WorldWideScience

Sample records for cartoons as topic

  1. Holocaust Cartoons as Ideographs

    Directory of Open Access Journals (Sweden)

    Mahdiyeh Meidani

    2015-07-01

    Full Text Available The Holocaust cartoon competition of 2006 in Iran as an instance of social controversy has the potential to raise social and political arguments over various international and global issues. Through using McGee’s theory of ideograph and Edwards and Winkler’s theory of representative form, I identify the ideographs used in these cartoons and argue that the Holocaust cartoons function ideographically to portray Jews, Judaism, Palestine, Israel, Zionism, and the Holocaust. I explain how these controversial images function as representative characters and representative anecdotes and create different ideological interpretations of the Holocaust and associated issues, such as Israel–Palestine conflicts and Western freedom of speech. I argue that the cartoons suggest a connection between Nazism and Zionism, or the Nazi and Israeli regimes, by juxtaposing various elements and situations. I explain that the cartoons anecdotally refer to the Holocaust and represent it as myth or hoax used by Jews/Zionists to justify creation of the nation of Israel.

  2. The effect of Concept Cartoons to Academic Achievement in Instruction on the Topics of Divisibility

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    Abdullah Kaplan

    2015-08-01

    Full Text Available The purpose of this study was compared to the effect of academic achievement of concept cartoons and activity based instruction in instruction on the topics of divisibility rules and prime number. The matching- only design, which is quasi experimental design, is used in this study. It is applied sixth grade (N=42 students at a middle school in Gümüşhane in autumn term in academic year 2012- 2013. Different two groups participate for this study. One of the groups is selected control group, which is used activity based teaching, and another group is experimental group, which is used instruction by concept cartoon. SPSS 16.0 packet program is used in the analysis of the data in this study. The first the test of the normality, within pretest and posttest, is applied and was founded that the data is suitable the normality. Then t- test is applied between pretest data for reveal whether different significant or not. ANCOVA is applied covariate pretest results to post test data. The study reveal that there was a significant difference in academic achievement between those students taught with the two methods in favor of concept cartoon which means those students taught by concept cartoon performed better than those taught with activity based instruction. The finding also shows that concept cartoon method is an effective method of teaching topics of divisibility rules and prime numbers.

  3. Usage of Concept Cartoons in Teaching of Heat-Temperature Topic

    OpenAIRE

    Soner Yavuz; Cem Büyükekşi

    2011-01-01

    Misconceptions are common problems in chemistry education for teachers and students. These non-scientific ideas are reflecting students’ not consistent ideas, biases and daily-life experiences. This situation is an obstacle for students to learn chemistry topics. In the research, concept cartoons, which are intended to give information about heat and temperature subject, are used to get rid of misconceptions. Sample of the research is 35 students who are enrolled Elementary Science Education ...

  4. The cartoon controversy as a case of multiculturalrecognition

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2007-01-01

    The paper considers what ‘recognition' might mean in theory and which policies would in practice qualify as policies of recognition in relation to multicultural conflicts such as the ‘cartoon controversy' sparked by the publication of drawings of the Prophet Mohammad in the Danish Newspaper...... Jyllands-Posten. The paper provides a general theoretical account of recognition as a strictly political concept, including distinctions between different conceptions hereof, and asks whether the cartoon controversy can be described in these terms and what the relevant meaning of recognition might then be...

  5. Creating Cartoons to Promote Leaderships Skills and Explore Leadership Qualities

    Science.gov (United States)

    Smith, Latisha L.; Clausen, Courtney K.; Teske, Jolene K.; Ghayoorrad, Maryam; Gray, Phyllis; Al Subia, Sukainah; Atwood-Blaine, Dana; Rule, Audrey C.

    2015-01-01

    This document describes a strategy for increasing student leadership and creativity skills through the creation of cartoons. Creating cartoons engages students in divergent thinking and cognitive processes, such as perception, recall, and mental processing. When students create cartoons focused on a particular topic, they are making connections to…

  6. Violence in Children's Cartoons.

    Science.gov (United States)

    Jarrell, Sue

    A British 12-year-old boy died while imitating the heroic leaps of the cartoon character Batman. Tragic incidents stemming from cartoon imitation such as this one occur with alarming frequency. Still, many people choose to ignore violence in children's cartoons. Even some experts don't recognize that cartoons may be harmful. Researcher Wilbur…

  7. Foundation Flash Cartoon Animation

    CERN Document Server

    Jones, Tim; Rosson, Allan S

    2008-01-01

    One of Flash s most common uses is still animation for cartoons, games, advertising etc, and this book takes a fresh look at the topic, breaking it down pre-production, production, and post production, and looking at each section in detail, and covering topics such as storyboarding, character libraries and camera mechanics like no Flash book has before. The book is written by members of the Emmy award winning ANIMAX team, who have created work for clients such as Disney, AOL, Fox, WWE, ESPN, and Sesame workshop. This book is an opportunity for them to share their secrets, and is written to sui

  8. Audiovisual News, Cartoons, and Films as Sources of Authentic Language Input and Language Proficiency Enhancement

    Science.gov (United States)

    Bahrani, Taher; Sim, Tam Shu

    2012-01-01

    In today's audiovisually driven world, various audiovisual programs can be incorporated as authentic sources of potential language input for second language acquisition. In line with this view, the present research aimed at discovering the effectiveness of exposure to news, cartoons, and films as three different types of authentic audiovisual…

  9. Cartooning in Algebra and Calculus

    Science.gov (United States)

    Moseley, L. Jeneva

    2014-01-01

    This article discusses how teachers can create cartoons for undergraduate math classes, such as college algebra and basic calculus. The practice of cartooning for teaching can be helpful for communication with students and for students' conceptual understanding.

  10. Concept-Cartoons as a Tool to Evoke and Analyze Pupils Judgments in Social Science Education

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    Felix Fenske

    2011-10-01

    Full Text Available The following contribution makes an effort to place the concept-cartoon-method into the context of social science education. Concept-cartoons (CCs enable teachers to use the everyday life experiences and individual thoughts of the pupils as a positive enrichment tool within the learning processes. In this context, CCs are very suitable to function as a method to gain information about both the existing mental conceptions and the individual political judgment strategies. Through this, it is possible to put everyday life concepts and scientific knowledge in a constructive relationship, which finally enhances new learning objectives. First the article highlights the relevance of pupils’ and teachers` concepts for judgment processes. On this basis the method of CCs is introduced and evaluated.Der folgende Artikel beschäftigt sich mit den Möglichkeiten des methodischen Einsatzes von Concept-Cartoons im Rahmen sozialwissenschaftlichen Unterrichts. Als Instrumentarium zur Diagnose von Schülervorstellungen und individuellen Urteilsstrategien, bieten Comic-Cartoons den Lehrkräften die Möglichkeit, den Unterricht entlang dieser lernrelevanten Perspektiven zu gestalten. Durch die konstruktive Verknüpfung von Alltagskonzepten und Fachkonzepten können auf diese Weise neue Chancen für nachhaltige Lehr- und Lernprozesse erschlossen werden. Innerhalb dieses Beitrags wird zunächst die Bedeutung von Schülervorstellungen und vorfachlichen Urteilsstrategien für wirksamen sozialwissenschaftlichen Unterricht geklärt. Im Anschluss erfolgt eine Einführung in die Methode „Concept-Cartoons“. Abschließend werden exemplarisch drei von den Autoren gestaltete Cartoons vorgestellt.

  11. Cartoon Violence: Is It as Detrimental to Preschoolers as We Think?

    Science.gov (United States)

    Peters, Kristen M.; Blumberg, Fran C.

    2002-01-01

    Critically reviews research on effects of cartoon violence on children's moral understanding and behavior to enable early childhood educators and parents to make informed decisions about what constitutes potentially harmful television viewing. Focuses on preschoolers' limited comprehension of television content and relatively sophisticated moral…

  12. Exploring the Use of a Cartoon as a Learner Scaffold in the Planning of Scientific Investigations

    Science.gov (United States)

    Ramnarain, Umesh

    2012-01-01

    Despite curriculum imperatives, in South Africa and worldwide, for learners to have more autonomy in investigations, they remain largely teacher controlled with learners having only limited opportunities in planning. This design-based study explored how a cartoon can be employed in a Grade 9 Natural Sciences class in prompting learners to plan…

  13. Humor Production as a Function of Sex of Subject, Creativity, and Cartoon Content

    Science.gov (United States)

    Brodzinsky, David M.; Rubien, Janet

    1976-01-01

    High- and low-creative male and female college students were asked to devise humorous captions to cartoons containing sexual, aggressive, or neutral themes. Results indicate that males generated funnier captions than females to sexual and aggressive stimuli but not to neutral stimuli. Moreover, creativity was positively related to humor…

  14. Cartoons as a Teaching Tool: A Research on Turkish Language Grammar Teaching

    Science.gov (United States)

    Yaman, Havva

    2010-01-01

    The purpose of this study is to determine the effect of teaching by utilizing cartoons on student success in the Turkish language courses in primary school secondary level students. Working group of the study consists of 54 students studying in primary state school in Sakarya province Hendek district. In the study, the "Rule and Concept Test on…

  15. Are Aggressive Cartoons Really Funnier? A Replication

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    Stefan Stieger

    2014-10-01

    Full Text Available Research has found that more aggressive cartoons are perceived as funnier. The current study (N = 106; 16 cartoons examined this finding in more detail by additionally including painfulness and cleverness rankings of cartoons, and by examining possible moderating effects of different humor styles, self-esteem (explicit, implicit, and social desirability. Aggressive or painful cartoons were not perceived to be funnier, but were rated as having a cleverer punch line. Effects were only weakly correlated with participants’ humor styles, but were independent of self-esteem and social desirability. This suggests that aggressive cartoons are not in general perceived to be funnier than non-aggressive ones, and that there may be other moderators influencing this effect (e.g., the type of cartoons, definition of aggression and funniness, cultural aspects.

  16. Questioning Danish Cartoon Images

    DEFF Research Database (Denmark)

    Bojsen, Heidi

    2007-01-01

    The article discusses the language and satirical cartoons that describe African Danes in the Danish media. Starting with a brief historical overview of the social fonction of satirical cartoons in Denmark since the Reformation, it is discussed whether satire and satirical cartoons actually have s...

  17. Resolution of ambiguities in cartoons as an illustration of the role of pragmatics in natural language understanding by computers

    Energy Technology Data Exchange (ETDEWEB)

    Mazlack, L.J.; Paz, N.M.

    1983-01-01

    Newspaper cartoons can graphically display the result of ambiguity in human speech; the result can be unexpected and funny. Likewise, computer analysis of natural language statements also needs to successfully resolve ambiguous situations. Computer techniques already developed use restricted world knowledge in resolving ambiguous language use. This paper illustrates how these techniques can be used in resolving ambiguous situations arising in cartoons. 8 references.

  18. Psychological analysis of the cartoon as a form of independent work of students on discipline «Child psychology»

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    Elantseva S. A.

    2013-06-01

    Full Text Available The article considers the psychological analysis of the cartoon as one of the forms of organization of independent work of students on discipline «Child psychology» in the conditions of the competence-based approach in higher professional pedagogical edu-cation. We offer the technology of the organization of this forms of independent work of students. The example of the psychological analysis of the cartoon «Naughty bear» (director N. Berezovaya and the form of educational tasks.

  19. Psychological analysis of the cartoon as a form of independent work of students on discipline «Child psychology»

    OpenAIRE

    Elantseva S. A.

    2013-01-01

    The article considers the psychological analysis of the cartoon as one of the forms of organization of independent work of students on discipline «Child psychology» in the conditions of the competence-based approach in higher professional pedagogical edu-cation. We offer the technology of the organization of this forms of independent work of students. The example of the psychological analysis of the cartoon «Naughty bear» (director N. Berezovaya) and the form of educational tasks.

  20. The Teaching of Global Environmental Problems According to the Constructivist Approach: As a Focal Point of the Problem and the Availability of Concept Cartoons

    Science.gov (United States)

    Oluk, Sami; Ozalp, Isilay

    2007-01-01

    In this study, with selecting the focusing point of the problem as the availability of cartoons, the teaching of global environmental problems according to the constructivist theory is investigated on the 7th graders in rural areas. This study is restricted with the global warming (G), ozone depletion (O) and the acid rain (A) problems. In the…

  1. Product Placement in Cartoons

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    Irena Oroz Štancl

    2014-06-01

    Full Text Available Product placement is a marketing approach for integrating products or services into selected media content. Studies have shown that the impact of advertising on children and youth are large, and that it can affect their preferences and attitudes. The aim of this article is to determine the existing level of product placement in cartoons that are broadcast on Croatian television stations. Content analysis of cartoons in a period of one month gave the following results: in 30% of cartoons product placement was found; most product placement were visual ads, in 89%, however, auditory product placement and plot connection was also found. Most ads were related to toys and it is significant that even 65% of cartoons are accompanied by a large amount of products available on the Croatian market. This is the result of two sales strategies: brand licensing (selling popular cartoon characters to toys, food or clothing companies and cartoon production based on existing line of toys with the sole aim of making their sales more effective.

  2. The use of political cartoons and comic strips as a teaching resource and a pedagogical innovation in the teaching and learning of geography

    Directory of Open Access Journals (Sweden)

    Telma Lucia Bezerra Alves

    2013-06-01

    Full Text Available This study aimed to evaluate the use of political cartoons and comic strips as teaching resources in the teaching and learning of geography. Emphasis was given to Environmental Geography, correlating the content covered with selected images. Literature and field searches were conducted with students of the Geography degree from two Higher Education Institutions (HEIs in the city of Campina Grande-PB, where the critical-reflective analysis of graphic representations above was carried out. It was concluded that the use of political cartoons and comic strips is a strategic resource for teachers. These resources presented themselves as potentials to be explored and disseminated in the educational context because besides arousing students’ curiosity it makes them become interested in the content which is transmitted and built through it

  3. Roadrunner physics: using cartoons to challenge student preconceptions

    Science.gov (United States)

    Huxford, Rachael; Ridge, Mathew; Overduin, James; Selway, Jim

    The cartoon universe is governed by laws that differ radically from those in the real world, but also mirror some of our preconceptions of how the world ``should'' work. We all know that Wile E. Coyote will never be able to catch the Roadrunner with a fan attached to a sailboard, or an outboard motor submerged in a pail of water--but why, exactly? Can we attach some numbers to this knowledge? We have designed some classroom demonstrations accompanied by personal-response-type questions that use classic cartoon clips to challenge student thinking in introductory courses, prompting them to rediscover the truths of physics for themselves. We extend this idea to intermediate-level modern physics, showing that some phenomena in the cartoon universe can be reconciled with standard physics if the values of fundamental constants such as c , G and h differ radically from those in the real world. Such an approach can both heighten student interest and deepen understanding in various physics topics.

  4. Communicating the Value of Cartoon Art across University Classrooms: Experiences from the Ohio State University Billy Ireland Cartoon Library and Museum

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    McGurk, Caitlin

    2016-01-01

    This article is an exploration of the varying applications of comics and cartoon art as primary resources and pedagogical tools within the university setting. Following some background information on cartoon art forms including early American newspaper comics, nineteenth century humor serials, political cartoons and manga, the article explores how…

  5. Trialing Cartoons: Teachers' Attitudes towards Animation as an ELT Instructional Tool

    Science.gov (United States)

    DeCoursey, C. A.

    2012-01-01

    This paper explores the attitudes of teachers, as adult learners, towards learning to do animation. A part of popular culture which second-language students enjoy, until recently, animation has been technically too demanding for non-specialists to learn. Adult learners can experience e-learning as transformative, but also as a barrier. Thus,…

  6. Cartoons in the Classroom: A Largely Untapped Resource

    Science.gov (United States)

    Goulson, Cary F.

    1977-01-01

    The author recommends cartoons as a useful teaching medium for junior and senior high social studies. They clarify meanings of historical and current issues through symbolization and caricature. By sketching their own cartoons and writing about the details of others, students can increase their perception and understanding. (Author/AV)

  7. Othering: the cartoon controversy as a case of cultural racism in Denmark.

    OpenAIRE

    Capuani, Eugenio Maria; Arenas, Marisol

    2015-01-01

    Abstract In this last century a lot of world-conflicts not only crossed and damaged people and their life, but also influenced our culture and our modern view of the Others and the world. Even if Today apartheid doesn’t exist there are, in our society, many different types of Others that arise from and must struggle with segregation, religious discrimination, cultural racism, discrimination based on social status or racial belonging: that cannot be seen as a separated or better behavi...

  8. Modern machine learning techniques and their applications in cartoon animation research

    CERN Document Server

    Yu, Jun

    2013-01-01

    The integration of machine learning techniques and cartoon animation research is fast becoming a hot topic. This book helps readers learn the latest machine learning techniques, including patch alignment framework; spectral clustering, graph cuts, and convex relaxation; ensemble manifold learning; multiple kernel learning; multiview subspace learning; and multiview distance metric learning. It then presents the applications of these modern machine learning techniques in cartoon animation research. With these techniques, users can efficiently utilize the cartoon materials to generate animations

  9. "The Alternative of Williamsburg": A British Cartoon on Colonial American Violence.

    Science.gov (United States)

    Harper, John; And Others

    1996-01-01

    Utilizes a 1775 political cartoon as the centerpiece of a lesson on political controversy and violence in Colonial America. The cartoon, printed in Britain, lampooned the coercive measures directed at Tory merchants. Learning activities include an extensive analysis of the cartoon, discussions, and timelines. (MJP)

  10. Cartoon Network and its impact on behavior of school going children: A case of Bahwalpur, Pakistan

    OpenAIRE

    Hassan, Ali; Daniyal, Muhammad

    2013-01-01

    The objective of this study is to trace the impact on the behavior of the children after watching cartoon programs. Cartoon network is one of the most favorite cartoon channels for children. As cartoon network is 24 hours channel, so children spend most of their leisure time in front of it. It not only attracts the children through its contents but also inculcates some positive and negative habits in them. One of the main factors which influence the children while watching cartoons is violenc...

  11. Cartoons for Teaching Elementary Students about Bullying

    Science.gov (United States)

    Rule, Audrey C.; Logan, Stephanie R.; Kohler, Frank W.

    2012-01-01

    Bullying is a pressing concern in schools as many teachers are not being sufficiently prepared with curriculum and instructional strategies to prevent, mitigate, or halt it. This document presents classroom-tested cartoons created by graduate students that address the causes, effects, and ways of preventing or stopping bullying in an interesting…

  12. Topical and peripheral ketamine as an analgesic.

    Science.gov (United States)

    Sawynok, Jana

    2014-07-01

    Ketamine, in subanesthetic doses, produces systemic analgesia in chronic pain settings, an action largely attributed to block of N-methyl-D-aspartate receptors in the spinal cord and inhibition of central sensitization processes. N-methyl-D-aspartate receptors also are located peripherally on sensory afferent nerve endings, and this provided the initial impetus for exploring peripheral applications of ketamine. Ketamine also produces several other pharmacological actions (block of ion channels and receptors, modulation of transporters, anti-inflammatory effects), and while these may require higher concentrations, after topical (e.g., as gels, creams) and peripheral application (e.g., localized injections), local tissue concentrations are higher than those after systemic administration and can engage lower affinity mechanisms. Peripheral administration of ketamine by localized injection produced some alterations in sensory thresholds in experimental trials in volunteers and in complex regional pain syndrome subjects in experimental settings, but many variables were unaltered. There are several case reports of analgesia after topical application of ketamine given alone in neuropathic pain, but controlled trials have not confirmed such effects. A combination of topical ketamine with several other agents produced pain relief in case, and case series, reports with response rates of 40% to 75% in retrospective analyses. In controlled trials of neuropathic pain with topical ketamine combinations, there were improvements in some outcomes, but optimal dosing and drug combinations were not clear. Given orally (as a gargle, throat swab, localized peritonsillar injections), ketamine produced significant oral/throat analgesia in controlled trials in postoperative settings. Topical analgesics are likely more effective in particular conditions (patient factors, disease factors), and future trials of topical ketamine should include a consideration of factors that could predispose

  13. Climate Comics: polar research in a cartoon form

    Science.gov (United States)

    Courville, Z.; Carbaugh, S.; Defrancis, G.; Donegan, R.; Brown, C.; Perovich, D. K.; Richter-Menge, J.

    2013-12-01

    Climate Comics is a collaborative outreach effort between the Montshire Museum of Science, in Norwich, VT, the Cold Regions Research and Engineering Laboratory (CRREL) research staff, and freelance artist and recent graduate of the Center for Cartoon Studies in White River Junction, VT, Sam Carbaugh. The project involves the cartoonist, the education staff from the museum, and researchers from CRREL creating a series of comic books with polar science and research themes, including sea ice monitoring, sea ice albedo, ice cores, extreme microbial activity, and stories and the process of fieldwork. The aim of the comic series is to provide meaningful science information in a comic-format that is both informative and fun, while highlighting current polar research work done at the lab. The education staff at the Montshire Museum develops and provides a series of hands-on, inquiry-based activity descriptions to complement each comic book, and CRREL researchers provide science background information and reiterative feedback about the comic books as they are being developed. Here, we present the motivation for using the comic-book medium to present polar research topics, the process involved in creating the comics, some unique features of the series, and the finished comic books themselves. Cartoon illustrating ways snow pack can be used to determine past climate information.

  14. Interdependent relations between comic and animated cartoons

    OpenAIRE

    Eloyan, Armen

    2015-01-01

    Tiré du site Internet de Onestar Press: "Interdependent relations between comic and animated Cartoons. This book was produced in the context of Art Dubai's Marker, a curated not-for-profit gallery programme that concentrates each year on a particular theme or geography. (www.artdubai.ae/marker). The 2014 edition of Marker is curated by Slavs and Tatars and takes Central Asia and the Caucasus as its focus.".

  15. Repurposing celecoxib as a topical antimicrobial agent

    Directory of Open Access Journals (Sweden)

    Mohamed N. Seleem

    2015-07-01

    Full Text Available There is an urgent need for new antibiotics and alternative strategies to combat multidrug-resistant bacterial pathogens, which are a growing clinical issue. Repurposing existing approved drugs with known pharmacology and toxicology is an alternative strategy to accelerate antimicrobial research and development. In this study, we show that celecoxib, a marketed inhibitor of cyclooxygenase-2, exhibits broad-spectrum antimicrobial activity against Gram-positive pathogens from a variety of genera, including Staphylococcus, Streptococcus, Listeria, Bacillus, and Mycobacterium, but not against Gram-negative pathogens. However, celecoxib is active against all of the Gram-negative bacteria tested, including strains of, Acinetobacter, and Pseudomonas, when their intrinsic resistance is artificially compromised by outer membrane permeabilizing agents such as colistin. The effect of celecoxib on incorporation of radioactive precursors into macromolecules in Staphylococcus aureus was examined. The primary antimicrobial mechanism of action of celecoxib was the dose-dependent inhibition of RNA, DNA, and protein synthesis. Further, we demonstrate the in vivo efficacy of celecoxib in a methicillin-resistant S. aureus (MRSA infected Caenorhabditis elegans whole animal model. Topical application of celecoxib (1 and 2% significantly reduced the mean bacterial count in a mouse model of MRSA skin infection. Further, celecoxib decreased the levels of all inflammatory cytokines tested, including tumor necrosis factor-α, interleukin-6, interleukin-1 beta, and monocyte chemo attractant protein-1 in wounds caused by MRSA infection. Celecoxib also exhibited synergy with many conventional antimicrobials when tested against four clinical isolates of S. aureus. Collectively, these results demonstrate that celecoxib alone, or in combination with traditional antimicrobials, has a potential to use as a topical drug for the treatment of bacterial skin infections.

  16. Role of Concept Cartoons in Chemistry Learning

    Science.gov (United States)

    Gafoor, Kunnathodi Abdul; Shilna, V.

    2013-01-01

    Cartoons are valuable aids that prompt interest and foster genuine student engagement in the classroom. Cartoons are part of a much larger effort to introduce rare and amusing activities to boost learning and student participation. Concept cartoons are visual tools composed of three or more characters' proposing ideas, discussing or thinking…

  17. Method for Face-Emotion Retrieval Using A Cartoon Emotional Expression Approach

    Science.gov (United States)

    Kostov, Vlaho; Yanagisawa, Hideyoshi; Johansson, Martin; Fukuda, Shuichi

    A simple method for extracting emotion from a human face, as a form of non-verbal communication, was developed to cope with and optimize mobile communication in a globalized and diversified society. A cartoon face based model was developed and used to evaluate emotional content of real faces. After a pilot survey, basic rules were defined and student subjects were asked to express emotion using the cartoon face. Their face samples were then analyzed using principal component analysis and the Mahalanobis distance method. Feature parameters considered as having relations with emotions were extracted and new cartoon faces (based on these parameters) were generated. The subjects evaluated emotion of these cartoon faces again and we confirmed these parameters were suitable. To confirm how these parameters could be applied to real faces, we asked subjects to express the same emotions which were then captured electronically. Simple image processing techniques were also developed to extract these features from real faces and we then compared them with the cartoon face parameters. It is demonstrated via the cartoon face that we are able to express the emotions from very small amounts of information. As a result, real and cartoon faces correspond to each other. It is also shown that emotion could be extracted from still and dynamic real face images using these cartoon-based features.

  18. 30 September 2015: 10 years after the Danish Muhammad cartoons controversy

    DEFF Research Database (Denmark)

    Vinding, Niels Valdemar

    2015-01-01

    , the debate continues in Denmark and it focuses on three things; firstly, what is the state of freedom of expression today in Denmark especially when it comes to religion, and in relation, secondly, should editors re-run the cartoons on the occasion of the 10 year anniversary, and thirdly should teachers......Today, 30 September 2015, we observe the 10 year anniversary of the publications of 12 editorial cartoons in Jyllands-Posten. The cartoons were originally commissioned as an attempt to contribute to the debate about legitimate criticism of Islam, freedom of speech and self-censorship. Today...

  19. Cartoons Influence towards Violence and Aggression in School Age Children in Nigeria

    OpenAIRE

    Odukomaiya, Elizabeth Ibukunoluwa

    2014-01-01

    ABSTRACT: The aim of this study is to explore how violence and aggression in cartoon affects school age children in Nigeria. The reason for embarking on this research is to know whether and to what extent cartoon on television makes school age children (both male and female) violent and aggressive. Children are exposed to cartoon at their tender age (4-12). Though it serves as a means of entertainment to them, children learn faster than adults, and their re-enactment of media messages is unri...

  20. Young People's Readings of a Political Cartoon and the Concept of Multimodal Literacy

    Science.gov (United States)

    El Refaie, Elisabeth; Horschelmann, Kathrin

    2010-01-01

    This article uses young people's responses to a newspaper cartoon as a way of exploring the concept of multimodal literacy. The discussion draws on data from a study which aimed to elicit the geopolitical views of 16-19-year-olds in a multi-ethnic British city by using cartoons as a way of encouraging them to talk about their thoughts and feelings…

  1. Children'S experience of three types of cartoon at two age levels.

    Science.gov (United States)

    Björkqvist, K; Lagerspetz, K

    1985-01-01

    Three cartoons were shown to 87 children at two age levels: 5-6 years, and 9 years. The children's experience was assessed in interviews. The younger children experienced the cartoons in a fragmentary manner and not as a continuous story, understood less of the cartoons, and tended to base their moral judgements of a character's behaviour on whether or not they identified with that character. Six months later, the younger children remembered best those scenes that had made them the most anxious earlier. A subgroup of children with abundant aggressive fantasies had a lower level of moral reasoning than the other children, preferred violent scenes, became less anxious while watching them and tended to give illogical explanations for the behaviour of the cartoon characters. The degree of anxiety provoked by a cartoon depended not on the amount of explicit violence shown but on the way the violence was presented. One cartoon, which contained no explicit violence, was considered the most frightening one due to its sound effects. PMID:25825063

  2. Topical dexketoprofen as a cause of photocontact dermatitis.

    Science.gov (United States)

    López-Abad, R; Paniagua, Ma J; Botey, E; Gaig, P; Rodriguez, P; Richart, C

    2004-01-01

    We reported on the case of a patient who developed a cutaneous eruption in a photoexposed area 1 week after a continous topical treatment with dexketoprofen (Enangel). Photopatch tests were positive for dexketoprofen, ketoprofen and piketoprofen and patch test was positive for piketoprofen. Control photopatch testing with dexketoprofen in 15 healthy volunteers was negative. Dexketoprofen, ketoprofen and piketoprofen are non-steroidal anti-inflamatory drugs (arylpropionic acid derivatives) often used as topical anti-inflammatory agents. It appears that the benzophenone moiety of their chemical structure is the cause of their photosensitivity and cross-photoreaction.

  3. LIQUID CRYSTAL AS ACCELERANT IN DRUG ABSORPTION FROM TOPICAL FORMULATIONS

    Directory of Open Access Journals (Sweden)

    Trivedi Nirali

    2011-04-01

    Full Text Available Topical drug delivery has been one of the major research fields in the area of drug therapy for last few decades. However inspite of its large therapeutic potential market success has been limited. It provides the several advantages over the oral drug delivery. Percutaneous absorption involves the passage of the drug molecule from the skin surface into the stratum corneum under the influence of a concentration gradient and its subsequent diffusion through the stratum corneum and underlying epidermis, through the dermis, and into the blood circulation. Liquid crystal phase has emerged as a novel material for preparation of topical drug delivery systems. It fulfills the requirements for making drug loading and drug absorption faster from the site of application of topical formulations. Liquid crystal has got many phases in itself which can be further exploited to get a better and more efficient drug delivery system. Also a variety of areas in medical and electronics streamline can find its application. There is also a wide scope in respect to the methods by which these liquid crystals can be prepared. Different methods give rise to different kinds of liquid crystals. Topical formulations have emerged as a very useful drug delivery system as it bypasses the first pass metabolism. Also the absorption of drugs depends on the percutaneous absorption of drug from the area of application. Hence it’s required to choose such a vehicle which enhances the absorption of drug from the formulation.

  4. TV Cartoons: Do Children Think They Are Real?

    Science.gov (United States)

    Middleton, Yvette; Vanterpool, Sandra M.

    Noting the research finding that children watch an average of 20 to 25 violent acts per hour on Saturday morning cartoons, this paper discusses cartoon violence and presents the findings of a survey examining children's ability to differentiate between real and fantasy violence in television cartoons and the impact of such violence. Participating…

  5. Sex Role Stereotyping in Saturday Morning Cartoon Shows.

    Science.gov (United States)

    Mayes, Sandra L.; Valentine, K. B.

    1979-01-01

    Explores the role children's cartoon programs may play in forming sex role identities in children through the presentation of sex-typed personality attributes of the cartoon characters. Fourteen dependent variables of cartoon character personality were analyzed by sex of the character and sex of the viewer. (JVP)

  6. Looking at Elections through the Cartoonist's Eye. Teaching with Cartoons.

    Science.gov (United States)

    Heitzman, W. Ray

    2000-01-01

    Provides a taxonomy of subskills needed to interpret political cartoons. Focuses on two of the subskills (caricature and symbolism) in detail. Includes copies of political cartoons that all pertain to the electoral process, guidelines for selecting cartoons for classroom use, and a list of resources. (CMK)

  7. The Effect of Aggressive Cartoons: Children's Interpersonal Play.

    Science.gov (United States)

    Hapkiewicz, Walter G.; Roden, Aubrey H.

    Sixty second grade children were randomly assigned to same sex pairs and each pair was randomly assigned to one of three treatment groups: aggressive cartoon, nonaggressive cartoon, and no cartoon. Results indicated that there was no difference among the groups on measures of interpersonal aggression although boys exhibited significantly more…

  8. The “Nationalization” of Oil Painting and Cartoons

    Institute of Scientific and Technical Information of China (English)

    LI Nan; Tan Mingxiang; Sun Hong

    2013-01-01

    process of history, Chinese figure painting s changed dramatically.For exam-ple, Xu Beihong, Jiang Zhaohe, Ye Qianyu, Li Hu, Lu Chen, Liu Dawei, Shi Guoliang, He Jiay-ing, etc.absorbed the techniques of western oil painting, and created a new system of Chinese fig-ure painting that is quite different from original Chinese figure painting.Hence, the “nationaliza-tion” of painting existed in name only. 2.Direction of Cartoon The “nationalization” of cartoons reflects the needs of popularization and education in a specific period of China, and is a product stimulated by the“nationalization” of oil painting.In the period of the Great Leap Forward and planned economy after the liberation , “nationalization” was defined as“a mature symbol of art and literature of an era and a class.” Even though education -oriented cartoons have been changed into “artistic car-toons” and received many prizes in international competitions through the efforts of the old genera-tion of cartoon artists, it still strayed away from the entertainment function of cartoons .For a long peri-od, cartoon animations could not reflect reality, that “constraint our creative mind , and the themes of cartoon films were limited in a very narrow cir-cle.” This created five problems as follows: 1) Lack of themes which reflected reality and the future: Traditional folk stories, historical sto-ries, myths, etc.are not able to satisfy present - day teen -agers’ education.Children not only need to have an education in ancient cultural con-cepts, but they also need to think about their real life, including imaging and explorating the fu-ture technological society. 2) Misdirection in the restoration of historical materials : the repeated interpretation of history limits the creativity and imagination of cartoons. Historical material must be combined with a realis-tic spirit.Only innovation based on tradition is the key for the cartoon’ s success. 3) The differences between ancient arts

  9. Resolution Independent 2D Cartoon Video Conversion

    Directory of Open Access Journals (Sweden)

    MSF. Fayaza

    2016-03-01

    Full Text Available This paper describes a novel system for vectorizing 2D raster cartoon. The output videos are the resolution independent, smaller in file size. As a first step, input video is segment to scene thereafter all processes are done for each scene separately. Every scene contains foreground and background objects so in each and every scene foreground background classification is performed. Background details can occlude by foreground objects but when foreground objects move its previous position such occluded details exposed in one of the next frame so using that frame can fill the occluded area and can generate static background. Classified foreground objects are identified and the motion of the foreground objects tracked for this simple user assistance is required from those motion details of foreground object’s animation generated. Static background and foreground objects segmented using K-means clustering and each and every cluster’s vectorized using potrace. Using vectored background and foreground object animation path vector video regenerated.

  10. French Higher Education: A Cartoon Essay

    Science.gov (United States)

    Hall, Matthew Henry

    2012-01-01

    In this cartoon essay, the author shares his experience from a travel to Paris to see the French higher education system. From his travel, he learned that in France, "degree" inflation may be an issue, but not grade inflation. On the flight home, the author reflects how French and American academics answer one question about the state of higher…

  11. Reflections on Jokes and Cartoons about Suicide

    Science.gov (United States)

    Lester, David

    2012-01-01

    This article is intended to engage others in a dialogue about the role and meaning of jokes about suicide. Types of jokes involving suicide are examined to distinguish the different types of humor involved. A sample of 118 recent political cartoons in an online website was downloaded, of which 73 concerned suicide bombers. Examples of suicide…

  12. A Cartoon History of Soil Microbiology.

    Science.gov (United States)

    Coyne, M. S.

    1996-01-01

    Describes the use of cartoons in presenting a historical perspective of soil microbiology that makes this information more entertaining to introductory students. Presents basic historical facts and major accomplishments of the pioneering soil microbiologists in a factual but tongue-in-cheek survey. (Author/JRH)

  13. Solar thermal energy as a topic in secondary mathematics classrooms

    Energy Technology Data Exchange (ETDEWEB)

    Brinkmann, A.; Brinkmann, K. [EnviPro Environmental Process Engineering Prof. Dr. Klaus Brinkmann, Iserlohn (Germany)

    2004-07-01

    One of the most effective methods to achieve a sustainable change of our momentary existing power supply system to a system mainly based on renewable energy conversion is the education of our children. For this purpose the compulsory school subject mathematics appears to be suitable. In order to promote renewable energy issues in mathematics classrooms, the authors have developed a special didactical concept to open this field for students, as well as for their teachers. The aim of this paper is to present firstly an overview of our concept and secondly examples of problems to the special topic of solar thermal energy, developed on the basis of our concept. (orig.)

  14. Psicopatologia nas histórias em quadrinhos e cartoons Psychopathology in newspaper cartoons and comic strips

    Directory of Open Access Journals (Sweden)

    Tomás Moraes Abreu Bonomi

    2010-01-01

    psychopathology are addressed. METHOD: A sample of 1,883 cartoons and comic strips published in a six month period by the newspaper Folha de São Paulo and the New York Times was collected from February first to July 31 of 2007. Thousand and twenty-two strips were by Brazilian authors, 293 by American authors published by Folha de São Paulo and 568 by the New York Times. Categories were created to classify them. RESULTS: Among Brazilian authors, 75.3% of the strips deal with health related themes. This category is divided into: physical health (12.9% and mental health (62.4%. On the other hand, the American authors seldom address the theme health. Their preference was to social customs and habits and political issues, specially related to war. When health was presented the issues were mainly related to obesity and the lack of adequate care to the war veterans. DISCUSSION: Comic books and strips show that violence, poverty and especially health are major concerns of the Brazilians comics authors, whereas the American comics and cartoons deal mainly with election politics and the war. The Brazilian stories address the topic of mental health more frequently, yet the portrayed psychopathological signs and symptoms are basically the same as Americans'. Brazilian stories also cover a greater variety of topics related to physical health. The American ones deal mostly with obesity related themes. Through humor, the comics call attention to the problems of our societies. In Brazil especially those of mental health and in United States the Iraq and Afghanistan war.

  15. Political Cartoons in the EFL and American Studies Classroom

    Directory of Open Access Journals (Sweden)

    Christianna Stavroudis

    2014-10-01

    Full Text Available Political cartoons are anything but innocent caricatures. They have been described as “a confrontational art form” (Oliphant 25, as “purposefully designed to elicit strong emotions and reactions from readers” (Long, Bunch, and Lloyd 651, and as “among the more extreme forms of expression” (Long, Bunch, and Lloyd 651. Stories abound with the harsh punishments endured by political cartoonists under oppressive regimes. One might even say that what allows liberal and conservative American cartoonists to feel any sense of solidarity with one another is their bond through the First Amendment and their belief in the democratic enterprise that is criticizing government.

  16. Preliminary Examination of a Cartoon-Based Hostile Attributional Bias Measure for Urban African American Boys

    Science.gov (United States)

    Leff, Stephen S.; Lefler, Elizabeth K.; Khera, Gagan S.; Paskewich, Brooke; Jawad, Abbas F.

    2014-01-01

    The current study illustrates how researchers developed and validated a cartoon-based adaptation of a written hostile attributional bias measure for a sample of urban, low-income, African American boys. A series of studies were conducted to develop cartoon illustrations to accompany a standard written hostile attributional bias vignette measure (Study 1), to determine initial psychometric properties (Study 2) and acceptability (Study 3), and to conduct a test-retest reliability trial of the adapted measure in a separate sample (Study 4). These studies utilize a participatory action research approach to measurement design and adaptation, and suggest that collaborations between researchers and key school stakeholders can lead to measures that are psychometrically strong, developmentally appropriate, and culturally sensitive. In addition, the cartoon-based hostile attributional bias measure appears to have promise as an assessment and/or outcome measure for aggression and bullying prevention programs conducted with urban African American boys. PMID:21800228

  17. "Almost at War". The Mohammed Cartoon Crisis in Norwegian Media

    Directory of Open Access Journals (Sweden)

    Solveig Steien

    2008-04-01

    Full Text Available In January and February 2006, Norwegians witnessed the burning of their national flag in Palestine, the burning of Norwegian embassies and consulates in Syria, Lebanon and Iran; all simply because twelve Danish Mohammed cartoons from Jyllands-Posten had been reprinted in Norway; the cartoons were published in a marginal Christian conservative weekly newspaper, Magazinet, three months after their original appearance in Denmark. In February 2006 the Norwegian ISAF-forces in Afghanistan were attacked. This conflict had a surprising impact on domestic and foreign policy, and the Norwegian publication of the cartoons triggered a global escalation of the controversy; Norwegian newspapers wrote that the country was "almost at war". I have focused on how some leading Norwegian newspapers (Aften, Aftenposten, Dagbladet, Dagens Næringsliv, Dagsavisen and VG covered this unexpected crisis and studied the different discourses that became a substantial part of the media coverage. In my analysis I have used an overall approach of War versus Peace journalism. War and Peace journalism was not created as a concept for analysing media texts or photographs, but to provide practical tools for journalists in the field of conflict and war situations. Nevertheless, this approach gives an opportunity to examine the results of journalistic work and compare them with the press'es ideals and ethical codes. At the same time, the occurrence of discourses like "clash of civilisations", freedom of speech, "us" versus "them", i.e., "us" versus the Muslims, and the newspapers' choice of sources for their stories, seem to fit with a model of War and Peace journalism. The focus is on opinion materials like editorials and comments, as well as on domestic reports and reportage by correspondents. By analysing samples of articles I have tried to outline some areas where the concept of Peace versus War journalism still needs to be developed, in order to become a comprehensive or more

  18. Elastic vesicles as topical/transdermal drug delivery systems.

    Science.gov (United States)

    Choi, M J; Maibach, H I

    2005-08-01

    Skin acts a major target as well as a principle barrier for topical/transdermal drug delivery. Despite the many advantages of this system, the major obstacle is the low diffusion rate of drugs across the stratum corneum. Several methods have been assessed to increase the permeation rate of drugs temporarily. One simple and convenient approach is application of drugs in formulation with elastic vesicles or skin enhancers. Elastic vesicles are classified with phospholipid (Transfersomes((R)) and ethosomes) and detergent-based types. Elastic vesicles were more efficient at delivering a low and high molecular weight drug to the skin in terms of quantity and depth. Their effectiveness strongly depends on their physicochemical properties: composition, duration and application volume, and entrapment efficiency and application methods. This review focuses on the effect of elastic liposomes for enhancing the drug penetration and defines the action mechanism of penetration into deeper skin. PMID:18492190

  19. TOPICAL IMMUNIZATION AND THE USE OF CHITOSAN AS CARRIER

    Directory of Open Access Journals (Sweden)

    Vengadesh prabhu K

    2011-02-01

    Full Text Available With the technological advances in biomedical sciences and the better understanding of how the immune system works, new immunisation strategies and vaccine delivery options, such sprays, patches, and edible formulations have been developed. Needle-free delivery of vaccines has become a global priority. Transcutaneous immunisation (TCI, topical application of vaccine antigens to the skin, can elicit systemic antibody and T-cell responses, suggesting that this new technique may provide a means for vaccination without needles. TCI requires the use of an adjuvant such as cholera toxin added to a vaccine antigen, such as diphtheria toxoid, to induce antibodies to diphtheria toxoid. The adjuvant and antigen are thought to target Langerhans cells, potent antigen-presenting cells found in the superficial layers of the skin. TCI appears to be a highly practical technique for delivery of vaccines that provides unique access to the immune system.

  20. On the Embodiment of Cultural Specification of Western Cartoon Movies

    Institute of Scientific and Technical Information of China (English)

    张敏

    2015-01-01

    This study focus on the western culture embodied in cartoon movies.The main object is to help readers to know the characteristics of western culture through cartoon movies.With the enjoyment to the western cartoon movies,I discuss the definition of western culture.American culture is a representation of western culture,and there are many western culture elements in American culture,so I will mainly talk about American culture.And then,this thesis discusses some good cartoon movies,the incarnation of the western culture through them.The language,activities,and architectural style in cartoon movies show the American cultures well.People could have a better understand about their characteristics while enjoying the interesting,colorful,winning cartoons.

  1. "Kontsert porgandipirukale" kandideerib Cartoon d'Or'i auhinnale

    Index Scriptorium Estoniae

    2004-01-01

    Heiki Ernitsa ja Janno Põldma "Kontsert porgandipirukale" valiti Santiago de Compostelas (Hispaania) üleantava animafilmi auhinna Cartoon d'Or viie nominendi hulka. Loetletud ka konkureerivad filmid

  2. Review of topical beta blockers as treatment for infantile hemangiomas.

    Science.gov (United States)

    Painter, Sally L; Hildebrand, Göran Darius

    2016-01-01

    The treatment of infantile hemangiomas changed from the use of oral corticosteroids to oral propranolol on the serendipitous discovery of propanolol's clinical effectiveness in 2008. Since then, clinicians have begun to use topical beta blockers--in particular, timolol maleate 0.5% gel forming solution--with good effect. Topical beta blockers are now used for lesions with both deep and superficial components and those that are amblyogenic. When initiated in the proliferative phase of the lesion, the effectiveness of the treatment can be seen within days. There is no consensus on dosing, treatment bioavailability, or clinical assessment of lesions, but these are topics for future research.

  3. MICROSPONGES AS THE VERSATILE TOOL FOR TOPICAL ROUTE: A REVIEW

    Directory of Open Access Journals (Sweden)

    Archana Patel*, Pratik Upadhyay, Jatin Trivedi, Shreeraj Shah and Jaymin Patel

    2012-09-01

    Full Text Available The drug delivery technology landscape has become highly competitive and rapidly evolving. More and more developments in delivery systems are being integrated to optimize the efficacy and cost-effectiveness of the therapy. Conventional topical formulations are intended to work on the surface of the skin. Normally, upon application such formulations release their active ingredients and producing a highly concentrated layer of active ingredient that is quickly absorbed. Therefore, need exists for a system to increase the amount of time that an active ingredient is present either on skin surface as well as within the epidermis, at the same time, minimizing its transdermal penetration in the body. In recent times, microsponge delivery system (MDS has been successively addressed for the controlled release of drugs onto the epidermis with assurance that the drug remains chiefly localized and does not enter the systemic circulation in major amounts. Drug loaded microsponge consist of microporous beads, typically 10-25 μm in diameter that possess a versatility to entrap wide range of active agents. Microsponge Systems are based on microscopic, polymer-based microspheres that can suspend or entrap a wide variety of substances, and can then be incorporated into a formulated product such as a gel, cream, liquid or powder. Microsponge technology offers entrapment of ingredients and is believed to contribute towards reduced side effects, improved stability, increased elegance, and enhanced formulation flexibility. In addition, numerous studies have confirmed that microsponge systems are non-irritating, non-mutagenic, non-allergenic, and non-toxic. This review article covers methods of preparation, release mechanism, characterization and applications of microsponge delivery system with patent information and marketed formulations.

  4. "Ducks" and "Parrots": Elaboration, Duplication and Duplicity in a Cartoon Discourse Completion Test

    Science.gov (United States)

    Yoon, Yeo Bom; Kellogg, David

    2002-01-01

    Interviews, questionnaires and tests may fail as evaluations of pragmatic competence in a foreign language because they cannot reproduce contexts in sufficient detail and/or because they cannot constrain discourse options without contaminating the learner response. In this study a cartoon Discourse Completion Test (DCT) prompt was used, providing…

  5. Inventing Citizens During World War I: Suffrage Cartoons in "The Woman Citizen."

    Science.gov (United States)

    Ramsey, E. Michele

    2000-01-01

    Contributes to scholarship advancing the understanding of human communication by examining the rhetorical invention strategies of suffrage rhetoric in the cultural context of World War I. Shows how the political cartoons published in the mainstream Suffrage Movement's "The Woman Citizen" constructed women as strong, competent, and essential to the…

  6. Cartoons and Soap Operas: Popular Education in a Nova Scotia Fish Plant.

    Science.gov (United States)

    Bishop, Anne

    1988-01-01

    In a Nova Scotia fish plant, a group primarily made up of women used cartoons and soap operas to educate plant workers on union issues, domestic violence, and health issues, demonstrating the effectiveness of using people's own culture as a vehicle for their education. (SK)

  7. Semio-Pragmatic Analysis of Cartoons Discourse: A Step towards Semiotranslation

    Science.gov (United States)

    AlBzour, Naser Naif

    2011-01-01

    The primary concern of this study is to explore the subtle implications of the "Semiotranslation Approach vis-a-vis" analyzing the semiotic elements of discourse in Jordanian cartoons as creative artistic texts in which various signs manifest simultaneous interaction, thus achieving both entertainment and purposeful satire. Therefore, the…

  8. The development of the cartoons crisis - a Danish perspective

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Schøler

    2010-01-01

    Gives an account of the Danish cartoons crisis of 2005-6, considers comparisons with the 'Rushdie affair' and points out some underlying questions of religion, law and the public space.......Gives an account of the Danish cartoons crisis of 2005-6, considers comparisons with the 'Rushdie affair' and points out some underlying questions of religion, law and the public space....

  9. Cartoon Violence and Children's Aggression: A Critical Review.

    Science.gov (United States)

    Hapkiewicz, Walter G.

    This paper reviews ten studies on the effects of television cartoon violence on aggressive behavior in children and discusses possible reasons for the inconsistent results. Methodology and results of field and laboratory studies are compared, and study limitations are noted. The impact of cartoons is discussed in terms of human vs. animal…

  10. Arab Animated Cartoons : Mediating and Negotiating Notions of Identities

    NARCIS (Netherlands)

    Sayfo, O.A.

    2016-01-01

    This thesis is the first critical critical study of animated cartoon production in the Arab world. From the 1930s until the recent spread of online animations, animated cartoon production in the Arab world was the privilege of individuals and institutions with strong links to academic, media and pol

  11. The Earth Education by the traces of cartoons and comics: a vision of what was published in newspapers, available online, on five continents

    Science.gov (United States)

    Teixeira, Carlos; Paulo, Gallo; Nogueira, Maria Inês

    2015-04-01

    Communication's Purpose: Identify the artistic expression that uses the language of cartoons and comics for public communication, having as reference the Earth Education for a better planet sustainability. Object/Theme: Cartoons and comics published in newspapers, on five continents, made available in online version. Theoretical: This study is related to the assumption that the public communication of science by cartoons and comics constitute a textual genre, by the fact that they report scientific and complex themes presented in playful language, using humor and artistic traces accessible to the lay public. The scientific cartoons and comics aim to call public attention to scientific discoveries and science themes using illustrative chart features and short texts, both contextualized in a humorous structure. There are in the cartoons and comics, which are created to the public communication of science, an unintentionally pedagogical approach/formal, while transmitting information by unpretentious way and using graphic/artistic communication By the fact that in this specific format of communication there is knowledge being informed, the scientific cartoons and comics can contribute to the scientific empowerment of the society, in addition to being instruments that can also arouse scientific curiosity. The scientific cartoons and comics use objective language and short sentences, also employ words that may have a double meaning. It can be considered as an incentive for people's reflection. Method: It was analyzed cartoons and comics published in newspapers, made available in online version, published on five continents, in English, Portuguese and Spanish. Palavras-chave: science communication, public communication of science and technology; cartoons; comics

  12. Narrative Cartoons. Water in Africa.

    Science.gov (United States)

    McKoski, David

    The Water in Africa Project was realized over a 2-year period by a team of Peace Corps volunteers, World Wise Schools (WWS) classroom teachers, and WWS staff members. As part of an expanded, detailed design, resources were collected from over 90 volunteers serving in African countries, photos and stories were prepared, and standards-based learning…

  13. Alcohol-Related Content of Animated Cartoons: A Historical Perspective

    Directory of Open Access Journals (Sweden)

    Hugh eKlein

    2013-03-01

    Full Text Available This study, based on a stratified (by decade of production random sample of 1,221 animated cartoons and 4,201 characters appearing in those cartoons, seeks to determine the prevalence of alcohol-related content; how, if at all, the prevalence changed between 1930 and 1996 (the years spanned by this research; and the types of messages that animated cartoons convey about beverage alcohol and drinking in terms of the characteristics that are associated with alcohol use, the contexts in which alcohol is used in cartoons, and the reasons why cartoon characters purportedly consume alcohol.Approximately 1 cartoon in 11 was found to contain alcohol-related content, indicating that the average child or adolescent viewer is exposed to approximately 24 alcohol-related messages each week just from the cartoons that he/she watches. Data indicated that the prevalence of alcohol-related content declined significantly over the years. Quite often, alcohol consumption was shown to result in no effects whatsoever for the drinker, and alcohol use often occurred when characters were alone. Overall, mixed, ambivalent messages were provided about drinking and the types of characters that did/not consume alcoholic beverages.

  14. AN ALTERNATİVE METHOD İN SOCİAL STUDİES EDUCATİON: CARTOON

    OpenAIRE

    SİDEKLİ, Sabri; Sidekli, Sabri; Er, Harun; Yavaşer, Refika; Aydın, Erhan

    2014-01-01

    In this study, 6th grade social studies in the curriculum "life on Earth" in the teaching of the subject of "poles of the unit when changing climate" the use of students ' academic success of cartoon effect. The research is a study of an experimental pretest-posttest control group according to the model. Research the Mugla province a primary school 6th covers 65 students studying in class. Topic in the control group, the experimental group lecture method, if that meth...

  15. Notes toward a Rhetoric of Animation: "The Road Runner" as Cultural Critique.

    Science.gov (United States)

    Bruce, Douglas R.

    2001-01-01

    Uses the violence of "The Road Runner" cartoon series as a starting point for a mythico-rhetorical analysis of the message system contained in the cartoon. Explores how the cartoon re-enacts the myth of Sisyphus in the context of the post-World War II technological boom. Discusses insights into the meanings of cartoon violence, and into how media…

  16. "Porgandipirukas" ei võitnud Cartoon d'Ori

    Index Scriptorium Estoniae

    2004-01-01

    Heiki Ernitsa ja Janno Põldma "Kontsert porgandipirukale" valiti Santiago de Compostelas (Hispaania) üleantava animafilmi auhinna Cartoon d'Or viie nominendi hulka. Auhinna sai siiski Virgil Widrichi lühifilm "Kiire film" ("Fast Film") : Austria - Luksemburg 2003

  17. Bupivacaine Lozenge Compared with Lidocaine Spray as Topical Pharyngeal Anesthetic before Unsedated Upper Gastrointestinal Endoscopy

    DEFF Research Database (Denmark)

    Salale, Nesrin; Treldal, Charlotte; Mogensen, Stine;

    2014-01-01

    Unsedated upper gastrointestinal endoscopy (UGE) can induce patient discomfort, mainly due to a strong gag reflex. The aim was to assess the effect of a bupivacaine lozenge as topical pharyngeal anesthetic compared with standard treatment with a lidocaine spray before UGE. Ninety-nine adult...... with a lidocaine spray proved to be a superior option as topical pharyngeal anesthetic before an UGE....

  18. Recreational football as a health promoting activity: a topical review

    DEFF Research Database (Denmark)

    Krustrup, Peter; Aagaard, Per; Nybo, Lars;

    2010-01-01

    The present review addresses the physiological demands during recreational football training and the effects on central health variables that influence the risk of life-style diseases of young and middle-aged men. Recent studies have established that recreational football, carried out as small......-sided games can be characterized as having a high aerobic component with mean heart rates of 80-85% of maximum heart rate, which is similar to values observed for elite football players. In addition, the training includes multiple high-speed runs, sprints, turns, jumps and tackles, which provide a high impact...... on muscles and bones. Recreational football training in untrained men results in marked improvements in maximum aerobic power, blood pressure, muscle capillarization and intermittent exercise performance, and those effects are similar to interval training and more pronounced than moderate...

  19. Silver Nanoparticles as Real Topical Bullets for Wound Healing

    OpenAIRE

    Gunasekaran, Thirumurugan; Nigusse, Tadele; Dhanaraju, Magharla Dasaratha

    2012-01-01

    Nanotechnology is on the threshold of providing a host of new materials and approaches, revolutionizing the medical and pharmaceutical fields. Several areas of medical care are already profiting from the advantage that nanotechnology offers. Recently, silver nanoparticles are attracting interest for a clinical application because of its potential biological properties such as antibacterial activity, anti-inflammatory effects, and wound healing efficacy, which could be exploited in developing ...

  20. Bexarotene Topical

    Science.gov (United States)

    ... condition may improve as soon as 4 weeks after you begin to use topical bexarotene, or it may ... notice any improvement. Continue to use topical bexarotene after you notice improvement; your condition may continue to improve. ...

  1. Clinical use of topical thrombin as a surgical hemostat

    Directory of Open Access Journals (Sweden)

    Wesley K Lew

    2008-08-01

    Full Text Available Wesley K Lew1, Fred A Weaver21University of Southern California, Department of Surgery, Los Angeles, CA, USA; 2CardioVascular Thoracic Institute at the University of Southern California, Los Angeles, CA, USAAbstract: When surgical ligation of bleeding fails, or is not possible, surgeons rely on a number of hemostatic aids, including thrombin. This review discusses the history, pharmacology and clinical application of thrombin as a surgical hemostat. The initial thrombin was bovine in origin, but its use has been complicated by the formation of antibodies that cross react with human coagulation factors. This has been associated with life threatening bleeding and in some circumstances anaphylaxis and death. Human thrombin, isolated from pooled plasma of donors, has been developed in an effort to minimize these risks, but its downside is the potential of transmitting blood-borne pathogens and limited availability. Recently a recombinant thrombin has been developed and approved for use by the FDA. It has the advantage of being minimally antigenic and devoid of the risk if viral transmission. Thrombin is often used in conjunction with other hemostatic aids, including absorbable agents (like gelfoam, collagen, and cellulose, and with fibrinogen in fibrin glues. The last part of this review will discuss these agents in detail, and review their clinical applications.Keywords: bovine, recombinant, human, thrombin, antigenicity, antibodies

  2. Bruno Braunerde und die Bodentypen - Learning about soil diversity and soil functions with cartoon characters

    Science.gov (United States)

    Hofmann, Anett

    2015-04-01

    "Bruno Braunerde und die Bodentypen" is a German-language learning material that fosters discovery of soil diversity and soil functions in kids, teens and adults who enjoy interactive learning activities. The learning material consists of (i) a large poster (dimensions 200 x 120 cm) showing an imaginative illustrated landscape that could be situated in Austria, Switzerland or southern Germany and (ii) a set of 15 magnetic cards that show different soil cartoon characters, e.g. Bruno Braunerde (Cambisol), Stauni Pseudogley (Stagnic Luvisol) or Heidi Podsol (Podzol) on the front and a fun profession and address (linked to the respective soil functions) on the back side. The task is to place the soil cartoon characters to their 'home' in the landscape. This learning material was developed as a contribution to the International Year of Soils 2015 and is supported by the German, Austrian and Swiss Soil Sciences Societies and the Swiss Federal Office for the Environment. The soil cartoon characters are an adaptation of the original concept by the James Hutton Institute, Aberdeen, Scotland (www.hutton.ac.uk/learning/dirt-doctor).

  3. The role of topical antibiotics used as prophylaxis in surgical site infection prevention.

    LENUS (Irish Health Repository)

    McHugh, S M

    2012-02-01

    Compared with systemic antibiotic therapy, the topical or local delivery of an antibiotic has many potential advantages. However, local antibiotics at the surgical site have received very limited approval in any of the surgical prophylaxis consensus guidelines that we are aware of. A review of the literature was carried out through searches of peer-reviewed publications in PubMed in the English language over a 30 year period between January 1980 and May 2010. Both retrospective and prospective studies were included, as well as meta-analyses. With regard to defining \\'topical\\' or \\'local\\' antibiotic application, the application of an antibiotic solution to the surgical site intraoperatively or immediately post-operatively was included. A number of surgical procedures have been shown to significantly benefit from perioperative topical prophylaxis, e.g. joint arthroplasty, cataract surgery and, possibly, breast augmentation. In obese patients undergoing abdominal surgery, topical surgical prophylaxis is also proven to be beneficial. The selective use of topical antibiotics as surgical prophylaxis is justified for specific procedures, such as joint arthroplasty, cataract surgery and, possibly, breast augmentation. In selective cases, such as obese patients undergoing abdominal surgery, topical surgical prophylaxis is also proven to be beneficial. Apart from these specific indications, the evidence for use of topical antibiotics in surgery is lacking in conclusive randomized controlled trials.

  4. The role of topical antibiotics used as prophylaxis in surgical site infection prevention.

    LENUS (Irish Health Repository)

    McHugh, S M

    2011-04-01

    Compared with systemic antibiotic therapy, the topical or local delivery of an antibiotic has many potential advantages. However, local antibiotics at the surgical site have received very limited approval in any of the surgical prophylaxis consensus guidelines that we are aware of. A review of the literature was carried out through searches of peer-reviewed publications in PubMed in the English language over a 30 year period between January 1980 and May 2010. Both retrospective and prospective studies were included, as well as meta-analyses. With regard to defining \\'topical\\' or \\'local\\' antibiotic application, the application of an antibiotic solution to the surgical site intraoperatively or immediately post-operatively was included. A number of surgical procedures have been shown to significantly benefit from perioperative topical prophylaxis, e.g. joint arthroplasty, cataract surgery and, possibly, breast augmentation. In obese patients undergoing abdominal surgery, topical surgical prophylaxis is also proven to be beneficial. The selective use of topical antibiotics as surgical prophylaxis is justified for specific procedures, such as joint arthroplasty, cataract surgery and, possibly, breast augmentation. In selective cases, such as obese patients undergoing abdominal surgery, topical surgical prophylaxis is also proven to be beneficial. Apart from these specific indications, the evidence for use of topical antibiotics in surgery is lacking in conclusive randomized controlled trials.

  5. Decorative Line and Edge Extraction in Cartoon Images

    Directory of Open Access Journals (Sweden)

    Tiejun Zhang

    2013-04-01

    Full Text Available Decorative Lines and edges in a cartoon image are the most important elements to convey its semantic information. In this study, we propose a method to extract both decorative lines and edges of the cartoon image at the same time. Firstly, we use the Hessian matrix to compute the direction perpendicular to the decorative lines in the image. Then, non-maximum suppression is applied to the image’s second derivative of Gaussian to locate the possible decorative line’s center. Secondly, we use directional zero-crossing (the zero-crossing of the first Gaussian derivative on the precomputed direction to verify the existence of the decorative lines. Finally, decorative lines and the edges detected by non-maximum suppression on the first Gaussian derivative are fused together. The experimental results show that our method is more effective than other existed methods in literature for complicated cartoon images.

  6. Viscoelastic evaluation of topical creams containing microcrystalline cellulose/sodium carboxymethyl cellulose as stabilizer

    OpenAIRE

    Adeyeye, Moji Christianah; Jain, Ashwinkumar C.; Ghorab, Mohamed K. M.; Reilly, William J.

    2002-01-01

    The purpose of this study was to examine the viscoelastic properties of topical creams containing various concentrations of microcrystalline cellulose and sodium carboxymethyl cellulose (Avicel® CL-611) as a stabilizer. Avicel CL-611 was used at 4 different levels (1%, 2%, 4%, and 6% dispersion) to prepare topical creams, and hydrocortisone acetate was used as a model drug. The viscoelastic properties such as loss modulus (G), storage modulus (G), and loss tangent (tan δ) of these creams were...

  7. Reuse of clips in cartoon animation based on language instructions

    Institute of Scientific and Technical Information of China (English)

    WEI Bao-gang; ZHU Wen-hao; YU Jin-hui

    2006-01-01

    This paper describes a new framework for reusing hand-drawn cartoon clips based on language understanding approach. Our framework involves two stages: a preprocessing phase, in which a hand-drawn clip library with mixed architecture is constructed, and the on-line phase, in which the domain dependent language instructions parsing is carried out and clips in the clip library are matched by use of some matching values calculated from the information derived from instruction parsing. An important feature of our approach is its ability to preserve the artistic quality of clips in the produced cartoon animations.

  8. Témoigner, dénoncer, révulser : dessins de haine, XXe-XXIe siècles Hatred Exposed and Indicted in 20th and 21st Century Cartoons

    Directory of Open Access Journals (Sweden)

    Gilbert Millat

    2009-06-01

    Full Text Available The graphic satire label encompasses different trends in cartoon art, especially in Britain. Although the hate cartoon tradition actually represents a minority of published cartoons, it has been especially remarkable since the First World War. In various confrontational contexts, great artists feature in this tradition, ranging from Edmund Sullivan (1869-1933 to one of the leading cartoonists in the present generation, Steve Bell. This article focuses on aspects of the specific graphic rhetoric to be found in these images, and on their political impact as well as their echo in the media. The issues that cartoonists have recurringly been trying to bring up are also considered.

  9. The Muhammad cartoon controversy and the globalization of humor

    NARCIS (Netherlands)

    G. Kuipers

    2008-01-01

    At the 2006 conference of the International Society for Humor Studies (Danish University of Education, Copenhagen), several panels addressed issues raised by the Muhammad cartoon story. Among these, a colloquium organized by Paul Lewis and decorously titled "Transnational Ridicule and Response" focu

  10. Fast Mapping by Bilingual Children: Storybooks and Cartoons

    Science.gov (United States)

    Van Horn, Danielle; Kan, Pui Fong

    2016-01-01

    The purpose of this study was to examine the fast mapping skills in Spanish-English bilingual preschool children in two learning contexts: storybook reading and cartoon viewing. Eighteen typically developing Spanish-English bilingual preschool children completed a fast mapping task in Spanish (L1) and in English (L2). In 4 different sessions, each…

  11. Saturday Morning Cartoons and Children's Perceptions of Social Reality.

    Science.gov (United States)

    Swan, Karen

    This paper examines the effects of Saturday morning cartoons on children's perceptions of social reality. The study consisted of an analysis of programs appearing between 8 and 11 o'clock in the morning on September 15, 1990, and June 9, 1992, focusing on the ethnicity, gender, and age of characters, the positive or negative portrayal of…

  12. Demonizing in Children's Television Cartoons and Disney Animated Films

    Science.gov (United States)

    Fouts, Gregory; Callan, Mitchell; Piasentin, Kelly; Lawson, Andrea

    2006-01-01

    The purpose of this study was to assess the prevalence of demonizing in the two major media that young children use (television and movies). Two content analyses were conducted using the animated feature films (n = 34) of the Walt Disney Company and after-school cartoons (n = 41). Each was coded for the modeling of the use of "evil" words when…

  13. The Description and Indexing of Editorial Cartoons: An Exploratory Study

    Science.gov (United States)

    Landbeck, Christopher Ryan

    2013-01-01

    While access to images in general has improved in the last 20 years, due to both advances in electronic storage and dissemination and to improvements in the intellectual provisions of them, access to editorial cartoons lags behind access to other types of images. While there have been piecemeal or ad hoc efforts to organize large cartoon…

  14. Topical cyclosporin as an alternative treatment for vision threatening blepharokeratoconjunctivitis: a case report

    Directory of Open Access Journals (Sweden)

    Ismail AS

    2012-06-01

    Full Text Available Abdul-Salim Ismail,1,2 Rohana Taharin,2 Zunaina Embong11Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, 2Department of Ophthalmology, Hospital Pulau Pinang, Jalan Resindensi, Pulau Pinang, MalaysiaAbstract: Here, a case of vision threatening blepharokeratoconjunctivitis that responded well to topical cyclosporin is reported. A 9-year-old Malay girl with a history of bilateral blepharokeratoconjunctivitis was regularly treated with lid scrubbing using diluted baby shampoo, fusidic acid gel, and topical steroids as well as an intermittent course of oral doxycycline for the past year. She developed acute onset bilateral eye redness associated with poor vision in her right eye. Both eyes showed marked diffuse hyperemic conjunctiva with corneal vascularization. The presence of corneal vascularization obscured the visual axis in the right eye. The condition did not improve with regular intensive lid hygiene using diluted baby shampoo, fusidic acid gel, and topical steroids. She was started on topical cyclosporin A 0.5% every 6 hours. There was a dramatic regression of corneal vascularization after 3 days on topical cyclosporin, with marked improvement in visual acuity. This is a single case in which cyclosporin improved the status of the ocular surface. A large cohort study is required to justify its effectiveness in treating blepharokeratoconjunctivitis and to test its potential as an alternative immunosuppressive agent in comparison to conventional corticosteroids.Keywords: blepharokeratoconjunctivitis, cyclosporin

  15. Lipid nano/submicron emulsions as vehicles for topical flurbiprofen delivery.

    Science.gov (United States)

    Fang, Jia-You; Leu, Yann-Lii; Chang, Chia-Chun; Lin, Chia-Hsuan; Tsai, Yi-Hung

    2004-01-01

    The application of lipid nano/submicron emulsions as topical drug carrier systems for the percutaneous absorption of flurbiprofen was investigated. The lipid emulsions were made up of isopropyl myristate (IPM), soybean oil, or coconut oil as the oil phase, egg lecithin as the predominant emulsifier, and double-distilled water as the external phase. Stearylamine (SA) and deoxycholic acid (DA) also were used to produce positively and negatively charged emulsions. To evaluate the physicochemical properties of the lipid emulsions, particle size by laser light scattering, the image of atomic force microscopy, and relaxation time values by Nuclear Magnetic Resonance (NMR) were determined. The in vitro permeation data showed that incorporation of SA significantly reduced the topical delivery of flurbiprofen. On the other hand, incorporation of DA exhibited no or a negligible effect on drug permeation. Enhancement of drug absorption was observed when adding oleic acid as part of the oil phase. The in vivo topical application of flurbiprofen from selected lipid emulsions showed a similar trend to the in vitro status. Furthermore, the intersubject variability was considerably reduced by lipid emulsions than by aqueous suspensions in both the in vitro and in vivo experiments. The irritant profiles of lipid emulsions showed that IPM elicited higher irritation than soybean oil. The incorporation of oleic acid also produced skin disruption. The results in the present study suggest the feasibility of lipid emulsions for the topical delivery of flurbiprofen.

  16. Watching cartoons activates the medial prefrontal cortex in children

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The medial prefrontal cortex (MPFC) of human adults is involved in attributing mental states to real human agents but not to virtual artificial characters. This study examined whether such differential MPFC activity can be observed in children who are more fascinated by cartoons than adults. We measured brain activity using functional magnetic resonance imaging (fMRI) while 10-year-old children watched movie and cartoon clips, simulating real and virtual visual worlds, respectively. We showed neuroimaging evidence that, in contrast to adults, the MPFC of children was activated when perceiving both human agents and artificial characters in coherent visual events. Our findings suggest that, around the age of 10 years, the MPFC activity in children is different from that in adults in that it can be spontaneously activated by non-human agents in a virtual visual world.

  17. Representation of the cartoon controversy on the U.S. newspapers

    OpenAIRE

    Yusuf Yüksel; Ayhan Akbulut

    2015-01-01

    Cartoon Crisis composed one of the most comprehensive international security problems of the last decade. A Danish newspaper, Jyllands-Posten, published 12 cartoons to satirize Prophet Mohammed in September 2005 which resulted in boycotts, anger and violent protest and thus a global conflict. The dispute over the cartoons has brought out the questions about the relations between the Islamic World and the West, the role of media on those relations, the limits of freedom of speech and right to ...

  18. Comparative study of liposomes, transfersomes and ethosomes as carriers for improving topical delivery of celecoxib.

    Science.gov (United States)

    Bragagni, Marco; Mennini, Natascia; Maestrelli, Francesca; Cirri, Marzia; Mura, Paola

    2012-01-01

    Topical administration of celecoxib proved to be an effective mean of preventing skin cancer development and improving anticancer drugs effectiveness in skin tumors treatment. The aim of this study was the development of an effective topical formulation of celecoxib, able to promote drug skin delivery, providing its in depth penetration through the skin layers. Three kinds of vesicular formulations have been investigated as drug carriers: liposomes containing a surfactant, or transfersomes and ethosomes, containing suitable edge activators. Firstly, the effect of membrane composition variations on the system performance has been evaluated for each vesicle type. Selected formulations were characterized for particle size, polydispersity index and encapsulation efficiency. The best formulations were subjected to ex vivo permeation studies through excised human skin. All vesicular formulations markedly (p ethosomes, respectively. In particular, ethosomes containing Tween 20 as edge activator not only showed the best vesicle dimensions and homogeneity, and the highest encapsulation efficacy (54.4%), but also enabled the highest increase in drug penetration through the skin, probably due to the simultaneous presence in their composition of ethanol and Tween 20, both acting as permeation enhancers. Therefore, among the various vesicular formulations examined in the study, Tween 20-ethosomes can be considered the most promising one as carrier for topical celecoxib applications aimed to prevent skin cancer development and increase the anticancer drugs effectiveness against skin tumors. PMID:23043648

  19. Comparative study of liposomes, transfersomes and ethosomes as carriers for improving topical delivery of celecoxib.

    Science.gov (United States)

    Bragagni, Marco; Mennini, Natascia; Maestrelli, Francesca; Cirri, Marzia; Mura, Paola

    2012-01-01

    Topical administration of celecoxib proved to be an effective mean of preventing skin cancer development and improving anticancer drugs effectiveness in skin tumors treatment. The aim of this study was the development of an effective topical formulation of celecoxib, able to promote drug skin delivery, providing its in depth penetration through the skin layers. Three kinds of vesicular formulations have been investigated as drug carriers: liposomes containing a surfactant, or transfersomes and ethosomes, containing suitable edge activators. Firstly, the effect of membrane composition variations on the system performance has been evaluated for each vesicle type. Selected formulations were characterized for particle size, polydispersity index and encapsulation efficiency. The best formulations were subjected to ex vivo permeation studies through excised human skin. All vesicular formulations markedly (p ethosomes, respectively. In particular, ethosomes containing Tween 20 as edge activator not only showed the best vesicle dimensions and homogeneity, and the highest encapsulation efficacy (54.4%), but also enabled the highest increase in drug penetration through the skin, probably due to the simultaneous presence in their composition of ethanol and Tween 20, both acting as permeation enhancers. Therefore, among the various vesicular formulations examined in the study, Tween 20-ethosomes can be considered the most promising one as carrier for topical celecoxib applications aimed to prevent skin cancer development and increase the anticancer drugs effectiveness against skin tumors.

  20. The Use of Cartoon to Investigate the Acquisition of Values in Primary Education: Case of Solidarity Values

    Directory of Open Access Journals (Sweden)

    Ali ERSOY

    2010-01-01

    Full Text Available The purpose of this study is to examine the solidarity values of primary school students through using cartoons as assessment materials. The data were gathered from three different primary schools in Eskisehir in May 2008. The participants of the study were 207 primary school students, 120 of whom were 4th graders, whereas 87 of whom were 5th graders. The data collection tools included a worksheet with a cartoon and three open ended questions. The data were analyzed through using NVivo 7.0 Qualitative Data Analysis Software Program with constant comparison and descriptive analysis methods. The findings revealed that the participants’ perceptions based on the solidarity values show differences. Their perceptions related to the solidarity values were as follows; there should be solidarity in the case of problem solving, the outcomes of the solidarity behavior should not be negative, solidarity could be provided for the immediate interests (i.e., winning an election etc., and solidarity could be provided in order to sustain discipline. Concerning the findings of the study, it can be claimed that cartoons could be used as an instrument to examine the cases inwhich social values, norms, and regulations are introduced in primary education.

  1. Automatic Tracing and Segmentation of Rat Mammary Fat Pads in MRI Image Sequences Based on Cartoon-Texture Model

    Institute of Scientific and Technical Information of China (English)

    TU Shengxian; ZHANG Su; CHEN Yazhu; Freedman Matthew T; WANG Bin; XUAN Jason; WANG Yue

    2009-01-01

    The growth patterns of mammary fat pads and glandular tissues inside the fat pads may be related with the risk factors of breast cancer.Quantitative measurements of this relationship are available after segmentation of mammary pads and glandular tissues.Rat fat pads may lose continuity along image sequences or adjoin similar intensity areas like epidermis and subcutaneous regions.A new approach for automatic tracing and segmentation of fat pads in magnetic resonance imaging (MRI) image sequences is presented,which does not require that the number of pads be constant or the spatial location of pads be adjacent among image slices.First,each image is decomposed into cartoon image and texture image based on cartoon-texture model.They will be used as smooth image and feature image for segmentation and for targeting pad seeds,respectively.Then,two-phase direct energy segmentation based on Chan-Vese active contour model is applied to partitioning the cartoon image into a set of regions,from which the pad boundary is traced iteratively from the pad seed.A tracing algorithm based on scanning order is proposed to accurately trace the pad boundary,which effectively removes the epidermis attached to the pad without any post processing as well as solves the problem of over-segmentation of some small holes inside the pad.The experimental results demonstrate the utility of this approach in accurate delineation of various numbers of mammary pads from several sets of MRI images.

  2. Final Technical Report summarizing Purdue research activities as part of the DOE JET Topical Collaboration

    Energy Technology Data Exchange (ETDEWEB)

    Molnar, Denes [Purdue Univ., West Lafayette, IN (United States). Dept. of Physics and Astronomy

    2015-09-01

    This report summarizes research activities at Purdue University done as part of the DOE JET Topical Collaboration. These mainly involve calculation of covariant radiative energy loss in the (Djordjevic-)Gyulassy-Levai-Vitev ((D)GLV) framework for relativistic A+A reactions at RHIC and LHC energies using realistic bulk medium evolution with both transverse and longitudinal expansion. The single PDF file provided also includes a report from the entire JET Collaboration.

  3. Microemulsions as vehicles for topical administration of voriconazole: formulation and in vitro evaluation.

    Science.gov (United States)

    El-Hadidy, Gladious Naguib; Ibrahim, Howida Kamal; Mohamed, Magdi Ibrahim; El-Milligi, Mohamed Farid

    2012-01-01

    This work was undertaken to investigate microemulsion (ME) as a topical delivery system for the poorly water-soluble voriconazole. Different ME components were selected for the preparation of plain ME systems with suitable rheological properties for topical use. Two permeation enhancers were incorporated, namely sodium deoxycholate or oleic acid. Drug-loaded MEs were evaluated for their physical appearance, pH, rheological properties and in vitro permeation studies using guinea pig skin. MEs based on polyoxyethylene(10)oleyl ether (Brij 97) as the surfactant showed pseudoplastic flow with thixotropic behavior and were loaded with voriconazole. Jojoba oil-based MEs successfully prolonged voriconazole release up to 4 h. No significant changes in physical or rheological properties were recorded on storage for 12 months at ambient conditions. The presence of permeation enhancers favored transdermal rather than dermal delivery. Sodium deoxycholate was more effective than oleic acid for enhancing the voriconazole permeation. Voriconazole-loaded MEs, with and without enhancers, showed significantly better antifungal activity against Candida albicans than voriconazole supersaturated solution. In conclusion, the studied ME formulae could be promising vehicles for topical delivery of voriconazole.

  4. Microemulsions as vehicles for topical administration of voriconazole: formulation and in vitro evaluation.

    Science.gov (United States)

    El-Hadidy, Gladious Naguib; Ibrahim, Howida Kamal; Mohamed, Magdi Ibrahim; El-Milligi, Mohamed Farid

    2012-01-01

    This work was undertaken to investigate microemulsion (ME) as a topical delivery system for the poorly water-soluble voriconazole. Different ME components were selected for the preparation of plain ME systems with suitable rheological properties for topical use. Two permeation enhancers were incorporated, namely sodium deoxycholate or oleic acid. Drug-loaded MEs were evaluated for their physical appearance, pH, rheological properties and in vitro permeation studies using guinea pig skin. MEs based on polyoxyethylene(10)oleyl ether (Brij 97) as the surfactant showed pseudoplastic flow with thixotropic behavior and were loaded with voriconazole. Jojoba oil-based MEs successfully prolonged voriconazole release up to 4 h. No significant changes in physical or rheological properties were recorded on storage for 12 months at ambient conditions. The presence of permeation enhancers favored transdermal rather than dermal delivery. Sodium deoxycholate was more effective than oleic acid for enhancing the voriconazole permeation. Voriconazole-loaded MEs, with and without enhancers, showed significantly better antifungal activity against Candida albicans than voriconazole supersaturated solution. In conclusion, the studied ME formulae could be promising vehicles for topical delivery of voriconazole. PMID:21696340

  5. Systemic absorption of topical steroids. Metabolic effects as an index of mild hypercortisolism.

    Science.gov (United States)

    Garden, J M; Freinkel, R K

    1986-09-01

    This study was undertaken to determine whether the commonly used treatment of psoriasis with potent topical glucocorticoids results in hypercortisolism and whether metabolic changes might provide a means for monitoring pharmacologic effects of excessive systemic absorption of glucocorticoids. Plasma cortisol, glucose, and insulin and circulating polymorphonuclear leukocytes were assessed under controlled conditions in five otherwise healthy patients with psoriasis (40% to 85% involvement) treated with topical desoximetasone, without occlusion. In all patients, there were rapid and sustained suppression of endogenous cortisol production, twofold to threefold increases in fasting insulin levels indicating insulin resistance, and elevated levels of polymorphonuclear leukocytes. Two patients also experienced reduced glucose tolerance. These findings suggest that application of potent corticosteroids to large areas of diseased skin results in sufficient systemic absorption to cause not only adrenal suppression but some degree of hypercortisolism with greater frequency and rapidity than has been suggested. Prospective monitoring of insulin-glucose relationships as a sensitive index of the metabolic effects of glucocorticoids may provide a means of assessing excess systemic absorption that is not predictable on the basis of adrenal suppression or circulating levels of the drug. Such prediction could have particular relevance in anticipating adverse clinical effects in the treatment of chronic skin disorders with potent topical glucocorticoids. PMID:3527074

  6. CARTOON USE FOR TEACHING TURKISH TO FOREIGNERS - YABANCILARA TÜRKÇE ÖĞRETİMİNDE ÇİZGİ FİLM KULLANIMI

    Directory of Open Access Journals (Sweden)

    Necmi AYTAN

    2015-08-01

    Full Text Available The aim of the research is to determine how the use of cartoons in a functional direction impacts on students’ achievement in teaching Turkish as a foreign language. One group post-test model is designed to be used in qualitative research. The sample group of the research consists of 15 participants who study Turkish at A1-elementary level as a foreign language at TOMER in Antalya International University. In the study for the purpose of collecting data question paper which contains the questions about the cartoon named ‘Oscar in the Desserts’ was used. Participants have watched short animated film called ‘Oscar in the Desserts’ twice. From watched visual to the screen photos which are belong to place questions asked were transferred to Power Point. Participants saw photos related to each sentence with a reminder function in the Power Point screen. In the result of this study ıt has been shown that the Turkish language teaching to the foreigners right visual materials such as cartoons are found useful when used functional in accordance with the age and level. In teaching Turkish as a foreign language courses; cartoons and other visuals have been found to provide a better understanding of the class they help to have an enjoyable lesson.

  7. Treating umbilical granuloma with topical clobetasol propionate cream at home is as effective as treating it with topical silver nitrate in the clinic

    DEFF Research Database (Denmark)

    Brødsgaard, Anne; Nielsen, Tove; Mølgaard, Ulla;

    2015-01-01

    AIM: There is a lack of evidence on the best treatment option for umbilical granuloma. The primary aim of this study was to compare three treatments for umbilical granuloma: standard treatment with topical silver nitrate, clobetasol propionate cream (0.05%) and ethanol wipes. The secondary aim......%) in the outpatient clinic, 30 infants had topical clobetasol propionate cream (0.05%) applied at home, and 34 infants received cleansing with ethanol wipes (82%) at home. RESULTS: Silver nitrate and clobetasol propionate cream (0.05%) were significantly superior to ethanol wipes, with shorter healing times...... and higher resolution rates (p = 0.0001). Healing time and resolution rates were identical for silver nitrate and clobetasol propionate cream (0.05%). Mild side effects were occasionally reported, all of which were self-limiting. CONCLUSION: Treating umbilical granuloma with topical clobetasol propionate...

  8. Using Cartoons to Teach about Perfectionism: Supporting Gifted Students' Social-Emotional Development

    Science.gov (United States)

    Rule, Audrey C.; Montgomery, Sarah E.

    2013-01-01

    Cartoon interpretation and production are teaching strategies that can assist students in a deeper understanding of concepts and practice of higher level thinking skills while motivating them through humor. This article presents an extended example of graduate students in an introductory course in gifted education creating humorous cartoons to…

  9. The Lack of Political Cartoons in the People's Republic of China.

    Science.gov (United States)

    Schnell, Jim

    Political cartoons do not appear in the government-controlled press in the People's Republic of China. The cartoons that do appear in newspapers are good-natured and lacking in any type of political message. Chinese civilization has a 5,000-year history that is grounded in feudalism and must be considered in any analysis of Chinese society. Since…

  10. Utility of Concept Cartoons in Diagnosing and Overcoming Misconceptions Related to Photosynthesis

    Science.gov (United States)

    Ekici, Fatma; Ekici, Erhan; Aydin, Fatih

    2007-01-01

    In this study, the effectiveness of concept cartoons in diagnosing and overcoming students' misconceptions related to photosynthesis subject was examined. Firstly, the literature has been thoroughly examined and misconceptions about photosynthesis subject have been listed and then grouped. Concept cartoons related to these groups have been…

  11. PROTAGONISM OF AMERICAN INDIANS IN WALTER LANTZ'S CARTOONS

    Directory of Open Access Journals (Sweden)

    Rafael Duarte Oliveira Venancio

    2011-06-01

    Full Text Available Condemned to a dubious media representation in early cinema through the novels of the late nineteenth century, the North American Indians never had a high profile in films of this period. However, an animator, Walter Lantz, has a high degree of characterization of Native Americans in his work. The aim of this paper is to study the role of Native Americans in these cartoons and analyze the social implications of these choices, using the concepts of apparatus and formula. Furthermore, the analysis will include a portrayal of the American media scene before and after Lantz, seeking disruptions and legacies.

  12. Topical Simvastatin as Host-Directed Therapy against Severity of Cutaneous Leishmaniasis in Mice

    Science.gov (United States)

    Parihar, Suraj P.; Hartley, Mary-Anne; Hurdayal, Ramona; Guler, Reto; Brombacher, Frank

    2016-01-01

    We recently demonstrated that statins mediate protection against intracellular pathogens, Mycobacterium tuberculosis and Listeria monocytogenes in mice. Here, we investigated the immunomodulatory potential of simvastatin as a topical or systemic host-directed drug therapy in controlling inflammatory responses in an experimental mouse model of cutaneous leishmaniasis caused by Leishmania major (LV39). In an ear infection model, topical application of simvastatin directly on established lesions significantly reduced severity of the disease reflected by ear lesion size and ulceration. The host protective effect was further accompanied by decreased parasite burden in the ear and draining lymph nodes in both BALB/c and C57BL/6 mice. Pre-treatment of these mice on a low-fat cholesterol diet and systemic simvastatin also reduced footpad swelling, as well as parasite burdens and ulceration/necrosis in the more robust footpad infection model, demonstrating the prophylactic potential of simvastatin for cutaneous leishmaniasis. Mechanistically, following L. major infection, simvastatin-treated primary macrophages responded with significantly reduced cholesterol levels and increased production of hydrogen peroxide. Furthermore, simvastatin-treated macrophages displayed enhanced phagosome maturation, as revealed by increased LAMP-3 expression in fluorescent microscopy and Western blot analysis. These findings demonstrate that simvastatin treatment enhances host protection against L. major by increasing macrophage phagosome maturation and killing effector functions. PMID:27632901

  13. Comparative Study between topical applications liposomally entrapped DNA repair enzymes and thymidine dinucleotide as radioprotectors

    International Nuclear Information System (INIS)

    The delivery of active agents to the skin by liposome carriers received great interest during the last three decades. This is based on their potential to enclose various types of biological materials and to deliver them to diverse cell types. Recent work suggests that liposomes as vehicles for topical drug delivery may be superior to conventional preparations. Also, topical application of DNA repair enzymes to irradiated skin increases the rate of repair of DNA potentially damaged cells. Moreover, thymidine dinucleotide is a new skin photo-protective agent against non-ionizing radiation through induction of DNA repair. Gamma irradiation can produce DNA damage in human skin. DNA mutations have an important role in the development of skin cancer and precancerous skin lesions. Albino rats were irradiated with Cobalt-60 gamma radiation with different doses (0.5, 1.5, 3 Gy), and were treated by either thymidine dinucleotide or liposomally entrapped DNA repair enzymes topically 24 hours before irradiation. Evaluation was done histopathologically by H and E stain. Computerized image analyzer using Masson's trichrome stain was also done. Gamma radiation produced epidermal thinning and dermal inflammatory cells together with collagen fragmentation and clumping in a dose-dependent manner. Comparing between both thymidine dinucleotide and liposomally entrapped DNA repair enzymes pretreated and irradiated rats. Low dose irradiation (0.5 Gy) together with previous drugs showed preservation of epidermis with no inflammatory cells and also it maintained the normal architecture of collagen bundles. However, they were ineffective with higher doses. In conclusion our results may suggest that the effects of gamma radiation on the skin at low dose could be minimized by the use of these drugs before exposure

  14. Learning about Teaching the Extracurricular Topic of Nanotechnology as a Vehicle for Achieving a Sustainable Change in Science Education

    Science.gov (United States)

    Blonder, Ron; Mamlok-Naaman, Rachel

    2016-01-01

    This study focused on teachers' transfer of a variety of teaching methods from a teaching module on nanotechnology, which is an example of a topic outside the science curriculum, to teaching topics that are part of the chemistry curriculum. Nanotechnology is outside the science curriculum, but it was used in this study as a means to carry out a…

  15. Evaluation of Topical Preparations Containing Curcuma, Acacia and Lupinus Extracts as an Anti-inflammatory Drugs

    Directory of Open Access Journals (Sweden)

    M M Hamzah

    2011-06-01

    Full Text Available Summary: This work was suggested on the basis of presence of curcuminoids in curcuma and the presence of flavonoidal constituent in acacia and lupinus. The aim of this study was to study their possible anti-inflammatory effect by separately formulation of the three extracts in a suitable gel formula for topical administration and comparison of the prepared gels with a standard gel in the market (diclosal Emulgel by using the carrageenan induced paw edema model in albino rats. The extracts were subjected to phytochemical screening tests using reported methods to determine the presence of various phytoconstituents. Gel formulation was prepared containing 8% of each extract separately in gel base, namely sodium carboxy methyl cellulose (NaCMC. The pharmacological screening revealed that percent reduction of edema produced by curcuma extract was 30.0%, by acacia extract was 4%, by ethanol fraction lupinus was 18% and by chloroform fraction lupinus was 11.3%, while diclofenac sodium topical gel produced 48% reduction of edema. Industrial relevance: Medicinal plants provide a host of chemical compounds, which have been optimized on the basis of their biological activities. Chemical compounds present in medicinal plants have shown great promise in the management of various inflammatory disorders and have continued to serve as alternative and complementary therapies. The present study will help the industry to produce herbal drug effective in the treatment of inflammation with less side effect and less costly when compared to the synthetic drugs.

  16. Topical tranexamic acid as a novel treatment for bleeding peptic ulcer: A randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Mandana Rafeey

    2016-01-01

    Full Text Available Background: Peptic ulcers are among the most common causes of upper gastrointestinal (GI bleeding in children. The standard care for GI bleeding is endoscopy for diagnostic and therapeutic purposes. We aimed to assess the effect of topical tranexamic acid (TXA via endoscopic procedures in children with GI bleeding caused by bleeding ulcers. Procedure: In this randomised controlled trial, 120 children were evaluated by diagnostic procedures for GI bleeding, of which 63 (30 girls, 33 boys aged 1-month to 15 years were recruited. The patients were randomly divided into case and control groups. In the case group, TXA was administered directly under endoscopic therapy. In the control group, epinephrine (1/10,000 was submucosally injected to the four quadrants of ulcer margins as the routine endoscopic therapy. In both groups, the patients received supportive medical therapy with intravenous fluids and proton pump inhibitor drugs. Results: The mean ± standard deviation age of the children was 5 ± 2.03 years. Rebleeding occurred in 15 (11.4% and 21 (9.8% patients in the case and control groups, respectively (P = 0.50. The frequency of blood transfusion episodes (P = 0.06 and duration of hospital stay (P = 0.07 were not statistically different between the groups. Conclusion: Using topical TXA via endoscopic procedures may be effective in cases of GI bleedings caused by active bleeding ulcers. In order to establish this therapeutic effect, a large number of clinical studies are needed.

  17. Dithiol-PEG-PDLLA micelles: preparation and evaluation as potential topical ocular delivery vehicle.

    Science.gov (United States)

    Yang, Jian; Yan, Jing; Zhou, Zhihan; Amsden, Brian G

    2014-04-14

    Thiol-modified nanoparticles have potential applications in mucoadhesive drug delivery and have been examined in this regard for topical ocular delivery. In this paper we provide a simple method for the synthesis of a dithiol terminated amphiphilic diblock copolymer. Bidentate dithiol-poly(ethylene glycol)-poly(d,l-lactide) (SH2-PEG-PDLLA) was synthesized and micelles with dithiol-containing coronas were prepared from this block copolymer via the emulsion method. In vitro release studies indicated that the presence of the thiol groups at the surface did not affect the rate of release of dexamethasone, used as a representative ocular drug. The micelles also showed low cytotoxicity to human corneal epithelial cells (HCEC) and murine fibroblast cells (3T3 cells). A hydrophobic red fluorophore, Nile red, was loaded into the core of micelles and confocal microscopy was used to study HCEC uptake and retention of the micelles. The micelles were rapidly endocytosed by the HCEC, with intracellular micelle levels remaining unchanged with incubation times from 5 to 120 min. Interestingly, Nile red was eliminated significantly more slowly from HCECs treated with the thiolated micelles. These results suggest that these dithiolated micelles may be effective for topical ocular drug delivery. PMID:24611557

  18. Suzhou Cartoon Industry Development Present Situation and Promotion Strategy%宿州动漫产业发展的现实状况及推进策略

    Institute of Scientific and Technical Information of China (English)

    魏三强; 张万礼

    2012-01-01

    In recent years, Suzhou cartoon industry has its preliminary development, but it is facing many practical problems: the number of animation company is small, the animation specialty talents are in shortage, the lack of capital is the bottleneck restriction of animation company and its market operation mechanism is not well organized, etc. The following effective strategies should be taken to promote the development of Suzhou cartoon industry: increase supporting strength, improve the cartoon industry policy system, complete the anime talent structure, cultivate high skilled professionals, open investment and financing channels in animation company, and raising animation industry fund in various ways, take Suzhou local characteristic cultures as the theme, energetically develop original cartoon creation, drive the green GDP comprehensively. development of cartoon industry chain, promote Suzhou%近几年宿州动漫产业虽有了初步的发展,但正面:溢着许多现实的问题:动爱公司数量较少、动漫专业人才匮乏、资金短缺瓶颈制约、市场运营机制不健全等。推动宿州动漫产业的发展应采取有效的策略:加炙-帑扶力度,健全动漫产业政策体系:完善动漫人才结构,培养高端技能型人才;畅通投融资渠道,多方面筹集动漫产业发展资金;以宿州众多的地方特色文化为题材发展动漫原创,蒂动动漫产业链的发展,全面提升宿州的绿色GDP。

  19. Cartooning History: Canada's Stories in Graphic Novels

    Science.gov (United States)

    King, Alyson E.

    2012-01-01

    In recent years, historical events, issues, and characters have been portrayed in an increasing number of non-fiction graphic texts. Similar to comics and graphic novels, graphic texts are defined as fully developed, non-fiction narratives told through panels of sequential art. Such non-fiction graphic texts are being used to teach history in…

  20. The political cartoon in the libertarian journal A Plebe (1947-1949

    Directory of Open Access Journals (Sweden)

    Zélia Lopes Silva

    2013-06-01

    Full Text Available This article discusses the meanings of imagistic representations (drawings, cartoons published in A Plebe (The Plebs, from May 1947 to May 1949, the last period of the Edgard Leuenroth’s headship. Created in 1917, the newspaper, supported by libertarian principles, set up as a public sphere suited for the proletarian world because of discussing the problems that workers were facing in their daily lives. The paper printed whipping criticisms against the country's elites and fought, without respite, the capitalist system – qualified as parasitic, violent and expropriator –, supported by mystifying and equally violent enactments from its religious arm, expressed in the actions of the Catholic Church and whose struggle against was also systematic.

  1. Comprehensive evaluation of carboxylated nanodiamond as a topical drug delivery system

    Science.gov (United States)

    Lim, Dae Gon; Kim, Ki Hyun; Kang, Eunah; Lim, Sun Hee; Ricci, Jeremy; Sung, Si Kwon; Kwon, Myoung Taek; Jeong, Seong Hoon

    2016-01-01

    The best strategy in the development of topical drug delivery systems may be to facilitate the permeation of drugs without any harmful effects, while staying on the skin surface and maintaining stability of the system. Nanodiamonds (NDs) play a key role with their excellent physicochemical properties, including high biocompatibility, physical adsorption, reactive oxygen species (ROS) scavenging capability, and photostabilizing activity. Z-average sizes of carboxylated ND (ND–COOH) agglutinate decreased significantly as the pH increased. Fluorescein-conjugated ND was observed only on the stratum corneum, and no sample diffused into the dermal layer even after 48 hours. Moreover, ND–COOH and ND–COOH/eugenol complex did not show significant toxic effects on murine macrophage cells. ND improved in vitro skin permeation >50% acting as a “drug reservoir” to maintain a high drug concentration in the donor chamber, which was supported by quartz crystal microbalance results. Moreover, ND–COOH could adsorb a drug amount equivalent to 80% of its own weight. A photostability study showed that ND–COOH increased the photostability ~47% with regard to rate constant of the eugenol itself. A significant decrease in ROS was observed in the ND–COOH and ND–COOH/eugenol complex compared with the negative control during intracellular ROS assay. Moreover, ROS and cupric reducing antioxidant capacity evaluation showed that ND–COOH had synergistic effects of antioxidation with eugenol. Therefore, ND–COOH could be used as an excellent topical drug delivery system with improved permeability, higher stability, and minimized safety issue. PMID:27307736

  2. Assessment of topical versus oral ivermectin as a treatment for head lice.

    Science.gov (United States)

    Ahmad, Hesham M; Abdel-Azim, Eman S; Abdel-Aziz, Rasha T

    2014-01-01

    Many medications are available for treatment of pediculosis capitis including ivermectin. Our aim is to compare the efficacy and safety of topical versus oral ivermectin in treatment of pediculosis capitis. Sixty-two patients with proved head lice infestation were included and divided into group I (31 patients; received single topical application of 1% ivermectin) and group II (31 patients; received single dose of oral ivermectin). Treatment was repeated after 1 week for nonresponders. At 1 week after treatment, the eradication rates and improvement of pruritus were significantly higher among patients who received topical than oral ivermectin. When a second treatment, topical or oral, was given to nonresponders, the cure rates of infestation and pruritus was 100% and 97% among patients treated with topical and oral ivermectin, respectively with no significant difference between the two groups. This study suggests that both topical and oral ivermectin demonstrate high efficacy and tolerability in treatment of pediculosis capitis. However, a single treatment with topical ivermectin provides significantly higher cure of infestation and faster relief of pruritus than oral ivermectin. In addition, whether topical or oral ivermectin is used to treat head lice, a second dose is required in some cases to ensure complete eradication.

  3. Gaining trust as well as respect in communicating to motivated audiences about science topics.

    Science.gov (United States)

    Fiske, Susan T; Dupree, Cydney

    2014-09-16

    Expertise is a prerequisite for communicator credibility, entailing the knowledge and ability to be accurate. Trust also is essential to communicator credibility. Audiences view trustworthiness as the motivation to be truthful. Identifying whom to trust follows systematic principles. People decide quickly another's apparent intent: Who is friend or foe, on their side or not, or a cooperator or competitor. Those seemingly on their side are deemed warm (friendly, trustworthy). People then decide whether the other is competent to enact those intents. Perception of scientists, like other social perceptions, involves inferring both their apparent intent (warmth) and capability (competence). To illustrate, we polled adults online about typical American jobs, rated as American society views them, on warmth and competence dimensions, as well as relevant emotions. Ambivalently perceived high-competence but low-warmth, "envied" professions included lawyers, chief executive officers, engineers, accountants, scientists, and researchers. Being seen as competent but cold might not seem problematic until one recalls that communicator credibility requires not just status and expertise but also trustworthiness (warmth). Other research indicates the risk from being enviable. Turning to a case study of scientific communication, another online sample of adults described public attitudes toward climate scientists specifically. Although distrust is low, the apparent motive to gain research money is distrusted. The literature on climate science communicators agrees that the public trusts impartiality, not persuasive agendas. Overall, communicator credibility needs to address both expertise and trustworthiness. Scientists have earned audiences' respect, but not necessarily their trust. Discussing, teaching, and sharing information can earn trust to show scientists' trustworthy intentions.

  4. A Cultural Interpretation on Cartoon Movies%卡通电影的文化阐释

    Institute of Scientific and Technical Information of China (English)

    程瑜瑜

    2014-01-01

    As a very special artistic form and an alternative means of cultural narration , Cartoon movies reflecting the world of reality through a series of pictures is usually defined as a pop culture .Its unique insight into artistry , musicality and literariness of different arrangements has won the popularity among large audiences .Various cartoon movies seem to have established a kind of ar-tistic Utopia, presenting the carnival spirit , which have adored colorful nationality and try to integrate them into universality , simul-taneously deconstructed the grand narratives with sharp modernity and post -modernism style .%被界定为通俗文化的动画电影是以一系列图片组合而成的对真实情境世界进行映射的一种特殊的艺术形式,是一种另类的文化叙事方式,它以直观而开放的方式表达出不同层次和水平的艺术性、音乐性及文学性,深受大众的喜爱。形形色色的卡通电影建构了艺术的乌托邦,展现着狂欢节的精神,以开放的文化维度接纳民族性并融入世界性,并以消解宏大叙事的方式讲述故事,呈现了卡通电影的现代性与后现代风格。

  5. Iconography and Politics in South Africa: the representation of Nelson Mandela, Thabo Mbeki and Jacob Zuma in cartoons of Zapiro

    Directory of Open Access Journals (Sweden)

    Renata de Paula dos Santos

    2014-12-01

    Full Text Available Mandela’s victory in the 1994 elections in South Africa is a reference point for South African history and represented the transition from apartheid to multiracial democracy. Since then Nelson Mandela (1994-1999, Thabo Mbeki (1999-2008 and Jacob Zuma (2009 - current, occupied the post of president of the country and led, each in its own way, the new direction of the country. During the nearly twenty years of multiracial democracy, one in particular cartoonist, Jonathan Shapiro, popularly known by the pseudonym Zapiro, portrayed the everyday life of this story. In this sense, the objective of this research is to analyze how Zapiro portrayed the political and social aspects, as well as the psychological characteristics of each of the three postapartheid presidents and which social representations are formed from their cartoon production. The choice of Zapiro explained by openly declared his opposition to apartheid and also for being the best known outside South African cartoonist. We elected to cartoon as an object of study because it is an iconographic object constituted by communicative humor, which adds to its constitution arguments transgression of the established order, enabling an analysis of South African history through a critical bias. As methods for the development of the work, we decided to gather historical research, the literature search and analysis of cartooon speech. Among the theoretical frameworks stand out Magnoli (1998, 2009, Jonge (1991 and Carlin (2009 in the South African question; reflections about social representations, we resort to Moscovici (2011 and Jodelet (1993, in the field the cartoon and humor, the references are Miani (2005; 2012, Romualdo (2000 and Eco (1989. With the completion of the analysis, we observed that Zapiro acts in different ways in the construction of the representation of each of the presidents in question and that the cartoonist presents Mandela as a competent leader marked by heroism and

  6. Adrenal insufficiency as a result of long-term misuse of topical corticosteroids.

    Science.gov (United States)

    Böckle, Barbara C; Jara, David; Nindl, Werner; Aberer, Werner; Sepp, Norbert T

    2014-01-01

    The treatment of chronic inflammatory skin disease is associated with the use of topical corticosteroids. Their efficacy, tolerability and adverse effects depend on several factors, specifically potency, type of preparation, extemporaneous dilutions, quantity used, magnitude of the treated body surface, frequency of application, location, patient age, method of application and condition of the skin barrier. We report on two men suffering from chronic inflammatory skin disease, who presented with fatigue and cushingoid appearance after prolonged self-application of potent corticosteroids. Impairment of the skin barrier due to their underlying skin disease, frequent self-application of topical steroids and repeated application of the entire body led to extensive absorption of these substances, eventually culminating in the suppression of the pituitary-hypothalamic-adrenal axis. In conclusion, topical corticosteroids are effective and well-established therapeutic modalities. However, inappropriate use of topical corticosteroids can cause side effects. PMID:24751677

  7. Topical issues of functioning a region as a social-economic system

    Directory of Open Access Journals (Sweden)

    Roman Andreyevich Timofeyev

    2015-09-01

    Full Text Available Objective to identify the topical issues of forming a region as a socialeconomic system. Methods systematic approach based on general scientific methods of empirical and theoretical research such as observation and comparison analysis and synthesis induction and deduction as well as comparativehistorical method statistical methods macroeconomic analysis. Results the major issues of applying a systematic approach to the analysis of the region as a socioeconomic system were explored and analyzed. The authors proved the most important features of the system considered different points of view on the content of the region as a system category analyzed the basic paradigm of the region functioning identified specific properties inherent to the region as a system conducted analysis of the modern Russian and foreign literature which showed that at present there is no consensus about the structural content of the region as an economic system at mesolevel suggested the authorsrsquo definition of the region category conclusions were made about the applicability of systematic approach to analyzing a region as a socioeconomic system. Scientific novelty the trends and problems of the region formation as an economic system were specifiedin the form of components of a single social and economic system the conceptual scheme for the region development as a socioeconomic system at mesolevel was proposed the author39s definition of the regionwas given. The suggested conceptual framework focuses on regional subsystems each of which is characterized by resources capacity the effective use of which is intended to ensure the sustainable and competitive territory development while increasing the quality of life of the population under federalism and globalization. Practical significance conclusions and suggestions can be used by public authorities in the strategic policy development for the effective management of the Russian regions. nbsp

  8. The Effects of Concept Cartoons on Eliminating Students’ Misconceptions: Greenhouse Effect and Global Warming

    Directory of Open Access Journals (Sweden)

    Lale Cerrah Ozsevgeç

    2012-10-01

    Full Text Available The aim of the study is to examine the effects of concept cartoons on eliminating students’ misconceptions about the global warming and greenhouse effect. The sample of the study is consisted of 17 students from the 7 grade of Rize Çay Primary School. Simple experimental study design was used in the study. Test and semi-structured interview were used to collect the data. The results of the study showed that the students had misconceptions about global warming and greenhouse effect. The teaching process comprising concept cartoons treated most of these misconceptions. Students indicated that the teaching process was enjoyable and it eased the students’ remembering of the given knowledge. Based on the results, it was suggested that the teachers should be informed about the usage of concept cartoon in the classroom and combination of different teaching methods which is supported by concept cartoon may be more useful for different science subjects.

  9. Can a Ban on Foreign Cartoons Boost the Local Animation Industry?

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Most children have become so addicted to TV, because there is precious little else they do for fun. Part of that enjoyment, in China, is the many cartoon programs available for young viewers, a large number of which are foreign productions. But that's all about to change. Foreign cartoons can no longer be screened during prime time viewing. Now millions of upset parents and children are questioning a new regulation

  10. Ferulic Acid-Based Polymers with Glycol Functionality as a Versatile Platform for Topical Applications.

    Science.gov (United States)

    Ouimet, Michelle A; Faig, Jonathan J; Yu, Weiling; Uhrich, Kathryn E

    2015-09-14

    Ferulic acid-based polymers with aliphatic linkages have been previously synthesized via solution polymerization methods, yet they feature relatively slow ferulic acid release rates (∼11 months to 100% completion). To achieve a more rapid release rate as required in skin care formulations, ferulic acid-based polymers with ethylene glycol linkers were prepared to increase hydrophilicity and, in turn, increase ferulic acid release rates. The polymers were characterized using nuclear magnetic resonance and Fourier transform infrared spectroscopies to confirm chemical composition. The molecular weights, thermal properties (e.g., glass transition temperature), and contact angles were also obtained and the polymers compared. Polymer glass transition temperature was observed to decrease with increasing linker molecule length, whereas increasing oxygen content decreased polymer contact angle. The polymers' chemical structures and physical properties were shown to influence ferulic acid release rates and antioxidant activity. In all polymers, ferulic acid release was achieved with no bioactive decomposition. These polymers demonstrate the ability to strategically release ferulic acid at rates and concentrations relevant for topical applications such as skin care products. PMID:26258440

  11. Representation of the cartoon controversy on the U.S. newspapers

    Directory of Open Access Journals (Sweden)

    Yusuf Yüksel

    2015-02-01

    Full Text Available Cartoon Crisis composed one of the most comprehensive international security problems of the last decade. A Danish newspaper, Jyllands-Posten, published 12 cartoons to satirize Prophet Mohammed in September 2005 which resulted in boycotts, anger and violent protest and thus a global conflict. The dispute over the cartoons has brought out the questions about the relations between the Islamic World and the West, the role of media on those relations, the limits of freedom of speech and right to protests and violence. This study aimed to find out how the cartoon controversy was represented in the US news media and the difference between newspapers depending on the rate of Muslim population in their circulation area.  A content analysis of Detroit Free Press, Herald News, Omaha World-News and Wyoming Tribune-Eagle newspapers are used to test the hypothesis about the publication of the cartoons and reaction of the Muslims to this issue. The findings suggest that the newspapers published in Muslim diverse communities are likely to draw more attention to the controversy. However, the difference is not significant. All of the four newspapers present negative views not only about the publication of the cartoons but also the reaction of the Muslims.

  12. Neural responses to cartoon facial attractiveness: An event-related potential study.

    Science.gov (United States)

    Lu, Yingjun; Wang, Jingmei; Wang, Ling; Wang, Junli; Qin, Jinliang

    2014-06-01

    Animation creates a vivid, virtual world and expands the scope of human imagination. In this study, we investigated the time-courses of brain responses related to the evaluation of the attractiveness of cartoon faces using the event-related potential (ERP) technique. The results demonstrated that N170 amplitude was higher for attractive than for unattractive cartoon faces in males, while the opposite was found in females. Facial attractiveness notably modulated the late positive component (LPC), which might reflect the task-related process of aesthetic appraisal of beauty. The mean LPC amplitude in males was significantly higher for attractive cartoon faces than for unattractive faces, while the LPC amplitude in females did not significantly differ between attractive and unattractive cartoon faces. Moreover, the paint mode (computer graphics, gouache, and stick figure) modulated the early encoding of facial structures and the late evaluative process. The early modulation effect by paint mode may be related to the spatial frequency of the pictures. The processing speed and intensity in females were both higher than those in males. In conclusion, our study, for the first time, reported ERP modulation based on the assessment of cartoon facial attractiveness, suggesting the facilitated selection of attractiveness information at the early stage, and that the attentional enhancement of attractive faces at the late stage only exists in males. This suggests that men's brains are hard-wired to be sensitive to facial beauty, even in cartoons.

  13. Working Capital Management as a routine: An action based access to the topic

    Directory of Open Access Journals (Sweden)

    Petra Kroflin

    2015-10-01

    Full Text Available In times of unstable capital markets on the one side and historically low interests on the other, working capital management must be discussed from different perspectives. Limited sources of liquidity, and the high refinancing risk of lending companies, make the reduction of current assets and liabilities an even more important management task than before. On the other hand, low interest rates raise the need for defining the optimum level for working capital. Little research and empirical evidence exists when it comes to lifting working capital targets to create value. The objective of the present paper is to give evidence on whether German companies adapt their behavior in terms of handling working capital in the actual economic environment and to describe which practices have been established to perform this adaptation. The given analysis is based on a qualitative study. The data used have been gathered in 2014 and 2015 during semi structured interviews with CFOs or financial executives of 15 German and Austrian industrial firms. Our study suggests that adaptation is realized rather by moderating management attention and focus to the topic of capital cost but not by adjusting the financial targets themselves. This is because working capital reduction as become a management routine.

  14. Topical treatment with propranolol gel as a supplement to the existing treatment of hemangiomas

    Institute of Scientific and Technical Information of China (English)

    Markus Schneider; Andreas Reimer; Hansjoerg Cremer; Peter Ruef

    2014-01-01

    Background: Systemic treatment with propranolol is proven to be effective for patients with hemangiomas with less side-effect. We used a propranolol gel for topical use on hemangiomas. Methods: In this retrospective study, we analyzed 148 patients who had been treated topically with propranolol gel for 12 weeks. We analyzed the data of patients and clinically gave each hemangioma a "hemangioma score" to determine the treatment success. Results: In 147 of the 148 patients, strong signs of resolution under treatment included lightening, paling, and less vascularization. The hemangioma score showed a signifi cant decrease during the treatment. Relevant serum levels of propranolol were not found. Adverse effects were rare and not related to propranolol. Conclusion: Topical treatment with propranolol gel is suitable for specific hemangiomas in addition to cryotherapy and systemic treatment with propranolol.

  15. Topical pimecrolimus as a new optional treatment in cutaneous sarcoidosis of lichenoid type.

    Science.gov (United States)

    Tammaro, Antonella; Abruzzese, Claudia; Narcisi, Alessandra; Cortesi, Giorgia; Parisella, Francesca Romana; Di Russo, Pier Paolo; De Marco, Gabriella; Persechino, Severino

    2014-01-01

    We report the case of cutaneous sarcoidosis of lichenoid type successfully treated with pimecrolimus. For the first time in the literature, we propose the use of this topical calcineurin inhibitor for the treatment of the cases refractory to common therapy regimens. PMID:24826355

  16. Topical Pimecrolimus as a New Optional Treatment in Cutaneous Sarcoidosis of Lichenoid Type

    Directory of Open Access Journals (Sweden)

    Antonella Tammaro

    2014-01-01

    Full Text Available We report the case of cutaneous sarcoidosis of lichenoid type successfully treated with pimecrolimus. For the first time in the literature, we propose the use of this topical calcineurin inhibitor for the treatment of the cases refractory to common therapy regimens.

  17. Topical Pimecrolimus as a New Optional Treatment in Cutaneous Sarcoidosis of Lichenoid Type

    OpenAIRE

    Antonella Tammaro; Claudia Abruzzese; Alessandra Narcisi; Giorgia Cortesi; Francesca Romana Parisella; Pier Paolo Di Russo; Gabriella De Marco; Severino Persechino

    2014-01-01

    We report the case of cutaneous sarcoidosis of lichenoid type successfully treated with pimecrolimus. For the first time in the literature, we propose the use of this topical calcineurin inhibitor for the treatment of the cases refractory to common therapy regimens.

  18. Oral Language Development as a Precursor to Literacy. ERIC Topical Bibliography and Commentary.

    Science.gov (United States)

    Smith, Carl B., Ed.

    Research suggests that oral language development is directly related to literacy, and is crucial for success in learning to be literate. This topical bibliography and commentary discusses language acquisition theories, components of language, phonology in literacy, and a first-grade classroom study that explored "literate talk" in the classroom…

  19. Experiences of Teaching the Heat Energy Topic in English as a Second Language

    Science.gov (United States)

    Halim, Lilia; Dahlan, Fathiyah; Treagust, David F.; Chandrasegaran, A. L.

    2012-01-01

    In view of the current debate in Malaysia about the teaching of science and mathematics in English, a qualitative study was undertaken involving a purposeful sampling of three non-physics teachers to ascertain how well equipped they were with the necessary pedagogical content knowledge relating to the teaching of the topic of "heat energy" in the…

  20. Reclaiming Race as a Topic of the U.S. Biology Textbook Curriculum

    Science.gov (United States)

    Donovan, Brian M.

    2015-01-01

    Even though human racial difference has been a longstanding topic of the school biology curriculum, there is little evidence that contemporary biology textbooks challenge stereotypical racial beliefs that are based in biological thinking. Rather, the modern biology curriculum may be a place where such beliefs about race are perpetuated…

  1. Evaluation of Topical Preparations Containing Curcuma, Acacia and Lupinus Extracts as an Anti-inflammatory Drugs

    OpenAIRE

    M M Hamzah

    2011-01-01

    Summary: This work was suggested on the basis of presence of curcuminoids in curcuma and the presence of flavonoidal constituent in acacia and lupinus. The aim of this study was to study their possible anti-inflammatory effect by separately formulation of the three extracts in a suitable gel formula for topical administration and comparison of the prepared gels with a standard gel in the market (diclosal Emulgel) by using the carrageenan induced paw edema model in albino rats. The extracts we...

  2. The human heart and the circulatory system as an interesting interdisciplinary topic in lessons of physics and biology

    Science.gov (United States)

    Volná, M.; Látal, F.; Kubínek, R.; Richterek, L.

    2014-01-01

    Many topics which are closely related can be found in the national curriculum of the Czech Republic for physics and biology. One of them is the heart and the circulatory system in the human body. This topic was examined cross curriculum, a teaching module was created and the topic was chosen for our research. The task was to determine if the students of bachelor study are aware of connections between physics and biology within this topic and whether we can help them effectively to describe the corresponding physics phenomena in the human body connected, for example, with a heart attack or with the measurement of blood pressure. In this paper, the heart and the circulatory system are presented as suitable topics for an interdisciplinary teaching module which includes both theoretical and experimental parts. The module was evaluated by a group of first-year undergraduate students of physics at the Faculty of Science, Palacký University. The acquired knowledge was compared with another control group through a test. The highest efficiency of the module was evaluated on the basis of questions that covered the calculation problems.

  3. "Chinese Children Rise Up!": Representations of Children in the Work of the Cartoon Propaganda Corps during the Second Sino-Japanese War

    Directory of Open Access Journals (Sweden)

    Laura Pozzi

    2014-12-01

    Full Text Available During the War of Resistance against Japan (1937–1945, children were a major subject of propaganda images. Children had become significant figures in China when May Fourth intellectuals, influenced by evolutionary thinking, deemed “the child” as a central figure for the modernization of the country. Consequently, during the war, cartoonists employed already-established representations of children for propagandistic purposes. By analyzing images published by members of the Cartoon Propaganda Corps in the wartime magazine Resistance Cartoons, this article shows how portrayals of children fulfilled symbolic as well as normative functions. These images provide us with information about the symbolic power of representations of children, and about authorities’ expectations of China’s youngest citizens. However, cartoonists also created images undermining the heroic rhetoric often attached to representations of children, especially after the dismissal of the Cartoon Propaganda Corps in 1940. This was the case with cartoonist Zhang Leping’s (1910–1992 sketches of “Zhuji after the Devastation,” which revealed the discrepancies between propagandistic representations and children’s everyday life in wartime China.

  4. Fluorouracil Topical

    Science.gov (United States)

    ... topical solution are used to treat actinic or solar keratoses (scaly or crusted lesions [skin areas] caused by years of too much exposure to sunlight). Fluorouracil cream and topical solution are also used to treat ...

  5. Bimatoprost Topical

    Science.gov (United States)

    Topical bimatoprost is used to treat hypotrichosis (less than the normal amount of hair) of the eyelashes by promoting ... growth of longer, thicker, and darker lashes. Topical bimatoprost is in a class of medications called prostaglandin ...

  6. Testosterone Topical

    Science.gov (United States)

    ... in which the body does not produce enough natural testosterone). Testosterone is used only for men with ... topical may control your symptoms but will not cure your condition. Continue to use testosterone topical even ...

  7. Cartoon Style 3D Game Scene Design Technology%卡通风格3D游戏场景设计制作技术

    Institute of Scientific and Technical Information of China (English)

    曹瑜; 郭立萍; 杜红燕; 王文静

    2015-01-01

    游戏场景的设计决定了整个游戏的氛围和视觉效果.以中国古村落游戏场景为例,结合游戏场景设计与制作过程中用到的3DS Max建模工具、Photoshop贴图绘制工具与Unity场景集成及自然环境模拟工具,介绍了3D卡通场景建模技术、卡通模型贴图技术、游戏场景集成技术、自然环境模拟技术,给出了一个卡通风格游戏场景高效的制作方案.%Game scene design decisions the entire game atmosphere and visual effects.As an example in Chinese ancient village,combined with game scene design and production tools such as: 3ds Max modeling tools,Photoshop textures drawing tools and Unity scene integration and the natural environment simulation tools,this paper introduces 3D cartoon scene modeling technology,Cartoon model mapping technology,game scene integration technology,natural environment simulation technology.This paper presents an efficient production program for the cartoon style game scene.

  8. 弗洛伊德“人格结构理论”在电影中的成功运用——以动画影片《麦兜响当当》为例%The Successful Application of Sigmund Freud' s "Personality Structure Theory" in Movies--Take Cartoon Movie "McDull Kung Fu Kindergarten " as an Example

    Institute of Scientific and Technical Information of China (English)

    汪书春

    2011-01-01

    As an important part of Sigmund Freud's Analytical Spirit Doctrine, "Personality Structure Theory" is all around us. It is illustrated that how this theory is applied in contemporary movies successfully through taking cartoon movie " McDull Kung Fu Kindergarten " as an example. It is pointed out that the three figures of the movies exactly stand for id, ego and superego of personality structure in one person.%作为弗洛伊德精神分析学重要组成部分的“人格结构理论”无处不在。以动画影片《麦兜响当当》为例,指明当代电影中如何成功运用这一理论;从个体精神境界的本我(id)、自我(ego)和超我(superego)三个层次,分别探讨了影片中麦兜、麦太和道长三个人物形象。

  9. EXCOL: an EXtract-and-COmplete layering approach to cartoon animation reusing.

    Science.gov (United States)

    Zhang, Lei; Huang, Hua; Fu, Hongbo

    2012-07-01

    We introduce the EXtract-and-COmplete Layering method (EXCOL)--a novel cartoon animation processing technique to convert a traditional animated cartoon video into multiple semantically meaningful layers. Our technique is inspired by vision-based layering techniques but focuses on shape cues in both the extraction and completion steps to reflect the unique characteristics of cartoon animation. For layer extraction, we define a novel similarity measure incorporating both shape and color of automatically segmented regions within individual frames and propagate a small set of user-specified layer labels among similar regions across frames. By clustering regions with the same labels, each frame is appropriately partitioned into different layers, with each layer containing semantically meaningful content. Then, a warping-based approach is used to fill missing parts caused by occlusion within the extracted layers to achieve a complete representation. EXCOL provides a flexible way to effectively reuse traditional cartoon animations with only a small amount of user interaction. It is demonstrated that our EXCOL method is effective and robust, and the layered representation benefits a variety of applications in cartoon animation processing.

  10. Mentalization of complex emotions in borderline personality disorder: The impact of parenting and exposure to trauma on the performance in a novel cartoon-based task.

    Science.gov (United States)

    Brüne, Martin; Walden, Sarah; Edel, Marc-Andreas; Dimaggio, Giancarlo

    2016-01-01

    Borderline personality disorder (BPD) is characterized by a range of interpersonal difficulties, which are, in part, related to adverse experiences during childhood. Unresponsive parenting and traumatization may cause functional impairment of mentalization, i.e. the ability to reflect upon own and others' mental states. However, the relationship of poor parenting, trauma and mentalization in BPD has not exhaustively been studied. Thirty patients diagnosed with BPD and 30 matched control subjects were asked to sequence a novel cartoon-based mentalization task involving complex emotions such as jealousy, shame, guilt etc. In addition, they were required to reason about cognitive and affective mental states of the cartoon characters. The quality of parental care was assessed using a self-report measure for recalled parental rearing style, and childhood trauma was measured in retrospect using the Childhood Trauma Questionnaire. Patients with BPD performed more poorly in all aspects of the cartoon task. Mentalizing skills, particularly relating to affective mental states, were uniquely associated with the quality of recalled parental care and childhood trauma. Together, the quality of parental care and the experience of childhood trauma negatively impact on mentalization in BPD, even in an experimental "offline" task.

  11. Garcinia gardneriana (Planchon & Triana) Zappi. (Clusiaceae) as a topical anti-inflammatory alternative for cutaneous inflammation.

    Science.gov (United States)

    Otuki, Michel F; Bernardi, Camila A; Prudente, Arthur S; Laskoski, Kerly; Gomig, Franciane; Horinouchi, Cintia D S; Guimarães, Claudio L; Ferreira, Juliano; Delle-Monache, Franco; Cechinel-Filho, Valdir; Cabrini, Daniela A

    2011-07-01

    Garcinia gardneriana is popularly used in skin disorders; therefore, this article investigated the effect of G. gardneriana extracts from leaves, bark and seeds and two isolated compounds in ear oedema and leucocytes migration caused by croton oil. The topical application of the extract of G. gardneriana leaves was able to reduce (70 ± 3%, and ID(50) 0.33 mg/ear) ear oedema, while the seeds (51 ± 5%) and the wood (60 ± 12%) extracts were less effective. In a time-course evaluation, the leaf extract (1 mg/ear) was effective when applied 2 hr before and until 3 hr after the stimulation, presenting a higher effectiveness when applied right after croton oil (83 ± 7% inhibition). In addition, the leaf extract was able to diminish the myeloperoxidase (MPO) activity in 64 ± 13%, which suggests the inhibition of leucocyte infiltration that was confirmed by histological analysis. Also, both biflavonoids isolated from the leaves of G. gardneriana, fukugetin (or morelloflavone) and 13-naringenin-II 8-eriodictyol (GB-2a), were able to reduce ear oedema, with ID(50) values of 0.18 (0.10-0.28) and 0.22 (0.15-0.31) mg/ear, respectively, besides the inhibition of MPO activity of 52 ± 6% and 64 ± 5%, respectively. Using the fluorescent probe 2',7'-dichlorodihydrofluorescein diacetate, the leaf extract, fukugetin and GB-2a topically applied to the ear treated with croton oil reduced 52 ± 15%, 63 ± 17% and 83 ± 4%, respectively, the production of reactive oxygen species of the skin. Thus, these results reveal the anti-inflammatory effect of G. gardneriana leaves for topical usage, and both biflavonoids are responsible for this effect. PMID:21362142

  12. The State and Modernity as Anthropological Topics: A Very Short Introduction

    OpenAIRE

    Marina Simić

    2016-01-01

    This paper aims to offer a brief introduction to anthropological studies of modernity and the state. I try to introduce some of the most important theoretical works in this field, built up in different ethnographic contexts ranging from Turkey to Latin America. I was trying to show some of the possibilities of the research of modernity and the state in anthropology emphasizing what anthropology can offer to wider debates on these topics. I argue that the ideas of modernity and the state are f...

  13. Severe hyperkalemia as a complication of timolol, a topically applied beta-adrenergic antagonist

    Energy Technology Data Exchange (ETDEWEB)

    Swenson, E.R.

    1986-06-01

    Severe hyperkalemia occurred in a patient with radiation pneumonitis and glaucoma shortly after beginning prednisone therapy. There was no evidence of renal failure, diabetes, acidosis, increased potassium intake, or significant tissue trauma. Medications having adverse effects on potassium metabolism were considered, and the patient's use of timolol maleate eyedrops was discontinued. His serum potassium level normalized despite continuation of the prednisone therapy. He became hyperkalemic on rechallenge with timolol and normokalemic following its withdrawal. This case indicates that the potential for beta-blocker-induced hyperkalemia exists even with topical appreciation.

  14. The Concept of the Interculture in Time: (Intercultural Topics in Textbooks of French as a Foreign Language

    Directory of Open Access Journals (Sweden)

    Meta Lah

    2012-12-01

    Full Text Available The article deals with the concept of interculturality as used in foreign language didactics. In accordance with the definition of interculturality given in the first part of the article, two categories are included in the analysis – two “levels” of culture, each of them bearing a different name in literature, namely high and popular culture. Various textbooks used for teaching French as a foreign language in Slovenia in both the past and present were chosen for the analysis of topics that cover a fairly long period of time – among them the textbooks by two Slovenian authors: Južnič (1938 and Grad (1954, as well as some generally-used French textbooks, such as Cours de langue et de civilisation françaises (1953, Le nouveau sans frontières (1988 and Nouveau rond point (2011. The article is based on the hypothesis that high culture is more likely to be present in the older textbooks, which are based on traditional methods, whereas in modern textbooks more popular, everyday topics can be found. It is also presumed that topics in modern textbooks are, compared to their more traditional counterparts, introduced in an intercultural manner which could encourage students to compare the culture of the foreign country with their own. Both hypotheses are partly confirmed. In Slovenian textbooks there are very few culture-based topics. On the other hand, they are present in all French textbooks, regardless of the methodology. It is true that Mauger introduces more high culture than the others and that the intercultural topics are presented only in the most recent textbook. In all the others, it is exclusively the culture of the target country that is introduced.

  15. Comparison of intravenous and topical lidocaine as a suppressant of coughing after bronchoscopy during general anesthesia.

    Science.gov (United States)

    Jakobsen, C J; Ahlburg, P; Holdgård, H O; Olsen, K H; Thomsen, A

    1991-04-01

    Twenty-four consecutive patients scheduled for fiberbronchoscopy were randomized to receive double-blind either intravenous (1.5 mg/kg) or laryngotracheal (3 mg/kg) lidocaine to evaluate the influence on post-bronchoscopic laryngospasm, pain in the throat and coughing. Plasma lidocaine concentrations were analyzed 5, 15, 30 and 60 min after administration. None of the patients demonstrated laryngospasm or pain in the throat during the first hour after bronchoscopy. Patients receiving topical lidocaine coughed significantly more than patients receiving intravenous lidocaine, with a median number of coughs of 20 compared to 4, during the first hour (P less than 0.01). The plasma lidocaine concentrations were significantly higher after intravenous than after topical administration (P less than 0.001). After intravenous administration the plasma lidocaine concentrations exceeded the accepted level for potential toxicity in five out of 11 patients, but none of the patients developed toxic symptoms and no side-effects were observed. PMID:2038931

  16. Topic and Textual Coherence

    Institute of Scientific and Technical Information of China (English)

    何明烈; 戢焕奇

    2008-01-01

    Based on the investigation of the origin and definition of topic as well as the classification of textual coherence, this paper ana-lyzes the function of topic to non-coherence, imphcit coherence and explicit coherence, and concludes that topic relevance is the primary cri-terion for textual coherence.

  17. A Case Report: Red Skin Syndrome- as the Rebound Effect of Using a Long Term Potent Topical Corticosteroid

    Directory of Open Access Journals (Sweden)

    Cristine D. Octaviani

    2014-06-01

    Full Text Available 31 years old male suffered from a rare skin disorder, diagnosed of red skin syndrome. Seven years ago, symptoms was begun with a light itching on skin area of body as well as face, and visited a general practitioner, diagnosed of light allergic rhinitis. He was prescribed oral corticosteroid, methyl prednisolone 4 mg b.i.d and very potent topical corticosteroid, clobetasol. The symptoms was significantly disappeared and being rebound after stopping the prescription. To maintain this rebound effect, for seven years in on-off unhealed conditions, he used topical cream corticosteroid, clobetasol, that fully masked this worst rebound condition. When application of the topical cream was stopped, rebound effect relapsed and even red skin syndrome became worse than before. After 20 months of being fully stopped from corticosteroid, the symptoms finally slowly reduced. He almost fully recovered and had a normal life until now December 2013. By this case, we can learn that this red skin syndrome, resulted from side effect of corticosteroid, will be stopped by fully stopping administering orally or topically, and this will take quite long time for skin to recover.

  18. The Role of Language and Gender in "The Transformers": An Analysis of Messages in Cartoons for Children.

    Science.gov (United States)

    Aitken, Joan E.

    New technologically-oriented cartoons have been developed in the 1980s, and they may influence the attitudes and behaviors of their viewing audiences, who are comprised primarily of male children. A study analyzed "The Transformers" television program (a new robotic cartoon consisting of a mixture of violence, technology, space travel, and…

  19. Teaching physics by means of cartoons: a qualitative study in secondary education

    Science.gov (United States)

    Perales-Palacios, F. Javier; Vílchez-González, José M.

    2002-09-01

    One of the characteristics of our times is the powerful socio-cultural influence of television. Formal education seems to be losing its attraction to youngsters in favour of TV: physics is no exception. We present here the first results of a working proposal aimed at coupling physics teaching with viewing cartoon programs. The study was carried out over two school years with a small number of participating students. It involved the individualized analysis of two cartoon programs by teachers and students with a focus on discriminating between `real' and `impossible' situations, a class discussion of the results, an attempt to give a physical explanation for what was observed, an in-depth debate about some of the previously identified phenomena, and a final interview with the students and their parents. Using TV cartoons was a clear incentive to the students and our results encourage us to develop the notion of TV `literacy' further.

  20. Spanish Darwinian iconography: Darwin and evolutionism portrayed in Spanish press cartoons.

    Science.gov (United States)

    Domínguez, Martí; Mateu, Anna

    2013-11-01

    The theory of evolution has played a major role in the press since it was put forward by Charles Darwin in 1859. Its key role in biology and human philosophy is reflected by its presence in press cartoons, sections where the image of social reality is depicted in a more direct and satirical light. Through cartoons, artists have used their ingenuity or wit to portray one of the most controversial scientific figures of the past two centuries. This study examines the views portrayed by Spanish cartoonists about Charles Darwin and evolutionary theory in 2009, the bicentenary of the naturalist's birth and the celebration of 150 years since the publication of On the Origin of Species. These cartoons show how the controversy between Darwinism and religion remain latent in the heart of Spanish society, and how the figure of Darwin has become one of the main icons of science.

  1. Nanoemulsion as a carrier to improve the topical anti-inflammatory activity of stem bark extract of Rapanea ferruginea

    Science.gov (United States)

    Dal Mas, Juarana; Zermiani, Tailyn; Thiesen, Liliani C; Silveira, Joana LM; da Silva, Kathryn ABS; de Souza, Márcia M; Malheiros, Angela; Bresolin, Tania MB; Lucinda-Silva, Ruth M

    2016-01-01

    The aim of this study was to develop nanoemulsion containing soft extract of stem bark of Rapanea ferruginea to improve the topical delivery and anti-inflammatory activity. The extract of R. ferruginea stem bark was incorporated into the oily phase of the nanoemulsion by the method of phase inversion at low energy. The developed nanoemulsion had an average droplet size of 47.88±8.20 nm and a polydispersibility index of 0.228. Uniformity of size, spherical shape of droplet, and absence of clusters were confirmed by transmission electronic microscopy. The zeta potential was −34.7±1.15 mV. The nanoemulsion showed a moderate degree of skin irritation in the agarose overlay assay in vitro. The content of the extract markers, myrsinoic acids A and B, was 54.10±0.08 and 53.03 μg/g in the formulation, respectively. The formulation demonstrated pseudoplastic and thixotropic rheological behavior. In vitro release of chemical markers was controlled by diffusion mechanism. An extract-loaded nanoemulsion showed a topical anti-inflammatory activity in a croton oil-induced edema ear model, with a decrease in tumor necrosis factor release and myeloperoxidase activity. The nanoemulsion was 160% more efficient than the conventional cream containing 0.13% of the extract. The nanoemulsion showed suitable properties as a carrier for topical use of R. ferruginea extract and the approach for improving the topical anti-inflammatory activity. PMID:27660442

  2. Topical Drugs for Pain Relief

    Directory of Open Access Journals (Sweden)

    Anjali Srinivasan

    2015-03-01

    Full Text Available Topical therapy helps patients with oral and perioral pain problems such as ulcers, burning mouth syndrome, temporomandibular disorders, neuromas, neuropathies and neuralgias. Topical drugs used in the field of dentistry are topical anaesthetics, topical analgesics, topical antibiotics and topical corticosteroids. It provides symptomatic/curative effect. Topical drugs are easy to apply, avoids hepatic first pass metabolism and more sites specific. But it can only be used for medications that require low plasma concentrations to achieve a therapeutic effect.

  3. Participation of women as authors and editors in journals concerned with mental retardation and related topics.

    Science.gov (United States)

    Porter, Cari L; Christian, LeeAnn; Poling, Alan

    2003-02-01

    The present survey determined women's participation in eight journals concerned with mental retardation and related topics. The number of female authors was recorded for all articles published in these journals from 1991 through 2000. The number of women on the editorial board each year, for each journal, also was tabulated. For all years and all journals, women were first authors of 41% of articles published. Women wrote 34% of single-author articles. Overall, 45% of all authors were women. Women constituted 34% of the editorial board members for the eight journals combined. In sum, these data suggest that women's contribution to the mental retardation literature decreases with the prestige of the activity. PMID:12597719

  4. Efficacy and Toxicity of Zinc Salts as Candidate Topical Microbicides against Vaginal Herpes Simplex Virus Type 2 Infection

    Science.gov (United States)

    Bourne, Nigel; Stegall, Rachael; Montano, Raquel; Meador, Michael; Stanberry, Lawrence R.; Milligan, Gregg N.

    2005-01-01

    Zinc salt solutions administered as topical microbicides provided significant protection against herpes simplex virus type 2 infection in a mouse vaginal challenge model. However, at the therapeutic concentration, the salt solutions caused sloughing of sheets of vaginal epithelial cells. These observations limit the utility of zinc salts as microbicides and suggest that the application of zinc solutions to mucosal surfaces has the potential to cause damage that might increase susceptibility to secondary infections at a later time. PMID:15728922

  5. 基于几何结构的2.5D卡通建模%2 . 5 D Cartoon Modeling Based on Geometric Structure

    Institute of Scientific and Technical Information of China (English)

    刘艳; 胡艳宏; 孙战利

    2015-01-01

    二维卡通制作技术大致分为计算机辅助2D卡通动画制作和利用3D建模技术渲染生成动画。将两者结合,提出一种2.5D卡通制作模型,通过几何结构的旋转进行纹理贴图,并构造卡通的旋转过程。在2D动画中,一个卡通形象本身隐含几何结构,将卡通形象定义为由只含一个典型几何结构卡通元素构成的卡通对象,利用典型几何结构二维投影变化规律,构建相应结构卡通元素的变形算法,分析长方体和球体卡通元素在转动时投影的变化规律,给出基于这些规律实现相应结构卡通元素伪3D转动效果的算法。通过长方体、球体、圆柱体进行旋转的实验结果证明了算法的有效性。%Technologies of 2 D cartoon animation can be roughly categorized into two types:one is computer-aided 2 D cartoon animation,and the other is rendering 3D models. These two both have their own pros and cons. So this paper proposes a way which combines both of them,that is 2. 5D cartoon modelling method which constructs the rotation of the cartoon by texture mapping. In 2D animation,a character has an implicit geometry structure. So in this paper,it defines a character as a cartoon object composed of only one typical geometry structure. This paper builds the deformation algorithm of corresponding structure through the two dimensional projection transformation of typical geometries. Detailed analysis of projection transformation patterns of rectangular and sphere are provided. Based on patterns founded,this paper provides algorithm for implementing pseudo-3D rotation effects for the corresponding carton elements, and gives the results of cuboid,sphere and cylinder to support the validity of the algorithm.

  6. 皖北地区动漫产业发展现状与推进策略%Northern Anhui Cartoon Industry Development Present Situation and Promotion Strategy

    Institute of Scientific and Technical Information of China (English)

    魏三强; 朱水源

    2012-01-01

      Under the“big development,great prosperity”background of our cultural industry,Northern Anhui cartoon industry has its preliminary development,but it is facing many practical problems:the number of animation company is small,the whole development level of animation company is low,the animation specialty talents are in shortage,the lack of capital is the bottleneck restriction of animation company and its market operation mechanism is not well organized,etc. The following effective strategies should be taken to promote the development of Northern Anhui cartoon industry:increase supporting strength,improve the cartoon industry policy system,complete the anime talent structure,cultivate high skilled professionals,open investment and financing channels in animation company,and raising animation industry fund in various ways,take Northern Anhui local characteristic cultures as the theme,energetically develop original cartoon creation,drive the development of cartoon industry chain, comprehensively promote Northern Anhui green GDP,strengthen the protection of intellectual property rights of animation products,ensure the sustainable development of animation industry.%  在我国文化产业“大发展、大繁荣”的时代背景下,皖北地区动漫产业虽有了初步的发展,但正面临着许多现实的问题:动漫公司数量较少、整体的发展水平偏低、动漫专业人才匮乏、资金短缺瓶颈制约、市场运营机制不健全等。推动皖北地区动漫产业的发展应采取有效的策略:加大帮扶力度,健全动漫产业政策体系;完善动漫人才结构,培养高端技能型专业人才;畅通投融资渠道,多方面筹集动漫产业发展资金;以皖北地区的地方特色文化为题材,大力发展动漫原创,带动动漫产业链发展,全面提升皖北地区的绿色GDP;加强动漫产品知识产权的保护,保障动漫产业的可持续发展。

  7. AI Topics

    OpenAIRE

    Buchanan, Bruce G; Glick, Jonathan

    2002-01-01

    The debut of the AI in the News column elsewhere in this issue of AI Magazine created a good opportunity to introduce the professional community to the AI Topics web site, home of the AI in the news virtual page. Although AI Topics is designed for the lay public, it serves a much larger audience.

  8. Misselling as a New Topic of Financial Education? A Didactic Analysis of Investment Advise after the Financial Crisis

    Directory of Open Access Journals (Sweden)

    Dirk Loerwald

    2010-07-01

    Full Text Available Personal financial investments are, as a matter of course, a topic of economic education because they are a life situation which is inherently economical. In contrast, faulty advising in banks which has become focussed upon due to the extent it has played a part in the recent financial crisis is mentioned neither in curricula nor in educational text books. Numerous private funds have been exposed as unprofitable investments. One reason for this problem is to be found in the marketing staff of the banks who did not invest their customer’s funds securely enough – and the customers did not notice it. What conclusions can be drawn from this for general financial education after the financial crisis? The economic education has failed to address the topic of “faulty advising in banks” as well. On the basis of categorical economic didactics the following contribution will analyse whether one has an exemplary case here upon which students can win generalized, transferable insights. In this context, the topic of personal financial investments will be classified in an efficient manner and the risk of opportunism in advising situations will be analysed with the help of the positive principal-agent theory. The results of this analysis of informational asymmetries within financial markets give direction to the development and revision of curricula in the didactics of economic education. With the following article a sustainable theoretical fundament will be created to underscore the obligatory inclusion of this topic in curricula as well as its realisation for target groups in school text books.

  9. Lavender-thymol as a new topical aromatherapy preparation for episiotomy: A randomised clinical trial.

    Science.gov (United States)

    Marzouk, T; Barakat, R; Ragab, A; Badria, F; Badawy, A

    2015-01-01

    The objective of this study was to evaluate the effectiveness of topical lavender-thymol in promoting episiotomy healing. This placebo-controlled, single-blinded, randomised clinical trial involved 60 primiparous women. REEDA score was used to evaluate the outcome of the trial. On the 7th post-partum day, women in Placebo-treated group had worse Redness, Edema, Ecchymosis, Discharge and Approximation (REEDA) score of 3.93 ± 3.65 compared with those in Lavender-thymol-treated group (2.03 ± 1.7) with significant difference (P = 0.013). Visual analogue Scale (VAS) score for pain at episiotomy in Lavender-thymol-treated group was 3.5 ± 1.9, whereas in Placebo-treated group it was 2.1 ± 2.2 (p = 0.011) for dyschezia, 3.8 ± 1.7 and 2.8 ± 1.6 in Placebo- and Lavender-thymol-treated women, respectively (p = 0.023). At 7th post-partum week, dyspareunia was more severe in Placebo-treated group compared with that in Lavender-thymol-treated group (5.3 ± 2.7 vs 2.7 ± 1.5 and p aromatherapy using lavender-thymol was highly effective, suitable and safe for episiotomy wound care with little or no expected side effects compared with that using placebo. PMID:25384116

  10. On Embody the Traditional Figure Painting Artistic Conception in Modern Chinese Wash Cartoon%现代水墨动画艺术形式中如何体现传统水墨人物画的意境

    Institute of Scientific and Technical Information of China (English)

    王乌云; 刘天婕; 曲猛

    2011-01-01

    China is the most distinct wash cartoon ethnic styles,the form of the cartoon creation meaningful.Wash cartoon visual language originates from our country in one thousand years history of the traditional water-ink paintings art form.The traditional aesthetic subject matter and the artistic conception,inevitable meeting as audio-visual art form in wash cartoon in,as the most characteristic of Chinese animation art form of ink painting animation it is traditional culture in China foreign animation art with the outcome of the combination of research,wash cartoon must study it and the traditional Chinese paternity.%中国水墨动画是最具有鲜明民族风格的动画片,其创作的形式充满诗情画意。水墨动画的视觉语言来源于我国千年来历史的传统水墨画艺术形式。传统的题材和审美意境,必然会作为视听的艺术形式介入水墨动画中来,作为最具本土特色的动画艺术形式的水墨动画它是我国传统文化同外来动画艺术相结合的产物,研究水墨动画必须研究它与中国传统的亲缘关系。

  11. Tert-butyl benzoquinone: mechanism of biofilm eradication and potential for use as a topical antibiofilm agent

    Science.gov (United States)

    Ooi, N.; Eady, E. A.; Cove, J. H.; O'Neill, A. J.

    2016-01-01

    Objectives Tert-butyl benzoquinone (TBBQ) is the oxidation product of tert-butyl hydroquinone (TBHQ), an antimicrobial food additive with >40 years of safe use. TBBQ displays potent activity against Staphylococcus aureus biofilms in vitro. Here, we report on studies to further explore the action of TBBQ on staphylococcal biofilms, and provide a preliminary preclinical assessment of its potential for use as a topical treatment for staphylococcal infections involving a biofilm component. Methods The antibacterial properties of TBBQ were assessed against staphylococci growing in planktonic culture and as biofilms in the Calgary Biofilm Device. Established assays were employed to measure the effects of TBBQ on biofilm structure and bacterial membranes, and to assess resistance potential. A living-skin equivalent was used to evaluate the effects of TBBQ on human skin. Results TBBQ eradicated biofilms of S. aureus and other staphylococcal species at concentrations ≤64 mg/L. In contrast to other redox-active agents exhibiting activity against biofilms, TBBQ did not cause substantial destructuring of the biofilm matrix; instead, the antibiofilm activity of the compound was attributed to its ability to kill slow- and non-growing cells via membrane perturbation. TBBQ acted synergistically with gentamicin, did not damage a living-skin equivalent following topical application and exhibited low resistance potential. Conclusions The ability of TBBQ to eradicate biofilms appears to result from its ability to kill bacteria regardless of growth state. Preliminary evaluation suggests that TBBQ represents a promising candidate for development as a topical antibiofilm agent. PMID:27121399

  12. Angiomatous reaction Kaposi-sarcoma-like as a side effect of topical corticosteroid therapy in lichen sclerosus of the penis.

    Science.gov (United States)

    Catricalà, Caterina; Marenda, Samantha; Muscardin, Luca Maria; Donati, Pietro; Lepri, Andrea; Eibenschutz, Laura

    2009-01-01

    Lichen sclerosus (LS) is a chronic inflammatory skin condition usually located in the anogenital area. Topical corticosteroid therapy is the first choice treatment which may arrest or delay the progression of the disorder. We report the case of a 74-year-old man presented with a 6-month history of nodular lesions localized on penis. The man had a previous history of genital lesions that had been diagnosed as LS and treated with long-term topical corticosteroid therapy. After 3 months of corticosteroid therapy, the patient observed the appearance of several nodular erythematous lesions on the penis with progressive disappearance of the clinical symptoms of LS. These purple to red asymptomatic angiomatoid nodules resembled the clinical features of Kaposi sarcoma. PMID:19580581

  13. Chemistry, Civil War (U.S.), Drawing & Cartooning, Gravity & Magnetism, Motion, Pets, Science Fiction & Fantasy Literature.

    Science.gov (United States)

    Web Feet, 2002

    2002-01-01

    This annotated subject guide to Web sites for grades K-8 focuses on chemistry, U.S. Civil War, drawing and cartooning, gravity and magnetism, motion, pets, science fiction and fantasy literature, and calendar connections for May observances. Specific grade levels are indicated for each annotation. (LRW)

  14. Using a Concept Cartoon© Method to Address Elementary School Students' Ideas about Natural Phenomena

    Science.gov (United States)

    Minárechová, Michaela

    2016-01-01

    This study investigated the identification and subsequent development or modification of students´ ideas about scientific phenomena by teaching by concept cartoons© method. We found out ideas of students of the fourth grade of primary school by conceptual tasks which were parts of quasi-experiment (pretest and posttest design). For triangulation…

  15. Does Cartoon Violence Beget Aggressive Behavior in Real Life? An Opposing View

    Science.gov (United States)

    Blumberg, Fran C.; Bierwirth, Kristen P.; Schwartz, Allison J.

    2008-01-01

    A commonly accepted belief is that the violence depicted in television programs, particularly cartoons, has a negative impact on young children's behavior. However, young children may be less inclined to emulate violent actions seen on television than currently thought. Research indicates that young children have limited comprehension of…

  16. Quirky quarks a cartoon guide to the fascinating realm of physics

    CERN Document Server

    Bahr, Benjamin; Piccolo, Rina

    2016-01-01

    Do you love quantum physics, cosmology, and the humor behind the popular television show The Big Bang Theory? Have you been on the lookout for a fun, non-technical explanation of the science behind things like time travel, wormholes, antimatter, and dark energy? You’ll find all of that, and more, inside this fact-filled, cartoon-packed book.

  17. The Effects of Computer-Aided Concept Cartoons and Outdoor Science Activities on Light Pollution

    Science.gov (United States)

    Aydin, Güliz

    2015-01-01

    The purpose of this study is to create an awareness of light pollution on seventh grade students via computer aided concept cartoon applications and outdoor science activities and to help them develop solutions; and to determine student opinions on the practices carried out. The study was carried out at a middle school in Mugla province of Aegean…

  18. A Summary of Information on the Behavior of the Yakima Fold Belt as a Structural Entity -- Topical Report

    Energy Technology Data Exchange (ETDEWEB)

    Last, George V.; Winsor, Kelsey; Unwin, Stephen D.

    2012-08-01

    This document is one in a series of topical reports compiled by the Pacific Northwest National Laboratory to summarize technical information on selected topics important to the performance of a probabilistic seismic hazard analysis (PSHA) of the Hanford Site. The purpose of this report is to summarize available data and analyses relevant to the Yakima Fold Belt (YFB) that may bear on the question of whether or not the YFB behaves as a single seismotectonic province in which activity along one fold structure is representative of behavior along all other fold structures. This topic has met with a fairly high level of contention in the expert community and has the potential to result in significant impacts on an evaluation of seismic hazard at the Hanford Site. This report defines the relevant alternative conceptual models relevant to this technical issue and the arguments and data that support those models. It provides a brief description of the technical issue and principal uncertainties; a general overview on the nature of the technical issue, along with alternative conceptual models, supporting arguments and information, and uncertainties; and finally, it suggests some possible approaches for reducing uncertainties regarding this issue.

  19. Clindamycin Topical

    Science.gov (United States)

    ... topical clindamycin.you should know that abrasive or medicated soaps and skin products that contain alcohol may ... in, tightly closed, and out of reach of children. Store it at room temperature and away from ...

  20. Estradiol Topical

    Science.gov (United States)

    ... Estradiol topical gel is also used to treat vaginal dryness, itching, and burning in women who are experiencing menopause. However, women whose only bothersome symptoms are vaginal burning, itching, and dryness may benefit more from a medication that is ...

  1. Tretinoin Topical

    Science.gov (United States)

    ... lotions, astringents, and perfumes); they can sting your skin, especially when you first use tretinoin.Do not use any other topical medications, especially benzoyl peroxide, salicylic acid (wart remover), and dandruff shampoos containing sulfur or ...

  2. Pictorial Metaphor in Selected Egyptian Newspapers Cartoons during the 25th of January 2011 Egyptian Revolution.

    Directory of Open Access Journals (Sweden)

    Ghada Abdel Aziz Ashmawi

    2014-03-01

    Full Text Available Metaphor is persuasive in having cognitive, emotional and aesthetic effect. It has been argued that any visual representation can be considered a metaphor if it represents a metaphoric thought. Chartris-Black’s Critical Metaphor Analysis and Forceville’s model of pictorial metaphor are both used to analyze the data under investigation. Chateris-Black’s Critical Metaphor Analysis is used based on the idea that the use of metaphors helps in conveying the underlying ideologies of the writers. Moreover, Forceville’s model of pictorial metaphor aims at investigating various types of pictorial metaphor in different genres. The political cartoons investigated in this study are drawn from three independent newspapers: Al Dastour, Al Masry Al Youm and Al Youm AL Sabea during the 25th of January 2011 Egyptian Revolution. This study aims at exploring how metaphors are expressed in the visual mode, more specifically in newspapers cartoons, tracing the use of pictorial metaphor in selected independent newspapers cartoons during the eighteen days of the 25th of January 2011 Egyptian revolution, and finally, identifying the cartoonists’ underlying ideological motivations and their attitudes to the revolution, which ultimately direct the audience’s ideology. The results of this study suggest that Chateris-Black’s Critical Metaphor Analysis can be applied not only on the textual level, but also on the semiotic and pictorial ones. In addition, metaphors are frequently used in political cartoons to evoke strong emotive effect and reinforce ideologies to achieve persuasion. Keywords: Pictorial Metaphor, Critical Metaphor Analysis, political cartoon

  3. [Topical therapy of rosacea].

    Science.gov (United States)

    Schöfer, H

    2013-07-01

    Metronidazole and azelaic acid are the only topical medications approved for rosacea. All other topical treatments for rosacea and its special forms are used off-label. Topical steroids are not indicated in rosacea, because of their side effects (induction of steroid rosacea, high risk of facial skin atrophy, and high risk of rebound after cessation of therapy). Topical as well as systemic steroids are allowed only as initial and short term therapy for acute forms of rosacea (e.g. rosacea fulminans). Papular and pustular rosacea is the major indication for topical therapy. Sebaceous gland and connective tissue hyperplasia in glandular-hypertrophic rosacea as well as erythema in erythematous rosacea do not respond well to topical measures. A new active substance, the alpha-2-adrenoreceptor agonist brimonidine, will be approved soon for the topical treatment of erythema in rosacea. All severe forms of rosacea should initially be treated with a combination of topical and systemic agents. After improvement of the clinical symptoms, topical treatment alone is usually adequate to maintain the control.

  4. Spotlight Topics

    Science.gov (United States)

    A Spotlight Topic consists of a set of two or more review articles focused on a specific subject in surface science. The topics are recommended by the Board of Editors. A topic may be chosen because it is particularly new or fast-breaking, thus deserving introduction to the general readership. Or, it may be because a topic is especially controversial or confusing, requiring clarification by experts. Each review will give a critical assessment rather than an encyclopedic report. While our editors always will insist on fairness and accuracy, any review which forwards an opinion is bound to be somewhat subjective. Therefore, it is the editors' wish that the set of reviews written by different authors on the same subject matter will provide a broad and balanced viewpoint. It is often the case that an author who is an expert in a technique or method may be especially enthusiastic or critical about this technique or method. A companion review in the set may provide a different viewpoint. We are hopeful that the reader, after studying these reviews and checking some of the key references, will obtain an informed opinion of the subject. We think the set of reviews in a spotlight area will considerably shorten the ``learning time'' that a nonexpert would otherwise need to become knowledgeable about a subject. In this issue, we feature a spotlight topic on oxide surfaces. The set contains an overview article by Jacques Jupille, and four articles written by G. Pacchioni, F. Cosandey and T. E. Madey, B. G. Daniels, R. Lindsay and G. Thornton, and C. Noguera respectively. Of these, the article by Pacchioni has already appeared in SRL 7, 277 (2000). The other three articles appear in this issue. A reader who wishes to suggest a spotlight topic or recommend authors to write such reviews should contact the Editor-in-Chief. We would like to hear from you.

  5. Evaluation of a polyherbal topical aerosol spray as a supportive therapy for clinical mastitis in dairy cows

    Directory of Open Access Journals (Sweden)

    Ramasamy Selvam

    2015-09-01

    Full Text Available The present study was designed to evaluate the polyherbal topical aerosol spray Wisprec and reg; Advanced (M/S. Natural Remedies Private Limited, India as a supportive therapy for clinical mastitis in dairy cows. A total of 41 dairy cows suffering from clinical mastitis were selected, and Wisprec and reg; Advanced was sprayed on mastitis affected quarters of udder two times a day along with a parenteral antibiotic till complete recovery. The rectal temperature, pain on palpation of udder, swelling of udder, consistency of milk, recovery period and product satisfaction score were assessed to evaluate the efficacy of Wisprec and reg; Spray. Topical application of Wisprec and reg; Advanced Spray have shown a significant improvement (p<0.001 in alleviation of rectal temperature, pain on palpation of udder and swelling of udder, and the consistency of milk was restored to normal after 3 to 4 days of treatment. The results demonstrate that the Wisprec and reg; Advanced spray could be considered as an alternative to non-steroidal anti-inflammatory drugs (NSAIDs as a supportive therapy for clinical mastitis of dairy cows. [J Adv Vet Anim Res 2015; 2(3.000: 285-290

  6. Balancing Constraints and the Sweet Spot as Coming Topics for Creativity Research

    DEFF Research Database (Denmark)

    Onarheim, Balder; Biskjaer, Michael Mose

    2015-01-01

    The aim of this chapter is the introduction of two new concepts, ‘balancing constraints’ and ‘the sweet spot of creativity’, as promising new paths for creativity research. This is motivated by the fact that creativity research shows a growing interest in the fundamental entwinement of constraints...... and creativity, with skillful and innovative handling of constraints seen as a prerequisite for apt creative performance. Based on a brief review of current disparate conceptualizations of constraints as both enablers and restrainers of creative activities, we begin by proposing the unifying concept ‘creativity...... constraints’ to help establish common terminological ground. Since the presence of constraints change over time, we suggest the term ‘constrainedness’ to articulate this total constraint intensity at a given time. This allows us to introduce our main contribution, the concept ‘the sweet spot’, to address...

  7. Balancing Constraints and the Sweet Spot as Coming Topics for Creativity Research

    DEFF Research Database (Denmark)

    Onarheim, Balder; Biskjaer, Michael Mose

    2016-01-01

    The aim of this chapter is the introduction of two new concepts, ‘balancing constraints’ and ‘the sweet spot of creativity’, as promising new paths for creativity research. This is motivated by the fact that creativity research shows a growing interest in the fundamental entwinement of constraints...... and creativity, with skillful and innovative handling of constraints seen as a prerequisite for apt creative performance. Based on a brief review of current disparate conceptualizations of constraints as both enablers and restrainers of creative activities, we begin by proposing the unifying concept ‘creativity...... constraints’ to help establish common terminological ground. Since the presence of constraints change over time, we suggest the term ‘constrainedness’ to articulate this total constraint intensity at a given time. This allows us to introduce our main contribution, the concept ‘the sweet spot’, to address...

  8. American National Identity in a Globalized World as a Topic in the Advanced EFL-Classroom

    Directory of Open Access Journals (Sweden)

    Peter Freese

    2008-06-01

    Full Text Available In order to make an issue as complex and controversial as that of ‘national identity’ teachable in the advanced EFL-classroom, it has to be reduced to exemplary aspects and illustrated with concrete examples. Therefore, I will suggest an appropriate ‘Course Opener,’ briefly survey the historical unfolding of the American identity concept in order to provide teachers with the necessary background knowledge, and then suggest two teaching units, the first of which traces some major developments by means of ‘classic’ texts, whereas the second deals with the crucial issue of whether a shared language is a prerequisite for a shared identity.

  9. New insights for an old topic: seagrasses as bioindicators of coastal trace element pollution

    OpenAIRE

    Richir, Jonathan; Lejeune, Pierre; Gobert, Sylvie

    2014-01-01

    The marine magnoliophyte Posidonia oceanica (L.) Delile has been widely used since the mid-70th to biomonitor the coastal pollution of the Mediterranean in Cr, Ni, Cu, Zn, Cd, Pb and/or Fe. In contrast, other trace elements (TEs) like As, V, Ag, Be, Al, Mn, Co, Se, Mo, Sn, Sb and Bi, many of them categorized as TEs of environmental emerging concern, have been subject to nearly no ecotoxicological survey with that species. It has been shown that the French Mediterranean littoral was submitted ...

  10. Advances in studies of phospholipids as carriers in skin topical application

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Objective:This article provides an overview of characteristics of phospholipids,the characteristics and influential factors of liposome and microemulsion as carriers for skin delivery of drugs,and the latest advances of the phospholipids carriers in transdermal delivery systems.The perspective is that phospholipids carriers may be capable of a wide range of applications in the transdermal defivery system.

  11. New lidocaine lozenge as topical anesthesia compared to lidocaine viscous oral solution before upper gastrointestinal endoscopy

    DEFF Research Database (Denmark)

    Mogensen, Stine; Treldal, Charlotte; Feldager, Erik;

    2012-01-01

    To evaluate the effect and acceptance of a new lidocaine lozenge compared with a lidocaine viscous oral solution as a pharyngeal anesthetic before upper gastrointestinal endoscopy (UGE), a diagnostic procedure commonly performed worldwide during which many patients experience severe discomfort mo...

  12. CARTOON USE FOR TEACHING TURKISH TO FOREIGNERS - YABANCILARA TÜRKÇE ÖĞRETİMİNDE ÇİZGİ FİLM KULLANIMI

    OpenAIRE

    Necmi AYTAN; tunçel, hayrettin

    2015-01-01

    The aim of the research is to determine how the use of cartoons in a functional direction impacts on students’ achievement in teaching Turkish as a foreign language. One group post-test model is designed to be used in qualitative research. The sample group of the research consists of 15 participants who study Turkish at A1-elementary level as a foreign language at TOMER in Antalya International University. In the study for the purpose of collecting data question paper which contains the quest...

  13. Nanoemulsion as a carrier to improve the topical anti-inflammatory activity of stem bark extract of Rapanea ferruginea

    Directory of Open Access Journals (Sweden)

    Dal Mas J

    2016-09-01

    Full Text Available Juarana Dal Mas,1 Tailyn Zermiani,1 Liliani C Thiesen,1 Joana LM Silveira,2 Kathryn ABS da Silva,1 Márcia M de Souza,1 Angela Malheiros,1 Tania MB Bresolin,1 Ruth M Lucinda-Silva1 1NIQFAR, Graduate Program in Pharmaceutical Sciences, University of Vale do Itajaí, Itajaí, Santa Catarina, Brazil; 2Department of Biochemistry and Molecular Biology, Federal University of Paraná, Curitiba, Paraná, Brazil Abstract: The aim of this study was to develop nanoemulsion containing soft extract of stem bark of Rapanea ferruginea to improve the topical delivery and anti-inflammatory activity. The extract of R. ferruginea stem bark was incorporated into the oily phase of the nanoemulsion by the method of phase inversion at low energy. The developed nanoemulsion had an average droplet size of 47.88±8.20 nm and a polydispersibility index of 0.228. Uniformity of size, spherical shape of droplet, and absence of clusters were confirmed by transmission electronic microscopy. The zeta potential was -34.7±1.15 mV. The nanoemulsion showed a moderate degree of skin irritation in the agarose overlay assay in vitro. The content of the extract markers, myrsinoic acids A and B, was 54.10±0.08 and 53.03 µg/g in the formulation, respectively. The formulation demonstrated pseudoplastic and thixotropic rheological behavior. In vitro release of chemical markers was controlled by diffusion mechanism. An extract-loaded nanoemulsion showed a topical anti-inflammatory activity in a croton oil-induced edema ear model, with a decrease in tumor necrosis factor release and myeloperoxidase activity. The nanoemulsion was 160% more efficient than the conventional cream containing 0.13% of the extract. The nanoemulsion showed suitable properties as a carrier for topical use of R. ferruginea extract and the approach for improving the topical anti-inflammatory activity. Keywords: nanotechnology, nanoemulsion, Rapanea ferruginea, anti-inflammatory, phytomedicine

  14. Novel alginate-based nanocarriers as a strategy to include high concentrations of hydrophobic compounds in hydrogels for topical application

    Science.gov (United States)

    Nguyen, H. T. P.; Munnier, E.; Souce, M.; Perse, X.; David, S.; Bonnier, F.; Vial, F.; Yvergnaux, F.; Perrier, T.; Cohen-Jonathan, S.; Chourpa, I.

    2015-06-01

    The cutaneous penetration of hydrophobic active molecules is of foremost concern in the dermatology and cosmetic formulation fields. The poor solubility in water of those molecules limits their use in hydrophilic forms such as gels, which are favored by patients with chronic skin disease. The aim of this work is to design a novel nanocarrier of hydrophobic active molecules and to determine its potential as an ingredient of a topical form. The nanocarrier consists of an oily core surrounded by a protective shell of alginate, a natural polysaccharide isolated from brown algae. These calcium alginate-based nanocarriers (CaANCs) were prepared at room temperature and without the use of organic solvent by an accelerated nanoemulsification-polymer crosslinking method. The size (hydrodynamic diameter ˜200 nm) and surface charge (zeta potential ˜ - 30 mV) of the CaANCs are both compatible with their application on skin. CaANCs loaded with a fluorescent label were stable in model hydrophilic galenic forms under different storage conditions. Curcumin was encapsulated in CaANCs with an efficiency of ˜95%, fully retaining its antioxidant activity. The application of the curcumin-loaded CaANCs on excised human skin led to a significant accumulation of the active molecules in the upper layers of the skin, asserting the potential of these nanocarriers in active pharmaceutical and cosmetic ingredients topical delivery.

  15. Same-sex families as a topic in the Nova Gorica kindergartens

    OpenAIRE

    Benko, Maja

    2013-01-01

    A family represents the beginning of someone's life. In the family a child acquires patterns, examples and directions for the future life. Families have their own sets of rules and functions which make the difference between them. As the families differ from each other, the same goes for individuals. The gender is one of the first divisions we face in our lives. It is assigned to us, although our opinion is not asked for. The gender is not a division between male and female. The social impact...

  16. TOPICAL REVIEW: Metallo-supramolecular modules as a paradigm for materials science

    Directory of Open Access Journals (Sweden)

    Dirk G Kurth

    2008-01-01

    Full Text Available Metal ion coordination in discrete or extended metallo-supramolecular assemblies offers ample opportunity to fabricate and study devices and materials that are equally important for fundamental research and new technologies. Metal ions embedded in a specific ligand field offer diverse thermodynamic, kinetic, chemical, physical and structural properties that make these systems promising candidates for active components in functional materials. A key challenge is to improve and develop methodologies for placing these active modules in suitable device architectures, such as thin films or mesophases. This review highlights recent developments in extended, polymeric metallo-supramolecular systems and discrete polyoxometalates with an emphasis on materials science.

  17. Formalin (0.25% as topical anti-microbial agent in burns.

    Directory of Open Access Journals (Sweden)

    Nair R

    1991-01-01

    Full Text Available In a prospective controlled trial, 0.25% formalin spray was compared with 2% silver sulfadiazine cream as the local treatment of burns. Formation and separation of eschar, infection and death rates were recorded. In the group receiving formalin, rates of formation and separation of eschar were significantly more (P less than 0.001 and P less than 0.05 resp. compared to other group. Infection rate and fatality due to infection were also reduced. Other advantages of formalin are ease of application and the low east.

  18. Studies on rheology and microbiological evaluation of hydrotropically gelled starch as topical vehicle for terbinafine hydrochloride

    Directory of Open Access Journals (Sweden)

    Rao Kovur

    2008-01-01

    Full Text Available The present study was aimed for the development and evaluation of hydrotropic starch gels of terbinafine hydrochloride which is an allylamine derivative of antifungal agent was formulated by using corn starch and sodium salicylate as hydrotropic salt. The gels were prepared in presence and absence of propylene glycol. The prepared gels were evaluated for in vitro drug release, rheological behavior and microbial studies. The degree of increase in the drug diffusion was found to be in order corn starch gel with propylene glycol was greater than corn starch gel without propylene glycol. The microbial studies were carried out in soya bean casein digest medium with Candida albicans as test organisms and were found to be 22.86 ± 0.58 and 20.22 ± 0.65 mm for TCSG (IV and TCS (III, respectively. All the gels exhibited shear thinning. The rheogram indicated that the gel systems are pseudoplastic and exhibited thixotropy. The added propylene glycol has not appreciably altered the apparent viscosity values.

  19. Topical report on sources and systems for aquatic plant biomass as an energy resource

    Energy Technology Data Exchange (ETDEWEB)

    Goldman, J.C.; Ryther, J.H.; Waaland, R.; Wilson, E.H.

    1977-10-21

    Background information is documented on the mass cultivation of aquatic plants and systems design that is available from the literature and through consultation with active research scientists and engineers. The biology of microalgae, macroalgae, and aquatic angiosperms is discussed in terms of morphology, life history, mode of existence, and ecological significance, as they relate to cultivation. The requirements for growth of these plants, which are outlined in the test, suggest that productivity rates are dependent primarily on the availability of light and nutrients. It is concluded that the systems should be run with an excess of nutrients and with light as the limiting factor. A historical review of the mass cultivation of aquatic plants describes the techniques used in commercial large-scale operations throughout the world and recent small-scale research efforts. This review presents information on the biomass yields that have been attained to date in various geographical locations with different plant species and culture conditions, emphasizing the contrast between high yields in small-scale operations and lower yields in large-scale operations.

  20. Time as a Key Topic in Health Professionals’ Perceptions of Clinical Handovers

    Directory of Open Access Journals (Sweden)

    Bernadette M. Watson

    2014-10-01

    Full Text Available Clinical handovers are an essential part of the daily care and treatment of hospital patients. We invoked a language and social psychology lens to investigate how different health professional groups discussed the communication problems and strengths they experienced in handovers. We conducted in-depth interviews with three different health professional groups within a large metropolitan hospital. We used Leximancer text analytics software as a tool to analyze the data. Results showed that time was of concern to all groups in both similar and diverse ways. All professionals discussed time management, time pressures, and the difficulties of coordinating different handovers. Each professional group had its own unique perceptions and priorities about handovers. Our findings indicated that health professionals understood what was required for handover improvement but did not have the extra capacity to alter their current environment. Hospital management, with clinicians, need to implement handover schedule processes that prioritize interprofessional representation.

  1. [Topical contraceptives].

    Science.gov (United States)

    Alipov, V I; Korkhov, V V

    1982-02-01

    Recently there has been little interest in topical contraceptives. The most popular are the cervical cap and the diaphragm. Other types of mechanical contraceptive devices are being investigated. Standley and Kessler have developed a device for introduction into the cervical canal with a reservoir of spermatocide, it does not block the flow of blood during menstruation. New models of vaginal rings are also being developed which are simple enough for self-insertion and also contain a reservoir of spermatocide. Work is being done on spermatocide-containing sponges in many countries. Another project being investigated is the possibility of using natural proteins, collagens, and other substances which absorb spermatozoids. The ancients used various vaginal suppositories to kill spermatozoids; in the late 19th century quinine sulfate was used for this, and a variety of substances have been used recently. These spermicidal creams also have the advantage of acting as anti-infectious agents in many cases. But they do have some negative effects. They are about 85% effective, are local irritants, and some cause discomfort during intercourse. And it is possible that some are resorbed by the body and act on the liver and other organs. Vaginal globules and suppositories are also popular. The "Kontraceptin-T" brand contains quinosol, boric acid, and tannin. There are also foaming tablets which are mixed with water and then introduced. New locally-active chemical substances are being developed in Japan, West Germany, and the USSR. Kontraceptin-E contains paranonyl-phenoxypolyethylene glycol and sodium dioctylsulfosuccinate. The "Norforks" and other preparations contain mercurial compounds which may turn out to be harmful. The future promises the development of products which will act to prevent fertilization by acting on the hyaluronidase and the acrosine of the spermatozoid, thus preventing it from penetrating the ovum. It would be best to find enzyme inhibitors which are

  2. Bicellar systems as new delivery strategy for topical application of flufenamic acid.

    Science.gov (United States)

    Rubio, L; Alonso, C; Rodríguez, G; Cócera, M; López-Iglesias, C; Coderch, L; De la Maza, A; Parra, J L; López, O

    2013-02-28

    In this work, bicellar systems, bilayered disc-shaped nanoaggregates formed in water by phospholipids, are proposed as a novel strategy for delivery of the anti-inflammatory flufenamic acid (FFA) to the skin. A comparative percutaneous penetration study of this drug in bicellar systems and other vehicles was conducted. The effects induced on the skin by the application of FFA in the different vehicles were analyzed by attenuated total reflectance-fourier transform infrared (ATR-FTIR). Additionally, using the microscopic technique freeze-substitution transmission electron microscopy (FSTEM) and X-ray scattering technique using synchrotron radiation (SAXS-SR), we studied the possible microstructural and organizational changes that were induced in the stratum corneum (SC) lipids and the collagen of the skin by the application of FFA bicellar systems. Bicellar systems exhibited a retarder effect on the percutaneous absorption of FFA with respect to the other vehicles without promoting disruption in the SC barrier function of the skin. Given that skin disruption is one of the main effects caused by inflammation, prevention of disruption and repair of the skin microstructure should be prioritized in anti-inflammatory formulations. PMID:23357252

  3. Ethosomes and liposomes as topical vehicles for azelaic acid: a preformulation study.

    Science.gov (United States)

    Esposito, Elisabetta; Menegatti, Enea; Cortesi, Rita

    2004-01-01

    The basic properties and the in vitro release rate kinetics of azelaic acid (AA), alternatively vehiculated in different phospholipid-based vesicles such as ethosomes or liposomes, were investigated. Ethosomes were produced by a simple method based on addition of an aqueous phase to an ethanol solution (comprised between 20\\% and 45%, v/v) of soy phosphatidyl choline (5%, w/w) and AA (0.2%, w/w) under mechanical stirring. Liposomes were obtained by the same composition in the absence of ethanol with the reverse-phase evaporation method. Vesicle size was measured by photon correlation spectroscopy (PCS), evidencing smaller mean diameters and narrower dimensional distributions in the case of ethosomes with respect to liposomes. In order to obtain homogeneously sized vesicles, both ethosomal and liposomal dispersions were extruded through polycarbonate membranes with pores of calibrated diameter (400 nm and 200 nm). Vesicle morphology was characterized by freeze-fracture scanning electron microscopy (SEM) showing the presence of unilamellar vesicles both in liposome- and in ethosome-based dispersions. Free energy measurements of the vesicle bilayers were conducted by differential scanning calorimetry (DSC). AA diffusion from ethosomal or liposomal dispersions and from ethosomes and liposomes incorporated in a viscous gel was investigated by a Franz cell assembled with synthetic membranes. The release rate was more rapid from ethosomal systems than from liposomal systems. In particular, ethosomes produced by the highest ethanol concentration released AA more rapidly, and the same trend was found using viscous forms.

  4. Development of backfill material as an engineered barrier in the waste package system. Interim topical report

    International Nuclear Information System (INIS)

    A backfill barrier, emplaced between the containerized waste and the host rock, can both protect the other engineered barriers and act as a primary barrier to the release of radionuclides from the waste package. Attributes that a backfill should provide in order to carry out its required function have been identified. Primary attributes are those that have a direct effect upon the release and transport of radionuclides from the waste package. Supportive attributes do not directly affect radionuclide release but are necessary to support the primary attributes. The primary attributes, in order of importance, are: minimize (retard or exclude) the migration of ground water between the host rock and the waste canister system; retard the migration of selected chemical species (corrosive species and radionuclides) in the ground water; control the Eh and pH of the ground water within the waste-package environment. The supportive attributes are: self-seal any cracks or discontinuities in the backfill or interfacing host geology; retain performance properties at all repository temperatures; retain peformance properties during and after receiving repository levels of gamma radiation; conduct heat from the canister system to the host geology; retain mechanical properties and provide resistance to applied mechanical forces; retain morphological stability and compatibility with structural barriers and with the host geology for required period of time. Screening and selection of candidate backfill materials has resulted in a preliminary list of materials for testing. Primary emphasis has been placed on sodium and calcium bentonites and zeolites used in conjunction with quartz sand or crushed host rock. Preliminary laboratory studies have concentrated on permeability, sorption, swelling pressure, and compaction properties of candidate backfill materials

  5. Nanoemulsion Therapy for Burn Wounds Is Effective as a Topical Antimicrobial Against Gram-Negative and Gram-Positive Bacteria.

    Science.gov (United States)

    Dolgachev, Vladislav A; Ciotti, Susan M; Eisma, Rone; Gracon, Stephen; Wilkinson, J Erby; Baker, James R; Hemmila, Mark R

    2016-01-01

    The aim of this study is to investigate the antimicrobial efficacy of two different nanoemulsion (NE) formulations against Gram-positive and Gram-negative bacteria in an in vivo rodent scald burn model. Male Sprague-Dawley rats were anesthetized and received a partial-thickness scald burn. Eight hours after burn injury, the wound was inoculated with 1 × 10(8) colony-forming units of Pseudomonas aeruginosa or Staphylococcus aureus. Treatment groups consisted of two different NE formulations (NB-201 and NB-402), NE vehicle, or saline. Topical application of the treatment was performed at 16 and 24 hours after burn injury. Animals were killed 32 hours after burn injury, and skin samples were obtained for quantitative wound culture and determination of dermal inflammation markers. In a separate set of experiments, burn wound progression was measured histologically after 72 hours of treatment. Both NE formulations (NB-201 and NB-402) significantly reduced burn wound infections with either P. aeruginosa or S. aureus and decreased median bacterial counts at least three logs when compared with animals with saline applications (p wound as measured by myeloperoxidase (MPO) assay and histopathology (p wound progression 72 hours after injury. Topically applied NB-201 and NB-402 are effective in decreasing Gram-positive and Gram-negative bacteria growth in burn wounds, reducing inflammation, and abrogating burn wound progression. PMID:26182074

  6. Exploring the Abyss. The Financial Crisis of 2008 ff. as a Central Topic of Problem-Centered Social Science Education

    Directory of Open Access Journals (Sweden)

    Thorsten Hippe

    2010-07-01

    Full Text Available The financial crisis of 2008 ff. and financial crises in general should be a central topic of social science education because these crises are a recurrent and therefore structural feature of modern capitalism which has severe consequences for citizens’ quality of life. Hence, the citizenry should know how to prevent such developments which endanger its well-being in a massive way. Therefore, learners should understand the relationship between the quality of people’s everyday lives and those economic institutions and political decisions which have led to the current mess. They should be enabled to critically evaluate the current misregulation of the financial sector and the economy in order to identify possible policy measures to prevent or at least to mitigate future crises. By educating (young citizens in this way, the (future general public can – as a necessary counterweight to the lobbyism of the finance industry – exert more prudent political pressure which gives politicians a greater incentive to regulate the financial sector and the economy in a manner which is beneficial for the vast majority of the people instead of for a small elite. Two core concepts of the social sciences can be used to make the roots of the seemingly complex topic more understandable for learners: liability and inequality.

  7. Phosphatidylcholine liposomes as carriers to improve topical ascorbic acid treatment of skin disorders

    Directory of Open Access Journals (Sweden)

    Serrano G

    2015-12-01

    Full Text Available Gabriel Serrano,1,* Patricia Almudéver,2,* Juan-Manuel Serrano,1 Javier Milara,2–5 Ana Torrens,1 Inmaculada Expósito,1 Julio Cortijo2–51Sesderma Laboratorios, 2Department of Pharmacology, Faculty of Medicine, University of Valencia, 3Clinical Research Unit, University General Hospital Consortium, 4CIBERES, Health Institute Carlos III, 5Research Foundation of the University General Hospital of Valencia, Valencia, Spain*These authors contributed equally to this workAbstract: Liposomes have been intensively investigated as carriers for different applications in dermatology and cosmetics. Ascorbic acid has potent antioxidant and anti-inflammatory properties preventing photodamage of keratinocytes; however, due to its instability and low skin penetration, an appropriate carrier is mandatory to obtain desirable efficacy. The present work investigates the ability of a specific ascorbate phosphatidylcholine (PC liposome to overcome the barrier of the stratum corneum and deliver the active agent into the dermis to prevent photodamage. Abdominal skin from ten patients was used. Penetration of PC liposomes was tested ex vivo in whole skin, epidermis, and dermis by means of fluorescein and sodium ascorbate. Histology and Franz diffusion cells were used to monitor the percutaneous absorption. Ultraviolet (UV-high performance liquid chromatography was used to analyze diffusion of sodium ascorbate through the different skin layers, while spectrofluorimetry and fluorescent microscopy were used for fluorescein monitoring. UVA/UVB irradiation of whole skin was applied to analyze the antioxidant capacity by Trolox assay and anti-inflammatory effects by tumor necrosis factor alpha and interleukin 1 beta enzyme-linked immunoassay. PC liposomal formulation improved skin penetration of fluorescein and ascorbate. Fluorescein PC liposomes showed better diffusion through epidermis than dermis while ascorbate liposomes showed better diffusion through the dermis than

  8. 卡通标志及其品格特质%Cartoon Logo and Its Peculiarity of Brand Personality

    Institute of Scientific and Technical Information of China (English)

    曹汝平; 李中扬

    2012-01-01

    From the recognition of cartoon logos, it analyzed the brand connotation of cartoon logos, and based on brand personality theory & its psychological vocabulary method, proposed that the cartoon logos having four Peculiarity of Brand personality: optimist, affinity, sincerity, flexibility. It emphasized the value of human in the cartoon-logo's brand value from different personality dimensions. Finally, it tried to clarify the meaning of cartoon logos on humanity which is to promote the cartoon logos design level of the whole.%从对卡通及卡通标志的认识出发,分析了卡通标志在大众消费社会中的品牌内涵,依据品牌人格理论及其中的心理词汇法提出卡通标志所具有的4种"品格"特质,即乐观、亲和、真诚、灵活,并结合相关实例从不同的人格维度强调了卡通标志中人的价值。最终明晰了卡通标志人性化的意义,以实现卡通标志设计在品牌运作中的整体提升。

  9. Novel aqueous chitosan-based dispersions as efficient drug delivery systems for topical use. Rheological, textural and release studies.

    Science.gov (United States)

    Lucero, M J; Ferris, C; Sánchez-Gutiérrez, C A; Jiménez-Castellanos, M R; de-Paz, M-V

    2016-10-20

    The use of a novel cross-linked thiolated chitosan (CTS) was investigated as the main component of aqueous dispersions (at 1% and 3% w/v) for topical drug delivery systems. The nonionic theophiline (Th) and the cationic diltiazem(.)HCl (Dt) (at 0.5% w/v concentration) were used as model drugs. All aqueous dispersions behaved as viscoelastic fluids. The CTS 1% dispersions showed predominance of viscous component and low viscosity. However, in the CTS 3% dispersions, both the elastic component and high viscosities prevailed. So, texture parameters improved from CTS 1% to 3% dispersions and CTS 3%-Dt showed greater cohesion and adhesion than CTS 3%-Th, but always below CTS alone. All dispersions showed a Fickian diffusion mechanism. Despite release profiles of both drugs almost fully overlapped at 1% CTS, diffusion coefficients confirmed Dt released faster than Th at 3% CTS. The rheological behavior and the chemical nature of the drugs explained these results. PMID:27474615

  10. 卡通图形语言在标志设计中的应用%Application of Cartoon Graphics Language in Logo Design

    Institute of Scientific and Technical Information of China (English)

    梁遗鹏

    2016-01-01

    卡通图形语言作为现代标志设计的新亮点,具有通俗、直观,易于理解和记忆的特点。它们或是活泼可爱,或是沉稳内敛,其所体现出的生命力、亲和力、可辨识性及其时代表征,对标志设计品牌的“性格”塑造与推广起到了很好的效果。如何认识卡通图形,在标志设计中如何将符号语言与卡通图形智慧的衔接与应用,一直是学界颇受关注的问题。本文试图触及这方面的应用和研究,抛砖引玉,以期获得同仁对这方面的关注和探研。%New highlights cartoon graphics language as modern logo design, with popular, intuitive, easy to understand and remember features. They are either lovely or calm restrained, it reflects the vitality, affinity, and the era of identifiability char-acterization of logo design brand"personality"Creation and promotion played a very good effect. How to understand the car-toon graphics, the logo design and how to use sign language and Cohesion cartoon graphics wisdom, it has been a flurry of aca-demic problems. This paper attempts to touch the application and research in this area, initiate, to gain attention and exploration research colleagues in this regard.

  11. The Case of the Danish Cartoons Controversy: The Paradox of Civility

    DEFF Research Database (Denmark)

    Lægaard, Sune

    2014-01-01

    The so-called ‘Danish cartoons controversy’ set in motion by the publication of twelve drawings under the title ‘the face of Mohammed’ by the Danish broadsheet Jyllands-Posten in September 2005 has become one of the iconic controversies surrounding Islam in Europe. But the cartoon controversy...... to understand how some views and interventions in the controversy were displaced or misrepresented, which gave defenders of Jyllands-Posten a rhetorical advantage that allowed them to dominate the controversy, at least in Denmark. But the very framing of the debate in terms of civility also leads to a problem...... due to the discursive logic of civility claims. This ‘paradox of civility’ is a practical problem facing any attempt by minority groups to raise issues of civility. This discursive phenomenon might have empirical explanatory significance, since the logic of claims of civility might explain some...

  12. Cartoons on bacterial balloons: scientists' opinion on the popularization of synthetic biology.

    Science.gov (United States)

    Domínguez, Martí; Mateu, Anna; Torgersen, Helge; Porcar, Manuel

    2014-12-01

    How do scientists perceive the media coverage of synthetic biology (SB)? In this paper, we approach this question by studying a set of cartoons devoted to SB. Based on a categorization of the cartoons into five large thematic groups an international survey was carried out to assess the opinion of SB research groups on science communication with regard to the public image of their discipline. The 101 responses obtained indicate that in general, their perception of the communication is not negative, although many respondents raised concerns on the media's inclination to sensationalism and over-simplification. However, the results also suggest that (in the light of the unfortunate experiences with GMO communication) scientists should think twice before proposing metaphorical interpretations of their research.

  13. The Legal Position of Migrants in Denmark: Assessing the Context around the "Cartoon Crisis"

    DEFF Research Database (Denmark)

    Adamo, Silvia

    2007-01-01

    Abstract What can we infer from the legal status of migrants living in Denmark? This article argues that understanding recent developments in Danish immigration law is essential for comprehending contemporary political tensions in this policy area, including notably the cartoon incident. The anal......Abstract What can we infer from the legal status of migrants living in Denmark? This article argues that understanding recent developments in Danish immigration law is essential for comprehending contemporary political tensions in this policy area, including notably the cartoon incident....... The analysis offered focuses on general principles and practical notions of Danish immigration and refugee law, integration policies and regulations in light of international legal obligations, rules on family reunification, and the growing importance of citizenship status and anti-terrorism measures. Keywords...

  14. A preliminary study of a cartoon measure for children's reactions to chronic trauma.

    Science.gov (United States)

    Praver, F; DiGiuseppe, R; Pelcovitz, D; Mandel, F S; Gaines, R

    2000-08-01

    Preliminary psychometric properties of a new instrument, Angie/Andy Cartoon Trauma Scales (ACTS), are presented. Angie/Andy features a cartoon-based methodology, measuring trauma-related sequelae of prolonged, repeated abuse. A sample of 208 children comprised intrafamilial trauma, extrafamilial trauma, combined trauma, and nontrauma groups. Angie/Andy demonstrated high internal consistency, with coefficient alphas from 0.70 to 0.95. The three trauma groups scored significantly higher than the nontrauma group on all scales (p's violence exposures correlated with Angie/Andy scores from 0.55 to 0.74. The frequency and severity of trauma exposure correlated with Angie/Andy scores from 0.44 to 0.56. The Angie/Andy parent version correlated with a standardized parent scale from 0.71 to 0.81. Parent/child agreement was significant. Angie/Andy is a promising tool for clinical assessment of chronic childhood abuse. PMID:11232273

  15. Cartoons on bacterial balloons: scientists' opinion on the popularization of synthetic biology.

    Science.gov (United States)

    Domínguez, Martí; Mateu, Anna; Torgersen, Helge; Porcar, Manuel

    2014-12-01

    How do scientists perceive the media coverage of synthetic biology (SB)? In this paper, we approach this question by studying a set of cartoons devoted to SB. Based on a categorization of the cartoons into five large thematic groups an international survey was carried out to assess the opinion of SB research groups on science communication with regard to the public image of their discipline. The 101 responses obtained indicate that in general, their perception of the communication is not negative, although many respondents raised concerns on the media's inclination to sensationalism and over-simplification. However, the results also suggest that (in the light of the unfortunate experiences with GMO communication) scientists should think twice before proposing metaphorical interpretations of their research. PMID:26396656

  16. ASSESSMENT OF EFFICACY OF TOPICAL PHENYTOIN SODIUM DRESSING AS COMPARED TO CONVENTIONAL MOIST DRESSING IN THE MANAGEMENT OF LEG ULCERS

    Directory of Open Access Journals (Sweden)

    Srikanth Reddy

    2015-10-01

    Full Text Available Chronic leg ulcers are one of the most common surgical conditions in surgical practice. From times immemorial, many methods have been tried to treat these types of ulcers. Many techniques have been tried over the centuries to aid in healing of chronic leg ulcers, but there exists no ideal dressing till date.(1 Phenytoin Sodium, a chemical used in management of Epilepsy, is known to produce gingival Hyperplasia, an indirect evidence to enhanced Fibroblastic activity. The present study was conducted to assess the efficacy of topical Phenytoin solution dressing as compared to conventional moist dressing in the healing process of chronic leg ulcers. Phenytoin Sodium being a cheap drug, is likely to cut down, the cost burden on the individual and the Society, if proven effective.

  17. Impact of Educational Cartoon on Pediatric Bowel Preparation Quality at Time of Colonoscopy

    Directory of Open Access Journals (Sweden)

    Elizabeth Maxwell MD

    2014-08-01

    Full Text Available Objective: To evaluate if addition of educational cartoon to pediatric bowel preparation instructions improves the quality of bowel preparation and patient experience. Methods: Patients were randomized to control group receiving standard bowel preparation instructions or intervention group receiving additional educational cartoon. To objectively rate bowel preparation, a blinded endoscopist completed numeric Ottawa score (0-14, with 0 being best. The family also completed a questionnaire rating the bowel preparation process. Results: Data from 23 patients were analyzed. Mean Ottawa score in the intervention group compared with controls was not significantly different (mean scores 3.73 and 3.33, respectively; P = .384. Level of education was significantly correlated with better Ottawa score in the overall population (ρ = −.462, P = .026 and within the control group (ρ = −.658, P = .02. Both groups of patients reported positive experience with bowel preparation. Conclusion: There may be benefit to further investigation of this educational cartoon in parents with less than college level education or non-English-speaking families in larger population of patients.

  18. Histatin 5-spermidine conjugates have enhanced fungicidal activity and efficacy as a topical therapeutic for oral candidiasis.

    Science.gov (United States)

    Tati, Swetha; Li, Rui; Puri, Sumant; Kumar, Rohitashw; Davidow, Peter; Edgerton, Mira

    2014-01-01

    Oropharyngeal candidiasis (OPC) is caused by the opportunistic fungi Candida albicans and is prevalent in immunocompromised patients, individuals with dry mouth, or patients with prolonged antibiotic therapies that reduce oral commensal bacteria. Human salivary histatins, including histatin 5 (Hst 5), are small cationic proteins that are the major source of fungicidal activity of saliva. However, Hsts are rapidly degraded in vivo, limiting their usefulness as therapeutic agents despite their lack of toxicity. We constructed a conjugate peptide using spermidine (Spd) linked to the active fragment of Hst 5 (Hst 54-15), based upon our findings that C. albicans spermidine transporters are required for Hst 5 uptake and fungicidal activity. We found that Hst 54-15-Spd was significantly more effective in killing C. albicans and Candida glabrata than Hst 5 alone in both planktonic and biofilm growth and that Hst 54-15-Spd retained high activity in both serum and saliva. Hst 54-15-Spd was not bactericidal against streptococcal oral commensal bacteria and had no hemolytic activity. We tested the effectiveness of Hst 54-15-Spd in vivo by topical application to tongue surfaces of immunocompromised mice with OPC. Mice treated with Hst 54-15-Spd had significant clearance of candidal tongue lesions macroscopically, which was confirmed by a 3- to 5-log fold reduction of C. albicans colonies recovered from tongue tissues. Hst 54-15-Spd conjugates are a new class of peptide-based drugs with high selectivity for fungi and potential as topical therapeutic agents for oral candidiasis.

  19. Water-filtered infrared-A (wIRA) can act as a penetration enhancer for topically applied substances

    OpenAIRE

    Sterry, Wolfram; Ackermann, Hanns; Hoffmann, Gerd; Schanzer, Sabine; Meyer, Lars; Grone, Diego; Otberg, Nina; Lademann, Jürgen

    2008-01-01

    Background: Water-filtered infrared-A (wIRA) irradiation has been shown to enhance penetration of clinically used topically applied substances in humans through investigation of functional effects of penetrated substances like vasoconstriction by cortisone. Aim of the study: Investigation of the influence of wIRA irradiation on the dermatopharmacokinetics of topically applied substances by use of optical methods, especially to localize penetrating substances, in a prospective randomised contr...

  20. An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine

    OpenAIRE

    Judd, Amy Maryanne

    2013-01-01

    The reduction of bacteria on the skin results in prophylactic and therapeutic benefits by reducing the occurrence of skin infections. Currently, chlorhexidine digluconate, a conventional topical antiseptic, permeates the skin poorly leaving viable opportunistic pathogens below the superficial layers of the stratum corneum. The aim of this study was to use polyamidoamine (PAMAM) dendrimers to enhance the topical delivery of chlorhexidine digluconate to improve its antimicrobial efficacy.

  1. The Big Five, Self-Esteem, and Narcissism as Predictors of the Topics People Write About in Facebook Status Updates

    OpenAIRE

    Marshall, TC; Lefringhausen, K; Ferenczi, N

    2015-01-01

    Status updates are one of the most popular features of Facebook, but few studies have examined the traits and motives that influence the topics that people choose to update about. In this study, 555 Facebook users completed measures of the Big Five, self-esteem, narcissism, motives for using Facebook, and frequency of updating about a range of topics. Results revealed that extraverts more frequently updated about their social activities and everyday life, which was motivated by their use of F...

  2. The Genetic Principle as a Link between Everyday Knowledge and Politics - The Art-of-Teaching Workshop about the Topic "Future"

    OpenAIRE

    Andreas Petrik

    2004-01-01

    This article demonstrates, how didactics of social sciences can turn its focus from theoretical conceptions to the arrangement of learning processes. It simulates a best practice ("Lehrkunst") workshop (I.1.) which compares seven teaching units about the key topic "future" (I.2.). Two typical problems become concrete: exchangeable topics and the transfer to abstract categories. The genetic principle is introduced as a possible remedy: It combines categories with concepts and chooses special t...

  3. Water-filtered infrared-A (wIRA can act as a penetration enhancer for topically applied substances

    Directory of Open Access Journals (Sweden)

    Sterry, Wolfram

    2008-07-01

    increased penetration depth compared to the non-irradiated skin (mode A: The ratio of the amount of the dye in the deeper (second 10% of the stratum corneum to the amount of the dye in the upper 10% of the stratum corneum showed medians and interquartile ranges for mode A of 0.017 (0.007/0.050, for mode B of 0.084 (0.021/0.106, for mode C of 0.104 (0.069/0.192 (difference between modes: p=0.0112, significant; comparison mode A with mode C: p<0.01, significant. In contrast to fluorescein, the lipophilic curcumin showed no differences in the penetration kinetics, in reference to whether the skin was irradiated with wIRA or not. These effects were confirmed by laser scanning microscopy. Water-filtered infrared-A irradiation increased the hydration of the stratum corneum: transepidermal water loss rose from approximately 8.8 g m-2 h-1 before wIRA irradiation to 14.2 g m-2 h-1 after wIRA irradiation and skin hydration rose from 67 to 87 relative units. Skin surface temperature increased from 32.8°C before wIRA to 36.4°C after wIRA irradiation. Discussion: The better penetration of the hydrophilic dye fluorescein after or during skin irradiation (modes B and C can be explained by increased hydration of the stratum corneum by irradiation with wIRA. Conclusions: As most topically applied substances for the treatment of patients are mainly hydrophilic, wIRA can be used to improve the penetration of substances before or after application of substances – in the first case even of thermolabile substances – with a broad clinical relevance as a contact free alternative to an occlusive dressing.

  4. Preoperative subconjunctival injection of mitomycin C versus intraoperative topical application as an adjunctive treatment for surgical removal of primary pterygium

    Directory of Open Access Journals (Sweden)

    Ehab M Ghoneim

    2011-01-01

    Materials and Methods : Seventy eyes of 70 patients with primary pterygia were randomly allocated to two groups. The first group (Group A, 35 eyes received 0.1 ml of 0.15 mg/ml of subconjunctival MMC injected into the head of the pterygium 24 h before surgical excision with the bare sclera technique. The second group (Group B 35 eyes underwent surgical removal with the bare sclera technique with intraoperative application of MMC (0.15 mg/ml over bare sclera for 3 min. The study was performed between March 2007 and December 2008, and follow up was performed for 1 year postoperatively. Differences between frequencies in both groups were compared by the Chi-square test or Fisher exact test. Differences between means in both groups were compared by Student′s t-test. P 0.05. Postoperatively, scleral thinning occurred in one eye in each group that resolved by 5 months postoperatively. No serious postoperative complications occurred in either group. Conclusion : Preoperative local injection of 0.15 mg/ml MMC is as effective as intraoperative topical application of 0.15 mg/ml MMC for preventing pterygium recurrence after surgical removal.

  5. Serum corticosterone as a quantitative test of the phlogistic potency of various agents topically applied in the rat.

    Science.gov (United States)

    Giagnoni, G; Marsi, A; Parolaro, D; Sala, M; Gori, E

    1976-12-01

    The application into the rat conjunctiva of various phlogistic agents, such as croton oil, mustard oil and formaldehyde, elicits an increase of serum corticosterone linearly related to the log of the applied concentrations, so that from their parallelized regression lines it is possible to calculate the phlogistic potency of each tested agent in reference to croton oil. The time kinetic of such an increase (elicited by croton oil) is compared with that of two other parameters previously adopted as indirect quantitative indices of the phlogosis: the adrenal ascorbic acid depletion and the liver tyrosine-alpha-ketoglutarate transaminase increase. Serum corticosterone is shown to be the quickest and the most sensitive of the adopted indices, even if the phlogistic potency of the tested agents and the precision of these evaluations substantially coincides whatsoever the index adopted. Finally the pathways of adrenocortical activation are investigated and it is shown that the activation may be peripherally blocked by topical application of corticosteroids (but not of local anesthetics) and centrally by hypophysectomy or parenteral administration of pentobarbital plus morphine. PMID:13751

  6. A case of topical opioid-induced delirium mistaken as behavioural and psychological symptoms of dementia in demented state.

    Science.gov (United States)

    Ito, Go; Kanemoto, Kousuke

    2013-06-01

    In Japan, indications for opioid analgesics, once exclusively used as pain killers for patients suffering from malignant cancer, have been expanded for a wide range of pain. Herein we report a patient with opioid-induced delirium associated with the administration of buprenorphine patches that was well below the indicated therapeutic range limit. An 82-year-old woman was referred to us from an orthopaedic practitioner for uncontrollable behavioural problems apparently caused by the beginning of dementia; the patient had gradually developed disorientation, visual hallucinations, and delusions. Laboratory and imaging findings excluded common causes of delirium including Alzheimer's disease and diffuse Lewy body disease. Detailed questioning revealed that the patient's confused state appeared following a buprenorphine patch dose increase and subsequently disappeared after administration was stopped. Delirium has not been reported as a side-effect in clinical trials of buprenorphine patches. However, our findings in this case show that even topical opioids can precipitate the development of a delirious state in elderly patients.

  7. Non-occlusive topical exposure of human skin in vitro as model for cytotoxicity testing of irritant compounds.

    Science.gov (United States)

    Lönnqvist, Susanna; Briheim, Kristina; Kratz, Gunnar

    2016-02-01

    Testing of irritant compounds has traditionally been performed on animals and human volunteers. Animal testing should always be restricted and for skin irritancy mice and rabbits hold poor predictive value for irritant potential in humans. Irritant testing on human volunteers is restricted by the duration subjects can be exposed, and by the subjectivity of interpreting the visual signs of skin irritation. We propose an irritant testing system using viable human full thickness skin with the loss of cell viability in the exposed skin area as end point measurement. Skin was exposed to sodium dodecyl sulfate (SDS) at 20% concentration by non-occluded topical exposure to establish a positive control response and subsequent test compounds were statistically compared with the 20% SDS response. Cell viability and metabolism were measured with 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay. The model presents correlation between increased concentration of SDS and decreased viability of cells in the exposed skin area (R(2) = 0.76). We propose the model to be used for cytotoxicity testing of irritant compounds. With fully intact barrier function, the model comprises all cells present in the skin with quantifiable end point measurement. PMID:26446981

  8. Comparative study of the topical effectiveness of the Andiroba oil (Carapa guianensis) and DEET 50% as repellent for Aedes sp.

    Science.gov (United States)

    Miot, Hélio Amante; Batistella, Rafaelle Fernandes; Batista, Khristiani de Almeida; Volpato, Dimas Eduardo Carneiro; Augusto, Leonardo Silveira Teixeira; Madeira, Newton Goulart; Haddad, Vidal; Miot, Luciane Donida Bartoli

    2004-01-01

    DEET (N,N-diethyl-3-methylbenzamide) is nowadays the most effective mosquito repellent available, however, its use can present some topical and systemic side effects. Some botanical compositions, as Andiroba (Carapa guianensis), have been proved repellent properties at low cost and toxicity. An experimental study was driven involving four volunteers submitting their forearms covered with Andiroba oil at 100%, DEET 50%, refined soy oil, Andiroba oil 15% and in the absence of products, directly to healthy females of Aedes sp. The times of first and third bites were checked. The results showed that the median of the first bite without any product was 17.5s and the third bite, 40.0s. In the soy oil, the bites happened in 60.0s and 101.5s, in the presence of Andiroba oil 100%, in 56.0s and 142.5s and in Andiroba oil 15%, in 63.0s and 97.5s. The volunteers using DEET 50% had not received bites after 3600s in most of the experiments (p Andiroba oil compared to the soy oil, forearm without product and Andiroba oil 15%, showed discreet superiority (p Andiroba oil presents discreet repellent effect against bite of Aedes sp., being significantly inferior to DEET 50%. PMID:15517027

  9. 动漫游戏中虚拟角色的一种情绪行为仿真模型%Simulation Model of Emotional Behavior for Virtual Characters in Cartoon Games

    Institute of Scientific and Technical Information of China (English)

    刘琼; 刘箴; 卞玉龙

    2011-01-01

    情绪在人类的生活中扮演了重要角色,情绪仿真已经成为许多领域中令人感兴趣的研究课题,为了使计算机具有情绪表达能力,应该将人类情绪运用合适的数学模型描述出来。选择功度游戏中的追逐行为作为仿真对象。结合人体生物学原理和环境心理学理论.提出了追逐行为的情绪仿真模型,将博彝思想引入纠追逐行模拟中,仿真原型系统显示本模型能较好地描述虚拟角色的追逐行为。%Emotion plays an important role in human life, and emotion simulation is an interesting research topic in many fields. In order to make the computer be capable of emotion expression, a suitable mathematical model should be first used to describe human emotions. Chasing behavior was selected as a research object in cartoon games and biological principles of human and environmental psychology theory were used, a simulation model of emotional chasing behavior was proposed, and Game Theory was introduced to model chasing behavior. A simulation demo system shows that the model can better describe chasing behavior of virtual characters.

  10. Sex Role Stereotypes on Children's TV in Asia: A Content Analysis of Gender Role Portrayals in Children's Cartoons in Hong Kong.

    Science.gov (United States)

    Chu, Donna; McIntyre, Bryce T.

    1995-01-01

    Finds that male characters outnumbered female characters by a ratio of 2:1, but that female characters enjoyed far greater representation in cartoons produced in Japan than in cartoons produced in the United States and Great Britain. Shows that characters conformed to gender-related stereotypes, with males being more aggressive, rough, sloppy, and…

  11. Women's Rights international cartoon contest and exhibition-to support women and the rise a global voice against oppression, violence and injustice of women. 2016

    OpenAIRE

    Mumberson, Stephen

    2016-01-01

    Contest had 567 cartoonists from 79 countries who submitted 1625 cartoons .Show organized by tOOns MaG -worlds first on line cartoon magazine.The work of the winners and other cartoonists to be shown in Norway and two venues in India.All work on the theme of Women's rights.

  12. Children’s identification processes with television characters: case studies about colombian children and their favorite cartoon programs.

    Directory of Open Access Journals (Sweden)

    Luis Fernando Cuervo

    2013-12-01

    Full Text Available Through the articulation of psychoanalysis and narrative analysis this study explores the processes of identification of children audiences with their favorite cartoon television programs. In order to understand the characteristics of identification processes, this study explores the way in which both the structure of cartoons and the affective histories of children influence children’s identification with their favorite television characters. To achieve that understanding we a analyzed the narrative elements of the television programs, b explored the children’s affective history, and c examined how these narrative elements and affective histories influence the appropriation of television programs. These three scenarios were examined through case study on four Colombian children between 6 to 10 years old. The analysis showed that affective factors of children’s personal history constitute a significant source of mediation on the appropriation of cartoons. In addition, the narrative elements of the programs become an essential motivation on children’s fantasies.

  13. The Role of Topical Brimonidine Tartrate Gel as a Novel Therapeutic Option for Persistent Facial Erythema Associated with Rosacea.

    Science.gov (United States)

    Johnson, Andrew William; Johnson, Sandra Marchese

    2015-09-01

    Rosacea is a chronic inflammatory skin condition that commonly presents with persistent facial erythema with or without the coincident presence of flushing, telangiectasias, inflammatory papules or pustules, phymatous changes, or ocular involvement. Patients often present with a constellation of various signs and symptoms of the disease, and an individualized treatment plan should be tailored to a patient's unique clinical presentation. Previously available medications for rosacea have all targeted the inflammatory erythematous papules and pustules frequently associated with the disease, leaving a therapeutic gap for the common manifestation of persistent facial erythema. Brimonidine tartrate 0.33% gel was approved by the US Food and Drug Administration in August 2013 as the first medication available for the topical treatment of persistent facial erythema associated with rosacea. Brimonidine gel is a highly selective α2-adrenergic receptor agonist with potent vasoconstrictive effects, which leads to significant reduction of persistent facial erythema in the majority of patients when applied once daily. Based on large-scale clinical trials and post-marketing reports, brimonidine gel has maintained a good safety profile with a minority of patients experiencing adverse effects from its use, most of which are cutaneous in nature, mild-to-moderate in degree, occur early after initiation of treatment, often resolve spontaneously with continued use, and generally resolve after discontinuation of use. Among the reported adverse effects, two distinct manifestations of worsened erythema have been described. Brimonidine gel can be integrated into a treatment regimen along with concomitant therapies for facial papules and pustules with no increased risk of adverse events with combination therapy. Education about optimal application methods, setting reasonable expectations for treatment, and minimizing inflammation are important factors for the successful use of brimonidine

  14. Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response.

    Directory of Open Access Journals (Sweden)

    Ramesh K Wali

    Full Text Available Head and neck squamous cell carcinoma (HNSCC is a major cause of morbidity and mortality underscoring the need for safe and effective chemopreventive strategies. Targeting epidermal growth factor receptor (EGFR is attractive in that it is an early critical event in HNSCC pathogenesis. However, current agents lack efficacy or have unacceptable toxicity. Several groups have demonstrated that the over-the-counter medication, polyethylene glycol (PEG has remarkable chemopreventive efficacy against colon carcinogenesis. Importantly, we reported that this effect is mediated through EGFR internalization/degradation. In the current study, we investigated the chemopreventive efficacy of this agent against HNSCC, using both the well validated animal model 4-NQO (4-nitroquinoline 1-oxide rat model and cell culture with the human HNSCC cell line SCC-25. We demonstrated that daily topical application of 10% PEG-8000 in the oral cavity (tongue and cavity wall post 4NQO initiation resulted in a significant reduction in tumor burden (both, tumor size and tumors/tumor bearing rat without any evidence of toxicity. Immunohistochemical studies depicted decreased proliferation (number of Ki67-positive cells and reduced expression of EGFR and its downstream effectors cyclin D1 in the tongue mucosa of 4NQO-rats treated with PEG. We showed that EGFR was also markedly downregulated in SCC-25 cells by PEG-8000 with a concomitant induction of G1-S phase cell-cycle arrest, which was potentially mediated through upregulated p21(cip1/waf1. In conclusion, we demonstrate, for the first time, that PEG has promising efficacy and safety as a chemopreventive efficacy against oral carcinogenesis.

  15. Development of water-soluble polyanionic carbosilane dendrimers as novel and highly potent topical anti-HIV-2 microbicides

    Science.gov (United States)

    Briz, Verónica; Sepúlveda-Crespo, Daniel; Diniz, Ana Rita; Borrego, Pedro; Rodes, Berta; de La Mata, Francisco Javier; Gómez, Rafael; Taveira, Nuno; Muñoz-Fernández, Mª Ángeles

    2015-08-01

    The development of topical microbicide formulations for vaginal delivery to prevent HIV-2 sexual transmission is urgently needed. Second- and third-generation polyanionic carbosilane dendrimers with a silicon atom core and 16 sulfonate (G2-S16), napthylsulfonate (G2-NS16) and sulphate (G3-Sh16) end-groups have shown potent and broad-spectrum anti-HIV-1 activity. However, their antiviral activity against HIV-2 and mode of action have not been probed. Cytotoxicity, anti-HIV-2, anti-sperm and antimicrobial activities of dendrimers were determined. Analysis of combined effects of triple combinations with tenofovir and raltegravir was performed by using CalcuSyn software. We also assessed the mode of antiviral action on the inhibition of HIV-2 infection through a panel of different in vitro antiviral assays: attachment, internalization in PBMCs, inactivation and cell-based fusion. Vaginal irritation and histological analysis in female BALB/c mice were evaluated. Our results suggest that G2-S16, G2-NS16 and G3-Sh16 exert anti-HIV-2 activity at an early stage of viral replication inactivating the virus, inhibiting cell-to-cell HIV-2 transmission, and blocking the binding of gp120 to CD4, and the HIV-2 entry. Triple combinations with tenofovir and raltegravir increased the anti-HIV-2 activity, consistent with synergistic interactions (CIwt: 0.33-0.66). No vaginal irritation was detected in BALB/c mice after two consecutive applications for 2 days with 3% G2-S16. Our results have clearly shown that G2-S16, G2-NS16 and G3-Sh16 have high potency against HIV-2 infection. The modes of action confirm their multifactorial and non-specific ability, suggesting that these dendrimers deserve further studies as potential candidate microbicides to prevent vaginal/rectal HIV-1/HIV-2 transmission in humans.

  16. The cartoon in doctor-patient communication. Further study of the Arthritis and Rheumatism Council handbook on gout.

    Science.gov (United States)

    Moll, J M; Wright, V; Jeffrey, M R; Goode, J D; Humberstone, P M

    1977-06-01

    A sample of 50 consecutive patients with gout was tested by means of a multiple-choice knowledge-testing questionnaire based on the Arthritis and Rheumatism Council's Gout: A Handbook for Patients. Patients were divided into two groups: (a) those tested with an illustrated booklet containing 89 cartoons, and (b) those tested with an unillustrated booklet with text exactly the same as in the illustrated booklet. No significant difference was observed in either the overall test scores between the two groups or between individual question scores. It was concluded that increasing the number of illustrations in the Arthritis and Rheumatism Council's handbook on gout had not significantly increased the value of this material as a communication aid. Certain sources of error have been discussed including the possibility of an 'interest factor' due to the inevitable interest patients have in reading about their own disease, and also the possibility that technical factors to do with page layout and picture/text imbalance might be responsible for failing to show differences between the two groups.

  17. Listening comprehension for sentences: the accessibility of referents for pronouns as a function of age, topic continuity, and pronoun emphasis.

    Science.gov (United States)

    Kertoy, M K

    1991-12-01

    An auditory comprehension task was employed to determine how subjects (20 first graders, 20 fifth graders, and 20 adults) use topic continuity and contrastive emphasis in the assignment of referents for pronouns in sentences. Significant differences in performance for emphasized and unemphasized pronouns were found suggesting that subjects used contrastive emphasis when assigning referents for pronouns. Fifth graders overused the cue of topic continuity in assigning referents for emphasized pronouns. This effect has not been shown previously in studies of children's understanding of pronomial reference. An interaction between age and pronoun emphasis was also significant. This interaction suggests that developmental changes continued to take place in the learning of cues for resolving pronouns by school age children. PMID:1770333

  18. Concept mapping as a method to teach an evidence-based educated medical topic: a comparative study in medical students

    OpenAIRE

    Saeidifard, Farzane; Heidari, Kazem; Foroughi, Moein; Soltani, Akbar

    2014-01-01

    Background The objective of this study was to compare concept mapping with lecture-based method in teaching of evidence based educated topic to medical students. Methods This randomized controlled trial was carried out on medical students during sixth year of 7-year MD curriculum clerkship phase. Cluster randomization was used to divide students into intervention and control groups. Both groups, at the beginning, were taught “Diabetic Ketoacidosis” (DKA) using evidence-based tool named Critic...

  19. Solid Lipid Nanoparticles Loaded with Retinoic Acid and Lauric Acid as an Alternative for Topical Treatment of Acne Vulgaris.

    Science.gov (United States)

    Silva, Elton Luiz; Carneiro, Guilherme; De Araújo, Lidiane Advíncula; Trindade, Mariana de Jesus Vaz; Yoshida, Maria Irene; Oréfice, Rodrigo Lambert; Farias, Luis de Macêdo; De Carvalho, Maria Auxiliadora Roque; Dos Santos, Simone Gonçalves; Goulart, Gisele Assis Castro; Alves, Ricardo José; Ferreira, Lucas Antônio Miranda

    2015-01-01

    Topical therapy is the first choice for the treatment of mild to moderate acne and all-trans retinoic acid is one of the most used drugs. The combination of retinoids and antimicrobials is an innovative approach for acne therapy. Recently, lauric acid, a saturated fatty acid, has shown strong antimicrobial activity against Propionibacterium acnes. However, topical application of retinoic acid is followed by high incidence of side-effects, including erythema and irritation. Solid lipid nanoparticles represent an alternative to overcome these side-effects. This work aims to develop solid lipid nanoparticles loaded with retinoic acid and lauric acid and evaluate their antibacterial activity. The influence of lipophilic stearylamine on the characteristics of solid lipid nanoparticles was investigated. Solid lipid nanoparticles were characterized for size, zeta potential, encapsulation efficiency, differential scanning calorimetry and X-ray diffraction. The in vitro inhibitory activity of retinoic acid-lauric acid-loaded solid lipid nanoparticles was evaluated against Propionibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis. High encapsulation efficiency was obtained at initial time (94 ± 7% and 100 ± 4% for retinoic acid and lauric acid, respectively) and it was demonstrated that lauric acid-loaded-solid lipid nanoparticles provided the incorporation of retinoic acid. However, the presence of stearylamine is necessary to ensure stability of encapsulation. Moreover, retinoic acid-lauric acid-loaded solid lipid nanoparticles showed growth inhibitory activity against Staphylococcus epidermidis, Propionibacterium acnes and Staphylococcus aureus, representing an interesting alternative for the topical therapy of acne vulgaris. PMID:26328443

  20. Mechlorethamine Topical

    Science.gov (United States)

    ... used to treat early stage mycosis fungoides-type cutaneous T-cell lymphoma (CTCL; a cancer of the ... as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this ...

  1. Using Cartoons to Teach Corporate Social Responsibility: A Class Exercise

    Science.gov (United States)

    Mills, Adam J.; Robson, Karen; Pitt, Leyland F.

    2013-01-01

    Changing curriculum content requirements, based on shifting global perspectives on corporate behavior and capitalism as well as business school accreditation requirements, mean that many marketing instructors have attempted to introduce discussions of organizational ethics, corporate social responsibility, and corporate governance into their…

  2. Autonomy, Respect, and Arrogance in the Danish Cartoon Controversy

    DEFF Research Database (Denmark)

    Rostbøll, Christian F.

    2009-01-01

    complex than often posited. Particularly, it asks whether the autonomy defense of freedom of expression encourages disrespect for religious feelings. Autonomy leads to disrespect for diversity only when it is understood as a character ideal that must be promoted as an end in itself. If it by contrast...... is understood as something we should presume everyone possesses, it provides a strong basis for equal respect among people from diverse cultures. A Kantian conception of autonomy can justify the right to freedom of expression while it at the same time requires that we in the exercise of freedom of expression...

  3. Engaging Children through the Use of Cartoons and Comics

    Science.gov (United States)

    Weitkamp, Emma; Featherstone, Helen

    2010-01-01

    ScienceComics project originally involved a set of theatre performances that sought to highlight the importance of materials by exploring what happens when one uses the "wrong" material. As part of this early work, two plays were created that featured a young alien girl, called Selenia, who could change materials. In this article, the authors…

  4. Cartooning Humor: How Arabs are Laughably Derided in Animations

    Directory of Open Access Journals (Sweden)

    Mohamed Belamghari

    2015-12-01

    Full Text Available Some animated movies use humor to capture the full attention of its audience. In so doing, the movie’s messages have become a great concern for many theorists and critics by virtue of the idea that a movie can be a repository of ideologies meant to construct a certain type of easy-going and noncritical audience. This paper, therefore, takes the example of Max Fleischer’s Popeye the Sailor Meets Ali Baba and his Forty Thieves (1937 and Robert Clampett’s Ali Baba Bound (1941 as its case studies aiming at spotting the different manifestations of humor, taking Arabs as its subject-matter, becoming a leaked ideology and taming the discourse that is amplified, manipulated, and delivered to the Western public in unwarrantable ways compared to the imagery of Westerners.

  5. Topics in Physical Mathematics

    CERN Document Server

    Marathe, Kishore

    2010-01-01

    This title adopts the view that physics is the primary driving force behind a number of developments in mathematics. Previously, science and mathematics were part of natural philosophy and many mathematical theories arose as a result of trying to understand natural phenomena. This situation changed at the beginning of last century as science and mathematics diverged. These two fields are collaborating once again; 'Topics in Mathematical Physics' takes the reader through this journey. The author discusses topics where the interaction of physical and mathematical theories has led to new points o

  6. A cartoon-assisted proof of Sarkowskii's theorem

    Science.gov (United States)

    Kaplan, Harvey

    1987-11-01

    Much of the present article serves as an introduction to a set of ideas familiar in dynamical systems theory. No familiarity with these ideas is assumed on the part of the reader. The ideas are then combined in simple, geometric arguments to prove Sarkowskii's theorem. This theorem is important in the study of one-dimensional, deterministic, dissipative dynamical systems. It provides a unified framework for the occurrences of both orderly and chaotic motions. The relationship of the mathematical models discussed here to real physical and biological systems is discussed briefly and the reader is referred to the literature for descriptions of diverse, beautiful, relevant experiments.

  7. Land use and cover change as an overarching topic in the Dutch National Research Programme on Global Air Pollution and Climate Change : issues for implementation

    NARCIS (Netherlands)

    Fresco, L.O.; Berg, van den M.M.; Zeijl-Rozema, van A.E.

    1996-01-01

    The integration study 'Land Use and Cover Change as an overarching topic in the Dutch National Research Programme on Global Air Pollution and Climate Change (NRP)' aims at identifying research fields in which the NRP can contribute most effectively to the international scientific know-how

  8. Using Laboratory Activities Enhanced with Concept Cartoons to Support Progression in Students' Understanding of Acid-Base Concepts

    Science.gov (United States)

    Ozmen, Haluk; Demircioglu, Gokhan; Burhan, Yasemin; Naseriazar, Akbar; Demircioglu, Hulya

    2012-01-01

    The aim of this study is to examine the effectiveness of an intervention based on a series of laboratory activities enhanced with concept cartoons. The purpose of the intervention was to enhance students' understanding of acid-base chemistry for eight grade students' from two classes in a Turkish primary school. A pretest-posttest non-equivalent…

  9. Reaction Time of Facial Affect Recognition in Asperger's Disorder for Cartoon and Real, Static and Moving Faces

    Science.gov (United States)

    Miyahara, Motohide; Bray, Anne; Tsujii, Masatsugu; Fujita, Chikako; Sugiyama, Toshiro

    2007-01-01

    This study used a choice reaction-time paradigm to test the perceived impairment of facial affect recognition in Asperger's disorder. Twenty teenagers with Asperger's disorder and 20 controls were compared with respect to the latency and accuracy of response to happy or disgusted facial expressions, presented in cartoon or real images and in…

  10. A prospective comparison of topical feracrylum citrate versus adrenaline as haemostatic agent in hypospadias surgery in children

    Directory of Open Access Journals (Sweden)

    Ashok Kumar Laddha

    2014-01-01

    Full Text Available Background: A comparative study of topical feracrylum citrate versus adrenaline to minimise haemorrhage-related complications in paediatric hypospadiac patients. Patients and Methods: A total of 108 consecutive paediatric hypospadiac patients (48 in the study group and 60 control - random allocation were studied. In the study group, 1% feracrylum citrate solution was used and adrenaline (1:100,000 in controls. Results: Among the study group, average number of blood-soaked gauge pieces were 2.95/patient, correlating with average intraoperative blood loss of 14.74 ml. In controls, average blood-soaked gauge pieces were 4.83/patient corresponding to an average blood loss of 24.13 ml. The average amount of blood loss during surgery in the <5 years was 13.70 ml/patient in the feracrylum group, while the same in the adrenaline group was 23.45 ml. Average duration of surgery was 79 min in the study group, while the same in controls was 94 min/patient. Average number of cauterisations was 0.255/patient in the study group and 0.583/patient among controls. Postoperative haematoma was seen in 8% study group compared with 18% controls. Wound oedema appeared in 4.17% study group and 11.67% controls. Postoperative complications were higher among controls. Conclusions: Feracrylum is more efficient and safer topical haemostatic agent than adrenaline. It reduced the frequency of cauterisation and tissue damage, intraoperative blood loss, and postoperative complications.

  11. Sombras literárias: a fotonovela e a produção cultural Literary shadows: the strip cartoon and cultural production

    Directory of Open Access Journals (Sweden)

    André Luiz Joanilho

    2008-01-01

    Full Text Available As fotonovelas tiveram um mercado cativo por mais de 25 anos no Brasil, e milhões de leitores consumiram ansiosamente histórias publicadas em revistas com larga circulação nacional. No entanto, foram ignoradas quase que completamente por críticos e estudiosos e consideradas um subgênero da literatura. Seus leitores foram marcados, entre outros aspectos, como de baixa formação cultural e possuidores de parcos rendimentos. Entretanto, seria possível para o historiador não reconhecer a leitura de fotonovelas como uma manifestação de práticas sociais? Poderia a cultura de massa ter criado um conjunto enorme de leitores sem face e sem gosto? Estas questões nos permitem pensar as representações sociais femininas no Brasil e as práticas de leitura das décadas de 1950 e 1960.Strip cartoons had a captive market for more than twenty years in Brazil and millions of readers eagerly consumed stories published in magazines with national circulation. Nevertheless this type of vehicle was almost completely ignored by scholars and considered a sub-genre of literature, and its reading public considered as of low cultural capacity and low income level. However, is it possible for the historian not to recognize cartoon strips as a social practice? Could mass culture have created an enormous number of readers without face and taste? These questions bring to the fore the feminist social movements in Brazil and the reading practices of the fifties and sixties.

  12. Soma maden faciası karikatürlerinin değerlendirilmesi: Salih Memecan, Mehmet Çağçağ, Osman Turhan ve Behiç Ak örnekleri (Evaluation of mine disaster soma cartoon with samples:.........)

    OpenAIRE

    TÜRTEN, Elif

    2015-01-01

    The concept of cartoon is defined many different kinds in the literature. The most common of these definitions is the art of making humor. Cartoon, constitutes the essence of a situation, targeting universal one and represents the schematic reality. Less verbally or only offered to the reader with a line cartoon refers to urge people to laugh. Cartoon can easily convince to affect people. Therefore; publications, have begun to use cartoons in their publications frequently. In our study, carto...

  13. Topical ketoprofen patch.

    Science.gov (United States)

    Mazières, Bernard

    2005-01-01

    Although oral nonsteroidal anti-inflammatory drugs (NSAIDs) are effective in the treatment of a variety of acute and chronic pain conditions, their use may be associated with serious systemic adverse effects, particularly gastrointestinal disorders. In order to minimise the incidence of systemic events related to such agents, topical NSAIDs have been developed. Topical NSAIDs, applied as gels, creams or sprays, penetrate the skin, subcutaneous fatty tissue and muscle in amounts that are sufficient to exert a therapeutic effect on peripheral and central mechanisms in the absence of high plasma concentrations. Data indicate that topical NSAIDs are effective at relieving pain in a number of acute and chronic pain indications. This review article discusses the pharmacokinetics, efficacy and tolerability of a new formulation of ketoprofen available as a topical patch. The topical patch containing ketoprofen 100mg as the active principle has been developed using a novel delivery system that dispenses therapeutic doses of the drug directly to the site of injury. Pharmacokinetic data indicate that although plasma levels of ketoprofen are higher when the drug is administered as a patch versus a gel, the total systemic bioavailability of ketoprofen 100 mg administered via a patch is no more than 10% of that reported for ketoprofen 100 mg administered orally. Because the patch facilitates ketoprofen delivery over a 24-hour period, the drug remains continually present in the tissue subjacent to the site of application. High tissue but low plasma ketoprofen concentrations mean that while tissue concentrations are high enough to exert a therapeutic effect, plasma concentrations remain low enough to not result in systemic adverse events caused by elevated serum NSAID levels. Phase III clinical trials in patients with non-articular rheumatism and traumatic painful soft tissue injuries showed that the topical ketoprofen patch was significantly more effective than placebo at

  14. Cartoons, movies

    DEFF Research Database (Denmark)

    Sheikh, Mona Kanwal; Gad, Ulrik Pram

    Dutch MP Geert Wilders has declared that he will soon release a 15 minutes movie called "Fitna" to make his criticism of the Quran more trenchant. "Fitna" is likely to meet harsh reactions. Both because the modus operandi of Wilders falls nicely into what have become a specific genre of political...... targeted at the provoker. It seems like there is a pattern in these self-reinforcing cycles of conflict that needs responsible reconsideration: Staunch defence of principles come in the way of dialogue and diplomacy....

  15. A Zuni Artist looks at Frank Hamilton Cushing: Cartoons by Phil Hughte, Pueblo of Zuni Arts and Crafts, Zuni, New Mexico

    Directory of Open Access Journals (Sweden)

    Douglas R. Givens

    1996-05-01

    Full Text Available This book is a very unique look into the legacy of Frank Hamilton Cushing at Zuni and his influence on the Zuni people by the Zuni cartoonist Phil Hughte. This volume of Hughte's cartoons depicts Cushing at various periods and important moments of his career at Zuni. Although Hughte's cartoons selected Cushing moments at Zuni require no words to express Cushing's influence on the pueblo, Hughte provides captions to each of his cartoons designed to explain what Cushing was doing to the reader who is not intimately knowledgeable about Cushing's work.

  16. 浅析中国民间图案在动画设计中的应用%The Application of Chinese Folk Patterns in Cartoon Design

    Institute of Scientific and Technical Information of China (English)

    赵云

    2014-01-01

    The Chinese nation has a long history with 5 ,000 years'civilization .Her traditional culture is the spiritual wealth which gets the nation to stand out all over the world and the strong power which makes the nation's culture passed on and develop as well .Among the excellent culture ,China's folk patterns , w hich are considered to be essential cultural heritage ,are of important components .It is urgent for the cartoon designers to place an emphasis on how to discover and to make full use of them .%阐述了中国民间图案的特点,表达方法和种类,并着重分析了中国民间图案在动画角色和场景中的应用。

  17. Historical Topics in Algebra.

    Science.gov (United States)

    National Council of Teachers of Mathematics, Inc., Reston, VA.

    This is a reprint of the historical capsules dealing with algebra from the 31st Yearbook of NCTM,"Historical Topics for the Mathematics Classroom." Included are such themes as the change from a geometric to an algebraic solution of problems, the development of algebraic symbolism, the algebraic contributions of different countries, the origin and…

  18. Transportation: Topic Paper E.

    Science.gov (United States)

    National Council on the Handicapped, Washington, DC.

    As one of a series of topic papers assessing federal laws and programs affecting persons with disabilities, this paper reviews the issue of transportation services. In the area of urban mass transit, four relevant pieces of legislation and public transportation accessibility regulations are cited, and cost issues are explored. Paratransit systems,…

  19. Selected topics in magnetism

    CERN Document Server

    Gupta, L C

    1993-01-01

    Part of the ""Frontiers in Solid State Sciences"" series, this volume presents essays on such topics as spin fluctuations in Heisenberg magnets, quenching of spin fluctuations by high magnetic fields, and kondo effect and heavy fermions in rare earths amongst others.

  20. A Preliminary, Open Label, Single-arm Study of Calcipotriene/Betamethasone Topical Suspension as a Supplement to Non-biologic Systemic Therapy for Psoriasis

    Science.gov (United States)

    Kupetsky, Erine; Houston, Neil A.M.

    2016-01-01

    Background: Calcipotriene/betamethasone topical suspension is a topical therapy that is often used as monotherapy as a first-line treatment for plaque psoriasis. The objective of this preliminary, open label, single arm study was to determine the efficacy of adding a topical suspension to a traditional systemic therapy for psoriasis, either methotrexate or acitretin. Methods: In this exploratory study, eight patients with chronic plaque psoriasis who were on stable methotrexate or acitretin treatment without clearance were treated with once-daily calcipotriene/betamethasone topical suspension. Subjects completed five study visits over 12 weeks. Primary outcome measure was improvement of two or more points in Investigator Global Assessment. Secondary endpoints included change in Body Surface Area, Dermatology Life Quality Index, and Patient’s Global Assessment from baseline to Week 12. Results: Overall, the median decrease in Investigator Global Assessment over 12 weeks was 1.5 points, with 50 percent of subjects experiencing a drop of two or more points in Investigator Global Assessment. All eight subjects had a reduction in Body Surface Area and Patient’s Global Assessment. There was a mean decrease in Dermatology Life Quality Index score of 78.9 percent, showing improved patient quality of life. In addition, all patients tolerated the treatment well and 6 of 8 patients had improved satisfaction level with their treatment by the end of the study. Conclusion: The topical suspension was effective and well-tolerated in conjunction with stable methotrexate or acitretin treatment in all eight patients in this study. These results support the feasibility of a larger scale study to further investigate the efficacy of these treatment combinations. The trial is registered at ClinicalTrials.gov, number NCT01761019. PMID:27462386

  1. Discovering health topics in social media using topic models.

    Directory of Open Access Journals (Sweden)

    Michael J Paul

    Full Text Available By aggregating self-reported health statuses across millions of users, we seek to characterize the variety of health information discussed in Twitter. We describe a topic modeling framework for discovering health topics in Twitter, a social media website. This is an exploratory approach with the goal of understanding what health topics are commonly discussed in social media. This paper describes in detail a statistical topic model created for this purpose, the Ailment Topic Aspect Model (ATAM, as well as our system for filtering general Twitter data based on health keywords and supervised classification. We show how ATAM and other topic models can automatically infer health topics in 144 million Twitter messages from 2011 to 2013. ATAM discovered 13 coherent clusters of Twitter messages, some of which correlate with seasonal influenza (r = 0.689 and allergies (r = 0.810 temporal surveillance data, as well as exercise (r =  .534 and obesity (r =  -.631 related geographic survey data in the United States. These results demonstrate that it is possible to automatically discover topics that attain statistically significant correlations with ground truth data, despite using minimal human supervision and no historical data to train the model, in contrast to prior work. Additionally, these results demonstrate that a single general-purpose model can identify many different health topics in social media.

  2. Differential Topic Models.

    Science.gov (United States)

    Chen, Changyou; Buntine, Wray; Ding, Nan; Xie, Lexing; Du, Lan

    2015-02-01

    In applications we may want to compare different document collections: they could have shared content but also different and unique aspects in particular collections. This task has been called comparative text mining or cross-collection modeling. We present a differential topic model for this application that models both topic differences and similarities. For this we use hierarchical Bayesian nonparametric models. Moreover, we found it was important to properly model power-law phenomena in topic-word distributions and thus we used the full Pitman-Yor process rather than just a Dirichlet process. Furthermore, we propose the transformed Pitman-Yor process (TPYP) to incorporate prior knowledge such as vocabulary variations in different collections into the model. To deal with the non-conjugate issue between model prior and likelihood in the TPYP, we thus propose an efficient sampling algorithm using a data augmentation technique based on the multinomial theorem. Experimental results show the model discovers interesting aspects of different collections. We also show the proposed MCMC based algorithm achieves a dramatically reduced test perplexity compared to some existing topic models. Finally, we show our model outperforms the state-of-the-art for document classification/ideology prediction on a number of text collections. PMID:26353238

  3. Alkyl polyglucoside-stabilized emulsion as a prospective vehicle for Usnea barbata CO2-supercritical extract: Assessing stability, safety and efficiency of a topical formulation

    Directory of Open Access Journals (Sweden)

    Žugić Ana R.

    2015-01-01

    Full Text Available Antimicrobial activity of Usnea barbata especially against bacteria involved in pathogenesis of various skin conditions has been well documented in literature. Nevertheless, there are no papers dealing with formulation of its isolates into topical preparations for treatment of skin infections. In present study, alkyl polyglucoside (APG - based vehicle was developed as carrier of U. barbata CO2-supercritical extract (U-SE that demonstrated the best antimicrobial potential in preliminary screening. For comparison, chosen extract in the same concentration and using the same procedure was incorporated into a pharmacopoeial vehicle. Comparative evaluation of physicochemical stability, efficiency and safety proved APG-based vehicle to possess certain preferential features as carrier of U-SE compared to the reference one, composing a topical formulation with potential clinical relevance in treatment of skin infections. [Projekat Ministarstva nauke Republike Srbije, br. III45017 i br. TR34031

  4. The influence of cartoons on attitudes to science and to being a scientist - doi: 10.4025/actascilangcult.v35i2.17551

    Directory of Open Access Journals (Sweden)

    Paula Cavalcante Monteiro

    2013-05-01

    Full Text Available Television is a powerful vehicle of mass communication and several cartoons, specifically made for children and adolescents, have ‘scientific’ themes. Preteens and teens devote many hours in front of TV, attracted by cartoons, some of which portray, in a caricature manner, scientists at work. Current paper investigates the effect the concepts of science transmitted by the cartoon ‘Jimmy Neutron’ have on adolescents. A group of 31 adolescents of the 9th grade of the junior school were invited to watch three episodes of the ‘Jimmy Neutron’ cartoon. After the sessions, they answered a questionnaire and were interviewed on their perceptions of Science and scientists. Their answers were analyzed by Discourse Textual Analysis. Results show that they most have misconceptions on Science and on scientists and they presume that scientists have a very solitary and uninterested life solely dedicated in investing new devises.

  5. Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - Part 3: Mentha × piperita - Solanum dulcamara.

    Science.gov (United States)

    Calapai, Gioacchino; Minciullo, Paola L; Miroddi, Marco; Chinou, Ioanna; Gangemi, Sebastiano; Schmidt, Richard J

    2016-03-01

    This review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph - now (since 2015)(†) called a European Union herbal monograph - has been produced. Part 3: Mentha × piperita L.-Solanum dulcamara L.

  6. Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products - Part 3: Mentha × piperita - Solanum dulcamara.

    Science.gov (United States)

    Calapai, Gioacchino; Minciullo, Paola L; Miroddi, Marco; Chinou, Ioanna; Gangemi, Sebastiano; Schmidt, Richard J

    2016-03-01

    This review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph - now (since 2015)(†) called a European Union herbal monograph - has been produced. Part 3: Mentha × piperita L.-Solanum dulcamara L. PMID:26563681

  7. Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques.

    Science.gov (United States)

    Pan, H J; Wilding, G; Uno, H; Inui, S; Goldsmith, L; Messing, E; Chang, C

    1998-08-01

    The effect of androgen receptor transcriptional activation by RU58841, a nonsteroidal anti-androgen, was studied in the human prostate cancer PC3 cell line by cotransfection with wild-type androgen receptor (wt AR) and an androgen-responsive reporter (MMTV-ARE-CAT) construct. Anti-and rogens, hydroxyflutamide, and Casodex, and the antiestrogen, genistein, were studied in parallel for comparison with RU58841. The wt AR was activated only by the androgen dihydrotestosterone (DHT). Neither the anti-androgens nor antiestrogen can enhance AR transcriptional activity at 10(-11)-10(-7)M in PC3 cells. Hydroxyflutamide, RU58841, and Casodex, but not genistein, displayed competitively suppressive effects on DHT activation of wt AR. The potency of RU58841 was comparable to that of hydroxyflutamide. From this result, topical application of RU58841, which is considered to be a potential therapy for skin diseases, may induce systemic side effects. However, RU58841, on topical application, revealed a potent increase in density, thickening, and length of hair in the macaque model of androgenetic alopecia, whereas no systemic effects were detected. Together our results suggest that RU58841 may have potent antagonism to the wt AR and could be considered as a topically applied active anti-androgen for the treatment of androgen-dependent skin disorders, such as acne, androgenetic alopecia, and hirsutism.

  8. A Brief Talk on Commercial Value of Cartoon Advertisement%浅谈动漫在电视广告中的商业价值

    Institute of Scientific and Technical Information of China (English)

    冯琨

    2012-01-01

    动漫广告是将动漫形象和电视广告采用多媒体技术合成产生的新生事物.本文结合经典的动漫广告案例,分析了动漫广告带来巨大商机的原因,认为动漫丰富的画面语言表达易吸引受众注意,从而引发潜在的消费力.同时,还对动漫在电视广告的应用前景作了展望,指出动漫广告与数字媒体的结合将产生巨大的商业市场价值.%Cartoon advertisement is a new matter via combining cartoon images and television advertisement by means of multimedia synthetic technique. Based on the classic cartoon advertisement cases, this paper illuminates the reasons for enormous business opportunity promoted by cartoon advertisement, it is revealed that the rich menu language attracts the audience's attention, which further triggers their potential consuming capacity. Moreover, the commercial foreground of cartoon advertisement is prospected in this paper. It is indicated that the combination of cartoon advertisement and digital media would produce vast commercial market value.

  9. An Analysis on Effects of the Bad Cutscene of Children Cartoons on Moral Education of Children%儿童动画片中的不良画面对儿童德育教育的影响探析

    Institute of Scientific and Technical Information of China (English)

    杨红慧

    2016-01-01

    In recent years,with a lot of bad cutscene in cartoons,such as, fighting,violence,vulgar, boring ones,have subtly negative impacts on children. By analyzing the main disadvantages and moral hazard to children of the bad cutscene in present popular children's cartoons to call for the joint efforts of whole society to strengthen the supervision of the quality of children's cartoons and eliminate the negative impacts on children physical and mental health. Only by these ways can make children grow up healthily and happily in a friendly,love,civilized,and full of knowledge and power environment.%近年来,由于一些儿童动画片中充斥着大量打斗、暴力、恶俗、无聊等画面,已潜移默化地对儿童产生了消极影响。通过对当下热播的儿童动画片为例,对其中出现的不良画面进行剖析,从存在的主要弊端和对儿童思想品德危害表现,呼吁全社会共同努力,加强儿童动画片的质量监管,消除动画片对儿童身心健康的负面影响,使儿童能在充满友善、爱、文明和知识的正能量环境中健康、快乐的成长。

  10. Linguistic Extensions of Topic Models

    Science.gov (United States)

    Boyd-Graber, Jordan

    2010-01-01

    Topic models like latent Dirichlet allocation (LDA) provide a framework for analyzing large datasets where observations are collected into groups. Although topic modeling has been fruitfully applied to problems social science, biology, and computer vision, it has been most widely used to model datasets where documents are modeled as exchangeable…

  11. Advancements in Topical Antifungal Vehicles.

    Science.gov (United States)

    Kircik, Leon H

    2016-02-01

    The primary treatment for superficial fungal infections is antifungal topical formulations, and allylamines and azoles represent the two major classes of topical formulations that are used to treat these infections. The stratum corneum (SC) is composed of keratinocytes that are surrounded by a matrix of lipids. The efficacy of topically applied formulations depends on their ability to penetrate this lipid matrix, and the vehicle plays an integral role in the penetration of active molecule into skin. There are several challenges to formulating topical drugs, which include the biotransformation of the active molecules as they pass through the SC and the physical changes that occur to the vehicle itself when it is applied to the skin. This article will review current and emerging topical antifungal vehicles. PMID:26885798

  12. Topical or oral administration with an extract of Polypodium leucotomos prevents acute sunburn and psoralen-induced phototoxic reactions as well as depletion of Langerhans cells in human skin

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, S.; Pathak, M.A.; Fitzpatrick, T.B. [Massachusetts General Hospital, Harvard Medical School, Dept. of Dermatology, Boston, MA (United States); Cuevas, J. [Hospital Universitario de Guadalajara, Dept. of Pathology, Guadalajara (Spain); Villarrubia, V.G. [I.F. Cantabria SA, Medical Dept., Immunology Sect., Madrid (Spain)

    1997-12-31

    Sunburn, immune suppression, photo-aging, and skin cancers result from uncontrolled overexposure of human skin to solar ultraviolet radiation (UVR). Preventive measures, including photo-protection, are helpful and can be achieved by topical sun-screening agents. Polypodium leucotomos (PL) has been used for the treatment of inflammatory diseases and has shown some in vitro and in vivo immunomodulating properties. Its beneficial photo-protective effects in the treatment of vitiligo and its antioxidant properties encouraged us to evaluate in vivo the potentially useful photo-protective property of natural extract of PL after topical application or oral ingestion. Twenty-one healthy volunteers [either untreated or treated with oral psoralens (8-MOP or 5-MOP)] were enrolled in this study and exposed to solar radiation for evaluation of the following clinical parameters: immediate pigment darkening (IPD), minimal erythema dose (MED), minimal melanogenic dose (MMD), and minimal phototoxic dose (MPD) before and after topical or oral administration of PL. Immunohistochemical assessment of CD1a-expressing epidermal cells were also performed. PL was found to be photo-protective after topical application as well as oral administration. PL increased UV dose required for IPD (P<0.01), MED (P<0.001) and MPD (P<0.001). After oral administration of PL, MED increased 2.,8{+-}0.59 times and MPD increased 2.75{+-}0.5 and 6.8{+-}1.3 times depending upon the type of psoralen used. Immunohistochemical study revealed photo-protection of Langherhans cells by oral as well as topical PL. The observed photo-protective activities of oral or topical PL reveal a new avenue in examining the potentially useful field of systemic photo-protection and suggests that PL can be used as adjunct treatment and can make photochemotherapy and phototherapy possibly safe and effective when the control of cutaneous phototoxicity to PUVA or UVB is a limiting factor in such photo-therapies. (au). 50 refs.

  13. A Study on Parents' Response to Children's Love for Hero Type Cartoons and Suggestions%对家长就幼儿喜爱英雄型动画片所作出的回应行为的研究及相关建议

    Institute of Scientific and Technical Information of China (English)

    郝红翠

    2012-01-01

    本研究以日本英雄型动画片《奥特曼》为例,通过问卷调查和访谈了解家长对幼儿喜爱这类英雄型动画片所作出的回应行为,并分析家长的教养观念对其回应行为的影响。在此基础上,研究者提出了相关建议。%This study, using questionnaires and interviews, investigates how parents respond to their children's love for the hero type cartoons such as Japanese cartoon Ultraman, analyzes the influence their education opinions may have on their response. Based on these, the researcher puts forward some related suggestions.

  14. Topical rapamycin as a treatment for fibrofolliculomas in Birt-Hogg-Dube syndrome: a double-blind placebo-controlled randomized split-face trial.

    Directory of Open Access Journals (Sweden)

    Lieke M C Gijezen

    Full Text Available BACKGROUND: Birt-Hogg-Dubé syndrome (BHD is a rare autosomal dominant disorder characterised by the occurrence of benign, mostly facial, skin tumours called fibrofolliculomas, multiple lung cysts, spontaneous pneumothorax and an increased renal cancer risk. Current treatments for fibrofolliculomas have high rates of recurrence and carry a risk of complications. It would be desirable to have a treatment that could prevent fibrofolliculomas from growing. Animal models of BHD have previously shown deregulation of mammalian target of rapamycin (mTOR. Topical use of the mTOR inhibitor rapamycin is an effective treatment for the skin tumours (angiofibromas in tuberous sclerosis complex, which is also characterised by mTOR deregulation. In this study we aimed to determine if topical rapamycin is also an effective treatment for fibrofolliculomas in BHD. METHODS: We performed a double blinded, randomised, facial left-right controlled trial of topical rapamycin 0.1% versus placebo in 19 BHD patients. Trial duration was 6 months. The primary outcome was cosmetic improvement as measured by doctors and patients. Changes in fibrofolliculoma number and size were also measured, as was occurrence of side effects. RESULTS: No change in cosmetic status of fibrofolliculomas was reported in the majority of cases for the rapamycin treated (79% by doctors, 53% by patients as well as the placebo treated facial sides (both 74%. No significant differences between rapamycin and placebo treated facial halves were observed (p = 1.000 for doctors opinion, p = 0.344 for patients opinion. No significant difference in fibrofolliculoma number or change in size of the fibrofolliculomas was seen after 6 months. Side effects occurred more often after rapamycin treatment (68% of patients than after placebo (58% of patients; p = 0.625. A burning sensation, erythema, itching and dryness were most frequently reported. CONCLUSIONS: This study provides no evidence that

  15. Topical erythropoietin as a novel preventive and therapeutic agent in bisphosphonate-related osteonecrosis of the jaw

    Directory of Open Access Journals (Sweden)

    Pantea Nazeman

    2016-01-01

    Full Text Available Introduction: One of the most common side effects of bisphosphonate intake is osteonecrosis of the jaw (ONJ which may develop following dentoalveolar interventions. Despite the vast available protocols, there is no clear guideline in the management of this condition. In osteonecrosis, the number and proliferation of bone-forming cells as well as vascularity are disturbed. Erythropoietin (EPO is a hematopoietic hormone with angiogenic, osteogenic, and antiapoptotic properties. The Hypothesis: It is suggested to utilize poly lactic-co-glycolic acid hydrogel containing 1500-3000 IU/kg EPO following dentoalveolar surgery in samples receiving bisphosphonates as a preventive or therapeutic agent. Evaluation of the Hypothesis: Considering the pathophysiology of ONJ and therapeutic properties of EPO, it is assumed that EPO may be effective in treatment of ONJ. Furthermore, as a preventive measure, utilizing EPO following dentoalveolar surgery may be beneficial in the patients at risk of ONJ.

  16. SLN as a topical delivery system for Artemisia arborescens essential oil: In vitro antiviral activity and skin permeation study

    OpenAIRE

    Lai, Francesco; Sinico, Chiara; De Logu, Alessandro; Zaru, Marco; Müller, Rainer H.; Fadda, Anna M.

    2007-01-01

    The effect of SLN incorporation on transdermal delivery and in vitro antiherpetic activity of Artemisia arborescens essential oil was investigated. Two different SLN formulations were prepared using the hot – pressure homogenization technique, Compritol 888 ATO as lipid, and Poloxamer 188 and Miranol Ultra C32 as surfactants. Formulations were examined for their stability for two years by monitoring average size distribution and zeta potential values. The antiviral activity of free and SLN in...

  17. Clinical application of oral form of ANGIPARSTM and in combination with topical form as a new treatment for diabetic foot ulcers: A randomized clinical trial

    Directory of Open Access Journals (Sweden)

    Bahrami A

    2008-04-01

    Full Text Available ANGIPARSTM is a new herbal extract which has been produced in oral, topical, and intravenous forms. The present article contains preliminary results of the study which was planned to evaluate the efficacy and safety of orally applied ANGIPARSTM and to compare it with the combination of oral and topical forms and also with conventional therapy in patients with diabetic ulcers of the lower extremities."nTwenty one patients with diabetic foot ulcers were divided into 3 groups. The first group received 100 mg of oral ANGIPARSTM twice a day for 6 weeks in addition to conventional therapies. In the second group, ANGIPARSTM gel 3% was added to the oral form of the same product besides the conventional therapies for the same period of time. Finally, in the third group which was considered as control, only conventional therapies were performed. The patients were followed for 6 weeks. Parameters such as granulation tissue formation, skin epithelization, and wound surface areas changes were analyzed to determine the effectiveness of the compound in wounds healing. Furthermore, drug safety was assessed by monitoring adverse events and by clinical and laboratory evaluations."nThe study data showed significant differences between the intervention and control groups with respect to efficacy and tolerability. In each intervention group, primary wound healings occurred following 2 weeks. Complete wound healing which was greater than 70% improvement in wounds surface areas was achieved in 83% and 100% of group 1 and group 2 participants, respectively after 6 weeks. On the other hand, at the same period of time, only 22.2% of patients in control group revealed complete healing. Therefore, ANGIPARSTM had significant positive effect in increasing the incidence of complete wound closure compared with control group (p = 0.042. However, our evaluations indicated that adding topical treatment with 3% gel once a day to the oral therapy with the same product did not make

  18. Topics in Operator Theory

    CERN Document Server

    Ball, Joseph A; Helton, JWilliam; Rodman, Leiba; Spitkovsky, Iiya

    2010-01-01

    This is the first volume of a collection of original and review articles on recent advances and new directions in a multifaceted and interconnected area of mathematics and its applications. It encompasses many topics in theoretical developments in operator theory and its diverse applications in applied mathematics, physics, engineering, and other disciplines. The purpose is to bring in one volume many important original results of cutting edge research as well as authoritative review of recent achievements, challenges, and future directions in the area of operator theory and its applications.

  19. Topics in field theory

    CERN Document Server

    Karpilovsky, G

    1989-01-01

    This monograph gives a systematic account of certain important topics pertaining to field theory, including the central ideas, basic results and fundamental methods.Avoiding excessive technical detail, the book is intended for the student who has completed the equivalent of a standard first-year graduate algebra course. Thus it is assumed that the reader is familiar with basic ring-theoretic and group-theoretic concepts. A chapter on algebraic preliminaries is included, as well as a fairly large bibliography of works which are either directly relevant to the text or offer supplementary material of interest.

  20. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

    Science.gov (United States)

    Bozic, Mirjana; Man'ko, Margarita

    2009-09-01

    This topical issue of Physica Scripta collects selected peer-reviewed contributions based on invited and contributed talks and posters presented at the 15th Central European Workshop on Quantum Optics (CEWQO) which took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu). On behalf of the whole community took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu, cewqo08.phy.bg.ac.yu). On behalf of the whole community of the workshop, we thank the referees for their careful reading and useful suggestions which helped to improve all of the submitted papers. A brief description of CEWQO The Central European Workshop on Quantum Optics is a series of conferences started informally in Budapest in 1992. Sometimes small events transform into important conferences, as in the case of CEWQO. Professor Jozsef Janszky, from the Research Institute of Solid State Physics and Optics, is the founder of this series. Margarita Man'ko obtained the following information from Jozsef Janszky during her visit to Budapest, within the framework of cooperation between the Russian and Hungarian Academies of Sciences in 2005. He organized a small workshop on quantum optics in Budapest in 1992 with John Klauder as a main speaker. Then, bearing in mind that a year before Janszky himself was invited by Vladimir Buzek to give a seminar on the same topic in Bratislava, he decided to assign the name 'Central European Workshop on Quantum Optics', considering the seminar in Bratislava to be the first workshop and the one in Budapest the second. The third formal workshop took place in Bratislava in 1993 organized by Vladimir Buzek, then in 1994 (Budapest, by Jozsef Janszky), 1995 and 1996 (Budmerice, Slovakia, by Vladimir Buzek), 1997 (Prague, by Igor Jex), 1999 (Olomouc, Czech Republic, by Zdenek Hradil), 2000 (Balatonfüred, Hungary, by Jozsef Janszky ), 2001 (Prague, by Igor Jex), 2002 (Szeged, Hungary, by Mihaly Benedict), 2003 (Rostock,Germany, by Werner Vogel and

  1. SLN as a topical delivery system for Artemisia arborescens essential oil: In vitro antiviral activity and skin permeation study

    Science.gov (United States)

    Lai, Francesco; Sinico, Chiara; De Logu, Alessandro; Zaru, Marco; Müller, Rainer H; Fadda, Anna M

    2007-01-01

    The effect of SLN incorporation on transdermal delivery and in vitro antiherpetic activity of Artemisia arborescens essential oil was investigated. Two different SLN formulations were prepared using the hot – pressure homogenization technique, Compritol 888 ATO as lipid, and Poloxamer 188 and Miranol Ultra C32 as surfactants. Formulations were examined for their stability for two years by monitoring average size distribution and zeta potential values. The antiviral activity of free and SLN incorporated essential oil was tested in vitro against Herpes Simplex Virus-1 (HSV-1) by a quantitative tetrazolium-based colorimetric method (MTT), while the effects of essential oil incorporation into SLN on both the permeation through and the accumulation into the skin strata was investigated by using in vitro diffusion experiments through newborn pig skin and an almond oil Artemisia essential oil solution as a control. Results showed that both SLN formulations were able to entrap the essential oil in high yields and that the mean particle size increased only slightly after two years of storage, indicating a high physical stability. In vitro antiviral assays showed that SLN incorporation did not affect the essential oil antiherpetic activity. The in vitro skin permeation experiments demonstrated the capability of SLN of greatly improving the oil accumulation into the skin, while oil permeation occurred only when the oil was delivered from the control solution. PMID:18019840

  2. Topic Model for Graph Mining.

    Science.gov (United States)

    Xuan, Junyu; Lu, Jie; Zhang, Guangquan; Luo, Xiangfeng

    2015-12-01

    Graph mining has been a popular research area because of its numerous application scenarios. Many unstructured and structured data can be represented as graphs, such as, documents, chemical molecular structures, and images. However, an issue in relation to current research on graphs is that they cannot adequately discover the topics hidden in graph-structured data which can be beneficial for both the unsupervised learning and supervised learning of the graphs. Although topic models have proved to be very successful in discovering latent topics, the standard topic models cannot be directly applied to graph-structured data due to the "bag-of-word" assumption. In this paper, an innovative graph topic model (GTM) is proposed to address this issue, which uses Bernoulli distributions to model the edges between nodes in a graph. It can, therefore, make the edges in a graph contribute to latent topic discovery and further improve the accuracy of the supervised and unsupervised learning of graphs. The experimental results on two different types of graph datasets show that the proposed GTM outperforms the latent Dirichlet allocation on classification by using the unveiled topics of these two models to represent graphs. PMID:25616091

  3. Integrierter Sprach- und Sachunterricht im Spanischkurs fuer Fortgeschrittene am Beispiel des Themas "La Emigracion actual" (Integrated Instruction in Language and Realia in the Advanced Spanish Course, with, as an Example, the Topic "The Present Emigration")

    Science.gov (United States)

    Christ, Ingeborg

    1975-01-01

    Advanced-level Spanish courses often lead outside everyday situations. Text, topic, language content and skill orientation form a complex of conditions for advanced learning. Consequences of significance for the learning process are discussed, with the topic "la emigracion actual" ("the present emigration") as a base. (Text is in German.) (IFS/WGA)

  4. The future of topical analgesics.

    Science.gov (United States)

    Arnstein, Paul M

    2013-07-01

    Topically applied analgesic therapies have been used throughout history to treat a variety of patient conditions that present with pain. Before modem pharmaceuticals became readily available, mud-based emollients, salves, cold therapies, and other natural remedies were often used. Now we have effective therapies and are developing advanced topical analgesics as we learn more about the physiology and pathophysiology of pain. The use of topical analgesics may be associated with fewer patient systemic side effects than are seen with oral, parenteral, or transdermally administered agents, making the topical route of administration attractive to prescribers and patients. With further refinement of existing drugs and the development of novel agents, topical analgesics may offer relief for treating patient pain conditions that are currently challenging to treat, such as pain resulting from burns, wound debridement, and pressure ulcers. Recognizing the value of a multimodal approach, topical analgesics may offer a therapeutic option that can become part of a comprehensive treatment plan for the patient. With continued advancements in targeted drug-delivery systems, topical analgesics may be able to provide a method to prevent or reverse the phenomena of peripheral and central sensitization, or the neuroplastic changes believed to be responsible for the transition from acute to chronic pain states in patients. For those patients at risk for developing chronic pain states, such as complex regional pain syndrome, the combination of cutaneous stimulation (achieved through rubbing during application) and analgesic effects produced by the drug itself may prevent the disabling pain that often emerges during the subacute phase of disease. In summary, better utilization of currently available topical analgesics and continued research promise to ensure that topical analgesics are, and will continue to be, important tools in the treatment of patients with resistant pain. PMID

  5. Computational mediation as factor of motivation and meaningful learning in education of sciences of 9th grade: astronomy topics

    Science.gov (United States)

    Da Silva, F. M.; Furtado, W. W.

    2012-10-01

    The main purpose of this study was to analyze the contribution of using hypertext and pedagogic mediation in search of a Meaningful Learning Process in Sciences. We investigate the usage of hypertext in the teaching and learning methods of Astronomy modules. A survey was conducted with students from the 9th grade of Primary School of a public school in the city of Goiânia, Goiás in Brazil. We have analyzed the possibilities that hypermedia can offer in the teaching and learning process, using as reference David Ausubel's Theory of Meaningful Learning. The study was divided into four phases: application of an initial questionnaire on students, development of didactic material (hypertext), six classes held in a computer lab with the use of hypermedia and a final questionnaire applied in the lab after classes. This research indicated that the use of hypertext linked to pedagogical mediation processes is seen as a motivational tool and has potential to foster to Meaningful Learning.

  6. Temporary shelter-in-place as protection against a release of airborne hazardous material : report of a literature search.; TOPICAL

    International Nuclear Information System (INIS)

    ''Temporary shelter-in place'' is the combination of prompt shelter-in-place (SIP) to minimize initial exposure to airborne hazardous material, followed by timely action to terminate this protection to minimize exposure to hazardous vapor accumulations in the shelter once the air outside becomes less hazardous than the air inside the shelter. Temporary SIP, if properly executed, is considered to be an effective way to protect populations from hazardous chemical vapors, especially from high concentrations for short periods. This is supported by laboratory and field experiments. The need for timely termination of temporary SIP as protection from infiltrated vapors is an integral component of a temporary SIP strategy. It was from this premise that Argonne National Laboratory (ANL) was asked to develop methodologies for deciding when and how to terminate SIP. These methodologies, in turn, could be the basis for site-specific operational guidelines (e.g., decision matrix, decision-tree, or algorithm) for terminating SIP on each of the eight Army chemical stockpile storage sites, and in the off-post communities surrounding them. This project consists of two tasks. Task 1 was to collect and analyze existing literature that might be relevant to the termination of temporary SIP. This report is the product of Task 1. Task 2, which will begin on 2 February 2001, will use the results of the literature search as the baseline to investigate the concepts associated with temporary SIP, and to develop methodologies for termination of temporary SIP that can be incorporated in site-specific operational guidelines. It is understood that these methods will be consistent with Chemical Stockpile Emergency Preparedness Program (CSEPP) policy that ''the most important objective of the emergency preparedness and implementation process is the avoidance of fatalities to the maximum extent practicable, should an accidental release of chemical agent occur.'' It is also anticipated that these

  7. 3D scanning and 3D printing as innovative technologies for fabricating personalized topical drug delivery systems.

    Science.gov (United States)

    Goyanes, Alvaro; Det-Amornrat, Usanee; Wang, Jie; Basit, Abdul W; Gaisford, Simon

    2016-07-28

    Acne is a multifactorial inflammatory skin disease with high prevalence. In this work, the potential of 3D printing to produce flexible personalised-shape anti-acne drug (salicylic acid) loaded devices was demonstrated by two different 3D printing (3DP) technologies: Fused Deposition Modelling (FDM) and stereolithography (SLA). 3D scanning technology was used to obtain a 3D model of a nose adapted to the morphology of an individual. In FDM 3DP, commercially produced Flex EcoPLA™ (FPLA) and polycaprolactone (PCL) filaments were loaded with salicylic acid by hot melt extrusion (HME) (theoretical drug loading - 2% w/w) and used as feedstock material for 3D printing. Drug loading in the FPLA-salicylic acid and PCL-salicylic acid 3D printed patches was 0.4% w/w and 1.2% w/w respectively, indicating significant thermal degradation of drug during HME and 3D printing. Diffusion testing in Franz cells using a synthetic membrane revealed that the drug loaded printed samples released manufacture anti-acne devices with salicylic acid. The combination of 3D scanning and 3D printing has the potential to offer solutions to produce personalised drug loaded devices, adapted in shape and size to individual patients. PMID:27189134

  8. 3D scanning and 3D printing as innovative technologies for fabricating personalized topical drug delivery systems.

    Science.gov (United States)

    Goyanes, Alvaro; Det-Amornrat, Usanee; Wang, Jie; Basit, Abdul W; Gaisford, Simon

    2016-07-28

    Acne is a multifactorial inflammatory skin disease with high prevalence. In this work, the potential of 3D printing to produce flexible personalised-shape anti-acne drug (salicylic acid) loaded devices was demonstrated by two different 3D printing (3DP) technologies: Fused Deposition Modelling (FDM) and stereolithography (SLA). 3D scanning technology was used to obtain a 3D model of a nose adapted to the morphology of an individual. In FDM 3DP, commercially produced Flex EcoPLA™ (FPLA) and polycaprolactone (PCL) filaments were loaded with salicylic acid by hot melt extrusion (HME) (theoretical drug loading - 2% w/w) and used as feedstock material for 3D printing. Drug loading in the FPLA-salicylic acid and PCL-salicylic acid 3D printed patches was 0.4% w/w and 1.2% w/w respectively, indicating significant thermal degradation of drug during HME and 3D printing. Diffusion testing in Franz cells using a synthetic membrane revealed that the drug loaded printed samples released 3D printing technology to manufacture anti-acne devices with salicylic acid. The combination of 3D scanning and 3D printing has the potential to offer solutions to produce personalised drug loaded devices, adapted in shape and size to individual patients.

  9. Use of Immunostimulatory Sequence-Containing Oligonucleotides as Topical Therapy for Genital Herpes Simplex Virus Type 2 Infection

    Science.gov (United States)

    Pyles, Richard B.; Higgins, Debbie; Chalk, Claudia; Zalar, Anthony; Eiden, Joseph; Brown, Carrie; Van Nest, Gary; Stanberry, Lawrence R.

    2002-01-01

    Synthetic oligonucleotides containing CpG motifs in specific sequence contexts have been shown to induce potent immune responses. We have evaluated mucosal administration of two immunostimulatory sequence (ISS)-containing phosphorothioate-stabilized oligonucleotides for antiherpetic efficacy in animal models. The ISS oligonucleotides, suspended in phosphate-buffered saline, were tested in mouse and guinea pig vaginal models of herpes simplex virus type 2 (HSV-2) infection. For comparison, groups of untreated, non-ISS oligonucleotide-treated, and acyclovir-treated animals also were monitored. The results indicated that vaginal epithelial application of ISS (up to 6 h after viral inoculation) with mice lethally challenged with HSV-2 delayed disease onset and reduced the number of animals that developed signs of disease (P = 0.003). ISS application significantly increased survival rates over those of controls (P = 0.0014). The ISS also impacted an established infection in the guinea pig model of HSV-2 disease. A single administration of ISS (21 days after viral inoculation) significantly reduced the frequency and severity of HSV-2 lesions compared to results with non-ISS oligonucleotide-treated and untreated guinea pigs (P < 0.01). HSV-2 is shed from the vaginal cavity of the guinea pig in the absence of lesions, similar to the case with humans. As an additional indication of ISS efficacy, the magnitude of viral shedding also was significantly reduced in ISS-treated animals (P < 0.001). These effects appeared to be immunologically mediated, since ISS had no direct effect on HSV-2 replication in vitro using standard plaque assays. These data suggest that ISS may be useful in the treatment and control of genital herpes in humans. PMID:12388699

  10. Mental Mechanisms for Topics Identification

    Directory of Open Access Journals (Sweden)

    Louis Massey

    2014-01-01

    Full Text Available Topics identification (TI is the process that consists in determining the main themes present in natural language documents. The current TI modeling paradigm aims at acquiring semantic information from statistic properties of large text datasets. We investigate the mental mechanisms responsible for the identification of topics in a single document given existing knowledge. Our main hypothesis is that topics are the result of accumulated neural activation of loosely organized information stored in long-term memory (LTM. We experimentally tested our hypothesis with a computational model that simulates LTM activation. The model assumes activation decay as an unavoidable phenomenon originating from the bioelectric nature of neural systems. Since decay should negatively affect the quality of topics, the model predicts the presence of short-term memory (STM to keep the focus of attention on a few words, with the expected outcome of restoring quality to a baseline level. Our experiments measured topics quality of over 300 documents with various decay rates and STM capacity. Our results showed that accumulated activation of loosely organized information was an effective mental computational commodity to identify topics. It was furthermore confirmed that rapid decay is detrimental to topics quality but that limited capacity STM restores quality to a baseline level, even exceeding it slightly.

  11. Analysis of Cartoon Characters in Advertisement Plan%广告策划中运用的卡通形象分析

    Institute of Scientific and Technical Information of China (English)

    秦斯杨

    2011-01-01

    In the era of competitive business market, and the information society that lack of emotional interaction, the design of creating a cartoon image with affinity which is close to people's hearts is just emerging and will become the inevitable trend of development. On the basis of analyzing the status quo of cartoon image and the differences of cartoon characters from other images, the paper gave a success example of cartoon images in advertising planning, thinks about the design and development of using cartoon image in the future advertising art.%在市场竞争激烈的商业年代,在正处缺乏情感交流的信息社会,创造一个具有亲和力和贴近人们的内心的卡通形象设计领域正在刚刚兴起,并会成为这个时代必然的发展趋势.文章在分析卡通形象现状以及卡通形象运用和其他形象运用的差别的基础上,通过例举卡通形象在广告策划中的成功案例,深入思考了未来广告艺术中卡通形象的设计与发展.

  12. Human-competitive automatic topic indexing

    CERN Document Server

    Medelyan, Olena

    2009-01-01

    Topic indexing is the task of identifying the main topics covered by a document. These are useful for many purposes: as subject headings in libraries, as keywords in academic publications and as tags on the web. Knowing a document’s topics helps people judge its relevance quickly. However, assigning topics manually is labor intensive. This thesis shows how to generate them automatically in a way that competes with human performance. Three kinds of indexing are investigated: term assignment, a task commonly performed by librarians, who select topics from a controlled vocabulary; tagging, a popular activity of web users, who choose topics freely; and a new method of keyphrase extraction, where topics are equated to Wikipedia article names. A general two-stage algorithm is introduced that first selects candidate topics and then ranks them by significance based on their properties. These properties draw on statistical, semantic, domain-specific and encyclopedic knowledge. They are combined using a machine learn...

  13. 卡通表情诱发的视觉失匹配负波研究%Studies of Visual Mismatch Negativity Elicited by Cartoon Facial Expressions

    Institute of Scientific and Technical Information of China (English)

    季淑梅; 李围; 刘鹏; 边志杰

    2013-01-01

    采用修正的“跨通道延迟反应”实验范式,探讨卡通表情能否诱发视觉失匹配负波(VMMN)及表情信息自动加工机制.两种短纯音与三种卡通表情图片伪随机排列,分时呈现,受试者听到刺激后,迅速对刺激类型做出判断并作好按键准备,当出现反应命令信号后尽快按键,听觉刺激与反应命令信号之间插入0~2个卡通表情图片.结果发现,视觉偏差刺激(愉快、愤怒表情)事件相关电位(ERP)减去标准刺激(中性表情)ERP得到两种VMMN,愤怒表情诱发的VMMN较愉快表情诱发的VMMN更负,两者存在左半球偏侧趋势,表明卡通表情可以诱发出VMMN,表情信息能被自动加工.%A modified “cross-modal delayed response” paradigm was used to investigate whether the visual mismatch negativity can be elicited by cartoon facial expressions,and to define the mechanism underlying automatic processing of facial expressions.Subjects taking part in the tests were instructed to discriminate the type of the tones they heard as quickly and accurately as possible,and to act merely when they heard the response imperative signal.Neutral,happy and angry faces were presented during intervals between a tone and a response imperative signal.Visual mismatch negativity (VMMN) was obtained by subtracting the event-related potential (ERP) elicited by neutral faces from that elicited by happy faces or angry faces.The angry-related VMMN was more negative than happy-related VMMN,and both were more negative in the left than in the right cerebral hemisphere.The results indicated that VMMN can be elicited by the cartoon facial expressions,and the facial expressions can be processed automatically.

  14. Music Perception as a Topic of Cognitive Psychology = Bilişsel Psikolojinin Bir Konusu Olarak Müzik Algısı

    Directory of Open Access Journals (Sweden)

    Aslı ASLAN

    2007-06-01

    Full Text Available Music perception has a long and distinguished history as a topic of psychological research because music requires a mental activity in humans. As a complex human activity, music perception is naturally an area of interest especially to cognitive psychology. Cognitive studies suggest that listener’s experience of a particular musical sequence is driven and at the same time constrained by the sounds registered by auditory mechanisms but also processed by available mental resources. This assumption indicates that researchers must take into account certain inherent limitations and capabilities of the listener. The main purpose of this paper is to discuss possible cognitive processes underlying music perception. The steps taken towards this purpose will be describing the structure of music and discussing the way that this structure is perceived by human cognition.

  15. Topical report review status

    International Nuclear Information System (INIS)

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  16. Design of Block Copolymer Costabilized Nonionic Microemulsions and Their In Vitro and In Vivo Assessment as Carriers for Sustained Regional Delivery of Ibuprofen via Topical Administration.

    Science.gov (United States)

    Djekic, Ljiljana; Martinovic, Martina; Stepanović-Petrović, Radica; Tomić, Maja; Micov, Ana; Primorac, Marija

    2015-08-01

    Nonionic surfactants (caprylocaproyl macrogol-8 glycerides, octoxynol-12, polysorbate-20, and polyethylene glycol-40 hydrogenated castor oil) (47.03%, w/w), costabilizer (poloxamer 407) (12%-20%, w/w), oil (isopropyl myristate) (5.22%, w/w), water (q.s. ad 100%, w/w), and ibuprofen (5%, w/w) were used to develop oil-in-water microemulsions with Newtonian flow behavior, low viscosity (from 368 ± 38 to 916 ± 46 mPa s), and average droplet size from 14.79 ± 0.31 to 16.54 ± 0.75 nm. Ibuprofen in vitro release from the microemulsions was in accordance with zero-order kinetics (R0(2) > 0.99) for at least 12 h. The maximum drug release rate (3.55%h(-1) ) was from the microemulsion M3 comprising 16%, w/w of poloxamer 407. The release rate of ibuprofen from the reference hydrogel followed Higuchi kinetics (RH(2) > 0.99), and drug amount released after the 6th hour was negligible. In a rat model of inflammation, the microemulsion M3 was significantly more efficacious than the reference hydrogel in exerting antihyperalgesic effects in prophylactic topical treatment, whereas they were comparable in therapeutic treatment as well as in producing antiedematous effect in both protocols. No obvious skin irritation was observed in in vivo studies. The developed nonionic surfactants-based microemulsions containing the optimal concentration of poloxamer 407 could be promising carriers for sustained regional delivery of ibuprofen via topical administration. PMID:26045240

  17. Topical or oral administration with an extract of Polypodium leucotomos prevents acute sunburn and psoralen-induced phototoxic reactions as well as depletion of Langerhans cells in human skin

    International Nuclear Information System (INIS)

    Sunburn, immune suppression, photo-aging, and skin cancers result from uncontrolled overexposure of human skin to solar ultraviolet radiation (UVR). Preventive measures, including photo-protection, are helpful and can be achieved by topical sun-screening agents. Polypodium leucotomos (PL) has been used for the treatment of inflammatory diseases and has shown some in vitro and in vivo immunomodulating properties. Its beneficial photo-protective effects in the treatment of vitiligo and its antioxidant properties encouraged us to evaluate in vivo the potentially useful photo-protective property of natural extract of PL after topical application or oral ingestion. Twenty-one healthy volunteers [either untreated or treated with oral psoralens (8-MOP or 5-MOP)] were enrolled in this study and exposed to solar radiation for evaluation of the following clinical parameters: immediate pigment darkening (IPD), minimal erythema dose (MED), minimal melanogenic dose (MMD), and minimal phototoxic dose (MPD) before and after topical or oral administration of PL. Immunohistochemical assessment of CD1a-expressing epidermal cells were also performed. PL was found to be photo-protective after topical application as well as oral administration. PL increased UV dose required for IPD (P<0.01), MED (P<0.001) and MPD (P<0.001). After oral administration of PL, MED increased 2.,8±0.59 times and MPD increased 2.75±0.5 and 6.8±1.3 times depending upon the type of psoralen used. Immunohistochemical study revealed photo-protection of Langherhans cells by oral as well as topical PL. The observed photo-protective activities of oral or topical PL reveal a new avenue in examining the potentially useful field of systemic photo-protection and suggests that PL can be used as adjunct treatment and can make photochemotherapy and phototherapy possibly safe and effective when the control of cutaneous phototoxicity to PUVA or UVB is a limiting factor in such photo-therapies. (au)

  18. Topics in atomic physics

    CERN Document Server

    Burkhardt, Charles E

    2006-01-01

    The study of atomic physics propelled us into the quantum age in the early twentieth century and carried us into the twenty-first century with a wealth of new and, in some cases, unexplained phenomena. Topics in Atomic Physics provides a foundation for students to begin research in modern atomic physics. It can also serve as a reference because it contains material that is not easily located in other sources. A distinguishing feature is the thorough exposition of the quantum mechanical hydrogen atom using both the traditional formulation and an alternative treatment not usually found in textbooks. The alternative treatment exploits the preeminent nature of the pure Coulomb potential and places the Lenz vector operator on an equal footing with other operators corresponding to classically conserved quantities. A number of difficult to find proofs and derivations are included as is development of operator formalism that permits facile solution of the Stark effect in hydrogen. Discussion of the classical hydrogen...

  19. Syntacticized topics in Kurmuk

    DEFF Research Database (Denmark)

    Andersen, Torben

    2015-01-01

    . The grammatical relation of the topic is expressed by a voice-like inflection of the verb, here called orientation. While subject-orientation is morphologically unmarked, object-oriented and adjunct-oriented verbs are marked by a subject suffix or by a suffix indicating that the topic is not subject, and adjunct...

  20. Salicylic Acid Topical

    Science.gov (United States)

    ... skin blemishes in people who have acne. Topical salicylic acid is also used to treat skin conditions that involve scaling or overgrowth of skin ... water for 15 minutes.Do not apply topical salicylic acid to skin that is broken, red, swollen, irritated, or infected. ...

  1. An ionic liquid-in-water microemulsion as a potential carrier for topical delivery of poorly water soluble drug: Development, ex-vivo and in-vivo evaluation.

    Science.gov (United States)

    Goindi, Shishu; Kaur, Ramanpreet; Kaur, Randeep

    2015-11-30

    In this paper, we report an ionic liquid-in-water (IL/w) microemulsion (ME) formulation which is able to solubilize etodolac (ETO), a poorly water soluble drug for topical delivery using BMIMPF6 (1-butyl-3-methylimidazolium hexafluorophosphate) as IL, Tween 80 as surfactant and ethanol as co-surfactant. The prepared ME was characterized for physicochemical parameters, subjected to ex-vivo permeation studies as well as in-vivo pharmacodynamic evaluation. The ex-vivo drug permeation studies through rat skin was performed using Franz-diffusion cell and the IL/w based ME showed maximum mean cumulative percent permeation of 99.030±0.921% in comparison to oil-in-water (o/w) ME (61.548±1.875%) and oily solution (48.830±2.488%) of ETO. In-vivo anti-arthritic and anti-inflammatory activities of the prepared formulations were evaluated using different rodent models and the results revealed that ETO loaded IL/w based ME was found to be more effective in controlling inflammation than oily solution, o/w ME and marketed formulation of ETO. Histopathological studies also demonstrated that IL/w based ME caused no anatomical and pathological changes in the skin. PMID:26456294

  2. Topic Identification in Discourse

    CERN Document Server

    Chen, K

    1995-01-01

    This paper proposes a corpus-based language model for topic identification. We analyze the association of noun-noun and noun-verb pairs in LOB Corpus. The word association norms are based on three factors: 1) word importance, 2) pair co-occurrence, and 3) distance. They are trained on the paragraph and sentence levels for noun-noun and noun-verb pairs, respectively. Under the topic coherence postulation, the nouns that have the strongest connectivities with the other nouns and verbs in the discourse form the preferred topic set. The collocational semantics then is used to identify the topics from paragraphs and to discuss the topic shift phenomenon among paragraphs.

  3. Application of Cartoon in Middle School Geography Teaching%浅析初中地理教学中漫画的运用

    Institute of Scientific and Technical Information of China (English)

    史士利

    2011-01-01

    Geographic cartoons as part of geography classroom, which is both direct and intuitive. Not only can make the concept of abstract geographic visualization, visualization, to stimulate student interest, but also can stimulate students to think actively ex- plored. In the geography classroom can be used on a comic introduction, case studies and exercises. Read comics from the five geographical areas to interpret: the title, the resulting problems, causes, and the harm, and solution measures.%地理漫画作为地理课堂的一分子,既直接又直观。不仅可使抽象的地理概念形象化、直观化、激发学生的兴趣,而且还可以激发学生积极思考主动探索。在地理课堂上漫画可用作导言、案例和习题。解读地理漫画要从五个方面来解读:标题、产生的问题、产生的原因、产生的危害和解决的措施。

  4. Clinical application of oral form of ANGIPARSTM and in combination with topical form as a new treatment for diabetic foot ulcers: A randomized clinical trial

    OpenAIRE

    Bahrami A; Kamali K; Ali-Asgharzadeh A; Hosseini P; Heshmat R; HR Khorram Khorshid; Gharibdoust F; SH Madani; Larijani B

    2008-01-01

    ANGIPARSTM is a new herbal extract which has been produced in oral, topical, and intravenous forms. The present article contains preliminary results of the study which was planned to evaluate the efficacy and safety of orally applied ANGIPARSTM and to compare it with the combination of oral and topical forms and also with conventional therapy in patients with diabetic ulcers of the lower extremities."nTwenty one patients with diabetic foot ulcers were divided into 3 groups. The first gro...

  5. A Survey of Topic Modeling in Text Mining

    Directory of Open Access Journals (Sweden)

    Rubayyi Alghamdi

    2015-01-01

    Full Text Available Topic models provide a convenient way to analyze large of unclassified text. A topic contains a cluster of words that frequently occur together. A topic modeling can connect words with similar meanings and distinguish between uses of words with multiple meanings. This paper provides two categories that can be under the field of topic modeling. First one discusses the area of methods of topic modeling, which has four methods that can be considerable under this category. These methods are Latent semantic analysis (LSA, Probabilistic latent semantic analysis (PLSA, Latent Dirichlet allocation (LDA, and Correlated topic model (CTM. The second category is called topic evolution models, which model topics by considering an important factor time. In the second category, different models are discussed, such as topic over time (TOT, dynamic topic models (DTM, multiscale topic tomography, dynamic topic correlation detection, detecting topic evolution in scientific literature, etc.

  6. Parent's alcoholism severity and family topic avoidance about alcohol as predictors of perceived stigma among adult children of alcoholics: Implications for emotional and psychological resilience.

    Science.gov (United States)

    Haverfield, Marie C; Theiss, Jennifer A

    2016-01-01

    Alcoholism is a highly stigmatized condition, with both alcohol-dependent individuals and family members of the afflicted experiencing stigmatization. This study examined the severity of a parent's alcoholism and family topic avoidance about alcohol as two factors that are associated with family members' perceptions of stigma. Three dimensions of stigma were considered: discrimination stigma, disclosure stigma, and positive aspect stigma. In addition, this study assessed associations between perceived stigmatization and individuals' experiences of depressive symptoms, self-esteem, and resilience. Adult children of alcoholics (N = 622) were surveyed about family conditions, perceived stigma, and their emotional and psychological well-being. Regression analyses revealed that the severity of a parent's alcoholism predicted all three types of stigma for females, but not for males. In addition, family topic avoidance about alcohol predicted all types of stigma for males and discrimination stigma and positive aspect stigma for females. With few exceptions, the three types of stigma predicted depressive symptoms, self-esteem, and resilience for both male and female adult children of alcoholics. The results are discussed in terms of their implications for promoting a family environment that mitigates stigma and encourages emotional and psychological well-being. In 2012, approximately 3.3 million deaths worldwide were due to the harmful use of alcohol (World Health Organization [WHO], 2014). Individuals who abuse alcohol are susceptible to a variety of negative health outcomes (Rehm et al., 2009) and display inappropriate social behaviors (Klingemann, 2001; Schomerus et al., 2011a). General societal perceptions tend to characterize alcohol-dependent individuals as irresponsible and lacking in self-control (Schomerus et al., 2011b). Research in the United Kingdom found that 54% of the population believes alcohol-dependent individuals are personally to blame for their own

  7. Maps on the basis of the Arts & Humanities Citation Index: The journals Leonardo and Art Journal versus "Digital Humanities" as a topic

    CERN Document Server

    Leydesdorff, Loet

    2009-01-01

    The possibilities of using the Arts & Humanities Citation Index (A&HCI) for journal mapping have not been sufficiently recognized because of the absence of a Journal Citations Report (JCR) for this database. A quasi-JCR for the A&HCI (2008) was constructed from the data contained in the Web-of-Science and is used for the evaluation of two journals as examples: Leonardo and Art Journal. The maps on the basis of the aggregated journal-journal citations within this domain can be compared with maps including references to journals in the Science Citation Index and Social Science Citation Index. Art journals are cited by (social) science journals more than by other art journals, but these journals draw upon one another in terms of their own references. This cultural impact in terms of being cited is not found when documents with a topic such as "digital humanities" are analyzed. This community of practice functions more as an intellectual organizer than a journal.

  8. Dynamic construction and the media ideology in multimodal metaphors in political cartoons%政治漫画中多模态隐喻的动态构建与媒体的意识形态

    Institute of Scientific and Technical Information of China (English)

    常军芳

    2015-01-01

    The multimodal metaphor, refers to the source field and target domain respectively by different symbols mode of metaphor. Political cartoons are images and language combination of the two symbols of a visual modal discourse, belong to multimodal discourse; Through the combination of image and language construct meaning, create a complete social events, has a strong purpose. From cognitive perspective, this paper based on the multimodal metaphor theory, combined with the theory of visual image analysis under the framework of systemic functional grammar, tries to analyze three metaphor and metonymy in the cartoon, as well as the cultural connotation, and analyze the importance of comic creators of ideology, political position of the choice of the source domain metaphor and metonymy, then explain how political cartoons consolidate relying on the conceptual metaphors different elements such as the events, people, environment, and realize composition.%多模态隐喻是指源域和目标域分别由不同符号模式呈现的隐喻.政治漫画是图像和语言文字这两种符号相结合的一种视觉模态语篇,属于多模态话语;其通过图像和语言文字共同作用构建意义,创造出完整的交际事件,具有很强的目的性.本文从认知角度出发,以多模态隐喻理论为基础,结合系统功能语法框架下的视觉图像分析理论,尝试分析3幅漫画中的隐喻和转喻现象及文化内涵,并分析漫画创作者的意识形态、政治立场对隐喻和转喻的源域选择的重要性,进而说明政治漫画如何依托概念隐喻将事件、人物、环境等不同要素进行整合,实现构图意义.

  9. Identifying Topics in Microblogs Using Wikipedia.

    Science.gov (United States)

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

    2016-01-01

    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail. PMID:26991442

  10. Identifying Topics in Microblogs Using Wikipedia.

    Directory of Open Access Journals (Sweden)

    Ahmet Yıldırım

    Full Text Available Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA, propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision and other observations from the study are discussed in detail.

  11. Identifying Topics in Microblogs Using Wikipedia

    Science.gov (United States)

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan

    2016-01-01

    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail. PMID:26991442

  12. Topics in current aerosol research

    CERN Document Server

    Hidy, G M

    1971-01-01

    Topics in Current Aerosol Research deals with the fundamental aspects of aerosol science, with emphasis on experiment and theory describing highly dispersed aerosols (HDAs) as well as the dynamics of charged suspensions. Topics covered range from the basic properties of HDAs to their formation and methods of generation; sources of electric charges; interactions between fluid and aerosol particles; and one-dimensional motion of charged cloud of particles. This volume is comprised of 13 chapters and begins with an introduction to the basic properties of HDAs, followed by a discussion on the form

  13. Topics in millimeter wave technology

    CERN Document Server

    Button, Kenneth

    1988-01-01

    Topics in Millimeter Wave Technology, Volume 1 presents topics related to millimeter wave technology, including fin-lines and passive components realized in fin-lines, suspended striplines, suspended substrate microstrips, and modal power exchange in multimode fibers. A miniaturized monopulse assembly constructed in planar waveguide with multimode scalar horn feeds is also described. This volume is comprised of five chapters; the first of which deals with the analysis and synthesis techniques for fin-lines as well as the various passive components realized in fin-line. Tapers, discontinuities,

  14. Interdiction of images: the construction of the other in Mohammed’s cartoons A interdição das imagens: a construção do outro pelas charges de Maomé

    Directory of Open Access Journals (Sweden)

    Maria Luisa Hoffmann

    2009-08-01

    Full Text Available This paper analyses the building of Islam as an inverted image of western culture, as a result of the publication of cartoons representing prophet Mohammed in a Danish newspaper in September of 2005. The association of the prophet to terrorism in images is discussed in light of the contributions of semiotics of culture and authors such as Vilém Flusser and Norval Baitello Jr. Este artigo analisa a construção do islã como imagem invertida do ocidente através da publicação das Charges de Maomé em um jornal dinamarquês em setembro de 2005. A associação do profeta islâmico com o terrorismo em imagens é discutida à luz de pressupostos teóricos da semiótica da cultura e de autores como Vilém Flusser e Norval Baitello Júnior.

  15. Using an Animated Cartoon Hero in Video Instruction to Improve Bathroom-Related Skills of a Student with Autism Spectrum Disorder

    Science.gov (United States)

    Ohtake, Yoshihisa; Takahashi, Ayaka; Watanabe, Kentaro

    2015-01-01

    The present study investigated the effectiveness of video hero modeling (VHM) for building four bathroom-related behaviors of an elementary-aged student with autism spectrum disorder. In the VHM intervention, the participant watched a video immediately before going to the bathroom he typically used. In the video, an animated face of a cartoon hero…

  16. Topics in Nuclear Astrophysics

    International Nuclear Information System (INIS)

    Some topics in nuclear astrophysics are discussed, e.g.: highly evolved stellar cores, stellar evolution (through the temperature analysis of stellar surface), nucleosynthesis and finally the solar neutrino problem. (L.C.)

  17. Diclofenac Topical (osteoarthritis pain)

    Science.gov (United States)

    ... should know that you should not apply sunscreens, cosmetics, lotions, moisturizers, insect repellents, or other topical medications ... that is bloody or looks like coffee grounds slow, shallow, or irregular breathing hives itching difficulty breathing ...

  18. Advanced Topics in Aerodynamics

    DEFF Research Database (Denmark)

    Filippone, Antonino

    1999-01-01

    "Advanced Topics in Aerodynamics" is a comprehensive electronic guide to aerodynamics,computational fluid dynamics, aeronautics, aerospace propulsion systems, design and relatedtechnology. We report data, tables, graphics, sketches,examples, results, photos, technical andscientific literature, for...

  19. Supplemental topics on voids

    Energy Technology Data Exchange (ETDEWEB)

    Rood, H.J.

    1988-09-01

    Several topics concerning voids are presented, supplementing the report of Rood (1988). The discovery of the Coma supercluster and void and the recognition of the cosmological significance of superclusters and voids are reviewed. Galaxy redshift surveys and redshift surveys for the Abell clusters and very distant objects are discussed. Solar system and extragalactic dynamics are examined. Also, topics for future observational research on voids are recommended. 50 references.

  20. Topical treatment of melasma

    Directory of Open Access Journals (Sweden)

    Bandyopadhyay Debabrata

    2009-01-01

    Full Text Available Melasma is a common hypermelanotic disorder affecting the face that is associated with considerable psychological impacts. The management of melasma is challenging and requires a long-term treatment plan. In addition to avoidance of aggravating factors like oral pills and ultraviolet exposure, topical therapy has remained the mainstay of treatment. Multiple options for topical treatment are available, of which hydroquinone (HQ is the most commonly prescribed agent. Besides HQ, other topical agents for which varying degrees of evidence for clinical efficacy exist include azelaic acid, kojic acid, retinoids, topical steroids, glycolic acid, mequinol, and arbutin. Topical medications modify various stages of melanogenesis, the most common mode of action being inhibition of the enzyme, tyrosinase. Combination therapy is the preferred mode of treatment for the synergism and reduction of untoward effects. The most popular combination consists of HQ, a topical steroid, and retinoic acid. Prolonged HQ usage may lead to untoward effects like depigmentation and exogenous ochronosis. The search for safer alternatives has given rise to the development of many newer agents, several of them from natural sources. Well-designed controlled clinical trials are needed to clarify their role in the routine management of melasma.

  1. Recent Advances In Topical Therapy In Dermatology

    Directory of Open Access Journals (Sweden)

    Mohan Thappa Devinder

    2003-01-01

    Full Text Available With changing times various newer topical agents are introduced in the field of dermatology. Tacrolimus and pimecrolimus are immunisuppressants, which are effective topically and are tried in the management of atopic dermatitis as well as other disorders including allergic contact dermatitis, atrophic lichen planus, pyoderma gangrenosum. Imiquimod, an immune response modifier, is presently in use for genital warts but has potentials as anti- tumour agent and in various other dermatological conditions when used topically. Tazarotene is a newer addition to the list of topical reginoids, which is effective in psoriasis and has better effect in combination with calcipotriene, phototherapy and topical costicosteroids. Tazarotene and adapelene are also effective in inflammatory acne. Calcipotriol, a vitamin D analogue has been introduced as a topical agent in the treatment of psoriasis. Steroid components are also developed recently which will be devoid of the side effects but having adequate anti-inflammatory effect. Topical photodynamic therapy has also a wide range of use in dermatology. Newer topical agents including cidofovir, capsaicin, topical sensitizers, topical antifungal agents for onychomycosis are also of use in clinical practice. Other promising developments include skin substitutes and growth factors for wound care.

  2. Implicit stage topics

    Directory of Open Access Journals (Sweden)

    Karen Lahousse

    2008-04-01

    Full Text Available Il a souvent été proposé que les éléments spatio-temporels en position initiale de phrase spécifient le cadre de l’événement dénoté par la proposition et ont une interprétation thématique ou topicale. Alors que les topiques spatio-temporels explicites ont souvent été étudiés, Erteschik-Schir (1997, 1999 propose l’idée que les topiques spatio-temporels, ou topiques scéniques (stage topics peuvent aussi être implicites.Dans cet article, nous offrons des arguments en faveur de la notion de topique scénique implicite. Nous montrons qu’un certain nombre de cas d’inversion nominale en français, une configuration syntaxique qui est favorisée par la présence d’un topique scénique explicite, s’expliquent par la présence d’un topique scénique implicite. Le fait que les topiques scéniques implicites interagissent avec la structure syntaxique de la même façon que les topiques scéniques explicites constitue un argument empirique en faveur de leur existence.It has often been proposed that sentence-initial spatio-temporal elements specify the frame in which the whole proposition takes place and are topical (i.e. thematic. Whereas considerable attention has been paid to explicit spatio-temporal topics, Erteschik-Shir (1997, 1999 argues that spatio-temporal topics, or stage topics, can also be implicit.In this article we provide evidence in favour of the notion of implicit stage topic. We show that a certain number of nominal inversion cases in French, a syntactic configuration which is triggered by the presence of an explicit stage topic, are explained by the presence of an implicit stage topic. The fact that implicit stage topics interact with syntactic structure the same way explicit stage topics do constitutes a strong empirical argument in favour of their existence.

  3. Superconcentration and related topics

    CERN Document Server

    Chatterjee, Sourav

    2014-01-01

    A certain curious feature of random objects, introduced by the author as “super concentration,” and two related topics, “chaos” and “multiple valleys,” are highlighted in this book. Although super concentration has established itself as a recognized feature in a number of areas of probability theory in the last twenty years (under a variety of names), the author was the first to discover and explore its connections with chaos and multiple valleys. He achieves a substantial degree of simplification and clarity in the presentation of these findings by using the spectral approach. Understanding the fluctuations of random objects is one of the major goals of probability theory and a whole subfield of probability and analysis, called concentration of measure, is devoted to understanding these fluctuations. This subfield offers a range of tools for computing upper bounds on the orders of fluctuations of very complicated random variables. Usually, concentration of measure is useful when more direct prob...

  4. Topics in statistical mechanics

    International Nuclear Information System (INIS)

    This thesis deals with four independent topics in statistical mechanics: (1) the dimer problem is solved exactly for a hexagonal lattice with general boundary using a known generating function from the theory of partitions. It is shown that the leading term in the entropy depends on the shape of the boundary; (2) continuum models of percolation and self-avoiding walks are introduced with the property that their series expansions are sums over linear graphs with intrinsic combinatorial weights and explicit dimension dependence; (3) a constrained SOS model is used to describe the edge of a simple cubic crystal. Low and high temperature results are derived as well as the detailed behavior near the crystal facet; (4) the microscopic model of the lambda-transition involving atomic permutation cycles is reexamined. In particular, a new derivation of the two-component field theory model of the critical behavior is presented. Results for a lattice model originally proposed by Kikuchi are extended with a high temperature series expansion and Monte Carlo simulation. 30 references

  5. Parent's alcoholism severity and family topic avoidance about alcohol as predictors of perceived stigma among adult children of alcoholics: Implications for emotional and psychological resilience.

    Science.gov (United States)

    Haverfield, Marie C; Theiss, Jennifer A

    2016-01-01

    Alcoholism is a highly stigmatized condition, with both alcohol-dependent individuals and family members of the afflicted experiencing stigmatization. This study examined the severity of a parent's alcoholism and family topic avoidance about alcohol as two factors that are associated with family members' perceptions of stigma. Three dimensions of stigma were considered: discrimination stigma, disclosure stigma, and positive aspect stigma. In addition, this study assessed associations between perceived stigmatization and individuals' experiences of depressive symptoms, self-esteem, and resilience. Adult children of alcoholics (N = 622) were surveyed about family conditions, perceived stigma, and their emotional and psychological well-being. Regression analyses revealed that the severity of a parent's alcoholism predicted all three types of stigma for females, but not for males. In addition, family topic avoidance about alcohol predicted all types of stigma for males and discrimination stigma and positive aspect stigma for females. With few exceptions, the three types of stigma predicted depressive symptoms, self-esteem, and resilience for both male and female adult children of alcoholics. The results are discussed in terms of their implications for promoting a family environment that mitigates stigma and encourages emotional and psychological well-being. In 2012, approximately 3.3 million deaths worldwide were due to the harmful use of alcohol (World Health Organization [WHO], 2014). Individuals who abuse alcohol are susceptible to a variety of negative health outcomes (Rehm et al., 2009) and display inappropriate social behaviors (Klingemann, 2001; Schomerus et al., 2011a). General societal perceptions tend to characterize alcohol-dependent individuals as irresponsible and lacking in self-control (Schomerus et al., 2011b). Research in the United Kingdom found that 54% of the population believes alcohol-dependent individuals are personally to blame for their own

  6. The Health Curriculum: 500 Topics.

    Science.gov (United States)

    Byrd, Oliver E.

    2001-01-01

    This 1958 paper divides 500 health topics into 20 categories: health as a social accomplishment/social problem; nutrition; physical fitness; mental health and disease; heredity/eugenics; infection/immunity; chronic and degenerative disease; substance abuse; skin care; vision, hearing, and speech; dental health; safety; physical environment; health…

  7. Selected topics in nuclear structure

    International Nuclear Information System (INIS)

    19. winter school in Zakopane was devoted to selected topics in nuclear structure such as: production of spin resonances, heavy ions reactions and their applications to the investigation of high spin states, octupole deformations, excited states and production of new elements etc. The experimental data are ofen compared with theoretical predictions. Report contains 28 papers. (M.F.W.)

  8. Topics in optics and music

    Science.gov (United States)

    Sparks, Andrew W.

    2012-10-01

    While the use of optics in the playback of music has been a tremendously successful technology and laser light shows are a common occurrence, other intersections of optics and music tend to be less well known. Topics such as optics-based instruments, performance tools and effects, instrument characterization and manufacturing, recording, playback, and signal processing are explored.

  9. Endoscopic Resection and Topical 5-Fluorouracil as an Alternative Treatment to Craniofacial Resection for the Management of Primary Intestinal-Type Sinonasal Adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Simon Mackie

    2010-01-01

    Conclusion. Trans-nasal endoscopic resection and topical 5-Fluorouracil could potentially offer an acceptable alternative treatment to the standard of cranio-facial resection. This should be investigated in trials with a longer followup period than this paper in order to directly compare the two treatment modalities.

  10. Researching Distressing Topics

    Directory of Open Access Journals (Sweden)

    Sharon Jackson

    2013-05-01

    Full Text Available Qualitative researchers who explore sensitive topics may expose themselves to emotional distress. Consequently, researchers are often faced with the challenge of maintaining emotional equilibrium during the research process. However, discussion on the management of difficult emotions has occupied a peripheral place within accounts of research practice. With rare exceptions, the focus of published accounts is concentrated on the analysis of the emotional phenomena that emerge during the collection of primary research data. Hence, there is a comparative absence of a dialogue around the emotional dimensions of working with secondary data sources. This article highlights some of the complex ways in which emotions enter the research process during secondary analysis, and the ways in which we engaged with and managed emotional states such as anger, sadness, and horror. The concepts of emotional labor and emotional reflexivity are used to consider the ways in which we “worked with” and “worked on” emotion. In doing so, we draw on our collective experiences of working on two collaborative projects with ChildLine Scotland in which a secondary analysis was conducted on children’s narratives of distress, worry, abuse, and neglect.

  11. Topical Products for the Aging Face.

    Science.gov (United States)

    McCook, John P

    2016-07-01

    This article focuses on nonprescription home-use topical treatment technologies for the aging face and is intended to serve as a guide for the core cosmeceutical technologies currently used and to help educate and assist the selection of topical antiaging products by the professional staff and their patients. Antiaging topical treatments for patient home use should be nonirritating, compatible with the patient skin type, effective, and complementary to surgical and minimally invasive office procedures, and aesthetically elegant. New topical antiaging technologies, formulated as monotherapy or as combinations with well-known cosmeceuticals, should present adequate clinical studies to support their selection for use. PMID:27363774

  12. Skin oxygenation after topical application of liposome-entrapped benzyl nicotinate as measured by EPR oximetry in vivo: influence of composition and size.

    Science.gov (United States)

    Kristl, Julijana; Abramović, Zrinka; Sentjurc, Marjeta

    2003-01-01

    New and improved drug delivery systems are the important subject of much scientific research. The development of formulations that increase skin oxygenation and of methods for measuring oxygen levels in skin are important for dealing with healing processes affected by the level of oxygen. We have used EPR oximetry in vivo to compare the influence of liposomal formulations of different size and composition with that of hydrogel with respect to the action of the entrapped benzyl nicotinate (BN). Following the topical application of BN onto the skin of mice, pO2 increase was measured by low-frequency EPR as a function of time. The effect of BN was evaluated by 3 different parameters: lag-time, time needed for maximum pO2 increase, and overall effectiveness expressed by the area under the response-time curve. An increase in skin oxygenation was observed after BN application. The results show that the effect of BN incorporated in liposomes is achieved more rapidly than the effect from hydrophilic gel. The composition of the liposomes significantly affects the time at which BN starts to act and, to a lesser extent, the maximum increase of pO2 in skin and the effectiveness of BN action. However, the size of the liposomes influences both the effectiveness of BN action and the time at which BN starts to act. After repeated application of liposomes, the pO2 baseline increased and the response of the skin tissue was faster. Our results demonstrate that EPR oximetry is a useful method for evaluating oxygen changes after drug application and for following the time course of their action. PMID:12713274

  13. Britannia : Grandeur et infortune d’une allégorie nationale dans l’univers du cartoon britannique 1842-1999 Britannia: Greatness and Misfortune of a National Symbol in the World of British Cartoons 1842-1999

    Directory of Open Access Journals (Sweden)

    Gilbert Millat

    2009-11-01

    Full Text Available Britannia, sometimes accompanied by the emblematic British Lion, has long been personifying justice, liberty, and the British Empire on coins and stamps as well as in graphic satire. Originally of Roman origin, she became the visual representation of Britain after being revived in the sixteenth century. This article is based on the analysis of over four hundred cartoons featuring this symbol. It argues that between 1860 and the 1950s, Britannia striking a solemn pose, that of the Græco-Roman goddess created by Tenniel, exalted Victorian greatness and the early twentieth century great power twice victorious in the World Wars. On the other hand, since the inter-war years, Low and his followers had been challenging this supposedly immutable image. They turned her into a definitely helpless and obsolete symbol whose identity was sometimes usurped by such anti-heroes as Colonel Blimp. Finally, from the 1960s, in a context of continuous British decline and growing permissiveness, cartoonists increasingly followed the example of the old masters of 18th century caricature and early Punch cartoonists, even though aggressiveness and vulgarity have remained much less explicit.

  14. El discurso infantil sobre valores y emociones a partir tres muertes clave en los relatos audiovisuales / Children's discourse about values and emotions through three examples of deaths in the cartoon movies

    Directory of Open Access Journals (Sweden)

    Leticia PORTO PEDROSA

    2013-12-01

    Full Text Available Este artículo pretende acercarse a la comprensión de la audiencia infantil ante determinados contenidos audiovisuales que transmiten valores y emociones vinculadas al sufrimiento y al dolor. Se trata de un trabajo que realiza un recorrido por las clásicas películas de dibujos animados y los modernos largometrajes de animación que han formado parte del entretenimiento de distintas generaciones. En este repaso, nos centramos en tres momentos clave que consideramos que han marcado un punto de inflexión en este tipo de cine: la muerte de la madre en la película Bambi (1942; el asesinato del padre de Simba, en El Rey León (1994 y, el tercero, la despedida de Ellie, en Up (2009. Para profundizar en la comprensión de los niños sobre esta clase de contenidos emocionales presentes en estas historias, se lleva a cabo una investigación cualitativa realizada a través de grupos de discusión con menores. This article discusses about the understanding of children as viewers of audiovisual content that broadcast values and emotions related to suffering and pain. This research reviews of the classic cartoons movies and modern animation films that have been part of the entertainment of different generations. In this paper, we focus on three key moments that we believe could be a turning point for this kind of cartoon movies: the death of the mother of Bambi (1942, the murder of the Simba's father in The Lion King (1994 and Ellie's death in Up (2009. In orden to know the understanding of children on these emotional content present in these stories, it develop a qualitative research through focus groups with children.

  15. 网络游戏玩家对卡通面孔的偏好研究%The Research of the Online Gamers' Preference for Car-toon Faces

    Institute of Scientific and Technical Information of China (English)

    吴洁清; 贺司琪; 史媛媛

    2013-01-01

    本研究采用问卷调查和实验研究相结合的方法探究了角色扮演类游戏玩家对角色扮演类游戏中卡通面孔偏好的类型,结果发现:(1)面孔类型效应上,文静/斯文,可爱,美丽/英俊这三种卡通面孔特征对玩家和非玩家均具有更好的吸引力。(2)性别效应上,男性比女性更偏爱冷酷、妩媚、残暴的卡通面孔特征。(3)玩家类型效应上,角色扮演类游戏玩家比非玩家更喜欢冷酷卡通面孔特征。此研究结论有助于探讨网络游戏成瘾的心理机制。%The research adopted the method of questionnaire sur-vey and experimental study to investigate the preference of the role-playing online gamer for the cartoon face. Results showed that:firstly, these three facial types as quiet or gentle ones, cute ones and beautiful or handsome ones were more attractive to these gamers. Secondly, males tended to prefer the cool, charm-ing and violent characteristics more than females. Thirdly, the role-playing gamers preferred the cool cartoon face types more than the non-role-playing gamers. These findings will help to explore the psychological mechanisms of online game addiction.

  16. Tracking topic birth and death in LDA.

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Andrew T.; Robinson, David Gerald

    2011-09-01

    Most topic modeling algorithms that address the evolution of documents over time use the same number of topics at all times. This obscures the common occurrence in the data where new subjects arise and old ones diminish or disappear entirely. We propose an algorithm to model the birth and death of topics within an LDA-like framework. The user selects an initial number of topics, after which new topics are created and retired without further supervision. Our approach also accommodates many of the acceleration and parallelization schemes developed in recent years for standard LDA. In recent years, topic modeling algorithms such as latent semantic analysis (LSA)[17], latent Dirichlet allocation (LDA)[10] and their descendants have offered a powerful way to explore and interrogate corpora far too large for any human to grasp without assistance. Using such algorithms we are able to search for similar documents, model and track the volume of topics over time, search for correlated topics or model them with a hierarchy. Most of these algorithms are intended for use with static corpora where the number of documents and the size of the vocabulary are known in advance. Moreover, almost all current topic modeling algorithms fix the number of topics as one of the input parameters and keep it fixed across the entire corpus. While this is appropriate for static corpora, it becomes a serious handicap when analyzing time-varying data sets where topics come and go as a matter of course. This is doubly true for online algorithms that may not have the option of revising earlier results in light of new data. To be sure, these algorithms will account for changing data one way or another, but without the ability to adapt to structural changes such as entirely new topics they may do so in counterintuitive ways.

  17. Topics in Nonlinear Dynamics

    DEFF Research Database (Denmark)

    Mosekilde, Erik

    Through a significant number of detailed and realistic examples this book illustrates how the insights gained over the past couple of decades in the fields of nonlinear dynamics and chaos theory can be applied in practice. Aomng the topics considered are microbiological reaction systems, ecological...

  18. Topic: Mastery Learning.

    Science.gov (United States)

    Killoran, James, Ed.

    1983-01-01

    This journal issue addresses the topic of mastery learning at both the elementary and secondary school levels. The first article, "The Theory and Practice of Mastery Learning" (Guskey), gives a definition of and information about the development, operation, and application of mastery learning, based on the theories of Benjamin Bloom. In addition,…

  19. Topical Research: Africa.

    Science.gov (United States)

    Lynn, Karen

    This lesson plan can be used in social studies, language arts, or library research. The instructional objective is for students to select a topic of study relating to Africa, write a thesis statement, collect information from media sources, and develop a conclusion. The teacher may assign the lesson for written or oral evaluation. The teacher…

  20. Contrastive topics decomposed

    Directory of Open Access Journals (Sweden)

    Michael Wagner

    2012-12-01

    Full Text Available The analysis of contrastive topics introduced in Büring 1997b and further developed in Büring 2003 relies on distinguishing two types of constituents that introduce alternatives: the sentence focus, which is marked by a FOC feature, and the contrastive topic, which is marked by a CT feature. A non-compositional rule of interpretation that refers to these features is used to derive a topic semantic value, a nested set of sets of propositions. This paper presents evidence for a correlation between the restrictive syntax of nested focus operators and the syntax of contrastive topics, a correlation which is unexpected under this analysis. A compositional analysis is proposed that only makes use of the flatter focus semantic values introduced by focus operators. The analysis aims at integrating insights from the original analysis while at the same time capturing the observed syntactic restrictions. http://dx.doi.org/10.3765/sp.5.8 BibTeX info

  1. Characters and Topical Diversity

    DEFF Research Database (Denmark)

    Eriksson, Rune

    2014-01-01

    The purpose of this article is to contribute to our understanding of the difference between the bestseller and the non-bestseller in nonfiction. It is noticed that many bestsellers in nonfiction belongs to the sub-genre of creative nonfiction, but also that the topics in this kind of literature i...

  2. Updates of Topical and Local Anesthesia Agents.

    Science.gov (United States)

    Boyce, Ricardo A; Kirpalani, Tarun; Mohan, Naveen

    2016-04-01

    As described in this article, there are many advances in topical and local anesthesia. Topical and local anesthetics have played a great role in dentistry in alleviating the fears of patients, eliminating pain, and providing pain control. Many invasive procedures would not be performed without the use and advances of topical/local anesthetics. The modern-day dentist has the responsibility of knowing the variety of products on the market and should have at least references to access before, during, and after treatment. This practice ensures proper care with topical and local anesthetics for the masses of patients entering dental offices worldwide. PMID:27040295

  3. The treatment of rosacea with topical ivermectin.

    Science.gov (United States)

    Ali, S T; Alinia, H; Feldman, S R

    2015-04-01

    The treatment of rosacea is challenging because several pathophysiologic processes may be involved, including neurovascular dysregulation and alterations in innate immune status. Demodex mites may play a role in the latter mechanism. Topical ivermectin is a new therapeutic modality which demonstrates antiparasitic and anti-inflammatory properties. This article reviews published evidence related to the efficacy and safety of topical ivermectin. PubMed was utilized to search for key words "topical ivermectin", "ivermectin cream" and "rosacea". Three clinical trials were found that studied topical ivermectin as a treatment option for rosacea. Ivermectin was effective, safe and well tolerated. PMID:26020066

  4. Topics and topic prominence in two sign languages

    NARCIS (Netherlands)

    V. Kimmelman

    2015-01-01

    In this paper we describe topic marking in Russian Sign Language (RSL) and Sign Language of the Netherlands (NGT) and discuss whether these languages should be considered topic prominent. The formal markers of topics in RSL are sentence-initial position, a prosodic break following the topic, and non

  5. The pharmacology of topical analgesics.

    Science.gov (United States)

    Barkin, Robert L

    2013-07-01

    systemic circulation, topically applied analgesics are associated with application-site reactions in patients, such as dryness, erythema, burning, and discoloration. Furthermore, some adverse events that have been observed in patients may be suggestive of some degree of systemic exposure. This article reviews the mechanisms of action, pharmacokinetics, and tolerability of topical treatments for the management of patient pain.

  6. Analyses of Research Topics in the Field of Informetrics Based on the Method of Topic Modeling

    OpenAIRE

    Sung-Chien Lin

    2014-01-01

    In this study, we used the approach of topic modeling to uncover the possible structure of research topics in the field of Informetrics, to explore the distribution of the topics over years, and to compare the core journals. In order to infer the structure of the topics in the field, the data of the papers published in the Journal of Informetricsand Scientometrics during 2007 to 2013 are retrieved from the database of the Web of Science as input of the approach of topic modeling. The results ...

  7. 将数字增白美容技法用于DIY卡通肖像%Introduce a Digital Whitening Technique to DIY a Cartoon Portrait

    Institute of Scientific and Technical Information of China (English)

    彭革刚; 李新宇; 宋鹰; 向黎生; 沈清; 封模春; 石猛

    2012-01-01

    爱美之心人皆有之,对于黄种人而言,往往以皮肤白嫩为美。面向这一普遍愿望,该项目通过自行设计的颜色迁移和图像融合算法,以数码照片为素材,改造成不同款式的、具有增白嫩肤效果的作品,以满足青年人特别是年轻女孩的愿望。该项目的另一内容是模拟炭精画效果。将炭精画作为美白润肤的极致,希望通过模拟炭精画的技法将肖像改造成一幅别致的绘画艺术品。%Everyone has the heart of beauty, for yellow person, they often like to acquire a white and delicate face. Oriented on such a general desire, our project design and realize an image color transferring and image concretizing algorithm. Based on such software, a digital photo can be re-created to a better cartoon portrait and have whitening tenderizing effect. This is a good result to meet young people's need in particular the young girl's. Other content of this project is to simulate the graphite paintings in effect. We consider the graphite paintings as an ultimate whitening effect, by introduce a graphite painting simulating technique, a young person may transform a portrait into unique graphite paintings work him-self.

  8. Hot topic [editorial

    International Nuclear Information System (INIS)

    simulations 'would be seriously in error'. One may ask if this magazine should give space to Lindzen or those involved in geoengineering to air their views. Given the uncertainties still present within climate models and the potential costs of dealing with global warming, it would be wrong for Physics World to ignore those outside the mainstream. After all, as Richard Feynman once wrote: 'There is no harm in doubt and scepticism, for it is through these that new discoveries are made'. Physicists should never take anything at face value, not least a topic as important as climate change. (U.K.)

  9. Topical retinoids for acne.

    Science.gov (United States)

    Yeh, Lindsey; Bonati, Lauren Meshkov; Silverberg, Nanette B

    2016-06-01

    Topical retinoids are currently approved by the US Food and Drug Administration for the treatment of acne vulgaris in nonpregnant, nonlactating patients 12 years of age and older. Their efficacy, safety, and tolerability are well documented for inflammatory and noninflammatory acne with studies repeatedly demonstrating a decrease in the number of lesions, significant improvement in acne severity, improvement in the cosmetic appearance of acne, and the prevention of acne lesions through microcomedone formation. There is some variability between prescription retinoid products regarding efficacy, safety, and tolerability; with erythema, peeling, and dryness being common, potential side effects. Due to their efficacious and safe profile, topical retinoids remain the first-line treatment for acne vulgaris. PMID:27416308

  10. Psoriasis: improving adherence to topical therapy.

    NARCIS (Netherlands)

    Feldman, S.R.; Horn, E.J.; Balkrishnan, R.; Basra, M.K.; Finlay, A.Y.; McCoy, D.; Menter, A.; Kerkhof, P.C.M. van de

    2008-01-01

    Topical therapy has an important role in psoriasis treatment. It is efficacious and has a favorable safety profile as demonstrated in clinical trials. However, poor treatment outcomes from topical therapy regimens likely result from poor adherence and ineffective use of the medication. The Internati

  11. Four (Somewhat Nonstandard) Research Topics

    OpenAIRE

    Paun, Gheorghe; Research Group on Natural Computing (Universidad de Sevilla) (Coordinador)

    2014-01-01

    Four research directions are suggested, dealing with the following four main ideas: computing along the axon (up to now, this topic was only preliminarily investi- gated), using pre-computed resources in order to solve computationally hard problems, considering in P systems both objects \\of matter" and \\of anti-matter" (which annihilate each other when meet), and considering the distance (naturally de ned in a membrane structure of a given type) as a support of information.

  12. Influence of food companies' brand mascots and entertainment companies' cartoon media characters on children's diet and health: a systematic review and research needs

    OpenAIRE

    Kraak, VI; Story, M

    2014-01-01

    Reducing the extent and persuasive power of marketing unhealthy foods to children worldwide are important obesity prevention goals. Research is limited to understand how brand mascots and cartoon media characters influence children's diet. We conducted a systematic review of five electronic databases (2000–2014) to identify experimental studies that measured how food companies' mascots and entertainment companies' media characters influence up to 12 diet-related cognitive, behavioural and hea...

  13. Correlated Topic Model for Web Services Ranking

    Directory of Open Access Journals (Sweden)

    Mustapha AZNAG

    2013-07-01

    Full Text Available With the increasing number of published Web services providing similar functionalities, it’s very tedious for a service consumer to make decision to select the appropriate one according to her/his needs. In this paper, we explore several probabilistic topic models: Probabilistic Latent Semantic Analysis (PLSA, Latent Dirichlet Allocation (LDA and Correlated Topic Model (CTM to extract latent factors from web service descriptions. In our approach, topic models are used as efficient dimension reduction techniques, which are able to capture semantic relationships between word-topic and topic-service interpreted in terms of probability distributions. To address the limitation of keywords-based queries, we represent web service description as a vector space and we introduce a new approach for discovering and ranking web services using latent factors. In our experiment, we evaluated our Service Discovery and Ranking approach by calculating the precision (P@n and normalized discounted cumulative gain (NDCGn.

  14. The Construal of Multimodal Meanings in a Political Cartoon%多模态政治漫画语篇的意义构建

    Institute of Scientific and Technical Information of China (English)

    吴玉花

    2012-01-01

    Multimodal discourse analysis provides a new angle and an effective way to study the discourses made up of many modes.Based on the theoretical framework of the visual communication grammar,which is developed by Kressvan Leeuwen from Halliday's systemic functional linguistics,this paper studies how the multimodal representational,interactive and compositional meanings are construed in a political cartoon.The aim of this study is to explore the possibilities of analyzing multimodal cartoon discourse from a different perspective.It could provide a new theoretical viewpoint for the meaning construction,innovation and comprehension in political cartoons.%多模态语篇分析方法使得从新的视角有效解读多种符号组成的语篇成为可能,运用Kress&van Leeuwen的视觉图像分析语法框架探讨一则政治漫画的多模态再现、互动、构图意义的构建,旨在证明多模态语篇分析方法的解释力。分析表明:在系统功能语言学理论上发展起来的多模态语篇分析框架能够为政治漫画的语义构建、创新和理解提供一个新的理论平台。

  15. Topics in commutative ring theory

    CERN Document Server

    Watkins, John J

    2009-01-01

    Topics in Commutative Ring Theory is a textbook for advanced undergraduate students as well as graduate students and mathematicians seeking an accessible introduction to this fascinating area of abstract algebra. Commutative ring theory arose more than a century ago to address questions in geometry and number theory. A commutative ring is a set-such as the integers, complex numbers, or polynomials with real coefficients--with two operations, addition and multiplication. Starting from this simple definition, John Watkins guides readers from basic concepts to Noetherian rings-one of

  16. "Draw My Topics": Find Desired Topics fast from large scale of Corpus

    OpenAIRE

    Dou, Jason; Sun, Ni; Zou, Xiaojun

    2016-01-01

    We develop the "Draw My Topics" toolkit, which provides a fast way to incorporate social scientists' interest into standard topic modelling. Instead of using raw corpus with primitive processing as input, an algorithm based on Vector Space Model and Conditional Entropy are used to connect social scientists' willingness and unsupervised topic models' output. Space for users' adjustment on specific corpus of their interest is also accommodated. We demonstrate the toolkit's use on the Diachronic...

  17. Topical Acne Treatments and Pregnancy

    Science.gov (United States)

    Topical Acne Treatments and Pregnancy In every pregnancy, a woman starts out with a 3-5% chance of having ... This sheet talks about whether exposure to topical acne treatments may increase the risk for birth defects ...

  18. Recent Advances In Topical Therapy In Dermatology

    OpenAIRE

    Mohan Thappa Devinder

    2003-01-01

    With changing times various newer topical agents are introduced in the field of dermatology. Tacrolimus and pimecrolimus are immunisuppressants, which are effective topically and are tried in the management of atopic dermatitis as well as other disorders including allergic contact dermatitis, atrophic lichen planus, pyoderma gangrenosum. Imiquimod, an immune response modifier, is presently in use for genital warts but has potentials as anti- tumour agent and in various other dermatological co...

  19. 中国特色文化产业发展路径探析——基于“喜羊羊”成功个案的启示%Exploration on Development Route of Cultural Industry with Chinese Character---A Case Study of the Cartoon "Pleasant Goat and Grey Wolf"

    Institute of Scientific and Technical Information of China (English)

    赵欣

    2012-01-01

    作为迄今为止国内最成功的原创动漫品牌,"喜羊羊"的出现正是中国文化产业成长进程的缩影之一。在当前国际间文化竞争日益激烈的现实背景下,加快发展中国特色文化产业显得尤为重要而紧迫,"喜羊羊"的成功经验无疑能带来诸多有益的启示。%The cartoon "Pleasant Goatand Grey Wolf" , as a most successful cartoon made in China, can be regarded as the sign of Chinese cultural industry progress. With more fierce competition between countries in the world, the advancement of Chinese cultural industries is very important, which will obtain more shares in the international cultural market. The success of "Pleasant Goat and Grey Wolf" provides enlightenment for Chinese cultural industries.

  20. Simulation Model of Crowd Agonistic Behavior for Virtual Characters in Cartoon Games%动漫游戏中虚拟角色的一种群体对抗仿真模型

    Institute of Scientific and Technical Information of China (English)

    刘箴; 柴艳杰

    2012-01-01

    Computer is playing an important role in the research of social science, and modeling the behavior of human crowd is an interesting topic. A simulation method for human agonistic behavior within a limited space in cartoon games was explored. First, a 3D virtual scene and virtual characters were built, and a virtual character was equipped with physiology parameters, psychology parameters and social parameters. Second, an emotion decision model for fear and anger was proposed, and a formula of emotion influence was proposed. Finally, a 3D demo system of agonistic behavior was realized, and some preliminary laws were discovered based on changing the parameters of two antagonism crowds.%计算机在社会科学的研究中正扮演着重要的角色,建立人类群体的行为模型是一个令人感兴趣的话题。采用动漫游戏,探索了一种面向有限空间中人类对抗行为的仿真方法。首先,建立了一个三维虚拟场景和虚拟角色,虚拟角色包含生理参数、心理参数和社会参数。其次,提出了一种情绪决策模型,主要考虑了恐惧和愤怒两种情绪,给出了情绪影响公式。最后,实现了一个三维对抗行为演示原型,通过改变对抗群体的参数,初步发现了一些对抗规律。

  1. Potential theory—selected topics

    CERN Document Server

    Aikawwa, Hiroaki

    1996-01-01

    The first part of these lecture notes is an introduction to potential theory to prepare the reader for later parts, which can be used as the basis for a series of advanced lectures/seminars on potential theory/harmonic analysis. Topics covered in the book include minimal thinness, quasiadditivity of capacity, applications of singular integrals to potential theory, L(p)-capacity theory, fine limits of the Nagel-Stein boundary limit theorem and integrability of superharmonic functions. The notes are written for an audience familiar with the theory of integration, distributions and basic functional analysis.

  2. Control of pain with topical plant medicines

    Institute of Scientific and Technical Information of China (English)

    James; David; Adams; Jr.; Xiaogang; Wang

    2015-01-01

    Pain is normally treated with oral nonsteroidal anti-inflammatory agents and opioids. These drugs are dangerous and are responsible for many hospitalizations and deaths. It is much safer to use topical preparations made from plants to treat pain, even severe pain. Topical preparations must contain compounds that penetrate the skin, inhibit pain receptors such as transient receptor potential cation channels and cyclooxygenase-2, to relieve pain. Inhibition of pain in the skin disrupts the pain cycle and avoids exposure of internal organs to large amounts of toxic compounds. Use of topical pain relievers has the potential to save many lives, decrease medical costs and improve therapy.

  3. Digital Social Network Mining for Topic Discovery

    Science.gov (United States)

    Moradianzadeh, Pooya; Mohi, Maryam; Sadighi Moshkenani, Mohsen

    Networked computers are expanding more and more around the world, and digital social networks becoming of great importance for many people's work and leisure. This paper mainly focused on discovering the topic of exchanging information in digital social network. In brief, our method is to use a hierarchical dictionary of related topics and words that mapped to a graph. Then, with comparing the extracted keywords from the context of social network with graph nodes, probability of relation between context and desired topics will be computed. This model can be used in many applications such as advertising, viral marketing and high-risk group detection.

  4. OS SUPER-HERÓIS EM AÇÃO. PODEM OS DESENHOS ANIMADOS SUGERIREM UMA ORIENTAÇÃO ESTÉTICA LÚDICO-AGRESSIVA? SUPERHEROES IN ACTION: THE AESTHETIC ORIENTATION OF CARTOONS

    Directory of Open Access Journals (Sweden)

    Raquel Firmino Magalhães Barbosa

    2013-05-01

    Full Text Available Partindo do ponto que o homem é considerado um ser simbólico e influenciado diretamente pelos aspectos sociais e culturais, o seu imaginário é totalmente estimulado por tudo e todos que estão a sua volta, principalmente na contemporaneidade, quando o que está em voga é a infância, a TV e suas brincadeiras. Este estudo objetivou conhecer a dinâmica brincante entre os heróis de alguns desenhos animados (Power Rangers, Ben 10, Homem Aranha e Homem de Ferro e a orientação estética desta teia de relações, a partir das metáforas e construções teóricas de Ariès, Brougère, Jones, Huizinga, Morin, Sutton-Smith, dentre outros. Partindo do pressuposto que a criança utiliza a sua imaginação para brincar com o que está ao seu redor e que os objetos que compõem este meio também podem influenciá-la, foram formuladas as seguintes indagações: como o processo de identificação com o desenho animado age para suscitar a imaginação das crianças? Como a agressividade permeia suas brincadeiras? Foram realizadas entrevistas com sete crianças de cinco anos de idade da Educação Infantil de uma Escola Municipal de Cuiabá/MT. O texto apresentou a importância de ter uma percepção sensível sobre a relação que a criança faz com seus heróis midiáticos: a escolha da brincadeira, a preferência do personagem e os comportamentos lúdico-agressivos presentes neste momento. Isso possibilitou uma experiência estética, de mostrar a linguagem lúdica da criança ao interpretar à sua maneira o conteúdo dos desenhos animados.Starting from the point of view that the man is considered to be a symbolic being and directly influenced by social and cultural aspects, his imagination is fully stimulated by everything and everyone that is around him, especially when what is in vogue in contemporaneity is childhood, TV and playing. This study aimed to understand the playful dynamics between cartoon heroes (Power Rangers, Ben 10, Spider-man and

  5. Analyses of Research Topics in the Field of Informetrics Based on the Method of Topic Modeling

    Directory of Open Access Journals (Sweden)

    Sung-Chien Lin

    2014-07-01

    Full Text Available In this study, we used the approach of topic modeling to uncover the possible structure of research topics in the field of Informetrics, to explore the distribution of the topics over years, and to compare the core journals. In order to infer the structure of the topics in the field, the data of the papers published in the Journal of Informetricsand Scientometrics during 2007 to 2013 are retrieved from the database of the Web of Science as input of the approach of topic modeling. The results of this study show that when the number of topics was set to 10, the topic model has the smallest perplexity. Although data scopes and analysis methodsare different to previous studies, the generating topics of this study are consistent with those results produced by analyses of experts. Empirical case studies and measurements of bibliometric indicators were concerned important in every year during the whole analytic period, and the field was increasing stability. Both the two core journals broadly paid more attention to all of the topics in the field of Informetrics. The Journal of Informetricsput particular emphasis on construction and applications ofbibliometric indicators and Scientometrics focused on the evaluation and the factors of productivity of countries, institutions, domains, and journals.

  6. Hierarchical topic modeling with nested hierarchical Dirichlet process

    Institute of Scientific and Technical Information of China (English)

    Yi-qun DING; Shan-ping LI; Zhen ZHANG; Bin SHEN

    2009-01-01

    This paper deals with the statistical modeling of latent topic hierarchies in text corpora. The height of the topic tree is assumed as fixed, while the number of topics on each level as unknown a priori and to be inferred from data. Taking a nonparametric Bayesian approach to this problem, we propose a new probabilistic generative model based on the nested hierarchical Dirichlet process (nHDP) and present a Markov chain Monte Carlo sampling algorithm for the inference of the topic tree structure as welt as the word distribution of each topic and topic distribution of each document. Our theoretical analysis and experiment results show that this model can produce a more compact hierarchical topic structure and captures more free-grained topic relationships compared to the hierarchical latent Dirichlet allocation model.

  7. Advanced verification topics

    CERN Document Server

    Bhattacharya, Bishnupriya; Hall, Gary; Heaton, Nick; Kashai, Yaron; Khan Neyaz; Kirshenbaum, Zeev; Shneydor, Efrat

    2011-01-01

    The Accellera Universal Verification Methodology (UVM) standard is architected to scale, but verification is growing and in more than just the digital design dimension. It is growing in the SoC dimension to include low-power and mixed-signal and the system integration dimension to include multi-language support and acceleration. These items and others all contribute to the quality of the SOC so the Metric-Driven Verification (MDV) methodology is needed to unify it all into a coherent verification plan. This book is for verification engineers and managers familiar with the UVM and the benefits it brings to digital verification but who also need to tackle specialized tasks. It is also written for the SoC project manager that is tasked with building an efficient worldwide team. While the task continues to become more complex, Advanced Verification Topics describes methodologies outside of the Accellera UVM standard, but that build on it, to provide a way for SoC teams to stay productive and profitable.

  8. 75 FR 26647 - Ophthalmic and Topical Dosage Form New Animal Drugs; Ivermectin Topical Solution

    Science.gov (United States)

    2010-05-12

    ... parasites that were approved for the pioneer product with 3 years of marketing exclusivity (69 FR 501... HUMAN SERVICES Food and Drug Administration 21 CFR Part 524 Ophthalmic and Topical Dosage Form New... part 524 is amended as follows: PART 524--OPHTHALMIC AND TOPICAL DOSAGE FORM NEW ANIMAL DRUGS 0 1....

  9. Detection of Embryonic Research Topics by Analysing Semantic Topic Networks

    OpenAIRE

    Salatino, Angelo Antonio; Motta, Enrico

    2016-01-01

    Being aware of new research topics is an important asset for anybody involved in the research environment, including researchers, academic publishers and institutional funding bodies. In recent years, the amount of scholarly data available on the web has increased steadily, allowing the development of several approaches for detecting emerging research topics and assessing their trends. However, current methods focus on the detection of topics which are already associated with a label or a sub...

  10. A Survey On Interactivity in Topic Models

    Directory of Open Access Journals (Sweden)

    Patrik Ehrencrona Kjellin

    2016-04-01

    Full Text Available Trying to make sense and gain deeper insight from large sets of data is becoming a task very central to computer science in general. Topic models, capable of uncovering the semantic themes pervading through large collections of documents, have seen a surge in popularity in recent years. However, topic models are high level statistical tools; their output is given in terms of probability distributions, suited neither for simple interpretation nor deep analysis. Interpreting the fitted topic models in an intuitive manner requires visual and interactive tools. Additionally, some measure of human interaction is typically required for refining the output offered by such models. In the research, this area remains relatively unexplored – only recently has this aspect been receiving more attention. In this paper, the literature is surveyed as it pertains to interactivity and visualisation within the context of topic models, with the goal of finding current research trends in this area.

  11. 1/f 2 Characteristics and isotropy in the fourier power spectra of visual art, cartoons, comics, mangas, and different categories of photographs.

    Directory of Open Access Journals (Sweden)

    Michael Koch

    Full Text Available Art images and natural scenes have in common that their radially averaged (1D Fourier spectral power falls according to a power-law with increasing spatial frequency (1/f(2 characteristics, which implies that the power spectra have scale-invariant properties. In the present study, we show that other categories of man-made images, cartoons and graphic novels (comics and mangas, have similar properties. Further on, we extend our investigations to 2D power spectra. In order to determine whether the Fourier power spectra of man-made images differed from those of other categories of images (photographs of natural scenes, objects, faces and plants and scientific illustrations, we analyzed their 2D power spectra by principal component analysis. Results indicated that the first fifteen principal components allowed a partial separation of the different image categories. The differences between the image categories were studied in more detail by analyzing whether the mean power and the slope of the power gradients from low to high spatial frequencies varied across orientations in the power spectra. Mean power was generally higher in cardinal orientations both in real-world photographs and artworks, with no systematic difference between the two types of images. However, the slope of the power gradients showed a lower degree of mean variability across spectral orientations (i.e., more isotropy in art images, cartoons and graphic novels than in photographs of comparable subject matters. Taken together, these results indicate that art images, cartoons and graphic novels possess relatively uniform 1/f(2 characteristics across all orientations. In conclusion, the man-made stimuli studied, which were presumably produced to evoke pleasant and/or enjoyable visual perception in human observers, form a subset of all images and share statistical properties in their Fourier power spectra. Whether these properties are necessary or sufficient to induce aesthetic

  12. Topic Modeling of Hierarchical Corpora /

    OpenAIRE

    Kim, Do-kyum

    2014-01-01

    The sizes of modern digital libraries have grown beyond our capacity to comprehend manually. Thus we need new tools to help us in organizing and browsing large corpora of text that do not require manually examining each document. To this end, machine learning researchers have developed topic models, statistical learning algorithms for automatic comprehension of large collections of text. Topic models provide both global and local views of a corpus; they discover topics that run through the co...

  13. Synergetics introduction and advanced topics

    CERN Document Server

    Haken, Hermann

    2004-01-01

    This book is an often-requested reprint of two classic texts by H. Haken: "Synergetics. An Introduction" and "Advanced Synergetics". Synergetics, an interdisciplinary research program initiated by H. Haken in 1969, deals with the systematic and methodological approach to the rapidly growing field of complexity. Going well beyond qualitative analogies between complex systems in fields as diverse as physics, chemistry, biology, sociology and economics, Synergetics uses tools from theoretical physics and mathematics to construct an unifying framework within which quantitative descriptions of complex, self-organizing systems can be made. This may well explain the timelessness of H. Haken's original texts on this topic, which are now recognized as landmarks in the field of complex systems. They provide both the beginning graduate student and the seasoned researcher with solid knowledge of the basic concepts and mathematical tools. Moreover, they admirably convey the spirit of the pioneering work by the founder of ...

  14. Industrial Transformation: Research Gaps and Possible Research Topics for IIASA.

    OpenAIRE

    Mulder, P

    1997-01-01

    Industrial transformation has been identified as a priority research topic within the International Human Dimensions Programme on Global Environmental Change (IHDP). This paper looks at the research gaps in the area of Industrial Transformation identified within the framework of IHDP. Furthermore, the paper explores possible research topics for IIASA and discusses possible research questions for the topics of ``Technology'' and ``Consumption''.

  15. Generative Topic Modeling in Image Data Mining and Bioinformatics Studies

    Science.gov (United States)

    Chen, Xin

    2012-01-01

    Probabilistic topic models have been developed for applications in various domains such as text mining, information retrieval and computer vision and bioinformatics domain. In this thesis, we focus on developing novel probabilistic topic models for image mining and bioinformatics studies. Specifically, a probabilistic topic-connection (PTC) model…

  16. The Impact of Topic Congruence on Second Language Reading Comprehension

    Directory of Open Access Journals (Sweden)

    Marzieh Sadeghpour

    2013-09-01

    Full Text Available The present study scrutinized the impact of congruent topics on the quality of L2 reading comprehension. 56 Iranian advanced-level students read 2 texts on a controversial topic, one on the advantages of child gender selection, and the other on disadvantages. Quality analysis of immediate and delayed recall tasks, defined as the amount of high and low-level information recalled correctly, was performed by analysis of variance. Results revealed that topic congruence affected immediate recall of both high and low-level information, and also delayed recall of low-level information. Findings showed that the effect of congruent topics on reading recall was detrimental; participants recalled less information from the passage with congruent topic than a passage with incongruent topic. Outcomes of the study suggest that controversial topics should be selected more cautiously, because they may not truly reflect L2 readers’ reading comprehension. Keywords: congruent topic, L2 reading, readers’ attitude, immediate recall, delayed recall

  17. The topical treatment of psoriasis.

    NARCIS (Netherlands)

    Kerkhof, P.C.M. van de; Vissers, W.H.P.M.

    2003-01-01

    According to the patients, improvement of efficacy, long-term safety and improvement of compliance are needed. The topical treatment has been innovated during the last decade. Most important are the introduction of two new classes of treatments: topical vitamin D(3) analogues and the retinoid tazaro

  18. Topics of Evolutionary Computation 2001

    DEFF Research Database (Denmark)

    Ursem, Rasmus Kjær

    This booklet contains the student reports from the course: Topics of Evolutionary Computation, Fall 2001, given by Thiemo Krink, Rene Thomsen and Rasmus K. Ursem......This booklet contains the student reports from the course: Topics of Evolutionary Computation, Fall 2001, given by Thiemo Krink, Rene Thomsen and Rasmus K. Ursem...

  19. Topics in Banach space theory

    CERN Document Server

    Albiac, Fernando

    2016-01-01

    This text provides the reader with the necessary technical tools and background to reach the frontiers of research without the introduction of too many extraneous concepts. Detailed and accessible proofs are included, as are a variety of exercises and problems. The two new chapters in this second edition are devoted to two topics of much current interest amongst functional analysts: Greedy approximation with respect to bases in Banach spaces and nonlinear geometry of Banach spaces. This new material is intended to present these two directions of research for their intrinsic importance within Banach space theory, and to motivate graduate students interested in learning more about them. This textbook assumes only a basic knowledge of functional analysis, giving the reader a self-contained overview of the ideas and techniques in the development of modern Banach space theory. Special emphasis is placed on the study of the classical Lebesgue spaces Lp (and their sequence space analogues) and spaces of continuous f...

  20. THE BIBLICAL EPISODE ABOUT THE THREE TEMPTETIONS OF JESUS AS A TOPIC OF THE DIALOGUE BETWEEN F. M. DOSTOEVSKY AND V. A. ALEKSEEV

    Directory of Open Access Journals (Sweden)

    Babkina T. A.

    2008-11-01

    Full Text Available The article focuses on Dostoevsky's correspondence with the soloist of the Mariinsky Theater orchestra Vasily Alekseevich Alekseev, which appeared as a feedback after the release of "A Writer's Diary".

  1. Nanoparticles - A paradigm for topical drug delivery

    Directory of Open Access Journals (Sweden)

    Yogesh S Chaudhari

    2012-01-01

    Full Text Available Topical drug delivery is still a challenge due to the difficulties in controlling the active pharmaceutical ingredient (API fate within the skin. Due to the safety of the component material and controlled release abilities, nanoparticles offer an excellent opportunity for the rational delivery of drugs to the desired target site and hence these carrier systems are effectively used for topical delivery of variety of active principles for both pharmaceutical as well as cosmetic purposes. Recently, solid lipid nanoparticles (SLNs have shown a great potential as carriers for topical administration of active substances, principally owing to the possible targeting effect and controlled release in different skin strata. Also, nanostructured lipid carriers (NLCs are a new type of topical delivery system offering improved performance in terms of drug loading and long-term stability with the ability to form highly concentrated dispersions. Another invention in the field of topical drug delivery is the use of micellar nanoparticles (MNPs that offer a potentially fast and inexpensive pharmaceutical development model by using drugs already proven safe and effective to create new proprietary formulations. These novel drug delivery systems have gained much interest as they combine both the technology of lipid sciences and nanosciences, and hence may be better alternative carriers.

  2. 动画片对培养3~6岁幼儿道德品质的影响%Cartoon cultivating moral character of children 3 to 6 years old

    Institute of Scientific and Technical Information of China (English)

    苏青清

    2013-01-01

    The cartoon is a good partner for the growth of young children. Cartoon cute cartoon characters, funny role play and the kids love the story, so that every child has become a big fan of the cartoon. Childhood is an important period of an ideological and moral quality, 3 to 6-year-old child is at this critical age, young children's moral character is extremely important. Today, young children's favorite cartoon and watch cartoons time than ever before in-depth, a lot of cartoon characters become a kids mouth relish the object, the content of the cartoon has become the young children interact the focus, and 3 to 6-year-old child has a good imitation, therefore, the animated cartoon character has become a children imitated by the object. The cartoon has long been the most suitable for children to accept a kind of culture, education and forms of entertainment, and subtly influence the children first perception of the world, the feeling of beauty and ugliness, good and evil judge. Thus, the content of the cartoon, the central idea, and figures demeanor so cultured young children good moral character can not be underestimated.%  动画片是当今幼儿成长的好伙伴,动画片中可爱的卡通人物形象、滑稽的角色表演,孩子们喜欢的故事情节,都让每个孩子成为了动画片的忠实粉丝。儿童期是一个人思想道德品质形成的重要时期,3~6岁的幼儿正处在这个关键年龄段,从小培养孩子的道德品质是极为重要。现如今,幼儿对动画片的喜爱程度和看动画片的时间都比以前更加深入了,很多动画片里的人物成为了孩子们口中津津乐道的对象,动画片的内容已成为了幼儿相互交流的重点,而3~6岁孩子具有好模仿的特点,因此,动画片的卡通人物就成为了幼儿竞相模仿的对象。动画片早已是最适合孩子接受的一种文化、教育和娱乐形式,并潜移默化地影响着幼儿对世界的最初认知

  3. 不同淀粉对速冻卡通鸡块的品质影响研究%Study on effect of different starch on quality of quick-frozen cartoon chicken

    Institute of Scientific and Technical Information of China (English)

    王杨; 刘欣; 张萍

    2015-01-01

    以速冻卡通鸡块为研究对象,通过对比相同添加量的玉米淀粉、豌豆淀粉、马铃薯淀粉和木薯淀粉在对鸡块品质的影响发现:添加四种淀粉的产品在色泽、滋气味、手感和口感方面差异性不显著;在改善鸡块的弹性方面,木薯淀粉和马铃薯淀粉显著优于豌豆淀粉与玉米淀粉,其中木薯淀粉效果最好。%Quick-frozen cartoon chicken was taken as an object of study. The effects of different addition of the corn starch, pea starch, potato starch and cassava starch on the quality of chicken nuggets were compared. The results showed that there was no significant difference in color, smell, feel and taste of the products added with the four kinds of starches respectively. In the aspect of improving the elasticity of the chicken nuggets, cassava starch and potato starch were obviously better than the pea starch and corn starch. Among them the effect of cassava starch was best.

  4. On influence of the animated cartoon and application in children's language development and learning%浅析幼儿语言发展与学习中动画片的影响及具体运用

    Institute of Scientific and Technical Information of China (English)

    柯恒波

    2014-01-01

    在幼儿的家庭教育中,充分发挥动画片对于幼儿语言水平提升的推动作用,是十分重要及有效的。作为教师,和幼儿一起选择为合理的动画片进行观看,在规划详细的计划体系前提下,采取“细节讲述法”确保孩子听取正确的音节读法,采取“关键词提问法”确保孩子词汇量的进一步扩充,采取“多元观看法”确保孩子语言表述水平的全面提升。%In the family education of children, give full play to the role of animation for children language level role, is very important and effective. As a teacher, and children together to choose reasonable cartoon to watch, in the planning anddetailed planning premise, take the"detail"to ensure thatchildren listen to the correct pronunciation of syllable, take"keywords questioning method"to ensure the further expansion of the child's vocabulary, adopt a"multi view"to ensure full of ascending children language level.

  5. Influence of food companies' brand mascots and entertainment companies' cartoon media characters on children's diet and health: a systematic review and research needs.

    Science.gov (United States)

    Kraak, V I; Story, M

    2015-02-01

    Reducing the extent and persuasive power of marketing unhealthy foods to children worldwide are important obesity prevention goals. Research is limited to understand how brand mascots and cartoon media characters influence children's diet. We conducted a systematic review of five electronic databases (2000-2014) to identify experimental studies that measured how food companies' mascots and entertainment companies' media characters influence up to 12 diet-related cognitive, behavioural and health outcomes for children under 12 years. Eleven studies met the inclusion criteria. Studies used 21 unique popular media characters, but no brand mascots. Results suggest that cartoon media character branding can positively increase children's fruit or vegetable intake compared with no character branding. However, familiar media character branding is a more powerful influence on children's food preferences, choices and intake, especially for energy-dense and nutrient-poor foods (e.g. cookies, candy or chocolate) compared with fruits or vegetables. Future research should use a theoretically grounded conceptual model and larger and more diverse samples across settings to produce stronger findings for mediating and moderating factors. Future research can be used to inform the deliberations of policymakers, practitioners and advocates regarding how media character marketing should be used to support healthy food environments for children.

  6. fMRI activation of the fusiform gyrus and amygdala to cartoon characters but not to faces in a boy with autism.

    Science.gov (United States)

    Grelotti, David J; Klin, Ami J; Gauthier, Isabel; Skudlarski, Pawel; Cohen, Donald J; Gore, John C; Volkmar, Fred R; Schultz, Robert T

    2005-01-01

    Abnormal hypoactivation in the amygdala and fusiform gyrus, brain areas that participate in face processing and social cognition, has consistently been demonstrated in persons with autism. We investigated activity in these areas in a boy with autism, DD, who had a special interest in "Digimon" cartoon characters. DD individuates Digimon faster than familiar faces and objects, but he individuates familiar faces no faster than objects. In contrast, a typically developing boy with an interest in "Pokemon" cartoon characters is equally fast at individuating faces and Pokemon and faster at individuating faces and Pokemon than objects and Digimon. In addition, using functional magnetic resonance imaging (fMRI), we show that DD activates his amygdala and fusiform gyrus for perceptual discriminations involving Digimon but not for those involving familiar or unfamiliar faces. This pattern of activation is not seen in the typically developing control with an interest in Pokemon or in a second comparison case who has autism but no interest in Digimon. These results have important implications for our understanding of autism, cortical face specialization, and the possible role of the amygdala in the development of perceptual expertise. PMID:15707614

  7. Influence of food companies' brand mascots and entertainment companies' cartoon media characters on children's diet and health: a systematic review and research needs.

    Science.gov (United States)

    Kraak, V I; Story, M

    2015-02-01

    Reducing the extent and persuasive power of marketing unhealthy foods to children worldwide are important obesity prevention goals. Research is limited to understand how brand mascots and cartoon media characters influence children's diet. We conducted a systematic review of five electronic databases (2000-2014) to identify experimental studies that measured how food companies' mascots and entertainment companies' media characters influence up to 12 diet-related cognitive, behavioural and health outcomes for children under 12 years. Eleven studies met the inclusion criteria. Studies used 21 unique popular media characters, but no brand mascots. Results suggest that cartoon media character branding can positively increase children's fruit or vegetable intake compared with no character branding. However, familiar media character branding is a more powerful influence on children's food preferences, choices and intake, especially for energy-dense and nutrient-poor foods (e.g. cookies, candy or chocolate) compared with fruits or vegetables. Future research should use a theoretically grounded conceptual model and larger and more diverse samples across settings to produce stronger findings for mediating and moderating factors. Future research can be used to inform the deliberations of policymakers, practitioners and advocates regarding how media character marketing should be used to support healthy food environments for children. PMID:25516352

  8. Mimesis and Psychological Conflicts in Robert Coover's Cartoon%罗伯特·库弗《卡通》中的模拟和心理矛盾

    Institute of Scientific and Technical Information of China (English)

    周洁

    2012-01-01

    Robert Coover is one of the representatives of American postmodern novelists.Cartoon fully displays the main features of postmodern novels: meta-fiction,metaphors in mimesis,coexistence of reality and fantasy,etc..By analyzing the application of mimesis and psychological conflicts in Cartoon,this paper tries to reveal their implications,and at the same time,reveals that the lost of morality in society brings heavy burdens to people's heart.%罗伯特·库弗是美国后现代小说的代表作家,其代表作《卡通》充分体现了后现代小说的主要特征:元小说、模拟与隐喻、现实与虚幻的并存等等。本文通过分析模拟手法在《卡通》中的应用,揭示它们背后的隐含寓意,并对小说主人公进行心理剖析,论述了道德沦丧的社会给人们心理上带来的沉重负担。

  9. The Influence of Cartoon on Children's Pro-social Behav-ior%动画片对幼儿亲社会性行为的影响

    Institute of Scientific and Technical Information of China (English)

    徐晓坤; 于敏

    2014-01-01

    The society makes impacts on people through various channels directly or indirectly.With the vigorous development of cartoon,it becomes a popular TV form for children,at the same time,it brings the influence of many aspects on people' living.Human socialization is a very complicated process and also a process of lifetime.Especially in the early childhood,it is the best period of socialization.So the development of cartoon becomes important factors which make influence on the social-ization of human.%社会对人的影响是通过各种间接或直接的渠道进行的,随着动画片的蓬勃发展,它成了幼儿喜闻乐见的电视形式,给人们的生活带来了诸多方面的影响。人的社会化是一个极为复杂的过程,也是一个持续终生的过程,而幼儿期又是接受社会化的最佳时期,所以动画片的发展成为影响人社会化的重要因素。

  10. KEY TOPICS IN SPORTS MEDICINE

    Directory of Open Access Journals (Sweden)

    Amir Ali Narvani

    2006-12-01

    Full Text Available Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1 Sports injuries, rehabilitation and injury prevention, 2 Exercise physiology, fitness testing and training, 3 Drugs in sport, 4 Exercise and health promotion, 5 Sport and exercise for special and clinical populations, 6 The psychology of performance and injury. PURPOSE The Key Topics format provides extensive, concise information in an accessible, easy-to-follow manner. AUDIENCE The book is targeted the students and specialists in sports medicine and rehabilitation, athletic training, physiotherapy and orthopaedic surgery. The editors are authorities in their respective fields and this handbook depends on their extensive experience and knowledge accumulated over the years. FEATURES The book contains the information for clinical guidance, rapid access to concise details and facts. It is composed of 99 topics which present the information in an order that is considered logical and progressive as in most texts. Chapter headings are: 1. Functional Anatomy, 2. Training Principles / Development of Strength and Power, 3. Biomechanical Principles, 4. Biomechanical Analysis, 5. Physiology of Training, 6. Monitoring of Training Progress, 7. Nutrition, 8. Hot and Cold Climates, 9. Altitude, 10. Sport and Travelling, 11. Principles of Sport Injury Diagnosis, 12. Principles of Sport and Soft Tissue Management, 13. Principles of Physical Therapy and Rehabilitation, 14. Principles of Sport Injury Prevention, 15. Sports Psychology, 16. Team Sports, 17. Psychological Aspects of Injury in Sport, 18. Injury Repair Process, 19. Basic Biomechanics of Tissue Injury, 20. Plain Film Radiography in Sport, 21. Nuclear Medicine, 22. Diagnostic Ultrasound, 23. MRI Scan, 24. Other Imaging, 5. Head Injury, 26. Eye

  11. Do Students Who Get Low Grades Only in Research Methods Need the Same Help as Students Who Get Low Grades in All Topics in Psychology?

    Science.gov (United States)

    Barry, John A.

    2012-01-01

    Some psychology students achieve high grades in all classes except for research methods (RM). Previous research has usually treated low levels of achievement in RM as a unitary phenomenon, without reference to the grades the student is achieving in other subjects. The present internet survey explored preferences for learning RM in 140 psychology…

  12. Integrating Case Topics in Medical School Curriculum to Enhance Multiple Skill Learning: Using Fetal Alcohol Spectrum Disorders as an Exemplary Case

    Science.gov (United States)

    Paley, Blair; O'Connor, Mary J.; Baillie, Susan J.; Guiton, Gretchen; Stuber, Margaret L.

    2009-01-01

    Objectives: This article describes the use of fetal alcohol spectrum disorders (FASDs) as a theme to connect the learning of basic neurosciences with clinical applications across the age span within a systems-based, integrated curricular structure that emphasizes problem-based learning. Methods: In collaboration with the Centers for Disease…

  13. FORMULATION AND DEVELOPMENT OF TOPICAL NIOSOMAL GEL OF BCS CLASS - III ANTI-VIRAL DRUG FOR BETTER EFFICACY AS HERPES TREATMENT

    Directory of Open Access Journals (Sweden)

    Modi Kushal A.

    2012-03-01

    Full Text Available The objective of present research work was to formulate niosomal gel of ACV and to evaluate it for enhancements of skin permeation and skin retention characteristics. ACV niosomes were prepared by classical thin layer hydration method. The niosomal vesicles were separated by centrifugation method and further evaluated for percentage drug entrapment (PDE and vesicle mean geometric diameter. The separated niosomal vesicles were incorporated into the Carbopol® 971 gel base. The niosomal gel was further evaluated for skin retention characteristics, in vitro diffusion study and stability studies at accelerated and non-accelerated conditions. The batch F12 was considered as optimized batch as it showed minimum geometric mean diameter of vesicles (1.23 ± 0.19 μm and maximum PDE (58.71 ± 0.89 %. The in vitro diffusion study using human cadaver skin (HCS showed 1.57 times higher flux as compared to conventional ACV gel. The skin retention study reveals that the percentage drug retained was 4.92 times higher as compared to conventional ACV gel. The stability studies at 2-8 °C showed PDE 94.23% after 12 weeks whereas at accelerated condition it was found to be 90.11%.

  14. A Problematic Family Reunion of a Chinese-American in China: Issues of Face Abstract: As one of the heated topics in the intercultural communication studies, face issues have aroused world-wide attention in the academic field. This paper analyses thr...%ract: As one of the heated topics in the intercultural communication studies, face issues have aroused world-wide attention in the academic field. This paper analyses three critical incidents based on two face theories proposed by Brown and Levinson ...

    Institute of Scientific and Technical Information of China (English)

    曹凤琴

    2012-01-01

    As one of the heated topics in the intercultural communication studies, face issues have aroused world-wide attention in the academic field. This paper analyses three critical incidents based on two face theories proposed by Brown and Levinson (1987) and Ting-Toomey and Kurogi(1998) respectively. Lastly, by focusing on the relationship between the rapport-threatening behavior and the face, this paper intends to cultivate our awareness of face and highlight the harmonious interpersonal relationship between different cultures.

  15. TOPICAL REVIEW: FPA-based infrared thermography as applied to the study of cutaneous perspiration and stimulated vascular response in humans

    Science.gov (United States)

    Vainer, Boris G.

    2005-12-01

    This review gives an overview of focal plane array (FPA)-based infrared (IR) thermography as a powerful research method in the field of physiology and medicine. Comparison of the gained results with the data previously obtained by other authors with other research tools is given. Outer thermoregulatory manifestations displayed by the human organism subjected to whole-body heating (sauna bath) and physical loads (exercise bicycling) are quantitatively analysed. Some details of human body emotional sweating (psycho-physiological effect) are reported. Particular attention is paid to studying active sweat glands as individual objects. All experimental data were obtained with the help of a high-sensitivity (0.03 °C) fast 128 × 128 InAs IR detector-based thermal imaging system operating in the short-wave spectral region (2.5 to 3 µm) and perfectly suiting medical purposes. It is shown that IR thermography makes it possible to overcome limitations inherent to contact measuring means that were traditionally used before in thermal studies. It is also shown that heterogeneous thermograms displayed by organisms with disturbed inner equilibrium can be quantitatively analysed in terms of statistical parameters of related surface-temperature histograms, such as the mean temperature and the standard deviation of temperature (SDT). The increase and the decrease in SDT turned out to be typical of prolonged physical load and subsequent relaxation, and of external whole-body heating, respectively. Explanation of this result based on a hypothesis advanced within the context of the doctrine of human-organism evolution is given. Skin-temperature distribution function accompanying the relaxed organism in normality was found to closely resemble normal-distribution function. Symmetry break down and variation of the shape of this characteristic may serve as an indicator of homeostasis shift and can be used as a quantitative criterion for the latter. A new phenomenon, stable punctate

  16. The Use and Abuse of "Universal Values" in the Danish Cartoon Controversy

    DEFF Research Database (Denmark)

    Rostbøll, Christian Fogh

    's embodiment of these values from the more abstract ideas. To avoid self-contradiction, liberal principles and constitutional norms should not be seen as incontestable aspects of democracy but rather as subject to recursive democratic justification and revision by everyone subject to them. Newcomers should...

  17. The Use and Abuse of ‘Universal Values' in the Danish Cartoon Controversy

    DEFF Research Database (Denmark)

    Rostbøll, Christian F.

    2010-01-01

    . To avoid self-contradiction, liberal principles and constitutional norms should not be seen as incontestable aspects of democracy but rather as subject to recursive democratic justification and revision by everyone subject to them. Newcomers ought to be able to contribute their specific perspectives...

  18. Edge-based compression of cartoon-like images with homogeneous diffusion

    DEFF Research Database (Denmark)

    Mainberger, Markus; Bruhn, Andrés; Weickert, Joachim;

    2011-01-01

    standards such as JBIG and state-of-the-art encoders such as PAQ. When decoding, information outside these encoded data is recovered by solving the Laplace equation, i.e. we inpaint with the steady state of a homogeneous diffusion process. For the discrete reconstruction problem, we prove existence...

  19. Scopus vs WOS as scientific evaluation tools:A comparative analysis based on a testing sample search on the topic of electric vehicles

    Institute of Scientific and Technical Information of China (English)

    WANG; Na; PAN; Yuntao; MA; Zheng; WU; Yishan

    2010-01-01

    Based on a bibliometric analysis in combination with other information analysis methods,this paper compares the different evaluation results on the subject of"electric vehicles"drawn from Web of Science(WOS)and from Scopus.We came to the following conclusions after a careful comparison of these two databases.Firstly,both WOS and Scopus would provide some valid and unique evaluation indicators.Secondly,they showed similar results in terms of evaluating research performance of countries and research organizations involved in the targeted subject fields.In fact,both databases are good for discovering the research trend in general at the macroscopic level.Lastly,we ought to take the disciplinary characteristics,the extent of journal inclusion and resource selection criteria as well as inevitable data errors into full account in making recommendations to policy decision-makers.

  20. The potential of the essential fatty acid-deficient hairless rat as a psoriasis screening model for topical anti-proliferative drugs

    DEFF Research Database (Denmark)

    Jensen, Mette; Groth, L.; Holmer, G.;

    2002-01-01

    with calcipotriol. Dithranol and its coal tar-containing vehicle also showed a reductive effect on epidermal thickness. EFAD hairless rats possess various histological changes resembling psoriasis. These histological changes normalise during treatment with anti-psoriatic drugs as calcipotriol, dithranol and coal......The objective of this study was to establish essential fatty acid deficiency (EFAD) in hairless rats and investigate the potential of this model as a psoriasis screening model by testing the effects of calcipotriol and dithranol on differentiation and proliferation in the epidermis. Hairless rats...... were fed with a fat-free diet lacking linoleic acid. The EFAD condition was established within 8 weeks. In order to ensure that this condition had been established, several parameters were measured and observed, i.e. animal weight, water consumption, transepidermal water loss, clinical skin symptoms...

  1. The potential of the essential fatty acid-deficient hairless rat as a psoriasis screening model for topical anti-proliferative drugs

    DEFF Research Database (Denmark)

    Jensen, M.; Groth, L.; Fullerton, A.;

    2002-01-01

    , histology of the epidermis and fatty acid analysis of serum and skin. Immediately after the EFAD condition had been established, the animals were treated with dithranol ointment or different concentrations of calcipotriol solution. A reduction in epidermal thickness of 15-20% was seen after the treatment...... with calcipotriol. Dithranol and its coal tar-containing vehicle also showed a reductive effect on epidermal thickness. EFAD hairless rats possess various histological changes resembling psoriasis. These histological changes normalise during treatment with anti-psoriatic drugs as calcipotriol, dithranol and coal...

  2. Testing of Continuous Sampling Air-ICP and Mercury Systems as Continuous Emission Monitors at the Diagnostic Instrumentation and Analysis Laboratory; TOPICAL

    International Nuclear Information System (INIS)

    This report has been prepared to document the performance of the continuous sampling reduced-pressure air-ICP-AES (inductively coupled plasma-atomic emission spectroscopy) and mercury-monitor systems developed by Ames Laboratory for use as continuous emission monitors (CEM). This work was funded by the U. S. Department of Energy, Office of Environmental Management, Office of Science and Technology, through the Mixed Waste Focus Area. The purpose of the project is to develop instrumentation and methods for spectroscopic field monitoring applications. During FY00 this included continued work on the development of the continuous sample introduction system and the multi-frequency AOTF-echelle spectrometer, used in conjunction with the reduced-pressure air-ICP-AES system as a multi-metal CEM. The assembly, development, and testing of an echelle spectrometer system for the detection of mercury (Hg) by atomic absorption was also completed during FY00. The continuous sampling system and the multi-metal air-ICP and mercury-monitor CEM systems were tested at Mississippi State University at the Diagnostic Instrumentation and Analysis Laboratory (DIAL) at the end of FY00. This report describes the characteristics and performance of these systems, and the results of the field tests performed at DIAL

  3. Safety and Efficacy of Propranolol in Comparison With Combination of Fentanyl and Ketamine as Premedication in Cataract Surgery Under the Topical Anesthesia.

    Science.gov (United States)

    Fazel, Farhad; Saryazdi, Hamidhajigholam; Rezaei, Leila; Mahboubi, Mohammad

    2015-01-01

    This study evaluated the safety and effects of propranolol as a premedication before cataract surgery and compared them with the usual combination doses of fentanyl and ketamine. Among all reffered patients to Feiz Hospital of Esfahan for cataract surgery, 122 patients between Mar to Sep 2010 were enrolled in this study and randomly allocated into one of the following equal groups: 40 mg propranolol, 2 hours before surgery and combination of 15 mg ketamine and 50 µg fentanyl l. 5 min before surgery. The ability to control of hemodynamic instabilities caused by stress and to gain patients satisfaction was compared between two groups. Also, the efficacy of each premedication to control of hemodynamic changes during surgery were evaluated and compared. No significant differences were seen in the patients satisfaction and controlling of stress induced hemodynamic changes between two groups (P>0.05). However, patients in ketamine + fentanyl group showed more nausea and less pain during and after surgery. Moreover, no significant adverse effects were reported during and after the surgery. Our results demonstrated that propranolol can be used safely as a premedication in cataract surgery in the comparable efficacy to ketamine plus fentanyl premedication. PMID:26153173

  4. Topics in Galois theory

    CERN Document Server

    Serre, Jean-Pierre

    2007-01-01

    This book is based on a course given by the author at Harvard University in the fall semester of 1988. The course focused on the inverse problem of Galois Theory: the construction of field extensions having a given finite group as Galois group. In the first part of the book, classical methods and results, such as the Scholz and Reichardt construction for p-groups, p != 2, as well as Hilbert's irreducibility theorem and the large sieve inequality, are presented. The second half is devoted to rationality and rigidity criteria and their application in realizing certain groups as Galois groups of

  5. Visiones Párodicas: Risas, demonios, jocosidades y caricaturas.

    Directory of Open Access Journals (Sweden)

    Beatriz González.

    2008-08-01

    Full Text Available This article attempts to characterize cartoons by examining topics related to them and parody in four different moments. The frst section addresses the arrival of laughter in the Americas and the present-day territory of Colombia. The relationship between laughter and innocence and maliciousness is noted. In the second section, the demon is presented as a source of evil and as an evangelical teaching tool in the same way that the cartoon is used as a method of teaching. The third section addressses the concepts of Charge and the cartoon in the universal language. It identifes Charge as the literature of manners in New Granada during the nineteenth century The parody of customs and its relationship to Realism in European art and to cartoons is noted. The last section discusses the relationship between cartoon and power: how the myth that cartoons can topple governments becomes, during periods of fun-damentalism, a double-edged weapon for the cartoonist.

  6. The RING for gypsy moth control: Topical application of fragment of its nuclear polyhedrosis virus anti-apoptosis gene as insecticide.

    Science.gov (United States)

    Oberemok, Volodymyr V; Laikova, Kateryna V; Zaitsev, Aleksei S; Gushchin, Vladimir A; Skorokhod, Oleksii A

    2016-07-01

    Numerous studies suggest a cellular origin for the Lymantria dispar multicapsid nuclear polyhedrosis virus (LdMNPV) anti-apoptosis genes IAPs, thus opening a possibility to use the fragments of these genes for modulation of host metabolism. We report here the strong insecticidal and metabolic effect of single-stranded antisense DNA fragment from RING (really interesting new gene) domain of gypsy moth LdMNPV IAP-3 gene: specifically, on reduction of biomass (by 35%) and survival of L. dispar caterpillars. The treatment with this DNA fragment leads to a significantly higher mortality rates of female insects (1.7 fold) accompanied with the signs of apoptosis. Additionally, we show increased expression of host IAP-1, caspase-4 and gelsolin genes in eggs laid by survived females treated with RING DNA fragment accompanied with calcium and magnesium imbalance, indicating that the strong stress reactions and metabolic effects are not confined to treated insects but likely led to apoptosis in eggs too. The proposed new approach for insect pest management, which can be considered as advancement of "microbial pesticides", is based on the application of the specific virus DNA, exploiting the knowledge about virus-pest interactions and putting it to the benefit of mankind. PMID:27265824

  7. The Cartoon Society: Using "The Simpsons" To Teach and Learn Sociology.

    Science.gov (United States)

    Scanlan, Stephen J.; Feinberg, Seth L.

    2000-01-01

    Presents the animated television series "The Simpsons" as a tool to reach undergraduate students by using popular culture to teach sociology. Discusses "The Simpsons" and sociology, provides a sample of the sociological themes embedded within the show, and how to use "The Simpsons." Provides information gleaned from students evaluations. (CMK)

  8. Concept Cartoons Supported Problem Based Learning Method in Middle School Science Classrooms

    Science.gov (United States)

    Balim, Ali Günay; Inel-Ekici, Didem; Özcan, Erkan

    2016-01-01

    Problem based learning, in which events from daily life are presented as interesting scenarios, is one of the active learning approaches that encourages students to self-direct learning. Problem based learning, generally used in higher education, requires students to use high end thinking skills in learning environments. In order to use…

  9. "Clones," Codes, and Conflicts of Interest in Cartooning: Cartoonists and Editors Look at Ethics.

    Science.gov (United States)

    Riffe, Daniel; And Others

    A study examined differences between political cartoonists and op-ed page editors on both traditional ethical issues (such as conflicts of interest) and the special, style-related concerns of editorial cartoonists. Hypotheses proposed were that editors and cartoonists (1) would condemn "cloning" or copying, reflecting an ethical principle…

  10. Learning Topic Models by Belief Propagation

    CERN Document Server

    Zeng, Jia; Liu, Jiming

    2011-01-01

    Latent Dirichlet allocation (LDA) is an important class of hierarchical Bayesian models for probabilistic topic modeling, which attracts worldwide interests and touches many important applications in text mining, computer vision and computational biology. This paper proposes a novel tree-structured factor graph representation for LDA within the Markov random field (MRF) framework, which enables the classic belief propagation (BP) algorithm for exact inference and parameter estimation. Although two commonly-used approximation inference methods, such as variational Bayes (VB) and collapsed Gibbs sampling (GS), have gained great successes in learning LDA, the proposed BP is competitive in both speed and accuracy validated by encouraging experimental results on four large-scale document data sets. Furthermore, the BP algorithm has the potential to become a generic learning scheme for variants of LDA-based topic models. To this end, we show how to learn two typical variants of LDA-based topic models, such as autho...

  11. Selected topics on Hadrons in Nuclei

    CERN Document Server

    Oset, E; Hernandez, E; Ramos, A; Magas, V K; Yamagata-Sekihara, J; Hirenzaki, S; Gamermann, D; Molina, R; Tolos, L; Roca, L

    2011-01-01

    In this talk we report on selected topics on hadrons in nuclei. The first topic is the renormalization of the width of the $\\Lambda(1520)$ in a nuclear medium. This is followed by a short update of the situation of the $\\omega$ in the medium. The investigation of the properties of $\\bar{K}$ in the nuclear medium from the study of the $(K_{flight},p)$ reaction is also addressed, as well as properties of X,Y,Z charmed and hidden charm resonances in a nuclear medium. Finally we address the novel issue of multimeson states.

  12. Corticosteróide tópico oclusivo no tratamento de manifestações gengivais de doenças vesicobolhosas auto-imunes Topical occlusive corticosteroid for the treatment of gingival manifestations of vesicobullous autoimmune diseases

    Directory of Open Access Journals (Sweden)

    Ana Carolina Fragoso Motta

    2006-06-01

    Full Text Available O tratamento das lesões gengivais de doenças vesicobolhosas auto-imunes constitui grande desafio na estomatologia, principalmente pela natureza crônica das lesões. O tratamento sistêmico é necessário no controle das apresentações mais graves; entretanto, quando possível, o tratamento tópico é preferível. Este artigo descreve uma técnica oclusiva para aplicação de corticosteróide tópico que tem demonstrado ser eficaz no controle dessas lesões, sobretudo em pacientes com manifestações exclusivamente gengivais.Management of gingival lesions of vesicobullous autoimmune diseases is one the main challenges to oral medicine, primarily because of their chronic nature. Systemic therapy is required in most severe lesions, however, whenever feasible, topic corticosteroid therapy is preferred. This article describes a technique to provide topical occlusive corticotherapy that has shown to be effective in controlling these lesions, especially in patients exclusively with gingival lesions.

  13. Cultura e política nos quadrinhos de Henfil Culture and politics in Henfil's cartoons

    Directory of Open Access Journals (Sweden)

    Maria da Conceição Francisca Pires

    2006-01-01

    Full Text Available O artigo apresenta uma incursão pelo universo discursivo dos polêmicos personagens "Fradins", criados pelo cartunista Henfil. A intenção é colocar em relevo a construção de uma crítica política e de costumes que colocou em xeque, por um lado, o cristianismo oficioso das elites políticas e religiosas e, por outro, os simulacros sociais. No caso em questão não se trata apenas da crítica à devoção, mas especificamente a devoção ao poder. Defendo a premissa de que por intermédio do grotesco e do fantástico, em conjunto com a ironia e a carnavalização, Henfil desmistificou as deidades políticas e religiosas, substituindo-as pela dúvida e colocando-as lado a lado com o ridículo. Deste modo, o humor henfiliano representou um esforço de resistência, ao mesmo tempo em que contribuiu para a luta política contra a ditadura militar.The article presents a incursion for the discursive universe of the controversial characters "Fradins", created by the cartunist Henfil. The intention is pointing out, on one hand, the curbed politics and customs construction, and, on the other hand, the religious elites obliging Christianity politics as well as the social simulacra. The studied case is not only about the critical devotion, but specifically about the devotion to the power. I defend the premise that, by means of grotesques and fantastic features, in irony and carnavalization scenario, Henfil has demystified the religious and political deities, replacing them with the doubt and placing them side by side with ridicule. In this way, the henfilianian mood represents a resistance effort, at the same time that contributes for the political fight against the military dictatorship.

  14. Analysis and Enlightenment of Packaging Design of Famous International Cartoon Derivatives%国际知名动漫衍生品包装设计探析及启示

    Institute of Scientific and Technical Information of China (English)

    魏武

    2012-01-01

    According to analysis of the packaging design of famous international cartoon derivatives,combined with the packaging design it discussed in detail three aspects of cartoon character features,characteristics of anime derivatives products and different psychological needs of audience.Then combined with the market situation of domestic cartoon derivatives,it analyzed the enlightenment of famous international cartoon derivatives packaging on product development diversification,market target and packaging design elements.%针对一些国际知名动漫衍生品的包装设计进行了解析,分别从动漫角色的性格特征、动漫衍生品的产品特征以及受众的不同心理需求3个方面结合包装设计进行了论述。进而结合国内动漫衍生品市场现状,分析了国际知名动漫衍生品包装对产品开发多元化、市场针对性以及包装设计要素等方面所带来的启示。

  15. 他们的画像——杭州首届中国国际漫画节手札%First China International Cartoon Festival Held in Hangzhou

    Institute of Scientific and Technical Information of China (English)

    杨小亥

    2012-01-01

    Some people do not think cartoon is art in its traditional sense although they are willing to admit that the art does inspire humor and open people's eye to the funny side of everyday life. The first China International Cartoon Festival held in Hangzhou from November 4 through 6, 2011 is widely considered a successful at- tempt to have changed some people's definition of cartoon art. The festival was held in a series of venues: the exhibition was held at the World Trade Center, the award-issuing ceremony at Hangzhou Grand Theater, a forum of cartoon artists and scholars at Westhrook Wetland. The pioneering event enabled visitors to appreciate the,%在王尔德的小说《道连.格雷的画像》中,一个情节让人难忘——艺术家霍华德对他倾注了感情的漫画对象道连.格雷说:"你已经成了我看不见的理想的可见的化身。"在很多人眼里,漫画等于幽默、调侃、生活调剂品,而非正统意义上的艺术形态。

  16. Emerging topics in FXTAS

    DEFF Research Database (Denmark)

    Hall, Deborah A; Birch, Rachael C; Anheim, Mathieu;

    2014-01-01

    This paper summarizes key emerging issues in fragile X-associated tremor/ataxia syndrome (FXTAS) as presented at the First International Conference on the FMR1 Premutation: Basic Mechanisms & Clinical Involvement in 2013....

  17. Clindamycin and Benzoyl Peroxide Topical

    Science.gov (United States)

    ... benzoyl peroxide works by killing the bacteria that cause acne. ... E-Mycin, Erythrocin) and other topical medications for acne. Your doctor ... colitis (a condition which causes swelling and sores in the lining of the ...

  18. Cartoon toys combine feasibility%动漫玩具结合可行性浅谈

    Institute of Scientific and Technical Information of China (English)

    黄练基

    2015-01-01

    玩具动画,顾名思义是以带动玩具衍生品销售为目的所摄制的一类动画,要将动画与玩具有机地巧妙地结合,不能只是一种单纯的撮合或简单地植入,而需要形成一套系统的良性的双赢的互动结合模式.%Toys animation, just as its name implies is to drive the toy derivatives for the sale of a class of film animation, animation and toys to organicaly combined ably, not just a simple fix or simply implants, and need to form a benign win-win interactive model of the system.

  19. Water: A Topic for All Sciences

    Science.gov (United States)

    Davies, Malonne I.; Seimears, C. Matt

    2008-01-01

    The authors illustrate an effective lesson-planning technique known as unpacking for the broad topic of water. Interconnections among science disciplines are shown for numerous possible subtopics. Two lesson sets are included, the first dealing with properties of water and the second dealing with water as a resource. (Contains 1 table and 4…

  20. Do scientists trace hot topics?

    OpenAIRE

    Tian Wei; Menghui Li; Chensheng Wu; Xiao-Yong Yan; Ying Fan; Zengru Di; Jinshan Wu

    2013-01-01

    Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of papers belonging to the field. This indicates that scientists generally do follow hot topics. However, there are qualitative differences among scientists from various countries,...

  1. Key Topics in Sports Medicine

    OpenAIRE

    Amir Ali Narvani; Panagiotis Thomas; Burce Lynn

    2006-01-01

    Key Topics in Sports Medicine is a single quick reference source for sports and exercise medicine. It presents the essential information from across relevant topic areas, and includes both the core and emerging issues in this rapidly developing field. It covers: 1) Sports injuries, rehabilitation and injury prevention, 2) Exercise physiology, fitness testing and training, 3) Drugs in sport, 4) Exercise and health promotion, 5) Sport and exercise for special and clinical populations, 6) The ps...

  2. Topics of Bioengineering in Wikipedia

    Directory of Open Access Journals (Sweden)

    Vassia Atanassova

    2009-10-01

    Full Text Available The present report aims to give a snapshot of how topics from the field of bioengineering (bioinformatics, bioprocess systems, biomedical engineering, biotechnology, etc. are currently covered in the free electronic encyclopedia Wikipedia. It also offers insights and information about what Wikipedia is, how it functions, how and when to cite Wikipedian articles, if necessary. Several external wikis, devoted to topics of bioengineering, are also listed and reviewed.

  3. Current topics in photovoltaics

    International Nuclear Information System (INIS)

    This book contains papers on current research in photovoltaics. Areas include: outdoor spectral odor radiation variations and their relationship to photovoltaic device performance, numerical modeling for analysis and design of solar cells, radiation damage mechanisms in GaAs and Si solar cells, and health and safety issues in the manufacturing of photovoltaic cells

  4. Sarcoidosis - Main Topic

    Directory of Open Access Journals (Sweden)

    Nilgün Solak Tekin

    2012-09-01

    Full Text Available Sarcoidosis is a multisystemic, inflammatory disease of unknown etiology that is characterized by noncaseating granulomas. Approximately, one-third of the patients with systemic sarcoidosis are observed cutaneous manifestations of different morphologies. Skin sarcoidosis have extremely heterogeneous clinical picture, so it is defined as “The Great Imitator” or “clinical chameleon”.

  5. Topics in Supergravity Phenomenology

    CERN Document Server

    Dhuria, Mansi

    2014-01-01

    In the first part of the review article, we discuss the possibility of realizing "mu-split-like SUSY" scenario from a phenomenological model, which we show could be realizable locally as the large volume limit of a type IIB Swiss-Cheese Calabi-Yau orientifold involving a mobile space-time filling D3-brane localized at a nearly special Lagrangian three-cycle embedded in the "big" divisor and multiple fluxed stacks of space-time filling D7-branes wrapping the same "big" divisor. We show that the mass of one of the Higgs doublets can be produced to be of the order of 125 GeV whereas other Higgs as well as higgsino mass parameter to be very heavy- the "mu-split-like SUSY" scenario. Then we discuss the role of the heavy squarks/sleptons and the light Higgs in (i) obtaining long-lived gluinos (ii) in verifying that the NLSPs (squarks/sleptons/neutralino) decay into the LSP (gravitino) respects the BBN constraints with the lifetime of the LSP (gravitino) coming out to be of the order or larger than the age of the un...

  6. Illustrative EDOF topics in Fourier optics

    Science.gov (United States)

    George, Nicholas; Chen, Xi; Chi, Wanli

    2011-10-01

    In this talk we present a series of illustrative topics in Fourier Optics that are proving valuable in the design of EDOF camera systems. They are at the level of final examination problems that have been made solvable by a student or professoi having studied from one of Joseph W. Goodman's books---our tribute for his 75fr year. As time permits, four illustrative topics are l) Electromagnetic waves and Fourier optics;2) The perfect lens; 3) Connection between phase delay and radially varying focal length in an asphere and 4) tailored EDOF designs.

  7. APT accelerator. Topical report

    International Nuclear Information System (INIS)

    The Accelerator Production of Tritium (APT) project, sponsored by Department of Energy Defense Programs (DOE/DP), involves the preconceptual design of an accelerator system to produce tritium for the nation's stockpile of nuclear weapons. Tritium is an isotope of hydrogen used in nuclear weapons, and must be replenished because of radioactive decay (its half-life is approximately 12 years). Because the annual production requirements for tritium has greatly decreased since the end of the Cold War, an alternative approach to reactors for tritium production, based on a linear accelerator, is now being seriously considered. The annual tritium requirement at the time this study was undertaken (1992-1993) was 3/8 that of the 1988 goal, usually stated as 3/8-Goal. Continued reduction in the number of weapons in the stockpile has led to a revised (lower) production requirement today (March, 1995). The production requirement needed to maintain the reduced stockpile, as stated in the recent Nuclear Posture Review (summer 1994) is approximately 3/16-Goal, half the previous level. The Nuclear Posture Review also requires that the production plant be designed to accomodate a production increase (surge) to 3/8-Goal capability within five years, to allow recovery from a possible extended outage of the tritium plant. A multi-laboratory team, collaborating with several industrial partners, has developed a preconceptual APT design for the 3/8-Goal, operating at 75% capacity. The team has presented APT as a promising alternative to the reactor concepts proposed for Complex-21. Given the requirements of a reduced weapons stockpile, APT offers both significant safety, environmental, and production-fexibility advantages in comparison with reactor systems, and the prospect of successful development in time to meet the US defense requirements of the 21st Century

  8. APT accelerator. Topical report

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence, G.; Rusthoi, D. [comp.] [ed.

    1995-03-01

    The Accelerator Production of Tritium (APT) project, sponsored by Department of Energy Defense Programs (DOE/DP), involves the preconceptual design of an accelerator system to produce tritium for the nation`s stockpile of nuclear weapons. Tritium is an isotope of hydrogen used in nuclear weapons, and must be replenished because of radioactive decay (its half-life is approximately 12 years). Because the annual production requirements for tritium has greatly decreased since the end of the Cold War, an alternative approach to reactors for tritium production, based on a linear accelerator, is now being seriously considered. The annual tritium requirement at the time this study was undertaken (1992-1993) was 3/8 that of the 1988 goal, usually stated as 3/8-Goal. Continued reduction in the number of weapons in the stockpile has led to a revised (lower) production requirement today (March, 1995). The production requirement needed to maintain the reduced stockpile, as stated in the recent Nuclear Posture Review (summer 1994) is approximately 3/16-Goal, half the previous level. The Nuclear Posture Review also requires that the production plant be designed to accomodate a production increase (surge) to 3/8-Goal capability within five years, to allow recovery from a possible extended outage of the tritium plant. A multi-laboratory team, collaborating with several industrial partners, has developed a preconceptual APT design for the 3/8-Goal, operating at 75% capacity. The team has presented APT as a promising alternative to the reactor concepts proposed for Complex-21. Given the requirements of a reduced weapons stockpile, APT offers both significant safety, environmental, and production-fexibility advantages in comparison with reactor systems, and the prospect of successful development in time to meet the US defense requirements of the 21st Century.

  9. Topics in soliton theory

    CERN Document Server

    Carroll, RW

    1991-01-01

    When soliton theory, based on water waves, plasmas, fiber optics etc., was developing in the 1960-1970 era it seemed that perhaps KdV (and a few other equations) were really rather special in the set of all interesting partial differential equations. As it turns out, although integrable systems are still special, the mathematical interaction of integrable systems theory with virtually all branches of mathematics (and with many currently developing areas of theoretical physics) illustrates the importance of this area. This book concentrates on developing the theme of the tau function. KdV and K

  10. Quantum mechanics selected topics

    CERN Document Server

    Perelomov, Askold Mikhailovich

    1998-01-01

    It can serve as a good supplement to any quantum mechanics textbook, filling the gap between standard textbooks and higher-level books on the one hand and journal articles on the other. This book provides a detailed treatment of the scattering theory, multidimensional quasi-classical approximation, non-stationary problems for oscillators and the theory of unstable particles. It will be useful for postgraduate students and researchers who wish to find new, interesting information hidden in the depths of non-relativistic quantum mechanics.

  11. Mapping the evolution of research topics using ATM and SNA

    Institute of Scientific and Technical Information of China (English)

    Chunlei; YE

    2014-01-01

    Purpose:This paper introduces an analysis framework for tracking the evolution of research topics at the selected topics level,covering a research topic’s evolution trend,evolution path and its content changes over time.Design/methodology/approach:After the topics were recovered by the author-topic model,we first built the keyword-topic co-occurrence network to track the dynamics of topic trends.Then a single-mode network was constructed with each node representing a topic and edge indicating the relationship between topics.It was used to illustrate the evolution path and content changes of research topics.A case study was conducted on the digital library research in China to verify the effectiveness of the analysis framework.Findings:The experimental results show that this analysis framework can be used to track evolution of research topics at a micro level and using social network analysis method can help understand research topics’evolution paths and content changes with the passage of time.Research limitations:Using the analysis framework will produce limited results when examining unstructured data such as social media data.In addition,the effectiveness of the framework introduced in this paper needs to be verified with more research topics in information science and in more scientific fields.Practical implications:This analysis framework can help scholars and researchers map research topics’evolution process and gain insights into how a field’s topics have evolved over time.Originality/value:Tbe analysis framework used in this study can help reveal more micro evolution details.The index to measure topic association strength defined in this paper reflects both similarity and dissimilarity between topics,which belps better understand research topics’evolution paths and content changes.

  12. Topics in quantum gravity

    International Nuclear Information System (INIS)

    Quantum gravity is an attempt to unify general relativity with quantum mechanics which are the two highly successful fundamental theories of theoretical physics. The main difficulty in this unification arises from the fact that, while general relativity describes gravity as a macroscopic geometrical theory, quantum mechanics explains microscopic phenomena. As a further complication, not only do both theories describe different scales but also their philosophical ramifications and the mathematics used to describe them differ in a dramatic way. Consequently, one possible starting point of an attempt at a unification is quantum mechanics, i.e. particle physics, and try to incorporate gravitation. This pathway has been chosen by particle physicists which led to string theory. On the other hand, loop quantum gravity (LQG) chooses the other possibility, i.e. it takes the geometrical aspects of gravity seriously and quantizes geometry. The first part of this thesis deals with a generalization of loop quantum cosmology (LQC) to toroidal topologies. LQC is a quantization of homogenous solutions of Einstein's field equations using tools from LQG. First the general concepts of closed topologies is introduced with special emphasis on Thurston's theorem and its consequences. It is shown that new degrees of freedom called Teichmueller parameters come into play and their dynamics can be described by a Hamiltonian. Several numerical solutions for a toroidal universe are presented and discussed. Following the guidelines of LQG this dynamics are rewritten using the Ashtekar variables and numerical solutions are shown. However, in order to find a suitable Hilbert space a canonical transformation must be performed. On the other hand this transformation makes the quantization of geometrical quantities less tractable such that two different ways are presented. It is shown that in both cases the spectrum of such geometrical operators depends on the initial value problem. Furthermore, we

  13. Topics in quantum gravity

    Energy Technology Data Exchange (ETDEWEB)

    Lamon, Raphael

    2010-06-29

    Quantum gravity is an attempt to unify general relativity with quantum mechanics which are the two highly successful fundamental theories of theoretical physics. The main difficulty in this unification arises from the fact that, while general relativity describes gravity as a macroscopic geometrical theory, quantum mechanics explains microscopic phenomena. As a further complication, not only do both theories describe different scales but also their philosophical ramifications and the mathematics used to describe them differ in a dramatic way. Consequently, one possible starting point of an attempt at a unification is quantum mechanics, i.e. particle physics, and try to incorporate gravitation. This pathway has been chosen by particle physicists which led to string theory. On the other hand, loop quantum gravity (LQG) chooses the other possibility, i.e. it takes the geometrical aspects of gravity seriously and quantizes geometry. The first part of this thesis deals with a generalization of loop quantum cosmology (LQC) to toroidal topologies. LQC is a quantization of homogenous solutions of Einstein's field equations using tools from LQG. First the general concepts of closed topologies is introduced with special emphasis on Thurston's theorem and its consequences. It is shown that new degrees of freedom called Teichmueller parameters come into play and their dynamics can be described by a Hamiltonian. Several numerical solutions for a toroidal universe are presented and discussed. Following the guidelines of LQG this dynamics are rewritten using the Ashtekar variables and numerical solutions are shown. However, in order to find a suitable Hilbert space a canonical transformation must be performed. On the other hand this transformation makes the quantization of geometrical quantities less tractable such that two different ways are presented. It is shown that in both cases the spectrum of such geometrical operators depends on the initial value problem

  14. The Virtual Robotics Laboratory; TOPICAL

    International Nuclear Information System (INIS)

    The growth of the Internet has provided a unique opportunity to expand research collaborations between industry, universities, and the national laboratories. The Virtual Robotics Laboratory (VRL) is an innovative program at Oak Ridge National Laboratory (ORNL) that is focusing on the issues related to collaborative research through controlled access of laboratory equipment using the World Wide Web. The VRL will provide different levels of access to selected ORNL laboratory secondary education programs. In the past, the ORNL Robotics and Process Systems Division has developed state-of-the-art robotic systems for the Army, NASA, Department of Energy, Department of Defense, as well as many other clients. After proof of concept, many of these systems sit dormant in the laboratories. This is not out of completion of all possible research topics. but from completion of contracts and generation of new programs. In the past, a number of visiting professors have used this equipment for their own research. However, this requires that the professor, and possibly his/her students, spend extended periods at the laboratory facility. In addition, only a very exclusive group of faculty can gain access to the laboratory and hardware. The VRL is a tool that enables extended collaborative efforts without regard to geographic limitations

  15. Science in cartoons

    CERN Multimedia

    CERN Bulletin

    Normal.dotm 0 0 1 41 238 cern 1 1 292 12.0 0 false 18 pt 18 pt 0 0 false false false /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman"; mso-ascii-font-family:Cambria; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Cambria; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Normal.dotm 0 0 1 43 246 cern 2 1 302 12.0 0 false 18 pt 18 pt 0 0 false false false /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; m...

  16. Research of human hair animation generation technology in cartoon%一种卡通动画中人物头发运动生成技术研究

    Institute of Scientific and Technical Information of China (English)

    欧训勇

    2014-01-01

    This paper introduces a new hybrid technique for human hair animation in cartoon , which allows the animators to create attractive and controllable hair animations without having to draw everything by hand except a sparse set of keyframes. This method demonstrates how to give a cel-animation character accentuated hair motion. The novelty of this approach is that we neither simply interpolate the key frames nor generate the movement of the hair only using physical simulations. From a small number of rough sketches we prepare key frames that are used as indicators of hair motion. The hair movements are created based on a hair motion database built from physical simulations custom-designed by the animator. Hair animations with constraints from the key frames can be generated in two stages: a matching process to search for the desired motion sequences from the database and then smoothly connect them; the discrepancies between the database sequences and the key frames are interpolated throughout the animation using transition function.%介绍了一种新的卡通动画中人物头发运动的混合技术,使动画师们能方便地创作出有吸引力和可控性的头发运动效果,而不需要手工对头发运动表现过程进行逐帧绘制,仅设置好所需的一些关键帧画面。该技术方法演示如何根据给出的手绘卡通人物角色动作配以相应的头发运动效果。这种方法的新颖之处是,既不是简单地插入关键帧来获得头发运动效果,也不是通过物理模拟的方式来生成头发飘逸的动画,而是从动画师预先准备好的少量的作为关键帧草图的头发运动效果,建立物理模拟动画数据库,根据此数据库中头发的运动效果来创建出特定头发运动动画。此方法生成的头发动画分两个阶段完成,首先是在数据库中搜索对应的运动效果画面,然后顺利连接;其次数据库序列的关键帧之间的过渡帧由在动画中运

  17. Hot Topic Talk 4

    Science.gov (United States)

    Hosten, Onur

    2016-05-01

    I will focus on our experiments with cold atoms highlighting some of the most recent developments in the prospect of using quantum entanglement to improve the precision of atomic and optical sensors. The first part of the talk will describe the generation of 20 dB spin-squeezed states of half a million 87Rb atoms inside of an optical cavity. The second part will describe the experimental demonstration of a new concept we call quantum phase magnification. The demonstrated 20 dB squeezing enables a 100-fold reduction in averaging time or a 100-fold reduction in atom numbers to achieve a given sensing precision. As part of this work we show an atomic clock operating 10 dB beyond the classical limit. Some of the states prepared in these experiments possess in excess of 680 atom entanglement. The quantum phase magnification experiment shows that detection noise levels below the standard quantum limit is in fact not a requirement to realize the benefits of the intrinsic sensitivity provided by exotic quantum states. Here, optical cavity-aided effective interactions between atoms magnify signals to-be-measured to levels that can easily be detected with a rather inefficient fluorescence imaging system. The method relaxes stringent detection requirements which have been the main bottleneck in quantum metrology experiments, and can also be implemented in physical platforms other than cold atom-cavity systems.

  18. Organic solvent topical report

    Energy Technology Data Exchange (ETDEWEB)

    COWLEY, W.L.

    1999-05-13

    This report provides the basis for closing the organic solvent safety issue. Sufficient information is presented to conclude that risk posed by an organic solvent fire is within risk evaluation guidelines. This report updates information contained in Analysis of Consequences of Postulated Solvent Fires in Hanford Site Waste Tanks. WHC-SD-WM-CN-032. Rev. 0A (Cowley et al. 1996). However, this document will not replace Cowley et al (1996) as the primary reference for the Basis for Interim Operation (BIO) until the recently submitted BIO amendment (Hanson 1999) is approved by the US Department of Energy. This conclusion depends on the use of controls for preventing vehicle fuel fires and for limiting the use of flame cutting in areas where hot metal can fall on the waste surface.The required controls are given in the Tank Waste Remediation System Technical Safety Requirements (Noorani 1997b). This is a significant change from the conclusions presented in Revision 0 of this report. Revision 0 of this calcnote concluded that some organic solvent fire scenarios exceeded risk evaluation guidelines, even with controls imposed.

  19. Organic solvent topical report

    International Nuclear Information System (INIS)

    This report provides the basis for closing the organic solvent safety issue. Sufficient information is presented to conclude that risk posed by an organic solvent fire is within risk evaluation guidelines. This report updates information contained in Analysis of Consequences of Postulated Solvent Fires in Hanford Site Waste Tanks. WHC-SD-WM-CN-032. Rev. 0A (Cowley et al. 1996). However, this document will not replace Cowley et al (1996) as the primary reference for the Basis for Interim Operation (BIO) until the recently submitted BIO amendment (Hanson 1999) is approved by the US Department of Energy. This conclusion depends on the use of controls for preventing vehicle fuel fires and for limiting the use of flame cutting in areas where hot metal can fall on the waste surface.The required controls are given in the Tank Waste Remediation System Technical Safety Requirements (Noorani 1997b). This is a significant change from the conclusions presented in Revision 0 of this report. Revision 0 of this calcnote concluded that some organic solvent fire scenarios exceeded risk evaluation guidelines, even with controls imposed

  20. Topics in Collider Physics

    International Nuclear Information System (INIS)

    It is an exciting time for high energy physics. Several experiments are currently exploring uncharted terrain; the next generation of colliders will begin operation in the coming decade. These experiments will together help us understand some of the most puzzling issues in particle physics: the mechanism of electroweak symmetry breaking and the generation of flavor physics. It is clear that the primary goal of theoretical particle physics in the near future is to support and guide this experimental program. These tasks can be accomplished in two ways: by developing experimental signatures for new models which address outstanding problems, and by improving Standard Model predictions for precision observables. We present here several results which advance both of these goals. We begin with a study of non-commutative field theories. It has been suggested that TeV-scale non-commutativity could explain the origin of CP violation in the SM. We identify several distinct signatures of non-commutativity in high energy processes. We also demonstrate the one-loop quantum consistency of a simple spontaneously broken non-commutative U(1) theory; this result is an important preface to any attempt to embed the SM within a non-commutative framework. We then investigate the phenomenology of extra-dimensional theories, which have been suggested recently as solutions to the hierarchy problem of particle physics. We first examine the implications of allowing SM fields to propagate in the full five-dimensional spacetime of the Randall-Sundrum model, which solves the hierarchy problem via an exponential ''warping'' of the Planck scale induced by a five-dimensional anti de-Sitter geometry. In an alternative extra-dimensional theory, in which all SM fields are permitted to propagate in flat extra dimensions, we show that properties of the Higgs boson are significantly modified. Finally, we discuss the next-to-next-to leading order QCD corrections to the dilepton rapidity distribution in

  1. Intelligent Topical Sentiment Analysis for the Classification of E-Learners and Their Topics of Interest

    Directory of Open Access Journals (Sweden)

    M. Ravichandran

    2015-01-01

    Full Text Available Every day, huge numbers of instant tweets (messages are published on Twitter as it is one of the massive social media for e-learners interactions. The options regarding various interesting topics to be studied are discussed among the learners and teachers through the capture of ideal sources in Twitter. The common sentiment behavior towards these topics is received through the massive number of instant messages about them. In this paper, rather than using the opinion polarity of each message relevant to the topic, authors focus on sentence level opinion classification upon using the unsupervised algorithm named bigram item response theory (BIRT. It differs from the traditional classification and document level classification algorithm. The investigation illustrated in this paper is of threefold which are listed as follows: (1 lexicon based sentiment polarity of tweet messages; (2 the bigram cooccurrence relationship using naïve Bayesian; (3 the bigram item response theory (BIRT on various topics. It has been proposed that a model using item response theory is constructed for topical classification inference. The performance has been improved remarkably using this bigram item response theory when compared with other supervised algorithms. The experiment has been conducted on a real life dataset containing different set of tweets and topics.

  2. Intelligent topical sentiment analysis for the classification of e-learners and their topics of interest.

    Science.gov (United States)

    Ravichandran, M; Kulanthaivel, G; Chellatamilan, T

    2015-01-01

    Every day, huge numbers of instant tweets (messages) are published on Twitter as it is one of the massive social media for e-learners interactions. The options regarding various interesting topics to be studied are discussed among the learners and teachers through the capture of ideal sources in Twitter. The common sentiment behavior towards these topics is received through the massive number of instant messages about them. In this paper, rather than using the opinion polarity of each message relevant to the topic, authors focus on sentence level opinion classification upon using the unsupervised algorithm named bigram item response theory (BIRT). It differs from the traditional classification and document level classification algorithm. The investigation illustrated in this paper is of threefold which are listed as follows: (1) lexicon based sentiment polarity of tweet messages; (2) the bigram cooccurrence relationship using naïve Bayesian; (3) the bigram item response theory (BIRT) on various topics. It has been proposed that a model using item response theory is constructed for topical classification inference. The performance has been improved remarkably using this bigram item response theory when compared with other supervised algorithms. The experiment has been conducted on a real life dataset containing different set of tweets and topics.

  3. Topical Structure in Arabic-English Interlanguage.

    Science.gov (United States)

    Fakhri, Ahmed

    A study compared the topical structure (TS) of Arabic and English in order to determine whether Arab learners of English as a Second Language (ESL) transfer potential differences between Arabic and English in their English writing, or whether they use an altogether different TS indicative of developmental factors. Four sets of data were compared…

  4. Seven topics in functional magnetic resonance imaging.

    Science.gov (United States)

    Bandettini, Peter A

    2009-09-01

    Functional MRI (fMRI) is a non-invasive brain imaging methodology that started in 1991 and allows human brain activation to be imaged at high resolution within only a few minutes. Because it has extremely high sensitivity, is relatively easy to implement, and can be performed on most standard clinical MRI scanners. It continues to grow at an explosive rate throughout the world. Over the years, at any given time, fMRI has been defined by only a handful of major topics that have been the focus of researchers using and developing the methodology. In this review, I attempt to take a snapshot of the field of fMRI as it is in mid-2009 by discussing the seven topics that I feel are most on the minds of fMRI researchers. The topics are, in no particular order or grouping: (1) Clinical impact, (2) Utilization of individual functional maps, (3) fMRI signal interpretation, (4) Pattern effect mapping and decoding, (5) Endogenous oscillations, (6) MRI technology, and (7) Alternative functional contrast mechanisms. Most of these topics are highly interdependent, each advancing as the others advance. While most fMRI involves applications towards clinical or neuroscience questions, all applications are fundamentally dependent on advances in basic methodology as well as advances in our understanding of the relationship between neuronal activity and fMRI signal changes. This review neglects almost completely an in-depth discussion of applications. Rather the discussions are on the methods and interpretation.

  5. Topics on electricity trade

    International Nuclear Information System (INIS)

    being unable to fulfil the commitments made on the spot market. The disclosed cost of using the regulating power market is a quadratic function of the amount of regulation. This asymmetric cost may encourage bidders with fluctuating production to be more strategic in their way of bidding on the spot market. By using such strategies the extra costs (for e.g. wind power) needed to counter unpredictable fluctuations may be limited. The fourth paper applies the findings in the previous paper to show how a supplier with a 'controllable' production will make strategic bids on the power exchange - in this case a heat pump. The fifth paper discusses the design of the regulating power market and what the choice of design means for suppliers with fluctuating production, e.g. wind turbines. It is found that not only does the accuracy of the wind prediction influence the use of the power exchange, but the structure of the power exchange itself may also play an important role. Several studies of the northern European electricity liberalisation have concluded that developments of a liberalised electricity market and cross border trade can be of benefit for the consumers and bring along a global environmental improvement. All these studies have assumed that a perfect competitive electricity market can be obtained. A number of imperfections, which inevitably will arise, have not been taken into account, - at least in the transition period. These imperfections can be technical, economic or tradition-bound, but may have political characteristics as well. The sixth paper in this thesis surveys those market imperfections which are most likely to appear. Market imperfections can, for example, have structural or political characteristics that imply non-optimal competitive behaviour, e.g., the means to achieve political goals may hinder the desirable effects of the liberalisation. This can, for example, come from the creation of suitable arrangements for survival and enlargement of renewable

  6. Topics on electricity trade

    Energy Technology Data Exchange (ETDEWEB)

    Skytte, K.

    2001-07-01

    being unable to fulfil the commitments made on the spot market. The disclosed cost of using the regulating power market is a quadratic function of the amount of regulation. This asymmetric cost may encourage bidders with fluctuating production to be more strategic in their way of bidding on the spot market. By using such strategies the extra costs (for e.g. wind power) needed to counter unpredictable fluctuations may be limited. The fourth paper applies the findings in the previous paper to show how a supplier with a 'controllable' production will make strategic bids on the power exchange - in this case a heat pump. The fifth paper discusses the design of the regulating power market and what the choice of design means for suppliers with fluctuating production, e.g. wind turbines. It is found that not only does the accuracy of the wind prediction influence the use of the power exchange, but the structure of the power exchange itself may also play an important role. Several studies of the northern European electricity liberalisation have concluded that developments of a liberalised electricity market and cross border trade can be of benefit for the consumers and bring along a global environmental improvement. All these studies have assumed that a perfect competitive electricity market can be obtained. A number of imperfections, which inevitably will arise, have not been taken into account, - at least in the transition period. These imperfections can be technical, economic or tradition-bound, but may have political characteristics as well. The sixth paper in this thesis surveys those market imperfections which are most likely to appear. Market imperfections can, for example, have structural or political characteristics that imply non-optimal competitive behaviour, e.g., the means to achieve political goals may hinder the desirable effects of the liberalisation. This can, for example, come from the creation of suitable arrangements for survival and enlargement of

  7. Topics on electricity trade

    Energy Technology Data Exchange (ETDEWEB)

    Skytte, K.

    2001-07-01

    being unable to fulfil the commitments made on the spot market. The disclosed cost of using the regulating power market is a quadratic function of the amount of regulation. This asymmetric cost may encourage bidders with fluctuating production to be more strategic in their way of bidding on the spot market. By using such strategies the extra costs (for e.g. wind power) needed to counter unpredictable fluctuations may be limited. The fourth paper applies the findings in the previous paper to show how a supplier with a 'controllable' production will make strategic bids on the power exchange - in this case a heat pump. The fifth paper discusses the design of the regulating power market and what the choice of design means for suppliers with fluctuating production, e.g. wind turbines. It is found that not only does the accuracy of the wind prediction influence the use of the power exchange, but the structure of the power exchange itself may also play an important role. Several studies of the northern European electricity liberalisation have concluded that developments of a liberalised electricity market and cross border trade can be of benefit for the consumers and bring along a global environmental improvement. All these studies have assumed that a perfect competitive electricity market can be obtained. A number of imperfections, which inevitably will arise, have not been taken into account, - at least in the transition period. These imperfections can be technical, economic or tradition-bound, but may have political characteristics as well. The sixth paper in this thesis surveys those market imperfections which are most likely to appear. Market imperfections can, for example, have structural or political characteristics that imply non-optimal competitive behaviour, e.g., the means to achieve political goals may hinder the desirable effects of the liberalisation. This can, for example, come from the creation of suitable arrangements for survival and enlargement of

  8. Selecting a Topic in Public Speaking

    Institute of Scientific and Technical Information of China (English)

    刘玉霞

    2013-01-01

    The first step in speechmaking is choosing a topic, which will decide the success of the speech. In the paper, we are go⁃ing to discuss how to select a topic in public speaking, and we’ll mainly talk about the following: the speaker, the occasion and the audience, selecting a topic, specific methods for choosing a topic and available topics.

  9. Main technical topics in 1999

    International Nuclear Information System (INIS)

    This Safety Authority annual report strives to present current organizational provisions and future trends in nuclear safety supervision in France and to describe the most outstanding occurrences during the past year. A first part presents nine documents concerning the main topics of 1999: aging of nuclear installations, the Offsite Emergency Plans (PPI), the impact of nuclear activities on man and the environment, the criticality hazards, EDF in 1999, the EPR project, the Andra in 1999, the transport incidents, the nuclear safety in eastern Europe. The second part presents the missions and actions of the Nuclear Installations Safety in the domains of the liabilities, the organization of the nuclear safety control, the regulations of the INB, the public information, the international relations, the crisis management, the radioactive materials transportation, the radioactive wastes. The equipment, the radiation protection and the exploitation of the pressurized water reactors are also treated just as the experimental reactors, the fuel cycle installations and the the nuclear installations dismantling. (A.L.B.)

  10. topicmodels: An R Package for Fitting Topic Models

    Directory of Open Access Journals (Sweden)

    Bettina Grun

    2011-05-01

    Full Text Available Topic models allow the probabilistic modeling of term frequency occurrences in documents. The fitted model can be used to estimate the similarity between documents as well as between a set of specified keywords using an additional layer of latent variables which are referred to as topics. The R package topicmodels provides basic infrastructure for fitting topic models based on data structures from the text mining package tm. The package includes interfaces to two algorithms for fitting topic models: the variational expectation-maximization algorithm provided by David M. Blei and co-authors and an algorithm using Gibbs sampling by Xuan-Hieu Phan and co-authors.

  11. Topical agents in burn care

    Directory of Open Access Journals (Sweden)

    Momčilović Dragan

    2002-01-01

    Full Text Available Introduction Understanding of fluid shifts and recognition of the importance of early and appropriate fluid replacement therapy have significantly reduced mortality in the early post burn period. After the bum patient successfully passes the resuscitation period, the burn wound represents the greatest threat to survival. History Since the dawn of civilization, man has been trying to find an agent which would help burn wounds heal, and at the same time, not harm general condition of the injured. It was not until the XX century, after the discovery of antibiotics, when this condition was fulfilled. In 1968, combining silver and sulfadiazine, fox made silver-sulfadiazine, which is a 1% hydro-soluble cream and a superior agent in topical treatment of burns today. Current topical agents None of the topical antimicrobial agents available today, alone or combined, have the characteristics of ideal prophylactic agents, but they eliminate colonization of burn wound, and invasive infections are infrequent. With an excellent spectrum of activity, low toxicity, and ease of application with minimal pain, silver-sulfadiazine is still the most frequently used topical agent. Conclusion The incidence of invasive infections and overall mortality have been significantly reduced after introduction of topical burn wound antimicrobial agents into practice. In most burn patients the drug of choice for prophylaxis is silver sulfadiazine. Other agents may be useful in certain clinical situations.

  12. Pragmatic analysis of traditional Chinese short cartoons---Applying Qian Guanlian′s Pragmatic Theory to analyzing Jia′er Selling Apricots%中国传统动画短片的语用学分析--运用钱冠连“三带一理论”分析《贾二卖杏》

    Institute of Scientific and Technical Information of China (English)

    王钰; 刘金梅

    2013-01-01

    Animation production needs more creation of the story plot and language besides the technical support .Creativity and inspiration derive from the artists′experience in real life or what they have witnessed and heard in daily lives .The Chinese traditional short cartoon, with its unique design of the text creativity and story ideas , plays an important role in today′s anima-tion industry.This paper takes the text of the short cartoon “Jia′Er Sells Apricots” as the example of analysis, which is pro-duced by Nanjing Film Produce Plant in 1984.The authors have employed the pragmatic theory developed by Qian Guanlian to analyze the construction mode of the conversational texts and to elaborate their linguistic features so as to explore the pragmatic value of the traditional Chinese short cartoon′s conversational text.%  动画片的制作,除了需要技术支撑,更需要优秀的故事情节和文字创意。中国传统动画在文本创意和故事构想设计上具有其独到之处,并在今天的动画业界依然适用。本文以1984年由南京电影制片厂出品的动画短片《贾二卖杏》的文本为例,依据钱冠连的语用学“三带一理论”分析中国传统动画短片中会话语言的构建模式,并阐述其文本特点,旨在探索中国传统动画短片会话文本的语用价值。

  13. Selected topics of fluid mechanics

    Science.gov (United States)

    Kindsvater, Carl E.

    1958-01-01

    the Euler, Froude, Reynolds, Weber, and Cauchy numbers are defined as essential tools for interpreting and using experimental data. The derivations of the energy and momentum equations are treated in detail. One-dimensional equations for steady nonuniform flow are developed, and the restrictions applicable to the equations are emphasized. Conditions of uniform and gradually varied flow are discussed, and the origin of the Chezy equation is examined in relation to both the energy and the momentum equations. The inadequacy of all uniform-flow equations as a means of describing gradually varied flow is explained. Thus, one of the definitive problems of river hydraulics is analyzed in the light of present knowledge. This report is the outgrowth of a series of short schools conducted during the spring and summer of 1953 for engineers of the Surface Water Branch, Water Resources Division, U. S. Geological Survey. The topics considered are essentially the same as the topics selected for inclusion in the schools. However, in order that they might serve better as a guide and outline for informal study, the arrangement of the writer's original lecture notes has been considerably altered. The purpose of the report, like the purpose of the schools which inspired it, is to build a simple but strong framework of the fundamentals of fluid mechanics. It is believed that this framework is capable of supporting a detailed analysis of most of the practical problems met by the engineers of the Geological Survey. It is hoped that the least accomplishment of this work will be to inspire the reader with the confidence and desire to read more of the recent and current technical literature of modern fluid mechanics.

  14. Quantum mechanics II advanced topics

    CERN Document Server

    Rajasekar, S

    2015-01-01

    Quantum Mechanics II: Advanced Topics uses more than a decade of research and the authors’ own teaching experience to expound on some of the more advanced topics and current research in quantum mechanics. A follow-up to the authors introductory book Quantum Mechanics I: The Fundamentals, this book begins with a chapter on quantum field theory, and goes on to present basic principles, key features, and applications. It outlines recent quantum technologies and phenomena, and introduces growing topics of interest in quantum mechanics. The authors describe promising applications that include ghost imaging, detection of weak amplitude objects, entangled two-photon microscopy, detection of small displacements, lithography, metrology, and teleportation of optical images. They also present worked-out examples and provide numerous problems at the end of each chapter.

  15. Tracking Multiple Topics for Finding Interesting Articles

    Energy Technology Data Exchange (ETDEWEB)

    Pon, R K; Cardenas, A F; Buttler, D J; Critchlow, T J

    2007-02-15

    We introduce multiple topic tracking (MTT) for iScore to better recommend news articles for users with multiple interests and to address changes in user interests over time. As an extension of the basic Rocchio algorithm, traditional topic detection and tracking, and single-pass clustering, MTT maintains multiple interest profiles to identify interesting articles for a specific user given user-feedback. Focusing on only interesting topics enables iScore to discard useless profiles to address changes in user interests and to achieve a balance between resource consumption and classification accuracy. Also by relating a topic's interestingness to an article's interestingness, iScore is able to achieve higher quality results than traditional methods such as the Rocchio algorithm. We identify several operating parameters that work well for MTT. Using the same parameters, we show that MTT alone yields high quality results for recommending interesting articles from several corpora. The inclusion of MTT improves iScore's performance by 9% to 14% in recommending news articles from the Yahoo! News RSS feeds and the TREC11 adaptive filter article collection. And through a small user study, we show that iScore can still perform well when only provided with little user feedback.

  16. Visões de ciência em desenhos animados: uma alternativa para o debate sobre a construção do conhecimento científico em sala de aula Scientific views in cartoons: an alternative for debating about the construction of scientific knowledge in the classroom

    Directory of Open Access Journals (Sweden)

    Nyuara Araújo da Silva Mesquita

    2008-01-01

    Full Text Available Dada a grande influência da televisão na vida dos jovens, a presente pesquisa investigou um dos gêneros televisivos que se destina ao público infanto-juvenil: os desenhos animados. Esta investigação consiste em uma análise documental com base em alguns episódios dos desenhos Jimmy Nêutron e O Laboratório de Dexter, com a intenção de detectar quais visões de ciência são veiculadas por meio destes episódios. Tal análise realiza-se sob a ótica das idéias de alguns pensadores representativos da Filosofia das Ciências, por serem estas idéias importantes para a compreensão de como se desenvolveu e tem se desenvolvido o pensamento científico em nossa sociedade. O presente artigo sugere o uso de desenhos animados como alternativa para motivar debates que privilegiem a construção do conhecimento científico com base em um universo familiar ao estudante.Because of the big influence of TV in youngsters' lives, this research seeks to investigate one kind of TV program for children and teenagers. This investigation consists of a documentary analysis of some episodes of Jimmy Neutron and The Dexter Lab cartoons with the purpose of detecting which science views are broadcast in these episodes. The analysis is made from the point of view of some representative thinkers in the philosophy of science. These ideas are important in understanding how science thinking has developed in our society. This present article shows the use of cartoons as an alternative to motivate debates which will drive the construction of scientific knowledge using an environment familiar to the student.

  17. Selected topics in nuclear structure

    International Nuclear Information System (INIS)

    The Fourth International Conference on selected topics in nuclear structure was held at Dubna in July 1994 on recent experimental and theoretical investigations in nuclear structure. Topics discussed were the following: nuclear structure at low-energy excitations (collective quasiparticle phenomena, proton-neutron interactions, microscopic and phenomenological theories of nuclear structure; nuclear structure studies with charged particles. heavy ions, neutrons and photons; nuclei at high angular momenta and superdeformation, structure and decay properties of giant resonances, charge-exchange resonances and β-decay; semiclassical approach of large amplitude collective motion and structure of hot nuclei

  18. Orienting to Topic in Clinical Discourse Elicitation of Everyday Conversation

    Science.gov (United States)

    Fond, Marissa Joanne

    2013-01-01

    Talking topically, as it is understood intuitively and evoked metadiscursively, requires constructing an intersubjective orientation to talk that must be continually renewed. Analysis of interactants' ability to orient to topic emergence provides evidence of what is achieved in interaction, as well as why conversational coordination can lapse…

  19. The Impact of Topic Congruence on Second Language Reading Comprehension

    OpenAIRE

    Marzieh Sadeghpour; Sayyed Mohammad Alavi

    2013-01-01

    The present study scrutinized the impact of congruent topics on the quality of L2 reading comprehension. 56 Iranian advanced-level students read 2 texts on a controversial topic, one on the advantages of child gender selection, and the other on disadvantages. Quality analysis of immediate and delayed recall tasks, defined as the amount of high and low-level information recalled correctly, was performed by analysis of variance. Results revealed that topic congruence affected immediate recall o...

  20. Weakly-supervised joint sentiment-topic detection from text

    OpenAIRE

    Lin, Chenghua; He, Yulan; Everson, Richard; Rüger, Stefan

    2012-01-01

    Sentiment analysis or opinion mining aims to use automated tools to detect subjective information such as opinions, attitudes, and feelings expressed in text. This paper proposes a novel probabilistic modeling framework called joint sentiment-topic (JST) model based on latent Dirichlet allocation (LDA), which detects sentiment and topic simultaneously from text. A reparameterized version of the JST model called Reverse-JST, by reversing the sequence of sentiment and topic generation in the mo...

  1. 301 research topics from Skinner's book verbal behavior

    OpenAIRE

    Sundberg, Mark L.

    1991-01-01

    Skinner's (1957) analysis of verbal behavior addresses some of the most important issues in human behavior. However, relatively few of the analyses presented by Skinner in Verbal Behavior have been subjected to an experimental analysis. The current list of topics was assembled in an effort to stimulate empirical research on verbal behavior. The list contains thirty research areas with ten topics suggested for each area. A final topic, education, is presented as a challenge to behavior analysts.

  2. Rosacea-like eruption due to topical pimecrolimus.

    Science.gov (United States)

    El-Heis, S; Buckley, D A

    2015-05-01

    Topical calcineurin inhibitors have been used outside their approved indications for a number of conditions, including topical steroid-induced rosacea. However, tacrolimus ointment itself has been reported to trigger rosacea in a small number of cases. We report a case of a rosacea-like eruption in a 39-year-old woman occurring after the use of pimecrolimus cream for 12 months for atopic dermatitis. Withdrawal of pimecrolimus combined with treatment with oral lymecycline, topical metronidazole, and an emollient resulted in resolution of the eruption. There have been 5 previously reported cases of a topical pimecrolimus-induced rosacea-like eruption suggesting that this rare side-effect may be a class effect of all topical calcineurin inhibitors. Dermatologists prescribing these drugs should be aware of this uncommon complication and may wish to warn patients of its occurrence as a potential side-effect when using topical calcineurin inhibitors in facial skin in adults. PMID:26295863

  3. Rosacea-like eruption due to topical pimecrolimus.

    Science.gov (United States)

    El-Heis, S; Buckley, D A

    2015-05-18

    Topical calcineurin inhibitors have been used outside their approved indications for a number of conditions, including topical steroid-induced rosacea. However, tacrolimus ointment itself has been reported to trigger rosacea in a small number of cases. We report a case of a rosacea-like eruption in a 39-year-old woman occurring after the use of pimecrolimus cream for 12 months for atopic dermatitis. Withdrawal of pimecrolimus combined with treatment with oral lymecycline, topical metronidazole, and an emollient resulted in resolution of the eruption. There have been 5 previously reported cases of a topical pimecrolimus-induced rosacea-like eruption suggesting that this rare side-effect may be a class effect of all topical calcineurin inhibitors. Dermatologists prescribing these drugs should be aware of this uncommon complication and may wish to warn patients of its occurrence as a potential side-effect when using topical calcineurin inhibitors in facial skin in adults.

  4. Approach to extracting hot topics based on network traffic content

    Institute of Scientific and Technical Information of China (English)

    Yadong ZHOU; Xiaohong GUAN; Qindong SUN; Wei LI; Jing TAO

    2009-01-01

    This article presents the formal definition and description of popular topics on the Internet,analyzes the relationship between popular words and topics,and finally introduces a method that uses statistics and correlation of the popular words in traffic content and network flow characteristics as input for extracting popular topics on the Internet.Based on this,this article adapts a clustering algorithm to extract popular topics and gives formalized results.The test results show that this method has an accuracy of 16.7% in extracting popular topics on the Internet.Compared with web mining and topic detection and tracking (TDT),it can provide a more suitable data source for effective recovery of Internet public opinions.

  5. Sick sinus syndrome associated with topical timolol maleate instillation

    Directory of Open Access Journals (Sweden)

    Harpreet S Walia

    2011-01-01

    Full Text Available A 70-year-old black woman presented with intermittent palpitations and dyspnea was found to be bradycardic with a normal sinus rhythm. She had instilled her topical timolol maleate approximately 30 minutes prior to each of these episodes. Topical timolol was discontinued and the conduction abnormality resolved. She was diagnosed as having intermittent sinus bradycardia with intermittent atrioventricular block, likely induced by topical beta-blocker therapy. Topical timolol maleate is an effective treatment for ocular hypertension, acting by reducing aqueous fluid production. However, it can induce systemic side effects and should be used with caution in patients with, or predisposed to, cardiac or respiratory depression.

  6. Topics on cryogenic design of superconducting magnet for fusion reactor

    International Nuclear Information System (INIS)

    The design concepts and the research topics on cryogenic stability, quench and refrigeration of superconducting magnets for fusion experimental reactor are reviewed. Emphasis is given to introduce their fundamental ideas as well as the results obtained by various experiments at National Institute for Fusion Science, however, some of the other recent topics are also included. (author)

  7. Large scale topic modeling made practical

    DEFF Research Database (Denmark)

    Wahlgreen, Bjarne Ørum; Hansen, Lars Kai

    2011-01-01

    Topic models are of broad interest. They can be used for query expansion and result structuring in information retrieval and as an important component in services such as recommender systems and user adaptive advertising. In large scale applications both the size of the database (number of docume......Topic models are of broad interest. They can be used for query expansion and result structuring in information retrieval and as an important component in services such as recommender systems and user adaptive advertising. In large scale applications both the size of the database (number...... problem is reduced by use of large and carefully curated term set. We demonstrate the performance of the proposed system and in the process break a previously claimed ’world record’ announced April 2010 both by speed and size of problem. We show that the use of a WordNet derived vocabulary can identify...

  8. Investigation of some topical formulations containing dexpanthenol.

    Science.gov (United States)

    Stozkowska, Wiesława; Piekoś, Ryszard

    2004-01-01

    Owing to its ability to regenerate epidermal cells Dexpanthenol (D-panthenol; chemically known as (+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide) has found use for the treatment of patholytic ileus and postoperative distention. The purpose of research was to develop a gel containing dexpanthenol by monitoring the effect of various concentrations of a gelating agent on the activity of the ciliary apparatus. A system containing 2.5% of hydroxyethylcellulose was optimal for the preparation of the gel. Together with a formulation containing 5% of dexpanthenol, drops with equal concentration of the active compound were tested for comparison. Physical characteristics, such as osmotic pressure, acidity, density and viscosity of the preparation were determined as well as its microbiological sterility. The anti-inflammatory activity of the gel was determined following its topical application. Epidermal tests showed its good tolerance after topical application to the shaved skin of guinea pigs. PMID:15794335

  9. Topical and transdermal delivery of caffeine.

    OpenAIRE

    Luo, L.; Lane, M. E.

    2015-01-01

    Caffeine is administered topically and transdermally for a variety of pharmaceutical and cosmetic applications and it is also used as a model hydrophilic compound in dermal risk assessment studies. This review considers the physicochemical and permeation properties of caffeine with reference to its delivery to and through the skin. Since it has been used as a model compound the findings have implications for the delivery of many hydrophilic compounds having similar properties. Various passive...

  10. Supporting information visualization through topic maps

    OpenAIRE

    Marcos, Adérito; Oliveira, Alexandre Rocha; Malgueiro, Octávio; Grave, Luís

    2002-01-01

    We are living a phenomenon of accelerated information production with different accessing sources. Hence users are faced with a growing problem: accessing (navigation) and filtering specific information contained in large datasets, which are increasing in size. Procedures such as data filtering and gathering are now simplified through a new concept known as Topic Maps. The application of Virtual Reality technologies enables to present and interact with multidimensional information...

  11. Efficacy of topical calcineurin inhibitors in vitiligo.

    Science.gov (United States)

    Wong, Russell; Lin, Andrew N

    2013-04-01

    Topical tacrolimus and pimecrolimus are indicated for the treatment of atopic dermatitis, but they have been studied in many off-label uses. We reviewed the English language literature to define their roles in treatment of vitiligo. Double-blind studies show that tacrolimus 0.1% ointment combined with excimer laser is superior to placebo, especially for UV resistant areas, such as bony prominences of the extremities. When used alone, tacrolimus 0.1% ointment is almost as effective as clobetasol propionate 0.05% ointment. Other studies suggest it can also be effective for facial lesions. Double blind studies show that pimecrolimus 1% cream combined with narrow band UVB is superior to placebo, especially for facial lesions. Additional studies would further clarify the role of topical calcineurin inhibitors in vitiligo. PMID:23331250

  12. Topics from the theory of numbers

    CERN Document Server

    Grosswald, Emil

    1984-01-01

    Many of the important and creative developments in modern mathematics resulted from attempts to solve questions that originate in number theory. The publication of Emil Grosswald’s classic text presents an illuminating introduction to number theory. Combining the historical developments with the analytical approach, Topics from the Theory of Numbers offers the reader a diverse range of subjects to investigate, including: * divisibility * congruences * the Riemann zeta function * Diophantine equations and Fermat’s conjecture * the theory of partitions Comprehensive in nature, Topics from the Theory of Numbers is an ideal text for advanced undergraduates and graduate students alike. "In my opinion it is excellent. It is carefully written and represents clearly a work of a scholar who loves and understands his subject. One can only wish more authors would take such pains and would be as good and honest expositors as Grosswald." — Marc Kac "This book is designed for use in a first course in number theory at...

  13. Do scientists trace hot topics?

    CERN Document Server

    Wei, Tian; Wu, Chensheng; Yan, XiaoYong; Fan, Ying; Di, Zengru; Wu, Jinshan

    2013-01-01

    Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of papers belonging to the field. This indicates that scientists generally do follow hot topics. However, there are qualitative differences among scientists from various countries, among research works regarding different number of authors, different number of affiliations and different number of references. These observations could be valuable for policy makers when deciding research funding and also for individual researchers when searching for scientific projects.

  14. Efinaconazole topical solution, 10%: formulation development program of a new topical treatment of toenail onychomycosis.

    Science.gov (United States)

    Bhatt, V; Pillai, R

    2015-07-01

    Transungual drug delivery of antifungals is considered highly desirable to treat common nail disorders such as onychomycosis, due to localized effects, and improved adherence resulting from minimal systemic adverse events. However, the development of effective topical therapies has been hampered by poor nail penetration. An effective topical antifungal must permeate through, and under the dense keratinized nail plate to the site of infection in the nail bed and nail matrix. We present here the formulation development program to provide effective transungual and subungual delivery of efinaconazole, the first topical broad spectrum triazole specifically developed for onychomycosis treatment. We discuss the important aspects encompassing the formulation development program for efinaconazole topical solution, 10%, focusing on its solubility in a number of solvents, in vitro penetration through the nail, and in vivo efficacy. Efinaconazole topical solution, 10% is a stable, non-lacquer, antifungal with a unique combination of ingredients added to an alcohol-based formulation to provide low surface tension and good wetting properties. This low surface tension is believed to affect effective transungual delivery of efinaconazole and believed to provide a dual mode of delivery by accessing the nail bed by wicking into the space between the nail and nail plate.

  15. LEPA’S: TOPICAL APPLICATION OF AYURVEDA

    Directory of Open Access Journals (Sweden)

    Bali Yogitha

    2012-07-01

    Full Text Available The goal of medicine is to prevent the disease, restore health and suffering. Understanding and appropriately treating pain is an important component of this goal. Pain is universally recognized as a signal of disease or injury and is a common reason for patients to seek the medical care. Analgesics given in the form of topical application is said to provide the therapeutic benefits by reaching the local tissue and with minimal side effects like irritation of the skin etc. Apart form relieving the pain, topical application is also useful in treating various skin lesions, ulcers. Ayurveda, a science of life and traditional system of medicine native to India is also a form of Alternative medicine. Ayurveda also called as Astanga Ayurveda contains eight branches such as kayachikitsa(internal medicine, shalya tantra (surgery, shalakya tantra (ENT, agada tantra (toxicology and forensic medicine, bhutavidya (treatment of psychic diseases, kaumarabhrutya(paediatrics, rasayana tantra (rejuvenation treatment and vajikarana (aphrodiasics. Ayurveda, an ancient science has vast description of these topical applications in the name of lepa described both as the chikitsa of various disease conditions and for beauty.

  16. Preface to Special Topic: Optofluidics

    OpenAIRE

    Liu, Ai-qun

    2010-01-01

    This Special Topic section of Biomicrofluidics is on optofluidics or micro-optofluidic systems (MOFS), a burgeoning technology that aims to manipulate light and fluid at microscale and exploits their interaction to create highly versatile devices and integrated systems. This special issue puts together various contributed articles focusing on optofluidics or MOFS, which help inspire new research ideas and innovation in the microfluidics and nanofluidics community.

  17. Probabilistic analysis and related topics

    CERN Document Server

    Bharucha-Reid, A T

    1983-01-01

    Probabilistic Analysis and Related Topics, Volume 3 focuses on the continuity, integrability, and differentiability of random functions, including operator theory, measure theory, and functional and numerical analysis. The selection first offers information on the qualitative theory of stochastic systems and Langevin equations with multiplicative noise. Discussions focus on phase-space evolution via direct integration, phase-space evolution, linear and nonlinear systems, linearization, and generalizations. The text then ponders on the stability theory of stochastic difference systems and Marko

  18. Topics in clinical oncology. 15

    International Nuclear Information System (INIS)

    The monograph comprising primarily papers on topical subjects of oncology and cancer research, contains also a selection of papers presented at the 2. Congress of the Czechoslovak Society of Nuclear Medicine and Radiation Hygiene. Seven papers were selected on behalf of their subject related to clinical oncology. All of them were iputted in INIS; five of them deal with the scintiscanning of the skeleton of cancer patients, one with radioimmunodetection of tumors, and one with radionuclide lymphography. (A.K.)

  19. Hot topics from the Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Glenzinski, D.; /Fermilab

    2008-01-01

    The Tevatron Run-II began in March 2001. To date, both the CDF and D0 experiments have collected 1 fb{sup -1} of data each. The results obtained from this data set were summarized at this conference in 39 parallel session presentations covering a wide range of topics. The author summarizes the most important of those results here and comments on some of the prospects for the future.

  20. Immigration, Cultural-Linguistic Diversity, and Topics in Language Disorders

    Science.gov (United States)

    Cheng, Li-Rong Lilly

    2010-01-01

    This article summarizes 4 topics contributed by the author over the last 30 years of "Topics in Language Disorders" that address the issues of immigration, migration, and refugees. The focus is on the historical perspectives on evolution of terminologies from limited English proficient to English language learner and English as a new language.…

  1. Topical macrolide immunomodulators: a role in the treatment of vitiligo?

    NARCIS (Netherlands)

    Tjioe, M.; Vissers, W.H.P.M.; Gerritsen, M.J.P.

    2006-01-01

    Recently, topical macrolide immunomodulators have been successfully introduced in the treatment of atopic dermatitis. With the growing interest in this new line of topical immunosuppressants, research into the efficacy of these medicines in other T-cell-mediated skin diseases, such as psoriasis, lic

  2. Topics in Finance Part VII--Dividend Policy

    Science.gov (United States)

    Laux, Judy

    2011-01-01

    This series inspects the major topics in finance, reviewing the roles of stockholder wealth maximization, the risk-return tradeoff, and agency conflicts. The current article, devoted to dividend policy, also reviews the topic as presented in textbooks and the literature.

  3. Comparison of topical tretinoin and betamethasone in oral lichen planus

    Directory of Open Access Journals (Sweden)

    Kar H

    1996-01-01

    Full Text Available Thirty-one patients of oral lichen planus were enrolled in this study and two groups were made. Group 1 consisting of 16 patients who applied topical tretinoin 0.05% and Group 2 comprising of 15 patients who were given topical betamethasone dipropionate 0.05%. The patients applying tretinoin showed statistically significant improvement as compared to patients applying betamethasone.

  4. Topics in Finance Part VI--Capital Budgeting

    Science.gov (United States)

    Laux, Judy

    2011-01-01

    This series on the theory of financial management offers insight into the roles of stockholder wealth maximization, the risk-return tradeoff, and agency conflicts as they apply to major topics in finance. The current article investigates capital budgeting. Much literature addresses this topic, with a number of articles challenging mainstream…

  5. Modern topics in theoretical nuclear physics

    OpenAIRE

    Jennings, B. K.; Schwenk, A

    2005-01-01

    Over the past five years there have been profound advances in nuclear physics based on effective field theory and the renormalization group. In this brief, we summarize these advances and discuss how they impact our understanding of nuclear systems and experiments that seek to unravel their unknowns. We discuss future opportunities and focus on modern topics in low-energy nuclear physics, with special attention to the strong connections to many-body atomic and condensed matter physics, as wel...

  6. Topics in Cement and Concrete Research

    OpenAIRE

    Brouwers, H. J. H.

    2006-01-01

    The present paper addresses several topics in regard to the sustainable design and use of concrete. First, major features concerning the sustainable aspects of the material concrete are summarised. Then the major constituent, from an environmental point of view, cement is discussed in detail, particularly the hydration and application of slag cement. The intelligent combining of mineral oxides, which are found in clinker, slag, fly ashes etc., is designated as mineral oxide engineering. It re...

  7. LEPA’S: TOPICAL APPLICATION OF AYURVEDA

    OpenAIRE

    Bali Yogitha

    2012-01-01

    The goal of medicine is to prevent the disease, restore health and suffering. Understanding and appropriately treating pain is an important component of this goal. Pain is universally recognized as a signal of disease or injury and is a common reason for patients to seek the medical care. Analgesics given in the form of topical application is said to provide the therapeutic benefits by reaching the local tissue and with minimal side effects like irritation of the skin etc. Apart form relievin...

  8. LECITHINISED MICROEMULSIONS FOR TOPICAL DELIVERY OF TRETINOIN

    OpenAIRE

    Khanna Surabhi; Katare O P; Drabu Sushma

    2010-01-01

    Tretinoin is indicated for the management of acne, photoaged skin, psoriasis and other skin disorders and also for severe conditions like acute promyelocytic anaemia and squamous cell carcinoma of the skin. The potential of tretinoin in these conditions is limited due to want of a proper delivery vehicle. In order to develop alternate formulations for the topical administration of tretinoin, lecithinsed microemulsions were prepared and evaluated as delivery vehicles. These systems were prepar...

  9. Spontaneous Coronary Artery Dissection following Topical Hormone Replacement Therapy

    Directory of Open Access Journals (Sweden)

    Alexander L. Pan

    2012-01-01

    Full Text Available Spontaneous coronary artery dissection is a rare condition, usually presenting as an acute coronary syndrome, and is often seen in states associated with high systemic estrogen levels such as pregnancy or oral contraceptive use. While topical hormonal replacement therapy may result in increased estrogen levels similar to those documented with oral contraceptive use, there are no reported cases of spontaneous coronary dissection with topical hormonal replacement therapy. We describe a 53-year-old female who developed two spontaneous coronary dissections while on topical hormonal replacement therapy. The patient had no other risk factors for coronary dissection. After withdrawal from topical hormonal therapy, our patient has done well and has not had recurrent coronary artery dissections over a one-year follow-up period. The potential contributory role of topical hormonal therapy as a cause of spontaneous coronary dissection should be recognized.

  10. Self-realization-The Mechanism of Persuasion for the Spokesmen of Cartoon Images%自我实现--卡通形象代言人的劝服机制

    Institute of Scientific and Technical Information of China (English)

    于重榕

    2014-01-01

    与传统形象代言人相比,卡通形象代言人更适应消费者当下的思维观念。“自我实现”满足了消费者更高层次的心理需求,是卡通形象代言人实现劝服的内在原因,也是卡通形象代言人在产品营销策略中的核心依据。%Compared with the traditional spokesmen,the spokesmen of cartoon images are more suitable to the present thoughts and i-deas.Self-realization,meeting the physical needs for the consumers at the higher level,is the inner cause for the spokesmen of cartoon images to realization persuasion and is the core in the marketing strategies of the production.

  11. Topic-Focus Articulation of Isotopy

    Directory of Open Access Journals (Sweden)

    Radim Sova

    2012-09-01

    Full Text Available The paper deals with linguistic phenomena at suprasentential level. In particular, it looks into how textual analysis can be enhanced by supplementing the Parisian programme of interpretive semantics, as devised by François Rastier, namely his theory of isotopies, with elementary aspects of topic-focus articulation (TFA, as well as contextual boundness (CB and contextual non-boundness (CN, as elaborated within the Praguian linguistic tradition (V. Mathesius, P. Sgall, E. Hajičová, F. Daneš, J. Firbas, and how the descriptive power of the former can be increased by the latter. In this respect, it is argued that two types of TFA phenomena interact during any process of textual interpretation: those of topic-focus articulation at the level of sentence, conceiving lexical morphs as thematic (T and/or rhematic (R, as well as contextually bound (CB and/or contextually non-bound (CN, and those of topic-focus articulation at the level of isotopy, with each isotopy being conceived as structured around a center (an abstract semantic unit and periphery (a span of concrete utterances. Two types of such interaction are described, each defined by either correlation, or non-correlation of the CB and CN semes at the levels of isotopy and sentence, respectively: thematic-rhematic isotopy, induced by co-occurrence of the CB seme of the center and the CB seme of the periphery; and thematic-rhematic allotopy (i.e. non-isotopy, induced by co-occurrence of the CB seme of the center and the CN seme of the periphery. Since topic-focus isotopies and allotopies can be perceived as members of privative oppositions, a tentative system of such oppositions is presented, based on linguistic analyses of selected European Commission texts drafted in English and their Czech translations. The author’s ultimate intention is to show that the semantic features of topic-focus articulation at the sentential and suprasentential levels are both structurally parallel and

  12. Buying Blood Diamonds and Altering Global Capitalism. Mads Brügger as Unruly Artivist in The Ambassador

    DEFF Research Database (Denmark)

    Reestorff, Camilla Møhring

    2013-01-01

    because it rejects any explicit ethical claims and norms of participation, thus reproducing the self-same patterns of inequality that it seeks to document. This article studies the film as an unruly documentary that applies satire, cartoon aesthetics, and culture jamming as its artivist strategy...

  13. Application of Topic Map on Knowledge Organization

    Directory of Open Access Journals (Sweden)

    Sou-shan Wu

    2003-06-01

    Full Text Available Knowledge management (KM has received much attention from both academics and practitioners in the past few years. Following the KM trend, many organizations have built their own knowledge repositories or data warehouses. However, information or knowledge is still scattered everywhere without being properly managed. The rapid growth of the Internet accelerates the creation of unstructured and unclassified information and causes the explosion of information overload. The effort of browsing information through general-purpose search engines turns out to be tedious and painstaking. Hence, an effective technology to solve this information retrieval problem is much needed. The purpose of this research is to explore the application of text mining technique in organizing knowledge stored in unstructured natural language text documents. Major components of text mining techniques required for topic map in particular will be presented in detail.Two sets of unstructured documents are utilized to demonstrate the usage of SOM for topic categorization. The first set of documents is a collection of speeches given by Y.C. Wang, Chairman of the Taiwan Plastics Group, and the other is the collection of all laws and regulations related to securities and future markets in Taiwan. We also try to apply text mining to these two sets of documents to generate their respective topic maps, thus revealing the differences between organizing explicit and tacit knowledge as well as the difficulties associated with tacit knowledge.[Article content in Chinese

  14. Tracking Multiple Topics for Finding Interesting Articles

    Energy Technology Data Exchange (ETDEWEB)

    Pon, R K; Cardenas, A F; Buttler, D J; Critchlow, T J

    2008-01-03

    We introduce multiple topic tracking (MTT) for iScore to better recommend news articles for users with multiple interests and to address changes in user interests over time. As an extension of the basic Rocchio algorithm, traditional topic detection and tracking, and single-pass clustering, MTT maintains multiple interest profiles to identify interesting articles for a specific user given user-feedback. Focusing on only interesting topics enables iScore to discard useless profiles to address changes in user interests and to achieve a balance between resource consumption and classification accuracy. iScore is able to achieve higher quality results than traditional methods such as the Rocchio algorithm. We identify several operating parameters that work well for MTT. Using the same parameters, we show that MTT alone yields high quality results for recommending interesting articles from several corpora. The inclusion of MTT improves iScore's performance by 25% in recommending news articles from the Yahoo! News RSS feeds and the TREC11 adaptive filter article collection. And through a small user study, we show that iScore can still perform well when only provided with little user feedback.

  15. Nanociência e nanotecnologia como temáticas para discussão de ciência, tecnologia, sociedade e ambiente Nanoscience and Nanotechnology as topical themes for a discussion on science, technology, society and environment

    Directory of Open Access Journals (Sweden)

    Rodrigo Siqueira-Batista

    2010-01-01

    Full Text Available A educação científica e tecnológica tem sido intensamente discutida hodiernamente, tendo em vista o compromisso último das diferentes instituições de ensino: formar cidadãos capazes de entender o mundo no qual estão inseridos. Com efeito, a apreciação de temas da atualidade se constitui em abordagem bastante salutar para motivar as discussões sobre tais temáticas em sala de aula. Neste domínio se inserem a nanociência e a nanotecnologia, saberes que podem ser abordados de forma interdisciplinar, envolvendo as ciências exatas e da natureza de forma articulada às ciências humanas e sociais. A proposição de eixos temáticos para o emprego da nanociência e da nanotecnologia como mote para o ensino de ciências, construídos a partir da revisão da literatura sob um enfoque ciência-tecnologia-sociedade-ambiente (CTSA é o escopo do presente artigo.Scientific and technological education has been, in present times, fairly-well discussed, with focus on the ultimate commitment of the various teaching institutions: to promote the formation of citizens who are able to understand the world where they live in. Actually, the choice of contemporary topics is by itself a very strategic approach to motivate discussions on such matters in the classroom. Nanoscience and nanotechnology come up very properly in such a domain, which can be treated in an interdisciplinary way, by joining exact and natural sciences on the one hand, and human and social sciences on the other hand. The proposal of thematic directions to approach nanoscience and nanotechnology as a motto for science teaching, set up from reviewing the literature under the optics of Science-Technology-Society-Environment (STSE, is the main goal of the present paper.

  16. Microblog Hot Spot Mining Based on PAM Probabilistic Topic Model

    Directory of Open Access Journals (Sweden)

    Zheng Yaxin

    2015-01-01

    Full Text Available Microblogs are short texts carried with limited information, which will increase the difficulty of topic mining. This paper proposes the use of PAM (Pachinko Allocation Model probabilistic topic model to extract the generative model of text’s implicit theme for microblog hot spot mining. First, three categories of microblog and the main contribution of this paper are illustrated. Second, for there are four topic models which are respectively explained, the PAM model is introduced in detail in terms of how to generate a document, the accuracy of document classification and the topic correlation in PAM. Finally, MapReduce is described. For the number of microblogs is huge as well as the number of contactors, the totally number of words is relatively small. With MapReduce, microblogs data are split by contactor, document-topic count matrix and contactor-topic count matrix can be locally stored while the word-topic count matrix must be globally stored. Thus, the hot spot mining can be achieved on the basis of PAM probabilistic topic model.

  17. Attitude, Forms and Methods ——Lu Xun's Cartoon Creation Thoughts%态度、形式与方法——鲁迅的漫画创作思想

    Institute of Scientific and Technical Information of China (English)

    杨向荣; 赵玉彩

    2015-01-01

    From the "real" and "true" forms of writing attitude to the creation of the"clear", and to the creation of the "exaggeration"and "expand" methods of comic, Lu Xun put forward a series of deep and highly theoretical comics thoughts. The cartoon creation thoughts of Lu Xun is the core of Lu Xun's aesthetic thoughts, and is a try and save strategies to social reality of China. Lu Xun's cartoon creation thoughts fill the gaps in early comic theory, and are an antidote for lack of the spirit of today's cartoon creation.%从漫画"真实"与"真情"的创作态度到"一目了然"的创作形式,再到"夸张"与"廓大"的创作方法,鲁迅提出了一系列深刻且极具理论性的漫画思想.鲁迅的漫画创作思想是鲁迅美学思想的核心,也是鲁迅面对中国的社会现实而采取的一种艺术尝试和拯救策略.鲁迅的漫画创作思想填补了我们早期漫画理论的空白,并为当下漫画创作的精神缺失留下了一剂良方.

  18. 虚拟现实技术发展启发新媒体动画创作方式的新思路%A New Perspective of Virtual Reality Technology Enlightenment on New Medium Cartoon Creation

    Institute of Scientific and Technical Information of China (English)

    刘庆科

    2014-01-01

    Along with the rapid development in digital technology, animation technology is constantly changing, so the method of producing cartoon is profoundly shocked by new technologies. The revolution and advancement caused by digitization has surpassed those of any other time in history. Nowadays, every special jargon resounds in our ears and every technical patent is introduced into the ifeld of cartoon creation. The essay combines virtual reality with animation to ilustrate development orientation and future of new medium cartoon.%随着数字技术迅速发展,动画技术也是日新月异,动画的创作方式更是受到新技术强大的冲击。数字化给动画的创作方式所带来的变革,已经远远的超越了以往任何一个时代的技术给动画创作方式所带来的进步。如今一个个新的专业术语回响在我们的耳边,一项项的技术专利引入到动画创作领域。本文将虚拟现实和动画相结合试图阐释新媒体动画的发展方向和未来。

  19. Topics on Electricity Transmission Pricing

    International Nuclear Information System (INIS)

    -subsidization, the largest state-owned firm was split to form Statkraft SF, Norway's largest generation company, and Statnett SF, the major transmission company. Statnett is also the system operator of the entire Norwegian power system. Many distribution companies, usually publicly owned, are still part of vertically integrated companies, but there is strict separation of the financial accounts for transmission/distribution and generation/marketing. Trading is accomplished through several channels. The largest organized market is the common Norwegian-Swedish pool, NordPool. NordPool ASA is owned by Statnett Marked (which is a subsidiary of Statnett) and the Swedish grid-company, Svenska Kraftnaet. NordPool also supports the Finnish and Danish markets, thus through cooperation with the grid-companies of Denmark (Eltra) and Finland (Fingrid), locational markets are provided in these countries as well. Unlike England and Wales, only part of actual production is traded on this market. In addition, independent brokers offer various energy-contracts and facilitate bilateral contracts. In 1998 22% of the energy was traded on the hourly day-ahead (spot) market of NordPool. NordPool also organizes a forward and futures market and settles contracts from the regulation market organized by Statnett. The regulation market is a realtime market used to settle imbalances in real time. In total, close to 30% of the energy traded is organized through NordPool, and this share is increasing year by year. The efficiency of the market is heavily affected by the operation and pricing of the transmission system, and the topic of this thesis concerns the interaction of the transmission network and the energy markets. Throughout, the findings are illustrated by means of simple examples. This is to enhance readability and intuition. To start with, chapter 2 is devoted to power flow models, whereas chapter 3 provides an overview of models developed to efficiently coordinate the allocation of transmission

  20. 实时三维人体卡通运动的设计与实现%Real-Time 3D Human Cartoon Animation System

    Institute of Scientific and Technical Information of China (English)

    刘登志; 卢书芳; 万贤美; 金小刚

    2011-01-01

    This paper presents a novel method for generating 3D real-time cartoon animation. We first use the Laplacian of Gaussian (LoG) filter to process the motion capture data, which results in a more “alive” or “animated” animation style. Then, we use the analogy to heat equilibrium to automatically rig the mesh model. After that, we retarget the filtered data to the rigged mesh model and generate cartoon animation sequences. The spherical blend skinning (SBS) is employed to avoid collapse and candy wrapper artifacts, which costs low computation and memory space. The advantage of the presented method lies in its simplicity and real-time performance. Experiments show that our approach can produce satisfactory results. The system is easy to use even for novices.%为了实现虚拟角色的三维卡通运动,提出一种结合卡通滤波与骨骼模型自动绑定的实时生成算法.首先运用高斯拉普拉斯算子对捕获的运动数据进行滤波,然后用热量平衡的原理来自动绑定给定的人体模型,最后将滤波后的运动数据加载到绑定好的模型中,生成卡通化的夸张的动画序列.为了避免出现"collapse"和"candy wrapper"等走样现象,采用了SBS算法对网格进行变形.运动捕获数据滤波与蒙皮过程均使用GPU进行了加速.实验结果表明,运用该算法生成的动画效果满足动画法则,网格变形后表面光滑,用户交互简单.