C; Bolmont, J; Boser, S; Botner, O; Bouchta, A; Braun, J; Burgess, C; Burgess, T; Castermans, T; Chirkin, D; Christy, B; Clem, J; Cowen, D F; D'Agostino, M V; Davour, A; Day, C T; De Clercq, C; Demirors, L; Descamps, F; Desiati, P; De Young, T; Díaz-Veléz, J C; Dreyer, J; Dumm, J P; Duvoort, M R; Edwards, W R; Ehrlich, R; Eisch, J; Ellsworth, R W; Evenson, P A; Fadiran, O; Fazely, A R; Filimonov, K; Foerster, M M; Fox, B D; Franckowiak, A; Gaisser, T K; Gallagher, J; Ganugapati, R; Geenen, H; Gerhardt, L; Goldschmidt, A; Goodman, J A; Gozzini, R; Griesel, T; Grullon, S; Gro, A; Gunasingha, R M; Gurtner, M; Hallgren, A; Halzen, F; Han, K; Hanson, K; Hardtke, D; Hardtke, R; Hart, J E; Hasegawa, Y; Hauschildt, T; Hays, D; Heise, J; Helbing, K; Hellwig, M; Herquet, P; Hill, G C; Hodges, J; Hoffman, K D; Hommez, B; Hoshina, K; Hubert, D; Hughey, B; Hulth, P O; Hultqvist, K; Hul, J P; Hundertmark, S; Inaba, M; Ishihara, A; Jacobsen, J; Japaridze, G S; Johansson, H; Jones, A; Joseph, J M; Kampert, K H; Karg, T; Karle, A; Kawai, H; Kelley, J L; Kitamura, N; Klein, S R; Klepser, S; Kohnen, G; Kolanoski, H; Köpke, L; Kowalski, M; Kowarik, T; Krasberg, M; Kühn, K; Labare, M; Landsman, H; Leich, H; Leier, D; Liubarsky, I; Lundberg, J; Lunemann, J; Madsen, J; Mase, K; Matis, H S; McCauley, T; McParland, C P; Meli, A; Messarius, T; Mészáros, P; Miyamoto, H; Mokhtarani, A; Montaruli, T; Morey, A; Morse, R; Movit, S M; Munich, K; Nahnhauer, R; Nam, J W; Nieen, P; Nygren, D R; Ogelman, H; Olivas, A; Patton, S; Peña-Garay, C; Pérez de los Heros, C; Piegsa, A; Pieloth, D; Pohl, A C; Porrata, R; Pretz, J; Price, P B; Przybylski, G T; Rawlins, K; Razzaque, S; Resconi, E; Rhode, W; Ribordy, M; Rizzo, A; Robbins, S; Roth, P; Rott, C; Rutledge, D; Ryckbosch, D; Sander, H G; Sarkar, S; Schlenstedt, S; Schmidt, T; Schneider, D; Seckel, D; Semburg, B; Seo, S H; Seunarine, S; Silvestri, A; Smith, A J; Solarz, M; Song, C; Sopher, J E; Spiczak, G M; Spiering, C; Stamatikos, M; Stanev, T; Steffen, P; Stezelberger, T; Stokstad, R G; Stoufer, M C; Stoyanov, S; Strahler, E A; Straszheim, T; Sulanke, K H; Sullivan, G W; Sumner, T J; Taboada, I; Tarasova, O; Tepe, A; Thollander, L; Tilav, S; Tluczykont, M; Toale, P A; Turcan, D; van Eijndhoven, N; Vandenbroucke, J; Van Overloop, A; Viscomi, V; Voigt, B; Wagner, W; Walck, C; Waldmann, H; Walter, M; Wang, Y R; Wendt, C; Wiebusch, C; Wikström, G; Williams, D R; Wischnewski, R; Wissing, H; Woschnagg, K; Xu, X W; Yodh, G; Yoshida, S; De Dios-Zornoza-Gomez, Juan

    2007-01-01

    Using the neutrino telescope AMANDA-II, we have conducted two analyses searching for neutrino-induced cascades from gamma-ray bursts. No evidence of astrophysical neutrinos was found, and limits are presented for several models. We also present neutrino effective areas which allow the calculation of limits for any neutrino production model. The first analysis looked for a statistical excess of events within a sliding window of 1 or 100 seconds (for short and long burst classes, respectively) during the years 2001-2003. The resulting upper limit on the diffuse flux normalization times E^2 for the Waxman-Bahcall model at 1 PeV is 1.6 x 10^-6 GeV cm^-2 s^-1 sr^-1. For this search 90% of the neutrinos would fall in the energy range 50 TeV to 7 PeV. The second analysis looked for neutrino-induced cascades in coincidence with 73 bursts detected by BATSE in the year 2000. The resulting upper limit on the diffuse flux normalization times E^2, also at 1 PeV, is 1.5 x 10^-6 GeV cm^-2 s^-1 sr^-1 for the same energy rang...

  20. A Measurement of the Branching Ratio and Asymmetry of the Decay Cascade$^{0} \\to \\Sigma ^{0}/gamma$

    CERN Document Server

    Alavi-Harati, A; Arenton, M; Arisaka, K; Averitte, S; Barker, A R; Bellantoni, L; Bellavance, A; Belz, J E; Ben-David, R; Bergman, D R; Blucher, E; Bock, G J; Bown, C; Bright, S T; Cheu, E; Childress, S; Coleman, R; Corcoran, M D; Corti, G; Cox, B; Crisler, M B; Erwin, A R; Ford, R; Glazov, A; Golossanov, A; Graham, G; Graham, J; Hagan, K; Halkiadakis, E; Hamm, J; Hanagaki, K; Hidaka, S; Hsiung, Y B; Jejer, V; Jensen, D A; Kessler, R; Kobrak, H G E; La Due, J; Lath, A; Ledovskoy, A A; McBride, P; Mikelsons, P; Monnier, E; Nakaya, T; Nelson, K S; Nguyen, H; O'Dell, Vivian R; Pang, M; Pordes, R; Prasad, V; Quinn, B; Ramberg, E J; Ray, R E; Roodman, A; Sadamoto, M; Schnetzer, S R; Senyo, K; Shanahan, P; Shawhan, P S; Shields, J; Slater, W; Solomey, Nickolas; Somalwar, S V; Stone, R L; Suzuki, I; Swallow, E C; Taegar, S A; Tesarek, R J; Thomson, G B; Toale, P A; Tripathi, A K; Tschirhart, R S; Turner, S E; Wah, Y W; Wang, J; White, H B; Whitmore, J; Winstein, Bruce D; Winston, R; Yamanaka, T; Zimmerman, E D

    2001-01-01

    We have studied the rare weak radiative hyperon decay Cascade0-->Sigma0/gamma in the KTeV experiment at Fermilab. We have identified 4045 signal events over a background of 804 events. The dominant Cascade0-->Lambda/pi0 decay, which was used for normalization, is the only important background source. An analysis of the acceptance of both modes yields a branching ratio of BR(Cascade0-->Sigma0/gamma)=(3.34 +/- 0.05 +/- 0.09) x 10^(-3). By analyzing the final state decay distributions, we have also determined that the Sigma0 emission asymmetry parameter for this decay is alpha = -0.63 +/- 0.09.

  1. Application of the EXtrapolated Efficiency Method (EXEM) to infer the gamma-cascade detection efficiency in the actinide region

    CERN Document Server

    Ducasse, Q; Mathieu, L; Marini, P; Morillon, B; Aiche, M; Tsekhanovich, I

    2015-01-01

    The study of transfer-induced gamma-decay probabilities is very useful for understanding the surrogate-reaction method and, more generally, for constraining statistical-model calculations. One of the main difficulties in the measurement of gamma-decay probabilities is the determination of the gamma-cascade detection efficiency. In [Nucl. Instrum. Meth. A 700, 59 (2013)] we developed the Extrapolated Efficiency Method (EXEM), a new method to measure this quantity. In this work, we have applied, for the first time, the EXEM to infer the gamma-cascade detection efficiency in the actinide region. In particular, we have considered the 238U(d,p)239U and 238U(3He,d)239Np reactions. We have performed Hauser-Feshbach calculations to interpret our results and to verify the hypothesis on which the EXEM is based. The determination of fission and gamma-decay probabilities of 239Np below the neutron separation energy allowed us to validate the EXEM.

  2. $\\gamma$-ray and X-ray luminosities from spin-powered pulsars in the full polar cap cascade model

    CERN Document Server

    Zhang, B; Zhang, Bing; Harding, Alice K.

    2000-01-01

    We modify the conventional curvature radiation (inverse Compton scattering) + synchrotron radiation polar cap cascade model by including the inverse Compton scattering of the higher generation pairs. Within the framework of the space-charge-limited-flow acceleration model with frame-dragging proposed by Harding & Muslimov (1998), such a full polar cap cascade scenario can well reproduce the $L_\\gamma \\propto (L_{\\rm sd})^{1/2}$ and the $L_x \\sim 10^{-3} L_{\\rm sd}$ dependences observed from the known spin-powered pulsars. According to this model, the ``pulsed'' soft ROSAT-band X-rays from most of the millisecond pulsars might be of thermal origin, if there are no strong multipole magnetic components near their surfaces.

  3. Correction technique for cascade gammas in I-124 imaging on a fully-3D, Time-of-Flight PET Scanner.

    Science.gov (United States)

    Surti, Suleman; Scheuermann, Ryan; Karp, Joel S

    2009-06-01

    It has been shown that I-124 PET imaging can be used for accurate dose estimation in radio-immunotherapy techniques. However, I-124 is not a pure positron emitter, leading to two types of coincidence events not typically encountered: increased random coincidences due to non-annihilation cascade photons, and true coincidences between an annihilation photon and primarily a coincident 602 keV cascade gamma (true coincidence gamma-ray background). The increased random coincidences are accurately estimated by the delayed window technique. Here we evaluate the radial and time distributions of the true coincidence gamma-ray background in order to correct and accurately estimate lesion uptake for I-124 imaging in a time-of-flight (TOF) PET scanner. We performed measurements using a line source of activity placed in air and a water-filled cylinder, using F-18 and I-124 radio-isotopes. Our results show that the true coincidence gamma-ray backgrounds in I-124 have a uniform radial distribution, while the time distribution is similar to the scattered annihilation coincidences. As a result, we implemented a TOF-extended single scatter simulation algorithm with a uniform radial offset in the tail-fitting procedure for accurate correction of TOF data in I-124 imaging. Imaging results show that the contrast recovery for large spheres in a uniform activity background is similar in F-18 and I-124 imaging. There is some degradation in contrast recovery for small spheres in I-124, which is explained by the increased positron range, and reduced spatial resolution, of I-124 compared to F-18. Our results show that it is possible to perform accurate TOF based corrections for I-124 imaging.

  4. Full polar cap cascade scenario $\\gamma$-ray and X-ray luminosities from spin-powered pulsars

    CERN Document Server

    Zhang, B; Zhang, Bing; Harding, Alice K.

    2000-01-01

    We modify polar cap cascade picture to include the ICS of the higher generation pairs. In such a ``full-cascade'' scenario, not only the perpendicular portion of the energy of the pairs goes to high energy radiation via SR, but the parallel portion of the energy of the pairs can also contribute to high energy emission via ICS with the soft thermal photons from either the full neutron star surface or the hot polar cap. An important output of such a scenario is that the soft tail of the ICS spectrum can naturally result in a non-thermal X-ray component which can contribute to the luminosities observed by ROSAT and ASCA. Here we present an analytic description of such a full polar cap cascade scenario within the framework of Harding & Muslimov acceleration model. We present the theoretical predictions of the $\\gamma$-ray luminosities, the thermal and non-thermal X-ray luminosities for the known spin-powered X-ray pulsars. Our results show that the observed different dependences of the high energy luminositie...

  5. Measurement of the radiative branching ratio for the Hoyle state using cascade gamma decays

    Directory of Open Access Journals (Sweden)

    Alshahrani B.

    2013-12-01

    Full Text Available A new setup consisting of four 5” by 5” NaI scintillators and an array of particle detectors is being developed. Proton-gamma-gamma coincidences will be measured using the 12C(p, p′12C reaction at 10.5 MeV energy. The new setup will be used for the measurement of the electromagnetic decay rate of the Hoyle state via two E2 transitions. We report the initial experimental results for singles gamma and gamma-proton coincidences through inelastic scattering of protons on a 12C target.

  6. Gamma-Ray and Neutrino Backgrounds as Probes of the High-Energy Universe: Hints of Cascades, General Constraints, and Implications for TeV Searches

    CERN Document Server

    Murase, Kohta; Takami, Hajime

    2012-01-01

    Recent observations of isotropic diffuse backgrounds by Fermi and IceCube allow us to get more insight into distant very-high-energy (VHE) and ultra-high-energy (UHE) gamma-ray/neutrino emitters, including cosmic-ray accelerators/sources. First, we investigate the contribution of intergalactic cascades induced by gamma-rays and/or cosmic rays (CRs) to the diffuse gamma-ray background (DGB) in view of the latest Fermi data. We identify a possible VHE Excess from the fact that the Fermi data are well above expectations for an attenuated power law, and show that cascades induced by VHE gamma rays (above ~10 TeV) and/or VHECRs (below ~10^19 eV) may significantly contribute to the DGB above ~100 GeV. The relevance of the cascades is also motivated by the intergalactic cascade interpretations of extreme TeV blazars such as 1ES 0229+200, which suggest very hard intrinsic spectra. This strengthens the importance of future detailed VHE DGB measurements. Then, more conservatively, we derive general constraints on the c...

  7. U-238 Neutron Capture Gamma Cascade Generation and Transport Simulation for Capture Tank Response

    Science.gov (United States)

    1992-05-07

    6 1.3 Calculations of Yamamuro et al. .. .. .. .. .. ... ... ... .... 9 1.6 Review of Primary Experimental Work .. .. .. .. ... ... .... 10 1.6.1...modeling has been performed by Booth et al. 󈨋, Takahashi [8], and Yamamuro et al. ŝ 1. Experimental results are found in the work of Campion et al. 7101...quantity in the calcu- lation of the gamma-ray spectrum. In the Yamamuro paper, the Fermi-gas model formula is used and is referred to as the partial level

  8. Parameters of the 125Te compound state cascade gamma-decay

    CERN Document Server

    Bondarenko, V A; Khitrov, V A; Sukhovoj, A M; Tomandl, I

    2005-01-01

    Reliable information on level density and radiative strength functions for the excitation energy region with density of excited states more than 100 levels per 1 MeV and higher can be obtained now only by its model-free extraction from intensities of two-step cascades proceeding between compound states and few low-lying levels. Full model-free determination of these parameters in any method is possible only if one can extract from additional experimental information about general trend in dependence of ratio of strength functions of emitted reaction products of a given type on excitation energy of the nucleus under study. Analysis of the available experimental data for 125Te shows that the peculiarities observed earlier in other nuclei are also inherent to this nucleus.

  9. Covariance analysis of selection rules governing the gamma-decay cascades of the rotational nucleus sup 1 sup 6 sup 4 Yb

    CERN Document Server

    Leoni, S; Bracco, A; Frattini, S; Montingelli, G; Vigezzi, E; Bergström, M H; Hagemann, G B; Herskind, B; Matsuo, M

    2000-01-01

    The gamma-cascades feeding specific intrinsic configurations of sup 1 sup 6 sup 4 Yb are studied making use of a statistical analysis of counts fluctuations in gamma-gamma coincident spectra. In particular, variance and covariance spectra are obtained starting from the measured (0,+), (0,-) and (1,-) gate-selected matrices. The analysis of the first ridge of the spectra yields about 25 excited bands carrying rotational energy correlations for the total spectrum, and about 10 in coincidence with each of the (alpha,pi) configurations. The covariance of count fluctuations between the different (alpha,pi) gates is expressed by an experimental correlation coefficient, r, which measures the degree of sharing of decay paths through the excited bands, and thereby the extent to which selection rules are obeyed by the decay. The correlation coefficient is around r approx 0.3 for the ridge, and also in general rather small for valley fluctuations. Only at the highest valley energies, a tendency to larger correlation coe...

  10. Possibilities to verify the level density and radiative strength functions, extracted from the two-step gamma-cascade intensities

    OpenAIRE

    2007-01-01

    The direct determination of the excitation level density and radiative strength functions of their exciting gamma-transitions is impossible for the larger part of the stable and long-life radioactive target nuclei. This circumstance is uniquely determined by the fact, that the level spacing much less than the resolution of the existing spectrometers of gamma-rays and charged particles. The extraction of these parameters of nucleus in this situation can be executed by their only fitting to the...

  11. Possibilities to verify the level density and radiative strength functions, extracted from the two-step gamma-cascade intensities

    CERN Document Server

    Khitrov, V A; Khang, Pham Dinh; Tan, Vuong Huu; Hai, Nguyen Xuan

    2007-01-01

    The direct determination of the excitation level density and radiative strength functions of their exciting gamma-transitions is impossible for the larger part of the stable and long-life radioactive target nuclei. This circumstance is uniquely determined by the fact, that the level spacing much less than the resolution of the existing spectrometers of gamma-rays and charged particles. The extraction of these parameters of nucleus in this situation can be executed by their only fitting to the most probable values, reproducing the measured in the nuclear reactions spectra and sections. This inverse problem of mathematical analysis of its nature is principally ambiguous. Moreover, system of equations, those connecting the number of excitable levels and probability of the emission of charge particles are assigned usually within the framework of some assumptions about the mechanism of nuclear reaction and factors, determining the dynamics of the studied process. The verification of these parameters can be partial...

  12. Biphasic Chromatin Structure and FISH Signals Reflect Intranuclear Order

    Directory of Open Access Journals (Sweden)

    Jyoti P. Chaudhuri

    2005-01-01

    Full Text Available Background and Aim: One of the two parental allelic genes may selectively be expressed, regulated by imprinting, X-inactivation or by other less known mechanisms. This study aims to reflect on such genetic mechanisms. Materials and Methods: Slides from short term cultures or direct smears of blood, bone marrow and amniotic fluids were hybridized with FISH probes singly, combined or sequentially. Two to three hundred cells were examined from each preparation. Results and Aignificance: A small number of cells (up to about 5%, more frequent in leukemia cases, showed the twin features: (1 nuclei with biphasic chromatin, one part decondensed and the other condensed; and (2 homologous FISH signals distributed equitably in those two regions. The biphasic chromatin structure with equitable distribution of the homologous FISH signals may correspond to the two sets of chromosomes, supporting observations on ploidywise intranuclear order. The decondensed chromatin may relate to enhanced transcriptions or advanced replications. Conclusions: Transcriptions of only one of the two parental genomes cause allelic exclusion. Genomes may switch with alternating monoallelic expression of biallelic genes as an efficient genetic mechanism. If genomes fail to switch, allelic exclusion may lead to malignancy. Similarly, a genome-wide monoallelic replication may tilt the balance of heterozygosity resulting in aneusomy, initiating early events in malignant transformation and in predicting cancer mortality.

  13. Neuronal intranuclear inclusions distinguish familial FTD-MND type from sporadic cases.

    Science.gov (United States)

    Mackenzie, Ian R A; Feldman, Howard

    2004-01-01

    Ubiquitin-immunoreactive (ub-ir) neuronal cytoplasmic inclusions are characteristically found in the extramotor cortex in patients with motor neuron disease (MND) and dementia (MND-dementia) and in a subset of patients with frontotemporal dementia (FTD) without motor symptoms (FTD-MND type). Recently, ub-ir neuronal intranuclear inclusions have been described in a small number of patients with familial FTD-MND type. To better define the sensitivity and specificity of this pathological change, we examined postmortem tissue from 14 patients with FTD-MND type (8 familial, 6 sporadic), 10 cases of MND-dementia (5 familial, 5 sporadic) and 19 cases of MND with no history of cognitive dysfunction (2 familial, 17 sporadic). Numerous intranuclear inclusions were found in multiple anatomic sites in 6/8 cases of familial FTD-MND. Rare intranuclear inclusions were present in the hippocampal dentate granule cells in 1 case of familial MND-dementia. No sporadic cases had intranuclear inclusions. These findings suggest that intranuclear inclusions are specific for familial FTD and may identify a subset of families with a common genetic basis. Although intranuclear inclusions are most characteristic of families with pure FTD, they may also be found in some pedigrees with both FTD and MND, further supporting the hypothesis that FTD-MND type and MND-dementia represent a clinicopathological spectrum of disease.

  14. Constraining the 6.05 MeV 0$^+$ and 6.13 MeV 3$^-$ cascade transitions in the $^{12}$C($\\alpha$,$\\gamma$)$^{16}$O reaction using the Asymptotic Normalization Coefficients

    CERN Document Server

    Avila, M L; Koshchiy, E; Baby, L T; Belarge, J; Kemper, K W; Kuchera, A N; Mukhamedzhanov, A M; Santiago-Gonzalez, D; Uberseder, E

    2014-01-01

    Background. The $^{12}$C($\\alpha,\\gamma$)$^{16}$O reaction plays a fundamental role in astrophysics because its cross section near 300 keV in c.m. determines the $^{12}$C/$^{16}$O ratio at the end of the helium burning stage of stellar evolution. The astrophysically desired accuracy of better than 10\\% has not been achieved. Cascade $\\gamma$ transitions through the excited states of $^{16}$O are contributing to the uncertainty. Purpose. To measure the Asymptotic Normalization Coefficients (ANCs) for the 0$^+$ (6.05 MeV) and 3$^-$ (6.13 MeV) excited states in $^{16}$O and provide constraints on the cross section for the corresponding cascade transitions. Method. The ANCs were measured using the $\\alpha$-transfer reaction $^{12}$C($^6$Li,$d$)$^{16}$O performed at sub-Coulomb energies for both the entrance and exit channels. Results. The ANCs for the 0$^+$(6.05 MeV), 3$^-$(6.13 MeV), 2$^+$(6.92 MeV) and 1$^-$(7.12 MeV) states in $^{16}$O have been measured. The contribution of the 0$^+$ and 3$^-$ cascade transit...

  15. Intranuclear Delivery of a Novel Antibody-Derived Radiosensitizer Targeting the DNA-Dependent Protein Kinase Catalytic Subunit

    Energy Technology Data Exchange (ETDEWEB)

    Xiong Hairong [Institute of Molecular Medicine and Genetics, Georgia Health Sciences University, Augusta, GA (Georgia); State Key Laboratory of Virology, Institute of Medical Virology, Wuhan University School of Medicine, Wuhan (China); Lee, Robert J. [Division of Pharmaceutics, College of Pharmacy, Ohio State University, Columbus, OH (United States); Haura, Eric B. [Thoracic Oncology and Experimental Therapeutics Programs, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (United States); Edwards, John G. [Apeliotus Technologies, Inc., Atlanta, GA (United States); Dynan, William S. [Institute of Molecular Medicine and Genetics, Georgia Health Sciences University, Augusta, GA (Georgia); Li Shuyi, E-mail: sli@georgiahealth.edu [Institute of Molecular Medicine and Genetics, Georgia Health Sciences University, Augusta, GA (Georgia); Apeliotus Technologies, Inc., Atlanta, GA (United States)

    2012-07-01

    Purpose: To inhibit DNA double-strand break repair in tumor cells by delivery of a single-chain antibody variable region fragment (ScFv 18-2) to the cell nucleus. ScFv 18-2 binds to a regulatory region of the DNA-dependent protein kinase (DNA-PK), an essential enzyme in the nonhomologous end-joining pathway, and inhibits DNA end-joining in a cell-free system and when microinjected into single cells. Development as a radiosensitizer has been limited by the lack of a method for intranuclear delivery to target cells. We investigated a delivery method based on folate receptor-mediated endocytosis. Methods and Materials: A recombinant ScFv 18-2 derivative was conjugated to folate via a scissile disulfide linker. Folate-ScFv 18-2 was characterized for its ability to be internalized by tumor cells and to influence the behavior of ionizing radiation-induced repair foci. Radiosensitization was measured in a clonogenic survival assay. Survival curves were fitted to a linear-quadratic model, and between-group differences were evaluated by an F test. Sensitization ratios were determined based on mean inhibitory dose. Results: Human KB and NCI-H292 lung cancer cells treated with folate-conjugated ScFv 18-2 showed significant radiosensitization (p < 0.001). Sensitization enhancement ratios were 1.92 {+-} 0.42 for KB cells and 1.63 {+-} 0.13 for NCI-H292 cells. Studies suggest that treatment inhibits repair of radiation-induced DSBs, as evidenced by the persistence of {gamma}-H2AX-stained foci and by inhibition of staining with anti-DNA-PKcs phosphoserine 2056. Conclusions: Folate-mediated endocytosis is an effective method for intranuclear delivery of an antibody-derived DNA repair inhibitor.

  16. Actin-Interacting Protein 1 Contributes to Intranuclear Rod Assembly in Dictyostelium discoideum

    Science.gov (United States)

    Ishikawa-Ankerhold, Hellen C.; Daszkiewicz, Wioleta; Schleicher, Michael; Müller-Taubenberger, Annette

    2017-01-01

    Intranuclear rods are aggregates consisting of actin and cofilin that are formed in the nucleus in consequence of chemical or mechanical stress conditions. The formation of rods is implicated in a variety of pathological conditions, such as certain myopathies and some neurological disorders. It is still not well understood what exactly triggers the formation of intranuclear rods, whether other proteins are involved, and what the underlying mechanisms of rod assembly or disassembly are. In this study, Dictyostelium discoideum was used to examine appearance, stages of assembly, composition, stability, and dismantling of rods. Our data show that intranuclear rods, in addition to actin and cofilin, are composed of a distinct set of other proteins comprising actin-interacting protein 1 (Aip1), coronin (CorA), filactin (Fia), and the 34 kDa actin-bundling protein B (AbpB). A finely tuned spatio-temporal pattern of protein recruitment was found during formation of rods. Aip1 is important for the final state of rod compaction indicating that Aip1 plays a major role in shaping the intranuclear rods. In the absence of both Aip1 and CorA, rods are not formed in the nucleus, suggesting that a sufficient supply of monomeric actin is a prerequisite for rod formation. PMID:28074884

  17. Oxidative DNA Damage Mediated by Intranuclear MMP Activity Is Associated with Neuronal Apoptosis in Ischemic Stroke.

    Science.gov (United States)

    Kimura-Ohba, Shihoko; Yang, Yi

    2016-01-01

    Evidence of the pathological roles of matrix metalloproteinases (MMPs) in various neurological disorders has made them attractive therapeutic targets. MMPs disrupt the blood-brain barrier and cause neuronal death and neuroinflammation in acute cerebral ischemia and are critical for angiogenesis during recovery. However, some challenges have to be overcome before MMPs can be further validated as drug targets in stroke injury. Identifying in vivo substrates of MMPs should greatly improve our understanding of the mechanisms of ischemic injury and is critical for providing more precise drug targets. Recent works have uncovered nontraditional roles for MMPs in the cytosol and nucleus. These have shed light on intracellular targets and biological actions of MMPs, adding additional layers of complexity for therapeutic MMP inhibition. In this review, we discussed the recent advances made in understanding nuclear location of MMPs, their regulation of intranuclear sorting, and their intranuclear proteolytic activity and substrates. In particular, we highlighted the roles of intranuclear MMPs in oxidative DNA damage, neuronal apoptosis, and neuroinflammation at an early stage of stroke insult. These novel data point to new putative MMP-mediated intranuclear actions in stroke-induced pathological processes and may lead to novel approaches to treatment of stroke and other neurological diseases.

  18. Oxidative DNA Damage Mediated by Intranuclear MMP Activity Is Associated with Neuronal Apoptosis in Ischemic Stroke

    Directory of Open Access Journals (Sweden)

    Shihoko Kimura-Ohba

    2016-01-01

    Full Text Available Evidence of the pathological roles of matrix metalloproteinases (MMPs in various neurological disorders has made them attractive therapeutic targets. MMPs disrupt the blood-brain barrier and cause neuronal death and neuroinflammation in acute cerebral ischemia and are critical for angiogenesis during recovery. However, some challenges have to be overcome before MMPs can be further validated as drug targets in stroke injury. Identifying in vivo substrates of MMPs should greatly improve our understanding of the mechanisms of ischemic injury and is critical for providing more precise drug targets. Recent works have uncovered nontraditional roles for MMPs in the cytosol and nucleus. These have shed light on intracellular targets and biological actions of MMPs, adding additional layers of complexity for therapeutic MMP inhibition. In this review, we discussed the recent advances made in understanding nuclear location of MMPs, their regulation of intranuclear sorting, and their intranuclear proteolytic activity and substrates. In particular, we highlighted the roles of intranuclear MMPs in oxidative DNA damage, neuronal apoptosis, and neuroinflammation at an early stage of stroke insult. These novel data point to new putative MMP-mediated intranuclear actions in stroke-induced pathological processes and may lead to novel approaches to treatment of stroke and other neurological diseases.

  19. Disruption of NAD~+ binding site in glyceraldehyde 3-phosphate dehydrogenase affects its intranuclear interactions

    Institute of Scientific and Technical Information of China (English)

    Manali; Phadke; Natalia; Krynetskaia; Anurag; Mishra; Carlos; Barrero; Salim; Merali; Scott; A; Gothe; Evgeny; Krynetskiy

    2015-01-01

    AIM:To characterize phosphorylation of human glyceraldehyde 3-phosphate dehydrogenase(GAPDH),and mobility of GAPDH in cancer cells treated with chemotherapeutic agents. METHODS:We used proteomics analysis to detect and characterize phosphorylation sites within human GAPDH. Site-specific mutagenesis and alanine scanning was then performed to evaluate functional significance of phosphorylation sites in the GAPDH polypeptide chain. Enzymatic properties of mutated GAPDH variants were assessed using kinetic studies. Intranuclear dynamics parameters(diffusion coefficient and the immobile fraction) were estimated using fluorescence recovery after photobleaching(FRAP) experiments and confocal microscopy. Molecular modeling experiments were performed to estimate the effects of mutations on NAD+ cofactor binding.RESULTS:Using MALDI-TOF analysis,we identified novel phosphorylation sites within the NAD+ binding center of GAPDH at Y94,S98,and T99. Using polyclonal antibody specific to phospho-T99-containing peptide within GAPDH,we demonstrated accumulation of phospho-T99-GAPDH inthe nuclear fractions of A549,HCT116,and SW48 cancer cel s after cytotoxic stress. We performed site-mutagenesis,and estimated enzymatic properties,intranuclear distribution,and intranuclear mobility of GAPDH mutated variants. Site-mutagenesis at positions S98 and T99 in the NAD+ binding center reduced enzymatic activity of GAPDH due to decreased affinity to NAD+(Km = 741 ± 257 μmol/L in T99 I vs 57 ± 11.1 μmol/L in wild type GAPDH. Molecular modeling experiments revealed the effect of mutations on NAD+ binding with GAPDH. FRAP(fluorescence recovery after photo bleaching) analysis showed that mutations in NAD+ binding center of GAPDH abrogated its intranuclear interactions. CONCLUSION:Our results suggest an important functional role of phosphorylated amino acids in the NAD+ binding center in GAPDH interactions with its intranuclear partners.

  20. Time evolution of cascade decay

    CERN Document Server

    Boyanovsky, Daniel

    2014-01-01

    We study non-perturbatively the time evolution of cascade decay for generic fields $\\pi \\rightarrow \\phi_1\\phi_2\\rightarrow \\phi_2\\chi_1\\chi_2$ and obtain the time dependence of amplitudes and populations for the resonant and final states. We analyze in detail the different time scales and the manifestation of unitary time evolution in the dynamics of production and decay of resonant intermediate and final states. The probability of occupation (population) ``flows'' as a function of time from the initial to the final states. When the decay width of the parent particle $\\Gamma_\\pi$ is much larger than that of the intermediate resonant state $\\Gamma_{\\phi_1}$ there is a ``bottleneck'' in the flow, the population of resonant states builds up to a maximum at $t^* = \\ln[\\Gamma_\\pi/\\Gamma_{\\phi_1}]/(\\Gamma_\\pi-\\Gamma_{\\phi_1})$ nearly saturating unitarity and decays to the final state on the longer time scale $1/\\Gamma_{\\phi_1}$. As a consequence of the wide separation of time scales in this case the cascade decay ...

  1. Survival and Intra-Nuclear Trafficking of Burkholderia pseudomallei: Strategies of Evasion from Immune Surveillance?

    Science.gov (United States)

    Vadivelu, Jamuna; Vellasamy, Kumutha Malar; Thimma, Jaikumar; Mariappan, Vanitha; Kang, Wen-Tyng; Choh, Leang-Chung; Wong, Kum Thong

    2017-01-01

    Background During infection, successful bacterial clearance is achieved via the host immune system acting in conjunction with appropriate antibiotic therapy. However, it still remains a tip of the iceberg as to where persistent pathogens namely, Burkholderia pseudomallei (B. pseudomallei) reside/hide to escape from host immune sensors and antimicrobial pressure. Methods We used transmission electron microscopy (TEM) to investigate post-mortem tissue sections of patients with clinical melioidosis to identify the localisation of a recently identified gut microbiome, B. pseudomallei within host cells. The intranuclear presence of B. pseudomallei was confirmed using transmission electron microscopy (TEM) of experimentally infected guinea pig spleen tissues and Live Z-stack, and ImageJ analysis of fluorescence microscopy analysis of in vitro infection of A549 human lung epithelial cells. Results TEM investigations revealed intranuclear localization of B. pseudomallei in cells of infected human lung and guinea pig spleen tissues. We also found that B. pseudomallei induced actin polymerization following infection of A549 human lung epithelial cells. Infected A549 lung epithelial cells using 3D-Laser scanning confocal microscopy (LSCM) and immunofluorescence microscopy confirmed the intranuclear localization of B. pseudomallei. Conclusion B. pseudomallei was found within the nuclear compartment of host cells. The nucleus may play a role as an occult or transient niche for persistence of intracellular pathogens, potentially leading to recurrrent episodes or recrudescence of infection. PMID:28045926

  2. Learning Cascading

    CERN Document Server

    Covert, Michael

    2015-01-01

    This book is intended for software developers, system architects and analysts, big data project managers, and data scientists who wish to deploy big data solutions using the Cascading framework. You must have a basic understanding of the big data paradigm and should be familiar with Java development techniques.

  3. Compartmentalization and Functionality of Nuclear Disorder: Intrinsic Disorder and Protein-Protein Interactions in Intra-Nuclear Compartments

    Directory of Open Access Journals (Sweden)

    Fanchi Meng

    2015-12-01

    Full Text Available The cell nucleus contains a number of membrane-less organelles or intra-nuclear compartments. These compartments are dynamic structures representing liquid-droplet phases which are only slightly denser than the bulk intra-nuclear fluid. They possess different functions, have diverse morphologies, and are typically composed of RNA (or, in some cases, DNA and proteins. We analyzed 3005 mouse proteins localized in specific intra-nuclear organelles, such as nucleolus, chromatin, Cajal bodies, nuclear speckles, promyelocytic leukemia (PML nuclear bodies, nuclear lamina, nuclear pores, and perinuclear compartment and compared them with ~29,863 non-nuclear proteins from mouse proteome. Our analysis revealed that intrinsic disorder is enriched in the majority of intra-nuclear compartments, except for the nuclear pore and lamina. These compartments are depleted in proteins that lack disordered domains and enriched in proteins that have multiple disordered domains. Moonlighting proteins found in multiple intra-nuclear compartments are more likely to have multiple disordered domains. Protein-protein interaction networks in the intra-nuclear compartments are denser and include more hubs compared to the non-nuclear proteins. Hubs in the intra-nuclear compartments (except for the nuclear pore are enriched in disorder compared with non-nuclear hubs and non-nuclear proteins. Therefore, our work provides support to the idea of the functional importance of intrinsic disorder in the cell nucleus and shows that many proteins associated with sub-nuclear organelles in nuclei of mouse cells are enriched in disorder. This high level of disorder in the mouse nuclear proteins defines their ability to serve as very promiscuous binders, possessing both large quantities of potential disorder-based interaction sites and the ability of a single such site to be involved in a large number of interactions.

  4. Cascading Cosmology

    CERN Document Server

    Agarwal, Nishant; Khoury, Justin; Trodden, Mark

    2009-01-01

    We develop a fully covariant, well-posed 5D effective action for the 6D cascading gravity brane-world model, and use this to study cosmological solutions. We obtain this effective action through the 6D decoupling limit, in which an additional scalar degree mode, \\pi, called the brane-bending mode, determines the bulk-brane gravitational interaction. The 5D action obtained this way inherits from the sixth dimension an extra \\pi self-interaction kinetic term. We compute appropriate boundary terms, to supplement the 5D action, and hence derive fully covariant junction conditions and the 5D Einstein field equations. Using these, we derive the cosmological evolution induced on a 3-brane moving in a static bulk. We study the strong- and weak-coupling regimes analytically in this static ansatz, and perform a complete numerical analysis of our solution. Although the cascading model can generate an accelerating solution in which the \\pi field comes to dominate at late times, the presence of a critical singularity prev...

  5. Karyomegaly and intranuclear inclusions in the renal tubules of sentinel ICR mice (mus musculus).

    Science.gov (United States)

    Baze, Wallace B; Steinbach, Thomas J; Fleetwood, Michelle L; Blanchard, Terrell W; Barnhart, Kirstin F; McArthur, Mark J

    2006-10-01

    Among 585 sentinel ICR mice (Mus musculus), 8 (7 female, 1 male) had unusual microscopic lesions in the kidney. Light microscopy revealed occasional tubular epithelial cells with large, karyomegalic nuclei that contained intranuclear inclusions and marginated chromatin. These cells were randomly present in the cortex and medulla but were more prominent near the corticomedullary junc tion. Rare pyknotic cells and mild interstitial infiltrates of lymphocytes and plasma cells were associated with occasional foci of abnormal cells. Electron microscopy performed on 2 (1 female, 1 male) of the mice demonstrated intranuclear inclusions composed of abundant flocculent, electron-lucent material. No viral particles or other pathogens were identified. General health monitoring that included serology, microbiology, parasitology, necropsy, and histopathology was negative for pathogens. Polymerase chain reaction-based testing for polyomavirus and immunohistochemistry for adenovirus were performed on 5 of the 7 female mice; all were negative for both viruses. In light of microscopy findings and the lack of evidence for an infectious agent, the tubular lesions were considered degenerative changes, possibly due to a toxic insult. The cause and significance of the findings in these mice can not be explained fully.

  6. Protein complex formation and intranuclear dynamics of NAC1 in cancer cells.

    Science.gov (United States)

    Nakayama, Naomi; Kato, Hiroaki; Sakashita, Gyosuke; Nariai, Yuko; Nakayama, Kentaro; Kyo, Satoru; Urano, Takeshi

    2016-09-15

    Nucleus accumbens-associated protein 1 (NAC1) is a cancer-related transcription regulator protein that is also involved in the pluripotency and differentiation of embryonic stem cells. NAC1 is overexpressed in various carcinomas including ovarian, cervical, breast, and pancreatic carcinomas. NAC1 knock-down was previously shown to result in the apoptosis of ovarian cancer cell lines and to rescue their sensitivity to chemotherapy, suggesting that NAC1 may be a potential therapeutic target, but protein complex formation and the dynamics of intranuclear NAC1 in cancer cells remain poorly understood. In this study, analysis of HeLa cell lysates by fast protein liquid chromatography (FPLC) on a sizing column showed that the NAC1 peak corresponded to an apparent molecular mass of 300-500 kDa, which is larger than the estimated molecular mass (58 kDa) of the protein. Furthermore, live cell photobleaching analyses with green fluorescent protein (GFP)-fused NAC1 proteins revealed the intranuclear dynamics of NAC1. Collectively our results demonstrate that NAC1 forms a protein complex to function as a transcriptional regulator in cancer cells.

  7. THERMOSTABILITY OF A NUCLEAR-TARGETED LUCIFERASE EXPRESSED IN MAMMALIAN-CELLS - DESTABILIZING INFLUENCE OF THE INTRANUCLEAR MICROENVIRONMENT

    NARCIS (Netherlands)

    MICHELS, AA; NGUYEN, VT; KONINGS, AW; KAMPINGA, HH; BENSAUDE, O

    1995-01-01

    Protein denaturation and aggregation are most likely the cause for the noxious effects of heat shock, There are some indications that the nucleus is one of the most sensitive cellular compartments, To test the possibility that the intranuclear microenvironment might be detrimental to the heat stabil

  8. The proteins of intra-nuclear bodies: a data-driven analysis of sequence, interaction and expression

    Directory of Open Access Journals (Sweden)

    Bodén Mikael

    2010-04-01

    Full Text Available Abstract Background Cajal bodies, nucleoli, PML nuclear bodies, and nuclear speckles are morpohologically distinct intra-nuclear structures that dynamically respond to cellular cues. Such nuclear bodies are hypothesized to play important regulatory roles, e.g. by sequestering and releasing transcription factors in a timely manner. While the nucleolus and nuclear speckles have received more attention experimentally, the PML nuclear body and the Cajal body are still incompletely characterized in terms of their roles and protein complement. Results By collating recent experimentally verified data, we find that almost 1000 proteins in the mouse nuclear proteome are known to associate with one or more of the nuclear bodies. Their gene ontology terms highlight their regulatory roles: splicing is confirmed to be a core activity of speckles and PML nuclear bodies house a range of proteins involved in DNA repair. We train support-vector machines to show that nuclear proteins contain discriminative sequence features that can be used to identify their intra-nuclear body associations. Prediction accuracy is highest for nucleoli and nuclear speckles. The trained models are also used to estimate the full protein complement of each nuclear body. Protein interactions are found primarily to link proteins in the nuclear speckles with proteins from other compartments. Cell cycle expression data provide support for increased activity in nucleoli, nuclear speckles and PML nuclear bodies especially during S and G2 phases. Conclusions The large-scale analysis of the mouse nuclear proteome sheds light on the functional organization of physically embodied intra-nuclear compartments. We observe partial support for the hypothesis that the physical organization of the nucleus mirrors functional modularity. However, we are unable to unambiguously identify proteins' intra-nuclear destination, suggesting that critical drivers behind of intra-nuclear translocation are yet to

  9. Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis.

    Directory of Open Access Journals (Sweden)

    Laure Franqueville

    Full Text Available Intranuclear crystalline inclusions have been observed in the nucleus of epithelial cells infected with Adenovirus serotype 5 (Ad5 at late steps of the virus life cycle. Using immuno-electron microscopy and confocal microscopy of cells infected with various Ad5 recombinants modified in their penton base or fiber domains, we found that these inclusions represented crystals of penton capsomers, the heteromeric capsid protein formed of penton base and fiber subunits. The occurrence of protein crystals within the nucleus of infected cells required the integrity of the fiber knob and part of the shaft domain. In the knob domain, the region overlapping residues 489-492 in the FG loop was found to be essential for crystal formation. In the shaft, a large deletion of repeats 4 to 16 had no detrimental effect on crystal inclusions, whereas deletion of repeats 8 to 21 abolished crystal formation without altering the level of fiber protein expression. This suggested a crucial role of the five penultimate repeats in the crystallisation process. Chimeric pentons made of Ad5 penton base and fiber domains from different serotypes were analyzed with respect to crystal formation. No crystal was found when fiber consisted of shaft (S from Ad5 and knob (K from Ad3 (heterotypic S5-K3 fiber, but occurred with homotypic S3K3 fiber. However, less regular crystals were observed with homotypic S35-K35 fiber. TB5, a monoclonal antibody directed against the Ad5 fiber knob was found by immunofluorescence microscopy to react with high efficiency with the intranuclear protein crystals in situ. Data obtained with Ad fiber mutants indicated that the absence of crystalline inclusions correlated with a lower infectivity and/or lower yields of virus progeny, suggesting that the protein crystals might be involved in virion assembly. Thus, we propose that TB5 staining of Ad-infected 293 cells can be used as a prognostic assay for the viability and productivity of fiber-modified Ad5

  10. Intranuclear interactomic inhibition of NF-κB suppresses LPS-induced severe sepsis

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sung-Dong [Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749 (Korea, Republic of); Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749 (Korea, Republic of); Cheon, So Yeong [Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul 120-752 (Korea, Republic of); Park, Tae-Yoon; Shin, Bo-Young [Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749 (Korea, Republic of); Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749 (Korea, Republic of); Oh, Hyunju; Ghosh, Sankar [Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032 (United States); Koo, Bon-Nyeo, E-mail: koobn@yuhs.ac [Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul 120-752 (Korea, Republic of); Lee, Sang-Kyou, E-mail: sjrlee@yonsei.ac.kr [Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749 (Korea, Republic of); Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749 (Korea, Republic of)

    2015-08-28

    Suppression of nuclear factor-κB (NF-κB) activation, which is best known as a major regulator of innate and adaptive immune responses, is a potent strategy for the treatment of endotoxic sepsis. To inhibit NF-κB functions, we designed the intra-nuclear transducible form of transcription modulation domain (TMD) of RelA (p65), called nt-p65-TMD, which can be delivered effectively into the nucleus without influencing the cell viability, and work as interactomic inhibitors via disruption of the endogenous p65-mediated transcription complex. nt-p65-TMD effectively inhibited the secretion of pro-inflammatory cytokines, including TNF-α, IL-1β, or IL-6 from BV2 microglia cells stimulated by lipopolysaccharide (LPS). nt-p65-TMD did not inhibit tyrosine phosphorylation of signaling mediators such as ZAP-70, p38, JNK, or ERK involved in T cell activation, but was capable of suppressing the transcriptional activity of NF-κB without the functional effect on that of NFAT upon T-cell receptor (TCR) stimulation. The transduced nt-p65-TMD in T cell did not affect the expression of CD69, however significantly inhibited the secretion of T cell-specific cytokines such as IL-2, IFN-γ, IL-4, IL-17A, or IL-10. Systemic administration of nt-p65-TMD showed a significant therapeutic effect on LPS-induced sepsis model by inhibiting pro-inflammatory cytokines secretion. Therefore, nt-p65-TMD can be a novel therapeutics for the treatment of various inflammatory diseases, including sepsis, where a transcription factor has a key role in pathogenesis, and further allows us to discover new functions of p65 under normal physiological condition without genetic alteration. - Highlights: • The nt-p65-TMD is intra-nuclear interactomic inhibitor of endogenous p65. • The nt-p65-TMD effectively inhibited the secretion of pro-inflammatory cytokines. • The excellent therapeutic potential of nt-p65-TMD was confirmed in sepsis model.

  11. Degeneração oxychromatica ("inclusões intranucleares" na febre amarella

    Directory of Open Access Journals (Sweden)

    C. Magarinos Torres

    1931-05-01

    ção oxychromatica (figs. 37 e 40; são escassos e de caracterisação duvidosa em virtude da concomitancia de alterações necrobíoticas não específicas. 2- Durante a epidemia de febre amarella em 1928 no Rio de Janeiro, notamos differenças assaz pronunciadas entre as lesões hepaticas no homem e no M. rhesus. Taes differenças, existindo em material assaz homogeneo quanto ás amostras de virus em questão, nos levam a concluir que a capacidade de formar corpusculos intranucleares especificos, como tambem a já conhecida permanencia do virus no sangue e nos tecidos, depende, de modo evidente, da especie animal usada e não da propria amostra empregada, nem do numero de passagens que ella soffreu no macaco. Embora os doentes pertencessem a raças differentes (quadro VIII e embora, possivelmente diversas amostras de virus tenham sido nelles inoculadas, estamos autorisados a concluir que a amostra ou amostras que infectaram o homem na epidemia de 1928, no Rio de janeiro, possuem nelle uma fraca capacidade de determinar inclusões intranucleares. Ao contrario, a mesma amostra ou amostras são capazes de produzir no M. rhesus, logo na primeira passagem, inclusões intranucleares assaz abundantes. Outra diferença que notamos e attribuimos a especie animal empregada foi; as alterações hepaticas de natureza toxica e circulatoria (congestão, necrose e necrobiose da cellula hepatica são nitidamente mais intensas no homem que nos macacos injectados com as amostras brasileiras do virus da febre amarella isoladas durante a epidemia de 1928 no Rio de Janeiro. Conseguimos, no homem, evidencia de inclusões typicas na cellula hepatica, apenas em tres casos dentre dezesete examinados. Esse resultado, provavelmente, ainda não é definitivo, indicando, apenas a raridade extrema que os corpusculos podem apresentar nos casos de febre amarella que ordinariamente chegam á autopsia. Tambem não realisamos uma pesquiza exhaustiva dos corpusculos em outros orgãos além do figado. O caso no qual

  12. Topochemistry of Internuclear and Intranuclear Interneurons of the Vasomotor Area in the Medulla Oblongata of Hypertensive Rats.

    Science.gov (United States)

    Chertok, V M; Kotsyuba, A E; Startseva, M S

    2016-01-01

    Immunohistochemical examination with the antiserum against neuronal NO synthase and cystathionine β-synthase was used to study the following two pools of interneurons in Wistar rats at various periods after the development of renovascular hypertension: intranuclear interneurons (lying in the projection of the solitary nucleus, reticular gigantocellular nucleus, and parvocellular nucleus) and 2 groups of internuclear interneurons (small interneurons, area 50-300 μ(2); and large interneurons, area above 350 μ(2)). Intranuclear and internuclear interneurons probably play a role in the central mechanisms of hemodynamics regulation. These interneurons differ by not only in topochemical parameters, but also functional properties (different resistances to BP changes). Intranuclear interneurons are characterized by high sensitivity of the gas transmitter systems to a continuous increase in BP, which results in remodeling and dysfunction of the bulbar part of the cardiovascular center. Large internuclear interneurons demonstrate a strong reaction to BP rise, which confirms their involvement into hemodynamics regulation. By contrast, small internuclear interneurons retain their characteristics in arterial hypertension and probably perform an integrative function.

  13. Intranuclear Inclusions in Renal Tubular Epithelium in Immunodeficient Mice Stain with Antibodies for Bovine Papillomavirus Type 1 L1 Protein

    Directory of Open Access Journals (Sweden)

    Elizabeth McInnes

    2015-06-01

    Full Text Available The kidneys from six immunodeficient mice examined by Cerberus Sciences and the Animal Resources Centre, displayed karyomegaly with pale eosinophilic, intranuclear inclusions upon histopathological examination. Electron microscopy performed on kidney tissue from 5/6 mice demonstrated margination of the chromatin in large nuclei. Laboratory tests were used to detect nucleic acid of papillomaviruses, polyomaviruses, circoviruses and anelloviruses (4/6 mice, a specific PCR was used to detect murine polyomavirus (1/6, and a panel of serological tests was used to detect seroconversion to major murine pathogens (1/6. All molecular and serological tests were negative. Immunohistochemistry using polyclonal anti-bovine papillomavirus type 1 (BPV-1 L1 antibody, Camvir monoclonal anti-papillomavirus antibody (directed against the seven amino acids GFGAMDF found in human papillomavirus (HPV 16 L1 protein, a commercially available mixture of two monoclonal antibodies, anti-BPV-1 L1/1H8 + Camvir antibodies, and a monoclonal anti-Hsc70 antibody revealed specific, positive staining of murine renal tubular epithelial intranuclear inclusions in 6/6 mice using the anti-BPV-1 L1 containing antibodies only. Methyl pyronin green, PAS and Feulgen histochemical reactions revealed that the intranuclear inclusions did not consist of RNA, DNA or carbohydrate. An immunohistochemical method now exists that can be used to confirm and evaluate suspected cases of murine inclusion body nephropathy.

  14. The CCFM Monte Carlo generator CASCADE 2.2.0

    CERN Document Server

    Jung, H; Deak, M; Grebenyuk, A; Hautmann, F; Hentschinski, M; Knutsson, A; Kraemer, M; Kutak, K; Lipatov, A; Zotov, N

    2010-01-01

    CASCADE is a full hadron level Monte Carlo event generator for ep, \\gamma p and p\\bar{p} and pp processes, which uses the CCFM evolution equation for the initial state cascade in a backward evolution approach supplemented with off - shell matrix elements for the hard scattering. A detailed program description is given, with emphasis on parameters the user wants to change and variables which completely specify the generated events.

  15. Familial frontotemporal dementia with neuronal intranuclear inclusions is not a polyglutamine expansion disease

    Directory of Open Access Journals (Sweden)

    Neal Scott J

    2006-08-01

    Full Text Available Abstract Background Many cases of frontotemporal dementia (FTD are familial, often with an autosomal dominant pattern of inheritance. Some are due to a mutation in the tau- encoding gene, on chromosome 17, and show an accumulation of abnormal tau in brain tissue (FTDP-17T. Most of the remaining familial cases do not exhibit tau pathology, but display neuropathology similar to patients with dementia and motor neuron disease, characterized by the presence of ubiquitin-immunoreactive (ub-ir, dystrophic neurites and neuronal cytoplasmic inclusions in the neocortex and hippocampus (FTLD-U. Recently, we described a subset of patients with familial FTD with autopsy-proven FTLD-U pathology and with the additional finding of ub-ir neuronal intranuclear inclusions (NII. NII are a characteristic feature of several other neurodegenerative conditions for which the genetic basis is abnormal expansion of a polyglutamine-encoding trinucleotide repeat region. The genetic basis of familial FTLD-U is currently not known, however the presence of NII suggests that a subset of cases may represent a polyglutamine expansion disease. Methods We studied DNA and post mortem brain tissue from 5 affected members of 4 different families with NII and one affected individual with familial FTLD-U without NII. Patient DNA was screened for CAA/CAG trinucleotide expansion in a set of candidate genes identified using a genome-wide computational approach. Genes containing CAA/CAG trinucleotide repeats encoding at least five glutamines were examined (n = 63, including the nine genes currently known to be associated with human disease. CAA/CAG tract sizes were compared with published normal values (where available and with those of healthy controls (n = 94. High-resolution agarose gel electrophoresis was used to measure allele size (number of CAA/CAG repeats. For any alleles estimated to be equal to or larger than the maximum measured in the control population, the CAA/CAG tract

  16. Probing cluster environments of blazars through gamma-gamma absorption

    CERN Document Server

    Sushch, Iurii

    2014-01-01

    Most blazars are known to be hosted in giant elliptic galaxies, but their cluster environments have not been thoroughly investigated. Cluster environments may contain radiation fields of low-energy photons created by nearby galaxies and/or stars in the intracluster medium that produce diffuse intracluster light. These radiation fields may absorb very high energy gamma rays ($E\\gtrsim100$ GeV; VHE) and trigger pair cascades with further production of subsequent generations of gamma rays with lower energies via inverse Compton scattering on surrounding radiation fields leaving a characteristic imprint in the observed spectral shape. The change of the spectral shape of the blazar reflects the properties of its ambient medium. We show, however, that neither intracluster light nor the radiation field of an individual nearby galaxy can cause substantial gamma-gamma absorption. Substantial gamma-gamma absorption is possible only in the case of multiple, $\\gtrsim5$, luminous nearby galaxies. This situation is not fou...

  17. Cascade quantum teleportation

    Institute of Scientific and Technical Information of China (English)

    ZHOU Nan-run; GONG Li-hua; LIU Ye

    2006-01-01

    In this letter a cascade quantum teleportation scheme is proposed. The proposed scheme needs less local quantum operations than those of quantum multi-teleportation. A quantum teleportation scheme based on entanglement swapping is presented and compared with the cascade quantum teleportation scheme. Those two schemes can effectively teleport quantum information and extend the distance of quantum communication.

  18. Intranuclear drug delivery and effective in vivo cancer therapy via estradiol-PEG-appended multiwalled carbon nanotubes.

    Science.gov (United States)

    Das, Manasmita; Singh, Raman Preet; Datir, Satyajit R; Jain, Sanyog

    2013-09-03

    Cancer cell-selective, nuclear targeting is expected to enhance the therapeutic efficacy of a myriad of antineoplastic drugs, particularly those whose pharmacodynamic site of action is the nucleus. In this study, a steroid-macromolecular bioconjugate based on PEG-linked 17β-Estradiol (E2) was appended to intrinsically cell-penetrable multiwalled carbon nanotubes (MWCNTs) for intranuclear drug delivery and effective breast cancer treatment, both in vitro and in vivo. Taking Doxorubicin (DOX) as a model anticancer agent, we tried to elucidate how E2 appendage influences the cell internalization, intracellular trafficking, and antitumor efficacy of the supramolecularly complexed drug. We observed that the combination of DOX with E2-PEG-MWCNTs not only facilitated nuclear targeting through an estrogen receptor (ER)-mediated pathway but also deciphered to a synergistic anticancer response in vivo. The antitumor efficacy of DOX@E2-PEG-MWCNTs in chemically breast cancer-induced female rats was approximately 18, 17, 5, and 2 times higher compared to the groups exposed to saline, drug-deprived E2-PEG-MWCNTs, free DOX, and DOX@m-PEG-MWCNTs, respectively. While free DOX treatment induced severe cardiotoxicity in animals, animals treated with DOX@m-PEG-MWCNTs and DOX@E2-PEG-MWCNTs were devoid of any perceivable cardiotoxicity, hepatotoxicity, and nephrotoxicity. To the best of our knowledge, this is the first instance in which cancer cell-selective, intranuclear drug delivery, and, subsequently, effective in vivo breast cancer therapy has been achieved using estrogen-appended MWCNTs as the molecular transporter.

  19. Nuclear translocation and regulation of intranuclear distribution of cytoplasmic poly(A-binding protein are distinct processes mediated by two Epstein Barr virus proteins.

    Directory of Open Access Journals (Sweden)

    Richard Park

    Full Text Available Many viruses target cytoplasmic polyA binding protein (PABPC to effect widespread inhibition of host gene expression, a process termed viral host-shutoff (vhs. During lytic replication of Epstein Barr Virus (EBV we observed that PABPC was efficiently translocated from the cytoplasm to the nucleus. Translocated PABPC was diffusely distributed but was excluded from viral replication compartments. Vhs during EBV infection is regulated by the viral alkaline nuclease, BGLF5. Transfection of BGLF5 alone into BGLF5-KO cells or uninfected 293 cells promoted translocation of PAPBC that was distributed in clumps in the nucleus. ZEBRA, a viral bZIP protein, performs essential functions in the lytic program of EBV, including activation or repression of downstream viral genes. ZEBRA is also an essential replication protein that binds to viral oriLyt and interacts with other viral replication proteins. We report that ZEBRA also functions as a regulator of vhs. ZEBRA translocated PABPC to the nucleus, controlled the intranuclear distribution of PABPC, and caused global shutoff of host gene expression. Transfection of ZEBRA alone into 293 cells caused nuclear translocation of PABPC in the majority of cells in which ZEBRA was expressed. Co-transfection of ZEBRA with BGLF5 into BGLF5-KO cells or uninfected 293 cells rescued the diffuse intranuclear pattern of PABPC seen during lytic replication. ZEBRA mutants defective for DNA-binding were capable of regulating the intranuclear distribution of PABPC, and caused PABPC to co-localize with ZEBRA. One ZEBRA mutant, Z(S186E, was deficient in translocation yet was capable of altering the intranuclear distribution of PABPC. Therefore ZEBRA-mediated nuclear translocation of PABPC and regulation of intranuclear PABPC distribution are distinct events. Using a click chemistry-based assay for new protein synthesis, we show that ZEBRA and BGLF5 each function as viral host shutoff factors.

  20. Electron-positron cascades in multiple-laser optical traps

    Science.gov (United States)

    Vranic, Marija; Grismayer, Thomas; Fonseca, Ricardo A.; Silva, Luis O.

    2017-01-01

    We present an analytical and numerical study of multiple-laser QED cascades induced with linearly polarised laser pulses. We analyse different polarisation orientations and propose a configuration that maximises cascade multiplicity and favours laser absorption. We generalise the analytical estimate for the cascade growth rate previously calculated in the field of two colliding linearly polarised laser pulses and account for multiple laser interaction. The estimate is verified by a comprehensive numerical study of four-laser QED cascades across a range of different laser intensities with QED PIC module of OSIRIS. We show that by using four linearly polarised 30 fs laser pulses, one can convert more than 50% of the total energy to gamma-rays at laser intensity I≃ {{10}24}~\\text{W}~\\text{c}{{\\text{m}}-2} . In this configuration, the laser conversion efficiency is higher compared with the case with two colliding lasers.

  1. Electron - positron cascades in multiple-laser optical traps

    CERN Document Server

    Vranic, Marija; Fonseca, Ricardo A; Silva, Luis O

    2016-01-01

    We present an analytical and numerical study of multiple-laser QED cascades induced with linearly polarised laser pulses. We analyse different polarisation orientations and propose a configuration that maximises the cascade multiplicity and favours the laser absorption. We generalise the analytical estimate for the cascade growth rate previously calculated in the field of two colliding linearly polarised laser pulses and account for multiple laser interaction. The estimate is verified by a comprehensive numerical study of four-laser QED cascades across a range of different laser intensities with QED PIC module of OSIRIS. We show that by using four linearly polarised 30 fs laser pulses, one can convert more than 50 % of the total energy to gamma-rays already at laser intensity $I\\simeq10^{24}\\ \\mathrm{W/cm^2}$. In this configuration, the laser conversion efficiency is higher compared with the case with two colliding lasers.

  2. Contribution to the study of {beta} disintegration and of nuclear structure using experiments on certain {beta}-{gamma} cascades: 198{sub Au}, 86{sub Rb}, 170{sub Tm}; Contribution a l'etude de la desintegration beta et a l'etude de la structure nucleaire a l'aide d'experiences sur certaines cascades beta-gamma: 198{sub Au}, 86{sub Rb}, 170{sub Tm}

    Energy Technology Data Exchange (ETDEWEB)

    Lachkar, J. [Commissariat a l' Energie Atomique, Bruyeres-le-Chatel (France). Centre d' Etudes; Paris-11 Univ., fabulte des Sciences 91 - Orsay (France)

    1969-07-01

    {beta}{gamma} directional angular correlations and shapes of inner beta spectra leading to the first excited level of the final nucleus enable one to determine the nuclear matrix elements typical of the {beta} transition. In the three observed first forbidden cases: {sup 170}Tm, {sup 86}Rb, {sup 198}Au, these matrix elements do not confirm the independent shell model theory. Other hypotheses are then suggested and discussed. (author) [French] Les experiences de correlation angulaire {beta}{gamma} et l'etude du spectre {beta} conduisant au premier niveau excite du noyau final permettent de determiner les elements de matrices nucleaires caracteristiques de cette transition. Dans les trois cas etudies (transitions une fois interdites): {sup 170}Tm, {sup 86}Rb, {sup 198}Au, ces elements de matrices ne peuvent etre retrouves a l'aide du modele en couches et a particules independantes. D'autres hypotheses sont alors emises et discutees. (auteur)

  3. Cascade Organic Solar Cells

    KAUST Repository

    Schlenker, Cody W.

    2011-09-27

    We demonstrate planar organic solar cells consisting of a series of complementary donor materials with cascading exciton energies, incorporated in the following structure: glass/indium-tin-oxide/donor cascade/C 60/bathocuproine/Al. Using a tetracene layer grown in a descending energy cascade on 5,6-diphenyl-tetracene and capped with 5,6,11,12-tetraphenyl- tetracene, where the accessibility of the π-system in each material is expected to influence the rate of parasitic carrier leakage and charge recombination at the donor/acceptor interface, we observe an increase in open circuit voltage (Voc) of approximately 40% (corresponding to a change of +200 mV) compared to that of a single tetracene donor. Little change is observed in other parameters such as fill factor and short circuit current density (FF = 0.50 ± 0.02 and Jsc = 2.55 ± 0.23 mA/cm2) compared to those of the control tetracene-C60 solar cells (FF = 0.54 ± 0.02 and Jsc = 2.86 ± 0.23 mA/cm2). We demonstrate that this cascade architecture is effective in reducing losses due to polaron pair recombination at donor-acceptor interfaces, while enhancing spectral coverage, resulting in a substantial increase in the power conversion efficiency for cascade organic photovoltaic cells compared to tetracene and pentacene based devices with a single donor layer. © 2011 American Chemical Society.

  4. Citoquímica de inclusões intranucleares associadas ao vírus do mosaico amarelo do salsão Cytochemical studies of the intranuclear inclusions associated with the celery yellow mosaic virus (CYMV

    Directory of Open Access Journals (Sweden)

    Neusa D. da Cruz

    1972-01-01

    Full Text Available Estudos citoquímicos, ao nível do microscópio óptico, foram efetuados para determinar a natureza química de inclusões intranucleares, de aspecto fibroso, induzidas pelo vírus do mosaico amarelo do salsão na maioria de suas hospedeiras. Os testes citoquímicos foram conduzidos em material foliar fresco ou fixado (aldeído glutárico, Carnoy 3:1 ou Bouin, tendo sido feitas as seguintes reações: hematoxilina férrica (testemunha; Sudan IV e Azul do Nilo (lipídios; iodo-iodeto (amido; Feulgen, Azur B e verde-de-metila-pironina (ácidos nucleicos; ninidrina-Schiff e "Fast Green", este último em soluções ácida e alcalina (proteínas. Os testes com verde-de-metila-pironina, Azur B e ninidrina-Schiff foram combinados com digestão enzimática pela ribonuclease ou pepsina. Os dados obtidos sugerem que, dentro da sensibilidade dos testes realizados, a inclusão contenha proteína, mas não tenha amido, lipídios ou ácidos nucleicos. Isso permite supor, portanto, que essas inclusões não sejam formadas de partículas de vírus.Cytochemical studies at optical microscopic level were made to determine the chemical nature of intranuclear inclusions with fibrous aspect which were induced by the celery yellow mosaic virus (CYMV in most of its hosts. The cytochemical tests were carried on fresh as well on fixed foliar material, fixation being in glutaric aldeid, Carnoy 3:1 or Bouin. The following reactions were tried: ferric haematoxylin (control; Sudan IV and Nile blue (for lipids; iodine ioduret (for starch; Feulgen, azur B and methyl green-pyronin (for nucleic acids; ninhydrin-Schiff and fast-green, the latter in acid and in alcaline solution (for protein. The tests with methyl green-pyronin, azur B and ninhydrin-Schiff were combined with enzimatic digestion with RNase or pepsin. The results suggest that, within the sensibility of the tests, the inclusion contains protein but does not contain starch, lipids or nucleic acids. This permit to

  5. Search for Magnetically Broadened Cascade Emission from Blazars with VERITAS

    Science.gov (United States)

    Archambault, S.; Archer, A.; Benbow, W.; Buchovecky, M.; Bugaev, V.; Cerruti, M.; Connolly, M. P.; Cui, W.; Falcone, A.; Fernández Alonso, M.; Finley, J. P.; Fleischhack, H.; Fortson, L.; Furniss, A.; Griffin, S.; Hütten, M.; Hervet, O.; Holder, J.; Humensky, T. B.; Johnson, C. A.; Kaaret, P.; Kar, P.; Kieda, D.; Krause, M.; Krennrich, F.; Lang, M. J.; Lin, T. T. Y.; Maier, G.; McArthur, S.; Moriarty, P.; Nieto, D.; O’Brien, S.; Ong, R. A.; Otte, A. N.; Pohl, M.; Popkow, A.; Pueschel, E.; Quinn, J.; Ragan, K.; Reynolds, P. T.; Richards, G. T.; Roache, E.; Rovero, A. C.; Sadeh, I.; Shahinyan, K.; Staszak, D.; Telezhinsky, I.; Tyler, J.; Wakely, S. P.; Weinstein, A.; Weisgarber, T.; Wilcox, P.; Wilhelm, A.; Williams, D. A.; Zitzer, B.

    2017-02-01

    We present a search for magnetically broadened gamma-ray emission around active galactic nuclei (AGNs), using VERITAS observations of seven hard-spectrum blazars. A cascade process occurs when multi-TeV gamma-rays from an AGN interact with extragalactic background light (EBL) photons to produce electron–positron pairs, which then interact with cosmic microwave background photons via inverse-Compton scattering to produce gamma-rays. Due to the deflection of the electron–positron pairs, a non-zero intergalactic magnetic field (IGMF) would potentially produce detectable effects on the angular distribution of the cascade emission. In particular, an angular broadening compared to the unscattered emission could occur. Through non-detection of angularly broadened emission from 1ES 1218+304, the source with the largest predicted cascade fraction, we exclude a range of IGMF strengths around 10‑14 G at the 95% confidence level. The extent of the exclusion range varies with the assumptions made about the intrinsic spectrum of 1ES 1218+304 and the EBL model used in the simulation of the cascade process. All of the sources are used to set limits on the flux due to extended emission.

  6. Production and Searches for Cascade Baryons with CLAS

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Elton

    2010-01-01

    We present the results of photoproduction cross sections of the ground state cascade $\\Xi^-$ and the first excited state $\\Xi^{*-}(1530)$ measured with the CLAS detector. The photoproduction of the cascade resonances has been investigated in the reactions $\\gamma p \\rightarrow K^+K^+(X)$ and $\\gamma p \\rightarrow K^+K^+\\pi^-(X)$. The differential and total cross sections of the $\\Xi^{-}$ were determined for photon beam energies from 2.75 to 4.75 GeV and are consistent with a production mechanism of $Y^* \\rightarrow K^+ \\Xi^-$ through a t-channel process. The cross-section of the $\\Xi^{*-}(1530)$ has been determined for photon beam energies from 3.35 to 4.75 GeV. The reaction $\\gamma p \\rightarrow K^+K^+ \\pi^- (\\Xi^0)$ has also been investigated to search for excited cascade resonances decaying to $\\pi^- \\Xi^0$. No significant signal of excited cascade states other than the well-known $\\Xi^{*-}(1530)$ is observed. We also present the latest results of a search for the $\\Phi^{--}$(1862) exotic pentaquark state in a photoproduction experiment on a deuterium target. A high-statistics sample of $\\pi^-\\Xi^-$ events have been collected and analyzed. A preliminary invariant mass spectrum of the $\\pi^-\\Xi^-$ system is presented, which is used to set upper limits on the photoproduction of the $\\Phi^{--}$ pentaquark state.

  7. Cascaded Poisson processes

    Science.gov (United States)

    Matsuo, Kuniaki; Saleh, Bahaa E. A.; Teich, Malvin Carl

    1982-12-01

    We investigate the counting statistics for stationary and nonstationary cascaded Poisson processes. A simple equation is obtained for the variance-to-mean ratio in the limit of long counting times. Explicit expressions for the forward-recurrence and inter-event-time probability density functions are also obtained. The results are expected to be of use in a number of areas of physics.

  8. Integrated Broadband Quantum Cascade Laser

    Science.gov (United States)

    Mansour, Kamjou (Inventor); Soibel, Alexander (Inventor)

    2016-01-01

    A broadband, integrated quantum cascade laser is disclosed, comprising ridge waveguide quantum cascade lasers formed by applying standard semiconductor process techniques to a monolithic structure of alternating layers of claddings and active region layers. The resulting ridge waveguide quantum cascade lasers may be individually controlled by independent voltage potentials, resulting in control of the overall spectrum of the integrated quantum cascade laser source. Other embodiments are described and claimed.

  9. Analytic Approximation of Energy Resolution in Cascaded Gaseous Detectors

    Directory of Open Access Journals (Sweden)

    Dezső Varga

    2016-01-01

    Full Text Available An approximate formula has been derived for gain fluctuations in cascaded gaseous detectors such as Gas Electron Multipliers (GEMs, based on the assumption that the charge collection, avalanche formation, and extraction steps are independent cascaded processes. In order to test the approximation experimentally, a setup involving a standard GEM layer has been constructed to measure the energy resolution for 5.9 keV gamma particles. The formula reasonably traces both the charge collection and the extraction process dependence of the energy resolution. Such analytic approximation for gain fluctuations can be applied to multi-GEM detectors where it aids the interpretation of measurements as well as simulations.

  10. Analytic approximation of energy resolution in cascaded gaseous detectors

    CERN Document Server

    Varga, Dezső

    2016-01-01

    An approximate formula has been derived for gain fluctuations in cascaded gaseous detectors such as GEM-s, based on the assumption that the charge collection, avalanche formation and extraction steps are independent cascaded processes. In order to test the approximation experimentally, a setup involving a standard GEM layer has been constructed to measure the energy resolution for 5.9 keV gamma particles. The formula reasonably traces both the charge collection as well as the extraction process dependence of the energy resolution. Such analytic approximation for gain fluctuations can be applied to multi-GEM detectors where it aids the interpretation of measurements as well as simulations.

  11. Seeded QED cascades in counter propagating laser pulses

    CERN Document Server

    Grismayer, Thomas; Martins, Joana L; Fonseca, Ricardo; Silva, Luís O

    2015-01-01

    The growth rates of seeded QED cascades in counter propagating lasers are calculated with 2D/3D QED-PIC simulations. The dependence of the growth rate on laser polarisation and intensity are compared with analytical models that support simulations results. The models provide an insight regarding the qualitative trend of the cascade growth when the intensity of the laser field is varied. The results suggest that relativistic pair plasmas and efficient conversion from laser photons to gamma rays can be created with the typical intensities planned to operate on future ultra-intense laser facilities such as ELI or VULCAN.

  12. A new cascadic multigrid

    Institute of Scientific and Technical Information of China (English)

    SHI; Zhongci

    2001-01-01

    [1]Bornemann, F., Deuflhard, P., The cascadic multigrid method for elliptic problems, Numer. Math., 996, 75: 35.[2]Bornemann, F., Deuflhard, P., The cascadic multigrid method, The Eighth International Conference on Domain Decomposition Methods for Partial Differential Equations (eds. Glowinski, R., Periaux, J., Shi, Z. et al.), New York: John Wiley and Sons, 997.[3]Bornemann, F., Krause, R., Classical and cascadic multigrid-methodogical comparison, Proceedings of the 9th International Conference on Domain Decomposition (eds. Bjorstad, P., Espedal, M., Keyes, D.), New York: John Wiley and Sons, 998.[4]Shaidurov, V., Some estimates of the rate of convergence for the cascadic conjugate gradient method, Comp. Math. Applic., 996, 3: 6.[5]Shi, Z., Xu, X., Cascadic multigrid method for the second order elliptic problem, East-West J. Numer. Math., 998, 6: 309.[6]Shi, Z., Xu, X., Cascadic multigrid for elliptic problems, East-West J. Numer. Math., 999, 7: 99.[7]Shi, Z., Xu, X., Cascadic multigrid method for the plate bending problem, East-West J. Numer. Math., 998, 6: 37.[8]Braess, D., Dahmen, W., A cascade multigrid algorithm for the Stokes equations, Number. Math., 999, 82: 79.[9]Shi, Z., Xu, X., Cascadic multigrid for parabolic problems, J. Comput. Math., 2000, 8: 450.[10]Ciarlet, P.,The Finite Element Method for Elliptic Problems, Amsterdam: North-Holland, 978.[11]Zienkiewicz, O. C., The Finite Element Method, 3rd. ed., London: McGraw-Hill, 977.[12]Powell, M. J. D., Sabin, M. A., Piecewise quadratic approximations on triangles, ACM Trans. Mat. Software, 977, 3: 36.[13]Xu, J., The auxiliary space method and optimal multigrid precondition techniques for unstructured grids, Computing, 996, 56: 25.[14]Bank, R., Dupont, T., An optimal order process for solving finite element equations, Math. Comput., 980, 36: 35.[15]Brenner, S., Convergence of nonconforming multigrid methods without full elliptic regularity, Math

  13. Atypical sporadic CJD-MM phenotype with white matter kuru plaques associated with intranuclear inclusion body and argyrophilic grain disease.

    Science.gov (United States)

    Berghoff, Anna S; Trummert, Anita; Unterberger, Ursula; Ströbel, Thomas; Hortobágyi, Tibor; Kovacs, Gabor G

    2015-08-01

    We describe an atypical neuropathological phenotype of sporadic Creutzfeldt-Jakob disease in a 76-year-old man. The clinical symptoms were characterized by progressive dementia, gait ataxia, rigidity and urinary incontinence. The disease duration was 6 weeks. MRI did not show prominent atrophy or hyperintensities in cortical areas, striatum or thalamus. Biomarker examination of the cerebrospinal fluid deviated from that seen in pure Alzheimer's disease. Triphasic waves in the EEG were detected only later in the disease course, while 14-3-3 assay was positive. PRNP genotyping revealed methionine homozygosity (MM) at codon 129. Neuropathology showed classical CJD changes corresponding to the MM type 1 cases. However, a striking feature was the presence of abundant kuru-type plaques in the white matter. This rare morphology was associated with neuropathological signs of intranuclear inclusion body disease and advanced stage of argyrophilic grain disease. These alterations did not show correlation with each other, thus seemed to develop independently. This case further highlights the complexity of neuropathological alterations in the ageing brain.

  14. Quantitative analysis of nanoscale intranuclear structural alterations in hippocampal cells in chronic alcoholism via transmission electron microscopy imaging

    Science.gov (United States)

    Sahay, Peeyush; Shukla, Pradeep K.; Ghimire, Hemendra M.; Almabadi, Huda M.; Tripathi, Vibha; Mohanty, Samarendra K.; Rao, Radhakrishna; Pradhan, Prabhakar

    2017-04-01

    Chronic alcoholism is known to alter the morphology of the hippocampus, an important region of cognitive function in the brain. Therefore, to understand the effect of chronic alcoholism on hippocampal neural cells, we employed a mouse model of chronic alcoholism and quantified intranuclear nanoscale structural alterations in these cells. Transmission electron microscopy (TEM) images of hippocampal neurons were obtained, and the degree of structural alteration in terms of mass density fluctuation was determined using the light-localization properties of optical media generated from TEM imaging. The results, which were obtained at length scales ranging from ~30 to 200 nm, show that 10–12 week-old mice fed a Lieber–DeCarli liquid (alcoholic) diet had a higher degree of structural alteration than control mice fed a normal diet without alcohol. The degree of structural alteration became significantly distinguishable at a sample length of ~100 nm, which is the typical length scale of the building blocks of cells, such as DNA, RNA, proteins and lipids. Interestingly, different degrees of structural alteration at such length scales suggest possible structural rearrangement of chromatin inside the nuclei in chronic alcoholism.

  15. Study of gamma cascades and strength functions in the neutron capture reaction {sup 77}Se(n,γ); Untersuchung von Gammakaskaden und Staerkefunktionen in der Neutroneneinfangsreaktion {sup 77}Se(n,γ)

    Energy Technology Data Exchange (ETDEWEB)

    John, Robert

    2014-07-01

    One of the most important nuclear processes is the nuclear capture reaction. The cosmic nucleosynthesis (s-process) of heavy elements produces nuclei with mass numbers greater than 56 (Iron), which cannot be produced by nuclear fusion. A nucleus gets exited to the binding energy via capture of a neutron and afterwards deexcites to the groundstate by the emission of photons (gamma rays). The characteristics of the γ rays allow conclusions about the structure of the nucleus. In this work the photons, sent out by the excited {sup 78}Se{sup *}, were analyzed. The experiment took place at the research reactor of the Institute Laue-Langevin in Grenoble, France. After a efficiency calibration and the addback procedure the multi detector setup allowed coincidence and directional correlation measurements. With the help of these measurements a level scheme was developed and the directional correlation measurements were used to assign spins to different levels. Furthermore the experimental acquired data were compared to results of a simulation (γDEX) and a photon scattering experiment carried out at the ELBE electron accelerator.

  16. Neuronal ubiquitinated intranuclear inclusions in familial and non-familial frontotemporal dementia of the motor neuron disease type associated with amyotrophic lateral sclerosis.

    Science.gov (United States)

    Bigio, Eileen H; Johnson, Nancy A; Rademaker, Alfred W; Fung, Bing B; Mesulam, M-Marsel; Siddique, Nailah; Dellefave, Lisa; Caliendo, Janice; Freeman, Stefanie; Siddique, Teepu

    2004-08-01

    Ubiquitinated cytoplasmic inclusions (Ub-CIs) in superficial frontal cortex and dentate gyrus neurons are the hallmark of frontotemporal degeneration of the motor neuron disease-type (FTD-MND-type). To date, 2 reports have described intranuclear ubiquitinated inclusions (Ub-INIs) in 9 cases of familial FTD-MND-type (without clinical or pathologic motor neuron disease, MND). In the current study we found an additional 11 cases with Ub-INIs. We have identified for the first time among these cases 2 with a negative family history and 3 that have concomitant amyotrophic lateral sclerosis (ALS). The results of the present study i) confirm a previous report of significantly lower average brain weight and longer duration in cases with Ub-INIs, ii) reveal significantly greater striatal neuronal loss and gliosis in cases with intranuclear inclusions, and iii) demonstrate that intranuclear inclusions correlate with cytoplasmic inclusions and dystrophic neurites in frontal cortex and striatum but not in dentate gyrus. In addition, the current study confirms that Ub-INIs are found in familial FTD-MND-type, but also extends the presence of Ub-INIs to familial FTD-MND (with concomitant ALS), and probably also to non-familial FTD-MND-type.

  17. Information cascade on networks

    Science.gov (United States)

    Hisakado, Masato; Mori, Shintaro

    2016-05-01

    In this paper, we discuss a voting model by considering three different kinds of networks: a random graph, the Barabási-Albert (BA) model, and a fitness model. A voting model represents the way in which public perceptions are conveyed to voters. Our voting model is constructed by using two types of voters-herders and independents-and two candidates. Independents conduct voting based on their fundamental values; on the other hand, herders base their voting on the number of previous votes. Hence, herders vote for the majority candidates and obtain information relating to previous votes from their networks. We discuss the difference between the phases on which the networks depend. Two kinds of phase transitions, an information cascade transition and a super-normal transition, were identified. The first of these is a transition between a state in which most voters make the correct choices and a state in which most of them are wrong. The second is a transition of convergence speed. The information cascade transition prevails when herder effects are stronger than the super-normal transition. In the BA and fitness models, the critical point of the information cascade transition is the same as that of the random network model. However, the critical point of the super-normal transition disappears when these two models are used. In conclusion, the influence of networks is shown to only affect the convergence speed and not the information cascade transition. We are therefore able to conclude that the influence of hubs on voters' perceptions is limited.

  18. Soft gamma rays from heavy WIMPs

    Science.gov (United States)

    Krauss, Manuel Ernst; Opferkuch, Toby; Staub, Florian; Winkler, Martin Wolfgang

    2016-12-01

    We propose an explanation of the galactic center gamma ray excess by supersymmetric WIMPs as heavy as 500 GeV. The lightest neutralino annihilates into vector-like leptons or quarks which cascade decay through intermediate Higgs bosons. Due to the long decay chains, the gamma ray spectrum is much softer than naively expected and peaks at GeV energies. The model predicts correlated diboson and dijet signatures to be tested at the LHC.

  19. Gamma Knife

    Science.gov (United States)

    ... Resources Professions Site Index A-Z Gamma Knife Gamma Knife® is a radiation therapy that uses computerized treatment planning software to help ... sparing surrounding tissue. If you're scheduled for radiation therapy using Gamma Knife®, a treatment team consisting of a radiation ...

  20. In vivo monitoring of intranuclear p27{sup kip1} protein expression in breast cancer cells during trastuzumab (Herceptin) therapy

    Energy Technology Data Exchange (ETDEWEB)

    Cornelissen, Bart [Division of Nuclear Medicine, University Health Network, Toronto, ON, Canada M5S 3E2 (Canada); Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, M5S 3M2 (Canada); MRC/CRUK Gray Institute for Radiation Oncology and Biology, Oxford University, OX3 7LJ Oxford (United Kingdom)], E-mail: bart.cornelissen@rob.ox.ac.uk; Kersemans, Veerle; McLarty, Kristin [Division of Nuclear Medicine, University Health Network, Toronto, ON, M5S 3E2 (Canada); Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, M5S 3M2 (Canada); Tran, Lara [Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, M5S 3M2 (Canada); Vallis, Katherine A. [MRC/CRUK Gray Institute for Radiation Oncology and Biology, Oxford University, OX3 7LJ Oxford (United Kingdom); Reilly, Raymond M. [Division of Nuclear Medicine, University Health Network, Toronto, ON, M5S 3E2 (Canada); Department of Medical Imaging, University of Toronto, Toronto, ON, M5S 3E2 (Canada); Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, M5S 3M2 (Canada)

    2009-10-15

    Introduction: Trastuzumab, a humanized antibody directed against the Her2 receptor, induces the expression of p27{sup kip1}, an intranuclear cyclin-dependent kinase inhibitor in some breast cancer cells. The aim of this study was to develop a radioimmunoconjugate (RIC) to monitor trastuzumab-induced p27{sup kip1} protein up-regulation in vivo. Materials and Methods: Anti-p27{sup kip1} IgG was purified, and conjugated to diethylenetriaminopentaacetate, to allow radiolabeling with {sup 111}In for in vivo detection. Then tat peptide (GRKKRRQRRRPPQGYG), containing a nuclear localization sequence (underlined), was conjugated to the Fc-domain of IgG, using NaIO{sub 4} oxidation of carbohydrates and the resulting Schiff base stabilized with NaCNBH{sub 3}. The conjugate was radiolabeled with {sup 111}In, yielding [{sup 111}In]-anti-p27{sup kip1}-tat. {sup 111}In labeling efficiency, purity and p27{sup kip1} binding were measured. Trastuzumab-induced p27{sup kip1} up-regulation was assessed in a panel of breast cancer cell lines by Western blot analysis. Uptake and retention of [{sup 111}In]-anti-p27{sup kip1}-tat were measured in MDA-MB-361 and SKBr3 cells after exposure to trastuzumab. Uptake of [{sup 111}In]-anti-p27{sup kip1}-tat was determined at 72 h postintravenous injection in MDA-MB-361 xenografts in athymic mice treated with trastuzumab or saline. Results: [{sup 111}In]-anti-p27{sup kip1}-tat was synthesized to 97% purity. The RIC was able to bind to p27{sup kip1} protein and internalized in the cells and was transported to the nuclei of MDA-MB-361 cells. The level of p27{sup kip1} protein in MDA-MB-361 cells was increased after exposure to clinically relevant doses of trastuzumab for 3 days. Trastuzumab-mediated induction of p27{sup kip1} was not associated with increased cellular uptake or nuclear localization of [{sup 111}In]-anti-p27{sup kip1}-tat (6.53{+-}0.61% vs. 6.98{+-}1.36% internalized into trastuzumab-treated vs. control cells, respectively). However

  1. Period-doubling cascades galore

    OpenAIRE

    Sander, Evelyn; Yorke, James A.

    2009-01-01

    The appearance of numerous period-doubling cascades is among the most prominent features of {\\bf parametrized maps}, that is, smooth one-parameter families of maps $F:R \\times {\\mathfrak M} \\to {\\mathfrak M}$, where ${\\mathfrak M}$ is a smooth locally compact manifold without boundary, typically $R^N$. Each cascade has infinitely many period-doubling bifurcations, and it is typical to observe -- such as in all the examples we investigate here -- that whenever there are any cascades, there are...

  2. Inferring Network Structure from Cascades

    CERN Document Server

    Ghonge, Sushrut

    2016-01-01

    Many physical, biological and social phenomena can be described by cascades taking place on a network. Often, the activity can be empirically observed, but not the underlying network of interactions. In this paper we solve the dynamics of general cascade processes. We then offer three topological inversion methods to infer the structure of any directed network given a set of cascade arrival times. Our forward and inverse formulas hold for a very general class of models where the activation probability of a node is a generic function of its degree and the number of its active neighbors. We report high success rates for synthetic and real networks, for 5 different cascade models.

  3. Pulse Summing in the gamma-Ray Spectra

    CERN Document Server

    Gromov, K Ya; Samatov, Zh K; Chumin, V G

    2004-01-01

    It was shown that the peaks formed at the summing of the cascade gamma-rays pulses can be used for the determination of gamma-ray source activity and gamma-ray registration efficency. Possible sources of the determined quantities errors have been investigated. Such a method can be useful at the nuclear reaction cross section measurements, at background analysis in looking for rare decays and so on.

  4. Energy spectrum of cascades generated by muons in Baksan underground scintillation telescope

    Science.gov (United States)

    Bakatanov, V. N.; Chudakov, A. E.; Novoseltsev, Y. F.; Novoseltseva, M. V.; Achkasov, V. M.; Semenov, A. M.; Stenkin, Y. V.

    1985-01-01

    Spectrum of cascades generated by cosmic ray muons underground is presented. The mean zenith angle of the muon arrival is theta=35 deg the depth approx. 1000 hg/sq cm. In cascades energy range 700 GeV the measured spectrum is in agreement with the sea-level integral muon spectrum index gamma=3.0. Some decrease of this exponent has been found in the range 4000 Gev.

  5. The CCFM Monte Carlo generator CASCADE Version 2.2.03

    Energy Technology Data Exchange (ETDEWEB)

    Jung, H. [DESY, Hamburg (Germany); University of Antwerp, Antwerp (Belgium); Baranov, S. [Lebedev Physics Institute, Moscow (Russian Federation); Deak, M. [University of Madrid, Instituto de Fisica Teorica UAM/CSIC, Madrid (Spain); Grebenyuk, A.; Hentschinski, M.; Knutsson, A.; Kraemer, M. [DESY, Hamburg (Germany); Hautmann, F. [University of Oxford, Oxford (United Kingdom); Kutak, K. [University of Antwerp, Antwerp (Belgium); Lipatov, A.; Zotov, N. [Moscow State University, SINP, Moscow (Russian Federation)

    2010-12-15

    Cascade is a full hadron level Monte Carlo event generator for ep, {gamma}p and p anti p and pp processes, which uses the CCFM evolution equation for the initial state cascade in a backward evolution approach supplemented with off-shell matrix elements for the hard scattering. A detailed program description is given, with emphasis on parameters the user wants to change and common block variables which completely specify the generated events. (orig.)

  6. Information cascade on networks

    CERN Document Server

    Hisakado, Masato

    2015-01-01

    In this paper, we discuss a voting model by considering three different kinds of networks: a random graph, the Barab\\'{a}si-Albert(BA) model, and a fitness model. A voting model represents the way in which public perceptions are conveyed to voters. Our voting model is constructed by using two types of voters--herders and independents--and two candidates. Independents conduct voting based on their fundamental values; on the other hand, herders base their voting on the number of previous votes. Hence, herders vote for the majority candidates and obtain information relating to previous votes from their networks. We discussed the difference between the phases on which the networks depend. Two kinds of phase transitions, an information cascade transition and a super-normal transition, were identified. The first of these is a transition between a state in which most voters make the correct choices and a state in which most of them are wrong. The second is a transition of convergence speed. The information cascade t...

  7. Energy Cascades in MHD

    Science.gov (United States)

    Alexakis, A.

    2009-04-01

    Most astrophysical and planetary systems e.g., solar convection and stellar winds, are in a turbulent state and coupled to magnetic fields. Understanding and quantifying the statistical properties of magneto-hydro-dynamic (MHD) turbulence is crucial to explain the involved physical processes. Although the phenomenological theory of hydro-dynamic (HD) turbulence has been verified up to small corrections, a similar statement cannot be made for MHD turbulence. Since the phenomenological description of Hydrodynamic turbulence by Kolmogorov in 1941 there have been many attempts to derive a similar description for turbulence in conducting fluids (i.e Magneto-Hydrodynamic turbulence). However such a description is going to be based inevitably on strong assumptions (typically borrowed from hydrodynamics) that do not however necessarily apply to the MHD case. In this talk I will discuss some of the properties and differences of the energy and helicity cascades in turbulent MHD and HD flows. The investigation is going to be based on the analysis of direct numerical simulations. The cascades in MHD turbulence appear to be a more non-local process (in scale space) than in Hydrodynamics. Some implications of these results to turbulent modeling will be discussed

  8. Linear models of activation cascades: analytical solutions and coarse-graining of delayed signal transduction.

    Science.gov (United States)

    Beguerisse-Díaz, Mariano; Desikan, Radhika; Barahona, Mauricio

    2016-08-01

    Cellular signal transduction usually involves activation cascades, the sequential activation of a series of proteins following the reception of an input signal. Here, we study the classic model of weakly activated cascades and obtain analytical solutions for a variety of inputs. We show that in the special but important case of optimal gain cascades (i.e. when the deactivation rates are identical) the downstream output of the cascade can be represented exactly as a lumped nonlinear module containing an incomplete gamma function with real parameters that depend on the rates and length of the cascade, as well as parameters of the input signal. The expressions obtained can be applied to the non-identical case when the deactivation rates are random to capture the variability in the cascade outputs. We also show that cascades can be rearranged so that blocks with similar rates can be lumped and represented through our nonlinear modules. Our results can be used both to represent cascades in computational models of differential equations and to fit data efficiently, by reducing the number of equations and parameters involved. In particular, the length of the cascade appears as a real-valued parameter and can thus be fitted in the same manner as Hill coefficients. Finally, we show how the obtained nonlinear modules can be used instead of delay differential equations to model delays in signal transduction.

  9. Development of the Gamma-Gamma Perturbed Angular Correlation One-Detector Method for the Studies of the Physicochemical Properties of Matter

    CERN Document Server

    Filossofov, D V; Korolev, N A; Egorov, V G; Lebedev, N A; Akselrod, Z Z; Brockmann, J; Rösch, F

    2001-01-01

    A new method of the perturbed angular \\gamma\\gamma-correlation (PAC) measurements was developed using one detector only. For the perturbation factor quantification the relation of the summing peak composed of two cascade \\gamma-rays of study (the perturbation-affected parameter) to the summing peak composed of one \\gamma-ray and X-ray (the perturbation non-affected parameter) was used. This method was demonstrated for the ^{111}In and ^{111m}Cd radionuclides.

  10. Cascade Distillation System Development

    Science.gov (United States)

    Callahan, Michael R.; Sargushingh, Miriam; Shull, Sarah

    2014-01-01

    NASA's Advanced Exploration Systems (AES) Life Support System (LSS) Project is chartered with de-veloping advanced life support systems that will ena-ble NASA human exploration beyond low Earth orbit (LEO). The goal of AES is to increase the affordabil-ity of long-duration life support missions, and to re-duce the risk associated with integrating and infusing new enabling technologies required to ensure mission success. Because of the robust nature of distillation systems, the AES LSS Project is pursuing develop-ment of the Cascade Distillation Subsystem (CDS) as part of its technology portfolio. Currently, the system is being developed into a flight forward Generation 2.0 design.

  11. Interband cascade lasers

    Science.gov (United States)

    Vurgaftman, I.; Weih, R.; Kamp, M.; Meyer, J. R.; Canedy, C. L.; Kim, C. S.; Kim, M.; Bewley, W. W.; Merritt, C. D.; Abell, J.; Höfling, S.

    2015-04-01

    We review the current status of interband cascade lasers (ICLs) emitting in the midwave infrared (IR). The ICL may be considered the hybrid of a conventional diode laser that generates photons via electron-hole recombination, and an intersubband-based quantum cascade laser (QCL) that stacks multiple stages for enhanced current efficiency. Following a brief historical overview, we discuss theoretical aspects of the active region and core designs, growth by molecular beam epitaxy, and the processing of broad-area, narrow-ridge, and distributed feedback (DFB) devices. We then review the experimental performance of pulsed broad area ICLs, as well as the continuous-wave (cw) characteristics of narrow ridges having good beam quality and DFBs producing output in a single spectral mode. Because the threshold drive powers are far lower than those of QCLs throughout the λ = 3-6 µm spectral band, ICLs are increasingly viewed as the laser of choice for mid-IR laser spectroscopy applications that do not require high output power but need to be hand-portable and/or battery operated. Demonstrated ICL performance characteristics to date include threshold current densities as low as 106 A cm-2 at room temperature (RT), cw threshold drive powers as low as 29 mW at RT, maximum cw operating temperatures as high as 118 °C, maximum cw output powers exceeding 400 mW at RT, maximum cw wallplug efficiencies as high as 18% at RT, maximum cw single-mode output powers as high as 55 mW at RT, and single-mode output at λ = 5.2 µm with a cw drive power of only 138 mW at RT.

  12. Unsteady turbulence cascades

    Science.gov (United States)

    Goto, Susumu; Vassilicos, J. C.

    2016-11-01

    We have run a total of 311 direct numerical simulations (DNSs) of decaying three-dimensional Navier-Stokes turbulence in a periodic box with values of the Taylor length-based Reynolds number up to about 300 and an energy spectrum with a wide wave-number range of close to -5 /3 power-law dependence at the higher Reynolds numbers. On the basis of these runs, we have found a critical time when (i) the rate of change of the square of the integral length scale turns from increasing to decreasing, (ii) the ratio of interscale energy flux to high-pass filtered turbulence dissipation changes from decreasing to very slowly increasing in the inertial range, (iii) the signature of large-scale coherent structures disappears in the energy spectrum, and (iv) the scaling of the turbulence dissipation changes from the one recently discovered in DNSs of forced unsteady turbulence and in wind tunnel experiments of turbulent wakes and grid-generated turbulence to the classical scaling proposed by G. I. Taylor [Proc. R. Soc. London, Ser. A 151, 421 (1935), 10.1098/rspa.1935.0158] and A. N. Kolmogorov [Dokl. Akad. Nauk SSSR 31, 538 (1941)]. Even though the customary theoretical basis for this Taylor-Kolmogorov scaling is a statistically stationary cascade where large-scale energy flux balances dissipation, this is not the case throughout the entire time range of integration in all our DNS runs. The recently discovered dissipation scaling can be reformulated physically as a situation in which the dissipation rates of the small and large scales evolve together. We advance two hypotheses that may form the basis of a theoretical approach to unsteady turbulence cascades in the presence of large-scale coherent structures.

  13. An automated Monte-Carlo based method for the calculation of cascade summing factors

    Science.gov (United States)

    Jackson, M. J.; Britton, R.; Davies, A. V.; McLarty, J. L.; Goodwin, M.

    2016-10-01

    A versatile method has been developed to calculate cascade summing factors for use in quantitative gamma-spectrometry analysis procedures. The proposed method is based solely on Evaluated Nuclear Structure Data File (ENSDF) nuclear data, an X-ray energy library, and accurate efficiency characterisations for single detector counting geometries. The algorithm, which accounts for γ-γ, γ-X, γ-511 and γ-e- coincidences, can be applied to any design of gamma spectrometer and can be expanded to incorporate any number of nuclides. Efficiency characterisations can be derived from measured or mathematically modelled functions, and can accommodate both point and volumetric source types. The calculated results are shown to be consistent with an industry standard gamma-spectrometry software package. Additional benefits including calculation of cascade summing factors for all gamma and X-ray emissions, not just the major emission lines, are also highlighted.

  14. Study of intranuclear collision effects in interactions of K sup + /. pi. sup + mesons with Al and Au nuclei at 250 GeV/c

    Energy Technology Data Exchange (ETDEWEB)

    Agababyan, N.M.; Gulkanyan, G.; Hakobyan, R.Sh.; Karamyan, J.K.; Megrabyan, S.S. (Erevan Inst. of Physics (Armenia)); Ajinenko, I.V.; Chliapnikov, P.V. (Institut Fiziki Vysokikh Ehnergij, Serpukhov (Russia)); Botterweck, F.; Charlet, M.; Kittel, W. (Katholieke Univ. Nijmegen (Netherlands) NIKHEF-H, Nijmegen (Netherlands)); Wolf, E.A. de; Verbeure, F. (Universitaire Instelling Antwerpen, Wilrijk (Belgium). Dept. of Physics Interuniversity Inst. for High Energies, Brussels (Belgium)); Dziunikowska, K.; Kisielewska, D.; Olkiewicz, K. (Institute of Physics and Nuclear Techniques, Cracow (Poland) Institute of Nuclear Physics, Cracow (Poland)); Endler, A.M. (Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro (Brazil)); Levchenko, B.B.; Rizatdinova, F.; Shabalina, L. (Moscow State Univ. (Russia)); Wischnewski, R. (Institut fuer Hochenergiephysik, Berlin-Zeuthen (Germany)); EHS-NA22 Collaboration

    1992-11-01

    Multiplicity, inclusive, correlation and collective characteristic of multiparticle production processes in K{sup +} Al, K{sup +} Au, {pi}{sup +} Al and {pi}{sup +} Au interactions at 250 GeV/c are studied with the European Hybrid Spectrometer, providing high statistics and almost 4{pi} acceptance for final state charged particles. It is shown that the proton energy spectrum practically does not depend on the target atomic weight, but the proton angular distributions reveal a strong A-dependence. In a model independent way, the average number of intranuclear collisions is extracted, and it is shown that their dominant part (60% for Al and 80% for Au) is caused by interactions of the non-leading particles produced in the target fragmentation. The multiplication ratio of the produced particles for the Au nucleus changes from R{approx equal}40 at the smallest rapidities in the target framentation region, down to R=0.37{+-}0.06 at the largest rapidities in the beam fragmentation region. It is found that the average total longitudinal momentum of the charged products of the beam fragmentation depends weakly on the number of leading hadron (cluster) intranuclear collisions which are characterized by a low inelasticity coefficient =0.17{+-}0.03. (orig.).

  15. OsRAN2, essential for mitosis, enhances cold tolerance in rice by promoting export of intranuclear tubulin and maintaining cell division under cold stress.

    Science.gov (United States)

    Chen, Na; Xu, Yunyuan; Wang, Xin; DU, Cheng; DU, Jizhou; Yuan, Ming; Xu, Zhihong; Chong, Kang

    2011-01-01

    With global climate change, abnormally low temperatures have affected the world's rice production. Many genes have been shown to be essential for molecular improvement of rice cold-tolerance traits. However, less is known about the molecular cellular mechanism of their response to cold stress. Here, we investigated OsRAN2 involved in regulation of cell division during cold stress in rice. Expression of OsRAN2 was increased under cold treatment, but not during salt and drought stress. The mean root mitotic index was closely related to the expression level of OsRAN2. Knockdown transgenic rice lines showed an aberrant organization of spindles during mitosis and stunted growth during development. Overexpression of OsRAN2 enhanced cold tolerance in rice. The transgenic rice overexpressing OsRAN2 showed maintained cell division, decreased proportion of cells with intranuclear tubulin and formation of a normal nuclear envelope under the cold condition. Our study suggests a mechanism for OsRAN2 in regulating cold resistance in rice by maintaining cell division through promoting the normal export of intranuclear tubulin at the end of mitosis. This insight could help improve the cold-tolerance trait in rice.

  16. Cascade Mountain Range in Oregon

    Science.gov (United States)

    Sherrod, David R.

    2016-01-01

    The Cascade mountain system extends from northern California to central British Columbia. In Oregon, it comprises the Cascade Range, which is 260 miles long and, at greatest breadth, 90 miles wide (fig. 1). Oregon’s Cascade Range covers roughly 17,000 square miles, or about 17 percent of the state, an area larger than each of the smallest nine of the fifty United States. The range is bounded on the east by U.S. Highways 97 and 197. On the west it reaches nearly to Interstate 5, forming the eastern margin of the Willamette Valley and, farther south, abutting the Coast Ranges. 

  17. Cascade Product of Permutation Groups

    OpenAIRE

    Egri-Nagy, Attila; Nehaniv, Chrystopher L.

    2013-01-01

    We define the cascade product of permutation groups as an external product, an explicit construction of substructures of the iterated wreath product that are much smaller than the full wreath product. This construction is essential for computational implementations of algebraic hierarchical decompositions of finite automata. We show how direct, semidirect, and wreath products and group extensions can all be expressed as cascade products, and analyse examples of groups that can be constructed ...

  18. Low Noise Interband Cascade Photodetectors

    Science.gov (United States)

    2012-02-28

    National Laboratories, Zhaobing Tian, Zhihua Cai, R. T. Hinkey, L. Li, Tetsuya D. Mishima , Michael B. Santos, and Matthew B. Johnson at the...Phys. 107, No. 5, 054514 (2010). 2. R. Q. Yang, Z. Tian, J. F. Klem, T. D. Mishima , M. B. Santos, and M. B. Johnson, “Interband cascade photovoltaic...2012). 4. Z. Tian, Z. Cai, R. Q. Yang, T. D. Mishima , M. B. Santos, M. B. Johnson, and J. F. Klem, “Interband Cascade Infrared Photodetectors

  19. Are longer cascades more stable?

    OpenAIRE

    2004-01-01

    Yes, they are. We consider data from experimental cascade games that were run in different laboratories, and find uniformly that subjects are more willing to follow the crowd, the bigger the crowd is �although the decision makers who are added to the crowd should in theory simply follow suit and hence reveal no information. This correlation of length and strength of cascades appears consistently across games with different parameters and different choice sets for the subjects. ...

  20. Aeroelasticity in Turbomachine-Cascades.

    Science.gov (United States)

    1982-11-10

    STABLE -180 UNSTABLE -360 ’ - ’ - -180 0. 󈧖O DIAGRAM 3 AERODYNAMIC LIFT (OENT)COEFFICIENTI AND PHASE LEADS IN DEPENDANCE OF FLOM GUANTATIES AND CASCADE...ABL -0.8 0.0 -5 0. -5 DIAGRAM ’. AERODYNAMIC NORK AND DAMPING COEFFICIENTS (FOR A RIGID NOTION) IN DEPENDANCE OF FLOW OURNTATIES AND CASCADE GEOMETRY...coefficients on blades + blade vibration + vizualization in the transonic flow domain (Schlieren) + instability dependance on flow conditions, blade

  1. Cascading Gravity is Ghost Free

    CERN Document Server

    de Rham, Claudia; Tolley, Andrew J

    2010-01-01

    We perform a full perturbative stability analysis of the 6D cascading gravity model in the presence of 3-brane tension. We demonstrate that for sufficiently large tension on the (flat) 3-brane, there are no ghosts at the perturbative level, consistent with results that had previously only been obtained in a specific 5D decoupling limit. These results establish the cascading gravity framework as a consistent infrared modification of gravity.

  2. Interband Cascade Photovoltaic Cells

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Rui Q. [Univ. of Oklahoma, Norman, OK (United States); Santos, Michael B. [Univ. of Oklahoma, Norman, OK (United States); Johnson, Matthew B. [Univ. of Oklahoma, Norman, OK (United States)

    2014-09-24

    In this project, we are performing basic and applied research to systematically investigate our newly proposed interband cascade (IC) photovoltaic (PV) cells [1]. These cells follow from the great success of infrared IC lasers [2-3] that pioneered the use of quantum-engineered IC structures. This quantum-engineered approach will enable PV cells to efficiently convert infrared radiation from the sun or other heat source, to electricity. Such cells will have important applications for more efficient use of solar energy, waste-heat recovery, and power beaming in combination with mid-infrared lasers. The objectives of our investigations are to: achieve extensive understanding of the fundamental aspects of the proposed PV structures, develop the necessary knowledge for making such IC PV cells, and demonstrate prototype working PV cells. This research will focus on IC PV structures and their segments for utilizing infrared radiation with wavelengths from 2 to 5 μm, a range well suited for emission by heat sources (1,000-2,000 K) that are widely available from combustion systems. The long-term goal of this project is to push PV technology to longer wavelengths, allowing for relatively low-temperature thermal sources. Our investigations address material quality, electrical and optical properties, and their interplay for the different regions of an IC PV structure. The tasks involve: design, modeling and optimization of IC PV structures, molecular beam epitaxial growth of PV structures and relevant segments, material characterization, prototype device fabrication and testing. At the end of this program, we expect to generate new cutting-edge knowledge in the design and understanding of quantum-engineered semiconductor structures, and demonstrate the concepts for IC PV devices with high conversion efficiencies.

  3. Communication Scheme via Cascade Chaotic Systems

    Institute of Scientific and Technical Information of China (English)

    HUA Chang-Chun; GUAN Xin-Ping

    2004-01-01

    @@ A new chaotic communication scheme is constructed. Different from the existing literature, cascade chaotic systems are employed. Two cascade modes are considered. First, we investigate the input to state cascade mode;cascade systems between different kinds of chaotic systems are considered. Then the parameter cascade case of chaotic system is studied. Under the different cases, the corresponding receivers are designed, which can succeed in recovering the former emitted signal. Simulations are performed to verify the validity of the proposed main results.

  4. Cascaded-cladding-pumped cascaded Raman fiber amplifier.

    Science.gov (United States)

    Jiang, Huawei; Zhang, Lei; Feng, Yan

    2015-06-01

    The conversion efficiency of double-clad Raman fiber laser is limited by the cladding-to-core area ratio. To get high conversion efficiency, the inner-cladding-to-core area ratio has to be less than about 8, which limits the brightness enhancement. To overcome the problem, a cascaded-cladding-pumped cascaded Raman fiber laser with multiple-clad fiber as the Raman gain medium is proposed. A theoretical model of Raman fiber amplifier with multiple-clad fiber is developed, and numerical simulation proves that the proposed scheme can improve the conversion efficiency and brightness enhancement of cladding pumped Raman fiber laser.

  5. Gamma-Gamma Angular Correlation Measurements With GRIFFIN

    Science.gov (United States)

    Maclean, Andrew; Griffin Collaboration

    2016-09-01

    The goal of this work was to explore the sensitivity of the Gamma-Ray Infrastructure For Fundamental Investigations of Nuclei (GRIFFIN) 16 clover-detector γ-ray spectrometer at TRIUMF-ISAC to such γ - γ angular correlations. The methodology was established using both experimental measurements and Geant4 simulations that were used to create angular correlation templates for the GRIFFIN geometry. Direct comparisons were made between experimental data sets and the simulated angular correlation templates. A first in-beam test of the γ - γ angular correlation measurements with GRIFFIN was performed with a radioactive beam of 66Ga. Mixing ratios of δ = - 2 . 1(2) and δ = - 0 . 08(3) were measured for the 2+ ->2+ ->0+ 833-1039 keV and 1+ ->2+ ->0+ 2752-1039 keV cascades in the daughter nucleus 66Zn. These results are in good agreement with pervious literature values and the mixing ratio for the 833-1039 keV cascade has a higher precision. Also, the sensitivity to the 1333-1039 keV cascade, with its pronounced 0+ ->2+ ->0+ angular correlation, was measured.A test measurement of the superallowed Fermi β emitter 62Ga will also be discussed. Canada Foundation of Innovation, Natural Sciences and Engineering Research Council of Canada, National Research Council of Canada and Canadian Research Chairs Program.

  6. Autoregressive cascades on random networks

    Science.gov (United States)

    Iyer, Srikanth K.; Vaze, Rahul; Narasimha, Dheeraj

    2016-04-01

    A network cascade model that captures many real-life correlated node failures in large networks via load redistribution is studied. The considered model is well suited for networks where physical quantities are transmitted, e.g., studying large scale outages in electrical power grids, gridlocks in road networks, and connectivity breakdown in communication networks, etc. For this model, a phase transition is established, i.e., existence of critical thresholds above or below which a small number of node failures lead to a global cascade of network failures or not. Theoretical bounds are obtained for the phase transition on the critical capacity parameter that determines the threshold above and below which cascade appears or disappears, respectively, that are shown to closely follow numerical simulation results.

  7. Radiative distortion of kinematic edges in cascade decays

    CERN Document Server

    Beneke, Martin; Mück, Alexander; Ubiali, Maria

    2016-01-01

    Kinematic edges of cascade decays of new particles produced in high-energy collisions may provide important constraints on the involved particles' masses. For the exemplary case of gluino decay $\\tilde{g}\\to q\\bar q \\tilde{\\chi}$ into a pair of quarks and a neutralino through a squark resonance, we study the hadronic invariant mass distribution in the vicinity of the kinematic edge. We perform a next-to-leading order calculation in the strong coupling $\\alpha_s$ and the ratio of squark width and squark mass $\\Gamma_\\tilde{q}/m_\\tilde{q}$, based on a systematic expansion in $\\Gamma_\\tilde{q}/m_\\tilde{q}$. The separation into hard, collinear and soft contributions elucidates the process dependent and universal features of distributions in the edge region, represented by on-shell decay matrix elements, universal jet functions and a soft function that depends on the resonance propagator and soft Wilson lines.

  8. Gamma watermarking

    Science.gov (United States)

    Ishikawa, Muriel Y.; Wood, Lowell L.; Lougheed, Ronald W.; Moody, Kenton J.; Wang, Tzu-Fang

    2004-05-25

    A covert, gamma-ray "signature" is used as a "watermark" for property identification. This new watermarking technology is based on a unique steganographic or "hidden writing" digital signature, implemented in tiny quantities of gamma-ray-emitting radioisotopic material combinations, generally covertly emplaced on or within an object. This digital signature may be readily recovered at distant future times, by placing a sensitive, high energy-resolution gamma-ray detecting instrument reasonably precisely over the location of the watermark, which location may be known only to the object's owner; however, the signature is concealed from all ordinary detection means because its exceedingly low level of activity is obscured by the natural radiation background (including the gamma radiation naturally emanating from the object itself, from cosmic radiation and material surroundings, from human bodies, etc.). The "watermark" is used in object-tagging for establishing object identity, history or ownership. It thus may serve as an aid to law enforcement officials in identifying stolen property and prosecuting theft thereof. Highly effective, potentially very low cost identification-on demand of items of most all types is thus made possible.

  9. Gamma watermarking

    Energy Technology Data Exchange (ETDEWEB)

    Ishikawa, Muriel Y.; Wood, Lowell L.; Lougheed, Ronald W.; Moody, Kenton J.; Wang, Tzu-Fang

    2004-05-25

    A covert, gamma-ray "signature" is used as a "watermark" for property identification. This new watermarking technology is based on a unique steganographic or "hidden writing" digital signature, implemented in tiny quantities of gamma-ray-emitting radioisotopic material combinations, generally covertly emplaced on or within an object. This digital signature may be readily recovered at distant future times, by placing a sensitive, high energy-resolution gamma-ray detecting instrument reasonably precisely over the location of the watermark, which location may be known only to the object's owner; however, the signature is concealed from all ordinary detection means because its exceedingly low level of activity is obscured by the natural radiation background (including the gamma radiation naturally emanating from the object itself, from cosmic radiation and material surroundings, from human bodies, etc.). The "watermark" is used in object-tagging for establishing object identity, history or ownership. It thus may serve as an aid to law enforcement officials in identifying stolen property and prosecuting theft thereof. Highly effective, potentially very low cost identification-on demand of items of most all types is thus made possible.

  10. Unsteady transonic flow in cascades

    Science.gov (United States)

    Surampudi, S. P.; Adamczyk, J. J.

    1984-01-01

    There is a need for methods to predict the unsteady air loads associated with flutter of turbomachinery blading at transonic speeds. The results of such an analysis in which the steady relative flow approaching a cascade of thin airfoils is assumed to be transonic, irrotational, and isentropic is presented. The blades in the cascade are allowed to undergo a small amplitude harmonic oscillation which generates a small unsteady flow superimposed on the existing steady flow. The blades are assumed to oscillate with a prescribed motion of constant amplitude and interblade phase angle. The equations of motion are obtained by linearizing about a uniform flow the inviscid nonheat conducting continuity and momentum equations. The resulting equations are solved by employing the Weiner Hopf technique. The solution yields the unsteady aerodynamic forces acting on the cascade at Mach number equal to 1. Making use of an unsteady transonic similarity law, these results are compared with the results obtained from linear unsteady subsonic and supersonic cascade theories. A parametric study is conducted to find the effects of reduced frequency, solidity, stagger angle, and position of pitching axis on the flutter.

  11. Azobenzene-functionalized cascade molecules

    DEFF Research Database (Denmark)

    Archut, A.; Vogtle, F.; De Cola, L.;

    1998-01-01

    Cascade molecules bearing up to 32 azobenzene groups in the periphery have been prepared from poly(propylene imine) dendrimers and N-hydroxysuccinimide esters. The dendritic azobenzene species show similar isomerization properties as the corresponding azobenzene monomers. The all-E azobenzene...

  12. CASCADE: Introducing AI into CBT.

    Science.gov (United States)

    Hendley, R. J.; Jurascheck, N.

    1992-01-01

    Discusses changes in training requirements of commerce and industry in the United Kingdom and describes a project, CASCADE, that was developed to investigate and implement the introduction of artificial intelligence (AI) techniques into computer-based training (CBT). An overview of pilot projects in higher education settings is provided. (eight…

  13. Applications of cascade multilevel inverters

    Institute of Scientific and Technical Information of China (English)

    彭方正; 钱照明

    2003-01-01

    Cascade multilevel inverters have been developed for electric utility applications. A cascade M-level inverter consists of (M-1)/2 H-bridges in which each bridge's dc voltage is supported by its own dc capacitor. The new inverter can: (1) generate almost sinusoidal waveform voltage while only switching one time per fundamental cycle; (2) dispense with multi-pulse inverters' transformers used in conventional utility interfaces and static var compensators; (3) enables direct parallel or series transformer-less connection to medium- and high-voltage power systems. In short, the cascade inverter is much more efficient and suitable for utility applications than traditional multi-pulse and pulse width modulation (PWM) inverters. The authors have experimentally demonstrated the superiority of the new inverter for power supply, (hybrid) electric vehicle (EV) motor drive, reactive power (var) and harmonic compensation. This paper summarizes the features, feasibility, and control schemes of the cascade inverter for utility applications including utility interface of renewable energy, voltage regulation, var compensation, and harmonic filtering in power systems. Analytical, simulated, and experimental results demonstrated the superiority of the new inverters.

  14. Applications of cascade multilevel inverters

    Institute of Scientific and Technical Information of China (English)

    彭方正; 钱照明

    2003-01-01

    Cascade multilevel inverters have been developed for electric utility applications. A cascade M-level inverter consists of (M-1)/2 H-bridges in which each bridge's dc voltage is supported by its own de ca-pacitor. The new inverter can : ( 1 ) generate almost sinusoidal waveform voltage while only switching one timeper fundamental cycle ; (2) dispense with multi-pulse inverters' transformers used in conventional utility in-terfaces and static var compensators; (3) enables direct parallel or series transformer-less connection to medium- and high-voltage power systems. In short, the cascade inverter is much more efficient and suitable for utility applications than traditional multi-pulse and pulse width modulation (PWM) inverters. The authors have experimentally demonstrated the superiority of the new inverter for power supply, (hybrid) electric vehicle (EV) motor drive, reactive power (var) and harmonic compensation. This paper summarizes the features,feasibility, and control schemes of the cascade inverter for utility applications including utility interface of renewable energy, voltage regulation, var compensation, and harmonic filtering in power systems. Analytical,simulated, and experimental results demonstrated the superiority of the new inverters.

  15. Cascade Support Vector Machines with Dimensionality Reduction

    Directory of Open Access Journals (Sweden)

    Oliver Kramer

    2015-01-01

    Full Text Available Cascade support vector machines have been introduced as extension of classic support vector machines that allow a fast training on large data sets. In this work, we combine cascade support vector machines with dimensionality reduction based preprocessing. The cascade principle allows fast learning based on the division of the training set into subsets and the union of cascade learning results based on support vectors in each cascade level. The combination with dimensionality reduction as preprocessing results in a significant speedup, often without loss of classifier accuracies, while considering the high-dimensional pendants of the low-dimensional support vectors in each new cascade level. We analyze and compare various instantiations of dimensionality reduction preprocessing and cascade SVMs with principal component analysis, locally linear embedding, and isometric mapping. The experimental analysis on various artificial and real-world benchmark problems includes various cascade specific parameters like intermediate training set sizes and dimensionalities.

  16. Probing Intergalactic Magnetic Fields with Simulations of Electromagnetic Cascades

    CERN Document Server

    Batista, Rafael Alves; Sigl, Guenter; Vachaspati, Tanmay

    2016-01-01

    We determine the effect of intergalactic magnetic fields on the distribution of high energy gamma rays by performing three-dimensional Monte Carlo simulations of the development of gamma-ray-induced electromagnetic cascades in the magnetized intergalactic medium. We employ the so-called 'Large Sphere Observer' method to efficiently simulate blazar gamma ray halos. We study magnetic fields with a Batchelor spectrum and with maximal left- and right-handed helicities. We also consider the case of sources whose jets are tilted with respect to the line of sight. We verify the formation of extended gamma ray halos around the source direction, and observe spiral-like patterns if the magnetic field is helical. We apply the $Q$-statistics to the simulated halos to extract their spiral nature and also propose an alternative method, the $S$-statistics. Both methods provide a quantative way to infer the helicity of the intervening magnetic fields from the morphology of individual blazar halos for magnetic field strengths...

  17. Cascaded Bragg scattering in fiber optics.

    Science.gov (United States)

    Xu, Y Q; Erkintalo, M; Genty, G; Murdoch, S G

    2013-01-15

    We report on a theoretical and experimental study of cascaded Bragg scattering in fiber optics. We show that the usual energy-momentum conservation of Bragg scattering can be considerably relaxed via cascade-induced phase-matching. Experimentally we demonstrate frequency translation over six- and 11-fold cascades, in excellent agreement with derived phase-matching conditions.

  18. (n,{gamma}) Experiments on tin isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Baramsai, B.; Mitchell, G. E.; Walker, C. L.; Rusev, G. [North Carolina State University, Raleigh, NC 27695, USA and Triangle Universities Nuclear Laboratory, Durham, NC 27708 (United States); Bredeweg, T. A.; Couture, A.; Haight, R. C.; Jandel, M.; Mosby, S.; O' Donnell, J. M.; Rundberg, R. S.; Ullmann, J. L.; Vieira, D. J. [Los Alamos National Laboratory, P.O. Box 1663, Los Alamos, NM 87545 (United States); Becvar, F.; Krticka, M.; Kroll, J. [Charles University of Prague, V Holesovickach 2, 180 00 Prague 8 (Czech Republic); Agvaanluvsan, U.; Dashdorj, D.; Erdenehuluun, B.; Tsend-Ayush, T. [MonAme Scientific Research Center, Ulaanbaatar (Mongolia)

    2013-04-19

    Neutron capture experiments on highly enriched {sup 117,119}Sn isotopes were performed with the DANCE detector array located at the Los Alamos Neutron Science Center. The DANCE detector provides detailed information about the multi-step {gamma}-ray cascade following neutron capture. Analysis of the experimental data provides important information to improve understanding of the neutron capture reaction, including a test of the statistical model, the assignment of spins and parities of neutron resonances, and information concerning the Photon Strength Function (PSF) and Level Density (LD) below the neutron separation energy. Preliminary results for the (n,{gamma}) reaction on {sup 117,119}Sn are presented. Resonance spins of the odd-A tin isotopes were almost completely unknown. Resonance spins and parities have been assigned via analysis of the multi-step {gamma}-ray spectra and directional correlations.

  19. Bankruptcy Cascades in Interbank Markets

    Science.gov (United States)

    Tedeschi, Gabriele; Mazloumian, Amin; Gallegati, Mauro; Helbing, Dirk

    2012-01-01

    We study a credit network and, in particular, an interbank system with an agent-based model. To understand the relationship between business cycles and cascades of bankruptcies, we model a three-sector economy with goods, credit and interbank market. In the interbank market, the participating banks share the risk of bad debits, which may potentially spread a bank’s liquidity problems through the network of banks. Our agent-based model sheds light on the correlation between bankruptcy cascades and the endogenous economic cycle of booms and recessions. It also demonstrates the serious trade-off between, on the one hand, reducing risks of individual banks by sharing them and, on the other hand, creating systemic risks through credit-related interlinkages of banks. As a result of our study, the dynamics underlying the meltdown of financial markets in 2008 becomes much better understandable. PMID:23300760

  20. Thermal cascaded lattice Boltzmann method

    CERN Document Server

    Fei, Linlin

    2016-01-01

    In this paper, a thermal cascaded lattice Boltzmann method (TCLBM) is developed in combination with the double-distribution-function (DDF) approach. A density distribution function relaxed by the cascaded scheme is employed to solve the flow field, and a total energy distribution function relaxed by the BGK scheme is used to solve temperature field, where two distribution functions are coupled naturally. The forcing terms are incorporated by means of central moments, which is consistent with the previous force scheme [Premnath \\emph{et al.}, Phys. Rev. E \\textbf{80}, 036702 (2009)] but the derivation is more intelligible and the evolution process is simpler. In the method, the viscous heat dissipation and compression work are taken into account, the Prandtl number and specific-heat ratio are adjustable, the external force is considered directly without the Boussinesq assumption, and the low-Mach number compressible flows can also be simulated. The forcing scheme is tested by simulating a steady Taylor-Green f...

  1. Cascade Chaotic System With Applications.

    Science.gov (United States)

    Zhou, Yicong; Hua, Zhongyun; Pun, Chi-Man; Chen, C L Philip

    2015-09-01

    Chaotic maps are widely used in different applications. Motivated by the cascade structure in electronic circuits, this paper introduces a general chaotic framework called the cascade chaotic system (CCS). Using two 1-D chaotic maps as seed maps, CCS is able to generate a huge number of new chaotic maps. Examples and evaluations show the CCS's robustness. Compared with corresponding seed maps, newly generated chaotic maps are more unpredictable and have better chaotic performance, more parameters, and complex chaotic properties. To investigate applications of CCS, we introduce a pseudo-random number generator (PRNG) and a data encryption system using a chaotic map generated by CCS. Simulation and analysis demonstrate that the proposed PRNG has high quality of randomness and that the data encryption system is able to protect different types of data with a high-security level.

  2. Optimally Training a Cascade Classifier

    CERN Document Server

    Shen, Chunhua; Hengel, Anton van den

    2010-01-01

    Cascade classifiers are widely used in real-time object detection. Different from conventional classifiers that are designed for a low overall classification error rate, a classifier in each node of the cascade is required to achieve an extremely high detection rate and moderate false positive rate. Although there are a few reported methods addressing this requirement in the context of object detection, there is no a principled feature selection method that explicitly takes into account this asymmetric node learning objective. We provide such an algorithm here. We show a special case of the biased minimax probability machine has the same formulation as the linear asymmetric classifier (LAC) of \\cite{wu2005linear}. We then design a new boosting algorithm that directly optimizes the cost function of LAC. The resulting totally-corrective boosting algorithm is implemented by the column generation technique in convex optimization. Experimental results on object detection verify the effectiveness of the proposed bo...

  3. Bankruptcy cascades in interbank markets.

    Directory of Open Access Journals (Sweden)

    Gabriele Tedeschi

    Full Text Available We study a credit network and, in particular, an interbank system with an agent-based model. To understand the relationship between business cycles and cascades of bankruptcies, we model a three-sector economy with goods, credit and interbank market. In the interbank market, the participating banks share the risk of bad debits, which may potentially spread a bank's liquidity problems through the network of banks. Our agent-based model sheds light on the correlation between bankruptcy cascades and the endogenous economic cycle of booms and recessions. It also demonstrates the serious trade-off between, on the one hand, reducing risks of individual banks by sharing them and, on the other hand, creating systemic risks through credit-related interlinkages of banks. As a result of our study, the dynamics underlying the meltdown of financial markets in 2008 becomes much better understandable.

  4. Lens Coupled Quantum Cascade Laser

    Science.gov (United States)

    Hu, Qing (Inventor); Lee, Alan Wei Min (Inventor)

    2013-01-01

    Terahertz quantum cascade (QC) devices are disclosed that can operate, e.g., in a range of about 1 THz to about 10 THz. In some embodiments, QC lasers are disclosed in which an optical element (e.g., a lens) is coupled to an output facet of the laser's active region to enhance coupling of the lasing radiation from the active region to an external environment. In other embodiments, terahertz amplifier and tunable terahertz QC lasers are disclosed.

  5. Control of Cascaded Multilevel Inverters

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Abstract-A new type of multilevel inverter is introduced which is created by cascading two three-phase three-level inverters using the load connection, but requires only one DC voltage source. This new inverter can operateas a seven-level inverter and naturally splits the power conversion into a higher-voltage lower-frequency inverter and a lower-voltage higher-fre-quency inverter. This type of system presents particular advantages to Naval ship propulsion systems which rely on high power quality, survivable drives. New control methods are described involving both joint and separate control of the individual three-level inverters. Simulation resuits demonstrate the effectiveness of both controls. A laboratory set-up at the Naval Surface Warfare Center power electronics laboratory was used to validate the proposed joint-inverter control. Due to the effect of compounding levels in the cascaded inverter, a high number of levels are available resulting in a voltage THD of 9% (without filtering). Index Terms-Cascaded inverter, multilevel inverter, three-level inverter.

  6. Turbulence: does energy cascade exist?

    CERN Document Server

    Josserand, Christophe; Lehner, Thierry; Pomeau, Yves

    2016-01-01

    To answer the question whether a cascade of energy exists or not in turbulence, we propose a set of correlation functions able to test if there is an irreversible transfert of energy, step by step, from large to small structures. These tests are applied to real Eulerian data of a turbulent velocity flow, taken in the wind grid tunnel of Modane, and also to a prototype model equation for wave turbulence. First we demonstrate the irreversible character of the flow by using multi-time correlation function at a given point of space. Moreover the unexpected behavior of the test function leads us to connect irreversibility and finite time singularities (intermittency). Secondly we show that turbulent cascade exists, and is a dynamical process, by using a test function depending on time and frequency. The cascade shows up only in the inertial domain where the kinetic energy is transferred more rapidly (on average) from the wavenumber $k_{1}$ to $k_{2}$ than from $k_{1}$ to $k'_{2}$ larger than $k_{2}$.

  7. Electron-$\\gamma$ PAC new possibilities for NQI studies

    CERN Document Server

    Correia, J G; Marques, J G; Ramos, A R; Melo, A A; Soares, J C

    2000-01-01

    The application of hyperfine interaction techniques to problems in solid state physics has been steadily growing over the last decade with the use of radioactive ion beam facilities such as ISOLDE at CERN. New applications of the e$^-\\!-\\gamma$ perturbed angular correlation (PAC) technique are underway at ISOLDE using probe nuclei with highly converted cascades. In this paper we present the motivation for extending PAC experiments to elements/isotopes not usable with the conventional $\\gamma-\\gamma$ PAC technique. Examples will be shown where the long-lived $^{73}$As/ $^{73}$Ge, the short lived $^{127}$Ba/$^{127}$Cs and the $^{197m}$Hg/$^{197}$Hg decay cascades are applied to measurements of nuclear quadrupole interactions in materials. (37 refs).

  8. Possible distance indicators in gamma-ray pulsars

    Institute of Scientific and Technical Information of China (English)

    Wei Wang

    2011-01-01

    Distance measurement of gamma-ray pulsars is a current challenge in pulsar studies. The Large Area Telescope (LAT) aboard the Fermi gamma-ray observatory discovered more than 70 gamma-ray pulsars including 24 new gamma-selected pulsars with almost no distance information. We study the relation between gammaray emission efficiency (η = Lγ/E) and pulsar parameters for young radio-selected gamma-ray pulsars with known distance information in the first gamma-ray pulsar catalog reported by Fermi/LAT. We have introduced three generation-order parameters to describe the gamma-ray emission properties of pulsars, and find a strong correlation of rη- ζ3, a generation-order parameter which reflects γ-ray photon generation in the pair cascade processes induced by magnetic field absorption in a pulsar's magnetosphere.A good correlation of η- BLC, the magnetic field at the light cylinder radius, is also found. These correlations are the distance indicators in gamma-ray pulsars used to evaluate distances for gamma-selected pulsars. Distances of 25 gamma-selected pulsars are estimated, which could be tested by other distance measurement methods. The physical origin of the correlations may also be interesting for pulsar studies.

  9. On the possibility of sub-TeV Gamma-ray emission from Cyg X-3

    CERN Document Server

    Bednarek, W

    2010-01-01

    The compact X-ray binary system Cyg X-3 has been recently discovered as a source of GeV gamma-rays by the AGILE and the {\\it Fermi} satellites. It shows emission features in the GeV gamma-rays similar to other gamma-ray binaries which were also observed in the TeV gamma-rays (LS 5039 and LSI +61 303). The question appears whether Cyg X-3 can be also detected in the TeV gamma-rays by the Cherenkov telescopes. Here we discuss this problem in detail based on the anisotropic inverse Compton (IC) e-p pair cascade model successfully applied to TeV gamma-ray binaries. We calculate the gamma-ray light curves and gamma-ray spectra expected from the cascade process occurring inside the Cyg X-3 binary system. It is found that the gamma-ray light curves at GeV energies can be consistent with the gamma-ray light curve observed by the Fermi for reasonable parameters of the orbit of the injection source of relativistic electrons. Moreover, we show that in such a model the sub-TeV gamma-ray emission (above 100 GeV) is expect...

  10. Energy cascades in the upper ocean

    Institute of Scientific and Technical Information of China (English)

    Ray Q.Lin; Scott Chubb

    2006-01-01

    Wave-wave interactions cause energy cascades. These are the most important processes in the upper ocean because they govern wave-growth and dissipation. Through indirect cascades, wave energy is transferred from higher frequencies to lower frequencies, leading to wave growth. In direct cascades, energy is transferred from lower frequencies to the higher frequencies, which causes waves to break, and dissipation of wave energy. However, the evolution and origin of energy cascade processes are still not fully understood. In particular, for example, results from a recent theory (Kalmykov, 1998) suggest that the class I wave-wave interactions (defined by situations involving 4-, 6-, 8-, etc, even numbers of resonantly interacting waves) cause indirect cascades, and Class II wave-wave interactions (involving, 5-, 7-, 9-, etc, .., odd numbers of waves) cause direct cascades. In contrast to this theory, our model results indicate the 4-wave interactions can cause significant transfer of wave energy through both direct and indirect cascades. In most situations, 4-wave interactions provide the major source of energy transfer for both direct cascades and indirect cascades, except when the wave steepness is larger than 0.28. Our model results agree well with wave measurements, obtained using field buoy data (for example, Lin and Lin, 2002). In particular, in these observations, asymmetrical wave-wave interactions were studied. They found that direct and indirect cascades both are mainly due to the 4-wave interactions when wave steepness is less than 0.3.

  11. Gamma-ray astronomy: From Fermi up to the HAWC high-energy {gamma}-ray observatory in Sierra Negra

    Energy Technology Data Exchange (ETDEWEB)

    Carraminana, Alberto [Instituto Nacional de Astrofisica, Optica y Electronica Luis Enrique Erro 1, Tonantzintla, Puebla 72840 (Mexico); Collaboration: HAWC Collaboration

    2013-06-12

    Gamma-rays represent the most energetic electromagnetic window for the study of the Universe. They are studied both from space at MeV and GeV energies, with instruments like the Fermi{gamma}-ray Space Telescope, and at TeV energies with ground based instruments profiting of particle cascades in the atmosphere and of the Cerenkov radiation of charged particles in the air or in water. The Milagro gamma-ray observatory represented the first instrument to successfully implement the water Cerenkov technique for {gamma}-ray astronomy, opening the ground for the more sensitive HAWC {gamma}-ray observatory, currently under development in the Sierra Negra site and already providing early science results.

  12. Cascade photons as test of protons in UHECR

    CERN Document Server

    Berezinsky, V; Kalashev, O

    2016-01-01

    An isotropic component of high energy $\\gamma$-ray spectrum measured by Fermi LAT constrains the proton component of UHECR. The strongest restriction comes from the highest, $(580-820)$ GeV, energy bin. One more constraint on the proton component is provided by the IceCube upper bound on ultrahigh energy cosmogenic neutrino flux. We study the influence of these restrictions on the source properties, such as evolution and distribution of sources, their energy spectrum and admixture of nuclei. We also study the sensitivity of restrictions to various Fermi LAT galactic foreground models (model B being less restrictive), to the choice of extragalactic background light model and to overall normalization of the energy spectrum. We claim that the $\\gamma$-ray-cascade constraints are stronger than the neutrino ones, and that however many proton models are viable. The basic parameters of such models are relatively large $\\gamma_g$ and not very large $z_{\\max}$. The allowance for H$e^4$ admixture also relaxes the restr...

  13. Visible cascade Higgs decays to four photons at hadron colliders.

    Science.gov (United States)

    Chang, Spencer; Fox, Patrick J; Weiner, Neal

    2007-03-16

    The presence of a new singlet scalar particle a can open up new decay channels for the Higgs boson, through cascades of the form h --> 2a --> X, possibly making discovery through standard model channels impossible. If a is CP odd, its decays are particularly sensitive to new physics. Quantum effects from heavy fields can naturally make h --> 4 g the dominant decay which is difficult to observe at hadron colliders, and is allowed by CERN LEP for m(h) > 82 GeV. However, there are usually associated decays, either h --> 2g2gamma or h --> 4gamma, which are more promising. The decay h-->4gamma is a clean channel that can discover both a and h. At the CERN LHC with 300 fb(-1) of luminosity, a branching ratio of order 10(-4) is sufficient for discovery for a large range of Higgs boson masses. With total luminosity of approximately 8 fb(-1), discovery at the Fermilab Tevatron requires more than 5 x 10(-3) in branching ratio.

  14. gamma-gamma Interactions from Real to Virtual Photons

    CERN Document Server

    Sjöstrand, Torbjörn

    2000-01-01

    A `complete' framework for gamma-gamma / gamma*-gamma / gamma*-gamma* interactions is presented. The emphasis is on providing a model for gamma-gamma physics at all photon virtualities, including the difficult transition region around the rho meson mass.

  15. A Comparison of Methods for Cascade Prediction

    CERN Document Server

    Guo, Ruocheng

    2016-01-01

    Information cascades exist in a wide variety of platforms on Internet. A very important real-world problem is to identify which information cascades can go viral. A system addressing this problem can be used in a variety of applications including public health, marketing and counter-terrorism. As a cascade can be considered as compound of the social network and the time series. However, in related literature where methods for solving the cascade prediction problem were proposed, the experimental settings were often limited to only a single metric for a specific problem formulation. Moreover, little attention was paid to the run time of those methods. In this paper, we first formulate the cascade prediction problem as both classification and regression. Then we compare three categories of cascade prediction methods: centrality based, feature based and point process based. We carry out the comparison through evaluation of the methods by both accuracy metrics and run time. The results show that feature based met...

  16. Spray formation: an inverse cascade

    CERN Document Server

    Ling, Yue; Tryggvason, Gretar; zaleski, Stephane

    2015-01-01

    We present a study of droplet formation in a gas-liquid mixing layer using direct numerical simulation. It is seen that two mechanisms compete to generate the droplets: fingering at the tip of the waves and hole formation in the thin liquid sheet. The three dimensional liquid structures are much shorter than the longitudinal wavelength of the instability at the first instant of their formation. As time evolves, the structures evolves to larger and larger scales, in a way similar to the inverse cascade of length scales in droplet impact and impact crown formation.

  17. Disaster Mythology and Availability Cascades

    Directory of Open Access Journals (Sweden)

    Lisa Grow Sun

    2013-04-01

    Full Text Available Sociological research conducted in the aftermath of natural disasters has uncovered a number of “disaster myths” – widely shared misconceptions about typical post-disaster human behavior. This paper discusses the possibility that perpetuation of disaster mythology reflects an “availability cascade,” defined in prior scholarship as a “self-reinforcing process of collective belief formation by which an expressed perception triggers a chain reaction that gives the perception increasing plausibility through its rising availability in public discourse.” (Kuran and Sunstein 1999. Framing the spread of disaster mythology as an availability cascade suggests that certain tools may be useful in halting the myths’ continued perpetuation. These tools include changing the legal and social incentives of so-called “availability entrepreneurs” – those principally responsible for beginning and perpetuating the cascade, as well as insulating decision-makers from political pressures generated by the availability cascade. This paper evaluates the potential effectiveness of these and other solutions for countering disaster mythology. Las investigaciones sociológicas realizadas tras los desastres naturales han hecho evidentes una serie de “mitos del desastre”, conceptos erróneos ampliamente compartidos sobre el comportamiento humano típico tras un desastre. Este artículo analiza la posibilidad de que la perpetuación de los mitos del desastre refleje una “cascada de disponibilidad”, definida en estudios anteriores como un “proceso de auto-refuerzo de la formación de una creencia colectiva, a través del que una percepción expresada produce una reacción en cadena que hace que la percepción sea cada vez más verosímil, a través de una mayor presencia en el discurso público” (Kuran y Sunstein 1999. Enmarcar la propagación de los mitos del desastre como una cascada de disponibilidad sugiere que ciertas herramientas pueden ser

  18. Cascades on clique-based graphs

    CERN Document Server

    Hackett, Adam

    2013-01-01

    We present an analytical approach to determining the expected cascade size in a broad range of dynamical models on the class of highly-clustered random graphs introduced in [J. P. Gleeson, Phys. Rev. E 80, 036107 (2009)]. A condition for the existence of global cascades is also derived. Applications of this approach include analyses of percolation, and Watts's model. We show how our techniques can be used to study the effects of in-group bias in cascades on social networks.

  19. Lateral Modes in Quantum Cascade Lasers

    Directory of Open Access Journals (Sweden)

    Gregory C. Dente

    2016-03-01

    Full Text Available We will examine the waveguide mode losses in ridge-guided quantum cascade lasers. Our analysis illustrates how the low-loss mode for broad-ridge quantum cascade lasers (QCLs can be a higher-order lateral waveguide mode that maximizes the feedback from the sloped ridge-wall regions. The results are in excellent agreement with the near- and far-field data taken on broad-ridge-guided quantum cascade lasers processed with sloped ridge walls.

  20. GAMMA-400 gamma-ray observatory

    CERN Document Server

    Topchiev, N P; Bonvicini, V; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bakaldin, A V; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, L; Bongi, M; Bottai, S; Castellini, G; Cattaneo, P W; Cumani, P; Dalkarov, O D; Dedenko, G L; De Donato, C; Dogiel, V A; Finetti, N; Gascon, D; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Leonov, A A; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Martinez, M; Menshenin, A L; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Paredes, J M; Pearce, M; Picozza, P; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Serdin, O V; Sparvoli, R; Spillantini, P; Stozhkov, Yu I; Suchkov, S I; Taraskin, A A; Tavani, M; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Ward, J E; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2015-01-01

    The GAMMA-400 gamma-ray telescope with excellent angular and energy resolutions is designed to search for signatures of dark matter in the fluxes of gamma-ray emission and electrons + positrons. Precision investigations of gamma-ray emission from Galactic Center, Crab, Vela, Cygnus, Geminga, and other regions will be performed, as well as diffuse gamma-ray emission, along with measurements of high-energy electron + positron and nuclei fluxes. Furthermore, it will study gamma-ray bursts and gamma-ray emission from the Sun during periods of solar activity. The energy range of GAMMA-400 is expected to be from ~20 MeV up to TeV energies for gamma rays, up to 20 TeV for electrons + positrons, and up to 10E15 eV for cosmic-ray nuclei. For high-energy gamma rays with energy from 10 to 100 GeV, the GAMMA-400 angular resolution improves from 0.1{\\deg} to ~0.01{\\deg} and energy resolution from 3% to ~1%; the proton rejection factor is ~5x10E5. GAMMA-400 will be installed onboard the Russian space observatory.

  1. WHISTLER TURBULENCE FORWARD CASCADE VERSUS INVERSE CASCADE: THREE-DIMENSIONAL PARTICLE-IN-CELL SIMULATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Ouliang [Oracle Corporation, Redwood Shores, CA (United States); Gary, S. Peter [Space Science Institute, Boulder, CO (United States); Wang, Joseph, E-mail: ouliang@usc.edu, E-mail: pgary@lanl.gov, E-mail: josephjw@usc.edu [University of Southern California, Los Angeles, CA (United States)

    2015-02-20

    We present the results of the first fully three-dimensional particle-in-cell simulations of decaying whistler turbulence in a magnetized, homogeneous, collisionless plasma in which both forward cascades to shorter wavelengths, and inverse cascades to longer wavelengths are allowed to proceed. For the electron beta β {sub e} = 0.10 initial value considered here, the early-time rate of inverse cascade is very much smaller than the rate of forward cascade, so that at late times the fluctuation energy in the regime of the inverse cascade is much weaker than that in the forward cascade regime. Similarly, the wavevector anisotropy in the inverse cascade regime is much weaker than that in the forward cascade regime.

  2. Unsteady transonic flow over cascade blades

    Science.gov (United States)

    Surampudi, S. P.; Adamczyk, J. J.

    1986-01-01

    An attempt is made to develop an efficient staggered cascade blade unsteady aerodynamics model for the neighborhood of March 1, representing the blade row by a rectilinear two-dimensional cascade of thin, flat plate airfoils. The equations of motion are derived on the basis of linearized transonic small perturbation theory, and an analytical solution is obtained by means of the Wiener-Hopf procedure. Making use of the transonic similarity law, the results obtained are compared with those of other linearized cascade analyses. A parametric study is conducted to find the effects of reduced frequency, stagger angle, solidity, and the location of the pitching axis on cascade stability.

  3. Contingency Analysis of Cascading Line Outage Events

    Energy Technology Data Exchange (ETDEWEB)

    Thomas L Baldwin; Magdy S Tawfik; Miles McQueen

    2011-03-01

    As the US power systems continue to increase in size and complexity, including the growth of smart grids, larger blackouts due to cascading outages become more likely. Grid congestion is often associated with a cascading collapse leading to a major blackout. Such a collapse is characterized by a self-sustaining sequence of line outages followed by a topology breakup of the network. This paper addresses the implementation and testing of a process for N-k contingency analysis and sequential cascading outage simulation in order to identify potential cascading modes. A modeling approach described in this paper offers a unique capability to identify initiating events that may lead to cascading outages. It predicts the development of cascading events by identifying and visualizing potential cascading tiers. The proposed approach was implemented using a 328-bus simplified SERC power system network. The results of the study indicate that initiating events and possible cascading chains may be identified, ranked and visualized. This approach may be used to improve the reliability of a transmission grid and reduce its vulnerability to cascading outages.

  4. Single-Seed Cascades on Clustered Networks

    CERN Document Server

    McSweeney, John K

    2015-01-01

    We consider a dynamic network cascade process developed by Watts applied to a random networks with a specified amount of clustering, belonging to a class of random networks developed by Newman. We adapt existing tree-based methods to formulate an appropriate two-type branching process to describe the spread of a cascade started with a single active node, and obtain a fixed-point equation to implicitly express the extinction probability of such a cascade. In so doing, we also recover a special case of a formula of Hackett et al. giving conditions for certain extinction of the cascade.

  5. Multifunctional Cascaded Metamaterials: Integrated Transmitarrays

    Science.gov (United States)

    Elsakka, Amr A.; Asadchy, Viktar S.; Faniayeu, Ihar A.; Tcvetkova, Svetlana N.; Tretyakov, Sergei A.

    2016-10-01

    Control of electromagnetic waves using engineered materials is very important in a wide range of applications, therefore there is always a continuous need for new and more efficient solutions. Known natural and artificial materials and surfaces provide a particular functionality in the frequency range they operate but cast a "shadow" and produce reflections at other frequencies. Here, we introduce a concept of multifunctional engineered materials that possess different predetermined functionalities at different frequencies. Such response can be accomplished by cascading metasurfaces (thin composite layers) that are designed to perform a single operation at the desired frequency and are transparent elsewhere. Previously, out-of-band transparent metasurfaces for control over reflection and absorption were proposed. In this paper, to complete the full set of functionalities for wave control, we synthesize transmitarrays that tailor transmission in a desired way, being "invisible" beyond the operational band. The designed transmitarrays for wavefront shaping and anomalous refraction are tested numerically and experimentally. To demonstrate our concept of multifunctional engineered materials, we have designed a cascade of three metasurfaces that performs three different functions for waves at different frequencies. Remarkably, applied to volumetric metamaterials, our concept can enable a single composite possessing desired multifunctional response.

  6. A honey bee hexamerin, HEX 70a, is likely to play an intranuclear role in developing and mature ovarioles and testioles.

    Directory of Open Access Journals (Sweden)

    Juliana R Martins

    Full Text Available Insect hexamerins have long been known as storage proteins that are massively synthesized by the larval fat body and secreted into hemolymph. Following the larval-to-pupal molt, hexamerins are sequestered by the fat body via receptor-mediated endocytosis, broken up, and used as amino acid resources for metamorphosis. In the honey bee, the transcript and protein subunit of a hexamerin, HEX 70a, were also detected in ovaries and testes. Aiming to identify the subcellular localization of HEX 70a in the female and male gonads, we used a specific antibody in whole mount preparations of ovaries and testes for analysis by confocal laser-scanning microscopy. Intranuclear HEX 70a foci were evidenced in germ and somatic cells of ovarioles and testioles of pharate-adult workers and drones, suggesting a regulatory or structural role. Following injection of the thymidine analog EdU we observed co-labeling with HEX 70a in ovariole cell nuclei, inferring possible HEX 70a involvement in cell proliferation. Further support to this hypothesis came from an injection of anti-HEX 70a into newly ecdysed queen pupae where it had a negative effect on ovariole thickening. HEX 70a foci were also detected in ovarioles of egg laying queens, particularly in the nuclei of the highly polyploid nurse cells and in proliferating follicle cells. Additional roles for this storage protein are indicated by the detection of nuclear HEX 70a foci in post-meiotic spermatids and spermatozoa. Taken together, these results imply undescribed roles for HEX 70a in the developing gonads of the honey bee and raise the possibility that other hexamerins may also have tissue specific functions.

  7. Transcutaneous vagus nerve stimulation (tVNS) enhances response selection during action cascading processes.

    Science.gov (United States)

    Steenbergen, Laura; Sellaro, Roberta; Stock, Ann-Kathrin; Verkuil, Bart; Beste, Christian; Colzato, Lorenza S

    2015-06-01

    The ever-changing environment we are living in requires us to apply different action control strategies in order to fulfill a task goal. Indeed, when confronted with multiple response options it is fundamental to prioritize and cascade different actions. So far, very little is known about the neuromodulation of action cascading. In this study we assessed the causal role of the gamma-aminobutyric acid (GABA)-ergic and noradrenergic system in modulating the efficiency of action cascading by applying transcutaneous vagus nerve stimulation (tVNS), a new non-invasive and safe method to stimulate the vagus nerve and to increase GABA and norepinephrine concentrations in the brain. A single-blind, sham-controlled, between-group design was used to assess the effect of on-line (i.e., stimulation overlapping with the critical task) tVNS in healthy young volunteers (n=30)-on a stop-change paradigm. Results showed that active, as compared to sham stimulation, enhanced response selection functions during action cascading and led to faster responses when two actions were executed in succession. These findings provide evidence for the important role of the GABA-ergic and noradrenergic system in modulating performance in action cascading.

  8. Probing the Intergalactic Magnetic Field with the Anisotropy of the Extragalactic Gamma-ray Background

    Science.gov (United States)

    Venters, T. M.; Pavlidou, V.

    2013-01-01

    The intergalactic magnetic field (IGMF) may leave an imprint on the angular anisotropy of the extragalactic gamma-ray background through its effect on electromagnetic cascades triggered by interactions between very high energy photons and the extragalactic background light. A strong IGMF will deflect secondary particles produced in these cascades and will thus tend to isotropize lower energy cascade photons, thereby inducing a modulation in the anisotropy energy spectrum of the gamma-ray background. Here we present a simple, proof-of-concept calculation of the magnitude of this effect and demonstrate that current Fermi data already seem to prefer nonnegligible IGMF values. The anisotropy energy spectrum of the Fermi gamma-ray background could thus be used as a probe of the IGMF strength.

  9. INVERSE CASCADE OF NONHELICAL MAGNETIC TURBULENCE IN A RELATIVISTIC FLUID

    Energy Technology Data Exchange (ETDEWEB)

    Zrake, Jonathan [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Menlo Park, CA 94025 (United States)

    2014-10-20

    The free decay of nonhelical relativistic magnetohydrodynamic turbulence is studied numerically, and found to exhibit cascading of magnetic energy toward large scales. Evolution of the magnetic energy spectrum P{sub M} (k, t) is self-similar in time and well modeled by a broken power law with subinertial and inertial range indices very close to 7/2 and –2, respectively. The magnetic coherence scale is found to grow in time as t {sup 2/5}, much too slow to account for optical polarization of gamma-ray burst afterglow emission if magnetic energy is to be supplied only at microphysical length scales. No bursty or explosive energy loss is observed in relativistic MHD turbulence having modest magnetization, which constrains magnetic reconnection models for rapid time variability of GRB prompt emission, blazars, and the Crab nebula.

  10. Development of the NPL gamma-ray spectrometer NANA for traceable nuclear decay and structure studies.

    Science.gov (United States)

    Lorusso, G; Shearman, R; Regan, P H; Judge, S M; Bell, S; Collins, S M; Larijani, C; Ivanov, P; Jerome, S M; Keightley, J D; Lalkovski, S; Pearce, A K; Podolyak, Zs

    2016-03-01

    We present a brief report on the progress towards the construction of the National Nuclear Array (NANA), a gamma-ray coincidence spectrometer for discrete-line nuclear structure and decay measurements. The proposed spectrometer will combine a gamma-ray energy resolution of approximately 3% at 1MeV with sub-nanosecond timing discrimination between successive gamma rays in mutually coincident decay cascades. We also review a number of recent measurements using coincidence fast-timing gamma-ray spectroscopy for nuclear structure studies, which have helped to inform the design criteria for the NANA spectrometer.

  11. DISTURBANCE ATTENUATION FOR UNCERTAIN NONLINEAR CASCADED SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    BI Weiping; MU Xiaowu; SUN Yuqiang

    2004-01-01

    In present paper, the disturbance attenuation problem of uncertain nonlinear cascaded systems is studied. Based on the adding one power integrator technique and recursive design, a feedback controller that solves the disturbance attenuation problem is constructed for uncertain nonlinear cascaded systems with internal stability.

  12. Cascade Harvest’ red raspberry

    Science.gov (United States)

    Cascade Harvest’ is a new floricane fruiting raspberry cultivar (Rubus idaeus L.) jointly released by Washington State University (WSU), Oregon State University (OSU) and the U.S. Department of Agriculture (USDA). ‘Cascade Harvest’ produces a high yield of large, firm fruit suited to machine harves...

  13. A NOTE ON VECTOR CASCADE ALGORITHM

    Institute of Scientific and Technical Information of China (English)

    Qiu-hui Chen; Jin-zhao Liu; Wen-sheng Zhang

    2002-01-01

    The focus of this paper is on the relationship between accuracy of multivariate refinable vector and vector cascade algorithm. We show that, if the vector cascade algorithm (1.5) with isotropic dilation converges to a vector-valued function with regularity, then the initial function must satisfy the Strang-Fix conditions.

  14. Cascading costs: An economic nitrogen cycle

    Institute of Scientific and Technical Information of China (English)

    William R. Moomaw; Melissa B. L. Birch

    2005-01-01

    The chemical nitrogen cycle is becoming better characterized in terms of fluxes and reservoirs on a variety of scales. Galloway has demonstrated that reactive nitrogen can cascade through multiple ecosystems causing environmental damage at each stage before being denitrifled to N2. We propose to construct a parallel economic nitrogen cascade (ENC) in which economic impacts of nitrogen fluxes can be estimated by the costs associated with each stage of the chemical cascade. Using economic data for the benefits of damage avoided and costs of mitigation in the Chesapeake Bay basin, we have constructed an economic nitrogen cascade for the region. Since a single tonne of nitrogen can cascade through the system, the costs also cascade.Therefore evaluating the benefits of mitigating a tonne of reactive nitrogen released needs to consider the damage avoided in all of the ecosystems through which that tonne would cascade.The analysis reveals that it is most cost effective to remove a tonne of nitrogen coming from combustion since it has the greatest impact on human health and creates cascading damage through the atmospheric, terrestrial, aquatic and coastal ecosystems. We will discuss the implications of this analysis for determining the most cost effective policy option for achieving environmental quality goals.

  15. Multifunctional Cascaded Metamaterials: Integrated Transmitarrays

    CERN Document Server

    Elsakka, Amr A; Faniayeu, Ihar A; Tcvetkova, Svetlana N; Tretyakov, Sergei A

    2016-01-01

    Control of electromagnetic waves using engineered materials is very important in a wide range of applications, therefore there is always a continuous need for new and more efficient solutions. Known natural and artificial materials and surfaces provide a particular functionality in the frequency range they operate but cast a "shadow" and produce reflections at other frequencies. Here, we introduce a concept of multifunctional engineered materials that possess different predetermined functionalities at different frequencies. Such response can be accomplished by cascading metasurfaces (thin composite layers) that are designed to perform a single operation at the desired frequency and are transparent elsewhere. Previously, out-of-band transparent metasurfaces for control over reflection and absorption were proposed. In this paper, to complete the full set of functionalities for wave control, we synthesize transmitarrays that tailor transmission in a desired way, being "invisible" beyond the operational band. The...

  16. Network reconstruction from infection cascades

    CERN Document Server

    Braunstein, Alfredo

    2016-01-01

    Reconstructing propagation networks from observations is a fundamental inverse problem, and it's crucial to understand and control dynamics in complex systems. Here we show that it is possible to reconstruct the whole structure of an interaction network and to simultaneously infer the complete time course of activation spreading, relying just on single snapshots of a small number of activity cascades. The method, that we called Inverse Dynamics Network Reconstruction (IDNR), is shown to work successfully on several synthetic and real networks, inferring the networks and the sources of infection based on sparse observations, including single snapshots. IDNR is built on a Belief Propagation approximation, that has an impressive performance in a wide variety of topological structures. The method can be applied in absence of complete time-series data by providing a detailed modeling of the posterior distribution of trajectories conditioned to the observations. Furthermore, we show by experiments that the informat...

  17. Availability Cascades & the Sharing Economy

    DEFF Research Database (Denmark)

    Netter, Sarah

    2015-01-01

    In search of a new concept that will provide answers to as to how modern societies should not only make sense but also resolve the social and environmental problems linked with our modes of production and consumption, collaborative consumption and the sharing economy are increasingly attracting...... attention. This conceptual paper attempts to explain the emergent focus on the sharing economy and associated business and consumption models by applying cascade theory. Risks associated with this behavior will be especially examined with regard to the sustainability claim of collaborative consumption....... With academics, practitioners, and civil society alike having a shared history in being rather fast in accepting new concepts that will not only provide business opportunities but also a good conscience, this study proposes a critical study of the implications of collaborative consumption, before engaging...

  18. Availability Cascades & the Sharing Economy

    DEFF Research Database (Denmark)

    Netter, Sarah

    2014-01-01

    In search of a new concept that will provide answers to as to how modern societies should not only make sense but also resolve the social and environmental problems linked with our modes of production and consumption, collaborative consumption and the sharing economy are increasingly attracting...... attention. This conceptual paper attempts to explain the emergent focus on the sharing economy and associated business and consumption models by applying cascade theory. Risks associated with this behavior will be especially examined with regard to the sustainability claim of collaborative consumption....... With academics, practitioners, and civil society alike having a shared history in being rather fast in accepting new concepts that will not only provide business opportunities but also a good conscience, this study proposes a critical study of the implications of collaborative consumption, before engaging...

  19. Cascades in interdependent flow networks

    CERN Document Server

    Scala, Antonio; Caldarelli, Guido; D'Agostino, Gregorio

    2015-01-01

    We investigate the abrupt breakdown behavior of coupled distribution grids under load growth. This scenario mimics the ever-increasing customer demand and the foreseen introduction of energy hubs interconnecting the different energy vectors. We extend an analytical model of cascading behavior due to line overloads to the case of interdependent networks and find evidence of first order transitions due to the long-range nature of the flows. Our results indicate that the foreseen increase in the couplings between the grids has two competing effects: on the one hand, it increases the safety region where grids can operate without withstanding systemic failures; on the other hand, it increases the possibility of a joint systems' failure.

  20. MAPK Cascades in Guard Cell Signal Transduction

    Science.gov (United States)

    Lee, Yuree; Kim, Yun Ju; Kim, Myung-Hee; Kwak, June M.

    2016-01-01

    Guard cells form stomata on the epidermis and continuously respond to endogenous and environmental stimuli to fine-tune the gas exchange and transpirational water loss, processes which involve mitogen-activated protein kinase (MAPK) cascades. MAPKs form three-tiered kinase cascades with MAPK kinases and MAPK kinase kinases, by which signals are transduced to the target proteins. MAPK cascade genes are highly conserved in all eukaryotes, and they play crucial roles in myriad developmental and physiological processes. MAPK cascades function during biotic and abiotic stress responses by linking extracellular signals received by receptors to cytosolic events and gene expression. In this review, we highlight recent findings and insights into MAPK-mediated guard cell signaling, including the specificity of MAPK cascades and the remaining questions. PMID:26904052

  1. MAPK cascades in guard cell signal transduction

    Directory of Open Access Journals (Sweden)

    Yuree eLee

    2016-02-01

    Full Text Available Guard cells form stomata on the epidermis and continuously respond to endogenous and environmental stimuli to fine-tune the gas exchange and transpirational water loss, processes which involve mitogen-activated protein kinase (MAPK cascades. MAPKs form three-tiered kinase cascades with MAPK kinases and MAPK kinase kinases, by which signals are transduced to the target proteins. MAPK cascade genes are highly conserved in all eukaryotes, and they play crucial roles in myriad developmental and physiological processes. MAPK cascades function during biotic and abiotic stress responses by linking extracellular signals received by receptors to cytosolic events and gene expression. In this review, we highlight recent findings and insights into MAPK-mediated guard cell signaling, including the specificity of MAPK cascades and the remaining questions.

  2. Gamma-ray strength functions in thermally excited rotating nuclei

    CERN Document Server

    Døssing, T; Maj, A; Matsuo, M; Vigezzi, E; Bracco, A; Leoni, S; Broglia, R A

    2001-01-01

    A general discussion and illustration is given of strength functions for rotational transitions in two-dimensional E(gamma_1) x E(gamma_2) spectra. Especially, a narrow component should be proportional to the compound damping width, related to the mixing of basis rotational bands into compound bands with fragmented transition strength. Three E(gamma_1) x E(gamma_2) spectra are made by setting gates on triple coincidences, selecting cascades which feed into specific low-lying bands in the nucleus 168Hf. In each of the gated spectra, we find a ridge, carrying about 100 decay paths. This ridge is ascribed to rotational transitions in the excitation energy range of 1.0 to 1.5 MeV above the yrast line. The FWHM of the ridges are around 40 keV, about a factor of two smaller than calculated on the basis of mixed cranked mean field bands.

  3. Stochastic Gyroresonant Acceleration for Hard Electron Spectra of Blazars: Effect of Damping of Cascading Turbulence

    CERN Document Server

    Kakuwa, Jun

    2015-01-01

    Stochastic acceleration of nonthermal electrons is investigated in the context of hard photon spectra of blazars. It is well known that this acceleration mechanism can produce a hard electron spectrum of $m \\equiv \\partial \\ln n_{\\rm e}(\\gamma)/\\partial \\ln \\gamma = 2$ with the high-energy cutoff, called an ultrarelativistic Maxwellian-like distribution, where $n_{\\rm e}(\\gamma)$ is an electron energy spectrum. We revisit the formation of this characteristic spectrum, considering a particular situation where the electrons are accelerated through gyroresonant interaction with magnetohydrodynamic wave turbulence driven by the turbulent cascade. By solving kinetic equations of the turbulent fields, electrons, and photons emitted via the synchrotron self-Compton (SSC) process, we demonstrate that in the non-test-particle treatment, the formation of a Maxwellian-like distribution is prevented by the damping effect on the turbulent fields due to the electron acceleration, at least unless an extreme parameter value ...

  4. Cascade Hierarchy in SUSY SU(5) GUT

    CERN Document Server

    Kojima, Kentaro; Takahashi, Ryo

    2010-01-01

    We study cascade hierarchy in supersymmetric SU(5) grand unified theory. The neutrino Dirac mass matrix of the cascade form can lead to the tri-bimaximal generation mixing at the leading order in the seesaw mechanism while the down quark mass matrix of a hybrid cascade form naturally gives the CKM structure. We embed such experimentally favored mass textures into supersymmetric SU(5) GUT, which gives a relation between the down quark and charged lepton mass matrices. Related phenomenologies, such as lepton flavor violating processes and leptogenesis, are also investigated in addition to lepton mixing angles.

  5. Cascades on clique-based graphs

    Science.gov (United States)

    Hackett, Adam; Gleeson, James P.

    2013-06-01

    We present an analytical approach to determining the expected cascade size in a broad range of dynamical models on the class of highly clustered random graphs introduced by Gleeson [J. P. Gleeson, Phys. Rev. EPLEEE81539-375510.1103/PhysRevE.80.036107 80, 036107 (2009)]. A condition for the existence of global cascades is also derived. Applications of this approach include analyses of percolation, and Watts's model. We show how our techniques can be used to study the effects of in-group bias in cascades on social networks.

  6. Gamma-Hadron Separation in Very-High-Energy gamma-ray astronomy using a multivariate analysis method

    CERN Document Server

    Ohm, Stefan; Egberts, Kathrin

    2009-01-01

    In recent years, Imaging Atmospheric Cherenkov Telescopes (IACTs) have discovered a rich diversity of very high energy (VHE, > 100 GeV) gamma-ray emitters in the sky. These instruments image Cherenkov light emitted by gamma-ray induced particle cascades in the atmosphere. Background from the much more numerous cosmic-ray cascades is efficiently reduced by considering the shape of the shower images, and the capability to reduce this background is one of the key aspects that determine the sensitivity of a IACT. In this work we apply a tree classification method to data from the High Energy Stereoscopic System (H.E.S.S.). We show the stability of the method and its capabilities to yield an improved background reduction compared to the H.E.S.S. Standard Analysis.

  7. Gamma radiation in the decay of 67Ga

    NARCIS (Netherlands)

    Rietjens, L.H.Th.; Bold, H.J. van den

    1955-01-01

    The level scheme of 67Zn has been investigated by scintillation coincidence spectrometry. Angular correlation measurements of the 206 keV – 182 keV and 485 keV − 296 keV gamma cascades result in anisotropies of − 0.216 ± 0.008 and +0.27 ± 0.05. The following spins have been allocated to the levels

  8. Quantum Cascade Laser Frequency Combs

    CERN Document Server

    Faist, Jérôme; Scalari, Giacomo; Rösch, Markus; Bonzon, Christopher; Hugi, Andreas; Beck, Mattias

    2015-01-01

    It was recently demonstrated that broadband quantum cascade lasers can operate as frequency combs. As such, they operate under direct electrical pumping at both mid-infrared and THz frequencies, making them very attractive for dual-comb spectroscopy. Performance levels are continuously improving, with average powers over 100 mW and frequency coverage of 100 cm$^{-1}$ in the mid-infrared. In the THz range, 10 mW of average power and 600 GHz of frequency coverage are reported. As a result of the very short upper state lifetime of the gain medium, the mode proliferation in these sources arises from four wave mixing rather than saturable absorption. As a result, their optical output is characterized by the tendency of small intensity modulation of the output power, and the relative phases of the modes to be similar to the ones of a frequency modulated laser. Recent results include the proof of comb operation down to a metrological level, the observation of a Schawlow-Townes broadened linewidth, as well as the fir...

  9. North Cascades Grizzly Bear Ecosystem Evaluation

    Data.gov (United States)

    Oak Ridge National Laboratory — We conducted a 6-year evaluation of the North Cascades Grizzly Bear Ecosystem (NCGBE) in north-central Washington to determine the suitability of the area to support...

  10. Multilevel Inverter by Cascading Industrial VSI

    DEFF Research Database (Denmark)

    Teodorescu, Remus; Blaabjerg, Frede; Pedersen, John Kim

    2002-01-01

    In this paper the modularity concept applied to medium-voltage adjustable speed drives is addressed. First, the single-phase cascaded voltage-source inverter that uses series connection of IGBT H-bridge modules with isolated dc-buses is presented. Next, a novel three-phase cascaded voltage...... of the motor rated kVA. The concept of using cascaded inverters is further extended to a new modular motor-modular inverter system where the motor winding connections are reconnected into several three-phase groups, either six-lead or 12-lead connection according to the voltage level, each powered...... by a standard triphase IGBT inverter module. Thus, a high fault tolerance is being achieved and the output transformer requirement is eliminated. A staggered space-vector modulation technique applicable to three-phase cascaded voltage-source inverter topologies is also demonstrated. Both computer simulations...

  11. Cascade of period doublings of tori

    Science.gov (United States)

    Arneodo, A.; Coullet, P. H.; Spiegel, E. A.

    1983-02-01

    A three-dimensional map is proposed to model the effects of periodic forcing on a system displaying a transition to chaos through a cascade of period-doubling bifurcations. The study outlined here raises the problem of the existence and bifurcation of invariant tori. A principal feature of the simulations of both the differential equations and the discrete dynamical systems is that it is possible to disrupt period-doubling sequences (and inverse sequences as well) by periodic external forcing. Even though the way in which this abortion works is not understood, the mechanism is thought to be associated with the destruction of tori (Aronson et al., 1982) when the system is on the verge of bifurcation. The simulations therefore suggest that in moving farther along the cascade, the tori become more fragile. It is suspected that for arbitrarily weak driving, the cascade will eventually be disrupted after the cascade has proceeded through a sufficient number of steps.

  12. Bursting behaviours in cascaded stimulated Brillouin scattering

    Institute of Scientific and Technical Information of China (English)

    Liu Zhan-Jun; He Xian-Tu; Zheng Chun-Yang; Wang Yu-Gang

    2012-01-01

    Stimulated Brillouin scattering is studied by numerically solving the Vlasov-Maxwell system.A cascade of stimulated Brillouin scattering can occur when a linearly polarized laser pulse propagates in a plasma.It is found that a stimulated Brillouin scattering cascade can reduce the scattering and increase the transmission of light,as well as introduce a bursting behaviour in the evolution of the laser-plasma interaction.The bursting time in the reflectivity is found to be less than half the ion acoustic period.The ion temperature can affect the stimulated Brillouin scattering cascade,which can repeat several times at low ion temperatures and can be completely eliminated at high ion temperatures.For stimulated Brillouin scattering saturation,higher-harmonic generation and wave-wave interaction of the excited ion acoustic waves can restrict the amplitude of the latter.In addition,stimulated Brillouin scattering cascade can restrict the amplitude of the scattered light.

  13. Picturing perturbative parton cascades in QCD matter

    Directory of Open Access Journals (Sweden)

    Aleksi Kurkela

    2015-01-01

    Full Text Available Based on parametric reasoning, we provide a simple dynamical picture of how a perturbative parton cascade, in interaction with a QCD medium, fills phase space as a function of time.

  14. MAP kinase cascades in Arabidopsis innate immunity

    DEFF Research Database (Denmark)

    Rasmussen, Magnus Wohlfahrt; Roux, Milena Edna; Petersen, Morten

    2012-01-01

    Plant mitogen-activated protein kinase (MAPK) cascades generally transduce extracellular stimuli into cellular responses. These stimuli include the perception of pathogen-associated molecular patterns (PAMPs) by host transmembrane pattern recognition receptors which trigger MAPK-dependent innate ...

  15. Chemoenzymatic cascade processes for sustainable organic synthesis

    NARCIS (Netherlands)

    Simons, C.

    2007-01-01

    Chemical production processes often require wasteful and expensive isolation as well as purification of intermediates. Catalytic cascades offer a unique opportunity to eliminate these inefficient and polluting steps, in particular when carefully orchestrated, involving enzymes and chemocatalysts. Th

  16. Model for cascading failures in congested Internet

    Institute of Scientific and Technical Information of China (English)

    Jian WANG; Yan-heng LIU; Jian-qi ZHU; Yu JIAO

    2008-01-01

    Cascading failures often occur in congested networks such as the Internet. A cascading failure can be described as a three-phase process: generation, diffusion, and dissipation of the congestion. In this account, we present a function that represents the extent of congestion on a given node. This approach is different from existing functions based on betweenness centrality. By introducing the concept of 'delay time', we designate an intergradation between permanent removal and nouremoval. We also construct an evaluation function of network efficiency, based on congestion, which measures the damage caused by cascading failures. Finally, we investigate the effects of network structure and size, delay time, processing ability and packet generation speed on congestion propagation. Also, we uncover the relationship between the cascade dynamics and some properties of the network such as structure and size.

  17. Transport properties of cascading gauge theories

    CERN Document Server

    Buchel, A

    2005-01-01

    Cascading gauge theories of Klebanov et.al. provide a model within a framework of gauge theory/string theory duality for a four dimensional non-conformal gauge theory with a spontaneously generated mass scale. Using the dual supergravity description we study sound wave propagation in strongly coupled cascading gauge theory plasma. We analytically compute the speed of sound and the bulk viscosity of cascading gauge theory plasma at a temperature much larger than the strong coupling scale of the theory. The sound wave dispersion relation is obtained from the hydrodynamic pole in the stress-energy tensor two-point correlation function. The speed of sound extracted from the pole of the correlation function agrees with its value computed in [hep-th/0506002] using the equation of state. We find that the bulk viscosity of the hot cascading gauge theory plasma is non-zero at the leading order in the deviation from conformality.

  18. A quantum cascade phonon-polariton laser

    CERN Document Server

    Ohtani, Keita; Bosco, Lorenzo; Beck, Mattias; Faist, Jérôme

    2016-01-01

    We report a laser that coherently emits phonon-polaritons, quasi-particles arising from the coupling between photons and transverse optical phonons. The gain is provided by an intersubband transition in a quantum cascade structure. The polaritons at h$\

  19. Innovation cascades: artefacts, organization and attributions.

    Science.gov (United States)

    Lane, David A

    2016-03-19

    Innovation cascades inextricably link the introduction of new artefacts, transformations in social organization, and the emergence of new functionalities and new needs. This paper describes a positive feedback dynamic, exaptive bootstrapping, through which these cascades proceed, and the characteristics of the relationships in which the new attributions that drive this dynamic are generated. It concludes by arguing that the exaptive bootstrapping dynamic is the principal driver of our current Innovation Society.

  20. Cascade Textures and SUSY SO(10) GUT

    CERN Document Server

    Adulpravitchai, Adisorn; Takahashi, Ryo

    2010-01-01

    We give texture analyses of cascade hierarchical mass matrices in supersymmetric SO(10) grand unified theory. We embed cascade mass textures of the standard model fermion with right-handed neutrinos into the theory, which gives relations among the mass matrices of the fermions. The related phenomenologies, such as the lepton flavor violating processes and leptogenesis, are also investigated in addition to the PMNS mixing angles.

  1. Supersonic Chordwise Bending Flutter in Cascades

    Science.gov (United States)

    1975-05-31

    such a flutter boundary can be made by utilizing the trend lines predicted from a supersonic analysis based on supersonic cascade theory (Appendix I...bonding agent was injected via hypodermic needles after the blade tabs were properly inserted, The integrity and repeatability of the mounting of the indi...in conjunction with NASTRAN predictions and supersonic cascade aerodynamic computa- tions. Comparisons between theory and experiment are discussed. DD

  2. Compression limits in cascaded quadratic soliton compression

    DEFF Research Database (Denmark)

    Bache, Morten; Bang, Ole; Krolikowski, Wieslaw;

    2008-01-01

    Cascaded quadratic soliton compressors generate under optimal conditions few-cycle pulses. Using theory and numerical simulations in a nonlinear crystal suitable for high-energy pulse compression, we address the limits to the compression quality and efficiency.......Cascaded quadratic soliton compressors generate under optimal conditions few-cycle pulses. Using theory and numerical simulations in a nonlinear crystal suitable for high-energy pulse compression, we address the limits to the compression quality and efficiency....

  3. GammaWorkshops Proceedings

    DEFF Research Database (Denmark)

    Strålberg, Elisabeth; Klemola, Seppo; Nielsen, Sven Poul;

    Due to a sparse interaction during the last years between practioners in gamma ray spectrometry in the Nordic countries, a NKS activity was started in 2009. This GammaSem was focused on seminars relevant to gamma spectrometry. A follow up seminar was held in 2010. As an outcome of these activitie...

  4. Emergence of event cascades in inhomogeneous networks

    Science.gov (United States)

    Onaga, Tomokatsu; Shinomoto, Shigeru

    2016-09-01

    There is a commonality among contagious diseases, tweets, and neuronal firings that past events facilitate the future occurrence of events. The spread of events has been extensively studied such that the systems exhibit catastrophic chain reactions if the interaction represented by the ratio of reproduction exceeds unity; however, their subthreshold states are not fully understood. Here, we report that these systems are possessed by nonstationary cascades of event-occurrences already in the subthreshold regime. Event cascades can be harmful in some contexts, when the peak-demand causes vaccine shortages, heavy traffic on communication lines, but may be beneficial in other contexts, such that spontaneous activity in neural networks may be used to generate motion or store memory. Thus it is important to comprehend the mechanism by which such cascades appear, and consider controlling a system to tame or facilitate fluctuations in the event-occurrences. The critical interaction for the emergence of cascades depends greatly on the network structure in which individuals are connected. We demonstrate that we can predict whether cascades may emerge, given information about the interactions between individuals. Furthermore, we develop a method of reallocating connections among individuals so that event cascades may be either impeded or impelled in a network.

  5. Quantum Cascade Photonic Crystal lasers

    Science.gov (United States)

    Capasso, Federico

    2004-03-01

    QC lasers have emerged in recent years as the dominant laser technology for the mid-to far infrared spectrum in light of their room temperature operation, their tunability, ultrahigh speed operation and broad range of applications to chemical sensing, spectroscopy etc. (Ref. 1-3). After briefly reviewing the latter, I will describe a new class of mid-infrared QC lasers, Quantum Cascade Photonic Crystal Surface Emitting Lasers (QCPCSELS), that combine electronic and photonic band structure engineering to achieve vertical emission from the surface (Ref. 4). Devices operating on bandedge mode and on defect modes will be discussed. Exciting potential uses of these new devices exist in nonlinear optics, microfluidics as well as novel sensors. Finally a bird's eye view of other exciting areas of QC laser research will be given including broadband QCLs and new nonlinear optical sources based on multiwavelength QCLs. 1. F. Capasso, C. Gmachl, D. L. Sivco, and A. Y. Cho, Physics Today 55, 34 (May 2002) 2. F. Capasso, C. Gmachl, R. Paiella, A. Tredicucci, A. L. Hutchinson, D. L. Sivco, J. N. Baillargeon, A. Y. Cho and H. C. Liu, IEEE Journal of Selected Topics in Quantum Electronics, 6, 931 (2000). 3. F. Capasso, R. Paiella, R. Martini, R. Colombelli, C. Gmachl, T. L. Myers, M. S. Taubman, R. M. Williams, C. G. Bethea, K. Unterrainer, H. Y. Hwang, D. L. Sivco, A. Y. Cho, A. M. Sergent, H. C. Liu, E. A. Whittaker, IEEE J. Quantum Electron. 38, 511 (2002) 4. R. Colombelli, K. Srivasan, M. Troccoli, O. Painter, C. Gmachl, D. M. Tennant, A. M. Sergent, D. L. Sivco, A. Y. Cho and F. Capasso, Science 302, 1374 (2003)

  6. Rehabilitation of gamma

    Science.gov (United States)

    Poynton, Charles A.

    1998-07-01

    Gamma characterizes the reproduction of tone scale in an imaging system. Gamma summarizes, in a single numerical parameter, the nonlinear relationship between code value--in an 8-bit system, from 0 through 255--and physical intensity. Nearly all image coding systems are nonlinear, and so involve values of gamma different from unity. Owing to poor understanding of tone scale reproduction, and to misconceptions about nonlinear coding, gamma has acquired a terrible reputation in computer graphics and image processing. In addition, the world-wide web suffers from poor reproduction of grayscale and color images, due to poor handling of nonlinear image coding. This paper aims to make gamma respectable again.

  7. Period-doubling cascades for large perturbations of Henon families

    OpenAIRE

    Sander, Evelyn; Yorke, James A.

    2009-01-01

    The Henon family has been shown to have period-doubling cascades. We show here that the same occurs for a much larger class: Large perturbations do not destroy cascades. Furthermore, we can classify the period of a cascade in terms of the set of orbits it contains, and count the number of cascades of each period. This class of families extends a general theory explaining why cascades occur.

  8. QED-PIC simulations of electromagnetic cascades at the surface of pulsar's polar cap

    Science.gov (United States)

    Grismayer, Thomas; Vranic, Marija; Fonseca, Ricardo; Silva, Luis

    2016-10-01

    The recent implementation of the QED module in the OSIRIS 3.0 framework has enabled to simulate various scenarios where pair production or gamma-rays emission can be produced with ultra-intense lasers and/or relativistic particles beams. In this study we leverage on these numerical tools to study extreme astrophysical scenarios where self-consistent produced electron-positron pair plasmas are of relevance such as in pulsar magnetospheres. The dynamics of pulsar's polar cap cascade, based on the Ruderman-Sutherland model, has been investigated for the first time numerically in one dimension by Timokhin. Including quantum synchrotron radiation additionally to curvature photon radiation for the possible processes responsible for photon emission, we present the results of one and two dimensional QED-PIC simulations of the development of electromagnetic cascades at the surface of the polar cap and the subsequent plasma discharges that are accompanied by strong electrostatic waves.

  9. Search for Extended {\\gamma}-ray Emission around AGN with H.E.S.S. and Fermi-LAT

    CERN Document Server

    Abramowski, A; Benkhali, F Ait; Akhperjanian, A G; Angüner, E; Anton, G; Backes, M; Balenderan, S; Balzer, A; Barnacka, A; Becherini, Y; Tjus, J Becker; Bernlöhr, K; Birsin, E; Bissaldi, E; Biteau, J; Böttcher, M; Boisson, C; Bolmont, J; Bordas, P; Brucker, J; Brun, F; Brun, P; Bulik, T; Carrigan, S; Casanova, S; Chadwick, P M; Chalme-Calvet, R; Chaves, R C G; Cheesebrough, A; Chrétien, M; Colafrancesco, S; Cologna, G; Conrad, J; Couturier, C; Cui, Y; Dalton, M; Daniel, M K; Davids, I D; Degrange, B; Deil, C; deWilt, P; Dickinson, H J; Djannati-Ataï, A; Domainko, W; Drury, L O'C; Dubus, G; Dutson, K; Dyks, J; Dyrda, M; Edwards, T; Egberts, K; Eger, P; Espigat, P; Farnier, C; Fegan, S; Feinstein, F; Fernandes, M V; Fernandez, D; Fiasson, A; Fontaine, G; Förster, A; Füßling, M; Gajdus, M; Gallant, Y A; Garrigoux, T; Giavitto, G; Giebels, B; Glicenstein, J F; Grondin, M -H; Grudzińska, M; Häffner, S; Hahn, J; Harris, J; Heinzelmann, G; Henri, G; Hermann, G; Hervet, O; Hillert, A; Hinton, J A; Hofmann, W; Hofverberg, P; Holler, M; Horns, D; Jacholkowska, A; Jahn, C; Jamrozy, M; Janiak, M; Jankowsky, F; Jung, I; Kastendieck, M A; Katarzyński, K; Katz, U; Kaufmann, S; Khélifi, B; Kieffer, M; Klepser, S; Klochkov, D; Kluźniak, W; Kneiske, T; Kolitzus, D; Komin, Nu; Kosack, K; Krakau, S; Krayzel, F; Krüger, P P; Laffon, H; Lamanna, G; Lefaucheur, J; Lemière, A; Lemoine-Goumard, M; Lenain, J -P; Lohse, T; Lopatin, A; Lu, C -C; Marandon, V; Marcowith, A; Marx, R; Maurin, G; Maxted, N; Mayer, M; McComb, T J L; Méhault, J; Meintjes, P J; Menzler, U; Meyer, M; Moderski, R; Mohamed, M; Moulin, E; Murach, T; Naumann, C L; de Naurois, M; Niemiec, J; Nolan, S J; Oakes, L; Odaka, H; Ohm, S; Wilhelmi, E de Oña; Opitz, B; Ostrowski, M; Oya, I; Panter, M; Parsons, R D; Arribas, M Paz; Pekeur, N W; Pelletier, G; Perez, J; Petrucci, P -O; Peyaud, B; Pita, S; Poon, H; Pühlhofer, G; Punch, M; Quirrenbach, A; Raab, S; Raue, M; Reichardt, I; Reimer, A; Reimer, O; Renaud, M; Reyes, R de los; Rieger, F; Rob, L; Romoli, C; Rosier-Lees, S; Rowell, G; Rudak, B; Rulten, C B; Sahakian, V; Sanchez, D A; Santangelo, A; Schlickeiser, R; Schüssler, F; Schulz, A; Schwanke, U; Schwarzburg, S; Schwemmer, S; Sol, H; Spengler, G; Spies, F; Stawarz, Ł; Steenkamp, R; Stegmann, C; Stinzing, F; Stycz, K; Sushch, I; Tavernet, J -P; Tavernier, T; Taylor, A M; Terrier, R; Tluczykont, M; Trichard, C; Valerius, K; van Eldik, C; van Soelen, B; Vasileiadis, G; Venter, C; Viana, A; Vincent, P; Völk, H J; Volpe, F; Vorster, M; Vuillaume, T; Wagner, S J; Wagner, P; Ward, M; Weidinger, M; Weitzel, Q; White, R; Wierzcholska, A; Willmann, P; Wörnlein, A; Wouters, D; Yang, R; Zabalza, V; Zacharias, M; Zdziarski, A A; Zech, A; Zechlin, H -S; Malyshev, D

    2014-01-01

    Context: Very-high-energy (VHE; E>100 GeV) {\\gamma}-ray emission from blazars inevitably gives rise to electron-positron pair production through the interaction of these {\\gamma}-rays with the Extragalactic Background Light (EBL). Depending on the magnetic fields in the proximity of the source, the cascade initiated from pair production can result in either an isotropic halo around an initially beamed source or a magnetically broadened cascade flux. Aims: Both extended pair halo (PH) and magnetically broadened cascade (MBC) emission from regions surrounding the blazars 1ES 1101-232, 1ES 0229+200 and PKS 2155-304 were searched for, using VHE {\\gamma}-ray data taken with the High Energy Stereoscopic System (H.E.S.S.), and high energy (HE; 100 MeV 10$^{-12}$G, this limits the production of pair halos developing from electromagnetic cascades. For weaker magnetic fields, in which electromagnetic cascades would result in magnetically broadened cascades, EGMF strengths in the range (0.3 - 3)$\\times 10^{-15}$G were e...

  10. Cascade reactions catalyzed by metal organic frameworks.

    Science.gov (United States)

    Dhakshinamoorthy, Amarajothi; Garcia, Hermenegildo

    2014-09-01

    Cascade or tandem reactions where two or more individual reactions are carried out in one pot constitute a clear example of process intensification, targeting the maximization of spatial and temporal productivity with mobilization of minimum resources. In the case of catalytic reactions, cascade processes require bi-/multifunctional catalysts that contain different classes of active sites. Herein, we show that the features and properties of metal-organic frameworks (MOFs) make these solids very appropriate materials for the development of catalysts for cascade reactions. Due to composition and structure, MOFs can incorporate different types of sites at the metal nodes, organic linkers, or at the empty internal pores, allowing the flexible design and synthesis of multifunctional catalysts. After some introductory sections on the relevance of cascade reactions from the point of view of competitiveness, sustainability, and environmental friendliness, the main part of the text provides a comprehensive review of the literature reporting the use of MOFs as heterogeneous catalysts for cascade reactions including those that combine in different ways acid/base, oxidation/reduction, and metal-organic centers. The final section summarizes the current state of the art, indicating that the development of a first commercial synthesis of a high-added-value fine chemical will be a crucial milestone in this area.

  11. Metamaterials for novel X- or gamma-ray detector designs

    CERN Document Server

    Lecoq, P

    2009-01-01

    In the majority of X and gamma ray conversion detector heads there is generally a trade-off between the spatial and the energy resolution, as a good spatial resolution requires a high segmentation whereas a good energy resolution is obtained in a large enough detector volume to contain all the cascade interactions generated by the incoming particle. The quest for better spatial resolution in all three dimensions for the majority of applications (High-energy physics and particle detectors, Spectrometry of low energy gamma-quanta, Medical imaging, Homeland security, Space applications) may lead to a huge increase of the number of readout channels, with all the associated problems of connectivity, detector integration and heat dissipation. This paper explores the potential of recent progress in the field of crystallogenesis, quantum dots and photonics crystals towards a new concept of X- and gamma-ray detector based on metamaterials to simultaneously record with high precision the maximum of information of the c...

  12. Measurement of. gamma. gamma. widths of charmonium states

    Energy Technology Data Exchange (ETDEWEB)

    Chen, W.Y.; McIlwain, R.L.; Miller, D.H.; Ng, C.R.; Schaffner, S.F.; Shibata, E.I.; Yao, W.M. (Purdue Univ., Lafayette, IN (USA)); Sparks, K.; Thorndike, E.H.; Wang, C.H. (Rochester Univ., NY (USA)); Alam, M.S.; Kim, I.J.; Li, W.C.; Lou, X.C.; Sun, C.R.; Wang, P.N.; Zoeller, M.I. (State Univ. of New York, Albany (USA)); Bortoletto, D.; Goldberg, M.; Horwitz, N.; Jain, V.; Mestayer, M.D.; Moneti, G.C.; Sharma, V.; Shipsey, I.P.J.; Skwarnicki, T.; Thulasidas, M. (Syracuse Univ., NY (USA)); Csorna, S.E.; Letson, T. (Vanderbilt Univ., Nashville, TN (USA)); Alexander, J.; Artuso, M.; Bebek, C.; Berkelman, K.; Cassel, D.G.; Cheu, E.; Coffman, D.M.; Crawford, G.; DeWire, J.W.; Dell, P.S.; Ehrlich, R.; Galik, R.S.; Gittelman, B.; Gray, S.W.; Halling, A.M.; Hartill, D.L.; Heltsley, B.K.; Kandaswamy, J.; Katayama, N.; Kreinick, D.L.; Lewis, J.D.; Mistry, N.B.; Mueller, J.; Namjoshi, R.; Nandi, S.; Nordberg, E.; O' Grady, C.; Peterson, D.; Pisharody, M.; Riley, D.; Sapper, M.; Silverman, A.

    1990-06-21

    Using the CLEO detector at the Cornell Electron Storage Ring, we have searched for two-phonon production of charmonium in four-track final states. We have measured {Gamma}{sub {gamma}{gamma}}({eta}{sub c})=5.9{sub -1.8}{sup +2.1}{plus minus}1.9 keV, and we have obtained 95% CL upper limits of {Gamma}{sub {gamma}{gamma}}({chi}{sub c0})<6.2 keV and {Gamma}{sub {gamma}{gamma}}({chi}{sub c2})<1.0 keV. (orig.).

  13. Spectra of {gamma} rays feeding superdeformed bands

    Energy Technology Data Exchange (ETDEWEB)

    Lauritsen, T.; Khoo, T.L.; Henry, R.G. [and others

    1995-08-01

    The spectrum of {gamma}rays coincident with SD transitions contains the transitions which populate the SD band. This spectrum can provide information on the feeding mechanism and on the properties (moment of inertia, collectivity) of excited SD states. We used a model we developed to explain the feeding of SD bands, to calculate the spectrum of feeding {gamma}rays. The Monte Carlo simulations take into account the trigger conditions present in our Eurogam experiment. Both experimental and theoretical spectra contain a statistical component and a broad E2 peak (from transitions occurring between excited states in the SD well). There is good resemblance between the measured and calculated spectra although the calculated multiplicity of an E2 bump is low by {approximately}30%. Work is continuing to improve the quality of the fits, which will result in a better understanding of excited SD states. In addition, a model for the last steps, which cool the {gamma} cascade into the SD yrast line, needs to be developed. A strong M1/E2 low-energy component, which we believe is responsible for this cooling, was observed.

  14. Emergence of event cascades in inhomogeneous networks

    CERN Document Server

    Onaga, Tomokatsu

    2016-01-01

    There is a commonality among contagious diseases, tweets, urban crimes, nuclear reactions, and neuronal firings that past events facilitate the future occurrence of events. The spread of events has been extensively studied such that the systems exhibit catastrophic chain reactions if the interaction represented by the ratio of reproduction exceeds unity; however, their subthreshold states for the case of the weaker interaction are not fully understood. Here, we report that these systems are possessed by nonstationary cascades of event-occurrences already in the subthreshold regime. Event cascades can be harmful in some contexts, when the peak-demand causes vaccine shortages, heavy traffic on communication lines, frequent crimes, or large fluctuations in nuclear reactions, but may be beneficial in other contexts, such that spontaneous activity in neural networks may be used to generate motion or store memory. Thus it is important to comprehend the mechanism by which such cascades appear, and consider controlli...

  15. Epidemic and Cascading Survivability of Complex Networks

    CERN Document Server

    Manzano, Marc; Ripoll, Jordi; Fagertun, Anna Manolova; Torres-Padrosa, Victor; Pahwa, Sakshi; Scoglio, Caterina

    2014-01-01

    Our society nowadays is governed by complex networks, examples being the power grids, telecommunication networks, biological networks, and social networks. It has become of paramount importance to understand and characterize the dynamic events (e.g. failures) that might happen in these complex networks. For this reason, in this paper, we propose two measures to evaluate the vulnerability of complex networks in two different dynamic multiple failure scenarios: epidemic-like and cascading failures. Firstly, we present \\emph{epidemic survivability} ($ES$), a new network measure that describes the vulnerability of each node of a network under a specific epidemic intensity. Secondly, we propose \\emph{cascading survivability} ($CS$), which characterizes how potentially injurious a node is according to a cascading failure scenario. Then, we show that by using the distribution of values obtained from $ES$ and $CS$ it is possible to describe the vulnerability of a given network. We consider a set of 17 different compl...

  16. Cascade enzymatic reactions for efficient carbon sequestration.

    Science.gov (United States)

    Xia, Shunxiang; Zhao, Xueyan; Frigo-Vaz, Benjamin; Zheng, Wenyun; Kim, Jungbae; Wang, Ping

    2015-04-01

    Thermochemical processes developed for carbon capture and storage (CCS) offer high carbon capture capacities, but are generally hampered by low energy efficiency. Reversible cascade enzyme reactions are examined in this work for energy-efficient carbon sequestration. By integrating the reactions of two key enzymes of RTCA cycle, isocitrate dehydrogenase and aconitase, we demonstrate that intensified carbon capture can be realized through such cascade enzymatic reactions. Experiments show that enhanced thermodynamic driving force for carbon conversion can be attained via pH control under ambient conditions, and that the cascade reactions have the potential to capture 0.5 mol carbon at pH 6 for each mole of substrate applied. Overall it manifests that the carbon capture capacity of biocatalytic reactions, in addition to be energy efficient, can also be ultimately intensified to approach those realized with chemical absorbents such as MEA.

  17. MAP Kinase Cascades in Plant Innate Immunity

    Directory of Open Access Journals (Sweden)

    Magnus Wohlfahrt Rasmussen

    2012-07-01

    Full Text Available Plant mitogen-activated protein kinase (MAPK cascades generally transduce extracellular stimuli into cellular responses. These stimuli include the perception of pathogen-associated molecular patterns (PAMPs by host transmembrane pattern recognition receptors (PRRs which trigger MAPK-dependent innate immune responses. In the model Arabidopsis, molecular genetic evidence implicates a number of MAPK cascade components in PAMP signaling, and in responses to immunity-related phytohormones such as ethylene, jasmonate and salicylate. In a few cases, cascade components have been directly linked to the transcription of target genes or to the regulation of phytohormone synthesis. Thus MAPKs are obvious targets for bacterial effector proteins and are likely guardees of resistance (R proteins, which mediate defense signaling in response to the action of effectors, or effector-triggered immunity (ETI. This mini-review discusses recent progress in this field with a focus on the Arabidopsis MAPKs MPK3, 4, 6 and 11 in their apparent pathways.

  18. Bifurcations analysis of turbulent energy cascade

    Energy Technology Data Exchange (ETDEWEB)

    Divitiis, Nicola de, E-mail: n.dedivitiis@gmail.com

    2015-03-15

    This note studies the mechanism of turbulent energy cascade through an opportune bifurcations analysis of the Navier–Stokes equations, and furnishes explanations on the more significant characteristics of the turbulence. A statistical bifurcations property of the Navier–Stokes equations in fully developed turbulence is proposed, and a spatial representation of the bifurcations is presented, which is based on a proper definition of the fixed points of the velocity field. The analysis first shows that the local deformation can be much more rapid than the fluid state variables, then explains the mechanism of energy cascade through the aforementioned property of the bifurcations, and gives reasonable argumentation of the fact that the bifurcations cascade can be expressed in terms of length scales. Furthermore, the study analyzes the characteristic length scales at the transition through global properties of the bifurcations, and estimates the order of magnitude of the critical Taylor-scale Reynolds number and the number of bifurcations at the onset of turbulence.

  19. Gamma radiation in space and in the atmosphere; Rayonnement gamma dans l'espace et dans l'atmosphere

    Energy Technology Data Exchange (ETDEWEB)

    Rocchia, R. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-07-01

    We have shown that the {gamma} radiation existing in the atmosphere is caused mainly by the Bremsstrahlung of the electrons of the electromagnetic cascades ({approx} 50 per cent of the measured radiation), by the 511 keV radiation produced by the annihilation of positrons created in cascades (8 per cent of the measured intensity) and by the Compton {gamma} degradation of this line (30 per cent of the measured intensity). The rest, slightly over 10 per cent, must be attributed to secondary causes such as the nuclear de-excitation {gamma} to the internal Bremsstrahlung of charged particles created in nuclear stars, and to charged particles crossing our detector, since the latter was not fitted with a device for rejecting these particles. Experiments carried out in rockets at Colomb-Bechar confirm these results and have made it possible to detect and measure a primary {gamma} radiation having an intensity of {approx} 2 {gamma} cm{sup 2} s{sup -1} above 100 keV. The primary spectrum obeys an approximate E{sup -2} law. (author) [French] Nous avons montre que le rayonnement {gamma} existant dans l'atmosphere est provoque principalement por le bremsstrohlung des electrons des cascades electromagnetiques ({approx} 50 pour cent du rayonnement mesure), au rayonnement 511 keV provoque par l'annihilation des positrons crees dans les cascades (8 pour cent de l'intensite mesuree) et aux {gamma} de degradation Compton de cette raie (30 pour cent de l'intensite mesuree). Le reste, soit un peu plus de 10 pour cent, doit etre attribue a des causes secondaires telles que les {gamma} de desexcitation nucleaire, le bremsstrahlung interne des particules chargees creees dans les etoiles nucleaires, et aux particules chargees traversant notre detecteur car celui-ci ne comportait pas de dispositif de rejet de ces particules. Les experiences faites en fusees a Colomb-Bechar ont confirme ces resultats et permis de detecter et mesurer un rayonnement {gamma} primaire dont l

  20. Piscivores, Trophic Cascades, and Lake Management

    Directory of Open Access Journals (Sweden)

    Ray W. Drenner

    2002-01-01

    Full Text Available The concept of cascading trophic interactions predicts that an increase in piscivore biomass in lakes will result in decreased planktivorous fish biomass, increased herbivorous zooplankton biomass, and decreased phytoplankton biomass. Though often accepted as a paradigm in the ecological literature and adopted by lake managers as a basis for lake management strategies, the trophic cascading interactions hypothesis has not received the unequivocal support (in the form of rigorous experimental testing that might be expected of a paradigm. Here we review field experiments and surveys, testing the hypothesis that effects of increasing piscivore biomass will cascade down through the food web yielding a decline in phytoplankton biomass. We found 39 studies in the scientific literature examining piscivore effects on phytoplankton biomass. Of the studies, 22 were confounded by supplemental manipulations (e.g., simultaneous reduction of nutrients or removal of planktivores and could not be used to assess piscivore effects. Of the 17 nonconfounded studies, most did not find piscivore effects on phytoplankton biomass and therefore did not support the trophic cascading interactions hypothesis. However, the trophic cascading interactions hypothesis also predicts that lake systems containing piscivores will have lower phytoplankton biomass for any given phosphorus concentration. Based on regression analyses of chlorophyll�total phosphorus relationships in the 17 nonconfounded piscivore studies, this aspect of the trophic cascading interactions hypothesis was supported. The slope of the chlorophyll vs. total phosphorus regression was lower in lakes with planktivores and piscivores compared with lakes containing only planktivores but no piscivores. We hypothesize that this slope can be used as an indicator of “functional piscivory” and that communities with extremes of functional piscivory (zero and very high represent classical 3- and 4-trophic level

  1. Cascaded logic gates in nanophotonic plasmon networks.

    Science.gov (United States)

    Wei, Hong; Wang, Zhuoxian; Tian, Xiaorui; Käll, Mikael; Xu, Hongxing

    2011-07-12

    Optical computing has been pursued for decades as a potential strategy for advancing beyond the fundamental performance limitations of semiconductor-based electronic devices, but feasible on-chip integrated logic units and cascade devices have not been reported. Here we demonstrate that a plasmonic binary NOR gate, a 'universal logic gate', can be realized through cascaded OR and NOT gates in four-terminal plasmonic nanowire networks. This finding provides a path for the development of novel nanophotonic on-chip processor architectures for future optical computing technologies.

  2. Cascade morphology transition in bcc metals.

    Science.gov (United States)

    Setyawan, Wahyu; Selby, Aaron P; Juslin, Niklas; Stoller, Roger E; Wirth, Brian D; Kurtz, Richard J

    2015-06-10

    Energetic atom collisions in solids induce shockwaves with complex morphologies. In this paper, we establish the existence of a morphological transition in such cascades. The order parameter of the morphology is defined as the exponent, b, in the defect production curve as a function of cascade energy (N(F) ~ E(MD)(b)). Response of different bcc metals can be compared in a consistent energy domain when the energy is normalized by the transition energy, μ, between the high- and the low-energy regime. Using Cr, Fe, Mo and W data, an empirical formula of μ as a function of displacement threshold energy, E(d), is presented for bcc metals.

  3. Cascaded impedance networks for NPC inverter

    DEFF Research Database (Denmark)

    Li, Ding; Gao, Feng; Loh, Poh Chiang;

    2010-01-01

    would have a higher output voltage gain. It is anticipated that it would help the formed inverters find applications in photovoltaic and other renewable systems, where a high voltage gain is usually requested. Experimental testing has already been conducted and verifies the theory. ©2010 IEEE....... they are subject to the renewable sources. To date, three distinct types of impedance networks can be summarized for implementing a hybrid source impedance network, which can in principle be combined and cascaded before connected to a NPC inverter by proposed two ways. The resulting cascaded impedance network NPC...

  4. Self-organized model of cascade spreading

    Science.gov (United States)

    Gualdi, S.; Medo, M.; Zhang, Y.-C.

    2011-01-01

    We study simultaneous price drops of real stocks and show that for high drop thresholds they follow a power-law distribution. To reproduce these collective downturns, we propose a minimal self-organized model of cascade spreading based on a probabilistic response of the system elements to stress conditions. This model is solvable using the theory of branching processes and the mean-field approximation. For a wide range of parameters, the system is in a critical state and displays a power-law cascade-size distribution similar to the empirically observed one. We further generalize the model to reproduce volatility clustering and other observed properties of real stocks.

  5. Self-organized model of cascade spreading

    CERN Document Server

    Gualdi, Stanislao; Zhang, Yi-Cheng

    2010-01-01

    We study simultaneous price drops of real stocks and show that for high drop thresholds they follow a power-law distribution. To reproduce these collective downturns, we propose a self-organized model of cascade spreading based on a probabilistic response of the system's elements to stress conditions. This model is solvable using the theory of branching processes and the mean-field approximation and displays a power-law cascade-size distribution-similar to the empirically observed one-over a wide range of parameters.

  6. Dynamics of Soliton Cascades in Fiber Amplifiers

    CERN Document Server

    Arteaga-Sierra, F R; Agrawal, Govind P

    2016-01-01

    We study numerically the formation of cascading solitons when femtosecond optical pulses are launched into a fiber amplifier with less energy than required to form a soliton of equal duration. As the pulse is amplified, cascaded fundamental solitons are created at different distances, without soliton fission, as each fundamental soliton moves outside the gain bandwidth through the Raman-induced spectral shifts. As a result, each input pulse creates multiple, temporally separated, ultrashort pulses of different wavelengths at the amplifier output. The number of pulses depends not only on the total gain of the amplifier but also on the width of input pulses.

  7. Energy cascade in internal wave attractors

    CERN Document Server

    Brouzet, Christophe; Joubaud, Sylvain; Sibgatullin, Ilias; Dauxois, Thierry

    2016-01-01

    One of the pivotal questions in the dynamics of the oceans is related to the cascade of mechanical energy in the abyss and its contribution to mixing. Here, we propose internal wave attractors in the large amplitude regime as a unique self-consistent experimental and numerical setup that models a cascade of triadic interactions transferring energy from large-scale monochro-matic input to multi-scale internal wave motion. We also provide signatures of a discrete wave turbulence framework for internal waves. Finally, we show how beyond this regime, we have a clear transition to a regime of small-scale high-vorticity events which induce mixing. Introduction.

  8. Distribution of photon strength in nuclei by a method of two-step cascades

    Energy Technology Data Exchange (ETDEWEB)

    Becvar, F.; Cejnar, P. (Karlova Univ., Prague (Czechoslovakia). Fakulta Matematicko-Fyzikalni); Chrien, R.E. (Brookhaven National Lab., Upton, NY (USA)); Kopecky, J. (Netherlands Energy Research Foundation, Petten (Netherlands))

    1990-01-01

    The applicability of sum-coincidence measurements of two-step cascade {gamma}-ray spectra to the determination of photon strength functions at intermediate {gamma}-ray energies (3 or 4 MeV) is discussed. An experiment based on thermal neutron capture in Nd was undertaken at the Brookhaven National Laboratory High Flux Beam Reactor to test this model. To understand the role of various uncertainties in similar experiments a series of model calculations was performed. We present an analysis of our experimental data which demonstrates the high sensitivity of the method to E1 and M1 photon strength functions. Our experimental data are in sharp contradiction to those expected from an E1 photon strength distributed according to the classical Lorentzian form with an energy invariant damping width. An alternative distribution of Kadmenskij et al., which violates Brink's Hypothesis, is strongly preferred. 13 refs., 5 figs.

  9. Beta and Gamma Gradients

    DEFF Research Database (Denmark)

    Løvborg, Leif; Gaffney, C. F.; Clark, P. A.;

    1985-01-01

    Experimental and/or theoretical estimates are presented concerning, (i) attenuation within the sample of beta and gamma radiation from the soil, (ii) the gamma dose within the sample due to its own radioactivity, and (iii) the soil gamma dose in the proximity of boundaries between regions...... of differing radioactivity. It is confirmed that removal of the outer 2 mm of sample is adequate to remove influence from soil beta dose and estimates are made of the error introduced by non-removal. Other evaluations include variation of the soil gamma dose near the ground surface and it appears...

  10. Development of a quantitative PCR for rapid and sensitive diagnosis of an intranuclear coccidian parasite in Testudines (TINC), and detection in the critically endangered Arakan forest turtle (Heosemys depressa).

    Science.gov (United States)

    Alvarez, W Alexander; Gibbons, Paul M; Rivera, Sam; Archer, Linda L; Childress, April L; Wellehan, James F X

    2013-03-31

    The intranuclear coccidian parasite of Testudines (TINC) is responsible for significant disease in turtles and tortoises causing high mortality and affecting several threatened species. Diagnostic testing has been limited to relatively labor intensive and expensive pan-coccidial PCR and sequencing techniques. A qPCR assay targeting a specific and conserved region of TINC 18S rRNA was designed. The qPCR reaction was run on samples known to be TINC positive and the results were consistent and analytically specific. The assay was able to detect as little as 10 copies of target DNA in a sample. Testing of soil and invertebrates was negative and did not provide any further insights into life cycles. This assay was used to identify TINC in a novel host species, the critically endangered Arakan forest turtle (Heosemys depressa).

  11. How the $\\gamma \\gamma$ Resonance Stole Christmas

    CERN Document Server

    Craig, Nathaniel; Kilic, Can; Thomas, Scott

    2015-01-01

    The experimental and theoretical implications of heavy di-gauge boson resonances that couple to, or are comprised of, new charged and strongly interacting matter are investigated. Observation and measurement of ratios of the resonant di-gauge boson channels $WW$, $ZZ$, $\\gamma \\gamma$, $Z \\gamma$, and $gg$ in the form of di-jets, provide a rather direct -- and for some ratios a rather robust -- probe of the gauge representations of the new matter. For a spin-zero resonance with the quantum numbers of the vacuum, the ratios of resonant $WW$ and $ZZ$ to $\\gamma \\gamma$ channels, as well as the longitudinal versus transverse polarization fractions in the $WW$ and $ZZ$ channels, provide extraordinarily sensitive probes for possible mixing with the Higgs boson, while di-Higgs and di-top resonant channels, $hh$ and $tt$, provide somewhat less sensitivity. We present a survey of possible underlying models for di-gauge boson resonances by considering various limits for the mass of the new charged and strongly interac...

  12. Quantum-engineered interband cascade photovoltaic devices

    Science.gov (United States)

    Yang, Rui Q.; Lotfi, Hossein; Li, Lu; Hinkey, Robert T.; Ye, Hao; Klem, John F.; Lei, L.; Mishima, T. D.; Keay, J. C.; Santos, M. B.; Johnson, M. B.

    2013-12-01

    Quantum-engineered multiple stage photovoltaic (PV) devices are explored based on InAs/GaSb/AlSb interband cascade (IC) structures. These ICPV devices employ multiple discrete absorbers that are connected in series by widebandgap unipolar barriers using type-II heterostructure interfaces for facilitating carrier transport between cascade stages similar to IC lasers. The discrete architecture is beneficial for improving the collection efficiency and for spectral splitting by utilizing absorbers with different bandgaps. As such, the photo-voltages from each individual cascade stage in an ICPV device add together, creating a high overall open-circuit voltage, similar to conventional multi-junction tandem solar cells. Furthermore, photo-generated carriers can be collected with nearly 100% efficiency in each stage. This is because the carriers travel over only a single cascade stage, designed to be shorter than a typical diffusion length. The approach is of significant importance for operation at high temperatures where the diffusion length is reduced. Here, we will present our recent progress in the study of ICPV devices, which includes the demonstration of ICPV devices at room temperature and above with narrow bandgaps (e.g. 0.23 eV) and high open-circuit voltages.

  13. Geothermal research, Oregon Cascades: Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Priest, G.R.; Black, G.L.

    1988-10-27

    Previous USDOE-funded geothermal studies have produced an extensive temperature gradient and heat flow data base for the State of Oregon. One of the important features identified as a result of these studies is a rapid transition from heat flow values on the order of 40 mW/m/sup 2/ in the Willamette Valley and Western Cascades to values of greater than or equal to100 mW/m/sup 2/ in the High Cascades and the eastern portion of the Western Cascades. These data indicate that the Cascade Range in Oregon has potential as a major geothermal province and stimulated much of the later work completed by government agencies and private industry. Additional data generated as a result of this grant and published in DOGAMI Open-File Report 0-86-2 further define the location and magnitude of this transition zone. In addition, abundant data collected from the vicinity of Breitenbush and Austin Hot Springs have permitted the formulation of relatively detailed models of these hydrothermal systems. These models are published in DOGAMI Open-File Report 0-88-5. Task 1.2 of the Deliverables section of Amendment M001 is fulfilled by DOGAMI publication GMS-48, Geologic map of the McKenzie Bridge quadrangle, Lane County, Oregon. This map was printed in October, 1988, and is part of the final submission to USDOE. 8 refs.

  14. Gene regulation by MAP kinase cascades

    DEFF Research Database (Denmark)

    Fiil, Berthe Katrine; Petersen, Klaus; Petersen, Morten

    2009-01-01

    Mitogen-activated protein kinase (MAPK) cascades are signaling modules that transduce extracellular stimuli to a range of cellular responses. Research in yeast and metazoans has shown that MAPK-mediated phosphorylation directly or indirectly regulates the activity of transcription factors. Plant ...

  15. Forecasting Social Unrest Using Activity Cascades.

    Science.gov (United States)

    Cadena, Jose; Korkmaz, Gizem; Kuhlman, Chris J; Marathe, Achla; Ramakrishnan, Naren; Vullikanti, Anil

    2015-01-01

    Social unrest is endemic in many societies, and recent news has drawn attention to happenings in Latin America, the Middle East, and Eastern Europe. Civilian populations mobilize, sometimes spontaneously and sometimes in an organized manner, to raise awareness of key issues or to demand changes in governing or other organizational structures. It is of key interest to social scientists and policy makers to forecast civil unrest using indicators observed on media such as Twitter, news, and blogs. We present an event forecasting model using a notion of activity cascades in Twitter (proposed by Gonzalez-Bailon et al., 2011) to predict the occurrence of protests in three countries of Latin America: Brazil, Mexico, and Venezuela. The basic assumption is that the emergence of a suitably detected activity cascade is a precursor or a surrogate to a real protest event that will happen "on the ground." Our model supports the theoretical characterization of large cascades using spectral properties and uses properties of detected cascades to forecast events. Experimental results on many datasets, including the recent June 2013 protests in Brazil, demonstrate the effectiveness of our approach.

  16. Modeling and simulation of cascading contingencies

    Science.gov (United States)

    Zhang, Jianfeng

    This dissertation proposes a new approach to model and study cascading contingencies in large power systems. The most important contribution of the work involves the development and validation of a heuristic analytic model to assess the likelihood of cascading contingencies, and the development and validation of a uniform search strategy. We model the probability of cascading contingencies as a function of power flow and power flow changes. Utilizing logistic regression, the proposed model is calibrated using real industry data. This dissertation analyzes random search strategies for Monte Carlo simulations and proposes a new uniform search strategy based on the Metropolis-Hastings Algorithm. The proposed search strategy is capable of selecting the most significant cascading contingencies, and it is capable of constructing an unbiased estimator to provide a measure of system security. This dissertation makes it possible to reasonably quantify system security and justify security operations when economic concerns conflict with reliability concerns in the new competitive power market environment. It can also provide guidance to system operators about actions that may be taken to reduce the risk of major system blackouts. Various applications can be developed to take advantage of the quantitative security measures provided in this dissertation.

  17. Nested Canalyzing, Unate Cascade, and Polynomial Functions.

    Science.gov (United States)

    Jarrah, Abdul Salam; Raposa, Blessilda; Laubenbacher, Reinhard

    2007-09-15

    This paper focuses on the study of certain classes of Boolean functions that have appeared in several different contexts. Nested canalyzing functions have been studied recently in the context of Boolean network models of gene regulatory networks. In the same context, polynomial functions over finite fields have been used to develop network inference methods for gene regulatory networks. Finally, unate cascade functions have been studied in the design of logic circuits and binary decision diagrams. This paper shows that the class of nested canalyzing functions is equal to that of unate cascade functions. Furthermore, it provides a description of nested canalyzing functions as a certain type of Boolean polynomial function. Using the polynomial framework one can show that the class of nested canalyzing functions, or, equivalently, the class of unate cascade functions, forms an algebraic variety which makes their analysis amenable to the use of techniques from algebraic geometry and computational algebra. As a corollary of the functional equivalence derived here, a formula in the literature for the number of unate cascade functions provides such a formula for the number of nested canalyzing functions.

  18. Cascading effects of overfishing marine systems

    NARCIS (Netherlands)

    Scheffer, M.; Carpenter, S.; Young, de B.

    2005-01-01

    Profound indirect ecosystem effects of overfishing have been shown for coastal systems such as coral reefs and kelp forests. A new study from the ecosystem off the Canadian east coast now reveals that the elimination of large predatory fish can also cause marked cascading effects on the pelagic food

  19. Transition Distribution Amplitudes for gamma* gamma collisions

    CERN Document Server

    Lansberg, J P; Szymanowski, L

    2008-01-01

    We study the exclusive production of pi-pi and rho-pi in hard gamma* gamma scattering in the forward kinematical region where the virtuality of one photon provides us with a hard scale in the process. The newly introduced concept of Transition Distribution Amplitudes (TDA) is used to perform a QCD calculation of these reactions thanks to two simple models for TDAs. The sizable cross sections for rho-pi and pi-pi production may be tested at intense electron-positron colliders such as CLEO and B factories (Belle and BaBar).

  20. Cascades with coupled map lattices in preferential attachment community networks

    Institute of Scientific and Technical Information of China (English)

    Cui Di; Gao Zi-You; Zhao Xiao-Mei

    2008-01-01

    In this paper,cascading failure is studied by coupled map lattice (CML) methods in preferential attachment community networks.It is found that external perturbation R is increasing with modularity Q growing by simulation.In particular,the large modularity Q can hold off the cascading failure dynamic process in community networks.Furthermore,different attack strategies also greatly affect the cascading failure dynamic process. It is particularly significant to control cascading failure process in real community networks.

  1. Detailed comparison between parton cascade and hadronic cascade at SPS and RHIC

    CERN Document Server

    Nara, Y; Longacre, R S

    1999-01-01

    We study the importance of the partonic phase produced in relativistic heavy ion collision by comparing the parton cascade model and the hadronic cascade model. Hadron yield, baryon stopping and transverse momentum distribution are calculated with JAM and discussions are given comparing with VNI. Both of these models give good description of experimental data. We also discuss the strangeness production mechanism and the directed transverse flow. (21 refs).

  2. Momentum Dependent Vertices $\\sigma \\gamma \\gamma$, $\\sigma \\rho \\gamma$ and $\\sigma \\rho \\rho$ : The NJL Scalar Hidden by Chiral Symmetry

    OpenAIRE

    Bajc, B.; Blin, A. H.; Hiller, B.; Nemes, M. C.; Rosina, M.

    1994-01-01

    We calculate the momentum dependence of three particle vertices $\\sigma \\gamma \\gamma$, $\\sigma \\rho \\gamma$ and $\\sigma \\rho \\rho$ in the context of a Nambu Jona Lasinio type model. We show how they influence the processes $\\gamma \\gamma \\rightarrow \\sigma \\rightarrow \\pi \\pi$, $\\rho \\rightarrow \\gamma \\sigma$ and $\\gamma \\gamma \\rightarrow \\rho \\rho$ and how chiral symmetry shadows the presence of the $\\sigma$.

  3. Colliding. gamma. e- and. gamma gamma. -beams on the basis of electron-positron linear colliders

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Serbo, V.G.; Tel' nov, V.I.

    1983-08-01

    Main properties of the ..gamma..e and ..gamma gamma.. collisions are discussed in some detail with application to the generation of colliding ..gamma..e and ..gamma gamma.. beams basing on the designed linear accelerators with colliding e/sup +/e/sup -/ beams, VLEEP and SLC, as it was proposed in a previous work. Intensive ..gamma.. beams with the energy 50 GeV would be produced from scattering of the laser light focused to the electron beams of the accelerators. Laser radiation is focused to the electron beam in the conversion region at a distance of about 10 cm from the place of collision. After scattering on electrons high-energy photons move practically along the electron primary trajectories and are focused in the collision region. The electrons are deflected from the collision region by means of approximately 1 T magnetic field. Then the produced ..gamma..-beam collides with an electron beam or a similar ..gamma..-beam. In the case when the maximum luminosity (L) is attained, the luminosity distribution in the invariant mass of the ..gamma..e or ..gamma gamma.. systems is wide. A monochromatization of the collisions up to the level of 5-10% is possible. That will entail a decrease in the luminosity, the procedure is most effective if one uses the electrons and the laser photons with opposite helicities. Examples of physically interesting problems to be investigated with the proposed ..gamma..e and ..gamma gamma.. beams are suggested.

  4. Star-forming galaxies as the origin of IceCube neutrinos: Reconciliation with Fermi-LAT gamma rays

    CERN Document Server

    Chakraborty, Sovan

    2016-01-01

    Cosmic ray accelerators like supernova and hypernova remnants in star forming galaxies are one of the most plausible sources of the IceCube observed diffuse astrophysical neutrinos. The neutrino producing hadronic processes will also produce a diffuse gamma ray flux, constrained by the Fermi-LAT bounds. The fact that point sources like blazars also contribute to the diffuse gamma ray flux implies large gamma opacity of the neutrino sources. Indeed, for these high redshift star forming galaxies the gamma absorption during the intergalactic propagation can be significant. In addition, large gamma attenuation inside these extreme source galaxies can reduce the cascade component of the diffuse flux. Under the current astrophysical uncertainties affecting these absorptions processes, we find the associated diffuse gamma ray flux can remain compatible with the current Fermi-LAT bounds.

  5. Gamma-ray spectroscopy of neutron-rich products of heavy-ion collisions

    Energy Technology Data Exchange (ETDEWEB)

    Carpenter, M.P.; Janssens, R.V.F.; Ahmad, I. [and others

    1995-08-01

    Thick-target {gamma}{gamma} coincidence techniques are being used to explore the spectroscopy of otherwise hard-to-reach neutron-rich products of deep-inelastic heavy ion reactions. Extensive {gamma}{gamma} coincidence measurements were performed at ATLAS using pulsed beams of {sup 80}Se, {sup 136}Xe, and {sup 238}U on lead-backed {sup 122,124}Sn targets with energies 10-15% above the Coulomb barrier. Gamma-ray coincidence intensities were used to map out yield distributions with A and Z for even-even product nuclei around the target and around the projectile. The main features of the yield patterns are understandable in terms of N/Z equilibration. We had the most success in studying the decays of yrast isomers. Thus far, more than thirty new {mu}s isomers in the Z = 50 region were found and characterized. Making isotopic assignments for previously unknown {gamma}-ray cascades proves to be one of the biggest problems. Our assignments were based (a) on rare overlaps with radioactivity data, (b) on the relative yields with different beams, and (c) on observed cross-coincidences between {gamma} rays from light and heavy reaction partners. However, the primary products of deep inelastic collisions often are sufficiently excited for subsequent neutron evaporation, so {gamma}{gamma} cross-coincidence results require careful interpretation.

  6. Upper Limit on the Cosmological Gamma-ray Background

    CERN Document Server

    Inoue, Yoshiyuki

    2012-01-01

    We show that the current extragalactic gamma-ray background (EGB) measurement below 100 GeV sets an upper limit on EGB itself at very high energy (VHE) above 100 GeV. The limit is conservative for the electromagnetic cascade emission from VHE EGB interacting with the cosmic microwave-to-optical background radiation not to exceed the current EGB measurement. The cascade component fits the measured VHE EGB spectrum rather well. However, once we add the contribution from known source classes, the Fermi VHE EGB observation exceeds or even violates the limit, which is approximated as E^2dN/dE < 4.5x10^-5 (E/100 GeV)^-0.7 MeV/cm^2/s/sr. The upper limit above 100 GeV is useful in the future to probe the EGB origin and the new physics like axion-like particles and Lorentz-invariance violation.

  7. GammaWorkshops Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Ramebaeck, H. (ed.) (Swedish Defence Research Agency (Sweden)); Straalberg, E. (Institute for Energy Technology, Kjeller (Norway)); Klemola, S. (Radiation and Nuclear Safety Authority, STUK (Finland)); Nielsen, Sven P. (Technical Univ. of Denmark. Risoe National Lab. for Sustainable Energy, Roskilde (Denmark)); Palsson, S.E. (Icelandic Radiation Safety Authority (Iceland))

    2012-01-15

    Due to a sparse interaction during the last years between practioners in gamma ray spectrometry in the Nordic countries, a NKS activity was started in 2009. This GammaSem was focused on seminars relevant to gamma spectrometry. A follow up seminar was held in 2010. As an outcome of these activities it was suggested that the 2011 meeting should be focused on practical issues, e.g. different corrections needed in gamma spectrometric measurements. This three day's meeting, GammaWorkshops, was held in September at Risoe-DTU. Experts on different topics relevant for gamma spectrometric measurements were invited to the GammaWorkshops. The topics included efficiency transfer, true coincidence summing corrections, self-attenuation corrections, measurement of natural radionuclides (natural decay series), combined measurement uncertainty calculations, and detection limits. These topics covered both lectures and practical sessions. The practical sessions included demonstrations of tools for e.g. corrections and calculations of the above meantioned topics. (Author)

  8. Higher-order Kerr effect and harmonic cascading in gases

    CERN Document Server

    Bache, Morten; Minardi, Stefano

    2012-01-01

    The higher-order Kerr effect (HOKE) has been recently advocated to explain measurements of the saturation of the nonlinear refractive index in gases. Here we show that cascaded third-harmonic generation results in an effective fifth order nonlinearity that is negative and significant. Higher-order harmonic cascading will also occur from the HOKE, and the cascading contributions may significantly modify the observed nonlinear index change. At lower wavelengths cascading increases the HOKE saturation intensity, while for longer wavelengths cascading will decrease the HOKE saturation intensity.

  9. The gamma function

    CERN Document Server

    Artin, Emil

    2015-01-01

    This brief monograph on the gamma function was designed by the author to fill what he perceived as a gap in the literature of mathematics, which often treated the gamma function in a manner he described as both sketchy and overly complicated. Author Emil Artin, one of the twentieth century's leading mathematicians, wrote in his Preface to this book, ""I feel that this monograph will help to show that the gamma function can be thought of as one of the elementary functions, and that all of its basic properties can be established using elementary methods of the calculus."" Generations of teachers

  10. Study of acoustic resonance of cascades

    Science.gov (United States)

    Honjo, M.; Tominaga, T.

    Discrete sounds and vibrations from guide vanes due to acoustic resonance in the vane flow path, are experimentally investigated. Other causes of pure sounds in stationary vanes are considered, such as direct radiation from wake shedding vortices, bubble vortices or leading edges, and radial or axial modes of air columns. Two-dimensional cascade tests are performed under various conditions, and the data are compared with theoretical results of flat plate cascades. Three-dimensional ducted guide vane model tests are carried out to apply prototype guide vanes, and to confirm the resonance of the two-dimensional tests. Results show that frequency is more sensitive to chord length than pitch length, and the ratio of the fluctuation frequency to fluid sound velocity/pitch length is independent of the scale. Bubble vortices on concave surfaces or leading edges are not exciting sources; and under the limit of solidity, no exciting energy can generate acoustic resonance in correspondence to the mode.

  11. Estimating Cascading Failure Risk with Random Chemistry

    CERN Document Server

    Rezaei, Pooya; Eppstein, Margaret J

    2014-01-01

    The potential for cascading failure in power systems adds substantially to overall reliability risk. Monte Carlo sampling can be used with a power system model to estimate this impact, but doing so is computationally expensive. This paper presents a new approach to estimating the risk of large cascading blackouts triggered by multiple contingencies. The method uses a search algorithm (Random Chemistry) to identify blackout-causing contingencies, and then combines the results with outage probabilities to estimate overall risk. Comparing this approach with Monte Carlo sampling for two test cases (the IEEE RTS-96 and a 2383 bus model of the Polish grid) suggests that the new approach is at least two orders of magnitude faster than Monte Carlo, without introducing measurable bias. Moreover, the approach enables one to compute the contribution of individual component-failure probabilities to overall blackout risk, allowing one to quickly identify low-cost strategies for reducing risk. By computing the sensitivity ...

  12. Cascade Apartments: Deep Energy Multifamily Retrofit

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, A. [Washington State Univ. Energy Program, Olympia, WA (United States); Mattheis, L. [Washington State Univ. Energy Program, Olympia, WA (United States); Kunkle, R. [Washington State Univ. Energy Program, Olympia, WA (United States); Howard, L. [Washington State Univ. Energy Program, Olympia, WA (United States); Lubliner, M. [Washington State Univ. Energy Program, Olympia, WA (United States)

    2014-02-01

    In December of 2009-10, King County Housing Authority (KCHA) implemented energy retrofit improvements in the Cascade multifamily community, located in Kent, Washington (marine climate.)This research effort involved significant coordination from stakeholders KCHA, WA State Department of Commerce, utility Puget Sound Energy, and Cascade tenants. This report focuses on the following three primary BA research questions: 1. What are the modeled energy savings using DOE low income weatherization approved TREAT software? 2. How did the modeled energy savings compare with measured energy savings from aggregate utility billing analysis? 3. What is the Savings to Investment Ratio (SIR) of the retrofit package after considering utility window incentives and KCHA capitol improvement funding.

  13. Cascade Apartments: Deep Energy Multifamily Retrofit

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, A.; Mattheis, L.; Kunkle, R.; Howard, L.; Lubliner, M.

    2014-02-01

    In December of 2009-10, King County Housing Authority (KCHA) implemented energy retrofit improvements in the Cascade multifamily community, located in Kent, Washington (marine climate.)This research effort involved significant coordination from stakeholders KCHA, WA State Department of Commerce, utility Puget Sound Energy, and Cascade tenants. This report focuses on the following three primary BA research questions : 1. What are the modeled energy savings using DOE low income weatherization approved TREAT software? 2. How did the modeled energy savings compare with measured energy savings from aggregate utility billing analysis? 3. What is the Savings to Investment Ratio (SIR) of the retrofit package after considering utility window incentives and KCHA capitol improvement funding.

  14. Cascaded trans-z-source inverters

    DEFF Research Database (Denmark)

    Li, Ding; Loh, Poh Chiang; Zhu, Miao;

    2011-01-01

    Z-source inverter is a recently proposed single-stage inverter with added voltage-boost capability for complementing the usual voltage-buck operation of a traditional voltage-source inverter. As long as the transformer element added in to the z-source concept, a trans-z-source inverter with one...... transformer and one capacitor is reported recently. This paper has adapted the cascaded concept into the trans-z-source and trans-quasi-z-source inverters to extend each to the cascaded topologies before combination is made with allowing more sources embedded which reduces the capacitor voltage and enhanced...... the compatibility for distributed sources. Unlike existing techniques, voltage stresses within the proposed inverters are better distributed among the passive components. Theoretical analysis for explaining these operating features has already been discussed before simulation were performed and an experimental...

  15. Regimes of turbulence without an energy cascade

    CERN Document Server

    Barenghi, C F; Baggaley, A W

    2016-01-01

    Experiments and numerical simulations of turbulent $^4$He and $^3$He-B have established that, at hydrodynamic length scales larger than the average distance between quantum vortices, the energy spectrum obeys the same 5/3 Kolmogorov law which is observed in the homogeneous isotropic turbulence of ordinary fluids. The importance of the 5/3 law is that it points to the existence of a Richardson energy cascade from large eddies to small eddies. However, there is also evidence of quantum turbulent regimes without Kolmogorov scaling. This raises the important questions of why, in such regimes, the Kolmogorov spectrum fails to form, what is the physical nature of turbulence without energy cascade, and whether hydrodynamical models can account for the unusual behaviour of turbulent superfluid helium. In this work we describe simple physical mechanisms which prevent the formation of Kolmogorov scaling in the thermal counterflow, and analyze the conditions necessary for emergence of quasiclassical regime in quantum tu...

  16. Short distance properties of cascading gauge theories

    CERN Document Server

    Aharony, O; Yarom, A; Aharony, Ofer; Buchel, Alex; Yarom, Amos

    2006-01-01

    We study the short distance (large momentum) properties of correlation functions of cascading gauge theories by performing a tree-level computation in their dual gravitational background. We prove that these theories are holographically renormalizable; the correlators have only analytic ultraviolet divergences, which may be removed by appropriate local counterterms. We find that n-point correlation functions of properly normalized operators have the expected scaling in the semi-classical gravity (large N) limit: they scale as N_{eff}^{2-n} with N_{eff} proportional to ln(k/Lambda) where k is a typical momentum. Our analysis thus confirms the interpretation of the cascading gauge theories as renormalizable four-dimensional quantum field theories with an effective number of degrees of freedom which logarithmically increases with the energy.

  17. Production of Medical Radioisotopes with High Specific Activity in Photonuclear Reactions with $\\gamma$ Beams of High Intensity and Large Brilliance

    CERN Document Server

    Habs, D

    2010-01-01

    We study the production of radioisotopes for nuclear medicine in $(\\gamma,x{\\rm n}+y{\\rm p})$ photonuclear reactions or ($\\gamma,\\gamma'$) photoexcitation reactions with high flux [($10^{13}-10^{15}$)$\\gamma$/s], small diameter $\\sim (100 \\, \\mu$m$)^2$ and small band width ($\\Delta E/E \\approx 10^{-3}-10^{-4}$) $\\gamma$ beams produced by Compton back-scattering of laser light from relativistic brilliant electron beams. We compare them to (ion,$x$n$ + y$p) reactions with (ion=p,d,$\\alpha$) from particle accelerators like cyclotrons and (n,$\\gamma$) or (n,f) reactions from nuclear reactors. For photonuclear reactions with a narrow $\\gamma$ beam the energy deposition in the target can be managed by using a stack of thin target foils or wires, hence avoiding direct stopping of the Compton and pair electrons (positrons). $(\\gamma,\\gamma')$ isomer production via specially selected $\\gamma$ cascades allows to produce high specific activity in multiple excitations, where no back-pumping of the isomer to the ground st...

  18. Transonic Cascade Measurements to Support Analytical Modeling

    Science.gov (United States)

    2007-11-02

    RECEIVED JUL 0 12005 FINAL REPORT FOR: AFOSR GRANT F49260-02-1-0284 TRANSONIC CASCADE MEASUREMENTS TO SUPPORT ANALYTICAL MODELING Paul A. Durbin ...PAD); 650-723-1971 (JKE) durbin @vk.stanford.edu; eaton@vk.stanford.edu submitted to: Attn: Dr. John Schmisseur Air Force Office of Scientific Research...both spline and control points for subsequent wall shape definitions. An algebraic grid generator was used to generate the grid for the blade-wall

  19. Toward Order-of-Magnitude Cascade Prediction

    OpenAIRE

    Guo, Ruocheng; Shaabani, Elham; Bhatnagar, Abhinav; Shakarian, Paulo

    2015-01-01

    When a piece of information (microblog, photograph, video, link, etc.) starts to spread in a social network, an important question arises: will it spread to "viral" proportions -- where "viral" is defined as an order-of-magnitude increase. However, several previous studies have established that cascade size and frequency are related through a power-law - which leads to a severe imbalance in this classification problem. In this paper, we devise a suite of measurements based on "structural dive...

  20. Adaptive stabilization for cascade nonlinear systems

    Institute of Scientific and Technical Information of China (English)

    陈岚萍; 王洪元; 吴波

    2004-01-01

    An adaptive controller of full state feedback for certain cascade nonlinear systems achieving input-to-state stability with respect to unknown bounded disturbance is designed using backstepping and control Lyapunov function (CLF)techniques. We show that unknown bounded disturbance can be estimated by update laws, which requires less information on unknown disturbance, as a part of stabilizing control. The design method achieves the desired property: global robust stability. Our contribution is illustrated with the example of a disturbed pendulum.

  1. Optical encryption with cascaded fractional wavelet transforms

    Institute of Scientific and Technical Information of China (English)

    BAO Liang-hua; CHEN Lin-fei; ZHAO Dao-mu

    2006-01-01

    On the basis of fractional wavelet transform, we propose a new method called cascaded fractional wavelet transform to encrypt images. It has the virtues of fractional Fourier transform and wavelet transform. Fractional orders, standard focal lengths and scaling factors are its keys. Multistage fractional Fourier transforms can add the keys easily and strengthen information security. This method can also realize partial encryption just as wavelet transform and fractional wavelet transform. Optical realization of encryption and decryption is proposed. Computer simulations confirmed its possibility.

  2. Controllability of nonlinear degenerate parabolic cascade systems

    Directory of Open Access Journals (Sweden)

    Mamadou Birba

    2016-08-01

    Full Text Available This article studies of null controllability property of nonlinear coupled one dimensional degenerate parabolic equations. These equations form a cascade system, that is, the solution of the first equation acts as a control in the second equation and the control function acts only directly on the first equation. We prove positive null controllability results when the control and a coupling set have nonempty intersection.

  3. Tip Clearance Flows in Turbine Cascades

    Institute of Scientific and Technical Information of China (English)

    Li Wei; Qiao Weiyang; Sun Dawei

    2008-01-01

    This article describes the effects of some factors on the tip clearance flow in axial linear turbine cascades.The measurements of the total pressure loss coefficient are made at the cascade outlets by using a five-hole probe at exit Mach numbers of 0.10,0.14 and 0.19.At each exit Mach number,experiments axe performed at the tip clearance heights of 1.0%,1.5%,2.0%,2.5% and 3.0% of the blade height.The effects of the non-uniform tip clearance height of each blade in the pitchwise direction are also studied.The results show that at a given tip clearance height,generally,total pressure loss rises with exit Mach numbers proportionally.At a fixed exit Mach number,the total pressure loss augments nearly proportionally as the tip clearance height increases.The increased tip clearance heights in the tip regions of two adjacent blades are to be blame for the larger clearance loss of the center blade.Compared to the effects of the tip clearance height,the effects of the exit Mach number and the pitchwise variation of the tip clearance height on the cascade total pressure loss are so less significant to be omitted.

  4. Cascade laser applications: trends and challenges

    Science.gov (United States)

    d'Humières, B.; Margoto, Éric; Fazilleau, Yves

    2016-03-01

    When analyses need rapid measurements, cost effective monitoring and miniaturization, tunable semiconductor lasers can be very good sources. Indeed, applications like on-field environmental gas analysis or in-line industrial process control are becoming available thanks to the advantage of tunable semiconductor lasers. Advances in cascade lasers (CL) are revolutionizing Mid-IR spectroscopy with two alternatives: interband cascade lasers (ICL) in the 3-6μm spectrum and quantum cascade lasers (QCL), with more power from 3 to 300μm. The market is getting mature with strong players for driving applications like industry, environment, life science or transports. CL are not the only Mid-IR laser source. In fact, a strong competition is now taking place with other technologies like: OPO, VCSEL, Solid State lasers, Gas, SC Infrared or fiber lasers. In other words, CL have to conquer a share of the Mid-IR application market. Our study is a market analysis of CL technologies and their applications. It shows that improvements of components performance, along with the progress of infrared laser spectroscopy will drive the CL market growth. We compare CL technologies with other Mid-IR sources and estimate their share in each application market.

  5. Cascading failures in ac electricity grids

    Science.gov (United States)

    Rohden, Martin; Jung, Daniel; Tamrakar, Samyak; Kettemann, Stefan

    2016-09-01

    Sudden failure of a single transmission element in a power grid can induce a domino effect of cascading failures, which can lead to the isolation of a large number of consumers or even to the failure of the entire grid. Here we present results of the simulation of cascading failures in power grids, using an alternating current (AC) model. We first apply this model to a regular square grid topology. For a random placement of consumers and generators on the grid, the probability to find more than a certain number of unsupplied consumers decays as a power law and obeys a scaling law with respect to system size. Varying the transmitted power threshold above which a transmission line fails does not seem to change the power-law exponent q ≈1.6 . Furthermore, we study the influence of the placement of generators and consumers on the number of affected consumers and demonstrate that large clusters of generators and consumers are especially vulnerable to cascading failures. As a real-world topology, we consider the German high-voltage transmission grid. Applying the dynamic AC model and considering a random placement of consumers, we find that the probability to disconnect more than a certain number of consumers depends strongly on the threshold. For large thresholds the decay is clearly exponential, while for small ones the decay is slow, indicating a power-law decay.

  6. HIV treatment cascade in tuberculosis patients

    Science.gov (United States)

    Lessells, Richard J.; Swaminathan, Soumya; Godfrey-Faussett, Peter

    2015-01-01

    Purpose of review Globally, the number of deaths associated with tuberculosis (TB) and HIV coinfection remains unacceptably high. We review the evidence around the impact of strengthening the HIV treatment cascade in TB patients and explore recent findings about how best to deliver integrated TB/HIV services. Recent findings There is clear evidence that the timely provision of antiretroviral therapy (ART) reduces mortality in TB/HIV coinfected adults. Despite this, globally in 2013, only around a third of known HIV-positive TB cases were treated with ART. Although there is some recent evidence exploring the barriers to achieve high coverage of HIV testing and ART initiation in TB patients, our understanding of which factors are most important and how best to address these within different health systems remains incomplete. There are some examples of good practice in the delivery of integrated TB/HIV services to improve the HIV treatment cascade. However, evidence of the impact of such strategies is of relatively low quality for informing integrated TB/HIV programming more broadly. In most settings, there remain barriers to higher-level organizational and functional integration. Summary There remains a need for commitment to patient-centred integrated TB/HIV care in countries affected by the dual epidemic. There is a need for better quality evidence around how best to deliver integrated services to strengthen the HIV treatment cascade in TB patients, both at primary healthcare level and within community settings. PMID:26352390

  7. Prediction of Cascading Failures in Spatial Networks.

    Science.gov (United States)

    Shunkun, Yang; Jiaquan, Zhang; Dan, Lu

    2016-01-01

    Cascading overload failures are widely found in large-scale parallel systems and remain a major threat to system reliability; therefore, they are of great concern to maintainers and managers of different systems. Accurate cascading failure prediction can provide useful information to help control networks. However, for a large, gradually growing network with increasing complexity, it is often impractical to explore the behavior of a single node from the perspective of failure propagation. Fortunately, overload failures that propagate through a network exhibit certain spatial-temporal correlations, which allows the study of a group of nodes that share common spatial and temporal characteristics. Therefore, in this study, we seek to predict the failure rates of nodes in a given group using machine-learning methods. We simulated overload failure propagations in a weighted lattice network that start with a center attack and predicted the failure percentages of different groups of nodes that are separated by a given distance. The experimental results of a feedforward neural network (FNN), a recurrent neural network (RNN) and support vector regression (SVR) all show that these different models can accurately predict the similar behavior of nodes in a given group during cascading overload propagation.

  8. Stereotactic radiosurgery - Gamma Knife

    Science.gov (United States)

    ... being treated. As compared to other types of radiation therapy, Gamma Knife treatment is much less likely to damage ... of radiosurgery alone vs radiosurgery with whole brain radiation ... Knife radiosurgery patient resource center. 2015. www.elekta. ...

  9. Dynamic gamma knife radiosurgery.

    Science.gov (United States)

    Luan, Shuang; Swanson, Nathan; Chen, Zhe; Ma, Lijun

    2009-03-21

    Gamma knife has been the treatment of choice for various brain tumors and functional disorders. Current gamma knife radiosurgery is planned in a 'ball-packing' approach and delivered in a 'step-and-shoot' manner, i.e. it aims to 'pack' the different sized spherical high-dose volumes (called 'shots') into a tumor volume. We have developed a dynamic scheme for gamma knife radiosurgery based on the concept of 'dose-painting' to take advantage of the new robotic patient positioning system on the latest Gamma Knife C and Perfexion units. In our scheme, the spherical high dose volume created by the gamma knife unit will be viewed as a 3D spherical 'paintbrush', and treatment planning reduces to finding the best route of this 'paintbrush' to 'paint' a 3D tumor volume. Under our dose-painting concept, gamma knife radiosurgery becomes dynamic, where the patient moves continuously under the robotic positioning system. We have implemented a fully automatic dynamic gamma knife radiosurgery treatment planning system, where the inverse planning problem is solved as a traveling salesman problem combined with constrained least-square optimizations. We have also carried out experimental studies of dynamic gamma knife radiosurgery and showed the following. (1) Dynamic gamma knife radiosurgery is ideally suited for fully automatic inverse planning, where high quality radiosurgery plans can be obtained in minutes of computation. (2) Dynamic radiosurgery plans are more conformal than step-and-shoot plans and can maintain a steep dose gradient (around 13% per mm) between the target tumor volume and the surrounding critical structures. (3) It is possible to prescribe multiple isodose lines with dynamic gamma knife radiosurgery, so that the treatment can cover the periphery of the target volume while escalating the dose for high tumor burden regions. (4) With dynamic gamma knife radiosurgery, one can obtain a family of plans representing a tradeoff between the delivery time and the dose

  10. Dynamic gamma knife radiosurgery

    Science.gov (United States)

    Luan, Shuang; Swanson, Nathan; Chen, Zhe; Ma, Lijun

    2009-03-01

    Gamma knife has been the treatment of choice for various brain tumors and functional disorders. Current gamma knife radiosurgery is planned in a 'ball-packing' approach and delivered in a 'step-and-shoot' manner, i.e. it aims to 'pack' the different sized spherical high-dose volumes (called 'shots') into a tumor volume. We have developed a dynamic scheme for gamma knife radiosurgery based on the concept of 'dose-painting' to take advantage of the new robotic patient positioning system on the latest Gamma Knife C™ and Perfexion™ units. In our scheme, the spherical high dose volume created by the gamma knife unit will be viewed as a 3D spherical 'paintbrush', and treatment planning reduces to finding the best route of this 'paintbrush' to 'paint' a 3D tumor volume. Under our dose-painting concept, gamma knife radiosurgery becomes dynamic, where the patient moves continuously under the robotic positioning system. We have implemented a fully automatic dynamic gamma knife radiosurgery treatment planning system, where the inverse planning problem is solved as a traveling salesman problem combined with constrained least-square optimizations. We have also carried out experimental studies of dynamic gamma knife radiosurgery and showed the following. (1) Dynamic gamma knife radiosurgery is ideally suited for fully automatic inverse planning, where high quality radiosurgery plans can be obtained in minutes of computation. (2) Dynamic radiosurgery plans are more conformal than step-and-shoot plans and can maintain a steep dose gradient (around 13% per mm) between the target tumor volume and the surrounding critical structures. (3) It is possible to prescribe multiple isodose lines with dynamic gamma knife radiosurgery, so that the treatment can cover the periphery of the target volume while escalating the dose for high tumor burden regions. (4) With dynamic gamma knife radiosurgery, one can obtain a family of plans representing a tradeoff between the delivery time and the

  11. Dynamic gamma knife radiosurgery

    Energy Technology Data Exchange (ETDEWEB)

    Luan Shuang; Swanson, Nathan; Chen Zhe [Department of Computer Science, University of New Mexico, Albuquerque, NM 87131 (United States); Ma Lijun [Department of Radiation Oncology, University of California San Francisco, San Francisco, CA 94143 (United States)], E-mail: sluan@cs.unm.edu, E-mail: nate@cs.unm.edu, E-mail: zchen@cs.unm.edu, E-mail: lijunma@radonc.ucsf.edu

    2009-03-21

    Gamma knife has been the treatment of choice for various brain tumors and functional disorders. Current gamma knife radiosurgery is planned in a 'ball-packing' approach and delivered in a 'step-and-shoot' manner, i.e. it aims to 'pack' the different sized spherical high-dose volumes (called 'shots') into a tumor volume. We have developed a dynamic scheme for gamma knife radiosurgery based on the concept of 'dose-painting' to take advantage of the new robotic patient positioning system on the latest Gamma Knife C(TM) and Perfexion(TM) units. In our scheme, the spherical high dose volume created by the gamma knife unit will be viewed as a 3D spherical 'paintbrush', and treatment planning reduces to finding the best route of this 'paintbrush' to 'paint' a 3D tumor volume. Under our dose-painting concept, gamma knife radiosurgery becomes dynamic, where the patient moves continuously under the robotic positioning system. We have implemented a fully automatic dynamic gamma knife radiosurgery treatment planning system, where the inverse planning problem is solved as a traveling salesman problem combined with constrained least-square optimizations. We have also carried out experimental studies of dynamic gamma knife radiosurgery and showed the following. (1) Dynamic gamma knife radiosurgery is ideally suited for fully automatic inverse planning, where high quality radiosurgery plans can be obtained in minutes of computation. (2) Dynamic radiosurgery plans are more conformal than step-and-shoot plans and can maintain a steep dose gradient (around 13% per mm) between the target tumor volume and the surrounding critical structures. (3) It is possible to prescribe multiple isodose lines with dynamic gamma knife radiosurgery, so that the treatment can cover the periphery of the target volume while escalating the dose for high tumor burden regions. (4) With dynamic gamma knife radiosurgery, one can

  12. Exclusive Photoproduction of the Cascade (Xi) Hyperons

    CERN Document Server

    Price, J W; Berman, B L; Laget, J M; Strauch, S; Adams, G; Afanasiev, A V; Ambrozewicz, P; Anghinolfi, M; Annand, J R M; Armstrong, C; Asavapibhop, B; Avakian, H; Bagdasaryan, H; Ball, J P; Barrow, S; Battaglieri, M; Beard, K; Bektasoglu, M; Bellis, M; Benmouna, N; Bianchi, N; Biselli, A S; Boiarinov, S; Bonner, B E; Bouchigny, S; Bradford, R; Branford, D; Briscoe, W J; Brooks, W K; Burkert, V D; Butuceanu, C; Calarco, J R; Carman, D S; Carnahan, B; Chen, S; Cole, P L; Coleman, A; Cords, D; Corvisiero, P; Crabb, D; Crannell, H; Cummings, J P; De Sanctis, E; De Vita, R; Degtyarenko, P V; Denizli, H; Dennis, L; Dharmawardane, K V; Dhuga, K S; Djalali, C; Dodge, G E; Doughty, D; Dragovitsch, P; Dugger, M; Dytman, S; Dzyubak, O P; Egiyan, H; Egiyan, K S; Elouadrhiri, L; Empl, A; Ent, R; Eugenio, P; Fatemi, R; Fedotov, G; Feldman, G; Feuerbach, R J; Ficenec, J; Forest, T A; Funsten, H; Gavalian, G; Gilfoyle, G P; Giovanetti, K L; Golovatch, E; Gordon, C I O; Gothe, R W; Griffioen, K; Guidal, M; Guillo, M R; Guler, N; Guo, L; Gyurjyan, V; Hadjidakis, C; Hakobyan, R S; Hardie, J; Heddle, D; Heimberg, P; Hersman, F W; Hicks, K; Hleiqawi, K; Holtrop, M; Hu, J; Huertas, M; Hyde-Wright, C E; Ilieva, Y Y; Ireland, D; Ito, M M; Jenkins, D; Jo, H S; Joo, K; Jüngst, H G; Kellie, J; Khandaker, M; Kim, K Y; Kim, K; Kim, W; Klein, A; Klein, F J; Klimenko, A V; Klusman, M; Kossov, M; Kramer, L H; Kuang, Y; Kuhn, S E; Kühn, J; Lachniet, J; Langheinrich, J; Lawrence, D; Ji Li; Lima, A C S; Livingston, K; Lukashin, K; Manak, J J; Marchand, C; McAleer, S; McNabb, J W C; Mecking, B A; Melone, J J; Mestayer, M D; Meyer, C A; Mikhailov, K; Minehart, R C; Mirazita, M; Miskimen, R; Morand, L; Morrow, S A; Muccifora, V; Müller, J; Murphy, L Y; Mutchler, G S; Napolitano, J; Nasseripour, R; Niccolai, S; Niculescu, G; Niculescu, I; Niczyporuk, B B; Niyazov, R A; Nozar, M; O'Brien, J T; O'Rielly, G V; Osipenko, M; Ostrovidov, A I; Park, K; Pasyuk, E A; Philips, S A; Pivnyuk, N; Pocanic, D; Pogorelko, O I; Polli, E; Popa, I; Pozdniakov, S; Preedom, B M; Prok, Y; Protopopescu, D; Qin, L M; Raue, B A; Riccardi, G; Ricco, G; Ripani, M; Ritchie, B G; Ronchetti, F; Rosner, G; Rossi, P; Rowntree, D; Rubin, P D; Sabatie, F; Salgado, C; Santoro, J P; Sapunenko, V; Schumacher, R A; Serov, V S; Shafi, A; Sharabyan, Yu G; Shaw, J; Skabelin, A V; Smith, E S; Smith, L C; Sober, D I; Stavinsky, A V; Stepanyan, S; Stoler, P; Strakovsky, I I; Suleiman, R; Taiuti, M; Taylor, S; Tedeschi, D J; Thoma, U; Thompson, R; Tkabladze, R; Todor, L; Tur, C; Ungaro, M; Vineyard, M F; Vlassov, A V; Wang, K; Weinstein, L B; Weygand, D P; Whisnant, C S; Williams, M; Wolin, E; Wood, M H; Yegneswaran, A; Yun, J; Zana, L

    2004-01-01

    We report on the first measurement of exclusive Xi-(1321) hyperon photoproduction in gamma p --> K+ K+ Xi- for 3.2 < E(gamma) < 3.9 GeV. The final state is identified by the missing mass in p(gamma,K+ K+)X measured with the CLAS detector at Jefferson Laboratory. We have detected a significant number of the ground-state Xi-(1321)1/2+, and have estimated the total cross section for its production. We have also observed the first excited state Xi-(1530)3/2+. Photoproduction provides a copious source of Xi's. We discuss the possibilities of a search for the recently proposed Xi5-- and Xi5+ pentaquarks.

  13. PLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migration.

    Science.gov (United States)

    Li, Siwei; Wang, Qian; Wang, Yi; Chen, Xinmei; Wang, Zhixiang

    2009-06-01

    It is well established that epidermal growth factor (EGF) induces the cytoskeleton reorganization and cell migration through two major signaling cascades: phospholipase C-gamma1 (PLC-gamma1) and Rho GTPases. However, little is known about the cross talk between PLC-gamma1 and Rho GTPases. Here we showed that PLC-gamma1 forms a complex with Rac1 in response to EGF. This interaction is direct and mediated by PLC-gamma1 Src homology 3 (SH3) domain and Rac1 (106)PNTP(109) motif. This interaction is critical for EGF-induced Rac1 activation in vivo, and PLC-gamma1 SH3 domain is actually a potent and specific Rac1 guanine nucleotide exchange factor in vitro. We have also demonstrated that the interaction between PLC-gamma1 SH3 domain and Rac1 play a significant role in EGF-induced F-actin formation and cell migration. We conclude that PLC-gamma1 and Rac1 coregulate EGF-induced cell cytoskeleton remodeling and cell migration by a direct functional interaction.

  14. Measurements of high-energy {gamma}-rays with LaBr{sub 3}:Ce detectors

    Energy Technology Data Exchange (ETDEWEB)

    Ciemala, M. [Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow (Poland)], E-mail: Michal.Ciemala@ifj.edu.pl; Balabanski, D. [INRNE, Bulgarian Academy of Sciences, BG-1784 Sofia (Bulgaria); Csatlos, M. [Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary); Daugas, J.M. [CEA, DAM, DIF, F-91297 Arpajon Cedex (France); Georgiev, G. [Centre de Spectrometrie Nucleaire et de Spectrometrie de Masse (CSNSM), IN2P3-CNRS and Universite Paris-Sud, Bat 104-108, F-91405 Orsay Cedex (France); Gulyas, J. [Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary); Kmiecik, M. [Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow (Poland); Krasznahorkay, A. [Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary); Lalkovski, S. [Faculty of Physics, University of Sofia, BG-1164 (Bulgaria); Lefebvre-Schuhl, A. [Centre de Spectrometrie Nucleaire et de Spectrometrie de Masse (CSNSM), IN2P3-CNRS and Universite Paris-Sud, Bat 104-108, F-91405 Orsay Cedex (France); Lozeva, R. [Instituut voor Kernen Stralingsfysica (IKS), Katholieke Universiteit Leuven, B-3001 Leuven (Belgium); Maj, A. [Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow (Poland); Vitez, A. [Institute of Nuclear Research of the Hungarian Academy of Sciences (ATOMKI), P.O. Box 51, H-4001 Debrecen (Hungary)

    2009-09-01

    The full-energy peak efficiency calibration and the energy resolution measurements of the 2in.x2in.LaBr{sub 3}{gamma}-ray detector are presented for {gamma}-ray energies in the 700 keV-17.6 MeV range. Measurements were done using a combination of proton-capture nuclear reactions on {sup 27}Al, {sup 23}Na, {sup 39}K, {sup 7}Li and {sup 11}B for high-energy {gamma}-rays, and radioactive sources such as {sup 60}Co and {sup 152}Eu for the lowest energies. At high energies, two {gamma}-rays in a cascade from proton resonance capture were employed using Al, Na{sub 2}WO{sub 4}, K{sub 2}SO{sub 4} and LiBO{sub 2} targets. The obtained results were compared to the simulations performed using a GEANT4 code.

  15. Characterizations of {\\Gamma}-AG^{**}-groupoids by their {\\Gamma}-ideals

    CERN Document Server

    Khan, Madad

    2010-01-01

    In this paper we have discusses {\\Gamma}-left, {\\Gamma}-right, {\\Gamma}-bi-, {\\Gamma}-quasi-, {\\Gamma}-interior and {\\Gamma}-ideals in {\\Gamma}-AG^{**}-groupoids and regular {\\Gamma}-AG^{**}-groupoids. Moreover we have proved that the set of {\\Gamma}-ideals in a regular {\\Gamma}-AG^{**}-groupoid form a semilattice structure. Also we have characterized a regular {\\Gamma}-AG^{**}-groupoid in terms of left ideals.

  16. Characterizations of gamma-AG^{**}-groupoids by the properties their gamma-ideals

    CERN Document Server

    Khan, Madad; Rehman, Inayatur

    2010-01-01

    In this paper we have discusses {\\Gamma}-left, {\\Gamma}-right, {\\Gamma}-bi-, {\\Gamma}-quasi-, {\\Gamma}-interior and {\\Gamma}-ideals in {\\Gamma}-AG^{**}-groupoids and regular {\\Gamma}-AG^{**}-groupoids. Moreover we have proved that the set of {\\Gamma}-ideals in a regular {\\Gamma}-AG^{**}-groupoid form a semilattice structure. Also we have characterized a regular {\\Gamma}-AG^{**}-groupoid in terms of left ideals.

  17. Ultra-bright GeV photon source via controlled electromagnetic cascades in laser-dipole waves

    CERN Document Server

    Gonoskov, A; Bastrakov, S; Efimenko, E; Ilderton, A; Kim, A; Marklund, M; Meyerov, I; Muraviev, A; Sergeev, A

    2016-01-01

    One aim of upcoming high-intensity laser facilities is to provide new high-flux gamma-ray sources. Electromagnetic cascades may serve for this, but are known to limit both field strengths and particle energies, restricting efficient production of photons to sub-GeV energies. Here we show how to create a directed GeV photon source, enabled by a controlled interplay between the cascade and anomalous radiative trapping. Using advanced 3D QED particle-in-cell (PIC) simulations and analytic estimates, we show that the concept is feasible for planned peak powers of 10 PW level. A higher peak power of 40 PW can provide $10^9$ photons with GeV energies in a well-collimated 3 fs beam, achieving peak brilliance ${9 \\times 10^{24}}$ ph s$^{-1}$mrad$^{-2}$mm$^{-2}$/0.1${\\%}$BW. Such a source would be a powerful tool for studying fundamental electromagnetic and nuclear processes.

  18. Implications of plasma beam instabilities for the statistics of the Fermi hard gamma-ray blazars and the origin of the extragalactic gamma-ray background

    Energy Technology Data Exchange (ETDEWEB)

    Broderick, Avery E. [Perimeter Institute for Theoretical Physics, 31 Caroline Street North, Waterloo, ON N2L 2Y5 (Canada); Pfrommer, Christoph; Puchwein, Ewald [Heidelberg Institute for Theoretical Studies, Schloss-Wolfsbrunnenweg 35, D-69118 Heidelberg (Germany); Chang, Philip [Department of Physics, University of Wisconsin-Milwaukee, 1900 East Kenwood Boulevard, Milwaukee, WI 53211 (United States)

    2014-08-01

    Fermi has been instrumental in constraining the luminosity function and redshift evolution of gamma-ray bright BL Lac objects, a subpopulation of blazars with almost featureless optical spectra. This includes limits on the spectrum and anisotropy of the extragalactic gamma-ray background (EGRB), redshift distribution of nearby Fermi active galactic nuclei (AGNs), and the construction of a logN-log S relation. Based on these, it has been argued that the evolution of the gamma-ray bright BL Lac population must be much less dramatic than that of other AGNs. However, critical to such claims is the assumption that inverse Compton cascades reprocess emission above a TeV into the Fermi energy range, substantially enhancing the strength of the observed limits. Here we demonstrate that in the absence of such a process, due, e.g., to the presence of virulent plasma beam instabilities that preempt the cascade, a population of TeV-bright BL Lac objects that evolve similarly to quasars is consistent with the population of hard gamma-ray BL Lac objects observed by Fermi. Specifically, we show that a simple model for the properties and luminosity function is simultaneously able to reproduce their logN-log S relation, local redshift distribution, and contribution to the EGRB and its anisotropy without any free parameters. Insofar as the naturalness of a picture in which the hard gamma-ray BL Lac population exhibits the strong redshift evolution observed in other tracers of the cosmological history of accretion onto halos is desirable, this lends support for the absence of the inverse Compton cascades and the existence of the beam plasma instabilities.

  19. Dynamics of quantum cascade lasers: numerics

    Science.gov (United States)

    Van der Sande, Guy; Verschaffelt, Guy

    2016-04-01

    Since the original demonstration of terahertz quantum-cascade lasers (QCLs), the performance of these devices has shown rapid improvement. QCLs can now deliver milliwatts or more of continuous-wave radiation throughout the terahertz frequency range (300 GHz to 10 THz). Therefore, QCLs have become widely used in various applications such as spectroscopy, metrology or free-space telecommunications. For many of these applications there is a need for compact tuneable quantum cascade lasers. Nowadays most tuneable QCLs are based on a bulky external cavity configuration. We explore the possibility of tuning the operating wavelength through a fully integrated on-chip wavelength selective feedback applied to a dual wavelength QCL. Our numerical and analytical analyses are based on rate equation models describing the dynamics of QCLs extended to include delayed filtered optical feedback. We demonstrate the possibility to tune the operating wavelength by altering the absorption and/or amplification of the signal in the delayed feedback path. The tuning range of a laser is limited by the spectral width of its gain. For inter-band semiconductor lasers this spectral width is typically several tens of nm. Hence, the laser cavity supports the existence of multiple modes and on chip wavelength selective feedback has been demonstrated to be a promising tuning mechanism. We have selected a specific QCL gain structure with four energy levels and with two lasing transitions in the same cascade. In this scheme, the two lasing modes use a common upper level. Hence, the two modes compete in part for the same carriers to account for their optical gain. We have added delayed wavelength specific filtered optical feedback to the rate equation model describing these transitions. We have calculated the steady states and their stability in the absence of delay for the feedback field and studied numerically the case with non-zero delay. We have proven that wavelength tuning of a dual wavelength

  20. Heat cascading regenerative sorption heat pump

    Science.gov (United States)

    Jones, Jack A. (Inventor)

    1995-01-01

    A simple heat cascading regenerative sorption heat pump process with rejected or waste heat from a higher temperature chemisorption circuit (HTCC) powering a lower temperature physisorption circuit (LTPC) which provides a 30% total improvement over simple regenerative physisorption compression heat pumps when ammonia is both the chemisorbate and physisorbate, and a total improvement of 50% or more for LTPC having two pressure stages. The HTCC contains ammonia and a chemisorbent therefor contained in a plurality of canisters, a condenser-evaporator-radiator system, and a heater, operatively connected together. The LTPC contains ammonia and a physisorbent therefor contained in a plurality of compressors, a condenser-evaporator-radiator system, operatively connected together. A closed heat transfer circuit (CHTC) is provided which contains a flowing heat transfer liquid (FHTL) in thermal communication with each canister and each compressor for cascading heat from the HTCC to the LTPC. Heat is regenerated within the LTPC by transferring heat from one compressor to another. In one embodiment the regeneration is performed by another CHTC containing another FHTL in thermal communication with each compressor. In another embodiment the HTCC powers a lower temperature ammonia water absorption circuit (LTAWAC) which contains a generator-absorber system containing the absorbent, and a condenser-evaporator-radiator system, operatively connected together. The absorbent is water or an absorbent aqueous solution. A CHTC is provided which contains a FHTL in thermal communication with the generator for cascading heat from the HTCC to the LTAWAC. Heat is regenerated within the LTAWAC by transferring heat from the generator to the absorber. The chemical composition of the chemisorbent is different than the chemical composition of the physisorbent, and the absorbent. The chemical composition of the FHTL is different than the chemisorbent, the physisorbent, the absorbent, and ammonia.

  1. Mixtures of multiplicative cascade models in geochemistry

    Directory of Open Access Journals (Sweden)

    F. P. Agterberg

    2007-05-01

    Full Text Available Multifractal modeling of geochemical map data can help to explain the nature of frequency distributions of element concentration values for small rock samples and their spatial covariance structure. Useful frequency distribution models are the lognormal and Pareto distributions which plot as straight lines on logarithmic probability and log-log paper, respectively. The model of de Wijs is a simple multiplicative cascade resulting in discrete logbinomial distribution that closely approximates the lognormal. In this model, smaller blocks resulting from dividing larger blocks into parts have concentration values with constant ratios that are scale-independent. The approach can be modified by adopting random variables for these ratios. Other modifications include a single cascade model with ratio parameters that depend on magnitude of concentration value. The Turcotte model, which is another variant of the model of de Wijs, results in a Pareto distribution. Often a single straight line on logarithmic probability or log-log paper does not provide a good fit to observed data and two or more distributions should be fitted. For example, geochemical background and anomalies (extremely high values have separate frequency distributions for concentration values and for local singularity coefficients. Mixtures of distributions can be simulated by adding the results of separate cascade models. Regardless of properties of background, an unbiased estimate can be obtained of the parameter of the Pareto distribution characterizing anomalies in the upper tail of the element concentration frequency distribution or lower tail of the local singularity distribution. Computer simulation experiments and practical examples are used to illustrate the approach.

  2. Gamma Ray Astronomy

    Science.gov (United States)

    Wu, S. T.

    2000-01-01

    The project has progressed successfully during this period of performance. The highlights of the Gamma Ray Astronomy teams efforts are: (1) Support daily BATSE data operations, including receipt, archival and dissemination of data, quick-look science analysis, rapid gamma-ray burst and transient monitoring and response efforts, instrument state-of-health monitoring, and instrument commanding and configuration; (2) On-going scientific analysis, including production and maintenance of gamma-ray burst, pulsed source and occultation source catalogs, gamma-ray burst spectroscopy, studies of the properties of pulsars and black holes, and long-term monitoring of hard x-ray sources; (3) Maintenance and continuous improvement of BATSE instrument response and calibration data bases; (4) Investigation of the use of solid state detectors for eventual application and instrument to perform all sky monitoring of X-Ray and Gamma sources with high sensitivity; and (5) Support of BATSE outreach activities, including seminars, colloquia and World Wide Web pages. The highlights of this efforts can be summarized in the publications and presentation list.

  3. Gamma ray camera

    Science.gov (United States)

    Perez-Mendez, V.

    1997-01-21

    A gamma ray camera is disclosed for detecting rays emanating from a radiation source such as an isotope. The gamma ray camera includes a sensor array formed of a visible light crystal for converting incident gamma rays to a plurality of corresponding visible light photons, and a photosensor array responsive to the visible light photons in order to form an electronic image of the radiation therefrom. The photosensor array is adapted to record an integrated amount of charge proportional to the incident gamma rays closest to it, and includes a transparent metallic layer, photodiode consisting of a p-i-n structure formed on one side of the transparent metallic layer, and comprising an upper p-type layer, an intermediate layer and a lower n-type layer. In the preferred mode, the scintillator crystal is composed essentially of a cesium iodide (CsI) crystal preferably doped with a predetermined amount impurity, and the p-type upper intermediate layers and said n-type layer are essentially composed of hydrogenated amorphous silicon (a-Si:H). The gamma ray camera further includes a collimator interposed between the radiation source and the sensor array, and a readout circuit formed on one side of the photosensor array. 6 figs.

  4. Gamma ray camera

    Science.gov (United States)

    Perez-Mendez, Victor

    1997-01-01

    A gamma ray camera for detecting rays emanating from a radiation source such as an isotope. The gamma ray camera includes a sensor array formed of a visible light crystal for converting incident gamma rays to a plurality of corresponding visible light photons, and a photosensor array responsive to the visible light photons in order to form an electronic image of the radiation therefrom. The photosensor array is adapted to record an integrated amount of charge proportional to the incident gamma rays closest to it, and includes a transparent metallic layer, photodiode consisting of a p-i-n structure formed on one side of the transparent metallic layer, and comprising an upper p-type layer, an intermediate layer and a lower n-type layer. In the preferred mode, the scintillator crystal is composed essentially of a cesium iodide (CsI) crystal preferably doped with a predetermined amount impurity, and the p-type upper intermediate layers and said n-type layer are essentially composed of hydrogenated amorphous silicon (a-Si:H). The gamma ray camera further includes a collimator interposed between the radiation source and the sensor array, and a readout circuit formed on one side of the photosensor array.

  5. A stochastic model of cascades in 2D turbulence

    CERN Document Server

    Ditlevsen, Peter D

    2012-01-01

    The dual cascade of energy and enstrophy in 2D turbulence cannot easily be understood in terms of an analog to the Richardson-Kolmogorov scenario describing the energy cascade in 3D turbulence. The coherent up- and downscale fluxes points to non-locality of interactions in spectral space, and thus the specific spatial structure of the flow could be important. Shell models, which lack spacial structure and have only local interactions in spectral space, indeed fail in reproducing the correct scaling for the inverse cascade of energy. In order to exclude the possibility that non-locality of interactions in spectral space is crucial for the dual cascade, we introduce a stochastic spectral model of the cascades which is local in spectral space and which shows the correct scaling for both the direct enstrophy - and the inverse energy cascade.

  6. Photonic crystal slab quantum cascade detector

    Energy Technology Data Exchange (ETDEWEB)

    Reininger, Peter, E-mail: peter.reininger@tuwien.ac.at; Schwarz, Benedikt; Harrer, Andreas; Zederbauer, Tobias; Detz, Hermann; Maxwell Andrews, Aaron; Gansch, Roman; Schrenk, Werner; Strasser, Gottfried [Institute for Solid State Electronics and Center for Micro- and Nanostructures, Vienna University of Technology, Floragasse 7, Vienna 1040 (Austria)

    2013-12-09

    In this Letter, we demonstrate the design, fabrication, and characterization of a photonic crystal slab quantum cascade detector (PCS-QCD). By employing a specifically designed resonant cavity, the performance of the photodetector is improved in three distinct ways. The PCS makes the QCD sensitive to surface normal incident light. It resonantly enhances the photon lifetime inside the active zone, thus increasing the photocurrent significantly. And, the construction form of the device inherently decreases the noise. Finally, we compare the characteristics of the PCS-QCD to a PCS - quantum well infrared photodetector and outline the advantages for certain fields of applications.

  7. Cascaded uncoupled dual-ring modulator

    CERN Document Server

    Gu, Tingyi; Wong, Chee Wei; Dong, Po

    2014-01-01

    We demonstrate that by coherent driving two uncoupled rings in same direction, the effective photon circulating time in the dual ring modulator is reduced, with increased modulation quality. The inter-ring detuning dependent photon dynamics, Q-factor, extinction ratio and optical modulation amplitude of two cascaded silicon ring resonators are studied and compared with that of a single ring modulator. Experimentally measured eye diagrams, together with coupled mode theory simulations, demonstrate the enhancement of dual ring configuration at 20 Gbps with a Q ~ 20,000.

  8. Tracking Control for Switched Cascade Nonlinear Systems

    Directory of Open Access Journals (Sweden)

    Xiaoxiao Dong

    2015-01-01

    Full Text Available The issue of H∞ output tracking for switched cascade nonlinear systems is discussed in this paper, where not all the linear parts of subsystems are stabilizable. The conditions of the solvability for the issue are given by virtue of the structural characteristics of the systems and the average dwell time method, in which the total activation time for stabilizable subsystems is longer than that for the unstabilizable subsystems. At last, a simulation example is used to demonstrate the validity and advantages of the proposed approach.

  9. The identification of a cascade hypernucleus

    CERN Document Server

    Mondal, A S; Husain, A; Kasim, M M

    1979-01-01

    In a systematic search for rare hypernuclear species in nuclear emulsion exposed to 3.0 GeV/c K/sup -/-mesons at the CERN PS, an event with three connecting stars has been observed. The two secondary stars are most probably due to the decay of a cascade hypernucleus according to the following channel: /sub Xi //sup -13/-C to /sub Lambda //sup 8 /Be+/sub Lambda //sup 5/He+Q. The binding energy of the Xi - hypernucleus is B/sub Xi /-(/sub Xi //sup 13/-C)=(18.1+or-3.2) MeV. (11 refs).

  10. Plant MAPK cascades: Just rapid signaling modules?

    KAUST Repository

    Boudsocq, Marie

    2015-08-27

    © 2015 Taylor & Francis Group, LLC. Abscisic acid (ABA) is a major phytohormone mediating important stress-related processes. We recently unveiled an ABA-activated MAPK signaling module constituted of MAP3K17/18-MKK3-MPK1/2/7/14. Unlike classical rapid MAPK activation, we showed that the activation of the new MAPK module is delayed and relies on the MAP3K protein synthesis. In this addendum, we discuss the role of this original and unexpected activation mechanism of MAPK cascades which suggests that MAPKs can regulate both early and longterm plant stress responses.

  11. Direct and inverse cascades in the geodynamo

    CERN Document Server

    Reshetnyak, M

    2010-01-01

    The rapid rotation of planets causes cyclonic thermal turbulence in their cores which may generate the large-scale magnetic fields observed outside the planets. We consider the model which enables us reproduce the typical features of small-scale geostrophic flows in physical and wave spaces. We present estimates of kinetic and magnetic energy fluxes as a function of the wave number. The joint existence of forward and inverse cascades are demonstrated. We also consider the mechanism of magnetic field saturation at the end of the kinematic dynamo regime.

  12. Beam combining of quantum cascade laser arrays.

    Science.gov (United States)

    Lee, Benjamin G; Kansky, Jan; Goyal, Anish K; Pflügl, Christian; Diehl, Laurent; Belkin, Mikhail A; Sanchez, Antonio; Capasso, Federico A

    2009-08-31

    Wavelength beam combining was used to co-propagate beams from 28 elements in an array of distributed-feedback quantum cascade lasers (DFB-QCLs). The beam-quality product of the array, defined as the product of near-field spot size and far-field divergence for the entire array, was improved by a factor of 21 by using wavelength beam combining. To demonstrate the applicability of wavelength beam combined DFB-QCL arrays for remote sensing, we obtained the absorption spectrum of isopropanol at a distance of 6 m from the laser array.

  13. Multiplier phenomenology in random multiplicative cascade processes

    CERN Document Server

    Jouault, B; Greiner, M; Jouault, Bruno; Lipa, Peter; Greiner, Martin

    1999-01-01

    We demonstrate that the correlations observed in conditioned multiplier distributions of the energy dissipation in fully developed turbulence can be understood as an unavoidable artefact of the observation procedure. Taking the latter into account, all reported properties of both unconditioned and conditioned multiplier distributions can be reproduced by cascade models with uncorrelated random weights if their bivariate splitting function is non-energy conserving. For the alpha-model we show that the simulated multiplier distributions converge to a limiting form, which is very close to the experimentally observed one. If random translations of the observation window are accounted for, also the subtle effects found in conditioned multiplier distributions are precisely reproduced.

  14. Cascading Multicriticality in Nonrelativistic Spontaneous Symmetry Breaking

    CERN Document Server

    Griffin, Tom; Horava, Petr; Yan, Ziqi

    2015-01-01

    Without Lorentz invariance, spontaneous global symmetry breaking can lead to multicritical Nambu-Goldstone modes with a higher-order low-energy dispersion $\\omega\\sim k^n$ ($n=2,3,\\ldots$), whose naturalness is protected by polynomial shift symmetries. Here we investigate the role of infrared divergences and the nonrelativistic generalization of the Coleman-Hohenberg-Mermin-Wagner (CHMW) theorem. We find novel cascading phenomena with large hierarchies between the scales at which the value of $n$ changes, leading to an evasion of the "no-go" consequences of the relativistic CHMW theorem.

  15. Long-Haul TCP vs. Cascaded TCP

    OpenAIRE

    Feng, Wu-chun

    2006-01-01

    In this work, we investigate the bandwidth and transfer time of long-haul TCP versus cascaded TCP [5]. First, we discuss the models for TCP throughput. For TCP flows in support of bulk data transfer (i.e., long-lived TCP flows), the TCP throughput models have been derived [2, 3]. These models rely on the congestion-avoidance algorithm of TCP. Though these models cannot be applied with short-lived TCP connections, our interest relative to logistical networking is in longer-li...

  16. Direct and inverse cascades in the geodynamo

    Directory of Open Access Journals (Sweden)

    M. Reshetnyak

    2008-11-01

    Full Text Available The rapid rotation of planets causes cyclonic thermal turbulence in their cores which may generate the large-scale magnetic fields observed outside the planets. We investigate numerically a model based on the geodynamo equations in simplified geometry, which enables us to reproduce the main features of small-scale geostrophic flows in physical and wave vector spaces. We find fluxes of kinetic and magnetic energy as a function of the wave number and demonstrate the co-existence of forward and inverse cascades. We also explain the mechanism of magnetic field saturation at the end of the kinematic dynamo regime.

  17. Evaluating logic functionality of cascaded fracturable LUTs

    Institute of Scientific and Technical Information of China (English)

    GUO Zhenhong; LIN Yu; LI Tianyi; JIA Rui; GAO Tongqiang; YANG Haigang

    2016-01-01

    Look Up Tables(LUTs) are the key components of Field-Programmable Gate Arrays(FPGAs). Many LUT architectures have been studied; nevertheless, it is difficult to quantificationally evaluate an LUT based architecture. Traditionally, dedicated efforts on specific modifications to the technology mapping tools are required for LUT architecture evaluation. A more feasible evaluation method for logic functionality is strongly required for the design of LUT architecture. In this paper, a mathematical method for logic functionality calculation is proposed and conventional and fracturable LUT architectures are analyzed. Furthermore, a cascaded fracturable LUT architecture is presented, which achieves twice logic functionality compared with the conventional LUTs and fracturable LUTs.

  18. Detecting extended gamma-ray emission with the next generation Cherenkov telescopes

    CERN Document Server

    Alonso, M Fernandez; Rovero, A C

    2015-01-01

    Very high energy (VHE $>$100 GeV) gamma rays coming from blazars can produce pairs when interacting with the Extragalactic Background Light (EBL) and the Cosmic Microwave Background, generating an electromagnetic cascade. Depending on the Intergalactic Magnetic Field (IGMF) intensity, this cascade may result in an extended isotropic emission of photons around the source (halo), or in a broadening of the emission beam. The detection of these effects might lead to important constrains both on the IGMF intensity and the EBL density, quantities of great relevance in cosmological models. Using a Monte Carlo program, we simulate electromagnetic cascades for different values of the IGMF intensities and coming from a source similar to 1ES0229+200, a blazar with hard intrinsic spectrum at redshift $z=0.14$, which is an ideal distance for potentially observing the effect. We study the possible response of a generic future Cherenkov telescope using a simplified model for the sensitivity, effective area and angular resol...

  19. Application of Stereoscopic and Tomographic PIV in a Transonic Cascade

    OpenAIRE

    Klinner, Joachim; Willert, Christian

    2014-01-01

    The contribution demonstrates the applicability of volumetric PIV in a highly loaded compressor cascade at Ma_1 = 0.60. Under these operation conditions the secondary flow structures in the cascade are dominated by a passage vortex located at the base of the blade and near the suction side. The application of volume resolving thick-sheet PIV (or tomo-PIV) near the trailing edge of the cascades blades is intended to demonstrate the techniques potential of instantaneously resolving secondary fl...

  20. Stopping pions in high-energy nuclear cascades.

    Science.gov (United States)

    Jones, W. V.; Johnson, D. P.; Thompson, J. A.

    1973-01-01

    Results of Monte Carlo calculations for the number and energy spectra of charged pions from nuclear-electromagnetic cascades developing in rock are presented for primary hadron energies ranging from 3 to 3000 GeV. These spectra are given as functions of the longitudinal depth in the absorber and the lateral distance from the cascade axis. The number of charged pions which stop in the absorber increases with the primary energy of the hadron initiating the cascade.

  1. Damped trophic cascades driven by fishing in model marine ecosystems

    DEFF Research Database (Denmark)

    Andersen, Ken Haste; Pedersen, Martin

    2010-01-01

    that fishing does not change the overall slope of the size spectrum, but depletes the largest individuals and induces trophic cascades. A trophic cascade can propagate both up and down in trophic levels driven by a combination of changes in predation mortality and food limitation. The cascade is damped...... cascade triggered by the removal of top predators. Here we use a novel size- and trait-based model to explore how marine ecosystems might react to perturbations from different types of fishing pressure. The model explicitly resolves the whole life history of fish, from larvae to adults. The results show...

  2. Large-scale separation and hysteresis in cascades

    Science.gov (United States)

    Rothmayer, A. P.; Smith, F. T.

    1985-01-01

    An approach using a two-dimensional thin aerofoil, allied with the theory of viscous bluff-body separation, is used to study the initial cross-over from massive separation to an attached flow in a single-row unstaggered cascade. Analytic solutions are developed for the limit of small cascade-spacing. From the analytic solutions several interesting features of the cascade are examined, including multiple-solution branches and multiple regions of hysteresis. In addition, numerical results are presented for several selected aerofoils. Some of the aerofoils are found to contain markedly enlarged regions of hysteresis for certain critical cascade spacings.

  3. The role of AVDR in linear cascade testing

    Institute of Scientific and Technical Information of China (English)

    Bo Song; Wing F.Ng

    2007-01-01

    Linear cascade testing plays an important role in the research and development of turbomachinery and is widelv used over the world.The ideal cascade model of a turbomachinery blade row is two-dimensional.In actual linear cascade tesring,the flow through the test section converges due to the development of the boundary layer and secondary flow along the sidewall surfaces of the test section.Axial velocity density ratio(AVDR)is adopted to account for the deviation of the tested cascade flow from the ideal 2D model.Among numerous published cascade works,the influence of AVDR on cascade performance is seen to be complicated with many affecting factors,such as those related to cascade/blade geometry and flow conditions.Also,controlling AVDR is limited by the facility capability.Furthermore'real blade-to-blade flow in turborrlachines is usually associated with AVDR greater than unity due to limited span of blades between the hub and shroud such that cascade testing without reducing AVDR could be favored sometimes.All these facets add complexity and diversification to the matter.The current paper reviews previous studies and results on AVDR.ConsoIidated understanding on the role of AVDR and recommendations on how to deal with it in linear cascade testing are provided.

  4. Noise propagation in two-step series MAPK cascade.

    Directory of Open Access Journals (Sweden)

    Venkata Dhananjaneyulu

    Full Text Available Series MAPK enzymatic cascades, ubiquitously found in signaling networks, act as signal amplifiers and play a key role in processing information during signal transduction in cells. In activated cascades, cell-to-cell variability or noise is bound to occur and thereby strongly affects the cellular response. Commonly used linearization method (LM applied to Langevin type stochastic model of the MAPK cascade fails to accurately predict intrinsic noise propagation in the cascade. We prove this by using extensive stochastic simulations for various ranges of biochemical parameters. This failure is due to the fact that the LM ignores the nonlinear effects on the noise. However, LM provides a good estimate of the extrinsic noise propagation. We show that the correct estimate of intrinsic noise propagation in signaling networks that contain at least one enzymatic step can be obtained only through stochastic simulations. Noise propagation in the cascade depends on the underlying biochemical parameters which are often unavailable. Based on a combination of global sensitivity analysis (GSA and stochastic simulations, we developed a systematic methodology to characterize noise propagation in the cascade. GSA predicts that noise propagation in MAPK cascade is sensitive to the total number of upstream enzyme molecules and the total number of molecules of the two substrates involved in the cascade. We argue that the general systematic approach proposed and demonstrated on MAPK cascade must accompany noise propagation studies in biological networks.

  5. SVOM gamma ray monitor

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The space-based multi-band astronomical Variable Object Monitor(SVOM) mission is dedicated to the detection,localization and broad-band study of gamma-ray bursts(GRBs) and other high-energy transient phenomena.The gamma ray monitor(GRM) onboard is designed to observe GRBs up to 5 MeV.With this instrument,one of the key GRB parameters,Epeak,can be easily measured in the hard X-ray band.It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM.

  6. SVOM Gamma Ray Monitor

    CERN Document Server

    Dong, Yongwei; Li, Yanguo; Zhang, Yongjie; Zhang, Shuangnan

    2009-01-01

    The Space-based multi-band astronomical Variable Object Monitor (SVOM) mission is dedicated to the detection, localization and broad-band study of Gamma-Ray Bursts (GRBs) and other high-energy transient phenomena. The Gamma Ray Monitor (GRM) onboard is designed to observe the GRBs up to 5 MeV. With this instrument one of the key GRB parameter, Epeak, can be easily measured in the hard x-ray band. It can achieve a detection rate of 100 GRBs per year which ensures the scientific output of SVOM.

  7. Nonlinear modeling of thermoacoustically driven energy cascade

    Science.gov (United States)

    Gupta, Prateek; Scalo, Carlo; Lodato, Guido

    2016-11-01

    We present an investigation of nonlinear energy cascade in thermoacoustically driven high-amplitude oscillations, from the initial weakly nonlinear regime to the shock wave dominated limit cycle. We develop a first principle based quasi-1D model for nonlinear wave propagation in a canonical minimal unit thermoacoustic device inspired by the experimental setup of Biwa et al.. Retaining up to quadratic nonlinear terms in the governing equations, we develop model equations for nonlinear wave propagation in the proximity of differentially heated no-slip boundaries. Furthermore, we discard the effects of acoustic streaming in the present study and focus on nonlinear energy cascade due to high amplitude wave propagation. Our model correctly predicts the observed exponential growth of the thermoacoustically amplified second harmonic, as well as the energy transfer rate to higher harmonics causing wave steepening. Moreover, we note that nonlinear coupling of local pressure with heat transfer reduces thermoacoustic amplification gradually thus causing the system to reach limit cycle exhibiting shock waves. Throughout, we verify the results from the quasi-1D model with fully compressible Navier-Stokes simulations.

  8. High efficiency quantum cascade laser frequency comb

    Science.gov (United States)

    Lu, Quanyong; Wu, Donghai; Slivken, Steven; Razeghi, Manijeh

    2017-01-01

    An efficient mid-infrared frequency comb source is of great interest to high speed, high resolution spectroscopy and metrology. Here we demonstrate a mid-IR quantum cascade laser frequency comb with a high power output and narrow beatnote linewidth at room temperature. The active region was designed with a strong-coupling between the injector and the upper lasing level for high internal quantum efficiency and a broadband gain. The group velocity dispersion was engineered for efficient, broadband mode-locking via four wave mixing. The comb device exhibits a narrow intermode beatnote linewidth of 50.5 Hz and a maximum wall-plug efficiency of 6.5% covering a spectral coverage of 110 cm−1 at λ ~ 8 μm. The efficiency is improved by a factor of 6 compared with previous demonstrations. The high power efficiency and narrow beatnote linewidth will greatly expand the applications of quantum cascade laser frequency combs including high-precision remote sensing and spectroscopy. PMID:28262834

  9. Quantitative analysis of cascade impactor samples - revisited

    Science.gov (United States)

    Orlić , I.; Chiam, S. Y.; Sanchez, J. L.; Tang, S. M.

    1999-04-01

    Concentrations of aerosols collected in Singapore during the three months long haze period that affected the whole South-East Asian region in 1997 are reported. Aerosol samples were continuously collected by using a fine aerosol sampler (PM2.5) and occasionally with a single orifice cascade impactor (CI) sampler. Our results show that in the fine fraction (<2.5 μm) the concentrations of two well-known biomass burning products, i.e. K and S were generally increased by a factor 2-3 compared to the non-hazy periods. However, a discrepancy was noticed, at least for elements with lower atomic number (Ti and below) between the results obtained by the fine aerosol sampler and the cascade impactor. Careful analysis by means of Nuclear Microscopy, in particular by the Scanning Transmission Ion Microscopy (STIM) technique, revealed that thicknesses of the lower CI stages exceeded thick target limits for 2 MeV protons. Detailed depth profiles of all CI stages were therefore measured using the STIM technique and concentrations corrected for absorption and proton energy loss. After correcting results for the actual sample thickness, concentrations of all major elements (S, Cl, K, Ca) agreed much better with the PM2.5 results. The importance of implementing thick target corrections in analysis of CI samples, especially those collected in the urban environments, is emphasized. Broad beam PIXE analysis approach is certainly not adequate in these cases.

  10. Frequency division using a micromechanical resonance cascade

    Energy Technology Data Exchange (ETDEWEB)

    Qalandar, K. R., E-mail: kamala@engineering.ucsb.edu; Gibson, B.; Sharma, M.; Ma, A.; Turner, K. L. [Department of Mechanical Engineering, University of California at Santa Barbara, Santa Barbara, California 93106 (United States); Strachan, B. S. [Department of Mechanical Engineering, Michigan State University, East Lansing, Michigan 48823 (United States); Department of Electrical Engineering, Michigan State University, East Lansing, Michigan 48823 (United States); Shaw, S. W. [Department of Mechanical Engineering, Michigan State University, East Lansing, Michigan 48823 (United States); Department of Physics and Astronomy, Michigan State University, East Lansing, Michigan 48823 (United States)

    2014-12-15

    A coupled micromechanical resonator array demonstrates a mechanical realization of multi-stage frequency division. The mechanical structure consists of a set of N sequentially perpendicular microbeams that are connected by relatively weak elastic elements such that the system vibration modes are localized to individual microbeams and have natural frequencies with ratios close to 1:2:⋯:2{sup N}. Conservative (passive) nonlinear inter-modal coupling provides the required energy transfer between modes and is achieved by finite deformation kinematics. When the highest frequency beam is excited, this arrangement promotes a cascade of subharmonic resonances that achieve frequency division of 2{sup j} at microbeam j for j = 1, …, N. Results are shown for a capacitively driven three-stage divider in which an input signal of 824 kHz is passively divided through three modal stages, producing signals at 412 kHz, 206 kHz, and 103 kHz. The system modes are characterized and used to delineate the range of AC input voltages and frequencies over which the cascade occurs. This narrow band frequency divider has simple design rules that are scalable to higher frequencies and can be extended to a larger number of modal stages.

  11. High efficiency quantum cascade laser frequency comb

    Science.gov (United States)

    Lu, Quanyong; Wu, Donghai; Slivken, Steven; Razeghi, Manijeh

    2017-03-01

    An efficient mid-infrared frequency comb source is of great interest to high speed, high resolution spectroscopy and metrology. Here we demonstrate a mid-IR quantum cascade laser frequency comb with a high power output and narrow beatnote linewidth at room temperature. The active region was designed with a strong-coupling between the injector and the upper lasing level for high internal quantum efficiency and a broadband gain. The group velocity dispersion was engineered for efficient, broadband mode-locking via four wave mixing. The comb device exhibits a narrow intermode beatnote linewidth of 50.5 Hz and a maximum wall-plug efficiency of 6.5% covering a spectral coverage of 110 cm‑1 at λ ~ 8 μm. The efficiency is improved by a factor of 6 compared with previous demonstrations. The high power efficiency and narrow beatnote linewidth will greatly expand the applications of quantum cascade laser frequency combs including high-precision remote sensing and spectroscopy.

  12. Cascades and perturbed Morse-Bott functions

    CERN Document Server

    Banyaga, Augustin

    2011-01-01

    Let $f:M \\rightarrow \\mathbb{R}$ be a Morse-Bott function on a finite dimensional closed smooth manifold $M$. Choosing an appropriate Riemannian metric on $M$ and Morse-Smale functions $f_j:C_j \\rightarrow \\mathbb{R}$ on the critical submanifolds $C_j$, one can construct a Morse chain complex whose boundary operator is defined by counting cascades \\cite{FraTheA}. Similar data, which also includes a parameter $\\epsilon > 0$ that scales the Morse-Smale functions $f_j$, can be used to define an explicit perturbation of the Morse-Bott function $f$ to a Morse-Smale function $h_\\epsilon:M \\rightarrow \\mathbb{R}$ \\cite{AusMor} \\cite{BanDyn}. In this paper we show that the Morse-Smale-Witten chain complex of $h_\\epsilon$ is the same as the Morse chain complex defined using cascades for any $\\epsilon >0$ sufficiently small. That is, the two chain complexes have the same generators, and their boundary operators are the same (up to a choice of sign). Thus, the Morse Homology Theorem implies that the homology of the casc...

  13. The Cascade is a MMS Instanton

    CERN Document Server

    Evslin, J

    2004-01-01

    Wrap m D5-branes around the 2-cycle of a conifold, place n D3-branes at a point and watch the system relax. The D5-branes source m units of RR 3-form flux on the 3-cycle, which cause dielectric NS5-branes to nucleate and repeatedly sweep out the 3-cycle, each time gaining m units of D3-charge while the stack of D5-branes loses m units of D3-charge. A similar description of the Klebanov-Strassler cascade has been proposed by Kachru, et al. when m>>m-n. Using the T-dual MQCD we argue that the above process occurs for any m and n and in particular may continue for more than one step. The nonbaryonic roots of the SQCD vacua lead to new cascades because, for example, the 3-cycle swept does not link all of the D5's. This decay is the S-dual of a MMS instanton, which is the decay into flux of a brane that is trivial in twisted K-theory. This provides the first evidence for the S-dual of the K-theory classification that does not itself rely upon any strong/weak duality.

  14. Power Grid Defense Against Malicious Cascading Failure

    CERN Document Server

    Shakarian, Paulo; Lindelauf, Roy

    2014-01-01

    An adversary looking to disrupt a power grid may look to target certain substations and sources of power generation to initiate a cascading failure that maximizes the number of customers without electricity. This is particularly an important concern when the enemy has the capability to launch cyber-attacks as practical concerns (i.e. avoiding disruption of service, presence of legacy systems, etc.) may hinder security. Hence, a defender can harden the security posture at certain power stations but may lack the time and resources to do this for the entire power grid. We model a power grid as a graph and introduce the cascading failure game in which both the defender and attacker choose a subset of power stations such as to minimize (maximize) the number of consumers having access to producers of power. We formalize problems for identifying both mixed and deterministic strategies for both players, prove complexity results under a variety of different scenarios, identify tractable cases, and develop algorithms f...

  15. Establishment of M1 multipolarity of a 6.5 mu_N^2 resonance in 172-Yb at E_gamma=3.3 MeV

    CERN Document Server

    Schiller, A; Algin, E; Becker, J A; Bernstein, L A; Garrett, P E; Guttormsen, M; Nelson, R O; Rekstad, J; Siem, S

    2004-01-01

    Two-step-cascade spectra in 172-Yb have been measured after thermal neutron capture. They are compared to calculations based on experimental values of the level density and radiative strength function (RSF) obtained from the 173-Yb(3-He,alpha gamma)172-Yb reaction. The multipolarity of a 6.5(15) mu_N^2 resonance at E_gamma=3.3(1) MeV in the RSF is determined to be M1 by this comparison.

  16. Quaternary Magmatism in the Cascades - Geologic Perspectives

    Science.gov (United States)

    Hildreth, Wes

    2007-01-01

    Foreward The Cascade magmatic arc is a belt of Quaternary volcanoes that extends 1,250 km from Lassen Peak in northern California to Meager Mountain in Canada, above the subduction zone where the Juan de Fuca Plate plunges beneath the North American Plate. This Professional Paper presents a synthesis of the entire volcanic arc, addressing all 2,300 known Quaternary volcanoes, not just the 30 or so visually prominent peaks that comprise the volcanic skyline. Study of Cascade volcanoes goes back to the geological explorers of the late 19th century and the seminal investigations of Howel Williams in the 1920s and 1930s. However, major progress and application of modern scientific methods and instrumentation began only in the 1970s with the advent of systematic geological, geophysical, and geochemical studies of the entire arc. Initial stimulus from the USGS Geothermal Research Program was enhanced by the USGS Volcano Hazards Program following the 1980 eruption of Mount St. Helens. Together, these two USGS Programs have provided more than three decades of stable funding, staffing, and analytical support. This Professional Paper summarizes the resultant USGS data sets and integrates them with the parallel contributions of other investigators. The product is based upon an all-encompassing and definitive geological database, including chemical and isotopic analyses to characterize the rocks and geochronology to provide the critical time constraints. Until now, this massive amount of data has not been summarized, and a systematic and uniform interpretation firmly grounded in geological fact has been lacking. Herein lies the primary utility of this Cascade volume. It not only will be the mandatory starting point for new workers, but also will provide essential geological context to broaden the perspectives of current investigators of specific Cascade volcanoes. Wes Hildreth's insightful understanding of volcanic processes and his uncompromising scientific integrity make him

  17. Wsup(+-) boson production at the e/sup +/e/sup -/,. gamma. e and. gamma gamma. colliding beams

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Panfil, S.L.; Serbo, V.G.

    1983-11-21

    Wsup(+-) boson production in e/sup +/e/sup -/->W/sup +/W/sup -/, ..gamma..e->W/sup +/W/sup -/, ..gamma..e->W, ..gamma gamma..->W/sup +/W/sup -/ reactions at the e/sup +/e/sup -/, ..gamma..e and ..gamma gamma.. colliding beams is considered. What physical information can be extracted from such experiments, including those with polarized beams, is discussed. Conditions of observation, are considered together with the background problems.

  18. The Orbis Cascade Merger and Its Impact on Patron-Initiated Borrowing

    Science.gov (United States)

    Munson, Doris M.; Milton, Suzanne

    2009-01-01

    In 2000, Eastern Washington University became part of the Cascade Consortium and participated in consortial borrowing through the Cascade Union Catalog. In 2003, the Orbis and Cascade consortia merged into the Orbis Cascade Alliance, which manages the Summit Union Catalog. Since 2000, Cascade or Summit consortial borrowing has increased while…

  19. Interferon Gamma-1b Injection

    Science.gov (United States)

    Interferon gamma-1b injection is used to reduce the frequency and severity of serious infections in people with ... with severe, malignant osteopetrosis (an inherited bone disease). Interferon gamma-1b is in a class of medications called ...

  20. Gamma knife surgery for craniopharyngioma.

    Science.gov (United States)

    Prasad, D; Steiner, M; Steiner, L

    1995-01-01

    We present our results of Gamma Knife surgery for craniopharyngioma in nine patients. The current status of surgery, radiation therapy, intracavitary instillation of radionucleides and Gamma Knife surgery in the management of craniopharyngiomas is discussed.

  1. CKM angle $\\gamma$ from LHCb

    CERN Multimedia

    Smith, Jackson

    2015-01-01

    Results of the latest $\\gamma$ combination from LHCb are presented, along with the six LHCb measurements used as inputs. In addition, the anticipated precision attainable for measuring $\\gamma$ after the LHCb Upgrade is outlined

  2. Construction of a {gamma}-{gamma} and {beta}-{gamma} coincidence measurement system for precise determination of nuclear data

    Energy Technology Data Exchange (ETDEWEB)

    Furutaka, Kazuyoshi; Nakamura, Shoji; Harada, Hideo; Katoh, Toshio [Japan Nuclear Cycle Development Institute, Tokai Works, Tokai, Ibaraki (Japan)

    1999-03-01

    A {gamma}-{gamma} and {beta}-{gamma} coincidence measurement system was constructed for the precise determination of nuclear data, such as thermal neutron capture cross sections and {gamma}-ray emission probabilities. The validity of the system was tested by a {gamma}-{gamma} coincidence measurement with a {sup 60}Co standard source. (author)

  3. Gamma rays from Galactic pulsars

    OpenAIRE

    2014-01-01

    Gamma rays from young pulsars and milli-second pulsars are expected to contribute to the diffuse gamma-ray emission measured by the {\\it Fermi} Large Area Telescope (LAT) at high latitudes. We derive the contribution of the pulsars undetected counterpart by using information from radio to gamma rays and we show that they explain only a small fraction of the isotropic diffuse gamma-ray background.

  4. A 2.5 kW cascaded Schwarz converter for 20 kHz power distribution

    Science.gov (United States)

    Shetler, Russell E.; Stuart, Thomas A.

    Because it avoids the high currents in a parallel loaded capacitor, the cascaded Schwarz converter should offer better component utilization than converters with sinusoidal output voltages. The circuit is relatively easy to protect, and it provides a predictable trapezoidal voltage waveform that should be satisfactory for 20-kHz distribution systems. Analysis of the system is enhanced by plotting curves of normalized variables vs. gamma(1), where gamma(1) is proportional to the variable frequency of the first stage. Light-load operation is greatly improved by the addition of a power recycling rectifier bridge that is back biased at medium to heavy loads. Operation has been verified on a 2.5-kW circuit that uses input and output voltages in the same range as those anticipated for certain future spacecraft power systems.

  5. A 2.5 kW cascaded Schwarz converter for 20 kHz power distribution

    Science.gov (United States)

    Shetler, Russell E.; Stuart, Thomas A.

    1989-01-01

    Because it avoids the high currents in a parallel loaded capacitor, the cascaded Schwarz converter should offer better component utilization than converters with sinusoidal output voltages. The circuit is relatively easy to protect, and it provides a predictable trapezoidal voltage waveform that should be satisfactory for 20-kHz distribution systems. Analysis of the system is enhanced by plotting curves of normalized variables vs. gamma(1), where gamma(1) is proportional to the variable frequency of the first stage. Light-load operation is greatly improved by the addition of a power recycling rectifier bridge that is back biased at medium to heavy loads. Operation has been verified on a 2.5-kW circuit that uses input and output voltages in the same range as those anticipated for certain future spacecraft power systems.

  6. The shifting gamma perception

    NARCIS (Netherlands)

    Besuijen, J.

    2005-01-01

    True to life, color display and color management depend on a proper technical model of the display used. Current gamma models and fitting procedures are not accurate in modeling the lower part of the tone reproduction curve. The GOG- and GOGO-model used in color management standards tend to clip the

  7. Proprioceptive evoked gamma oscillations

    DEFF Research Database (Denmark)

    Arnfred, Sidse M; Hansen, Lars Kai; Parnas, Josef;

    2007-01-01

    A proprioceptive stimulus consisting of a weight change of a handheld load has recently been shown to elicit an evoked potential. Previously, somatosensory gamma oscillations have only been evoked by electrical stimuli. We conjectured that a natural proprioceptive stimulus also would be able...

  8. Proprioceptive evoked gamma oscillations

    DEFF Research Database (Denmark)

    Arnfred, S.M.; Hansen, Lars Kai; Parnas, J.;

    2007-01-01

    to evoke gamma oscillations. EEG was recorded using 64 channels in 14 healthy subjects. In each of three runs a stimulus of 100 g load increment in each hand was presented in 120 trials. Data were wavelet transformed and runs collapsed. Inter-trial phase coherence (ITPC) was computed as the best measure...

  9. Measurement of {\\eta} meson production in {\\gamma}{\\gamma} interactions and {\\Gamma}({\\eta}-->{\\gamma}{\\gamma}) with the KLOE detector

    CERN Document Server

    :,; Badoni, D; Balwierz-Pytko, I; Bencivenni, G; Bini, C; Bloise, C; Bossi, F; Branchini, P; Budano, A; Balkestaahl, L Caldeira; Capon, G; Ceradini, F; Ciambrone, P; Czerwinski, E; Dane, E; De Lucia, E; De Robertis, G; De Santis, A; Di Domenico, A; Di Donato, C; Di Salvo, R; Domenici, D; Erriquez, O; Fanizzi, G; Fantini, A; Felici, G; Fiore, S; Franzini, P; Gauzzi, P; Giardina, G; Giovannella, S; Gonnella, F; Graziani, E; Happacher, F; Heijkenskj, L; Hoistad, B; Iafolla, L; Jacewicz, M; Johansson, T; Kupsc, A; Lee-Franzini, J; Leverington, B; Loddo, F; Loffredo, S; Mandaglio, G; Martemianov, M; Martini, M; Mascolo, M; Messi, R; Miscetti, S; Morello, G; Moricciani, D; Moskal, P; Nguyen, F; Passeri, A; Patera, V; Longhi, I Prado; Ranieri, A; Redmer, C F; Santangelo, P; Sarra, I; Schioppa, M; Sciascia, B; Silarski, M; Taccini, C; Tortora, L; Venanzoni, G; Wislicki, W; Wolke, M; Zdebik, J

    2012-01-01

    We present a measurement of {\\eta} meson production in photon-photon interactions produced by electron-positron beams colliding with \\sqrt{s}=1 GeV. The measurement is done with the KLOE detector at the \\phi-factory DA{\\Phi}NE with an integrated luminosity of 0.24 fb^{-1}. The e^+e^- --> e^+e^-{\\eta} cross section is measured without detecting the outgoing electron and positron, selecting the decays {\\eta}-->{\\pi}^+{\\pi}^-{\\pi}^0 and {\\eta}-->{\\pi}^0{\\pi}^0{\\pi}^0. The most relevant background is due to e^+e^- --> {\\eta}{\\gamma} when the monochromatic photon escapes detection. The cross section for this process is measured as {\\sigma}(e^+e^- -->{\\eta}{\\gamma}) = (856 \\pm 8_{stat} \\pm 16_{syst}) pb. The combined result for the e^+e^- -->e^+e^-{\\eta} cross section is {\\sigma}(e^+e^- -->e^+e^-{\\eta}) = (32.72 \\pm 1.27_{stat} \\pm 0.70_{syst}) pb. From this we derive the partial width {\\Gamma}({\\eta}-->{\\gamma}{\\gamma}) = (520 \\pm 20_{stat} \\pm 13_{syst}) eV. This is in agreement with the world average and is the ...

  10. Gamma-ray performance of the GAMMA-400 detector

    CERN Document Server

    Cumani, P; Bonvicini, V; Topchiev, N P; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, S; Bongi, M; Bottai, S; Castellini, G; Cattaneo, P W; Dedenko, G L; De Donato, C; Dogiel, V A; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Leonov, A A; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Menshenin, A L; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Popov, A V; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Sarkar, R; Serdin, O V; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Taraskin, A A; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2015-01-01

    GAMMA-400 is a new space mission, designed as a dual experiment, capable to study both high energy gamma rays (from $\\sim$100 MeV to few TeV) and cosmic rays (electrons up to 20 TeV and nuclei up to $\\sim$10$^{15}$ eV). The full simulation framework of GAMMA-400 is based on the Geant4 toolkit. The details of the gamma-ray reconstruction pipeline in the three main instruments (Tracker, Imaging Calorimeter, Homogeneous Calorimeter) will be outlined. The performance of GAMMA-400 (PSF, effective area and sensitivity) have been obtained using this framework. The most updated results on them will be shown.

  11. Lower Bound on the Cosmic TeV Gamma-ray Background Radiation

    CERN Document Server

    Inoue, Yoshiyuki

    2015-01-01

    The Fermi gamma-ray space telescope has revolutionized our understanding of the cosmic gamma-ray background radiation in the GeV band. However, investigation on the cosmic TeV gamma-ray background radiation still remains sparse. Here, we report the lower bound on the cosmic TeV gamma-ray background spectrum placed by the cumulative flux of individual detected extragalactic TeV sources including blazars, radio galaxies, and starburst galaxies. The current limit on the cosmic TeV gamma-ray background above 0.1 TeV is obtained as $3\\times10^{-8} (E/100~{\\rm GeV})^{-0.6} \\exp(-E/2000~{\\rm GeV})~{\\rm [GeV/cm^2/s/sr]} < E^2dN/dE < 1\\times10^{-7} (E/100~{\\rm GeV})^{-0.5}~{\\rm [GeV/cm^2/s/sr]}$, where the upper bound is set by requirement that the cascade flux from the cosmic TeV gamma-ray background radiation can not exceed the measured cosmic GeV gamma-ray background spectrum (Inoue & Ioka 2012). Two nearby blazars, Mrk 421 and Mrk 501, explain ~70% of the cumulative flux at 0.8-4 TeV, while extreme blaza...

  12. GEANT4 Simulations of Gamma-Gamma Angular Correlations with GRIFFIN

    Science.gov (United States)

    Natzke, Connor; Griffin Collaboration

    2016-09-01

    The structure of very neutron rich isotopes has been of recent experimental interest for both nuclear astrophysics and fundamental nuclear structure investigations. In beta-minus decay specifically, beta-delayed gamma cascades can help to shed light on the spin and parity of the states involved. One of the world's most powerful decay spectroscopy tool is the Gamma-Ray Infrastructure For Fundamental Investigations of Nuclei (GRIFFIN) spectrometer at TRIUMF-ISAC in Vancouver, Canada. To investigate the feasibility of these experimental studies, GEANT4 simulations of neutron-rich nuclei are critical, as they are able to provide realistic estimates of what the experimental results may look like. The first such nucleus investigated was 44P, and both the temporal and angular γγ correlations were extracted. Furthermore the simulations were used to model various multipole decay possibilities which provide a powerful tool analyzing collected data from such facilities. In the future, the Facility for Rare Isotope Beams (FRIB) at MSU will be an ideal site for such studies on the most exotic nuclei.

  13. 36 CFR 7.66 - North Cascades National Park.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false North Cascades National Park. 7.66 Section 7.66 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SPECIAL REGULATIONS, AREAS OF THE NATIONAL PARK SYSTEM § 7.66 North Cascades National Park....

  14. Signaling Cascades: Consequences of Varying Substrate and Phosphatase Levels

    DEFF Research Database (Denmark)

    Feliu, Elisenda; Knudsen, Michael; Wiuf, Carsten Henrik

    2012-01-01

    We study signaling cascades with an arbitrary number of layers of one-site phosphorylation cycles. Such cascades are abundant in nature and integrated parts of many pathways. Based on the Michaelis-Menten model of enzyme kinetics and the law of mass-action, we derive explicit analytic expressions...

  15. Cascade algorithm and multiresolution analysis on the Heisenberg group

    Institute of Scientific and Technical Information of China (English)

    LIU Heping; LIU Yu; PENG Lizhong; CHU Xiaoyong

    2005-01-01

    In this paper we investigate the relationship between the convergence of cascade algorithm and orthogonal (or biorthogonal) multiresolution analysis on the Heisenberg group. It is proved that the (strong) convergence of cascade algorithm together with the perfect reconstruction condition induces an orthogonal multiresolution analysis and vice versa. Similar results are also proved for biorthogonal multiresolution analysis.

  16. Cascade vulnerability for risk analysis of water infrastructure.

    Science.gov (United States)

    Sitzenfrei, R; Mair, M; Möderl, M; Rauch, W

    2011-01-01

    One of the major tasks in urban water management is failure-free operation for at least most of the time. Accordingly, the reliability of the network systems in urban water management has a crucial role. The failure of a component in these systems impacts potable water distribution and urban drainage. Therefore, water distribution and urban drainage systems are categorized as critical infrastructure. Vulnerability is the degree to which a system is likely to experience harm induced by perturbation or stress. However, for risk assessment, we usually assume that events and failures are singular and independent, i.e. several simultaneous events and cascading events are unconsidered. Although failures can be causally linked, a simultaneous consideration in risk analysis is hardly considered. To close this gap, this work introduces the term cascade vulnerability for water infrastructure. Cascade vulnerability accounts for cascading and simultaneous events. Following this definition, cascade risk maps are a merger of hazard and cascade vulnerability maps. In this work cascade vulnerability maps for water distribution systems and urban drainage systems based on the 'Achilles-Approach' are introduced and discussed. It is shown, that neglecting cascading effects results in significant underestimation of risk scenarios.

  17. Intermittent Flow Regimes in a Transonic Fan Airfoil Cascade

    Directory of Open Access Journals (Sweden)

    J. Lepicovsky

    2004-01-01

    velocity.To date, this flow behavior has only been observed in a linear transonic cascade. Further research is necessary to confirm this phenomenon occurs in actual transonic fans and is not the by-product of an endwall restricted linear cascade.

  18. A simple model of global cascades on random networks

    Science.gov (United States)

    Watts, Duncan J.

    2002-04-01

    The origin of large but rare cascades that are triggered by small initial shocks is a phenomenon that manifests itself as diversely as cultural fads, collective action, the diffusion of norms and innovations, and cascading failures in infrastructure and organizational networks. This paper presents a possible explanation of this phenomenon in terms of a sparse, random network of interacting agents whose decisions are determined by the actions of their neighbors according to a simple threshold rule. Two regimes are identified in which the network is susceptible to very large cascadesherein called global cascadesthat occur very rarely. When cascade propagation is limited by the connectivity of the network, a power law distribution of cascade sizes is observed, analogous to the cluster size distribution in standard percolation theory and avalanches in self-organized criticality. But when the network is highly connected, cascade propagation is limited instead by the local stability of the nodes themselves, and the size distribution of cascades is bimodal, implying a more extreme kind of instability that is correspondingly harder to anticipate. In the first regime, where the distribution of network neighbors is highly skewed, it is found that the most connected nodes are far more likely than average nodes to trigger cascades, but not in the second regime. Finally, it is shown that heterogeneity plays an ambiguous role in determining a system's stability: increasingly heterogeneous thresholds make the system more vulnerable to global cascades; but an increasingly heterogeneous degree distribution makes it less vulnerable.

  19. Influence of blood flow on the coagulation cascade

    DEFF Research Database (Denmark)

    The influence of diffusion and convetive flows on the blood coagulation cascade is investigated for a controlled perfusion experiment. We present a cartoon model and reaction schemes for parts of the coagulation cascade with sunsequent set up of a mathematical model in two space dimensions plus one...

  20. Impedance Coordinative Control for Cascaded Converter in Bidirectional Application

    DEFF Research Database (Denmark)

    Tian, Yanjun; Deng, Fujin; Chen, Zhe;

    2015-01-01

    difference between forward and reversed power flow. This paper addresses the analysis with the topology of cascaded dual-active-bridge converter (DAB) with inverter, and the proposed control method can also be implemented in unidirectional applications and other general cascaded converter system...

  1. Temporal switching induced by cascaded third order nonlinearity

    DEFF Research Database (Denmark)

    Eilenberger, Falk; Bache, Morten; Minardi, Stefano;

    2012-01-01

    We investigate the impact of cascaded third harmonic generation and the intrinsic n4 material nonlinearity on the propagation of ultrashort pulses in noble-gas filled Kagome fibers. We show that the pressure tunability of the cascade allows for the implementation of temporal switching. We also...

  2. RECONFIGURING POWER SYSTEMS TO MINIMIZE CASCADING FAILURES: MODELS AND ALGORITHMS

    Energy Technology Data Exchange (ETDEWEB)

    Bienstock, Daniel

    2014-04-11

    the main goal of this project was to develop new scientific tools, based on optimization techniques, with the purpose of controlling and modeling cascading failures of electrical power transmission systems. We have developed a high-quality tool for simulating cascading failures. The problem of how to control a cascade was addressed, with the aim of stopping the cascade with a minimum of load lost. Yet another aspect of cascade is the investigation of which events would trigger a cascade, or more appropriately the computation of the most harmful initiating event given some constraint on the severity of the event. One common feature of the cascade models described (indeed, of several of the cascade models found in the literature) is that we study thermally-induced line tripping. We have produced a study that accounts for exogenous randomness (e.g. wind and ambient temperature) that could affect the thermal behavior of a line, with a focus on controlling the power flow of the line while maintaining safe probability of line overload. This was done by means of a rigorous analysis of a stochastic version of the heat equation. we incorporated a model of randomness in the behavior of wind power output; again modeling an OPF-like problem that uses chance-constraints to maintain low probability of line overloads; this work has been continued so as to account for generator dynamics as well.

  3. Hadron cascade by the method of characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Tsui, K.H.; Portella, H.M.; Navia, C.E.; Shigueoka, H. [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Inst. de Fisica]. E-mails: tsui@if.uff.br; hmport@if.uff.br; gficnoj@if.uff.br; hisa@if.uff.br; Oliveira, L.C.S. de [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil)]. E-mail: oliveira@cbpf.br

    2005-02-01

    Hadron diffusion equations with energy-dependent interaction mean free paths and inelasticities are solved using the Mellin transform. Instead of using operators on the finite difference terms, the Mellin transformed equations are Taylor expanded into a first order partial differential equation in atmospheric depth t and in the transform parameter s. Then, these equations are solved by the method of residues. For the case of a regularized power law primary spectrum these hadron fluxes are given by simple residues and one, never before mentioned, essential singularities. A comparison of our solutions with the nucleon flux measured at sea level and with the hadron fluxes measured at t = 840 g/cm{sup 2} and at sea level are made. The agreement between them is in general very good, greater than 90%. In order to check the accuracy of our calculations, a comparison between our solution and the simulated nucleon cascades is also made. (author)

  4. Novel trophic cascades: apex predators enable coexistence.

    Science.gov (United States)

    Wallach, Arian D; Ripple, William J; Carroll, Scott P

    2015-03-01

    Novel assemblages of native and introduced species characterize a growing proportion of ecosystems worldwide. Some introduced species have contributed to extinctions, even extinction waves, spurring widespread efforts to eradicate or control them. We propose that trophic cascade theory offers insights into why introduced species sometimes become harmful, but in other cases stably coexist with natives and offer net benefits. Large predators commonly limit populations of potentially irruptive prey and mesopredators, both native and introduced. This top-down force influences a wide range of ecosystem processes that often enhance biodiversity. We argue that many species, regardless of their origin or priors, are allies for the retention and restoration of biodiversity in top-down regulated ecosystems.

  5. Exact coherent structures for the turbulent cascade

    Science.gov (United States)

    Eckhardt, Bruno; Zammert, Stefan

    2016-11-01

    The exact coherent structures that are connected with the transition to turbulence in interior flows usually extend across the full height of the domain. Using exact coherent states that are localized in the shear direction together with scaling ideas for the Navier-Stokes equation that combine length and Reynolds number, we show how such large scale structures can be morphed into smaller scale coherent structures. As the Reynolds number increases, more of these states with ever smaller scales appear, all the way down to the Kolmogorov scale. We present the structure and dynamical properties of several families of exact coherent solution in plane Couette flow, with different degrees of spatial localization: Some of them remain localized in the center and help to built the turbulence cascade, others are localized near the walls and contribute to shaping the boundary layer profile.

  6. Mechanical gating of a mechanochemical reaction cascade

    Science.gov (United States)

    Wang, Junpeng; Kouznetsova, Tatiana B.; Boulatov, Roman; Craig, Stephen L.

    2016-11-01

    Covalent polymer mechanochemistry offers promising opportunities for the control and engineering of reactivity. To date, covalent mechanochemistry has largely been limited to individual reactions, but it also presents potential for intricate reaction systems and feedback loops. Here we report a molecular architecture, in which a cyclobutane mechanophore functions as a gate to regulate the activation of a second mechanophore, dichlorocyclopropane, resulting in a mechanochemical cascade reaction. Single-molecule force spectroscopy, pulsed ultrasonication experiments and DFT-level calculations support gating and indicate that extra force of >0.5 nN needs to be applied to a polymer of gated gDCC than of free gDCC for the mechanochemical isomerization gDCC to proceed at equal rate. The gating concept provides a mechanism by which to regulate stress-responsive behaviours, such as load-strengthening and mechanochromism, in future materials designs.

  7. Electrical derivative measurement of quantum cascade lasers

    Science.gov (United States)

    Guo, Dingkai; Cheng, Liwei; Chen, Xing; Choa, Fow-Sen; Fan, Jenyu; Worchesky, Terry

    2011-02-01

    The electrical derivative characteristics of quantum cascade lasers (QCLs) are investigated to test the QCL threshold, leakage current, and possibly explore carrier transport. QCL thresholds can be identified by searching for the slope peak of the first derivative of the I-V curves and can be further confirmed with its alignment to the peak of the second derivative of the I-V curves. Leakage current in QCLs with oxide-blocked ridge waveguides and buried heterostructure (BH) waveguides are studied and compared. The oxide-blocking structures provide the lowest leakage current although the capped-mesa-BH (CMBH) QCLs provide the toughest durability under highly stressful operations. The leakage current of CMBH QCLs are also compared at different temperatures.

  8. Free energy cascade in gyrokinetic turbulence

    CERN Document Server

    Navarro, A Bañón; Albrecht-Marc, M; Merz, F; Görler, T; Jenko, F; Carati, D

    2010-01-01

    In gyrokinetic theory, the quadratic nonlinearity is known to play an important role in the dynamics by redistributing (in a conservative fashion) the free energy between the various active scales. In the present study, the free energy transfer is analyzed for the case of ion temperature gradient driven turbulence. It is shown that it shares many properties with the energy transfer in fluid turbulence. In particular, one finds a forward (from large to small scales), extremely local, and self-similar cascade of free energy in the plane perpendicular to the background magnetic field. These findings shed light on some fundamental properties of plasma turbulence, and encourage the development of large eddy simulation techniques for gyrokinetics.

  9. Research on Cascaded H-bridge SVG

    Directory of Open Access Journals (Sweden)

    Yannan Yu

    2014-07-01

    Full Text Available Due to the sharp increase of the non-linear loads, the power quality lagged behind the need for an adequate power system. With a fast response, low loss, low output harmonic current, SVG has become the mainstream of dynamic reactive power compensation devices. The paper introduces a multilevel cascaded H-bridge SVG, featured with DSP+FPGA dual-core control unit and fault-tolerant redundant system, which will enhance the reliability and dynamic response, reduce the switching loss and equipment cost, and increase the efficiency of the reactive power compensation. Through instructing the MATLAB simulation model of SVG and testing model machine, the design correction of medium voltage SVG power circuits and parameters is verified. The model machine is working well.

  10. Congestion and cascades in payment systems

    Science.gov (United States)

    Beyeler, Walter E.; Glass, Robert J.; Bech, Morten L.; Soramäki, Kimmo

    2007-10-01

    We develop a parsimonious model of the interbank payment system. The model incorporates an endogenous instruction arrival process, a scale-free topology of payments between banks, a fixed total liquidity which limits banks’ capacity to process arriving instructions, and a global market that distributes liquidity. We find that at low liquidity the system becomes congested and payment settlement loses correlation with payment instruction arrival, becoming coupled across the network. The onset of congestion is evidently related to the relative values of three characteristic times: the time for banks’ net position to return to 0, the time for a bank to exhaust its liquidity endowment, and the liquidity market relaxation time. In the congested regime settlement takes place in cascades having a characteristic length scale. A global liquidity market substantially attenuates congestion, requiring only a small fraction of the payment-induced liquidity flow to achieve strong beneficial effects.

  11. Cascading Node Failure with Continuous States in Random Geometric Networks

    CERN Document Server

    Kamran, Khashayar

    2016-01-01

    The increasing complexity and interdependency of today's networks highlight the importance of studying network robustness to failure and attacks. Many large-scale networks are prone to cascading effects where a limited number of initial failures (due to attacks, natural hazards or resource depletion) propagate through a dependent mechanism, ultimately leading to a global failure scenario where a substantial fraction of the network loses its functionality. These cascading failure scenarios often take place in networks which are embedded in space and constrained by geometry. Building on previous results on cascading failure in random geometric networks, we introduce and analyze a continuous cascading failure model where a node has an initial continuously-valued state, and fails if the aggregate state of its neighbors fall below a threshold. Within this model, we derive analytical conditions for the occurrence and non-occurrence of cascading node failure, respectively.

  12. Tolerance of edge cascades with coupled map lattices methods

    Institute of Scientific and Technical Information of China (English)

    Cui Di; Gao Zi-You; Zheng Jian-Feng

    2009-01-01

    This paper studies the cascading failure on random networks and scale-free networks by introducing the tolerance parameter of edge based on the coupled map lattices methods. The whole work focuses on investigating some indices including the number of failed edges, dynamic edge tolerance capacity and the perturbation of edge. In general, it assumes that the perturbation is attributed to the normal distribution in adopted simulations. By investigating the effectiveness of edge tolerance in scale-free and random networks, it finds that the larger tolerance parameter 位 can more efficiently delay the cascading failure process for scale-free networks than random networks. These results indicate that the cascading failure process can be effectively controlled by increasing the tolerance parameter A. Moreover, the simulations also show that, larger variance of perturbation can easily trigger the cascading failures than the smaller one. This study may be useful for evaluating efficiency of whole traffic systems, and for alleviating cascading failure in such systems.

  13. A modeling framework for system restoration from cascading failures.

    Science.gov (United States)

    Liu, Chaoran; Li, Daqing; Zio, Enrico; Kang, Rui

    2014-01-01

    System restoration from cascading failures is an integral part of the overall defense against catastrophic breakdown in networked critical infrastructures. From the outbreak of cascading failures to the system complete breakdown, actions can be taken to prevent failure propagation through the entire network. While most analysis efforts have been carried out before or after cascading failures, restoration during cascading failures has been rarely studied. In this paper, we present a modeling framework to investigate the effects of in-process restoration, which depends strongly on the timing and strength of the restoration actions. Furthermore, in the model we also consider additional disturbances to the system due to restoration actions themselves. We demonstrate that the effect of restoration is also influenced by the combination of system loading level and restoration disturbance. Our modeling framework will help to provide insights on practical restoration from cascading failures and guide improvements of reliability and resilience of actual network systems.

  14. Fluctuation sensitivity of a transcriptional signaling cascade

    Science.gov (United States)

    Pilkiewicz, Kevin R.; Mayo, Michael L.

    2016-09-01

    The internal biochemical state of a cell is regulated by a vast transcriptional network that kinetically correlates the concentrations of numerous proteins. Fluctuations in protein concentration that encode crucial information about this changing state must compete with fluctuations caused by the noisy cellular environment in order to successfully transmit information across the network. Oftentimes, one protein must regulate another through a sequence of intermediaries, and conventional wisdom, derived from the data processing inequality of information theory, leads us to expect that longer sequences should lose more information to noise. Using the metric of mutual information to characterize the fluctuation sensitivity of transcriptional signaling cascades, we find, counter to this expectation, that longer chains of regulatory interactions can instead lead to enhanced informational efficiency. We derive an analytic expression for the mutual information from a generalized chemical kinetics model that we reduce to simple, mass-action kinetics by linearizing for small fluctuations about the basal biological steady state, and we find that at long times this expression depends only on a simple ratio of protein production to destruction rates and the length of the cascade. We place bounds on the values of these parameters by requiring that the mutual information be at least one bit—otherwise, any received signal would be indistinguishable from noise—and we find not only that nature has devised a way to circumvent the data processing inequality, but that it must be circumvented to attain this one-bit threshold. We demonstrate how this result places informational and biochemical efficiency at odds with one another by correlating high transcription factor binding affinities with low informational output, and we conclude with an analysis of the validity of our assumptions and propose how they might be tested experimentally.

  15. Influence of the condensate and inverse cascade on the direct cascade in wave turbulence

    CERN Document Server

    Korotkevich, A O

    2009-01-01

    During direct numerical simulation of the isotropic turbulence of surface gravity waves in the framework of Hamiltonian equations formation of the long wave background or condensate was observed. Exponents of the direct cascade spectra at the different levels of an artificial condensate suppression show a tendency to become closer to the prediction of the wave turbulence theory at lower levels of condensate. A simple qualitative explanation of the mechanism of this phenomenon is proposed.

  16. Precise measurement of {gamma}(K{yields}e {nu}({gamma}))/{gamma}(K{yields}{mu} {nu}({gamma})) and study of K{yields}e {nu} {gamma}

    Energy Technology Data Exchange (ETDEWEB)

    Ambrosino, F.; Massarotti, P.; Meola, S.; Napolitano, M. [Dipartimento di Scienze Fisiche dell' Universita ' ' Federico II' ' , Napoli (Italy); INFN Sezione di Napoli, Napoli (Italy); Antonelli, A.; Antonelli, M.; Bencivenni, G.; Bloise, C.; Bossi, F.; Capon, G.; Capussela, T.; Ciambrone, P.; De Lucia, E.; De Simone, P.; Dreucci, M.; Felici, G.; Gatti, C.; Giovannella, S.; Jacewicz, M.; Lanfranchi, G.; Miscetti, S.; Moulson, M.; Murtas, F.; Palutan, M.; Santangelo, P.; Sciascia, B.; Sibidanov, A.; Spadaro, T.; Venanzoni, G. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Archilli, F. [Dipartimento di Fisica dell' Universita ' ' Tor Vergata' ' , Rome (Italy); INFN Sezione di Roma Tor Vergata, Rome (Italy); Beltrame, P.; Denig, A.; Mueller, S. [Johannes Gutenberg-Universitaet, Institut fuer Kernphysik, Mainz (Germany); Bini, C.; De Santis, A.; De Zorzi, G.; Di Domenico, A.; Fiore, S.; Franzini, P.; Gauzzi, P. [Dipartimento di Fisica dell' Universita ' ' La Sapienza' ' , Rome (Italy); INFN Sezione di Roma, Rome (Italy); Bocchetta, S.; Ceradini, F.; Di Micco, B.; Nguyen, F. [Dipartimento di Fisica dell' Universita ' ' Roma Tre' ' , Rome (Italy); INFN Sezione di Roma Tre, Rome (Italy); Branchini, P.; Graziani, E.; Passeri, A.; Tortora, L. [INFN Sezione di Roma Tre, Rome (Italy); Capriotti, D. [Dipartimento di Fisica dell' Universita ' ' Roma Tre' ' , Rome (Italy); Di Donato, C. [INFN Sezione di Napoli, Napoli (Italy); Kulikov, V. [Institute for Theoretical and Experimental Physics, Moscow (Russian Federation); Lee-Franzini, J. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); State University of New York, Physics Department, Stony Brook (United States); Martini, M.; Patera, V.; Versaci, R. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Dipartimento di Energetica dell' Universita ' ' La Sapienza' ' , Rome (Italy); Valente, P. [INFN Sezione di Roma, Rome (Italy)

    2009-12-15

    We present a precise measurement of the ratio R{sub K}={gamma}(K{yields}e{nu}({gamma}))/{gamma}(K{yields}{mu}{nu}({gamma})) and a study of the radiative process K{yields}e{nu}{gamma}, performed with the KLOE detector. The results are based on data collected at the Frascati e{sup +}e{sup -} collider DA {phi}NE for an integrated luminosity of 2.2 fb{sup -1}. We find R{sub K}=(2.493{+-}0.025{sub stat}{+-}0.019{sub syst}) x 10{sup -5}, in agreement with the Standard Model expectation. This result is used to improve constraints on parameters of the Minimal Supersymmetric Standard Model with lepton flavor violation. We also measured the differential decay rate d {gamma}(K{yields}e{nu}{gamma})/dE{sub {gamma}} for photon energies 10gamma}}<250 MeV. Results are compared with predictions from theory. (orig.)

  17. Interferon Gamma in Leishmaniasis

    OpenAIRE

    2013-01-01

    Leishmaniasis is a complex disease that is caused by parasites of the Leishmania genus. Leishmania are further classified into several complexes, each of which can engage in distinct interactions with mammalian hosts resulting in differing disease presentations. It is therefore not unexpected that host immune responses to Leishmania are variable. The induction of interferon gamma (IFN-γ) and response to it in these infections has received considerable attention. In this review, we summarize o...

  18. NIF Gamma Reaction History

    Science.gov (United States)

    Herrmann, H. W.; Kim, Y.; Young, C. S.; Mack, J. M.; McEvoy, A. M.; Hoffman, N. M.; Wilson, D. C.; Langenbrunner, J. R.; Evans, S.; Batha, S. H.; Stoeffl, W.; Lee, A.; Horsfield, C. J.; Rubery, M.; Miller, E. K.; Malone, R. M.; Kaufman, M. I.

    2010-11-01

    The primary objective of the NIF Gamma Reaction History (GRH) diagnostics is to provide bang time and burn width information based upon measurement of fusion gamma-rays. This is accomplished with energy-thresholded Gas Cherenkov detectors that convert MeV gamma-rays into UV/visible photons for high-bandwidth optical detection. In addition, the GRH detectors can perform γ-ray spectroscopy to explore other nuclear processes from which additional significant implosion parameters may be inferred (e.g., plastic ablator areal density). Implementation is occurring in 2 phases: 1) four PMT-based channels mounted to the outside of the NIF target chamber at ˜6 m from TCC (GRH-6m) for the 3e13-3e16 DT neutron yield range expected during the early ignition-tuning campaigns; and 2) several channels located just inside the target bay shield wall at ˜15 m from TCC (GRH-15m) with optical paths leading through the wall into well-shielded streak cameras and PMTs for the 1e16-1e20 yield range expected during the DT ignition campaign. This suite of diagnostics will allow exploration of interesting γ-ray physics well beyond the ignition campaign. Recent data from OMEGA and NIF will be shown.

  19. Energy spectra and passive tracer cascades in turbulent flows

    CERN Document Server

    Jolly, Michael

    2016-01-01

    We study the influence of the energy spectrum on the extent of the cascade range of a passive tracer in turbulent flows. The interesting cases are when there are two different spectra over the potential range of the tracer cascade (in 2D when the tracer forcing is in the inverse energy cascade range, and in 3D when the Schmidt number Sc is large). The extent of the tracer cascade range is then limited by the width of the range for the shallower of the two energy spectra. Nevertheless, we show that in dimension $d=2,3$ the tracer cascade range extends (up to a logarithm) to $\\kappa_{d\\text{D}}^{p}$, where $\\kappa_{d\\text{D}}$ is the wavenumber beyond which diffusion should dominate and $p$ is arbitrarily close to 1, provided Sc is larger than a certain power (depending on $p$) of the Grashof number. We also derive estimates which suggest that in 2D, for Sc${}\\sim1$ a wide tracer cascade can coexist with a significant inverse energy cascade at Grashof numbers large enough to produce a turbulent flow.

  20. Out of control: Fluctuation of cascading dynamics in networks

    Science.gov (United States)

    Wang, Jianwei; Cai, Lin; Xu, Bo; Li, Peng; Sun, Enhui; Zhu, Zhiguo

    2016-11-01

    Applying two preferential selection mechanisms of flow destination, we develop two new methods to quantify the initial load of a node, where the flow is transported along the shortest path between two nodes. We propose a simple cascading model and study cascading dynamics induced by attacking the node with the highest load in some synthetic and actual networks. Surprisingly, we observe the abnormal fluctuation of cascading dynamics, i.e., more damage can be triggered if we spend significantly higher cost to protect a network. In particular, this phenomenon is independent of the initial flow distribution and the preferential selection mechanisms of flow destination. However, it remains unclear which specific structural patterns may affect the fluctuation of cascading dynamics. In this paper, we examine the local evolution of the cascading propagation by constructing some special networks. We show that revivals of some nodes in the double ring structure facilitate the transportation of the flow between two unconnected sub-networks, cause more damage and subsequently lead to the abnormal fluctuation of cascading dynamics. Compared with the traditional definition of the betweenness, we adopt two new proposed methods to further evaluate the resilience of several actual networks. We find that some real world networks reach the strongest resilience level against cascading failures in our preferential selection mechanisms of flow destination. Moreover, we explore how to use the minimum cost to maximize the resilience of the studied networks.

  1. Factors Associated with PMTCT Cascade Completion in Four African Countries

    Directory of Open Access Journals (Sweden)

    Jodie Dionne-Odom

    2016-01-01

    Full Text Available Background. Many countries are working to reduce or eliminate mother-to-child transmission (MTCT of HIV. Prevention efforts have been conceptualized as steps in a cascade but cascade completion rates during and after pregnancy are low. Methods. A cross-sectional survey was performed across 26 communities in Cameroon, Cote d’Ivoire, South Africa, and Zambia. Women who reported a pregnancy within two years were enrolled. Participant responses were used to construct the PMTCT cascade with all of the following steps required for completion: at least one antenatal visit, HIV testing performed, HIV testing result received, initiation of maternal prophylaxis, and initiation of infant prophylaxis. Factors associated with cascade completion were identified using multivariable logistic regression modeling. Results. Of 976 HIV-infected women, only 355 (36.4% completed the PMTCT cascade. Although most women (69.2% did not know their partner’s HIV status; awareness of partner HIV status was associated with cascade completion (aOR 1.4, 95% CI 1.01–2.0. Completion was also associated with receiving an HIV diagnosis prior to pregnancy compared with HIV diagnosis during or after pregnancy (aOR 14.1, 95% CI 5.2–38.6. Conclusions. Pregnant women with HIV infection in Africa who were aware of their partner’s HIV status and who were diagnosed with HIV before pregnancy were more likely to complete the PMTCT cascade.

  2. Gamma-Ray Localization of Terrestrial Gamma-Ray Flashes

    CERN Document Server

    Marisaldi, M; Trois, A; Giuliani, A; Tavani, M; Labanti, C; Fuschino, F; Bulgarelli, A; Longo, F; Barbiellini, G; Del Monte, E; Moretti, E; Trifoglio, M; Costa, E; Caraveo, P; Cattaneo, P W; Chen, A; D'Ammando, F; De Paris, G; Di Cocco, G; Di Persio, G; Donnarumma, I; Evangelista, Y; Feroci, M; Ferrari, A; Fiorini, M; Froysland, T; Galli, M; Gianotti, F; Lapshov, I; Lazzarotto, F; Lipari, P; Mereghetti, S; Morselli, A; Pacciani, L; Pellizzoni, A; Perotti, F; Picozza, P; Piano, G; Pilia, M; Prest, M; Pucella, G; Rapisarda, M; Rappoldi, A; Rubini, A; Sabatini, S; Soffitta, P; Striani, E; Vallazza, E; Vercellone, S; Vittorini, V; Zambra, A; Zanello, D; Antonelli, L A; Colafrancesco, S; Cutini, S; Giommi, P; Lucarelli, F; Pittori, C; Santolamazza, P; Verrecchia, F; Salotti, L; 10.1103/PhysRevLett.105.128501

    2010-01-01

    Terrestrial Gamma-Ray Flashes (TGFs) are very short bursts of high energy photons and electrons originating in Earth's atmosphere. We present here a localization study of TGFs carried out at gamma-ray energies above 20 MeV based on an innovative event selection method. We use the AGILE satellite Silicon Tracker data that for the first time have been correlated with TGFs detected by the AGILE Mini-Calorimeter. We detect 8 TGFs with gamma-ray photons of energies above 20 MeV localized by the AGILE gamma-ray imager with an accuracy of 5-10 degrees at 50 MeV. Remarkably, all TGF-associated gamma rays are compatible with a terrestrial production site closer to the sub-satellite point than 400 km. Considering that our gamma rays reach the AGILE satellite at 540 km altitude with limited scattering or attenuation, our measurements provide the first precise direct localization of TGFs from space.

  3. In-beam gamma-ray spectroscopy of 35Mg and 33Na

    CERN Document Server

    Gade, A; Brown, B A; Campbell, C M; Cook, J M; Ettenauer, S; Glasmacher, T; Kemper, K W; McDaniel, S; Obertelli, A; Otsuka, T; Ratkiewicz, A; Terry, J R; Utsuno, Y; Weisshaar, D

    2011-01-01

    Excited states in the very neutron-rich nuclei 35Mg and 33Na were populated in the fragmentation of a 38Si projectile beam on a Be target at 83 MeV/u beam energy. We report on the first observation of gamma-ray transitions in 35Mg, the odd-N neighbor of 34Mg and 36Mg, which are known to be part of the "Island of Inversion" around N = 20. The results are discussed in the framework of large- scale shell-model calculations. For the A = 3Z nucleus 33Na, a new gamma-ray transition was observed that is suggested to complete the gamma-ray cascade 7/2+ --> 5/2+ --> 3/2+ gs connecting three neutron 2p-2h intruder states that are predicted to form a close-to-ideal K = 3/2 rotational band in the strong-coupling limit.

  4. Augmentation of ENDF/B fission product gamma-ray spectra by calculated spectra

    Energy Technology Data Exchange (ETDEWEB)

    Katakura, J. (Japan Atomic Energy Research Inst., Tokai-mura, Naka-gun, Ibaraki-ken (Japan)); England, T.R. (Los Alamos National Lab., NM (United States))

    1991-11-01

    Gamma-ray spectral data of the ENDF/B-V fission product decay data file have been augmented by calculated spectra. The calculations were performed with a model using beta strength functions and cascade gamma-ray transitions. The calculated spectra were applied to individual fission product nuclides. Comparisons with several hundred measured aggregate gamma spectra after fission were performed to confirm the applicability of the calculated spectra. The augmentation was extended to a preliminary ENDF/B-VI file, and to beta spectra. Appendix C provides information on the total decay energies for individual products and some comparisons of measured and aggregate values based on the preliminary ENDF/B-VI files. 15 refs., 411 figs.

  5. Blind Deconvolution in Nonminimum Phase Systems Using Cascade Structure

    Directory of Open Access Journals (Sweden)

    Liqing Zhang

    2007-01-01

    Full Text Available We introduce a novel cascade demixing structure for multichannel blind deconvolution in nonminimum phase systems. To simplify the learning process, we decompose the demixing model into a causal finite impulse response (FIR filter and an anticausal scalar FIR filter. A permutable cascade structure is constructed by two subfilters. After discussing geometrical structure of FIR filter manifold, we develop the natural gradient algorithms for both FIR subfilters. Furthermore, we derive the stability conditions of algorithms using the permutable characteristic of the cascade structure. Finally, computer simulations are provided to show good learning performance of the proposed method.

  6. An Improved Phase Disposition SPWM Strategy for Cascaded Multilevel Inverter

    Directory of Open Access Journals (Sweden)

    Jinbang Xu

    2014-01-01

    Full Text Available The Carrier Phase Shifted (CPS strategy is conventional for cascaded multilevel inverter, because it can naturally ensure all cascaded cells to output balanced power. However, in point of spectra of the output line voltage, CPS is suboptimal to Phase Disposition (PD strategy, because the latter can not naturally ensure power balance. This paper presents an improved PD strategy, inspiration from the disposition of CPS strategy triangle carriers. Just reconstructing the triangle carriers of PD strategy, it can not only reserve the waveform quality of the line voltage to be optimal, but also naturally ensure the output power of each cascaded cells to be balanced.

  7. Probabilistic analysis of cascade failure dynamics in complex network

    Science.gov (United States)

    Zhang, Ding-Xue; Zhao, Dan; Guan, Zhi-Hong; Wu, Yonghong; Chi, Ming; Zheng, Gui-Lin

    2016-11-01

    The impact of initial load and tolerance parameter distribution on cascade failure is investigated. By using mean field theory, a probabilistic cascade failure model is established. Based on the model, the damage caused by certain attack size can be predicted, and the critical attack size is derived by the condition of cascade failure end, which ensures no collapse. The critical attack size is larger than the case of constant tolerance parameter for network of random distribution. Comparing three typical distributions, simulation results indicate that the network whose initial load and tolerance parameter both follow Weibull distribution performs better than others.

  8. Investigation of hyperfine interactions in pure silicon and NTD silicon by means of perturbed angular {gamma}-{gamma} correlation spectroscopy; Investigacao de interacoes hiperfinas em silicio puro e silicio NTD pela tecnica de correlacao angular {gamma}-{gamma} perturbada

    Energy Technology Data Exchange (ETDEWEB)

    Cordeiro, Moacir Ribeiro

    2007-07-01

    III the present work, a microscopic investigation of hyperfine interactions in single crystal silicon samples was carried out by means of Perturbed Angular {gamma} -{gamma} correlation technique (PAC), which is based in hyperfine interactions. In order to achieve these measurements, it was used {sup 111} In {yields} {sup 111}Cd radioactive probe nuclei, which decay through the well known {gamma} cascade 171-245 keV with an intermediate level of 245 keV ( I 5{sup +}/2, Q = 0.83b, T{sub 1/2} = 84.5 ns). The samples were prepared using different probe nuclei insertion methods, making possible to increase our understanding on the impact generated by each of these techniques in PAC measurements. Ion implantation, diffusion and evaporation were carefully investigated giving emphasis on its characteristics and particularities. Then, it was made a study about the concentration of intrinsic defects as function of severe annealing processes. Finally, a comparative analysis was made for all these probe nuclei insertion methods. This work also accomplished PAC measurements in single crystal silicon doped with phosphorus by means of Neutron Transmutation Doping (NTD) method, carried out in a research nuclear reactor. The extremely high doping uniformity allied to the nonexistence of previous measurements in these materials emphasize the importance of the results obtained. These results are then compared with literature results for samples doped by conventional methods presenting the respective conclusions. (author)

  9. Gene expression profiling in cells with enhanced gamma-secretase activity.

    Directory of Open Access Journals (Sweden)

    Alexandra I Magold

    Full Text Available BACKGROUND: Processing by gamma-secretase of many type-I membrane protein substrates triggers signaling cascades by releasing intracellular domains (ICDs that, following nuclear translocation, modulate the transcription of different genes regulating a diverse array of cellular and biological processes. Because the list of gamma-secretase substrates is growing quickly and this enzyme is a cancer and Alzheimer's disease therapeutic target, the mapping of gamma-secretase activity susceptible gene transcription is important for sharpening our view of specific affected genes, molecular functions and biological pathways. METHODOLOGY/PRINCIPAL FINDINGS: To identify genes and molecular functions transcriptionally affected by gamma-secretase activity, the cellular transcriptomes of Chinese hamster ovary (CHO cells with enhanced and inhibited gamma-secretase activity were analyzed and compared by cDNA microarray. The functional clustering by FatiGO of the 1,981 identified genes revealed over- and under-represented groups with multiple activities and functions. Single genes with the most pronounced transcriptional susceptibility to gamma-secretase activity were evaluated by real-time PCR. Among the 21 validated genes, the strikingly decreased transcription of PTPRG and AMN1 and increased transcription of UPP1 potentially support data on cell cycle disturbances relevant to cancer, stem cell and neurodegenerative diseases' research. The mapping of interactions of proteins encoded by the validated genes exclusively relied on evidence-based data and revealed broad effects on Wnt pathway members, including WNT3A and DVL3. Intriguingly, the transcription of TERA, a gene of unknown function, is affected by gamma-secretase activity and was significantly altered in the analyzed human Alzheimer's disease brain cortices. CONCLUSIONS/SIGNIFICANCE: Investigating the effects of gamma-secretase activity on gene transcription has revealed several affected clusters of

  10. Gamma Oscillations and Visual Binding

    Science.gov (United States)

    Robinson, Peter A.; Kim, Jong Won

    2006-03-01

    At the root of visual perception is the mechanism the brain uses to analyze features in a scene and bind related ones together. Experiments show this process is linked to oscillations of brain activity in the 30-100 Hz gamma band. Oscillations at different sites have correlation functions (CFs) that often peak at zero lag, implying simultaneous firing, even when conduction delays are large. CFs are strongest between cells stimulated by related features. Gamma oscillations are studied here by modeling mm-scale patchy interconnections in the visual cortex. Resulting predictions for gamma responses to stimuli account for numerous experimental findings, including why oscillations and zero-lag synchrony are associated, observed connections with feature preferences, the shape of the zero-lag peak, and variations of CFs with attention. Gamma waves are found to obey the Schroedinger equation, opening the possibility of cortical analogs of quantum phenomena. Gamma instabilities are tied to observations of gamma activity linked to seizures and hallucinations.

  11. The GAMMA-400 Space Mission

    CERN Document Server

    Cumani, P; Bonvicini, V; Topchiev, N P; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Bergstrom, L; Berti, E; Bigongiari, G; Bobkov, S G; Boezio, M; Bogomolov, E A; Bonechi, S; Bongi, M; Bottai, S; Castellini, G; Cattaneo, P W; Dedenko, G L; De Donato, C; Dogiel, V A; Gorbunov, M S; Gusakov, Yu V; Hnatyk, B I; Kadilin, V V; Kaplin, V A; Kaplun, A A; Kheymits, M D; Korepanov, V E; Larsson, J; Leonov, A A; Loginov, V A; Longo, F; Maestro, P; Marrocchesi, P S; Menshenin, A L; Mikhailov, V V; Mocchiutti, E; Moiseev, A A; Mori, N; Moskalenko, I V; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Popov, A V; Rappoldi, A; Ricciarini, S; Runtso, M F; Ryde, F; Serdin, O V; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Taraskin, A A; Tiberio, A; Tyurin, E M; Ulanov, M V; Vacchi, A; Vannuccini, E; Vasilyev, G I; Yurkin, Yu T; Zampa, N; Zirakashvili, V N; Zverev, V G

    2015-01-01

    GAMMA-400 is a new space mission which will be installed on board the Russian space platform Navigator. It is scheduled to be launched at the beginning of the next decade. GAMMA-400 is designed to study simultaneously gamma rays (up to 3 TeV) and cosmic rays (electrons and positrons from 1 GeV to 20 TeV, nuclei up to 10$^{15}$-10$^{16}$ eV). Being a dual-purpose mission, GAMMA-400 will be able to address some of the most impelling science topics, such as search for signatures of dark matter, cosmic-rays origin and propagation, and the nature of transients. GAMMA-400 will try to solve the unanswered questions on these topics by high-precision measurements of the Galactic and extragalactic gamma-ray sources, Galactic and extragalactic diffuse emission and the spectra of cosmic-ray electrons + positrons and nuclei, thanks to excellent energy and angular resolutions.

  12. Simulation Study on Identifiability of UHE Gamma-ray Air Showers

    Energy Technology Data Exchange (ETDEWEB)

    Wada, Y.; Inoue, N.; Miyazawa, K. [Graduate School of Science and Engineering, Saitama University, Saitama 338-8570 (Japan); Vankov, H.P. [Institute for Nuclear Research and Nuclear Energy, Bulgaria Academy, Sofia (Bulgaria)

    2008-01-15

    The chemical composition of Ultra-High-Energy (UHE) comic rays is one of unsolved mysteries, and its study will give us fruitful information on the origin and acceleration mechanism of UHE cosmic rays. Especially, a detection of UHE gamma-rays by hybrid experiments, such as AUGER and TA, will be a key to solve these questions. The characteristics of UHE gamma-ray showers have been studied by comparing the lateral and longitudinal structures of shower particles calculated with AIRES and our own simulation code, so far. There are apparent differences in a slope of lateral distribution ({eta}) and a depth of shower maximum (Xmax) between gamma-ray and proton induced showers because UHE gamma-ray showers are affected by the LPM effect and the geomagnetic cascading process in an energy region of >10{sup 19.5}eV. Different features between gamma-ray and proton showers are pointed out from the simulation study and an identifiability of gamma-ray showers from proton ones is also discussed by the method of Neural-Network-Analysis.

  13. Cascade category-aware visual search.

    Science.gov (United States)

    Zhang, Shiliang; Tian, Qi; Huang, Qingming; Gao, Wen; Rui, Yong

    2014-06-01

    Incorporating image classification into image retrieval system brings many attractive advantages. For instance, the search space can be narrowed down by rejecting images in irrelevant categories of the query. The retrieved images can be more consistent in semantics by indexing and returning images in the relevant categories together. However, due to their different goals on recognition accuracy and retrieval scalability, it is hard to efficiently incorporate most image classification works into large-scale image search. To study this problem, we propose cascade category-aware visual search, which utilizes weak category clue to achieve better retrieval accuracy, efficiency, and memory consumption. To capture the category and visual clues of an image, we first learn category-visual words, which are discriminative and repeatable local features labeled with categories. By identifying category-visual words in database images, we are able to discard noisy local features and extract image visual and category clues, which are hence recorded in a hierarchical index structure. Our retrieval system narrows down the search space by: 1) filtering the noisy local features in query; 2) rejecting irrelevant categories in database; and 3) preforming discriminative visual search in relevant categories. The proposed algorithm is tested on object search, landmark search, and large-scale similar image search on the large-scale LSVRC10 data set. Although the category clue introduced is weak, our algorithm still shows substantial advantages in retrieval accuracy, efficiency, and memory consumption than the state-of-the-art.

  14. Probing the energy cascade of convective turbulence.

    Science.gov (United States)

    Kunnen, R P J; Clercx, H J H

    2014-12-01

    The existence of a buoyancy-dominated scaling range in convective turbulence is a longstanding open question. We investigate this issue by considering the scale-by-scale energy budget in direct numerical simulations of Rayleigh-Bénard convection. We try to minimize the so-called Bolgiano length scale, the length scale at which buoyancy becomes dominant for scaling. Therefore, we deliberately choose modest Rayleigh numbers Ra=2.5×10(6) and 2.5×10(7). The budget reveals that buoyant forcing, turbulent energy transfer, and dissipation are contributing significantly over a wide range of scales. Thereby neither Kolmogorov-like (balance of turbulent transfer and dissipation) nor Bolgiano-Obukhov-like scaling (balance of turbulent transfer and buoyancy) is expected in the structure functions, which indeed reveal inconclusive scaling behavior. Furthermore, we consider the calculation of the Bolgiano length scale. To account for correlations between the dissipation rates of kinetic energy and thermal variance we propose to average the Bolgiano length scale directly. This gives an estimate, which is one order of magnitude larger than the previous estimate, and actually larger than the domain itself. Rather than studying the scaling of structure functions, we propose that the use of scale-by-scale energy budgets resolving anisotropic contributions is appropriate to consider the energy cascade mechanisms in turbulent convection.

  15. Cascading reminiscence bumps in popular music.

    Science.gov (United States)

    Krumhansl, Carol Lynne; Zupnick, Justin Adam

    2013-10-01

    Autobiographical memories are disproportionately recalled for events in late adolescence and early adulthood, a phenomenon called the reminiscence bump. Previous studies on music have found autobiographical memories and life-long preferences for music from this period. In the present study, we probed young adults' personal memories associated with top hits over 5-and-a-half decades, as well as the context of their memories and their recognition of, preference for, quality judgments of, and emotional reactions to that music. All these measures showed the typical increase for music released during the two decades of their lives. Unexpectedly, we found that the same measures peaked for the music of participants' parents' generation. This finding points to the impact of music in childhood and suggests that these results reflect the prevalence of music in the home environment. An earlier peak occurred for 1960s music, which may be explained by its quality or by its transmission through two generations. We refer to this pattern of musical cultural transmission over generations as cascading reminiscence bumps.

  16. Optimization Issues in a Harmonic Cascade FEL

    CERN Document Server

    De Ninno, G

    2005-01-01

    Presently there is significant interest by multiple groups (e.g. BNL, ELETTRA, LBNL, BESSY, MIT) to reach short output wavelengths via a harmonic cascade FEL using an external seed laser. In a multistage device, there are a number of "free" parameters such as the nominal power of the input seed, the lengths of the individual modulator and radiator undulators, the strengths (i.e. the R56's) of the dispersive sections, the choice of the actual harmonic numbers to reach a given wavelength, etc., whose optimization is a non-trivial exercise. In particular, one can choose whether to operate predominantly in the "high gain" regime such as was proposed by Yu [1] in which case each radiator undulator is many gain lengths long or, alternatively, in the "low gain" regime in which case all undulators (except possibly the last radiator) are a couple gain lengths or less long and the output from each radiator essentially corresponds to coherent spontaneous emission from a pre-bunched beam. With particular emphasis upon th...

  17. Astronomical Forcing of Salt Marsh Biogeochemical Cascades

    Science.gov (United States)

    Morris, J. T.; Sundberg, K.

    2008-12-01

    Astronomically forced changes in the hydroperiod of a salt marsh affect the rate of marsh primary production leading to a biogeochemical cascade. For example, salt marsh primary production and biogeochemical cycles in coastal salt marshes are sensitive to the 18.6-year lunar nodal cycle, which alters the tidal amplitude by about 5 cm. For marshes that are perched high in the tidal frame, a relatively small increase in tidal amplitude and flooding lowers sediment salinity and stimulates primary production. Porewater sulfide concentrations are positively correlated with tidal amplitude and vary on the same cycle as primary production. Soluble reactive phosphate and ammonium concentrations in pore water also vary on this 18.6- year cycle. Phosphate likely responds to variation in the reaction of sulfide with iron-phosphate compounds, while the production of ammonium in sediments is coupled to the activity of diazotrophs that are carbon- limited and, therefore, are regulated by primary productivity. Ammonium also would accumulate when sulfides block nitrification. These dependencies work as a positive feedback between primary production and nutrient supply and are predictive of the near-term effects of sea-level rise.

  18. Quantum cascade laser Kerr frequency comb

    CERN Document Server

    Lecaplain, Caroline; Lucas, Erwan; Jost, John D; Kippenberg, Tobias J

    2015-01-01

    The mid-infrared (mid-IR) regime (typically the wavelength regime of $\\lambda \\sim 2.5-20 \\ \\mathrm{\\mu m}$) is an important spectral range for spectroscopy as many molecules have their fundamental rotational-vibrational absorption in this band. Recently optical frequency combs based on optical microresonators ("Kerr" combs) at the onset of the mid-IR region have been generated using crystalline resonators and integrated planar silicon micro-resonators. Here we extend for the first time Kerr combs deep into the mid-IR i.e. the 'molecular fingerprint' region. This is achieved by combining an ultra high quality (Q) factor mid-IR microresonator based on crystalline $\\mathrm{MgF_{2}}$ with the quantum cascade laser (QCL) technology. Using a tapered chalgogenide (ChG) fiber and a QCL continuous wave pump laser, frequency combs at $\\lambda\\sim 4.4\\ \\mathrm{\\mu m}$ (i.e. 2270cm$^{-1}$) are generated, that span over 600nm (i.e. 300cm$^{-1}$) in bandwidth, with a mode spacing of 14.3GHz (0.5cm$^{-1}$), corresponding t...

  19. Magnetic reconnection from a multiscale instability cascade.

    Science.gov (United States)

    Moser, Auna L; Bellan, Paul M

    2012-02-15

    Magnetic reconnection, the process whereby magnetic field lines break and then reconnect to form a different topology, underlies critical dynamics of magnetically confined plasmas in both nature and the laboratory. Magnetic reconnection involves localized diffusion of the magnetic field across plasma, yet observed reconnection rates are typically much higher than can be accounted for using classical electrical resistivity. It is generally proposed that the field diffusion underlying fast reconnection results instead from some combination of non-magnetohydrodynamic processes that become important on the 'microscopic' scale of the ion Larmor radius or the ion skin depth. A recent laboratory experiment demonstrated a transition from slow to fast magnetic reconnection when a current channel narrowed to a microscopic scale, but did not address how a macroscopic magnetohydrodynamic system accesses the microscale. Recent theoretical models and numerical simulations suggest that a macroscopic, two-dimensional magnetohydrodynamic current sheet might do this through a sequence of repetitive tearing and thinning into two-dimensional magnetized plasma structures having successively finer scales. Here we report observations demonstrating a cascade of instabilities from a distinct, macroscopic-scale magnetohydrodynamic instability to a distinct, microscopic-scale (ion skin depth) instability associated with fast magnetic reconnection. These observations resolve the full three-dimensional dynamics and give insight into the frequently impulsive nature of reconnection in space and laboratory plasmas.

  20. Compression-absorption cascade refrigeration system

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez-Seara, Jose; Sieres, Jaime; Vazquez, Manuel [Area de Maquinas y Motores Termicos, Escuela Tecnica Superior de Ingenieros Industriales, Universidade de Vigo, Campus Lagoas-Marcosende, 9, 36200 Vigo (Spain)

    2006-04-01

    This paper describes the study carried out to analyse a refrigeration system in cascade with a compression system at the low temperature stage and an absorption system at the high temperature stage to generate cooling at low temperatures, as well as the possibility of powering it by means of a cogeneration system. CO{sub 2} and NH{sub 3} have been considered as refrigerants in the compression stage and the pair NH{sub 3}-H{sub 2}O in the absorption stage. The analysis has been realized by means of a mathematical model of the refrigeration system implemented in a computer program and taking into account the characteristic operating conditions of a cogeneration system with gas engines. The paper presents the results obtained regarding the performance of the refrigeration system and the adaptability between the power requirements of the refrigeration system and the power supplied by the cogeneration system taking into account the present Spanish Regulations about the use of cogeneration systems. [Author].

  1. Applied gamma-ray spectrometry

    CERN Document Server

    Dams, R; Crouthamel, Carl E

    1970-01-01

    Applied Gamma-Ray Spectrometry covers real life application of the gamma-ray and the devices used in their experimental studies. This book is organized into 9 chapters, and starts with discussions of the various decay processes, the possible interaction mechanisms of gamma radiation with matter, and the intrinsic and extrinsic variables, which affect the observed gamma-ray and X-ray spectra. The subsequent chapters deal with the properties and fabrication of scintillation detectors, semiconductor detectors, and proportional gas counters. These chapters present some of the most widely utilized

  2. Simultaneous beta and gamma spectroscopy

    Science.gov (United States)

    Farsoni, Abdollah T.; Hamby, David M.

    2010-03-23

    A phoswich radiation detector for simultaneous spectroscopy of beta rays and gamma rays includes three scintillators with different decay time characteristics. Two of the three scintillators are used for beta detection and the third scintillator is used for gamma detection. A pulse induced by an interaction of radiation with the detector is digitally analyzed to classify the type of event as beta, gamma, or unknown. A pulse is classified as a beta event if the pulse originated from just the first scintillator alone or from just the first and the second scintillator. A pulse from just the third scintillator is recorded as gamma event. Other pulses are rejected as unknown events.

  3. Cascading failures in local-world evolving networks

    Institute of Scientific and Technical Information of China (English)

    Zhe-jing BAO; Yi-jia CAO

    2008-01-01

    The local-world (LW) evolving network model shows a transition for the degree distribution between the exponential and power-law distributions, depending on the LW size. Cascading failures under intentional attacks in LW network models with different LW sizes were investigated using the cascading failures load model. We found that the LW size has a significant impact on the network's robustness against deliberate attacks. It is much easier to trigger cascading failures in LW evolving networks with a larger LW size. Therefore, to avoid cascading failures in real networks with local preferential attachment such as the Internet, the World Trade Web and the multi-agent system, the LW size should be as small as possible.

  4. Influence of Blade Chordwise Lean on Development of Cascade Losses

    Institute of Scientific and Technical Information of China (English)

    HanWanjin; HuangHongyan; 等

    1996-01-01

    An experimetal investigation was carried out on the effect of blade chordwise lean on the losse in highly loaded rectangular turbine cascades,Datailed measurements include 10 traverses from upstream to downstream of the cascades with five-hole spherical probes.Compared with the experimental data of the coventional Straight and pitchwise lean blades under the same conditions,it is shown that the effect of chordwise lean on the development of the cascade losses is similar to that of pitchwise lean.However,the chordwise lean produces smaller streamwise adverse pressure gradients near both endwalls and a smaller spanwise negative one starting from the actute angle side in the first part of the passages in chordwise lean cascade,thereby the saddle point separations and intensities of the passage vortices are weakened and the secondary vorte losses are cut down notably.

  5. Statistical analysis of cascading failures in power grids

    Energy Technology Data Exchange (ETDEWEB)

    Chertkov, Michael [Los Alamos National Laboratory; Pfitzner, Rene [Los Alamos National Laboratory; Turitsyn, Konstantin [Los Alamos National Laboratory

    2010-12-01

    We introduce a new microscopic model of cascading failures in transmission power grids. This model accounts for automatic response of the grid to load fluctuations that take place on the scale of minutes, when optimum power flow adjustments and load shedding controls are unavailable. We describe extreme events, caused by load fluctuations, which cause cascading failures of loads, generators and lines. Our model is quasi-static in the causal, discrete time and sequential resolution of individual failures. The model, in its simplest realization based on the Directed Current description of the power flow problem, is tested on three standard IEEE systems consisting of 30, 39 and 118 buses. Our statistical analysis suggests a straightforward classification of cascading and islanding phases in terms of the ratios between average number of removed loads, generators and links. The analysis also demonstrates sensitivity to variations in line capacities. Future research challenges in modeling and control of cascading outages over real-world power networks are discussed.

  6. Enantiomer separation in a cascaded micellar-enhanced ultrafiltration system

    NARCIS (Netherlands)

    Overdevest, P.E.M.; Hoenders, M.H.J.; Riet, van 't K.; Padt, van der A.; Keurentjes, J.T.F.

    2002-01-01

    The increasing demand for optically pure compounds (enantiomers) stimulates the development of new enantiomer separation processes on an industrial scale. The separation of enantiomers by ultrafiltration of enantioselective micelles was studied in a cascaded system. The feasibility of this separatio

  7. Terahertz Quantum Cascade Laser Based 3D Imaging Project

    Data.gov (United States)

    National Aeronautics and Space Administration — LongWave Photonics proposes a terahertz quantum-cascade laser based swept-source optical coherence tomography (THz SS-OCT) system for single-sided, 3D,...

  8. Mutually independent cascades in anisotropic soap-film turbulence

    Science.gov (United States)

    Liu, Chien-Chia; Gioia, Gustavo; Chakraborty, Pinaki

    2015-03-01

    Computational, experimental and field data amassed to date indicate that in 2D turbulence the spectrum of longitudinal velocity fluctuations, E11 (k1) , and the spectrum of transverse velocity fluctuations, E22 (k1) , correspond always to the same cascade, consistent with isotropy, so that E11 (k1) ~k-α and E22 (k1) ~k-α , where the ``spectral exponent'' α is either 5/3 (for the inverse-energy cascade) or 3 (for the enstrophy cascade). Here, we carry out experiments on turbulent 2D soap-film flows in which E11 (k1) ~k - 5 / 3 and E22 (k1) ~k-3 , as if two mutually independent cascades were concurrently active within the same flow. To our knowledge, this species of spectrum has never been observed or predicted theoretically. Our finding might open up new vistas in the understanding of turbulence.

  9. Vulnerability and Cosusceptibility Determine the Size of Network Cascades

    Science.gov (United States)

    Yang, Yang; Nishikawa, Takashi; Motter, Adilson E.

    2017-01-01

    In a network, a local disturbance can propagate and eventually cause a substantial part of the system to fail in cascade events that are easy to conceptualize but extraordinarily difficult to predict. Here, we develop a statistical framework that can predict cascade size distributions by incorporating two ingredients only: the vulnerability of individual components and the cosusceptibility of groups of components (i.e., their tendency to fail together). Using cascades in power grids as a representative example, we show that correlations between component failures define structured and often surprisingly large groups of cosusceptible components. Aside from their implications for blackout studies, these results provide insights and a new modeling framework for understanding cascades in financial systems, food webs, and complex networks in general.

  10. Cascade Structure of Digital Predistorter for Power Amplifier Linearization

    Directory of Open Access Journals (Sweden)

    E. B. Solovyeva

    2015-12-01

    Full Text Available In this paper, a cascade structure of nonlinear digital predistorter (DPD synthesized by the direct learning adaptive algorithm is represented. DPD is used for linearization of power amplifier (PA characteristic, namely for compensation of PA nonlinear distortion. Blocks of the cascade DPD are described by different models: the functional link artificial neural network (FLANN, the polynomial perceptron network (PPN and the radially pruned Volterra model (RPVM. At synthesis of the cascade DPD there is possibility to overcome the ill conditionality problem due to reducing the dimension of DPD nonlinear operator approximation. Results of compensating nonlinear distortion in Wiener–Hammerstein model of PA at the GSM–signal with four carriers are shown. The highest accuracy of PA linearization is produced by the cascade DPD containing PPN and RPVM.

  11. Noise properties and cascadability of SOA-EA regenerators

    DEFF Research Database (Denmark)

    Öhman, Filip; Bischoff, Svend; Tromborg, Bjarne;

    2002-01-01

    We suggest and analyse a new device containing concatenated pairs of semiconductor optical amplifiers (SOAs) and electroabsorption modulators (EAs). The device has regenerative properties and improves the cascadability of optical fibre links....

  12. Dynamic Modeling of Cascading Failure in Power Systems

    CERN Document Server

    Song, Jiajia; Ghanavati, Goodarz; Hines, Paul D H

    2014-01-01

    The modeling of cascading failure in power systems is difficult because of the many different mechanisms involved; no single model captures all of these mechanisms. Understanding the relative importance of these different mechanisms is an important step in choosing which mechanisms need to be modeled for particular types of cascading failure analysis. This work presents a dynamic simulation model of both power networks and protection systems, which can simulate a wider variety of cascading outage mechanisms, relative to existing quasi-steady state (QSS) models. The model allows one to test the impact of different load models and protections on cascading outage sizes. This paper describes each module of the developed dynamic model and demonstrates how different mechanisms interact. In order to test the model we simulated a batch of randomly selected $N-2$ contingencies for several different static load configurations, and found that the distribution of blackout sizes and event lengths from the proposed dynamic...

  13. On periodic orbits in discrete-time cascade systems

    Directory of Open Access Journals (Sweden)

    Huimin Li

    2006-01-01

    Full Text Available We present some results on existence, minimum period, number of periodic orbits, and stability of periodic orbits in discrete-time cascade systems. Some examples are presented to illustrate these results.

  14. The biogeography of trophic cascades on US oyster reefs.

    Science.gov (United States)

    Kimbro, David L; Byers, James E; Grabowski, Jonathan H; Hughes, A Randall; Piehler, Michael F

    2014-07-01

    Predators can indirectly benefit prey populations by suppressing mid-trophic level consumers, but often the strength and outcome of trophic cascades are uncertain. We manipulated oyster reef communities to test the generality of potential causal factors across a 1000-km region. Densities of oyster consumers were weakly influenced by predators at all sites. In contrast, consumer foraging behaviour in the presence of predators varied considerably, and these behavioural effects altered the trophic cascade across space. Variability in the behavioural cascade was linked to regional gradients in oyster recruitment to and sediment accumulation on reefs. Specifically, asynchronous gradients in these factors influenced whether the benefits of suppressed consumer foraging on oyster recruits exceeded costs of sediment accumulation resulting from decreased consumer activity. Thus, although predation on consumers remains consistent, predator influences on behaviour do not; rather, they interact with environmental gradients to cause biogeographic variability in the net strength of trophic cascades.

  15. On the polar cap cascade pair multiplicity of young pulsars

    CERN Document Server

    Timokhin, A N

    2015-01-01

    We study the efficiency of pair production in polar caps of young pulsars under a variety of conditions to estimate the maximum possible multiplicity of pair plasma in pulsar magnetospheres. We develop a semi-analytic model for calculation of cascade multiplicity which allows efficient exploration of the parameter space and corroborate it with direct numerical simulations. Pair creation processes are considered separately from particle acceleration in order to assess different factors affecting cascade efficiency, with acceleration of primary particles described by recent self-consistent non-stationary model of pair cascades. We argue that the most efficient cascades operate in the curvature radiation/synchrotron regime, the maximum multiplicity of pair plasma in pulsar magnetospheres is ~few x 10^5. The multiplicity of pair plasma in magnetospheres of young energetic pulsars weakly depends on the strength of the magnetic field and the radius of curvature of magnetic field lines and has a stronger dependence ...

  16. Lateral distribution of high energy hadrons and gamma ray in air shower cores observed with emulsion chambers

    Science.gov (United States)

    Matano, T.; Machida, M.; Kawasumi, N.; Tsushima, I.; Honda, K.; Hashimoto, K.; Navia, C. E.; Matinic, N.; Aquirre, C.

    1985-01-01

    A high energy event of a bundle of electrons, gamma rays and hadronic gamma rays in an air shower core were observed. The bundles were detected with an emulsion chamber with thickness of 15 cm lead. This air shower is estimated to be initiated with a proton with energy around 10 to the 17th power to 10 to the 18th power eV at an altitude of around 100 gmc/2. Lateral distributions of the electromagnetic component with energy above 2 TeV and also the hadronic component of energy above 6 TeV of this air shower core were determined. Particles in the bundle are produced with process of the development of the nuclear cascade, the primary energy of each interaction in the cascade which produces these particles is unknown. To know the primary energy dependence of transverse momentum, the average products of energy and distance for various average energies of secondary particles are studied.

  17. Search for C-parity violation in $J/ \\psi \\to \\gamma\\gamma$ and $ \\gamma \\phi$

    CERN Document Server

    Ablikim, M; Ai, X C; Albayrak, O; Albrecht, M; Ambrose, D J; Amoroso, A; An, F F; An, Q; Bai, J Z; Ferroli, R Baldini; Ban, Y; Bennett, D W; Bennett, J V; Bertani, M; Bettoni, D; Bian, J M; Bianchi, F; Boger, E; Bondarenko, O; Boyko, I; Braun, S; Briere, R A; Cai, H; Cai, X; Cakir, O; Calcaterra, A; Cao, G F; Cetin, S A; Chang, J F; Chelkov, G; Chen, G; Chen, H S; Chen, J C; Chen, M L; Chen, S J; Chen, X; Chen, X R; Chen, Y B; Cheng, H P; Chu, X K; Chu, Y P; Cibinetto, G; Cronin-Hennessy, D; Dai, H L; Dai, J P; Dedovich, D; Deng, Z Y; Denig, A; Denysenko, I; Destefanis, M; De Mori, F; Ding, Y; Dong, C; Dong, J; Dong, L Y; Dong, M Y; Du, S X; Fan, J Z; Fang, J; Fang, S S; Fang, Y; Fava, L; Feldbauer, F; Felici, G; Feng, C Q; Fioravanti, E; Fu, C D; Gao, Q; Gao, Y; Garzia, I; Geng, C; Goetzen, K; Gong, W X; Gradl, W; Greco, M; Gu, M H; Gu, Y T; Guan, Y H; Guo, A Q; Guo, L B; Guo, T; Guo, Y P; Haddadi, Z; Han, S; Han, Y L; Harris, F A; He, K L; He, Z Y; Held, T; Heng, Y K; Hou, Z L; Hu, C; Hu, H M; Hu, J F; Hu, T; Huang, G M; Huang, G S; Huang, H P; Huang, J S; Huang, X T; Huang, Y; Hussain, T; Ji, Q; Ji, Q P; Ji, X B; Ji, X L; Jiang, L L; Jiang, L W; Jiang, X S; Jiao, J B; Jiao, Z; Jin, D P; Jin, S; Johansson, T; Julin, A; Kalantar-Nayestanaki, N; Kang, X L; Kang, X S; Kavatsyuk, M; Ke, B C; Kloss, B; Kolcu, O B; Kopf, B; Kornicer, M; Kuehn, W; Kupsc, A; Lai, W; Lange, J S; Lara, M; Larin, P; Leyhe, M; Li, Cheng; Li, Cui; Li, D M; Li, F; Li, G; Li, H B; Li, J C; Li, Jin; Li, K; Li, Q J; Li, T; Li, W D; Li, W G; Li, X H; Li, X L; Li, X N; Li, X Q; Li, Z B; Liang, H; Liang, Y F; Liang, Y T; Lin, D X; Liu, B J; Liu, C L; Liu, C X; Liu, F H; Liu, Fang; Liu, Feng; Liu, H B; Liu, H H; Liu, H M; Liu, J; Liu, J P; Liu, K; Liu, K Y; Liu, Q; Liu, S B; Liu, X; Liu, X X; Liu, Y B; Liu, Z A; Liu, Zhiqiang; Liu, Zhiqing; Loehner, H; Lou, X C; Lu, H J; Lu, J G; Lu, R Q; Lu, Y; Lu, Y P; Luo, C L; Luo, M X; Luo, T; Luo, X L; Lv, M; Lyu, X R; Ma, F C; Ma, H L; Ma, Q M; Ma, S; Ma, T; Ma, X Y; Maas, F E; Maggiora, M; Malik, Q A; Mao, Y J; Mao, Z P; Marcello, S; Messchendorp, J G; Min, J; Min, T J; Mitchell, R E; Mo, X H; Mo, Y J; Moeini, H; Morales, C Morales; Moriya, K; Muchnoi, N Yu; Muramatsu, H; Nefedov, Y; Nerling, F; Nikolaev, I B; Ning, Z; Nisar, S; Niu, S L; Niu, X Y; Olsen, S L; Ouyang, Q; Pacetti, S; Patteri, P; Pelizaeus, M; Peng, H P; Peters, K; Ping, J L; Ping, R G; Poling, R; Pu, Y N; Qi, M; Qian, S; Qiao, C F; Qin, L Q; Qin, N; Qin, X S; Qin, Y; Qin, Z H; Qiu, J F; Rashid, K H; Redmer, C F; Ren, H L; Ripka, M; Rong, G; Ruan, X D; Santoro, V; Sarantsev, A; Savrié, M; Schoenning, K; Schumann, S; Shan, W; Shao, M; Shen, C P; Shen, X Y; Sheng, H Y; Shepherd, M R; Song, W M; Song, X Y; Sosio, S; Spataro, S; Spruck, B; Sun, G X; Sun, J F; Sun, S S; Sun, Y J; Sun, Y Z; Sun, Z J; Sun, Z T; Tang, C J; Tang, X; Tapan, I; Thorndike, E H; Tiemens, M; Toth, D; Ullrich, M; Uman, I; Varner, G S; Wang, B; Wang, B L; Wang, D; Wang, D Y; Wang, K; Wang, L L; Wang, L S; Wang, M; Wang, P; Wang, P L; Wang, Q J; Wang, S G; Wang, W; Wang, X F; Wang, Y D; Wang, Y F; Wang, Y Q; Wang, Z; Wang, Z G; Wang, Z H; Wang, Z Y; Wei, D H; Wei, J B; Weidenkaff, P; Wen, S P; Werner, M; Wiedner, U; Wolke, M; Wu, L H; Wu, Z; Xia, L G; Xia, Y; Xiao, D; Xiao, Z J; Xie, Y G; Xiu, Q L; Xu, G F; Xu, L; Xu, Q J; Xu, Q N; Xu, X P; Xue, Z; Yan, L; Yan, W B; Yan, W C; Yan, Y H; Yang, H X; Yang, L; Yang, Y; Yang, Y X; Ye, H; Ye, M; Ye, M H; Yu, B X; Yu, C X; Yu, H W; Yu, J S; Yuan, C Z; Yuan, W L; Yuan, Y; Yuncu, A; Zafar, A A; Zallo, A; Zang, S L; Zeng, Y; Zhang, B X; Zhang, B Y; Zhang, C; Zhang, C C; Zhang, D H; Zhang, H H; Zhang, H Y; Zhang, J J; Zhang, J Q; Zhang, J W; Zhang, J Y; Zhang, J Z; Zhang, L; Zhang, S H; Zhang, X J; Zhang, X Y; Zhang, Y; Zhang, Y H; Zhang, Z H; Zhang, Z P; Zhang, Z Y; Zhao, G; Zhao, J W; Zhao, J Z; Zhao, Lei; Zhao, Ling; Zhao, M G; Zhao, Q; Zhao, Q W; Zhao, S J; Zhao, T C; Zhao, Y B; Zhao, Z G; Zhemchugov, A; Zheng, B; Zheng, J P; Zheng, Y H; Zhong, B; Zhou, L; Zhou, Li; Zhou, X; Zhou, X R; Zhou, X Y; Zhu, K; Zhu, K J; Zhu, X L; Zhu, Y C; Zhu, Y S; Zhu, Z A; Zhuang, J; Zou, B S; Zou, J H

    2014-01-01

    Using $1.06\\times10^8$ $\\psi(3686)$ events recorded in $e^{+}e^{-}$ collisions at $\\sqrt{s}=$ 3.686 GeV with the BESIII at the BEPCII collider, we present searches for C-parity violation in $J/\\psi \\to \\gamma\\gamma$ and $ \\gamma \\phi$ decays via $\\psi(3686) \\to J/\\psi \\pi^+\\pi^-$. No significant signals are observed in either channel. Upper limits on the branching fractions are set to be $\\mathcal{B}(J/\\psi \\to \\gamma\\gamma) < 2.7 \\times 10^{-7}$ and $\\mathcal{B}(J/\\psi \\to \\gamma\\phi) < 1.4 \\times 10^{-6}$ at the 90\\% confidence level. The former is one order of magnitude more stringent than the previous upper limit, and the latter represents the first limit on this decay channel.

  18. Determination of the $e^+ e^- \\to \\gamma \\gamma (\\gamma)$ cross-section at LEP 2

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alderweireld, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, Ugo; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Ballestrero, A; Bambade, P; Barbier, R; Bardin, Dimitri Yuri; Barker, G J; Baroncelli, A; Battaglia, Marco; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N C; Benvenuti, Alberto C; Bérat, C; Berggren, M; Berntzon, L; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Bugge, L; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F R; Chapkin, M M; Charpentier, P; Checchia, P; Chierici, R; Shlyapnikov, P; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Dalmau, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L S; Di Ciaccio, L; Di Simone, A; Doroba, K; Drees, J; Dris, M; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J A; Gandelman, M; García, C; Gavillet, P; Gazis, E N; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Herr, H; Hoffman, J; Holmgren, S O; Holt, P J; Houlden, M A; Hultqvist, K; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Johansson, P D; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Katsoufis, E C; Kernel, G; Kersevan, B P; Kerzel, U; Kiiskinen, A P; King, B T; Kjaer, N J; Kluit, P; Kokkinias, P; Kourkoumelis, C; Kuznetsov, O; Krumshtein, Z; Kucharczyk, M; Lamsa, J; Leder, G; Ledroit, F; Leinonen, L; Leitner, R; Lemonne, J; Lepeltier, V; Lesiak, T; Liebig, W; Liko, D; Lipniacka, A; Lopes, J H; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Mazzucato, F; Mazzucato, M; McNulty, R; Meroni, C; Migliore, E; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Mönig, K; Monge, R; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Mulders, M; Mundim, L; Murray, W; Muryn, B; Myatt, G; Myklebust, T; Nassiakou, M; Navarria, Francesco Luigi; Nawrocki, K; Nicolaidou, R; Nikolenko, M; Oblakowska-Mucha, A; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, R; Österberg, K; Ouraou, A; Oyanguren, A; Paganoni, M; Paiano, S; Palacios, J P; Palka, H; Papadopoulou, T D; Pape, L; Parkes, C; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V F; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Pozdnyakov, V; Pukhaeva, N; Pullia, Antonio; Rames, J; Read, A; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Roudeau, P; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Salmi, L; Salt, J; Sander, C; Savoy-Navarro, A; Schwickerath, U; Segar, A; Sekulin, R L; Siebel, M; Sissakian, A N; Smadja, G; Smirnova, O G; Sokolov, A; Sopczak, A; Sosnowski, R; Spassoff, Tz; Stanitzki, M; Stocchi, A; Strauss, J; Stugu, B; Szczekowski, M; Szeptycka, M; Szumlak, T; Tabarelli de Fatis, T; Taffard, A C; Tegenfeldt, F; Timmermans, J; Tkatchev, L G; Tobin, M; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G; van Dam, P; Van Eldik, J; Van Lysebetten, A; Van Remortel, N; Van Vulpen, I; Vegni, G; Veloso, F; Venus, W A; Verdier, P; Verzi, V; Vilanova, D; Vitale, L; Vrba, V; Wahlen, H; Washbrook, A J; Weiser, C; Wicke, D; Wickens, J H; Wilkinson, G; Winter, M; Witek, M; Yushchenko, O P; Zalewska-Bak, A; Zalewski, P; Zavrtanik, D; Zhuravlov, V; Zimin, N I; Zintchenko, A; Zupan, M

    2004-01-01

    A test of the benchmark QED process e+e- -> gamma gamma (gamma) is reported, using the data collected with the DELPHI detector at LEP 2. The data analysed were recorded at centre-of-mass energies ranging from 161 GeV to 208 GeV and correspond to a total integrated luminosity of 656.4 pb^{-1}. The Born cross-section for the process e+e- -> gamma gamma (gamma) was determined, confirming the validity of QED at the highest energies ever attained in electron-positron collisions. Lower limits on the parameters of a number of possible deviations from QED, predicted within theoretical frameworks expressing physics beyond the Standard Model, were derived.

  19. Aeroelasticity in Turbomachines. Comparison of Theoretical and Experimental Cascade Results.

    Science.gov (United States)

    1986-01-01

    time: T = t/T o To period of a cycle s t time s v velocity m/s Vre f reference velocity for reduced frequency m/s Vref Y for compresor cascade Vref...or quasi- three-dimensional cascades. Such interesting phenomena as rotor-stator interactions, stalled flutter and fully three-dimensional effects... stall , choke, shockwaves, coupling effects between the steady and unsteady flow fields...). The distribution of the blade surface pressure difference

  20. Synthesis of Pyridoacridines through Anionic Cascade Ring Closure

    DEFF Research Database (Denmark)

    Petersen, I.N.; Kristensen, Jesper Langgaard

    2014-01-01

    A new synthesis of 13-deazaascididemin (AK-37) based on a recently developed anionic cascade ring closure is presented. Although the isolated yields are modest, the approach provides ready access to new substituted derivatives of 13-deazaascididemin. © Georg Thieme Verlag.......A new synthesis of 13-deazaascididemin (AK-37) based on a recently developed anionic cascade ring closure is presented. Although the isolated yields are modest, the approach provides ready access to new substituted derivatives of 13-deazaascididemin. © Georg Thieme Verlag....

  1. Cascaded Soliton Compression of Energetic Femtosecond Pulses at 1030 nm

    DEFF Research Database (Denmark)

    Bache, Morten; Zhou, Binbin

    2012-01-01

    We discuss soliton compression with cascaded second-harmonic generation of energetic femtosecond pulses at 1030 nm. We discuss problems encountered with soliton compression of long pulses and show that sub-10 fs compressed pulses can be achieved.......We discuss soliton compression with cascaded second-harmonic generation of energetic femtosecond pulses at 1030 nm. We discuss problems encountered with soliton compression of long pulses and show that sub-10 fs compressed pulses can be achieved....

  2. Hydrothermal monitoring data from the Cascade Range, northwestern United States

    Science.gov (United States)

    Ingebritsen, Steven E.; Gelwick, Katrina D.; Randolph-Flagg, Noah G.; Crankshaw, Ilana M.; Lundstrom, Elizabeth A.; McCulloch, Callum L.; Murveit, Anna M.; Newman, Alice C.; Mariner, Robert H.; Bergfeld, D.; Tucker, Dave S.; Schmidt, Mariek E.; Spicer, Kurt R.; Mosbrucker, Adam; Evans, William C.

    2013-01-01

    This database serves as a repository for hydrothermal-monitoring data collected at 25 sites in the U.S. portion of the Cascade Range volcanic arc. These data are intended to quantify baseline hydrothermal variability at most (10 of 12) of the highest-risk volcanoes in the Cascades, as defined by the U.S. Geological Survey’s (USGS’) National Volcanic Early Warning System (NVEWS) report (Ewert and others, 2005).

  3. Linewidth and tuning characteristics of terahertz quantum cascade lasers.

    Science.gov (United States)

    Barkan, A; Tittel, F K; Mittleman, D M; Dengler, R; Siegel, P H; Scalari, G; Ajili, L; Faist, J; Beere, H E; Linfield, E H; Davies, A G; Ritchie, D A

    2004-03-15

    We have measured the spectral linewidths of three continuous-wave quantum cascade lasers operating at terahertz frequencies by heterodyning the free-running quantum cascade laser with two far-infrared gas lasers. Beat notes are detected with a GaAs diode mixer and a microwave spectrum analyzer, permitting very precise frequency measurements and giving instantaneous linewidths of less than -30 kHz. Characteristics are also reported for frequency tuning as the injection current is varied.

  4. The cascade of HIV care in Russia, 2011–2013

    OpenAIRE

    Anastasia Pokrovskaya; Anna Popova; Natalia Ladnaya; Oleg Yurin

    2014-01-01

    Introduction: The cascade of HIV care is one of the main tools to assess the individual and public health benefits of antiretroviral therapy (ART) and identify barriers of treatment as prevention (TasP) concept realization. We aimed to characterize the changes in engagement of HIV-positive persons in care in Russia during three years (2011–2013). Methods: We defined seven steps in the cascade of care framework: HIV infected (estimation data), HIV diagnosed, linked to HIV care, retained in HIV...

  5. Digital gamma-gamma coincidence HPGe system for environmental analysis

    DEFF Research Database (Denmark)

    Markovic, Nikola; Roos, Per; Nielsen, Sven Poul

    2017-01-01

    The performance of a new gamma-gamma coincidence spectrometer system for environmental samples analysis at the Center for Nuclear Technologies of the Technical University of Denmark (DTU) is reported. Nutech Coincidence Low Energy Germanium Sandwich (NUCLeGeS) system consists of two HPGe detector...

  6. Advantages of exclusive \\gamma\\gamma production to probe high mass systems

    CERN Document Server

    Martin, A D

    2016-01-01

    We recall that the exclusive production of high mass objects via \\gamma\\gamma fusion at the LHC is not strongly suppressed in comparison with inclusive \\gamma\\gamma fusion. Therefore it may be promising to study new objects produced by the \\gamma\\gamma subprocess in experiments with exclusive kinematics. We list the main advantages of exclusive experiments.

  7. The GAMMA-400 Space Experiment: Gammas, Electrons and Nuclei Measurements

    Science.gov (United States)

    Mocchiutti, E.; Galper, A. M.; Adriani, O.; Aptekar, R. L.; Arkhangelskaja, I. V.; Arkhangelskiy, A. I.; Boezio, M.; Bonvicini, V.; Boyarchuk, K. A.; Carbone, R.; Cumani, P.; Fradkin, M. I.; Gusakov, Yu. V.; Kaplin, V. A.; Kachanov, V. A.; Kheymits, M. D.; Leonov, A. A.; Longo, F.; Mazets, E. P.; Maestro, P.; Marrocchesi, P.; Mereminskiy, I. A.; Mikhailov, V. V.; Moiseev, A. A.; Mori, N.; Moskalenko, I. V.; Naumov, P. Yu.; Papini, P.; Picozza, P.; Rodin, V. G.; Runtso, M. F.; Sarkar, R.; Sparvoli, R.; Spillantini, P.; Suchkov, S. I.; Tavani, M.; Topchiev, N. P.; Vacchi, A.; Vannuccini, E.; Yurkin, Yu. T.; Zampa, N.; Zverev, V. G.; Zirakashvili, V. N.

    2013-06-01

    The present design of the new space gamma-ray telescope GAMMA-400 for the energy range 50 MeV-3 TeV is presented. The proposed instrument has an angular resolution of 1-2 degrees at E(γ)˜100 MeV and ˜0.01 degrees at E(γ)>100 GeV and an energy resolution ˜1% at E(γ)>100 GeV. By means of a deep segmented calorimeter high energy electron flux can be studied, with a proton rejection factor of about 106. The GAMMA-400 experiment is optimized to address a broad range of science topics, such as search for signatures of dark matter, studies of galactic and extragalactic gamma-ray sources, galactic and extragalactic diffuse emission, gamma-ray bursts, as well as high-precision measurements of spectra of high energy electrons, protons and nuclei up to the knee.

  8. Gamma-Gamma Absorption in the Broad Line Region Radiation Fields of Gamma-Ray Blazars

    CERN Document Server

    Boettcher, Markus

    2016-01-01

    The expected level of gamma-gamma absorption in the Broad Line Region (BLR) radiation field of gamma-ray loud Flat Spectrum Radio Quasars (FSRQs)is evaluated as a function of the location of the gamma-ray emission region. This is done self-consistently with parameters inferred from the shape of the spectral energy distribution (SED) in a single-zone leptonic EC-BLR model scenario. We take into account all geometrical effects both in the calculation of the gamma-gamma opacity and the normalization of the BLR radiation energy density. As specific examples, we study the FSRQs 3C279 and PKS 1510-089, keeping the BLR radiation energy density at the location of the emission region fixed at the values inferred from the SED. We confirm previous findings that the optical depth due to $\\gamma\\gamma$ absorption in the BLR radiation field exceeds unity for both 3C279 and PKS 1510-089 for locations of the gamma-ray emission region inside the inner boundary of the BLR. It decreases monotonically, with distance from the cen...

  9. Longitudinal gradients along a reservoir cascade

    Science.gov (United States)

    Miranda, L.E.; Habrat, M.D.; Miyazono, S.

    2008-01-01

    Reservoirs have traditionally been regarded as spatially independent entities rather than as longitudinal segments of a river system that are connected upstream and downstream to the river and other reservoirs. This view has frustrated advancement in reservoir science by impeding adequate organization of available information and by hindering interchanges with allied disciplines that often consider impounded rivers at the basin scale. We analyzed reservoir morphology, water quality, and fish assemblage data collected in 24 reservoirs of the Tennessee River; we wanted to describe longitudinal changes occurring at the scale of the entire reservoir series (i.e., cascade) and to test the hypothesis that fish communities and environmental factors display predictable gradients like those recognized for unimpounded rivers. We used a data set collected over a 7-year period; over 3 million fish representing 94 species were included in the data set. Characteristics such as reservoir mean depth, relative size of the limnetic zone, water retention time, oxygen stratification, thermal stratification, substrate size, and water level fluctuations increased in upstream reservoirs. Conversely, reservoir area, extent of riverine and littoral zones, access to floodplains and associated wetlands, habitat diversity, and nutrient and sediment inputs increased in downstream reservoirs. Upstream reservoirs included few, largely lacustrine, ubiquitous fish taxa that were characteristic of the lentic upper reaches of the basin. Fish species richness increased in a downstream direction from 12 to 67 species/ reservoir as riverine species became more common. Considering impoundments at a basin scale by viewing them as sections in a river or links in a chain may generate insight that is not always available when the impoundments are viewed as isolated entities. Basin-scale variables are rarely controllable but constrain the expression of processes at smaller scales and can facilitate the

  10. Cascadable excitability in optically injected microdisks

    Science.gov (United States)

    Van Vaerenbergh, Thomas; Alexander, Koen; Fiers, Martin; Mechet, Pauline; Dambre, Joni; Bienstman, Peter

    2014-05-01

    All-optical spiking neural networks would allow high speed parallelized processing of time-encoded information, using the same energy efficient computational principles as our brain. As the neurons in these networks need to be able to process pulse trains, they should be excitable. Using simulations, we demonstrate Class 1 excitability in optically injected microdisk lasers, and propose a cascadable optical spiking neuron design. The neuron has a clear threshold and an integrating behavior. In addition, we show that the optical phase of the input pulses can be used to create inhibitory, as well as excitatory perturbations. Furthermore, we incorporate our optical neuron design in a topology that allows a disk to react on excitations from other disks. Phase tuning of the intermediate connections allows to control the disk response. Additionally, we investigate the sensitivity of the disk circuit to deviations in driving current and locking signal wavelength detuning. Using state-of-the-art fabrication techniques for microdisk laser, the standard deviation of the lasing wavelength is still about one order of magnitude too large. Finally, as the dynamical behavior of the microdisks is identical to the behavior in Semiconductor Ring Lasers (SRL), we compare the excitability mechanism due to optically injection with the previously proposed excitability due to asymmetry in the intermodal coupling in SRLs, as the latter mechanism can also be induced in disks due to, e.g., asymmetry in the external reaction. In both cases, the symmetry between the two counter-propagating modes of the cavity needs to be broken to prevent switching to the other mode, and allow the system to relax to its initial state after a perturbation. However, the asymmetry due to optical injection results in an integrating spiking neuron, whereas the asymmetry in the intermodal coupling is known to result in a resonating spiking neuron.

  11. Low power-consumption quantum cascade lasers

    Science.gov (United States)

    Katsuyama, Tsukuru; Hashimoto, Jun-ichi; Yoshinaga, Hiroyuki; Mori, Hiroki; Tsuji, Yukihiro; Murata, Makoto; Ekawa, Mitsuru; Tanahashi, Toshiyuki

    2015-01-01

    Quantum cascade lasers (QCLs) are promising light sources for real time high-sensitivity gas sensing in the mid-infrared region. For the practical use of QCLs as a compact and portable gas sensor, their power-consumption needs to be reduced. We report a successful operation of a low power-consumption distributed feedback (DFB) QCL. For the reduction of power consumption, we introduced a vertical-transition structure in a core region to improve carrier transition efficiency and reduced the core volume. DFB-QCL epitaxial structure was grown by low-pressure OMVPE. The core region consists of AlInAs/GaInAs superlattices lattice-matched to InP. A first-order Bragg-grating was formed near the core region to obtain a large coupling coefficiency. A mesa-strip was formed by reactive ion etching and a buried-heterostructure was fabricated by the regrowth of semi-insulating InP. High-reflective facet coatings were also performed to decrease the mirror loss for the reduction of the threshold current. A device (5x500μm) operated with a single mode in the wavelength region from 7.23μm to 7.27μm. The threshold current and threshold voltage under CW operation at 20 °C were 52mA and 8.4V respectively. A very low threshold power-consumption as low as 0.44 W was achieved, which is among the lowest values at room temperature to our knowledge.

  12. Colliding. gamma. e and. gamma gamma. beams from single-pass e/sup +/e/sup -/ accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Ginzburg, I.F.; Kotkin, G.L.; Serbo, V.G.; Tel' nov, V.I.

    1983-08-01

    A detailed discussion is given of the main characteristics of ..gamma..e and ..gamma gamma.. collisions in the scheme previously proposed by the authors for obtaining colliding ..gamma..e and ..gamma gamma.. beams on the basis of the planned linear accelerators with e/sup +/e/sup -/ colliding beams VLEPP and SLC. It is proposed to obtain intense ..gamma.. beams with energy ..omega..approx.E/sub e/> or =50 GeV by scattering of laser light focused onto the electron beams of these accelerators. In the case when the maximum luminosity is achieved, L/sub gammae/approx.L/sub e/e or L/sub gammagamma/approx.L/sub e/e, the distribution of the luminosity in the invariant mass of the ..gamma..e or ..gamma gamma.. system is broad. Monochromatization of the collisions to a level 5--10% is possible. It involves a decrease of luminosity and is most efficient for use of electrons and laser photons with helicities of opposite sign. Examples of interesting physics problems for the proposed ..gamma..e and ..gamma gamma.. beams are given.

  13. Airborne gamma-ray spectrometry

    DEFF Research Database (Denmark)

    Hovgaard, Jens

    A new method - Noise Adjusted Singular Value Decomposition, NASVD - for processing gamma-ray spectra has been developed as part of a Ph.D. project. By using this technique one is able to decompose a large set of data - for example from airborne gamma-ray surveys - into a few spectral components. ...

  14. FERMI Observations of Gamma -Ray Emission From the Moon

    Science.gov (United States)

    Abdo, A. A.; Ackermann, M.; Ajello, M.; Atwoo, W. B.; Baldini, I.; Ballet, J.; Barbiellini, G.; Bastieri, D.; Bechtol, K.; Bellazzini, R.; Berenji, B.; Blandford, R. D.; Bonamente, E.; Borgland, A. W.; Bottacini, E.; Bouvier, A.; Bregeon, J.; Brigida, M.; Bruel, P.; Buehler, R.; Gehrels, N.; Hays, E.; Thompson, D. J.; McEnery, J. E.; Troja, E.

    2012-01-01

    We report on the detection of high-energy ? -ray emission from the Moon during the first 24 months of observations by the Fermi Large Area Telescope (LAT). This emission comes from particle cascades produced by cosmicray (CR) nuclei and electrons interacting with the lunar surface. The differential spectrum of the Moon is soft and can be described as a log-parabolic function with an effective cutoff at 2-3 GeV, while the average integral flux measured with the LAT from the beginning of observations in 2008 August to the end of 2010 August is F(greater than100 MeV) = (1.04 plus or minus 0.01 [statistical error] plus or minus 0.1 [systematic error]) × 10(sup -6) cm(sup -2) s(sup -1). This flux is about a factor 2-3 higher than that observed between 1991 and 1994 by the EGRET experiment on board the Compton Gamma Ray Observatory, F(greater than100 MeV)˜5×10(sup -7) cm(sup -2) s(sup -1), when solar activity was relatively high. The higher gamma -ray flux measured by Fermi is consistent with the deep solar minimum conditions during the first 24 months of the mission, which reduced effects of heliospheric modulation, and thus increased the heliospheric flux of Galactic CRs. A detailed comparison of the light curve with McMurdo Neutron Monitor rates suggests a correlation of the trends. The Moon and the Sun are so far the only known bright emitters of gamma-rays with fast celestial motion. Their paths across the sky are projected onto the Galactic center and high Galactic latitudes as well as onto other areas crowded with high-energy gamma-ray sources. Analysis of the lunar and solar emission may thus be important for studies of weak and transient sources near the ecliptic.

  15. AGATA - Advanced Gamma Tracking Array

    CERN Document Server

    Akkoyun, S; Alikhani, B; Ameil, F; de Angelis, G; Arnold, L; Astier, A; Ataç, A; Aubert, Y; Aufranc, C; Austin, A; Aydin, S; Azaiez, F; Badoer, S; Balabanski, D L; Barrientos, D; Baulieu, G; Baumann, R; Bazzacco, D; Beck, F A; Beck, T; Bednarczyk, P; Bellato, M; Bentley, M A; Benzoni, G; Berthier, R; Berti, L; Beunard, R; Bianco, G Lo; Birkenbach, B; Bizzeti, P G; Bizzeti-Sona, A M; Blanc, F Le; Blasco, J M; Blasi, N; Bloor, D; Boiano, C; Borsato, M; Bortolato, D; Boston, A J; Boston, H C; Bourgault, P; Boutachkov, P; Bouty, A; Bracco, A; Brambilla, S; Brawn, I P; Brondi, A; Broussard, S; Bruyneel, B; Bucurescu, D; Burrows, I; Bürger, A; Cabaret, S; Cahan, B; Calore, E; Camera, F; Capsoni, A; Carrió, F; Casati, G; Castoldi, M; Cederwall, B; Cercus, J -L; Chambert, V; Chambit, M El; Chapman, R; Charles, L; Chavas, J; Clément, E; Cocconi, P; Coelli, S; Coleman-Smith, P J; Colombo, A; Colosimo, S; Commeaux, C; Conventi, D; Cooper, R J; Corsi, A; Cortesi, A; Costa, L; Crespi, F C L; Cresswell, J R; Cullen, D M; Curien, D; Czermak, A; Delbourg, D; Depalo, R; Descombes, T; Désesquelles, P; Detistov, P; Diarra, C; Didierjean, F; Dimmock, M R; Doan, Q T; Domingo-Pardo, C; Doncel, M; Dorangeville, F; Dosme, N; Drouen, Y; Duchêne, G; Dulny, B; Eberth, J; Edelbruck, P; Egea, J; Engert, T; Erduran, M N; Ertürk, S; Fanin, C; Fantinel, S; Farnea, E; Faul, T; Filliger, M; Filmer, F; Finck, Ch; de France, G; Gadea, A; Gast, W; Geraci, A; Gerl, J; Gernhäuser, R; Giannatiempo, A; Giaz, A; Gibelin, L; Givechev, A; Goel, N; González, V; Gottardo, A; Grave, X; Grȩbosz, J; Griffiths, R; Grint, A N; Gros, P; Guevara, L; Gulmini, M; Görgen, A; Ha, H T M; Habermann, T; Harkness, L J; Harroch, H; Hauschild, K; He, C; Hernández-Prieto, A; Hervieu, B; Hess, H; Hüyük, T; Ince, E; Isocrate, R; Jaworski, G; Johnson, A; Jolie, J; Jones, P; Jonson, B; Joshi, P; Judson, D S; Jungclaus, A; Kaci, M; Karkour, N; Karolak, M; Kaşkaş, A; Kebbiri, M; Kempley, R S; Khaplanov, A; Klupp, S; Kogimtzis, M; Kojouharov, I; Korichi, A; Korten, W; Kröll, Th; Krücken, R; Kurz, N; Ky, B Y; Labiche, M; Lafay, X; Lavergne, L; Lazarus, I H; Leboutelier, S; Lefebvre, F; Legay, E; Legeard, L; Lelli, F; Lenzi, S M; Leoni, S; Lermitage, A; Lersch, D; Leske, J; Letts, S C; Lhenoret, S; Lieder, R M; Linget, D; Ljungvall, J; Lopez-Martens, A; Lotodé, A; Lunardi, S; Maj, A; van der Marel, J; Mariette, Y; Marginean, N; Marginean, R; Maron, G; Mather, A R; Mȩczyński, W; Mendéz, V; Medina, P; Melon, B; Menegazzo, R; Mengoni, D; Merchan, E; Mihailescu, L; Michelagnoli, C; Mierzejewski, J; Milechina, L; Million, B; Mitev, K; Molini, P; Montanari, D; Moon, S; Morbiducci, F; Moro, R; Morrall, P S; Möller, O; Nannini, A; Napoli, D R; Nelson, L; Nespolo, M; Ngo, V L; Nicoletto, M; Nicolini, R; Noa, Y Le; Nolan, P J; Norman, M; Nyberg, J; Obertelli, A; Olariu, A; Orlandi, R; Oxley, D C; Özben, C; Ozille, M; Oziol, C; Pachoud, E; Palacz, M; Palin, J; Pancin, J; Parisel, C; Pariset, P; Pascovici, G; Peghin, R; Pellegri, L; Perego, A; Perrier, S; Petcu, M; Petkov, P; Petrache, C; Pierre, E; Pietralla, N; Pietri, S; Pignanelli, M; Piqueras, I; Podolyak, Z; Pouhalec, P Le; Pouthas, J; Pugnére, D; Pucknell, V F E; Pullia, A; Quintana, B; Raine, R; Rainovski, G; Ramina, L; Rampazzo, G; La Rana, G; Rebeschini, M; Recchia, F; Redon, N; Reese, M; Reiter, P; Regan, P H; Riboldi, S; Richer, M; Rigato, M; Rigby, S; Ripamonti, G; Robinson, A P; Robin, J; Roccaz, J; Ropert, J -A; Rossé, B; Alvarez, C Rossi; Rosso, D; Rubio, B; Rudolph, D; Saillant, F; Şahin, E; Salomon, F; Salsac, M -D; Salt, J; Salvato, G; Sampson, J; Sanchis, E; Santos, C; Schaffner, H; Schlarb, M; Scraggs, D P; Seddon, D; Şenyiğit, M; Sigward, M -H; Simpson, G; Simpson, J; Slee, M; Smith, J F; Sona, P; Sowicki, B; Spolaore, P; Stahl, C; Stanios, T; Stefanova, E; Stézowski, O; Strachan, J; Suliman, G; Söderström, P -A; Tain, J L; Tanguy, S; Tashenov, S; Theisen, Ch; Thornhill, J; Tomasi, F; Toniolo, N; Touzery, R; Travers, B; Triossi, A; Tripon, M; Tun-Lanoë, K M M; Turcato, M; Unsworth, C; Ur, C A; Valiente-Dobon, J J; Vandone, V; Vardaci, E; Venturelli, R; Veronese, F; Veyssiere, Ch; Viscione, E; Wadsworth, R; Walker, P M; Warr, N; Weber, C; Weisshaar, D; Wells, D; Wieland, O; Wiens, A; Wittwer, G; Wollersheim, H J; Zocca, F; Zamfir, N V; Ziȩbliński, M; Zucchiatti, A

    2011-01-01

    The Advanced GAmma Tracking Array (AGATA) is a European project to develop and operate the next generation gamma-ray spectrometer. AGATA is based on the technique of gamma-ray energy tracking in electrically segmented high-purity germanium crystals. This technique requires the accurate determination of the energy, time and position of every interaction as a gamma ray deposits its energy within the detector volume. Reconstruction of the full interaction path results in a detector with very high efficiency and excellent spectral response. The realization of gamma-ray tracking and AGATA is a result of many technical advances. These include the development of encapsulated highly-segmented germanium detectors assembled in a triple cluster detector cryostat, an electronics system with fast digital sampling and a data acquisition system to process the data at a high rate. The full characterization of the crystals was measured and compared with detector-response simulations. This enabled pulse-shape analysis algorith...

  16. Extensive air showers generated by protons, nuclei, gamma-quanta and neutrinos at energy range 1 - 100 TeV

    Science.gov (United States)

    Sinitsyna, V. G.; Arsov, T. P.; Borisov, S. S.; Musin, F. I.; Nikolsky, S. I.; Mirzafatikhov, R. M.; Kasparov, G. M.; Sinitsyna, V. Y.; Platonov, G. F.

    2003-07-01

    Basic science: nuclear physics, physics of elementary particles and connected with them astrophysics and cosmology, has studied the structure of matter on micro and macro scales. Gamma-astronomy and neutrino-astronomy, are unique experimental possibilities to search for high-energy cosmic ray sources (1012 - 1014 eV). Evidence has already been obtained of metagalactic sources exceeding by 106 - 1012 times the power of gamma-quanta galactic sources. This data puts into doubt the assumption about the galactic origin of the observed very high energy cosmic radiation. The energy spectrum of the majority of known gamma-sources with energy 1012 - 1014 eV is harder than the proton and cosmic ray nuclei spectrum. The problem of observing extensive air showers generated by neutrinos is connected with the extremely small effective cross-section of inelastic collisions of neutrinos with nuclei. However, two facts allow a search for showers generated by neutrinos. The hadron cascade with primary energy of more than 1012 eV leaves the ground to atmosphere from depth of ~ 300 g/cm2 without essential loss of total energy in the hadron cascade. The Cherenkov radiation in the atmosphere from such hadron cascades will be observed at distances from the telescope of 7.5 km over an area more than 7 . 105 m2. This partially compensates for the small cross-section of inelastic neutrino collisions. RFBR, FNP, GNTP

  17. The role of plasma instabilities in the propagation of gamma-rays from distant Blazars

    Energy Technology Data Exchange (ETDEWEB)

    Saveliev, A.; Evoli, C.; Sigl, G. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2013-11-15

    The observation in the GeV band of distant blazars has been recently used to put constraints on the Extragalactic Background Light (EBL) and Extragalactic Magnetic Fields (EGMF). To support such claims one has to assume that the leptonic component of the electromagnetic cascade initiated by blazar gamma-rays is deflected away by strong enough EGMF, suppressing the signal in the Fermi window. Apart from magnetic fields, the development of such a cascade might be affected by plasma instabilities due to interactions with the ionized component of the Intergalactic Medium (IGM). In this paper we model the electromagnetic cascade through a Monte Carlo simulation in which both effects are taken into account separately, and we derive constraints on these scenarios from the combined Fermi-HESS data set. In the specific case of 1ES 0229+200 observations, we show that both explanations of the GeV flux suppression are compatible with the available data, specifically by assuming a magnetic field of B >or similar 10{sup -16} G or an IGM temperature of T cascades in the IGM.

  18. Pixelated gamma detector

    Energy Technology Data Exchange (ETDEWEB)

    Dolinsky, Sergei Ivanovich; Yanoff, Brian David; Guida, Renato; Ivan, Adrian

    2016-12-27

    A pixelated gamma detector includes a scintillator column assembly having scintillator crystals and optical transparent elements alternating along a longitudinal axis, a collimator assembly having longitudinal walls separated by collimator septum, the collimator septum spaced apart to form collimator channels, the scintillator column assembly positioned adjacent to the collimator assembly so that the respective ones of the scintillator crystal are positioned adjacent to respective ones of the collimator channels, the respective ones of the optical transparent element are positioned adjacent to respective ones of the collimator septum, and a first photosensor and a second photosensor, the first and the second photosensor each connected to an opposing end of the scintillator column assembly. A system and a method for inspecting and/or detecting defects in an interior of an object are also disclosed.

  19. Cascaded systems analysis of photon counting detectors

    Energy Technology Data Exchange (ETDEWEB)

    Xu, J.; Zbijewski, W.; Gang, G.; Stayman, J. W. [Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205 (United States); Taguchi, K.; Carrino, J. A. [Russell H. Morgan Department of Radiology, Johns Hopkins University, Baltimore, Maryland 21205 (United States); Lundqvist, M.; Fredenberg, E. [Philips Healthcare, Solna 171 41 (Sweden); Siewerdsen, J. H., E-mail: jeff.siewerdsen@jhu.edu [Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21205 (United States); Russell H. Morgan Department of Radiology, Johns Hopkins University, Baltimore, Maryland 21205 (United States)

    2014-10-15

    Purpose: Photon counting detectors (PCDs) are an emerging technology with applications in spectral and low-dose radiographic and tomographic imaging. This paper develops an analytical model of PCD imaging performance, including the system gain, modulation transfer function (MTF), noise-power spectrum (NPS), and detective quantum efficiency (DQE). Methods: A cascaded systems analysis model describing the propagation of quanta through the imaging chain was developed. The model was validated in comparison to the physical performance of a silicon-strip PCD implemented on an experimental imaging bench. The signal response, MTF, and NPS were measured and compared to theory as a function of exposure conditions (70 kVp, 1–7 mA), detector threshold, and readout mode (i.e., the option for coincidence detection). The model sheds new light on the dependence of spatial resolution, charge sharing, and additive noise effects on threshold selection and was used to investigate the factors governing PCD performance, including the fundamental advantages and limitations of PCDs in comparison to energy-integrating detectors (EIDs) in the linear regime for which pulse pileup can be ignored. Results: The detector exhibited highly linear mean signal response across the system operating range and agreed well with theoretical prediction, as did the system MTF and NPS. The DQE analyzed as a function of kilovolt (peak), exposure, detector threshold, and readout mode revealed important considerations for system optimization. The model also demonstrated the important implications of false counts from both additive electronic noise and charge sharing and highlighted the system design and operational parameters that most affect detector performance in the presence of such factors: for example, increasing the detector threshold from 0 to 100 (arbitrary units of pulse height threshold roughly equivalent to 0.5 and 6 keV energy threshold, respectively), increased the f{sub 50} (spatial

  20. Energy peak: back to the Galactic Center GeV gamma-ray excess

    CERN Document Server

    Kim, Doojin

    2015-01-01

    We propose a novel mechanism enabling us to have a continuum bump as a signature of gamma-ray excess in indirect detection experiments of dark matter (DM), postulating a generic dark sector having (at least) two DM candidates. With the assumption of non-zero mass gap between the two DM candidates, the heavier one directly communicates to the partner of the lighter one. Such a partner then decays into a lighter DM particle along with a dark "pion" or "axion-like" particle (ALP), which further decays into a pair of photons, via a more-than-one step cascade decay process. Since the cascade is initiated by the dark partner obtaining a non-trivial fixed boost factor, a continuum gamma-ray energy spectrum naturally arises. We apply the main idea to the energy spectrum of the GeV gamma-rays from around the Galactic Center (GC), and find that the relevant observational data is well-reproduced by the theory expectation predicted by the proposed mechanism. Remarkably, the relevant energy spectrum has a robust peak at h...

  1. Search for extended gamma ray emission in Markarian 421 using VERITAS observations

    CERN Document Server

    ,

    2014-01-01

    Very high energy (VHE: >100 GeV) gamma rays coming from AGN can pair-produce on the intergalactic background light generating an electromagnetic cascade. If the Intergalactic Magnetic Field (IGMF) is sufficiently strong, this cascade may result in an extended isotropic emission of photons around the source, or halo. Using VERITAS observations of the blazar Markarian 421, we search for extended emission by comparing the source angular distribution (${\\theta}^2$) from a quiescent period with one coming from a flare period, which can be considered as halo-free. ${\\chi}^2$ test showed no significant statistical differences between the samples, suggesting that the effect is either non-existent or too weak to be detected. We calculated upper limits for the extended flux considering different angle ranges, the most stringent being <8% of the Crab Nebulae flux (C.U), in the range $0\\deg \\leq {\\theta} \\leq 0.1\\deg$ .

  2. Measuring the Turbulent Cascade in the Solar Wind

    Science.gov (United States)

    MacBride, B. T.; Forman, M. A.; Smith, C. W.

    2006-12-01

    Kolmogorov's famous 4/5 law for the Navier-Stokes equation states that in isotropic hydrodynamic (HD) turbulence, the third moment of longitudinal velocity fluctuations at a spatial distance L is (4/5) ɛ ěrt L ěrt where ɛ is the turbulent energy cascade rate = heating rate per unit mass. A definite, signed, third moment is a fundamental property of the turbulent velocity fluctuations arising from the non-linear term in the Navier-Stokes equation, the only direct indicator that a cascade exists, the only measure of what direction that cascade takes (to smaller or larger spatial scales), and the truest indication of the cascade rate. The solar wind is MHD, however, and its turbulence is anisotropic. Dasso et al. (2005) perform a study on the anisotropy in the solar wind as a function of flow speed and find that there exists "quasi-two-dimensional" turbulence in low speed streams and a one dimensional "slab" structure in high speed flow. Politano and Pouquet (1998; PP) have derived an exact expression, valid in anisotropic situations, for the divergence with lag vector L of a certain vector third moment of the fluctuations in the Elsasser variables as a function of L. We perform an analysis of the third-order moment derived by PP. We use 8 years of ACE combine 64-s magnetic field and plasma measurements in variably defined subsets to compute the Elsasser variables in mean-field coordinates for different solar wind conditions (high/low wind speed, yearly, etc.). Most significantly, we attempt to separately resolve parallel and perpendicular cascades relative to the mean magnetic field. We find (1) the third moment structure functions are approximately proportional to lag as expected, (2) the inferred energy dissipation rate for outward-moving waves is larger than for inward-moving waves with many intervals showing evidence of an inverse cascade of the minority component, (3) the total energy-dissipation rate inferred by this method is frequently in disagreement

  3. Reducing Cascading Failure Risk by Increasing Infrastructure Network Interdependence

    Science.gov (United States)

    Korkali, Mert; Veneman, Jason G.; Tivnan, Brian F.; Bagrow, James P.; Hines, Paul D. H.

    2017-03-01

    Increased interconnection between critical infrastructure networks, such as electric power and communications systems, has important implications for infrastructure reliability and security. Others have shown that increased coupling between networks that are vulnerable to internetwork cascading failures can increase vulnerability. However, the mechanisms of cascading in these models differ from those in real systems and such models disregard new functions enabled by coupling, such as intelligent control during a cascade. This paper compares the robustness of simple topological network models to models that more accurately reflect the dynamics of cascading in a particular case of coupled infrastructures. First, we compare a topological contagion model to a power grid model. Second, we compare a percolation model of internetwork cascading to three models of interdependent power-communication systems. In both comparisons, the more detailed models suggest substantially different conclusions, relative to the simpler topological models. In all but the most extreme case, our model of a “smart” power network coupled to a communication system suggests that increased power-communication coupling decreases vulnerability, in contrast to the percolation model. Together, these results suggest that robustness can be enhanced by interconnecting networks with complementary capabilities if modes of internetwork failure propagation are constrained.

  4. TOPOLOGY AND CASCADING LINE OUTAGES IN POWER GRIDS

    Institute of Scientific and Technical Information of China (English)

    David L. PEPYNE

    2007-01-01

    Motivated by the small world network research of Watts & Strogatz, this paper studies relationships between topology and cascading line outages in electric power grids. Cascading line outages are a type of cascading collapse that can occur in power grids when the transmission network is congested. It is characterized by a self-sustaining sequence of line outages followed by grid breakup, which generally leads to widespread blackout. The main findings of this work are twofold: On one hand, the work suggests that topologies with more disorder in their interconnection topology tend to be robust with respect to cascading line outages in the sense of being able to support greater generation and demand levels than more regularly interconnected topologies. On the other hand, the work suggests that topologies with more disorder tend to be more fragile in that should a cascade get started, they tend to break apart after fewer outages than more regularly interconnected topologies. Thus, as has been observed in other complex networks, there appears to be a tradeoff between robustness and fragility.These results were established using synthetically generated power grid topologies and verified using the IEEE 57 bus and 188 bus power grid test cases.

  5. Reducing Cascading Failure Risk by Increasing Infrastructure Network Interdependence

    Science.gov (United States)

    Korkali, Mert; Veneman, Jason G.; Tivnan, Brian F.; Bagrow, James P.; Hines, Paul D. H.

    2017-01-01

    Increased interconnection between critical infrastructure networks, such as electric power and communications systems, has important implications for infrastructure reliability and security. Others have shown that increased coupling between networks that are vulnerable to internetwork cascading failures can increase vulnerability. However, the mechanisms of cascading in these models differ from those in real systems and such models disregard new functions enabled by coupling, such as intelligent control during a cascade. This paper compares the robustness of simple topological network models to models that more accurately reflect the dynamics of cascading in a particular case of coupled infrastructures. First, we compare a topological contagion model to a power grid model. Second, we compare a percolation model of internetwork cascading to three models of interdependent power-communication systems. In both comparisons, the more detailed models suggest substantially different conclusions, relative to the simpler topological models. In all but the most extreme case, our model of a “smart” power network coupled to a communication system suggests that increased power-communication coupling decreases vulnerability, in contrast to the percolation model. Together, these results suggest that robustness can be enhanced by interconnecting networks with complementary capabilities if modes of internetwork failure propagation are constrained. PMID:28317835

  6. Up and down cascades: three-dimensional magnetic field model.

    Science.gov (United States)

    Blanter, E M; Shnirman, M G; Le Mouël, J L

    2002-06-01

    In our previous works we already have proposed a two-dimensional model of geodynamo. Now we use the same approach to build a three-dimensional self-excited geodynamo model that generates a large scale magnetic field from whatever small initial field, using the up and down cascade effects of a multiscale turbulent system of cyclones. The multiscale system of turbulent cyclones evolves in six domains of an equatorial cylindrical layer of the core. The appearance of new cyclones is realized by two cascades: a turbulent direct cascade and an inverse cascade of coupling of similar cyclones. The interaction between the different domains is effected through a direct cascade parameter which is essential for the statistics of the long-life symmetry breaking. Generation of the secondary magnetic field results from the interaction of the components of the primary magnetic field with the turbulent cyclones. The amplification of the magnetic field is due to the transfer of energy from the turbulent helical motion to the generated magnetic field. The model demonstrates a phase transition through the parameter characterizing this energy transfer. In the supercritical domain we obtain long-term intervals of constant polarity (chrons) and quick reversals; relevant time constants agree with paleomagnetic observations. Possible application of the model to the study of the geometrical structure of the geomagnetic field (and briefly other planetary fields) is discussed.

  7. Critical assessment and ramifications of a purported marine trophic cascade

    Science.gov (United States)

    Grubbs, R. Dean; Carlson, John K; Romine, Jason G.; Curtis, Tobey H; McElroy, W. David; McCandless, Camilla T; Cotton, Charles F; Musick, John A.

    2016-01-01

    When identifying potential trophic cascades, it is important to clearly establish the trophic linkages between predators and prey with respect to temporal abundance, demographics, distribution, and diet. In the northwest Atlantic Ocean, the depletion of large coastal sharks was thought to trigger a trophic cascade whereby predation release resulted in increased cownose ray abundance, which then caused increased predation on and subsequent collapse of commercial bivalve stocks. These claims were used to justify the development of a predator-control fishery for cownose rays, the “Save the Bay, Eat a Ray” fishery, to reduce predation on commercial bivalves. A reexamination of data suggests declines in large coastal sharks did not coincide with purported rapid increases in cownose ray abundance. Likewise, the increase in cownose ray abundance did not coincide with declines in commercial bivalves. The lack of temporal correlations coupled with published diet data suggest the purported trophic cascade is lacking the empirical linkages required of a trophic cascade. Furthermore, the life history parameters of cownose rays suggest they have low reproductive potential and their populations are incapable of rapid increases. Hypothesized trophic cascades should be closely scrutinized as spurious conclusions may negatively influence conservation and management decisions.

  8. Understanding Low Energy Gamma Emission from Fission and Capture with DANCE

    Science.gov (United States)

    Wilburn, Grey; Couture, Aaron; Mosby, Shea

    2012-10-01

    Los Alamos National Laboratory's Detector for Advanced Neutron Capture Experiments (DANCE) consists of 160 barium fluoride (BaF2) detectors in a 4π array used to study cross-section measurements from neutron capture reactions. Further, recent studies have taken advantage of DANCE to study the gamma emission from fission, which is not well characterized. Neutron capture is studied because of its relevance to nuclear astrophysics (almost all elements heavier than iron are formed via neutron capture) and nuclear energy, where neutron capture is a poison in the reactor. Gamma ray cascades following neutron capture and fission include photons with energies between 100 keV and 10 MeV. DANCE uses a ^6LiH sphere to attenuate scattered neutrons, the primary background in DANCE. Unfortunately, it also attenuates low energy gamma rays. In order to quantify this effect and validate simulations, direct measurements of low energy gammas were made with a high purity germanium (HPGe) crystal. HPGe's allow for high resolution measurements of low energy gamma rays that are not possible using the BaF2 crystals. The results and their agreement with simulations will be discussed.

  9. $\\gamma\\gamma$ physics with the KLOE experiment

    CERN Document Server

    Archilli, F; Badoni, D; Balwierz, I; Bencivenni, G; Bini, C; Bloise, C; Bocci, V; Bossi, F; Branchini, P; Budano, A; Bulychjev, S A; Campana, P; Capon, G; Ceradini, F; Ciambrone, P; Czerwinski, E; Dane, E; De Lucia, E; De Robertis, G; De Santis, A; De Zorzi, G; Di Domenico, A; Di Donato, C; Domenici, D; Erriquez, O; Fanizzi, G; Felici, G; Fiore, S; Franzini, P; Gauzzi, P; Giovannella, S; Gonnella, F; Graziani, E; Happacher, F; Hoistad, B; Iarocci, E; Jacewicz, M; Johansson, T; Kulikov, V; Kupsc, A; Lee-Franzini, J; Loddo, F; Martemianov, M; Martini, M; Matsyuk, M; Messi, R; Miscetti, S; Morello, G; Moricciani, D; Moskal, P; Nguyen, F; Passeri, A; Patera, V; Longhi, I Prado; Ranieri, A; Santangelo, P; Sarra, I; Schioppa, M; Sciascia, B; Sciubba, A; Silarski, M; Taccini, C; Tortora, L; Venanzoni, G; Versaci, R; Wislicki, W; Wolke, M; Zdebik, J

    2011-01-01

    The processes $e^+e^-\\to e^+e^-X$, with $X$ being either the $\\eta$ meson or $\\pi^0\\pi^0$, are studied at DA$\\Phi$NE, with $e^+e^-$ beams colliding at $\\sqrt{s}\\simeq1$ GeV, below the $\\phi$ resonance peak. The data sample is from an integrated luminosity of 240 pb$^{-1}$, collected by the KLOE experiment without tagging of the outgoing $e^+e^-$. Preliminary results are presented on the observation of the $\\gamma\\gamma\\to\\eta$ process, with both $\\eta\\to\\pi^+\\pi^-\\pi^0$ and $\\eta\\to\\pi^0\\pi^0\\pi^0$ channels, and the evidence for $\\gamma\\gamma\\to\\pi^0\\pi^0$ production at low $\\pi^0\\pi^0$ invariant mass.

  10. Inference on Reliability in the Gamma and Inverted Gamma Distributions

    Directory of Open Access Journals (Sweden)

    Jungsoo Woo

    2012-07-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} We derive distributions of ratio for two independent gamma variables and two independent inverted gamma variables and then we observe the skewness of two ratio densities. We then consider inference on reliability in two independent gamma random variables and two independent inverted gamma random variables each having known shape parameters.

  11. Total Cross Section in $\\gamma\\gamma$ Collisions at LEP

    CERN Document Server

    Acciarri, M; Adriani, O; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, L; Balandras, A; Baldew, S V; Todorova-Nová, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Cucciarelli, S; Dai, T S; van Dalen, J A; D'Alessandro, R; De Asmundis, R; Déglon, P L; Degré, A; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Van Dierendonck, D N; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Dufournaud, D; Duinker, P; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ewers, A; Extermann, Pierre; Fabre, M; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hidas, P; Hirschfelder, J; Hofer, H; Holzner, G; Hoorani, H; Hou, S R; Hu, Y; Iashvili, I; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Khan, R A; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, J K; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Kopp, A; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Lee, H J; Le Goff, J M; Leiste, R; Levchenko, P M; Li Chuan; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Lugnier, L; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Marian, G; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Moulik, T; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Oulianov, A; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Paramatti, R; Park, H K; Park, I H; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pieri, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Postema, H; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Raven, G; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Rodin, J; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, Juan Antonio; Ruggiero, G; Rykaczewski, H; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Seganti, A; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Smith, B; Spillantini, P; Steuer, M; Stickland, D P; Stone, A; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S V; Suter, H; Swain, J D; Szillási, Z; Sztaricskai, T; Tang, X W; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Uchida, Y; Ulbricht, J; Valente, E; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Vorvolakos, A; Wadhwa, M

    2001-01-01

    The reaction e+e- -> e+e- gamma* gamma* -> e+e- hadrons for quasi-real photons is studied using data from root(s) = 183 GeV up to 202 GeV. Results on the total cross sections sigma(e+e- -> e+e- hadrons) and sigma(+e- gamma* gamma* -> e+e- hadrons) are given for the two-photon centre-of-mass energies 5 GeV < Wgammagamma < 185 GeV. The total cross section of two real photons is described by a Regge parametrisation. We observe a steeper rise with the two-photon centre-of-mass energy as compared to the hadron-hadron and the photon-proton cross sections. The data are also compared to the expectations of different theoretical models.

  12. 1,4-Diazepinone and pyrrolodiazepinone syntheses via homoallylic ketones from cascade addition of vinyl Grignard reagent to alpha-aminoacyl-beta-amino esters.

    Science.gov (United States)

    Iden, Hassan S; Lubell, William D

    2006-08-03

    [reaction: see text] 1,4-Diazepinones 5 and pyrrolodiazepinones 8 and 9 were synthesized from common homoallylic ketone precursors 4 prepared by copper-catalyzed cascade addition of a vinyl Grignard reagent to alpha-aminoacyl beta-amino esters 3. Nitrogen deprotection and intramolecular reductive amination yielded 1,4-diazepinones 5. Olefin oxidation, Boc removal, and intramolecular Paal-Knorr condensation gave pyrrolodiazepinones 8 and 9. X-ray structures of diazepinones 5c and 5d depicted dihedral angles about the alpha-amino acid moiety similar to those of the central residue in an ideal reverse gamma-turn.

  13. A Cascading Model Of An Active Magnetic Regenerator System

    DEFF Research Database (Denmark)

    Tahavori, M.; Filonenko, K.; Veje, C. T.;

    2016-01-01

    In recent years, significant amounts of studies have been done on modeling and analysis of active magnetic regenerators (AMRs). Depending on the AMR geometry and the magnetocaloric material being modeled, the AMR may not be able to provide the required performance demanded by practical applications....... Some AMR models in the literature predict high performance but with relatively low temperature spans at either end of the AMR. Therefore, they may not be sufficient for practical applications, such as providing the heat exchanger temperature spans required for residential and commercial space air...... conditioning. To remedy this, one solution is cascading of multiple single layer AMRs. In this work, a cascading AMR model is presented and studied. In a cascade configuration, N number of single layer AMRs are connected. The results show that higher hot and cold side temperature differences may be achieved...

  14. Robustness and perturbation in the modeled cascade heart rate variability

    Science.gov (United States)

    Lin, D. C.

    2003-03-01

    In this study, numerical experiments are conducted to examine the robustness of using cascade to describe the multifractal heart rate variability (HRV) by perturbing the hierarchical time scale structure and the multiplicative rule of the cascade. It is shown that a rigid structure of the multiple time scales is not essential for the multifractal scaling in healthy HRV. So long as there exists a tree structure for the multiplication to take place, a multifractal HRV and related properties can be captured by using the cascade. But the perturbation of the multiplicative rule can lead to a qualitative change. In particular, a multifractal to monofractal HRV transition can result after the product law is perturbed to an additive one at the fast time scale. We suggest that this explains the similar HRV scaling transition in the parasympathetic nervous system blockade.

  15. Robustness of Power-law Behavior in Cascading Failure Models

    CERN Document Server

    Sloothaak, F; Zwart, A P

    2016-01-01

    Inspired by reliability issues in electric transmission networks, we use a probabilistic approach to study the occurrence of large failures in a stylized cascading failure model. In this model, lines have random capacities that initially meet the load demands imposed on the network. Every single line failure changes the load distribution in the surviving network, possibly causing further lines to become overloaded and trip as well. An initial single line failure can therefore potentially trigger massive cascading effects, and in this paper we measure the risk of such cascading events by the probability that the number of failed lines exceeds a certain large threshold. Under particular critical conditions, the exceedance probability follows a power-law distribution, implying a significant risk of severe failures. We examine the robustness of the power-law behavior by exploring under which assumptions this behavior prevails.

  16. Irreversibility of the two-dimensional enstrophy cascade

    CERN Document Server

    Piretto,; Boffetta, G

    2016-01-01

    We study the time irreversibility of the direct cascade in two-dimensional turbulence by looking at the time derivative of the square vorticity along Lagrangian trajectories, a quantity which we call metenstrophy. By means of extensive numerical simulations we measure the time irreversibility from the asymmetry of the PDF of the metenstrophy and we find that it increases with the Reynolds number of the cascade, similarly to what found in three-dimensional turbulence. A detailed analysis of the different contributions to the enstrophy budget reveals a remarkable difference with respect to what observed for the direct cascade, in particular the role of the statistics of the forcing to determine the degree of irreversibility.

  17. Improving performance using cascade control and a Smith predictor.

    Science.gov (United States)

    Kaya, I

    2001-01-01

    Many investigations have been done on tuning proportional-integral-derivative (PID) controllers in single-input single-output (SISO) systems. However, only a few investigations have been carried out on tuning PID controllers in cascade control systems. In this paper, a new approach, namely the use of a Smith predictor in the outer loop of a cascade control system, is investigated. The method can be used in temperature control problems where the secondary part of the process (the inner loop) may have a negligible delay while the primary loop (the outer loop) has a time-delay. Two different approaches, including an autotuning method, to find the controller parameters are proposed. It is shown by some examples that the proposed structure as expected can provide better performance than conventional cascade control, a Smith predictor scheme or single feedback control system.

  18. Quasi-isotropic cascade in MHD turbulence with mean field

    CERN Document Server

    Grappin, Roland; Gürcan, Özgür

    2012-01-01

    We propose a phenomenological theory of incompressible magnetohydrodynamic turbulence in the presence of a strong large-scale magnetic field, which establishes a link between the known anisotropic models of strong and weak MHD turbulence We argue that the Iroshnikov-Kraichnan isotropic cascade develops naturally within the plane perpendicular to the mean field, while oblique-parallel cascades with weaker amplitudes can develop, triggered by the perpendicular cascade, with a reduced flux resulting from a quasi-resonance condition. The resulting energy spectrum $E(k_\\parallel,k_\\bot)$ has the same slope in all directions. The ratio between the extents of the inertial range in the parallel and perpendicular directions is equal to $b_{rms}/B_0$. These properties match those found in recent 3D MHD simulations with isotropic forcing reported in [R. Grappin and W.-C. M\\"uller, Phys. Rev. E \\textbf{82}, 26406 (2010)].

  19. Performance validation of a cascade control system through

    Directory of Open Access Journals (Sweden)

    A. Lakshmi Sangeetha

    2016-11-01

    Full Text Available The work analyzes the performance characteristics of a cascade control system when interconnected with various network architectures, such as Internet, mobile and wireless networks. The cascade control system consists of level and flow as primary and secondary variables, respectively. The web-enabled monitoring and control are realized using three techniques namely remote client–server, ActiveX-data socket and web publishing tool. Mobile network is established by interfacing the control system with a GSM modem which enables the monitoring of process parameters through mobile phones. The cascade control system is also monitored wirelessly from remote locations with advent of an indigenous wireless sensor node. The performance analysis proved that wireless monitoring may be considered as an effective alternate technique to the Internet-based communication especially for shorter distances.

  20. Cascaded Parametric Amplification for Highly Efficient Terahertz Generation

    CERN Document Server

    Ravi, Koustuban; Cirmi, Giovanni; Reichert, Fabian; Schimpf, Damian N; Muecke, Oliver D; Kaertner, Franz X

    2016-01-01

    A highly efficient, practical approach to high-energy terahertz (THz) generation based on spectrally cascaded optical parametric amplification (THz-COPA) is introduced. The THz wave initially generated by difference frequency generation between a strong narrowband optical pump and optical seed (0.1-10% of pump energy) kick-starts a repeated or cascaded energy down-conversion of pump photons. This helps to greatly surpass the quantum-defect efficiency and results in exponential growth of THz energy over crystal length. In cryogenically cooled periodically poled lithium niobate, energy conversion efficiencies >8% for 100 ps pulses are predicted. The calculations account for cascading effects, absorption, dispersion and laser-induced damage. Due to the coupled nonlinear interaction of multiple triplets of waves, THz-COPA exhibits physics distinct from conventional three-wave mixing parametric amplifiers. This in turn governs optimal phase-matching conditions, evolution of optical spectra as well as limitations o...

  1. Cascaded passive silicon microrings for large bandwidth slow light device

    Energy Technology Data Exchange (ETDEWEB)

    Li Yuntao; Hu Yingtao; Xiao Xi; Li Zhiyong; Yu Yude; Yu Jinzhong, E-mail: ytli@semi.ac.cn [State Key Laboratory of integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences, P. O. Box 912, Beijing 100083 (China)

    2011-02-01

    Slow light devices have important applications in the areas of data buffering, signal processing, and phased array antenna. Cascaded microring resonators structure can obtain large delay and also enhance the bandwidth, which was considered as a potential approach for future on-chip optical buffer. In this paper, we demonstrated a large bandwidth slow light device using cascaded Silicon-on-insulator (SOI) based microring resonators. With carefully designed the gap between the bus and the ring waveguides and the distances between the adjacent rings, a 57 ps group delay was observed and 83 Gbps maximum allowable bit rate is suggested according the measured 3 dB spectral bandwidth in the 8-stage cascaded microrings.

  2. Highly Loaded Fan by Using Tandem Cascade Rotor Blade

    Science.gov (United States)

    Hasegawa, Hiroaki; Suga, Shinya; Matsuoka, Akinori

    For axial flow compressors and fans in the aircraft engines higher pressure ratio is required in order to attain the high thrust engines. In this study, the fan with the tandem cascades was introduced to increase the fan pressure ratio. The use of tandem cascades in the fan allows savings in length and weight and therefore a compact fan could be built. The design of fan with tandem cascades and the fan testing were carried out to develop the high pressure ratio fan for the Air Turbo Ramjet (ATR) propulsion system. The ATR is a combined cycle engine which performs like a turbojet engine at subsonic speeds and a ramjet at supersonic speeds. In particular, high fan pressure ratio contributes to increase the engine thrust during subsonic flight at which the engine does not make use of ram effect. The results of the fan testing indicate that the pressure ratio of 2.2 is achieved in single stage fan.

  3. Cascaded VLSI Chips Help Neural Network To Learn

    Science.gov (United States)

    Duong, Tuan A.; Daud, Taher; Thakoor, Anilkumar P.

    1993-01-01

    Cascading provides 12-bit resolution needed for learning. Using conventional silicon chip fabrication technology of VLSI, fully connected architecture consisting of 32 wide-range, variable gain, sigmoidal neurons along one diagonal and 7-bit resolution, electrically programmable, synaptic 32 x 31 weight matrix implemented on neuron-synapse chip. To increase weight nominally from 7 to 13 bits, synapses on chip individually cascaded with respective synapses on another 32 x 32 matrix chip with 7-bit resolution synapses only (without neurons). Cascade correlation algorithm varies number of layers effectively connected into network; adds hidden layers one at a time during learning process in such way as to optimize overall number of neurons and complexity and configuration of network.

  4. Cascading failure analysis and restoration strategy in an interdependent network

    Science.gov (United States)

    Hong, Sheng; Lv, Chuan; Zhao, Tingdi; Wang, Baoqing; Wang, Jianghui; Zhu, Juxing

    2016-05-01

    In modern society, many infrastructures are interdependent owing to functional and logical relations among components in different systems. These networked infrastructures can be modeled as interdependent networks. In the real world, different networks carry different traffic loads whose values are dynamic and stem from the load redistribution in the same network and disturbance from the interdependent network. Interdependency makes interdependent networks so fragile that even a slight initial disturbance may lead to a cascading failure of the entire systems. In this paper, interdependencies among networks are modeled and a failure cascade process is studied considering their effects on failure propagation. Meanwhile, an in-process restoration strategy after the initial failure is investigated. The restoration effects depend strongly on the trigger timing, restoration probability and priority of the restoration actions along with the additional disturbances. Our findings highlight the necessity to decrease the large-scale cascading failure by structuring and managing an interdependent network reasonably.

  5. Bearing-Only Formation Control for Cascade Multirobots

    Directory of Open Access Journals (Sweden)

    Qing Han

    2016-01-01

    Full Text Available A new formation control method is proposed, which is used to queue multirobots in a single-direction cascade structure. In the cascade formation, each robot is a follower for the previous robot and a leader for the next robot, and the robots in the middle act as both leader and follower. The follower robot can only observe the bearing information of the leader robot. The observability of the cascade leader-follower formation is studied, which shows that the bearing-only observation meets the observability conditions required for the nonlinear system. Based on the bearing-only observations, the unscented Kalman filter (UKF is employed for the state estimation of the leader and the follower robots at all levels, which enables the real-time movement control of the follower robots via the input-output feedback control. Simulation results demonstrate that the proposed approach can efficiently control the formation of multirobots as desired.

  6. Cascaded effects of spatial adaptation in the early visual system.

    Science.gov (United States)

    Dhruv, Neel T; Carandini, Matteo

    2014-02-05

    Virtually all stages of the visual system exhibit adaptation: neurons adjust their responses based on the recent stimulus history. While some of these adjustments occur at specific stages, others may be inherited from earlier stages. How do adaptation effects cascade along the visual system? We measured spatially selective adaptation at two successive stages in the mouse visual system: visual thalamus (LGN) and primary visual cortex (V1). This form of adaptation affected both stages but in drastically different ways: in LGN it only changed response gain, while in V1 it also shifted spatial tuning away from the adaptor. These effects, however, are reconciled by a simple model whereby V1 neurons summate LGN inputs with a fixed, unadaptable weighting profile. These results indicate that adaptation effects cascade through the visual system, that this cascading can shape selectivity, and that the rules of integration from one stage to the next are not themselves adaptable.

  7. Gamma-ray-selected AGN

    Science.gov (United States)

    Giommi, Paolo

    2016-08-01

    The gamma-ray band is the most energetic part of the electromagnetic spectrum. As such it is also where selection effects are most severe, as it can only be reached by the most extreme non-thermal AGN. Blazars, with their emission dominated by non-thermal blue-shifted radiation arising in a relativistic jet pointed in the direction of the observer, naturally satisfy this though requirement. For this reason, albeit these sources are intrisically very rare (orders of magnitude less abundant than radio quiet AGN of the same optical magnitude) they almost completely dominate the extragalactic gamma-ray and very high energy sky. I will discuss the emission of different types of blazars and the selection effects that are at play in the gamma-ray band based on recent results from the current generation of gamma-ray astronomy satellites, ground-based Cherenkov telescopes, and Monte Carlo simulations.

  8. The GAMMA-400 Space Experiment

    Science.gov (United States)

    Bongi, M.

    2014-06-01

    GAMMA-400 is a new space experiment which will study gamma rays and cosmic rays from about 100 MeV up to some TeVs. The proposed instrument has an angular resolution ˜ 0.1 degrees at 10 GeV and better than ˜ 0.02 degrees above 100 GeV, and an energy resolution ˜ 1% at E > 100 GeV for gamma rays. With these characteristics the experiment will be able to contribute to the search for signatures of Dark Matter, and to the study of Galactic and ex-tragalactic gamma sources and diffuse emission. A large segmented calorimeter more than 25 X0 deep will allow the study of high-energy electrons, and the measurement of the flux of protons and nuclei up to the "knee" region.

  9. Pulsar wind model of close massive gamma-ray binaries: The influence of geometry in the pulsar wind zone processes

    CERN Document Server

    Sierpowska-Bartosik, Agnieszka

    2008-01-01

    Several gamma-ray binaries have been recently detected by the High-Energy Stereoscopy Array (H.E.S.S.) and the Major Atmospheric Imaging Cerenkov (MAGIC) telescope. In at least two cases, their nature is unknown, since a distinctive, final observational feature for a black hole or a pulsar compact object companion is still missing. In this paper we aim to provide the details of a theoretical model of close gamma-ray binaries containing a young energetic pulsar as compact object. This model includes a detailed account of the system geometry, the angular dependence of processes such as Klein-Nishina inverse Compton and gamma-gamma absorption, and a Monte Carlo simulation of cascading. We present and derive the used formulae and give all details about their numerical implementation, particularly, on the computation of cascades. In this model, emphasis is put in the processes occurring in the pulsar wind zone of the binary, i.e., the region between the pulsar and the shock in between of the two stars, since as we...

  10. MATCASC: A tool to analyse cascading line outages in power grids

    CERN Document Server

    Koç, Yakup; Araujo, Nuno A M; Warnier, Martijn

    2013-01-01

    Blackouts in power grids typically result from cascading failures. The key importance of the electric power grid to society encourages further research into sustaining power system reliability and developing new methods to manage the risks of cascading blackouts. Adequate software tools are required to better analyze, understand, and assess the consequences of the cascading failures. This paper presents MATCASC, an open source MATLAB based tool to analyse cascading failures in power grids. Cascading effects due to line overload outages are considered. The applicability of the MATCASC tool is demonstrated by assessing the robustness of IEEE test systems and real-world power grids with respect to cascading failures.

  11. One-dimensional hydrodynamic model generating a turbulent cascade

    Science.gov (United States)

    Matsumoto, Takeshi; Sakajo, Takashi

    2016-05-01

    As a minimal mathematical model generating cascade analogous to that of the Navier-Stokes turbulence in the inertial range, we propose a one-dimensional partial-differential-equation model that conserves the integral of the squared vorticity analog (enstrophy) in the inviscid case. With a large-scale random forcing and small viscosity, we find numerically that the model exhibits the enstrophy cascade, the broad energy spectrum with a sizable correction to the dimensional-analysis prediction, peculiar intermittency, and self-similarity in the dynamical system structure.

  12. Feigenbaum Cascade of Discrete Breathers in a Model of DNA

    CERN Document Server

    Maniadis, P; Bishop, A R; Rasmussen, K \\O

    2010-01-01

    We demonstrate that period-doubled discrete breathers appear from the anti-continuum limit of the driven Peyrard-Bishop-Dauxois model of DNA. These novel breathers result from a stability overlap between sub-harmonic solutions of the driven Morse oscillator. Sub-harmonic breathers exist whenever a stability overlap is present within the Feigenbaum cascade to chaos and therefore an entire cascade of such breathers exists. This phenomenon is present in any driven lattice where the on-site potential admits sub-harmonic solutions. In DNA these breathers may have ramifications for cellular gene expression.

  13. Cascade Control of Magnetic Levitation with Sliding Modes

    Directory of Open Access Journals (Sweden)

    Eroğlu Yakup

    2016-01-01

    Full Text Available The effectiveness and applicability of magnetic levitation systems need precise feedback control designs. A cascade control approach consisting of sliding mode control plus sliding mode control (SMC plus SMC is designed to solve position control problem and to provide a high control performance and robustness to the magnetic levitation plant. It is shown that the SMC plus SMC cascade controller is able to eliminate the effects of the inductance related uncertainties of the electromagnetic coil of the plant and achieve a robust and precise position control. Experimental and numerical results are provided to validate the effectiveness and feasibility of the method.

  14. Maximizing the Spread of Cascades Using Network Design

    CERN Document Server

    Sheldon, Daniel; Elmachtoub, Adam N; Finseth, Ryan; Sabharwal, Ashish; Conrad, Jon; Gomes, Carla P; Shmoys, David; Allen, William; Amundsen, Ole; Vaughan, William

    2012-01-01

    We introduce a new optimization framework to maximize the expected spread of cascades in networks. Our model allows a rich set of actions that directly manipulate cascade dy- namics by adding nodes or edges to the net- work. Our motivating application is one in spatial conservation planning, where a cas- cade models the dispersal of wild animals through a fragmented landscape. We propose a mixed integer programming (MIP) formu- lation that combines elements from network design and stochastic optimization. Our ap- proach results in solutions with stochastic op- timality guarantees and points to conserva- tion strategies that are fundamentally dier- ent from naive approaches.

  15. Spatial Organization of Enzyme Cascade on a DNA Origami Nanostructure.

    Science.gov (United States)

    Fu, Jinglin; Li, Tianran

    2017-01-01

    Self-assembled DNA nanostructures hold great promise to organize multi-enzyme systems with the precise control of the geometric arrangements. Enzymes modified with single-stranded DNA anchors are assembled onto the DNA origami tiles by hybridizing with the corresponding complementary strands displayed on the surface of the DNA nanostructures. Here, we describe a protocol of assembling a two-enzyme cascade on a discrete, rectangular DNA origami tile, where the distance between enzymes is precisely controlled for investigating the distance-dependent cascade activities.

  16. Aerodynamic Optimum Design of Transonic Turbine Cascades Using Genetic Algorithms

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    This paper presents an aerodynamic optimum design method for transonic turbine cascades based on the Genetic Algorithms coupled to the inviscid flow Euler Solver and the boundary-layer calculation.The Genetic Algorithms control the evolution of a population of cascades towards an optimum design.The fitness value of each string is evaluated using the flow solver.The design procedure has been developed and the behavior of the genetic algorithms has been tested.The objective functions of the design examples are the minimum mean-square deviation between the aimed pressure and computed pressure and the minimum amount of user expertise.

  17. Quantifying efficient information transduction of biochemical signaling cascades

    CERN Document Server

    Tsuruyama, Tatsuaki

    2016-01-01

    Cells can be considered as systems that utilize changes in thermodynamic entropy as information. Therefore, they serve as useful models for investigating the relationships between entropy production and information transmission, i.e., signal transduction. Based on the hypothesis that cells apply a chemical reaction cascade for the most efficient transduction of information, we adopted a coding design that minimizes the number of bits per concentration of molecules that are employed for information transduction. As a result, the average rate of entropy production is uniform across all cycles in a cascade reaction. Thus, the entropy production rate can be a valuable measure for the quantification of intracellular signal transduction.

  18. Protein-DNA computation by stochastic assembly cascade

    CERN Document Server

    Bar-Ziv, Roy; Libchaber, Albert; 10.1073/pnas.162369099

    2010-01-01

    The assembly of RecA on single-stranded DNA is measured and interpreted as a stochastic finite-state machine that is able to discriminate fine differences between sequences, a basic computational operation. RecA filaments efficiently scan DNA sequence through a cascade of random nucleation and disassembly events that is mechanistically similar to the dynamic instability of microtubules. This iterative cascade is a multistage kinetic proofreading process that amplifies minute differences, even a single base change. Our measurements suggest that this stochastic Turing-like machine can compute certain integral transforms.

  19. Coherent vortex structures and 3D enstrophy cascade

    CERN Document Server

    Dascaliuc, R

    2011-01-01

    Existence of 2D enstrophy cascade in a suitable mathematical setting, and under suitable conditions compatible with 2D turbulence phenomenology, is known both in the Fourier and in the physical scales. The goal of this paper is to show that the same geometric condition preventing the formation of singularities - 1/2-H\\"older coherence of the vorticity direction - coupled with a suitable condition on a modified Kraichnan scale, and under a certain modulation assumption on evolution of the vorticity, leads to existence of 3D enstrophy cascade in physical scales of the flow.

  20. One-dimensional hydrodynamic model generating turbulent cascade

    CERN Document Server

    Matsumoto, Takeshi

    2016-01-01

    As a minimal mathematical model generating cascade analogous to that of the Navier-Stokes turbulence in the inertial range, we propose a one-dimensional partial-differential-equation model that conserves the integral of the squared vorticity analogue (enstrophy) in the inviscid case. With a large-scale forcing and small viscosity, we find numerically that the model exhibits the enstrophy cascade, the broad energy spectrum with a sizable correction to the dimensional-analysis prediction, peculiar intermittency and self-similarity in the dynamical system structure.

  1. Stability and Stabilization of Block-cascading Switched Linear Systems

    Institute of Scientific and Technical Information of China (English)

    Ya-Hong Zhu; Dai-Zhan Cheng

    2006-01-01

    The main purpose of this paper is to investigate the problem of quadratic stability and stabilization in switched linear systems using reducible Lie algebra. First, we investigate the structure of all real invariant subspaces for a given linear system. The result is then used to provide a comparable cascading form for switching models. Using the commoncascading form, a common quadratic Lyapunov function is (QLFs) is explored by finding common QLFs of diagonal blocks.In addition, a cascading Quaker Lemma is proved. Combining it with stability results, the problem of feedback stabilization for a class of switched linear systems is solved.

  2. Applications of absorption spectroscopy using quantum cascade lasers.

    Science.gov (United States)

    Zhang, Lizhu; Tian, Guang; Li, Jingsong; Yu, Benli

    2014-01-01

    Infrared laser absorption spectroscopy (LAS) is a promising modern technique for sensing trace gases with high sensitivity, selectivity, and high time resolution. Mid-infrared quantum cascade lasers, operating in a pulsed or continuous wave mode, have potential as spectroscopic sources because of their narrow linewidths, single mode operation, tunability, high output power, reliability, low power consumption, and compactness. This paper reviews some important developments in modern laser absorption spectroscopy based on the use of quantum cascade laser (QCL) sources. Among the various laser spectroscopic methods, this review is focused on selected absorption spectroscopy applications of QCLs, with particular emphasis on molecular spectroscopy, industrial process control, combustion diagnostics, and medical breath analysis.

  3. Rate equation modelling and investigation of quantum cascade detector characteristics

    Science.gov (United States)

    Saha, Sumit; Kumar, Jitendra

    2016-10-01

    A simple precise transport model has been proposed using rate equation approach for the characterization of a quantum cascade detector. The resonant tunneling transport is incorporated in the rate equation model through a resonant tunneling current density term. All the major scattering processes are included in the rate equation model. The effect of temperature on the quantum cascade detector characteristics has been examined considering the temperature dependent band parameters and the carrier scattering processes. Incorporation of the resonant tunneling process in the rate equation model improves the detector performance appreciably and reproduces the detector characteristics within experimental accuracy.

  4. Cascade adaptive control of uncertain unified chaotic systems

    Institute of Scientific and Technical Information of China (English)

    Wei Wei; Li Dong-Hai; Wang Jing

    2011-01-01

    The chaos control of uncertain unified chaotic systems is considered. Cascade adaptive control approach with only one control input is presented to stabilize states of the uncertain unified chaotic system at the zero equilibrium point.Since an adaptive controller based on dynamic compensation mechanism is employed, the exact model of the unified chaotic system is not necessarily required.By choosing appropriate controller parameters, chaotic phenomenon can be suppressed and the response speed is tunable. Sufficient condition for the asymptotic stability of the approach is derived. Numerical simulation results confirm that the cascade adaptive control approach with only one control signal is valid in chaos control of uncertain unified chaotic systems.

  5. TEMPORAL OPTICAL SOLITONS VIA MULTISTEP x(2) CASCADING

    Institute of Scientific and Technical Information of China (English)

    HUANG GUO-XIANG

    2001-01-01

    We consider a multistep X(2) cascading for light pulses with the dispersion of the system taken into account. Using the method of multiple scales we derive a set of coupled envelope equations governing the nonlinear evolution of the fundamental, second and third harmonic waves involved simultaneously in two nonlinear optical processes, i.e. second harmonic generation and sum frequency mixing. We show that three-wave temporal optical solitons are possible in three- and four-step cascading in the presence of a group-velocity mismatch between different pulses.

  6. Cascading Failures in Networks: Inference, Intervention and Robustness to WMDs

    Science.gov (United States)

    2016-08-01

    8725 John J. Kingman Road, MS 6201 Fort Belvoir, VA 22060-6201 T E C H N IC A L R E P O R T DTRA-TR-16-83 Cascading Failures in Networks ...aspect of this collection of information, including suggestions for reducing this burden to Department of Defense, Washington Headquarters Services ...Austin   Project  Title:  Cascading  Failures  in   Networks :  Inference,  Intervention  and  Robustness  to   WMDs   What  are  the  major  goals  of

  7. Gamma Astrometric Measurement Experiment

    Science.gov (United States)

    Gai, M.; Lattanzi, M. G.; Ligori, S.; Loreggia, D.; Vecchiato, A.

    GAME aims at the measurement of gravitational deflection of the light by the Sun, by an optimised telescope on board a small class satellite. The targeted precision on the gamma parameter of the Parametrised Post-Newtonian formulation of General Relativity is below 10-6, i.e. one to two orders of magnitude better than the best current results. Such precision is suitable to detect possible deviations from the unity value, associated to generalised Einstein models for gravitation, with potentially huge impacts on the cosmological distribution of dark matter and dark energy. The measurement principle is based on differential astrometry. The observations also allow additional scientific objectives related to tests of General Relativity and to the study of exo-planetary systems. The instrument concept is based on a dual field, multiple aperture Fizeau interferometer, observing simultaneously two regions close to the Solar limb. The diluted optics achieves efficient rejection of the solar radiation, with good angular resolution on the science targets. We describe the science motivation, the proposed mission implementation and the expected performance.

  8. Notes on the gamma kernel

    DEFF Research Database (Denmark)

    Barndorff-Nielsen, Ole E.

    The density function of the gamma distribution is used as shift kernel in Brownian semistationary processes modelling the timewise behaviour of the velocity in turbulent regimes. This report presents exact and asymptotic properties of the second order structure function under such a model......, and relates these to results of von Karmann and Horwath. But first it is shown that the gamma kernel is interpretable as a Green’s function....

  9. Dark Matter Search Perspectives with GAMMA-400

    CERN Document Server

    Moiseev, A A; Adriani, O; Aptekar, R L; Arkhangelskaja, I V; Arkhangelskiy, A I; Avanesov, G A; Bergstrom, L; Boezio, M; Bonvicini, V; Boyarchuk, K A; Dogiel, V A; Gusakov, Yu V; Fradkin, M I; Fuglesang, Ch; Hnatyk, B I; Kachanov, V A; Kaplin, V A; Kheymits, M D; Korepanov, V; Larsson, J; Leonov, A A; Longo, F; Maestro, P; Marrocchesi, P; Mazets, E P; Mikhailov, V V; Mocchiutti, E; Mori, N; Moskalenko, I; Naumov, P Yu; Papini, P; Pearce, M; Picozza, P; Runtso, M F; Ryde, F; Sparvoli, R; Spillantini, P; Suchkov, S I; Tavani, M; Topchiev, N P; Vacchi, A; Vannuccini, E; Yurkin, Yu T; Zampa, N; Zarikashvili, V N; Zverev, V G

    2013-01-01

    GAMMA-400 is a future high-energy gamma-ray telescope, designed to measure the fluxes of gamma-rays and cosmic-ray electrons + positrons, which can be produced by annihilation or decay of dark matter particles, and to survey the celestial sphere in order to study point and extended sources of gamma-rays, measure energy spectra of Galactic and extragalactic diffuse gamma-ray emission, gamma-ray bursts, and gamma-ray emission from the Sun. GAMMA-400 covers the energy range from 100 MeV to ~3000 GeV. Its angular resolution is ~0.01 deg(Eg > 100 GeV), and the energy resolution ~1% (Eg > 10 GeV). GAMMA-400 is planned to be launched on the Russian space platform Navigator in 2019. The GAMMA-400 perspectives in the search for dark matter in various scenarios are presented in this paper

  10. Asymmetric function of theta and gamma activity in syllable processing: an intra-cortical study

    Directory of Open Access Journals (Sweden)

    Benjamin eMorillon

    2012-07-01

    Full Text Available Low-gamma (25-45 Hz and theta (4-8 Hz oscillations are proposed to underpin the integration of phonemic and syllabic information, respectively. How these two scales of analysis split functions across hemispheres is unclear. We analyzed cortical responses from an epileptic patient with a rare bilateral electrode implantation (stereotactic EEG in primary (A1/BA41 and A2/BA42 and association auditory cortices (BA22. Using time-frequency analyses, we confirmed the dominance of a 5-6 Hz theta activity in right and of a low-gamma (25-45 Hz activity in left primary auditory cortices (A1/A2, during both resting state and syllable processing. We further detected high-theta (7-8 Hz resting activity in left primary, but also associative auditory regions. In left BA22, its phase correlated with high-gamma induced power. Such a hierarchical relationship across theta and gamma frequency bands (theta/gamma phase-amplitude coupling could index the process by which the neural code shifts from stimulus feature- to phonological- encoding, and is associated with the transition from evoked to induced power responses. These data suggest that theta and gamma activity in right and left auditory cortices bear different functions. They support a scheme where slow parsing of the acoustic information dominates in right-hemisphere at a syllabic (5-6 Hz rate, and left auditory cortex exhibits a more complex cascade of oscillations, reflecting the possible extraction of transient acoustic cues at a fast (~25-45 Hz rate, subsequently integrated at a slower, e.g. syllabic one. Slow oscillations could functionally participate to speech processing by structuring gamma activity in left BA22, where abstract percepts emerge.

  11. Status of development of the Gamma Ray Energy Tracking Array (GRETA)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, I.Y.; Schmid, G.J.; Vetter, K. [Lawrence Berkeley National Lab., CA (United States)] [and others

    1996-12-31

    The current generation of large gamma-ray detector arrays, Gammasphere, Eurogam and GASP, are based on modules of Compton suppressed Ge detectors. Due to the solid angle occupied by the Compton shields and to gamma rays escaping the detector, the total peak efficiency of such a design is limited to about 20% for a 1.3 MeV gamma ray. A shell consisting of closely packed Ge detectors has been suggested as the solution to the efficiency limitation. In this case, the entire solid angle is covered by Ge detectors, and by adding the signal from neighboring detectors, the escaped energy is recovered and much higher efficiency can be achieved (e.g. 60% for a 1.3 MeV gamma ray). However, for high multiplicity cascades, the summing of two gamma rays hitting neighboring detectors reduces the efficiency and increases the background. In order to reduce this summing, a large number of detectors is required. For example, with a multiplicity of 25, one needs about 1500 detectors to keep the probability of false summing below 10% and the cost of such a detector array will be prohibitive. Rather than such an approach, the authors are developing a new concept for a gamma-ray array; a shell of closely-packed Ge detectors consisting of 100-200 highly-segmented elements. The high granularity of the segmented Ge detector enables the authors to resolve each of the scattering interactions and determine its position and energy. A tracking algorithm, using the position and energy information, will then identify the interactions belonging to a particular gamma ray and its energy is obtained by summing only these interactions. Such an array can reach a total efficiency about 60%, with a resolving power 1000 times higher than that of current arrays.

  12. New evaluation of photon production for JEFF-3

    Science.gov (United States)

    Ravaux, S.; Bernard, D.; Santamarina, A.

    2013-03-01

    In this work, new gamma production evaluations are proposed for JEFF-3 for crucial nuclei for power reactors and Jules Horowitz Reactor: Fe, Ag, In, Cd and Gd. We specifically work on two nuclear reactions: the inelastic scattering and the radiative capture. We performed gamma production multiplicities, angular distributions and energy spectrum for incident neutron energies between 10-11 and 20 MeV by simulating the whole intranuclear gamma cascade. For this simulation, the discrete part of the nuclei level schemes came from the RIPL2.0 library and the latest EGAF measurements carried out at Budapest facility. The EGAF measurements are available in the adopted IAEA library. The continuum level scheme part has been estimated with a level density model: the Gilbert-Cameron model and a strength function model: the Generalized Lorentzian model. Then, the gamma cascade has been simulated using TALYS which is a nuclear reaction modeling code.

  13. Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC).

    Science.gov (United States)

    Ivanov, Vladimir N; Hei, Tom K

    2014-12-01

    Ionizing radiation alone or in combination with chemotherapy is the main treatment modality for brain tumors including glioblastoma. Adult neurons and astrocytes demonstrate substantial radioresistance; in contrast, human neural stem cells (NSC) are highly sensitive to radiation via induction of apoptosis. Irradiation of tumor cells has the potential risk of affecting the viability and function of NSC. In this study, we have evaluated the effects of irradiated glioblastoma cells on viability, proliferation and differentiation potential of non-irradiated (bystander) NSC through radiation-induced signaling cascades. Using media transfer experiments, we demonstrated significant effects of the U87MG glioblastoma secretome after gamma-irradiation on apoptosis in non-irradiated NSC. Addition of anti-TRAIL antibody to the transferred media partially suppressed apoptosis in NSC. Furthermore, we observed a dramatic increase in the production and secretion of IL8, TGFβ1 and IL6 by irradiated glioblastoma cells, which could promote glioblastoma cell survival and modify the effects of death factors in bystander NSC. While differentiation of NSC into neurons and astrocytes occurred efficiently with the corresponding differentiation media, pretreatment of NSC for 8 h with medium from irradiated glioblastoma cells selectively suppressed the differentiation of NSC into neurons, but not into astrocytes. Exogenous IL8 and TGFβ1 increased NSC/NPC survival, but also suppressed neuronal differentiation. On the other hand, IL6 was known to positively affect survival and differentiation of astrocyte progenitors. We established a U87MG neurosphere culture that was substantially enriched by SOX2(+) and CD133(+) glioma stem-like cells (GSC). Gamma-irradiation up-regulated apoptotic death in GSC via the FasL/Fas pathway. Media transfer experiments from irradiated GSC to non-targeted NSC again demonstrated induction of apoptosis and suppression of neuronal differentiation of NSC. In

  14. Gamma-ray Pulsar Revolution

    CERN Document Server

    Caraveo, Patrizia A

    2013-01-01

    Isolated Neutron Stars (INSs) were the first sources identified in the field of high-energy gamma-ray astronomy. At first, in the 70s, there were only two identified sources, the Crab and Vela pulsars. However, although few in number, these objects were crucial in establishing the very concept of a gamma-ray source. Moreover, they opened up significant discovery space both in the theoretical and phenomenological fronts. The need to explain the copious gamma-ray emission of these pulsars led to breakthrough developments in understanding the structure and physics of neutron star magnetospheres. In parallel, the 20-year-long chase to understand the nature of Geminga unveiled the existence of a radio-quiet, gamma-ray-emitting, INS, adding a new dimension to the INS family. Today we are living through an extraordinary time of discovery. The current generation of gamma-ray detectors has vastly increased the population of known of gamma-ray-emitting neutron stars. The 100 mark was crossed in 2011 and we are now appr...

  15. Displacement cascades and defect annealing in tungsten, Part II: Object kinetic Monte Carlo simulation of tungsten cascade aging

    Energy Technology Data Exchange (ETDEWEB)

    Nandipati, Giridhar, E-mail: giridhar.nandipati@pnnl.gov [Pacific Northwest National Laboratory, Richland, WA (United States); Setyawan, Wahyu; Heinisch, Howard L. [Pacific Northwest National Laboratory, Richland, WA (United States); Roche, Kenneth J. [Pacific Northwest National Laboratory, Richland, WA (United States); Department of Physics, University of Washington, Seattle, WA 98195 (United States); Kurtz, Richard J. [Pacific Northwest National Laboratory, Richland, WA (United States); Wirth, Brian D. [University of Tennessee, Knoxville, TN (United States)

    2015-07-15

    The results of object kinetic Monte Carlo (OKMC) simulations of the annealing of primary cascade damage in bulk tungsten using a comprehensive database of cascades obtained from molecular dynamics (Setyawan et al.) are described as a function of primary knock-on atom (PKA) energy at temperatures of 300, 1025 and 2050 K. An increase in SIA clustering coupled with a decrease in vacancy clustering with increasing temperature, in addition to the disparate mobilities of SIAs versus vacancies, causes an interesting effect of temperature on cascade annealing. The annealing efficiency (the ratio of the number of defects after and before annealing) exhibits an inverse U-shape curve as a function of temperature. The capabilities of the newly developed OKMC code KSOME (kinetic simulations of microstructure evolution) used to carry out these simulations are described.

  16. Displacement cascades and defect annealing in tungsten, Part II: Object kinetic Monte Carlo Simulation of Tungsten Cascade Aging

    Energy Technology Data Exchange (ETDEWEB)

    Nandipati, Giridhar; Setyawan, Wahyu; Heinisch, Howard L.; Roche, Kenneth J.; Kurtz, Richard J.; Wirth, Brian D.

    2015-07-01

    The results of object kinetic Monte Carlo (OKMC) simulations of the annealing of primary cascade damage in bulk tungsten using a comprehensive database of cascades obtained from molecular dynamics (Setyawan et al.) are described as a function of primary knock-on atom (PKA) energy at temperatures of 300, 1025 and 2050 K. An increase in SIA clustering coupled with a decrease in vacancy clustering with increasing temperature, in addition to the disparate mobilities of SIAs versus vacancies, causes an interesting effect of temperature on cascade annealing. The annealing efficiency (the ratio of the number of defects after and before annealing) exhibits an inverse U-shape curve as a function of temperature. The capabilities of the newly developed OKMC code KSOME (kinetic simulations of microstructure evolution) used to carry out these simulations are described.

  17. Search for an extended VHE gamma-ray emission from Mrk 421 and Mrk 501 with the MAGIC Telescope

    CERN Document Server

    Aleksić, J; Antoranz, P; Backes, M; Baixeras, C; Barrio, J A; Bastieri, D; González, J Becerra; Bednarek, W; Berdyugin, A; Berger, K; Bernardini, E; Biland, A; Blanch, O; Bock, R K; Bonnoli, G; Bordas, P; Tridon, D Borla; Bosch-Ramon, V; Bose, D; Braun, I; Bretz, T; Britzger, D; Camara, M; Carmona, E; Carosi, A; Colin, P; Commichau, S; Contreras, J L; Cortina, J; Costado, M T; Covino, S; Dazzi, F; De Angelis, A; del Pozo, E De Cea; Reyes, R De los; De Lotto, B; De Maria, M; De Sabata, F; Mendez, C Delgado; Doert, M; Domínguez, A; Prester, D Dominis; Dorner, D; Doro, M; Elsaesser, D; Errando, M; Ferenc, D; Fonseca, M V; Font, L; López, R J García; Garczarczyk, M; Gaug, M; Godinovic, N; Hadasch, D; Herrero, A; Hildebrand, D; Höhne-Mönch, D; Hose, J; Hrupec, D; Hsu, C C; Jogler, T; Klepser, S; Krähenbühl, T; Kranich, D; La Barbera, A; Laille, A; Leonardo, E; Lindfors, E; Lombardi, S; Longo, F; López, M; Lorenz, E; Majumdar, P; Maneva, G; Mankuzhiyil, N; Mannheim, K; Maraschi, L; Mariotti, M; Martínez, M; Mazin, D; Meucci, M; Miranda, J M; Mirzoyan, R; Miyamoto, H; Moldón, J; Moles, M; Moralejo, A; Nieto, D; Nilsson, K; Ninkovic, J; Orito, R; Oya, I; Paiano, S; Paoletti, R; Paredes, J M; Partini, S; Pasanen, M; Pascoli, D; Pauss, F; Pegna, R G; Perez-Torres, M A; Persic, M; Peruzzo, L; Prada, F; Prandini, E; Puchades, N; Puljak, I; Reichardt, I; Rhode, W; Ribó, M; Rico, J; Rissi, M; Rügamer, S; Saggion, A; Saito, T Y; Salvati, M; Sánchez-Conde, M; Satalecka, K; Scalzotto, V; Scapin, V; Schultz, C; Schweizer, T; Shayduk, M; Shore, S N; Sierpowska-Bartosik, A; Sillanpää, A; Sitarek, J; Sobczynska, D; Spanier, F; Spiro, S; Stamerra, A; Steinke, B; Struebig, J C; Suric, T; Takalo, L; Tavecchio, F; Temnikov, P; Terzic, T; Tescaro, D; Teshima, M; Torres, D F; Vankov, H; Wagner, R M; Weitzel, Q; Zabalza, V; Zandanel, F; Zanin, R; Neronov, A; Semikoz, D V

    2010-01-01

    Context: Part of the very high energy $\\gamma$-ray radiation coming from extragalactic sources is absorbed through the pair production process on the extragalactic background light photons. Extragalactic magnetic fields alter the trajectories of these cascade pairs and, in turn, convert cosmic background photons to gamma-ray energies by inverse Compton scattering. These secondary photons can form an extended halo around bright VHE sources. Aims: We searched for an extended emission around the bright blazars Mrk 421 and Mrk 501 using the MAGIC telescope data. Methods: If extended emission is present, the angular distribution of reconstructed gamma-ray arrival directions around the source is broader than for a point-like source. In the analysis of a few tens of hours of observational data taken from Mrk 421 and Mrk 501 we used a newly developed method that provides better angular resolution. This method is based on the usage of multidimensional decision trees. Comparing the measured shapes of angular distributi...

  18. Disordering and dissolution of [gamma][prime] precipitates under ion irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Bourdeau, F.; Camus, E.; Abromeit, C.; Wollenberger, H. (Hahn-Meitner-Institut Berlin GmbH, Glienicker Stragese 100, D-14109 Berlin (Germany))

    1994-12-01

    The stability of the [gamma][prime] phase of the nickel-base alloy Nimonic PE16 under irradiation with Ni[sup +] ions of 300-keV energy is studied by means of transmission electron microscopy. The disordering of the [gamma][prime] phase could be followed as a function of fluence. The main finding is the observation of weak but measurable superlattice reflections between 0.1 and 1 dpa after irradiation at room temperature. The superlattice reflections disappear in two steps. Their intensities decrease considerably within a fluence of 0.1 dpa, while weak intensities are observed up to a fluence of 1 dpa. These reflections disappear completely after a fluence of 2 dpa. The results are discussed within a model which considers both disordering and dissolution of precipitates under cascade producing irradiation.

  19. DNA binding properties of the small cascade subunit Csa5.

    Directory of Open Access Journals (Sweden)

    Michael Daume

    Full Text Available CRISPR-Cas systems provide immunity against viral attacks in archaeal and bacterial cells. Type I systems employ a Cas protein complex termed Cascade, which utilizes small CRISPR RNAs to detect and degrade the exogenic DNA. A small sequence motif, the PAM, marks the foreign substrates. Previously, a recombinant type I-A Cascade complex from the archaeon Thermoproteus tenax was shown to target and degrade DNA in vitro, dependent on a native PAM sequence. Here, we present the biochemical analysis of the small subunit, Csa5, of this Cascade complex. T. tenax Csa5 preferentially bound ssDNA and mutants that showed decreased ssDNA-binding and reduced Cascade-mediated DNA cleavage were identified. Csa5 oligomerization prevented DNA binding. Specific recognition of the PAM sequence was not observed. Phylogenetic analyses identified Csa5 as a universal member of type I-A systems and revealed three distinct groups. A potential role of Csa5 in R-loop stabilization is discussed.

  20. Chaotic Cascades for D-branes on Singularities

    CERN Document Server

    Franco, S; Herzog, C; Walcher, J; Franco, Sebastian; He, Yang-Hui; Herzog, Christopher; Walcher, Johannes

    2004-01-01

    We briefly review our work on the cascading renormalization group flows for gauge theories on D-branes probing Calabi-Yau singularities. Such RG flows are sometimes chaotic and exhibit duality walls. We construct supergravity solutions dual to logarithmic flows for these theories. We make new observations about a surface of conformal theories and more complicated supergravity solutions.

  1. Network protection against worms and cascading failures using modularity partitioning

    NARCIS (Netherlands)

    Omic, J.; Hernandez, J.M.; Van Mieghem, P.

    2010-01-01

    Communication networks are prone to virus and worms spreading and cascading failures. Recently, a number of social networking worms have spread over public Web sites. Another example is error propagation in routing tables, such as in BGP tables. The immunization and error curing applied to these sce

  2. Laser-Pulse-Shape Control of Seeded QED Cascades

    CERN Document Server

    Tamburini, Matteo; Keitel, Christoph H

    2015-01-01

    The emergence of electron-positron cascades via ultrastrong electromagnetic fields constitutes a prominent manifestation of the complex interplay between strong-field QED processes and multiparticle dynamics. Here the onset and development of electron-positron cascades are investigated in the head-on collision of two realistic tightly focused ultraintense optical laser pulses in a tenuous gas. As a consequence of the large ponderomotive forces expelling all electrons of the gas from the focal volume, we demonstrate that the onset of QED cascades may be prevented even at intensities around $10^{26}\\;\\text{W/cm$^2$}$ by focusing the laser energy almost down to the diffraction limit. Alternatively, a well controlled development of a QED cascade may be facilitated at laser intensities below $10^{24}\\;\\text{W/cm$^2$}$ per beam by enlarged focal areas and a rapid rise of the pulse or at total powers near $20\\;\\text{PW}$ by employing suitable high-$Z$ gases.

  3. Cascading Constrained 2-D Arrays using Periodic Merging Arrays

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Laursen, Torben Vaarby

    2003-01-01

    We consider a method for designing 2-D constrained codes by cascading finite width arrays using predefined finite width periodic merging arrays. This provides a constructive lower bound on the capacity of the 2-D constrained code. Examples include symmetric RLL and density constrained codes....... Numerical results for the capacities are presented....

  4. Thresholds and Complex Dynamics of Interdependent Cascading Infrastructure Systems

    Science.gov (United States)

    Carreras, B. A.; Newman, D. E.; Dobson, I.; Lynch, V. E.; Gradney, Paul

    Critical infrastructures have a number of the characteristic properties of complex systems. Among these are infrequent large failures through cascading events. These events, though infrequent, often obey a power law distribution in their probability versus size which suggests that conventional risk analysis does not apply to these systems. Real infrastructure systems typically have an additional layer of complexity, namely the heterogeneous coupling to other infrastructure systems that can allow a failure in one system to propagate to the other system. Here, we model the infrastructure systems through a network with complex system dynamics. We use both mean field theory to get analytic results and a numerical complex systems model, Demon, for computational results. An isolated system has bifurcated fixed points and a cascading threshold which is the same as the bifurcation point. When systems are coupled, this is no longer true and the cascading threshold is different from the bifurcation point of the fixed point solutions. This change in the cascading threshold caused by the interdependence of the system can have an impact on the "safe operation" of interdependent infrastructure systems by changing the critical point and even the power law exponent.

  5. Cascading A*: a Parallel Approach to Approximate Heuristic Search

    OpenAIRE

    Gu, Yan

    2014-01-01

    In this paper, we proposed a new approximate heuristic search algorithm: Cascading A*, which is a two-phrase algorithm combining A* and IDA* by a new concept "envelope ball". The new algorithm CA* is efficient, able to generate approximate solution and any-time solution, and parallel friendly.

  6. A psychological cascade model for persisting voice problems in teachers

    NARCIS (Netherlands)

    de Jong, FICRS; Cornelis, BE; Wuyts, FL; Kooijman, PGC; Schutte, HK; Oudes, MJ; Graamans, K

    2003-01-01

    In 76 teachers with persisting voice problems, the maintaining factors and coping strategies were examined. Physical, functional, psychological and socioeconomic factors were assessed. A parallel was drawn to a psychological cascade model designed for patients with chronic back pain. The majority of

  7. On the cascade approach to the quantum multiscattering problem

    Energy Technology Data Exchange (ETDEWEB)

    Salcedo, L.L. [Departamento de Fisica Moderna, Universidad de Granada, E-18071 Granada (Spain)

    2003-01-01

    The multiscattering problem is studied in the matrix density formalism. We study how to isolate the quasi-classical degrees of freedom in order to connect them with a cascade approach. The different problems that arise, as well as their possible solutions, are discussed and exemplified with a pion-nucleus model. (orig.)

  8. CASCADIC MULTIGRID FOR FINITE VOLUME METHODS FOR ELLIPTIC PROBLEMS

    Institute of Scientific and Technical Information of China (English)

    Zhong-ci Shi; Xue-jun Xu; Hong-ying Man

    2004-01-01

    In this paper, some effective cascadic multigrid methods are proposed for solving the large scale symmetric or nonsymmetric algebraic systems arising from the finite volumemethods for second order elliptic problems. Its is shown that these algorithms are optimal in both accuracy and computational complexity. Numerical expermients are repored to support out theory.

  9. Calculating Node Importance Considering Cascading Failure in Traffic Networks

    Directory of Open Access Journals (Sweden)

    Zhengwu Wang

    2013-01-01

    Full Text Available The traffic network is a scale-free network. In selective attack, invalidation of few key nodes may lead to network failure so it is important to find these key nodes. In this study, the key nodes are determined by establishing calculating methods of node importance based on cascading failure behaviors. First, a cascading failure model of traffic network is posed. Its differences from current models are as follows: 1 The upper travel network and lower road network are influenced each other, 2 Capacity of nodes and links are given at first but not in direct proportion to initial flow that is related to initial capacity, 3 Travel time is used to describe status of links, 4 Capacity of links may change. The evaluation method of node importance of traffic network considering cascading failure is proposed then based on node deletion. It uses congestion status of cascading failure network to describe the node importance and algorithm procedures are designed to estimate importance of all nodes. At the end, the experiment analysis shows that network structure and traveler behaviors have in significant influence on node importance.

  10. Optical Pulse Generation with Self-Cascaded Electroabsorption Modulator

    Institute of Scientific and Technical Information of China (English)

    WU Jian; QiU Ji-Fang; ZHOU Guang-Tao; XU Kun; LIN Jin-Tong

    2007-01-01

    A novel scheme for pulse generation with a self-cascaded electroabsorption modulator is presented and experi mentally demonstrated at 10 GHz.In the case of optimal tuning of time delay in the fibre loop,the improvement of 50% on pulsewidth with improved extinction ratio is obtained and the narrowest pulse generated with this method is about 11 ps.

  11. Cascades on a stochastic pulse-coupled network.

    Science.gov (United States)

    Wray, C M; Bishop, S R

    2014-09-12

    While much recent research has focused on understanding isolated cascades of networks, less attention has been given to dynamical processes on networks exhibiting repeated cascades of opposing influence. An example of this is the dynamic behaviour of financial markets where cascades of buying and selling can occur, even over short timescales. To model these phenomena, a stochastic pulse-coupled oscillator network with upper and lower thresholds is described and analysed. Numerical confirmation of asynchronous and synchronous regimes of the system is presented, along with analytical identification of the fixed point state vector of the asynchronous mean field system. A lower bound for the finite system mean field critical value of network coupling probability is found that separates the asynchronous and synchronous regimes. For the low-dimensional mean field system, a closed-form equation is found for cascade size, in terms of the network coupling probability. Finally, a description of how this model can be applied to interacting agents in a financial market is provided.

  12. Detecting Early Signatures of Persuasion in Information Cascades

    Science.gov (United States)

    2014-01-01

    ADDRESS. Indiana University at Bloomington Trustees of Indiana University 509 E 3RD ST Bloomington, IN 47401 -3654 Detecting Early Signatures of Persuasion ...SMISC  Project:   DESPIC:  Detecting  Early  Signatures  of   Persuasion  in  Information  Cascades     Teams:   Indiana

  13. Common features at the start of the neurodegeneration cascade

    OpenAIRE

    Rubén Hervás; Javier Oroz; Albert Galera-Prat; Oscar Goñi; Alejandro Valbuena; Andrés M Vera; Angel Gómez-Sicilia; Fernando Losada-Urzáiz; Uversky, Vladimir N.; Margarita Menéndez; Laurents, Douglas V.; Marta Bruix; Mariano Carrión-Vázquez

    2012-01-01

    Amyloidogenic neurodegenerative diseases are incurable conditions with high social impact that are typically caused by specific, largely disordered proteins. However, the underlying molecular mechanism remains elusive to established techniques. A favored hypothesis postulates that a critical conformational change in the monomer (an ideal therapeutic target) in these >neurotoxic proteins> triggers the pathogenic cascade. We use force spectroscopy and a novel methodology for unequivocal single-...

  14. Low crosstalk Arrayed Waveguide Grating with Cascaded Waveguide Grating Filter

    Energy Technology Data Exchange (ETDEWEB)

    Deng Yang; Liu Yuan; Gao Dingshan, E-mail: dsgao@mail.hust.edu.cn [Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074 (China)

    2011-02-01

    We propose a highly compact and low crosstalk arrayed waveguide grating (AWG) with cascaded waveguide grating (CWGF). The side lobes of the silicon nanowire AWG, which are normally introduced by fabrication errors, can be effectively suppressed by the CWGF. And the crosstalk can be improved about 15dB.

  15. Successful Treatment Of Homozygous Familial Hypercholesterolemia Using Cascade Filtration Plasmapheresis

    Directory of Open Access Journals (Sweden)

    Fatih Kardas

    2012-12-01

    Full Text Available OBJECTIVE: The aim of our study is to discuss the efficacy of low-density lipoprotein-cholesterol (LDL-C apheresis procedure using the cascade filtration system for pediatric patients with homozygous familial hypercholesterolemia (FH, and to clarify the adverse effects and difficulties. METHODS: LDL apheresis using the cascade filtration system was performed in 3 pediatric patients with homozygous FH. In total, 120 apheresis sessions were performed for all patients. RESULTS: Cascade filtration therapy significantly reduced the mean LDL-C values from 418 ± 62 mg/dl to 145 ± 43 mg/dl (p<0.05. We determined an acute mean reduction in the plasma levels of total cholesterol (57.9%, LDL cholesterol (70.8%, and high-density lipoprotein (HDL cholesterol (40.7%. Treatments were well tolerated. The most frequent clinical adverse effects were hypotension in 3 sessions (2.5%, chills/feeling cold (1.7% in 2 sessions, and nausea and vomiting in 3 sessions (2.5%. CONCLUSION: Our experience with three patients using the cascade filtration system were, good clinical outcomes, laboratory findings, safety of usage, minor adverse effects and technical problems.

  16. Optimization Control of Bidirectional Cascaded DC-AC Converter Systems

    DEFF Research Database (Denmark)

    Tian, Yanjun

    in different power flow directions, a bidirectional impedance control method is also proposed to unify and improve the system stability. Control system type number is also analyzed in this thesis, then a symmetric proportional control method for the two stage cascaded converter is proposed to reduce the dc...

  17. Impedance Interaction Modeling and Analysis for Bidirectional Cascaded Converters

    DEFF Research Database (Denmark)

    Tian, Yanjun; Deng, Fujin; Chen, Zhe;

    2015-01-01

    more uncertainty to the system stability. An investigation is performed here for showing that the forward and reverse interactions are prominently different in terms of dynamics and stability even though the cascaded converter control remains unchanged. An important guideline has been drawn...

  18. Dispersive waves in fs cascaded second-harmonic generation

    DEFF Research Database (Denmark)

    Bache, Morten; Bang, Ole; Krolikowski, Wieslaw;

    2009-01-01

    Dispersive waves are observed in simulations of cascaded (phase-mismatched) second-harmonic generation. When generating ultra-short fs compressed near-IR solitons the dispersive waves are strongly red-shifted, depending on the soliton wavelength. Semi-analytical calculations predict the wavelengths....

  19. Multicomponent gas analysis using broadband quantum cascade laser spectroscopy

    NARCIS (Netherlands)

    Reyes Reyes, A.; Hou, Z.; Van Mastrigt, E.; Horsten, R.C.; De Jongste, J.C.; Pijnenburg, M.W.; Urbach, H.P.; Bhattacharya, N.

    2014-01-01

    We present a broadband quantum cascade laser-based spectroscopic system covering the region between 850 and 1250 cm−1. Its robust multipass cavity ensures a constant interaction length over the entire spectral region. The device enables the detection and identification of numerous molecules present

  20. An Algebraic Approach to Signaling Cascades with n Layers

    DEFF Research Database (Denmark)

    Feliu, Elisenda; Knudsen, Michael; Andersen, Lars Nørvang;

    2011-01-01

    Posttranslational modification of proteins is key in transmission of signals in cells. Many signaling pathways contain several layers of modification cycles that mediate and change the signal through the pathway. Here, we study a simple signaling cascade consisting of n layers of modification...

  1. Vortex merging and spectral cascade in two-dimensional flows

    DEFF Research Database (Denmark)

    Nielsen, A.H.; He, X.; Juul Rasmussen, J.;

    1996-01-01

    The merging of two identical vortices is studied numerically using a spectral code. It is noted that the enstrophy cascade is most active on the distorted vortex boundaries, with a Kolmogorov-like spectrum E(k) approximate to k(-alpha), alpha less than or equal to 4, developed at high wave numbers...

  2. Turbulence characteristics in a supersonic cascade wake flow

    Energy Technology Data Exchange (ETDEWEB)

    Andrew, P.L.; Ng, W.F. (Virginia Polytechnic Inst. and State Univ., Blacksburg, VA (United States))

    1994-10-01

    The turbulent character of the supersonic wake of a linear cascade of fan airfoils has been studied using a two-component laser-doppler anemometer. The cascade was tested in the Virginia Polytechnic Institute and State University intermittent wind tunnel facility, where the Mach and Reynolds numbers were 2.36 and 4.8 [times] 10[sup 6], respectively. In addition to mean flow measurements, Reynolds normal and shear stresses were measured as functions of cascade incidence angle and streamwise locations spanning the near-wake and the far-wake. The extremities of profiles of both the mean and turbulent wake properties were found to be strongly influenced by upstream shock-boundary-layer interactions, the strength of which varied with cascade incidence. In contrast, the peak levels of turbulence properties within the shear layer were found to be largely independent of incidence, and could be characterized in terms of the streamwise position only. The velocity defect turbulence level was found to be 23%, and the generally accepted value of the turbulence structural coefficient of 0.30 was found to be valid for this flow. The degree of similarity of the mean flow wake profiles was established, and those profiles demonstrating the most similarity were found to approach a state of equilibrium between the mean and turbulent properties. In general, this wake flow may be described as a classical free shear flow, upon which the influence of upstream shock-boundary-layer interactions has been superimposed.

  3. Efficient Design of Multi-stage Cascade Waveband Separator

    Institute of Scientific and Technical Information of China (English)

    Samrat Ganguly; Rauf Izmailov; Nan Tu; Ting Wang

    2003-01-01

    We propose a cascade system of filters for realizing a non-uniform waveband separation for optical networks. The use of such separation is required at the DEMUX stage in a optical OXC switching wavebands. The design of the system is based on optimized balanced tree, which minimizes the overall optical loss.

  4. Emergence of a turbulent cascade in a quantum gas

    Science.gov (United States)

    Navon, Nir; Gaunt, Alexander L.; Smith, Robert P.; Hadzibabic, Zoran

    2016-11-01

    A central concept in the modern understanding of turbulence is the existence of cascades of excitations from large to small length scales, or vice versa. This concept was introduced in 1941 by Kolmogorov and Obukhov, and such cascades have since been observed in various systems, including interplanetary plasmas, supernovae, ocean waves and financial markets. Despite much progress, a quantitative understanding of turbulence remains a challenge, owing to the interplay between many length scales that makes theoretical simulations of realistic experimental conditions difficult. Here we observe the emergence of a turbulent cascade in a weakly interacting homogeneous Bose gas—a quantum fluid that can be theoretically described on all relevant length scales. We prepare a Bose-Einstein condensate in an optical box, drive it out of equilibrium with an oscillating force that pumps energy into the system at the largest length scale, study its nonlinear response to the periodic drive, and observe a gradual development of a cascade characterized by an isotropic power-law distribution in momentum space. We numerically model our experiments using the Gross-Pitaevskii equation and find excellent agreement with the measurements. Our experiments establish the uniform Bose gas as a promising new medium for investigating many aspects of turbulence, including the interplay between vortex and wave turbulence, and the relative importance of quantum and classical effects.

  5. Experimental investigation on a high subsonic compressor cascade flow

    Directory of Open Access Journals (Sweden)

    Zhang Haideng

    2015-08-01

    Full Text Available With the aim of deepening the understanding of high-speed compressor cascade flow, this paper reports an experimental study on NACA-65 K48 compressor cascade with high subsonic inlet flow. With the increase of passage pressurizing ability, endwall boundary layer behavior is deteriorated, and the transition zone is extended from suction surface to the endwall as the adverse pressure gradient increases. Cross flow from endwall to midspan, mixing of corner boundary layer and the main stream, and reversal flow on the suction surface are caused by corner separation vortex structures. Passage vortex is the main corner separation vortex. During its movement downstream, the size grows bigger while the rotating direction changes, forming a limiting circle. With higher incidence, corner separation is further deteriorated, leading to higher flow loss. Meanwhile, corner separation structure, flow mixing characteristics and flow loss distribution vary a lot with the change of incidence. Compared with low aspect-ratio model, corner separation of high aspect-ratio model moves away from the endwall and is more sufficiently developed downstream the cascade. Results obtained present details of high-speed compressor cascade flow, which is rare in the relating research fields and is beneficial to mechanism analysis, aerodynamic optimization and flow control design.

  6. IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.

    Science.gov (United States)

    Chakrabarty, Paramita; Ceballos-Diaz, Carolina; Beccard, Amanda; Janus, Christopher; Dickson, Dennis; Golde, Todd E; Das, Pritam

    2010-05-01

    Reactive gliosis surrounding amyloid beta (Abeta) plaques is an early feature of Alzheimer's disease pathogenesis and has been postulated to represent activation of the innate immune system in an apparently ineffective attempt to clear or neutralize Abeta aggregates. To evaluate the role of IFN-gamma-mediated neuroinflammation on the evolution of Abeta pathology in transgenic (Tg) mice, we have expressed murine IFN-gamma (mIFN-gamma) in the brains of Abeta precursor protein (APP) Tg mice using recombinant adeno-associated virus serotype 1. Expression of mIFN-gamma in brains of APP TgCRND8 mice results in robust noncell autonomous activation of microglia and astrocytes, and a concomitant significant suppression of Abeta deposition. In these mice, mIFN-gamma expression upregulated multiple glial activation markers, early components of the complement cascade as well as led to infiltration of Ly-6c positive peripheral monocytes but no significant effects on APP levels, APP processing or steady-state Abeta levels were noticed in vivo. Taken together, these results suggest that mIFN-gamma expression in the brain suppresses Abeta accumulation through synergistic effects of activated glia and components of the innate immune system that enhance Abeta aggregate phagocytosis.

  7. Discovery of extended VHE \\gamma-ray emission from the vicinity of the young massive stellar cluster Westerlund 1

    CERN Document Server

    Abramowski, A; Aharonian, F; Akhperjanian, A G; Anton, G; Balzer, A; Barnacka, A; de Almeida, U Barres; Becherini, Y; Becker, J; Behera, B; Bernlöhr, K; Birsin, E; Biteau, J; Bochow, A; Boisson, C; Bolmont, J; Bordas, P; Brucker, J; Brun, F; Brun, P; Bulik, T; Büsching, I; Carrigan, S; Casanova, S; Cerruti, M; Chadwick, P M; Charbonnier, A; Chaves, R C G; Cheesebrough, A; Chounet, L -M; Clapson, A C; Coignet, G; Cologna, G; Conrad, J; Dalton, M; Daniel, M K; Davids, I D; Degrange, B; Deil, C; Dickinson, H J; Djannati-Ataï, A; Domainko, W; Drury, L O'C; Dubois, F; Dubus, G; Dutson, K; Dyks, J; Dyrda, M; Egberts, K; Eger, P; Espigat, P; Fallon, L; Farnier, C; Fegan, S; Feinstein, F; Fernandes, M V; Fiasson, A; Fontaine, G; Förster, A; Füßling, M; Gallant, Y A; Gast, H; Gérard, L; Gerbig, D; Giebels, B; Glicenstein, J F; Glück, B; Goret, P; Göring, D; Häffner, S; Hague, J D; Hampf, D; Hauser, M; Heinz, S; Heinzelmann, G; Henri, G; Hermann, G; Hinton, J A; Hoffmann, A; Hofmann, W; Hofverberg, P; Holler, M; Horns, D; Jacholkowska, A; de Jager, O C; Jahn, C; Jamrozy, M; Jung, I; Kastendieck, M A; Katarzynski, K; Katz, U; Kaufmann, S; Keogh, D; Khangulyan, D; Khélifi, B; Klochkov, D; Kluźniak, W; Kneiske, T; Komin, Nu; Kosack, K; Kossakowski, R; Laffon, H; Lamanna, G; Lennarz, D; Lohse, T; Lopatin, A; Lu, C -C; Marandon, V; Marcowith, A; Masbou, J; Maurin, D; Maxted, N; Mayer, M; McComb, T J L; Medina, M C; Méhault, J; Moderski, R; Moulin, E; Naumann, C L; Naumann-Godo, M; de Naurois, M; Nedbal, D; Nekrassov, D; Nguyen, N; Nicholas, B; Niemiec, J; Nolan, S J; Ohm, S; Wilhelmi, E de Ona; Opitz, B; Ostrowski, M; Oya, I; Panter, M; Arribas, M Paz; Pedaletti, G; Pelletier, G; Petrucci, P -O; Pita, S; Pühlhofer, G; Punch, M; Quirrenbach, A; Raue, M; Rayner, S M; Reimer, A; Reimer, O; Renaud, M; Reyes, R de los; Rieger, F; Ripken, J; Rob, L; Rosier-Lees, S; Rowell, G; Rudak, B; Rulten, C B; Ruppel, J; Sahakian, V; Sanchez, D; Santangelo, A; Schlickeiser, R; Schöck, F M; Schulz, A; Schwanke, U; Schwarzburg, S; Schwemmer, S; Sheidaei, F; Sikora, M; Skilton, J L; Sol, H; Spengler, G; Stawarz, L; Steenkamp, R; Stegmann, C; Stinzing, F; Stycz, K; Sushch, I; Szostek, A; Tavernet, J -P; Terrier, R; Tluczykont, M; Valerius, K; van Eldik, C; Vasileiadis, G; Venter, C; Vialle, J P; Viana, A; Vincent, P; Völk, H J; Volpe, F; Vorobiov, S; Vorster, M; Wagner, S J; Ward, M; White, R; Wierzcholska, A; Zacharias, M; Zajczyk, A; Zdziarski, A A; Zech, A; Zechlin, H -S

    2011-01-01

    Results obtained in very-high-energy (VHE; E > 100 GeV) \\gamma-ray observations performed with the H.E.S.S. telescope array are used to investigate particle acceleration processes in the vicinity of the young massive stellar cluster Westerlund 1 (Wd 1). Imaging of Cherenkov light from \\gamma-ray induced particle cascades in the Earth's atmosphere is used to search for VHE \\gamma\\ rays from the region around Wd 1. Possible catalogued counterparts are searched for and discussed in terms of morphology and energetics of the H.E.S.S. source. The detection of the degree-scale extended VHE \\gamma-ray source HESS J1646-458 is reported based on 45 hours of H.E.S.S. observations performed between 2004 and 2008. The VHE \\gamma-ray source is centred on the nominal position of Wd 1 and detected with a total statistical significance of ~20\\sigma. The emission region clearly extends beyond the H.E.S.S. point-spread function (PSF). The differential energy spectrum follows a power law in energy with an index of \\Gamma=2.19 \\p...

  8. CASCADIC MULTIGRID METHOD FOR THE MORTAR ELEMENT METHOD FOR P1 NONCONFORMING ELEMENT

    Institute of Scientific and Technical Information of China (English)

    Chun-jia Bi; Dan-hui Hong

    2005-01-01

    In this paper, we consider the cascadic multigrid method for the mortar P1 nonconforming element which is used to solve the Poisson equation and prove that the cascadic conjugate gradient method is accurate with optimal complexity.

  9. Search for the Radiative Penguin Decays B+ -> rho+ gamma, B0 -> rho0 gamma, and B0 -> omega gamma

    CERN Document Server

    Aubert, B; Boutigny, D; Couderc, F; Gaillard, J M; Hicheur, A; Karyotakis, Yu; Lees, J P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Ronan, Michael T; Shelkov, V G; Wenzel, W A; Barrett, M; Ford, K E; Harrison, T J; Hart, A J; Hawkes, C M; Morgan, S E; Watson, A T; Fritsch, M; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Wilson, F F; Çuhadar-Dönszelmann, T; Hearty, C; Knecht, N S; Mattison, T S; McKenna, J A; Thiessen, D; Khan, A; Kyberd, P; Teodorescu, L; Blinov, A E; Blinov, V E; Druzhinin, V P; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Eschrich, I; Kirkby, D; Lankford, A J; Mandelkern, M A; Mommsen, R K; Röthel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Foulkes, S D; Gary, J W; Shen, B C; Wang, K; Del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, S; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Eisner, A M; Heusch, C A; Kroseberg, J; Lockman, W S; Nesom, G; Schalk, T; Schumm, B A; Seiden, A; Spradlin, P; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S M; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Smith, J G; Zhang, J; Zhang, L; Chen, A; Harton, J L; Soffer, A; Toki, W H; Wilson, R J; Zeng, Q L; Altenburg, D; Brandt, T; Brose, J; Dickopp, M; Feltresi, E; Hauke, A; Lacker, H M; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Petzold, A; Schubert, J; Schubert, Klaus R; Schwierz, R; Spaan, B; Sundermann, J E; Bernard, D; Bonneaud, G R; Brochard, F; Grenier, P; Schrenk, S; Thiebaux, C; Vasileiadis, G; Verderi, M; Bard, D J; Clark, P J; Lavin, D; Muheim, F; Playfer, S; Xie, Y; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; De Sangro, R; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Brandenburg, G; Chaisanguanthum, K S; Morii, M; Won, E; Dubitzky, R S; Langenegger, U; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Gaillard, J R; Morton, G W; Nash, J A; Nikolich, M B; Taylor, G P; Charles, M J; Grenier, G J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Yi, J; Biasini, M; Covarelli, R; Pioppi, M; Davier, M; Giroux, X; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F R; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Chavez, C A; Coleman, J P; Forster, I J; Fry, J R; Gabathuler, Erwin; Gamet, R; Hutchcroft, D E; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Mohanty, G B; Cowan, G; Flack, R L; Flächer, H U; Green, M G; Jackson, P S; McMahon, T R; Ricciardi, S; Salvatore, F; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Lafferty, G D; Lyon, A J; Williams, J C; Farbin, A; Hulsbergen, W D; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Stängle, H; Willocq, S; Cowan, R; Sciolla, G; Sekula, S J; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, F; Bauer, J M; Cremaldi, L M; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Zhao, H W; Brunet, S; Côté, D; Taras, P; Nicholson, H; Cavallo, N; Lista, L; Monorchio, D; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M; Bulten, H; Raven, G; Snoek, H L; Wilden, L; Jessop, C P; LoSecco, J M; Allmendinger, T; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Rahimi, A M; Ter-Antonian, R; Wong, Q K; Brau, J E; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; La Vaissière, C de; Del Buono, L; Hamon, O; John, M J J; Leruste, P; Malcles, J; Ocariz, J; Pivk, M; Roos, L; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martínez-Vidal, F; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lau, Y P; Lü, C; Miftakov, V; Olsen, J; Smith, A J S; Telnov, A V; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Li Gioi, L; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai-Tehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B J; Geddes, N I; Gopal, G P; Olaiya, E O; Aleksan, Roy; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P F; Hamel de Monchenault, G; Kozanecki, Witold; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yéche, C; Zito, M; Purohit, M V; Weidemann, A W; Wilson, J R; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmüller, O L; Claus, R; Convery, M R; Cristinziani, M; De Nardo, Gallieno; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W M; Elsen, E E; Fan, S; Field, R C; Glanzman, T; Gowdy, S J; Hadig, T; Halyo, V; Hast, C; Hrynóva, T; Innes, W R; Kelsey, M H; Kim, P; Kocian, M L; Leith, D W G S; Libby, J; Luitz, S; Lüth, V; Lynch, H L; Marsiske, H; Messner, R; Müller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Vavra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wittgen, M; Wright, D H; Yarritu, A K; Young, C C; Burchat, Patricia R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Satpathy, A; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bóna, M; Gallo, F; Gamba, D; Bosisio, L; Cartaro, C; Cossutti, F; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R V; Roney, J M; Sobie, R J; Band, H R; Cheng, B; Dasu, S; Datta, M; Eichenbaum, A M; Graham, M; Hollar, J J; Johnson, J R; Kutter, P E; Li, H; Liu, R; Mihályi, A; Mohapatra, A K; Pan, Y; Prepost, R; Tan, P; Von Wimmersperg-Töller, J H; Wu, J; Wu, S L; Yu, Z; Greene, M G; Neal, H

    2004-01-01

    A search for the decays B --> rho(770) gamma and B0 --> omega(782)gamma is performed on a sample of 211 million Y(4S)->BBbar events collected by the BABAR detector at the PEP-II asymmetric-energy e+e- storage ring. No evidence for the decays is seen. We set the following limits on the individual branching fractions BF(B --> rho+ gamma) rho0 gamma) omega gamma) (rho/omega) gamma]<1.2 x 10^-6 and constrain V_td/V_ts< 0.19 at the 90% C.L.

  10. Observation of B_s to phi gamma and Search for B_s to gamma gamma Decays at Belle

    CERN Document Server

    Wicht, J; Aihara, H; Arinstein, K; Aulchenko, V; Aushev, T; Bakich, A M; Balagura, V; Bay, A; Belous, K S; Bhardwaj, V; Bitenc, U; Bondar, A; Bozek, A; Brako, M; Browder, T E; Chang, cP; Chao, Y; Chen, A; Chen, K F; Chen, W T; Cheon, B G; Chistov, R; Cho, I S; Choi, Y; Dalseno, J; Dash, M; Drutskoy, A; Eidelman, S; Gabyshev, N; Goldenzweig, P; Golob, B; Haba, J; Hayasaka, K; Hazumi, M; Heffernan, D; Hoshi, Y; Hou, W S; Hsiung, Y B; Hyun, H J; Iijima, T; Inami, K; Ishikawa, A; Ishino, H; Itoh, R; Iwasaki, Y; Kah, D H; Kaji, H; Kang, J H; Kapusta, P; Kawai, H; Kawasaki, T; Kichimi, H; Kim, H J; Kim, H O; Kim, S K; Kim, Y J; Kinoshita, K; Korpar, S; Krian, P; Kumar, R; Kuo, C C; Kwon, Y J; Lange, J S; Lee, J; Lee, z J S; Lee, S E; Lesiak, T; Limosani, A; Lin, S W; Liu, Y; Liventsev, D; Mandl, F; McOnie, S; Medvedeva, T; Mitaroff, W A; Miyabayashi, K; Miyake, H; Miyata, H; Miyazaki, Y; Mizuk, R; Mohapatra, D; Moloney, G R; Nakao, M; Natkaniec, Z; Nishida, S; Nitoh, O; Nozaki, T; Ogawa, S; Ohshima, T; Okuno, S; Ozaki, H; Pakhlov, P; Pakhlova, G; Palka, H; Park, C W; Park, H; Park, K S; Pestotnik, R; Piilonen, L E; Sakai, Y; Schneider, O; Schümann, J; Schwartz, A J; Senyo, K; Sevior, M E; Shapkin, M; Shibuya, H; Shiu, J G; Shwartz, B; Singh, J B; Somov, A; Stani, S; Stari, M; Sumisawa, K; Sumiyoshi, T; Takasaki, F; Tamai, K; Tanaka, M; Taylor, G N; Teramoto, Y; Trabelsi, cK; Tsuboyama, T; Uehara, S; Ueno, K; Unno, Y; Uno, S; Ushiroda, Y; Usov, Yu; Varner, G; Vervink, K; Villa, S; Wang, C H; Wang, P; Wang, X L; Watanabe, Y; Won, E; Yabsley, B D; Yamashita, Y; Yamauchi, M; Yusa, Y; Zhang, Z P; Zhilich, V; Zupanc, A; Zwahlen, N

    2007-01-01

    We search for the radiative penguin decays B_s to phi gamma and B_s to gamma gamma in a 23.6 fb-1 data sample collected at the Upsilon(5S) resonance with the Belle detector at the KEKB e+e- asymmetric-energy collider. We observe for the first time a radiative penguin decay of the B_s meson in the B_s to phi gamma mode. No significant B_s to gamma gamma signal is observed.

  11. Hydrothermal heat discharge in the Cascade Range, northwestern United States

    Science.gov (United States)

    Ingebritsen, S.E.; Mariner, R.H.

    2010-01-01

    Hydrothermal heat discharge in the Cascade Range includes the heat discharged by thermal springs, by "slightly thermal" springs that are only a few degrees warmer than ambient temperature, and by fumaroles. Thermal-spring heat discharge is calculated on the basis of chloride-flux measurements and geothermometer temperatures and totals ~ 240 MW in the U.S. part of the Cascade Range, excluding the transient post-1980 discharge at Mount St. Helens (~80 MW as of 2004-5). Heat discharge from "slightly thermal" springs is based on the degree of geothermal warming (after correction for gravitational potential energy effects) and totals ~. 660. MW. Fumarolic heat discharge is calculated by a variety of indirect and direct methods and totals ~160 MW, excluding the transient mid-1970s discharge at Mount Baker (~80 MW) and transient post-1980 discharge at Mount St. Helens (>. 230. MW as of 2005). Other than the pronounced transients at Mount St. Helens and Mount Baker, hydrothermal heat discharge in the Cascade Range appears to be fairly steady over a ~25-year period of measurement. Of the total of ~. 1050. MW of "steady" hydrothermal heat discharge identified in the U.S. part of the Cascade Range, less than 50. MW occurs north of latitude 45??15' N (~0.1 MW per km arc length from 45??15' to 49??N). Much greater rates of hydrothermal heat discharge south of 45??15'N (~1.7 MW per km arc length from 40?? to 45??15'N) may reflect the influence of Basin and Range-style extensional tectonics (faulting) that impinges on the Cascades as far north as Mount Jefferson but is not evident farther north. ?? 2010.

  12. Structure of the archaeal Cascade subunit Csa5

    Science.gov (United States)

    Reeks, Judith; Graham, Shirley; Anderson, Linzi; Liu, Huanting; White, Malcolm F.; Naismith, James H.

    2013-01-01

    The Cascade complex for CRISPR-mediated antiviral immunity uses CRISPR RNA (crRNA) to target invading DNA species from mobile elements such as viruses, leading to their destruction. The core of the Cascade effector complex consists of the Cas5 and Cas7 subunits, which are widely conserved in prokaryotes. Cas7 binds crRNA and forms the helical backbone of Cascade. Many archaea encode a version of the Cascade complex (denoted Type I-A) that includes a Csa5 (or small) subunit, which interacts weakly with the core proteins. Here, we report the crystal structure of the Csa5 protein from Sulfolobus solfataricus. Csa5 comprises a conserved α-helical domain with a small insertion consisting of a weakly conserved β-strand domain. In the crystal, the Csa5 monomers have multimerized into infinite helical threads. At each interface is a strictly conserved intersubunit salt bridge, deletion of which disrupts multimerization. Structural analysis indicates a shared evolutionary history among the small subunits of the CRISPR effector complexes. The same α-helical domain is found in the C-terminal domain of Cse2 (from Type I-E Cascade), while the N-terminal domain of Cse2 is found in Cmr5 of the CMR (Type III-B) effector complex. As Cmr5 shares no match with Csa5, two possibilities present themselves: selective domain loss from an ancestral Cse2 to create two new subfamilies or domain fusion of two separate families to create a new Cse2 family. A definitive answer awaits structural studies of further small subunits from other CRISPR effector complexes. PMID:23846216

  13. Nitric Oxide and Prostaglandins Potentiate the Liver Regeneration Cascade

    Directory of Open Access Journals (Sweden)

    Jodi M Schoen Smith

    2006-01-01

    Full Text Available The liver has the remarkable ability to regenerate following damage or surgical resection. Although this feature of the liver has been studied for over 100 years, the trigger of the liver regeneration cascade remains controversial. Recent experimental evidence supports the hypothesis that nitric oxide (NO and prostaglandins (PGs, released secondary to an increase in the blood flow-to-liver mass ratio following two-thirds partial hepatectomy (PHx, work synergistically to trigger liver regeneration. To extend this research, the hypothesis that NO and PGs are potential therapeutic targets to potentiate the liver regeneration cascade is tested. The NO donor s-nitroso-n-acetylpenicillamine, the phosphodiesterase V antagonist zaprinast (ZAP and PGI2 each potentiated c-fos messenger RNA expression, an index of initiation of the liver regeneration cascade, following PHx. Also, the triple combination of s-nitroso-n-acetylpenicillamine, ZAP and PGI2 potentiated c-fos messenger RNA expression. These results support the hypothesis that NO and PGs can potentiate initiation of the regeneration cascade. An additional index of liver weight restoration 48 h after PHx was also used to test the hypothesis, because this index encompasses the entire liver regeneration cascade. ZAP and 6-keto-PGF1α, a stable metabolite of PGI2, and the combination of ZAP and 6-keto-PGF1α, each potentiated liver weight restoration 48 h after PHx. These results also provide support for the hypothesis that NO and PGs are possible therapeutic targets to potentiate liver regeneration following surgical resection.

  14. A hidden feedback in signaling cascades is revealed.

    Directory of Open Access Journals (Sweden)

    Alejandra C Ventura

    2008-03-01

    Full Text Available Cycles involving covalent modification of proteins are key components of the intracellular signaling machinery. Each cycle is comprised of two interconvertable forms of a particular protein. A classic signaling pathway is structured by a chain or cascade of basic cycle units in such a way that the activated protein in one cycle promotes the activation of the next protein in the chain, and so on. Starting from a mechanistic kinetic description and using a careful perturbation analysis, we have derived, to our knowledge for the first time, a consistent approximation of the chain with one variable per cycle. The model we derive is distinct from the one that has been in use in the literature for several years, which is a phenomenological extension of the Goldbeter-Koshland biochemical switch. Even though much has been done regarding the mathematical modeling of these systems, our contribution fills a gap between existing models and, in doing so, we have unveiled critical new properties of this type of signaling cascades. A key feature of our new model is that a negative feedback emerges naturally, exerted between each cycle and its predecessor. Due to this negative feedback, the system displays damped temporal oscillations under constant stimulation and, most important, propagates perturbations both forwards and backwards. This last attribute challenges the widespread notion of unidirectionality in signaling cascades. Concrete examples of applications to MAPK cascades are discussed. All these properties are shared by the complete mechanistic description and our simplified model, but not by previously derived phenomenological models of signaling cascades.

  15. Human-induced trophic cascades along the fecal detritus pathway.

    Directory of Open Access Journals (Sweden)

    Elizabeth Nichols

    Full Text Available Human presence and activity in tropical forest is thought to exert top-down regulation over the various 'green-world' pathways of plant-based foodwebs. However, these effects have never been explored for the 'brown-world' pathways of fecal-detritus webs. The strong effects of humans on tropical game mammals are likely to indirectly influence fecal detritivores (including Scarabaeine dung beetles, with subsequent indirect impacts on detrivore-mediated and plant-facilitating detrital processes. Across a 380-km gradient of human influence in the western Brazilian Amazon, we conducted the first landscape-level assessment of human-induced cascade effects on the fecal detritus pathway, by coupling data on human impact, game mammal and detritivore community structure, and rate measurements of a key detritus process (i.e. dung beetle-mediated secondary seed dispersal. We found evidence that human impact indirectly influences both the diversity and biomass of fecal detritivores, but not detritivore-mediated processes. Cascade strength varied across detritivore groups defined by species' traits. We found smaller-bodied dung beetles were at higher risk of local decline in areas of human presence, and that body size was a better predictor of cascade structure than fecal resource manipulation strategy. Cascade strength was also stronger in upland, unflooded forests, than in seasonally flooded forests. Our results suggest that the impact of human activity in tropical forest on fecal-detritus food web structure is mediated by both species' traits and habitat type. Further research will be required to determine the conditions under which these cascade effects influence fecal-detritus web function.

  16. Development of a New Cascade Voltage-Doubler for Voltage Multiplication

    OpenAIRE

    Arash Toudeshki; Norman Mariun; Hashim Hizam; Noor Izzri Abdul Wahab

    2014-01-01

    For more than eight decades, cascade voltage-doubler circuits are used as a method to produce DC output voltage higher than the input voltage. In this paper, the topological developments of cascade voltage-doublers are reviewed. A new circuit configuration for cascade voltage-doubler is presented. This circuit can produce a higher value of the DC output voltage and better output quality compared to the conventional cascade voltage-doubler circuits, with the same number of stages.

  17. Development of GaN/AlGaN Terahertz Quantum Cascade Laser

    Science.gov (United States)

    2008-11-19

    AFOSR-Taiwan Nanoscience Initiative Project Final Report Project Title Development of GaN /AlGaN Terahertz Quantum Cascade Laser...DATES COVERED 14-06-2007 to 13-06-2008 4. TITLE AND SUBTITLE Development of GaN -Based Terahertz Quantum Cascade Laser 5a. CONTRACT NUMBER...the GaN /AlGaN active region for terahertz quantum cascade lasers using MOCVD system based on the quantum cascade structure proposed by Prof. Greg Sun

  18. Obtaining statistics of cascading line outages spreading in an electric transmission network from standard utility data

    CERN Document Server

    Dobson, Ian

    2015-01-01

    We show how to use standard transmission line outage historical data to obtain the network topology in such a way that cascades of line outages can be easily located on the network. Then we obtain statistics quantifying how cascading outages typically spread on the network. Processing real outage data is fundamental for understanding cascading and for evaluating the validity of the many different models and simulations that have been proposed for cascading in power networks.

  19. The Gamma-ray Sky with Fermi

    Science.gov (United States)

    Thompson, David

    2012-01-01

    Gamma rays reveal extreme, nonthermal conditions in the Universe. The Fermi Gamma-ray Space Telescope has been exploring the gamma-ray sky for more than four years, enabling a search for powerful transients like gamma-ray bursts, novae, solar flares, and flaring active galactic nuclei, as well as long-term studies including pulsars, binary systems, supernova remnants, and searches for predicted sources of gamma rays such as dark matter annihilation. Some results include a stringent limit on Lorentz invariance derived from a gamma-ray burst, unexpected gamma-ray variability from the Crab Nebula, a huge gamma-ray structure associated with the center of our galaxy, surprising behavior from some gamma-ray binary systems, and a possible constraint on some WIMP models for dark matter.

  20. Transplantação de baço de coelho com mixoma infeccioso na câmara anterior do ôlho da cobaia: sôbre a degeneração mixomatosa: inclusões intranucleares

    Directory of Open Access Journals (Sweden)

    C. Magarinos Torres

    1955-12-01

    Full Text Available Heterotranplantability of myxoma of rabbits was formely demonstrated when grafts from subcutaneous tissue in skin were used (MARGARINOS TÔRRES & RITA CARDOSOS, 1949. Better results are reported in this paper when grafts from the spleen of infected rabbits were employed. While grafts from normal spleen are almost completely absorbed in sixteen days, those from infected rabbits give origin to full-grown and vascularised tissue in which typical myxoma cells are predominant elements. Progressive growth of heterotransplantated myxoma cells is another similarity between infectious myxoma and malignant tumors. Formation of clear areas of circular contour (interference of a diffusible substance? associated to myxomatous degeneration is very conspicuous. Peculiar changes of the ground substance, reticular and collagenous fibers (globular swelling, rosary and bulb formation apparently related to myxomatous degeneration are described. An unexpected finding was the presence of typical intranuclear inclusion bodies in five among forty-eight grafts examined in the sixth day.