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Sample records for care nap sacc

  1. NAP SACC: Implementation of an Obesity Prevention Intervention in an American Indian Head Start Program.

    Science.gov (United States)

    Mattingly, Julie A; Andresen, Pamela A

    2016-01-01

    Low-income American Indian preschoolers are at greatest risk for overweight and obesity among children aged 2-5 years. The Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) program is an evidence-based intervention that promotes healthy weight development for children enrolled in child care centers. The goal of this continuous quality improvement program is for the child care staff to establish environmental policies and practices that positively influence nutrition and physical activity-related behaviors. A community needs assessment of a Head Start program on an American Indian reservation identified obesity as a priority issue. This project implemented NAP SACC at 15 Head Start sites on the reservation. PMID:27383778

  2. Nutrition and physical activity randomized control trial in child care centers improves knowledge, policies, and children's body mass index.

    OpenAIRE

    Alkon, A; Crowley, AA; Neelon, SE; Hill, S.; Pan, Y.; Nguyen, V.; Rose, R.; Savage, E; Forestieri, N; Shipman, L; Kotch, JB

    2014-01-01

    BACKGROUND: To address the public health crisis of overweight and obese preschool-age children, the Nutrition And Physical Activity Self Assessment for Child Care (NAP SACC) intervention was delivered by nurse child care health consultants with the objective of improving child care provider and parent nutrition and physical activity knowledge, center-level nutrition and physical activity policies and practices, and children's body mass index (BMI). METHODS: A seven-month randomized control tr...

  3. ANP3 & NAP2

    DEFF Research Database (Denmark)

    Lindberg, Erik

    1996-01-01

    Modelling and SimulationANP3 introductionNAP2 introductionThe Exended Node EquationsThe input languages of ANP3 and NAP2The output from ANP3 and NAP2Literature......Modelling and SimulationANP3 introductionNAP2 introductionThe Exended Node EquationsThe input languages of ANP3 and NAP2The output from ANP3 and NAP2Literature...

  4. Advanced Stellar Compass, SAC-C, Interface Control Document

    DEFF Research Database (Denmark)

    Madsen, Peter Buch; Betto, Maurizio; Riis, Troels;

    Interface Control Document for the Advanced Stellar Compass for the SAC-C satellite. The SAC-C is Argentine, Danish and NASA satellite. On the SAC-C satellite there are a simplified version of the Ørsted instrumentation platform. The Advanced Stellar Compass is a improved version of the Ørsted Star...... Imager. This document descibes the interface between the Advanced Stellar Compass and OBDH, the size of the DPU and the Camera etc....

  5. Unit 6 Nap Time

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正> Story: After a busy morning,it is time for a little rest."It’s nap time. Take off your shoes,"says Miss Grant. She helps everyone get their sleeping bags and makes sure that everyone has put their shoes outside Before everyone falls asleep they ask the teacher," Read us a story, please."

  6. Documentation for delivery of Star Tracker to SAC-C

    DEFF Research Database (Denmark)

    Kilsgaard, Søren; Thuesen, Gøsta; Riis, Troels;

    1999-01-01

    The documentation EIDP (End Item Data Package) describes all the tests which have been performed on the flight hardware of the Star Tracker for the Argentine, Danish and NASA satellite SAC-C.......The documentation EIDP (End Item Data Package) describes all the tests which have been performed on the flight hardware of the Star Tracker for the Argentine, Danish and NASA satellite SAC-C....

  7. Alertness management in flight operations - Strategic napping

    Science.gov (United States)

    Rosekind, Mark R.; Gander, Philippa H.; Dinges, David F.

    1991-01-01

    Strategic napping in two different flight operation environments is considered to illustrate its application as a fatigue countermeasure. Data obtained from commercial short-haul and long-haul operations demonstrated the utility and current practices of strategic napping. A preplanned cockpit nap acted as an acute 'safety valve' for the sleep loss, circadian disruption, and fatigue that occurs in long-haul flying.

  8. Daytime nap controls toddlers’ nighttime sleep

    Science.gov (United States)

    Nakagawa, Machiko; Ohta, Hidenobu; Nagaoki, Yuko; Shimabukuro, Rinshu; Asaka, Yoko; Takahashi, Noriko; Nakazawa, Takayo; Kaneshi, Yousuke; Morioka, Keita; Oishi, Yoshihisa; Azami, Yuriko; Ikeuchi, Mari; Takahashi, Mari; Hirata, Michio; Ozawa, Miwa; Cho, Kazutoshi; Kusakawa, Isao; Yoda, Hitoshi

    2016-01-01

    Previous studies have demonstrated that afternoon naps can have a negative effect on subsequent nighttime sleep in children. These studies have mainly been based on sleep questionnaires completed by parents. To investigate the effect of napping on such aspects of sleep quality, we performed a study in which child activity and sleep levels were recorded using actigraphy. The parents were asked to attach actigraphy units to their child’s waist by an adjustable elastic belt and complete a sleep diary for 7 consecutive days. 50 healthy young toddlers of approximately 1.5 years of age were recruited. There was a significant negative correlation between nap duration and both nighttime sleep duration and sleep onset time, suggesting that long nap sleep induces short nighttime sleep duration and late sleep onset time. We also found a significant negative correlation between nap timing and nighttime sleep duration and also a significant positive correlation between nap timing and sleep onset time, suggesting that naps in the late afternoon also lead to short nighttime sleep duration and late sleep onset. Our findings suggest that duration-controlled naps starting early in the afternoon can induce a longer nighttime sleep in full-term infants of approximately 1.5 years of age. PMID:27277329

  9. Daydreams and nap dreams: Content comparisons.

    Science.gov (United States)

    Carr, Michelle; Nielsen, Tore

    2015-11-01

    Differences between nighttime REM and NREM dreams are well-established but only rarely are daytime REM and NREM nap dreams compared with each other or with daydreams. Fifty-one participants took daytime naps (with REM or NREM awakenings) and provided both waking daydream and nap dream reports. They also provided ratings of their bizarreness, sensory experience, and emotion intensity. Recall rates for REM (96%) and NREM (89%) naps were elevated compared to typical recall rates for nighttime dreams (80% and 43% respectively), suggesting an enhanced circadian influence. All attribute ratings were higher for REM than for NREM dreams, replicating findings for nighttime dreams. Compared with daydreams, NREM dreams had lower ratings for emotional intensity and sensory experience while REM dreams had higher ratings for bizarreness and sensory experience. Results support using daytime naps in dream research and suggest that there occurs selective enhancement and inhibition of specific dream attributes by REM, NREM and waking state mechanisms.

  10. Antimicrobial activity from endophytic fungi Arthrinium state of Apiospora montagnei Sacc. and Papulaspora immersa

    OpenAIRE

    Henrique Pereira Ramos; Glaucia Hollander Braun; Mônica Tallarico Pupo; Suraia Said

    2010-01-01

    Papulaspora immersa and Arthrinium state of Apiospora montagnei Sacc. were isolated from the roots of Smallanthus sonchifolius (yacón). The crude extracts from their cultures inhibited the growth of Staphylococcus aureus, Kocuria rhizophila, Pseudomonas aeruginosa and Escherichia coli. The more relevant results were observed in the ethyl acetate extract from P immersa against P aeruginosa (90 µg/mL) and ethyl acetate extract from Arthrinium state of A montagnei Sacc. against P aeruginosa (160...

  11. Risperidone and NAP protect cognition and normalize gene expression in a schizophrenia mouse model.

    Science.gov (United States)

    Vaisburd, Sinaya; Shemer, Zeev; Yeheskel, Adva; Giladi, Eliezer; Gozes, Illana

    2015-11-10

    Mutated disrupted in schizophrenia 1 (DISC1), a microtubule regulating protein, leads to schizophrenia and other psychiatric illnesses. It is hypothesized that microtubule stabilization may provide neuroprotection in schizophrenia. The NAP (NAPVSIPQ) sequence of activity-dependent neuroprotective protein (ADNP) contains the SxIP motif, microtubule end binding (EB) protein target, which is critical for microtubule dynamics leading to synaptic plasticity and neuroprotection. Bioinformatics prediction for FDA approved drugs mimicking SxIP-like motif which displace NAP-EB binding identified Risperidone. Risperidone or NAP effectively ameliorated object recognition deficits in the mutated DISC1 mouse model. NAP but not Risperidone, reduced anxiety in the mutated mice. Doxycycline, which blocked the expression of the mutated DISC1, did not reverse the phenotype. Transcripts of Forkhead-BOX P2 (Foxp2), a gene regulating DISC1 and associated with human ability to acquire a spoken language, were increased in the hippocampus of the DISC1 mutated mice and were significantly lowered after treatment with NAP, Risperidone, or the combination of both. Thus, the combination of NAP and standard of care Risperidone in humans may protect against language disturbances associated with negative and cognitive impairments in schizophrenia.

  12. The association between daytime napping and cognitive functioning in chronic fatigue syndrome.

    Directory of Open Access Journals (Sweden)

    Zoe M Gotts

    Full Text Available The precise relationship between sleep and physical and mental functioning in chronic fatigue syndrome (CFS has not been examined directly, nor has the impact of daytime napping. This study aimed to examine self-reported sleep in patients with CFS and explore whether sleep quality and daytime napping, specific patient characteristics (gender, illness length and levels of anxiety and depression, predicted daytime fatigue severity, levels of daytime sleepiness and cognitive functioning, all key dimensions of the illness experience.118 adults meeting the 1994 CDC case criteria for CFS completed a standardised sleep diary over 14 days. Momentary functional assessments of fatigue, sleepiness, cognition and mood were completed by patients as part of usual care. Levels of daytime functioning and disability were quantified using symptom assessment tools, measuring fatigue (Chalder Fatigue Scale, sleepiness (Epworth Sleepiness Scale, cognitive functioning (Trail Making Test, Cognitive Failures Questionnaire, and mood (Hospital Anxiety and Depression Scale.Hierarchical Regressions demonstrated that a shorter time since diagnosis, higher depression and longer wake time after sleep onset predicted 23.4% of the variance in fatigue severity (p <.001. Being male, higher depression and more afternoon naps predicted 25.6% of the variance in objective cognitive dysfunction (p <.001. Higher anxiety and depression and morning napping predicted 32.2% of the variance in subjective cognitive dysfunction (p <.001. When patients were classified into groups of mild and moderate sleepiness, those with longer daytime naps, those who mainly napped in the afternoon, and those with higher levels of anxiety, were more likely to be in the moderately sleepy group.Napping, particularly in the afternoon is associated with poorer cognitive functioning and more daytime sleepiness in CFS. These findings have clinical implications for symptom management strategies.

  13. NAPS: Network Analysis of Protein Structures.

    Science.gov (United States)

    Chakrabarty, Broto; Parekh, Nita

    2016-07-01

    Traditionally, protein structures have been analysed by the secondary structure architecture and fold arrangement. An alternative approach that has shown promise is modelling proteins as a network of non-covalent interactions between amino acid residues. The network representation of proteins provide a systems approach to topological analysis of complex three-dimensional structures irrespective of secondary structure and fold type and provide insights into structure-function relationship. We have developed a web server for network based analysis of protein structures, NAPS, that facilitates quantitative and qualitative (visual) analysis of residue-residue interactions in: single chains, protein complex, modelled protein structures and trajectories (e.g. from molecular dynamics simulations). The user can specify atom type for network construction, distance range (in Å) and minimal amino acid separation along the sequence. NAPS provides users selection of node(s) and its neighbourhood based on centrality measures, physicochemical properties of amino acids or cluster of well-connected residues (k-cliques) for further analysis. Visual analysis of interacting domains and protein chains, and shortest path lengths between pair of residues are additional features that aid in functional analysis. NAPS support various analyses and visualization views for identifying functional residues, provide insight into mechanisms of protein folding, domain-domain and protein-protein interactions for understanding communication within and between proteins. URL:http://bioinf.iiit.ac.in/NAPS/. PMID:27151201

  14. Cordyceamides A and B from the Culture Liquid of Cordyceps sinensis (BERK.) SACC.

    Science.gov (United States)

    Jia, Jing-Ming; Tao, Hai-Hua; Feng, Bao-Min

    2009-01-01

    Two new aurantiamides named as cordyceamides A and B were isolated from the culture liquid of Cordyceps sinensis (BERK.) SACC., along with one known compound, aurantiamide acetate. Their structures were elucidated as N-benzoyl-L-tyrosinyl-L-phenylalaninol acetate and N-benzoyl-L-tyrosinyl-L-p-hydroxyphenylalaninol acetate by 1D, 2D-NMR techniques and comparison with literatures. PMID:19122327

  15. Subjective and Objective Napping and Sleep in Older Adults: Are Evening Naps ‘Bad’ for Nighttime Sleep?

    Science.gov (United States)

    Dautovich, Natalie D.; McCrae, Christina S.; Rowe, Meredeth

    2014-01-01

    Objectives To compare objective and subjective measurements of napping, and to examine the relationship between evening napping and nocturnal sleep in older adults. Design For twelve days, participants wore actigraphs and completed sleep diaries. Setting Community Participants 100 individuals who napped, 60–89 years (including good and poor sleepers with typical age-related medical comorbidities). Measurements Twelve days of sleep diary and actigraphy provided subjective and objective napping and sleep data. Results Evening naps (within 2 hours of bedtime) were characteristic of the sample with peak nap time occurring between 20:30–21:00 (average nap time occurred between 14:30–15:00). Two categories of nappers were identified: 1) day/evening – those who took both daytime and evening naps, and 2) daytime-only. Interestingly, no participants napped during the evening only. Day/evening nappers significantly underreported evening napping and demonstrated lower objectively measured sleep onset latencies (20 vs 26.5 minutes), less wake after sleep onset (51.4 vs 72.8 minutes), and higher sleep efficiencies (76.8 vs 82%) than daytime-only nappers. Conclusion Day/evening napping was prevalent amongst this sample of community-dwelling good/poor sleepers, but was not associated with impaired nocturnal sleep. Although the elimination or restriction of napping is a common element of cognitive-behavioral therapy for insomnia (CBTi), these results suggest that a uniform recommendation to restrict/eliminate napping (particularly evening napping) may not meet the needs of all older individuals with insomnia. PMID:18691289

  16. MECHANISM OF FUSARIUM TRICINCTUM (CORDA) SACC. SPORE INACTIVATION BY CHLORINE DIOXIDE

    OpenAIRE

    Zhao Chen

    2015-01-01

    The mechanism of Fusarium tricinctum (Corda) Sacc. spore inactivation by chlorine dioxide (ClO2) was investigated. During F. tricinctum spore inactivation by ClO2, protein, DNA, and metal ion leakage, enzyme activity, and cell ultrastructure were examined. Protein and DNA leakages were not detected, while there were metal ion leakages of K+, Ca2+, and Mg2+, which were well-correlated with the inactivation rate. The enzyme activities of glucose-6-phosphate dehydrogenase, citrate synthase, and ...

  17. A new variety of Pholiota microspora (Berk. Sacc. (Agaricales from Nepal

    Directory of Open Access Journals (Sweden)

    MAHESH K. ADHIKARI

    2014-10-01

    Full Text Available In the fall of late rainy season 2011, a new Pholiota (Fr. P. Kumm. (Agaricales, Strophariaceae was collected in the Quercus forest of Phulchowki (Kathmandu valley along the trial line, on the dead log at an altitude of 2600m. The specimen gathered was quite small. It was brought to laboratory and cultivated in NARC, Pathology laboratory, Lalitpur. The mushroom has been identified as Pholiota microspora (Berk. Sacc. var. himalensis var. nov..

  18. Promoting alertness with a short nap during a night shift.

    Science.gov (United States)

    Sallinen, M; Härmä, M; Akerstedt, T; Rosa, R; Lillqvist, O

    1998-12-01

    The use of a short (nap in improving alertness during the early morning hours in the first night shift was examined under laboratory conditions. The study contained four experimental, non-consecutive night shifts with a nap of either 50 or 30 min at 01.00 or 04.00 hours. An experimental night shift without a nap served as a control condition. Each experimental shift was followed by daytime sleep. Fourteen experienced male shift workers went through all of the experimental conditions. The results showed that the naps improved the ability to respond to visual signals during the second half of the night shift. Physiological sleepiness was alleviated by the early naps, as measured 50 min after awakening, but not at the end of the shift. Subjective sleepiness was somewhat decreased by the naps. The naps produced sleep inertia which lasted for about 10-15 min. Daytime sleep was somewhat impaired by the 50 min naps. The study shows that a nap shorter than 1 h is able to improve alertness to a certain extent during the first night shift.

  19. Evaluation of Refractivity Profiles from CHAMP and SAC-C GPS Radio Occultation

    Science.gov (United States)

    Poli, Paul; Ao, Chi On; Joiner, Joanna; delaTorreJuarez, Manuel; Hoff, Raymond

    2002-01-01

    The GeoForschungsZentrum's Challenging Minisatellite Payload for Geophysical Research and Application (CHAMP, Germany-US) and the Comision Nacional de Actividades Especiales' Satelite de Aplicaciones Cientificas-C (SAC-C, Argentina-US) missions are the first missions to carry a second-generation Blackjack Global Positioning System (GPS) receiver. One of the new features of this receiver is its ability to sense the lower troposphere closer to the surface than the proof-of-concept GPS Meteorology experiment (GPS/MET). Since their launch, CHAMP and SAC-C have collected thousands of GPS radio occultations, representing a wealth of measurements available for data assimilation and Numerical Weather Prediction (NWP). In order to evaluate the refractivity data derived by the Jet Propulsion Laboratory (JPL) from raw radio occultation measurements, we use Data Assimilation Office (DAO) 6-hour forecasts as an independent state of the atmosphere. We compare CHAMP and SAC-C refractivity (processed by JPL) with refractivity calculated from the DAO global fields of temperature, water vapor content and humidity. We show statistics of the differences as well as histograms of the differences.

  20. Effects of the length and timing of nighttime naps on task performance and physiological function

    Directory of Open Access Journals (Sweden)

    Hidemaro Takeyama

    2004-12-01

    Full Text Available OBJECTIVE: To examine the effects of the length and timing of nighttime naps on performance and physiological functions, an experimental study was carried out under simulated night shift schedules. METHODS: Six students were recruited for this study that was composed of 5 experiments. Each experiment involved 3 consecutive days with one night shift (22:00-8:00 followed by daytime sleep and night sleep. The experiments had 5 conditions in which the length and timing of naps were manipulated: 0:00-1:00 (E60, 0:00-2:00 (E120, 4:00-5:00 (L60, 4:00-6:00 (L120, and no nap (No-nap. During the night shifts, participants underwent performance tests. A questionnaire on subjective fatigue and a critical flicker fusion frequency test were administered after the performance tests. Heart rate variability and rectal temperature were recorded continuously during the experiments. Polysomnography was also recorded during the nap. RESULTS: Sleep latency was shorter and sleep efficiency was higher in the nap in L60 and L120 than that in E60 and E120. Slow wave sleep in the naps in E120 and L120 was longer than that in E60 and L60. The mean reaction time in L60 became longer after the nap, and faster in E60 and E120. Earlier naps serve to counteract the decrement in performance and physiological functions during night shifts. Performance was somewhat improved by taking a 2-hour nap later in the shift, but deteriorated after a one-hour nap. CONCLUSIONS: Naps in the latter half of the night shift were superior to earlier naps in terms of sleep quality. However performance declined after a 1-hour nap taken later in the night shift due to sleep inertia. This study suggests that appropriate timing of a short nap must be carefully considered, such as a 60-min nap during the night shift.OBJETIVO: Para investigar os efeitos da duração e horário de cochilos noturnos sobre o desempenho e as funções fisiológicas foi realizado um estudo experimental por meio do trabalho

  1. Daytime napping associated with increased symptom severity in fibromyalgia syndrome

    NARCIS (Netherlands)

    Theadom, Alice; Cropley, Mark; Kantermann, Thomas

    2015-01-01

    Background: Previous qualitative research has revealed that people with fibromyalgia use daytime napping as a coping strategy for managing symptoms against clinical advice. Yet there is no evidence to suggest whether daytime napping is beneficial or detrimental for people with fibromyalgia. The purp

  2. Napping facilitates word learning in early lexical development.

    Science.gov (United States)

    Horváth, Klára; Myers, Kyle; Foster, Russell; Plunkett, Kim

    2015-10-01

    Little is known about the role that night-time sleep and daytime naps play in early cognitive development. Our aim was to investigate how napping affects word learning in 16-month-olds. Thirty-four typically developing infants were assigned randomly to nap and wake groups. After teaching two novel object-word pairs to infants, we tested their initial performance with an intermodal preferential looking task in which infants are expected to increase their target looking time compared to a distracter after hearing its auditory label. A second test session followed after approximately a 2-h delay. The delay contained sleep for the nap group or no sleep for the wake group. Looking behaviour was measured with an automatic eye-tracker. Vocabulary size was assessed using the Oxford Communicative Development Inventory. A significant interaction between group and session was found in preferential looking towards the target picture. The performance of the nap group increased after the nap, whereas that of the wake group did not change. The gain in performance correlated positively with the expressive vocabulary size in the nap group. These results indicate that daytime napping helps consolidate word learning in infancy. PMID:25950233

  3. The use of caffeine versus prophylactic naps in sustained performance.

    Science.gov (United States)

    Bonnet, M H; Gomez, S; Wirth, O; Arand, D L

    1995-02-01

    Previous studies have shown that performance during sleep loss is improved by prophylactic naps as a function of varying nap length. Based on single-dose caffeine studies, a similar dose-response effect has been hypothesized on performance, alertness and mood during sleep loss. The present study compared the effects of repeated versus single-dose administration of caffeine and varying amounts of sleep taken prior to sleep loss on performance, mood and physiological measures during 2 nights and days of sleep loss. A total of 140 normal, young adult males participated at one of two study sites. Ninety-eight subjects at one site were randomly assigned to one of four nap conditions (0, 2, 4 or 8 hours) and 42 subjects at the second site were assigned to one of four caffeine conditions. After a normal baseline night of sleep and morning baseline tests of performance, mood and nap latency, subjects in the nap groups returned to bed at noon, 1600 hours, 1800 hours or not at all. Bedtimes were varied so that all naps ended at 2000 hours. Subjects in the caffeine groups received either a single 400-mg dose of caffeine at 0130 hours each night or repeated doses of 150 or 300 mg every 6 hours starting at 0130 hours on the 1st night of sleep loss. A placebo control group (no nap and placebo administered every 6 hours on the repeated caffeine schedule) was run at both sites.(ABSTRACT TRUNCATED AT 250 WORDS)

  4. Electron transport to periplasmic nitrate reductase (NapA) of Wolinella succinogenes is independent of a NapC protein.

    Science.gov (United States)

    Simon, Jörg; Sänger, Monica; Schuster, Stephan C; Gross, Roland

    2003-07-01

    The rumen bacterium Wolinella succinogenes grows by respiratory nitrate ammonification with formate as electron donor. Whereas the enzymology and coupling mechanism of nitrite respiration is well known, nitrate reduction to nitrite has not yet been examined. We report here that intact cells and cell fractions catalyse nitrate and chlorate reduction by reduced viologen dyes with high specific activities. A gene cluster encoding components of a putative periplasmic nitrate reductase system (napA, G, H, B, F, L, D) was sequenced. The napA gene was inactivated by inserting a kanamycin resistance gene cassette. The resulting mutant did not grow by nitrate respiration and did not reduce nitrate during growth by fumarate respiration, in contrast to the wild type. An antigen was detected in wild-type cells using an antiserum raised against the periplasmic nitrate reductase (NapA) from Paracoccus pantotrophus. This antigen was absent in the W. succinogenes napA mutant. It is concluded that the periplasmic nitrate reductase NapA is the only respiratory nitrate reductase in W. succinogenes, although a second nitrate-reducing enzyme is apparently induced in the napA mutant. The nap cluster of W. succinogenes lacks a napC gene whose product is thought to function in quinol oxidation and electron transfer to NapA in other bacteria. The W. succinogenes genome encodes two members of the NapC/NirT family, NrfH and FccC. Characterization of corresponding deletion mutants indicates that neither of these two proteins is required for nitrate respiration. A mutant lacking the genes encoding respiratory nitrite reductase (nrfHA) had wild-type properties with respect to nitrate respiration. A model of the electron transport chain of nitrate respiration is proposed in which one or more of the napF, G, H and L gene products mediate electron transport from menaquinol to the periplasmic NapAB complex. Inspection of the W. succinogenes genome sequence suggests that ammonia formation from

  5. Podpora MS-NAP pro systém AVG

    OpenAIRE

    Kuchta, Ondřej

    2011-01-01

    Tato bakalářská práce se zabývá návrhem a implementací podpory technologie NAP společnosti Microsoft do antivirového produktu AVG společnosti AVG Technologies. Začátek práce obecně popisuje architekturu technologie NAP a možností jejího nasazení. Dále se práce zabývá návrhem a implementací klientské i serverové části podpory NAP pro antivir společnosti AVG. Výsledkem je ucelená práce pojednávající o implementaci a nasazení NAP do produktů třetích stran. This bachelor thesis deals with...

  6. Practice and nap schedules modulate children's motor learning.

    Science.gov (United States)

    Ren, Jie; Guo, Wei; Yan, Jin H; Liu, Guanmin; Jia, Fujun

    2016-01-01

    Night- or day-time sleep enhances motor skill acquisition. However, prominent issues remained about the circadian (time-of-day) and homeostatic (time since last sleep) effects of sleep on developmental motor learning. Therefore, we examined the effects of nap schedules and nap-test-intervals (NTIs) on the learning of finger tapping sequences on computer keyboards. Children aged 6-7, 8-9, and 10-11 years explicitly acquired the short and long tapping orders that share the same movement strings (4-2-3-1-4, 4-2-3-1-4-2-3-1-4). Following a constant 8- or 10-hr post-learning period in one of the four NTIs (2, 4, 5, 7 hr), children in the morning napping groups, the afternoon napping groups, or the waking group performed the original long sequence in retention test (4-2-3-1-4-2-3-1-4) and the mirrored-order sequence in transfer test (1-3-2-4-1-3-2-4-1). Age and treatment differences in the movement time (MT, ms) and sequence accuracy (SA, %) were compared during skill learning and in retrieval tests. Results suggest that practice or nap affects MT and SA in a greater extent for the younger learners than for the older learners. The circadian effects might not change nap-based skill learning. Importantly, the longer NTIs resulted in superior retention performance than the shorter ones, suggesting that children require a relatively longer post-nap period to form motor memory. Finally, nap-based motor learning was more marked in skill retention than in skill transfer. Brain development may play an important role in motor learning. Our discussion centers on memory consolidation and its relevance for skill acquisition from early to late childhood.

  7. CHAOS-a model of the Earth's magnetic field derived from CHAMP, Orsted, and SAC-C magnetic satellite data

    DEFF Research Database (Denmark)

    Olsen, Nils; Luhr, H.; Sabaka, T.J.;

    2006-01-01

    We have derived a model of the near-Earth magnetic field (up to spherical harmonic degree n= 50 for the static field, and up to n = 18 for the first time derivative) using more than 6.5 yr of high-precision geomagnetic measurements from the three satellites Orsted, CHAMP and SAC-C taken between...

  8. GPS radio occultation with CHAMP and SAC-C: global monitoring of thermal tropopause parameters

    Directory of Open Access Journals (Sweden)

    T. Schmidt

    2005-01-01

    Full Text Available In this study the global lapse-rate tropopause (LRT pressure, temperature, potential temperature, and sharpness are discussed based on Global Positioning System (GPS radio occultations (RO from the German CHAMP (CHAllenging Minisatellite Payload and the U.S.-Argentinian SAC-C (Satelite de Aplicaciones Cientificas-C satellite missions. Results with respect to seasonal variations are compared with operational radiosonde data and ECMWF (European Centre for Medium-Range Weather Forecast operational analyses. Results on the tropical quasi-biennial oscillation (QBO are updated from an earlier study. CHAMP RO data are available continuously since May 2001 with on average 150 high resolution temperature profiles per day. SAC-C data are available for several periods in 2001 and 2002. In this study temperature data from CHAMP for the period May 2001-December 2004 and SAC-C data from August 2001-October 2001 and March 2002-November 2002 were used, respectively. The bias between GPS RO temperature profiles and radiosonde data was found to be less than 1.5K between 300 and 10hPa with a standard deviation of 2-3K. Between 200-20hPa the bias is even less than 0.5K (2K standard deviation. The mean deviations based on 167699 comparisons between CHAMP/SAC-C and ECMWF LRT parameters are (-2.1±37.1hPa for pressure and (0.1±4.2K for temperature. Comparisons of LRT pressure and temperature between CHAMP and nearby radiosondes (13230 resulted in (5.8±19.8hPa and (-0.1±3.3K, respectively. The comparisons between CHAMP/SAC-C and ECMWF show on average the largest differences in the vicinity of the jet streams with up to 700m in LRT altitude and 3K in LRT temperature, respectively. The CHAMP mission generates the first long-term RO data set. Other satellite missions will follow (GRACE, COSMIC, MetOp, TerraSAR-X, EQUARS generating together some thousand temperature profiles daily.

  9. MECHANISM OF FUSARIUM TRICINCTUM (CORDA SACC. SPORE INACTIVATION BY CHLORINE DIOXIDE

    Directory of Open Access Journals (Sweden)

    Zhao Chen

    2015-06-01

    Full Text Available The mechanism of Fusarium tricinctum (Corda Sacc. spore inactivation by chlorine dioxide (ClO2 was investigated. During F. tricinctum spore inactivation by ClO2, protein, DNA, and metal ion leakage, enzyme activity, and cell ultrastructure were examined. Protein and DNA leakages were not detected, while there were metal ion leakages of K+, Ca2+, and Mg2+, which were well-correlated with the inactivation rate. The enzyme activities of glucose-6-phosphate dehydrogenase, citrate synthase, and phosphofructokinase were inhibited and were also well-correlated with the inactivation rate. Electron micrographs showed the ultrastructural modifications of spores and demonstrated that spores were heavily distorted and collapsed from their regular structure. Spore surface damage and disruption in inner components was also severe. The metal ion leakage, the inhibition of enzyme activities, and the damage of spore structure were significant in F. tricinctum spore inactivation by ClO2.

  10. Isolation and fusion of protoplasts from the phytopathogenic fungus Sclerotium rolfsii (Sacc.

    Directory of Open Access Journals (Sweden)

    Sikandar Hayat

    2010-03-01

    Full Text Available Sclerotium rolfsii (Sacc. is a serious plant pathogenic fungus and lacks perfect (basidial stage in production. Protoplast fusion technology was employed to reconstruct fusants from this fungus. Two strains designated as A and R were used. Maximum protoplast yields of 3.8x10(5 /g mycelia and 2.8x10(5 /g mycelia were formed in strains A and R respectively. Osmotic stabilizer sucrose 1M gave maximum yield. Lysing enzyme at the rate of 15mg/ml was found best for yield. Fusion of protoplasts from strains A and R was carried out in fusion media containing PEG 4000 30% (w/v with 0.2mM CaCl2. Four fusants F1, F2, F3 and F4 were recovered. Morphological, physiological and pathogenic characters of fusants were compared with parent strains on carrots, beans and tomato.

  11. Effectiveness of some microorganisms in the limitation of grapevine cuttings infection by Phomopsis viticola Sacc.

    Directory of Open Access Journals (Sweden)

    Ewa Król

    2013-12-01

    Full Text Available The possibilities of using antagonistic fungi and bacteria in the limitation of grapevine stems infection by Phomopsis viticola Sacc. were studied. Trichodema koningii Oud., T.viride Persoon ex S.F.,T.harzianum Rifai, Gliocladium catenulatum Gilman and Abbott, G.fimbriatum Gilman and Abbott, Bacillus sp., Pseudomonas fluorescens and five unidentified isolates of bacteria i.e.: 22a, 35, 40, 45, 66 were estimated. It was appeared what Trichoderma spp. were the most effective in protection of grapevine stems against the infection by P.viticola. After these antagonistic fungi were used on protected grapevine canes not numerous necrosis were observed and few cultures of pathogen were reisolated from them. Moreover, Trichoderma spp. survived on the grapevine stems during the period of experiment. The abilities of other microorganisms tested to protect grapevine cuttings against P.viticola infection and to exist on the stems were less than Trichoderma spp.

  12. Molecular evolution and species-specific expansion of the NAP members in plants

    Institute of Scientific and Technical Information of China (English)

    Kai Fan,; Hao Shen,; Noreen Bibi,; Feng Li,; Shuna Yuan,; Ming Wang; Xuede Wang

    2015-01-01

    The NAP (NAC-Like, Activated by AP3/PI) subfamily is one of the important plant-specific transcription factors, and controls many vital biological processes in plants. In the current study, 197 NAP proteins were identified from 31 vascular plants, but no NAP members were found in eight non-vascular plants. Al NAP proteins were phylogenetical y classified into two groups (NAP I and NAP II), and the origin time of the NAP I group might be relatively later than that of the NAP II group. Furthermore, species-specific gene duplications, caused by segmental duplication events, resulted in the expansion of the NAP subfamily after species-divergence. Different groups have different expansion rates, and the NAP group preference was found during the expansion in plants. Moreover, the expansion of NAP proteins may be related to the gain and loss of introns. Besides, functional divergence was limited after the gene duplication. Abscisic acid (ABA) might play an important role in leaf senescence, which is regulated by NAP subfamily. These results could lay an important foundation for expansion and evolutionary analysis of NAP subfamily in plants.

  13. Use of NAP gene to manipulate leaf senescence in plants

    Science.gov (United States)

    Gan, Susheng; Guo, Yongfeng

    2013-04-16

    The present invention discloses transgenic plants having an altered level of NAP protein compared to that of a non-transgenic plant, where the transgenic plants display an altered leaf senescence phenotype relative to a non-transgenic plant, as well as mutant plants comprising an inactivated NAP gene, where mutant plants display a delayed leaf senescence phenotype compared to that of a non-mutant plant. The present invention also discloses methods for delaying leaf senescence in a plant, as well as methods of making a mutant plant having a decreased level of NAP protein compared to that of a non-mutant plant, where the mutant plant displays a delayed leaf senescence phenotype relative to a non-mutant plant. Methods for causing precocious leaf senescence or promoting leaf senescence in a plant are also disclosed. Also disclosed are methods of identifying a candidate plant suitable for breeding that displays a delayed leaf senescence and/or enhanced yield phenotype.

  14. Pengaruh Gliocladium virens dan Varietas Terhadap Perkembangan Penyakit Fusarium oxysporum f.sp lycopersici (Sacc) Pada Tanaman Tomat (Lycopersicum esculentum Smith) di Lapangan

    OpenAIRE

    Kirnando, Afriando Flora

    2011-01-01

    Afriando Flora Kirnando, “The Gliocladium virens and variety effect to the development of Fusarium oxysporum f.sp lycopersici (Sacc) disease in tomato plants in the field”, supervisor by Mukhtar Iskandar Pinem and Lahmuddin Lubis. Many control maesures have been done to suppress developing of Fusarium oxysporum f.sp lycopersici (Sacc) but have not succesful, so that one of alternative with biological control. Research aimed to The Gliocladium virens and variety effect to the development of ...

  15. A global model of mantle conductivity derived from 5 years of CHAMP, Orsted, and SAC-C magnetic data

    DEFF Research Database (Denmark)

    Kuvshinov, A.; Olsen, Nils

    2006-01-01

    We present a global 1-D conductivity model which is obtained by analysis of five years ( 2001 - 2005) of simultaneous magnetic data from the three satellites Orsted, CHAMP and SAC-C. After removal of core and crustal fields as predicted by a recent field model we used non-polar scalar and vector...... model which is rather similar to models derived from ground-based data....

  16. Rapid descriptive sensory methods – Comparison of Free Multiple Sorting, Partial Napping, Napping, Flash Profiling and conventional profiling

    DEFF Research Database (Denmark)

    Dehlholm, Christian; Brockhoff, Per B.; Meinert, Lene;

    2012-01-01

    Two new rapid descriptive sensory evaluation methods are introduced to the field of food sensory evaluation. The first method, free multiple sorting, allows subjects to perform ad libitum free sortings, until they feel that no more relevant dissimilarities among products remain. The second method...... is a modal restriction of Napping to specific sensory modalities, directing sensation and still allowing a holistic approach to products. The new methods are compared to Flash Profiling, Napping and conventional descriptive sensory profiling. Evaluations are performed by several panels of expert assessors...

  17. Electrocatalytic reduction of nitrate and selenate by NapAB.

    Science.gov (United States)

    Gates, Andrew J; Butler, Clive S; Richardson, David J; Butt, Julea N

    2011-01-01

    Bacterial cellular metabolism is renowned for its metabolic diversity and adaptability. However, certain environments present particular challenges. Aerobic metabolism of highly reduced carbon substrates by soil bacteria such as Paracoccus pantotrophus presents one such challenge since it may result in excessive electron delivery to the respiratory redox chain when compared with the availability of terminal oxidant, O2. The level of a periplasmic ubiquinol-dependent nitrate reductase, NAP, is up-regulated in the presence of highly reduced carbon substrates. NAP oxidizes ubiquinol at the periplasmic face of the cytoplasmic membrane and reduces nitrate in the periplasm. Thus its activity counteracts the accumulation of excess reducing equivalents in ubiquinol, thereby maintaining the redox poise of the ubiquinone/ubiquinol pool without contributing to the protonmotive force across the cytoplasmic membrane. Although P. pantotrophus NapAB shows a high level of substrate specificity towards nitrate, the enzyme has also been reported to reduce selenate in spectrophotometric solution assays. This transaction draws on our current knowledge concerning the bacterial respiratory nitrate reductases and extends the application of PFE (protein film electrochemistry) to resolve and quantify the selenate reductase activity of NapAB. PMID:21265780

  18. Delayed benefit of naps on motor learning in preschool children.

    Science.gov (United States)

    Desrochers, Phillip C; Kurdziel, Laura B F; Spencer, Rebecca M C

    2016-03-01

    Sleep benefits memory consolidation across a variety of domains in young adults. However, while declarative memories benefit from sleep in young children, such improvements are not consistently seen for procedural skill learning. Here we examined whether performance improvements on a procedural task, although not immediately observed, are evident after a longer delay when augmented by overnight sleep (24 h after learning). We trained 47 children, aged 33-71 months, on a serial reaction time task and, using a within-subject design, evaluated performance at three time points: immediately after learning, after a daytime nap (nap condition) or equivalent wake opportunity (wake condition), and 24 h after learning. Consistent with previous studies, performance improvements following the nap did not differ from performance improvements following an equivalent interval spent awake. However, significant benefits of the nap were found when performance was assessed 24 h after learning. This research demonstrates that motor skill learning is benefited by sleep, but that this benefit is only evident after an extended period of time.

  19. First report of Clostridium difficile NAP1/027 in a Mexican hospital.

    Directory of Open Access Journals (Sweden)

    Adrián Camacho-Ortiz

    Full Text Available Clostridium difficile NAP1/ribotype 027 is associated with severe disease and high mortality rates. Our aim was to determine the prevalence of NAP1/ribotype 027 among C. difficile isolates in a tertiary care hospital, and review the main clinical data.We included 106 stool samples from 106 patients. Samples were tested for A&B toxins and were cultured on CCFA agar. The genes tcdA, tcdB, tcdC, cdtA, and cdtB were amplified using PCR in clinical isolates. The tcdA 3'-end deletion analysis, PCR-ribotyping, and pulsed-field gel electrophoresis (PFGE were also performed. Stool samples that were positive for culture were tested by the GeneXpert C. difficile assay. Clinical data were collected.Thirty-six patients tested positive for A&B toxins; and 22 patients had positive culture for C. difficile, 14 of which tested positive for the A&B toxins and all 22 patients tested positive by the GeneXpert C. difficile assay. Risk factors included an average hospital stay of 16.1 days prior to toxin detection, average antibiotic use for 16.2 days, and a median of 3 antibiotics used. The 30-day crude mortality rate was 8.4%. Six of the 22 patients died, and 3 of those deaths were directly attributed to C. difficile infection. The majority of isolates, 90.9% (20/22, carried genes tcdB, tcdA, cdtA, and cdtB; and these strains carried the corresponding downregulator gene tcdC, with an 18-bp deletion. PFGE was performed on 17 isolates, and one main pattern was observed. Analysis of the ribotyping data showed similar results.The above findings represent the clonal spread of C. difficile in our institution, which mainly includes the NAP1/027 strain. This is the first report of C. difficile ribotype NAP1/027 in Mexico.

  20. Teamwork in Acute Care: Perceptions of Essential but Unheard Assistive Personnel and the Counterpoint of Perceptions of Registered Nurses.

    Science.gov (United States)

    Bellury, Lanell; Hodges, Helen; Camp, Amanda; Aduddell, Kathie

    2016-10-01

    Teams of unlicensed personnel and registered nurses have provided hospital-based nursing care for decades. Although ineffective teamwork has been associated with poor patient outcomes, little is known of the perspectives of nursing assistive personnel (NAP). The purpose of this study was to gain insights into the perceptions of NAP and professional registered nurses (RNs) on teamwork in acute care. In a qualitative descriptive approach in a metropolitan hospital in the southeastern United States, 33 NAP participated in audio-recorded focus group sessions, and 18 RNs provided responses to open-ended electronic survey questions. Findings were examined in relation to previously identified coordinating mechanisms of teamwork: shared mental models, closed-loop communication, and mutual trust. None of the mechanisms was strongly represented in these data. In contrast to RNs' mental models, NAP perceptions of teamwork included the centrality of holistic caring to the NAP role, functional teams as NAP-only teams, NAPs and RNs working in parallel spheres rather than together, and team coordination in silos. Closed-loop communication was less common than one-way requests. Mutual trust was desired, but RNs' delegation of tasks conveyed to NAP a lack of value and respect for the NAP role, while RNs perceived a professional obligation to delegate care to ensure quality of care amid changing patient priorities. Further empirical research into NAP practice is needed to enhance understanding of teamwork issues and direct effective interventions to improve work environments and ultimately patient outcomes. © 2016 Wiley Periodicals, Inc. PMID:27305338

  1. Teamwork in Acute Care: Perceptions of Essential but Unheard Assistive Personnel and the Counterpoint of Perceptions of Registered Nurses.

    Science.gov (United States)

    Bellury, Lanell; Hodges, Helen; Camp, Amanda; Aduddell, Kathie

    2016-10-01

    Teams of unlicensed personnel and registered nurses have provided hospital-based nursing care for decades. Although ineffective teamwork has been associated with poor patient outcomes, little is known of the perspectives of nursing assistive personnel (NAP). The purpose of this study was to gain insights into the perceptions of NAP and professional registered nurses (RNs) on teamwork in acute care. In a qualitative descriptive approach in a metropolitan hospital in the southeastern United States, 33 NAP participated in audio-recorded focus group sessions, and 18 RNs provided responses to open-ended electronic survey questions. Findings were examined in relation to previously identified coordinating mechanisms of teamwork: shared mental models, closed-loop communication, and mutual trust. None of the mechanisms was strongly represented in these data. In contrast to RNs' mental models, NAP perceptions of teamwork included the centrality of holistic caring to the NAP role, functional teams as NAP-only teams, NAPs and RNs working in parallel spheres rather than together, and team coordination in silos. Closed-loop communication was less common than one-way requests. Mutual trust was desired, but RNs' delegation of tasks conveyed to NAP a lack of value and respect for the NAP role, while RNs perceived a professional obligation to delegate care to ensure quality of care amid changing patient priorities. Further empirical research into NAP practice is needed to enhance understanding of teamwork issues and direct effective interventions to improve work environments and ultimately patient outcomes. © 2016 Wiley Periodicals, Inc.

  2. Effects of afternoon "siesta" naps on sleep, alertness, performance, and circadian rhythms in the elderly

    Science.gov (United States)

    Monk, T. H.; Buysse, D. J.; Carrier, J.; Billy, B. D.; Rose, L. R.

    2001-01-01

    STUDY OBJECTIVES: To determine the effects of a 90-minute afternoon nap regimen on nocturnal sleep, circadian rhythms, and evening alertness and performance levels in the healthy elderly. DESIGN AND SETTING: Nine healthy elderly subjects (4m, 5f, age range 74y-87y) each experienced both nap and no-nap conditions in two studies each lasting 17 days (14 at home, 3 in the laboratory). In the nap condition a 90-minute nap was enforced between 13:30 and 15:00 every day, in the no-nap condition daytime napping was prohibited, and activity encouraged in the 13:30-15:00 interval. The order of the two conditions was counterbalanced. PARTICIPANTS: N/A INTERVENTIONS: N/A MEASUREMENTS: Diary measures, pencil and paper alertness tests, and wrist actigraphy were used at home. In the 72 hour laboratory studies, these measures were augmented by polysomnographic sleep recording, continuous rectal temperature measurement, a daily evening single trial of a Multiple Sleep Latency Test (MSLT), and computerized tests of mood, activation and performance efficiency. RESULTS: By the second week in the "at home" study, an average of 58 minutes of sleep was reported per siesta nap; in the laboratory, polysomnography confirmed an average of 57 minutes of sleep per nap. When nap and no-nap conditions were compared, mixed effects on nocturnal sleep were observed. Diary measures indicated no significant difference in nocturnal sleep duration, but a significant increase (of 38 mins.) in 24-hour Total Sleep Time (TST) when nocturnal sleeps and naps were added together (psleep efficiency in the nap condition (pSleep Time (TST) by 48 mins. in the nap condition (peffects on Wake After Sleep Onset (WASO), delta sleep measures, or percent stages 1 & 2. Unlike the diary study, the laboratory study yielded no overall increase in 24-hour TST consequent upon the siesta nap regimen. The only measure of evening alertness or performance to show an improvement was sleep latency in a single-trial evening MSLT

  3. Effects of afternoon "siesta" naps on sleep, alertness, performance, and circadian rhythms in the elderly

    Science.gov (United States)

    Monk, T. H.; Buysse, D. J.; Carrier, J.; Billy, B. D.; Rose, L. R.

    2001-01-01

    STUDY OBJECTIVES: To determine the effects of a 90-minute afternoon nap regimen on nocturnal sleep, circadian rhythms, and evening alertness and performance levels in the healthy elderly. DESIGN AND SETTING: Nine healthy elderly subjects (4m, 5f, age range 74y-87y) each experienced both nap and no-nap conditions in two studies each lasting 17 days (14 at home, 3 in the laboratory). In the nap condition a 90-minute nap was enforced between 13:30 and 15:00 every day, in the no-nap condition daytime napping was prohibited, and activity encouraged in the 13:30-15:00 interval. The order of the two conditions was counterbalanced. PARTICIPANTS: N/A INTERVENTIONS: N/A MEASUREMENTS: Diary measures, pencil and paper alertness tests, and wrist actigraphy were used at home. In the 72 hour laboratory studies, these measures were augmented by polysomnographic sleep recording, continuous rectal temperature measurement, a daily evening single trial of a Multiple Sleep Latency Test (MSLT), and computerized tests of mood, activation and performance efficiency. RESULTS: By the second week in the "at home" study, an average of 58 minutes of sleep was reported per siesta nap; in the laboratory, polysomnography confirmed an average of 57 minutes of sleep per nap. When nap and no-nap conditions were compared, mixed effects on nocturnal sleep were observed. Diary measures indicated no significant difference in nocturnal sleep duration, but a significant increase (of 38 mins.) in 24-hour Total Sleep Time (TST) when nocturnal sleeps and naps were added together (psleep efficiency in the nap condition (preduction of nocturnal Total Sleep Time (TST) by 48 mins. in the nap condition (pSleep Onset (WASO), delta sleep measures, or percent stages 1 & 2. Unlike the diary study, the laboratory study yielded no overall increase in 24-hour TST consequent upon the siesta nap regimen. The only measure of evening alertness or performance to show an improvement was sleep latency in a single-trial evening

  4. Eficiencia biológica de cepas nativas de Trichoderma spp., en el control de Sclerotium rolfsii Sacc., en cacahuate

    OpenAIRE

    A. C. Michel-Aceves; M. A. Otero-Sánchez; R. Ariza-Flores; A. Barrios-Ayala; N. Alarcón-Cruz

    2013-01-01

    En el control de Sclerotium rolfsii Sacc., se evaluó el efecto antagónico de aislados nativos de Trichoderma spp., bajo condiciones in vitro y de invernadero, en la zona Norte del estado de Guerrero. Se obtuvieron doce aislados nativos de Trichoderma spp. (dos de Santa Teresa y diez de Tlaxmalac, Gro.), de los cuales se seleccionaron seis (Tcn-4, Tcn-5, Tcn-6, Tcn-7, Tcn-8 y Tcn-11) mediante el método del papel celofán. En condiciones in vitro, el porcentaje de inhibición varió desde 10 a 94....

  5. The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution

    Science.gov (United States)

    Bowman, Andrew; Hammond, Colin M.; Stirling, Andrew; Ward, Richard; Shang, Weifeng; El-Mkami, Hassane; Robinson, David A.; Svergun, Dmitri I.; Norman, David G.; Owen-Hughes, Tom

    2014-01-01

    NAP-1 fold histone chaperones play an important role in escorting histones to and from sites of nucleosome assembly and disassembly. The two NAP-1 fold histone chaperones in budding yeast, Vps75 and Nap1, have previously been crystalized in a characteristic homodimeric conformation. In this study, a combination of small angle X-ray scattering, multi angle light scattering and pulsed electron–electron double resonance approaches were used to show that both Vps75 and Nap1 adopt ring-shaped tetrameric conformations in solution. This suggests that the formation of homotetramers is a common feature of NAP-1 fold histone chaperones. The tetramerisation of NAP-1 fold histone chaperones may act to shield acidic surfaces in the absence of histone cargo thus providing a ‘self-chaperoning’ type mechanism. PMID:24688059

  6. The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution

    OpenAIRE

    Bowman, A.; Hammond, C. M.; Stirling, A.; Ward, R.; Shang, W.; El-Mkami, H.; Robinson, D A; Svergun, Dmitri; Norman, D. G.; Owen-Hughes, T.

    2014-01-01

    MRC [G1100021]; Wellcome Senior Fellowship [095062]. Source of open access funding: The Wellcome Trust [094090]. NAP-1 fold histone chaperones play an important role in escorting histones to and from sites of nucleosome assembly and disassembly. The two NAP-1 fold histone chaperones in budding yeast, Vps75 and Nap1, have previously been crystalized in a characteristic homodimeric conformation. In this study, a combination of small angle X-ray scattering, multi angle light scattering and pu...

  7. The ADNP derived peptide, NAP modulates the tubulin pool: implication for neurotrophic and neuroprotective activities.

    Directory of Open Access Journals (Sweden)

    Saar Oz

    Full Text Available Microtubules (MTs, key cytoskeletal elements in living cells, are critical for axonal transport, synaptic transmission, and maintenance of neuronal morphology. NAP (NAPVSIPQ is a neuroprotective peptide derived from the essential activity-dependent neuroprotective protein (ADNP. In Alzheimer's disease models, NAP protects against tauopathy and cognitive decline. Here, we show that NAP treatment significantly affected the alpha tubulin tyrosination cycle in the neuronal differentiation model, rat pheochromocytoma (PC12 and in rat cortical astrocytes. The effect on tubulin tyrosination/detyrosination was coupled to increased MT network area (measured in PC12 cells, which is directly related to neurite outgrowth. Tubulin beta3, a marker for neurite outgrowth/neuronal differentiation significantly increased after NAP treatment. In rat cortical neurons, NAP doubled the area of dynamic MT invasion (Tyr-tubulin into the neuronal growth cone periphery. NAP was previously shown to protect against zinc-induced MT/neurite destruction and neuronal death, here, in PC12 cells, NAP treatment reversed zinc-decreased tau-tubulin-MT interaction and protected against death. NAP effects on the MT pool, coupled with increased tau engagement on compromised MTs imply an important role in neuronal plasticity, protecting against free tau accumulation leading to tauopathy. With tauopathy representing a major pathological hallmark in Alzheimer's disease and related disorders, the current findings provide a mechanistic basis for further development. NAP (davunetide is in phase 2/3 clinical trial in progressive supranuclear palsy, a disease presenting MT deficiency and tau pathology.

  8. Hiiumaa kiviajast tänapäevani / Endel Saar

    Index Scriptorium Estoniae

    Saar, Endel

    2001-01-01

    Järg Feb/10;17 Mar/3;10;17;24;31 Apr/7;21;28 May/5;26 Jun/2;9;16;30 Jul/7;14;21;28 Aug/4;11;18;25 Sep/8 ;15;22;29 Oct/6;13;20;27 Nov/3;10;24 Dec/1;8;15;22;29. Biosfääri Kaitseala Keskuse poolt koostatud atlas "Administratiivsete muutuste ülevaatekaart", kus antakse ülevaade Hiiumaa arenguloost kiviajast tänapäevani

  9. Proposal to conserve the name Phomopsis citri H.S. Fawc. (Diaporthe citri), with a conserved type, against Phomopsis citri (Sacc.) Traverso & Spessa (Ascomycota, Diaporthales, Diaporthaceae)

    Science.gov (United States)

    The name Diaporthe citri applies to a fungus that causes a disease on Citrus known as melanose or stem end rot of mature fruit after harvest and occurs widely in North America and Asia. Initially described as the illegitimate Phomopsis citri H.S. Fawc. 1912, non P. citri (Sacc.) Traverso & Spessa 19...

  10. CM5, a pre-Swarm comprehensive geomagnetic field model derived from over 12 yr of CHAMP, Ørsted, SAC-C and observatory data

    DEFF Research Database (Denmark)

    Sabaka, Terence J.; Olsen, Nils; Tyler, Robert H.;

    2015-01-01

    A comprehensive magnetic field model named CM5 has been derived from CHAMP, Orsted and SAC-C satellite and observatory hourly-means data from 2000 August to 2013 January using the Swarm Level-2 Comprehensive Inversion (CI) algorithm. Swarm is a recently launched constellation of three satellites ...

  11. Nap-titration : An effective alternative for continuous positive airway pressure titration

    NARCIS (Netherlands)

    Hoekema, A; Stegenga, B; Meinesz, AF; van der Hoeven, JH; Wijkstra, PJ

    2006-01-01

    When treating Obstructive Steep Apnea-Hypopnea Syndrome (OSAHS) several alternatives for standard (manual) continuous positive airway pressure (CPAP) titration are feasible. A practical alternative is titration without polysomnography during an afternoon nap (Nap-titration). The aim of the present s

  12. Naps in school can enhance the duration of declarative memories learned by adolescents

    Directory of Open Access Journals (Sweden)

    Nathalia eLemos

    2014-06-01

    Full Text Available Sleep helps the consolidation of declarative memories in the laboratory, but the pro-mnemonic effect of daytime naps in schools is yet to be fully characterized. While a few studies indicate that sleep can indeed benefit school learning, it remains unclear how best to use it. Here we set out to evaluate the influence of daytime naps on the duration of declarative memories learned in school by students of 10-15 years old. A total of 584 students from 6th grade were investigated. Students within a regular classroom were exposed to a 15-minute lecture on new declarative contents, absent from the standard curriculum for this age group. The students were then randomly sorted into nap and non-nap groups. Students in the nap group were conducted to a quiet room with mats, received sleep masks and were invited to sleep. At the same time, students in the non-nap group attended regular school classes given by their usual teacher (Experiment I, or English classes given by another experimenter (Experiment II. In Experiment I (n=371, students were pre-tested on lecture-related contents before the lecture, were invited to nap for up to 2 hours, and after 1, 2 or 5 days received surprise tests with similar content but different wording and question order. In Experiment II (n=213, students were invited to nap for up to 50 minutes (duration of a regular class; surprise tests were applied immediately after the lecture, and repeated after 5, 30 or 110 days. Experiment I showed a significant ~10% gain in test scores for both nap and non-nap groups 1 day after learning, in comparison with pre-test scores. This gain was sustained in the nap group after 2 and 5 days, but in the non-nap group it decayed completely after 5 days. In Experiment II, the nap group showed significantly higher scores than the non-nap group at all times tested, thus precluding specific conclusions. The results suggest that sleep can be used to enhance the duration of memory contents learned in

  13. Sleep to the beat: A nap favours consolidation of timing.

    Science.gov (United States)

    Verweij, Ilse M; Onuki, Yoshiyuki; Van Someren, Eus J W; Van der Werf, Ysbrand D

    2016-06-01

    Growing evidence suggests that sleep is important for procedural learning, but few studies have investigated the effect of sleep on the temporal aspects of motor skill learning. We assessed the effect of a 90-min day-time nap on learning a motor timing task, using 2 adaptations of a serial interception sequence learning (SISL) task. Forty-two right-handed participants performed the task before and after a 90-min period of sleep or wake. Electroencephalography (EEG) was recorded throughout. The motor task consisted of a sequential spatial pattern and was performed according to 2 different timing conditions, that is, either following a sequential or a random temporal pattern. The increase in accuracy was compared between groups using a mixed linear regression model. Within the sleep group, performance improvement was modeled based on sleep characteristics, including spindle- and slow-wave density. The sleep group, but not the wake group, showed improvement in the random temporal, but especially and significantly more strongly in the sequential temporal condition. None of the sleep characteristics predicted improvement on either general of the timing conditions. In conclusion, a daytime nap improves performance on a timing task. We show that performance on the task with a sequential timing sequence benefits more from sleep than motor timing. More important, the temporal sequence did not benefit initial learning, because differences arose only after an offline period and specifically when this period contained sleep. Sleep appears to aid in the extraction of regularities for optimal subsequent performance. (PsycINFO Database Record PMID:27214501

  14. Duration of sleep inertia after napping during simulated night work and in extended operations.

    Science.gov (United States)

    Signal, Tracey Leigh; van den Berg, Margo J; Mulrine, Hannah M; Gander, Philippa H

    2012-07-01

    Due to the mixed findings of previous studies, it is still difficult to provide guidance on how to best manage sleep inertia after waking from naps in operational settings. One of the few factors that can be manipulated is the duration of the nap opportunity. The aim of the present study was to investigate the magnitude and time course of sleep inertia after waking from short (20-, 40- or 60-min) naps during simulated night work and extended operations. In addition, the effect of sleep stage on awakening and duration of slow wave sleep (SWS) on sleep inertia was assessed. Two within-subject protocols were conducted in a controlled laboratory setting. Twenty-four healthy young men (Protocol 1: n = 12, mean age = 25.1 yrs; Protocol 2: n = 12, mean age = 23.2 yrs) were provided with nap opportunities of 20-, 40-, and 60-min (and a control condition of no nap) ending at 02:00 h after ∼20 h of wakefulness (Protocol 1 [P1]: simulated night work) or ending at 12:00 h after ∼30 h of wakefulness (Protocol 2 [P2]: simulated extended operations). A 6-min test battery, including the Karolinska Sleepiness Scale (KSS) and the 4-min 2-Back Working Memory Task (WMT), was repeated every 15 min the first hour after waking. Nap sleep was recorded polysomnographically, and in all nap opportunities sleep onset latency was short and sleep efficiency high. Mixed-model analyses of variance (ANOVA) for repeated measures were calculated and included the factors time (time post-nap), nap opportunity (duration of nap provided), order (order in which the four protocols were completed), and the interaction of these terms. Results showed no test x nap opportunity effect (i.e., no effect of sleep inertia) on KSS. However, WMT performance was impaired (slower reaction time, fewer correct responses, and increased omissions) on the first test post-nap, primarily after a 40- or 60-min nap. In P2 only, performance improvement was evident 45 min post-awakening for naps of 40 min or more. In ANOVAs

  15. Coordinated Action of Nap1 and RSC in Disassembly of Tandem Nucleosomes.

    Science.gov (United States)

    Prasad, Rashmi; D'Arcy, Sheena; Hada, Arjan; Luger, Karolin; Bartholomew, Blaine

    2016-09-01

    The SWI/SNF and RSC family of ATP-dependent chromatin remodelers disassembles nucleosomes by moving nucleosomes into the vicinity of adjoining nucleosomes. We found that the histone chaperone Nap1 efficiently promotes disassembly of adjacent nucleosomes with which RSC collides and not the disassembly of nucleosomes mobilized by RSC. Nap1 is specific to RSC, as it does not target SWI/SNF, its paralog in Saccharomyces cerevisiae Extensive mutational analysis of Nap1 has revealed that Nap1 affinity for histones H2A-H2B and H3-H4 and its ability to displace histones from DNA are required for Nap1 to enhance RSC-mediated disassembly. Other histone chaperones, such as Vps75, that also bind histones are not able to enhance RSC-mediated disassembly. Our study suggests a mechanism by which Nap1 is recruited to actively transcribed regions and assists in the passage of the transcription complex through chromatin, and it provides a novel mechanism for the coordinated action of RSC and Nap1.

  16. Reactive oxygen species and autophagy associated apoptosis and limitation of clonogenic survival induced by zoledronic acid in salivary adenoid cystic carcinoma cell line SACC-83.

    Directory of Open Access Journals (Sweden)

    Xi-Yuan Ge

    Full Text Available Salivary adenoid cystic carcinoma is an epithelial tumor in the head and neck region. Despite its slow growth, patients with salivary adenoid cystic carcinoma exhibit poor long term survival because of a high rate of distant metastasis. Lung and bone are common distant metastasis sites. Zoledronic acid, a third generation bisphosphonate, has been used for tumor-induced osteolysis due to bone metastasis and has direct antitumor activity in several human neoplasms. Here, we observed that zoledronic acid inhibited salivary adenoid cystic carcinoma cell line SACC-83 xenograft tumor growth in nude mice. In vitro, zoledronic acid induced apoptosis and reduced clonogenic survival in SACC-83. Flow cytometry and western blotting indicated that the cell cycle was arrested at G0/G1. Zoledronic acid treatment upregulated reactive oxygen species as well as the autophagy marker protein LC-3B. Reactive oxygen species scavenger N-acetylcysteine and autophagy antagonist 3-methyladenine decreased zoledronic acid-induced apoptosis and increased clonogenic survival. Silencing of the autophagy related gene Beclin-1 also decreased zoledronic acid-induced apoptosis and inhibition of clonogenic formation. In addition, isobolographic analysis revealed synergistic effects on apoptosis when zoledronic acid and paclitaxel/cisplatin were combined. Taken together, our results suggest that zoledronic acid induced apoptosis and reduced clonogenic survival via upregulation of reactive oxygen species and autophagy in the SACC-83 cell line. Thus, zoledronic acid should be considered a promising drug for the treatment of salivary adenoid cystic carcinoma.

  17. [Insomnia symptoms, daytime naps and physical leisure activities in the elderly: FIBRA Study Campinas].

    Science.gov (United States)

    Monteiro, Natália Tonon; Neri, Anita Liberalesso; Coelim, Maria Filomena

    2014-04-01

    The practice of physical activities contributes to reducing the risk of chronic diseases and improves sleep patterns in the elderly. This research aimed to investigate the association between insomnia symptoms and daytime nap and the participation in physical leisure activities in elderly community residents. Data from the Studies Network of the Fragility in Brazilian Elderly (Campinas site), were used. Information from 689 elderly was analyzed, regarding sociodemographic characterization, physical leisure activity, occurrence of daytime napping and its duration, symptoms of insomnia and use of sleep medication. A significant association was found between the practice of walking and the daytime nap of short duration. Studies indicate that a short nap can benefit the quality of sleep and health of the elderly. Therefore, promoting the practice of walking can be a nursing intervention that favors the sleep patterns of the elderly. PMID:24918882

  18. [Insomnia symptoms, daytime naps and physical leisure activities in the elderly: FIBRA Study Campinas].

    Science.gov (United States)

    Monteiro, Natália Tonon; Neri, Anita Liberalesso; Coelim, Maria Filomena

    2014-04-01

    The practice of physical activities contributes to reducing the risk of chronic diseases and improves sleep patterns in the elderly. This research aimed to investigate the association between insomnia symptoms and daytime nap and the participation in physical leisure activities in elderly community residents. Data from the Studies Network of the Fragility in Brazilian Elderly (Campinas site), were used. Information from 689 elderly was analyzed, regarding sociodemographic characterization, physical leisure activity, occurrence of daytime napping and its duration, symptoms of insomnia and use of sleep medication. A significant association was found between the practice of walking and the daytime nap of short duration. Studies indicate that a short nap can benefit the quality of sleep and health of the elderly. Therefore, promoting the practice of walking can be a nursing intervention that favors the sleep patterns of the elderly.

  19. Vanaaegse fototehnikaga katsetamine loob silla mineviku ja tänapäeva vahel / Tanel Verk

    Index Scriptorium Estoniae

    Verk, Tanel

    2013-01-01

    Fototehnika arengust, vanaaegse fototehnika kasutamisest tänapäeval. Eesti Suureformaadilise Fotograafia Ühenduse fotonäitus "Koosolek" Fotomuuseumi galeriis "Lee" 22. novembrist 2012 kuni 14. jaanuarini 2013

  20. The Association between Daytime Napping and Cognitive Functioning in Chronic Fatigue Syndrome

    OpenAIRE

    Gotts, Zoe; Ellis, Jason; Deary, Vincent; Barclay, Nicola; Newton, Julia

    2015-01-01

    OBJECTIVES The precise relationship between sleep and physical and mental functioning in chronic fatigue syndrome (CFS) has not been examined directly, nor has the impact of daytime napping. This study aimed to examine self-reported sleep in patients with CFS and explore whether sleep quality and daytime napping, specific patient characteristics (gender, illness length) and levels of anxiety and depression, predicted daytime fatigue severity, levels of daytime sleepiness and cognitive fun...

  1. napäevased liikursuurtükid / Anna Kern

    Index Scriptorium Estoniae

    Kern, Anna

    2013-01-01

    Riigikaitse arengukavas (a. 2013-2022) on ette nähtud võimalused 1. jalaväebrigaadile hankida tänapäevased liikursuurtükid. Ülevaade liikursuurtükkide loomisest, kasutamisest sõdades ja tänapäevase liikursuurtüki iseloomustus. Näiteid erinevtest liikursuurtükkidest: Archer (Rootsi), Panzerhaubitze 2000 (Saksamaa), Caesar (Prantsusmaa), M777 (USA). Lisatud tabel tehniliste andmetega

  2. Análisis de la infección de Colletotrichum gloeosporioides (Penz. Penz. & Sacc. de frutos de aguacatero

    Directory of Open Access Journals (Sweden)

    Édgar Saúl Rodríguez-López

    2013-09-01

    Full Text Available La patogénesis de Colletotrichum gloeosporioides (Penz. Penz. & Sacc. del estado de Michoacán, México se caracterizó en frutos de aguacatero (Persea americana L. cultivar 'Hass'. El hongo causó los síntomas característicos de la enfermedad denominada 'antracnosis' a partir de los diez días después de la inoculación. La tasa de infección del hongo entre tratamientos fue significativamente diferente (p<0.05 a partir del sexto día de la inoculación y el desarrollo de la enfermedad se explicó por un modelo de regresión lineal simple (Y = 1.123 + 0.1133X. No se detectó la formación de apresorios pero sí la síntesis de una capa mucilaginosa asociada con los tubos germinativos. El proceso infectivo del hongo se manifestó con la penetración de las hifas intra e inter-celularmente y con la producción de acérvulos a partir de los 12 días después de la inoculación. Los síntomas de la antracnosis se asociaron con la degradación de polifenoles, plasmólisis, necrosis y desintegración celular.

  3. Inibição do crescimento micelial de Cercospora calendulae Sacc. por extratos de plantas medicinais

    Directory of Open Access Journals (Sweden)

    J.M. Nascimento

    2013-01-01

    Full Text Available O uso de extratos e óleos essenciais de plantas medicinais tem sido amplamente estudado no controle de doenças de plantas. O objetivo da realização do presente trabalho foi avaliar o efeito de extratos de Ruta graveolens L., Mentha x villosa, Calendula officinalis L., Momordica charantia L., Symphytum officinale L., Ageratum conyzoides L. e Ricinus comunis L., nas concentrações de 0, 250, 500, 1000, 2000, 5000 e 10000 mg L-1, sobre a inibição do crescimento micelial de Cercospora calendulae Sacc. in vitro. Os extratos foram obtidos por infusão. O experimento foi desenvolvido no Laboratório de Fitopatologia da FCA/UFGD, estado de Mato Grosso do Sul, em delineamento inteiramente casualizado, esquema fatorial 7 extratos x 7 concentrações, com seis repetições. Foi detectado efeito dos extratos e suas concentrações sobre o crescimento do fungo, sendo a interação significativa. Os extratos de calêndula, arruda, hortelã e melão de São Caetano, nas maiores concentrações resultaram em maiores porcentagens de inibição, próximas de 100%, 30%, 35% e 40%, respectivamente, a 10000 mg L-1.

  4. Reconsidering the sporulation characteristics of hypervirulent Clostridium difficile BI/NAP1/027.

    Directory of Open Access Journals (Sweden)

    David A Burns

    Full Text Available Clostridium difficile is the leading cause of antibiotic-associated diarrhoea and a major burden to healthcare services worldwide. In recent years, C. difficile strains belonging to the BI/NAP1/027 type have become highly represented among clinical isolates. These so-called 'hypervirulent' strains are associated with outbreaks of increased disease severity, higher relapse rates and an expanded repertoire of antibiotic resistance. Spores, formed during sporulation, play a pivotal role in disease transmission and it has been suggested that BI/NAP1/027 strains are more prolific in terms of sporulation in vitro than 'non-epidemic' C. difficile types. Work in our laboratory has since provided credible evidence to the contrary suggesting that the strain-to-strain variation in C. difficile sporulation characteristics is not type-associated. However, the BI/NAP1/027 type is still widely stated to have an increased rate of sporulation. In this study, we analysed the sporulation rates of 53 C. difficile strains, the largest sample size used to-date in such a study, including 28 BI/NAP1/027 isolates. Our data confirm that significant variation exists in the rate at which different C. difficile strains form spores. However, we clearly show that the sporulation rate of the BI/NAP1/027 type was no higher than that of non-BI/NAP1/027 strains. In addition, we observed substantial variation in sporulation characteristics within the BI/NAP1/027 type. This work highlights the danger of assuming that all strains of one type behave similarly without studying adequate sample sizes. Furthermore, we stress the need for more rigorous experimental procedures in order to quantify C. difficile sporulation more accurately in the future.

  5. Relationship between napping during night shift work and household obligations of female nursing personnel.

    Science.gov (United States)

    Silva-Costa, Aline; Fischer, Frida Marina; Griep, Rosane Harter; Rotenberg, Lúcia

    2013-01-01

    Night shift employment involves displacing sleep to the daytime. For female workers, the opportunity for daytime sleep is influenced by routine housework demands, which aggravates sleep deprivation. Allowing naps to be taken during the night shift of work is a frequent practice at some hospitals and can help reduce the effects of sleep deprivation. We hypothesize that an association between domestic work and the length of naps during night work exists for nursing professionals. To test this hypothesis, two cross-sectional studies were conducted in two different hospitals. In Study 1, female workers answered questionnaires regarding sleeping habits, professional work, and housework demands. In Study 2, data regarding napping during shifts was obtained by actigraphy, a noninvasive method of monitoring the human sleep-wake cycle. The demand for the performance of housework was measured by (i) domestic work hours (total time spent performing domestic work per week), and (ii) domestic workload, which considers the degree of sharing domestic tasks and the number of people living at home. The populations from the two studies were subdivided into groups, based on the duration of napping at work. Data on naps were analyzed according to domestic demands, using the Mann-Whitney and Chi-squared tests. Among the two study populations (Studies 1 and 2), those in Study 2 were older, had shorter professional weekly work hours, worked more night shifts, and dedicated more time to housework. significant associations were only found in Study 2, where greater time napping at work was associated with both greater time spent doing housework and greater domestic workload. The known benefits of napping during night shifts seem to be especially relevant for female workers who are more sleep-deprived from working more night shifts and who have higher demands for housework.

  6. Scientific Opinion on the safety and efficacy of Yea-Sacc® (Saccharomyces cerevisiae as a feed additive for cattle for fattening, goats for fattening, dairy cows, dairy sheep, dairy goats and buffaloes

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP

    2014-05-01

    Full Text Available Yea-Sacc® is an additive based on a live preparation of a strain of Saccharomyces cerevisiae intended for use as a zootechnical additive. It is produced in a powder (Yea-Sacc® and in a prills (Yea-Sacc® TS form. Saccharomyces cerevisiae is considered by EFSA to be suitable for the qualified presumption of safety approach to safety assessment. As the identity of the production strain has been established, safety for the target species, consumer and the environment is presumed. Both formulations are non-irritant to skin, Yea-Sacc® TS is non-irritant to the eye whilst Yea-Sacc® is a moderate irritant. In the absence of data both formulations should be considered skin sensitisers. As both forms are highly proteinaceous, they should be considered as potential respiratory sensitisers. Yea-Sacc® TS is designed to reduce dustiness and no significant exposure of users is to be expected for this form. In the absence of data on the dusting potential of Yea-Sacc®, it would be prudent to treat it as a respiratory sensitiser. Based on the results of four trials Yea-Sacc® was shown to have the potential to increase milk production in dairy cows when supplied at a minimum dose of 5 x 107 CFU/kg complete feed. As the mechanism of action of the additive can be reasonably assumed to be same, efficacy for minor species used for milk production can be presumed when used at the same minimum dose. Yea-Sacc® was also shown to have a potential to improve the production of cattle raised for fattening at a minimum dose of 1 x 108 CFU/kg complete feed. As the mechanism of action of the additive can be reasonably assumed to be same, efficacy for minor ruminant species reared for meat production can be presumed at a minimum dose of 1 x 108 CFU/kg complete feed.

  7. D-SAL and NAP: Two Peptides Sharing a SIP Domain.

    Science.gov (United States)

    Gozes, Illana; Sragovich, Shlomo; Schirer, Yulie; Idan-Feldman, Anat

    2016-06-01

    NAPVSIPQ (NAP) and all D-amino acid SALLRSIPA (D-SAL) are neuroprotective peptides derived from activity-dependent neuroprotective protein (ADNP) and activity-dependent neurotrophic factor (ADNF), respectively. Both proteins were shown to protect against cognitive impairment, using different animal models and to increase neuronal survival following exposure to neurotoxins. NAP was extensively tested and found to increase microtubule stability, protect axonal transport, and inhibit apoptosis. Here, we aimed to further evaluate and correlate effects at the behavioral level, in a rat model of diabetes. Diabetes is primarily a metabolic disorder which presents secondary neurological manifestations. Diabetes induces peripheral nervous system damage which is translated into impaired sensory perception and is termed diabetic neuropathy. Diabetes-related central nervous system damage causes cognitive decline. The behavioral study aimed to evaluate the effect of NAP and D-SAL on peripheral neuropathy and cognitive decline. Peripheral neuropathy was tested by measuring the response to a thermal stimulus, and cognitive ability was measured by a social memory test and a spatial memory test using long- and short-term dependent tasks and a reference memory task. Results indicated an immediate sensory neuropathy in the diabetic model, which was prevented by both peptides and a later neuropathic phase, prevented only by NAP treatment. Cognitive tests revealed impaired performance in both social and spatial memory tests in the diabetes model. Each of the peptides improved different aspects of cognitive behavior, with NAP being more potent than D-SAL. Mechanistically, both NAP and SAL contain a SIP (SxIP) domain that has been shown to interact with microtubule end-binding proteins (EBs). Specifically, we have previously shown a direct interaction of NAP with EB1 and EB3; we have further shown an interaction of the NAP-derived 4 amino acid SKIP peptide with EB3, stimulating axonal

  8. Sleeping pattern of kindergartners and nursery school children: function of daytime nap.

    Science.gov (United States)

    Fukuda, Kazuhiko; Sakashita, Yukine

    2002-02-01

    With a questionnaire answered by parents this study investigated the sleeping pattern of children attending kindergartens or nursery schools and the function of an afternoon nap. Sleeping pattern was investigated by a questionnaire with 441 young children (229 boys and 212 girls) attending kindergartens or nursery schools at the ages of 3 to 6 years old. Nighttime sleep did not show any significant change, while daytime naps decreased drastically and almost disappeared by the age of 6. Nursery school children went to bed later at night, so nighttime sleep was shorter than that of kindergartners. They also reported having more 'difficulty to fall asleep', more frequent 'staying-up at late night', less 'not getting enough sleep', worse 'mood at rising', and more 'unwillingness to go to their schools'. To investigate whether afternoon naps, which are routine at Japanese nursery schools, can compensate for sleep insufficiency on the previous night and whether they have the effect of delaying the onset of the subsequent nighttime sleep, we compared sleep duration on the previous night and the sleep onset time between the days with and without an afternoon nap. The afternoon nap appeared to cause delayed sleep onset but was not a result of sleep deficiency. PMID:11883566

  9. Motor Performance Is not Enhanced by Daytime Naps in Older Adults

    Science.gov (United States)

    Backhaus, Winifried; Braass, Hanna; Renné, Thomas; Gerloff, Christian; Hummel, Friedhelm C.

    2016-01-01

    The impact of sleep on motor learning in the aging brain was investigated using an experimental diurnal nap setup. As the brain ages several components of learning as well as motor performance change. In addition, aging is also related to sleep architectural changes. This combination of slowed learning processes and impaired sleep behavior raises the question of whether sleep can enhance learning and specifically performance of procedural tasks in healthy, older adults. Previous research was able to show sleep-dependent consolidation overnight for numerous tasks in young adults. Some of these study findings can also be replicated for older adults. This study aims to clarify whether sleep-dependent consolidation can also be found during shorter periods of diurnal sleep. The impact of midday naps on motor consolidation was analyzed by comparing procedural learning using a sequence and a motor adaptation task, in a crossover fashion in healthy, non-sleep deprived, older adults randomly subjected to wake (45 min), short nap (10–20 min sleep) or long nap (50–70 min sleep) conditions. Older adults exhibited learning gains, these were not found to be sleep-dependent in either task. The results suggest that daytime naps do not have an impact on performance and motor learning in an aging population. PMID:27303292

  10. Eficiencia biológica de cepas nativas de Trichoderma spp., en el control de Sclerotium rolfsii Sacc., en cacahuate

    Directory of Open Access Journals (Sweden)

    A. C. Michel-Aceves

    2013-01-01

    Full Text Available En el control de Sclerotium rolfsii Sacc., se evaluó el efecto antagónico de aislados nativos de Trichoderma spp., bajo condiciones in vitro y de invernadero, en la zona Norte del estado de Guerrero. Se obtuvieron doce aislados nativos de Trichoderma spp. (dos de Santa Teresa y diez de Tlaxmalac, Gro., de los cuales se seleccionaron seis (Tcn-4, Tcn-5, Tcn-6, Tcn-7, Tcn-8 y Tcn-11 mediante el método del papel celofán. En condiciones in vitro, el porcentaje de inhibición varió desde 10 a 94.40%; registrándose mediante la técnica de cultivos apareados el antagonismo clase dos en el aislado Tcn-11; en estas condiciones, inhibió el crecimiento del fitopatógeno y evitó su desarrollo en el 80% de la superficie del medio en la caja de Petri. En condiciones de invernadero se evaluó la cepa nativa Tcn-11 identificada morfológica y genéticamente como T. harzianum Rifai y se comparó con una cepa de la colección (Thzcf-12 y un fungicida comercial en tres tiempos de inoculación. El fitopatógeno S. rolfsii no fue suficientemente agresivo para ocasionar la muerte de la planta de cacahuate; sin embargo, se observaron efectos negativos en su desarrollo y producción de semillas. Las cepas Tcn-11 y Thzcf-12 fueron capaces de contribuir al desarrollo de la planta de cacahuate y ayudar a protegerla de la infección de S. rolfsii de manera más eficiente que el fungicida pentacloro nitrobenceno (PCNB.

  11. Nucleosome Assembly Protein 1-Like 1 (Nap1l1 Regulates the Proliferation of Murine Induced Pluripotent Stem Cells

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    Yuan Yan

    2016-01-01

    Full Text Available Background/Aims: To investigate whether nucleosome assembly protein 1-like 1 (Nap1l1 regulates the proliferation of induced pluripotent stem cells (iPSC and the potential mechanisms. Methods: Nap1l1-knockdown-iPSC and Nap1l1-overexpression-iPSC were constructed by transfection of lentiviral particles. The proliferation of iPSC was detected by MTT analysis, and cell cycle was analyzed by flow cytometry. Results: Nap1l1 overexpression promoted iPSC proliferation and induced G2/M transition compared to their control iPSC while Nap1l1-knockdown-iPSC dramatically displayed the reduced proliferation and accumulated G2/M phase cells. Further analysis showed that Nap1l1 overexpression in iPSC increased the expression of cyclin B1, downregulated the expression of p21 and p27, while knockdown of Nap1l1 showed the opposite effects. In addition, overexpression of Nap1l1 promoted the phosphorylation of AKT and ERK in iPSC, while knockdown of Nap1l1 inhibited the effects. However, these effects displayed in Nap1l1-overexpression-iPSC were greatly suppressed by the inhibition of AKT or ERK signaling. Conclusions: The results indicate that Nap1l1 promotes the proliferation of iPSC attributable to G2/M transition caused by downregulation of p27 and p21, and upregulation of cyclin B1, the activation of AKT or ERK is involved in the process. The present study has revealed a novel molecular mechanism involved in the proliferation of iPSC.

  12. Perspectivas del uso de bacterias rizosféricas en el control de pyricularia grisea (cooke sacc.) en el cultivo del arroz (oryza sativa l.)

    OpenAIRE

    Acebo Guerrero, Yanelis; Hernández-Rodríguez, Annia; Rives Rodríguez, Narovis; Hernández-Lauzardo, Ana Niurka

    2011-01-01

    Prospect of the use of bacteria in the control Pyricularia grisea (Cooke Sacc.) on rice (Oriza sativa L.) Título corto: Bacterias rizosféricas para controlar la piriculariosis ResumenEl arroz es fuente de alimento para una gran parte de la población mundial, con alto promedio de consumo anual. En este cultivo las enfermedades de origen microbiano constituyen uno de los factores que inciden en la obtención de bajos rendimientos y calidad de los granos. La piriculariosis o añublo del arroz, cau...

  13. Perspectivas del uso de bacterias rizosféricas en el control de Pyricularia grisea (Cooke Sacc.) en el cultivo del arroz (Oryza sativa L.)

    OpenAIRE

    Yanelis Acebo Guerrero; Annia Hernández-Rodríguez; Narovis Rives Rodríguez; Ana Niurka Hernández-Lauzardo

    2011-01-01

    Prospect of the use of bacteria in the control Pyricularia grisea (Cooke Sacc.) on rice (Oriza sativa L.) Título corto: Bacterias rizosféricas para controlar la piriculariosis ResumenEl arroz es fuente de alimento para una gran parte de la población mundial, con alto promedio de consumo anual. En este cultivo las enfermedades de origen microbiano constituyen uno de los factores que inciden en la obtención de bajos rendimientos y calidad de los granos. La piriculariosis o añublo del arroz, cau...

  14. Identification of seed-specific promoter nap300 and its comparison with 7S promoter

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    By fusing seed-specific promoter nap300 with β-glucuronidase gene, it was found that this about 300bp DNA fragment was sufficient to direct seed-specific gene expression. The substitution mutation in both distB and proxB elements had a little effect on the expression efficiency and almost no effect on the organ-specific expression pattern. In the experiment designed to compare nap300 with 7S promoter, the result showed that tissue specificity for nap300 was higher than that for 7S, and its expression level was lower than 7S's. There was no big difference in their expression pattern, and the maximal activity stage for the two promoters was identical, which indicated they could be used simultaneously for expressing different foreign genes in seeds.

  15. Toddler's self-regulation strategies in a challenge context are nap-dependent.

    Science.gov (United States)

    Miller, Alison L; Seifer, Ronald; Crossin, Rebecca; Lebourgeois, Monique K

    2015-06-01

    Early childhood represents a time of developmental changes in both sleep and self-regulation, a construct reflecting the ability to control one's behaviour, attention and emotions when challenged. Links between sleep and self-regulation processes have been proposed, but experimental evidence with young children is lacking. In the current study, we tested the effects of acute sleep restriction (nap deprivation) on toddlers' self-regulation. Healthy children (n = 12; four males; aged 30-36 months (33.9 ± 1.7)) slept on a strict schedule (verified with actigraphy and sleep diaries) for 5 days before each of two afternoon assessments following a nap and a no-nap condition (~11-day protocol). Children were videotaped while attempting an unsolvable puzzle, and 10 mutually exclusive self-regulation strategies were later coded. On average, children lost ~90 min of sleep on the no-nap versus the nap day. Nap deprivation resulted in moderate-to-large effects on self-regulation strategies, with decreases in scepticism (d = 0.77; 7% change), negative self-appraisal (d = 0.92; 5% change) and increases in physical self-soothing (d = 0.68; 10% change), focus on the puzzle piece that would not fit (perseveration; d = 0.50; 9% change) and insistence on completing the unsolvable puzzle (d = 0.91; 10% change). Results suggest that sleep serves an important role in the way that toddlers respond to challenging events in their daily lives. After losing daytime sleep, toddlers were less able to engage effectively in a difficult task and reverted to less mature self-regulation strategies than when they were well rested. Over time, chronically missed sleep may impair young children's self-regulation abilities, resulting in risk for social-emotional, behavioural and school problems.

  16. Rapid-Eye-Movement-Sleep (REM Associated Enhancement of Working Memory Performance after a Daytime Nap.

    Directory of Open Access Journals (Sweden)

    Esther Yuet Ying Lau

    Full Text Available The main objective was to study the impact of a daytime sleep opportunity on working memory and the mechanism behind such impact. This study adopted an experimental design in a sleep research laboratory. Eighty healthy college students (Age:17-23, 36 males were randomized to either have a polysomnography-monitored daytime sleep opportunity (Nap-group, n=40 or stay awake (Wake-group, n=40 between the two assessment sessions. All participants completed a sleep diary and wore an actigraph-watch for 5 days before and one day after the assessment sessions. They completed the state-measurement of sleepiness and affect, in addition to a psychomotor vigilance test and a working memory task before and after the nap/wake sessions. The two groups did not differ in their sleep characteristics prior to and after the lab visit. The Nap-group had higher accuracy on the working memory task, fewer lapses on the psychomotor vigilance test and lower state-sleepiness than the Wake-group. Within the Nap-group, working memory accuracy was positively correlated with duration of rapid eye movement sleep (REM and total sleep time during the nap. Our findings suggested that "sleep gain" during a daytime sleep opportunity had significant positive impact on working memory performance, without affecting subsequent nighttime sleep in young adult, and such impact was associated with the duration of REM. While REM abnormality has long been noted in pathological conditions (e.g. depression, which are also presented with cognitive dysfunctions (e.g. working memory deficits, this was the first evidence showing working memory enhancement associated with REM in daytime napping in college students, who likely had habitual short sleep duration but were otherwise generally healthy.

  17. Rapid-Eye-Movement-Sleep (REM) Associated Enhancement of Working Memory Performance after a Daytime Nap.

    Science.gov (United States)

    Lau, Esther Yuet Ying; Wong, Mark Lawrence; Lau, Kristy Nga Ting; Hui, Florence Wai Ying; Tseng, Chia-huei

    2015-01-01

    The main objective was to study the impact of a daytime sleep opportunity on working memory and the mechanism behind such impact. This study adopted an experimental design in a sleep research laboratory. Eighty healthy college students (Age:17-23, 36 males) were randomized to either have a polysomnography-monitored daytime sleep opportunity (Nap-group, n=40) or stay awake (Wake-group, n=40) between the two assessment sessions. All participants completed a sleep diary and wore an actigraph-watch for 5 days before and one day after the assessment sessions. They completed the state-measurement of sleepiness and affect, in addition to a psychomotor vigilance test and a working memory task before and after the nap/wake sessions. The two groups did not differ in their sleep characteristics prior to and after the lab visit. The Nap-group had higher accuracy on the working memory task, fewer lapses on the psychomotor vigilance test and lower state-sleepiness than the Wake-group. Within the Nap-group, working memory accuracy was positively correlated with duration of rapid eye movement sleep (REM) and total sleep time during the nap. Our findings suggested that "sleep gain" during a daytime sleep opportunity had significant positive impact on working memory performance, without affecting subsequent nighttime sleep in young adult, and such impact was associated with the duration of REM. While REM abnormality has long been noted in pathological conditions (e.g. depression), which are also presented with cognitive dysfunctions (e.g. working memory deficits), this was the first evidence showing working memory enhancement associated with REM in daytime napping in college students, who likely had habitual short sleep duration but were otherwise generally healthy.

  18. KSHV encoded LANA recruits Nucleosome Assembly Protein NAP1L1 for regulating viral DNA replication and transcription

    Science.gov (United States)

    Gupta, Namrata; Thakker, Suhani; Verma, Subhash C.

    2016-09-01

    The establishment of latency is an essential for lifelong persistence and pathogenesis of Kaposi’s sarcoma-associated herpesvirus (KSHV). Latency-associated nuclear antigen (LANA) is the most abundantly expressed protein during latency and is important for viral genome replication and transcription. Replication-coupled nucleosome assembly is a major step in packaging the newly synthesized DNA into chromatin, but the mechanism of KSHV genome chromatinization post-replication is not understood. Here, we show that nucleosome assembly protein 1-like protein 1 (NAP1L1) associates with LANA. Our binding assays revealed an association of LANA with NAP1L1 in KSHV-infected cells, which binds through its amino terminal domain. Association of these proteins confirmed their localization in specific nuclear compartments of the infected cells. Chromatin immunoprecipitation assays from NAP1L1-depleted cells showed LANA-mediated recruitment of NAP1L1 at the terminal repeat (TR) region of the viral genome. Presence of NAP1L1 stimulated LANA-mediated DNA replication and persistence of a TR-containing plasmid. Depletion of NAP1L1 led to a reduced nucleosome positioning on the viral genome. Furthermore, depletion of NAP1L1 increased the transcription of viral lytic genes and overexpression decreased the promoter activities of LANA-regulated genes. These results confirmed that LANA recruitment of NAP1L1 helps in assembling nucleosome for the chromatinization of newly synthesized viral DNA.

  19. Antagonismo in vitro de Trichoderma harzianum Rifai sobre Fusarium solani (Mart. Sacc., asociado a la marchitez en maracuyá

    Directory of Open Access Journals (Sweden)

    Carol Libeth Suárez Meza

    2009-01-01

    Full Text Available Cultivos de maracuyá de la región Caribe colombiana presentan problemas de marchitez y el hongo Fusarium solani (Mart. Sacc., está asociado a esta patología. Plantas de maracuyá de la Estación Experimental (E.E Caribia de Corpoica poseen este problema y por tal razón se determinó el antagonismo in vitro de aislamientos de Trichoderma harzianum Rifai, frente a F. solani, aislado de plantas enfermas de maracuyá (Passiflora edulis. Utilizando la técnica de cultivo dual en platos Petri con Agar Sabouraud, se evaluaron competencia por nutrientes y espacio, micoparasitismo y porcentaje de inhibición del crecimiento radial (PICR, empleando un diseño estadístico factorial 2x6x1 con arreglo completamente aleatorio. Se obtuvieron tres aislamientos nativos de T. harzianum (TCN-009, TCN-010, TCN-014 de suelo de Palma de Aceite (Elaeis guineensis de la E.E Caribia, y se compararon con tres aislamientos comerciales (TCC-001, TCC-005, TCC-006. TCC-001 y TCN-014, reportaron ser más competentes por nutrientes y espacio, con el mayor radio de crecimiento de 7,50 y 7,32 cm el día 10, comparado a FSM-011 en el cual solo fue de 2,30 cm. Aunque, TCN-014 mostró micoparasitismo grado 4 con ambos aislamientos de F. solani y TCC-005 únicamente con FSM-012, el cual fue más susceptible a ser micoparasitado. En cuanto al PICR, los tratamientos con mejores porcentajes de inhibición fueron TA-9, TA-12 y TA-6 con valores de 70,56, 68,52 y 65,32% respectivamente. El aislamiento del patógeno mayormente inhibido fue FSM-011. Todos estos resultados demuestran que hubo antagonismo in vitro al utilizar los aislamientos nativos y comerciales de T. harzianum sobre F. solani.  Palabras clave: Passiflora, competencia, micoparasitismo, inhibición, antagonismo.

  20. napäeva muinasjutt : [lühijutud] / Kris, Moor, pseud.

    Index Scriptorium Estoniae

    Kris Moor, pseud.

    2007-01-01

    Sisu: Imagine an actor saying following ; algus ; korralikud tüdrukud ; Provokatsioon ; absoluutselt täiuslik ; sigaret ; best friends ; probleem ; Tere Kris ; kirjutis ; armastus ; Elluastuja ; oeh ; klishee ; happy neverending story ; tungid ja tungisaatused ; noh ; lohe ; the art of noise ; latentsus ; Lühikokkuvõte tänapäeva muinasjutust: (ilma ilukirjandusliku liialduseta)

  1. Mis on "Tänapäeva apokalüpsis"? / Kalmer Saar

    Index Scriptorium Estoniae

    Saar, Kalmer

    2006-01-01

    Francis Ford Coppola suurfilmi "Tänapäeva apokalüpsis" autoriversioon "Apocalypse Now Redux" (Ameerika Ühendriigid 2001/1979) lõpetab USA kultusfilmide festivali kinos "Sõprus". Lisa : Jaan Ruusi "Apocalypse Now Redux" selgitab autoriversiooni - director's cut - mõistet

  2. Relationship between napping during night shift work and household obligations of female nursing personnel

    Directory of Open Access Journals (Sweden)

    Silva Costa A

    2013-04-01

    Full Text Available Aline Silva-Costa,1,2 Frida Marina Fischer,1 Rosane Harter Griep,2 Lúcia Rotenberg2 1School of Public Health, University of São Paulo, São Paulo, Brazil; 2Laboratory of Health, Environment and Education, Oswaldo Cruz Institute (Fiocruz, Rio de Janeiro, Brazil Abstract: Night shift employment involves displacing sleep to the daytime. For female workers, the opportunity for daytime sleep is influenced by routine housework demands, which aggravates sleep deprivation. Allowing naps to be taken during the night shift of work is a frequent practice at some hospitals and can help reduce the effects of sleep deprivation. We hypothesize that an association between domestic work and the length of naps during night work exists for nursing professionals. To test this hypothesis, two cross-sectional studies were conducted in two different hospitals. In Study 1, female workers answered questionnaires regarding sleeping habits, professional work, and housework demands. In Study 2, data regarding napping during shifts was obtained by actigraphy, a noninvasive method of monitoring the human sleep–wake cycle. The demand for the performance of housework was measured by (i domestic work hours (total time spent performing domestic work per week, and (ii domestic workload, which considers the degree of sharing domestic tasks and the number of people living at home. The populations from the two studies were subdivided into groups, based on the duration of napping at work. Data on naps were analyzed according to domestic demands, using the Mann–Whitney and Chi-squared tests. Among the two study populations (Studies 1 and 2, those in Study 2 were older, had shorter professional weekly work hours, worked more night shifts, and dedicated more time to housework. Significant associations were only found in Study 2, where greater time napping at work was associated with both greater time spent doing housework and greater domestic workload. The known benefits of

  3. Napping in older people 'at risk' of dementia: relationships with depression, cognition, medical burden and sleep quality.

    Science.gov (United States)

    Cross, Nathan; Terpening, Zoe; Rogers, Naomi L; Duffy, Shantel L; Hickie, Ian B; Lewis, Simon J G; Naismith, Sharon L

    2015-10-01

    Sleep disturbance is prevalent in older adults, particularly so in those at a greater risk of dementia. However, so far the clinical, medical and neuropsychological correlates of daytime sleep have not been examined. The aims of this study were to investigate the characteristics and effects of napping using actigraphy in older people, particularly in those 'at risk' of dementia. The study used actigraphy and sleep diaries to measure napping habits in 133 older adults 'at risk' of dementia (mean age = 65.5 years, SD = 8.4 years), who also underwent comprehensive medical, psychiatric and neuropsychological assessment. When defined by actigraphy, napping was present in 83.5% (111/133) of participants; however, duration and timing varied significantly among subjects. Nappers had significantly greater medical burden and body mass index, and higher rates of mild cognitive impairment. Longer and more frequent naps were associated with poorer cognitive functioning, as well as higher levels of depressive symptoms, while the timing of naps was associated with poorer nocturnal sleep quality (i.e. sleep latency and wake after sleep onset). This study highlights that in older adults 'at risk' of dementia, napping is associated with underlying neurobiological changes such as depression and cognition. Napping characteristics should be more routinely monitored in older individuals to elucidate their relationship with psychological and cognitive outcomes. PMID:26096839

  4. Control of periplasmic nitrate reductase gene expression (napEDABC) from Paracoccus pantotrophus in response to oxygen and carbon substrates.

    Science.gov (United States)

    Sears, H J; Sawers, G; Berks, B C; Ferguson, S J; Richardson, D J

    2000-11-01

    The napEDABC operon of Paracoccus pantotrophus encodes a periplasmic nitrate reductase (NAP), together with electron-transfer components and proteins required for the synthesis of a fully functional enzyme. Previously, it had been shown that high NAP activity was observed when P. pantotrophus was grown aerobically on highly reduced carbon sources such as butyrate or caproate, but not when cultured on more oxidized substrates such as succinate or malate. The enzyme is not present to any extent when the organism is grown anaerobically under denitrifying conditions, regardless of the carbon source. Transcriptional analyses of the nap operon have now identified two initiation sites which were differentially regulated in response to the carbon source, with expression being maximal when cells were grown aerobically with butyrate. Analysis of a P. pantotrophus mutant (M6) deregulated for NAP activity identified a single C-->A transversion in a heptameric inverted-repeat sequence that partially overlapped the proximal promoter. Transcription analysis of this mutant revealed that expression of nap was completely derepressed under all growth conditions examined. Taken together, these findings indicate that nap transcription is negatively regulated during anaerobiosis, such that expression is restricted to aerobic growth, but only when the carbon source is highly reduced. PMID:11065376

  5. Cloning and characterization of Arabidopsis thaliana AtNAP57--a homologue of yeast pseudouridine synthase Cbf5p.

    Science.gov (United States)

    Maceluch, J; Kmieciak, M; Szweykowska-Kulińska, Z; Jarmołowski, A

    2001-01-01

    Rat Nap57 and its yeast homologue Cbf5p are pseudouridine synthases involved in rRNA biogenesis, localized in the nucleolus. These proteins, together with H/ACA class of snoRNAs compose snoRNP particles, in which snoRNA guides the synthase to direct site-specific pseudouridylation of rRNA. In this paper we present an Arabidopsis thaliana protein that is highly homologous to Cbf5p (72% identity and 85% homology) and NAP57 (67% identity and 81% homology). Moreover, the plant protein has conserved structural motifs that are characteristic features of pseudouridine synthases of the TruB class. We have named the cloned and characterized protein AtNAP57 (Arabidopsis thaliana homologue of NAP57). AtNAP57 is a 565 amino-acid protein and its calculated molecular mass is 63 kDa. The protein is encoded by a single copy gene located on chromosome 3 of the A. thaliana genome. Interestingly, the AtNAP57 gene does not contain any introns. Mutations in the human DKC1 gene encoding dyskerin (human homologue of yeast Cbf5p and rat NAP57) cause dyskeratosis congenita a rare inherited bone marrow failure syndrome characterized by abnormal skin pigmentation, nail dystrophy and mucosal leukoplakia.

  6. Integrating nap and night-time sleep into sleep patterns reveals differential links to health-relevant outcomes.

    Science.gov (United States)

    Devine, Jaime K; Wolf, Jutta M

    2016-04-01

    Both night-time sleep and nap behaviour have been linked consistently to health outcomes. Although reasons for napping are usually tied to night-time sleep, the majority of studies assess their effects independently. The current study thus aimed to examine the health relevance of patterns of sleep behaviour that take into account both night-time and daytime sleep habits. Night-time sleep, recorded during 7 days via actigraphy from 313 participants (aged 34-82 years) of the Midlife in the United States II Biomarker study, was assessed. Blood and urine specimens were assayed for noradrenaline, interleukin-6 and C-reactive protein. Participants self-reported nap behaviour, depressive symptoms, perceived chronic stress and the presence of medical symptoms and conditions. Overall, nappers (n = 208) showed elevated waist-hip ratios, C-reactive protein and interleukin-6 levels compared to non-nappers and reported more physiological symptoms and conditions (all P ≤ 0.019). Within nappers, cluster analysis revealed three patterns of sleep behaviour-infrequent nappers with good night-time sleep, frequent nappers with good night-time sleep and nappers with poor night-time sleep. Nappers with poor night-time sleep thereby exhibited elevated noradrenaline levels, depressive symptoms and perceived stress scores compared to other groups (all P ≤ 0.041). These findings support the idea that nap-health relationships are complex, in that frequency of napping and accumulation of nap sleep is not related linearly to health consequences. Assessing nap behaviour in conjunction with night-time sleep behaviour appeared crucial to elucidate further the health relevance of napping, particularly in terms of psychological health outcomes, including chronic stress and depressive symptoms. PMID:26718988

  7. Slow wave sleep during a daytime nap is necessary for protection from subsequent interference and long-term retention.

    Science.gov (United States)

    Alger, Sara E; Lau, Hiuyan; Fishbein, William

    2012-09-01

    While it is now generally accepted that sleep facilitates the processing of newly acquired declarative information, questions still remain as to the type and length of sleep necessary to best benefit declarative memories. A better understanding could lend support in one direction or another as to the much-debated role of sleep, be it passive, permissive, or active, in memory processing. The present study employed a napping paradigm and compared performance on a bimodal paired-associates task of those who obtained a 10-min nap, containing only Stages 1 and 2 sleep, to those whose nap contained slow-wave sleep (SWS) and rapid eye movement (REM) sleep (60-min nap), as well as to subjects who remained awake. Measurements were obtained for baseline performance at training, after a sleep/no sleep interval for short-term retention, after a subsequent stimulus-related interference task, and again after a weeklong retention period. While all groups learned the information similarly, both nap groups performed better than the Wake group when examining short-term retention, approximately 1.5h after training (10-min p=.052, 60-min p=.002). However, performance benefits seen in the 10-min nap group proved to be temporary. Performance after a stimulus-related interference task revealed significantly better memory retention in the 60-min nap group, with interference disrupting the memory trace far less than both the Wake and 10-min nap groups (pconsolidation of learned bimodal paired-associates, supported by theories such as the Standard Theory of Consolidation as well as the Synaptic Homeostasis Hypothesis.

  8. Slow wave sleep during a daytime nap is necessary for protection from subsequent interference and long-term retention.

    Science.gov (United States)

    Alger, Sara E; Lau, Hiuyan; Fishbein, William

    2012-09-01

    While it is now generally accepted that sleep facilitates the processing of newly acquired declarative information, questions still remain as to the type and length of sleep necessary to best benefit declarative memories. A better understanding could lend support in one direction or another as to the much-debated role of sleep, be it passive, permissive, or active, in memory processing. The present study employed a napping paradigm and compared performance on a bimodal paired-associates task of those who obtained a 10-min nap, containing only Stages 1 and 2 sleep, to those whose nap contained slow-wave sleep (SWS) and rapid eye movement (REM) sleep (60-min nap), as well as to subjects who remained awake. Measurements were obtained for baseline performance at training, after a sleep/no sleep interval for short-term retention, after a subsequent stimulus-related interference task, and again after a weeklong retention period. While all groups learned the information similarly, both nap groups performed better than the Wake group when examining short-term retention, approximately 1.5h after training (10-min p=.052, 60-min p=.002). However, performance benefits seen in the 10-min nap group proved to be temporary. Performance after a stimulus-related interference task revealed significantly better memory retention in the 60-min nap group, with interference disrupting the memory trace far less than both the Wake and 10-min nap groups (pconsolidation of learned bimodal paired-associates, supported by theories such as the Standard Theory of Consolidation as well as the Synaptic Homeostasis Hypothesis. PMID:22732649

  9. Erotic subset for the Nencki Affective Picture System (NAPS ERO): cross-sexual comparison study.

    Science.gov (United States)

    Wierzba, Małgorzata; Riegel, Monika; Pucz, Anna; Leśniewska, Zuzanna; Dragan, Wojciech Ł; Gola, Mateusz; Jednoróg, Katarzyna; Marchewka, Artur

    2015-01-01

    Research on the processing of sexual stimuli has proved that such material has high priority in human cognition. Yet, although sex differences in response to sexual stimuli were extensively discussed in the literature, sexual orientation was given relatively little consideration, and material suitable for relevant research is difficult to come by. With this in mind, we present a collection of 200 erotic images, accompanied by their self-report ratings of emotional valence and arousal by homo- and heterosexual males and females (n = 80, divided into four equal-sized subsamples). The collection complements the Nencki Affective Picture System (NAPS) and is intended to be used as stimulus material in experimental research. The erotic images are divided into five categories, depending on their content: opposite-sex couple (50), male couple (50), female couple (50), male (25) and female (25). Additional 100 control images from the NAPS depicting people in a non-erotic context were also used in the study. We showed that recipient sex and sexual orientation strongly influenced the evaluation of erotic content. Thus, comparisons of valence and arousal ratings in different subject groups will help researchers select stimuli set for the purpose of various experimental designs. To facilitate the use of the dataset, we provide an on-line tool, which allows the user to browse the images interactively and select proper stimuli on the basis of several parameters. The NAPS ERO image collection together with the data are available to the scientific community for non-commercial use at http://naps.nencki.gov.pl. PMID:26441715

  10. Illustratsioon eesti tänapäevases täiskasvanute ilukirjanduses / Martin Tõnts

    Index Scriptorium Estoniae

    Tõnts, Martin

    2010-01-01

    Uuritakse illustratsiooni funktsioone tänapäevases eesti ilukirjanduses, kas ja kuidas on need seotud tekstiga, on sellest inspireeritud või ei, kuivõrd annavad edasi tekstis peituvat või iseseisvat informatsiooni või on pelgalt kaunistavad, nagu peamiselt luulekogudes esinevad illustratsioonid. Praktilise tööna on Birk Rohelennu "Alexander ja Belle" raamatu kujundus, küljendus ja illustratsioonid

  11. The impact of napping on memory for future-relevant stimuli: Prioritization among multiple salience cues.

    Science.gov (United States)

    Bennion, Kelly A; Payne, Jessica D; Kensinger, Elizabeth A

    2016-06-01

    Prior research has demonstrated that sleep enhances memory for future-relevant information, including memory for information that is salient due to emotion, reward, or knowledge of a later memory test. Although sleep has been shown to prioritize information with any of these characteristics, the present study investigates the novel question of how sleep prioritizes information when multiple salience cues exist. Participants encoded scenes that were future-relevant based on emotion (emotional vs. neutral), reward (rewarded vs. unrewarded), and instructed learning (intentionally vs. incidentally encoded), preceding a delay consisting of a nap, an equivalent time period spent awake, or a nap followed by wakefulness (to control for effects of interference). Recognition testing revealed that when multiple dimensions of future relevance co-occur, sleep prioritizes top-down, goal-directed cues (instructed learning, and to a lesser degree, reward) over bottom-up, stimulus-driven characteristics (emotion). Further, results showed that these factors interact; the effect of a nap on intentionally encoded information was especially strong for neutral (relative to emotional) information, suggesting that once one cue for future relevance is present, there are diminishing returns with additional cues. Sleep may binarize information based on whether it is future-relevant or not, preferentially consolidating memory for the former category. Potential neural mechanisms underlying these selective effects and the implications of this research for educational and vocational domains are discussed. (PsycINFO Database Record PMID:27214500

  12. Variación patogénica y fuentes de resistencia a Colletotrichum lindemuthianum Sacc & magn Scrib., patógeno de la antracnosis del frijol, en Colombia Variación patogénica y fuentes de resistencia a Colletotrichum lindemuthianum (Sacc & Magn Scrib., patógeno de la antracnosis del fríjol, en Colombia

    Directory of Open Access Journals (Sweden)

    Cobo S. Felipe

    1987-03-01

    Full Text Available Pathogenic variation studies with colombian isolates of Colletotrichum lindemuthianum (Sacc & Magn Scrib., the anthracnose bean pathogen, were conducted under laboratory and greenhouse conditions at CIAT, Colombia. In addition, bean germplam with cormercial grain color was evaluated with the objective of identifying resistant varieties and sources of resistance to the existing variation. To this purpose, 17 isolates of C. lindemuthianum collected at the principal Colombian bean zones, were inoculated on 21 American and European differential bean varieties.En los laboratorios e invernaderos del programa de fitopatología de fríjol del CIAT, se estudió la variación patogénica de aislamientos colombianos de Colletotrichum lindemuthianum (Sacc& Magn Scrib. También se evaluó germoplasma de frijol con grano de color comercial con el objetivo de identificar líneas resistentes y fuentes de resistencia a la variación existente. Para este fin, 17 aislamientos de C.lindemuthianum, colectados en las principales zonas frijoleras colombianas se inocularon sobre 21 variedades diferenciales.

  13. Development of decontamination technique for radioactive Cs in soil using composite material of Na-P1 type zeolite and magnetite

    International Nuclear Information System (INIS)

    Na-P1 type zeolite is a porous material with its pore opening size similar to the diameter of Cs+, and has considerably high adsorption selectivity for Cs+. In Fukushima, we conducted experiments to remove radioactive Cs from some soils, by using magnetized Na-P1, a composite of magnetite and Na-P1. By mixing soil with the magnetized Na-P1, with the mass ratio of 10:1, in ammonium oxalate solution for 10 min, more than 80% of radioactive Cs was removed from soil. Important factors for the successful removal of radioactive Cs from soils were preparation of soil composite with no separation of magnetite and Na-P1 during the mixing, optimization of the structure of magnetic separator which separate soil and magnetized Na-P1, and the selection of solution in the mixing procedure. (author)

  14. Work schedule and self-reported hypertension - the potential beneficial role of on-shift naps for night workers.

    Science.gov (United States)

    Rotenberg, Lúcia; Silva-Costa, Aline; Vasconcellos-Silva, Paulo Roberto; Griep, Rosane Härter

    2016-01-01

    Data on the association between shift work and hypertension are controversial. Sleep restriction is hypothesized to be involved in this relationship. Since on-shift nap can partly compensate for sleep deprivation among night workers, this investigation is aimed at (i) comparing the prevalence of hypertension among workers considering both current and former night work, (ii) testing the association between on-shift naps and hypertension among night workers, and (iii) analyzing the influence of sleep complaints in the association between on-shift nap and hypertension. Nap was defined as a sleep episode with duration shorter than the average nighttime sleep. A cross-sectional study was performed at the 18 largest public hospitals in Rio de Janeiro, Brazil, in 2010-2011 (N = 2588 female registered nurses). Nurses were informally allowed to nap for up to three consecutive hours during working nights. Workers completed a multidimensional questionnaire including self-reported information on physician diagnosis of hypertension, napping, and sleep complaints (insomnia, diurnal sleepiness, and non-satisfactory sleep). Epidemiological and statistical treatment of data included binomial logistic regression and interaction tests. Higher chances of hypertension were observed for both current and former night workers compared with workers with no previous experience in night work, i.e. exclusive day workers (OR = 1.68; CI95% 1.22-2.33 and OR = 1.40; CI95% 1.01-1.96, respectively) after adjustment for age, race/ethnicity, physical activity, smoking, alcohol consumption, insomnia, weekly work hours, and BMI. Compared with exclusive day workers, both non-nappers and nappers were at a higher likelihood of reporting hypertension (OR = 1.93 CI95% 1.35-2.79 and OR = 1.41 CI95% 1.08-2.20, respectively). An interaction was observed between napping behavior and insomnia (p = 0.037). In the whole sample of night workers, the lower OR for nappers was confirmed when they were directly

  15. REM-Enriched Naps Are Associated with Memory Consolidation for Sad Stories and Enhance Mood-Related Reactivity

    Directory of Open Access Journals (Sweden)

    Médhi Gilson

    2015-12-01

    Full Text Available Emerging evidence suggests that emotion and affect modulate the relation between sleep and cognition. In the present study, we investigated the role of rapid-eye movement (REM sleep in mood regulation and memory consolidation for sad stories. In a counterbalanced design, participants (n = 24 listened to either a neutral or a sad story during two sessions, spaced one week apart. After listening to the story, half of the participants had a short (45 min morning nap. The other half had a long (90 min morning nap, richer in REM and N2 sleep. Story recall, mood evolution and changes in emotional response to the re-exposure to the story were assessed after the nap. Although recall performance was similar for sad and neutral stories irrespective of nap duration, sleep measures were correlated with recall performance in the sad story condition only. After the long nap, REM sleep density positively correlated with retrieval performance, while re-exposure to the sad story led to diminished mood and increased skin conductance levels. Our results suggest that REM sleep may not only be associated with the consolidation of intrinsically sad material, but also enhances mood reactivity, at least on the short term.

  16. NAP (davunetide) protects primary hippocampus culture by modulating expression profile of antioxidant genes during limiting oxygen conditions.

    Science.gov (United States)

    Arya, A; Meena, R; Sethy, N K; Das, M; Sharma, M; Bhargava, K

    2015-04-01

    Hypoxia is a well-known threat to neuronal cells and triggers the pathophysiological syndromes in extreme environments such as high altitudes and traumatic conditions such as stroke. Among several prophylactic molecules proven suitable for ameliorating free radical damage, NAP (an octapeptide with initial amino acids: asparagine/N, alanine/A, and proline/P) can be considered superlative, primarily due to its high permeability into brain through blood-brain barrier and observed activity at femtomolar concentrations. Several mechanisms of action of NAP have been hypothesized for its protective role during hypoxia, yet any distinct mechanism is unknown. Oxidative stress is advocated as the leading event in hypoxia; we, therefore, investigated the regulation of key antioxidant genes to understand the regulatory role of NAP in providing neuroprotection. Primary neuronal culture of rat was subjected to cellular hypoxia by limiting the oxygen concentration to 0.5% for 72 h and observing the prophylactic efficacies of 15fM NAP by conventional cell death assays using flow cytometry. We performed real-time quantitative polymerase chain reaction to comprehend the regulatory mechanism. Further, we validated the significantly regulated candidates by enzyme assays and immunoblotting. In the present study, we report that NAP regulates a major clad of cellular antioxidants and there is an involvement of more than one route of action in neuroprotection during hypoxia. PMID:25727410

  17. Nap environment control considering respiration rate and music tempo by using sensor agent robot

    Science.gov (United States)

    Nakaso, Sayaka; Mita, Akira

    2015-03-01

    We propose a system that controls a nap environment considering respiration rates and music tempo by using a sensor agent robot. The proposed system consists of two sub-systems. The first sub-system measures respiration rates using optical flow. We conducted preparatory experiments to verify the accuracy of this sub-system. The experimental results showed that this sub-system can measure the respiration rates accurately despite several positional relationships. It was also shown that the accuracy could be affected by clothes, movements and light. The second sub-system we constructed was the music play sub-system that chooses music with the certain tempo corresponding to the respiration rates measured by the first sub-system. We conducted verification experiments to verify the effectiveness of this music play sub-system. The experimental results showed the effectiveness of varying music tempo based on the respiration rates in taking a nap. We also demonstrated this system in a real environment; a subject entered into the room being followed by ebioNα. When the subject was considered sleeping, ebioNα started measuring respiration rates, controlling music based on the respiration rates. As a result, we showed that this system could be realized. As a next step, we would like to improve this system to a nap environment control system to be used in offices. To realize this, we need to update the first sub-system measuring respiration rates by removing disturbances. We also need to upgrade music play sub-system considering the numbers of tunes, the kinds of music and time to change music.

  18. Cloning, expression and anticoagulant activities of anticoagulant peptide AcaNAP8 from Ancylostoma caninum%犬钩虫抗凝肽AcaNAP8的原核表达及其抗凝活性

    Institute of Scientific and Technical Information of China (English)

    殷环; 邓莉; 王会兰; 吴亚敏; 彭礼飞

    2010-01-01

    目的 在大肠杆菌中重组表达犬钩虫抗凝肽AcaNAP8基因,并检测表达产物抗凝活性.方法 设计引物,将AcaNAP8成熟肽编码序列克隆、连接到原核表达载体pET32a,构建重组表达质粒;成功构建的重组表达质粒转化到大肠杆菌BL21(DE3)中用IPTG诱导表达,SDS-PAGE分析表达情况;诱导表达的重组蛋白用Ni亲和层析进行纯化;用凝血酶原时问(PT)和活化的部分凝血活酶时间(aPTTr)检测重组产物体外抗凝活性.结果 成功构建了pET32a/AcaNAP8原核表达重组质粒,在大肠杆菌中成功表达并获得了重组AcaNAP8,表达产物能明显延长PT及aPTT.结论 在大肠杆菌中成功表达了AcaNAP8融合蛋白,表达产物具有显著抗凝活性.该实验为进一步探讨AcaNAP8的作用机制及应用奠定了基础.

  19. Preparation of composite materials of Na-P1 type zeolite and magnetite for Cs decontamination in soil

    International Nuclear Information System (INIS)

    The reaction time and the concentration of NaOH solution were studied for the preparation of Na-P1 type zeolite using fly-ach. Addition of NaAlO2 is effective for the improvement of cation exchange capacity (CEC) value. A new composite material consisting of the Na-P1 type zeolite and magnetite was synthesized from the waste fly-ash of thermal power stations and iron chlorides for the decontamination of radioactive 134Cs and 137Cs. The magnetic collection was possible using this composite material after Cs+ ion adsorption. The existence of nanosized magnetites in the polycrystalline zeolite (several micrometers) was confirmed by TEM observations. Decontamination test of the radioactive Cs+ ion using the magnetic Na-P1 type zeolite and the soil was succeeded. (author)

  20. Histone density is maintained during transcription mediated by the chromatin remodeler RSC and histone chaperone NAP1 in vitro.

    Science.gov (United States)

    Kuryan, Benjamin G; Kim, Jessica; Tran, Nancy Nga H; Lombardo, Sarah R; Venkatesh, Swaminathan; Workman, Jerry L; Carey, Michael

    2012-02-01

    ATPases and histone chaperones facilitate RNA polymerase II (pol II) elongation on chromatin. In vivo, the coordinated action of these enzymes is necessary to permit pol II passage through a nucleosome while restoring histone density afterward. We have developed a biochemical system recapitulating this basic process. Transcription through a nucleosome in vitro requires the ATPase remodels structure of chromatin (RSC) and the histone chaperone nucleosome assembly protein 1 (NAP1). In the presence of NAP1, RSC generates a hexasome. Despite the propensity of RSC to evict histones, NAP1 reprograms the reaction such that the hexasome is retained on the template during multiple rounds of transcription. This work has implications toward understanding the mechanism of pol II elongation on chromatin.

  1. Stress Physiology and Virulence Characterization of Phomopsis asparagi (Sacc.) Bub6k isolated from Asparagus in Jiangxi Province of China

    Institute of Scientific and Technical Information of China (English)

    Yueping ZHANG; Guangyu CHEN; Shaochun LUO; Huaxiang QU; Yongping TANG; Qixin XIE; Jinsong ZHOU

    2012-01-01

    Abstract Fungal pathogen of asparagus stem blight was isolated. No significant ge- netic difference was detected among the three strains with 492 bp long ITS1-5.8S- ITS2 sequence. It was then identified through colony growth, conidia morphology, and molecular characterization. The physiological response to oxidation and osmosis stress, and virulence to Asparagus officinalis L. were analyzed. The results showed that the pathogen causing asparagus stem blight for A. officinalis L. in Jiangxi Province is Phomopsis asparagri (Sacc.) Bubok. Under pure culture conditions, the conidia were oval-shaped (a-type), with colorless single spore and single nucleus, containing 0-2 oil balls. Its vegetative growth rate was higher when cultured on 0.2 x potato dextrose agar (0.2 x PDA) medium than that on oatmeal agar (OA) medium. However, the pycnidia appeared earlier on OA medium than on 0.2 earlier PDA medium. The vegetative growth rate was depressed under oxidation (H202) or osmo- sis (NaCI) stress conditions, and totally inhibited under 7 mmol/L H202 or 2.4 mol/L NaCI. All the strains caused typical pathogenic symptoms to Asparagus officinalis L. at 7 days-post-inoculation (dpi) with conidia.

  2. Napping during the night shift and recovery after work among hospital nurses

    Directory of Open Access Journals (Sweden)

    Thaís Aparecida de Castro Palermo

    2015-02-01

    Full Text Available OBJECTIVE: To analyze the association between the length of napping during the night shift and the recovery after work among nurses.METHOD: Cross-sectional epidemiological study involving 1940 nurses from 18 public hospitals in the City of Rio de Janeiro. A multidimensional and self-applied questionnaire was used with information about health, sociodemographic and occupational characteristics, health-related behaviors and housework. Multiple logistic regression was applied to identify the association, adjusted for confounding variables.RESULTS: The gross analyses showed 44%, 127% and 66% higher chances of a high level of recovery after work for nurses who sleep up to two hours, between 2.1 and 3 hours and 3.1 hours or more, respectively, when compared to the nurses who do not sleep. After adjusting for confounding variables, the association only continues significant for the group that sleeps 2.1 to 3 hours during the night shift (OR=1.79; 95%CI=1.33-2.41.CONCLUSION: The association between the length of napping and the high level of recovery after work, confirmed in the present results, can be included in the studies that aim to support more appropriate policies aimed at improving the workers' work, life and health conditions, not only in nursing, but night-shift workers in general.

  3. Napping during the night shift and recovery after work among hospital nurses1

    Science.gov (United States)

    Palermo, Thaís Aparecida de Castro; Rotenberg, Lúcia; Zeitoune, Regina Célia Gollner; Silva-Costa, Aline; Souto, Ester Paiva; Griep, Rosane Härter

    2015-01-01

    OBJECTIVE: To analyze the association between the length of napping during the night shift and the recovery after work among nurses. METHOD: Cross-sectional epidemiological study involving 1940 nurses from 18 public hospitals in the City of Rio de Janeiro. A multidimensional and self-applied questionnaire was used with information about health, sociodemographic and occupational characteristics, health-related behaviors and housework. Multiple logistic regression was applied to identify the association, adjusted for confounding variables. RESULTS: The gross analyses showed 44%, 127% and 66% higher chances of a high level of recovery after work for nurses who sleep up to two hours, between 2.1 and 3 hours and 3.1 hours or more, respectively, when compared to the nurses who do not sleep. After adjusting for confounding variables, the association only continues significant for the group that sleeps 2.1 to 3 hours during the night shift (OR=1.79; 95%CI=1.33-2.41). CONCLUSION: The association between the length of napping and the high level of recovery after work, confirmed in the present results, can be included in the studies that aim to support more appropriate policies aimed at improving the workers' work, life and health conditions, not only in nursing, but night-shift workers in general. PMID:25806639

  4. Synthesis and characterization of zeolite NaP using kaolin waste as a source of silicon and aluminum

    Energy Technology Data Exchange (ETDEWEB)

    Hildebrando, Edemarino Araujo, E-mail: edemarino@ufpa.br [Universidae Federal do Para (UFPA), Maraba, PA (Brazil). Fac. de Engenharia de Materias. Lab. de Materiais Ceramicos; Andrade, Christiano Gianesi Bastos; Valenzuela-Diaz, Francisco Rolando [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Dept. de Metalurgia e Engenharia de Materiais; Rocha Junior, Carlos Augusto Ferreira da; Neves, Roberto de Freitas [Universidae Federal do Para (UFPA), Maraba, PA (Brazil). Int. de Tecnologia. Fac. de Engenharia Quimica; Angelica, Romulo Simoes [Universidae Federal do Para (UFPA), Maraba, PA (Brazil). Inst. de Geociencias. Fac. de Geologia

    2014-08-15

    The synthesis of zeolite NaP using kaolin waste, from the Amazon region, as a predominant source of silicon and aluminum has been studied. The zeolitisation process occurred in hydrothermal conditions using static autoclaving and the effects of time, temperature, and the Si/Al ratio were investigated. The starting material and the phases formed as reaction products were characterized by XRD, SEM and FTIR. The results showed that pure zeolite NaP is hydrothermally synthesized, at 100 °C for 20 hours, using meta kaolin waste material in alkaline medium in presence of additional silica. The XRD and SEM analyses indicate that the synthesized zeolite presents good crystallinity. (author)

  5. Synthesis and characterization of zeolite NaP using kaolin waste as a source of silicon and aluminum

    International Nuclear Information System (INIS)

    The synthesis of zeolite NaP using kaolin waste, from the Amazon region, as a predominant source of silicon and aluminum has been studied. The zeolitisation process occurred in hydrothermal conditions using static autoclaving and the effects of time, temperature, and the Si/Al ratio were investigated. The starting material and the phases formed as reaction products were characterized by XRD, SEM and FTIR. The results showed that pure zeolite NaP is hydrothermally synthesized, at 100 °C for 20 hours, using meta kaolin waste material in alkaline medium in presence of additional silica. The XRD and SEM analyses indicate that the synthesized zeolite presents good crystallinity. (author)

  6. Characterization of Clostridium difficile Strains in British Columbia, Canada: A Shift from NAP1 Majority (2008) to Novel Strain Types (2013) in One Region

    Science.gov (United States)

    Jassem, Agatha N.; Prystajecky, Natalie; Marra, Fawziah; Kibsey, Pamela; Tan, Kennard; Umlandt, Patricia; Janz, Loretta; Champagne, Sylvie; Gamage, Bruce; Golding, George R.; Mulvey, Michael R.; Henry, Bonnie

    2016-01-01

    Background. Clostridium difficile is a major cause of gastrointestinal illness. Epidemic NAP1 strains contain toxins A and B, a deletion in repressor tcdC, and a binary toxin. Objectives. To determine the molecular epidemiology of C. difficile in British Columbia and compare between two time points in one region. Methods. C. difficile isolates from hospital and community laboratories (2008) and one Island Health hospital laboratory (2013) were characterized by pulsed-field gel electrophoresis, PCR-ribotyping, toxin possession, tcdC genotype, and antimicrobial susceptibility. Results. In 2008, 42.7% of isolates had NAP1 designation. Hospital-collected isolates were associated with older patients and more NAP1 types. Unlike other isolates, most NAP1 isolates possessed binary toxin and a 19 bp loss in tcdC. All isolates were susceptible to metronidazole and vancomycin. A 2013 follow-up revealed a 28.9% decrease in NAP1 isolates and 20.0% increase in isolates without NAP designation in one region. Then, community-associated cases were seen in younger patients, while NAP types were evenly distributed. Isolates without NAP designation did not cluster with a PFGE pattern or ribotype. Conclusions. Evaluation of C. difficile infections within British Columbia revealed demographic associations, epidemiological shifts, and characteristics of strain types. Continuous surveillance of C. difficile will enable detection of emerging strains. PMID:27366181

  7. 十二指肠钩虫抗凝蛋白AduNAP7的原核表达、纯化及抗凝活性鉴定%Prokaryotic expression,purification and anticoagulant activities analysis of AduNAP7,an anticoagulant protein from Ancylostoma duodenale

    Institute of Scientific and Technical Information of China (English)

    彭礼飞; 邓莉; 杨陈; 胡晶晶; 甘伟琼; 吴亚敏; 付汉维

    2007-01-01

    目的 在大肠杆菌中表达十二指肠钩虫抗凝蛋白AduNAP7并鉴定抗凝活性.方法 运用RT-PCR扩增十二指肠钩虫抗凝蛋白AduNAP7成熟蛋白及其组成肽段AduNAP7A、AduNAP7B的编码序列;将编码序列克隆、连接到原核表达载体pET32a及pICET32,构建重组表达质粒;成功构建的重组表达质粒转化到大肠杆菌BL21(DE3)中,用IPTG诱导表达;用镍亲和层析一步纯化融合有硫氧还蛋白(Trx)的目的蛋白;先后用几丁质亲和层析及镍亲和层析两个步骤纯化自切割后带6×his-tag的目的蛋白;用凝血酶原时间(PT)和活化部分凝血活酶时间(aPTT)检测纯化表达产物的体外抗凝活性.结果 获得AduNAP7、AduNAP7A及AduNAP7B的编码序列并成功构建了原核表达重组质粒;AduNAP7、AduNAP7A及AduNAP7B均在大肠中得到了高效可溶表达,纯化产物具有一定抗凝活性,它们延长aPTT比延长PT更有效.AduNAP7B的抗凝活性显著强于AduNAP7及AduNAP7A.结论 AduNAP7具有较强抗凝活性,但显著弱于AcAP5、AcaNAP7及AcAPc2.AduNAP7的抗凝效应可能利于钩虫在人体内的吸血寄生生活,其抗凝作用机制有待进一步研究.

  8. NAP1-Assisted Nucleosome Assembly on DNA Measured in Real Time by Single-Molecule Magnetic Tweezers

    NARCIS (Netherlands)

    Vlijm, R.; Smitshuijzen, J.S.J.; Lusser, A.; Dekker, C.

    2012-01-01

    While many proteins are involved in the assembly and (re)positioning of nucleosomes, the dynamics of protein-assisted nucleosome formation are not well understood. We study NAP1 (nucleosome assembly protein 1) assisted nucleosome formation at the single-molecule level using magnetic tweezers. This m

  9. Corpus cavernosum electromyography during morning naps in healthy volunteers: further evidence that corpus cavernosum potentials reflect sympathetically mediated activity.

    NARCIS (Netherlands)

    Jiang, X.; Meuleman, E.J.H.; Wijkstra, H.; Wagner, G.

    2005-01-01

    PURPOSE: We assessed the practicability of corpus cavernosum (CC) electromyography (EMG) in volunteers during morning naps in the laboratory and further validated this method. MATERIALS AND METHODS: A total of 11 healthy volunteers with a mean age of 23.8 years (range 19 to 31) were included. CC-EMG

  10. Optimizing sleep/wake schedules in space: Sleep during chronic nocturnal sleep restriction with and without diurnal naps

    Science.gov (United States)

    Mollicone, Daniel J.; Van Dongen, Hans P. A.; Dinges, David F.

    2007-02-01

    Effective sleep/wake schedules for space operations must balance severe time constraints with allocating sufficient time for sleep in order to sustain high levels of neurobehavioral performance. Developing such schedules requires knowledge about the relationship between scheduled "time in bed" (TIB) and actual physiological sleep obtained. A ground-based laboratory study in N=93 healthy adult subjects was conducted to investigate physiological sleep obtained in a range of restricted sleep schedules. Eighteen different conditions with restricted nocturnal anchor sleep, with and without diurnal naps, were examined in a response surface mapping paradigm. Sleep efficiency was found to be a function of total TIB per 24 h regardless of how the sleep was divided among nocturnal anchor sleep and diurnal nap sleep periods. The amounts of sleep stages 1+2 and REM showed more complex relationships with the durations of the anchor and nap sleep periods, while slow-wave sleep was essentially preserved among the different conditions of the experiment. The results of the study indicated that when sleep was chronically restricted, sleep duration was largely unaffected by whether the sleep was placed nocturnally or split between nocturnal anchor sleep periods and daytime naps. Having thus assessed that split-sleep schedules are feasible in terms of obtaining physiological sleep, further research will reveal whether these schedules and the associated variations in the distribution of sleep stages may be advantageous in mitigating neurobehavioral performance impairment in the face of limited time for sleep.

  11. Resonances in the sup 22 Na(p,. gamma. ) sup 23 Mg reaction

    Energy Technology Data Exchange (ETDEWEB)

    Seuthe, S.; Rolfs, C.; Schroeder, U.; Schulte, W.H.; Somorjai, E.; Trautvetter, H.P.; Waanders, F.B. (Muenster Univ. (Germany, F.R.). Inst. fuer Kernphysik); Kavanagh, R.W. (California Inst. of Tech., Pasadena (USA)); Ravn, H. (European Organization for Nuclear Research, Geneva (Switzerland)); Arnould, M.; Paulus, G. (Universite Libre de Bruxelles (Belgium). Inst. d' Astronomie et d' Astrophysique)

    1990-08-06

    The reaction {sup 22}Na(p, {gamma}){sup 23}Mg has been investigated in the energy range E{sub p}=0.17-1.2.9 MeV using a {sup 22}Na implanted target, a D{sub 2}O threshold detector, and NaI(Tl) and Ge detectors. Resonances in this reaction have been observed for the first time at E{sub p}=290, 457, 503, 613, 740 and 796 keV. The strengths of these resonances, and upper limits on the strengths for expected resonances in the energy range covered, are given. The stellar reaction rates deduced from the present work are about one order of magnitude than previous theoretical estimates; they are however significantly higher than the upper limits from one previous measurement. Some astrophysical consequences are discussed. (orig.).

  12. Napping-Ultra Flash Profile as a Tool for Category Identification and Subsequent Model System Formulation of Caramel Corn Products.

    Science.gov (United States)

    Mayhew, Emily; Schmidt, Shelly; Lee, Soo-Yeun

    2016-07-01

    In a novel approach to formulation, the flash descriptive profiling technique Napping-Ultra Flash Profile (Napping-UFP) was used to characterize a wide range of commercial caramel corn products. The objectives were to identify product categories, develop model systems based on product categories, and correlate analytical parameters with sensory terms generated through the Napping-UFP exercise. In one 2 h session, 12 panelists participated in 4 Napping-UFP exercises, describing and grouping, on a 43×56 cm paper sheet, 12 commercial caramel corn samples by degree of similarity, globally and in terms of aroma-by-mouth, texture, and taste. The coordinates of each sample's placement on the paper sheet and descriptive terms generated by the panelists were used to conduct Multiple Factor Analysis (MFA) and hierarchical clustering of the samples. Strong trends in the clustering of samples across the 4 Napping-UFP exercises resulted in the determination of 3 overarching types of commercial caramel corn: "small-scale dark" (typified by burnt, rich caramel corn), "large-scale light" (typified by light and buttery caramel corn), and "large-scale dark" (typified by sweet and molasses-like caramel corn). Representative samples that best exemplified the properties of each category were used as guides in the formulation of 3 model systems that represent the spread of commercial caramel corn products. Analytical testing of the commercial products, including aw measurement, moisture content determination, and thermal characterization via differential scanning calorimetry, were conducted and results related to sensory descriptors using Spearman's correlation. PMID:27249670

  13. Solutions Network Formulation Report. Reducing Light Pollution in U.S. Coastal Regions Using the High Sensitivity Cameras on the SAC-C and Aquarius/SAC-D Satellites

    Science.gov (United States)

    Andrews, Jane C.; Knowlton, Kelly

    2007-01-01

    Light pollution has significant adverse biological effects on humans, animals, and plants and has resulted in the loss of our ability to view the stars and planets of the universe. Over half of the U.S. population resides in coastal regions where it is no longer possible to see the stars and planets in the night sky. Forty percent of the entire U.S. population is never exposed to conditions dark enough for their eyes to convert to night vision capabilities. In coastal regions, urban lights shine far out to sea where they are augmented by the output from fishing boat, cruise ship and oil platform floodlights. The proposed candidate solution suggests using HSCs (high sensitivity cameras) onboard the SAC-C and Aquarius/SAC-D satellites to quantitatively evaluate light pollution at high spatial resolution. New products modeled after pre-existing, radiance-calibrated, global nighttime lights products would be integrated into a modified Garstang model where elevation, mountain screening, Rayleigh scattering, Mie scattering by aerosols, and atmospheric extinction along light paths and curvature of the Earth would be taken into account. Because the spatial resolution of the HSCs on SAC-C and the future Aquarius/SAC-D missions is greater than that provided by the DMSP (Defense Meteorological Satellite Program) OLS (Operational Linescan System) or VIIRS (Visible/Infrared Imager/Radiometer Suite), it may be possible to obtain more precise light intensity data for analytical DSSs and the subsequent reduction in coastal light pollution.

  14. The histone chaperones Nap1 and Vps75 bind histones H3 and H4 in a tetrameric conformation.

    Science.gov (United States)

    Bowman, Andrew; Ward, Richard; Wiechens, Nicola; Singh, Vijender; El-Mkami, Hassane; Norman, David George; Owen-Hughes, Tom

    2011-02-18

    Histone chaperones physically interact with histones to direct proper assembly and disassembly of nucleosomes regulating diverse nuclear processes such as DNA replication, promoter remodeling, transcription elongation, DNA damage, and histone variant exchange. Currently, the best-characterized chaperone-histone interaction is that between the ubiquitous chaperone Asf1 and a dimer of H3 and H4. Nucleosome assembly proteins (Nap proteins) represent a distinct class of histone chaperone. Using pulsed electron double resonance (PELDOR) measurements and protein crosslinking, we show that two members of this class, Nap1 and Vps75, bind histones in the tetrameric conformation also observed when they are sequestered within the nucleosome. Furthermore, H3 and H4 trapped in their tetrameric state can be used as substrates in nucleosome assembly and chaperone-mediated lysine acetylation. This alternate mode of histone interaction provides a potential means of maintaining the integrity of the histone tetramer during cycles of nucleosome reassembly.

  15. REM-Enriched Naps Are Associated with Memory Consolidation for Sad Stories and Enhance Mood-Related Reactivity

    OpenAIRE

    Médhi Gilson; Gaétane Deliens; Rachel Leproult; Alice Bodart; Antoine Nonclercq; Rudy Ercek; Philippe Peigneux

    2015-01-01

    Emerging evidence suggests that emotion and affect modulate the relation between sleep and cognition. In the present study, we investigated the role of rapid-eye movement (REM) sleep in mood regulation and memory consolidation for sad stories. In a counterbalanced design, participants (n = 24) listened to either a neutral or a sad story during two sessions, spaced one week apart. After listening to the story, half of the participants had a short (45 min) morning nap. The other half had a long...

  16. Synthesis of Zeolites Na-P1 from South African Coal Fly Ash: Effect of Impeller Design and Agitation

    Directory of Open Access Journals (Sweden)

    Leslie Petrik

    2013-05-01

    Full Text Available South African fly ash has been shown to be a useful feedstock for the synthesis of some zeolites. The present study focuses on the effect of impeller design and agitation rates on the synthesis of zeolite Na-P1 which are critical to the commercialization of this product. The effects of three impeller designs (4-flat blade, Anchor and Archimedes screw impellers and three agitation speeds (150, 200 and 300 rpm were investigated using a modified previously reported synthesis conditions; 48 hours of ageing at 47 °C and static hydrothermal treatment at 140 °C for 48 hours. The experimental results demonstrated that the phase purity of zeolite Na-P1 was strongly affected by the agitation rate and the type of impeller used during the ageing step of the synthesis process. Although zeolite Na-P1 was synthesized with a space time yield (STY of 15 ± 0.4 kg d−1m−3and a product yield of 0.98±0.05 g zeolites/g fly ash for each impeller at different agitation speeds, zeolite formation was assessed to be fairly unsuccessful in some cases due the occurrence of undissolved mullite and/or the formation of impurities such as hydroxysodalite with the zeolitic product. This study also showed that a high crystalline zeolite Na-P1 can be synthesized from South African coal fly ash using a 4-flat blade impeller at an agitation rate of 200 rpm during the ageing step at 47 °C for 48 hours followed by static hydrothermal treatment at 140 °C for 48 hours.

  17. Napájecí zdroj pro pulsní magnetronové naprašování

    OpenAIRE

    Chochola, Ondřej

    2008-01-01

    Předkládaná práce se zabývá teorií depozice velmi tenkých vrstev pomocí pulsního magnetronového naprašování a návrhem, realizací a testováním napájecího zdroje pro pulsní magnetronové naprašování.

  18. Identification of genomic differences between Campylobacter jejuni subsp. jejuni and C. jejuni subsp. doylei at the nap locus leads to the development of a C. jejuni subspeciation multiplex PCR method

    Directory of Open Access Journals (Sweden)

    Heath Sekou

    2007-02-01

    Full Text Available Abstract Background The human bacterial pathogen Campylobacter jejuni contains two subspecies: C. jejuni subsp. jejuni (Cjj and C. jejuni subsp. doylei (Cjd. Although Cjd strains are isolated infrequently in many parts of the world, they are obtained primarily from human clinical samples and result in an unusual clinical symptomatology in that, in addition to gastroenteritis, they are associated often with bacteremia. In this study, we describe a novel multiplex PCR method, based on the nitrate reductase (nap locus, that can be used to unambiguously subspeciate C. jejuni isolates. Results Internal and flanking napA and napB primer sets were designed, based on existing C. jejuni and Campylobacter coli genome sequences to create two multiplex PCR primer sets, nap mpx1 and nap mpx2. Genomic DNA from 161 C. jejuni subsp. jejuni (Cjj and 27 C. jejuni subsp. doylei (Cjd strains were amplified with these multiplex primer sets. The Cjd strains could be distinguished clearly from the Cjj strains using either nap mpx1 or mpx2. In addition, combination of either nap multiplex method with an existing lpxA speciation multiplex method resulted in the unambiguous and simultaneous speciation and subspeciation of the thermophilic Campylobacters. The Cjd nap amplicons were also sequenced: all Cjd strains tested contained identical 2761 bp deletions in napA and several Cjd strains contained deletions in napB. Conclusion The nap multiplex PCR primer sets are robust and give a 100% discrimination of C. jejuni subspecies. The ability to rapidly subspeciate C. jejuni as well as speciate thermophilic Campylobacter species, most of which are pathogenic in humans, in a single amplification will be of value to clinical laboratories in strain identification and the determination of the environmental source of campylobacterioses caused by Cjd. Finally, the sequences of the Cjd napA and napB loci suggest that Cjd strains arose from a common ancestor, providing clues as to

  19. Identification of two domains and distal histidine ligands to the four haems in the bacterial c-type cytochrome NapC; the prototype connector between quinol/quinone and periplasmic oxido-reductases.

    Science.gov (United States)

    Cartron, Michaël L; Roldán, M Dolores; Ferguson, Stuart J; Berks, Ben C; Richardson, David J

    2002-12-01

    NapC is a tetra-haem member of a family of bacterial membrane-anchored multi-haem c -type cytochromes implicated in electron transfer between membrane quinols and periplasmic enzymes. The water-soluble tetra-haem fragment of Paracoccus pantotrophus NapC has been expressed as a periplasmic protein (NapC(sol)) in Paracoccus denitrificans, P. pantotrophus and Escherichia coli. Site-specific mutagenesis of NapC(sol), combined with spectroscopic studies, suggests that each haem iron centre has bis -histidinyl co-ordination. Four proximal ligands arise from each of four Cys-Xaa-Xaa-Cys-His haem-binding motifs; candidates for the four distal ligands are His(81), His(99), His(174) and His(194). NapC(H81A), NapC(H99A), NapC(H174A) and NapC(H194A) mutants (with alanine substituted for each of the four candidate residues) have all been purified from E. coli. In each case, one of the haems has become high-spin, as judged by the presence of a broad absorption band between 620 nm and 650 nm for the oxidized cytochrome; this feature is absent for wild-type protein and presumably arises because of the absence of the distal histidine ligand from one of the haems. NapC(H81A) and NapC(H174A) are less well expressed in E. coli than NapC(H99A) and NapC(H194A) and cannot be detected when expressed in P. denitrificans or P. pantotrophus. In vitro and in vivo complementation studies demonstrate that the soluble periplasmic NapC can mediate electron transfer from quinols to the periplasmic nitrate reductase. This capacity was retained in vitro with the NapC(H99A) and NapC(H194A) mutants but was lost in vivo. A model for the structural organization of NapC(sol) into two domains, each containing a di-haem pair, is proposed. In this model, each haem pair obtains one distal haem ligand from its own domain and a second from the other domain. The suggestion of two domains is supported by observations that the 24 kDa NapC(sol) cleaves to yield a 12 kDa haem-staining band. Determination of the

  20. Perspectivas del uso de bacterias rizosféricas en el control de Pyricularia grisea (Cooke Sacc. en el cultivo del arroz (Oryza sativa L.

    Directory of Open Access Journals (Sweden)

    Yanelis Acebo Guerrero

    2011-04-01

    Full Text Available Prospect of the use of bacteria in the control Pyricularia grisea (Cooke Sacc. on rice (Oriza sativa L. Título corto: Bacterias rizosféricas para controlar la piriculariosis ResumenEl arroz es fuente de alimento para una gran parte de la población mundial, con alto promedio de consumo anual. En este cultivo las enfermedades de origen microbiano constituyen uno de los factores que inciden en la obtención de bajos rendimientos y calidad de los granos. La piriculariosis o añublo del arroz, causada por Pyricularia grisea, es la enfermedad más importante en este cultivo en América Latina, ya que puede provocar hasta el 100% de reducción de los rendimientos. Como parte de la estrategia de agricultura sostenible, se trata de controlar estos patógenos y lograr altos rendimientos del cultivo mediante una combinación adecuada de fertilizantes químicos y productos biológicos. En este sentido, la aplicación de inoculantes bacterianos constituidos por bacterias promotoras del crecimiento vegetal (Plant Growth- Promoting Bacteria, PGPB, por sus siglas en inglés ha constituido una alternativa ecológica que favorece la conservación del medioambiente y el ecosistema. Este trabajo tiene como objetivo abordar el estado actual y las perspectivas de uso de bacterias rizosféricas en el control de Pyricularia grisea en el cultivo del arroz, tratando algunos temas relevantes, como son las principales enfermedades que afectan al cultivo, los géneros de PGPB más utilizados para el control de las mismas y sus principales mecanismos de acción. Palabras clave: bacterias rizosféricas, arroz, piriculariosis. AbstractRice is an important food supply for a large part of the world population and its consumption rates are very high. Microbial diseases are one of the main causes that provoke low yields and low-quality spotted grains. Although fungi, bacteria and viruses are mostly the responsible for these losses, fungal diseases strike more frequently

  1. Influence of night-shift and napping at work on urinary melatonin, 17-β-estradiol and clock gene expression in pre-menopausal nurses.

    Science.gov (United States)

    Bracci, M; Copertaro, A; Manzella, N; Staffolani, S; Strafella, E; Nocchi, L; Barbaresi, M; Copertaro, B; Rapisarda, V; Valentino, M; Santarelli, L

    2013-01-01

    Night-workers experience disruption of the sleep-wake cycle and light at night which may increase breast cancer risk by suppressing the nocturnal melatonin surge, resulting in higher levels of circulating estrogens. Night-work may also deregulate peripheral clock genes which have been found to be altered in breast cancer. This study investigated urinary 6-sulfatoxymelatonin (aMT6s), serum 17-beta-estradiol levels in premenopausal shift nurses at the end of the night-shift compared to a control group of daytime nurses. Peripheral clock gene expression in lymphocytes were also investigated. All participants were sampled in the follicular phase of the menstrual cycle. The effect of nurses’ ability to take a short nap during the night-shift was also explored. The shift-work group had significantly lower aMT6s levels than daytime nurses independently of a nap. Night-shift napping significantly influences 17-beta-estradiol levels resulting in higher outcomes in nurses who do not take a nap compared to napping group and daytime workers. Peripheral clock genes expression investigated was not significantly different among the groups. Our findings suggest that shift nurses experience changes in aMT6s levels after a night-shift. Napping habits influence 17-beta-estradiol levels at the end of a night-shift. These findings might be related to the increased cancer risk reported in night-shift workers and suggest that a short nap during night-shifts may exert a positive effect. PMID:23489707

  2. A visual ERP study of impulse inhibition following a zaleplon-induced nap after sleep deprivation.

    Directory of Open Access Journals (Sweden)

    Qianru Zhang

    Full Text Available The side effects of a zaleplon-induced nap as a countermeasure in the reduction of impulse inhibition function decline following 30 h of sleep deprivation (SD were examined by event-related brain potentials. Sixteen adult participants performed a Go/NoGo task at five time points: (1 baseline; (2 after 30 h of SD; (3 upon sudden awakening, also called 2 h post-drug; (4 4 h post-drug; and (5 6 h post-drug. Behavior results show an increase in both reaction time and false alarm rates after SD and sudden awakening, and a marked decrease at 4 h and 6 h post-drug in zaleplon and placebo conditions. However, no difference was observed between the zaleplon condition and the placebo condition. In event-related potential (ERP reults compared with results obtained under control conditions, NoGo-P3 latencies significantly increased, whereas the Nogo-P3 amplitude decreased after 30 h of SD and sudden awakening in both the zaleplon condition and the placebo condition. These results indicate that SD attenuates resource allocation and error monitoring for NoGo stimuli. In addition, NoGo-P3 latencies were longer in the zaleplon condition compared with the placebo condition at sudden awakening. Additionally, the NoGo-P3 latencies were shorter in the zaleplon condition than in the placebo condition at 4 h and 6 h post-drug. These results indicate that zaleplon at a dose of 10 mg/day may help subjects achieve a better recovery or maintain better impulse inhibition function, although the side effects of zaleplon last at least 2 h post-drug.

  3. 1株拮抗酵母菌对柑橘绿霉病菌的抑制作用%Inhibitive activity of Kluyveromyces marxianus on Penicillium digitatum Sacc.

    Institute of Scientific and Technical Information of China (English)

    罗建军; 耿鹏; 胡美英; 黄慧斯; 贾建文

    2013-01-01

    以柑橘绿霉病菌(Penicillium digitatum Sacc.)为供试材料,研究拮抗酵母菌(Kluyverom yces marxianus)对柑橘采后绿霉病菌的抑制效果,并观察其对采后柑橘果实多酚氧化酶(PPO)、过氧化物酶(POD)和苯丙氨酸解氨酶(PAL)活性的影响.结果表明:拮抗酵母菌的菌株悬浮液和培养原液对柑橘采后绿霉病菌均有较好的抑制作用,但菌株培养上清液和热杀死液对柑橘绿霉病菌的抑制效果较差;与对照相比,接种拮抗菌与病原菌能够诱导柑橘果实PPO、POD和PAL活性的升高;拮抗酵母菌对柑橘绿霉病菌的抑菌机制与营养和空间的竞争以及诱导抗病性相关酶有关.%The inhibitive activity of Kluyveromyces marxianus against citrus green mold caused by Penicillium digitatum Sacc. was investigated, as well as its effect on the activities of polyphenol oxi-dase (PPO), peroxidase (POD) and phenylalanine ammonium-lyase (PAL). The results showed that the treatments of washed cell suspension and living cell suspension have better inhibiting effect, as compared to the control treatment; while the culture filtrate and autoclaved cell suspensions could exacerbate green mold decay. The application of K. marxianus could induce higher PPO, POD and PAL activity as compared to the control. It was suggested that the biocontrol mechanism might be competitive for nutrition and space, and contribute to the secretion of antagonistc substance.

  4. Long-Term Single and Joint Effects of Excessive Daytime Napping on the HOMA-IR Index and Glycosylated Hemoglobin: A Prospective Cohort Study.

    Science.gov (United States)

    Li, Xue; Pang, Xiuyu; Zhang, Qiao; Qu, Qiannuo; Hou, Zhigang; Liu, Zhipeng; Lv, Lin; Na, Guanqiong; Zhang, Wei; Sun, Changhao; Li, Ying

    2016-02-01

    This prospective cohort study was conducted to assess the duration of daytime napping and its effect combined with night sleep deprivation on the risk of developing high HOMA-IR (homeostasis model assessment of insulin resistance) index and disadvantageous changes in glycosylated hemoglobin (HbA1c) levels.A total of 5845 diabetes-free subjects (2736 women and 3109 men), 30 to 65 years of age, were targeted for this cohort study since 2008. Multiple adjusted Cox regression models were performed to evaluate the single and joint effects of daytime napping on the risk of an elevated HbA1c level and high HOMA-IR index.After an average of 4.5 years of follow-up, >30 minutes of daytime napping was significantly associated with an increased risk of an elevated HbA1c level (>6.5%) in men and women (all P trend 30 minutes napping and the combination of no sleep deprivation with >30 minutes daytime napping were all associated with an HbA1c level >6.5% (HR = 2.08, 95% CI = 1.24-3.51; HR = 4.00, 95% CI = 2.03-7.90; and HR = 2.05, 95% CI = 1.29-3.27, respectively). No sleep deprivation combined with >30 minutes daytime napping correlated with a high risk of an HbA1c level between 5.7% and 6.4% and high HOMA-IR index (HR = 2.12, 95% CI = 1.48-3.02; and HR = 1.35, 95% CI = 1.10-1.65, respectively).Daytime napping >30 minutes was associated with a high risk of an elevated HbA1c level and high HOMA-IR index. No sleep deprivation combined with napping >30 minutes carries a risk of abnormal glucose metabolism. Sleep deprivation combined with brief daytime napping <30 minutes was not associated with a risk for an elevated HbA1c level and high HOMA-IR index.

  5. A single administration of the peptide NAP induces long-term protective changes against the consequences of head injury: gene Atlas array analysis.

    Science.gov (United States)

    Romano, Jacob; Beni-Adani, Liana; Nissenbaum, Orlev Levy; Brenneman, Douglas E; Shohami, Esther; Gozes, Illana

    2002-01-01

    The femtomolar-acting eight-amino-acid peptide (NAP), derived from activity-dependent neuroprotective protein (ADNP), provides long-term protection against the deleterious effects of closed head injury (CHI) in mice. Fifteen minutes after injury, mice were divided into two groups, control and NAP-treated and a single subcutaneous injection of NAP or vehicle was administered. A third group served as sham-treated (not subjected to head trauma). Each mouse was assessed for its clinical function, using neurological severity score, at various time intervals following CHI, up to 30-45 d. Total cerebral cortex RNA was prepared from the site of injury of CHI mice, and from parallel regions in peptide-treated and sham brains. RNA was then reversed transcribed to yield radioactive cDNA preparations that were hybridized to Atlas array membranes containing 1200 cDNAs spots. Comparison of sham-treated individual mice showed differential expression levels of at least 15 mRNA species. Furthermore, results indicated that one of the genes that did not change among individuals but specifically increased after CHI and decreased after NAP treatment was the cell surface glycoprotein Mac-1 (CD11B antigen). Thus, Mac-1 is suggested as a marker for the long-term outcome of head injury and as a potential target for NAP protective actions.

  6. Cloning, Sequence Identification and Expression Analysis of NAP1L5 in Porcine Placenta at Different Gestation Stages%猪NAP1L5基因克隆、序列鉴定及在不同妊娠时期胎盘中的差异表达分析

    Institute of Scientific and Technical Information of China (English)

    顾婷; 赵书红; 李长春

    2012-01-01

    旨在获得猪NAP1L5基因的序列特征、组织表达及生物学功能等相关信息.本试验通过RT-PCR克隆了猪NAP1L5基因,并运用生物信息学方法分析了不同物种序列进化关系,运用荧光定量PCR技术检测了NAP1L5在梅山猪不同妊娠时期胎盘中的表达.序列分析结果表明,猪NAP1 L5基因CDS全长579 bp,编码193个氨基酸.其核苷酸序列与牛的相似性为89%,其中氨基酸序列包含一段保守的核小体组装蛋白(Nucleosome assembly protein,NAP)特征序列.荧光定量结果表明NAP1L5基因随着妊娠时期的增长呈上升表达,在26和50 d之间表达量差异极显著(P<0.01).以上结果支持了NAP1L5基因可能与猪胎儿营养获取及早期发育有关,为进一步研究猪NAP1 L5基因的功能奠定了基础.%The aim of this study was to obtain the information about sequence structure, tissue expression and biology function of porcine NAP1L5 gene. In the present study* the porcine NAP1L5 was cloned by RT-PCR, the sequence was analyzed by bioinformatics method, and its relative mRNA expression was detected by quantitative RT-PCR in porcine placenta at different gestation stages. Sequence analysis showed that the CDS region of the porcine NAP1L5 gene included 579 nucleotides, encoding 193 amino acids, and the sequence similarity of NAP1L5 between the pig and cattle was 89%. The amino acids sequence included the nucleosome assembly protein. The result of quantitative RT-PCR indicated that the expression of porcine NAP1L5 increased with the placenta development and there were significant difference between d26 and d50 of gestation stage (P<0. 01). These results suggest that NAP1L5 is probably related to the nutrition absorption and early development of porcine fetus, and make a foundation for the further study on the function of NAP1L5 gene in porcine.

  7. Spínaný zdroj 12/19V pro napájení notebooku v automobilu

    OpenAIRE

    Škunda, Michal

    2008-01-01

    Daná bakalárska práca sa zaoberá návrhom a realizáciou zvyšujúceho meniča STEP-UP pre napájanie notebooku v automobile. Úvodná časť prezentuje rozdelenie spínaných zdrojov, ďalej nasleduje samotná vožba a návrh spínaného zdroja. V práci sa nachádza konkrétny návrh tlmivky, návrh elektronického zapojenia a návrh plošného spoja. Pri návrhu plošného spoja je využitý program EAGLE. V poslednej časti sú vyobrazené jednotlivé priebehy prúdov a napätí charakterizujúce činnosť zdroja. Práca taktiež o...

  8. New insights into alkylammonium-functionalized clinoptilolite and Na-P1 zeolite: Structural and textural features

    Science.gov (United States)

    Muir, Barbara; Matusik, Jakub; Bajda, Tomasz

    2016-01-01

    The area of zeolites' application could be expanded by utilizing their surfaces. Zeolites are frequently modified to increase their hydrophobicity and to generate the negative charge of the surface. The main objective of the study was to investigate and compare the features of natural clinoptilolite and synthetic zeolite Na-P1 modified by selected surfactants involving quaternary ammonium salts. The FTIR study indicates that with increasing carbon chain length in the surfactant attached to the zeolites surface the molecules adopt a more disordered structure. FTIR was also used to determine the efficiency of surface modification. Thermal analysis revealed that the presence of surfactant results in additional exothermic effects associated with the breaking of electrostatic bonds between zeolites and surfactants. The mass losses are in line with ECEC and CHN data. The textural study indicates that the synthetic zeolite Na-P1 has better sorption properties than natural clinoptilolite. The modification process always reduces the SBET and porosity of the material. With an increasing carbon chain length of surfactants all the texture parameters decrease.

  9. Biallelic expression of Tssc4, Nap1l4, Phlda2 and Osbpl5 in adult cattle

    Indian Academy of Sciences (India)

    Mengnan Wang; Dongjie Li; Mingyue Zhang; Wenzhi Yang; Guojiang Wu; Yali Cui; Shijie Li

    2015-09-01

    Genomic imprinting of the Cdkn1c/Kcnq1ot1 region shows lack of conservation between human and mouse. This region has been reported to be associated with Beckwith–Wiedemann syndrome (BWS) and cancer. To increase our understanding of imprinted genes in bovine Cdkn1c/Kcnq1ot1 imprinting cluster, we assessed the imprinting status of four cattle genes (Tssc4, Nap1l4, Phlda2 and Osbpl5) in seven types of tissues: heart, liver, spleen, lung, kidney, skeletal muscle and subcutaneous fat using polymorphism-based sequencing approach. It was found that all the four genes showed biallelic expression in tissues in which transcripts were detected. Nap1l4 and Tssc4 were detected in all examined tissues, while the expression of Phlda2 and Osbpl5 was tissue-specific. Phlda2 was not detected in heart and subcutaneous fat, and Osbpl5 was not detected in spleen and skeletal muscle. In addition, identification of species-specific imprinted genes is necessary to understand the evolution of genomic imprinting and to elucidate mechanisms leading to allele-specific expression.

  10. Heterodimeric nitrate reductase (NapAB) from Cupriavidus necator H16: purification, crystallization and preliminary X-ray analysis

    International Nuclear Information System (INIS)

    Crystals of the oxidized form of the periplasmic nitrate reductase from Cupriavidus necator were obtained using polyethylene glycol 3350 as precipitant The periplasmic nitrate reductase from Cupriavidus necator (also known as Ralstonia eutropha) is a heterodimer that is able to reduce nitrate to nitrite. It comprises a 91 kDa catalytic subunit (NapA) and a 17 kDa subunit (NapB) that is involved in electron transfer. The larger subunit contains a molybdenum active site with a bis-molybdopterin guanine dinucleotide cofactor as well as one [4Fe–4S] cluster, while the small subunit is a di-haem c-type cytochrome. Crystals of the oxidized form of this enzyme were obtained using polyethylene glycol 3350 as precipitant. A single crystal grown at the High Throughput Crystallization Laboratory of the EMBL in Grenoble diffracted to beyond 1.5 Å at the ESRF (ID14-1), which is the highest resolution reported to date for a nitrate reductase. The unit-cell parameters are a = 142.2, b = 82.4, c = 96.8 Å, β = 100.7°, space group C2, and one heterodimer is present per asymmetric unit

  11. Hiina tänapäeva arhitektuur - karmiilmeline, aga põnev / Zhang Ke, Zhang Hong, Xiaodu Liu ; interv. Hanna Läkk ja Ene Läkk

    Index Scriptorium Estoniae

    Zhang Ke

    2006-01-01

    Intervjuu Hiina arhitektuuribüroo Standardarchitecture arhitektide Zhang Ke ja Zhang Hongiga ning arhitektuuribüroo Urbanus arhitekti Xiaodu Liuga Hollandis Hiina tänapäeva tutvustaval näitusel. Hiina arhitektide haridusest, oma arhitektuuribüroode töödest, tänapäeva hiina arhitektuurist, põhiprobleemidest

  12. Evaluation of the Efficacy of the H. pylori Protein HP-NAP as a Therapeutic Tool for Treatment of Bladder Cancer in an Orthotopic Murine Model.

    Science.gov (United States)

    Codolo, Gaia; Munari, Fabio; Fassan, Matteo; de Bernard, Marina

    2015-01-01

    Bladder cancer is one of the most common malignancies of the urogenital tract. Intravesical injection of Bacillus Calmette-Guérin (BCG) is the gold standard treatment for the high-grade non-muscle invasive bladder cancer (NMIBC). However, since the treatment-related side effects are relevant, newer biological response modifiers with a better benefit/side effects ratio are needed. The tumour microenvironment can influence both tumour development and therapy efficacy. In order to obtain a good model, it is desirable to implant tumour cells in the organ from which the cancer originates. In this protocol, we describe a method for establishing a tumour in the bladder cavity of female mice and subsequent delivery of therapeutic agents; the latter are exemplified by our use of Helicobacter pylori neutrophil activating protein (HP-NAP). A preliminary chemical burn of the mucosa, followed by the injection of mouse urothelial carcinoma cell line MB49 via urethral catheterization, enables the cells to attach to the bladder mucosa. After a period, required to allow an initial proliferation of the cells, mice are treated with HP-NAP, administrated again via catheterization. The anti-tumour activity of HP-NAP is evaluated comparing the tumour volume, the extent of necrosis and the degree of vascularization between vehicle- and HP-NAP-treated animals. PMID:26068073

  13. Performance of flash profile and napping with and without training for describing small sensory differences in a model wine

    DEFF Research Database (Denmark)

    Liu, Jing; Grønbeck, Marlene Schou; Di Monaco, Rosella;

    2016-01-01

    Publication date: March 2016 Source:Food Quality and Preference, Volume 48, Part A Author(s): Jing Liu, Marlene Schou Grønbeck, Rossella Di Monaco, Davide Giacalone, Wender L.P. Bredie Rapid sensory methods are a convenient alternative to conventional descriptive analysis suitable for quickly...... assessing sensory product differences. As these methods gain in popularity, assessments of their discriminability and reproducibility in food applications are increasingly needed. Moreover, it is of interest to explore whether small adjustments to the existing protocols could improve the results...... generation step and limiting the number of attributes for ranking gave a similar sample space. The Napping method could best highlight qualitative sample differences, whereas the Flash Profile provided a more precise product mapping on quantitative differences between model wines....

  14. A Truncated Arabidopsis NUCLEOSOME ASSEMBLY PROTEIN 1,AtNAP1;3T,Alters Plant Growth Responses to Abscisic Acid and Salt in the Atnap 1;3-2 Mutant

    Institute of Scientific and Technical Information of China (English)

    Zi-Qiang Liu; Juan Gao; Ai-Wu Dong

    2009-01-01

    Chromatin remodeling is thought to have crucial roles in plant adaptive response to environmental stimulus.Here,we report that,in Arebidopsis,the evolutionarily conserved histone chaperone,NUCLEOSOME ASSEMBLY PROTEIN 1 (NAP1),is involved in plant response to abscisic acid (ABA),a phytohormone important in stress adaptation.We show that simultaneous loss-of-function of AtNAP1;1,AtNAP1;2,and AtNAP1;3 (the triple mutant m123-1) caused a slight hypersensitive response to ABA in seedling growth.Strikingly,the other triple mutant m123-2 containing a different mutant allele of AtNAP1;3,the Atnap1;3-2 allele,showed a hyposensitive response to ABA and a decreased tolerance to salt stress.This ABAhyposensitive and salt response phenotype specifically associated with the Atnap1;3-2 mutant allele.We show that this mutant allele produced a truncated protein,AtNAP1;3T,which lacks 34 amino acids at the C-terminus compared to the wild-type protein AtNAP1;3.We further show that the heterozygous plants containing the Atnap1;3-2 mutant allele as well as transgenic plants overexpressing AtNAP1;3T exhibit ABA-hyposensitive phenotype.It thus indicates that AtNAP1;3T functions as a dominant negative factor in ABA response.The expression of some ABA-responsive genes,including genes encoding protein kinases and transcription regulators,was found perturbed in the mutant and in the AtNAP1;3T transgenic plants.Taken together,our study uncovered AtNAP1 proteins as positive regulators and AtNAP1;3T as a negative regulator in ABA signaling pathways,providing a novel link of chromatin remodeling to hormonal and stress responses.

  15. A Recombinant DNA Plasmid Encoding the sIL-4R-NAP Fusion Protein Suppress Airway Inflammation in an OVA-Induced Mouse Model of Asthma.

    Science.gov (United States)

    Liu, Xin; Fu, Guo; Ji, Zhenyu; Huang, Xiabing; Ding, Cong; Jiang, Hui; Wang, Xiaolong; Du, Mingxuan; Wang, Ting; Kang, Qiaozhen

    2016-08-01

    Asthma is a chronic inflammatory airway disease. It was prevalently perceived that Th2 cells played the crucial role in asthma pathogenesis, which has been identified as the important target for anti-asthma therapy. The soluble IL-4 receptor (sIL-4R), which is the decoy receptor for Th2 cytokine IL-4, has been reported to be effective in treating asthma in phase I/II clinical trail. To develop more efficacious anti-asthma agent, we attempt to test whether the Helicobacter pylori neutrophil-activating protein (HP-NAP), a novel TLR2 agonist, would enhance the efficacy of sIL-4R in anti-asthma therapy. In our work, we constructed a pcDNA3.1-sIL-4R-NAP plasmid, named PSN, encoding fusion protein of murine sIL-4R and HP-NAP. PSN significantly inhibited airway inflammation, decreased the serum OVA-specific IgE levels and remodeled the Th1/Th2 balance. Notably, PSN is more effective on anti-asthma therapy comparing with plasmid only expressing sIL-4R. PMID:27209195

  16. Studium povrchového napětí systémů využitelných v ultrasonografii.

    OpenAIRE

    Říkovská, Klára

    2014-01-01

    Cílem práce bylo studium povrchového napětí systémů využitelných v ultrasonografii. Bylo navrženo několik experimentů. Tyto experimenty se týkaly především měření povrchového napětí bublinovým tenziometrem BPA-800P. Bylo provedeno bližší zkoumání vlivu povrchového napětí komerčně dostupné látky SonoVue®, která ve své struktuře obsahuje mimo jiné dva fosfolipidy. Dále bylo zkoumáno několik samostatných fosfolipidů. Všechny látky byly rozpuštěny ve fyziologickém roztoku (0,15 M NaCl). Byl prově...

  17. The Arabidopsis Transcription Factor NAC016 Promotes Drought Stress Responses by Repressing AREB1 Transcription through a Trifurcate Feed-Forward Regulatory Loop Involving NAP.

    Science.gov (United States)

    Sakuraba, Yasuhito; Kim, Ye-Sol; Han, Su-Hyun; Lee, Byoung-Doo; Paek, Nam-Chon

    2015-06-01

    Drought and other abiotic stresses negatively affect plant growth and development and thus reduce productivity. The plant-specific NAM/ATAF1/2/CUC2 (NAC) transcription factors have important roles in abiotic stress-responsive signaling. Here, we show that Arabidopsis thaliana NAC016 is involved in drought stress responses; nac016 mutants have high drought tolerance, and NAC016-overexpressing (NAC016-OX) plants have low drought tolerance. Using genome-wide gene expression microarray analysis and MEME motif searches, we identified the NAC016-specific binding motif (NAC16BM), GATTGGAT[AT]CA, in the promoters of genes downregulated in nac016-1 mutants. The NAC16BM sequence does not contain the core NAC binding motif CACG (or its reverse complement CGTG). NAC016 directly binds to the NAC16BM in the promoter of ABSCISIC ACID-RESPONSIVE ELEMENT BINDING PROTEIN1 (AREB1), which encodes a central transcription factor in the stress-responsive abscisic acid signaling pathway and represses AREB1 transcription. We found that knockout mutants of the NAC016 target gene NAC-LIKE, ACTIVATED BY AP3/PI (NAP) also exhibited strong drought tolerance; moreover, NAP binds to the AREB1 promoter and suppresses AREB1 transcription. Taking these results together, we propose that a trifurcate feed-forward pathway involving NAC016, NAP, and AREB1 functions in the drought stress response, in addition to affecting leaf senescence in Arabidopsis. PMID:26059204

  18. Two measurements of the 22Na+p resonant scattering via thick-target inverse-kinematics method

    Directory of Open Access Journals (Sweden)

    Wang Y.B.

    2016-01-01

    Full Text Available 22Na is an important isotope for the study of extinct radioactivity, meanwhile its sufficiently long half life provides the possibility to observe live 22Na in nearby nova explosions. The 22Na(p,γ 23Mg is one of the key reactions that influence the 22Na abundance in nova ejecta. To study the proton resonant states in 23Mg relevant to the astrophysical 22Na(p,γ 23Mg reaction rates, two measurements have been carried out at the CRIB separator of University of Tokyo, and the RIBLL secondary beamline in Lanzhou, respectively. The 22Na secondary beam was produced via the 1H(22Ne, 22Nan charge exchange reaction. Thick-target inverse-kinematics method is applied to obtain the excitation function of 22Na+p elastic scattering. Extended gas target and solid state polyethylene foil were used in the two measurements, respectively, to map the different excitation energy region of the compound nucleus 23Mg. Several new resonant levels are observed and their contribution to the 22Na(p,γ 23Mg reaction rate is evaluated.

  19. Měnič pro napájení výkonové diody LED

    OpenAIRE

    Puczok, Václav

    2014-01-01

    Tato práce řeší návrh síťového napájecího zdroje pro výkonovou LED diodu určenou pro osvětlovací účely. Zdroj se skládá ze vstupního síťového vysokofrekvenčního filtru (EMI filtru), tlumícího část elektromagnetického rušení do sítě, dále aktivního usměrňovače (PFC obvodu) pro zlepšení účiníku odběru proudu ze sítě a hlavního jednočinného propustného měniče s impulzním transformátorem řízeného na konstantní výstupní proud. Práce je blíže zaměřena na návrh výkonové části zdroje, kam patří zejmé...

  20. Sleep duration, daytime napping, markers of obstructive sleep apnea and stroke in a population of southern China

    Science.gov (United States)

    Wen, Ye; Pi, Fu-Hua; Guo, Pi; Dong, Wen-Ya; Xie, Yu-Qing; Wang, Xiang-Yu; Xia, Fang-Fang; Pang, Shao-Jie; Wu, Yan-Chun; Wang, Yuan-Yuan; Zhang, Qing-Ying

    2016-01-01

    Sleep habits are associated with stroke in western populations, but this relation has been rarely investigated in China. Moreover, the differences among stroke subtypes remain unclear. This study aimed to explore the associations of total stroke, including ischemic and hemorrhagic type, with sleep habits of a population in southern China. We performed a case-control study in patients admitted to the hospital with first stroke and community control subjects. A total of 333 patients (n = 223, 67.0%, with ischemic stroke; n = 110, 23.0%, with hemorrhagic stroke) and 547 controls were enrolled in the study. Participants completed a structured questionnaire to identify sleep habits and other stroke risk factors. Least absolute shrinkage and selection operator (Lasso) and multiple logistic regression were performed to identify risk factors of disease. Incidence of stroke, and its subtypes, was significantly associated with snorting/gasping, snoring, sleep duration, and daytime napping. Snorting/gasping was identified as an important risk factor in the Lasso logistic regression model (Lasso’ β = 0.84), and the result was proven to be robust. This study showed the association between stroke and sleep habits in the southern Chinese population and might help in better detecting important sleep-related factors for stroke risk. PMID:27698374

  1. Modeling pilot interaction with automated digital avionics systems: Guidance and control algorithms for contour and nap-of-the-Earth flight

    Science.gov (United States)

    Hess, Ronald A.

    1990-01-01

    A collection of technical papers are presented that cover modeling pilot interaction with automated digital avionics systems and guidance and control algorithms for contour and nap-of-the-earth flight. The titles of the papers presented are as follows: (1) Automation effects in a multiloop manual control system; (2) A qualitative model of human interaction with complex dynamic systems; (3) Generalized predictive control of dynamic systems; (4) An application of generalized predictive control to rotorcraft terrain-following flight; (5) Self-tuning generalized predictive control applied to terrain-following flight; and (6) Precise flight path control using a predictive algorithm.

  2. Identification of nucleosome assembly protein 1 (NAP1) as an interacting partner of plant ribosomal protein S6 (RPS6) and a positive regulator of rDNA transcription

    International Nuclear Information System (INIS)

    The ribosomal protein S6 (RPS6) is a downstream component of the signaling mediated by the target of rapamycin (TOR) kinase that acts as a central regulator of the key metabolic processes, such as protein translation and ribosome biogenesis, in response to various environmental cues. In our previous study, we identified a novel role of plant RPS6, which negatively regulates rDNA transcription, forming a complex with a plant-specific histone deacetylase, AtHD2B. Here we report that the Arabidopsis RPS6 interacts additionally with a histone chaperone, nucleosome assembly protein 1(AtNAP1;1). The interaction does not appear to preclude the association of RPS6 with AtHD2B, as the AtNAP1 was also able to interact with AtHD2B as well as with an RPS6-AtHD2B fusion protein in the BiFC assay and pulldown experiment. Similar to a positive effect of the ribosomal S6 kinase 1 (AtS6K1) on rDNA transcription observed in this study, overexpression or down regulation of the AtNAP1;1 resulted in concomitant increase and decrease, respectively, in rDNA transcription suggesting a positive regulatory role played by AtNAP1 in plant rDNA transcription, possibly through derepression of the negative effect of the RPS6-AtHD2B complex. - Highlights: • Nucleosome assembly protein 1 (AtNAP1) interacts with RPS6 as well as with AtHD2B. • rDNA transcription is regulated S6K1. • Overexpression or down regulation of AtNAP1 results in concomitant increase or decrease in rDNA transcription

  3. Identification of nucleosome assembly protein 1 (NAP1) as an interacting partner of plant ribosomal protein S6 (RPS6) and a positive regulator of rDNA transcription

    Energy Technology Data Exchange (ETDEWEB)

    Son, Ora [Department of Biological Science, Sookmyung Women' s University, Seoul 140-742 (Korea, Republic of); Kim, Sunghan [Department of Biological Science, Sookmyung Women' s University, Seoul 140-742 (Korea, Republic of); Department of Plant Science, Plant Genomics and Breeding Institute, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 151-921 (Korea, Republic of); Shin, Yun-jeong [Department of Biological Science, Sookmyung Women' s University, Seoul 140-742 (Korea, Republic of); Kim, Woo-Young [College of Pharmacy, Sookmyung Women' s University, Seoul 140-742 (Korea, Republic of); Koh, Hee-Jong, E-mail: heejkoh@snu.ac.kr [Department of Plant Science, Plant Genomics and Breeding Institute, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 151-921 (Korea, Republic of); Cheon, Choong-Ill, E-mail: ccheon@sookmyung.ac.kr [Department of Biological Science, Sookmyung Women' s University, Seoul 140-742 (Korea, Republic of)

    2015-09-18

    The ribosomal protein S6 (RPS6) is a downstream component of the signaling mediated by the target of rapamycin (TOR) kinase that acts as a central regulator of the key metabolic processes, such as protein translation and ribosome biogenesis, in response to various environmental cues. In our previous study, we identified a novel role of plant RPS6, which negatively regulates rDNA transcription, forming a complex with a plant-specific histone deacetylase, AtHD2B. Here we report that the Arabidopsis RPS6 interacts additionally with a histone chaperone, nucleosome assembly protein 1(AtNAP1;1). The interaction does not appear to preclude the association of RPS6 with AtHD2B, as the AtNAP1 was also able to interact with AtHD2B as well as with an RPS6-AtHD2B fusion protein in the BiFC assay and pulldown experiment. Similar to a positive effect of the ribosomal S6 kinase 1 (AtS6K1) on rDNA transcription observed in this study, overexpression or down regulation of the AtNAP1;1 resulted in concomitant increase and decrease, respectively, in rDNA transcription suggesting a positive regulatory role played by AtNAP1 in plant rDNA transcription, possibly through derepression of the negative effect of the RPS6-AtHD2B complex. - Highlights: • Nucleosome assembly protein 1 (AtNAP1) interacts with RPS6 as well as with AtHD2B. • rDNA transcription is regulated S6K1. • Overexpression or down regulation of AtNAP1 results in concomitant increase or decrease in rDNA transcription.

  4. Design of Cloth Stable Run Infrared Controller for Napping Machine%拉毛机布匹运行稳定红外线控制器设计

    Institute of Scientific and Technical Information of China (English)

    王进满

    2013-01-01

    In process of fabricating naps, cloth walks with the rotating of drum at napping machine. Deviation of the walking pace occurs occasionally, and a manual intervention is inevitable in most of times. These would influence on the quality and cost of product. In order to solve this problem, a stable infrared controller is designed in this paper. It can monitor the cloth run in real time by using of automatic alignment, which reduces the labor intensity and improves production efficiency.%在拉毛布匹过程中,布匹随着拉毛滚筒转动在绲道上运行。布匹在绲道上行走时经常走偏,需靠操作工人拉正。这不仅影响产品的质量控制,同时也提高了生产成本。为解决此生产难题,本文设计了布匹运行稳定红外线控制器,它实现了对布匹运行实时监控,当布匹偏离绲道时,通过红外线自动控制功能对布匹自动找正,这不仅减轻了操作工人的劳动强度,也提高了生产效率。

  5. Synthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) as an Eco-Friendly, Inexpensive, and Efficient Catalyst

    OpenAIRE

    Ali Gharib; Nader Noroozi Pesyan; Leila Vojdani Fard; Mina Roshani

    2014-01-01

    This paper describes an alternative and simple procedure for the synthesis of Ibuprofen using Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) (SPNPs), as an eco-friendly, inexpensive, and efficient catalyst. High yields, simplicity of operation, and easy work-up procedure are some advantages of this protocol. Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) (SPNPs) offer the advantages of a higher hydrolytic and thermal stability. The salient features of Preys...

  6. Variation in PTCHD2, CRISP3, NAP1L4, FSCB, and AP3B2 associated with spherical equivalent

    Science.gov (United States)

    Chen, Fei; Duggal, Priya; Klein, Barbara E.K.; Lee, Kristine E.; Truitt, Barbara; Klein, Ronald; Iyengar, Sudha K.

    2016-01-01

    Purpose Ocular refraction is measured in spherical equivalent as the power of the external lens required to focus images on the retina. Myopia (nearsightedness) and hyperopia (farsightedness) are the most common refractive errors, and the leading causes of visual impairment and blindness in the world. The goal of this study is to identify rare and low-frequency variants that influence spherical equivalent. Methods We conducted variant-level and gene-level quantitative trait association analyses for mean spherical equivalent, using data from 1,560 individuals in the Beaver Dam Eye Study. Genotyping was conducted using the Illumina exome array. We analyzed 34,976 single nucleotide variants and 11,571 autosomal genes across the genome, using single-variant tests as well as gene-based tests. Results Spherical equivalent was significantly associated with five genes in gene-based analysis: PTCHD2 at 1p36.22 (p = 3.6 × 10−7), CRISP3 at 6p12.3 (p = 4.3 × 10−6), NAP1L4 at 11p15.5 (p = 3.6 × 10−6), FSCB at 14q21.2 (p = 1.5 × 10−7), and AP3B2 at 15q25.2 (p = 1.6 × 10−7). The variant-based tests identified evidence suggestive of association with two novel variants in linkage disequilibrium (pairwise r2 = 0.80) in the TCTE1 gene region at 6p21.1 (rs2297336, minor allele frequency (MAF) = 14.1%, β = –0.62 p = 3.7 × 10−6; rs324146, MAF = 16.9%, β = –0.55, p = 1.4 × 10−5). In addition to these novel findings, we successfully replicated a previously reported association with rs634990 near GJD2 at 15q14 (MAF = 47%, β = –0.29, p=1.8 × 10−3). We also found evidence of association with spherical equivalent on 2q37.1 in PRSS56 at rs1550094 (MAF = 31%, β = –0.33, p = 1.7 × 10−3), a region previously associated with myopia. Conclusions We identified several novel candidate genes that may play a role in the control of spherical equivalent. However, further studies are needed to replicate these findings. In addition, our results contribute to the

  7. Kollektiivne töö, rohujuuredemokraatia ja opositsioonikultuuri visuaalsed vormid tänapäeva Eestis = Collective work, grassroots democracy and visual forms of opposition culture in contemporary Estonia / Airi Triisberg

    Index Scriptorium Estoniae

    Triisberg, Airi, 1982-

    2009-01-01

    Kokkupuutepunktidest sotsiaalsete liikumiste ja kaasaegse kunsti vahel tänapäeva Eestis, keskendudes kollektiivse ja sekkuva iseloomuga praktikatele avalikus ruumis. Prussakovi nimelise jalgrattaühingu Vabaduse väljaku aktsioonist Tallinnas, Linnalabori katuseaia jt. projektidest, "vabaduse plakati" aktsioonist, Johnson&Johnson "Paldiski projektist" jm.

  8. Vývoj vysokofrekvenčních zkušebních zdrojů vysokého a velmi vysokého napětí

    OpenAIRE

    Talaš, Pavel

    2012-01-01

    Tato bakalářská práce se zabývá vysokofrekvenčními zdroji vysokého a velmi vysokého napětí. Práce je rozdělena do dvou částí. V první části jsou rozebrány zdroje vysokého napětí po stránce historické, doplněné o základní charakteristiky. Speciální pozornost věnována TC (Tesla Coil). V druhé části je proveden matematický návrh Teslova transformátoru.

  9. Synthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2 as an Eco-Friendly, Inexpensive, and Efficient Catalyst

    Directory of Open Access Journals (Sweden)

    Ali Gharib

    2014-01-01

    Full Text Available This paper describes an alternative and simple procedure for the synthesis of Ibuprofen using Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2 (SPNPs, as an eco-friendly, inexpensive, and efficient catalyst. High yields, simplicity of operation, and easy work-up procedure are some advantages of this protocol. Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2 (SPNPs offer the advantages of a higher hydrolytic and thermal stability. The salient features of Preyssler’s anion are availability, nontoxicity and reusability. We believe this methodology can find usefulness in organic synthesis.

  10. Prenatal Care

    Science.gov (United States)

    ... am thinking about getting pregnant. How can I take care of myself? You should start taking care of ... What should I do — or not do — to take care of myself and my unborn baby? Follow these ...

  11. Critical Care

    Science.gov (United States)

    Critical care helps people with life-threatening injuries and illnesses. It might treat problems such as complications from surgery, ... attention by a team of specially-trained health care providers. Critical care usually takes place in an ...

  12. Palliative Care

    Science.gov (United States)

    Palliative care is treatment of the discomfort, symptoms, and stress of serious illness. It provides relief from distressing symptoms ... of the medical treatments you're receiving. Hospice care, care at the end of life, always includes ...

  13. Self Care

    Science.gov (United States)

    ... Care Connections Experiences Research Learning Evaluation Print Email Self Care If you are living with a chronic ... help you cope can make a real difference. Self-care techniques are things you can do for ...

  14. Deformační a napěťová analýza lebečního fixátoru

    OpenAIRE

    Chamrad, Jakub

    2016-01-01

    To, jak se bude implantát chovat v lebce, je velmi důležitým faktorem, který ovlivňuje jeho funkci. K ovlivnění dochází především vnějšími silami a nitrolebečním tlakem. Tato zatížení mohou způsobit pohyb implantátu a poškození živých tkání. Tato práce shrnuje poznatky a analýzy, týkající se rekonstrukce poranění lebky. Srovnání implantátů z různých materiálů a fixátorů je založené na napěťově-deformační analýze implantátu, zatíženého vnějšími silami a nitrolebečním tlakem. Mechanical beha...

  15. Fully automatic guidance and control for rotorcraft nap-of-the-Earth flight following planned profiles. Volume 1: Real-time piloted simulation

    Science.gov (United States)

    Clement, Warren F.; Gorder, Peter J.; Jewell, Wayne F.

    1991-01-01

    Developing a single-pilot, all-weather nap-of-the-earth (NOE) capability requires fully automatic NOE (ANOE) navigation and flight control. Innovative guidance and control concepts are investigated in a four-fold research effort that: (1) organizes the on-board computer-based storage and real-time updating of NOE terrain profiles and obstacles in course-oriented coordinates indexed to the mission flight plan; (2) defines a class of automatic anticipative pursuit guidance algorithms and necessary data preview requirements to follow the vertical, lateral, and longitudinal guidance commands dictated by the updated flight profiles; (3) automates a decision-making process for unexpected obstacle avoidance; and (4) provides several rapid response maneuvers. Acquired knowledge from the sensed environment is correlated with the forehand knowledge of the recorded environment (terrain, cultural features, threats, and targets), which is then used to determine an appropriate evasive maneuver if a nonconformity of the sensed and recorded environments is observed. This four-fold research effort was evaluated in both fixed-based and moving-based real-time piloted simulations, thereby, providing a practical demonstration for evaluating pilot acceptance of the automated concepts, supervisory override, manual operation, and re-engagement of the automatic system. Volume one describes the major components of the guidance and control laws as well as the results of the piloted simulations. Volume two describes the complete mathematical model of the fully automatic guidance system for rotorcraft NOE flight following planned flight profiles.

  16. Rozdělení proudů a napětí při nesouměrných zkratech

    OpenAIRE

    Kakrda, Michal

    2012-01-01

    Cílem této bakalářské práce je seznámení s výpočtem napěťových a proudových poměrů při nesouměrných zkratech. První část práce je zaměřena na přiblížení problematiky zkratů obecně. Popisuje příčiny vzniku zkratů, jejich dělení a průběhy. Další část práce ukazuje způsoby výpočtu jednotlivých druhů zkratů a to především se zaměřením na metodu souměrných složek. Poslední část práce je pak zaměřena na použití zjištěných poznatků k výpočtu poměrů na konkrétní zadané elektrické sítí. Výpočet je pro...

  17. Sedimentological interpretation and stratigraphical position of glacigenic deposits in the Napęków area (Holy Cross Mountains, Poland)

    Science.gov (United States)

    Ludwikowska-Kędzia, Małgorzata; Pawelec, Halina; Adamiec, Grzegorz

    2015-12-01

    The identification of depositional conditions and stratigraphical position of glacigenic deposits in the Napęków area is important for the genetic and stratigraphical interpretation of Quaternary deposits in the central part of the Holy Cross Mountains, as well as for a revision of the course and extent of Middle Polish (Saalian) glaciations. These deposits comprise a series of diamictons which occur between sandy-gravelly deposits. Based on results of macro- and microscopic sedimentological investigations, analysis of heavy mineral composition, roundness and frosting of quartz grains, as well as OSL dating, this complex must have formed during the Odranian Glaciation (Drenthe, Saalian, MIS 6). Sandy-gravelly deposits are of fluvioglacial and melt-out origin. Diamictons represent subglacial traction till. Their facies diversity is a result of variations in time and space, complex processes of deposition and deformation, responsible for their formation at the base of the active ice sheet. This glacigenic depositional complex was transformed by erosion-denudation and aeolian processes in a periglacial environment during the Vistulian (Weichselian, MIS 5d-2).

  18. A national survey (NAP5-Ireland baseline) to estimate an annual incidence of accidental awareness during general anaesthesia in Ireland.

    LENUS (Irish Health Repository)

    Jonker, W R

    2014-06-29

    As part of the 5th National Audit Project of the Royal College of Anaesthetists and the Association of Anaesthetists of Great Britain and Ireland concerning accidental awareness during general anaesthesia, we issued a questionnaire to every consultant anaesthetist in each of 46 public hospitals in Ireland, represented by 41 local co-ordinators. The survey ascertained the number of new cases of accidental awareness becoming known to them for patients under their care or supervision for a calendar year, as well as their career experience. Consultants from all hospitals responded, with an individual response rate of 87% (299 anaesthetists). There were eight new cases of accidental awareness that became known to consultants in 2011; an estimated incidence of 1:23 366. Two out of the eight cases (25%) occurred at or after induction of anaesthesia, but before surgery; four cases (50%) occurred during surgery; and two cases (25%) occurred after surgery was complete, but before full emergence. Four cases were associated with pain or distress (50%), one after an experience at induction and three after experiences during surgery. There were no formal complaints or legal actions that arose in 2011 related to awareness. Depth of anaesthesia monitoring was reported to be available in 33 (80%) departments, and was used by 184 consultants (62%), 18 (6%) routinely. None of the 46 hospitals had a policy to prevent or manage awareness. Similar to the results of a larger survey in the UK, the disparity between the incidence of awareness as known to anaesthetists and that reported in trials warrants explanation. Compared with UK practice, there appears to be greater use of depth of anaesthesia monitoring in Ireland, although this is still infrequent.

  19. Entrevista e análise do discurso de um usuário de um NAPS: Sandro e a injustiça institucionalizada

    Directory of Open Access Journals (Sweden)

    Sérgio Bacchi Machado

    2010-09-01

    Full Text Available No presente artigo analisou-se a transcrição de uma entrevista com um usuário de um Núcleo de Atenção Psicossocial (NAPS do Estado de São Paulo segundo o método de análise institucional de discurso. Visou-se, com isso, ao estudo da constituição do sujeito no discurso - o que implica tanto o seu vínculo com a instituição quanto a interlocução que se configura com o entrevistador no ato mesmo da entrevista. Empreendendo uma analítica do discurso do usuário - em detrimento de classificações psiquiátricas ou psicopatológicas impostas aos sujeitos -, realizou-se o delineamento de sua singularidade por meio da positivação de seu discurso. Buscou-se, ainda, mapear as correlações de força presentes em diversos temas recorrentes em sua fala, tais como a injustiça, a violência, os médicos, a sexualidade, medicamentos e cotidiano institucional. Por fim, propôs-se uma abordagem que, longe de corroborar com uma concepção da verdade como ente subterrâneo aguardando ser descoberto pelo pesquisador, toma o par usuário/instituição como uma produção única e indissociável.

  20. 基于条件概率的短时睡眠状态实时估计%Sleep level estimation based on conditional probability for nap

    Institute of Scientific and Technical Information of China (English)

    王蓓; 张俊民; 张涛; 王行愚

    2015-01-01

    目的:根据脑电信号的特征,提出基于条件概率的睡眠状态实时估计方法,为睡眠监测提供反映睡眠状态连续变化的客观评价依据。方法在白天短时睡眠过程中,同步采集了4导与睡眠相关的脑电信号( C3-A2,C4-A1,O1-A2,O2-A1),对每5秒记录数据进行傅里叶变换,分别计算了8~13 Hz和2~7 Hz 的脑电节律能量占空比特征参数。主要方法包含了学习和测试两个阶段:在学习阶段,根据训练数据获得脑电特征参数的概率密度分布;在测试阶段,根据当前特征,得到各睡眠分期的条件概率,并计算获得睡眠状态的估计值。结果分析和测试了12名受试者的短时睡眠数据。通过与睡眠分期的人工判读结果相比较,睡眠状态估计值呈现了睡眠深度的连续变化。觉醒期的显著性差异为2.94,睡眠一期和二期分别为1.78和1.62,分析结果符合实际规律。结论本文所定义的睡眠状态估计值蕴含了睡眠分期的特征,较好地反映了睡眠阶段在持续和过渡期间的连续变化过程,能够为白天短时睡眠状态分析提供实时监测和分析的客观评价依据。%Objective According to the characteristics of electroencephalograph( EEG),an automatic sleep level estimation method based on conditional probability is developed. The ultimate purpose is to obtain and realize the real-time sleep level evaluation. Methods There are 4 EEG channels(O2 -A1 ,O1 -A2 ,C4 -A1 , C3 -A2 )recorded during nap. For every 5-second data,two characteristic parameters of ratio of EEG rhythms (8-13 Hz,2-7 Hz)are calculated after fast Fourier transformation(FFT). The main method consists of two models:learning and testing. During the learning stage,the probability density functions of EEG parameters are obtained based on the training data. During the testing stage,the sleep level is estimated based on the conditional probability of sleep stages. Results The

  1. Tracheostomy care

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000076.htm Tracheostomy care To use the sharing features on this ... through your nose and mouth. Caring for Your Tracheostomy Once the hole in your neck is not ...

  2. Daily Care

    Science.gov (United States)

    ... to Know Online Tools Enhancing Daily Life Daily Plan Activities Communication Food & Eating Music & Art Personal Care Incontinence Bathing ... Tweet Email | Print Create a Daily Routine Daily Plan Activities Communication Food/Eating Get Tips on Personal Care Bathing ...

  3. Continuing Care

    Science.gov (United States)

    ... Care Obesity at Midlife May Speed Alzheimer’s Onset Hello from my mom Easing the Behavior Problems of ... Managers Continuing Care FOR MORE ARTICLES CLICK HERE Hello from my mom Common Estate Planning Errors Alzheimer’s ...

  4. Pin care

    Science.gov (United States)

    ... gov/pubmed/24302374 . Nagy K. Discharge instructions for wound cares. The American Association of the Surgery of Trauma. www.aast.org/discharge-instructions-for-wound-cares . Accessed May 13, 2016.

  5. Comparing Care

    NARCIS (Netherlands)

    Evert Pommer; Isolde Woittiez; John Stevens

    2007-01-01

    Home care is one of the most important means of compensating for disabilities and ensuring continuity in people's daily functioning. Home care services in the Netherlands have recently been transferred from a national social security provision for long-term care to a local social service. In most ot

  6. Evaluation on Anti-inflammatory and Immunoregulatory Activity of Gastrodin Biosynthetized by Armillaria Luteo-virens Sacc%黄绿蜜环菌生物合成的天麻素抗炎及免疫调节活性评价

    Institute of Scientific and Technical Information of China (English)

    冯宇; 章海锋; 傅明亮; 刘晓杰; 董亚晨; 陈启和

    2011-01-01

    The anti-inflammatory and immunomodulatory activity of gastrodin synthesized by Armillaria luteo-virens Sacc were studied in this paper. The results showed that synthesized gastrodin can significantly inhibited mouse ear swelling and granuloma, it suggested that the gastrodin has a good anti-inflammatory effect. In the carbon clearance test, gastrodin can dramatically increase the mouse carbon clearance index and phagocytic index, in mouse lymphocyte trans-formation test, gastrodin promoted the proliferation of mouse lymphocyte, in the experiment on NK cells, gastrodin can distinctly improve the phagocytosis of target cells, these experimental result suggested that the synthesized gastrodin has a good immunoregulatory effect.%对黄绿蜜环菌生物合成的天麻素进行抗炎及免疫调节活性探讨.试验结果表明,生物合成的天麻素对小鼠耳廓肿胀和小鼠肉芽肿有明显的抑制作用,抗炎效果很好.在碳廓清试验中,天麻素能够较显著地提高小鼠碳廓清指数和吞噬指数.在小鼠淋巴细胞转化试验中,天麻素促进了淋巴细胞的增殖.对NK细胞影响试验中,天麻素能够明显提高靶细胞的吞噬能力,具有很好的免疫调节作用.

  7. Advance care directives

    Science.gov (United States)

    ... advance directive; Do-not-resuscitate - advance directive; Durable power of attorney - advance care directive; POA - advance care directive; Health care agent - advance care directive; Health care proxy - ...

  8. Biologists napping while work militarized.

    Science.gov (United States)

    Dando, Malcolm

    2009-08-20

    As researchers discover more agents that alter mental states, the Chemical Weapons Convention needs modification to help ensure that the life sciences are not used for hostile purposes, says Malcolm Dando.

  9. 幼儿在园午睡存在的问题及对策研究%Research on the Problems in Children's Nap in Kinder-garten and the Countermeasures

    Institute of Scientific and Technical Information of China (English)

    伊翠娟

    2013-01-01

    午睡是幼儿在幼儿园生活中的一个重要环节,对幼儿身心发展有着十分重要的作用,有利于良好生活习惯的养成和下午的学习活动。然而,幼儿在园午睡却存在着很多问题。因此要提高幼儿园、教师和家长对幼儿午睡重要性的认识,合理调整幼儿在园午睡时间,创设良好的午睡环境,促进幼儿良好午睡习惯的养成,使其身心健康发展。%The nap is an important part of children's kindergarten life, for it plays an important role in children's physical and psy-chological development and the development of their good living habit, but there exist many problems in children's nap. This pa-per mainly proposes countermeasures for the exiting problems.

  10. Supportive Care.

    Science.gov (United States)

    Olsen, Pia Riis; Lorenzo, Rosalía

    2016-01-01

    This chapter takes its point of departure in psychosocial aspects of supportive care in adolescent and young adult cancer care. The purpose is to describe some of the challenges that these young people face following a cancer diagnosis and guide healthcare professionals in how to provide care that improves the quality of life. In most hospitals and healthcare systems, adolescents and young adults are cared for and treated in settings for children or adults. Accordingly, healthcare professionals may lack attention to and knowledge about what characterize young peoples' life situation, their special needs and how to meet them. The topics we include in the chapter are the following: the youth friendly environment, social support and social network, parents, information during a psychosocial crisis event, the use of HEADSS, peer support, fertility, body image and self-esteem, after treatment and future challenges and palliative and end of life care. PMID:27595353

  11. Entre Hacienda Real y poderes locales: los intentos de reformar las finanzas municipales del reino de Napóles en los siglos XVI y XVII

    Directory of Open Access Journals (Sweden)

    Gaetano SABATINI

    2009-12-01

    Full Text Available RESUMEN: Durante los sesenta años de transición entre los siglos XVI y XVII se concentran los mayores esfuerzos llevados a cabo en la edad de los Austrias para aumentar el control del poder central sobre la gestión de las finanzas municipales del reino de Napóles, con la doble finalidad de garantizar la regularidad del producto fiscal proveniente de las comunidades y, al mismo tiempo, constituir una reserva de capitales a la cual el soberano pudiera acceder con facilidad y con condiciones menos onerosas que las aplicadas habitualmente por los banqueros. Ambas finalidades son la consecuencia de las crecientes exigencias financieras de la Corona que se registran en el mismo período y que llevan a un crecimiento rápido y vertiginoso de los recursos enviados fuera de los límites del reino, principalmente a Lombardía o a Flandes, para asistir a los ejércitos de la Monarquía. A pesar de la determinación demostrada, la Hacienda Real nunca consigue controlar de una forma completa las finanzas urbanas, sobre todo por la oposición de los poderes económicos —tanto de la capital y como de las provincias del reino— que habrían resultado afectados. A partir de los años 30 del siglo XVII los proyectos de reforma se retiran a cambio del compromiso de los patriciados de las ciudades de cobrar los impuestos y enviarlos a la Corte del modo más puntual. Profundizar en las modalidades a través de las cuales estos proyectos de reformas son llevados a cabo,aunque de modo inacabado, permite comprender mejor la índole de las finanzas urbanas como espacio de poder contendido entre élites dirigentes ciudadanas y Hacienda Real.ABSTRACT: The most important efforts to reform the urban finances realized in the Kingdom of Naples at the time of Spanish rule were done between 1570 and 1630. The increasing financial needing, due to an enormous military expense, obliged the Spanish Monarchy to make any attempt in order to insure the regularity of the tax

  12. Theoretical Issues Associated with the Evaluation of the Technical Condition of Avionic Hydraulic Drives on the Basis of Information Received from Means for Unbiased Flight Control of Aircrafts / Teoretyczne Aspekty Oceny Stanu Technicznego Lotniczego Napędu Hydraulicznego Na Podstawie Informacji Ze Środków Obiektywnej Kontroli Lotu

    Directory of Open Access Journals (Sweden)

    Ułanowicz Leszek

    2014-12-01

    Full Text Available Celem pracy jest przedstawienie możliwości wykorzystania do oceny stanu technicznego lotniczego napędu hydraulicznego metody polegającej na wykorzystaniu informacji ze środków obiektywnej kontroli lotu. Największą wiarygodność oraz wartość diagnostyczną mają dwa parametry kontrolne uzyskane ze środków obiektywnej kontroli lotu. Pierwszy to czas spadku ciśnienia w lotniczym napędzie hydraulicznym od górnej wartości pomiarowej do dolnej wartości pomiarowej po wyłączeniu zespołu napędowego. Drugi to czas spadku ciśnienia poniżej określonej wartości i jego powrotu do tej wartości w czasie ruchu silnika hydraulicznego. Proponowana metoda daje możliwość bieżącej oceny stanu technicznego lotniczego napędu hydraulicznego, jest szybka i bezkosztowa.

  13. Hospice Care

    Science.gov (United States)

    ... your care. Other team members may include a music therapist, physical therapist, speech therapist or occupational therapist. ... to the Terms and Conditions and Privacy Policy Popular Articles 1 Understanding Blood Pressure Readings 2 Sodium ...

  14. Multidisciplinary Care.

    Science.gov (United States)

    Daly, Megan E; Riess, Jonathan W

    2016-01-01

    Optimal multidisciplinary care of the lung cancer patient at all stages should encompass integration of the key relevant medical specialties, including not only medical, surgical, and radiation oncology, but also pulmonology, interventional and diagnostic radiology, pathology, palliative care, and supportive services such as physical therapy, case management, smoking cessation, and nutrition. Multidisciplinary management starts at staging and tissue diagnosis with pathologic and molecular phenotyping, extends through selection of a treatment modality or modalities, management of treatment and cancer-related symptoms, and to survivorship and end-of-life care. Well-integrated multidisciplinary care may reduce treatment delays, improve cancer-specific outcomes, and enhance quality of life. We address key topics and areas of ongoing investigation in multidisciplinary decision making at each stage of the lung cancer treatment course for early-stage, locally advanced, and metastatic lung cancer patients. PMID:27535399

  15. Caring Encounters

    Science.gov (United States)

    Gunn, Alyson

    2012-01-01

    Children with autism may seem to not care about things or have the same range of emotions as those of us who see them and care for them. But they do have empathy and they can be taught how to communicate it, says the author, a teacher of children with autism. We simply need to listen to them, watch them, and be with them in their moment.

  16. Integrating Palliative Care into Primary Care.

    Science.gov (United States)

    Gorman, Rosemary D

    2016-09-01

    Improved quality of life, care consistent with patient goals of care, and decreased health care spending are benefits of palliative care. Palliative care is appropriate for anyone with a serious illness. Advances in technology and pharmaceuticals have resulted in increasing numbers of seriously ill individuals, many with a high symptom burden. The numbers of individuals who could benefit from palliative care far outweighs the number of palliative care specialists. To integrate palliative care into primary care it is essential that resources are available to improve generalist palliative care skills, identify appropriate patients and refer complex patients to specialist palliative care providers.

  17. Wound Care in Primary Health Care

    OpenAIRE

    Nail Ersoz; Ismail Hakki Ozerhan; Fatih Zor

    2008-01-01

    Wound care starts with occuring of wound. Primary health care wound care important as to affect on quality of healing. It is given information about the types of wounds, brief wound physiopathology and presented the options of wound care to primary health care wound care proffessionals in this article. Wound care must be done in a systematic process by health care professionals. [TAF Prev Med Bull 2008; 7(1.000): 71-74

  18. Wound Care in Primary Health Care

    Directory of Open Access Journals (Sweden)

    Nail Ersoz

    2008-02-01

    Full Text Available Wound care starts with occuring of wound. Primary health care wound care important as to affect on quality of healing. It is given information about the types of wounds, brief wound physiopathology and presented the options of wound care to primary health care wound care proffessionals in this article. Wound care must be done in a systematic process by health care professionals. [TAF Prev Med Bull. 2008; 7(1: 71-74

  19. Wound Care in Primary Health Care

    Directory of Open Access Journals (Sweden)

    Nail Ersoz

    2008-02-01

    Full Text Available Wound care starts with occuring of wound. Primary health care wound care important as to affect on quality of healing. It is given information about the types of wounds, brief wound physiopathology and presented the options of wound care to primary health care wound care proffessionals in this article. Wound care must be done in a systematic process by health care professionals. [TAF Prev Med Bull 2008; 7(1.000: 71-74

  20. Wound Care.

    Science.gov (United States)

    Balsa, Ingrid M; Culp, William T N

    2015-09-01

    Wound care requires an understanding of normal wound healing, causes of delays of wound healing, and the management of wounds. Every wound must be treated as an individual with regard to cause, chronicity, location, and level of microbial contamination, as well as patient factors that affect wound healing. Knowledge of wound care products available and when negative pressure wound therapy and drain placement is appropriate can improve outcomes with wound healing. Inappropriate product use can cause delays in healing. As a wound healing progresses, management of a wound and the bandage material used must evolve. PMID:26022525

  1. Wound Care.

    Science.gov (United States)

    Balsa, Ingrid M; Culp, William T N

    2015-09-01

    Wound care requires an understanding of normal wound healing, causes of delays of wound healing, and the management of wounds. Every wound must be treated as an individual with regard to cause, chronicity, location, and level of microbial contamination, as well as patient factors that affect wound healing. Knowledge of wound care products available and when negative pressure wound therapy and drain placement is appropriate can improve outcomes with wound healing. Inappropriate product use can cause delays in healing. As a wound healing progresses, management of a wound and the bandage material used must evolve.

  2. Home Care

    Science.gov (United States)

    ... care is especially useful for persons who need nursing, therapy, or aide services. You may need help if you are dealing with one or more of the following: You have trouble getting around (for example, after a hospital stay or an accident) You have wounds that need to be cleaned, ...

  3. Just caring.

    Science.gov (United States)

    Hussey, Trevor

    2012-01-01

    Social justice is concerned with fair distribution of the benefits and burdens of living together in society. Regarding nursing care, social justice is concerned with who should receive its benefits, how much they should receive, and who should take up the burden of providing and paying for it. A specific thesis is offered: 'Health care, including nursing care, should be distributed on the basis of need, free at the point of use, the cost being born by the community involved.' This thesis is shown to be incompatible with consequentialist (utilitarian) and libertarian approaches to social justice, but reasons are given for rejecting these theories. It is shown that it may be compatible with Rawl's liberal theory of justice and definitely compatible with a version of the teleological (Aristotelian) theory. The thesis is then defended against criticisms concerned with desert and responsibility: that the provident ought not to pay for the improvident, and that those who are responsible for their health do not deserve free care. There are answered by an epistemological argument concerning what we need to know before we can decide what people deserve, and an argument about social cohesion. The conclusion is that the thesis can be offered as a moral principle for a fair society. PMID:22176544

  4. Maternal care

    OpenAIRE

    2001-01-01

    In June 2000 a distinguished group of obstetricians, midwives, general practitioners, and medical statisticians came together to discuss maternal care. Chaired by Professor James Drife from Leeds, discussion ranged over many topics, including: the changing role of the obstetrician, general practitioners, and the increasing status and responsibility of midwives. Other subjects include the induction of labour, obstetric analgesia and anaesthesia, and debates about the place and kind of delivery...

  5. A Preliminary Study on Foraging Habitat of White-napped Crane on Spring in Qixinghe, Heilongjiang Province%黑龙江七星河春季白枕鹤觅食生境初步研究

    Institute of Scientific and Technical Information of China (English)

    徐景海; 赵国辉; 李晓民

    2013-01-01

    White-napped Crane (Grus vipio)is a large wader. Because of habitat loss, its global population is declining and is now endangered. White -napped Crane is listed in CITES Appendix I (which bans all international trade in the species ) is categorized as Endangered in the IUCN Red list, and is also list-ed in the First Category of Protected Birds in China. During April to May 2011, the foraging habitat of White-napped Crane was investigated using GPS and direct observation at Qixinghe National Nature Reserve, Helongjiang Province. 70 plots (1m ×1m) were established for sampling vegetation. Factors of its foraging habitat including vegetation species, height, coverage, density, water depth and human disturbance were measured and analyzed by quadrate sampling and factor analysis methods. Results indicated that Grus vipio mainly foraging in the wetlands which have Carex spp., Calamagrostis angustifolia. The height of these plants was between 40cm to 80cm, the density was higher than 600 plants per square meter, vegetation cover was mainly between 0 and 25%, and the depth of the foraging place water was 5~15cm, the distance of human disturbance was greater than 1500m. Human activity greatly affects Grus vipio foraging. In spring, Grus vipio sometimes foraging in the burns down.%  白枕鹤(Grus vipio)为大型涉禽,由于栖息地丧失,数量减少,已被CITES列为附录I,IUCN红皮书列为全球濒危物种,并被列为国家II级重点保护鸟类;2011年4~5月,笔者在七星河自然保护区对白枕鹤春季觅食地生境进行了调查;采用GPS定位技术和直接观察法对白枕鹤栖息生境进行测定,共获取70个1m×1m的样方,利用样方法和因子测定法测定其春季觅食地植物的类型、高度、盖度、植物密度、水深、人为干扰距离等。结果显示:白枕鹤春季主要在以苔草、小叶章为主的沼泽湿地中觅食;最佳觅食地植被高度为40~80cm,植被密度高于600株/m2,植被盖度为0

  6. 45 CFR 1306.35 - Family child care program option.

    Science.gov (United States)

    2010-10-01

    ... provider needs to use the bathroom or an infant is napping in one room while toddlers play in another room... alternate providers or the availability of substitute providers. Parents must be informed that they may...

  7. HYDROTHERMAL SYNTHESIS AND CHARACTERIZATION OF NAP1 ZEOLITE AND GISOMDINE FROM SLUDGE INCINERATION ASH%污泥焚烧残渣水热合成NaPl型沸石和水钙沸石的性质研究

    Institute of Scientific and Technical Information of China (English)

    陈小亮; 谷麟; 王艳; 朱南文; 楼紫阳

    2011-01-01

    Zeolite is effective in the ammonia removal in waste water treatment process, while the raw materials for the zeolite are limited. In this work, bottom ash from the incineration plant for sewage sludge was applied to produce NaP1 zeolite and Gisomdine by traditional hydrothermal reaction and the index of correlation were characterized. According to the X-ray diffraction, the scanning electron microscopy (SEM) images and the infrared spectroscopy analysis, zeolite NaP1 and Gismondine were predominated in these products with the radial crystal structure and the zeolitic framework structure. The specific surface area and the cation exchange capacity values of the zeolite was 93.8 mZ-g-1 and 126 mmol.100 g-1, with 47 times and 17 times more than that of the sludge before combustion. In addition, the analysis of adsorption isothermal curves of NH4+ was demonstrated that synthesised zeolite had a good potential for ammonia adsorption at 25 ~C, and the maximum quantity for NH4+ removal was 34.9 mg-g-1 ,which also provides an effective way for the utilization of sludge incineration ash.%本文以污泥焚烧残渣为原料,以传统水热合成方法制得NaPl型沸石和水钙沸石,并对其相关指标进行表征.经x射线衍射、扫描电镜和红外光谱测定表明,制得的产物为无其它杂晶生成的NaPl型沸石和水钙沸石,且具有放射束片状晶体形貌和沸石骨架结构.与原污泥焚烧残渣相比,合成沸石的比表面积和阳离子交换容量提高了47倍、17倍,分别达到93.8m^2·g^-1、126mmol·100g^-1.而合成沸石在25℃下对氨氮的吸附等温线结果显示,其氨氮的最大吸附量为34.9mg·g^-1,吸附性能良好.从而本研究也为实现污泥焚烧残渣的再生资源化提供了一条有效途径.

  8. Caring for Multiples

    Science.gov (United States)

    ... labor & premature birth The newborn intensive care unit (NICU) Birth defects & other health conditions Loss & grief Tools & ... Home > Complications & Loss > The newborn intensive care unit (NICU) > Caring for multiples Caring for multiples E-mail ...

  9. Home Care Services

    Science.gov (United States)

    Home care is care that allows a person with special needs stay in their home. It might be for people who are getting ... chronically ill, recovering from surgery, or disabled. Home care services include Personal care, such as help with ...

  10. Who cares!

    Institute of Scientific and Technical Information of China (English)

    老晃

    2013-01-01

    1有人再三怂恿,希望我能吐槽《富春山居图》,务求鞭辟入里,揭露丑恶真相。我舍不得,舍不得浪费纸。好吧,小吐一下。传说,在《富春山居图》开拍之前有心人提醒导演孙健君,剧本有硬伤,得改,例举一三三四……话没说完,孙勃然大怒,"Who cares!"这位目空一切的君王,他什么都不care,所以他花钱砸的那堆玩意儿,根本也不是电影。这就是真相。值得一说的,是此刻红得发紫,摸都摸不得的《小时代》。

  11. Ustálený chod a zkratové poměry v síti 110 kV E.ON napájené z rozvodny 110 kV Sokolnice v roce 2011

    OpenAIRE

    Jandora, Jiří

    2011-01-01

    Při změně zapojení napájecích transformátorů musíme zjistit, jestli napájená distribuční síť tuto změnu dokáže akceptovat a bude plnit stanovené podmínky. Důležité je dodržet rozmezí dovoleného napětí na jednotlivých rozvodnách této sítě, dále musíme zjistit poměry na jednotlivých vedeních. S tím souvisí zatížení vedení, které nesmí překročit svoji mez (přenosová schopnost). Síť je kontrolována na výpadky vybraných vedení (N-1) a zjišťuje se, jestli ostatní vedení nejsou přetížena při převzet...

  12. Palliative wound care: principles of care.

    Science.gov (United States)

    Dale, Barbara; Emmons, Kevin R

    2014-01-01

    Home care nursing occurs in a complex care environment. Nurses working in this setting care for a wide array of individuals who often are sicker and more complex than ever before. The high prevalence of wounds among these individuals requires that home care nurses have a certain level of knowledge to provide excellent care. Many times, individuals with wounds do not have the capacity to heal or are burdened with numerous symptoms affecting quality of life. In these cases, the home care nurse must understand concepts of palliative wound care to alleviate symptoms with the goal of improving quality of life.

  13. Metoda napěťového kontrastu při detekci sekundárních elektronů scintilačním detektorem ve VP SEM

    OpenAIRE

    Jabůrek, Ladislav

    2011-01-01

    Tato diplomová práce se zabývá problematikou elektronového rastrovacího mikroskopu pracujícího při vyšším tlaku v komoře vzorku. Hlavním cílem práce bylo sledování napěťového kontrastu na přechodu PN výkonového transistoru za vhodných pracovních podmínek za pomocí environmentální rastrovacího mikroskopu. Pozorování vzorku bylo umožněno pomocí scintilačního detektoru určeného pro pozorování ve vysokém tlaku. This thesis deals with scanning electron microscope working at higher pressure in t...

  14. Testování jednotek Merging Unit v sestavě s proudovými a napěťovými převodníky

    OpenAIRE

    Ziegler, Jiří

    2016-01-01

    Diplomová práce je zaměřena na testování a návrh testovací sestavy proudových a napěťových převodníků napojených na slučovací jednotku, která poskytuje digitalizovaný výstup v souladu s IEC 61850-9-2. Parametry a charakteristické vlastnosti testovací sestavy jsou stanoveny na základě principu funkce slučovací jednotky a standardů zabývajících se testováním převodníků. Navržená testovací sestava je založena na modulárním systému PXI Express od společnosti National Instruments. Její návrh je pr...

  15. Izolační systém pro synchronní a asynchronní motory pracující na napěťové hladině 18 kV

    OpenAIRE

    Šporcr, Viktor

    2014-01-01

    Bakalářská práce je rozdělena na dvě samostatné části. První část je zaměřena na izolační systém vysokonapěťových točivých strojů impregnovaných vakuově tlakovou impregnací. Stručně popisuje složení jednotlivých komponentů používaných pro sestavování izolačních systémů vzduchem a vodou chlazených točivých strojů. V druhé praktické části je vyhodnocena dielektrická odolnost sady cívek s izolačním systémem navrženým pro napěťovou hladinu 18 kV. Tato část uvádí stručný popis použitých izolací. D...

  16. Nabíječka NiCd, NiMH a Li-ion akumulátorů napájená a řízená pomocí USB

    OpenAIRE

    Nosek, Petr

    2010-01-01

    Práce se zabývá rozborem a nabíjení baterií typu NiCd, NiMH, Li-lon pomocí mikrokontroleru z řady ATMEL AVR ovládaného a napájeného z PC pomocí USB. Část je věnována charakteristice USB rozhraní a jeho možnostem softwarové enumerace do mikrokontroleru AVR. Obsahuje také základní charakteristiky nabíjených baterií včetně známých metod nabíjení. Druhá polovina práce potom obsahuje kompletní návrh a realizaci nabíječy akumulátorů, která se skládá z elektronické části, porgramu pro mikrokontrolér...

  17. Solární článek jako zdroj napájení pro malý stejnosměrný motor RC modelu auta

    OpenAIRE

    Nábělek, Ondřej

    2009-01-01

    Cílem tohoto projektu je seznámit čtenáře s problematikou solárních článků a návrhu soustavy solárních článků pro napájení elektrického stroje nízkého výkonu. Úvodem je pojednání o energii vyrobené Sluncem dopadající na Zemi. Další kapitola obsahuje informace o principiální funkci solárního křemíkového článku a o přeměně sluneční energie na energii elektrickou. Těžiště práce je věnováno jednotlivým typům solárních článků, výrobním materiálům, struktuře článků a solárním panelům. Poslední část...

  18. Posouzení možnosti připojení nového zdroje z hlediska napěťových poměrů

    OpenAIRE

    Němec, Jan

    2009-01-01

    Připojení nových zdrojů elektrické energie do sítě je důležité pro stávající síť z důvodu její zatížitelnosti a dimenzování. Je třeba zhodnotit, zda možnost připojení nového zdroje do sítě je reálná a neohrožující plynulý chod distribuční soustavy. Tato práce má ukázat jaké podmínky je potřeba splnit pro připojení zdroje do distribuční sítě. A to hlavně z hlediska napěťových poměrů, dále se musí uvažovat působení harmonických proudů a ovlivnění signálu HDO. Na pozadí posuzování připojení zdro...

  19. Zavedení principů štíhlé výroby do výroby komponent pro plynem izolované rozvodny velmi vysokého napětí (GIS)

    OpenAIRE

    Franc, Aleš

    2014-01-01

    Tato diplomová práce je zaměřena na zavádění metod štíhlé výroby. Počátek se věnuje její historii a teoretickému popisu nástrojů. Další část pojednává o společnosti ABB a plynem izolovaných rozvodnách velmi vysokého napětí. Následuje rozbor procesního toku před a po stěhování firmy. V práci je popsána montáž a výrobkové portfolio. Poslední kapitoly se zabývají aplikací metod štíhlé výroby a ekonomickým zhodnocením. This master’s thesis is focused on implementation of lean manufacturing met...

  20. Careful science?

    DEFF Research Database (Denmark)

    Jespersen, Astrid P; Bønnelycke, Julie; Eriksen, Hanne Hellerup

    2014-01-01

    Concern about obesity has prompted numerous public health campaigns that urge people to be more physically active. The campaigns often include normative statements and attempt to impose restrictions on individuals' lives without considering the complexities of daily life. We suggest that broadening...... the focus to reflect everyday practices would foster better targeted public health campaigns. This article is based on our participation in FINE, a multidisciplinary Danish research project. The core methodology of FINE was a randomised controlled trial in which 61 moderately overweight men were put...... into different exercise groups. In this article we analyse the scientific work of the trial as representing entangled processes of bodywork, where data are extracted and objectified bodies are manipulated and care practices address the emotional, social and mundane aspects of the participants' everyday lives...

  1. Perioperative Care of Prisoners: Providing Safe Care.

    Science.gov (United States)

    Smith, Francis Duval

    2016-03-01

    Correctional nurses are trained to care for prisoners in a controlled security environment; however, when a convict is transferred to a noncorrectional health care facility, the nurses there are often unfamiliar with custody requirements or how to safely care for these patients. The care of prisoners outside of prison has not been adequately investigated, and a gap exists between research and nursing education and practice. Nurses rarely have to consider how providing care for a prisoner in custody affects their practice, the potential dissonance between routine nursing care and the requirements to maintain security, or that care of prisoners in unsecured clinical areas places the nurse and other personnel at risk for physical assault or prisoner escape. Educating perioperative nurses in the care of prisoners in a public hospital environment is important for the provision of safe care and prevention of physical and emotional repercussions to personnel.

  2. The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile.

    Directory of Open Access Journals (Sweden)

    Glen P Carter

    2011-10-01

    Full Text Available Nosocomial infections are increasingly being recognised as a major patient safety issue. The modern hospital environment and associated health care practices have provided a niche for the rapid evolution of microbial pathogens that are well adapted to surviving and proliferating in this setting, after which they can infect susceptible patients. This is clearly the case for bacterial pathogens such as Methicillin Resistant Staphylococcus aureus (MRSA and Vancomycin Resistant Enterococcus (VRE species, both of which have acquired resistance to antimicrobial agents as well as enhanced survival and virulence properties that present serious therapeutic dilemmas for treating physicians. It has recently become apparent that the spore-forming bacterium Clostridium difficile also falls within this category. Since 2000, there has been a striking increase in C. difficile nosocomial infections worldwide, predominantly due to the emergence of epidemic or hypervirulent isolates that appear to possess extended antibiotic resistance and virulence properties. Various hypotheses have been proposed for the emergence of these strains, and for their persistence and increased virulence, but supportive experimental data are lacking. Here we describe a genetic approach using isogenic strains to identify a factor linked to the development of hypervirulence in C. difficile. This study provides evidence that a naturally occurring mutation in a negative regulator of toxin production, the anti-sigma factor TcdC, is an important factor in the development of hypervirulence in epidemic C. difficile isolates, presumably because the mutation leads to significantly increased toxin production, a contentious hypothesis until now. These results have important implications for C. difficile pathogenesis and virulence since they suggest that strains carrying a similar mutation have the inherent potential to develop a hypervirulent phenotype.

  3. Health care operations management

    OpenAIRE

    Carter, M W; Hans, E.W.; Kolisch, R.

    2012-01-01

    Health care operations management has become a major topic for health care service providers and society. Operations research already has and further will make considerable contributions for the effective and efficient delivery of health care services. This special issue collects seven carefully selected papers dealing with optimization and decision analysis problems in the field of health care operations management.

  4. Research on Pre-reproduction behavior of White-napped in Qi xinghe Wetland%七星河湿地白枕鹤繁殖前期行为研究

    Institute of Scientific and Technical Information of China (English)

    赵国辉; 李晓民

    2012-01-01

      2012年4月15日~25日在七星河湿地对白枕鹤的繁殖前期行为规律进行了观察.繁殖前期的时间分配中觅食行为43.55%,警戒行为15.18%,游走行为13.79%,理羽行为12.20%,静栖行为11.81%,求偶行为2.48%,其余行为比较少;日节律显示:觅食行为在一天中出现三次高峰,即6:00~7:00、11:00~13:00和14:00~16:00;警戒行为和静栖行为则有一定程度的相似,分别在13:00和14:00左右,达到峰值;游走行为在下午达到低谷,在其他时间趋于稳定;理羽行为在一天中基本趋于稳定.求偶行为只出现在早晨和傍晚之间有两个间断峰值,无规律性.雌雄白枕鹤在理羽行为(p=0.018)和求偶行为(p=0.001)时间分配上存在显著性差异.其余行为时间分配上不存在显著性差异.%  The rhythm of behaviors of White-napped Crane in pre-reproductive period was observed at April 15~25, 2012 in Qi xinghe Wetland. The time budget of various behaviors in pre-re-productive stage was feeding (43.55%), alert (15.18%), walking (13.79%), preening (12.20%), resting (11.81% ), courtship (2.48%), and the else behaviors was rare. The behavior rhythm of White-napped Crane showed that feeding in one day appeared three peaks at 6:00~7:00, 11:00~13:00 and 14:00~16:00. Alert and resting were similar in the certain degree, respectively reached the peak at 13:00 and 14:00. Walking reached the trough at pm and then kept steady in other times. Preening tended to keep steady in a day. Courtship only had two discontinuous peaks and non-regularity. Significant difference was found for female and male between preening (p=0.018) and courtship (p=0.001). There was no significant difference in else behaviors.

  5. Adoption & Foster Care

    Science.gov (United States)

    ... Children > Family Life > Family Dynamics > Adoption & Foster Care Adoption & Foster Care Article Body ​Each year, many children join families through adoption and foster care. These families may face unique ...

  6. About Critical Care Nursing

    Science.gov (United States)

    ... requiring intense and vigilant nursing care. Number of Critical Care Nurses in the United States According to "The Registered ... nurses who work in a hospital setting. Where Critical Care Nurses Work According to "The Registered Nurse Population" study, ...

  7. Oncology and palliative care

    OpenAIRE

    Bausewein, Claudia; Hartenstein, R.

    2000-01-01

    Oncology developed as a discipline over the last decades. Treatment is concentrated on cure or palliation of the illness with the help of chemotherapy, radiotherapy or surgery. Palliative care has its origin in the hospice movement that started around 1960 in the UK. Centre of care is the patient and his family. Focus of care has moved from quantity to quality of life. Symptom control, communication, rehabilitation and care for the dying are main areas of palliative care. Palliative care and ...

  8. Critical care during epidemics

    OpenAIRE

    Rubinson, Lewis; O'Toole, Tara

    2005-01-01

    We recommend several actions that could improve hospitals' abilities to deliver critical care during epidemics involving large numbers of victims. In the absence of careful pre-event planning, demand for critical care services may quickly exceed available intensive care unit (ICU) staff, beds and equipment, leaving the bulk of the infected populace without benefit of potentially lifesaving critical care. The toll of death may be inversely proportional to the ability to augment critical care c...

  9. Integrating palliative care into comprehensive cancer care.

    Science.gov (United States)

    Abrahm, Janet L

    2012-10-01

    While there are operational, financial, and workforce barriers to integrating oncology with palliative care, part of the problem lies in ourselves, not in our systems. First, there is oncologists' "learned helplessness" from years of practice without effective medications to manage symptoms or training in how to handle the tough communication challenges every oncologist faces. Unless they and the fellows they train have had the opportunity to work with a palliative care team, they are unlikely to be fully aware of what palliative care has to offer to their patients at the time of diagnosis, during active therapy, or after developing advanced disease, or may believe that, "I already do that." The second barrier to better integration is the compassion fatigue many oncologists develop from caring for so many years for patients who, despite the oncologists' best efforts, suffer and die. The cumulative grief oncologists experience may go unnamed and unacknowledged, contributing to this compassion fatigue and burnout, both of which inhibit the integration of oncology and palliative care. Solutions include training fellows and practicing oncologists in palliative care skills (eg, in symptom management, psychological disorders, communication), preventing and treating compassion fatigue, and enhancing collaboration with palliative care specialists in caring for patients with refractory distress at any stage of disease. As more oncologists develop these skills, process their grief, and recognize the breadth of additional expertise offered by their palliative care colleagues, palliative care will become integrated into comprehensive cancer care. PMID:23054873

  10. Models of Comprehensive Care

    Science.gov (United States)

    The second plenary of the EPEC-O (Education in Palliative and End-of-Life Care for Oncology) Self-Study: Cultural Considerations When Caring for African Americans reviews the various models for integration of hospice and palliative care into traditional cancer care that have been shown to improve outcomes.

  11. Pediatric Palliative Care

    OpenAIRE

    Johnston, Donna L.; Hentz, Tracy A.; Friedman, Debra L.

    2005-01-01

    Pediatric palliative care provides benefit to children living with life-threatening or terminal conditions. Palliative care should be available to all seriously ill children. Palliative care includes the treatment of symptoms such as pain, nausea, dyspnea, constipation, anorexia, and sialorrhea. This care can occur in a variety of settings, from home to hospice to hospital, and must include bereavement care and follow up after the death of a child. There are many challenges in pediatric palli...

  12. Care for the Health Care Provider.

    Science.gov (United States)

    Kunin, Sharon Brown; Kanze, David Mitchell

    2016-03-01

    Pretravel care for the health care provider begins with an inventory, including the destination, length of stay, logistical arrangements, type of lodging, food and water supply, team members, personal medical needs, and the needs of the community to be treated. This inventory should be created and processed well in advance of the planned medical excursion. The key thing to remember in one's planning is to be a health care provider during one's global health care travel and not to become a patient oneself. This article will help demonstrate the medical requirements and recommendations for such planning. PMID:26900113

  13. Kidney stones - self-care

    Science.gov (United States)

    Renal calculi - self-care; Nephrolithiasis - self-care; Stones - kidney - self-care ... You visited your health care provider or the hospital because you have a kidney stone. You will need to take self-care steps. Which steps ...

  14. 全睡眠剥夺30小时后不同时长恢复性小睡对青年男性睡眠惯性的影响%Effects of sleep inertia on cognitive performance following different time course naps after 30 hours sleep deprivation in healthy men

    Institute of Scientific and Technical Information of China (English)

    常大川; 王文昭; 贺斌; 赵忠新; 包旭芳; 郑良成; 张鹏; 张琳; 李雁鹏; 吴惠涓; 庄建华

    2012-01-01

    course sleeps on sleep stages and cognitions in healthy men after 30 h sleep deprivation,and also to investigate the mechanism of cognitive functions impairment in sleep inertia stages and the influential factors of sleep inertia.Methods Ten healthy men (age,(20.8 ±2.1) years) participated in the program.The program was divided into 2 stages.First,participants attended a series of tests after 20 min nap(20 min nap group)after 30 h sleep deprivation.The testing series included 3 parts:the continuous performance task,the Stroop Tests,and the Addition Tests.The series of tests were done 3 times immediately after the volunteers were awoken and each lasted about 15 minutes with an interval of 10 minutes between each test.The polysomnogram (PSG) was recorded during the nap.The following 7 days was set as washing-out period to ensure a complete recovery.Participants repeated the similar processes with 2 h nap(2 h nap group) instead of 20 min nap.The cognitive performance of each group was compared with each other along with the best cognitive performance in awakening to estimate whether or not the cognitive abilities regained the normal condition.Results ( 1 ) Sleep latency became shortened in both groups after 30 h sleep deprivation.There were no slow wave sleep (SWS) and rapid eye movement sleep (REM) sleep stages in the 20 min naps,while the percentage of SWS was increased and percentage of REM declined in 2 h naps.(2)In the early of SI (5 min after awaking),cognitive tasks showed that the abilities of continuous attention,selected attention and addition ability were all impaired (continuous performance task:(371.8 ± 21.3 ) times/3 min vs (334.4 ± 22.4) times/3 min,( 373.2 ± 19.0) times/3 min vs ( 323.7 ± 23.8) times/3 min,t =10.443,7.774,both P<0.01; Stroop tests:(20.3 ±1.5) points vs(17.3 ± 1.0) points,(21.5 ±0.8)points vs( 16.1 ± 1.4 ) points,t =8.478,4.934,both P < 0.05 ; Addition Tests:( 222.2 ± 13.2 ) s vs ( 266.6 ±23.7 ) s,( 226.3 ± 10.9) s vs ( 267

  15. Research in cardiovascular care

    DEFF Research Database (Denmark)

    Jaarsma, Tiny; Deaton, Christi; Fitzsimmons, Donna;

    2014-01-01

    To deliver optimal patient care, evidence-based care is advocated and research is needed to support health care staff of all disciplines in deciding which options to use in their daily practice. Due to the increasing complexity of cardiac care across the life span of patients combined...... of the body of knowledge that is needed to further improve cardiovascular care. In this paper, knowledge gaps in current research related to cardiovascular patient care are identified, upcoming challenges are explored and recommendations for future research are given....

  16. care about还是care for?

    Institute of Scientific and Technical Information of China (English)

    曾克辉

    2015-01-01

    1问care about和care for可以相互替换使用吗?答:有时可以。但在不同情况下,它们在较确切的含义上还是有区别的。1在表示"喜欢,关心,担心"时,意思一样,常可以互换使用。如:I care about/for your integrity and honesty.我喜欢你的正直和诚实。She doesn’t care about/for politics.她不关心政治。You needn't care about/for his safety.你不必为他的安全担心。2在表示"介意,计较,在乎"等意思时,

  17. Nap sleep spindle correlates of intelligence

    OpenAIRE

    Ujma, Péter P.; Róbert Bódizs; Ferenc Gombos; Johannes Stintzing; Konrad, Boris N.; Lisa Genzel; Axel Steiger; Martin Dresler

    2015-01-01

    Sleep spindles are thalamocortical oscillations in non-rapid eye movement (NREM) sleep, that play an important role in sleep-related neuroplasticity and offline information processing. Several studies with full-night sleep recordings have reported a positive association between sleep spindles and fluid intelligence scores, however more recently it has been shown that only few sleep spindle measures correlate with intelligence in females, and none in males. Sleep spindle regulation underlies a...

  18. Don't be Caught Napping!

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    During the last decade,there has been an increasing number of foreigners coming to China for business,temporary work,study and travel.Most of these visitors are not aware of the so-called“Visitor's Temporary Residence Registration” as required by the municipal Department of Public Safety.The “Visitor's Temporary Residence Registration"”stipulates that either Chinese or foreign citizens must register their temporary residence in a local Department of Public Safety if he or she is only staying temporarily,regardless of the length of saty.

  19. Nap sleep spindle correlates of intelligence

    NARCIS (Netherlands)

    Ujma, P.P.; Bodizs, R.; Gombos, F.; Stintzing, J.; Konrad, B.N.; Genzel, L.; Steiger, A.; Dresler, M.

    2015-01-01

    Sleep spindles are thalamocortical oscillations in non-rapid eye movement (NREM) sleep, that play an important role in sleep-related neuroplasticity and offline information processing. Several studies with full-night sleep recordings have reported a positive association between sleep spindles and fl

  20. Návrh schématu zajištěného napájení jaderného bloku pro řešení projektových i nadprojektových havárií

    OpenAIRE

    Žák, Tomáš

    2013-01-01

    Tato diplomová práce si dává za cíl navržení evolučního schématu zajištěného napájení u jaderných elektráren s reaktory typu VVER 440 při projektových i nadprojektových haváriích. V úvodních kapitolách se tato práce zaměřuje zejména na vymezení pojmů v oblasti hloubkové ochrany jaderného reaktoru, provozních režimů bloku, stejně jako i typy a možnosti elektrického napájení, elektrická schémata bloku. I když je práce zaměřena obecně na VVER 440, je v ní kladen zvláštní důraz na lokalitu Dukova...

  1. Ustálený chod a zkratové poměry v síti 110 kV E.ON napájené z rozvodny 110 kV Otrokovice v roce 2011

    OpenAIRE

    Jurča, Ondřej

    2011-01-01

    Distribuční síť 110 kV společnosti E.ON v oblasti napájené z rozvodny 110 kV Otrokovice je provozována ve dvou variantách zapojení. První varianta je zapojení základní bez můstku. Varianta druhá je pak zapojení s můstkem. Cílem této práce je porovnat na základě výpočtu ustáleného chodu sítě a zkratových poměrů v síti tyto dvě varianty zapojení. Práce je rozdělena do dvou částí, teoretické a praktické. Teoretická část sestává z popisu výpočtu ustáleného chodu sítí velmi vysokého napětí a výpoč...

  2. Elder care - resources

    Science.gov (United States)

    Resources - elder care ... The following organizations are good resources for information on aging and elder care: Administration on Aging -- www.aoa.gov Eldercare Locator -- www.eldercare.gov National Institute on ...

  3. Day Care Centers

    Data.gov (United States)

    Department of Homeland Security — This database contains locations of day care centers for 50 states and Washington D.C. and Puerto Rico. The dataset only includes center based day care locations...

  4. Palliative Care in Cancer

    Science.gov (United States)

    ... care that is given to a person when cancer therapies are no longer controlling the disease. It focuses on caring, not curing. When a person has a terminal diagnosis (usually defined as having a life expectancy ...

  5. US EPA CARE Grants

    Data.gov (United States)

    U.S. Environmental Protection Agency — This is a provisional dataset that contains point locations for the subset of Community Action for a Renewed Environment (CARE) grants given out by the US EPA. CARE...

  6. Critical Care Team

    Science.gov (United States)

    ... of these areas: Surgery Internal medicine Pediatrics Anesthesiology Critical care nurse: A highly skilled nurse who provides all aspects ... and can often uphold the patient's wishes. The critical care nurse becomes an important part of decision-making with ...

  7. Wound Care: Preventing Infection

    Science.gov (United States)

    ... happening, the better you’ll be prepared to take care of yourself once you leave the hospital. You ... skin. If you catch a problem early and take care, you will often be able to continue to ...

  8. Caring for the Caregiver

    Science.gov (United States)

    ... But during this time, it’s important that caregivers take care of themselves too. PDF Kindle ePub This booklet ... cancer This booklet is not about how to take care of a patient. Instead, it mainly provides ways ...

  9. Children's hospice care.

    Science.gov (United States)

    Armstrong-Dailey, A

    1990-01-01

    Facing the inevitable death of a child is a difficult reality for many parents and health care providers as well. Children's Hospice International offers a variety of information and education services to support the provision of children's hospice care.

  10. National Health Care Survey

    Science.gov (United States)

    This survey encompasses a family of health care provider surveys, including information about the facilities that supply health care, the services rendered, and the characteristics of the patients served.

  11. What is palliative care?

    Science.gov (United States)

    ... Living Wills: A Guide to Advance Directives, the Health Care Power of Attorney, and Other Key Documents . Cambridge, MA: Harvard Health Publications. 2013. Oxenham D. Palliative care and pain. ...

  12. Preeclampsia - self-care

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000606.htm Preeclampsia - self-care To use the sharing features on this ... have frequent checkups and tests. Bed Rest and Self-care at Home When you are at home, ...

  13. Diabetes - eye care

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000078.htm Diabetes - eye care To use the sharing features on this ... enable JavaScript. Diabetic retinopathy - care Diabetes and your eyes Diabetes can harm your eyes. It can damage ...

  14. Surgical Critical Care Initiative

    Data.gov (United States)

    Federal Laboratory Consortium — The Surgical Critical Care Initiative (SC2i) is a USU research program established in October 2013 to develop, translate, and validate biology-driven critical care....

  15. Managed care demands flexibility, creativity.

    Science.gov (United States)

    1996-05-01

    The definition of hospice care is changing as home care providers come under managed care regulations. Hospice care for AIDS patients is demanding, requiring extra time from home care providers. The managed care cost-cutting measures require creativitity and patience. The Visiting Nurses and Hospice of San Francisco (VNH) has held seminars to help providers adapt to managed care.

  16. Parental Care and Investment

    OpenAIRE

    González-Voyer, Alejandro; Kolm, N.

    2010-01-01

    Parental care is common throughout the animal kingdom and among caring species there is a bewildering variation in how parents care for offspring, as well as in the amount of resources parents invest in care. For instance, there is considerable variation in the relative parental investment by the sexes – in some species females invest more, in others males invest more, and in some investment is more or less equally shared. Different hypotheses have been proposed to explain patterns of parenta...

  17. Value of care - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Value of care displays – national data. This data set includes national-level data for the value of care displays associated with a 30-day episode of care for...

  18. Enlarged prostate - after care

    Science.gov (United States)

    ... self-care; Benign prostatic hypertrophy - self-care; Benign prostatic hyperplasia - self-care ... Kaplan SA. Benign prostatic hyperplasia and prostatis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap ...

  19. Speak Up: Help Prevent Errors in Your Care: Ambulatory Care

    Science.gov (United States)

    ... role in making health care safe. That includes doctors, nurses and other health care professionals. Health care organizations ... embarrassed if you don't understand what your doctor, nurse or other health care professional tells you. • Don’ ...

  20. Finnish care integrated?

    Directory of Open Access Journals (Sweden)

    Jouni Niskanen

    2002-06-01

    Full Text Available The public Finnish social and health care system has been challenged by the economic crisis, administrative reforms and increased demands. Better integration as a solution includes many examples, which have been taken to use. The most important are the rewritten national and municipals strategies and quality recommendations, where the different sectors and the levels of care are seen as one entity. Many reorganisations have taken place, both nationally and locally, and welfare clusters have been established. The best examples of integrated care are the forms of teamwork, care management, emphasis on non-institutional care and the information technology.

  1. At what cost care?

    Science.gov (United States)

    Pitman, J; Warelow, P J

    2000-03-01

    This paper looks at the concept of care in nursing and considers the ever-changing focus relative to the meaning of the term care and how this care is delivered by nursing staff. In the process of looking at these issues it examines the theoretical and practical issues and how these factors have changed considerably over the last twenty-five years. This examination touches upon some of the intermingled and not mutually exclusive issues which surround care and caring such as technology, stress and burnout, bureaucracy, fiscal policy, the humanness of the nurse and the ever changing nature of care delivery. Many readers will be able to relate to the issues discussed and understand how some of these factors tend to get in the way of one another and affect good patient care and outcomes. PMID:11141767

  2. Does Care Matter?

    DEFF Research Database (Denmark)

    Loft, Lisbeth Trille Gylling; Hogan, Dennis P.

    2014-01-01

    employment during the first 36 weeks following a birth, and its association with experienced non-parental child care use before labor force entry. Using data from the Early Childhood Longitudinal Survey – Birth Cohort (N = 10,400 mothers), results from discrete-time hazard models show that use of non-parental...... for care. The American setting is an ideal context to investigate the linkages between child care capital and maternal employment as the patterns of child care use tend to be more diverse compared to other national context. In the presented application of care capital, we examine mothers’ entry to paid...... child care prior to employment is independently and positively associated with the timing of maternal employment entry. This finding applies both to first-time mothers (n = 3,800) and to mothers of multiple children (n = 6,600). Although data currently available for investigating child care capital...

  3. Neuroeconomics and Integrated Care

    DEFF Research Database (Denmark)

    Larsen, Torben

    2012-01-01

    Background: Fragmented specialized care for the frail elderly as claimed by WHO needs horizontal integration across settings. The home of the patient seems to be a promising place to integrate hospital care, primary care and social services for high-risk discharges where the quality...... of rehabilitation makes a difference. Objective: The study aims to reveal how integrated home care may be organised to improve quality of care as compared to usual hospital care. Method: A qualitative case study of the use of a neuroeconomic model in relation to multidisciplianry collaboration on a RCT...... of integrated home care for stroke patients. Results: (1) The classical understanding of CNS is that of a dual system of ANS and Cortex. The new neuroeconomic understanding is that of a reciprocal balance of Limbic System (LS) and Neocortex (NC). This applies directly in favour of integrated homecare compared...

  4. Acute care nurses' spiritual care practices.

    Science.gov (United States)

    Gallison, Barry S; Xu, Yan; Jurgens, Corrine Y; Boyle, Suzanne M

    2013-06-01

    The purpose of this study was to identify barriers in providing spiritual care to hospitalized patients. A convenience sample (N = 271) was recruited at an academic medical center in New York City for an exploratory, descriptive questionnaire. The Spiritual Care Practice (SCP) questionnaire assesses spiritual care practices and perceived barriers to spiritual care. The SCP determines the percentage that provides spiritual support and perceived barriers inhibiting spiritual care. The participation rate was 44.3% (N = 120). Most (61%) scored less than the ideal mean on the SCP. Although 96% (N = 114) believe addressing patients spiritual needs are within their role, nearly half (48%) report rarely participating in spiritual practices. The greatest perceived barriers were belief that patient's spirituality is private, insufficient time, difficulty distinguishing proselytizing from spiritual care, and difficulty meeting needs when spiritual beliefs were different from their own. Although nurses identify themselves as spiritual, results indicate spirituality assessments are inadequate. Addressing barriers will provide nurses opportunities to address spirituality. Education is warranted to improve nurses' awareness of the diversity of our society to better meet the spiritual needs of patients. Understanding these needs provide the nurse with opportunities to address spirituality and connect desires with actions to strengthen communication and the nurse-patient relationship.

  5. Timely and Effective Care - State

    Data.gov (United States)

    U.S. Department of Health & Human Services — Timely and Effective Care measures - state data. This data set includes state-level data for measures of heart attack care, heart failure care, pneumonia care,...

  6. Genital herpes - self-care

    Science.gov (United States)

    Herpes - genital -self-care; Herpes simplex - genital - self-care; Herpesvirus 2 - self-care; HSV-2 - self-care ... yourself healthy can also minimize the risk of future outbreaks. Things you can do include: Get plenty ...

  7. Broken toe - self-care

    Science.gov (United States)

    Fractured toe - self-care; Broken bone - toe - self-care; Fracture - toe - self-care; Fracture phalanx - toe ... often treated without surgery and can be taken care of at home. Severe injuries include: Breaks that ...

  8. [Primary care in France].

    Science.gov (United States)

    Sánchez-Sagrado, T

    2016-01-01

    The poor planning of health care professionals in Spain has led to an exodus of doctors leaving the country. France is one of the chosen countries for Spanish doctors to develop their professional career. The French health care system belongs to the Bismarck model. In this model, health care system is financed jointly by workers and employers through payroll deduction. The right to health care is linked to the job, and provision of services is done by sickness-funds controlled by the Government. Primary care in France is quite different from Spanish primary care. General practitioners are independent workers who have the right to set up a practice anywhere in France. This lack of regulation has generated a great problem of "medical desertification" with problems of health care access and inequalities in health. French doctors do not want to work in rural areas or outside cities because "they are not value for money". Medical salary is linked to professional activity. The role of doctors is to give punctual care. Team work team does not exist, and coordination between primary and secondary care is lacking. Access to diagnostic tests, hospitals and specialists is unlimited. Duplicity of services, adverse events and inefficiencies are the norm. Patients can freely choose their doctor, and they have a co-payment for visits and hospital care settings. Two years training is required to become a general practitioner. After that, continuing medical education is compulsory, but it is not regulated. Although the French medical Health System was named by the WHO in 2000 as the best health care system in the world, is it not that good. While primary care in Spain has room for improvement, there is a long way for France to be like Spain. PMID:26304179

  9. Patient-centered Care.

    Science.gov (United States)

    Reynolds, April

    2009-01-01

    Patient-centered care focuses on the patient and the individual's particular health care needs. The goal of patient-centered health care is to empower patients to become active participants in their care. This requires that physicians, radiologic technologists and other health care providers develop good communication skills and address patient needs effectively. Patient-centered care also requires that the health care provider become a patient advocate and strive to provide care that not only is effective but also safe. For radiologic technologists, patient-centered care encompasses principles such as the as low as reasonably achievable (ALARA) concept and contrast media safety. Patient-centered care is associated with a higher rate of patient satisfaction, adherence to suggested lifestyle changes and prescribed treatment, better outcomes and more cost-effective care. This article is a Directed Reading. Your access to Directed Reading quizzes for continuing education credit is determined by your area of interest. For access to other quizzes, go to www.asrt.org/store. According to one theory, most patients judge the quality of their healthcare much like they rate an airplane flight. They assume that the airplane is technically viable and is being piloted by competent people. Criteria for judging a particular airline are personal and include aspects like comfort, friendly service and on-time schedules. Similarly, patients judge the standard of their healthcare on nontechnical aspects, such as a healthcare practitioner's communication and "soft skills." Most are unable to evaluate a practitioner's level of technical skill or training, so the qualities they can assess become of the utmost importance in satisfying patients and providing patient-centered care.(1). PMID:19901351

  10. Music in child care

    OpenAIRE

    Maria Polikandrioti; Ioannis Koutelekos

    2007-01-01

    Music has been used therapeutically for many centuries, and numerous studies have researched the curative and preventative powers of music in several diseases. Music, as a therapy was shown to have positive effects in child care, such as in premature infants, children in emergency care, children receiving surgery, children in oncology departments and handicapped children. The aim of this review was to study the therapeutic effects of music in child care at hospital. The method οf this study i...

  11. Italian health care reform

    OpenAIRE

    Livio Garattini

    1992-01-01

    It is remarkable how health care systems, created over decades and influenced by very different cultures exhibit similar problems. Most health care systems are compartmentalised with managers at margins responding to perverse incentives and seeking to shift patients and costs onto rival organisations. Decision makers behave selfishly, considering the welfare of their own organisations rather than those of the health care system as a whole, and in the absence if evidence about the cost-effecti...

  12. Health care delivery systems.

    OpenAIRE

    Stevens, F; Zee, J. van der

    2007-01-01

    A health care delivery system is the organized response of a society to the health problems of its inhabitants. Societies choose from alternative health care delivery models and, in doing so, they organize and set goals and priorities in such a way that the actions of different actors are effective, meaningful, and socially accepted. From a sociological point of view, the analysis of health care delivery systems implies recognition of their distinct history over time, their specific values an...

  13. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Maple, Brenda T.; Letsch, Suzanne W.

    1993-01-01

    This regular feature of the journal includes a discussion of each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they allow us to anticipate the direction and magnitude of health care cost changes prior to the avai...

  14. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Maple, Brenda T.; Cowan, Cathy A.

    1992-01-01

    This regular feature of the journal includes a discussion of each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they allow us to anticipate the direction and magnitude of health care cost changes prior to the avai...

  15. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Maple, Brenda T.; Sensenig, Arthur L.

    1994-01-01

    This regular feature of the journal includes a discussion of each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they allow us to anticipate the direction and magnitude of health care cost changes prior to the avai...

  16. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Maple, Brenda T.; Sivarajan, Lekha

    1993-01-01

    This regular feature of the journal includes a discussion of each of the following four topics community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they allow us to anticipate the direction and magnitude of health care cost changes prior to the avail...

  17. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Sensenig, Arthur L.; Heffler, Stephen K.

    1995-01-01

    This regular feature of the journal includes a discussion of each of the following four topics community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they allow us to anticipate the direction and magnitude of health care cost changes prior to the avail...

  18. Health Care Indicators

    OpenAIRE

    Maple, Brenda T.; Cowan, Cathy A.; Donham, Carolyn S.; Letsch, Suzanne W.

    1991-01-01

    This regular feature of the journal includes a section on each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they provide indicators of the direction and magnitude of health care costs prior to the availability of...

  19. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Sensenig, Arthur L.; Heffler, Stephen K.

    1995-01-01

    This regular feature of the journal includes a discussion of each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they allow us to anticipate the direction and magnitude of health care cost changes prior to the avai...

  20. Health Care Indicators

    OpenAIRE

    Cowan, Cathy A.; Donham, Carolyn S.; Letsch, Suzanne W.; Maple, Brenda T.; Lazenby, Helen C.

    1992-01-01

    This regular feature of the journal includes a section on each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they provide indicators of the direction and magnitude of health care costs prior to the availability of...

  1. Pediatric palliative care

    OpenAIRE

    Trapanotto Manuela; Spizzichino Marco; Benini Franca; Ferrante Anna

    2008-01-01

    Abstract The WHO defines pediatric palliative care as the active total care of the child's body, mind and spirit, which also involves giving support to the family. Its purpose is to improve the quality of life of young patients and their families, and in the vast majority of cases the home is the best place to provide such care, but for cultural, affective, educational and organizational reasons, pediatric patients rarely benefit from such an approach. In daily practice, it is clear that pedi...

  2. Integrated and interprofessional care

    Directory of Open Access Journals (Sweden)

    Hugh Barr

    2012-07-01

    Full Text Available No wonder two movements described in such similar terms are so often confused. One strives to knit services together, the other to cultivate collaborative practice amongst their workers.  Dedicated though both of them are to the improvement of health and social care, integrated care falters without engaging the workforce actively as partners in change whilst interprofessional care falters without organisational support. Neither stands alone. Each depends on the other.

  3. The meaning of care dependency as shared by care givers and care recipients : a concept analysis

    NARCIS (Netherlands)

    Boggatz, Thomas; Dijkstra, Ate; Lohrmann, Christa; Dassen, Theo

    2007-01-01

    Aim. This paper is a report of a concept analysis to identify a meaning of care dependency that can be shared by both care givers and care recipients. Background. Care dependency can be perceived from the care recipient's and the care giver's perspective. To allow for comparisons, both sides should

  4. Democracy, caring and competence

    DEFF Research Database (Denmark)

    Broström, Stig; Johannesson, Eva Marianne; Purola, Anna-Maija;

    2015-01-01

    The aim of the study is to explore how Nordic Early Childhood Education and Care policies frame values education in preschools with a special focus on the values of democracy, caring and competence. The study is part of a larger Nordic project, Valueseducation in Nordic preschools: Basis of...... the study. Keywords related with democratic, caring and competence values were selected. The findings reveal different dimensions and meanings of the three value fields, such as democracy as being and/or becoming; care as fulfilment of basic needs and an ethical relationship; and competence values as...

  5. Caring for the caregiver.

    Science.gov (United States)

    2008-01-01

    Caring for the Caregiver is information for persons helping to care for people with cancer. The emphasis is on what caregivers can do to help themselves at this stressful time. Topics included are: Who Is a Caregiver, Your Feelings, Asking For Help, Caring for Yourself, Going With Your Loved One to Medical Visits, Talking With Others, Remember, Other Resources for Caregivers. The information is written on a basic level and it is very suitable for health professionals to share with persons helping to care for family members or friends who have cancer. The National Cancer Institute posted this information on its website last June 29. PMID:19062356

  6. Progressive Care of Obese Patients.

    Science.gov (United States)

    Dambaugh, Lori A; Ecklund, Margaret M

    2016-08-01

    Obese patients have complex needs that complicate their care during hospitalization. These patients often have comorbid conditions, including hypertension, heart failure, obstructive sleep apnea, pressure ulcers, and difficulty with mobility. Obese patients may be well served in the progressive care setting because they may require more intensive nursing care than can be delivered in a general care unit. Progressive care nurses have core competencies that enable them to safely and effectively care for obese patients. A plan of care with interdisciplinary collaboration illustrates the integrative care for obese progressive care patients. (Critical Care Nurse 2016; 36[4]:58-63). PMID:27481802

  7. Intelligent, Energy Saving Power Supply and Control System of Hoisting Mine Machine with Compact and Hybrid Drive System / Inteligentne, Energooszczędne Układy Zasilania I Sterowania Górniczych Maszyn Wyciągowych Z Napędem Zintegrowanym Lub Hybrydowym

    Science.gov (United States)

    Szymański, Zygmunt

    2015-03-01

    In the paper present's an analysis of suitableness an application of compact and hybrid drive system in hoisting machine. In the paper presented the review of constructional solutions of hoisting machines drive system, driving with AC and DC motor. In the paper presented conception of modern, energy sparing hoisting machine supply system, composed with compact motor, an supplied with transistor or thyristor converter supply system, and intelligent control system composed with multilevel microprocessor controller. In the paper present's also analysis of suitableness application an selected method of artificial intelligent in hoisting machine control system, automation system, and modern diagnostic system. In the paper one limited to analysis of: fuzzy logic method, genetic algorithms method, and modern neural net II and III generation. That method enables realization of complex control algorithms of hosting machine with insurance of energy sparing exploitation conditions, monitoring of exploitation parameters, and prediction diagnostic of hoisting machine technical state, minimization a number of failure states. In the paper present's a conception of control and diagnostic system of the hoisting machine based on fuzzy logic neural set control. In the chapter presented also a selected control algorithms and results of computer simulations realized for particular mathematical models of hoisting machine. Results of theoretical investigation were partly verified in laboratory and industrial experiments. Przedstawiono analizę celowości wprowadzania, napędów zintegrowanych oraz napędów hybrydowych, do układów napędowych maszyn wyciągowych. Zamieszczono przegląd rozwiązań konstrukcyjnych wybranych hybrydowych oraz zintegrowanych napędów maszyn wyciągowych z silnikami DC i AC. Opisano koncepcję nowoczesnego, energooszczędnego układu zasilania górniczych maszyny wyciągowej, złożonego z silnika zintegrowanego, (tranzystorowego lub tyrystorowego

  8. Effect of Primary Health Care Orientation on Chronic Care Management

    OpenAIRE

    Schmittdiel, Julie A.; Shortell, Stephen M.; Rundall, Thomas G; Bodenheimer, Thomas; SELBY, Joe V.

    2006-01-01

    PURPOSE It has been suggested that the best way to improve chronic illness care is through a redesign of primary care emphasizing comprehensive, coordinated care as espoused by the Chronic Care Model (CCM). This study examined the relationship between primary care orientation and the implementation of the CCM in physician organizations.

  9. Do We Value Caring?

    Science.gov (United States)

    Weissbourd, Richard; Anderson, Trisha Ross

    2016-01-01

    When asked about their child-rearing priorities, parents in the United States are likely to say it's more important to raise children who are caring than to raise high achievers. Schools, too, typically trumpet values such as caring, honesty, and fairness. These values are posted on walls, reiterated in assemblies, and included in mission…

  10. Costs of Emergency Care

    Science.gov (United States)

    ... to care for patients, not fewer, and medical liability reform would help reduce overall costs by reducing ... NewsMediaResources/StatisticsData/Just%202%20booklet.pdf [ii] Report: Accounting for the cost of US health care: A ...

  11. Nail care for newborns

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/001914.htm Nail care for newborns To use the sharing features on ... finger or toe instead of the nail. Baby's nails grow quickly, so you may have to cut the fingernails at least once a week. You may only need ... SG, Bedwell C, Cork MJ. Neonatal skin care and toxicology. In: Eichenfield LF, Frieden IJ, Mathes ...

  12. Alliance in Youth Care

    NARCIS (Netherlands)

    Rothman, Linda; Rijsingen, Rinie van; Pijnenburg, Huub

    2015-01-01

    This article introduces the concept of alliance in youth care. The concept of (therapeutic) alliance originates in adult psychotherapy and related research. Alliance refers to the working relationship between youth care workers and their clients. Within this concept, personal (emotional) and task re

  13. Primary Care's Dim Prognosis

    Science.gov (United States)

    Alper, Philip R.

    2010-01-01

    Given the chorus of approval for primary care emanating from every party to the health reform debate, one might suppose that the future for primary physicians is bright. Yet this is far from certain. And when one looks to history and recognizes that primary care medicine has failed virtually every conceivable market test in recent years, its…

  14. Robots that care

    NARCIS (Netherlands)

    Looije, R.; Arendsen, J.; Saldien, J.; Vanderborght, B.; Broekens, J.; Neerincx, M.

    2010-01-01

    Many countries face pressure on their health care systems. To alleviate this pressure, 'self care' and 'self monitoring' are often stimulated with the use of new assistive technologies. Social robotics is a research area where robotic technology is optimized for various social functions. One of thes

  15. Health Care Waste Management

    OpenAIRE

    World Bank

    2003-01-01

    Health care waste management (HCWM) is a process to help ensure proper hospital hygiene and safety of health care workers and communities. It includes planning and procurement, construction, staff training and behavior, proper use of tools, machines and pharmaceuticals, proper disposal methods inside and outside the hospital, and evaluation. Its many dimensions require a broader focus than ...

  16. Health care marketing management.

    Science.gov (United States)

    Cooper, P D

    1979-01-01

    Health Care Marketing Management is the process of understanding the needs and the wats of a target market. Its purpose is to provide a viewpoint from which to integrate the analysis, planning, implementation (or organization) and control of the health care delivery system.

  17. Health care delivery systems.

    NARCIS (Netherlands)

    Stevens, F.; Zee, J. van der

    2007-01-01

    A health care delivery system is the organized response of a society to the health problems of its inhabitants. Societies choose from alternative health care delivery models and, in doing so, they organize and set goals and priorities in such a way that the actions of different actors are effective,

  18. Finding Health Care Services

    Science.gov (United States)

    If you have been diagnosed with cancer, finding a doctor and treatment facility for your cancer care is an important step to getting the best treatment possible. Learn tips for choosing a doctor and treatment facility to manage your cancer care.

  19. Surgical wound care

    Science.gov (United States)

    ... F for more than 4 hours Alternate Names Surgical incision care; Open wound care Images Proper hand washing References Lynn PB. Cleaning a wound and applying a dry, sterile dressing. In: Lynn PB. Taylor’s Handbook of Nursing Skills . Philadelphia, PA: Lippincott Williams and Wilkins, Wolters ...

  20. The Inquiry of Care

    Science.gov (United States)

    Nelsen, Peter

    2013-01-01

    While discussions of the moral dimensions of the caring relation and their implications for teaching and learning are well developed within the literature, there has not been much analysis of the place of inquiry within our understanding of caring and the education inspired by it. Previous discussions offer important insight into what…

  1. Educating to Care

    Science.gov (United States)

    Mortari, Luigina

    2004-01-01

    The root of the ecological crisis lies in an ethic of nature consumption. In order to reconstruct our cultural framework, it is necessary to cultivate another ethical approach, an ethic of care. It is the responsibility of school to encourage students to learn how to care for not only the human world, but also for the natural world. This paper is…

  2. Prevention IS Care

    Centers for Disease Control (CDC) Podcasts

    2009-03-26

    This podcast provides an overview of the Prevention IS Care campaign, which provides HIV prevention tools for medical care providers to use on a daily basis with patients who are living with HIV.  Created: 3/26/2009 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP).   Date Released: 3/26/2009.

  3. Caring about the young

    NARCIS (Netherlands)

    John Stevens; Evert Pommer; Hetty van Kempen; Elke Zeijl; Isolde Woittiez; Klarita Sadiraj; Rob Gilsing; Saskia Keuzenkamp

    2009-01-01

    Original title: De jeugd een zorg. Youth care services are going through major changes. This has created a need for a better insight into the demand that is likely to be placed on these services in the future at both national and regional level. This report suggests that the use of ambulant care w

  4. Care, Europeanization and Gender

    DEFF Research Database (Denmark)

    Dyrberg, Torben Bech

    This book adresses the recent underexamined developments concerning care in Europe, including the negotiations about care at the top EU level to that of individual workers. Through a comparative and interdisciplinary approach, this collection examines and further develops current theoretical and ...

  5. Child Care Centres.

    Science.gov (United States)

    Australian Dept. of Labour and National Service, Melbourne. Women's Bureau.

    Based on a survey of legislation relating to full-day care for preschool children of working mothers and a study of records, this report: (1) covers the number of registered child care centers in Australia and the number of children being served, (2) sets the conditions applying to registration of centers, (3) indicates the extent and levels of…

  6. Child Care at CERN

    CERN Document Server

    CERN, Child Care Initiative

    2008-01-01

    This is a document summarizing a survey of child care needs of CERN staff and users which was performed in February 2008 by the CERN Child Care Initiative. The document presents the analysis of this data. Conclusions on the minimal facilities size are derived and possible funding source at the European Union are discussed.

  7. Improved wound care product

    DEFF Research Database (Denmark)

    2012-01-01

    The present invention pertains to use of sodium diacetate (NaHAc 2) as an antimicrobial agent against bacteria growing in biofilms. The aspects of the invention include a wound care product comprising sodium diacetate, a kit comprising a wound care product,and a methodof treating an infected wound....

  8. Benchmarking HIV health care

    DEFF Research Database (Denmark)

    Podlekareva, Daria; Reekie, Joanne; Mocroft, Amanda;

    2012-01-01

    ABSTRACT: BACKGROUND: State-of-the-art care involving the utilisation of multiple health care interventions is the basis for an optimal long-term clinical prognosis for HIV-patients. We evaluated health care for HIV-patients based on four key indicators. METHODS: Four indicators of health care were...... assessed: Compliance with current guidelines on initiation of 1) combination antiretroviral therapy (cART), 2) chemoprophylaxis, 3) frequency of laboratory monitoring, and 4) virological response to cART (proportion of patients with HIV-RNA 90% of time on cART). RESULTS: 7097 Euro...... to North, patients from other regions had significantly lower odds of virological response; the difference was most pronounced for East and Argentina (adjusted OR 0.16[95%CI 0.11-0.23, p HIV health care utilization...

  9. Shared care and boundaries:

    DEFF Research Database (Denmark)

    Winthereik, Brit Ross

    2008-01-01

    of responsibilities entailed in shared care projects. Rather than seeking to connect all actors in an unbounded space, shared care might instead suggest a space for patients and professionals to experiment with new roles and responsibilities. Practical implications – When designing coordination tools for health care......Purpose – The paper seeks to examine how an online maternity record involving pregnant women worked as a means to create shared maternity care. Design/methodology/approach – Ethnographic techniques have been used. The paper adopts a theoretical/methodological framework based on science...... and technology studies. Findings – The paper shows how a version of “the responsible patient” emerges from the project which is different from the version envisioned by the project organisation. The emerging one is concerned with the boundary between primary and secondary sector care, and not with the boundary...

  10. Empowering and caring professionals

    DEFF Research Database (Denmark)

    Hansen, Agnete Meldgaard

    care services. The reform programs are put in place to counter the demographic challenges faced by the Nordic (and many other) welfare states, known under the pessimistic expression ‘the burden of ageing’. Based on ethnographic case studies in two Danish municipalities, the paper illustrates how care......A wave of policies to reform municipal elderly care services is sweeping across Denmark. Under headings such as ‘help for self-help’, ‘everyday rehabilitation’, and ‘re-ablement’, municipalities are working to make their elderly citizens more self-reliant, active and less dependent on municipal...... workers negotiate professional identities and understandings of meaningful care work, in the new regime of rehabilitative elderly care – how they manage the ambiguities of a simultaneously empowering and interventionist practice. The paper’s analytical framework draws on an understanding of empowerment...

  11. Orphan Care in China

    Directory of Open Access Journals (Sweden)

    Meng, Liu

    2009-07-01

    Full Text Available Orphan care in China was once provided by the central government as a means of social control. The centralized welfare delivery guaranteed some of the poorest orphans to be protected by the government. Since the economic reform, the central government started to relinquish its control over social welfare delivery, new forms of orphan care were introduced into China, sharing the responsibilities and burdens for caring the orphans. Yet, many issues and problems exist in social delivery due to a lack of finances, professionals, and policy support. In this chapter, we will discuss the background of social welfare changes in China, as pertains to orphan care, focusing on the different types of orphans as a result of social issues, service delivery, barriers and solutions. It is claimed that during the reform, the burden of orphan care in China may not be reduced in the coming future, and we offer suggestions to cope with that.

  12. "Patient care in radiology"

    DEFF Research Database (Denmark)

    Bro Brask, Kirsten; Birkelund, Regner

    2014-01-01

    The aim of this study was to research how the staff experience care expressed during the brief encounter with the patients in a diagnostic imaging department. This was a qualitative study with a phenomenological and hermeneutical frame of reference. The data were collected using field observations...... and semistructured interviews and analyzed according to the guidelines for meaning condensation by Giorgi. The imaging staff found that care is expressed in an administrative, an instrumental, and a compassionate sense. The imaging staff perceived care in a way that clearly differs from the traditional perception...... of care understood as the close relations between people. In their self-understanding, the staff found that care not only comprised the relational aspect but also that it was already delivered during the preparatory phases before the actual meeting with the patient and up until the image...

  13. Becoming Care Helper

    DEFF Research Database (Denmark)

    Jensen, Anne Winther

    The paper discusses the shaping of students´ identity within a vocational education programme for elderly care in Denmark. The focus is on the correlation between identity construction within the theoretical periods and students´ experiences in the traineeships. In the school setting the future...... care helper is being constructed within the overall term ‘professional’, but students may meet differing ways of being care helper in the traineeships, and the paper points to an ongoing struggle about the definition of ‘being care helper’. The analysis of the identity issues mobilises the concepts...... ‘positioning’ and ‘storyline’, c.f. Bronwyn Davies, and the empirical material consists of interviews and observations in the theoretical periods and in the traineeships. The paper suggests that a shift from identity to subjectivity may help students to deal with the diversity of ‘care helpers’ and thereby...

  14. Managed care and economic dynamics.

    Science.gov (United States)

    Riggs, J E

    1996-09-01

    Over the past several decades, health care delivery in the United States evolved in an environment lacking marketplace constraints. The unforeseen result was the current health care crisis--uncontrolled costs, shrinking access, and redundant technological capabilities. Managed care is a strategy to impose fiscal constraints on health care delivery. A diagrammatic analysis of the economic dynamics between consumers and producers in an open marketplace is compared with that of patients, providers, and payers under the health care scheme that produced the health care crisis and under managed care. Patient demands, expectations, and needs for health care are not subject to fiscal constraint under managed care since the dislinkage between consumer and payer still exits. Managed care does not impose true open marketplace fiscal constraints on health care delivery. Furthermore, any solution to the US health care crisis that used true marketplace fiscal constraints would necessitate fundamental changes in societal values concerning individual rights to health care.

  15. Primary care for refugees.

    Science.gov (United States)

    Eckstein, Barbara

    2011-02-15

    Over the past decade, at least 600,000 refugees from more than 60 different countries have been resettled in the United States. The personal history of a refugee is often marked by physical and emotional trauma. Although refugees come from many different countries and cultures, their shared pattern of experiences allows for some generalizations to be made about their health care needs and challenges. Before being accepted for resettlement in the United States, all refugees must pass an overseas medical screening examination, the purpose of which is to identify conditions that could result in ineligibility for admission to the United States. Primary care physicians have the opportunity to care for members of this unique population once they resettle. Refugees present to primary care physicians with a variety of health problems, including musculoskeletal and pain issues, mental and social health problems, infectious diseases, and longstanding undiagnosed chronic illnesses. Important infectious diseases to consider in the symptomatic patient include tuberculosis, parasites, and malaria. Health maintenance and immunizations should also be addressed. Language barriers, cross-cultural medicine issues, and low levels of health literacy provide additional challenges to caring for this population. The purpose of this article is to provide primary care physicians with a guide to some of the common issues that arise when caring for refugee patients.

  16. Caring in telehealth.

    Science.gov (United States)

    Varghese, Shainy B; Phillips, Carolyn A

    2009-12-01

    The overall goal of this study was to explore and describe the perceptions of advanced practice nurses (APNs) about caring while providing primary care using telehealth technology. This study used naturalistic inquiry methodology to elicit the subjective perceptions and reflections of a sample of APNs about how they convey caring in the context of telehealth. Thirteen APNs, selected by purposive and snowball sampling, participated in the study. The data for the study consisted of interviews conducted by e-mail using a semistructured interview guide. Data analysis used the constant comparison method; rigor and trustworthiness of the study procedures were established using the criteria of credibility, confirmability, dependability, and transferability. The findings of this study revealed that the APNs conveyed caring to their telehealth patients by (1) being with them, (2) personifying the images, and (3) possessing certain attributes. The major constructs that emerged from the data together formed a model of how APNs conveyed caring in telehealth. The findings provide insights and increase the understanding of how caring in telehealth was perceived by APNs. The findings of the study can make important contributions in improving our profession's preparation of future telehealth APNs. The study findings also can lend themselves to developing an instrument to measure caring in telehealth. The study findings also contribute to the nursing literature in a number of ways.

  17. Advocacy for eye care

    Directory of Open Access Journals (Sweden)

    Thulasiraj D Ravilla

    2012-01-01

    Full Text Available The effectiveness of eye care service delivery is often dependant on how the different stakeholders are aligned. These stakeholders range from the ministries of health who have the capacity to grant government subsidies for eye care, down to the primary healthcare workers who can be enrolled to screen for basic eye diseases. Advocacy is a tool that can help service providers draw the attention of key stakeholders to a particular area of concern. By enlisting the support, endorsement and participation of a wider circle of players, advocacy can help to improve the penetration and effectiveness of the services provided. There are several factors in the external environmental that influence the eye care services - such as the availability of trained manpower, supply of eye care consumables, government rules and regulations. There are several instances where successful advocacy has helped to create an enabling environment for eye care service delivery. Providing eye care services in developing countries requires the support - either for direct patient care or for support services such as producing trained manpower or for research and dissemination. Such support, in the form of financial or other resources, can be garnered through advocacy.

  18. Pediatric Palliative Care in the Intensive Care Unit.

    Science.gov (United States)

    Madden, Kevin; Wolfe, Joanne; Collura, Christopher

    2015-09-01

    The chronicity of illness that afflicts children in Pediatric Palliative Care and the medical technology that has improved their lifespan and quality of life make prognostication extremely difficult. The uncertainty of prognostication and the available medical technologies make both the neonatal intensive care unit and the pediatric intensive care unit locations where many children will receive Pediatric Palliative Care. Health care providers in the neonatal intensive care unit and pediatric intensive care unit should integrate fundamental Pediatric Palliative Care principles into their everyday practice. PMID:26333755

  19. Primary Care Clinics and Accountable Care Organizations

    Directory of Open Access Journals (Sweden)

    Judith Ortiz PhD

    2015-10-01

    Full Text Available Background: The Accountable Care Organization (ACO is one of the new models of health care delivery in the United States. To date, little is known about the characteristics of health care organizations that have joined ACOs. We report on the findings of a survey of primary care clinics, the objective of which was to investigate the opinions of clinic management about participation in ACOs and the characteristics of clinic organizational structure that may contribute to joining ACOs or be willing to do so. Methods: A 27-item survey questionnaire was developed and distributed by mail in 3 annual waves to all Rural Health Clinics (RHCs in 9 states. Two dependent variables—participation in ACOs and willingness to join ACOs—were created and analyzed using a generalized estimating equation approach. Results: A total of 257 RHCs responded to the survey. A small percentage (5.2% of the respondent clinics reported that they were participating in ACOs. Rural Health Clinics in isolated areas were 78% less likely to be in ACOs (odds ratio = 0.22, P = .059. Nonprofit RHCs indicated a higher willingness to join an ACO than for-profit RHCs (B = 1.271, P = .054. There is a positive relationship between RHC size and willingness to join an ACO (B = 0.402, P = .010. Conclusion: At this early stage of ACO development, many RHC personnel are unfamiliar with the ACO model. Rural providers’ limited technological and human resources, and the lack of ACO development in rural areas, may delay or prevent their participation in ACOs.

  20. Hair care and dyeing.

    Science.gov (United States)

    Draelos, Zoe Diana

    2015-01-01

    Alopecia can be effectively camouflaged or worsened through the use of hair care techniques and dyeing. Proper hair care, involving hair styling and the use of mild shampoos and body-building conditioners, can amplify thinning scalp hair; however, chemical processing, including hair dyeing, permanent waving, and hair straightening, can encourage further hair loss through breakage. Many patients suffering from alopecia attempt to improve their hair through extensive manipulation, which only increases problems. Frequent haircuts to minimize split ends, accompanied by gentle handling of the fragile fibers, is best. This chapter offers the dermatologist insight into hair care recommendations for the alopecia patient.

  1. Hair care and dyeing.

    Science.gov (United States)

    Draelos, Zoe Diana

    2015-01-01

    Alopecia can be effectively camouflaged or worsened through the use of hair care techniques and dyeing. Proper hair care, involving hair styling and the use of mild shampoos and body-building conditioners, can amplify thinning scalp hair; however, chemical processing, including hair dyeing, permanent waving, and hair straightening, can encourage further hair loss through breakage. Many patients suffering from alopecia attempt to improve their hair through extensive manipulation, which only increases problems. Frequent haircuts to minimize split ends, accompanied by gentle handling of the fragile fibers, is best. This chapter offers the dermatologist insight into hair care recommendations for the alopecia patient. PMID:26370650

  2. LEARN TO CARE

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    IN April, the Beijing Education Commission, Beijing Women’s Federation and the China Institute of Family Education jointly decided the theme of China’s family education for 1997: Learn to care and teach good behavior. This theme reminds us of the requirement of young generations in many other countries: Learn to survive, learn to care. It reveals that learning to care about others is not only a problem faced by Chinese children, most of whom grow up as an only child, but is a common problem in children’s education

  3. Health care utilization

    DEFF Research Database (Denmark)

    Jacobsen, Christian Bøtcher; Andersen, Lotte Bøgh; Serritzlew, Søren

    An important task in governing health services is to control costs. The literatures on both costcontainment and supplier induced demand focus on the effects of economic incentives on health care costs, but insights from these literatures have never been integrated. This paper asks how economic cost...... make health professionals provide more of this service to each patient, but that lower user payment (unexpectedly) does not necessarily mean higher total cost or a stronger association between the number of patients per supplier and the health care utilization. This implies that incentives...... are important, but that economics cannot alone explain the differences in health care utilization....

  4. Timely and Effective Care - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Timely and Effective Care measures - national data. This data set includes national-level data for measures of heart attack care, heart failure care, pneumonia...

  5. Timely and Effective Care - Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — Timely and Effective Care measures - provider data. This data set includes provider-level data for measures of heart attack care, heart failure care, pneumonia...

  6. FastStats: Hospice Care

    Science.gov (United States)

    ... Population Sex Men's Health Women's Health State and Territorial Data Reproductive Health Contraceptive Use Infertility Reproductive Health ... Term Care Providers Nursing Home Care Residential Care Communities Centers for Medicare and Medicaid Services Hospice Foundation ...

  7. Choosing Your Prenatal Care Provider

    Science.gov (United States)

    ... care provider is. These kinds of providers can take care of you during pregnancy and deliver your baby: ... doctor who has special education and training to take care of pregnant women and deliver babies. About 8 ...

  8. Care for an Uncircumcised Penis

    Science.gov (United States)

    ... Prenatal Baby Bathing & Skin Care Breastfeeding Crying & Colic Diapers & Clothing Feeding & Nutrition Preemie Sleep Teething & Tooth Care Toddler Preschool Gradeschool Teen Young Adult Healthy Children > Ages & Stages > Baby > Bathing & Skin Care > ...

  9. Identifying health care quality attributes.

    Science.gov (United States)

    Ramsaran-Fowdar, Roshnee R

    2005-01-01

    Evaluating health care quality is important for consumers, health care providers, and society. Developing a measure of health care service quality is an important precursor to systems and organizations that value health care quality. SERVQUAL has been proposed as a broad-based measure of service quality that may be applicable to health care settings. Results from a study described in this paper verify SERVQUAL dimensions, but demonstrate additional dimensions that are specific to health care settings. PMID:16318013

  10. Community-Based Care

    Science.gov (United States)

    ... respite care, transportation, medication coverage, rehabilitation (including maintenance physical and occupational therapy ), hearing aids, eyeglasses, and a variety of other benefits. The program also has the flexibility to pay ...

  11. Home Health Care

    Science.gov (United States)

    ... top Ensuring Quality Care As with any important purchase, it is wise to talk with friends, neighbors, ... dentures, eyeglasses, canes, walkers, hearing aids, etc. Possible behavior problems and how best to handle them Mobility ...

  12. Dental Care in Pregnancy

    Science.gov (United States)

    ... to other parts of the mouth. However, your dentist can treat periodontal disease even when you are ... the teeth. Is it safe to visit your dentist in pregnancy? Dental care is safe during pregnancy ...

  13. Hospice Care in America

    Science.gov (United States)

    ... than 50 patients per year to large, national corporate chains that care for thousands of patients each ... provided to patients and families? Among its major responsibilities, the ... for a social worker. Table 12. Distribution of Paid Staff FTEs  ...

  14. Suprapubic catheter care

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000145.htm Suprapubic catheter care To use the sharing features on this page, please enable JavaScript. A suprapubic catheter (tube) drains urine from your bladder. It is ...

  15. Penis care (uncircumcised)

    Science.gov (United States)

    ... causing swelling and pain (paraphimosis). This needs medical care. ... Elder JS. Anomalies of the penis and urethra. In: Kliegman RM, Stanton ... D, eds. Textbook of Family Medicine . 9th ed. Philadelphia, ...

  16. Skin Care and Aging

    Science.gov (United States)

    ... page please turn Javascript on. Skin Care and Aging How Aging Affects Skin Your skin changes with age. It ... if they bother you. See additional resources on aging skin, including information on treatment options, specific conditions, ...

  17. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Maple, Brenda T.

    1989-01-01

    Contained in this regular feature of the journal is a section on each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; and national economic indicators.

  18. American Health Care Association

    Science.gov (United States)

    ... Testimony AHCA/NCAL PAC Federal Political Directors Political Events Solutions Facility Operations Affordable Care Act Clinical Emergency Preparedness Finance Health Information Technology Integrity Medicaid Medicare Patient Privacy and ...

  19. Respiratory Home Health Care

    Science.gov (United States)

    ... Health Care Font: Aerosol Delivery Oxygen Resources Immunizations Pollution Nutrition Exercise Coming Of Age Older Adults Allergy ... it is so cold it could hurt your skin. Make sure your electrical system doesn’t overload ...

  20. Quotes on Caring

    Science.gov (United States)

    Knowledge Quest, 2012

    2012-01-01

    In this article, school librarians from Henrico County Public Schools in Virginia [the AASL 2011 National School Library Programs of the Year (NSLPY) Award recipient] share some of their experiences caring for students in their libraries.

  1. Affordable Care Act (ACA)

    Data.gov (United States)

    Social Security Administration — The Affordable Care Act (ACA) is a federal statute enacted with a goal of increasing the quality and affordability of health insurance. Through a web service, CMS...

  2. [Palliative care for glioblastoma].

    Science.gov (United States)

    Dieudonné, Nathalie; De Micheli, Rita; Hottinger, Andreas

    2016-04-27

    Patients with glioblastoma have a limited life expectancy and an impaired quality of life and they should be offered palliative care soon after the diagnosis is established. Still, only a quarter of patients aged over 65 return home or medical institution after completing treatments. Home care must be promoted by coordinating assistance and care, combining disciplines such as physiotherapy and ergotherapy, medical and nursing care and psychosocial support. Patients are at risk of mood, personality and behavioural disorders. Limited awareness of these troubles and their physical limitations alter their capacity of rehabilitation and social relationships. Isolation of relatives, exhaustion and misunderstandings should be prevented. The therapeutic goals should be discussed and determined upstream to anticipate difficulties and questions concerning end of life. PMID:27281945

  3. CancerCare

    Science.gov (United States)

    ... Learn more A cancer diagnosis turns a person’s world upside down — emotionally, physically and financially. Cancer Care ® ... Caregiving When Your Loved One Has Triple Negative Breast Cancer Connect Education Workshop Reiki Community Program Oct 27 ...

  4. Skin care and incontinence

    Science.gov (United States)

    Incontinence - skin care ... or bowels (called incontinence) are at risk of skin problems around the buttocks, hips, genitals, and the ... rectum (perineum). Excess moisture in these areas makes skin problems such as redness, peeling, irritation, and yeast ...

  5. Office of Child Care

    Science.gov (United States)

    ... Learn more about the Child Care Rule > OCC Publishes Approved FY 2016-2018 CCDF Plans The Plan ... Instructions Information Memoranda Policy Interpretation Questions Technical Bulletins Administration for Children & Families U.S. Department of Health & Human ...

  6. Resilient health care

    DEFF Research Database (Denmark)

    Hollnagel, E.; Braithwaite, J.; Wears, R. L.

    Health care is everywhere under tremendous pressure with regard to efficiency, safety, and economic viability - to say nothing of having to meet various political agendas - and has responded by eagerly adopting techniques that have been useful in other industries, such as quality management, lean...... production, and high reliability. This has on the whole been met with limited success because health care as a non-trivial and multifaceted system differs significantly from most traditional industries. In order to allow health care systems to perform as expected and required, it is necessary to have...... engineering's unique approach emphasises the usefulness of performance variability, and that successes and failures have the same aetiology. This book contains contributions from acknowledged international experts in health care, organisational studies and patient safety, as well as resilience engineering...

  7. Organizing Rural Health Care

    DEFF Research Database (Denmark)

    Bunkenborg, Mikkel

    2012-01-01

    The liberalization of health care in the course of three decades of ‘reform and opening up’ has given people in rural China access to a diverse range of treatment options, but the health care system has also been marred by accusations of price hikes, fake pharmaceuticals, and medical malpractice....... This chapter offers an ethnographic description of health as an issue in a Hebei township and it focuses on a popular and a statist response to the perceived inadequacy of the rural health care system. The revival of religious practices in rural China is obviously motivated by many factors, but in the township...... roads to healing. The recent introduction of new rural cooperative medicine in the township represents an attempt to bring the state back in and address popular concern with the cost and quality of health care. While superficially reminiscent of the traditional socialist system, this new state attempt...

  8. Moving survivorship care plans forward: focus on care coordination.

    Science.gov (United States)

    Salz, Talya; Baxi, Shrujal

    2016-07-01

    After completing treatment for cancer, the coordination of oncology and primary care presents a challenge for cancer survivors. Many survivors need continued oncology follow-up, and all survivors require primary care. Coordinating the shared care of a cancer survivor, or facilitating an informed handoff from oncology to primary care, is essential for cancer survivors. Survivorship care plans are personalized documents that summarize cancer treatment and outline a plan of recommended ongoing care, with the goal of facilitating the coordination of post-treatment care. Despite their face validity, five trials have failed to demonstrate the effectiveness of survivorship care plans. We posit that these existing trials have critical shortcomings and do not adequately address whether survivorship care plans improve care coordination. Moving forward, we propose four criteria for future trials of survivorship care plans: focusing on high-needs survivor populations, tailoring the survivorship care plan to the care setting, facilitating implementation of the survivorship care plan in clinical practice, and selecting appropriate trial outcomes to assess care coordination. When trials meet these criteria, we can finally assess whether survivorship care plans help cancer survivors receive optimal oncology and primary care.

  9. Helping You Choose Quality Hospice Care

    Science.gov (United States)

    ... Accreditation Accreditation Ambulatory Health Care Behavioral Health Care Critical Access Hospitals Home Care (+ Pharmacy) Hospital Laboratory Nursing Care Center International Accreditation Accreditation Top Spots What ...

  10. Health care reforms

    OpenAIRE

    Marušič Dorjan; Prevolnik Rupel Valentina

    2016-01-01

    In large systems, such as health care, reforms are underway constantly. The article presents a definition of health care reform and factors that influence its success. The factors being discussed range from knowledgeable personnel, the role of involvement of international experts and all stakeholders in the country, the importance of electoral mandate and governmental support, leadership and clear and transparent communication. The goals set need to be clear, and it is helpful to have good da...

  11. Science of Human Caring

    OpenAIRE

    Foss-Durant, Anne M.

    2014-01-01

    Background: When state-mandated ratios were enacted, our leadership team began exploring the care delivery model. Increasing the number of nurses on each unit provided an opportunity to refocus care on the relationship with the patient and family. During the initial phases of this transition work, we engaged frontline staff in dialogue. What surfaced were feelings of being overwhelmed, anxiety about being able to complete everything before the end of the shift, feelings of defeat or illness b...

  12. Teamwork for eye care

    Directory of Open Access Journals (Sweden)

    M Babar Qureshi

    2014-04-01

    Full Text Available Human resource development (HRD – the development of the people who deliver health care – has been identified as one of the key pillars of eye health delivery. HRD is one of the essential building blocks of the World Health Organization (WHO Global Action Plan: ‘Towards universal eye health’. The importance of HRD is also recognised beyond eye care, as can be seen in the WHO Health Systems approach.

  13. Teamwork for eye care

    OpenAIRE

    M Babar Qureshi

    2014-01-01

    Human resource development (HRD) – the development of the people who deliver health care – has been identified as one of the key pillars of eye health delivery. HRD is one of the essential building blocks of the World Health Organization (WHO) Global Action Plan: ‘Towards universal eye health’. The importance of HRD is also recognised beyond eye care, as can be seen in the WHO Health Systems approach.

  14. Mercury and health care

    OpenAIRE

    Rustagi Neeti; Singh Ritesh

    2010-01-01

    Mercury is toxic heavy metal. It has many characteristic features. Health care organizations have used mercury in many forms since time immemorial. The main uses of mercury are in dental amalgam, sphygmomanometers, and thermometers. The mercury once released into the environment can remain for a longer period. Both acute and chronic poisoning can be caused by it. Half of the mercury found in the atmosphere is human generated and health care contributes the substantial part to it. The world ha...

  15. Health Care Indicators

    OpenAIRE

    Cowan, Cathy A.; Letsch, Suzanne W.; Levit, Katharine R.; Maple, Brenda T.; Stewart, Madie W.

    1991-01-01

    This regular feature of the journal includes a section on each of the following four topics: community hospital statistics; employment, hours, and earnings in the private health sector; prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they provide indicators of the direction and magnitude of health care costs prior to the availability of more compre...

  16. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Letsch, Suzanne W.; Maple, Brenda T.; Singer, Naphtale; Cowan, Cathy A.

    1991-01-01

    Contained in this regular feature of the journal is a section on each of the following four topics community hospital statistics; employment, hours, and earnings in the private health sector; prices; and national economic indicators. These statistics are valuable in their own right for understanding the relationship between the health care sector and the overall economy. In addition, they provide indicators of the direction and magnitude of health care costs prior to the availability of more ...

  17. Care in Feminist Economics

    OpenAIRE

    Hara, Nobuko; 原, 伸子

    2006-01-01

    This article reviews the literature in the field of care in terms of theconcept and methodology. This is an area that has been under theorisedin mainstream economics, but that has received considerable attentionover the last few decades by feminist economics. The provisioning ofcaring service is a social as well as an economic issue and it is increasinglydifficult even for conventional economics to consider caringactivities. The integration of caring situation into economic thinkingposes the ...

  18. Health Care International

    OpenAIRE

    2006-01-01

    This is an interactive quiz for the team representing the Health Care International (HCI) in an educational game to clarify its role and relationship with other provincial reconstruction teams (PRTs), non-governmental organizations (NGOs), and international organizations (IOs) involved in the broad area of humanitarian assistance, relief operations, development and reconstruction in Afghanistan. The educational game involves the following organizations: Health Care International (HCI), Afghan...

  19. Caring finance practices

    OpenAIRE

    Staveren, Irene

    2013-01-01

    textabstractThe 2008 financial crisis has demonstrated the failure of both utilitarian and deontological ethics in finance. Alternatives do not need to be created from nothing, because the crisis itself has stimulated the emergence of ethically sound finance practices from within the sector. This article presents two cases of such alternatives, which can be understood as caring finance. Caring finance is built around more personal relationships, responsibility, and risk reduction. The example...

  20. Spirometry in primary care

    OpenAIRE

    Allan L Coates; Brian L Graham; McFadden, Robin G; Colm McParland; Dilshad Moosa; Steeve Provencher; Jeremy Road

    2013-01-01

    Canadian Thoracic Society (CTS) clinical guidelines for asthma and chronic obstructive pulmonary disease (COPD) specify that spirometry should be used to diagnose these diseases. Given the burden of asthma and COPD, most people with these diseases will be diagnosed in the primary care setting. The present CTS position statement was developed to provide guidance on key factors affecting the quality of spirometry testing in the primary care setting. The present statement may also be used to inf...

  1. Nursing care community health

    Directory of Open Access Journals (Sweden)

    Diana Acosta-Salazar

    2016-07-01

    Full Text Available Process Nursing Care (PAE is a systematic tool that facilitates the scientificity of care in community practice nurse, the application of scientific method in community practice, allows nursing to provide care in logical, systematic and comprehensive reassessing interventions to achieve the proposed results. It began with the valuation of Marjory Gordon Functional Patterns and then at the stage of diagnosis and planning North American Nursing Diagnosis Association (NANDA, Nursing Interventions Classification (NIC and Nursing Outcomes Classification (NOC is interrelate. It is a descriptive and prospective study. Diagnosis was made by applying the instruments measuring scale of the socio-demographic characteristics, symptom questionnaire for early detection of mental disorders in the community and appreciation for functional patterns. The PAE includes more frequent diagnoses, criteria outcomes, indicators, interventions and activities to manage community issues. alteration was evidenced in patterns: Adaptation and Stress Tolerance, Self-perception-Self-concept-, Role-Relationships, sleep and rest and Perception and Health Management. A standardized NANDA-NIC-NOC can provide inter care holistic care from the perspective of community mental health with a degree of scientific nature that frames the professional work projecting the individual, family and community care.

  2. Wound care in horses.

    Science.gov (United States)

    Caston, Stephanie S

    2012-04-01

    Care of equine wounds in the field can be a challenging endeavor. Many times, wound care is complicated by chronicity or by prior inappropriate care in addition to the great degree of tissue trauma that occurred when the horse was wounded. Recognizing involvement of synovial structures, loss of skin, and damage to bone are critical in the initial examination of wounds and will guide future care. Education of clients is also important in that preparing them for possible outcomes during healing may help improve compliance and proper treatment of wound. Owners and trainers often perform much of the daily care and monitoring of equine wounds and thus can greatly assist or impede the progress. Bandaging is important to management of equine wounds-especially on the limbs-and is sometimes overlooked because of its labor-intensive nature and the desire for a spray, ointment, or salve that will heal the wound. The practitioner that improves and utilizes his or her understanding of the wound-healing process in concert with his or her knowledge of local anatomy will be the one who is best equipped to care for wounds in ambulatory practice.

  3. A Vocational Calling: Exploring a Caring Technology in Elderly Care

    Science.gov (United States)

    Fejes, Andreas; Nicoll, Katherine

    2010-01-01

    In this article we explore the relationship of care of a group of health care workers in elderly care, through their descriptions of themselves and their work. We have an interest in how relationships of care may be explored and characterised in and across disparate vocational settings. This is a critical response to policy discourses of…

  4. Primary care nurses: effects on secondary care referrals for diabetes?

    NARCIS (Netherlands)

    Dijk, C.E. van; Verheij, R.A.; Hansen, J.; Velden, L. van der; Nijpels, G.; Groenewegen, P.P.; Bakker, D.H. de

    2010-01-01

    BACKGROUND: Primary care nurses play an important role in diabetes care, and were introduced in GP-practice partly to shift care from hospital to primary care. The aim of this study was to assess whether the referral rate for hospital treatment for diabetes type II (T2DM) patients has changed with t

  5. Developing Integrated Care: Towards a development model for integrated care

    OpenAIRE

    Minkman, Mirella M.N

    2012-01-01

    textabstractThe thesis adresses the phenomenon of integrated care. The implementation of integrated care for patients with a stroke or dementia is studied. Because a generic quality management model for integrated care is lacking, the study works towards building a development model for integrated care. Based on a systematic approach in which a literature study, a delphi study, a concept mapping study and questionnaire research are combined, a development model for integrated care is created....

  6. Perspectives on Self-Care

    Science.gov (United States)

    Williams, Isha D.; Richardson, Tenille A.; Moore, Darren D.; Gambrel, Laura Eubanks; Keeling, Margaret L.

    2010-01-01

    Self-care for clinicians is much needed. To discover ways to implement self-care into our lives, we (four therapists) tried different self-care methods over a span of one to two weeks. After using practices that explored self-care through mindfulness meditation, autohypnosis, music, and spirituality, we wrote about the outcome of these experiences…

  7. Smart Living in Dementia Care

    NARCIS (Netherlands)

    Nijhof, N.; Hoof, van J; Blom, M.M.; Gemert-Pijnen, van J.E.W.C.; Hoof, van Joost; Demiris, George; Wouters, Eveline J.M.

    2015-01-01

    In order to provide adequate care and housing to the growing number of people with dementia, new technologies are necessary to provide good care and reduce the costs for these care services. Numerous technologies are available, which decrease the need for care and increase the self-reliance of clien

  8. Maryland Day Care Voucher System.

    Science.gov (United States)

    Hildebrand, Joan M.

    This manual was written to assist States and other governmental units wishing to replicate the Maryland Day Care Voucher Program, a system of providing child care subsidies to eligible families. Chapter I provides brief histories of day care in Maryland and that State's grant to demonstrate the viability of a day care voucher system. Chapter II…

  9. Society of Critical Care Medicine

    Science.gov (United States)

    ... Care App Social Media Critical Care Statistics eCommunity Media Relations SmartBrief SCCM App Education Center Annual Congress Program ... Care App Social Media Critical Care Statistics eCommunity Media Relations SmartBrief SCCM App Education Center Annual Congress Program ...

  10. Health care technology assessment

    Science.gov (United States)

    Goodman, Clifford

    1994-12-01

    The role of technology in the cost of health care is a primary issue in current debates concerning national health care reform. The broad scope of studies for understanding technological impacts is known as technology assessment. Technology policy makers can improve their decision making by becoming more aware, and taking greater advantage, of key trends in health care technology assessment (HCTA). HCTA is the systematic evaluation of the properties, impacts, and other attributes of health care technologies, including: technical performance; clinical safety and efficacy/effectiveness; cost-effectiveness and other economic attributes; appropriate circumstances/indications for use; and social, legal, ethical, and political impacts. The main purpose of HCTA is to inform technology-related policy making in health care. Among the important trends in HCTA are: (1) proliferation of HCTA groups in the public and private sectors; (2) higher standards for scientific evidence concerning technologies; (3) methodological development in cost analyses, health-related quality of life measurement, and consolidation of available scientific evidence (e.g., meta-analysis); (4) emphasis on improved data on how well technologies work in routine practice and for traditionally under-represented patient groups; (5) development of priority-setting methods; (6) greater reliance on medical informatics to support and disseminate HCTA findings.

  11. Multidisciplinary care in haemoglobinopathies

    Directory of Open Access Journals (Sweden)

    Adriana Ceci

    2014-12-01

    Full Text Available While most complications are related to haemoglobinopathies and their treatment, it is also possible to observe substantial differences in comorbidities’ onset and seriousness which depend also to the different HPs genotypes. These differences should be carefully considered when health authorities set up and manage adequate care systems and treatments plans. We describe services organisation in Italy including the availability of multispecialty care and tools, in the HPs units participating to the HTA-THAL Multiregional Registry, with the aim to derive the impact of the services and multispecialty care availability on the management of the disease and on the patients wellbeing. The high dispersion and heterogeneity of services demonstrated, exposes the Italian system to a high risk of: a inappropriate use of economical and medical resources, b limited access to multidisciplinary care of some patients with apparent inequality among different centres, and c low patients satisfaction with the services provided. The identification of a ‘standard for HPs services’ is necessary not only at national but also at interventional level in order to implement collaborative research and the identification and networking of reference’ centres worldwide. Following the big efforts provided in the last years here there is a new challenging mission for the TIF.

  12. Palliative care and spirituality

    Directory of Open Access Journals (Sweden)

    Narayanasamy Aru

    2007-01-01

    Full Text Available Critical junctures in patients′ lives such as chronic illnesses and advanced diseases may leave the persons in a state of imbalance or disharmony of body, mind and spirit. With regard to spirituality and healing, there is a consensus in literature about the influence of spirituality on recovery and the ability to cope with and adjust to the varying and demanding states of health and illness. Empirical evidence suggests that spiritual support may act as an adjunct to the palliative care of those facing advanced diseases and end of life. In this article, the author draws from his empirical work on spirituality and culture to develop a discourse on palliative care and spirituality in both secular and non-secular settings. In doing so, this paper offers some understanding into the concept of spirituality, spiritual needs and spiritual care interventions in palliative care in terms of empirical evidence. Responding to spiritual needs could be challenging, but at the same time it could be rewarding to both healthcare practitioner (HCP and patient in that they may experience spiritual growth and development. Patients may derive great health benefits with improvements in their quality of life, resolutions and meaning and purpose in life. It is hoped that the strategies for spiritual support outlined in this paper serve as practical guidelines to HCPs for development of palliative care in South Asia.

  13. Bioethics and caring.

    Science.gov (United States)

    van Hooft, S

    1996-04-01

    The author agrees with the critiques of moral theory offered by such writers as Bernard Williams and Alasdair MacIntyre, and uses ideas from Heidegger and Levinas to argue that caring is an ontological structure of human existence which takes two forms: caring about on self (which he calls our "self-project") and caring-about-others. This dual form of caring is expressed on four Aristotelian levels of human living which the author describes and illustrates with reference to the phenomenon of pain. It is concluded from this analysis that traditional notions of morality as imposing obligations should give way to an understanding of ethics as the social forms given to our caring for ourselves and for others. A number of implications for ethical theory are sketched out with the conclusion that virtue theory should be preferred and that the model could be worked out more fully to show that virtue theory can be internalist, particularist, pluralist, personalist and objectivist. PMID:8731533

  14. Managed care under siege.

    Science.gov (United States)

    Epstein, R A

    1999-10-01

    Managed Care Organizations (MCOs) are frequently criticized for their marketing mistakes. Often that criticism is leveled against an implicit benchmark of an ideal competitive market or an ideal system of government provision. But any accurate assessment in the choice of health care organizations always requires a comparative measure of error rates. These are high in the provision of health care, given the inherent uncertainties in both the cost and effectiveness of treatment. But the continuous and rapid evolution of private health care mechanisms is, in the absence of regulation, more likely to secure access and contain costs than any system of government regulation. State regulation is subject to the risk of capture and to the sluggish and acquisitive behavior of state run monopolies. The proposed fixes for the MCOs (rights to specialists, access to physicians outside the network, guaranteed emergency room access) are likely, when imposed from without, to cost more than they are worth. The long-term risk is that markets will fail under regulation, paving the way for greater losses from massive government control of the health care delivery system.

  15. Mercury and health care

    Directory of Open Access Journals (Sweden)

    Rustagi Neeti

    2010-01-01

    Full Text Available Mercury is toxic heavy metal. It has many characteristic features. Health care organizations have used mercury in many forms since time immemorial. The main uses of mercury are in dental amalgam, sphygmomanometers, and thermometers. The mercury once released into the environment can remain for a longer period. Both acute and chronic poisoning can be caused by it. Half of the mercury found in the atmosphere is human generated and health care contributes the substantial part to it. The world has awakened to the harmful effects of mercury. The World Health Organization and United Nations Environmental Programme (UNEP have issued guidelines for the countries′ health care sector to become mercury free. UNEP has formed mercury partnerships between governments and other stakeholders as one approach to reducing risks to human health and the environment from the release of mercury and its compounds to the environment. Many hospitals are mercury free now.

  16. Mercury and health care

    Science.gov (United States)

    Rustagi, Neeti; Singh, Ritesh

    2010-01-01

    Mercury is toxic heavy metal. It has many characteristic features. Health care organizations have used mercury in many forms since time immemorial. The main uses of mercury are in dental amalgam, sphygmomanometers, and thermometers. The mercury once released into the environment can remain for a longer period. Both acute and chronic poisoning can be caused by it. Half of the mercury found in the atmosphere is human generated and health care contributes the substantial part to it. The world has awakened to the harmful effects of mercury. The World Health Organization and United Nations Environmental Programme (UNEP) have issued guidelines for the countries’ health care sector to become mercury free. UNEP has formed mercury partnerships between governments and other stakeholders as one approach to reducing risks to human health and the environment from the release of mercury and its compounds to the environment. Many hospitals are mercury free now. PMID:21120080

  17. Health care reforms

    Directory of Open Access Journals (Sweden)

    Marušič Dorjan

    2016-09-01

    Full Text Available In large systems, such as health care, reforms are underway constantly. The article presents a definition of health care reform and factors that influence its success. The factors being discussed range from knowledgeable personnel, the role of involvement of international experts and all stakeholders in the country, the importance of electoral mandate and governmental support, leadership and clear and transparent communication. The goals set need to be clear, and it is helpful to have good data and analytical support in the process. Despite all debates and experiences, it is impossible to clearly define the best approach to tackle health care reform due to a different configuration of governance structure, political will and state of the economy in a country.

  18. [Quality of health care].

    Science.gov (United States)

    Medina, J L; De Melo, P C

    2000-01-01

    Quality assurance is a relatively recent concern but already plays a major role in health care management and provision. Quality involves the definition of a comprehensive programme tailored by realistic and effective objectives and norms that include the structured review of procedures (namely clinical audits) and the use of up-to-date protocols. The involvement and motivation of health professionals, together with an adequate internal and external communication strategy, play a key role in the planning and application of these programmes. The use of programmed assessment, based on a solid knowledge of current practice, should have practical implications, optimising procedures in order to improve the quality of care. This commitment towards quality in health care should go far beyond governmental policy and should have clear support from health professionals. PMID:11234496

  19. Rabbit care and husbandry.

    Science.gov (United States)

    Bradley, Teresa

    2004-05-01

    This article provides information for the veterinary staff to be better prepared to care for the special needs of rabbit patients as they are presented in increased frequency for veterinary care. Housing, nutrition,restraint, and recognizing illness are covered in detail. Descriptions of techniques for blood collection, oral medication administration, and injection sites are included. Preventive care recommendations for examinations from first visit to geriatric visits are outlined as well as indications for spaying and neutering. Also provided are lists that will aid the veterinary staff in providing instructions when the appointment is made, recommendations for boarding, surgical, and anesthetic considerations and clinical signs that are associated with pain in rabbits. PMID:15145392

  20. Critical care in India.

    Science.gov (United States)

    Udwadia, F E; Guntupalli, K K; Vidyasagar, D

    1997-04-01

    India is a vast democracy of nearly one billion people. Before the British rule ended in 1947, the life span of an Indian was a mere 21 years. Within a short span of 50 years, it increased to an impressive 63 years, largely due to public health measures initiated by the government. This created a pool of more than 300 million middle class Indians who could afford the benefits of modern and specialized care when needed. Critical care medicine, as practiced in the West, is still confined to large Metropolitan areas. A large pool of expatriate Indian physicians from all over the world are helping bridge the resource gap between the West and India by transfer of technology and providing appropriate training to physicians and paramedical personnel. This article describes the history and current status of development of critical care medicine in India. PMID:9107510

  1. The Mediatization of Care

    DEFF Research Database (Denmark)

    Dindler, Camilla; Ahlmark, Nanna

    This paper will explore the implications for peer-to-peer health interventions of two developments in modern Western societies; the increasing status of the media as a site for gaining governmental legitimacy (Schillemanns, 2012) and a neoliberal “logic of choice” in health care, focusing...... on citizens’ individual risk and responsibilities in pursuing “factual” health (Mol, 2008). The practice of peer-to-peer health intervention may, as opposed to the logic of choice, be guided by a “logic of care” (Mol, 2008) , defined as a professional way of doing that attunes into the everyday life...... in health care defined partly by a democratization of health expertise and the abovementioned logic of care, when – at the same time - there is an experienced need of gaining public legitimacy and status via linking to the agendas of the media and broader culture that promote an individualized, risk aware...

  2. Mercury and health care.

    Science.gov (United States)

    Rustagi, Neeti; Singh, Ritesh

    2010-08-01

    Mercury is toxic heavy metal. It has many characteristic features. Health care organizations have used mercury in many forms since time immemorial. The main uses of mercury are in dental amalgam, sphygmomanometers, and thermometers. The mercury once released into the environment can remain for a longer period. Both acute and chronic poisoning can be caused by it. Half of the mercury found in the atmosphere is human generated and health care contributes the substantial part to it. The world has awakened to the harmful effects of mercury. The World Health Organization and United Nations Environmental Programme (UNEP) have issued guidelines for the countries' health care sector to become mercury free. UNEP has formed mercury partnerships between governments and other stakeholders as one approach to reducing risks to human health and the environment from the release of mercury and its compounds to the environment. Many hospitals are mercury free now.

  3. Maritime in transit care.

    Science.gov (United States)

    Bott, G; Barnard, J; Prior, K

    2015-01-01

    Operation GRITROCK saw the first operational deployment of the Maritime In Transit Care team from the Role 2 (Enhanced) (R2(E)) Medical Treatment Facility, which is able to provide Damage Control Surgery and the limited holding of patients, situated on board RFA ARGUS. Whilst the Medical Emergency Response Team demonstrated the capability of advanced military Pre-Hospital Emergency Care (PHEC) on Op HERRICK, the need to provide a similar high level of care on contingency operations was recognised. Op GRITROCK allowed for the continued exploration of a maritime capability from an established R2(E) platform whilst providing medical evacuation capability for a significant population at risk distributed over a large Joint Operation Area. Although the patient load during the operation was low, key lessons were learnt and opportunities identified to further develop the newly recognised sub-speciality of PHEC, both medically and logistically, and these will be discussed in this article. PMID:26867404

  4. Health care need

    DEFF Research Database (Denmark)

    Hasman, Andreas; Hope, Tony; Østerdal, Lars Peter

    2006-01-01

    The argument that scarce health care resources should be distributed so that patients in 'need' are given priority for treatment is rarely contested. In this paper, we argue that if need is to play a significant role in distributive decisions it is crucial that what is meant by need can be precis......The argument that scarce health care resources should be distributed so that patients in 'need' are given priority for treatment is rarely contested. In this paper, we argue that if need is to play a significant role in distributive decisions it is crucial that what is meant by need can...... be precisely articulated. Following a discussion of the general features of health care need, we propose three principal interpretations of need, each of which focuses on separate intuitions. Although this account may not be a completely exhaustive reflection of what people mean when they refer to need...

  5. Neurocritical care update.

    Science.gov (United States)

    Kuroda, Yasuhiro

    2016-01-01

    This update comprises six important topics under neurocritical care that require reevaluation. For post-cardiac arrest brain injury, the evaluation of the injury and its corresponding therapy, including temperature modulation, is required. Analgosedation for target temperature management is an essential strategy to prevent shivering and minimizes endogenous stress induced by catecholamine surges. For severe traumatic brain injury, the diverse effects of therapeutic hypothermia depend on the complicated pathophysiology of the condition. Continuous electroencephalogram monitoring is an essential tool for detecting nonconvulsive status epilepticus in the intensive care unit (ICU). Neurocritical care, including advanced hemodynamic monitoring, is a fundamental approach for delayed cerebral ischemia following subarachnoid hemorrhage. We must be mindful of the high percentage of ICU patients who may develop sepsis-associated brain dysfunction. PMID:27239312

  6. Integrated care requires integrated supervision

    OpenAIRE

    Ketelaars, Corry

    2011-01-01

    Introduction: Given recent developments in integrated care, it is becoming increasingly important for the Dutch Health Care Inspectorate to direct its supervision in a way that may help speed up the implementation of integrated care.Description of care practice: Since the implementation of integrated care for chronic patients is facing obstacles, alternative methods are required to ensure that the implementation process does not run into any delays. By applying a risk-based approach to integr...

  7. What Is Primary Care Informatics?

    OpenAIRE

    de Lusignan, Simon

    2003-01-01

    Primary care informatics is an emerging academic discipline that remains undefined. The unique nature of primary care necessitates the development of its own informatics discipline. A definition of primary care informatics is proposed, which encompasses the distinctive nature of primary care. The core concepts and theory that should underpin it are described. Primary care informatics is defined as a science and as a subset of health informatics. The proposed definition is intended to focus th...

  8. Pediatric palliative care

    Directory of Open Access Journals (Sweden)

    Trapanotto Manuela

    2008-12-01

    Full Text Available Abstract The WHO defines pediatric palliative care as the active total care of the child's body, mind and spirit, which also involves giving support to the family. Its purpose is to improve the quality of life of young patients and their families, and in the vast majority of cases the home is the best place to provide such care, but for cultural, affective, educational and organizational reasons, pediatric patients rarely benefit from such an approach. In daily practice, it is clear that pediatric patients experience all the clinical, psychological, ethical and spiritual problems that severe, irreversible disease and death entail. The international literature indicates a prevalence of incurable disease annually affecting 10/10,000 young people from 0 to 19 years old, with an annual mortality rate of 1/10,000 young people from birth to 17 years old. The needs of this category of patients, recorded in investigations conducted in various parts of the world, reveal much the same picture despite geographical, cultural, organizational and social differences, particularly as concerns their wish to be treated at home and the demand for better communications between the professionals involved in their care and a greater availability of support services. Different patient care models have been tested in Italy and abroad, two of institutional type (with children staying in hospitals for treating acute disease or in pediatric hospices and two based at home (the so-called home-based hospitalization and integrated home-based care programs. Professional expertise, training, research and organization provide the essential foundations for coping with a situation that is all too often underestimated and neglected.

  9. Concept caring in nursing

    Directory of Open Access Journals (Sweden)

    Lenka Drahošová

    2016-05-01

    Full Text Available Aim: The aim of this literature review was to search for qualitative studies focusing on the concept of caring in nursing, to analyse them and to synthesize knowledge that concerns the definition of the concept of caring in nursing from the point of view of nurses and patients. Design: Review. Methods: Qualitative studies were searched for systematically in the electronic databases Academic Search Complete (EBSCO, CINAHL, Medline, Science Direct, and the Wiley Library Online, according to set criteria and defined key words for the period 1970-2015. Seven selected articles were analysed after selection of documents with the aid of a sorting chart. Results: Nurses understand caring in nursing as a relationship with patients which is characterised on the nurses' part by an individual and empathetic approach, attentiveness, experience and sensitivity. Through caring, active communication takes place, providing information which reduces anxiety and leads to the breaking down of barriers. This relationship helps protect patients' autonomy, dignity and comfort. It requires experience on the part of nurses, and it is influenced by the environment. The nurses' personal qualities (what professional knowledge, attitudes and skills they have and their availability, reliability, and emotional and physical support are important to patients. Conclusion: The concept of caring is a content specific interpersonal process which is characterized by the professional knowledge, skills, personal maturity, and interpersonal sensitivity of nurses, which result in the protection, emotional support, and the meeting of bio-psycho-social needs of patients. The results of the overview study could contribute to an explanation and understanding of the nature of caring as a fundamental feature of the discipline of nursing.

  10. School Leadership--Balancing Power with Caring.

    Science.gov (United States)

    Sernak, Kathleen

    This book examines caring from three perspectives. It opens with a discussion of Nel Noddings's caring tenets--caring is collaborative, situational, reciprocal, and committed--that are seen as necessary for an ethic of caring. A critique of an ethic of caring from the viewpoints of caring with leadership, caring as a "female ethic," caring for a…

  11. Psychiatry and primary care.

    Science.gov (United States)

    Goldberg, David

    2003-10-01

    There is now almost universal recognition that primary care is the place where most mentally distressed people first present for help. However, the pace at which the health system has adapted to this reality varies greatly from country to country, depending on the amount of resource devoted to mental illness services, the way in which primary care physicians have organized their practice, and the inertia of the system. Here we present several models from developed and developing countries and address briefly the issue of training of health workers. PMID:16946921

  12. Retaining caregivers, improving care.

    Science.gov (United States)

    Bodwell, Wendy; Dent, Sara; Grant, Tracie; Hammerly, Milt; Mamula, Jeanie

    2006-01-01

    Text Summary In 2004, Centura Health's long-term care centers took part in a pilot project, sponsored by the Centers for Medicare & Medicaid Services, called "Improving Nursing Home Culture through Workforce Retention." A 30-member team comprising Centura leaders and long-term facility staff looked at Centura's eight participating facilities through residents' and employees' eyes. The goal of the team's reflection and subsequent changes was to create a culture in which decisions are focused on resident care and organizational policies are based on respect for employees. At the end of the first year, residents seemed happier and employee satisfaction and involvement increased at all eight Centura facilities. PMID:16519278

  13. Advance Care Planning

    Science.gov (United States)

    The thirteenth module of the EPEC-O (Education in Palliative and End-of-Life Care for Oncology) Self-Study: Cultural Considerations When Caring for African Americans explores the attitudes and practices of African Americans related to completion of advance directives, and recommends effective strategies to improve decision-making in the setting of serious, life-threatening illness, in ways that augment patient autonomy and support patient-centered goal-setting and decision-making among African American patients and their families.

  14. Auditing urinary catheter care.

    Science.gov (United States)

    Dailly, Sue

    Urinary catheters are the main cause of hospital-acquired urinary tract infections among inpatients. Healthcare staff can reduce the risk of patients developing an infection by ensuring they give evidence-based care and by removing the catheter as soon as it is no longer necessary. An audit conducted in a Hampshire hospital demonstrated there was poor documented evidence that best practice was being carried out. Therefore a urinary catheter assessment and monitoring tool was designed to promote best practice and produce clear evidence that care had been provided. PMID:22375340

  15. Pharmacists belong in accountable care organizations and integrated care teams.

    Science.gov (United States)

    Smith, Marie; Bates, David W; Bodenheimer, Thomas S

    2013-11-01

    Effective health care workforce development requires the adoption of team-based care delivery models, in which participating professionals practice at the full extent of their training in pursuit of care quality and cost goals. The proliferation of such new models as medical homes, accountable care organizations, and community-based care teams is creating new opportunities for pharmacists to assume roles and responsibilities commensurate with their capabilities. Some challenges to including pharmacists in team-based care delivery models, including the lack of payment mechanisms that explicitly provide for pharmacist services, have yet to be fully addressed by policy makers and others. Nevertheless, evolving models and strategies reveal a variety of ways to draw on pharmacists' expertise in such critical areas as medication management for high-risk patients. As Affordable Care Act provisions are implemented, health care workforce projections need to consider the growing number of pharmacists expected to play an increasing role in delivering primary care services.

  16. Integrating palliative care into the trajectory of cancer care.

    Science.gov (United States)

    Hui, David; Bruera, Eduardo

    2016-03-01

    Over the past five decades, palliative care has evolved from serving patients at the end of life into a highly specialized discipline focused on delivering supportive care to patients with life-limiting illnesses throughout the disease trajectory. A growing body of evidence is now available to inform the key domains in the practice of palliative care, including symptom management, psychosocial care, communication, decision-making, and end-of-life care. Findings from multiple studies indicate that integrating palliative care early in the disease trajectory can result in improvements in quality of life, symptom control, patient and caregiver satisfaction, illness understanding, quality of end-of-life care, survival, and costs of care. In this narrative Review, we discuss various strategies to integrate oncology and palliative care by optimizing clinical infrastructures, processes, education, and research. The goal of integration is to maximize patient access to palliative care and, ultimately, to improve patient outcomes. We provide a conceptual model for the integration of supportive and/or palliative care with primary and oncological care. We also discuss how health-care systems and institutions need to tailor integration based on their resources, size, and the level of primary palliative care available.

  17. Integrating rheumatology care in the community: can shared care work?

    Directory of Open Access Journals (Sweden)

    Anita YN Lim

    2015-08-01

    Full Text Available Introduction: Singapore's rapidly ageing population and chronic disease burden at public hospital specialist clinics herald a silver tsunami. In Singapore, “right siting” aims to manage stable chronic disease in primary care at a lower cost. To improve the quality of rheumatology care, we created shared care between rheumatologist and family physician to reduce hospital visits. Methods: Clinical practice improvement methodology was used to structure shared care of stable patients between hospital rheumatologists and eleven community family physicians; one ran a hospital clinic. A case manager coordinated the workflow. Results: About 220 patients entered shared care over 29 months. Patients without hospital subsidies (private patients and private family physicians independently predicted successful shared care, defined as one cycle of alternating care. Discussion: Our shared care model incorporated a case manager, systematic workflows, patient selection criteria, willing family physician partners and rheumatologists in the absence of organizational integration. Health care affordability impacts successful shared care. Government subsidy hindered right siting to private primary care. Conclusions: Financing systems in Singapore, at health policy level, must allow transfer of hospital subsidies to primary care, both private and public, to make it more affordable than hospital care. Structural integration will create a seamless continuum between hospital and primary care.

  18. Integrating rheumatology care in the community: can shared care work?

    Directory of Open Access Journals (Sweden)

    Anita YN Lim

    2015-08-01

    Full Text Available Introduction: Singapore's rapidly ageing population and chronic disease burden at public hospital specialist clinics herald a silver tsunami. In Singapore, “right siting” aims to manage stable chronic disease in primary care at a lower cost. To improve the quality of rheumatology care, we created shared care between rheumatologist and family physician to reduce hospital visits.Methods: Clinical practice improvement methodology was used to structure shared care of stable patients between hospital rheumatologists and eleven community family physicians; one ran a hospital clinic. A case manager coordinated the workflow.Results: About 220 patients entered shared care over 29 months. Patients without hospital subsidies (private patients and private family physicians independently predicted successful shared care, defined as one cycle of alternating care.Discussion: Our shared care model incorporated a case manager, systematic workflows, patient selection criteria, willing family physician partners and rheumatologists in the absence of organizational integration. Health care affordability impacts successful shared care. Government subsidy hindered right siting to private primary care.Conclusions: Financing systems in Singapore, at health policy level, must allow transfer of hospital subsidies to primary care, both private and public, to make it more affordable than hospital care. Structural integration will create a seamless continuum between hospital and primary care.

  19. Dare to Care, Care to Perform

    DEFF Research Database (Denmark)

    Giangreco, Antonio; Sebastiano, Antnio; Carugati, Andrea

    2010-01-01

    Over the last couple of decades, the modernization of the health sector has been supported by significant investments in IT. Notwithstanding, the results have been often relatively discouraging when compared to other sectors such as banking and insurance. As a consequence, the IT-driven moderniza...... (patients and users), then it will produce positive results for the organization. In other words, who dares to care, will perform.......Over the last couple of decades, the modernization of the health sector has been supported by significant investments in IT. Notwithstanding, the results have been often relatively discouraging when compared to other sectors such as banking and insurance. As a consequence, the IT......-driven modernization literature on the health sector mostly concentrates on the causes of those failures, neglecting therefore the positive experiences. Following the AoM Health Management Track 2008 call for the need of dissemination of best experiences in the health sector, this paper focuses on the IT...

  20. Why do care workers withdraw from elderly care?

    DEFF Research Database (Denmark)

    Liveng, Anne

    2012-01-01

    relations, independently of whether we are in the role of care providers or care receivers. Through collusion theory, the interpretation accepts both the anxiety which the helpless elderly people arouse in the care workers and their motivation for care work as two sides of a subjectively important theme....... The article illustrates how working consciously with the researcher's subjectivity makes it possible to understand apparently irrational patterns. The insights thus gained may be used to prevent withdrawals in care work as an argument for care workers' need for emotional supervision....

  1. Care platforms: a basic building block for care delivery.

    Science.gov (United States)

    Bohmer, Richard M J; Lawrence, David M

    2008-01-01

    Without significant operational reform within the nation's health care delivery organizations, new financing models, payment systems, or structures are unlikely to realize their promise. Adapting insights from high-performing companies in other high-risk, high-cost, science- and technology-based industries, we propose the "care platform" as an organizing framework for internal operations in diversified provider organizations to increase the quality, reliability, and efficiency of care delivery. A care platform organizes "care production" around similar work, rather than organs or specialties; integrates standard and custom care processes; and surrounds them with specifically configured information and business systems. Such organizational designs imply new roles for physicians. PMID:18780920

  2. Circles of Care

    Science.gov (United States)

    Weissbourd, Richard; Jones, Stephanie M.

    2014-01-01

    James is 14 years old. Tall, handsome, funny, athletic, attuned to others, he is one of the popular, high-status students in his large freshman class. He can also be remarkably caring and attentive with his close friends. But James has a dark side. Sometimes he uses his social skills to manipulate others, and he draws a bright line between those…

  3. Net4Care platform

    DEFF Research Database (Denmark)

    2012-01-01

    , that in turn enables general practitioners and clinical staff to view observations. Use the menus above to explore the site's information resources. To get started, follow the short Hello, World! tutorial. The Net4Care project is funded by The Central Denmark Region and EU via Caretech Innovation....

  4. Spectator Medical Care.

    Science.gov (United States)

    Carlson, L

    1992-01-01

    Recent world events-including the fear of terrorism during last year's Super Bowl-illustrate how vulnerable spectators can be to medical emergencies during sporting events. A physician who studies and coordinates crowd care for events ranging from the Super Bowl to local fairs gives tips on planning and executing a spectator medical plan.

  5. Diabetic Wound Care

    Science.gov (United States)

    ... RSS Home » Learn About Feet » Foot Health Information Diabetic Wound Care What is a Diabetic Foot Ulcer? A diabetic foot ulcer is an open sore or wound ... key factors in the appropriate treatment of a diabetic foot ulcer: Prevention of infection Taking the pressure ...

  6. Wound care centers

    Science.gov (United States)

    ... different types of dressings, including: Gels Foams Gauze Films Your provider may use one or multiple types ... Care (AAWC). 2010. http://aawconline.org/wp-content/uploads/2011/08/AAWCPressureUlcerGuidelineofGuidelinesAug11.pdf. Accessed June 11, 2014. ...

  7. Prehospital care in Indonesia

    OpenAIRE

    Pitt, E.; Pusponegoro, A

    2005-01-01

    Current system: Hospitals of varying standards are widespread but have no system of emergency ambulance or patient retrieval. Indonesia's only public emergency ambulance service, 118, is based in five of the biggest cities and is leading the way in paramedic training and prehospital care.

  8. Improving palliative care.

    LENUS (Irish Health Repository)

    Moran, Sue

    2009-05-01

    Any service improvement project requires planning, action and evaluation. Using a recognised quality improvement framework can offer a structured approach to implementing and assessing changes to patient care. This article describes how use of the Deming Cycle has helped to identify nurses\\' learning needs.

  9. History of Chiropractic Care

    Science.gov (United States)

    ... ACA News Digital Edition Archives: ACA News Articles Advertising Opportunities News Newsroom News Releases Letters to the Editor Facts About Chiropractic Chiropractic in the Media ACA Radio Chiropractic Cares Social Media Facebook Twitter YouTube Instagram LinkedIn Advocacy Regulatory Policy Issue ...

  10. Funding Rural Health Care.

    Science.gov (United States)

    Moore, Kim

    This paper provides first-time grant writers with suggestions on how to approach a private funding source. While intended for rural health care advocates, the remarks are equally applicable for educators and others. The rural crisis has produced many heart-rending stories about medically indigent people, but there is a lack of reliable statistics…

  11. Care Ethics in Education.

    Science.gov (United States)

    Shelby, Candice L.

    2003-01-01

    Difficulties with current models of ethics education (correct reasoning, virtue theory, directive moral education) include emphasis on reward/punishment and a presumptive bias toward abstract reasoning. Teaching a care-based ethics would promote a fuller notion of mature moral agents and broaden the school climate beyond compliance. (Contains 19…

  12. Caring for Latino patients.

    Science.gov (United States)

    Juckett, Gregory

    2013-01-01

    Latinos comprise nearly 16 percent of the U.S. population, and this proportion is anticipated to increase to 30 percent by 2050. Latinos are a diverse ethnic group that includes many different cultures, races, and nationalities. Barriers to care have resulted in striking disparities in quality of health care for these patients. These barriers include language, lack of insurance, different cultural beliefs, and in some cases, illegal immigration status, mistrust, and illiteracy. The National Standards for Culturally and Linguistically Appropriate Services address these concerns with recommendations for culturally competent care, language services, and organizational support. Latinos have disproportionately higher rates of obesity and diabetes mellitus. Other health problems include stress, neurocysticercosis, and tuberculosis. It is important to explore the use of alternative therapies and belief in traditional folk illnesses, recognizing that health beliefs are dependent on education, socioeconomic status, and degree of acculturation. Many-but not all-folk and herbal treatments can be safely accommodated with conventional therapy. Physicians must be sensitive to Latino cultural values of simpatia (kindness), personalismo (relationship), respeto (respect), and modestia (modesty). The LEARN technique can facilitate cross-cultural interviews. Some cultural barriers may be overcome by using the "teach back" technique to ensure that directions are correctly understood and by creating a welcoming health care environment for Latino patients. PMID:23317025

  13. Moral Education and Caring

    Science.gov (United States)

    Noddings, Nel

    2010-01-01

    Michael Slote's very interesting work on moral sentimentalism and moral education raises some important questions on the meaning of empathy, the limitations of "inductions", and the development of moral education from the perspective of care ethics. These questions are addressed in this commentary. (Contains 5 notes.)

  14. [Islam and caring].

    Science.gov (United States)

    Nadir, Sihem

    2015-10-01

    There are more and more followers of the Muslim religion in France. All caregivers need to understand the fundamental principles that their Muslim patients hold sacred in the area of health and care. For Muslims, it is of utmost importance to observe the fundamentals of Islam and the values of brotherhood, tolerance, fairness and truth are essential.

  15. Cancer Care and Control

    OpenAIRE

    Schneidman, Miriam; Jeffers, Joanne; Duncan, Kalina

    2015-01-01

    Worldwide, deaths from cancer exceed those caused by human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS), tuberculosis, and malaria combined. Seventy percent of deaths due to cancer occur in low-and middle-income countries, which are often poorly prepared to deal with the growing burden of chronic disease. Over a period of 18 months, the cancer care and control...

  16. Child Care Aware

    Science.gov (United States)

    ... a stream of our activity across multiple social networks by visiting the Child Care Aware® of America Social Dashboard. Visit Our Social Dashboard Follow and Engage Copyright 2015 CCAoA. All Rights Reserved. Careers Privacy Policy Site Terms Newsroom Contact Us Pin It on ...

  17. [Palliative care in neurology].

    Science.gov (United States)

    Provinciali, Leandro; Tarquini, Daniela; De Falco, Fabrizio A; Carlini, Giulia; Zappia, Mario; Toni, Danilo

    2015-07-01

    Palliative care in neurology is characterized by the need of taking into account some distinguishing features which supplement and often differ from the general palliative approach to cancer or to severe organ failures. Such position is emphasized by a new concept of palliative assistance which is not limited to the "end of life" stage, as it was the traditional one, but is applied along the entire course of progressive, life-limiting, and disabling conditions. There are various reasons accounting for a differentiation of palliative care in neurology and for the development of specific expertise; the long duration of the advanced stages of many neurological diseases and the distinguishing features of some clinical problems (cognitive disorders, psychic disorders, etc.), in addition to the deterioration of some general aspects (nutrition, etc.), make the general criteria adopted for cancer, severe respiratory, hepatic or renal failures and heart failure inadequate. The neurological diseases which could benefit from the development of a specific palliative approach are dementia, cerebrovascular diseases, movement disorders, neuromuscular diseases, severe traumatic brain injury, brain cancers and multiple sclerosis, as well as less frequent conditions. The growing literature on palliative care in neurology provides evidence of the neurological community's increasing interest in taking care of the advanced and terminal stages of nervous system diseases, thus encouraging research, training and updating in such direction. This document aims to underline the specific neurological requirements concerning the palliative assistance. PMID:26228722

  18. Health Care Indicators

    OpenAIRE

    Donham, Carolyn S.; Maple, Brenda T.; Lemieux, Jeffrey A.

    1990-01-01

    Contained in this regular feature of the journal is a section on each of the following five topics: community hospital statistics; employment, hours, and earnings in the private health sector; health care prices; hospital skill mix changes: 1980s; and national economic indicators.

  19. Information in Health Care.

    Science.gov (United States)

    Mayeda, Tadashi A.

    The report stresses the fact that while there is unity in the continuum of medicine, information in health care is markedly different from information in medical education and research. This difference is described as an anomaly in that it appears to deviate in excess of normal variation from needs common to research and education. In substance,…

  20. BNFL and environmental care

    International Nuclear Information System (INIS)

    British Nuclear Fuel plc (BNFL) acknowledge a duty of care for the environment and aims to reduce the effects of its activities on the environment to as low as reasonably practicable. Its environmental policy statement is presented and its approach, investment policies and activities to implement this policy are outlined. The activities include energy efficiency, recycling, surveillance and research, conservation and open information. (UK)

  1. Shared Care in Diabetes?

    DEFF Research Database (Denmark)

    Bødker, Keld

    2006-01-01

    The Danish National Board of Health has recently released a report that is intended to mark the start of a new project to establish it support for shared care in diabetes. In this paper I raise a number of concerns where lack of attention towards participation from prospective users constitute...... potential, yet very real, risks for the system not to meet its intended goals....

  2. Orphan Care in Russia

    Directory of Open Access Journals (Sweden)

    Schmidt, Victoria

    2009-07-01

    Full Text Available Current public opinion about the residential care system in contemporary Russia is extremely negative. A majority of Russians, both citizens and professionals, consider that family placement is the best arrangement for orphaned children. The year 2007 was announced as the Year of the Child in Russia. The majority of officials interpreted it as the year of de-institutionalization of the residential care system for children in Russia. De-institutionalization is mostly identified as reform focused on family placement instead of placement in institutions. Vladimir Fridlyanov, the executive director of the Ministry of Science and Education, announced in May, 2007 that the government is going to transfer 120,000 children from institutions into families every year from 2007 until 2010 and reduce the number of residential care institutions by one-third (Nesterova 2007. But the likelihood of family placement is small, with the exception of the adoption of infants without serious pathologies, and the attempts of precipitant de-institutionalization (when children’s homes are closed and children are distributed among families have failed (children were returned into children homes. According to the opinion of the Ministry, the key obstacle to effective de-institutionalization is the lack of professionals in adoption and foster care (Vazhdaeva 2006.

  3. FROM CASH TO CARING

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Shanghai is reinventing itselfas it prepares for the SpecialOlympics in October Known as China’s city of money, Shanghai is soonto find newfameas the country’s capital of caring. With its high-rise skyline, the modern center of business, a meeting place

  4. Children and chiropractic care

    DEFF Research Database (Denmark)

    Hartvigsen, Jan; Hestbaek, Lise

    2009-01-01

    care profession has convincingly assumed the responsibility of spinal and musculoskeletal health for children. Considering the magnitude of the challenges ahead for both researchers and clinicians, this may be a good opportunity for doctors of chiropractic to take responsibility and engage...

  5. Primary care guidelines

    DEFF Research Database (Denmark)

    Ijäs, Jarja; Alanen, Seija; Kaila, Minna;

    2009-01-01

    OBJECTIVE: To describe the adoption of the national Hypertension Guideline in primary care and to evaluate the consistency of the views of the health centre senior executives on the guideline's impact on clinical practices in the treatment of hypertension in their health centres. DESIGN: A cross...

  6. Accountability in Health Care

    DEFF Research Database (Denmark)

    Vrangbæk, Karsten; Byrkjeflot, Haldor

    2016-01-01

    adjustment of such frameworks. In this article we present a framework for analyzing accountability within health care. The paper makes use of the concept of "accountability regime" to signify the combination of different accountability forms, directions and functions at any given point in time. We show...

  7. Shared Oral Care

    DEFF Research Database (Denmark)

    Hede, Børge; Elmelund Poulsen,, Johan; Christophersen, Rasmus;

    2014-01-01

    Shared Oral Care - Forebyggelse af orale sygdomme på plejecentre Introduktion og formål: Mangelfuld mundhygiejne hos plejekrævende ældre er et alment og veldokumenteret sundhedsproblem, der kan føre til massiv udvikling af tandsygdomme, og som yderligere kan være medvirkende årsag til alvorlige...

  8. Welfare and self care

    DEFF Research Database (Denmark)

    Gulløv, Eva

    2011-01-01

    to take care of people’s basic needs but also to enable them to fare well in accordance with the dominant norms of society. This is particularly evident in the case of children. Children are objects of intense normative attention and are invested in as no other social group in order to ensure...

  9. Integrating palliative care with usual care of diabetic foot wounds.

    Science.gov (United States)

    Dunning, Trisha

    2016-01-01

    Palliative care is a philosophy and a system for deciding care and can be used alone or integrated with usual chronic disease care. Palliative care encompasses end-of-life care. Palliative care aims to enhance quality of life, optimize function and manage symptoms including early in the course of chronic diseases. The purposes of this article are to outline palliative care and discuss how it can be integrated with usual care of diabetic foot wounds. Many people with diabetes who have foot wounds also have other comorbidities and diabetes complications such as cardiovascular and renal disease and depression, which affect medicine and other treatment choices, functional status, surgical risk and quality of life. Two broad of diabetic foot disease exist: those likely to heal but who could still benefit from integrated palliative care such as managing pain and those where healing is unlikely where palliation can be the primary focus. People with diabetes can die suddenly, although the life course is usually long with periods of stable and unstable disease. Many health professionals are reluctant to discuss palliative care or suggest people to document their end-of-life care preferences. If such preferences are not documented, the person might not achieve their desired death or place of death and health professionals and families can be confronted with difficult decisions. Palliative care can be integrated with usual foot care and is associated with improved function, better quality of life and greater patient and family satisfaction.

  10. [Managed care. Its impact on health care in the USA, especially on anesthesia and intensive care].

    Science.gov (United States)

    Bauer, M; Bach, A

    1998-06-01

    Managed care, i.e., the integration of health insurance and delivery of care under the direction of one organization, is gaining importance in the USA health market. The initial effects consisted of a decrease in insurance premiums, a very attractive feature for employers. Managed care promises to contain expenditures for health care. Given the shrinking public resources in Germany, managed care seems attractive for the German health system, too. In this review the development of managed care, the principal elements, forms of organisation and practical tools are outlined. The regulation of the delivery of care by means of controlling and financial incentives threatens the autonomy of physicians: the physician must act as a "double agent", caring for the interest for the individual patient and being restricted by the contract with the managed care organisation. Cost containment by managed care was achieved by reducing the fees for physicians and hospitals (and partly by restricting care for patients). Only a fraction of this cost reduction was handed over to the enrollee or employer, and most of the money was returned with profit to the shareholders of the managed care organisations. The preeminent role of primary care physicians as gatekeepers of the health network led to a reduced demand for specialist services in general and for university hospitals and anesthesiologists in particular. The paradigm of managed care, i.e., to guide the patient and the care giver through the health care system in order to achieve cost-effective and high quality care, seems very attractive. The stress on cost minimization by any means in the daily practice of managed care makes it doubtful if managed care should be an option for the German health system, in particular because there are a number of restrictions on it in German law. PMID:9676303

  11. Outbreaks in Health Care Settings.

    Science.gov (United States)

    Sood, Geeta; Perl, Trish M

    2016-09-01

    Outbreaks and pseudo-outbreaks in health care settings can be complex and should be evaluated systematically using epidemiologic tools. Laboratory testing is an important part of an outbreak evaluation. Health care personnel, equipment, supplies, water, ventilation systems, and the hospital environment have been associated with health care outbreaks. Settings including the neonatal intensive care unit, endoscopy, oncology, and transplant units are areas that have specific issues which impact the approach to outbreak investigation and control. Certain organisms have a predilection for health care settings because of the illnesses of patients, the procedures performed, and the care provided. PMID:27515142

  12. About Skin-to-Skin Care (Kangaroo Care)

    Science.gov (United States)

    ... Prenatal Baby Bathing & Skin Care Breastfeeding Crying & Colic Diapers & Clothing Feeding & Nutrition Preemie Sleep Teething & Tooth Care Toddler Preschool Gradeschool Teen Young Adult Healthy Children > Ages & Stages > Baby > Preemie > About Skin- ...

  13. Managed Care Plans: Getting Good Care for Your Child

    Science.gov (United States)

    ... a Pediatrician Family Life Medical Home Health Insurance Pediatric Specialists Family Dynamics Media Work & Play Getting Involved in Your Community Healthy Children > Family Life > Medical Home > Health Insurance > Managed Care Plans: Getting Good Care for Your Child Family ...

  14. Lower Costs, Better Care- Reforming Our Health Care Delivery

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Affordable Care Act includes tools to improve the quality of health care that can also lower costs for taxpayers and patients. This means avoiding costly...

  15. Primary care patient and provider preferences for diabetes care managers

    Directory of Open Access Journals (Sweden)

    Ramona S DeJesus

    2010-06-01

    Full Text Available Ramona S DeJesus1, Kristin S Vickers2, Robert J Stroebel1, Stephen S Cha31Division of Primary Care Internal Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Psychiatry and Psychology, Mayo Clinic, MN, USA; 3Department of Biostatistics, Mayo Clinic, Rochester, MN, USAPurpose: The collaborative care model, using care managers, has been shown to be effective in achieving sustained treatment outcomes in chronic disease management. Little effort has been made to find out patient preferences for chronic disease care, hence, we conducted a study aimed at identifying these.Methods: A 20-item questionnaire, asking for patients’ and providers’ preferences and perceptions, was mailed out to 1000 randomly selected patients in Olmsted County, Minnesota, identified through a diabetes registry to have type 2 diabetes mellitus, a prototypical prevalent chronic disease. Surveys were also sent to 42 primary care providers.Results: There were 254 (25.4% patient responders and 28 (66% provider responders. The majority of patients (>70% and providers (89% expressed willingness to have various aspects of diabetes care managed by a care manager. Although 75% of providers would be comfortable expanding the care manager role to other chronic diseases, only 39.5% of patient responders would be willing to see a care manager for other chronic problems. Longer length of time from initial diagnosis of diabetes was associated with decreased patient likelihood to work with a care manager.Conclusion: Despite study limitations, such as the lack of validated measures to assess perceptions related to care management, our results suggest that patients and providers are willing to collaborate with a care manager and that both groups have similar role expectations of a care manager.Keywords: care manager, collaborative care, patient preference, diabetes care

  16. Disrupted caring attachments: implications for long-term care.

    Science.gov (United States)

    Flannery, Raymond B

    2002-01-01

    Caring attachments or social supports are the positive psychological and physical contacts and relationships between people. These attachments have been associated with improved health, well-being, and longevity. It is also true that disrupted caring attachments are associated with impaired health and well-being. This paper reviews the general medical and elder medical findings of disrupted caring attachments and negative health outcomes. The implications of these findings for dementia sufferers, caregivers, and long-term care staff are examined.

  17. Developing Integrated Care: Towards a development model for integrated care

    NARCIS (Netherlands)

    M.M.N. Minkman (Mirella)

    2012-01-01

    textabstractThe thesis adresses the phenomenon of integrated care. The implementation of integrated care for patients with a stroke or dementia is studied. Because a generic quality management model for integrated care is lacking, the study works towards building a development model for integrated c

  18. Financial Health of Child Care Facilities Affects Quality of Care.

    Science.gov (United States)

    Brower, Mary R.; Sull, Theresa M.

    2003-01-01

    Contends that child care facility owners, boards of directors, staff, and parents need to focus on financial management, as poor financial health compromises the quality of care for children. Specifically addresses the issues of: (1) concern for providing high quality child care; (2) the connection between quality and money; and (3) strengthening…

  19. Why Should We Care about Child Care? [Video].

    Science.gov (United States)

    Families and Work Inst., New York, NY.

    Produced as a touchstone for the White House Conference on Child Care, this brief video (5 minutes) presents a collage of voices speaking on the need for quality child care. The voices include those of parents, physicians and child development experts, and child care workers. Among the threads touched upon by these voices are working mothers, the…

  20. EMPLOYEE SPIRITUAL CARE: Supporting Those Who Care for Others.

    Science.gov (United States)

    McMillan, Kathleen

    2016-01-01

    In order to provide whole-person care for patients and families, Loma Linda University Health recognizes the importance of supporting employee wholeness. The Employee Spiritual Care department helps create and support an environment that nurtures the spiritual health and wholeness of employees, and provides employees tools and knowledge about providing whole-person care to patients and colleagues. PMID:27119805

  1. Taking Care of Your Vision

    Science.gov (United States)

    ... a Friend Who Cuts? Taking Care of Your Vision KidsHealth > For Teens > Taking Care of Your Vision ... are important parts of keeping your peepers perfect. Vision Basics One of the best things you can ...

  2. Communication in Cancer Care (PDQ)

    Science.gov (United States)

    ... Finished Treatment Questions to Ask About Cancer Research Communication in Cancer Care (PDQ®)–Patient Version Overview Go ... fewer procedures and better quality of life. Good communication between patients, family caregivers, and the health care ...

  3. Types of health care providers

    Science.gov (United States)

    Physicians; Nurses; Health care providers; Doctors; Pharmacists ... with a Doctor of Medicine (MD) or a Doctor of Osteopathic Medicine (DO). NURSING CARE Registered nurses (RNs) have graduated from a nursing program, have ...

  4. MCBS Access to Care PUF

    Data.gov (United States)

    U.S. Department of Health & Human Services — The MCBS 2013 Access to Care public use file (MCBS PUF) provides the first publically available MCBS file for researchers interested in the health, health care use,...

  5. Parameters of care for craniosynostosis

    DEFF Research Database (Denmark)

    Vargervik, Karin; Rubin, Marcie S; Grayson, Barry H;

    2012-01-01

    A multidisciplinary conference was convened in March 2010 with the charge to develop parameters of care for patients with craniosynostosis. The 52 participants represented 16 medical specialties and 16 professional societies. Herein, we present the dental, orthodontic, and surgical care...

  6. Customer care in the NHS.

    Science.gov (United States)

    Ruddick, Fred

    2015-01-20

    Viewing individuals in need of NHS care as customers has the potential to refocus the way their care is delivered. This article highlights some of the benefits of reframing the nurse-patient relationship in terms of customer care, and draws parallels between good customer care and the provision of high quality patient care in the NHS. It explores lessons to be learned from those who have studied the customer experience, which can be adapted to enhance the customer care experience within the health service. Developing professional expertise in the knowledge and skills that underpin good-quality interpersonal encounters is essential to improve the customer experience in health care and should be prioritised alongside the development of more technical skills. Creating a culture where emotional intelligence, caring and compassion are essential requirements for all nursing staff will improve patient satisfaction. PMID:25585766

  7. Center to Advance Palliative Care

    Science.gov (United States)

    ... Catalogue Membership Brochure Join CAPC Central Registry National Palliative Care Registry™ Enter your data to improve performance, prove ... Log In to register Billing for Community-Based Palliative Care Virtual Office Hour Anne E. Monroe, MHA October ...

  8. Understanding your health care costs

    Science.gov (United States)

    ... as X-rays or MRIs Rehab, physical or occupational therapy, or chiropractic care Mental health, behavioral health, or substance abuse care Hospice, home health, skilled nursing, or durable medical equipment Prescription drugs Dental and ...

  9. What is Pediatric Palliative Care?

    Science.gov (United States)

    ... communication and coordination of care. With the close communication that palliative care provides, families are better able to choose options that are in line with their values, traditions and culture. This improves the well-being of the entire ...

  10. Care in the Community

    Science.gov (United States)

    Brown, S.; Hine, N.; Sixsmith, A.; Garner, P.

    The UK population is ageing. At the time of the 2001 census there were 8.1 million people aged over 65 living in the UK, 3.1 million of them living alone. By 2011 the number of over 65s is projected to reach just under 12 million, and by 2026 over 13 million [1]. The extra workload this will place on health and care services will be compounded by political ambitions aimed at meeting the challenges of rising patient expectations [2]. In addition to this, the Department of Health aims to promote the independence of older people by providing enhanced services from the National Health Service (NHS) and councils to prevent unnecessary hospital admission [3]. As a result we can expect to see a continuing rise in the number of elderly people living at home and requiring good-quality health and social care services.

  11. Elderly Care Centre

    Science.gov (United States)

    Wagiman, Aliani; Haja Bava Mohidin, Hazrina; Ismail, Alice Sabrina

    2016-02-01

    The demand for elderly centre has increased tremendously abreast with the world demographic change as the number of senior citizens rose in the 21st century. This has become one of the most crucial problems of today's era. As the world progress into modernity, more and more people are occupied with daily work causing the senior citizens to lose the care that they actually need. This paper seeks to elucidate the best possible design of an elderly care centre with new approach in order to provide the best service for them by analysing their needs and suitable activities that could elevate their quality of life. All these findings will then be incorporated into design solutions so as to enhance the living environment for the elderly especially in Malaysian context.

  12. Measuring integrated care

    DEFF Research Database (Denmark)

    Strandberg-Larsen, Martin

    2011-01-01

    The positive outcomes of coordination of healthcare services are to an increasing extent becoming clear. However the complexity of the field is an inhibiting factor for vigorously designed trial studies. Conceptual clarity and a consistent theoretical frame-work are thus needed. While researchers...... respond to these needs, patients and providers face the multiple challenges of today's healthcare environment. Decision makers, planners and managers need evidence based policy options and information on the scope of the integrated care challenges they are facing. The US managed care organization Kaiser...... the multi-dimensional aspects of integrated healthcare delivery. 2) To assess the level of integration of the Danish healthcare system. 3) To assess the use of joint health plans as a tool for coordination between the regional and local level in the Danish healthcare system. 4) To compare the inputs...

  13. Pediatric cardiac postoperative care

    Directory of Open Access Journals (Sweden)

    Auler Jr. José Otávio Costa

    2002-01-01

    Full Text Available The Heart Institute of the University of São Paulo, Medical School is a referral center for the treatment of congenital heart diseases of neonates and infants. In the recent years, the excellent surgical results obtained in our institution may be in part due to modern anesthetic care and to postoperative care based on well-structured protocols. The purpose of this article is to review unique aspects of neonate cardiovascular physiology, the impact of extracorporeal circulation on postoperative evolution, and the prescription for pharmacological support of acute cardiac dysfunction based on our cardiac unit protocols. The main causes of low cardiac output after surgical correction of heart congenital disease are reviewed, and methods of treatment and support are proposed as derived from the relevant literature and our protocols.

  14. Palliative care in home care: perceptions of occupational therapists

    Directory of Open Access Journals (Sweden)

    Séfora Gomez Portela

    2015-03-01

    Full Text Available This research aimed at understanding and reflecting on the perceptions of occupational therapists regarding the implementation of palliative care in home care. This is an exploratory, qualitative study, through semi-structured interviews, conducted in the second semester of 2012 with eight occupational therapists with experience in palliative care in the city of São Paulo. Content analysis identified four themes: characterization and professional trajectory in the field, understanding the concepts of palliative care, home care and palliative care, and occupational therapy and palliative care in home care. The results suggest that the role of the occupational therapist in this field has taken place at different levels of health care, being addressed to people with varying needs. The use of the concept of palliative care by the interviewees exceeds the notion of end of life, following the changes in the epidemiological transition. They understand that professional services follow the trend of national palliative care services with focus on specialized levels, but manifest the importance of its implementation in primary and home care. Among the barriers to practice, they identified the complexity of “being at home “, peculiarities of palliative care with high cost demands, lack of infrastructure and implementation of the current policy. Professional training and scientific roduction in the area were viewed as inadequate, although they identified a call for change. The interviewees recognized palliative care in home care as a strong professional field, but one still requiring study and discussions regarding its limits and conditions of implementation, especially in the Unified Health System.

  15. Care for Dogs

    Institute of Scientific and Technical Information of China (English)

    孙犁

    2015-01-01

    <正>I choose dog issue as the starting point of my paper,for I have seen many stray dogs everywhere and also some domestic dogs have no suitable place to live,enjoy little care and have little rights.As to those stray dogs,there are many stray dogs one can see on the street.These dogs are running across roads,sidewalks even highways.Many stray dogs’dead bodies are seen on the

  16. Improving assisted living care.

    Science.gov (United States)

    Gregory, Nancy; Gesell, Sabina B; Widmer, Tom

    2007-01-01

    In the absence of a national measurement system, private vendors of satisfaction measurement and improvement services have played a crucial role in the quality movement in the assisted living industry. Survey responses from 175 resident-family dyads at 20 facilities were analyzed to identify priorities for service improvement from the customers' perspective. They include improving care provided by aides and management, meal service, and activities. Practical solutions for addressing these issues are presented.

  17. Pregnancy and care practices

    OpenAIRE

    ARÉVALO SÁNCHEZ, ELIZABETH

    2010-01-01

    The purposeofthisresearch istovalue thecarepractices that mothers perform on themselves and on the baby to whom she is going to give birth. 150 pregnant women that go to the Centro Operativo Local Engativá medical facility, registered on project 7317: "Preganant Families: healthy and desired babies of the Administrative DepartmentofSocialWellbeing", using a quantitative and descriptive methodology. We applied the "Instrument to value those care practices that are performed on themselves and o...

  18. Ambulatory Care Database

    OpenAIRE

    Misener, Terry R.

    1983-01-01

    A six month project was undertaken to collect outpatient encounter data (demographic, workload, and diagnoses) at a community medical treatment facility. To capture data, the 13,000 patients seen each month, the clerical staff and primary care providers all completed portions of a “mark sense” form. Study results, lessons learned, and a conceptual plan for a future outpatient information system are reviewed.

  19. Child Care Subsidy Programs

    OpenAIRE

    David Blau

    2000-01-01

    Child care and early education subsidies are an important part of government efforts to increase economic independence and improve development of children in low-income families in the United States. This chapter describes the main subsidy programs in the U.S., discusses economic issues that arise in designing such programs and evaluating their effects, and surveys evidence on the effects of the programs. An important theme of the chapter is the tradeoff between the policy goals of increasing...

  20. [DIE TAKING CARE].

    Science.gov (United States)

    Re, Cecilia

    2016-02-01

    Under the paradigm of complex thought, Edgar Morin and the pedagogy of the oppressed by Paulo Freire we describe and explain briefly the reasons of the squalid conditions in which develops the work of caring, which is not only an art and a science. The review of scientific literature, as well as the stories of life, support the need for a pedagogical reference change in vocational training programs.

  1. "Uberizing" home care in Ontario.

    Science.gov (United States)

    Wojtak, Anne; Stark, Linda

    2016-07-01

    This article looks at home care in Ontario and its role as a foundation for a sustainable healthcare system in the future. Beginning with the history and evolution of the service delivery model, it examines current challenges and opportunities to unleash the potential of home care within a more integrated model for patient-centred care for the future. An in-depth look at how to better coordinate, integrate, and fund care for patients is highlighted. PMID:27269814

  2. In Search of Personal Care

    OpenAIRE

    Wellin, Chris

    2016-01-01

    In addition to medical and bodily needs, personal(ized) care involves the biographical and social identity of the recipient. Care-work always requires some adaptation to individual preferences and responses. But typically this is either an implicit or a secondary feature of care. However, with chronic, cognitive illnesses such as Alzheimer’s disease, the very capacity for maintaining self (e.g., memory and language facility) is threatened, and so the extent to which care addresses the person ...

  3. Why nursing care is missed?

    OpenAIRE

    Wiwanitkit V

    2014-01-01

    Nursing care is an important part for success of clinical therapeutics and diagnosis. The problem of nursing care can be seen elsewhere. An important consideration is on missed nursing care. The common elements of missed nursing care usually lie on these scopes: “ambulation, turning, delayed or missed feedings, patient teaching, discharge planning, emotional support, hygiene, intake and output documentation, and surveillance.”

  4. HOSPITAL VARIATION IN MISSED NURSING CARE

    OpenAIRE

    Kalisch, Beatrice J.; Tschannen, Dana; Lee, Hyunhwa; Friese, Christopher R.

    2011-01-01

    Quality of nursing care across hospitals is variable, and this variation can result in poor patient outcomes. One aspect of quality nursing care is the amount of necessary care omitted. This paper reports on the extent and type of nursing care missed and the reasons for missed care. The MISSCARE Survey was administered to nursing staff (n = 4086) who provide direct patient care in ten acute care hospitals. Missed nursing care patterns, as well as reasons for missing care (labor resources, mat...

  5. Sepsis in critical care.

    Science.gov (United States)

    King, Joan E

    2007-03-01

    Sepsis is a syndrome produced by the accelerated activity of the inflammatory immune response, the clotting cascade, and endothelial damage. It is a systematic process that can progress easily into septic shock and MODS. The chemical mediators or cytokines produce a complex self-perpetuating process that impacts all body systems. It is critical for the nurse first to identify patients at risk for developing sepsis and to assess patients who have SIRS and sepsis continually for signs and symptoms of organ involvement and organ dysfunction. Once sepsis has been diagnosed, evidence-based practice indicates initiation of fluid resuscitation. Vasopressor therapy, positive inotropic support, and appropriate antibiotic therapy should be started within the first hour. Within a 6-hour timeframe the goal is stabilization of the CVP, MAP, and UOP to prevent further organ damage. The challenge for nurses caring for septic patients is to support the treatment goals, to prevent added complications including stress ulcers, DVTs, aspiration pneumonia, and the progression to MODS, and to address the patient's and the family's psychosocial needs. As complex as the pathophysiology of sepsis is, the nursing care is equally complex but also rewarding. Patients who previously might have died now recover as vigilant nursing care combines forces with new drug therapies and evidence-based practice guidelines.

  6. Music in child care

    Directory of Open Access Journals (Sweden)

    Maria Polikandrioti

    2007-07-01

    Full Text Available Music has been used therapeutically for many centuries, and numerous studies have researched the curative and preventative powers of music in several diseases. Music, as a therapy was shown to have positive effects in child care, such as in premature infants, children in emergency care, children receiving surgery, children in oncology departments and handicapped children. The aim of this review was to study the therapeutic effects of music in child care at hospital. The method οf this study included bibliography research from both the review and the research internatio nal literature, which was referred to the therapeutic effects of music in Children's Hospital. Results: Most studies focus on the beneficial effects of music to child. The results of the study showed that music is widely used to enhance well‐being and appears to exert direct effects to child, which are mainly related to physiology and psychology, including changes in the vital signs, reductions in anxiety and pain, distraction of attention from unpleasant sensations and better communication with the environment at hospital. Furthermore, music exerts indirect effects to child since is able to cause positive modifications in nurses' behaviour and conduces to better performance in their duties. Conclusions: Music consists a low-cost "therapeutic instrument" for nurses to apply to child-patient and is found to be effective in producing positive outcomes. The nurses' knowledge of music therapy need to be improved and the therapeutic impact of music must be a result from systematic professional application.

  7. Telemedicine in wound care.

    Science.gov (United States)

    Chanussot-Deprez, Caroline; Contreras-Ruiz, José

    2008-12-01

    Telemedical wound care is one of the applications of teledermatology. We present our experience using telemedicine in the successful assessment and treatment of three patients with hard-to-heal ulcers. Three patients were seen at the PEMEX General Hospital in Veracruz, Mexico. The first patient was a 53-year-old man with hypertension, morbid obesity, chronic venous insufficiency, recurrent erysipelas, leg ulcers and lymphoedema. There was one ulcer on his left lower leg (20 x 10 cm) and one on his right leg (9 x 7 cm). The second patient was a 73-year-old woman with class III obesity and ulcers in her right leg, secondary to surgical debridement of bullous erysipelas. The third patient was a 51-year-old female with rheumatoid arthritis with one ulcer on each leg and chronic lymphostasis. Photographs with a digital camera were taken and sent weekly via email to a wound care specialist in Mexico City. The photographs allowed the expert to diagnose and evaluate the chronic wounds periodically. In the present cases, telemedicine allowed us to have a rapid evaluation, diagnosis and treatment. The images were of enough quality to be useful and small enough to be sent via regular email to the remote physician who immediately gave his feedback. The expert was confident to give therapeutic recommendations in this way, and we considered this method to be very cost-effective, saving the patient and the health care system, especially in transportation. PMID:18808429

  8. Care, communication and conversation.

    Science.gov (United States)

    De Dijn, Herman

    2005-09-01

    The professionalisation of care has resulted in ever increasing specialisation, use of technical innovations and informatisation. This has had consequences for the level and way of involvement of the care provider vis-a-vis the patient. The result has been growing alienation on the part of the patient and flight into non-classical medicine, as well as frustration on the part of medical personnel, likewise with respect to the reactions of patients. A solution is usually sought in more communication. This might be styled the professional answer to alienation and frustration, whereby 'the human factor', it is hoped, can be better accounted for. Enhanced communication implies two elements: 1) to better cater for the feelings of patients by trained communicators, i.e. more openness, more client satisfaction; 2) to better take into account patient rights and to actually implement them. The question is whether measures in terms of communication, geared at enhancing client satisfaction and the implementation of patient rights, are the real answer to the above mentioned alienation and frustration. Perhaps the trouble has deeper reasons and requires taking other dimensions into account such as decency and human dignity, which cannot be captured simply in terms of satisfaction and rights. This would mean that the answer must be sought at a deeper level than communication. This level might be called 'conversation' (using a concept analysed by Michael Oakeshott). In the second part of the paper, the possible relationship between care and conversation will be briefly analysed.

  9. Access and care issues in urban urgent care clinic patients

    Directory of Open Access Journals (Sweden)

    Adams Jill C

    2009-12-01

    Full Text Available Abstract Background Although primary care should be the cornerstone of medical practice, inappropriate use of urgent care for non-urgent patients is a growing problem that has significant economic and healthcare consequences. The characteristics of patients who choose the urgent care setting, as well as the reasoning behind their decisions, is not well established. The purpose of this study was to determine the motivation behind, and characteristics of, adult patients who choose to access health care in our urgent care clinic. The relevance of understanding the motivation driving this patient population is especially pertinent given recent trends towards universal healthcare and the unclear impact it may have on the demands of urgent care. Methods We conducted a cross-sectional survey of patients seeking care at an urgent care clinic (UCC within a large acute care safety-net urban hospital over a six-week period. Survey data included demographics, social and economic information, reasons that patients chose a UCC, previous primary care exposure, reasons for delaying care, and preventive care needs. Results A total of 1, 006 patients were randomly surveyed. Twenty-five percent of patients identified Spanish as their preferred language. Fifty-four percent of patients reported choosing the UCC due to not having to make an appointment, 51.2% because it was convenient, 43.9% because of same day test results, 42.7% because of ability to get same-day medications and 15.1% because co-payment was not mandatory. Lack of a regular physician was reported by 67.9% of patients and 57.2% lacked a regular source of care. Patients reported delaying access to care for a variety of reasons. Conclusion Despite a common belief that patients seek care in the urgent care setting primarily for economic reasons, this study suggests that patients choose the urgent care setting based largely on convenience and more timely care. This information is especially applicable to

  10. The care perspective and autonomy

    NARCIS (Netherlands)

    Verkerk, M.A.

    2001-01-01

    In this article I wish to show how care ethics puts forward a fundamental critique on the ideal of independency in human life without thereby discounting autonomy as a moral value altogether. In care ethics, a relational account of autonomy is developed instead. Because care ethics is sometimes crit

  11. A better understanding of care

    NARCIS (Netherlands)

    Isolde Woittiez; Lisa Putman; Evelien Eggink; Michiel Ras

    2014-01-01

    Original title: Zorg beter begrepen Dutch government spending on care for people with an intellectual disability has been rising steeply for many years. This increase is due not so much to rising costs, but mainly to growth in demand for care. The profile of those applying for care has changed. Wher

  12. A Universal Duty to Care

    NARCIS (Netherlands)

    I.A.M. Robeyns (Ingrid)

    2011-01-01

    textabstractThe most basic and fundamental need that human beings have is the need to be properly cared for. Already before their birth, human beings need proper care, for example by being provided with the right nutrition, not being exposed to toxics, and receiving the right professional care to ch

  13. Information Sharing for Care Coordination

    OpenAIRE

    Amir, Ofra; Grosz, Barbara J.; Stern, Roni; Sanders, Lee M.

    2013-01-01

    Teamwork and care coordination are of increasing importance to health care delivery and patient safety and health. This paper describes our initial work on developing agents that are able to make intelligent information sharing decisions to support a diverse, evolving team of care providers in constructing and maintaining a shared plan that operates in uncertain environments and over a long time horizon.

  14. Taking Care of Your Teeth

    Science.gov (United States)

    ... teeth are important in many ways. If you take care of them, they'll help take care of you. Strong, healthy teeth help you chew ... have some baby teeth? If you don't take care of your teeth, cavities and unhealthy gums will ...

  15. Illinois: Child Care Collaboration Program

    Science.gov (United States)

    Center for Law and Social Policy, Inc. (CLASP), 2012

    2012-01-01

    The Illinois Child Care Collaboration Program promotes collaboration between child care and other early care and education providers, including Early Head Start (EHS), by creating policies to ease blending of funds to extend the day or year of existing services. While no funding is provided through the initiative, participating programs may take…

  16. Elder Care Comes of Age.

    Science.gov (United States)

    Herndon, Mary D.

    1995-01-01

    A discussion of elder care looks at the extent to which government and employers are addressing the issue, how elder care affects the work performance of and productivity of employed caregivers, and how human resource professionals can respond effectively to the needs of both employee and employer as these needs relate to the issue of elder care.…

  17. CURRICULUM GUIDE, CHILD CARE CENTERS.

    Science.gov (United States)

    California State Dept. of Education, Sacramento.

    CALIFORNIA CHILD CARE CENTERS WERE ESTABLISHED IN 1943 TO SUPPLY SERVICES TO CHILDREN OF WORKING MOTHERS. THE CHILD CARE PROGRAM PROVIDES, WITHIN NURSERY AND SCHOOLAGE CENTERS, CARE AND EDUCATIONAL SUPERVISION FOR PRESCHOOL AND ELEMENTARY SCHOOL AGE CHILDREN. THE PHILOSOPHY OF THE CHILD CENTER PROGRAM IS BASED UPON THE BELIEF THAT EACH CHILD…

  18. Primary Medical Care in Chile

    DEFF Research Database (Denmark)

    Scarpaci, Joseph L.

    Primary medical care in Chile: accessibility under military rule [Front Cover] [Front Matter] [Title Page] Contents Tables Figures Preface Chapter 1: Introduction Chapter 2: The Restructuring of Medical Care Financing in Chile Chapter 3: Inflation and Medical Care Accessibility Chapter 4: Help...

  19. BIOLOGICAL CHARACTERISTICS OF FUSARIUM GRAMINEARUM SCHW. AND FUSARIUM CULMORUM (W.G. SMITH SACC.

    Directory of Open Access Journals (Sweden)

    Jasenka Ćosić

    2006-12-01

    Full Text Available Fusarium species from section Discolor are widespread and well-known and play an important role in disease etiology of wheat, barley and maize. F. graminearum and F. culmorum were isolated during a four-year period at several locations in Eastern Croatia and from different hosts. The mycelium development of 236isolates of F. graminearum and 2 isolates of F. culmorum was cultered during an eight day period on water agar, PDA, Bilai, Czapek's and CLA agar at temperatures 5°, 15°, 20°, 25° and 30°C and a 12 hour dark/light regime. The results show that agar medium does not influence colony diameter significantly. The agar medium influences the richness and density of the aerial mycelium significantly, although the shape and compactness of the mycelium is not only the result of the medium on which the fungus is developed, but also of the characteristics of the species itself. The sporulation of F. culmorum was abundant on all investigated medium, whereas the sporulation of F. graminearum was very weak on PDA and Bilai agar and it was medium on CLA.

  20. Induced mutations to develop sources of resistance to rice blast, Pyricularia grisea Sacc

    International Nuclear Information System (INIS)

    Rice blast caused by Pyricularia grisea is the most important disease limiting yields worldwide. The pathogen has many virulent forms or pathotypes, hence durable blast resistance is lacking. Studies on strategy to develop durable blast resistance based on defining the genetic structure of the population, using DNA-fingerprinting, and virulence diversity are described. This strategy is leading to the identification of resistance genes/sources against all isolates within a genetic family of the pathogen. Combinations of genes showing complementary resistance to different genetic families of the fungus exclude any compatible interaction with a blast isolate. Identification of complementary resistance genes is based on detecting those virulence factors whose combinations in individual isolates within the pathogen population have a frequency near zero. Identifying and combining resistance genes to which combinations of corresponding virulence genes are absent in the pathogen population should confer more durable resistance than that previously obtained. The use of induced mutations in the development of resistance was limited, since in most cases single gene changes were responsible for the induced resistance against all the pathogen population. The main objective here is to develop many mutants, each with a gene resistant to just one or a few families of the blast pathogen; and crossing them can accumulate the different resistance genes. A total of 201 Latin American commercial cultivars, including Cuban, Brazilian and Venezuelan were analyzed with different genetic families of the blast pathogen to identify potential sources of resistance to blast and identify complementary resistance sources. Characterization of the resistance of 37 mutants of the Colombian rice cultivar Oryzica 1 was conducted in collaboration with the INEA in Colombia. Results suggested that mutations for resistance to genetic families to which Oryzica 1 is susceptible were induced, although one isolate in the most common genetic family (SRL-6) of the pathogen was compatible with all mutants. These results suggest that a larger population of mutants is needed to increase the probability of identifying a gene resistant to all members of this family; and that mutations in a variety, initially resistant to this genetic family (SRL-6) but susceptible to a different family, could have better probability of success. Seven additional commercial rice cultivars from Colombia were irradiated and selection of mutants, differing in their resistance to the different genetic families of the pathogen has been conducted during 1997 and 1998. Several different resistant mutants have been selected and will be used in crosses to combine the various resistance genes. (author)

  1. Influence of epiphytic bacteria from grapevine leaves on Phomopsis viticola Sacc.

    Directory of Open Access Journals (Sweden)

    Ewa Król

    2013-12-01

    Full Text Available Out of 282 isolates of epiphytic bacteria population originating from grapevine leaves 15% inhibited growth of Phomopsis viticola on potato-dextrose agar. Protective activity of 16 isolates, representing different morphological groups was tested on one-year old of grapevine stems fragments. Majority of bacterial isolates which inhibited the fungus growth in-vitro provided no protection of stems fragments against P. viticola. The efficiency of protection activity of bacterial isolates tested decreased with time. The most effective isolates of bacteria in protection of grapevine stemswere identified as Bacillus sp. and Pseudomonas fluorescens.

  2. The Effect of Nanosilver on Pigments Production by Fusarium culmorum (W. G. Sm.) Sacc

    DEFF Research Database (Denmark)

    Kasprowicz, Marek J.; Gorczyca, Anna; Frandsen, Rasmus John Normand

    2013-01-01

    levels. The performed analysis of metabolites indicates that under the influence of nanosilver fungi biosynthesise aurofusarin more intensively and the conversion of rubrofusarin to aurofusarin is intensified as compared to the control culture. Under the influence of nanosilver F culmorum intensively...... biosynthesises an unidentified dye which shares structural features with aurofusarin but which is not produced by fungi in standard cultures....

  3. ANTIFUNGAL ACTIVITY OF CHITOSAN AND ONE OF ITS HYDROLYSATES ON Pyricularia grisea, Sacc. FUNGUS

    Directory of Open Access Journals (Sweden)

    Aida T. Rodríguez

    2003-01-01

    Full Text Available La quitosana y sus derivados reducen marcadamente el crecimiento micelial de algunos hongos con un mayor efecto inhibitorio a elevadas concentraciones. El efecto fungistático y fungicida in vitro de la quitosana y el hidrolizado de quitosana fue investigado sobre el hongo Pyricularia grisea. El experimento se realizó en el laboratorio de Microbiología del Departamento de Fisiología y Bioquímica Vegetal del Instituto Nacional de Ciencias Agrícolas (INCA. Se encontró que ambos principios activos reducen el crecimiento radial del micelio del hongo con diferencias significativas entre los tratamientos. Las mejores concentraciones utilizadas fueron 1000 mg.L-1 para la quitosana, 500 y 1000 mg.L-1 para el hidrolizado de quitosana, pues en todas las evaluaciones realizadas se observó total inhibición. Además, se demostró el efecto biocida de estas concentraciones.

  4. ROOT ROT OF CHILLI INCITED BY Sclerotium rolfsii Sacc. AND ITS MANAGEMENT- A REVIEW

    Directory of Open Access Journals (Sweden)

    V.Madhuri

    2014-02-01

    Full Text Available Chilli (Capsicum annum L. belongs to the family solanaceae is mainly cultivated for its vegetable green fruits and dry chilli as the spice. It is believed to be originated from South America. It is a rich source of Vitamin C, A and B. Chilli is valued for pungency which is imparted by an alkaloid, Capsaicin and the red pigments (Capsanthin, Capsorubin and Capxanthin. Chillies are widely used as spice, condiment, culinary, supplement, medicine, vegetable and are ornamental plants too. It is an important food flavouring ingredientfor flavouring many vegetarian and non-vegetarian food products. In view of its multifarious uses, the demand for chillies has been on the increase world over. In India it is an important cash crop, which is grown for the domestic market and for export. In India, chillies are grown in almost all states of the country and the major growing states in terms of production are Andhra Pradesh, Karnataka, Orissa, Maharashtra, West Bengal, Rajasthan and Tamil Nadu. There are several varieties of chilli cultivated in India. The most popular among these are, Sannam, LC334, Byadagi, Wonderhot, Jwala etc. The crop suffers from many diseases like damping off, anthracnose or fruit rot or dieback, wilt, leaf spots and powdery mildew. Among the fungal diseases, root rot of chilli caused by Sclerotium rolfsii has attained the economic importance. In recent years, this disease is causing the economic losses in chillies crop (Kalmesh and Gurjar 2001.

  5. Algunas citas recientes de especies del género Phoma Sacc. en Catalunya

    OpenAIRE

    Nadal i Puigdefabregas, Martí

    1991-01-01

    Se citan 14 táxones del género Phoma (Ph. cava, Ph. epicoccinu, Ph. exigua, Ph.exigua var. foveata, Ph. glomerata, Ph. hedericola, Ph. herbarum, Ph. jolyana, Ph. leveillei, Ph. lycopersici, Ph. macrostoma, Ph. medicaginis var. pinodella, Ph. pomorum y Ph.tracheiphila). Para cada uno de los táxones se indica la fecha de recolección y la especie vegetal sobre la cual se desarrollaba. On cite 14 taxons du genre Phoma (Ph. cava, Ph. epicoccina, Ph. exigua, Ph.exigua var. foveata, Ph. glomerata...

  6. Phomopsis vexans (Sacc. & Syd. Harter: Current Research and Future Perspectives (1914-2015

    Directory of Open Access Journals (Sweden)

    Mahadevakumar S

    2016-06-01

    Full Text Available Phomopsis vexans is an important fungal plant pathogen associated with brinjal. Since its discovery from 1893, it has undergone several taxonomic changes to its current nomenclature P. vexans in 1914. Several mycologists have contributed immensely to the understanding of the diversity, biology and pathological aspects of P. vexans and to the extent to which it causes damage to the brinjal crop production. At present, P. vexans is widely distributed in all major brinjal growing regions of the world. It causes damping-off of seedlings in nursery, leaf blight; fruit rot and stem blight at various stages of plant growth and development. It produces two types of conidia such as alpha and beta; alpha conidia are hyaline, biguttulate, oval and infective and beta conidia are the diagnostic feature of the genus Phomopsis. The fungal pathogen is known to survive in soil, seed and disseminated through rain splash. Though various chemical and biological management methods have been adapted to reduce the disease incidence, P. vexans is still a major challenge for the plant pathologists around the globe. Search for various sources of resistance against P. vexans is an on-going program in many research institutes met with little success. The present management system focuses on the application of bio-control agents to check the disease development and to confer resistance against P. vexans.

  7. Diplonine, a neurotoxin isolated from cultures of the fungus Stenocarpella maydis (Berk.) Sacc. that induces diplodiosis.

    Science.gov (United States)

    Snyman, Leendert D; Kellerman, T Stephanus; Vleggaar, Robert; Flett, Bradley C; Basson, Karin M; Schultz, R Anitra

    2011-08-24

    Diplodiosis is a neuromycotoxicosis of cattle and sheep caused by ingestion of maize infected with the ear-rot fungus Stenocarpella (= Diplodia ) maydis . Apart from ataxia, paresis, and paralysis, the toxin is responsible for stillbirths and neonatal losses characterized by the presence of spongiform degeneration in the white matter of the brain in the offspring of dams exposed to infected maize cobs. In the present study a toxin, named diplonine, which induced neurological signs in guinea pigs resembling some of those occurring in cattle and sheep, was isolated from S. maydis cultures. Purification of diplonine was achieved by methanol extraction followed by chromatographic separation on silica gel and RP-18 stationary phases. The structure and relative configuration of diplonine were defined by analysis of NMR and MS data as (S)-2-amino-2-[(1R,2S)-1-hydroxy-2-methylcyclopropyl]acetic acid or the (S)-2-amino-2-[(1S,2R)-diastereomer. PMID:21780820

  8. REVIEW OF FOCUSSED ANTENATAL CARE

    Directory of Open Access Journals (Sweden)

    Sreelatha

    2015-09-01

    Full Text Available INTRODUCTION: Antenatal care is a comprehensive antepartum programme which involves a coordinated approach to medical care , continuous risk assessment , and psychological support that optimally begins before conception and extends throughout the postpartum period and int erconceptional period . [1] One of major responsibility of obstetrician providing antenatal care is to identify high risk factors based on past history, examination and investigation results. The objective of antenatal care therefore is to assure that every wanted pregnancy results in the delivery of a healthy baby without impairing the mothers health . [2] In a 1914 study by Williams antenatal care reduced fetal mortality by 40%

  9. Concept of Care, Caring Expectations, and Caring Frustrations of the Elderly Suffering from Chronic Illness

    Science.gov (United States)

    de Guzman, Allan B.; Santos, Charisse Izobelle Q.; Santos, Ivan Benedict A.; Santos, Jedda A.; Santos, Justin E.; Santos, Justo Martin S.; Santos, Vincent Emmanuelle E.

    2012-01-01

    While it is true that elderly concepts of care and caring expectations have been ascertained in previous literatures, little is known about how the elderly population views caring frustrations--particularly that of the Filipino elderly. This study purports to surface the lebenswelt of healthcare expectations and frustrations based on the…

  10. Beyond Care Avoidance and Care Paralysis : Theorizing Public Mental Health Care

    NARCIS (Netherlands)

    Schout, Gert; de Jong, Gideon; Zeelen, Jacques

    2011-01-01

    Care avoidance refers to the condition wherein clients do not seek assistance and do not attend appointments although they are in need of help. Care avoidance is linked to another phenomenon, the inability to help clients with multiple and complex problems by social services and care facilities, in

  11. Headache care in China.

    Science.gov (United States)

    Yu, Shengyuan; Zhang, Mingjie; Zhou, Jiying; Liu, Ruozhuo; Wan, Qi; Li, Yansheng

    2014-04-01

    Headache disorders are problematic worldwide. China is no different. A population-based door-to-door survey revealed that the 1-year prevalence of primary headache disorders in China was 23.8%, constituting a major societal burden. Many headache centers and clinics have been established in China, and headache disorders (and associated stress) are receiving an increased level of expert attention. This review summarizes the outcomes of the epidemiological survey and the progress of clinical and basic research in China, describes the present situation in terms of headache diagnosis and treatment, and discusses the future of headache care in China.

  12. Inverted Pyramid of Care.

    Science.gov (United States)

    Sonek, Jiri D; Kagan, Karl Oliver; Nicolaides, Kypros H

    2016-06-01

    First-trimester pregnancy evaluation using fetal and maternal parameters not only allows for diagnoses to be made early in gestation but can also assess the risk of complications that become clinically evident later in pregnancy. This evaluation makes it possible for pregnancy care to be individualized. In select cases, treatment that reduces the risk of complications can be started early in pregnancy. Even though cell free DNA is a significant advance in diagnosing fetal aneuploidy, the combination of first-trimester ultrasound and maternal serum biochemistries casts a much wider diagnostic net; therefore, the 2 technologies are best used in combination.

  13. Betting against health care.

    Science.gov (United States)

    Appleby, C

    1996-06-20

    Health care firms of all types helped fuel the biggest short-selling frenzy in the New York Stock Exchange's history, recently hitting a record 2.2 billion shares. While some analysts say this means nothing, the fact is that many investors are "shorting" the stock; in other words, they're betting against it. What appears as a lack of confidence may be nothing more than a simple quirk of Wall Street. Good, bad or indifferent, selling short is no tall tale.

  14. Health care engineering

    CERN Document Server

    Frize, Monique

    2013-01-01

    Part II of Health Care Engineering begins with statistics on the occurrence of medical errors and adverse events, and includes some technological solutions. A chapter on electronic medical records follows. The knowledge management process divided into four steps is described; this includes a discussion on data acquisition, storage, and retrieval. The next two chapters discuss the other three steps of the knowledge management process (knowledge discovery, knowledge translation, knowledge integration and sharing). The last chapter briefly discusses usability studies and clinical trials.This two-

  15. Recognition as care

    DEFF Research Database (Denmark)

    Ahlmark, Nanna; Whyte, Susan Reynolds; Harting, Janneke;

    2014-01-01

    meaningful benefits; these centred on reducing isolation and being met on their own terms regarding language and logistics. Most importantly, they remembered when treated with attention and respect by professionals and the mutual acknowledgement between participants. We use Axel Honneth’s notions of rights......-based and solidarity-based recognition to analyse what was at stake in these experiences, and we engage Annemarie Mol’s concept of a logic of care to show how recognition unfolded practically during the training. We propose that participants’ wider social context and experiences of misrecognition situated the training...

  16. Social Public Care Ahead

    Institute of Scientific and Technical Information of China (English)

    Guo Liqin

    2008-01-01

    @@ China faces toughest after-quake reconstruction since 1976. In contrast with neighbouring Myanmar's lethargic and secre-tive handling of its cyclone ten days earlier, China responded to the earthquake rapidly and with uncharacteristic openness. Within hours Premier Wen Jiabao was on a plane, and appeared in almost all the strategic plac-es in the earthquake-hit areas in the follow-ing days; President Hu Jintao was chairing an emergency meeting of Standing Com-mittee and thousands of soldiers and police were being dispatched. China is moved and moves. For the most impressive time, we read the social care from all works of lives.

  17. American Academy of Home Care Medicine

    Science.gov (United States)

    ... Newsletter Certification/Training Donate Featured Members Home Care Medicine in America The American Academy of Home Care ... Resources with the American Academy of Home Care Medicine. The American Academy of Home Care Medicine understands ...

  18. Caring for muscle spasticity or spasms

    Science.gov (United States)

    High muscle tone - care; Increased muscle tension - care; Upper motor neuron syndrome - care; Muscle stiffness - care ... can do. These stretches will help keep your muscles from getting shorter or tighter. Being active also ...

  19. What Is a Pediatric Critical Care Specialist?

    Science.gov (United States)

    ... in a pediatric intensive care unit (PICU). Pediatric critical care specialists coordinate the care of these children which is provided by a team of doctors, nurses, and other health care specialists. They use the ...

  20. Diabetes - taking care of your feet

    Science.gov (United States)

    Diabetes - foot care - self-care; Diabetic foot ulcer - foot care; Diabetic neuropathy - foot care ... Diabetes can damage the nerves and blood vessels in your feet. This damage can cause numbness and ...

  1. Child Health USA 2013: Prenatal Care Utilization

    Science.gov (United States)

    ... Health Services Utilization > Prenatal Care Utilization Prenatal Care Utilization Narrative Early and adequate prenatal care helps to ... 20.3 6.0 Adequacy of Prenatal Care Utilization Upon Initiation, * by Maternal Race/Ethnicity, 2011 Race/ ...

  2. Intercultural caring-an abductive model.

    Science.gov (United States)

    Wikberg, Anita; Eriksson, Katie

    2008-09-01

    The aim of this study was to increase the understanding of caring from a transcultural perspective and to develop the first outline of a theory. The theoretical perspective includes Eriksson's theory of caritative caring. Texts on caring by the transcultural theorists, including Campinha-Bacote, Kim-Godwin, Leininger and Ray, are analysed using content analysis. The overall theme that resulted from this analysis was that caring is a complex whole. Three main categories of caring emerged: inner caring, outer caring and the goal of caring. Inner caring consists of caring is a relationship, and caring and culture are seen in different dimensions. Outer caring refers to caring affected by educational, administrative and social and other structures. The goal of caring consists of caring leading to change towards health and well-being. The main categories include categories and subcategories that are compared with Eriksson's theory of caritative caring. A model for intercultural caring is generated abductively. Caring and culture appear in three dimensions: caring as ontology independent of context; caring as a phenomenon emphasised differently in different cultures; caring as nursing care activities is unique. Caring alleviates suffering and leads to health and well-being. This model describes caring from an intercultural perspective as a mutual but asymmetric relationship between the nurse and the patient, including the patient's family and community. The patient's cultural background and acculturation influence caring. The cultural background, cultural competence and organisation of the nurse also influence caring. Caring is seen as a complex whole. This study integrates Campinha-Bacote's, Kim-Godwin's, Leininger's and Ray's views of caring with Eriksson's caritative caring and presents caring from a transcultural perspective in a new way as a model for intercultural caring, which can benefit nursing care, education, research and administration. PMID:18840233

  3. Intercultural caring-an abductive model.

    Science.gov (United States)

    Wikberg, Anita; Eriksson, Katie

    2008-09-01

    The aim of this study was to increase the understanding of caring from a transcultural perspective and to develop the first outline of a theory. The theoretical perspective includes Eriksson's theory of caritative caring. Texts on caring by the transcultural theorists, including Campinha-Bacote, Kim-Godwin, Leininger and Ray, are analysed using content analysis. The overall theme that resulted from this analysis was that caring is a complex whole. Three main categories of caring emerged: inner caring, outer caring and the goal of caring. Inner caring consists of caring is a relationship, and caring and culture are seen in different dimensions. Outer caring refers to caring affected by educational, administrative and social and other structures. The goal of caring consists of caring leading to change towards health and well-being. The main categories include categories and subcategories that are compared with Eriksson's theory of caritative caring. A model for intercultural caring is generated abductively. Caring and culture appear in three dimensions: caring as ontology independent of context; caring as a phenomenon emphasised differently in different cultures; caring as nursing care activities is unique. Caring alleviates suffering and leads to health and well-being. This model describes caring from an intercultural perspective as a mutual but asymmetric relationship between the nurse and the patient, including the patient's family and community. The patient's cultural background and acculturation influence caring. The cultural background, cultural competence and organisation of the nurse also influence caring. Caring is seen as a complex whole. This study integrates Campinha-Bacote's, Kim-Godwin's, Leininger's and Ray's views of caring with Eriksson's caritative caring and presents caring from a transcultural perspective in a new way as a model for intercultural caring, which can benefit nursing care, education, research and administration.

  4. Symptom management in palliative care and end of life care.

    Science.gov (United States)

    Bookbinder, Marilyn; McHugh, Marlene E

    2010-09-01

    There is a need for generalist- and specialist-level palliative care clinicians proficient in symptom management and care coordination. Major factors contributing to this need include changed disease processes and trajectories, improved medical techniques and diagnostic testing, successful screening for chronic conditions, and drugs that often prolong life. The rapid progressive illnesses and deaths that plagued the first half of the twentieth century have been replaced in the twenty-first century by increased survival rates. Conditions that require ongoing medical care beyond a year define the current chronic illness population. Long years of survival are often accompanied by a reduced quality of life that requires more medical and nursing care and longer home care. This article reviews the management of selected symptoms in palliative and end of life care.

  5. Flourishing in Health Care.

    Science.gov (United States)

    Edgar, Andrew; Pattison, Stephen

    2016-06-01

    The purpose of this paper is to offer an account of 'flourishing' that is relevant to health care provision, both in terms of the flourishing of the individual patient and carer, and in terms of the flourishing of the caring institution. It is argued that, unlike related concepts such as 'happiness', 'well-being' or 'quality of life', 'flourishing' uniquely has the power to capture the importance of the vulnerability of human being. Drawing on the likes of Heidegger and Nussbaum, it is argued that humans are at once beings who are autonomous and thereby capable of making sense of their lives, but also subject to the contingencies of their bodies and environments. To flourish requires that one engages, imaginatively and creatively, with those contingencies. The experience of illness, highlighting the vulnerability of the human being, thereby becomes an important experience, stimulating reflection in order to make sense of one's life as a narrative. To flourish, it is argued, is to tell a story of one's life, realistically engaging with vulnerability and suffering, and thus creating a framework through which one can meaningful and constructively go on with one's life. PMID:26846370

  6. Managing acute care.

    Science.gov (United States)

    Russell, J S

    1993-02-01

    In the last few years, much medical-facility construction has been driven by what insurers want. Hospitals have built facilities for well-reimbursed procedures and closed money-losing ones. Health-maintenance organizations increasingly expect to hold down costs by making prepayment arrangements with doctors and their hospitals. President Clinton has pledged early action on health-care reform, which will likely change planners' priorities. Whether the nation goes to Clintonian "managed competition" or a Canadian-style nationwide single-payer system (the two most likely options), the projects on these pages reflect two large-scale trends that are likely to continue: the movement of more procedures from inpatient to outpatient facilities and the separation of treatment functions from ordinary office and administrative tasks so that the latter are not performed in the same high-cost buildings as technology-intensive procedures. Various schemes that make care more "patient-centered" have been tried and been shown to speed healing, even for outpatients, but such hard-to-quantify issues get short shrift in an era of knee-jerk cost containment. The challenge in tomorrow's healthcare universe--whatever it becomes--will be to keep these issues on the table.

  7. Modern community care program

    International Nuclear Information System (INIS)

    Going into the next millennium do we see nuclear energy? Yes we will see an expanding nuclear sector in the modem community. he modem community that cares for people, health and environment needs nuclear. Energy saves lives. Electricity is efficient use of energy. Energy will be the key to a sustainable society, energy is life. Nuclear energy protects the environment. Nuclear is an integral part of the modern community caring for people, health and environment. The dynamics of the public opinion-forming process and its effects on the nuclear industry are a challenge of the global nuclear industry. Current communications strategy and its consequences are on of the key issues. The nuclear industry must be perceived in certain ways in order to move towards achieving the vision and avoiding the harassment scenario. Each perception goal does not bear the same function within the communications process. As the nuclear industry is oe of the keys to a sustainable society, it must achieve legitimacy in its capacity as an interesting agenda-setter for tackling problems and as an expert. We have to build our communication activities on an open and honest attitude and we have to establish trust and confidence. The nuclear industry must also prove its ability and performance. If this could be achieved there will be an option for the future

  8. Critical issues in burn care.

    Science.gov (United States)

    Holmes, James H

    2008-01-01

    Burn care, especially for serious burn injuries, represents a considerable challenge for the healthcare system. The American Burn Association has established a number of strategies for the management of burn patients and dedicates its efforts and resources to promoting and supporting burn-related research, education, care, rehabilitation, and prevention, often in collaboration with other organizations. The American Burn Association has recommended that patients with serious burns be referred to a designated burn center, ie, a hospital outfitted with specialized personnel and equipment dedicated to burn care. Burn centers have been operational for over 50 years, but the complexity and costs of providing specialized burn care have given rise to a number of critical administrative and political issues. These include logistical limitations imposed by the uneven national distribution of burn centers and a potential shortage of burn beds, both during everyday conditions and in the event of a mass disaster. Burn surgeon shortages have also been identified, stemming, in part, from a lack of specialized burn care training opportunities. There is currently a lack of quality outcome data to support evidence-based recommendations for burn care, and burn care centers are compromised by problems obtaining reimbursement for the care of uninsured and publicly insured out-of-state burn patients. Initiatives are underway to maintain efficient burn care facilities that are fully funded, easily accessible, and most importantly, provide optimal, evidence-based care on a daily basis, and are well-equipped to handle a surge of patients during a disaster situation.

  9. Primary care patient and provider preferences for diabetes care managers

    OpenAIRE

    DeJesus, Ramona

    2010-01-01

    Ramona S DeJesus1, Kristin S Vickers2, Robert J Stroebel1, Stephen S Cha31Division of Primary Care Internal Medicine, Mayo Clinic, Rochester, MN, USA; 2Department of Psychiatry and Psychology, Mayo Clinic, MN, USA; 3Department of Biostatistics, Mayo Clinic, Rochester, MN, USAPurpose: The collaborative care model, using care managers, has been shown to be effective in achieving sustained treatment outcomes in chronic disease management. Little effort has been made to find out patient preferenc...

  10. Critical Care Glucose Point-of-Care Testing.

    Science.gov (United States)

    Narla, S N; Jones, M; Hermayer, K L; Zhu, Y

    2016-01-01

    Maintaining blood glucose concentration within an acceptable range is a goal for patients with diabetes mellitus. Point-of-care glucose meters initially designed for home self-monitoring in patients with diabetes have been widely used in the hospital settings because of ease of use and quick reporting of blood glucose information. They are not only utilized for the general inpatient population but also for critically ill patients. Many factors affect the accuracy of point-of-care glucose testing, particularly in critical care settings. Inaccurate blood glucose information can result in unsafe insulin delivery which causes poor glucose control and can be fatal. Healthcare professionals should be aware of the limitations of point-of-care glucose testing. This chapter will first introduce glucose regulation in diabetes mellitus, hyperglycemia/hypoglycemia in the intensive care unit, importance of glucose control in critical care patients, and pathophysiological variables of critically ill patients that affect the accuracy of point-of-care glucose testing. Then, we will discuss currently available point-of-care glucose meters and preanalytical, analytical, and postanalytical sources of variation and error in point-of-care glucose testing. PMID:27645817

  11. Palliative Care as a Standard of Care in Pediatric Oncology.

    Science.gov (United States)

    Weaver, Meaghann S; Heinze, Katherine E; Kelly, Katherine P; Wiener, Lori; Casey, Robert L; Bell, Cynthia J; Wolfe, Joanne; Garee, Amy M; Watson, Anne; Hinds, Pamela S

    2015-12-01

    The study team conducted a systematic review of pediatric and adolescent palliative cancer care literature from 1995 to 2015 using four databases to inform development of a palliative care psychosocial standard. A total of 209 papers were reviewed with inclusion of 73 papers for final synthesis. Revealed topics of urgent consideration include the following: symptom assessment and intervention, direct patient report, effective communication, and shared decision-making. Standardization of palliative care assessments and interventions in pediatric oncology has the potential to foster improved quality of care across the cancer trajectory for children and adolescents with cancer and their family members.

  12. Coordinating Care for Children with Special Health Care Needs

    OpenAIRE

    Stephanie Peterson; Shanna Shulman; Henry Ireys

    2007-01-01

    This brief, the fourth in a series on critical issues involved in caring for children with special health care needs, notes that nearly three-quarters of parents who need professional care coordination services for their child say they do not get enough help—if they get any at all. Moreover, one-third of those who do get help are not fully satisfied with the quality of services they receive. Although many health plans coordinate care for their adult members with chronic conditions and disab...

  13. Diabetes care provision in UK primary care practices.

    Directory of Open Access Journals (Sweden)

    Gillian Hawthorne

    Full Text Available BACKGROUND: Although most people with Type 2 diabetes receive their diabetes care in primary care, only a limited amount is known about the quality of diabetes care in this setting. We investigated the provision and receipt of diabetes care delivered in UK primary care. METHODS: Postal surveys with all healthcare professionals and a random sample of 100 patients with Type 2 diabetes from 99 UK primary care practices. RESULTS: 326/361 (90.3% doctors, 163/186 (87.6% nurses and 3591 patients (41.8% returned a questionnaire. Clinicians reported giving advice about lifestyle behaviours (e.g. 88% would routinely advise about calorie restriction; 99.6% about increasing exercise more often than patients reported having received it (43% and 42% and correlations between clinician and patient report were low. Patients' reported levels of confidence about managing their diabetes were moderately high; a median (range of 21% (3% to 39% of patients reporting being not confident about various areas of diabetes self-management. CONCLUSIONS: Primary care practices have organisational structures in place and are, as judged by routine quality indicators, delivering high quality care. There remain evidence-practice gaps in the care provided and in the self confidence that patients have for key aspects of self management and further research is needed to address these issues. Future research should use robust designs and appropriately designed studies to investigate how best to improve this situation.

  14. Oral Health Care in Home Care Service – Personnels’ Perspective

    OpenAIRE

    Lundqvist, Pontus; Mathson, Anton

    2014-01-01

    Elderly nowadays stay longer in their own home. This raises the standards on home care service to contribute to the maintenance of elderly’s general and oral health. Our objective is therefore to explore attitudes about how home care workers view oral health care and the importance of good oral health for elderly clients. 8 subjects (22 to 61 years of age) were selected for the study working in home care service, which all gave their informed consent. Semi-structured interviews were performed...

  15. Transitional Care: A Priority for Health Care Organizational Ethics.

    Science.gov (United States)

    Naylor, Mary; Berlinger, Nancy

    2016-09-01

    Numerous studies have revealed that health care transitions for chronically ill older adults are frequently poorly managed, often with devastating human and economic consequences. And poorly managed transitions and their consequences also occur among younger, relatively healthy individuals who have adequate resources and are prepared to advocate on their own behalf. Despite the rich base of research confirming that evidence-based transitional care enhances patients' experiences, improves health and quality of life, and reduces costs, organizational, regulatory, financial, and cultural barriers have, until recently, prevented widespread adoption of these proven approaches. Provisions of the Affordable Care Act, such as reductions in Medicare payments to hospitals with very high thirty-day rehospitalization rates, have reduced barriers, but uptake of evidence-based transitional care beyond demonstration projects continues to be sporadic and far too slow. With a rich understanding about how to better anticipate and respond to the compelling problems experienced by patients, family caregivers, and health care professionals throughout episodes of acute illness, the time has come to frame transitional care as a system's ethical responsibility in an aging society. Embedding transitional care within the ethical obligations of a health care system requires the perspectives and involvement of nurses and nursing because of this profession's integral role in every aspect of care transitions. PMID:27649919

  16. Generalist palliative care in hospital

    DEFF Research Database (Denmark)

    Bergenholtz, Heidi; Jarlbæk, Lene; Hølge-Hazelton, Bibi

    2016-01-01

    Background: It can be challenging to provide generalist palliative care in hospitals, owing to difficulties in integrating disease-orientedtreatment with palliative care and the influences of cultural and organisational conditions. However, knowledge on the interactionsthat occur is sparse. Aim......: To investigate the interactions between organisation and culture as conditions for integrated palliative care in hospital and, ifpossible, to suggest workable solutions for the provision of generalist palliative care. Design: A convergent parallel mixed-methods design was chosen using two independent studies...... hospital with 29 department managements and one hospital management. Results: Two overall themes emerged: (1) ‘generalist palliative care as a priority at the hospital’, suggesting contrasting issues regardingprioritisation of palliative care at different organisational levels, and (2) ‘knowledge and use...

  17. Standard of care in dentistry

    Directory of Open Access Journals (Sweden)

    Gokul Sridharan

    2012-01-01

    Full Text Available Medical ethics is primarily a field of applied ethics, the study of moral values and judgments as applicable to medicine. Dental practitioners constitute a group of health professionals who deal with human health care on a regular basis. Various ethical principles govern their conduct and their approach toward the patients. Ethical code of conduct prescribes a minimum standard of care which is applicable to all dental professionals. Substandard dental care is unacceptable and mounts to negligence on the part of the professional. Knowledge on what constitutes standard of care is a pre-requisite for dental professionals in providing quality health care. This paper presents a brief overview on standard of care as applicable to dentist and its practical implications with a note on the legal issues pertaining to medical negligence as applicable in India.

  18. Inter-Professional Palliative Care

    DEFF Research Database (Denmark)

    Madsen, Kirsten Halskov; Henriksen, Jette; Meldgaard, Anette

    2013-01-01

    Chapter 11 by Kirsten Halskov Madsen, Anette Meldgaard and Jette Henriksen deals with the development of palliative care programmes aimed at the basic level of palliative care practice. The need to develop educational opportunities at particularly this level – described as ‘the basic inter......-professional level of palliative care’ – has been increasing for many years where palliative care has conventionally and primarily been associated with specialist training. As the authors show – based on a mapping out of existing educational initiatives in a region of Denmark, a reading of the curriculum...... and a description of the organization of palliative care – there is a need for such inter-professional palliative care that raises the level of competences at the basic level and the sharing of knowledge as well as securing the continuous qualifying of healthcare staff working with palliative care....

  19. Rawlsian Justice and Palliative Care

    DEFF Research Database (Denmark)

    Knight, Carl; Albertsen, Andreas

    2015-01-01

    Palliative care serves both as an integrated part of treatment and as a last effort to care for those we cannot cure. The extent to which palliative care should be provided and our reasons for doing so have been curiously overlooked in the debate about distributive justice in health and healthcare...... to provide pain relief to those who need it as a supplement to treatment and, without justice-based reasons to provide palliative care to those whose opportunities cannot be restored. We conclude that this makes Daniels' framework much less attractive........ We argue that one prominent approach, the Rawlsian approach developed by Norman Daniels, is unable to provide such reasons and such care. This is because of a central feature in Daniels' account, namely that care should be provided to restore people's opportunities. Daniels' view is both unable...

  20. Standard of care in dentistry

    OpenAIRE

    Gokul Sridharan; Prithviraj Kallahalla Jagadish

    2012-01-01

    Medical ethics is primarily a field of applied ethics, the study of moral values and judgments as applicable to medicine. Dental practitioners constitute a group of health professionals who deal with human health care on a regular basis. Various ethical principles govern their conduct and their approach toward the patients. Ethical code of conduct prescribes a minimum standard of care which is applicable to all dental professionals. Substandard dental care is unacceptable and mounts to neglig...