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Sample records for cardiovascular nuclear medicine

  1. Instrumentation and organisation in cardiovascular nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear techniques, although generally accepted in medicine, require efficient instrumentation and close cooperation between the expert in nuclear medicine and the cardiologist. The methods most frequently applied are 201Tl scintiscanning, radionuclide angiocardiography and radionuclide ventriculography. Combined application of the latter two is particularly efficient. Tl scintiscanning is most frequently applied to determine myocardial vitality, the first-pass technique is used for morphological and the steady-state technique for functional examinations. Functional examinations of the coronary arteries are carried out directly by myocardial scintiscanning while radionuclide ventriculography yields information on the heamodynamic effect of stenosis of the coronary arteries via measurement of the ventricular function. In consequence, there is a wide range of indications in which myocardial scintiscanning and radionuclide ventriculography are equally applicable; myocardial scintiscanning has the advantage of simplicity while radionuclide ventriculography yields important supplementary information on the ventricular function. (orig.)

  2. Nuclear Medicine

    Science.gov (United States)

    ... Parents/Teachers Resource Links for Students Glossary Nuclear Medicine What is nuclear medicine? What are radioactive tracers? ... funded researchers advancing nuclear medicine? What is nuclear medicine? Nuclear medicine is a medical specialty that uses ...

  3. 'THE UNVEILED HEART' a teaching program in cardiovascular nuclear medicine

    International Nuclear Information System (INIS)

    The functional investigation of cardiac diseases using nuclear techniques involves several variables, such as myocardial perfusion, cellular viability or mechanical contraction. The combined, topographical and quantitative assessment of these variables can characterize the functional state of the heart in terms of normal myocardium, ischemia, hibernation or necrosis. The teaching program, 'The Unveiled Heart', has been designed in order to help nuclear physicians or cardiologists approaching these concepts and their implications for diagnosis of coronary artery disease, optimization of therapeutic strategies and prognosis evaluation. Anatomical correlations with coronary angiographic results obtained during balloon occlusion at the time of coronary angioplasty demonstrate the complementary role of imaging techniques and highlight the patient to patient variability of risk areas. A sectorial model derived from a polar projection of the myocardium presents for each sector the probability of involvement of a given coronary artery

  4. Radioiodination and Bio evaluation of Some Cardiovascular Drugs for Nuclear Medicine Application

    International Nuclear Information System (INIS)

    Nuclear medicine specialists use safe, painless, and cost-effective techniques to image the body and treat disease. Nuclear medicine imaging is unique, because it provides doctors with information about both structure and function. It is a way to gather medical information that would otherwise be unavailable, require surgery, or necessitate more expensive diagnostic tests. Today, nuclear medicine offers procedures that are essential in many medical specialties, from pediatrics to cardiology to psychiatry. Radiopharmacy is the science that deals largely with the preparation, compounding, Quality Control (QC), and dispensing of radiopharmaceuticals and radioisotopes for human use. Radio pharmacists are the personnel who perform these functions at large hospitals or medical centers. They are involved in manufacturing cold kits and in developing new agents and procedures. In this thesis it was studied the labeling of Deltiazem , Nefidipine and Valsartan with iodine -125 via an electrophilic substitution reaction. The biological distribution of these tracers were studied and was found the possibility of their use in cardiovascular disorders.

  5. Nuclear Medicine.

    Science.gov (United States)

    Badawi, Ramsey D.

    2001-01-01

    Describes the use of nuclear medicine techniques in diagnosis and therapy. Describes instrumentation in diagnostic nuclear medicine and predicts future trends in nuclear medicine imaging technology. (Author/MM)

  6. Nuclear medicine

    International Nuclear Information System (INIS)

    Several growth areas for nuclear medicine were defined. Among them were: cardiac nuclear medicine, neuro-psychiatric nuclear medicine, and cancer diagnosis through direct tumor imaging. A powerful new tool, Positron Emission Tomography (PET) was lauded as the impetus for new developments in nuclear medicine. The political environment (funding, degree of autonomy) was discussed, as were the economic and scientific environments

  7. Impact of nuclear medicine on the diagnosis and management of cardiovascular disease

    International Nuclear Information System (INIS)

    Recent advances in the methods of diagnostic cardiology have brought a change in emphasis toward noninvasive patient study. Nuclear Medicine techniques play an important part among noninvasive methods which enable diagnostic and therapeutic evaluation in the majority of patients with cardiac problems, without resorting to dangerous, painful and costly cardiac catheterization. Discussed are only a few of the myriad clinical applications which are rapidly making nuclear medicine techniques an integral part of the cardiologic diagnostic armamentarium

  8. Nuclear medicine

    International Nuclear Information System (INIS)

    The article deals with the growth of nuclear medicine in India. Radiopharmaceuticals both in elemental form and radiolabelled compounds became commercially available in India in 1961. Objectives and educational efforts of the Radiation Medicine Centre setup in Bombay are mentioned. In vivo tests of nuclear medicine such as imaging procedures, dynamic studies, dilution studies, thyroid function studies, renal function studies, linear function studies, blood flow, and absorption studies are reported. Techniques of radioimmunoassay are also mentioned. (S.K.K.)

  9. Nuclear medicine

    International Nuclear Information System (INIS)

    The task of the Expert Committee was to review the technical development and efficacy of nuclear medicine methods and to recommend the best possible means of establishing nuclear medicine services at various levels of medical care in different countries. After reviewing the contributions which nuclear medicine can make, the various types of medical institutions and hospitals in existence, the requirements, organization and funding of nuclear medicine services, and the cost/effectiveness of nuclear medicine, a number of recommendations were made. IAEA and WHO should make information on existing methods of cost/effectiveness analysis widely available; invite governments to include a description of such analysis methods in training programmes of their health officers; assist in the acquisition of the necessary data; and encourage and eventually support actual applications of such analyses to carefully selected nuclear medicine procedures in varying medicosocial environments. They were further recommended to study possible ways of improving reliability and ease of servicing nuclear medicine equipment, and extent of possible local construction; the possibility of making available supplies of matched characterized reagents for radioimmunoassay and related techniques; and to study the advantages of establishing a network of collaborating centres on an international basis

  10. Nuclear medicine

    International Nuclear Information System (INIS)

    Despite an aggressive, competitive diagnostic radiology department, the University Hospital, London, Ontario has seen a decline of 11% total (in vivo and in the laboratory) in the nuclear medicine workload between 1982 and 1985. The decline of in vivo work alone was 24%. This trend has already been noted in the U.S.. Nuclear medicine is no longer 'a large volume prosperous specialty of wide diagnostic application'

  11. General Nuclear Medicine

    Science.gov (United States)

    ... Resources Professions Site Index A-Z General Nuclear Medicine Nuclear medicine imaging uses small amounts of radioactive ... of General Nuclear Medicine? What is General Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  12. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  13. Children's (Pediatric) Nuclear Medicine

    Science.gov (United States)

    ... Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small amounts ... Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  14. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Resources Professions Site Index A-Z Children's (Pediatric) Nuclear Medicine Children’s (pediatric) nuclear medicine imaging uses small ... of Children's Nuclear Medicine? What is Children's (Pediatric) Nuclear Medicine? Nuclear medicine is a branch of medical ...

  15. Nuclear Medicine

    OpenAIRE

    Belzberg, Allan S.

    1986-01-01

    Nuclear medicine utilizes radioisotopes to diagnose and in some cases treat disease. Modern instruments can image their accumulation in an organ and provide quantitative data when indicated. The strength of these procedures is in the unique physiologic information they provide, rather than the presentation of precise anatomic detail.

  16. Nuclear medicine

    International Nuclear Information System (INIS)

    The document contains two articles dealing with the radioisotope scintigraphy of myocardium and gullet and forty-one abstracts of papers presented at the seminar ''Twenty-nine Days of Nuclear Medicine'' held in Olomovc, September 29 - October 1, 1992. The contributions, all within the INIS subject scope, are input to INIS. (Z.S.)

  17. Position paper of the Cardiovascular Committee of the European Association of Nuclear Medicine (EANM) on PET imaging of atherosclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Bucerius, Jan [Maastricht University Medical Center, Department of Nuclear Medicine, Maastricht (Netherlands); Maastricht University Medical Center, Cardiovascular Research Institute Maastricht (CARIM), Maastricht (Netherlands); University Hospital RWTH Aachen, RWTH Aachen, Department of Nuclear Medicine, Aachen (Germany); Maastricht University Medical Center (MUMC), Department of Nuclear Medicine and Cardiovascular Research Institute (CARIM), P. Debyelaan 25, HX, Maastricht (Netherlands); Hyafil, Fabien [Bichat University Hospital, Inserm 1148, DHU FIRE, Assistance Publique - Hopitaux de Paris, Department of Nuclear Medicine, Paris (France); Klinikum rechts der Isar, Technische Universitaet Muenchen, Department of Nuclear Medicine, Munich (Germany); Verberne, Hein J. [University of Amsterdam, Department of Nuclear Medicine, Academic Medical Center, Amsterdam (Netherlands); Slart, Riemer H.J.A. [University of Groningen, Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen (Netherlands); University of Twente, Department of Biomedical Photonic Imaging, Faculty of Science and Technology, Enschede (Netherlands); Lindner, Oliver [Heart and Diabetes Center NRW, Nuclear Medicine and Molecular Imaging, Institute of Radiology, Bad Oeynhausen (Germany); Sciagra, Roberto [University of Florence, Nuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences, Florence (Italy); Agostini, Denis [Normandie Universite, Department of Nuclear Medicine, CHU Cote de Nacre, Caen (France); Uebleis, Christopher [Ludwig-Maximilians Universitaet Muenchen, Department of Clinical Radiology, Muenchen (Germany); Gimelli, Alessia [Fondazione Toscana Gabriele Monasterio, Pisa (Italy); Hacker, Marcus [Medical University Vienna, Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided therapy, Vienna (Austria); Collaboration: on behalf of the Cardiovascular Committee of the European Association of Nuclear Medicine (EANM)

    2016-04-15

    Cardiovascular diseases are the leading cause of death not only in Europe but also in the rest of the World. Preventive measures, however, often fail and cardiovascular disease may manifest as an acute coronary syndrome, stroke or even sudden death after years of silent progression. Thus, there is a considerable need for innovative diagnostic and therapeutic approaches to improve the quality of care and limit the burden of cardiovascular diseases. During the past 10 years, several retrospective and prospective clinical studies have been published using {sup 18}F-fluorodeoxyglucose (FDG) positron emission tomography (PET) to quantify inflammation in atherosclerotic plaques. However, the current variety of imaging protocols used for vascular (arterial) imaging with FDG PET considerably limits the ability to compare results between studies and to build large multicentre imaging registries. Based on the existing literature and the experience of the Members of the European Association of Nuclear Medicine (EANM) Cardiovascular Committee, the objective of this position paper was to propose optimized and standardized protocols for imaging and interpretation of PET scans in atherosclerosis. These recommendations do not, however, replace the individual responsibility of healthcare professionals to make appropriate decisions in the circumstances of the individual study protocols used and the individual patient, in consultation with the patient and, where appropriate and necessary, the patient's guardian or carer. These recommendations suffer from the absence of conclusive evidence on many of the recommendations. Therefore, they are not intended and should not be used as ''strict guidelines'' but should, as already mentioned, provide a basis for standardized clinical atherosclerosis PET imaging protocols, which are subject to further and continuing evaluation and improvement. However, this EANM position paper might indeed be a first step towards &apos

  18. Position paper of the Cardiovascular Committee of the European Association of Nuclear Medicine (EANM) on PET imaging of atherosclerosis

    International Nuclear Information System (INIS)

    Cardiovascular diseases are the leading cause of death not only in Europe but also in the rest of the World. Preventive measures, however, often fail and cardiovascular disease may manifest as an acute coronary syndrome, stroke or even sudden death after years of silent progression. Thus, there is a considerable need for innovative diagnostic and therapeutic approaches to improve the quality of care and limit the burden of cardiovascular diseases. During the past 10 years, several retrospective and prospective clinical studies have been published using 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) to quantify inflammation in atherosclerotic plaques. However, the current variety of imaging protocols used for vascular (arterial) imaging with FDG PET considerably limits the ability to compare results between studies and to build large multicentre imaging registries. Based on the existing literature and the experience of the Members of the European Association of Nuclear Medicine (EANM) Cardiovascular Committee, the objective of this position paper was to propose optimized and standardized protocols for imaging and interpretation of PET scans in atherosclerosis. These recommendations do not, however, replace the individual responsibility of healthcare professionals to make appropriate decisions in the circumstances of the individual study protocols used and the individual patient, in consultation with the patient and, where appropriate and necessary, the patient's guardian or carer. These recommendations suffer from the absence of conclusive evidence on many of the recommendations. Therefore, they are not intended and should not be used as ''strict guidelines'' but should, as already mentioned, provide a basis for standardized clinical atherosclerosis PET imaging protocols, which are subject to further and continuing evaluation and improvement. However, this EANM position paper might indeed be a first step towards &apos

  19. Nuclear medicine

    International Nuclear Information System (INIS)

    Except for dedicated devices for mobile nuclear cardiology for instance, the market is set on variable angulation dual heads cameras. These cameras are suited for all general applications and their cost effectiveness is optimized. Now, all major companies have such a camera in their of products. But, the big question in nuclear medicine is about the future of coincidence imaging for the monitoring of treatments in oncology. Many companies are focused on WIP assessments to find out the right crustal thickness to perform both high energy FDG procedures and low energy Tc procedures, with the same SPECT camera. The classic thickness is 3/8''. Assessments are made with 1/2'', 5/8'' or 3/4'' crystals. If FDG procedures proved to be of great interest in oncology, it may lead to the design of a dedicated SPECT camera with a 1'' crustal. Due to the short half of FDG, it may be the dawning of slip ring technology. (e.g. Varicam from Elscint). The three small heads camera market seems to be depressed. Will the new three large heads camera unveiled by Picker, reverse that trend? The last important topic in nuclear medicine is the emergence of new flat digital detectors to get rid of the old bulky ones. Digirad is the first company to manufacture a commercial product based on that technology. Bichron, Siemens and General Electric are working on that development, too. But that technology is very expensive and the market for digital detection in nuclear medicine is not as large as the market in digital detection in radiology. (author)

  20. Nuclear medicine

    International Nuclear Information System (INIS)

    This article presents a brief history of nuclear medicine in France and describes the recent developments and equipment of the 3 techniques most used in hospital nuclear departments: 1) gamma-camera, 2) single photon emission computed tomography (SPECT), and 3) positron emission computed tomography (PECT). Concerning gamma-camera, a new design is being studied in a collaboration between the Saint-Gobain company and the LETI (a laboratory of Cea). In this innovative design the scintillator and the photomultiplier are replaced by a matrix of semi-conductor detectors based on CdZnTe crystal combined with an adequate electronic equipment. Concerning SPECT, many different techniques and equipment are used. Most improvements handle with the reduction of the survey time for the patient by using several detectors set on a ring around the patient. Concerning PECT, the developments follow 2 parallel ways: first the use of better scintillating materials for detecting 511 KeV photons (BGO: bismuth germanate, BaF2, LSO: lutetium orthosilicate, or GSO: gadolinium orthosilicate), and secondly the use of beta+ decay radionuclides that are more easily integrated in molecules similar to those present in the humane metabolism (18F through the fluorodeoxyglucose molecule). (A.C.)

  1. What Is Nuclear Medicine?

    Science.gov (United States)

    What is nuclear medicine? Nuclear medicine is a medical specialty that is used to diagnose and treat diseases in a safe and painless way. Nuclear medicine procedures permit the determination of medical information ...

  2. Robotic technology in cardiovascular medicine.

    Science.gov (United States)

    Bonatti, Johannes; Vetrovec, George; Riga, Celia; Wazni, Oussama; Stadler, Petr

    2014-05-01

    Robotic technology has been used in cardiovascular medicine since the late 1990s. Interventional cardiology, electrophysiology, endovascular surgery, minimally invasive cardiac surgery, and laparoscopic vascular surgery are all fields of application. Robotic devices enable endoscopic reconstructive surgery in narrow spaces and fast, very precise placement of catheters and devices in catheter-based interventions. In all robotic systems, the operator manipulates the robotic arms from a control station or console. In the field of cardiac surgery, mitral valve repair, CABG surgery, atrial septal defect repair, and myxoma resection can be achieved using robotic technology. Furthermore, vascular surgeons can perform a variety of robotically assisted operations to treat aortic, visceral, and peripheral artery disease. In electrophysiology, ablation procedures for atrial fibrillation can be carried out with robotic support. In the past few years, robotically assisted percutaneous coronary intervention and abdominal aortic endovascular surgery techniques have been developed. The basic feasibility and safety of robotic approaches in cardiovascular medicine has been demonstrated, but learning curves and the high costs associated with this technology have limited its widespread use. Nonetheless, increased procedural speed, accuracy, and reduced exposure to radiation and contrast agent in robotically assisted catheter-based interventions, as well as reduced surgical trauma and shortened patient recovery times after robotic cardiovascular surgery are promising achievements in the field. PMID:24663088

  3. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... referring physician. top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations is ... risk is very low compared with the potential benefits. Nuclear medicine diagnostic procedures have been used for ...

  4. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... Tell your doctor about your child’s recent illnesses, medical conditions, medications and allergies. Depending on the type ... Nuclear Medicine? Nuclear medicine is a branch of medical imaging that uses small amounts of radioactive material ...

  5. Nuclear energy and medicine

    International Nuclear Information System (INIS)

    The applications of nuclear energy on medicine, as well as the basic principles of these applications, are presented. The radiological diagnosis, the radiotherapy, the nuclear medicine, the radiological protection and the production of radioisotopes are studied. (M.A.C.)

  6. A moving image system for cardiovascular nuclear medicine. A dedicated auxiliary device for the total capacity imaging system for multiple plane dynamic colour display

    International Nuclear Information System (INIS)

    The recent device of the authors, the dedicated multiplane dynamic colour image display system for nuclear medicine, is discussed. This new device is a hardware-based auxiliary moving image system (AMIS) attached to the total capacity image processing system of the authors' department. The major purpose of this study is to develop the dedicated device so that cardiovascular nuclear medicine and other dynamic studies will include the ability to assess the real time delicate processing of the colour selection, edge detection, phased analysis, etc. The auxiliary system consists of the interface for image transferring, four IC refresh memories of 64x64 matrix with 10 bit count depth, a digital 20-in colour TV monitor, a control keyboard and a control panel with potentiometers. This system has five major functions for colour display: (1) A microcomputer board can select any one of 40 different colour tables preset in the colour transformation RAM. This key also provides edge detection at a certain level of the count by leaving the optional colour and setting the rest of the levels at 0 (black); (2) The arithmetic processing circuit performs the operation of the fundamental rules, permitting arithmetic processes of the two images; (3) The colour level control circuit is operated independently by four potentiometers for four refresh image memories, so that the gain and offset of the colour level can be manually and visually controlled to the satisfaction of the operator; (4) The simultaneous CRT display of the maximum four images with or without cinematic motion is possible; (5) The real time movie interval is also adjustable by hardware, and certain frames can be freezed with overlapping of the dynamic frames. Since this system of AMIS is linked with the whole capacity image processing system of the CPU size of 128kW, etc., clinical applications are not limited to cardiovascular nuclear medicine. (author)

  7. Cardiovascular Disease, Mitochondria, and Traditional Chinese Medicine

    OpenAIRE

    Jie Wang; Fei Lin; Li-li Guo; Xing-jiang Xiong; Xun Fan

    2015-01-01

    Recent studies demonstrated that mitochondria play an important role in the cardiovascular system and mutations of mitochondrial DNA affect coronary artery disease, resulting in hypertension, atherosclerosis, and cardiomyopathy. Traditional Chinese medicine (TCM) has been used for thousands of years to treat cardiovascular disease, but it is not yet clear how TCM affects mitochondrial function. By reviewing the interactions between the cardiovascular system, mitochondrial DNA, and TCM, we sho...

  8. Fundamentals of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Alazraki, N.P.; Mishkin, F.S.

    1984-01-01

    This guidebook for clinical nuclear medicine is written as a description of how nuclear medicine procedures should be used by clinicians in evaluating their patients. It is designed to assist medical students and physicians in becoming acquainted with nuclear medicine techniques for detecting and evaluating most common disorders. The material provides an introduction to, not a textbook of, nuclear medicine. Each chapter is devoted to a particular organ system or topic relevant to the risks and benefits involved in nuclear medicine studies. The emphasis is on presenting the rationales for ordering the various clinical imaging procedures performed in most nuclear medicine departments. Where appropriate, alternative imaging modalities including ultrasound, computed tomography imaging, and radiographic special procedures are discussed. Comparative data between nuclear medicine imaging and other modalities are presented to help guide the practicing clinician in the selection of the most appropriate procedure for a given problem.

  9. Nuclear medicine physics

    CERN Document Server

    De Lima, Joao Jose

    2011-01-01

    Edited by a renowned international expert in the field, Nuclear Medicine Physics offers an up-to-date, state-of-the-art account of the physics behind the theoretical foundation and applications of nuclear medicine. It covers important physical aspects of the methods and instruments involved in modern nuclear medicine, along with related biological topics. The book first discusses the physics of and machines for producing radioisotopes suitable for use in conventional nuclear medicine and PET. After focusing on positron physics and the applications of positrons in medicine and biology, it descr

  10. Clinical nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine appears to be increasingly expanding both in its scope and its direct practical clinical usefullness. In view of the manifold possibilities offered by nuclear medicine this review has intentionally been very rapid and, if one will pardon the pun, a scunning approach to nuclear medicine applications. Only selected highlights in the expanding field of nuclear medicine were discussed. In the past 25 years nuclear medicine has emerged as an integrated medical discipline. It now plays a major role in patient management and has significantly expanded the physicians' diagnostic tools. As illustrated here, radionuclide procedures are currently applied in almost every medical speciality. In any event, the tests that comprise nuclear medicine have succeeded because they are rapid, effective, safe and insexpensive, and can be performed without discomfort for the patient. (orig.)

  11. Tele-nuclear medicine

    OpenAIRE

    Nathanael Sabbah; Sinclair Wynchank

    2014-01-01

    This article presents a description of tele-nuclear medicine and, after outlining its history, a wide, representative range of its applications. Tele-nuclear medicine has benefited greatly from technological progress, which for several decades has provided greater data transfer rates and storage capacity at steadily decreasing cost. Differences in the practice of nuclear medicine between developed and developing countries arise mainly from disparities in their available infrastructure, fundin...

  12. Fundamentals of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Alazraki, N.P.; Mishkin, F.S.

    1988-01-01

    The book begins with basic science and statistics relevant to nuclear medicine, and specific organ systems are addressed in separate chapters. A section of the text also covers imaging of groups of disease processes (eg, trauma, cancer). The authors present a comparison between nuclear medicine techniques and other diagnostic imaging studies. A table is given which comments on sensitivities and specificities of common nuclear medicine studies. The sensitivities and specificities are categorized as very high, high, moderate, and so forth.

  13. Fundamentals of nuclear medicine

    International Nuclear Information System (INIS)

    The book begins with basic science and statistics relevant to nuclear medicine, and specific organ systems are addressed in separate chapters. A section of the text also covers imaging of groups of disease processes (eg, trauma, cancer). The authors present a comparison between nuclear medicine techniques and other diagnostic imaging studies. A table is given which comments on sensitivities and specificities of common nuclear medicine studies. The sensitivities and specificities are categorized as very high, high, moderate, and so forth

  14. Personalized Medicine in Cardiovascular Diseases

    OpenAIRE

    Lee, Moo-Sik; Flammer, Andreas J.; Lerman, Lilach O.; Lerman, Amir

    2012-01-01

    Personalized medicine is a novel medical model with all decisions and practices being tailored to individual patients in whatever ways possible. In the era of genomics, personalized medicine combines the genetic information for additional benefit in preventive and therapeutic strategies. Personalized medicine may allow the physician to provide a better therapy for patients in terms of efficiency, safety and treatment length to reduce the associated costs. There was a remarkable growth in scie...

  15. Technologists for Nuclear Medicine

    Science.gov (United States)

    Barnett, Huey D.

    1974-01-01

    Physicians need support personnel for work with radioisotopes in diagnosing dangerous diseases. The Nuclear Medicine Technology (NMT) Program at Hillsborough Community College in Tampa, Florida, is described. (MW)

  16. Lymphatic System in Cardiovascular Medicine.

    Science.gov (United States)

    Aspelund, Aleksanteri; Robciuc, Marius R; Karaman, Sinem; Makinen, Taija; Alitalo, Kari

    2016-02-01

    The mammalian circulatory system comprises both the cardiovascular system and the lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a unidirectional transit pathway from the extracellular space to the venous system. It actively regulates tissue fluid homeostasis, absorption of gastrointestinal lipids, and trafficking of antigen-presenting cells and lymphocytes to lymphoid organs and on to the systemic circulation. The cardinal manifestation of lymphatic malfunction is lymphedema. Recent research has implicated the lymphatic system in the pathogenesis of cardiovascular diseases including obesity and metabolic disease, dyslipidemia, inflammation, atherosclerosis, hypertension, and myocardial infarction. Here, we review the most recent advances in the field of lymphatic vascular biology, with a focus on cardiovascular disease. PMID:26846644

  17. PACS in nuclear medicine

    International Nuclear Information System (INIS)

    PACS (Picture Archiving and Communication System) is being rapidly spread and installed in many hospitals, but most of the system do not include nuclear medicine field. Although additional costs of hardware for nuclear medicine PACS is low, the complexity in developing viewing software and little market have made the nuclear medicine PACS not popular. Most PACS utilize DICOM 3.0 as standard format, but standard format in nuclear medicine has been Interfile. Interfile should be converted into DICOM format if nuclear images are to be stored and visualized in most PACS. Nowadays, many vendors supply the DICOM option in gamma camera and PET. Several hospitals in Korea have already installed nucler PACS with DICOM, but only the screen captured images are supplied. Software for visualizing pseudo-color with color lookup tables and expressing with volume view should be developed to fulfill the demand of referring physicians and nuclear medicine physicians. PACS is going to integrate not only radiologic images but also endoscopic and pathologic images. Web and PC based PACS is now a trend and is much compatible with nuclear medicine PACS. Most important barrier for nuclear medicine PACS that we encounter is not a technical problem, but indifference of investor such as administrator of hospital or PACS. Now it is time to support and invest for the development of nuclear medicine PACS

  18. Precision Medicine, Cardiovascular Disease and Hunting Elephants.

    Science.gov (United States)

    Joyner, Michael J

    2016-01-01

    Precision medicine postulates improved prediction, prevention, diagnosis and treatment of disease based on patient specific factors especially DNA sequence (i.e., gene) variants. Ideas related to precision medicine stem from the much anticipated "genetic revolution in medicine" arising seamlessly from the human genome project (HGP). In this essay I deconstruct the concept of precision medicine and raise questions about the validity of the paradigm in general and its application to cardiovascular disease. Thus far precision medicine has underperformed based on the vision promulgated by enthusiasts. While niche successes for precision medicine are likely, the promises of broad based transformation should be viewed with skepticism. Open discussion and debate related to precision medicine are urgently needed to avoid misapplication of resources, hype, iatrogenic interventions, and distraction from established approaches with ongoing utility. Failure to engage in such debate will lead to negative unintended consequences from a revolution that might never come. PMID:26902518

  19. Cardiovascular Disease, Mitochondria, and Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Jie Wang

    2015-01-01

    Full Text Available Recent studies demonstrated that mitochondria play an important role in the cardiovascular system and mutations of mitochondrial DNA affect coronary artery disease, resulting in hypertension, atherosclerosis, and cardiomyopathy. Traditional Chinese medicine (TCM has been used for thousands of years to treat cardiovascular disease, but it is not yet clear how TCM affects mitochondrial function. By reviewing the interactions between the cardiovascular system, mitochondrial DNA, and TCM, we show that cardiovascular disease is negatively affected by mutations in mitochondrial DNA and that TCM can be used to treat cardiovascular disease by regulating the structure and function of mitochondria via increases in mitochondrial electron transport and oxidative phosphorylation, modulation of mitochondrial-mediated apoptosis, and decreases in mitochondrial ROS. However further research is still required to identify the mechanism by which TCM affects CVD and modifies mitochondrial DNA.

  20. Clinical nuclear medicine

    International Nuclear Information System (INIS)

    The importance of nuclear methods within today's medicine derives decisively from the field of diagnostics. Among the clinical treatment possibilities on the whole, therapy with unsealed radioactive sources is for the time being restricted to few diseases. The use of radioactive labeling in biology, biochemistry and, especially, pharmacology and the rest of fundamental medical research does not belong to the actual specialty of nuclear medicine. Nuclear in-vitro diagnostics, which currently account for about two thirds of all activities in nuclear medicine, are largely excluded from this survey, which is mainly restricted to nuclear diagnostics in vivo. This presentation of nuclear diagnostics in vivo is addressed above all to non-specialists who are to be made familiar with the modern methods of clinical nuclear medicine so that these investigation methods could be more effectively used in future both with qualitative and quantitative regards. (orig./MG)

  1. Nuclear medicine: the Philippine Heart Center experience

    International Nuclear Information System (INIS)

    The following is a report of a three (3) months on-the-job training in Nuclear Medicine at the Nuclear Medicine Department of the Philippine Heart Center. The hospital has current generation nuclear medicine instruments with data processor and is capable of a full range of in vivo and in vitro procedures. Gamma camera is the principal instrument for imaging in nuclear medicine used in the Philippine Heart Center. Thyroid scanning procedure is being performed with these instruments. Also the cardiovascular procedures, the pulmonary, skeletal, renal and hepatobiliary procedures were being performed with the use of gamma camera. Special emphasis is on nuclear cardiology since the PHC attends primarily to cardiovascular patients. (auth.)

  2. Your Radiologist Explains Nuclear Medicine

    Science.gov (United States)

    ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease in its ... abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – ...

  3. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease ...

  4. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... produced by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org ... I’d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify ...

  5. Veterinary nuclear medicine

    International Nuclear Information System (INIS)

    A brief review is presented of the expanding horizons of nuclear medicine, the equipment necessary for a nuclear medicine laboratory is listed, and the value of this relatively new field to the veterinary clinician is indicated. Although clinical applications to veterinary medicine have not kept pace with those of human medicine, many advances have been made, particularly in the use of in vitro techniques. Areas for expanded applications should include competitive protein binding and other in vitro procedures, particularly in connection with metabolic profile studies. Indicated also is more intensive application by the veterinarian of imaging procedures, which have been found to be of such great value to the physician. (U.S.)

  6. Practical nuclear medicine

    CERN Document Server

    Gemmell, Howard G; Sharp, Peter F

    2006-01-01

    Nuclear medicine plays a crucial role in patient care, and this book is an essential guide for all practitioners to the many techniques that inform clinical management. The first part covers the scientific basis of nuclear medicine, the rest of the book deals with clinical applications. Diagnostic imaging has an increasingly important role in patient management and, despite advances in other modalities (functional MRI and spiral CT), nuclear medicine continues to make its unique contribution by its ability to demonstrate physiological function. This book is also expanded by covering areas of d

  7. Radionuclides in diagnostic nuclear medicine

    International Nuclear Information System (INIS)

    Diagnostic Nuclear Medicine (NM) is an essential procedure in modern medical practice. Recent survey reported that more than 2 million NM examinations are conducted every year in Japan. Around 75% of diagnostic NM employs single photon emission tomography (SPECT) with 99mTc, 123I, 133Xe, or 201Tl-labeled compound, and 25% positron emission tomography (PET) with 18F-fluorodeoxy glucose, 15O-labeled H2O, CO, O2, or 11C-labeled compounds. Modern medicine is based on the intervention of molecular pathology of the diseases. Therefore, NM is expanding in number and in quality in daily medical practice including early diagnosis of Alzheimer’s diseases, cancer, and cardiovascular diseases, strategy decision of treatment, evaluation of regeneration medicine. Furthermore, the NM is being utilized to facilitate new drug development. Combining molecular diagnosis with radionuclide therapy (Theranostics) is another future direction of clinical NM. (author)

  8. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... variety of diseases, including many types of cancers, heart disease, gastrointestinal, endocrine, neurological disorders and other abnormalities ... and bladder. bones. liver and gallbladder. gastrointestinal tract. heart. lungs. brain. thyroid. Nuclear medicine scans are typically ...

  9. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... after leaving the nuclear medicine facility. Through the natural process of radioactive decay, the small amount of radiotracer in your child’s body will lose its radioactivity over time. In many cases, the radioactivity will ...

  10. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... nuclear medicine imaging uses small amounts of radioactive materials called radiotracers, a special camera and a computer ... medical imaging that uses small amounts of radioactive material to diagnose and determine the severity of or ...

  11. Children's (Pediatric) Nuclear Medicine

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    Full Text Available ... Videos related to Children's (Pediatric) Nuclear Medicine About this Site RadiologyInfo.org is produced by: Please note ... you can search the ACR-accredited facilities database . This website does not provide cost information. The costs ...

  12. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... not experience any discomfort. When swallowed, the radiotracer has little or no taste. If inhaled, your child ... after the nuclear medicine scan. If the child has been sedated, you will receive specific instructions to ...

  13. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations ... diagnosis or to determine appropriate treatment, if any. Risks Because the doses of radiotracer administered are small, ...

  14. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... referring physician. top of page What are the benefits vs. risks? Benefits The information provided by nuclear medicine examinations is ... the possible charges you will incur. Web page review process: This Web page is reviewed regularly by ...

  15. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... after the procedure? Except for intravenous injections, most nuclear medicine procedures are painless and are rarely associated with significant discomfort or side effects. If the radiotracer is given intravenously, your child ...

  16. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... leaving the nuclear medicine facility. Through the natural process of radioactive decay, the small amount of radiotracer ... possible charges you will incur. Web page review process: This Web page is reviewed regularly by a ...

  17. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce ... manufacturers are now making single photon emission computed tomography/computed tomography (SPECT/CT) and positron emission tomography/ ...

  18. Nuclear tele medicine; Telemedicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Vargas, L.; Hernandez, F.; Fernandez, R. [Departamento de Medicina Nuclear, Imagenologia Diagnostica, Xalapa, Veracruz (Mexico)

    2005-07-01

    The great majority of the digital images of nuclear medicine are susceptible of being sent through internet. This has allowed that the work in diagnosis cabinets by image it can benefit of this modern technology. We have presented in previous congresses works related with tele medicine, however, due to the speed in the evolution of the computer programs and the internet, becomes necessary to make a current position in this modality of work. (Author)

  19. Clinical use of quantitative cardiac perfusion PET: rationale, modalities and possible indications. Position paper of the Cardiovascular Committee of the European Association of Nuclear Medicine (EANM).

    Science.gov (United States)

    Sciagrà, Roberto; Passeri, Alessandro; Bucerius, Jan; Verberne, Hein J; Slart, Riemer H J A; Lindner, Oliver; Gimelli, Alessia; Hyafil, Fabien; Agostini, Denis; Übleis, Christopher; Hacker, Marcus

    2016-07-01

    Until recently, PET was regarded as a luxurious way of performing myocardial perfusion scintigraphy, with excellent image quality and diagnostic capabilities that hardly justified the additional cost and procedural effort. Quantitative perfusion PET was considered a major improvement over standard qualitative imaging, because it allows the measurement of parameters not otherwise available, but for many years its use was confined to academic and research settings. In recent years, however, several factors have contributed to the renewal of interest in quantitative perfusion PET, which has become a much more readily accessible technique due to progress in hardware and the availability of dedicated and user-friendly platforms and programs. In spite of this evolution and of the growing evidence that quantitative perfusion PET can play a role in the clinical setting, there are not yet clear indications for its clinical use. Therefore, the Cardiovascular Committee of the European Association of Nuclear Medicine, starting from the experience of its members, decided to examine the current literature on quantitative perfusion PET to (1) evaluate the rationale for its clinical use, (2) identify the main methodological requirements, (3) identify the remaining technical difficulties, (4) define the most reliable interpretation criteria, and finally (5) tentatively delineate currently acceptable and possibly appropriate clinical indications. The present position paper must be considered as a starting point aiming to promote a wider use of quantitative perfusion PET and to encourage the conception and execution of the studies needed to definitely establish its role in clinical practice. PMID:26846913

  20. Nuclear medicine resources manual

    International Nuclear Information System (INIS)

    Over the past decade many IAEA programmes have significantly enhanced the capabilities of numerous Member States in the field of nuclear medicine. Functional imaging using nuclear medicine procedures has become an indispensable tool for the diagnosis, treatment planning and management of patients. However, due to the heterogeneous growth and development of nuclear medicine in the IAEA's Member States, the operating standards of practice vary considerably from country to country and region to region. This publication is the result of the work of over 30 international professionals who have assisted the IAEA in the process of standardization and harmonization. This manual sets out the prerequisites for the establishment of a nuclear medicine service, including basic infrastructure, suitable premises, reliable supply of electricity, maintenance of a steady temperature, dust exclusion for gamma cameras and radiopharmacy dispensaries. It offers clear guidance on human resources and training needs for medical doctors, technologists, radiopharmaceutical scientists, physicists and specialist nurses in the practice of nuclear medicine. The manual describes the requirements for safe preparation and quality control of radiopharmaceuticals. In addition, it contains essential requirements for maintenance of facilities and instruments, for radiation hygiene and for optimization of nuclear medicine operational performance with the use of working clinical protocols. The result is a comprehensive guide at an international level that contains practical suggestions based on the experience of professionals around the globe. This publication will be of interest to nuclear medicine physicians, radiologists, medical educationalists, diagnostic centre managers, medical physicists, medical technologists, radiopharmacists, specialist nurses, clinical scientists and those engaged in quality assurance and control systems in public health in both developed and developing countries

  1. The Middle Ages Contributions to Cardiovascular Medicine.

    Science.gov (United States)

    Ranhel, André Silva; Mesquita, Evandro Tinoco

    2016-04-01

    The historical period called the Middle Ages, a long interval between the 5th and the 15th centuries, is still commonly known as the Dark Ages, especially in the area of health sciences. In the last decades, this "classic" view of the Middle Ages has been gradually modified with advances in historiographical studies and the history of science. During that period in Western Europe, knowledge about the human body suffered a regression in terms of anatomy and physiology, with the predominance of religious conceptions mainly about diseases and their treatments. Knowledge on the cardiovascular system and heart diseases has been classically described as a repetition of the concepts developed by Galen from the dissection of animals and his keen sense of observation. However, the Middle East, especially Persia, was the birth place of a lot of intellectuals who preserved the ancient knowledge of the Greeks while building new knowledge and practices, especially from the 8th to the 13th century. The invasion of the Arabs in North of Africa and the Iberian Peninsula and the eclosion of the Crusades resulted in a greater contact between the East and the West, which in turn brought on the arrival of the Arab medical knowledge, among others, to 12th century Europe. Such fact contributed to an extremely important change in the scientific medical knowledge in the West, leading to the incorporation of different concepts and practices in the field of cardiovascular Medicine. The new way of teaching and practicing Medicine of the great Arab doctors, together with the teaching hospitals and foundations in the Koran, transformed the Medicine practiced in Europe definitely. The objective of this paper is to describe the knowledge drawn up from the Middle Ages about the cardiovascular system, its understanding and therapeutic approach to cardiologists and cardiovascular surgeons. PMID:27556317

  2. Nuclear tele medicine

    International Nuclear Information System (INIS)

    The great majority of the digital images of nuclear medicine are susceptible of being sent through internet. This has allowed that the work in diagnosis cabinets by image it can benefit of this modern technology. We have presented in previous congresses works related with tele medicine, however, due to the speed in the evolution of the computer programs and the internet, becomes necessary to make a current position in this modality of work. (Author)

  3. Pediatric nuclear medicine

    International Nuclear Information System (INIS)

    This symposium presented the latest techniques and approaches to the proper medical application of radionuclides in pediatrics. An expert faculty, comprised of specialists in the field of pediatric nuclear medicine, discussed the major indications as well as the advantages and potential hazards of nuclear medicine procedures compared to other diagnostic modalities. In recent years, newer radiopharmaceuticals labeled with technetium-99m and other short-lived radionuclides with relatively favorable radiation characteristics have permitted a variety of diagnostic studies that are very useful clinically and carry a substantially lower radiation burden then many comparable X-ray studies. This new battery of nuclear medicine procedures is now widely available for diagnosis and management of pediatric patients. Many recent research studies in children have yielded data concerning the effacacy of these procedures, and current recommendations will be presented by those involved in conducting such studies. Individual papers are processed separately for the Energy Data Base

  4. Nuclear medicine tomorrow

    International Nuclear Information System (INIS)

    The purpose of this Workshop was to discuss and promote future nuclear medicine applications. Atomic Energy of Canada Limited (AECL) is determined to assist in this role. A major aim of this gathering was to form an interface that was meaningful, representative of the two entities, and above all, on-going. In the opening address, given by Mr. J. Donnelly, President of AECL, this strong commitment was emphasized. In the individual sessions, AECL participants outlined R and D programs and unique expertise that promised to be of interest to members of the nuclear medicine community. The latter group, in turn, described what they saw as some problems and needs of nuclear medicine, especially in the near future. These Proceedings comprise the record of the formal presentations. Additionally, a system of reporting by rapporteurs insured a summary of informal discussions at the sessions and brought to focus pertinent conclusions of the workshop attendees

  5. Pediatric nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    This symposium presented the latest techniques and approaches to the proper medical application of radionuclides in pediatrics. An expert faculty, comprised of specialists in the field of pediatric nuclear medicine, discussed the major indications as well as the advantages and potential hazards of nuclear medicine procedures compared to other diagnostic modalities. In recent years, newer radiopharmaceuticals labeled with technetium-99m and other short-lived radionuclides with relatively favorable radiation characteristics have permitted a variety of diagnostic studies that are very useful clinically and carry a substantially lower radiation burden then many comparable X-ray studies. This new battery of nuclear medicine procedures is now widely available for diagnosis and management of pediatric patients. Many recent research studies in children have yielded data concerning the effacacy of these procedures, and current recommendations will be presented by those involved in conducting such studies. Individual papers are processed separately for the Energy Data Base.

  6. Physics in nuclear medicine

    CERN Document Server

    Cherry, Simon R; Phelps, Michael E

    2012-01-01

    Physics in Nuclear Medicine - by Drs. Simon R. Cherry, James A. Sorenson, and Michael E. Phelps - provides current, comprehensive guidance on the physics underlying modern nuclear medicine and imaging using radioactively labeled tracers. This revised and updated fourth edition features a new full-color layout, as well as the latest information on instrumentation and technology. Stay current on crucial developments in hybrid imaging (PET/CT and SPECT/CT), and small animal imaging, and benefit from the new section on tracer kinetic modeling in neuroreceptor imaging.

  7. Nuclear medicine in China

    International Nuclear Information System (INIS)

    Since China first applied isotopes to medical research in 1956, over 800 hospitals and research institutions with 4000 staff have taken up nuclear technology. So far, over 120 important biologically active materials have been measured by radioimmunoassay in China, and 44 types of RIA kit have been supplied commercially. More than 50,000 cases of hyperthyroidism have been treated satisfactorily with 131I. Radionuclide imaging of practically all organs and systems of the human body has been performed, and adrenal imaging and nuclear cardiology have become routine clinical practice in several large hospitals. The thyroid iodine uptake test, renogram tracing and cardiac function studies with a cardiac probe are also commonly used in most Chinese hospitals. The active principles of more than 60 medicinal herbs have been labelled with isotopes in order to study the drug metabolism and mechanism of action. Through the use of labelled neurotransmitters or deoxyglucose, RIA, radioreceptor assay and autoradiography, Chinese researchers have made remarkable achievements in the study of the scientific basis of acupuncture analgesia. In 1980 the Chinese Society of Nuclear Medicine was founded, and since 1981 the Chinese Journal of Nuclear Medicine has been published. Although nuclear medicine in China has already made some progress, when compared with advanced countries, much progress is still to be made. It is hoped that international scientific exchange will be strengthened in the future. (author)

  8. Computational fluid dynamics modelling in cardiovascular medicine.

    Science.gov (United States)

    Morris, Paul D; Narracott, Andrew; von Tengg-Kobligk, Hendrik; Silva Soto, Daniel Alejandro; Hsiao, Sarah; Lungu, Angela; Evans, Paul; Bressloff, Neil W; Lawford, Patricia V; Hose, D Rodney; Gunn, Julian P

    2016-01-01

    This paper reviews the methods, benefits and challenges associated with the adoption and translation of computational fluid dynamics (CFD) modelling within cardiovascular medicine. CFD, a specialist area of mathematics and a branch of fluid mechanics, is used routinely in a diverse range of safety-critical engineering systems, which increasingly is being applied to the cardiovascular system. By facilitating rapid, economical, low-risk prototyping, CFD modelling has already revolutionised research and development of devices such as stents, valve prostheses, and ventricular assist devices. Combined with cardiovascular imaging, CFD simulation enables detailed characterisation of complex physiological pressure and flow fields and the computation of metrics which cannot be directly measured, for example, wall shear stress. CFD models are now being translated into clinical tools for physicians to use across the spectrum of coronary, valvular, congenital, myocardial and peripheral vascular diseases. CFD modelling is apposite for minimally-invasive patient assessment. Patient-specific (incorporating data unique to the individual) and multi-scale (combining models of different length- and time-scales) modelling enables individualised risk prediction and virtual treatment planning. This represents a significant departure from traditional dependence upon registry-based, population-averaged data. Model integration is progressively moving towards 'digital patient' or 'virtual physiological human' representations. When combined with population-scale numerical models, these models have the potential to reduce the cost, time and risk associated with clinical trials. The adoption of CFD modelling signals a new era in cardiovascular medicine. While potentially highly beneficial, a number of academic and commercial groups are addressing the associated methodological, regulatory, education- and service-related challenges. PMID:26512019

  9. Nuclear imaging of cardiovascular disease

    International Nuclear Information System (INIS)

    Nuclear imaging methods provide noninvasive indexes of myocardial function, perfusion, and metabolism and are well accepted in clinical cardiology. Advances in prevention and treatment of cardiac disease have resulted in decreasing cardiovascular mortality in industrialized nations. The improvement in therapeutic options has increased the demand for diagnostic tests that might guide clinical decision making. Information beyond the pure anatomic characterization of coronary stenoses is required. Nuclear imaging can be used for early detection and monitoring of the severity and extent of disease. The prognostic potential of such functional testing is being increasingly appreciated and used to guide therapy, thereby resulting in improvement of the quality and cost-effectiveness of the workup of patients with cardiovascular disease. Extensive clinical validation has resulted in growing acceptance of these techniques. Furthermore, ongoing improvement of imaging techniques and development of new radiopharmaceuticals will pave the way for disease-specific, molecular-targeted cardiac imaging in the future. (orig.)

  10. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... like? Special camera or imaging devices used in nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). The gamma camera, , also called a scintillation camera, detects radioactive energy that is emitted from the patient's body and ...

  11. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... diagnoses. In addition, manufacturers are now making single photon emission computed tomography/computed tomography (SPECT/CT) and ... nuclear medicine include the gamma camera and single-photon emission-computed tomography (SPECT). The gamma camera, , also ...

  12. Nuclear Medicine in India

    Directory of Open Access Journals (Sweden)

    R.D. Lele

    1990-10-01

    Full Text Available The regular supply of radiopharmaceuticals and radioimmunoassay kits from BARC has been an important factor in the development of nuclear medicine in India. However, a major stumbling block has been the non-availability of suitable instrumentation systems (especially the computer-assisted gamma camera at an affordable price. Two recent developments, viz., the creation of the Board of Radioisotope Technology by the Department of Atomic Energy, and the efforts of Electronic Corporation of India Ltd. to design indigenously a gamma camera with a computer attachment, hold promise for the future healthy and rapid growth of nuclear medicine in the country. Training in nuclear medicine at the post-graduate level is gradually picking up. Nuclear medicine is essentially applied physiology and biochemistry, and provides an orientation, different from those of the anatomist and physiologist. The gamma camera, SPECT and PET enable the study of dynamic metabolic function resolution to spatial and temporal resolutions. Newer developments in tagged monoclonal antibodies hold promise for a better understanding of infectious and inflammatory disease which are a burden in the developing countries.

  13. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... pictures and provides molecular information. In many centers, nuclear medicine images can be superimposed with computed tomography (CT) or magnetic resonance imaging (MRI) to produce special views, a practice known as image fusion or co-registration. These views allow the information ...

  14. Nuclear techniques in medicine

    International Nuclear Information System (INIS)

    Nuclear physics has played a large role in medical treatment and diagnosis, from the technologies used in nuclear physics experiments to nuclear reactions. Particle detector technology from experimental nuclear and particle physics is the basis of the various tomographic imaging modalities such as: the radioactive tracers used in nuclear medicine result from neutron induced reactions using nuclear reactor facilities; cyclotron production of short-lived isotopes which allows metabolism of brain and cardiac tissue to be measured; in-vivo neutron activation analysis which allows the measurement of trace elements in the body. The purpose of this presentation is to illustrate some of those techniques such as, particle-beam treatments, neutron activation analyses, magnetic resonance imaging, and the physics involved. 5 figs., 1 tab., ills

  15. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Uterine Fibroids Dementia Video: General Ultrasound Video: Pediatric Nuclear Medicine Radiology and You About this Site RadiologyInfo. ... produced by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org ...

  16. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Fibroids Dementia Video: General Ultrasound Video: Pediatric Nuclear Medicine Radiology and You About this Site RadiologyInfo.org ... by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! ...

  17. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... this Site RadiologyInfo.org is produced by: Image/Video Gallery Your Radiologist Explains Nuclear Medicine Transcript Welcome ... Recently posted: Focused Ultrasound for Uterine Fibroids Dementia Video: General Ultrasound Video: Pediatric Nuclear Medicine Radiology and ...

  18. Nuclear medicine technology study guide

    CERN Document Server

    Patel, Dee

    2011-01-01

    Nuclear Medicine Technology Study Guide presents a comprehensive review of nuclear medicine principles and concepts necessary for technologists to pass board examinations. The practice questions and content follow the guidelines of the Nuclear Medicine Technology Certification Board (NMTCB) and American Registry of Radiological Technologists (ARRT), allowing test takers to maximize their success in passing the examinations. The book is organized by sections of increasing difficulty, with over 600 multiple-choice questions covering all areas of nuclear medicine, including radiation safety; radi

  19. Nuclear medicine in sports

    International Nuclear Information System (INIS)

    Nuclear medicine can synergistically contribute to the sports medicine field, in the management of sports-related stress injures. Bone scintigraphy is commonly requested for evaluation of athletes with pain. Three-Phase 99mTc MDP Bone Scan has emerged as the imaging reference standard for diagnosing such injuries. The inherently high-contrast resolution of the bone scan allows early detection of bone trauma and becomes positive within six to seventy-two hours after the onset of symptoms. The bone scan is able to demonstrate stress injuries days to weeks before the radiograph

  20. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... d like to talk to you about nuclear medicine. Nuclear medicine offers the potential to identify disease in its ... abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – ...

  1. Mongolia and nuclear medicine development

    International Nuclear Information System (INIS)

    Full text: Mongolia is a large, landlocked and sparsely populated country in the northern part of Central Asia, located between Russia on the north and China on east, south and west. Its total land area of 1.5 millions square kilometers is about the size if India or large than Alaska, but contains only 2.3 million population or 1.3 person per square kilometer. It is 2400 kilometers long from east to west maximum of 1260 kilometers from north to south.The priority problems in health.Democratic political reforms since 1990 saw a major transformation process, which is aimed at changing the centrally planned economy to one based on market orient principles. Mongolia is in a gradual epidemiological transition from preponderance of infectious diseases towards non-communicable and degenerative diseases. Mean features of this transition are sharp decrease in mortality from infectious and parasitic diseases and sharp increase in mortality from diseases of the circulatory system and neoplasms. Life expectancy at birth was 65.7 year in 1997. Cardiovascular diseases and cancer are among the leading causes of death in Mongolia.Nuclear Medicine in Mongolia-1975-1981 Beginning First Medical Application of radioisotopes in 1972. First Rectilinear scanner. Single and dual scintillation detectors system, Thyroid Uptake Test; 1982-1999 Settlement, IAEA TC Project since 1982, Thematic Program on Health Care (RAS) since 1997, First Gamma Camera since 1997, Radioimmunological Laboratory and first Radioiodine treatment since 1982, Mongolian Society of Nuclear Medicine since 1982, Member of World and Federation of Nuclear Medicine and Biology since 1994, Member of Asia and Oceania Radionuclide Therapy Council , 2000 Development, First SPECT and Quantitative Measurement in 2000 Second Gamma Camera, New Thyroid Uptake System-Atomlab 950 PC Spectrometer Radioimmunological Laboratory replacement, Myocardial Perfusion Scintigraphy, Liver Cancer Treatment with Re-188, Radiosynovectomy with Re

  2. Prospects in nuclear medicine

    International Nuclear Information System (INIS)

    In nuclear medicine, a sequence of revolutioning research up to the simple and efficient application in routine has always then taken place when in an interdisciplinary teamwork new radiochemical tracers and/or new instrumentation had become available. At present we are at the beginning of a phase that means to be in-vivo-biochemistry, the targets of which are molecular interactions in the form of enzymatic reactions, ligand-receptor interactions or immunological reactions. The possibility to use positron-emitting radionuclides of bioelements in biomolecules or drugs to measure their distribution in the living organism by positron-emission tomography (PET) is gaining admittance into the pretentious themes of main directions of medical research. Diagnostic routine application of biochemically oriented nuclear medicine methods are predominantly expected from the transmission of knowledge in PET research to the larger appliable emission tomography with gamma-emitting tracers (SPECT). (author)

  3. Imaging in nuclear medicine

    CERN Document Server

    Hoeschen, Christoph

    2013-01-01

    This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  4. Nuclear medicine and gastroenterology

    International Nuclear Information System (INIS)

    A Symposium with the topic 'Nuclear Medicine and Gastroenterology' was held on the occasion of the annual meeting 1976 of the Rheinisch-Westfalische Gesellschaft fuer Nuklearmedizin, led by Professor Dr.W. Stroetges in the Klinicum of the University of Essen. The meeting report first deals with some well-established examination methods which, however, still need some explanation concerning their diagnostical-patho-physiological background. Then some problems are shown which might be solved with the help of nuclear medicine. 1) Exsudative enteropathy, 2) The problem of the blind loop with bacteria proliferation and its relations to gall acid metabolism, 3) Functional examination of the distal small intestine with absorption of vitamin B12; 4) Some special problems. (orig.)

  5. Nuclear medicine therapy

    CERN Document Server

    Eary, Janet F

    2013-01-01

    One in three of the 30 million Americans who are hospitalized are diagnosed or treated with nuclear medicine techniques. This text provides a succinct overview and detailed set of procedures and considerations for patient therapy with unsealed radioactivity sources.  Serving as a complete literature reference for therapy with radiopharmaceuticals currently utilized in practice, this source covers the role of the physician in radionuclide therapy, and essential procedures and protocols required by health care personnel.

  6. Veterinary nuclear medicine

    International Nuclear Information System (INIS)

    The veterinary use of radionuclide techniques dates back to the mid-sixties, but its more extensive use dates back to the past two decades. Veterinary nuclear medicine is focused mainly on four major issues: bone scintigraphy - with the majority of applications in horses, veterinary endocrinology - dealing mainly with the problems of hyperthyreosis in cats and hyperthyreosis in dogs, portosystemic shunts in small animals and veterinary oncology, however, most radionuclide techniques applied to humans can be applied to most animals. (author)

  7. Imaging in nuclear medicine

    International Nuclear Information System (INIS)

    Presents the most recent developments in nuclear medicine imaging, with emphasis on the latest research findings. Considers the latest advances in imaging systems, image reconstruction, noise correction, and quality assurance. Discusses novel concepts, including those developed within the framework of the EURATOM FP7 MADEIRA project. Lists rules of thumb for imaging of use to both beginners and experienced researchers. This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  8. Imaging in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Giussani, Augusto [BfS - Federal Office for Radiation Protection, Oberschleissheim (Germany). Dept. of Radiation Protection and Health; Hoeschen, Christoph (eds.) [Helmholtz Zentrum Muenchen - German Research Center for Environmental Health, Neuherberg (Germany). Research Unit Medical Raditation Physics and Diagnostics

    2013-08-01

    Presents the most recent developments in nuclear medicine imaging, with emphasis on the latest research findings. Considers the latest advances in imaging systems, image reconstruction, noise correction, and quality assurance. Discusses novel concepts, including those developed within the framework of the EURATOM FP7 MADEIRA project. Lists rules of thumb for imaging of use to both beginners and experienced researchers. This volume addresses a wide range of issues in the field of nuclear medicine imaging, with an emphasis on the latest research findings. Initial chapters set the scene by considering the role of imaging in nuclear medicine from the medical perspective and discussing the implications of novel agents and applications for imaging. The physics at the basis of the most modern imaging systems is described, and the reader is introduced to the latest advances in image reconstruction and noise correction. Various novel concepts are then discussed, including those developed within the framework of the EURATOM FP7 MADEIRA research project on the optimization of imaging procedures in order to permit a reduction in the radiation dose to healthy tissues. Advances in quality control and quality assurance are covered, and the book concludes by listing rules of thumb for imaging that will be of use to both beginners and experienced researchers.

  9. Frontiers in nuclear medicine symposium: Nuclear medicine & molecular biology

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    This document contains the abstracts from the American College of Nuclear Physicians 1993 Fall Meeting entitled, `Frontiers in Nuclear Medicine Symposium: Nuclear Medicine and Molecular Biology`. This meeting was sponsored by the US DOE, Office of Health and Environmental Research, Office of Energy Research. The program chairman was Richard C. Reba, M.D.

  10. Nuclear medicine statistics

    International Nuclear Information System (INIS)

    Numerical description of medical and biologic phenomena is proliferating. Laboratory studies on patients now yield measurements of at least a dozen indices, each with its own normal limits. Within nuclear medicine, numerical analysis as well as numerical measurement and the use of computers are becoming more common. While the digital computer has proved to be a valuable tool for measurment and analysis of imaging and radioimmunoassay data, it has created more work in that users now ask for more detailed calculations and for indices that measure the reliability of quantified observations. The following material is presented with the intention of providing a straight-forward methodology to determine values for some useful parameters and to estimate the errors involved. The process used is that of asking relevant questions and then providing answers by illustrations. It is hoped that this will help the reader avoid an error of the third kind, that is, the error of statistical misrepresentation or inadvertent deception. This occurs most frequently in cases where the right answer is found to the wrong question. The purposes of this chapter are: (1) to provide some relevant statistical theory, using a terminology suitable for the nuclear medicine field; (2) to demonstrate the application of a number of statistical methods to the kinds of data commonly encountered in nuclear medicine; (3) to provide a framework to assist the experimenter in choosing the method and the questions most suitable for the experiment at hand; and (4) to present a simple approach for a quantitative quality control program for scintillation cameras and other radiation detectors

  11. Nuclear medicine radiation dosimetry

    CERN Document Server

    McParland, Brian J

    2010-01-01

    Complexities of the requirements for accurate radiation dosimetry evaluation in both diagnostic and therapeutic nuclear medicine (including PET) have grown over the past decade. This is due primarily to four factors: growing consideration of accurate patient-specific treatment planning for radionuclide therapy as a means of improving the therapeutic benefit, development of more realistic anthropomorphic phantoms and their use in estimating radiation transport and dosimetry in patients, design and use of advanced Monte Carlo algorithms in calculating the above-mentioned radiation transport and

  12. Nuclear medicine in vitro

    International Nuclear Information System (INIS)

    The subject is discussed under the following main headings: crystal scintillation counting; liquid scintillation counting; activation analysis; the in vitro nuclear medicine laboratory; blood volume in clinical practice B12 and folate deficiency; radionuclide studies associated with abnormalities of iron; basic principles of competitive radioassay; plasma cortisol; radioimmunoassays for T3 and T4; radioimmunoassay of estrogens; determination of androgens in biological fluids; radioimmunoassay of digitalis glycosides; growth hormone; thyrotropin; gonadotropins; radioimmunoassay of gastrin; glucagon; radioisotopic measurements of insulin; radioimmunoassay of the calcium-regulating hormones; the renin-angiotensin system and aldosterone; tumor antigens; fat absorption; protein-losing enteropathy; Australia antigen; bacteriologic cultures and sensitivities; and future pathways

  13. Nuclear medicine in cardiology

    Energy Technology Data Exchange (ETDEWEB)

    Torizuka, K.; Ishii, Y.; Yonekura, Y.; Yamamoto, K.; Tamaki, N. (Kyoto Univ. (Japan). Faculty of Medicine)

    1981-02-01

    Nuclear medicine in cardiology was reviewed. Electrocardiogram is obtained from the ..gamma..-ray measurement of a tracer by a single detector, which enables a bedsidemonitoring. Resolution and sensitivity are high and nuclear stethoscope with a computer is applicable for a background treatment. Myocardium is imaged by /sup 201/Tl scintigraphy. Relative difference of the perfusion indicates the ischemia which gaives roughly the size and portion of myocardial infarction. For transient ischemia stress myocardial perfusion imaging (SMPI) is also used. sup(99m)Tc pyrophosphate provides a clear image for myocardial infarction. Angiocardiogram is obtained repeatedly, by a single administration, using an equilibrium method. An attempt of three-dimensional display by 7 pin hole collimator and positron CT are also discussed.

  14. Nuclear medicine in cardiology

    International Nuclear Information System (INIS)

    Nuclear medicine in cardiology was reviewed. Electrocardiogram is obtained from the γ-ray measurement of a tracer by a single detector, which enables a bedsidemonitoring. Resolution and sensitivity are high and nuclear stethoscope with a computer is applicable for a background treatment. Myocardium is imaged by 201Tl scintigraphy. Relative difference of the perfusion indicates the ischemia which gaives roughly the size and portion of myocardial infarction. For transient ischemia stress myocardial perfusion imaging (SMPI) is also used. sup(99m)Tc pyrophosphate provides a clear image for myocardial infarction. Angiocardiogram is obtained repeatedly, by a single administration, using an equilibrium method. An attempt of three-dimensional display by 7 pin hole collimator and positron CT are also discussed. (Nakanishi, T.)

  15. Nuclear Medicine week in Colombia

    International Nuclear Information System (INIS)

    During the week of 6-12 October 2003 the IAEA organized a Research Coordination Meeting on 'Relationship between lower Respiratory Tract Infection, Gastroesophageal reflux and bronchial Asthma in children' at Hospital San Ignacio in Bogota. Besides there were four workshops in Bogota; workshops on Bone infection and Bone scan in Pediatric ortopaedics at Hospital Militar and Fundacion CardioInfantil, a workshop for Nuclear Medicine Technologists and a workshop on Sentinel Lymph Node mapping and Surgical Gamma Probe Application at Institute of Oncology. A nuclear cardiology workshop was organized in Medellin, and finally crowning them all was the 9th Congress of the Colombian Association of Nuclear Medicine at Cali from 10-12 October, 2003; probably the largest and best Colombian nuclear medicine congress every held in the country. A workshop was also organized in Cali for nuclear medicine technologists in conjunction with the Annual Convention. It was a mix of IAEA's Technical Cooperation and Regular Budget activities along with the activities of Colombian Association of Nuclear Medicine, bringing in absolute synergy to galvanize the entire nuclear medicine community of the country. The week saw nuclear medicine scientists from more than 20 IAEA Member States converging on Colombia to spread the message of nuclear medicine, share knowledge and to foster International understanding and friendship among the nuclear medicine people of the world

  16. Artificial intelligence as a diagnostic adjunct in cardiovascular nuclear imaging

    International Nuclear Information System (INIS)

    The radiologist and/or nuclear medicine physician is literally bombarded with information from today's diagnostic imaging technologies. As a consequence of this, whereas a decade ago the emphasis in medical image analysis was on improving the extraction of diagnostic information by developing and using more sophisticated imaging modalities, today those working on the development of medical imaging technology are struggling to find ways to handle all gathered information effectively. This chapter gives an introduction to the area of artificial intelligence, with an emphasis on the research ongoing in cardiovascular nuclear imaging. This chapter has reviewed the place of artificial intelligence in cardiovascular nuclear imaging. It is intended to provide a general sense of this new and emerging field, an insight into some of its specific methodologies and applications, and a closer look at the several AI approaches currently being applied in cardiovascular nuclear imaging

  17. Nuclear Medicine Imaging in the Pediatric Patient

    OpenAIRE

    Loveless, Vivian

    2006-01-01

    Pediatric nuclear medicine provides a wealth of information on a variety of disease states; however, precautions on dosing have to be taken into consideration. Also, expertise in conducting procedures and interpreting the results in pediatric patients is necessary. Emphasis is placed on diagnostic studies involving the central nervous system, musculoskeletal system, genitourinary system, gastrointestinal system, endocrine system, pulmonary system, and cardiovascular system along with a brief ...

  18. Nuclear medicine and AIDS

    International Nuclear Information System (INIS)

    The human immunodeficiency virus (HIV) infection and its associated illnesses in a relatively young population of patients provides an expanding role for nuclear medicine. The disease enforces a review of each department's infection control procedures. It has also resulted in an increase in the number of patients presenting with diseases such as Pneumocystis carinii pneumonia, Kaposi's sarcoma etc. which prior to the HIV epidemic were extremely rare. Thus in high risk patients the interpretation of abnormalities in nuclear medicine scans needs to include the spectrum of opportunistic infections and unusual tumours. The presence of opportunistic infections in the severely immunocompromised patient has led to the development of techniques not normally used, i.e. lung 99Tcm-diethylenetriamine pentaacetate (DTPA) transfer/clearance, donor leukocyte scanning to allow rapid diagnosis of an abnormality. Radionuclide techniques are also used to monitor the effect of therapy directed at the HIV itself or against opportunistic infections. This review covers aspects of infection control as well as the use of radionuclides to investigate specific problems related to HIV infection and therapy of the associated disease processes. (author)

  19. Nuclear medicine in psychiatry

    International Nuclear Information System (INIS)

    In the same way that the symptoms between different diseases in psychiatry overlap, functional brain research frequently shows the same pattern of changes across diagnostic borders; on the other hand, many the other tests, e.g. psychological tests, present the same problem as mentioned above; therefore: The psychiatrist seldom applies to an NM specialist to obtain a diagnosis; instead, a nuclear medicine report will rather confirm, or less frequently exclude, the psychiatrist's diagnosis. Ideally, psychiatric patients should be rescanned after the treatment, and changes in perfusion and/or metabolism discussed between psychiatrist and NM specialist. As shown above, there are few practical applications of nuclear medicine due to low specificity and low spatial resolution, although in the aspect of functional imaging it is still superior to CT/MRI, even in their functional modalities. On the other hand, its investigational potential is still growing, as there is no imaging technique in sight which could replace metabolic and receptor studies, and also because the scope of functional imaging in psychiatric diseases is spreading from its traditional applications, like dementia or depression, towards many poorly investigated fields e.g. hypnosis, suicidal behaviour or sleep disorders. (author)

  20. Nuclear medicine and neurology

    International Nuclear Information System (INIS)

    Methods of nuclear medicine are based on the use of radioactive isotopes bound to specific marker substances. Administered radioactive markers enter metabolic processes. SPET and PET cameras enable, with their detectors, to register gamma quanta resulting from isotope decay, transform the absorbed quanta into visible light and process the registered signals by means of a computer system. Thus the functions of a living organism can be observed at the molecular level. Special markers capable of crossing the haematin-cephalic barrier and targeting neural metabolic processes are used for visualization of brain perfusion and neurotransmission at SPET and PET, serving for defection of diseases. These procedures are of special significance for the diagnosis of neurodegenerative diseases where the diagnostic value of anatomical-structural methods like CT and conventional MRI is low and where timely administration of proper neuroprotecfive measures contributes to improved disease management. SPET studies of brain perfusion enable to make early diagnosis of Alzheimer's disease due to typical perfusion defects which appear at the preclinical stage and allow to distinguish this disease from other dementia syndromes. Parkinson's disease has a latent period of 3-4 years before the clinical signs appear. SPET with dopamine receptors visualizes striatal dopaminergic presynaptic hypofunction providing the diagnosis at the early stage. Procedures of nuclear medicine enable to establish the differential diagnosis of various Parkinsonian syndromes. SPET and PET research helps to understand better pathophysiological processes, pharmacokinetics and pharmacodynamics in living organisms.(authors)

  1. White paper of nuclear medicine

    International Nuclear Information System (INIS)

    This document aims at proposing a synthetic presentation of nuclear medicine in France (definition, strengths and weaknesses, key figures about practices and the profession, stakes for years to come), a description of the corresponding education (speciality definition, abilities and responsibilities, diploma content, proposition by the European Society of Radiology and by the CNIPI, demography of the profession), and an overview of characteristics of nuclear medicine (radio-pharmacy, medical physics, paramedical personnel in nuclear medicine, hybrid imagery, therapy, relationships with industries of nuclear medicine, relationships with health authorities)

  2. Nuclear Medicine Scans for Cancer

    Science.gov (United States)

    ... My ACS » Your Local Offices Close + - Text Size Nuclear Medicine Scans for Cancer Other names for these ... inflammation, or cancer. Use of monoclonal antibodies in nuclear scans A special type of antibody made in ...

  3. Nuclear power in human medicine

    International Nuclear Information System (INIS)

    The public widely associate nuclear power with the megawatt dimensions of nuclear power plants in which nuclear power is released and used for electricity production. While this use of nuclear power for electricity generation is rejected by part of the population adopting the polemic attitude of ''opting out of nuclear,'' the application of nuclear power in medicine is generally accepted. The appreciative, positive term used in this case is nuclear medicine. Both areas, nuclear medicine and environmentally friendly nuclear electricity production, can be traced back to one common origin, i.e. the ''Atoms for Peace'' speech by U.S. President Eisenhower to the U.N. Plenary Assembly on December 8, 1953. The methods of examination and treatment in nuclear medicine are illustrated in a few examples from the perspective of a nuclear engineer. Nuclear medicine is a medical discipline dealing with the use of radionuclides in humans for medical purposes. This is based on 2 principles, namely that the human organism is unable to distinguish among different isotopes in metabolic processes, and the radioactive substances are employed in amounts so small that metabolic processes will not be influenced. As in classical medicine, the application of these principles serves two complementary purposes: diagnosis and therapy. (orig.)

  4. Nuclear medicine pulmonary diagnosis

    International Nuclear Information System (INIS)

    Scintigraphic recording of regional ventilation and perfusion with 99mTc-Aerosol and 99mTc-MAA remain in the foreground of nuclear medicine pulmonary diagnostics. The most important indication for ventilation scintigraphy is the prediction of postoperative pulmonary function, which is still performed in many hospitals with perfusion scintigraphy, and with which, in turn, intrapulmonary right-left shunts can be simply and also semiquantitatively recorded. Combined ventilation/perfusion scintigraphy offers a very high degree of sensitivity in the proof of acute pulmonary embolism, is therefore exceptionally well suited for exclusion diagnostics, while specificity compared to pulmonary angiography and spiral CT still needs some clarification. The self-cleaning mechanism of the lung can be quantitatively examined using mucociliary and resorptive clearance. The clinical areas of application are limited for methodical reasons. Primary diagnostics of bronchial carcinoma and dignity differentiation of solitary pulmonary nodules, preferably with 18F-FDG PET are gaining steadily in importance. (orig.)

  5. Nuclear medicine and radiopharmacy

    International Nuclear Information System (INIS)

    In the areas of Nuclear Medicine and Radiopharmacy frequently happens that the personnel that is incorporated as a candidate to serve as personnel occupationally exposed have varied skills, not necessarily have an ingrained culture of safety and radiation protection, some are resistant to adoption a work discipline and have very limited notions of normalization, including the safety basic standards. In fact, referring to the safety basic standards, concepts such as practice justification, protection optimization and dose limitation, can be very abstract concepts for such personnel. In regard to training strategies, it was noted that training in the work is an effective tool although it is very demanding for the learner but mainly for the teaches. The experts number that can occur in this manner is limited because it is an individualized system; however those from the process usually acquire a good preparation, which certainly includes theoretical aspects. For greater efficiency it is necessary that hospitals account facilities, procedures and personnel that might have an exclusive dedication to education and training of human resources. This would create a safety culture, alleviating the burdens of the already existing expertise and improves the training conditions. The Mexican Society of Radiological Safety (SMSR) can help in these efforts through the publication of guides aimed at work training, coordination and articulation of the possible courses already on the market and own the courses organization, workshops and conferences with more frequency. It would also serves that the SMSR acts as speaker with political actors, advocating for the courses validation offered by higher learning institutions, coordinating and promoting postgraduates in Nuclear Medicine and Radiopharmacy. (Author)

  6. Asian School of Nuclear Medicine

    International Nuclear Information System (INIS)

    A number of organisations are involved in the field of nuclear medicine education. These include International Atomic Energy Agency (IAEA), World Federation of Nuclear Medicine and Biology (WFNMB), Asia-Oceania Federation of Nuclear Medicine and Biology (AOFNMB), Society of Nuclear Medicine (SNM in USA), European Association of Nuclear Medicine (EANM). Some Universities also have M.Sc courses in Nuclear Medicine. In the Asian Region, an Asian Regional Cooperative Council for Nuclear Medicine (ARCCNM) was formed in 2000, initiated by China, Japan and Korea, with the main aim of fostering the spread of Nuclear Medicine in Asia. The Asian School of Nuclear Medicine (ASNM) was formed in February 2003, with the ARCCNM as the parent body. The Aims of ASNM are: to foster Education in Nuclear Medicine among the Asian countries, particularly the less developed regions; to promote training of Nuclear Medicine Physicians in cooperation with government agencies, IAEA and universities and societies; to assist in national and regional training courses, award continuing medical education (CME) points and provide regional experts for advanced educational programmes; and to work towards awarding of diplomas or degrees in association with recognised universities by distance learning and practical attachments, with examinations. There are 10 to 12 teaching faculty members from each country comprising of physicists, radio pharmacists as well as nuclear medicine physicians. From this list of potential teaching experts, the Vice-Deans and Dean of ASNM would then decide on the 2 appropriate teaching faculty member for a given assignment or a course in a specific country. The educational scheme could be in conjunction with the ARCCNM or with the local participating countries and their nuclear medicine organisations, or it could be a one-off training course in a given country. This teaching faculty is purely voluntary with no major expenses paid by the ASNM; a token contribution could be

  7. Essentials of nuclear medicine imaging

    CERN Document Server

    Mettler, Fred A. Jr

    2012-01-01

    Essentials of Nuclear Medicine Imaging, by Drs. Fred A Mettler and Milton J Guiberteau, provides the practical and comprehensive guidance you need to master key nuclear imaging techniques. From physics, instrumentation, quality control, and legal requirements to hot topics such as sodium fluoride, radiopharmaceuticals, and recommended pediatric administered doses and guidelines, this sixth edition covers the fundamentals and recent developments in the practice of nuclear medicine.

  8. Nuclear Medicine in Surgical Oncology

    International Nuclear Information System (INIS)

    Defines nuclear medicine as a branch that utilizes nuclear technology for diagnosis and treatment of diseases.The principles of nuclear medicine are; it uses the principle that a certain radiopharmaceutical (tracer) will at a certain point in time have a preferential uptake by a particular body or tissue. it is imaged by use the use of detectors mounted in gamma cameras or PET (Position emission tomography) devices

  9. Maladministrations in nuclear medicine

    International Nuclear Information System (INIS)

    Maladministration has been defined as the mistaken administration of a radiopharmaceutical to a patient. Examples include the administration of the wrong radiopharmaceutical or the wrong activity to the correct patient or the administration of the correct radiopharmaceutical to the wrong patient. Although maladministrations are rare, lessons can be learnt from the incidents that do occur. Medical maladministrations and other radiation incidents are discussed by members of the NSW Hospital and University Radiation Safety Officers Group (HURSOG) at their bi-monthly meetings. During the three years of 1997-1999 fourteen incidents of maladministrations in nuclear medicine were reported. Analysis of these reports indicated that eight (57 %) were due to the wrong radiopharmaceutical having been administered. This usually occurred because the technologist had selected the wrong lyophilised agent when the radiopharmaceutical was being prepared, or selected the wrong vial of the reconstituted agent. For example, in one instance a vial of MAG3 was reconstituted instead of a vial of HMPAO. These mistakes occurred even though the vials were clearly labelled and sometimes had different coloured labels. Of the remaining 6 cases, two involved the wrong activity being administered due to a mis-read dose calibrator, two involved the wrong procedure being performed following a breakdown in communication and the final two incidents resulted in the wrong patient being administered the radiopharmaceutical. In order to minimise the possibility of recurrence of these incidents the NSW Radiation Advisory Council asked the NSW Branch of the Australian and New Zealand Society of Nuclear Medicine and HURSOG to jointly convene a Working Party to prepare Guidelines for the administration of radiopharmaceuticals. The Guidelines specify: 1. the procedure for the validation of the requested investigation on the request form 2. who should reconstitute, dispense and administer radiopharmaceuticals

  10. Complementary alternative medicine and nuclear medicine

    International Nuclear Information System (INIS)

    Complementary alternative medicines (CAMs), including food supplements, are taken widely by patients, especially those with cancer. Others take CAMs hoping to improve fitness or prevent disease. Physicians (and patients) may not be aware of the potential side-effects and interactions of CAMs with conventional treatment. Likewise, their known physiological effects could interfere with radiopharmaceutical kinetics, producing abnormal treatment responses and diagnostic results. Nuclear medicine physicians are encouraged to question patients on their intake of CAMs when taking their history prior to radionuclide therapy or diagnosis. The potential effect of CAMs should be considered when unexpected therapeutic or diagnostic results are found. (orig.)

  11. Nuclear medicine in oncology

    International Nuclear Information System (INIS)

    Cancer is increasingly prevalent in our society. There is a life-time risk that 1 in 3 Australian men and 1 in 4 Australian women will get cancer before the age of 75 years. Overall, 27% of the deaths in NSW are currently related to cancer. The common cancers for men are prostate, lung, melanoma, colon, rectum and bladder. For women the common cancers are breast, colon, melanoma, lung and unknown primary. However, overall lung cancer remains the major cause of cancer deaths (20%) followed by colorectal (13%), unknown site (8%), breast and prostate. Breast and lung cancer are the major causes of death in women. Recent information on 5 year survivals reveal good 5 year survival rates for breast (78.6%), prostate (72.4%) and melanoma (92%), while some tumours such as lung cancer (10.7%) have poor survival. Colon cancer has intermediate survival (57.1%). Projections for cancer incidence suggests rates of cancer will increase for colorectal cancer, melanoma, lung cancer in females but decrease for breast, lung in males and prostate cancer. Major strategic directions in cancer research are understanding carcinogenesis, identification of high risk groups, screening and early detection, chemo-prevention, new cancer therapies, combined modality therapy and quality of life issues. Nuclear medicine will play an important part in many of these areas

  12. Future of nuclear medicine

    International Nuclear Information System (INIS)

    When it comes to setting up nuclear medicine in a developing country, there is a group of people, who feel that such high technology has no place in a developing country. RIA is likely to remain the method of choice for the research laboratory. The use of radioisotopic label has many advantages compared to the use of an enzyme marker. Generally, iodination is simpler than the preparation of an enzyme labelled substance, especially since there has been no agreement as to which enzyme is best for substances as small as steroids or a large as viruses. In addition, there may be some change in the configuration of the enzyme or the substance to be labelled during the conjugation procedure. Monoclonal antibodies can provide virtually unlimited amounts of homogenous antibodies against a specific antigenic site. The heterogeneous antibodies are more likely to provide more sensitive assays than the monoclonal antibodies, although assays employing the latter are likely to be more specific. The optimal choice of the antiserum may depend on whether sensitivity or specificity is required for the assays

  13. Nuclear medicine in pediatrics

    International Nuclear Information System (INIS)

    A brief review is done of radionuclide applications in pediatrics. The following subjects are commented: radioisotopic investigations of cardiovascular system; pulmonary system; liver; urinary tract; brain; subarachnoide space; thyroid and skeleton. (M.A.)

  14. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Pediatric Ultrasound Video: Angioplasty & vascular stenting Video: Arthrography Radiology and You About this Site RadiologyInfo.org is ... Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! I’m Dr. Ramji ...

  15. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... before abnormalities can be detected with other diagnostic tests. Nuclear medicine imaging procedures use small amounts of radioactive materials – called radiotracers – that are typically injected into the ...

  16. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... Angioplasty & vascular stenting Video: Arthrography Video: Contrast Material Radiology and You Take our survey About this Site ... Your Radiologist Explains Nuclear Medicine Transcript Welcome to Radiology Info dot org Hello! I’m Dr. Ramji ...

  17. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... relatively low and the benefit of an accurate diagnosis far outweighs any risk. To learn more about nuclear medicine, visit Radiology Info dot org. Thank you for your time! ...

  18. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... If you’re scheduled for a nuclear medicine exam, there are several things you can do to ... to refrain from taking certain medications before the exam. Also, it’s best to leave any jewelry at ...

  19. Two-modality γ detection of blood volume by camera imaging and nonimaging stethoscope for kinetic studies of cardiovascular control in nuclear medicine

    Science.gov (United States)

    Eclancher, Bernard; Chambron, Jacques; Dumitresco, Barbu; Karman, Miklos; Pszota, Agnes; Simon, Atilla; Didon-Poncelet, Anna; Demangeat, Jean

    2002-04-01

    The quantification of rapid hemodynamic reactions to wide and slow breathing movements has been performed, by two modalities (gamma) -left ventriculography of 99mTc-labeled blood volume, in anterior oblique incidence on standing and even exercising healthy volunteers and cardiac patients. A highly sensitive stethoscope delivered whole (gamma) -counts acquired at 30 msec intervals in a square field of view including the left ventricle, in a one dimensional low resolution imaging mode for beat to beat analysis. A planar 2D (gamma) -camera imaging of the same cardiac area was then performed without cardiac gating for alternate acquisitions during deep inspiration and deep expiration, completed by a 3D MRI assessment of the stethoscope detection field. Young healthy volunteers displayed wide variations of diastolic times and stroke volumes, as a result of enhanced baroreflex control, together with +/- 16% variations of the stethoscope's background blood volume counts. Any of the components of these responses were shifted, abolished or even inverted as a result of either obesity, hypertension, aging or cardiac pathologies. The assessment of breathing control of the cardiovascular system by the beat to beat (gamma) -ventriculography combined with nuclear 2D and 3D MRI imaging is a kinetic method allowing the detection of functional anomalies in still ambulatory patients.

  20. Radiation protection in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Mattsson, Soeren [Lund Univ., Skane Univ. Hospital Malmoe (Sweden). Medical Radiation Physics; Hoeschen, Christoph (eds.) [Helmholtz Zentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt GmbH, Neuherberg (Germany)

    2013-07-01

    Addresses all aspects of radiation protection in nuclear medicine. Covers current technologies and principles. An ideal textbook for students and a ready source of information for nuclear medicine specialists and medical physics experts. One of a series of three books on the fundamentals of modern nuclear medicine (physics, safety, and imaging). This book explains clearly and in detail all aspects of radiation protection in nuclear medicine. After an introductory chapter on the general role of radiation protection, measurement quantities and units are discussed, and detectors and dosimeters, described. Radiation biology and radiation dosimetry are then addressed, with the inclusion of a chapter specifically devoted to biology and dosimetry for the lens of the eye. Discussion of radiation doses to patients and to embryos, fetuses, and children forms a central part of the book. Phantom models, biokinetic models, calculations, and software solutions are all considered, and a further chapter focuses on quality assurance and reference levels. Occupational exposure also receives detailed attention. Exposure resulting from the production, labeling, and injection of radiopharmaceuticals and from contact with patients is discussed and shielding calculations are explained. The book closes by considering exposure of the public and summarizing the ''rules of thumb'' for radiation protection in nuclear medicine. This is an ideal textbook for students and a ready source of useful information for nuclear medicine specialists and medical physics experts.

  1. Children's (Pediatric) Nuclear Medicine

    Medline Plus

    Full Text Available ... medicine will interpret the images and forward a report to your referring physician. top of page What ... by: Please note RadiologyInfo.org is not a medical facility. Please contact your physician with specific medical ...

  2. Nuclear Medicine Imaging

    Science.gov (United States)

    ... necesita saber acerca de... Estudios de Imagen de Medicina Nuclear Un procedimiento de medicina nuclear se describe algunas veces como unos rayos- ... través del cuerpo del paciente. Los procedimientos de medicina nuclear utilizan pequeñas cantidades de mate- riales radiactivos, ...

  3. Nuclear medicine imaging and therapy: gender biases in disease.

    Science.gov (United States)

    Moncayo, Valeria M; Aarsvold, John N; Alazraki, Naomi P

    2014-01-01

    Gender-based medicine is medical research and care conducted with conscious consideration of the sex and gender differences of subjects and patients. This issue of Seminars is focused on diseases for which nuclear medicine is part of routine management and for which the diseases have sex- or gender-based differences that affect incidence or pathophysiology and that thus have differences that can potentially affect the results of the relevant nuclear medicine studies. In this first article, we discuss neurologic diseases, certain gastrointestinal conditions, and thyroid conditions. The discussion is in the context of those sex- or gender-based aspects of these diseases that should be considered in the performance, interpretation, and reporting of the relevant nuclear medicine studies. Cardiovascular diseases, gynecologic diseases, bone conditions such as osteoporosis, pediatric occurrences of some diseases, human immunodeficiency virus-related conditions, and the radiation dose considerations of nuclear medicine studies are discussed in the other articles in this issue. PMID:25362232

  4. THERAPEUTIC APPLICATIONS IN NUCLEAR MEDICINE

    Directory of Open Access Journals (Sweden)

    Cristofer Alan Costa Santos

    2014-12-01

    Full Text Available Due to poor understanding of the role of nuclear medicine in several disease treatments, the aim of this study was to demonstrate the main therapeutic applications of nuclear medicine as well as their characteristics and radiopharmaceuticals usage through scientific literature review. The main therapeutic applications of nuclear medicine are radio-immunotherapy with iodine-131, yttrium-90, lutetium-177 and copper-67, the radiosynovectomy with yttrium-90, rhenium-186 and gold-198 and pain palliation of osseous metastases with samarium-153, strontium-89 and phosphorus-32. The radioiodine therapy with iodine-131 stands out among therapies because it allows a highly selective treatment of thyroid associated with hyperthyroidism and differentiated thyroid cancer with favorable dosimetry to healthy tissues and with great advantage to allow the ablation of disseminated lesions due to metastases, success not achieved by traditional radiotherapy. Thus, the therapeutic nuclear medicine is an alternative tool, and often essential for definitive treatment of various diseases considered incurable once. Thus, therapeutic nuclear medicine is an alternative and often essential tool for definitive treatment of various diseases considered once incurable.

  5. Neuroimaging, nuclear medicine

    International Nuclear Information System (INIS)

    This chapter describes radionuclide imaging as it related to neurodegenerative dementias like Alzheimer's disease (AD), idiopathic Parkinson's disease (PD), and normal aging, among the various diseases of the elderly. The role of neuroimaging with nuclear medicine is to detect changes in neural activities that are caused by these diseases. Such changes may be indirect phenomena, but the imaging of neural functions provides physicians with useful, objective information regarding pathophysiology in the brain. Brain activities change with age, with the elderly showing decreased brain function in memory, execution, and attention. Age-dependent reduction in the global mean of cerebral blood flow (CBF) has been reported in many studies that have used X-133 and O-15 labeled gas, the spatial resolution of which is low. Partial volume correction (PVC) is available through the segmentation of grey matter from high-resolution T1-weighted magnetic resonance imaging. Meltzer reported that age-related change disappeared after PVC. The relative distribution of CBF and glucose metabolism has been examined on a voxel-by-voxel basis in many studies. The areas negatively correlated with age are the anterior part of the brain, especially the dorsolateral and medial frontal areas, anterior cingulate cortices, frontolateral and perisylvian cortices, and basal ganglia. The areas positively correlated with age are the occipital lobe, temporal lobe, sensorimotor cortex, and primary visual cortex. It is not easy to define ''normal aging''. Aged people tend to have the potential for diseases like cerebral ischemia caused by arteriosclerosis. Ischemia results in volume loss of the gray matter and CBF. The ApoE e4 gene is a risk factor for AD, and carriers of the ApoE e4 allel show CBF-like AD even at a relatively young age. Hypo-glucose metabolism in the posterior cingulate cortex is seen in 5% of normal people over 50 years of age. This Alzheimer-like CBF/metabolic pattern needs further

  6. Nuclear medicine - no. 3

    International Nuclear Information System (INIS)

    This bulletin contains seven articles relating to the isotopic applications in medicine. Their subject matter ranges from the preparation of radiopharmaceuticals through their application in scintiscanning to computer codes for evaluation of the results. The individual articles have been indexed separately

  7. Radiation physics for nuclear medicine

    CERN Document Server

    Hoeschen, Christoph

    2011-01-01

    The field of nuclear medicine is expanding rapidly, with the development of exciting new diagnostic methods and treatments. This growth is closely associated with significant advances in radiation physics. In this book, acknowledged experts explain the basic principles of radiation physics in relation to nuclear medicine and examine important novel approaches in the field. The first section is devoted to what might be termed the "building blocks" of nuclear medicine, including the mechanisms of interaction between radiation and matter and Monte Carlo codes. In subsequent sections, radiation sources for medical applications, radiopharmaceutical development and production, and radiation detectors are discussed in detail. New frontiers are then explored, including improved algorithms for image reconstruction, biokinetic models, and voxel phantoms for internal dosimetry. Both trainees and experienced practitioners and researchers will find this book to be an invaluable source of up-to-date information.

  8. Nuclear Medicine on the net

    International Nuclear Information System (INIS)

    Full text: To gain insight into Internet usage as a potential means of communicating with clinicians. Method: 200 clinicians within the South Western Sydney Health Area were surveyed by mail. Questionnaire details included Internet access, frequency of access, interest in department web site, suitability of content and interest in electronic bookings. The total response rate was 37% (74/200). General Practitioners comprised 46% of the respondents, and specialists 54%. All respondents had access to the Internet (44% from home only, 8% from work, 48% from both locations), with 57% accessing the Web daily. There was a high overall interest by respondents in accessing a Nuclear medicine web site, particularly for information and results, but a relative reluctance to consider electronic bookings. The following table outlines the respondents in detail. Our results indicate that a Nuclear Medicine web site has the potential to be an effective means of communicating with clinicians. Copyright (2003) The Australian and New Zealand Society of Nuclear Medicine Inc

  9. Radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    Radiation protection in nuclear medicine in this project is concerned with the reduction of doses to workers, patients and members of the public. Protection of workers is achieved by adopting good personal habits, good housekeeping, proper use of personal protective devices and equipment, attend training and have continuous education. Exposure to radiation of workers and the members of the public are minimised by proper management of radioactive waste and safe transport of radioactive material. The design and shielding of a nuclear medicine department shall further provide for the protection of the worker, the patient and the general public. Protection of patient is achieved by justifying the procedure, delivering the minimum radiation dose possible to the patient while obtaining the best image quality and applying guidance levels. Special considerations shall be given to pregnant and breast-feeding patients. Quality assurance programme through image quality, radiopharmaceutical quality and patient records on nuclear medicine procedures shall provide assurance to the patient. (au)

  10. Cardiovascular and Hematological Medicine in 2013 - Advances and Insights.

    Science.gov (United States)

    Mukherjee, Debabrata

    2012-12-11

    Welcome to the first issue of Cardiovascular & Hematological Agents in Medicinal Chemistry (CHAMC) for 2013. I hope everyone has had an enjoyable holiday season and I want to wish everyone a wonderful New Year. As you know, our journal (CHAMC) aims to cover the latest and outstanding developments in medicinal chemistry, rational drug design for the discovery of novel cardiovascular and hematological Agents and discusses such therapies in clinical practice. Each issue contains a series of timely in-depth reviews, original research articles and drug clinical trial studies written by leaders in the field covering a range of current topics in cardiovascular and hematological sciences. I feel that CHAMC is an essential journal for every medicinal chemist, clinician and healthcare provider who wishes to be kept informed and up-to-date with the latest and most important developments in cardiovascular and hematological drug discovery and their clinical uses. In the coming issues of the journal, we will discuss several important topics pertinent to chemists and clinicians in the cardiovascular and hematology fields such as curcumin and resveratrol as alternative medicinal agents against metabolic syndrome, interrelationship between chronic kidney disease and risk of cardiovascular diseases and effects of direct renin inhibitor, aliskiren, on arterial hypertension, chronic kidney disease and cardiovascular disease among others. The journal also delves into hot topics such as genetic testing and personalized medicine, use of literature-based discovery to identify novel therapeutic approaches, pharmacologic mechanism and clinical relevance of P2Y12 inhibitors and intracoronary injection of glycoprotein IIb/IIIa, abciximab, as adjuvant therapy in primary coronary intervention. Cardiovascular medicine and hematology are both very dynamic fields with rapid advances and we will continue to work to keep you up to date on new advances and therapies. I would also take this

  11. Historic images in nuclear medicine

    DEFF Research Database (Denmark)

    Hess, Søren; Høilund-Carlsen, Poul Flemming; Alavi, Abass

    2014-01-01

    In 1976, 2 major molecular imaging events coincidentally took place: Clinical Nuclear Medicine was first published in June, and in August researchers at the Hospital of the University of Pennsylvania created the first images in humans with F-FDG. FDG was initially developed as part of an evolution...... set in motion by fundamental research studies with positron-emitting tracers in the 1950s by Michel Ter-Pegossian and coworkers at the Washington University. Today, Clinical Nuclear Medicine is a valued scientific contributor to the molecular imaging community, and FDG PET is considered the backbone...

  12. DEVELOPMENT AND INNOVATION IN CARDIOVASCULAR MEDICINE

    OpenAIRE

    DESMOND SHERIDAN

    2007-01-01

    The last century has witnessed groundbreaking advances in clinical medicine across the entire diagnostic and therapeutic range, but inequities in access to these advances and innovations continue to be a major challenge to our societies.Innovations are often initiated by "eureka" moments of discovery, but realising their full potential depend on a process of continuous incremental innovation and interaction involving complex networks. When developing systems that reward, encourage, and sustai...

  13. Opportunities for the Cardiovascular Community in the Precision Medicine Initiative.

    Science.gov (United States)

    Shah, Svati H; Arnett, Donna; Houser, Steven R; Ginsburg, Geoffrey S; MacRae, Calum; Mital, Seema; Loscalzo, Joseph; Hall, Jennifer L

    2016-01-12

    The Precision Medicine Initiative recently announced by President Barack Obama seeks to move the field of precision medicine more rapidly into clinical care. Precision medicine revolves around the concept of integrating individual-level data including genomics, biomarkers, lifestyle and other environmental factors, wearable device physiological data, and information from electronic health records to ultimately provide better clinical care to individual patients. The Precision Medicine Initiative as currently structured will primarily fund efforts in cancer genomics with longer-term goals of advancing precision medicine to all areas of health, and will be supported through creation of a 1 million person cohort study across the United States. This focused effort on precision medicine provides scientists, clinicians, and patients within the cardiovascular community an opportunity to work together boldly to advance clinical care; the community needs to be aware and engaged in the process as it progresses. This article provides a framework for potential involvement of the cardiovascular community in the Precision Medicine Initiative, while highlighting significant challenges for its successful implementation. PMID:27028435

  14. Pulmonary nuclear medicine

    International Nuclear Information System (INIS)

    This article reviews the contribution made by nuclear imaging to the assessment, diagnosis and monitoring of patients with respiratory disease. It focuses on several specific areas including the diagnosis of pulmonary embolism, the investigation of intrapulmonary infection and neoplasm and the role positron emission tomography (PET) scanning. (orig.)

  15. Your Radiologist Explains Nuclear Medicine

    Medline Plus

    Full Text Available ... through the area being examined and gives off energy in the form of gamma rays which are detected by a special camera and computer to create images of the inside of your body. If you’re scheduled for a nuclear medicine exam, there are several things you can ...

  16. Nuclear medicine at the crossroads

    Energy Technology Data Exchange (ETDEWEB)

    Strauss, H.W. [Stanford Univ. Hospital, Div. of Nuclear Medicine, CA (United States)

    1996-06-01

    Many nuclear medicine procedures, originally developed more than 20 years ago, are now performed with new radiopharmaceuticals or instruments; it is therefore apposite to reappraise what we are doing and why we are doing it. The clinical utility of nuclear medicine is discussed with reference, by way of example, to gated blood pools scans and myocardial perfusion imaging; the importance of the referred population for the outcome of studies is stressed. Attention is drawn to the likelohood that the detection of ischemia would be enhanced by the administration of nitroglycerin prior to rest thallium injection. Emphasis is also placed on the increasing acceptance of dual-tracer studies. The significance of expression of p-glycoprotein by some tumors for sestamibi imaging is discussed, and advances in respect of fluorodeoxyglucose imaging are reviewed. The final section covers issues relating to the development of new procedures, such as the value of nuclear medicine in the detection and characterization of tissue oxygen levels and the possible future role of nuclear medicine in the management of sleeping and eating disorders. (orig.)

  17. Nuclear medicine at the crossroads

    International Nuclear Information System (INIS)

    Many nuclear medicine procedures, originally developed more than 20 years ago, are now performed with new radiopharmaceuticals or instruments; it is therefore apposite to reappraise what we are doing and why we are doing it. The clinical utility of nuclear medicine is discussed with reference, by way of example, to gated blood pools scans and myocardial perfusion imaging; the importance of the referred population for the outcome of studies is stressed. Attention is drawn to the likelohood that the detection of ischemia would be enhanced by the administration of nitroglycerin prior to rest thallium injection. Emphasis is also placed on the increasing acceptance of dual-tracer studies. The significance of expression of p-glycoprotein by some tumors for sestamibi imaging is discussed, and advances in respect of fluorodeoxyglucose imaging are reviewed. The final section covers issues relating to the development of new procedures, such as the value of nuclear medicine in the detection and characterization of tissue oxygen levels and the possible future role of nuclear medicine in the management of sleeping and eating disorders. (orig.)

  18. Evolution of nuclear medicine: a historical perspective

    International Nuclear Information System (INIS)

    The field Nuclear Medicine has Completed its 100 yeas in 1996. Nuclear medicine began with physics, expanded into chemistry and instrumentation, and then greatly influenced various fields of medicine. The chronology of the events that formulated the present status of nuclear medicine involves some of the great pioneers of yesterday like Becquerel, Curie, Joliot, Hevesy, Anger, Berson and Yallow. The field of nuclear medicine has been regarded as the bridge builder between various aspects of health care and within next 20 years, nuclear medicine enters a new age of certainty, in which surgery, radiation and chemotherapy will only be used when a benefit in certain to result from the treatment. (author)

  19. A concise guide to nuclear medicine

    CERN Document Server

    Elgazzar, Abdelhamid H

    2011-01-01

    Nuclear medicine is an important component of modern medicine. This easy-to-use book is designed to acquaint readers with the basic principles of nuclear medicine, the instrumentation used, the gamut of procedures available, and the basis for selecting specific diagnostic or therapeutic procedures and interpreting results. After an introductory chapter on the history, technical basis, and scope of nuclear medicine, a series of chapters are devoted to the application of nuclear medicine techniques in the different body systems. In addition, the use of nuclear medicine methods within oncology is

  20. Physics and radiobiology of nuclear medicine

    CERN Document Server

    Saha, Gopal B

    2013-01-01

    The Fourth Edition of Dr. Gopal B. Saha’s Physics and Radiobiology of Nuclear Medicine was prompted by the need to provide up-to-date information to keep pace with the perpetual growth and improvement in the instrumentation and techniques employed in nuclear medicine since the last edition published in 2006. Like previous editions, the book is intended for radiology and nuclear medicine residents to prepare for the American Board of Nuclear Medicine, American Board of Radiology, and American Board of Science in Nuclear Medicine examinations, all of which require a strong physics background. Additionally, the book will serve as a textbook on nuclear medicine physics for nuclear medicine technologists taking the Nuclear Medicine Technology Certification Board examination.

  1. Therapeutic nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Baum, Richard P. (ed.) [ENETS Center of Excellence, Bad Berka (Germany). THERANOSTICS Center for Molecular Radiotherapy and Molecular Imaging

    2014-07-01

    Discusses all aspects of radionuclide therapy, including basic principles, newly available treatments, regulatory requirements, and future trends. Provides the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Explains the role of the therapeutic nuclear physician in effectively coordinating a diverse multidisciplinary team. Written by leading experts. The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. The selective irradiation of tumor cells through molecular biological mechanisms is now permitting the radiopharmaceutical control of tumors that are unresectable and unresponsive to either chemotherapy or conventional radiotherapy. In this up-to-date, comprehensive book, world-renowned experts discuss the basic principles of radionuclide therapy, explore in detail the available treatments, explain the regulatory requirements, and examine likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the important role of the therapeutic nuclear physician in delivering the effective coordination of a diverse multidisciplinary team that is essential to the safe provision of treatment.

  2. Therapeutic nuclear medicine

    International Nuclear Information System (INIS)

    Discusses all aspects of radionuclide therapy, including basic principles, newly available treatments, regulatory requirements, and future trends. Provides the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Explains the role of the therapeutic nuclear physician in effectively coordinating a diverse multidisciplinary team. Written by leading experts. The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. The selective irradiation of tumor cells through molecular biological mechanisms is now permitting the radiopharmaceutical control of tumors that are unresectable and unresponsive to either chemotherapy or conventional radiotherapy. In this up-to-date, comprehensive book, world-renowned experts discuss the basic principles of radionuclide therapy, explore in detail the available treatments, explain the regulatory requirements, and examine likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the important role of the therapeutic nuclear physician in delivering the effective coordination of a diverse multidisciplinary team that is essential to the safe provision of treatment.

  3. Neutron use in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Guidez, J.; May, R.; Moss, R. [HFR-Unit, European Commission, IAM, Petten (Netherlands); Askienazy, S. [Departement Central de Medicine Nucleaire et Biophysique, Saint Antoine Hospital, Paris (France); Hildebrand, J. [Neurology Department, Erasmus Hospital, Brussels (Belgium)

    1999-07-01

    Neutrons produced by research reactors are being used in nuclear medicine and other medical applications in several ways. The High Flux Reactor (HFR) based in Petten (The Netherlands), owned by the European Commission, has been working increasingly in this field of health care for the European citizen. On the basis of this experience, a survey has been carried out on the main possibilities of neutrons used in nuclear medicine. The most important and most well known is the production of radioisotopes for diagnosis and therapy. Ten million patients receive nuclear medicine in Europe each year, with more than 8 million made with the products issued from research reactors. The survey of the market and the techniques (cyclotron, PET) shows that this market will continue to increase in the future. The direct use of reactors in medicine is actually made by the Boron Neutron capture Therapy (BNCT) for the treatment of glioblastoma, which kills about 15.000 people in Europe each year. For this promising technique, HFR is the most advanced for experimental possibilities and treatment studies. Medical research is also made in other promising fields: the use beam tubes for characterizing of prostheses and bio-medical materials, alpha-immuno therapy products, new types of radioisotopes, new types of illness to be treated by BNCT, etc. (author)

  4. Essentials of nuclear medicine physics and instrumentation

    CERN Document Server

    Powsner, Rachel A; Powsner, Edward R

    2013-01-01

    An excellent introduction to the basic concepts of nuclear medicine physics This Third Edition of Essentials of Nuclear Medicine Physics and Instrumentation expands the finely developed illustrated review and introductory guide to nuclear medicine physics and instrumentation. Along with simple, progressive, highly illustrated topics, the authors present nuclear medicine-related physics and engineering concepts clearly and concisely. Included in the text are introductory chapters on relevant atomic structure, methods of radionuclide production, and the interaction of radiation with matter. Fu

  5. Phytotherapy in Cardiovascular Diseases: From Ethnomedicine to Evidence Based Medicine

    OpenAIRE

    Ovidiu Burta; Felicia Tirlea; Olivia Ligia Burta; Syed Minnatullah Qadri

    2008-01-01

    Cardiovascular diseases are now considered to be one of the major causes of mortality in the developed and developing world. With the advent of better diagnostic procedures and therapeutic strategies their management has become more efficient, yet the role of herbal and plant remedies is paramount in the developing and remote areas of the world. Phytotherapy or therapeutics using plants and herb based compounds or crude drugs are an indispensable part of Complementary and Alternative Medicine...

  6. Phytotherapy in Cardiovascular Diseases: From Ethnomedicine to Evidence Based Medicine

    Directory of Open Access Journals (Sweden)

    Ovidiu Burta

    2008-01-01

    Full Text Available Cardiovascular diseases are now considered to be one of the major causes of mortality in the developed and developing world. With the advent of better diagnostic procedures and therapeutic strategies their management has become more efficient, yet the role of herbal and plant remedies is paramount in the developing and remote areas of the world. Phytotherapy or therapeutics using plants and herb based compounds or crude drugs are an indispensable part of Complementary and Alternative Medicine (CAM. The benefits of most of these plants are controversial as their toxicology and pharmacological activities are not well studied and documented. However certain plants species like Ginko biloba and Crataegus have shown promise in experimental and clinical trials. In the present review, some anthropo-geographical and historical perspectives of phytotherapy are mentioned. Some important manifestations of cardiovascular pathology and their phytotherapy are reviewed. The holistic approach of phytotherapy and folkloric ethno medical practices indeed have opened new horizons for quality care in cardiovascular diseases. Phytotherapy and traditional medicine have proven their potential place in the modern and more skeptical evidence based medicine.

  7. Radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    The goal of this Chapter is to give a general outline of the essential principles and procedures for radiation protection in a nuclear medicine department where radionuclides are used for diagnosis and therapy. More detailed recommendations regarding radiation protection in nuclear medicine are given in the publications of the International Commission on Radiation Protection (ICRP, publications 25, 57, 60) and in ILO/IAEA/WHO Manual on Radiation Protection in Hospitals and General Practice (Volume 2: Unsealed Sources, WHO, Geneva, 1975), on which this Chapter is based. This chapter is not intended to replace the above-mentioned international recommendations on radiation protection, as well as existing national regulations on this subject, but intended only to provide guidance for implementing these recommendations in clinical practice

  8. Asian School of Nuclear Medicine

    International Nuclear Information System (INIS)

    The Asian School of Nuclear Medicine (ASNM) was formed in February 2003, with the ARCCNM as the parent body. Aims of ASNM: 1. To foster Education in Nuclear Medicine among the Asian countries, particularly the less developed ones. 2. To promote training of Nuclear Medicine Physicians in cooperation with government agencies, IAEA and universities and societies. 3. To assist in national and regional training courses, award continuing medical education (CME) points and provide regional experts for advanced educational programmes. 4. To work towards awarding of diplomas or degrees in association with recognized universities by distance learning and practical attachments, with examinations. The ASNM works toward a formal training courses leading to the award of a certificate in the long term. The most fundamental job of the ASNM remains the transfer of knowledge from the more developed countries to the less developed ones in the Asian region. The ASNM could award credit hours to the participants of training courses conducted in the various countries and conduct electronic courses and examinations. CME programmes may also be conducted as part of the regular ARCCNM meetings and the ASNM will award CME credit points for such activities

  9. Positron in nuclear medicine imaging

    International Nuclear Information System (INIS)

    The last two decades have witnessed a rapid expansion of clinical indications of positron emission tomography (PET) based imaging in assessing a wide range of disorders influencing their clinical management. This is primarily based upon a large dataset of evidence that has been generated over the years. The impact has been most remarkable in the field of cancer, where it takes a pivotal role in the decision making (at initial diagnosis, early response assessment and following completion of therapeutic intervention) of a number of important malignancies. The concept of PET based personalized cancer medicine is an evolving and attractive proposition that has gained significant momentum in recent years. The non-oncological applications of PET and PET/CT are in (A) Cardiovascular Diseases (e.g. Myocardial Viability, Flow reserve with PET Perfusion Imaging and atherosclerosis imaging); (B) Neuropsychiatric disorders (e.g. Dementia, Epileptic Focus detection, Parkinson's Disease, Hyperkinetic Movement Disorders and Psychiatric diseases); (C) Infection and Inflammatory Disorders (e.g. Pyrexia of Unknown origin, complicated Diabetic Foot, Periprosthetic Infection, Tuberculosis, Sarcoidosis, Vasculitic disorders etc). Apart from these, there are certain novel clinical applications where it is undergoing critical evaluation in various large and small scale studies across several centres across the world. The modality represents a classical example of a successful translational research of recent times with a revolutionary and far-reaching impact in the field of medicine. (author)

  10. Teaching of nuclear medicine at medical faculties

    International Nuclear Information System (INIS)

    The teaching of nuclear medicine at medical faculties in the CSSR is analyzed. It is shown that the teaching conditions are different at the individual faculties of medicine and the respective conditions are exemplified. (author). 4 tabs

  11. Quality assurance in nuclear medicine

    International Nuclear Information System (INIS)

    Most of the procedures in nuclear medicine deal with generation of functional images of various organs. By using appropriate software programmes various parameters of organ functions are derived. Due to automation and software refinements quality control of instrumentation has greatly improved. By introducing a QA programme significant improvement of image quality can be achieved. The percentage of retake of films can be drastically reduced. The financial gain can be substantial yielding to cost effectiveness of procedures. Continuous monitoring backed by effective communication and feedback from patients, referring physicians and payers of health care is essential to maintain a viable and responsive QA programme

  12. Nuclear medicine in district general hospitals.

    OpenAIRE

    Staffurth, J. S.

    1983-01-01

    Nuclear medicine is a recognised clinical specialty both nationally and internationally. Compared with other countries, it is inadequately developed in Britain, particularly in district general hospitals. To create clinical radioisotope services at district level physicians or radiologists with experience in nuclear medicine need to be trained and appointed. Such appointments would allow facilities to evolve that would provide either a comprehensive nuclear medicine service formed around a ph...

  13. Nuclear medicine applications for the diabetic foot

    Energy Technology Data Exchange (ETDEWEB)

    Hartshorne, M.F.; Peters, V.

    1987-04-01

    Although not frequently described in the podiatric literature, nuclear medicine imaging may be of great assistance to the clinical podiatrist. This report reviews in detail the use of modern nuclear medicine approaches to the diagnosis and management of the diabetic foot. Nuclear medicine techniques are helpful in evaluating possible osteomyelitis, in determining appropriate amputation levels, and in predicting response to conservative ulcer management. Specific indications for bone, gallium, and perfusion imaging are described.

  14. Nuclear Medicine Imaging in Pediatric Neurology

    OpenAIRE

    Ümit Özgür Akdemir; Lütfiye Özlem; Atay Kapucu

    2016-01-01

    Nuclear medicine imaging can provide important complementary information in the management of pediatric patients with neurological diseases. Pre-surgical localization of the epileptogenic focus in medically refractory epilepsy patients is the most common indication for nuclear medicine imaging in pediatric neurology. In patients with temporal lobe epilepsy, nuclear medicine imaging is particularly useful when magnetic resonance imaging findings are normal or its findings are discordant with e...

  15. Dementia and rural nuclear medicine

    International Nuclear Information System (INIS)

    Full text: The rapid increase in dementia is directly related to the growing number of aged people in developed countries, such as Australia. This increase heightens the need for accurate dementia diagnosis to ensure treatment resources are appropriately allocated. However, current diagnostic methods are unable to determine specific dementia types limiting the effectiveness of many care plans. The lack of specialist resources in rural Australian communities presents nuclear medicine with an opportunity to make a significant impact on the management of this disease. This investigation aimed to identify how SPECT perfusion imaging could maximise its role in the management of dementia in a rural New South Wales setting. The study reviewed all Technetium 99m HMPAO SPECT brain studies over a three-year period. This included a medical record audit, review of all diagnostic imaging reports and an analysis of referral patterns. The results of this study provide compelling evidence that, even in a rural setting, brain SPECT, in conjunction with neuropsychological testing, offers high accuracy in determining the presence and type of dementia. In addition, the study found more than 30% of referrers had no training in SPECT, emphasising the importance of ensuring that brain SPECT reports, in a rural setting, educate and specify to referrers the significance and exact disease type found in the study. Copyright (2003) The Australian and New Zealand Society of Nuclear Medicine Inc

  16. Pulmonary applications of nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine techniques have a long history in pulmonary medicine, one that has been continually changing and growing. Even longstanding methods, such as perfusion scanning for embolic disease or for pretherapy pulmonary function evaluation, have largely withstood the test of recent careful scrutiny. Not only have these techniques remained an important part of the diagnostic armamentarium, but we have learned how to use them more effectively. Furthermore, because of technical advances, we are in a phase of expanding roles for nuclear imaging. Gallium citrate scanning for the mediastinal staging and follow-up of lymphoma has been recognized as a valuable adjunct to the anatomic information provided by CT and MRI. With the growth of PET technology in areas that have been explored in a limited fashion until now, such as noncardiogenic pulmonary edema and lung carcinoma, evaluation and management of these patients may substantially improve. Finally, in the field of radiolabeled monoclonal antibodies, attention is now being turned to both the diagnostic and the therapeutic problems presented by lung carcinoma. As radiolabeling methods are refined and as new and better antibodies are developed, radioimmunodetection and therapy in lung carcinoma may begin to make inroads on this common and hard to control disease.157 references

  17. Equipment used in nuclear medicine

    International Nuclear Information System (INIS)

    Detection of radiation is the common purpose of all equipment's and instruments used in radioisotope laboratories. The first and most important instrument that was used in nuclear medicine was Geiger tube developed by H.W. Geiger as early in 1908. He in association with Mueller developed the so called Geiger-Muller tube (GM tube) which could be used to detect beta and gamma radiations. In spite of its severe limitations, GM tube remained the only external counting device until 1949. In 1948, Kallman reported that the scintillations can be detected and amplified with the help of photomultiplier tubes (PMTs). In comparison with gas filled detectors, scintillation detectors have two principal advantages that augment their use in nuclear medicine. Firstly, they are capable of much higher counting rates because of fast resolving times and secondly, because they are much more efficient for gamma ray detection. The scintillation detector is the most basic block of any modern radioisotope detection instrument like rate meter, counter, scanner, gamma camera or single photon emission computed tomography. (author)

  18. Nuclear medicine applications in AIDS

    International Nuclear Information System (INIS)

    Full text: Aids patients are liable to more than one medical problem at anyone time as the number of CD4 cells decrease and the viral load increases. Problems are related to multiple causes of opportunistic Infections, malignant lymphoma and Kaposi sarcoma. Laboratory tests, sputum analysis and bronchial lavage have problems of decreased sensitivity. morphologic Imaging modalities such as chest X-ray, CT or MRI has problems of specificity. Nuclear medicine techniques has the advantage of total body functional imaging that can visualize more than one organ. The use nuclear medicine imaging is recommended when the diagnosis is uncertain and for initiation of proper treatment. Gallium-67 citrate total body scans acquired at 4 hours following the IV injection and at 24-48 hours has been very useful for the early diagnosis of opportunistic infections such as PCP, TB, Disseminated Mycobacterium avii complex; MAI, malignant lymphoma and various forms of AIDS related colitis. Sequential thallium and gallium scan help to differentiate Kaposi sarcoma (thallium positive, gallium negative) from opportunistic infections (gallium positive, thallium negative) and malignant lymphoma (thallium and gallium positive). Gallium is the most convenient radiopharmaceutical for the diagnosis of malignant lymphoma of the heart. Thallium and Tc-99m Sestamibi are useful for the differentiation of intracranial toxoplasmosis from malignant lymphoma. The presentation will illustrate different examples and will explain the limitations of all these tests. (author)

  19. Infection diagnosis in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Martin-Comin, J. [Hospital Princeps d`Espanya, Barcelona (Spain). Servicio de Medicina Nuclear

    1997-12-31

    Full text. The clinical applicability of agents like 67 Ga and 111 In-labelled leukocytes began the era of infection imaging diagnosis in Nuclear Medicine, more than two decades ago. In this period other agents have appeared in the field. 99 m Tc-HMPAQ-leukocytes and 99 m Tc-anti granulocyte monoclonal antibodies (able to label white blood cells) and 111 In and 99 mTc-polyclonal immuno globulins (in cold kit presentation). These agents had widespread the use of Nuclear Medicine procedures in clinical practice. Nevertheless, there is not, up to now, an specific agent to diagnose infection and is some cases a second or third agent (i.e.: 99 mTc-colloid) is used to obtain an accurate diagnosis. Actually, research is orientated to the development of agents with low antigenic power (peptides or fragments of monoclonal antibodies), or other non immunogenic agents involved in the inflammation process (selectin, antibiotic). Some experiences have also been done with PET agents. The clinical usefulness of commercially available agents and the future possibilities of the new ones will be presented

  20. ICRP 60 and nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Galli, G. (Rome Univ. Cattolica del S. Cuore (Italy). Ist. di Medicina Nucleare)

    For that which regards the field of nuclear medicine, the new International Commission on Radiation Protection recommendations (ICRP 60) are highly innovative in that the differentiation between 'controlled' and ' monitored' areas is no longer tied to fractions of annual dose limits, but it is instead established locally on the basis of operational experience and judgement. The most notable feature of the new recommendations, however, concerns the new 20 mSv dose limit for exposed workers, the 1 mSv limit for the public (understood as the 5 year annual average), as well as, the modifications to the annual limits on the intake of radionuclides, e.g., inhalation of I 131 passes from 2*10/sup 6/ to 1*10/sup 6/. This paper assesses the impacts of these new limits on the performance of ' in vivo' medical diagnostics and radio-metabolic therapy with unsealed sources. Attention is given to possible negative consequences on the implementation of nuclear medicine due to the current trend towards lower limits, and to the implications of the new recommendations as regards medical support staff and family members of individuals undergoing radiotherapy.

  1. Radiosanitary control in nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear Medicine has recently modified radiosanitary control standards for the three sectors involved: patients, personnel and general population. Nuclear Medicine does not constitute an important source of radiation, including patients and population, compared with radiology. The basic problems of radiosanitary controls are: the absorbed dose and the patient. Low risk deferred stochastic effects may appear with correct use of these controls. On the other hand, risk of stochastic consequences and non stochastic complications appear with incorrect applications. The following aspects should be considered for correct uses: A-1- The critical organ, which is not always the one under study. 2-The rest of the organism, specially the more sensitive organs. B- The radiopharmaceutical used, considering the following periods: physical, biological and effective. C-Technical and human resources that include quality control for the equipment. Radiosanitary control aims at a common objetive: dose limitation to the patient, personnel and general population. For this, it is necessary to accomplish the training programme for proffesional and technical personnel about quality control and to stablish basic standards for the equipment. Current law and regulations assign to the National Atomic Energy Comission the responsibility for controlling the use of radioisotopes and radiations in order to safeguard the health and life of the population. (M.E.L.)

  2. Nuclear medicine - the condition and prospects

    International Nuclear Information System (INIS)

    Full text: The nuclear medicine has rather strongly determined the place in clinical and diagnostic practice. Statistical researches show, that, even despite of the certain successes in treatment of many diseases, rather high death rate at cardiovascular, oncological and many other diseases. The urgency of clinical tasks connected with a state of health of the population puts before nuclear medicine a (task) on development and introduction of new methods of diagnostics and therapy. The nuclear medicine is characterized by some number of diagnostic and therapeutic methods which application frequently does not have other alternative. The methods of visualization used in nuclear medicine, are full informative, exact and have ability to reveal structurally functional changes of bodies and fabrics practically at a cellular level. To present time diagnostic radiopharmacy (Ph) wed practically in all clinical areas of medicine. In world practice steady growth of increase of manufacture as diagnostic and radiotherapeutic RP was planned. The even greater (reduction) of potential risk one and of conditions by which development of nuclear medicine in the near future is defined is at realization of the procedures connected to application of radioactive preparations and reduction of beam loadings on the patient. An important point in the clinic-diagnostic field is replacement the RP on short-lived and ultra short-lived. Among examples of such transition it is necessary to name replacement 131I in diagnostic application on 123I, and also active introduction PET. It is possible to call essentially new direction of development of technologies of the directed transport the open radioactive isotopes and RP to pathology changed bodies or organisms demanding realization of diagnostic procedures or selective beam therapy. However, despite of huge potential opportunities of the domestic nuclear industry, even such old method as the radiotherapy I-131 - is used by iodine in our country in

  3. Special monitoring in nuclear medicine

    International Nuclear Information System (INIS)

    Colombia counts with around 56 centers of Nuclear Medicine, 70 Nuclear Doctors and more of 100 Technologists in this area. The radioisotopes more used are the 131 I and the 99m Tc. The radiological surveillance singular in the country is carried out for external dosimetry, being the surveillance by incorporation of radioactive materials very sporadic in our media. Given the necessity to implement monitoring programs in the incorporation of radionuclides of the occupationally exposed personnel, in the routine practice them routine of Nuclear Medicine, it was implemented a pilot program of Special Monitoring with two centers of importance in the city of Medellin. This program it was carried out with the purpose of educating, to stimulate and to establish a program of reference monitoring with base in the National Program of Monitoring in the radionuclides Incorporation that serves like base for its application at level of all the services of Nuclear Medicine in the country. This monitoring type was carried out with the purpose of obtaining information on the work routine in these centers, form of manipulation and dosage of the radionuclides, as well as the administration to the patient. The application of the program was carried out to define the frequency of Monitoring and analysis technique for the implementation of a program of routine monitoring, following the recommendations of the International Commission of Radiological Protection. For their application methods of activity evaluation were used in urine and in 7 workers thyroid, of those which only two deserve an analysis because they presented important activities. The measures were carried out during one month, every day by means in urine samples and to the most critic case is practiced two thyroid measures, one in the middle of the period and another when concluding the monitoring. To the other guy is practiced an activity count in thyroid when concluding the monitoring period. The obtained result of the

  4. Quality Management in Nuclear Medicine

    International Nuclear Information System (INIS)

    The IAEA has strong Nuclear medicine (NM) programs and the international basic safety standards require that radiation medicine centers establish a comprehensive quality assurance program for medical exposures supported by internal and external audits. Vital for this is the development of all-inclusive IAEA guideline on 'Quality management in Nuclear Medicine' (also referred to as 'QUANUM'). This document consists of 50 pages and each chapter is set out as a series of questions related to a specific component of NM service. It takes into account the diversity of NM practices and the multidisciplinary contributions (i.e. clinical, physics, radiopharmacy). Self appraisal, external audit and continuous improvement are central elements to improving QA in NM practice. The foremost intention of this document is to introduce a culture of annual systematic review processes into the clinical arena. External audit starts with a formal request together with a completed self appraisal. Each IAEA region will have a pool of trained auditors from each NM discipline. The auditing team will be fully aware of the background and practices by interrogation of NUMDAB (NM database) and recent self appraisal. Normally a 3 day external audit starts with a briefing meeting and ends with a debriefing on the finalization of the audit report. During the external audit, a standardized approach is followed which includes service orientation, introduction to key individuals and access to essential data. The audit team will follow representative clinical cases from clinical requests, clinical direction, patient preparation, radiopharmaceutical dispensing, individual scanning, data processing, report and follow-up of the report. In a few cases, discussions with individual referring physicians will establish patient outcome together with the impact of the NM service. The standards of practice will be compared to national, regional or international guidelines (i.e. IAEA Nuclear medicine resources

  5. Cardiovascular nuclear medicine in infancy and childhood

    International Nuclear Information System (INIS)

    Radionuclide angiocardiography and lung scanning in the diagnosis of congenital heart disease in infants and children are introduced and discussed. Recently developed radionuclide angiocardiography is a safe and useful method in the detection and quantification of intracardiac shunts, together with for the measurement of transit times, left ventricular ejection fraction and cardiac output. Lung scanning is useful in the evaluation of pulmonary blood flow distribution in the congenital heart disease such as ventricular septal defect (VSD), tetralogy of Fallot (TOF), etc. To decide the limitation of operative indication for VSD with severe pulmonary hypertension, the ratio of pulmonary blood flow distribution in upper to lower lung filed above 1.2, the right to left shunt ratio above 0.25, and deranged blood flow distribution on bilateral lungs are useful as the criteria. In the follow up study after intracardiac repair of TOF, lung scanning reflects the residua and sequalae such as pulmonary stenosis, pulmonary insufficiency, pulmonary hypertension, peripheral pulmonary stenosis and anomalous dilatation of the right ventricular outflow tract. (author)

  6. Sex/Gender Medicine: The Biological Basis for Personalized Care in Cardiovascular Medicine

    OpenAIRE

    Arain, Faisal A.; Kuniyoshi, Fatima H.; Abdalrhim, Ahmed D.; Miller, Virginia M

    2009-01-01

    Sex differences in morbidity and mortality associated with cardiovascular disease have been recognized by the medical com006Dunity for decades. Investigation into the underlying biological basis of these differences was largely neglected by the scientific community until a report released by the Institute of Medicine in the United States in 2001 “Exploring the Biological Contributions to Human Health: Does Sex Matter?” Recommendations from this report included the need for more accurate use o...

  7. Optimisation of protection in nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine is a branch of clinical medicine, which is concerned mainly with the use of unsealed sources of radionuclides for various diagnostic and therapeutic applications. The purpose of this paper is to acquaint with the essential principles and procedures of radiation protection, so that nuclear medicine procedures are performed in a manner by which the radiation exposure to the patient, staff and public are kept as low as reasonably achievable (ALARA). The philosophy of radiation protection in nuclear medicine involves protection of the patient, of the staff and the public

  8. Links between nuclear medicine and radiopharmacy

    International Nuclear Information System (INIS)

    Radiopharmaceuticals are nowadays under the responsibility of the radio-pharmacist because of their medicinal product status. Radiopharmacy belongs to the hospital pharmacy department, nevertheless, interactions with nuclear medicine department are important: rooms are included or located near nuclear medicine departments in order to respect radiation protection rules, more over staff, a part of the material and some activities are shared between the two departments. Consequently, it seems essential to formalize links between the radiopharmacy and the nuclear medicine department, setting the goals to avoid conflicts and to ensure patients' security. Modalities chosen for this formalization will depend on the establishment's organization. (authors)

  9. Nuclear Medicine Technology: A Suggested Postsecondary Curriculum.

    Science.gov (United States)

    Technical Education Research Center, Cambridge, MA.

    The purpose of this curriculum guide is to assist administrators and instructors in establishing nuclear medicine technician programs that will meet the accreditation standards of the American Medical Association (AMA) Council on Medical Education. The guide has been developed to prepare nuclear medicine technicians (NMT's) in two-year…

  10. Radionuclides for nuclear medicine: a nuclear physicists' view

    Czech Academy of Sciences Publication Activity Database

    Cantone, M.; Haddad, F.; Harissopoulos, S.; Jensen, M.; Jokinen, A.; Koster, U.; Lebeda, Ondřej; Ponsard, B.; Ratzinger, U.; Stora, T.; Tarkanyi, F.; Van Duppen, P.

    2013-01-01

    Roč. 40, 2 Supplement (2013), S257-S257. ISSN 1619-7070. [Annual Congress of the European Association of Nuclear Medicine (EANM). 19.10.2013-23.10.2013, Lyon] Institutional support: RVO:61389005 Keywords : nuclear physics for medicine * EANM * medical radionuclides Subject RIV: BG - Nuclear , Atomic and Molecular Physics, Colliders

  11. Growth of Nuclear Medicine in India

    Directory of Open Access Journals (Sweden)

    A.M. Samuel

    1990-10-01

    Full Text Available The growth of nuclear medicine in India is linked with the developments in our Atomic Energy Programme. Self-sufficiency in radiopharmaceuticals for both in vivo and in vitro use has been largely achieved. The availability of instrumentation facilities in over 90 nuclear medicine centres is indicated. The activities of the Radiation Medicine Centre, a pioneer institute, in the field of diagnosis, therapy and training of personnel are summarised.

  12. Course on internal dosimetry in nuclear medicine

    International Nuclear Information System (INIS)

    This documentation was distributed to the participants in the Course of Internal Dosimetry in Nuclear Medicine organised by the Nuclear Regulatory Authority (ARN) of Argentina and held in Buenos Aires, Argentina, August 9-13, 2004. The course was intended for people from IAEA Member States in the Latin American and Caribbean region, and for professionals and workers in medicine, related with the radiation protection. Spanish and English were the languages of the course. The following subjects were covered: radioprotection of the patient in nuclear medicine; injuries by ionizing radiations; MIRD methodology; radiation dose assessment in nuclear medicine; small scale and microdosimetry; bone and marrow dose modelling; medical internal dose calculations; SPECT and image reconstruction; principles of the gamma camera; scattering and attenuation correction in SPECT; tomography in nuclear medicine

  13. Progress in renal nuclear medicine

    International Nuclear Information System (INIS)

    Progress in nuclear nephrology has come through an understanding of two specific pharmacological interventions: Frusemide and Captopril. Obstruction to outflow may be defined as an increased resistance to outflow above normal. This is usually associated with dilatation of the outflow tract. The obstructing uropathy cannot usually be distinguished from a dilated baggy unobstructive pelvis by examination of the renal images nor the renal activity time curve. In this situation a diuretic renography test with frusemid and calculation of outflow efficiency is very helpful. Captopril intervention was introduced as a form of stress test for the kidney and is able to improve the specificity of the distinction between Essential and Renovascular Hypertension. The typical features therefore are a delayed peak to the renogram, an impaired second phase, a series of images showing a delay in the time for activity to appear in the pelvis, and a prolongation of the mean parenchymal transit time. A study is also a good predictor of the presence of functionally significant restenosis if the patient is followed serially. In conclusion, intervention in renal nuclear medicine is becoming part of standard practice. The substitution of time based measurements for count based measurements should be the trend for the future. (author)

  14. Mechanisms in Cardiovascular Diseases: How Useful Are Medical Textbooks, eMedicine, and YouTube?

    Science.gov (United States)

    Azer, Samy A.

    2014-01-01

    The aim of this study was to assess the contents of medical textbooks, eMedicine (Medscape) topics, and YouTube videos on cardiovascular mechanisms. Medical textbooks, eMedicine articles, and YouTube were searched for cardiovascular mechanisms. Using appraisal forms, copies of these resources and videos were evaluated independently by three…

  15. Experience with Nuclear Medicine Information System

    Directory of Open Access Journals (Sweden)

    Bilge Volkan-Salanci

    2012-12-01

    Full Text Available Objective: Radiology information system (RIS is basically evolved for the need of radiologists and ignores the vital steps needed for a proper work flow of Nuclear Medicine Department. Moreover, CT/MRI oriented classical PACS systems are far from satisfying Nuclear Physicians like storing dynamic data for reprocessing and quantitative analysis of colored images. Our purpose was to develop a workflow based Nuclear Medicine Information System (NMIS that fulfills the needs of Nuclear Medicine Department and its integration to hospital PACS system. Material and Methods: Workflow in NMIS uses HL7 (health level seven and steps include, patient scheduling and retrieving information from HIS (hospital information system, radiopharmacy, acquisition, digital reporting and approval of the reports using Nuclear Medicine specific diagnostic codes. Images and dynamic data from cameras of are sent to and retrieved from PACS system (Corttex© for reprocessing and quantitative analysis. Results: NMIS has additional functions to the RIS such as radiopharmaceutical management program which includes stock recording of both radioactive and non-radioactive substances, calculation of the radiopharmaceutical dose for individual patient according to body weight and maximum permissible activity, and calculation of radioactivity left per unit volume for each radionuclide according their half lives. Patient scheduling and gamma camera patient work list settings were arranged according to specific Nuclear Medicine procedures. Nuclear Medicine images and reports can be retrieved and viewed from HIS. Conclusion: NMIS provides functionality to standard RIS and PACS system according to the needs of Nuclear Medicine. (MIRT 2012;21:97-102

  16. E-learning for Nuclear Medicine

    International Nuclear Information System (INIS)

    The E-Learning in Nuclear Medicine was developed by the Asian School of Nuclear Medicine (ASNM) through the TC regional project, RAS/0/047 to respond to the need for continuing education of physicians, technologists and other allied professionals working in Nuclear Medicine. ASNM is the collaborating member of the Asian Network for Education in Nuclear Technology (ANENT) and is involved in some educational activities of the IAEA. Ten various cases on different types of organ-system were collected from nine member countries (Bangladesh, India, Indonesia, Japan, Republic of Korea, Malaysia, Pakistan, the Philippines, and Thailand). About 100 cases covered the following organ-systems: Oncology, Cardiology, Neurology, Gastroenterology/Hepatobiliary, Pulmonary, Endocrinology, Pediatrics, Nephrology/Urology, Infection, Muskulo-skeletal, Ophthalmology. Radiotherapy, dosimetry and nuclear medicine diagnostic techniques including PET and SPECT as well as labelling of tracer and application of radiopharmals are covered in the training modules

  17. Maintenance of nuclear medicine instruments

    International Nuclear Information System (INIS)

    Maintenance of instruments is generally of two kinds: (a) corrective maintenance, on a non-scheduled basis, to restore equipment to a functional status by repairs; (b) preventive maintenance, to keep equipment in a specified functional condition by providing systematic inspection, quality control, detection and correction of early malfunctions. Most of the instruments used in nuclear medicine are rather complex systems built from mechanical, electrical and electronic parts. Any one of these components is liable to fail at some time or other. Repair could be done only by a specialist who is able to evaluate the condition of the various parts ranging from cables to connectors, from scintillators to photomultipliers, from microprocessors to microswitches. The knowledge of the intricacies of the various electronic components required for their repairs is quite wide and varied. The electronics industry turns out more and more multi-purpose chips which can carry out the functions of many parts used in the instruments of the earlier generation. This provides protection against unauthorized copying of the circuits but it serves another purpose as well of inhibiting repairs by non-factory personnel. These trends of the instrument design should be taken into consideration when a policy has to be developed for the repairs of the hospital based equipment

  18. Quality control of nuclear medicine instruments, 1991

    International Nuclear Information System (INIS)

    This document gives detailed guidance on the quality control of various instruments used in nuclear medicine. A first preliminary document was drawn up in 1979. A revised and extended version, incorporating recommended procedures, test schedules and protocols was prepared in 1982. The first edition of 'Quality Control of Nuclear Medicine Instruments', IAEA-TECDOC-317, was printed in late 1984. Recent advances in the field of nuclear medicine imaging made it necessary to add a chapter on Camera-Computer Systems and another on SPECT Systems

  19. Quality control of nuclear medicine instruments 1991

    International Nuclear Information System (INIS)

    This document gives detailed guidance on the quality control of various instruments used in nuclear medicine. A first preliminary document was drawn up in 1979. A revised and extended version, incorporating recommended procedures, test schedules and protocols was prepared in 1982. The first edition of ''Quality Control of Nuclear Medicine Instruments'', IAEA-TECDOC-317, was printed in late 1984. Recent advances in the field of nuclear medicine imaging made it necessary to add a chapter on Camera-Computer Systems and another on SPECT Systems. Figs and tabs

  20. Physics and radiobiology of nuclear medicine

    CERN Document Server

    Saha, Gopal B

    2010-01-01

    From a distinguished author comes this new edition for technologists, practitioners, residents, and students in radiology and nuclear medicine. Encompassing major topics in nuclear medicine from the basic physics of radioactive decay to instrumentation and radiobiology, it is an ideal review for Board and Registry examinations. The material is well organized and written with clarity. The book is supplemented with tables and illustrations throughout. It provides a quick reference book that is concise but comprehensive, and offers a complete discussion of topics for the nuclear medicine and radi

  1. Systems and signal processing in nuclear medicine

    International Nuclear Information System (INIS)

    Proceedings covering all lectures presented to the 7th Spring Meeting of Deutsche Gesellschaft fuer Med. Dokumentation, Informatik und Statistik, GMDS, on the subject of ''Systems and signal processing in nuclear medicine''. Currently available systems for nuclear medicine and their application in administration, documentation and clinical routine examinations are dealt with in the first part. Three papers discuss various methods of signal processing, and methods of automatic image processing are dealt with at length. Trends of development are discussed, and the situation of nuclear medicine in various European countries is reviewed. (WU)

  2. Past, current and future aspects of nuclear medicine in Malaysia

    International Nuclear Information System (INIS)

    Nuclear Medicine in Malaysia began initially with the use of radioiodine and radiophosphorous for the investigation and treatment of thyroid and blood disorders around 1960. Following this we went through a phase of organ imaging using radioiodine and radiogold using an early generation Phillips Scanner. In terms of Medical usefulness this proved a big step forward in Malaysian Medicine, basic though the techniques were. The third phase of this speciality came on in the 1970s with the availability of generator scanners. A tremendous spurt in Nuclear Imaging and thyroid function studies took place. We have now together with the University Hospital Gamma Cameras which have considerably widened the scope of Nuclear Medicine especially in the field of cardiovascular studies. Further advances are expected in the future with the availability of medical cyclotrons, positron cameras and emission tomography. However yesterdays problems have not disappeared completely and the training of personnel and provision of up to date Nuclear Medicine laboratories with the latest equipment should be given top priority so as to assure progress in this speciality. (author)

  3. Nuclear medicine applications: Summary of Panel 4

    Energy Technology Data Exchange (ETDEWEB)

    Wolf, A.P.

    1988-01-01

    Nuclear medicine is currently facing a desperate shortage of organic and inorganic chemists and nuclear pharmacists who also have advanced training in nuclear and radiochemistry. Ironically, this shortfall is occurring in the face of rapid growth and technological advances which have made the practice of nuclear medicine an integral part of the modern health care system. This shortage threatens to limit the availability of radiopharmaceuticals required in routine hospital procedures and to impede the development of new diagnostic and therapeutic agents. To redress this need and prevent a similar shortfall in the future, this panel recommends immediate action and a long-term commitment to the following: educating the public on the benefits of nuclear medicine; informing undergraduate and graduate chemistry students about career opportunities in nuclear medicine; offering upper level courses in nuclear and radiochemistry (including laboratory) in universities; establishing training centers and fellowships at the postgraduate level for specialized education in the aspects of nuclear and radiochemistry required by the nuclear medicine profession. 1 tab.

  4. Nuclear medicine applications: Summary of Panel 4

    International Nuclear Information System (INIS)

    Nuclear medicine is currently facing a desperate shortage of organic and inorganic chemists and nuclear pharmacists who also have advanced training in nuclear and radiochemistry. Ironically, this shortfall is occurring in the face of rapid growth and technological advances which have made the practice of nuclear medicine an integral part of the modern health care system. This shortage threatens to limit the availability of radiopharmaceuticals required in routine hospital procedures and to impede the development of new diagnostic and therapeutic agents. To redress this need and prevent a similar shortfall in the future, this panel recommends immediate action and a long-term commitment to the following: educating the public on the benefits of nuclear medicine; informing undergraduate and graduate chemistry students about career opportunities in nuclear medicine; offering upper level courses in nuclear and radiochemistry (including laboratory) in universities; establishing training centers and fellowships at the postgraduate level for specialized education in the aspects of nuclear and radiochemistry required by the nuclear medicine profession. 1 tab

  5. Development of nuclear medicine in Mongolia

    International Nuclear Information System (INIS)

    Full text: Progress during the past quarter of a century in the development and medical uses of radioisotopes and radiopharmaceuticals, and the benefits derived from their applications have been outstanding. The World health Organization (WHO) has stated that 'Nuclear Medicine' is taken to embrace all applications of radioactive materials in diagnosis, treatment or in medical research, with the exception of the use of sealed radiation sources in radiotherapy. How did the term come into use? In 1951 the editorial board of the American Journal of Roentgenology and Radium therapy decided to express its special interest in the field by a change in the title of that journal. The words 'and Nuclear Medicine' were added. Nuclear medicine was first introduced in Mongolia in the year 1975; 31 March 1975 to be precise, when radioiodine uptake studies and radio isotope renogram were first introduced in the country. Simultaneously several other studies like liver scanning with Au-198 Sulfur colloid and Pancreas imaging with Se-75 methionine were also introduced using the newly installed single and dual probe scintillation detector system and the Hungarian rectilinear scanner. Prof. Dr. Peljee Onkhuudai, presently the head of nuclear medicine at the First State Central Hospital, was the prime mover of these initiatives. He was the first physician from Mongolia to be fully qualified in Nuclear Medicine in the year 1975. He had his education and training in nuclear medicine at the Karl-Marx-University, Leipzig in Germany. In the year 1982 Mongolia received its first gamma camera (a new Siemens Gamma camera-PHO-ZLC) as well as started its RIA facility through an IAEA Technical Cooperation Project. Hence from the year 1982 the Nuclear Medicine Department has been responsible for providing both in vivo and in vitro nuclear medicine services to the people of Mongolia including Radionuclide therapy. There has been a gradual expansion of the department with respect to personnel

  6. Hand Dose in Nuclear Medicine Staff Members

    International Nuclear Information System (INIS)

    Measurement of the hand dose during preparation and injection of radiopharmaceuticals is useful in the assessment of the extremity doses received by nuclear medicine personnel. Hand radiation doses to the occupational workers that handling 99mTc-labeled compounds, 131I for diagnostic in nuclear medicine were measured by thermoluminescence dosimetry. A convenient method is to use a TLD ring dosimeter for measuring doses of the diagnostic units of different nuclear medicine facilities . Their doses were reported in millisieverts that accumulated in 4 weeks. The radiation doses to the hands of nuclear medicine staff at the hospitals under study were measured. The maximum expected annual dose to the extremities appeared to be less than the annual limit (500 mSv/y) because all of these workers are on rotation and do not constantly handle radioactivity throughout the year

  7. Development of PACS in nuclear medicine

    International Nuclear Information System (INIS)

    The in-house development of Picture Archiving and Communication System (PACS) in Nuclear Medicine is cost-effective. It provides various expansion options in transfer, processing, archival and retrieval of images according to the convenience of the department

  8. Highlights of the annual meeting of the European Association of Nuclear Medicine: Glasgow 1997. The Flowering of Science and Art of Nuclear Medicine in Europe

    International Nuclear Information System (INIS)

    This year, 18% of the abstracts were in the field of oncology, 16% in cardiovascular nuclear medicine, 12% in neurology and psychiatry, 11% in chemistry and tracers, 12% in physics and instrumentation, 7% in therapy and the remaining 24% in many other equally important fields. (orig./MG)

  9. A DICOM based PACS for nuclear medicine

    International Nuclear Information System (INIS)

    The installation of a radiology information system (RIS) connected to a hospital information system (HIS) and a picture archiving and communications system (PACS) seems mandatory for a nuclear medicine department in order to guarantee a high patient throughput. With these systems a fast transmission of reports, images to the in- and out-patients' wards and private practitioners is realized. Therefore, since April 2000, at the department of nuclear medicine of the university of Wuerzburg a completely DICOM based PACS has been implemented in addition to the RIS. With this system a DICOM based workflow is realized throughout the department of nuclear medicine for reporting and archiving. The PACS is connected to six gamma-cameras, a PET scanner, a bone densitometry system and an ultrasound device. The volume of image data archived per month is 4 GByte. Patient demographics are provided to the modalities via DICOM-Worklist. With these PACS components a department specific archive purely based on DICOM can be realized. During the installation process problems occurred mainly because of the complex DICOM standard for nuclear medicine. Related to that is the problem that most of the software implementations still contain bugs or are not adapted to the needs of a nuclear medicine department (particularly for PET). A communication software for the distribution of nuclear medicine reports and images based on techniques used for the worldwide web is currently tested. (orig.)

  10. What the future holds for nuclear medicine

    International Nuclear Information System (INIS)

    The American College of Nuclear Physicians is primarily interested in the practice aspects of the delivery of nuclear medicine patient care. Yet no specialty in medicine is as directly tied to its scientific base as we are. This International Symposium on Single-Photon Ultrashort-Lived Radionuclides is a classic example of this interdependence. The survival of nuclear medicine as a medical specialty is absolutely dependent on the development of high technology, and the transfer of that technology to medical practice, through the cooperative efforts of industry, government, practitioners, and the research community. If there is no nuclear practice, there will be little outlet for our scientific accomplishments. The American College of Nuclear Physicians therefore considers it to be one of its prime missions to highlight those areas on the leading edge of technology which are, or at least appear to be, ready to bring on-line routine clinical practice

  11. Nuclear medicine and how it developed

    International Nuclear Information System (INIS)

    Nuclear medicine is the science of using nuclear properties of matter in medicine. The elemental particles like protons and neutrons are in a particular arrangement or constellation to each other in the nucleus of an atom. If this constellation is disturbed by changing their numbers or position to each other in a cyclotron or a nuclear reactor, the nucleus of such an atom will try to come back to a stable constellation by giving up or emitting energy in form of radiations. This is the basic nuclear property of matter. This chapter also briefly discussed on the development of nuclear medicine since the discovery of radium by Madam Curie and utilization of radioisotopes for the study of plant physiology by George von Hevesy. (author)

  12. A Training Manual for Nuclear Medicine Technologists.

    Science.gov (United States)

    Simmons, Guy H.; Alexander, George W.

    This manual was prepared for a training program in Nuclear Medicine Technology at the University of Cincinnati. Instructional materials for students enrolled in these courses in the training program include: Nuclear Physics and Instrumentation, Radionuclide Measurements, Radiation Protection, and Tracer Methodology and Radiopharmaceuticals. (CS)

  13. VIIth international symposium on nuclear medicine

    International Nuclear Information System (INIS)

    The conference proceedings contain abstracts of 100 presented papers, mainly dealing with radioimmunoassays, radiopharmaceuticals, scintiscanning, computer tomography, radionuclide lymphography, ventriculography, angiography, nuclear cardiology, liquid scintillator techniques, radioisotope generators, radiospirometry and various uses of labelled compounds and tracer techniques in nuclear medicine. (M.D.)

  14. Nuclear medicine development in the southern urals

    International Nuclear Information System (INIS)

    The last 25 years results of organization work at Nuclear Medicine cluster in the Southern Urals are presented. The main purpose of the project was - to create one of the largest Russian platforms for the development and application of nuclear technology. A successive branched system of radiopharmaceutical production and radiopharmaceuticals consumers effectively operate in the region, and is provided by prepared staff and is able to provide high-tech care for cancer patients using nuclear program in the field of health care

  15. Quality management audits in nuclear medicine practices

    International Nuclear Information System (INIS)

    An effective management system that integrates quality management (QM) is essential in modern nuclear medicine departments in Member States. The IAEA, in its Safety Standards Series, has published a Safety Requirement (GS-R-3) and a Safety Guide (GS-G-3.1) on management systems for all facilities. These publications address the application of an integrated management system approach that is applicable to nuclear medicine organizations as well. Quality management systems are maintained with the intent to continuously improve effectiveness and efficiency, enabling nuclear medicine to achieve the expectations of its quality policy, and to satisfy its customers. The IAEA has a long history of providing assistance in the field of nuclear medicine to its Member States. Regular quality audits and assessments are essential for modern nuclear medicine departments. More importantly, the entire QM and audit process has to be systematic, patient oriented and outcome based. The management of services should also take into account the diversity of nuclear medicine services around the world and multidisciplinary contributions. The latter include clinical, technical, radiopharmaceutical and medical physics procedures. Aspects of radiation safety and patient protection should also be integral to the process. Such an approach ensures consistency in providing safe, quality and superior services to patients. Increasingly standardized clinical protocol and evidence based medicine is used in nuclear medicine services, and some of these are recommended in numerous IAEA publications, for example, the Nuclear Medicine Resources Manual. Reference should also be made to other IAEA publications such as the IAEA Safety Standards Series, which include the regulations for the safe transport of nuclear material and on waste management as all of these have an impact on the provision of nuclear medicine services. The main objective of this publication is to introduce a routine of conducting an

  16. Nuclear medicine - from physiology to molecular imaging

    International Nuclear Information System (INIS)

    The induction of Medical Imaging in clinical practice occurred through Nuclear Medicine in 1937 through the first application of 131-Iodine in tracer imaging. The concept translated rapidly into other areas of clinical medicine through the invention of newer radiopharmaceuticals over the next six decades. The growth of nuclear imaging acted as a catalyst for other imaging modalities like sonography, CT scan and MRI. In effect everywhere nuclear medicine was the stimulus and growth has taken place around its concepts. This in turn strengthened and stimulated further fascinating developments in nuclear medicine so much that today it is the fascinating era of 'FUSION IMAGING' in medical diagnosis. The CT and MRI succeeded in producing exquisite images of human organs with details as close to as a pathologist would see in histology room after the organ is delivered to him. Unfortunately the pathophysiological details of the disease how, why, when etc - remained unanswered. Hence the impact on treatment was not drastic as modulation of disease process is possible only if we know how and why and when it occurred. These searching questions continued to stimulate the research in nuclear medicine and outcome has been tremendous in the last few years

  17. Applications of nuclear medicine in genitourinary imaging

    Energy Technology Data Exchange (ETDEWEB)

    Blaufox, M.D.; Kalika, V.; Scharf, S.; Milstein, D.

    1982-01-01

    Major advances in nuclear medicine instrumentation and radiopharmaceuticals for renal studies have occurred during the last decade. Current nuclear medicine methodology can be applied for accurate evaluation of renal function and for renal imaging in a wide variety of clinical situations. Total renal function can be estimated from the plasma clearance of agents excreted by glomerular filtration or tubular secretion, and individual function can be estimated by imaging combined with renography. A major area of radionuclide application is in the evaluation of obstructive uropathy. The introduction of diuretic renography and the use of computer-generated regions of interest offer the clinician added useful data which may aid in diagnosis and management. Imaging is of proven value also in trauma, renovascular hypertension, and acute and chronic renal failure. Methods for the evaluation of residual urine, vesicoureteral reflux, and testicular torsion have achieved increasing clinical use. These many procedures assure a meaningful and useful role for the application of nuclear medicine in genitourinary imaging.

  18. Quality control of nuclear medicine equipment

    International Nuclear Information System (INIS)

    In order to determine functional status and integrity of installations and equipment used in nuclear medicine in everyday medical practice or in research studies, it is important to maintain and implement quality control program. For this type of installation are required high standards, particularly with regard to qualitative and quantitative analysis of the image, and volume measurements in diagnosis and dosimetry. Given the precarious situation of the economy in transition, nuclear medicine departments in the republic, now, can not be always of service contracts with providers of facilities and equipment for routine maintenance and periodic calibration. Therefore, in this article are at some of the quality control procedures should be performed usually by engineers and physicists from the department of nuclear medicine. (authors)

  19. Basics of radiobiology and nuclear medicine

    International Nuclear Information System (INIS)

    The authors successively reveal the topics of the biological impact of radiation (radiobiology) and the diagnostic and the therapeutic application of radiopharmaceuticals (nuclear medicine). Data on the influence of radiation on subcellular, cellular, tissue and organ level are given, on early and late radiation changes, as well. Indication for the application of the different radionuclide methods in the diagnosis of the diseases in the endocrinology, nephrology, cardiology, gastroenterology, haematology of lungs, bones, tumors are pointed out and the main trends of the growing therapeutical use of nuclear medicine are presented. The aim is to teach students the nuclear medicine methods in the complex investigation of the patients, his preliminary preparation and the biological impact of radiation and its risk. Self assessment test for students are proposed and a literature for further reading

  20. Radiopharmaceutical prescription in nuclear medicine departments

    International Nuclear Information System (INIS)

    In France, radiopharmaceutical prescription is often discussed depending to which juridical structure the nuclear medicine department is belonging. According to current regulation, this prescription is an obligation in a department linked to hospital with a pharmacy department inside. But situation remains unclear for independent nuclear medicine departments where physicians are not constrained to prescribe radiopharmaceuticals. However, as radiographers and nurses are only authorized to realize theirs acts in front of a medical prescription, one prescription must be realized. Nowadays, computerized prescription tools have been developed but only for radiopharmaceutical drugs and not for medical acts. In the aim to achieve a safer patient care, the prescription regulation may be applied whatever differences between nuclear medicines departments. (authors)

  1. Exposure from diagnostic nuclear medicine procedures

    International Nuclear Information System (INIS)

    According to our last national study on population exposures from natural and artificial sources of ionizing radiation, 16% of overall annual collective effective dose represent the contribution of diagnostic medical exposures. Of this value, 92% is due to diagnostic X-ray examinations and only 8% arise from diagnostic nuclear medicine procedures. This small contribution to collective dose is mainly the result of their lower frequency compared to that of the X-ray examinations, doses delivered to patients being, on average, ten times higher. The purpose of this review was to reassess the population exposure from in vivo diagnostic nuclear medicine procedures and to evaluate the temporal trends of diagnostic usage of radiopharmaceuticals in Romania. The current survey is the third one conducted in the last decade. As in the previous ones (1990 and 1995), the contribution of the Radiation Hygiene Laboratories Network of the Ministry of Health and Family in collecting data from nuclear medicine departments in hospitals was very important

  2. Nuclear Medicine in a developing country

    International Nuclear Information System (INIS)

    Namibia is a country with 1,8 million inhabitants, of whom the majority has limited access to first world facilities. Nevertheless, medical services of high standard are offered. A Nuclear Medicine Department was established at Windhoek Central Hospital in 1982. A nuclear physician, two nuclear medicine radiographers and a nursing sister staff the department. Equipment includes a Siemens Orbiter and an Elscint Apex SPX Helix gamma camera. Radiopharmaceuticals are obtained from suppliers in South Africa. Investigations performed include musculoskeletal, liver, hepatobiliary, thyroid, renal studies, ventilation perfusion lung scans as well as the following Nuclear Cardiology studies: Gated blood pool scans, Tc-99m pyrophosphate hot spot scans, Tl-201 myocardial perfusion studies, Tc-99m MIBI myocardial perfusion studies and Tl-201 rest-redistribution studies. Problems experienced at the Windhoek Nuclear Medicine department include: Lack of funding and high cost of equipment and radiopharmaceuticals, lack of understanding of Nuclear Medicine by the hospital management and health administrators, and difficulties in procuring short-lived radiopharmaceuticals. Furthermore, the absence of company representatives and spare parts in Namibia leads to loss of time whenever equipment needs to be repaired. Working as the only nuclear medicine physician in a country also poses major problems. Careful management of resources and information drives have helped to sustain the Nuclear Medicine service despite economic problems in the country. Installation of a tele-link between the department in Windhoek Hospital and Tygerberg Hospital in South Africa has greatly assisted to overcome the problem of isolation and lack of back up from fellow specialists. The IAEA has equipped both departments with Hermes workstations (Nuclear Diagnostics) and a tele-link is maintained via modem. The current software provided with the Hermes system is ideally suited to processing of data such as gated

  3. Nuclear medicine with its interdependencies

    International Nuclear Information System (INIS)

    Newly developed nuclear methods and measuring techniques in the diagnosis and therapy of diseases of the blood, heart, vessels, thyroid, gastrointestinal tract, kidneys, skeleton and ophthalmological diseases are described. Occupational radiation exposure is briefly discussed. (AJ)

  4. Calibration of nuclear medicine gamma counters

    International Nuclear Information System (INIS)

    In this paper the practical problem of nuclear medicine gamma counters calibration has been solved by using dose calibrators CRC-15R with standard error ±5%. The samples from technetium generators have been measured both by dose calibrators CRC-15R and gamma counter ICN Gamma 3.33 taking into account decay correction. Only the linear part of the curve has practical meaning. The advantage of this procedure satisfies the requirements from international standards: the calibration of sources used for medical exposure be traceable to a standard dosimetry laboratory and radiopharmaceuticals for nuclear medicine procedures be calibrated in terms of activity of the radiopharmaceutical to be administered. (author)

  5. Role of nuclear medicine in dentistry

    Directory of Open Access Journals (Sweden)

    Shazia Mushtaq

    2013-01-01

    Full Text Available Nuclear medicine studies often play a significant role in the diagnosis and treatment of oral and maxillofacial diseases. While not commonly used in everyday dental practice, the dental provider should have a conversational knowledge of these imaging modalities and understand the indications and limitations of these studies. The purpose of this review is to discuss the nuclear medicine studies that have applications in the head and neck region as well as their indications, limitations, and diagnostic conclusions that can be drawn from these studies.

  6. Basic requirements of nuclear medicine services

    International Nuclear Information System (INIS)

    Technological progress in nuclear medicine continues, not always to the immediate advantage of the developing world. The capital expense, operational demands and maintenance requirements of ever more complex equipment, the consequent need for highly trained staff, the necessity to assure regular supplies of costly radioactive materials, all present problems to which compromise or alternative solutions must often be sought. This chapter constitutes an attempt to define the basic requirements for thr practice of nuclear medicine with respect to staff, equipment, accommodation, supplies and supporting services with particular reference to the needs of institutions in developing countries

  7. Nuclear medicine quality assurance program in Argentina

    International Nuclear Information System (INIS)

    A two steps program has been implemented: the first one is the quality control of the equipment and the second one the development of standard procedures for clinical studies of patients. A training program for doctors and technicians of the nuclear medicine laboratories was carried out. Workshops on instrumentation and quality assurance in nuclear medicine have been organized in several parts of the country. A joint program of the CNEA and the University of Buenos Aires has trained medical physicists. A method has been established to evaluate the capability of the laboratories to produce high quality images and to follow up the implementation of the quality control program

  8. Clinical demands on nuclear medicine in neurology

    International Nuclear Information System (INIS)

    Nuclear medicine techniques can be used which are able to estimate various physiologic variables regionally in the brain. As a disadvantage of these modalities imaging function rather than morphology of brain tissue the coarse spatial resolution inherent to all isotope techniques when compared to CT and magnetic resonance imaging of protons must be accepted. The main demand on nuclear medicine techniques must therefore be the quantitation of physiologic and pathologic processes which are necessary for the understanding of pathophysiology of lesions visualized by modalities imaging morphology. (orig./MG)

  9. The positron camera in nuclear medicine

    International Nuclear Information System (INIS)

    Positron emission tomography is making headway in health care delivery. With improvements in instrumentation and physiologic tracers and with the development of hospital-based compact cyclotrons, 'physiopathologic tomography' is around the corner in nuclear medicine. This paper is a brief review of positron emission tomography: instrumentation and applications

  10. VIIIth international symposium on nuclear medicine

    International Nuclear Information System (INIS)

    The conference proceedings contain 92 abstracts of submitted papers dealing with various applications of radioisotopes in diagnosis and therapy. The papers were devoted to scintiscanning, radioimmunoassay, tomography, the applications of nuclear magnetic resonance and electron microscopy in different branches - oncology, cardiology, neurology, histology, gynecology, internal medicine, etc. (M.D.)

  11. Dosimetry in Nuclear Medicine Diagnosis and Therapy

    Science.gov (United States)

    Noßke, D.; Mattsson, S.; Johansson, L.

    This document is part of Subvolume A 'Fundamentals and Data in Radiobiology, Radiation Biophysics, Dosimetry and Medical Radiological Protection' of Volume 7 'Medical Radiological Physics' of Landolt-Börnstein - Group VIII 'Advanced Materials and Technologies'. It contains the Section '4.7 Necessity of Patient-Specific Dose Planning in Radionuclide Therapy' of the Chapter '4 Dosimetry in Nuclear Medicine Diagnosis and Therapy'.

  12. Abstracts of the European nuclear medicine congress

    International Nuclear Information System (INIS)

    647 abstracts of oral and poster presentations show the results of applied science and research work in diagnostic and therapeutic nuclear medicine. Experiences with new diagnostic techniques, radiopharmaceuticals and instrumentation (e.g. radioimmunoscintigraphy, different dynamic organ function studies) in the fields of cardiology, endocrinology, gastroenterology, hematology, nephrology, oncology, and pediatrics are published as well as dosimetry problems. (TRV)

  13. Collaborative environment for nuclear medicine training

    Energy Technology Data Exchange (ETDEWEB)

    Brambilla, Claudia Regio; Dalpiaz, Gabriel Goulart; Giraffa, Lucia Maria, E-mail: claudinharb@gmail.co [Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS (Brazil); Silva, Ana Maria Marques da [Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS (Brazil). Dept. de Fisica; Silva Junior, Neivo da [Pontificia Universidade Catolica do Rio Grande do Sul (HSL-PUCRS), Porto Alegre, RS (Brazil). Hospital Sao Lucas; Ferreto, Tiago Coelho; Rose, Cesar Augusto Fonticielha de [Pontificia Universidade Catolica do Rio Grande do Sul (PUCRS), Porto Alegre, RS (Brazil). Inst. de Informatica; Silva, Vinicius Duval da [Pontificia Universidade Catolica do Rio Grande do Sul (FAMED/PUCRS), Porto Alegre, RS (Brazil). Escola de Medicina. Dept. de Patologia e Radiacoes

    2011-05-15

    Objective: To validate the proposal for development of a virtual collaborative environment for training of nuclear medicine personnel. Materials and Methods: Organizational assumptions, constraints and functionalities that should be offered to the professionals in this field were raised early in the development of the environment. The prototype was developed in the Moodle environment, including data storage and interaction functionalities. A pilot interaction study was developed with a sample of specialists in nuclear medicine. Users' opinions collected by means of semi-structured questionnaire were submitted to quantitative and content analysis. Results: The proposal of a collaborative environment was validated by a learning courses of nuclear medicine professionals and considered as an aid in the training in this field. Suggestions for improvements and new functionalities were made. There is a need to establish a program for education of moderators specifically for this environment, considering the different interaction characteristics as the online and conventional teaching methods are compared. Conclusion: The collaborative environment will allow the exchange of experiences and case discussions among professionals from institutions located in different regions all over the country, enhancing the collaboration among them. Thus, the environment can contribute in the early and continued education of nuclear medicine professionals. (author)

  14. Nuclear medicine. 2. rev. and enlarged ed.

    International Nuclear Information System (INIS)

    This second edition of the textbook on nuclear medicine is intended as a comprehensive and explanatory source of current theoretical and practical knowledge required for practical application of nuclear medicine techniques for diagnostics and therapy. The first part of the book deals with general aspects such as physical principles, the labelling and quality control of radiopharmaceuticals, and specific kinetics of some preparations, scanning techniques and the relevant equipment including aspects such as equipment handling, functional monitoring, error sources, patent positioning, as well as radiation protection and the handling of radioactive substances at the place of work. This part also explains the organisational framework of a nuclear medicine practice or department and the professional training and tasks of a radiographer in nuclear medicine. The second part is devoted to specific tasks and techniques for diagnostic assessment of the different body organs, illustrated by examples and summarised in tables given at the end of each chapter. Examples of clinical experience explain the criteria for selection of suitable diagnostic technique. (orig.) With 207 figs., 14 tabs

  15. Collaborative environment for nuclear medicine training

    International Nuclear Information System (INIS)

    Objective: To validate the proposal for development of a virtual collaborative environment for training of nuclear medicine personnel. Materials and Methods: Organizational assumptions, constraints and functionalities that should be offered to the professionals in this field were raised early in the development of the environment. The prototype was developed in the Moodle environment, including data storage and interaction functionalities. A pilot interaction study was developed with a sample of specialists in nuclear medicine. Users' opinions collected by means of semi-structured questionnaire were submitted to quantitative and content analysis. Results: The proposal of a collaborative environment was validated by a learning courses of nuclear medicine professionals and considered as an aid in the training in this field. Suggestions for improvements and new functionalities were made. There is a need to establish a program for education of moderators specifically for this environment, considering the different interaction characteristics as the online and conventional teaching methods are compared. Conclusion: The collaborative environment will allow the exchange of experiences and case discussions among professionals from institutions located in different regions all over the country, enhancing the collaboration among them. Thus, the environment can contribute in the early and continued education of nuclear medicine professionals. (author)

  16. Traumatic Brain Injury: Nuclear Medicine Neuroimaging

    NARCIS (Netherlands)

    Sánchez-Catasús, Carlos A; Vállez Garcia, David; Le Riverend Morales, Eloísa; Galvizu Sánchez, Reinaldo; Dierckx, Rudi; Dierckx, Rudi AJO; Otte, Andreas; de Vries, Erik FJ; van Waarde, Aren; Leenders, Klaus L

    2014-01-01

    This chapter provides an up-to-date review of nuclear medicine neuroimaging in traumatic brain injury (TBI). 18F-FDG PET will remain a valuable tool in researching complex mechanisms associated with early metabolic dysfunction in TBI. Although evidence-based imaging studies are needed, 18F-FDG PET i

  17. Nuclear medicine diagnostics of malignant tumors

    International Nuclear Information System (INIS)

    The monography deals with the localization diagnosis in nuclear medicine. After general remarks on technical and physical fundamentals and on methods and devices for scintigraphic localization of malignant tumors, specific scintiscanning of malignancies of thyroid, bones, liver, lungs, pancreas, adrenal glands, brain lymph nodes and eyes is discussed in detail. Numerous relevant references are added to each chapter

  18. Review: radioprotection applied in Nuclear Medicine

    International Nuclear Information System (INIS)

    The aim of this paper is to evaluate the potential causes of exposure to ionizing radiation in a nuclear medicine facility, identifying the causes of common errors in the clinical routine, how to avoid these errors and study good radioprotection practices based on the national law and international documents. (author)

  19. Neuroimaging in nuclear medicine: drug addicted brain

    International Nuclear Information System (INIS)

    Addiction to illicit drugs in one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems in not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis . Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In addition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further

  20. Nuclear medicine and thyroid disease - part II

    International Nuclear Information System (INIS)

    Part 1 of this article discussed the anatomy, physiology and basic pathology of the thyroid gland. Techniques of thyroid scanning and a few clinical examples are shown part II Copyright (2005) The Australian and New Zealand Society Of Nuclear Medicine Inc

  1. Neuroimaging in nuclear medicine: drug addicted brain

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Yong-An; Kim, Dae-Jin [The Catholic University of Korea, Seoul (Korea, Republic of)

    2006-02-15

    Addiction to illicit drugs in one of today's most important social issues. Most addictive drugs lead to irreversible parenchymal changes in the human brain. Neuroimaging data bring to light the pharmacodynamics and pharmacokinetics of the abused drugs, and demonstrate that addiction is a disease of the brain. Continuous researches better illustrate the neurochemical alterations in brain function, and attempt to discover the links to consequent behavioral changes. Newer hypotheses and theories follow the numerous results, and more rational methods of approaching therapy are being developed. Substance abuse is on the rise in Korea, and social interest in the matter as well. On the other hand, diagnosis and treatment of drug addiction is still very difficult, because how the abused substance acts in the brain, or how it leads to behavioral problems in not widely known. Therefore, understanding the mechanism of drug addiction can improve the process of diagnosing addict patients, planning therapy, and predicting the prognosis . Neuroimaging approaches by nuclear medicine methods are expected to objectively judge behavioral and neurochemical changes, and response to treatment. In addition, as genes associated with addictive behavior are discovered, functional nuclear medicine images will aid in the assessment of individuals. Reviewing published literature on neuroimaging regarding nuclear medicine is expected to be of assistance to the management of drug addict patients. What's more, means of applying nuclear medicine to the care of drug addict patients should be investigated further.

  2. Radiation and Radionuclides in Medicine: A Brief Overview of Nuclear Medicine and Radiotherapy

    International Nuclear Information System (INIS)

    In the past two centuries, the field of medicine has seen unprecedented advances. Alongside discoveries like the smallpox vaccine and antibiotics, the discovery of radiation and radionuclides for use in medicine has led to more diverse and effective prevention, diagnostic and treatment options for many health conditions. Diseases like cancer that were once considered unmanageable and fatal can now be diagnosed earlier and treated more effectively using nuclear techniques, giving patients a fighting chance and, for many, a significant chance for a cure. These methods are more important than ever as high-mortality diseases like cancer or cardiovascular diseases are on the rise and are among the leading health threats globally. The IAEA has worked for over 50 years to promote the use of nuclear techniques in medicine by collaborating with its Member States and other organizations through projects, programmes and agreements. The Agency’s aim is to help build Member States’ capacities in this field in order to support the provision of high-quality health care worldwide, particularly in developing countries

  3. Basic Physics for Nuclear Medicine. Chapter 1

    International Nuclear Information System (INIS)

    The technologies used in nuclear medicine for diagnostic imaging have evolved over the last century, starting with Röntgen’s discovery of X rays and Becquerel’s discovery of natural radioactivity. Each decade has brought innovation in the form of new equipment, techniques, radiopharmaceuticals, advances in radionuclide production and, ultimately, better patient care. All such technologies have been developed and can only be practised safely with a clear understanding of the behaviour and principles of radiation sources and radiation detection. These central concepts of basic radiation physics and nuclear physics are described in this chapter and should provide the requisite knowledge for a more in depth understanding of the modern nuclear medicine technology discussed in subsequent chapters

  4. The importance of HIFAR to nuclear medicine

    International Nuclear Information System (INIS)

    Since its official opening on 26 January 1960, the HIFAR research reactor operated by the Australian Nuclear Science and Technology Organisation (ANSTO) at Lucas Heights near Sydney has been used to support an expanding nuclear medicine market. HIFAR has characteristics which make it very suitable for this role and the effect has been to make ANSTO the dominant supplier of reactor-based radiopharmaceuticals in Australia and a significant exporter. While HIFAR has capacity to support limited increased production, its future requires government decisions. The author concluded that the absence of an operational research reactor in Australia and the lack of another local source of neutrons could directly affect the practice of nuclear medicine in the country and the level of presently increasing exports

  5. Quantitative Analysis in Nuclear Medicine Imaging

    CERN Document Server

    2006-01-01

    This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable increase in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of radionuclides for diagnosis and therapy has origins dating back almost to the discovery of natural radioactivity itself, radionuclide therapy and, in particular, targeted radionuclide therapy has only recently emerged as a promising approach for therapy of cancer and, to a lesser extent, other diseases. As effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. ...

  6. Fourth congress of the South African Society of Nuclear Medicine

    International Nuclear Information System (INIS)

    This seminar contains 68 papers. Sixty three papers were indexed. Five papers were considered out of scope for INIS. The implementation of nuclear medicine in the following fields were discussed: neurology, cardiology, monoclonal antibodies, endocrinology, nuclear medicine physics, and radiopharmacy

  7. The application of nuclear-medicine methods in veterinary medicine

    International Nuclear Information System (INIS)

    X-radiography and ultrasound imaging are well established and widely used in veterinary practice, but it is not the same situation with radioisotope imaging. In veterinary practice the above mentioned methods of nuclear medicine are developed only in two countries in Europe. That is not doubt due, so bar, to the difficulties in obtaining satisfactory supply of radioisotopes and to the relatively high cost of scanning equipment. However, in collaboration with the Department of Radiation Protection and Nuclear Medicine of the Medical Faculty in Zagreb, Croatia, we have chance to develop the use of those methods in clinical veterinary practice in Zagreb. That is way in this paper an overview of the application of radioisotopes imaging in veterinary medicine is given. In small animals skeletal changes, lung perusions, brain lesions, space occupying lesions in the liver and its function and hearth function can be usefully searched by a gamma camera and its associated computer. In equine practice scintigraphy of bones, liver, hearth, pulmonary circulation and ventilation is described. The largest amount of radioactive material is used during gamma camera scanning of the skeletons of horses. In this cases the radiation dose 1-2 m from the animal is approximately 3 μSv/h. That is why the protection of personal involved in radioisotope scanning in veterinary medicine must be also regulated by low of radiation protection. Also, the animals should be confined to a controlled area for 2-3 days after scanning before being returned to their owners. After this period the area must be cleaned. (author)

  8. Programmatic activities of IAEA in nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine is high-tech medicine. Nevertheless, it is essential for addressing important health problems of people living in developing countries also. Not only is it sometimes expensive to start with, it also involves a lot of technical know-how, requiring transfer of technology from developed to the developing countries. The rapid development of nuclear medicine, of sophisticated instrumentation and radiopharmaceuticals has resulted in an enormous increase in costs and in the need for maintaining quality. These constitute a challenge and a venture when promoting nuclear medicine globally and particularly in developing countries. No other international organization except IAEA has any specific mandate for application of nuclear energy in the area of human health. WHO has no specific programin nuclear medicine, hence the importance of IAEA's involvement. The IAEA has, ever since its inception, given high priority to enhancing the awareness and capabilities of developing member states to employ nuclear technology for health care and medical research. Much of the Agency promoted research in nuclear medicine is delivered through the so called co-ordinated research projects (CRPs). The CRPs are normally organised as multi-center, prospective studies so that large volume of scientific data could be generated in a short period of 18-24 months. The research is normally done within an operational frame work, established and co-ordinated by the IAEA. The reason for this is that the results can be compared despite site or country specific differences. The methods and materials used for such studies usually conform to a predetermined standard. The protocols for various investigations, criteria for patient selection, mode of arriving at a final diagnosis and analysis of data from these multi-center studies are normally agreed upon by the Chief Scientific Investigators from each participating institution and the IAEA prior to the start of the actual work programme. The

  9. Status of nuclear medicine in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Lee, M.H. (Seoul National Univ. (Republic of Korea). Coll. of Medicine)

    1982-03-01

    The medical application of nuclear medicine in Korea finds its origin in June, 1959, when radioactive iodine therapy was given to a patient with hyperthyroidism, while the legal background for the medical uses of radioisotopes was provided by the Atomic Energy Law promulgated in 1958. The real active application of radioisotope in clinical medicine, however, was made possible as the Radioisotope Clinic was opened at the Seoul National University Hospital in April, 1960. In the early 1960's four medical institutes had radioisotope facilities including scintiscanners, scintillation counters, detectors and spectrometers some of which were provided by the United States Atomic Energy Commission. And now, radioisotopes were applied in 45 medical institutes. At the beginning, thyroid function tests and ferrokinetic studies were primary clinical applications. Scanning of various organs became generalized with the wide use of the photoscanners from 1964 and scintillation cameras from 1969. A new era in the development of the nuclear medicine has started in March, 1979 with the use of computer system in the dynamic studies including radionuclide cardiac angiography and sequential renal scan. At present 13 gamma cameras and 4 computer systems were used in the field of nuclear medicine. Radioimmunoassay techniques began to be used from 1969 and at present about fifty items of tests are being performed for the research purposes and clinical applications.

  10. European Association of Nuclear Medicine congress. Abstracts

    International Nuclear Information System (INIS)

    To assess the exact place of nuclear medicine studies in the clinical environment in consensus with clinicians and radiologists will probably be our most important task during the coming year. Our society cannot afford unnecessary duplication of diagnostic tests but neither should our patients suffer from the failure to use procedures which could change the outcome of their illness or avoid unnecessary pain and costs because of ignorance, or even worse, self defence by larger and thus stronger pressure groups. Defeatism is as inappropriate as remaining in the splendid isolation of our professional and scientific organisations. There is no place for excessive humbleness either, most of the unnecessary procedures performed in modern medicine lie within the domain of other specialists. It is our duty to participate as actors in the thorough reappraisal of the medical, social and economic context of our activity in the interst of our field and our patients. By confronting our ideas and knowledge with those of others, by using our inventiveness to transfer important results from research laboratories to clinical practice and vice versa, by concentrating on the essential rather than pursuing all possible directions, we will be able to influence positively the future of nuclear medicine. There is no better way to develop our speciality than by understanding the clinical issues, by being able to communicate with our clinical partners and by performing common studies on the clinical impact, cost-efficiency and cost-benefit of nuclear medicine procedures. (orig./AJ)

  11. Perspectives in nuclear medicine: pulmonary studies

    International Nuclear Information System (INIS)

    Since the introduction of I-131 labeled macroaggregates in 1964, noninvasive techniques involving injection of radiolabeled agents and remote detection of emitted radiation have become well established in detecting pulmonary disorders in routine clinical medicine. In the past, pulmonary nuclear medicine has been dominated by studies that depict the distribution of pulmonary perfusion and/or ventilation-perfusion balance (e.g., for the detection of pulmonary embolism, obstructive airway disease, lung carcinoma). With the recent development of emission tomography and the potential for new, function-oriented radiopharmaceuticals, however, pulmonary nuclear medicine is entering a new era. The status of contemporary pulmonary nuclear medicine is briefly reviewed in several areas of major interest and applications and focus on areas where new developments are needed and seem feasible in the near future. Several important regional physiological processes measurable by these techniques include: (a) the presence or absence of pulmonary embolism, (b) relative pulmonary blood flow, (c) permeability to specific molecules, (d) lung tissue metabolism, (e) ventilation distribution and (f) the relationship between ventilation and blood flow (perfusion)

  12. Hospital Intranet and Extranet in nuclear medicine

    International Nuclear Information System (INIS)

    Since two years ago nuclear medicine service of Laennec Hospital has implemented transmission and distribution networks of scintigraphic images. A new stage was reached at present by developing an Intranet and Extranet system for nursing units and other services of nuclear medicine. The Intranet link to the services of Laennec Hospital and AP HP is based on a image server connected to the service gamma camera and, after a possible post-processing, the images are transmitted in PCX format by e-mail, attached to the medical record. For communication between nuclear medicine services, a heavier procedure making use of a program for image processing under inter-file standards has been implemented. To achieve the Extranet link with services and physicians of town, exterior to AP HP, a procedure was installed which allows reaching any nursing unit or town physicians having at their disposal e-mail on a secured network. This procedure will be generalized when the Health secured network, linking the medical bodies to Health insurance institutions, will be operational. The interactive tele-medicine will be achieved by means of a procedure based on Internet cooperative tools (wild cards, video- and vision-conferences) which will permits in all situations an interactive work on all the transmitted patient files

  13. History and Perspectives of Nuclear Medicine in Thailand

    OpenAIRE

    Sombut Boonyaprapa

    2014-01-01

    In 1955, the first nuclear medicine division was established in Thailand by Professor Romsai Suwannik in the Department of Radiology, Siriraj Hospil, Mahidol University in Bangkok. In 1959 four years later, the second nuclear medicine division was established in the Department of Radiology, Chulalongkorn Hospital in Bangkok. The third nuclear medicine division was started in Rajvithi Hospital in Bangkok in 1961. The fourth nuclear medicine division was installed in Chiang Mai University which...

  14. Checklists for quality assurance and audit in nuclear medicine

    International Nuclear Information System (INIS)

    A series of checklists are given which aim to provide some guidance to staff in determining whether their working procedures in nuclear medicine are likely to produce a good service and avoid mistakes. The checklists relate to the special equipment used in nuclear medicine departments, radiopharmaceuticals, nuclear medicine staff, services to medical and other hospital staff and finally the service to patients. The checklists are relevant to an average nuclear medicine department performing less than 2000 imaging studies per year. (U.K.)

  15. Proceedings of the Korean Society Nuclear Medicine Autumn Meeting 2002

    International Nuclear Information System (INIS)

    This proceedings contains articles of 2002 autumn meeting of the Korean Society Nuclear Medicine. It was held on November 15-16, 2002 in Seoul, Korea. This proceedings is comprised of 5 sessions. The subject titles of session are as follows: Cancer, Physics of nuclear medicine, Neurology, Radiopharmacy and biology, General nuclear medicine. (Yi, J. H.)

  16. Coded-aperture imaging in nuclear medicine

    Science.gov (United States)

    Smith, Warren E.; Barrett, Harrison H.; Aarsvold, John N.

    1989-01-01

    Coded-aperture imaging is a technique for imaging sources that emit high-energy radiation. This type of imaging involves shadow casting and not reflection or refraction. High-energy sources exist in x ray and gamma-ray astronomy, nuclear reactor fuel-rod imaging, and nuclear medicine. Of these three areas nuclear medicine is perhaps the most challenging because of the limited amount of radiation available and because a three-dimensional source distribution is to be determined. In nuclear medicine a radioactive pharmaceutical is administered to a patient. The pharmaceutical is designed to be taken up by a particular organ of interest, and its distribution provides clinical information about the function of the organ, or the presence of lesions within the organ. This distribution is determined from spatial measurements of the radiation emitted by the radiopharmaceutical. The principles of imaging radiopharmaceutical distributions with coded apertures are reviewed. Included is a discussion of linear shift-variant projection operators and the associated inverse problem. A system developed at the University of Arizona in Tucson consisting of small modular gamma-ray cameras fitted with coded apertures is described.

  17. Converting energy to medical progress [nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-04-01

    For over 50 years the Office of Biological and Environmental Research (BER) of the United States Department of Energy (DOE) has been investing to advance environmental and biomedical knowledge connected to energy. The BER Medical Sciences program fosters research to develop beneficial applications of nuclear technologies for medical diagnosis and treatment of many diseases. Today, nuclear medicine helps millions of patients annually in the United States. Nearly every nuclear medicine scan or test used today was made possible by past BER-funded research on radiotracers, radiation detection devices, gamma cameras, PET and SPECT scanners, and computer science. The heart of biological research within BER has always been the pursuit of improved human health. The nuclear medicine of tomorrow will depend greatly on today's BER-supported research, particularly in the discovery of radiopharmaceuticals that seek specific molecular and genetic targets, the design of advanced scanners needed to create meaningful images with these future radiotracers, and the promise of new radiopharmaceutical treatments for cancers and genetic diseases.

  18. Nuclear medicine: a public health issue

    International Nuclear Information System (INIS)

    Nuclear medicine offers a broad range of services for numerous diseases. By introducing radioactive molecules in the body, nuclear medicine can perform powerful and targeted acts from diagnostic to treatment. In western countries, one out of 2 people will benefit from it during his life, but the producers of radioactive nuclides are not very numerous. In France 80% of the scans are performed with Technetium-99m (99mTc) that is obtained from Molybdenum 99 (99Mo) produced in nuclear reactors. A shortage of 99mTc is expected during next years since the Osiris reactor is planned to be decommissioned at the end of 2015 and other reactors will be stopped for maintenance operations. The different techniques used in nuclear medicine brings contamination risks for both patients and medical staff. These risks are mitigated through an optimization of the dose delivered to the patient, the staff is monitored with the wearing of a dosimeter and is committed to regular medical tests and the handling of radioactive materials is made behind adequate biological shields. Radiation protection in the medical sector is submitted to time-consuming procedures that might be made more flexible and the knowledge of how other countries deal concretely with radiation protection would be beneficial. (A.C.)

  19. Converting energy to medical progress [nuclear medicine

    International Nuclear Information System (INIS)

    For over 50 years the Office of Biological and Environmental Research (BER) of the United States Department of Energy (DOE) has been investing to advance environmental and biomedical knowledge connected to energy. The BER Medical Sciences program fosters research to develop beneficial applications of nuclear technologies for medical diagnosis and treatment of many diseases. Today, nuclear medicine helps millions of patients annually in the United States. Nearly every nuclear medicine scan or test used today was made possible by past BER-funded research on radiotracers, radiation detection devices, gamma cameras, PET and SPECT scanners, and computer science. The heart of biological research within BER has always been the pursuit of improved human health. The nuclear medicine of tomorrow will depend greatly on today's BER-supported research, particularly in the discovery of radiopharmaceuticals that seek specific molecular and genetic targets, the design of advanced scanners needed to create meaningful images with these future radiotracers, and the promise of new radiopharmaceutical treatments for cancers and genetic diseases

  20. Converting Energy to Medical Progress [Nuclear Medicine

    Science.gov (United States)

    2001-04-01

    For over 50 years the Office of Biological and Environmental Research (BER) of the United States Department of Energy (DOE) has been investing to advance environmental and biomedical knowledge connected to energy. The BER Medical Sciences program fosters research to develop beneficial applications of nuclear technologies for medical diagnosis and treatment of many diseases. Today, nuclear medicine helps millions of patients annually in the United States. Nearly every nuclear medicine scan or test used today was made possible by past BER-funded research on radiotracers, radiation detection devices, gamma cameras, PET and SPECT scanners, and computer science. The heart of biological research within BER has always been the pursuit of improved human health. The nuclear medicine of tomorrow will depend greatly on today's BER-supported research, particularly in the discovery of radiopharmaceuticals that seek specific molecular and genetic targets, the design of advanced scanners needed to create meaningful images with these future radiotracers, and the promise of new radiopharmaceutical treatments for cancers and genetic diseases.

  1. Nuclear medicine procedures in lung cancer

    International Nuclear Information System (INIS)

    Although radiography, computed tomography and magnetic resonance imaging are still the methods of choice for the study of lung cancer, they have certain limitations in the determination of the nature of suspicious lung nodules, the evaluation of mediastinal involvement, the assessment of the viability of previously treated lesions and the diagnosis of tumour relapse. There is a wide range of current oncological requirements related to lung cancer: detection of malignant lesions at the earliest stage and in the most effective way; the definition of the biological characteristics of a lesion (proliferation, aggressiveness, differentiation, etc.); the need to define the operability of the patient (function of residual lung and staging); and the need to evaluate the behaviour of the tumour (response to therapy, early detection of recurrences, metastatic spread). Most of the efforts of the nuclear medicine community have been focussed on diagnosis, staging, restaging and therapy monitoring of lung cancer. Many radiopharmaceuticals have been employed for this, including gallium, monoclonal antibodies, somatostatin analogues, lipophilic cations and positron emission tracers. There is ample evidence that nuclear medicine techniques may provide complementary information with respect to anatomical imaging, for example in the assessment of preoperative function by means of ventilation and perfusion scintigraphy, or in tumour localisation by means of specific tumour-seeking agents. However, clinical data suggest that, when properly used, nuclear medicine procedures in some cases may be not only complementary to radiology but essential for the clinical management of lung cancer. An example of such a procedure is fluorodeoxyglucose positron emission tomography (FDG PET) the introduction of which has greatly contributed to confirmation of the clinical value of nuclear medicine in this field. FDG PET has proved of great help in lung cancer management and its cost-effectiveness in

  2. Radionuclides for nuclear medicine: a nuclear physicists' view

    DEFF Research Database (Denmark)

    Cantone, M.; Haddad, F.; Harissopoulos, S.; Jensen, Mikael; Jokinen, A.; Köster, U.; Lebeda, O.; Ponsard, B.; Ratzinger, U.; Stora, T.; Tarkanyi, F.; Van Duppen, P.

    NuPECC (the Nuclear Physics European Collaboration Committee, an expert committee of the European Science Foundation) has the mission to strengthen European Collaboration in nuclear science through the promotion of nuclear physics and its trans-disciplinary use and application. NuPECC is currently...... working on a report on “Nuclear Physics for Medicine” and has set up a working group to review the present status and prospects of radionuclides for nuclear medicine. An interim report will be presented to seek comments and constructive input from EANM members. In particular it is investigated how nuclear...... physics Methods and nuclear physics facilities are supporting the development and supply of medical radionuclides and how this support could be further strengthened in future. Aspects that will be addressed: •In recent years, the reactor-based supply chain of 99Mo/99mTc generators was repeatedly...

  3. Radionuclides for nuclear medicine: a nuclear physicists' view

    DEFF Research Database (Denmark)

    Cantone, M.; Haddad, F.; Harissopoulos, S.;

    2013-01-01

    NuPECC (the Nuclear Physics European Collaboration Committee, an expert committee of the European Science Foundation) has the mission to strengthen European Collaboration in nuclear science through the promotion of nuclear physics and its trans-disciplinary use and application. NuPECC is currently...... working on a report on “Nuclear Physics for Medicine” and has set up a working group to review the present status and prospects of radionuclides for nuclear medicine. An interim report will be presented to seek comments and constructive input from EANM members. In particular it is investigated how nuclear...... physics Methods and nuclear physics facilities are supporting the development and supply of medical radionuclides and how this support could be further strengthened in future. Aspects that will be addressed: •In recent years, the reactor-based supply chain of 99Mo/99mTc generators was repeatedly...

  4. [Civilization stress, cardiovascular risk, evidence-based medicine, guidelines].

    Science.gov (United States)

    Simon, Kornél

    2009-05-10

    Cardiovascular diseases have the pole-position on the list of morbidity and mortality statistics. Despite the great advances have been made in management of cardiovascular diseases, prevalence of these disorders increases worldwide, and even younger and younger ages are threatened. This phenomenon is strongly related to obesity and type 2 diabetes pandemic, which shows an unequivocal association with expansion of modernized life-style. The pathomechanism proposed to have central role is the chronic stress induced by civilized life-conduct. The authors criticizes the everyday practice suggested for management of cardiovascular diseases, focusing on normalization of cardiovascular risk factors, instead of fighting against the primary cause ie. chronic stress. There is growing evidence, that achieving the target values defined in guide-lines will not necessarily result in improvement of patient related clinical outcomes. The statistical approach generally practiced in randomized clinical trials is primarily striving for the drug-sale, instead of discovering novel pathophysiological relations. Pharmaceutical industry having decisive role in research and patient-care is mainly interested in profit-sharing, therefore patients' interest can not be optimally realized, and costs are unnecessarily augmented. Separation of patient-, and business-oriented medical care is an ethical question of fundamental importance. PMID:19403433

  5. Genomics and proteomics in nuclear medicine

    International Nuclear Information System (INIS)

    The results obtained from basic science deliver more information about many new molecular structures, which may serve as potential new diagnostic or even therapeutic targets. The selection and evaluation of these targets needs information concerning physiology, biochemistry and pharmacology. These data can be obtained at least in part by nuclear medicine technology. Nuclear medicine procedures can be applied for the assessment of the function and regulation of genes. This can be achieved by use of radiolabeled antisense molecules or reporter gene technology. New therapeutic approaches necessitate biodistribution studies at preclinical stages and methods delivering data about their effectiveness. Finally, procedures from biotechnology such as phagen display may be used for the development of new biomolecules for the isotope-based diagnostics and treatment. (orig.)

  6. New developments in nuclear medicine technology

    International Nuclear Information System (INIS)

    During the past few years, there have been new impulses in the development of a number of technologies employed in Nuclear Medicine imaging. These include new scintillation materials, the way of detecting the scintillation light, and completely novel methods to detect gamma rays by means of semiconductor detectors. In addition to combined instrumentation that can be used for SPECT and PET, already in clinical use, combined scintigraphic and anatomic imaging devices are now becoming available, for example SPECT/CT or PET/CT. This review article describes the most important of the new components, part of which have already entered product development and part of which are still in the research phase. The review focus on the employment of modern semiconductor detectors in Nuclear Medicine. (orig.)

  7. Breast cancer. Diagnostic nuclear medicine and radiology

    International Nuclear Information System (INIS)

    The book focuses on the presentation of long established and recently developed nuclear medicine techniques for diagnostic evaluation of carcinoma of the mammary gland and the metastases, primarily scintigraphy and positron emission tomography (PET). The methodological information is enhanced by information on the latest results obtained of the methods not yet applied as techniques of clinical routine. The current techniques of diagnostic radiology are discussed in the framework of a critical review of results and restraints of all diagnostic methods available at present. Special emphasis is placed on elaborating the comparative assessment along the line of the catalogue of clinical, diagnostic objectives or problems and the resulting clinical rating. The material thus gives a comprehensive, up-to-date overview of well-known and recent methods of diagnostic nuclear medicine in comparison to the established radiological imaging methods. (orig./CB)

  8. Directory of computer users in nuclear medicine

    International Nuclear Information System (INIS)

    The Directory of Computer Users in Nuclear Medicine consists primarily of detailed descriptions and indexes to these descriptions. A typical Installation Description contains the name, address, type, and size of the institution and the names of persons within the institution who can be contacted for further information. If the department has access to a central computer facility for data analysis or timesharing, the type of equipment available and the method of access to that central computer is included. The dedicated data processing equipment used by the department in its nuclear medicine studies is described, including the peripherals, languages used, modes of data collection, and other pertinent information. Following the hardware descriptions are listed the types of studies for which the data processing equipment is used, including the language(s) used, the method of output, and an estimate of the frequency of the particular study. An Installation Index and an Organ Studies Index are also included

  9. Formulary: Pharmacologic interventions in nuclear medicine

    International Nuclear Information System (INIS)

    The purpose of this formulary is to provide the practitioner with a readily available reference addressed specifically at the pharmacology (i.e., chemistry, mechanism(s) of action, cautions, dosage, and available preparation(s)) of interventional drugs commonly used in nuclear medicine practice. Although the majority of these agents are intended for alternate therapeutic indications, the formulary is directed at and limited to information pertinent to their interventional use. In this regard, the majority of the presented material has been extrapolated from standard drug formularies or product inserts. Specific material related to published interventional nuclear medicine studies is referenced in the bibliography and/or can be found in the associated chapters of this book. The reader is advised to note not only the information related to the interventional drug, but also the statements regarding appropriate treatment or avoidance of associated side effects. To facilitate utilization, the interventional drugs are listed in alphabetical order, rather than by therapeutic class

  10. Directory of computer users in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Erickson, J.J.; Gurney, J.; McClain, W.J. (eds.)

    1979-09-01

    The Directory of Computer Users in Nuclear Medicine consists primarily of detailed descriptions and indexes to these descriptions. A typical Installation Description contains the name, address, type, and size of the institution and the names of persons within the institution who can be contacted for further information. If the department has access to a central computer facility for data analysis or timesharing, the type of equipment available and the method of access to that central computer is included. The dedicated data processing equipment used by the department in its nuclear medicine studies is described, including the peripherals, languages used, modes of data collection, and other pertinent information. Following the hardware descriptions are listed the types of studies for which the data processing equipment is used, including the language(s) used, the method of output, and an estimate of the frequency of the particular study. An Installation Index and an Organ Studies Index are also included. (PCS)

  11. Extracts from IAEA's Resources Manual in Nuclear Medicine. Part-3: Establishing Nuclear Medicine Services

    International Nuclear Information System (INIS)

    In the past, consideration was given to the categories of nuclear medicine ranging from simple imaging or in-vitro laboratories, to more complex departments performing a full range of in-vitro and in-vivo procedures that are also involved in advanced clinical services, training programmes, research and development. In developing countries, nuclear medicine historically has often been an offshoot of pathology, radiology or radiotherapy services. These origins are currently changing as less radioimmunoassay is performed and fully-fledged, independent departments of nuclear medicine are being set up. The trend appears to be that all assays (radioassay or ELISA) are done in a biochemistry laboratory whereas nuclear medicine departments are involved largely in diagnostic procedures, radionuclide therapy and non-imaging in-vitro tests. The level of nuclear medicine services is categorized according to three levels of need: Level 1: Only one gamma camera is needed for imaging purposes. The radiopharmaceutical supply, physics and radiation protection services are contracted outside the centre. Other requirements include a receptionist and general secretarial assistance. A single imaging room connected to a shared reporting room should be sufficient, with a staff of one nuclear medicine physician and one technologist, with back-up. This level is appropriate for a small private practice. Level 2: This is suitable for a general hospital where there are multiple imaging rooms where in-vitro and other non-imaging studies would generally be performed as well as radionuclide therapy. Level 3: his is appropriate for an academic institution where there is a need for a comprehensive clinical nuclear medicine service, human resource development and research programmes. Radionuclide therapy for in-patients and outpatients is provided

  12. Medical isotopes and emerging nuclear medicine technologies

    International Nuclear Information System (INIS)

    This presentation discusses medical isotopes and the emerging nuclear medicine technologies as well as the impact of Chalk River reactor shutdown on patient management and diseases. It outlines the chain of supply of isotopes across the globe and isotope shortage impact. It recommends the following mitigating strategies: modifications of scanning techniques, adjustment of patient scheduling, optimization of Tc-99m generator use, patient prioritization, alternate procedures and PET scanning.

  13. A nuclear chocolate box: the periodic table of nuclear medicine.

    Science.gov (United States)

    Blower, Philip J

    2015-03-21

    Radioisotopes of elements from all parts of the periodic table find both clinical and research applications in radionuclide molecular imaging and therapy (nuclear medicine). This article provides an overview of these applications in relation to both the radiological properties of the radionuclides and the chemical properties of the elements, indicating past successes, current applications and future opportunities and challenges for inorganic chemistry. PMID:25406520

  14. Nuclear medicine solutions in winter sports problems

    International Nuclear Information System (INIS)

    Full text: The diagnostic workup of acute Winter Sports injuries is done by Conventional X Ray, CT and MRI. Chronic injuries as stress reactions are best investigated by Nuclear Medicine procedures: Snow Boarding: In Snow-Boarding chronic injuries are mostly seen as local increased uptake laterally in the lower third of the Fibula of the front leg together with Tibial increase medially in the other leg. Skiing: Chronic Skiing injuries are less asymmetrical and mostly seen on the apex of the patella. Chronic Feet Problems: A different chronic problem is the reduced blood perfusion in the feet if hard, tightened boots are used for longer time by professional ski instructors and racers. Flow difference between the foot in the boot and the other without boot are dramatic as measured by Nuclear Medicine Procedures and MRI. Pulmonary Embolism: Acute pulmonary embolism caused by thrombi originating at the site of constant pressure on the back rim of ski boots is not uncommon in older skiers (seek and you will find), but never seen in the younger group of Snow-Boarders. Copyright (2002) The Australian and New Zealand Society of Nuclear Medicine Inc

  15. Hand exposure in nuclear medicine workers

    International Nuclear Information System (INIS)

    As a result of the gamma radiation emitted by radioactive elements (e.g. 99mTc and 131I) used in nuclear medicine laboratories for diagnostic and therapeutic purposes, nuclear medicine workers are exposed to whole-body doses. These doses are usually measured by using individual film dosemeters. Lead or lead glass shields used during the handling of radioisotope minimise the whole-body dose received. Nevertheless, part of the job has to be performed manually, hence the hands are more exposed to radiation. This paper presents the results of measuring the equivalent dose to the hands of workers employed in five selected nuclear medicine laboratories where technetium and iodine radioisotopes are in common use. Sixty workers, including physicians, nurses, radiopharmacists and technicians, were included in the study. Doses were measured at 1 month intervals. The study indicated that, in some instances, the danger of radiation dose to the hand may be significant. Monthly doses exceed 50 mSv, which may suggest that an annual dose may be higher than 500 mSv. (author)

  16. Justification of the hybrid nuclear medicine examinations

    International Nuclear Information System (INIS)

    The annual frequency of nuclear medicine examinations is increasing worldwide. This is partly a consequence of the recently introduced single photon emission tomography, combined with computed tomography, and positron emission tomography, combined with computed tomography, techniques, which combine functional, metabolic and morphological information important for the diagnosis of many diseases. However, since the effective radiation dose is the sum of the dose of two components, the hybrid examinations result in increased patient exposure. Accordingly, their justification becomes mandatory. It starts with their clinical importance-the opportunity to resolve a clinical problem decisive for patients' management. Knowledge of the indications, contraindications and the examinations' limitations is the responsibility of the nuclear medicine physician, as well as the choice of the most adequate examination and protocol. In conclusion, the cost and the accessibility of the examinations should not be the principal consideration as opposed to the diagnostic value and the exposure. Flexible protocols and algorithms should be used for hybrid nuclear medicine examinations. (authors)

  17. Impact of Obesity on Nuclear Medicine

    International Nuclear Information System (INIS)

    Obesity with its alarming increase in number among adults and children represents a significant health problem with serious medical, social, psychological and economical reverberations. The burden that is put upon the medical care system due to this problem has a significant effect on the medical services provided including radiological imaging. The effect of obesity on nuclear medicine services includes many aspects starting with problems with patient preparation prior to imaging, while radiotracer administration and during patient imaging. In addition, altered imaging techniques, including timing, imaging duration, and protocol alteration. Furthermore, obtaining suboptimal images brought by artifacts due to soft tissue attenuation and incomplete whole body coverage during image acquisition and performing sub optimal quantification, especially in positron emission tomography. Finally, dealing with mechanical problems such as weight limits of the imaging table and bore size in PET or SPECT/CT. These issues are discussed in this review clarifying the impact of this epidemic health problem on the nuclear medicine services and possible solutions to overcome the difficulties encountered in the nuclear medicine department. (author)

  18. Proceedings of 2nd Korea-China Congress of Nuclear Medicine and the Korean Society Nuclear Medicine Spring Meeting 2000

    International Nuclear Information System (INIS)

    This proceedings contains articles of 2nd Korea-China Congress of Nuclear Medicine and 2000 spring meeting of the Korean Society Nuclear Medicine. It was held on May 17-19, 2000 in Seoul, Korean. This proceedings is comprised of 6 sessions. The subject titles of session are as follows: general nuclear medicine, neurology, oncology, radiopharmacy and biology, nuclear cardiology, nuclear cardiology: physics and instrumentation and so on. (Yi, J. H.)

  19. Radiopharmaceuticals in Nuclear Medicine: Evolution and Role in Dentistry

    OpenAIRE

    Vani, Chappidi; Nagalaxmi, V.; Singh, Anshul; Zardi, Faisal Taiyebali; Lalitha, CH

    2013-01-01

    NUCLEAR MEDICINE is the branch of medicine and medical imaging that uses radiation emitted by a radio-pharmaceutical to provide information about both the structure and function of organ systems within the body thereby aiding in the diagnosis and treatment of a disease. This unparalleled branch of radiology concerns with the diagnostic and therapeutic use of radionuclides. The most striking feature that distinguishes Nuclear Medicine from other Imaging Modalities is that Nuclear Medicine aids...

  20. Basic science of nuclear medicine the bare bone essentials

    CERN Document Server

    Lee, Kai H

    2015-01-01

    Through concise, straightforward explanations and supporting graphics that bring abstract concepts to life, the new Basic Science of Nuclear Medicine—the Bare Bone Essentials is an ideal tool for nuclear medicine technologist students and nuclear cardiology fellows looking for an introduction to the fundamentals of the physics and technologies of modern day nuclear medicine.

  1. Handbook of nuclear medicine practice in developing countries

    International Nuclear Information System (INIS)

    This ''Handbook of Nuclear Medicine Practices in the Developing Countries'' is meant primarily for those, who intend to install and practice nuclear medicine in a developing country. By and large, the conventional Textbooks of nuclear medicine do note cater to the special problems and needs of these countries. The Handbook is not trying to replace these textbooks, but supplement them with special information and guidance, necessary for making nuclear medicine cost-effective and useful in a hospital of a developing country. It is written mostly by those, who have made success in their careers in nuclear medicine, in one of these countries. One way to describe this Handbook will be that it represents the ways, in which, nuclear medicine is practised in the developing countries, described by those, who have a long and authentic experience of practising nuclear medicine in a developing country

  2. The development of nuclear medicine in Slovenia and Ljubljana; half a century of nuclear medicine in Slovenia:

    OpenAIRE

    Gaberšček, Simona; Zupanič Slavec, Zvonka; Slavec, Ksenija

    2012-01-01

    Background Nuclear medicine began to be developed in the USA after 1938 when radionuclides were introduced into medicine and in Europe after radionuclides began to be produced at the Harwell reactor (England, 1947). Slovenia began its first investigations in the 1950s. This article describes the development of nuclear medicine in Slovenia and Ljubljana. The first nuclear medicine interventions were performed in Slovenia at the Internal Clinic in Ljubljana in the period 1954–1959. In 1954, Dr ...

  3. Nuclear medicine resources in the internet

    International Nuclear Information System (INIS)

    The internet is a global collection of networked computers linked by a set of protocols which allows the otherwise disperate computer systems to communicate with each other. In contrast to text-only data available previously, the World Wide Web allows multimedia content to be available on the internet. Graphics can now likewise be used as links. The development of World Wide Web client software such as Mosaic, or the currently more popular Netscape Navigator, makes linking from one document to another (colloquially referred to as 'surfing the Net') fast and simple. While these software are commonly called Web browsers their function extends to the other internet services such as e-mail, file transfer protocol, remote login, Gopher and WAIS. A prototype application being developed as a case-based teaching file which could include clinical data and case discussion, aside of course from the nuclear medicine and related images. Contributions from various institutions can be made available on their own servers and linked together through hypertext. Examples of these are websites of the Mallinckrodt Institute of Radiology and the Joint Program in Nuclear Medicine of the Harvard Medical School. The university of Iowa also has its Virtual Hospital, a collection of clinical cases with radiologic images. Most major universities and medical centers have websites where information on on-going research, facilities and personnel are made available. Links to various special interest discussion groups (e.g. those developing the common image file format) are also accessible and the documents often contain further links to related fields in nuclear technology. The very nature of the hypertext transfer protocol of the World Wide Web makes it a relatively simple matter for a developer of a teaching system to include links to necessary resources. It is envisioned that an internet-based teaching module will be incorporated in some nuclear medicine training programs in the United States

  4. Value measurement of nuclear medicine procedures

    International Nuclear Information System (INIS)

    The difficulty in measuring the benefit component for cost/benefit analysis of diagnostic procedures in medicine is portrayed as a complex issue relating the objective of intent to a classification of types of decisions a physician must make in evaluating a patient's problem. Ultimately, it seems desirable to develop measuring instruments such as attitude measurement tools by which the relative value of alternative diagnostic procedures could be measured in terms of what they contribute to diminishing the patient's personal perception of disease. Even without this idealized objective, it is reasonable to assume that diagnostic tests which do not contain information, defined as a change in the randomness of a state of knowledge, could not be expected to ultimately benefit the patient. Thus diagnostic information should provide a rational direction for the physician to modify the course of the patient's illness. Since information can be measured as a change in randomness of a knowledge state, we can determine the information content of a specific nuclear medicine procedure when faced with an array of diagnostic problems. These measurements remain to be made for clinical nuclear medicine procedures and are currently under study

  5. Nanotechnology and nuclear medicine; research and preclinical applications.

    Science.gov (United States)

    Assadi, Majid; Afrasiabi, Kolsoom; Nabipour, Iraj; Seyedabadi, Mohammad

    2011-01-01

    The birth of nanotechnology in human society was around 2000 years ago and soon found applications in various fields. In this article, we highlight the current status of research and preclinical applications and also future prospects of nanotechnology in medicine and in nuclear medicine. The most important field is cancer. A regular nanotechnology training program for nuclear medicine physicians may be welcome. PMID:21761018

  6. Guidelines on QC for nuclear medicine instrumentation

    International Nuclear Information System (INIS)

    Full text: In 2005, a working group of The European Association of Nuclear Medicine (EANM) was set up to provide nuclear medicine practitioners with general guidelines on the quality control of equipment used in the practice of nuclear medicine. In diagnostic nuclear medicine, the quality assurance objective is the provision of high quality, reproducible data that would provide the required clinical information with the smallest radiation burden to the patient. Quality assurance programmes must ensure the most effective use of available equipment and must ensure that processes are in place to minimize clinical risk. Our guidelines focus on the quality control (QC) procedures used in nuclear medicine with a special focus on new, sophisticated, digital technologies. The guidelines have been written as a tool designed to promote the cost-effective use of high quality nuclear medicine instrumentation and to aid practitioners in ensuring accurate information is obtained from each nuclear medicine examination. The purpose of these guidelines is to assist practitioners in achieving their clinical objective and, as such, they are general recommendations on good practice which should be applicable across national boundaries. Routinely, quality control procedures are required to ensure that nuclear medicine equipment is functioning correctly. These quality control tests are intended to detect problems of the systems before they impact on clinical patient studies. They are not intended to provide a full evaluation of equipment performance. Further tests may be required to trace the cause of the problem and to ensure that the equipment is performing properly after service or adjustment. Our QC guidelines cover both imaging and other measuring (non-imaging) equipment including planar gamma cameras, multi-detector and SPECT cameras, PET and PET/CT imaging systems and dose calibrators, survey meters and gamma counters. Quality control of individual components is necessary to

  7. Absorbed Doses to Patients in Nuclear Medicine

    International Nuclear Information System (INIS)

    The work with a Swedish catalogue of radiation absorbed doses to patients undergoing nuclear medicine investigations has continued. After the previous report in 1999, biokinetic data and dose estimates (mean absorbed dose to various organs and tissues and effective dose) have been produced for a number of substances: 11C- acetate, 11C- methionine, 18F-DOPA, whole antibody labelled with either 99mTc, 111In, 123I or 131I, fragment of antibody, F(ab')2 labelled with either 99mTc, 111In, 123I or 131I and fragment of antibody, Fab' labelled with either 99mTc, 111In, 123I or 131I. The absorbed dose estimates for these substances have been made from published biokinetic information. For other substances of interest, e.g. 14C-urea (children age 3-6 years), 14C-glycocholic acid, 14C-xylose and 14C-triolein, sufficient literature data have not been available. Therefore, a large number of measurements on patients and volunteers have been carried out, in order to determine the biokinetics and dosimetry for these substances. Samples of breast milk from 50 mothers, who had been subject to nuclear medicine investigations, have been collected at various times after administration of the radiopharmaceutical to the mother. The activity concentration in the breast milk samples has been measured. The absorbed dose to various organs and tissues and the effective dose to the child who ingests the milk have been determined for 17 different radiopharmaceuticals. Based on these results revised recommendations for interruption of breast-feeding after nuclear medicine investigations are suggested

  8. NCT program at Nuclear Medicine, Inc

    International Nuclear Information System (INIS)

    The Neutron Capture Therapy program at Nuclear Medicine, Inc. (NMI) is focused on obtaining Food and Drug Administration (FDA) approval of the treatment for malignant brain tumors. To minimize both the time and expense of the approval process, research efforts have been strictly focused and Orphan Drug sponsorship of the boron compound, Na2B12H11SH, has been obtained. The significance of Orphan Drug sponsorship and NMI's initial meeting with the FDA to discuss preclinical and clinical protocols are discussed. 9 references, 2 figures

  9. Artificial neural networks in nuclear medicine

    International Nuclear Information System (INIS)

    An analysis of the accessible literature on the diagnostic applicability of artificial neural networks in coronary artery disease and pulmonary embolism appears to be comparative to the diagnosis of experienced doctors dealing with nuclear medicine. Differences in the employed models of artificial neural networks indicate a constant search for the most optimal parameters, which could guarantee the ultimate accuracy in neural network activity. The diagnostic potential within systems containing artificial neural networks proves this calculation tool to be an independent or/and an additional device for supporting a doctor's diagnosis of artery disease and pulmonary embolism. (author)

  10. [Solid liver mass. Studies with nuclear medicine].

    Science.gov (United States)

    Domínguez Gadea, L; Fernández Salazar, L; García Grávalos, R; Rodríguez Eyré, J L

    2000-04-01

    We present the case of a 23 year old female with two incidentally detected hepatic mass that have not clinically o radiologically specific findings. Nuclear medicine tracers, including colloids and hepatobiliary agents showing the characteristic findings of focal nodular hyperplasia: Hypervascularization, normal uptake of colloids, accumulation of hepatobiliary tracer and hot spots due to the retention of this tracer during the clearance fhase. The patient was underwent hepatectomy. The examination of surgical specimen revealed focal nodular hyperplasia. The scintigraphic studies could be an useful tool in the noninvasive diagnosis of liver masses. PMID:10893773

  11. Nuclear medicine training and practice in Poland

    Energy Technology Data Exchange (ETDEWEB)

    Teresinska, Anna [Institute of Cardiology, Department of Nuclear Medicine, Warsaw (Poland); Birkenfeld, Bozena [Pomeranian Medical University, Department of Nuclear Medicine, Szczecin (Poland); Krolicki, Leszek [Warsaw Medical University, Department of Nuclear Medicine, Warsaw (Poland); Dziuk, Miroslaw [Military Institute of Medicine, Department of Nuclear Medicine, Warsaw (Poland)

    2014-10-15

    In Poland, nuclear medicine (NM) has been an independent specialty since 1988. At the end of 2013, the syllabus for postgraduate specialization in NM has been modified to be in close accordance with the syllabus approved by the European Union of Medical Specialists and is expected to be enforced before the end of 2014. The National Consultant in Nuclear Medicine is responsible for the specialization program in NM. The Medical Center of Postgraduate Training is the administrative body which accepts the specialization programs, supervises the training, organizes the examinations, and awards the specialist title. Specialization in NM for physicians lasts for five years. It consists of 36 months of training in a native nuclear medicine department, 12 months of internship in radiology, 3 months in cardiology, 3 months in endocrinology, 3 months in oncology, and 3 months in two other departments of NM. If a NM trainee is a specialist of a clinical discipline and/or is after a long residency in NM departments, the specialization in NM can be shortened to three years. During the training, there are obligatory courses to be attended which include the elements of anatomy imaging in USG, CT, and MR. Currently, there are about 170 active NM specialists working for 38.5 million inhabitants in Poland. For other professionals working in NM departments, it is possible to get the title of a medical physics specialist after completing 3.5 years of training (for those with a master's in physics, technical physics or biomedical engineering) or the title of a radiopharmacy specialist after completing 3 years of training (for those with a master's in chemistry or biology). At present, the specialization program in NM for nurses is being developed by the Medical Centre of Postgraduate Education. Continuing education and professional development are obligatory for all physicians and governed by the Polish Medical Chamber. The Polish Society of Nuclear Medicine (PTMN) organizes

  12. Nuclear medicine training and practice in Poland

    International Nuclear Information System (INIS)

    In Poland, nuclear medicine (NM) has been an independent specialty since 1988. At the end of 2013, the syllabus for postgraduate specialization in NM has been modified to be in close accordance with the syllabus approved by the European Union of Medical Specialists and is expected to be enforced before the end of 2014. The National Consultant in Nuclear Medicine is responsible for the specialization program in NM. The Medical Center of Postgraduate Training is the administrative body which accepts the specialization programs, supervises the training, organizes the examinations, and awards the specialist title. Specialization in NM for physicians lasts for five years. It consists of 36 months of training in a native nuclear medicine department, 12 months of internship in radiology, 3 months in cardiology, 3 months in endocrinology, 3 months in oncology, and 3 months in two other departments of NM. If a NM trainee is a specialist of a clinical discipline and/or is after a long residency in NM departments, the specialization in NM can be shortened to three years. During the training, there are obligatory courses to be attended which include the elements of anatomy imaging in USG, CT, and MR. Currently, there are about 170 active NM specialists working for 38.5 million inhabitants in Poland. For other professionals working in NM departments, it is possible to get the title of a medical physics specialist after completing 3.5 years of training (for those with a master's in physics, technical physics or biomedical engineering) or the title of a radiopharmacy specialist after completing 3 years of training (for those with a master's in chemistry or biology). At present, the specialization program in NM for nurses is being developed by the Medical Centre of Postgraduate Education. Continuing education and professional development are obligatory for all physicians and governed by the Polish Medical Chamber. The Polish Society of Nuclear Medicine (PTMN) organizes regular

  13. Security in the nuclear medicine department

    International Nuclear Information System (INIS)

    The current threat from terrorism highlights the need for awareness of adequate security of radioactive sources by health bodies to prevent the opportunistic access to, theft of. or accidental loss of sources, together with stringent security measures in place to prevent the international misuse of radioactive sources as a weapon by unauthorised access. This presentation discusses the processes undertaken to ensure the safety and security of radioactive materials within the nuclear medicine department in line with current regulations and guidelines. These include risk assessments, security systems, audit trails, restricted access and personnel background checks

  14. Energy-coded processing in nuclear medicine

    International Nuclear Information System (INIS)

    A method for processing image data which takes into account the energy of each detected gamma-ray photon. Weighted spatial averaging of local detected count densities in radionuclide images can increase the visual detectability of abnormalities. In principle, the benefits of image processing in nuclear medicine can be increased by processing the image data in each interval of the detected photon spectrum using a procedure that is appropriate for the spatial resolution and statistical quality associated with that energy interval, and by combining energy-coded processed image components using generally energy-dependent weights. The potential gains in detection performance by implementation of such an approach are examined

  15. Nuclear medicine: dosimetric considerations: pregnancy and lactation

    International Nuclear Information System (INIS)

    Radiation exposure of pregnant woman in nuclear medicine is important from the point of view of radiological protection. In this report are presented the most relevant considerations for the internal dosimetry during pregnancy and lactation. The dose estimation to the mother and fetus during pregnancy can be made based in MIRD methodology with specific phantoms of the pregnant woman allowing the dose calculation in the first, second and third month of pregnancy, through the MIRDOSE software. The effective doses in infants and recommendations are also explained in this report

  16. Development of Scintillators in Nuclear Medicine.

    Science.gov (United States)

    Khoshakhlagh, Mohammad; Islamian, Jalil Pirayesh; Abedi, Seyed Mohammad; Mahmoudian, Babak

    2015-01-01

    High-quality image is necessary for accurate diagnosis in nuclear medicine. There are many factors in creating a good image and detector is the most important one. In recent years, several detectors are studied to get a better picture. The aim of this paper is comparison of some type of these detectors such as thallium activated sodium iodide bismuth germinate cesium activated yttrium aluminum garnet (YAG: Ce) YAP: Ce "lutetium aluminum garnet activated by cerium" CRY018 "CRY019" lanthanum bromide and cadmium zinc telluride. We studied different properties of these crystals including density, energy resolution and decay times that are more important factors affecting the image quality. PMID:26420984

  17. Development of Scintillators in Nuclear Medicine

    OpenAIRE

    Khoshakhlagh, Mohammad; Islamian, Jalil Pirayesh; Abedi, Seyed Mohammad; Mahmoudian, Babak

    2015-01-01

    High-quality image is necessary for accurate diagnosis in nuclear medicine. There are many factors in creating a good image and detector is the most important one. In recent years, several detectors are studied to get a better picture. The aim of this paper is comparison of some type of these detectors such as thallium activated sodium iodide bismuth germinate cesium activated yttrium aluminum garnet (YAG: Ce) YAP: Ce “lutetium aluminum garnet activated by cerium” CRY018 “CRY019” lanthanum br...

  18. Radionuclides for routine diagnostics in nuclear medicine

    International Nuclear Information System (INIS)

    A survey is given on the radiopharmaceutics which are now in common use in nuclear medical diagnostics in vivo and in vitro. The development of radiopharmacology in the last 20 years has been characterized by the production of new and better radionuclides. A great step forward in clinical nuclear medicine has been the introduction of radionuclide generators for the production of short-lived nuclides. The most important and most generally used radionuclide for in vivo examinations is sup(99m)Tc pertechnetate. Tumour specific substances are still unknown, while the radioactive in vitro tests are of great clinical importance. They have opened up new possibilities of clinical laboratory diagnostics which are still not fully exploited. Special mention is made of the thyroid-specific in vitro tests in radiological thyroid diagnostics. (orig./AK)

  19. Quality management system in Nuclear Medicine

    International Nuclear Information System (INIS)

    Establishing Management Systems (QMS) in services Nuclear Medicine (NM) is a prerequisite for optimizing the efficacy and safety of diagnostic and therapeutic procedures of this specialty and increase steadily the quality of the services provide patients. Several international organizations such as the IAEA and scientific specialty societies (SNM, EBNM, etc) and national bodies stimulate and enhance their introduction; in our country is also a requirement of the National Nuclear Safety Centre (CNSN). Are presented in this paper, the main experiences of our country related to the implementation of QMS and developed tools for achieving this goal, such as: The QNUMED automated web environment for managing indicators and documentation format digital; b) The development of prototypes and models for the implementation of the documentation system; d) requirements applying QUANUM in conducting audits of quality management in local services including QUANUMTool tool; and f) human resource development issues in Quality Management. (author)

  20. Assessment of adherence to cardiovascular medicines in rural population: An observational study in patients attending a tertiary care hospital

    Directory of Open Access Journals (Sweden)

    Gouranga Santra

    2015-01-01

    Full Text Available Introduction: Nonadherence to cardiovascular medicines is a major concern. It increases the morbidity and mortality of cardiovascular patients. The work was conducted to evaluate the adherence to cardiovascular medicines in patients of rural India. Methods: The study was conducted in the Department of Medicine involving rural patients with essential hypertension (HTN, congestive cardiac failure (CCF, and ischemic heart disease (IHD over 12 months period. Patients were prescribed with cardiovascular medicines at the initial visit and adherence to medicines was assessed in the subsequent visit. Four items Morisky's Medication Adherence Scale (MMAS-4 was used for assessing medication adherence. Patients were considered adherent to medication if they answered negatively to all four questions. Results: Overall adherence to medication was 20.83%, 28.37% and 32% in HTN, CCF, and IHD patients, respectively. Nonadherence was highest in patients of HTN. Among the four reasons of nonadherence assessed by MMAS-4, carelessness was the most common and forgetfulness was the least common cause of nonadherence in all the three groups of patients. Conclusion: Patients of rural India adhere poorly to cardiovascular medicines. Nonadherence should be considered as a public health problem. Strategies for detecting the level of adherence of cardiovascular medicines, its barriers, and subsequent interventions should be developed by policy-makers to reduce morbidity and mortality due to cardiovascular disorders.

  1. Diagnostic nuclear medicine. 2. rev. ed.

    Energy Technology Data Exchange (ETDEWEB)

    Schiepers, C. (ed.) [UCLA David Geffen School of Medicine, Los Angeles, CA, (United States). Dept. of Molecular and Medical Pharmacology

    2006-07-01

    The field of nuclear medicine is undergoing rapid expansion, and is evolving into diagnostic molecular imaging. During recent years, dual-modality imaging with PET/CT has gained acceptance and this is currently the fastest-growing technique for oncological imaging applications. The glucose analogue FDG has held its place in diagnostic oncology, assessment of myocardial viability and diagnosis of neuro-degenerative disorders. Peptides have become even more important as imaging agents. The accuracy of hepatobiliary scintigraphy has been enhanced by cholecystokinin. The use of ACE inhibitors in the evaluation of renovascular hypertension has become the standard in renography. New instrumentation has led to faster scanners, and computer development to better image processing software. Automatic processing is more common, and standardization of protocols can be accomplished easily. The field of gene imaging has progressed, although routine clinical applications are not yet available. The present text, supplemented with many detailed and informative illustrations, represents an adjunct to the standard knowledge of diagnostic nuclear medicine and provides both the student and the professional with an overview of developments during the past decade. (orig.)

  2. Radiation dose assessment in nuclear medicine

    International Nuclear Information System (INIS)

    Radionuclides are used in nuclear medicine in a variety of diagnostic and therapeutic procedures. Recently, interest has grown in therapeutic agents for a number of applications in nuclear medicine. Internal dose models and methods have been in use for many years, are well established and can give radiation doses to stylized models representing reference individuals. Kinetic analyses need to be carefully planned, and dose conversion factors should be chosen that are most similar to the subject in question and that can then be tailored to be more patient specific. Such calculations, however, are currently not relevant in patient management in internal emitter therapy, as they are not sufficiently accurate or detailed to guide clinical decision making. Great strides are being made at many centres regarding the use of patient image data to construct individualized voxel based models for more detailed and patient specific dose calculations.These recent advances make it likely that the relevance will soon change to be more similar to that of external beam treatment planning. (author)

  3. Nuclear Medicine at Charles Sturt University

    International Nuclear Information System (INIS)

    Full text: A distance educational programme for upgrading of Certificate, Associate Diploma and Diploma to a Bachelor of Applied Science degree commenced in second semester of 1997 with approximately 15 Australian students and 15 Canadian students. The first graduation will occur in 1998. Formal links with the Michener Institute in Toronto have allowed Canadian students access to study resources during the course. All students entering the course are accredited or registered with their respective professional societies. The short conversion programme for those with three year diplomas includes Nuclear Medicine Physics and Instrumentation, Imaging Pathology, Clinical Neuroscience and Research Method subjects. An inaugural undergraduate degree programme in Nuclear Medicine Technology commences in first semester of 1998 on the Riverina Campus at Wagga Wagga. An intake of 15 students is anticipated. This small group of rural based students will have the benefits of international expertise. The programme has a strong clinical practice component including time on campus to supplement the practicum in departments. Physiology studies continue through to third year to complement the professional subjects. Active participation is solicited from those departments involved with aspects of the practicum well before students are placed. A fully functional teaching laboratory has been constructed containing a well equipped radiopharmacy, gamma camera room and computer laboratory using modern applications software to provide the students with a solid background in their chosen field

  4. The contribution of pulmonary nuclear medicine

    International Nuclear Information System (INIS)

    The contribution of pulmonary nuclear medicine was evaluated in 115 patients with interstitial pulmonary diseases (IPD). Ventilation study (V) with 81mKr or 133Xe, distribution of compliance in thoraco-pulmonary system (C) by 81mKr gas bolus inhalation method, perfusion study (Q) with 99mTc-MAA, 67Ga scintigraphy and an assessment of pulmonary epithelial permeability with 99mTc-DTPA aerosol were performed as nuclear medicine procedures. Pulmonary function test (%DLco, vital capacity, and functional residual capacity) and blood gas analysis were also examined. Abnormalities in V were larger than that in Q, which was high V/Q mismatch finding, in interstitial pneumonia. Correlation between V/Q mismatch and PaO2 was, therefore, not significant. %DLco was decreased in cases with larger V/Q mismatches. 67Ga accumulated in the early stage of interstitial pneumonia when CT or chest X-ray did not show any finding. %DLco was decreased in cases with strong accumulation of 67Ga. 67Ga might be useful to evaluate activity of the disease. Pulmonary epithelial permeability was assessed by 99mTc-DTPA inhalation study. This permeability became accelerated in idiopathic interstitial fibrosis and sarcoidosis. Pulmonary epithelial permeability may be useful as an indicator for epithelial cell injury. (author)

  5. Nuclear Medicine at Charles Sturt University

    Energy Technology Data Exchange (ETDEWEB)

    Swan, H. [Charles Sturt University, Wagga Wagga, NSW (Australia); Sinclair, P. [Charles Sturt University, Dubbo, NSW (Australia); Scollard, D. [Michener Institute, Toronto (Canada)

    1998-06-01

    Full text: A distance educational programme for upgrading of Certificate, Associate Diploma and Diploma to a Bachelor of Applied Science degree commenced in second semester of 1997 with approximately 15 Australian students and 15 Canadian students. The first graduation will occur in 1998. Formal links with the Michener Institute in Toronto have allowed Canadian students access to study resources during the course. All students entering the course are accredited or registered with their respective professional societies. The short conversion programme for those with three year diplomas includes Nuclear Medicine Physics and Instrumentation, Imaging Pathology, Clinical Neuroscience and Research Method subjects. An inaugural undergraduate degree programme in Nuclear Medicine Technology commences in first semester of 1998 on the Riverina Campus at Wagga Wagga. An intake of 15 students is anticipated. This small group of rural based students will have the benefits of international expertise. The programme has a strong clinical practice component including time on campus to supplement the practicum in departments. Physiology studies continue through to third year to complement the professional subjects. Active participation is solicited from those departments involved with aspects of the practicum well before students are placed. A fully functional teaching laboratory has been constructed containing a well equipped radiopharmacy, gamma camera room and computer laboratory using modern applications software to provide the students with a solid background in their chosen field

  6. Functional Measurements in Nuclear Medicine. Chapter 16

    International Nuclear Information System (INIS)

    The strength of nuclear medicine lies in using the tracer method to acquire information about how an organ is or is not functioning as it should. This modality, therefore, focuses on physiological organ function for diagnoses and not on anatomical information such as X ray computed tomography (CT) or magnetic resonance imaging. The three aspects involved in the process are: (i) choice of radioactive tracer, (ii) method of detection of the emissions from the tracer, and (iii) analysis of the results of the detection. The radioactive tracers on which nuclear medicine (or molecular imaging as it is increasingly being called) is based are designed to participate in or ‘trace’ a chosen function of the body. Their distribution is then found by detecting and locating the emissions, usually γ photons, of the radioactive tracer. The tracer may be involved in a metabolic process, such as iodine in the thyroid, or it may take part in a physiological process because of its physical make-up, such as macroaggregate of albumin (MAA) in the lungs

  7. Quality control of nuclear medicine instruments

    International Nuclear Information System (INIS)

    This document, which gives detailed guidance on the quality control of the various electronic instruments used for radiation detection and measurement in nuclear medicine, stems from the work of two Advisory Groups convened by the International Atomic Energy Agency (IAEA). A preliminary document, including recommended test schedules but lacking actual protocols for the tests, was drawn up by the first of these groups, meeting at the IAEA Headquarters in Vienna in 1979. A revised and extended version, incorporating recommended test protocols, was prepared by the second Group, meeting likewise in Vienna in 1982. This version is the model for the present text. The document should be of value to all nuclear medicine units, and especially to those in developing countries, in the initiation or revision of schemes for the quality control of their instruments. Its recommendations have provided the basis for instruction in two IAEA regional technical co-operation projects in the subject field, one initiated in 1981 for countries of Latin America and one initiated in 1982 for countries of Asia and the Pacific

  8. Redefining disease through advances in nuclear medicine

    International Nuclear Information System (INIS)

    Full text: Nuclear Imaging has progressed significantly in the last decade. The disease is being explored at receptor antigenic and biochemical level. The Molecular Imaging with tracers such as the 18-Fluro-Deoxy-Glucose (FDG), 11C-thymidine, 18-Fluro-Estradiol have enabled us to look into different aspects of disease. The FDG helps us in understanding aggressiveness of tumor and thereby survival of a cancer patient. It is enabling us to redefine disease at metabolic level leading to 'Metabolic Classification' of disease. The 18-Fluro-Estradiol scan is exploring breast cancer at receptor level and has enabled us to understand why some breast cancer patients do not respond to the hormone therapy. The 11C-Thymidine scan is able to image proliferative capacity of a tumor and thereby impact on the treatment approach. In addition to the field on oncology, recent advances in Nuclear Imaging are now providing valuable insights in understanding of various other human diseases. We are now redefining Alzheimer's disease and some of the psychiatric illnesses like Schizophrenia and Depression through the new Nuclear Imaging techniques. The years ahead will see extensive application of Nuclear Imaging technology in human disorders. Metabolic Classification of disease would bring out the processes underlying the causation and manifestation of diverse human disorders and help redefine the disease with the aim of more effective and less toxic personalized medicine

  9. The role of general nuclear medicine in breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    Greene, Lacey R, E-mail: lgreene@csu.edu.au [Faculty of Science, Charles Sturt University, Wagga Wagga, New South Wales (Australia); Wilkinson, Deborah [Faculty of Health, Wheeling Jesuit University, Wheeling, West Virginia (United States); Faculty of Science, Charles Sturt University, Wagga Wagga, New South Wales (Australia)

    2015-03-15

    The rising incidence of breast cancer worldwide has prompted many improvements to current care. Routine nuclear medicine is a major contributor to a full gamut of clinical studies such as early lesion detection and stratification; guiding, monitoring, and predicting response to therapy; and monitoring progression, recurrence or metastases. Developments in instrumentation such as the high-resolution dedicated breast device coupled with the diagnostic versatility of conventional cameras have reinserted nuclear medicine as a valuable tool in the broader clinical setting. This review outlines the role of general nuclear medicine, concluding that targeted radiopharmaceuticals and versatile instrumentation position nuclear medicine as a powerful modality for patients with breast cancer.

  10. The role of general nuclear medicine in breast cancer

    International Nuclear Information System (INIS)

    The rising incidence of breast cancer worldwide has prompted many improvements to current care. Routine nuclear medicine is a major contributor to a full gamut of clinical studies such as early lesion detection and stratification; guiding, monitoring, and predicting response to therapy; and monitoring progression, recurrence or metastases. Developments in instrumentation such as the high-resolution dedicated breast device coupled with the diagnostic versatility of conventional cameras have reinserted nuclear medicine as a valuable tool in the broader clinical setting. This review outlines the role of general nuclear medicine, concluding that targeted radiopharmaceuticals and versatile instrumentation position nuclear medicine as a powerful modality for patients with breast cancer

  11. History and Perspectives of Nuclear Medicine in Thailand

    Directory of Open Access Journals (Sweden)

    Sombut Boonyaprapa

    2014-10-01

    Full Text Available In 1955, the first nuclear medicine division was established in Thailand by Professor Romsai Suwannik in the Department of Radiology, Siriraj Hospil, Mahidol University in Bangkok. In 1959 four years later, the second nuclear medicine division was established in the Department of Radiology, Chulalongkorn Hospital in Bangkok. The third nuclear medicine division was started in Rajvithi Hospital in Bangkok in 1961. The fourth nuclear medicine division was installed in Chiang Mai University which is the first University located outside of Bangkok in 1965 by Professor Dusadee Prabhasavat and Professor Sanan Simarak, ten years after the first nuclear medicine division in Siriraj Hospital. At the present in Thailand, there are twenty-five organizations providing clinical nuclear medicine services. Five medical faculties provide three years nuclear medicine residency training. There are eight companies which supply radiopharmaceuticals and/or nuclear medicine instruments one of these belongs to governmental office of atomic for peace (OAP of Thailand. In conclusion: Nuclear medicine researches and clinical practices in Thailand had been progressed from the past to the present time and will more progress in the near future, which certainly is the part of Asian countries and ARCCNM.

  12. [Diet as a cardiovascular risk factor in family medicine].

    Science.gov (United States)

    Bergman Marković, Biserka; Katić, Milica; Vrdoljak, Davorka; Kranjcević, Ksenija; Jasna, Vucak; Ivezić Lalić, Dragica

    2010-05-01

    Although Mediterranean country by its geographic position, according to cardiovascular mortality (CVM) rate, Croatia belongs to Central-East European countries with high CV mortality. Prevention by changing nutritional habits is population (public health programmes) or individually targeted. General practitioner (GP) provides care for whole person in its environment and GP's team plays a key role in achieving lifestyle changes. GPs intervention is individually/group/family targeted by counselling or using printed leaflets (individual manner, organized programmes). Adherence to lifestyle changes is not an easy task; it is higher when recommendations are simple and part of individually tailored programme with follow- ups included. Motivation is essential, but obstacles to implementation (by patient and GPs) are also important. Nutritional intervention influences most important CV risk factors: cholesterol level, blood pressure (BP), diabetes. Restriction in total energy intake with additional nutritional interventions is recommended. Lower animal fat intake causes CVM reduction by 12%, taking additional serving of fruit/day by 7% and vegetables by 4%. Restriction of dietary salt intake (3 g/day) lowers BP by 2-8 mm Hg, CVM by 16%. Nutritional intervention gains CHD and stroke redact in healthy adults (12%, 11% respectively). Respecting individual lifestyle and nutrition, GP should suggest both home cooking and careful food declaration reading and discourage salt adding. Recommended daily salt intake is < or =6 g. In BP lowering, salt intake restriction (10-12 to 5-6 g/day) is as efficient as taking one antihypertensive drug. Lifestyle intervention targeting nutritional habits and pharmacotherapy is the most efficient combination in CV risk factors control. PMID:20649077

  13. Evaluation of radiation protection in nuclear medicine diagnostic procedures

    International Nuclear Information System (INIS)

    This study conducted to evaluate the radiation protection in nuclear medicine diagnostic procedures in four nuclear medicine departments in Sudan. The evaluated procedures followed in these departments were in accordance with the standards, International Recommendations and code of practice for radiation protection in nuclear medicine. The evolution included the optimum design for diagnostic nuclear medicine departments, dealing with radioactive sources, quality assurance and quality control, training and responsibilities for radiation worker taking into account economic factors in Sudan. Evaluation of radiation protection procedures in diagnostic investigations was carried out by taken direct measurements of dose rate and the contamination level in some areas where radiation sources, radiation workers and public are involved. Designated questionnaires covered thirteen areas of radiation protection based on inspection check list for nuclear medicine prepared by the International Atomic Energy Agency (IAEA) and American Association of Physicist in Medicine (AAPM) were used in the evaluation. This questionnaire has been Filled by Radiation Protection Officer (RPO), nuclear medicine technologist, nuclear medicine specialist in the nuclear medicine departments. Four hospitals, two governmental hospital and two private hospitals, have been assisted, the assessment shows that although the diagnostic nuclear medicine department in Sudan are not applying a fully safety and radiation protection procedures, but the level of radiation dose and the contamination level were found within acceptable limits. The private hospital D scored the higher level of protection (85.25%) while the governmental hospital C scored the lower level of protection (59.02%). Finally, this study stated some recommendations that if implemented could improve the level of radiation protection in nuclear medicine department. One of the most important recommendations is that a proper radiation protection

  14. Nuclear medicine achievements in Grenoble (France)

    International Nuclear Information System (INIS)

    The author reviews the contribution of the scientific teams of CENG (Grenoble nuclear research center) to nuclear medicine. CENG opened in 1958. At that time most research was dedicated to the understanding of the biological effects of radiation because of the cold war and its increased risk of nuclear disaster. In the sixties, the easy access to a broad range of artificial radio-nuclides, triggered the development of radio-pharmacology. Iodine-131 was used to study the thyroid gland, iron-59 and chromium-51 were used to study bone pathology and the kinetics of iron in the human body. Rubidium-86 and xenon-139 gave good results for the study of blood circulation. Iodine-123 and Krypton-81m were produced at the ISN cyclotron as soon as 1971. Around 1960 radiotherapy began to be performed in Grenoble specialized hospitals, where cobalt-60, iridium-192 and cesium-137 sources were intensively used. Today 3 teams worked on a project to adapt the proton emission tomograph that is due to be installed in a Grenoble hospital, to the study of the human brain. (A.C.)

  15. Analysis of renal nuclear medicine images

    International Nuclear Information System (INIS)

    Nuclear medicine imaging of the renal system involves producing time-sequential images showing the distribution of a radiopharmaceutical in the renal system. Producing numerical and graphical data from nuclear medicine studies requires defining regions of interest (ROIs) around various organs within the field of view, such as the left kidney, right kidney and bladder. Automating this process has several advantages: a saving of a clinician's time; enhanced objectivity and reproducibility. This thesis describes the design, implementation and assessment of an automatic ROI generation system. The performance of the system described in this work is assessed by comparing the results to those obtained using manual techniques. Since nuclear medicine images are inherently noisy, the sequence of images is reconstructed using the first few components of a principal components analysis in order to reduce the noise in the images. An image of the summed reconstructed sequence is then formed. This summed image is segmented by using an edge co-occurrence matrix as a feature space for simultaneously classifying regions and locating boundaries. Two methods for assigning the regions of a segmented image to organ class labels are assessed. The first method is based on using Dempster-Shafer theory to combine uncertain evidence from several sources into a single evidence; the second method makes use of a neural network classifier. The use of each technique in classifying the regions of a segmented image are assessed in separate experiments using 40 real patient-studies. A comparative assessment of the two techniques shows that the neural network produces more accurate region labels for the kidneys. The optimum neural system is determined experimentally. Results indicate that combining temporal and spatial information with a priori clinical knowledge produces reasonable ROIs. Consistency in the neural network assignment of regions is enhanced by taking account of the contextual

  16. Stereoscopic full aperture imaging in nuclear medicine

    Directory of Open Access Journals (Sweden)

    Sergio G. Strocovsky

    2011-06-01

    Full Text Available Images of planar scintigraphy and single photon emission computerized tomography (SPECT used in nuclear medicine are often low quality. They usually appear to be blurred and noisy. This problem is due to the low spatial resolution and poor sensitivity of the acquisition technique with the gamma camera (GC. Other techniques, such as coded aperture imaging (CAI reach higher spatial resolutions than GC. However, CAI is not frequently used for imaging in nuclear medicine, due to the decoding complexity of some images and the difficulty in controlling the noise magnitude. Summing up, the images obtained through GC are low quality and it is still difficult to implement CAI technique. A novel technique, full aperture Imaging (FAI, also uses gamma ray-encoding to obtain images, but the coding system and the method of images reconstruction are simpler than those used in CAI. In addition, FAI also reaches higher spatial resolution than GC. In this work, the principles of FAI technique and the method of images reconstruction are explained in detail. The FAI technique is tested by means of Monte Carlo simulations with filiform and spherical sources. Spatial resolution tests of GC versus FAI were performed using two different source-detector distances. First, simulations were made without interposing any material between the sources and the detector. Then, other more realistic simulations were made. In these, the sources were placed in the centre of a rectangular prismatic region, filled with water. A rigorous comparison was made between GC and FAI images of the linear filiform sources, by means of two methods: mean fluence profile graphs and correlation tests. Finally, three-dimensional capacity of FAI was tested with two spherical sources. The results show that FAI technique has greater sensitivity (>100 times and greater spatial resolution (>2.6 times than that of GC with LEHR collimator, in both cases, with and without attenuating material and long and

  17. Aspects on caring in pediatric nuclear medicine

    International Nuclear Information System (INIS)

    During nuclear medicine examinations, the child is exposed to more or less distressful and/or painful procedures. Many children find it difficult to understand why they have to go through a specific examination. In addition, the surrounding is unfamiliar with heavy technical equipment. The first experience is crucial for the child's future attitudes towards hospitals in general and diagnostic procedures in particular. Apart from having child-focused personnel, there are many ways to improve the situation, and I will focus on four corner-stones. 1. Information; 2. Pain relief; 3. Diversion; 4. Sedation. 1. Information should be addressed directly to the child as well as to the parents. Today, children use the computer already from an early age, and we have initiated the use of Internet as a medium for child-adapted information. With texts, photos and multimedia on an interactive site we are able to reach also quite young children as well as children with difficulties to understand only written parts. Pain relief for vein puncture should always be considered. We use the topical anaesthetic EMLA cream in newborns (> 2.800 g) as well as in teenagers. Trained staff is another condition for high success rate in performing vein punctures, and continuous education vouches for that. 3. Diversion (distraction) is a general term for directing the child's attention from the procedures or to make time pass faster. Age adapted diversions should be readily available for every child. Apart from soap bubbles, toys, books, music and videos there are other possibilities, such as 'Guided imagery', a way of day-dreaming initiated by personnel trained in this method. 4. Sedation should be used when other options are not sufficient. For conscious sedation we use midazolam, administered either iv, intranasal, rectally or orally. The nurses/technologists handle the routines. In nuclear medicine, 4-5 % of the children, mostly between 1-3 years old, are sedated either for fear of vein

  18. Generation and Assessment of Functional Biomaterial Scaffolds for Applications in Cardiovascular Tissue Engineering and Regenerative Medicine

    OpenAIRE

    Hinderer, Svenja; Brauchle, Eva; Schenke‐Layland, Katja

    2015-01-01

    Current clinically applicable tissue and organ replacement therapies are limited in the field of cardiovascular regenerative medicine. The available options do not regenerate damaged tissues and organs, and, in the majority of the cases, show insufficient restoration of tissue function. To date, anticoagulant drug‐free heart valve replacements or growing valves for pediatric patients, hemocompatible and thrombus‐free vascular substitutes that are smaller than 6 mm, and stem cell‐recruiting de...

  19. Draft report on the national seminar in nuclear medicine

    International Nuclear Information System (INIS)

    The proceedings of the seminar on nuclear medicine have been conducted in four main sessions. In the first session a review of the current status of clinical nuclear medicine in India is reviewed. The use of radioisotopes in thyroid function studies, central nervous systems, liver disorders, lung and bone imaging, renal function studies, dynamic function studies, gastroenterology haematology etc. are described. The existing facilities and the future needs for radioimmunoassay and radiotherapy are discussed. In Session 2, the existing facilities in nuclear medicine in different states in India are reviewed. In Session 3, the available resources in nuclear medicine are reviewed. Radiation protection procedures are outlined. Various nuclear instruments developed at the Bhabha Atomic Research Centre, (BARC), Bombay, for use in nuclear medicine are briefly described. A list of radiopharmaceuticals developed by BARC and in current use, is given. The roles of the physicist, pharmacist and the nuclear medicine technologist in the hospitals having nuclear medicine units, are stressed. The importance of training and education for personnel in nuclear medicine and medical physics is pointed out. (A.K.)

  20. The impact of nuclear science on medicine

    CERN Document Server

    Kraft, G

    1999-01-01

    From the very beginning, i.e. from the discovery of the natural radioactivity by H. Becquerel and the production of radium by M. Curie, nuclear physics had a strong impact on medicine: Radioactive sources were immediately made use of in tumor therapy long before the action mechanisms of ionizing radiation were understood. The invention of the tracer technique by G. Hevesy opened a new field for the study of chemokinetics as well as for the in-vivo measurement of various organ functions. In the percutane tumor therapy hadrons like neutrons, pions, protons and heavier ions were tested. Presently, proton therapy is a great success and is spreading all over the world. The new techniques of target-conform treatment using heavy ions for an improved tumor targeting and control represent the latest great improvement of radiation tumor therapy.

  1. What is generally meant by nuclear medicine

    International Nuclear Information System (INIS)

    The work field of nuclear medicine students are defined and include 'in vivo' and 'in vitro' radioactive isotopes research, radio-therapy, radio-pharmacology, and the study of irradiation effects. Therapy treatments detailed include applications to hyperthyroids, thyroid cancer and polycythaemia. Definitions are also given of the radioactive half-lives of radionuclides, both physical and biological, used in medical research. Details are given of the relatively new technique of radioactive generators, sometimes known as 'radioactive cows', of which 99m Tc is widely used at present as its half-life (6 hours) is suitable for medical work. Tabular information is given for radio-pharmaceuticals with special relevance to specific organs of the body, e.g. thyroid, kidney, lung, pancreas, etc. (G.C.)

  2. Directory of computer users in nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Henne, R.L.; Erickson, J.J.; McClain, W.J.; Kirch, D.L.

    1977-01-01

    The directory is composed of two major divisions, a Users' section and a Vendors' section. The Users' section consists of detailed installation descriptions and indexes to these descriptions. A typical description contains the name, address, type, and size of the institution as well as names of persons to contact. Following the hardware descriptions are listed the type of studies for which the computers are utilized, including the languages used, the method of output and an estimate of how often the study is performed. The Vendors' section contains short descriptions of current commercially available nuclear medicine systems as supplied by the vendors themselves. In order to reduce the amount of obsolete data and to include new institutions in future updates of the directory, a user questionnaire is included. (HLW)

  3. Directory of computer users in nuclear medicine

    International Nuclear Information System (INIS)

    The directory is composed of two major divisions, a Users' section and a Vendors' section. The Users' section consists of detailed installation descriptions and indexes to these descriptions. A typical description contains the name, address, type, and size of the institution as well as names of persons to contact. Following the hardware descriptions are listed the type of studies for which the computers are utilized, including the languages used, the method of output and an estimate of how often the study is performed. The Vendors' section contains short descriptions of current commercially available nuclear medicine systems as supplied by the vendors themselves. In order to reduce the amount of obsolete data and to include new institutions in future updates of the directory, a user questionnaire is included

  4. Pathogenesis and role of nuclear medicine

    International Nuclear Information System (INIS)

    The means by which replication of viruses takes place is explained, as it helps in the understanding of how viruses spread in the blood and how antiretroviral drugs work. The most important viruses, from a health care workers point of view, are hepatitis B and C and human immunodefiency virus (HIV). Whether nuclear medicine has a role to play in the diagnosis of these viruses, and the oportunistic infections that go with them, is debatable. Several radiopharmaceuticals are extremely sensitive for infection and tumor imaging but lack specificity. Patients' treatment is often not based on the outcome of the investigation but rather on preset protocols. AIDS patients are put on prophylactic antibiotic treatment as protection against infections such as toxoplasmosis and pneumocystis carinii pneumonia and there is a poor prognosis for AIDS patients with tumors (Au)

  5. Emerging applications of radioisotopes in nuclear medicine

    International Nuclear Information System (INIS)

    Advances in the domain of radioisotopes and radiopharmaceuticals has been very noteworthy over the past decade and played a major role in enhancing the Nuclear Medicine practice. A number of them have been employed in the day to day clinical practice and have benefited a large number of patients. For the purpose of systematic discussion, we shall classify into two major heads A. Recent advances in clinical applications of traditional radiotracers. B. Newer Radiopharmaceuticals and their applications. The latter could be further subdivided in to the following: (a) Diagnostic (includes i. PET radiopharmaceuticals and ii. Non-PET radiopharmaceuticals for conventional gamma camera imaging) and (b) Therapeutic advances. In the present communication, we shall explore the major developments emphasizing the country perspective

  6. Nuclear medicine training and practice in the Czech Republic.

    Science.gov (United States)

    Kamínek, Milan; Koranda, Pavel

    2014-08-01

    Nuclear medicine in the Czech Republic is a full specialty with an exclusive practice. Since the training program was organized and structured in recent years, residents have had access to the specialty of nuclear medicine, starting with a two-year general internship (in internal medicine or radiology). At present, nuclear medicine services are provided in 45 departments. In total, 119 nuclear medicine specialists are currently registered. In order to obtain the title of Nuclear Medicine Specialist, five years of training are necessary; the first two years consist of a general internship in internal medicine or radiology. The remaining three years consist of training in the nuclear medicine specialty itself, but includes three months of practice in radiology. Twenty-one physicians are currently in nuclear medicine training and a mean of three specialists pass the final exam per year. The syllabus is very similar to that of the European Union of Medical Specialists (UEMS), namely concerning the minimum recommended numbers for diagnostic and therapeutic procedures. In principle, the Czech law requires continuous medical education for all practicing doctors. The Czech Medical Chamber has provided a continuing medical education (CME) system. Other national CMEs are not accepted in Czech Republic. PMID:24867257

  7. Nuclear medicine training and practice in the Czech Republic

    Energy Technology Data Exchange (ETDEWEB)

    Kaminek, Milan; Koranda, Pavel [University Hospital Olomouc, Department of Nuclear Medicine, Olomouc (Czech Republic)

    2014-08-15

    Nuclear medicine in the Czech Republic is a full specialty with an exclusive practice. Since the training program was organized and structured in recent years, residents have had access to the specialty of nuclear medicine, starting with a two-year general internship (in internal medicine or radiology). At present, nuclear medicine services are provided in 45 departments. In total, 119 nuclear medicine specialists are currently registered. In order to obtain the title of Nuclear Medicine Specialist, five years of training are necessary; the first two years consist of a general internship in internal medicine or radiology. The remaining three years consist of training in the nuclear medicine specialty itself, but includes three months of practice in radiology. Twenty-one physicians are currently in nuclear medicine training and a mean of three specialists pass the final exam per year. The syllabus is very similar to that of the European Union of Medical Specialists (UEMS), namely concerning the minimum recommended numbers for diagnostic and therapeutic procedures. In principle, the Czech law requires continuous medical education for all practicing doctors. The Czech Medical Chamber has provided a continuing medical education (CME) system. Other national CMEs are not accepted in Czech Republic. (orig.)

  8. Nuclear medicine training and practice in the Czech Republic

    International Nuclear Information System (INIS)

    Nuclear medicine in the Czech Republic is a full specialty with an exclusive practice. Since the training program was organized and structured in recent years, residents have had access to the specialty of nuclear medicine, starting with a two-year general internship (in internal medicine or radiology). At present, nuclear medicine services are provided in 45 departments. In total, 119 nuclear medicine specialists are currently registered. In order to obtain the title of Nuclear Medicine Specialist, five years of training are necessary; the first two years consist of a general internship in internal medicine or radiology. The remaining three years consist of training in the nuclear medicine specialty itself, but includes three months of practice in radiology. Twenty-one physicians are currently in nuclear medicine training and a mean of three specialists pass the final exam per year. The syllabus is very similar to that of the European Union of Medical Specialists (UEMS), namely concerning the minimum recommended numbers for diagnostic and therapeutic procedures. In principle, the Czech law requires continuous medical education for all practicing doctors. The Czech Medical Chamber has provided a continuing medical education (CME) system. Other national CMEs are not accepted in Czech Republic. (orig.)

  9. Cellular dosimetry in nuclear medicine imaging: training

    International Nuclear Information System (INIS)

    The radionuclides used in nuclear medicine imaging emit not only diagnostically useful photons, but also energy electron emissions, responsible for dose heterogeneity at the cellular level. The mean dose delivered to the cell nucleus by electron emissions of 99mTc, 123I, 111In, 67Ga, and 201Tl, has been calculated, for the cell nucleus, a cytoplasmic and a cell membrane distribution of radioactivity. This model takes into account both the self-dose which results from the radionuclide located in the target cell, and the cross-dose, which comes from the surrounding cells. The results obtained by cellular dosimetry (Dcel) have been compared with those obtained with conventional dosimetry (Dconv), by assuming the same amount of radioactivity per cell. Cellular dosimetry shows, for a cytoplasmic and a cell membrane distributions of radioactivity, that the main contribution to the dose to the cell nucleus, comes from the surrounding cells. On the other hand, for a cell nucleus distribution of radioactivity, the self-dose is not negligible and may be the main contribution. The comparison between cellular and conventional dosimetry shows that Dcel/Dconv ratio ranges from 0.61 and O.89, in case of a cytoplasmic and a cell membrane distributions of radioactivity, depending on the radionuclide and cell dimensions. Thus, conventional dosimetry slightly overestimates the mean dose to the cell nucleus. On the other hand, Dcel/Dconv ranges from 1.1 to 75, in case of a cell nucleus distribution of radioactivity. Conventional dosimetry may strongly underestimates the absorbed dose to the nucleus, when radioactivity is located in the nucleus. The study indicates that in nuclear medicine imaging, cellular dosimetry may lead to a better understanding of biological effects of radiopharmaceuticals. (authors)

  10. Display of nuclear medicine imaging studies

    International Nuclear Information System (INIS)

    Nuclear medicine imaging studies involve evaluation of a large amount of image data. Digital signal processing techniques have introduced processing algorithms that increase the information content of the display. Nuclear medicine imaging studies require interactive selection of suitable form of display and pre-display processing. Static imaging study requires pre-display processing to detect focal defects. Point operations (histogram modification) along with zoom and capability to display more than one image in one screen is essential. This album mode of display is also applicable to dynamic, MUGA and SPECT data. Isometric display or 3-D graph of the image data is helpful in some cases e.g. point spread function, flood field data. Cine display is used on a sequence of images e.g. dynamic, MUGA and SPECT imaging studies -to assess the spatial movement of tracer with time. Following methods are used at the investigator's discretion for inspection of the 3-D object. 1) Display of orthogonal projections, 2) Display of album of user selected coronal/ sagital/ transverse orthogonal slices, 3) Display of three orthogonal slices through user selected point, 4) Display of a set of orthogonal slices generated in the user-selected volume, 5) Generation and display of 3-D shaded surface. 6) Generation of volume data and display along with the 3-D shaded surface, 7) Side by side display orthogonal slices of two 3-D objects. Displaying a set of two-dimensional slices of a 3-D reconstructed object through shows all the defects but lacks the 3-D perspective. Display of shaded surface lacks the ability to show the embedded defects. Volume display -combining the 3-D surface and gray level volume data is perhaps the best form of display. This report describes these forms of display along with the theory. (author)

  11. Practice of nuclear medicine in a developing country

    International Nuclear Information System (INIS)

    For more than a half a century nuclear medicine is contributing in the field of medicine. Still nuclear medicine is not widely available in many countries. Especially in developing countries due to many a reasons nuclear medicine could not flourish in that way. Availability of radioisotope, high cost of instrument and sophistication of the branch are the three main reasons behind. Even the countries where nuclear medicine is functioning for quite a long time, the facilities for proper function are still not adequate. Training of manpower, maintenance of instruments, regular supply of isotopes and kit and cost effectiveness are some of the major problems. We have seen some fast developments in nuclear medicine in last few decades. Development of gamma detecting systems with SPECT, positron emission detector (PET), supported computer technology and introduction of some newer radiopharmaceuticals for functional studies are few of the examples. The developing countries also have a problem to go on parallel with these rapid development of nuclear medicine in other part of the world. In last few decades we have also witnessed development of CT, MRI, Ultrasound and other imaging modalities as our competitor. Specially for developing countries these have posed as a major challenge for nuclear medicine. A better understanding between developed and developing nations is the key point of todays ultimate success in any sector. For real development of nuclear medicine and to give the majority of the people the benefit of nuclear medicine a better and more active co-operation is needed between all the countries. The paper presents the difficulties and some practical problems of practicing nuclear medicine in a developing country. And also appeals for global co-operation to solve the problems for better interest of the subject

  12. The state of the art in diagnostic nuclear medicine

    International Nuclear Information System (INIS)

    Recent improvements in the understanding of the physiologic and biologic mechanisms of health and disease have led to an expansion of nuclear medicine applications both in clinical studies and research. Advances in radiopharmaceutical development, instrumentation and computer processing have resulted in the implementation of Positron Emission Tomography for clinical studies, and improved treatments with radiopharmaceuticals particularly in cancer patients. There has also been an dramatic increase in the techniques available with nuclear medicine to detect and measure cellular biologic events in-vivo, which have important implications in clinical and basic science research. Nuclear medicine studies provide unique information on human physiology and remain an integral part of clinical medicine practice

  13. The state of the art in nuclear medicine

    International Nuclear Information System (INIS)

    Recent improvements in the understanding of the physiologic and biologic mechanisms of health and disease have led to an expansion of nuclear medicine applications both in clinical studies and research. Advances in radiopharmaceutical development, instrumentation and computer processing have resulted in the implementation of Positron Emission Tomography for clinical studies, and improved treatments with radiopharmaceuticals particularly in cancer patients. There has also been a dramatic increase in the techniques available with nuclear medicine to detect and measure cellular biologic events in-vivo, which have important implications in clinical and basic science research. Nuclear medicine studies provide unique information on human physiology and remain an integral part of clinical medicine practice

  14. Proceedings of the Korean Society Nuclear Medicine Spring Meeting 1999

    International Nuclear Information System (INIS)

    This proceedings contains articles of 1999 spring meeting of the Korean Society Nuclear Medicine. It was held on May 21, 1999 in Chonju, Korea. The subject title of proceedings is radioisotope therapy using Re-188. Radiopharmaceuticals have been used for the diagnosis and treatment of human diseases, mostly for the diagnostic purposes in nuclear medicine. (Yi, J. H.)

  15. Management of radioactive waste generated in nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine is a clinical specialty in which radioactive material is used in non-encapsulated form, for the diagnosis and treatment of patients. Nuclear medicine involves administering to a patient a radioactive substance, usually liquid, both diagnostic and therapeutic purposes. This process generates solid radioactive waste (syringes, vials, gloves) and liquid (mainly the patient's urine). (Author)

  16. Nuclear medicine and articulation prosthesis of the lower limbs

    International Nuclear Information System (INIS)

    Several nuclear medicine procedures can help the surgeons in the diagnosis of the complications of articulations prosthesis of the lower limbs, in particular in case of torpid infection. Even if the diagnosis remains uncertain, the indications and the interpretation of these procedures benefit of a close collaboration between nuclear medicine specialist and clinicians. (author)

  17. Nuclear medicine and its radiological protection in China

    International Nuclear Information System (INIS)

    The China Society of Nuclear Medicine was established on 27 May 1980. Since then, nuclear medicine in clinical diagnosis and therapy has been developed rapidly in China. So far there are more than 4000 members of the Society, and more than 350 sets of SPECT and 12 sets of PET have been installed and are busily running in clinic nowadays and about 1 million patients with different types of diseases have obtained nuclear medicine imaging examinations per year. Concerning the nuclear medicine therapy, a lot of patients with many types of diseases obtained benefit from radioisotope therapy. Accordingly, several Policies and Regulations have been enacted by the Government for the radiological protection. Furthermore, a special book titled 'Standardization in Diagnostic and Therapeutic Nuclear Medicine' has been promulgated in June, 1997 by the Health Administration of People's Republic of China, and this book is distributed to almost every nuclear medicine physician and technician in China for their reference in routine nuclear medicine work or research. In this book three parts of the contents are covered: Policies and Regulations for the radiological protection, basic knowledge and clinical nuclear medicine applications. (author)

  18. Source Book of Educational Materials for Nuclear Medicine.

    Science.gov (United States)

    Pijar, Mary Lou, Comp.; Lewis, Jeannine T., Comp.

    The contents of this sourcebook of educational materials are divided into the following sections: Anatomy and Physiology; Medical Terminology; Medical Ethics and Department Management; Patient Care and Medical Decision-Making; Basic Nuclear Medicine; Diagnostic in Vivo; Diagnostic in Vitro; Pediatric Nuclear Medicine; Radiation Detection and…

  19. Career prospects for graduating nuclear medicine residents: survey of nuclear medicine program directors.

    Science.gov (United States)

    Harolds, Jay A; Guiberteau, Milton J; Metter, Darlene F; Oates, M Elizabeth

    2013-08-01

    There has been much consternation in the nuclear medicine (NM) community in recent years regarding the difficulty many NM graduates experience in securing initial employment. A survey designed to determine the extent and root causes behind the paucity of career opportunities was sent to all 2010-2011 NM residency program directors. The results of that survey and its implications for NM trainees and the profession are presented and discussed in this article. PMID:23763875

  20. Nuclear medicine - the state of the art of nuclear medicine in Europe

    International Nuclear Information System (INIS)

    The present proceedings of the European Nuclear Medicine Congress 1990 contain the opening addresses and the oral presentations of the meeting. The topics were as follows: Methods and basics (52 papers), cardiology (12 papers), neurology (13 papers), pulmonology (2 papers), gastroenterology (9 papers), nephrology (7 papers), osteology (8 papers), endocrinology (7 papers), pediatrics (5 papers), and oncology (12 papers). An author index and a subject index is found as a supplement to these proceedings. (MG) With 182 figs., 92 tabs

  1. Current Status of The Korean Society of Nuclear Medicine

    International Nuclear Information System (INIS)

    As the application of nuclear medicine to clinics became generalized and it held an important position, the Korean Society of Nuclear Medicine was founded in 1961, and today it has become known as one of the oldest nuclear medicine societies not only to Asian nations but also to other advanced countries all over the world. Now it has 100 or so regular members composed of students of each medicine filed unlike other medical societies. Only nuclear medicine research workers are eligible for its membership. The Korean Society of Nuclear Medicine holds its regular general meeting and symposium twice per annom respectively in addition to occasional group gatherings and provincial lectures on nuclear medicine. With an eye to exchanging information on symposium, research and know-how, KSNM issued its initial magazine in 1967. Every year two editions are published. Year after year the contents of treatises are getting elevated with researches on each field including the early study on morphology-greatly improved both in quality and quantity. Of late, a minute and fixed quantity of various matters by dynamical research and radioimmunoassay of every kind has become visibly active. In particular, since KSNM, unlike other local societies, keeps close and frequent contact with the nuclear medicine researchers of world-wide fame, monographs by eminent scholars of the world are carried in its magazine now internationally and well received in foreign countries. Now the magazine has been improved to such an extent that foreign authors quote its contents. KSNM invited many a foreign scholar with a view to exchanging the knowledge of nuclear medicine. Sponsored by nuclear energy institute, the nuclear medicine symposium held in Seoul in October of 1966 was a success with Dr. Wagner participating, a great scholar of world wide fame: It was the first international symposium ever held in Korea, and the Korea Japan symposium held in Seoul 1971 was attended by all distinguished nuclear

  2. Critical appraisal of diagnostic studies in nuclear medicine

    International Nuclear Information System (INIS)

    The conceptual ideas of evidence based critical appraisal of diagnostic studies are described in this survey. In this context special attention is given to biases in study design such as verification- as well as information-bias limiting the validity of diagnostic studies. The practice of critical appraisal is demonstrated in an application to an example of a nuclear medicine scenario. The impact of evidence based medicine on nuclear medicine as a diagnostic discipline is discussed in detail. (orig.)

  3. Pulmonary nuclear medicine: Techniques in diagnosis of lung disease

    International Nuclear Information System (INIS)

    This book presents papers on the application of nuclear medicine to the diagnosis of lung diseases. Topics considered include lung physiology and anatomy, radiopharmaceuticals in pulmonary medicine, pulmonary embolism, obstructive pulmonary disease, diffuse infiltrative lung disease, pneumoconioses, tumor localization scans in primary lung tumors, the interactions of heart diseases and lung diseases on radionuclide tests of lung anatomy and function, radionuclide imaging in pediatric lung diseases, and future possibilities in pulmonary nuclear medicine

  4. Nuclear medicine. Basic knowledge and clinical applications. 7. rev. and enl. ed.; Nuklearmedizin. Basiswissen und klinische Anwendung

    Energy Technology Data Exchange (ETDEWEB)

    Schicha, Harald [Universitaetsklinikum Koeln (Germany). Medizinisches Versorgungszentrum II; Schober, Otmar [Universitaetsklinikum Muenster (Germany). Klinik fuer Nuklearmedizin

    2013-11-01

    The book on basic knowledge and clinical applications of nuclear medicine covers the following issues: The first general part: principles of nuclear medicine; physical fundamentals; radiopharmaceutical chemistry; measuring techniques: gamma detectors, gamma spectrometry, gamma camera, SPECT, PET, PET/CT, PET/NMR, image processing and communication; nuclear medical examinations: metabolic and pharmacological kinetics, scintigraphic methods, criteria for the use; quality assurance; dosimetry and radiation protection, radiation risks and patients exposure, benefit-risk considerations. The second part covers endocrine organs, carcinomas, skeleton and bone joints, inflammations, lymph system, cardiovascular system, lungs, central nervous system, kidneys and urinary system, gastrointestinal tract, other scintigraphic examinations.

  5. Quality Management Audits in Nuclear Medicine Practices. 2. Ed

    International Nuclear Information System (INIS)

    Quality management systems are essential and should be maintained with the intent to continuously improve effectiveness and efficiency, enabling nuclear medicine to achieve the expectations of its quality policy, satisfy its customers and improve professionalism. The quality management (QM) audit methodology in nuclear medicine practice, introduced in this publication, is designed to be applied to a variety of economic circumstances. A key outcome is a culture of reviewing all processes of the clinical service for continuous improvement in nuclear medicine practice. Regular quality audits and assessments are vital for modern nuclear medicine services. More importantly, the entire QM and audit process has to be systematic, patient oriented and outcome based. The management of services should also take into account the diversity of nuclear medicine services around the world and multidisciplinary contributions. The latter include clinical, technical, radiopharmaceutical, medical physics and radiation safety procedures

  6. Assessing and Reducing Exposures to Nuclear Medicine Staff

    International Nuclear Information System (INIS)

    Nuclear medicine involves the handling of unsealed radiation sources. Occupational monitoring in nuclear medicine, thus, includes assessment of both external irradiation of the body and internal exposure due to inhalation or ingestion of radioactive substances. When appropriate radiation protection measures are applied, the annual effective dose to nuclear medicine staff is low (around 2–3 mSv). However, hand doses can be very high and can even exceed the regulatory limit for skin equivalent dose, without workers being aware of it. The paper presents the main results of the European Atomic Energy Community’s Seventh Framework Programme project, Optimization of Radiation Protection of Medical Staff (ORAMED), within the field of extremity dosimetry of nuclear medicine staff, and proposes recommendations to improve radiation protection in occupational exposure in nuclear medicine. (author)

  7. Japanese consensus guidelines for pediatric nuclear medicine. Part 1. Pediatric radiopharmaceutical administered doses (JSNM pediatric dosage card). Part 2. Technical considerations for pediatric nuclear medicine imaging procedures

    International Nuclear Information System (INIS)

    The Japanese Society of Nuclear Medicine has recently published the consensus guidelines for pediatric nuclear medicine. This article is the English version of the guidelines. Part 1 proposes the dose optimization in pediatric nuclear medicine studies. Part 2 comprehensively discusses imaging techniques for the appropriate conduct of pediatric nuclear medicine procedures, considering the characteristics of imaging in children. (author)

  8. Scintigraphic instruments and techniques in nuclear medicine

    International Nuclear Information System (INIS)

    The development of new radiopharmaceuticals, cyclotron-produced radionuclides and improvement of detector, scanner and gamma camera characteristics have enable a remarkable recent progress in scintigraphic techniques for organ visualization and functional studies. Using a variety of techniques, positron cameras, section scanners, gamma holography, tomographic imaging appear to be playing an increasing important role. Data processing techniques, for example image processing and three dimensional reconstruction have significantly increased their impact. The principal research work and advances in technique achieved up to 1972 are summarized and the subjects which have been further exploited are outlined. The main section comprises references and abstracts of articles from scientific journals and conference proceedings (191 articles and 221 papers mentioned) for the period 1972-1975 to illustrate advances in this domain: Excerpta Medica (Nuclear Medicine) Abstract Journals and Nuclear Science Abstracts (1972-1975) were used as abstracting publications. This survey is completed with an index of authors and subject-matters. Eleven thesis are mentionned in an appendix

  9. Instrumentation and procedural problems in nuclear medicine

    International Nuclear Information System (INIS)

    In this chapter, the nuclear instrumentation problems, procedural errors, and resultant scintiphoto artifacts that might be encountered before, during, and after a nuclear medicine scan are discussed. In practice, whenever a scintiphoto is of unacceptable quality or contains an evident artifact, it generally is discarded, corrective actions are taken and, if possible the study is repeated. Instead of discarding the unacceptable scan, however, a notebook of all of these imaging artifacts could be compiled and made accessible to all personnel in the department. This artifact identification notebook is especially useful in a teaching institution in which technologists or residents are being trained. There is no better learning axion than that ''you learn by your mistakes.'' It is much easier on a department for rookies to learn from the mistakes of others, as cited in the artifact notebook, than for each individual to repeat all the common mistakes made by those who came before. It also becomes easier to identify or recognize the cause of many artifacts by referencing the manual or notebook

  10. New nuclear medicine gamma camera systems

    International Nuclear Information System (INIS)

    The acquisition of the Open E.CAM and DIACAM gamma cameras by Makati Medical Center is expected to enhance the capabilities of its nuclear medicine facilities. When used as an aid to diagnosis, nuclear medicine entails the introduction of a minute amount of radioactive material into the patient; thus, no reaction or side-effect is expected. When it reaches the particular target organ, depending on the radiopharmaceutical, a lesion will appear as a decrease (cold) area or increase (hot) area in the radioactive distribution as recorded byu the gamma cameras. Gamma camera images in slices or SPECT (Single Photon Emission Computer Tomography), increase the sensitivity and accuracy in detecting smaller and deeply seated lesions, which otherwise may not be detected in the regular single planar images. Due to the 'open' design of the equipment, claustrophobic patients will no longer feel enclosed during the procedure. These new gamma cameras yield improved resolution and superb image quality, and the higher photon sensitivity shortens imaging acquisition time. The E.CAM, which is the latest generation gamma camera, is featured by its variable angle dual-head system, the only one available in the Philipines, and the excellent choice for Myocardial Perfusion Imaging (MPI). From the usual 45 minutes, the acquisition time for gated SPECT imaging of the heart has now been remarkably reduced to 12 minutes. 'Gated' infers snap-shots of the heart in selected phases of its contraction and relaxation as triggered by ECG. The DIACAM is installed in a room with access outside the main entrance of the department, intended specially for bed-borne patients. Both systems are equipped with a network of high performance Macintosh ICOND acquisition and processing computers. Added to the hardware is the ICON processing software which allows total simultaneous acquisition and processing capabilities in the same operator's terminal. Video film and color printers are also provided. Together

  11. The practice of nuclear medicine in the Philippines

    International Nuclear Information System (INIS)

    The advent of nuclear medicine in the early 1940's came with the use of radioiodine in the study of thyroid physiology and eventual treatment of hyperthyroidism. Instrumentation to detect radionuclides introduced into the human body, and the production of various radiopharmaceuticals as tracers or as therapy agents provided the impetus for the rapid development of nuclear medicine as a distinct specialty. In the Philippines, nuclear medicine formally began in 1956 with the establishment of the Radioisotope Laboratory at the Philippine General Hospital. Acquisition of nuclear instrumentation by various institutions, training of medical staff and personnel, sourcing of radiopharmaceuticals proceeded thereafter

  12. Heart rate control with adrenergic blockade: Clinical outcomes in cardiovascular medicine

    Directory of Open Access Journals (Sweden)

    David Feldman

    2010-05-01

    Full Text Available David Feldman1, Terry S Elton2, Doron M Menachemi3, Randy K Wexler41Heart Failure/Transplant and VAD Programs, Minneapolis Heart Institute, Minneapolis, Minnesota, USA; 2Division of Pharmacology, College of Pharmacology, The Ohio State University, Columbus, Ohio, USA; 3Heart Failure Services, Edith Wolfson Medical Center, The Heart Institute, Sakler School of Medicine, Tel-Aviv University, Holon, Israel; 4Department of Clinical Family Medicine, The Ohio State University, Columbus, Ohio, USAAbstract: The sympathetic nervous system is involved in regulating various cardiovascular parameters including heart rate (HR and HR variability. Aberrant sympathetic nervous system expression may result in elevated HR or decreased HR variability, and both are independent risk factors for development of cardiovascular disease, including heart failure, myocardial infarction, and hypertension. Epidemiologic studies have established that impaired HR control is linked to increased cardiovascular morbidity and mortality. One successful way of decreasing HR and cardiovascular mortality has been by utilizing β-blockers, because their ability to alter cell signaling at the receptor level has been shown to mitigate the pathogenic effects of sympathetic nervous system hyperactivation. Numerous clinical studies have demonstrated that β-blocker-mediated HR control improvements are associated with decreased mortality in postinfarct and heart failure patients. Although improved HR control benefits have yet to be established in hypertension, both traditional and vasodilating β-blockers exert positive HR control effects in this patient population. However, differences exist between traditional and vasodilating β-blockers; the latter reduce peripheral vascular resistance and exert neutral or positive effects on important metabolic parameters. Clinical evidence suggests that attainment of HR control is an important treatment objective for patients with cardiovascular

  13. Special monitoring in nuclear medicine; Monitoreo especial en medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Beltran, C.C.; Puerta, J.A.; Morales, J. [Asociacion Colombiana de Proteccion Radiologica (Colombia)]. e-mail: ccbeltra@gmail.com

    2006-07-01

    Colombia counts with around 56 centers of Nuclear Medicine, 70 Nuclear Doctors and more of 100 Technologists in this area. The radioisotopes more used are the {sup 131} I and the {sup 99m} Tc. The radiological surveillance singular in the country is carried out for external dosimetry, being the surveillance by incorporation of radioactive materials very sporadic in our media. Given the necessity to implement monitoring programs in the incorporation of radionuclides of the occupationally exposed personnel, in the routine practice them routine of Nuclear Medicine, it was implemented a pilot program of Special Monitoring with two centers of importance in the city of Medellin. This program it was carried out with the purpose of educating, to stimulate and to establish a program of reference monitoring with base in the National Program of Monitoring in the radionuclides Incorporation that serves like base for its application at level of all the services of Nuclear Medicine in the country. This monitoring type was carried out with the purpose of obtaining information on the work routine in these centers, form of manipulation and dosage of the radionuclides, as well as the administration to the patient. The application of the program was carried out to define the frequency of Monitoring and analysis technique for the implementation of a program of routine monitoring, following the recommendations of the International Commission of Radiological Protection. For their application methods of activity evaluation were used in urine and in 7 workers thyroid, of those which only two deserve an analysis because they presented important activities. The measures were carried out during one month, every day by means in urine samples and to the most critic case is practiced two thyroid measures, one in the middle of the period and another when concluding the monitoring. To the other guy is practiced an activity count in thyroid when concluding the monitoring period. The obtained

  14. What You Should Know About Pediatric Nuclear Medicine and Radiation Safety

    Science.gov (United States)

    ... Radiation Safety www.imagegently.org What is nuclear medicine? Nuclear medicine uses radioactive isotopes to create pictures of the human body. ... help doctors find health problems and plan treatment. Nuclear medicine tests can find infections, birth defects, injuries and ...

  15. NMR clinical imaging and spectroscopy: Its impact on nuclear medicine

    International Nuclear Information System (INIS)

    This is a collection of four papers describing aspects of past and future use of nuclear magnetic resonance as a clinical diagnostic tool. The four papers are entitled (1) What Does NMR Offer that Nuclear Medicine Does Not? by Jerry W. Froelich, (2) Oncological Imaging: Now, Future and Impact Jerry W. Froelich, (3) Magnetic Resonance Spectroscopy/Spectroscopic Imaging and Nuclear Medicine: Past, Present and Future by H. Cecil Charles, and (4) MR Cardiology: Now, Future and Impact by Robert J. Herfkens

  16. Semiconductor arrays for nuclear medicine imaging

    International Nuclear Information System (INIS)

    Full text: Gamma-ray imaging of an injected radiotracer is used in nuclear medicine to determine organ function or locate the site of pathology such as cancer. Current gamma cameras use scintillation detectors with analog position estimation and are characterized by poor spatial resolution (0.4 cm) and poor energy resolution (11% FWHM at 140 keV). Energy resolution is important for suppressing the effects of Compton scattering in tissue. Single photon emission computed tomography (SPECT) is used to generate a three-dimensional representation of the source distribution. Another technique, positron emission tomography (PET), images the annihilation radiation from a positron emitter but is more costly than SPECT and is less widely available. Arrays of semiconductor detectors have long been considered an attractive alternative to scintillators for use in gamma cameras. Semiconductor detectors have excellent energy resolution and can be fabricated into large arrays of small pixel size and thus good spatial resolution using photolithography techniques. The best semiconductor detectors are Si and Ge, but these are less attractive for nuclear medicine purposes because of low gamma-ray stopping power or the need for expensive cryogenics. Most interest has centered on room-temperature semiconductor detectors such as CdTe and HgI2. However, until now, the main use of semiconductors in nuclear medicine has been as detectors in probes used to locate radiotracer-labelled tumors or other pathology at surgery or endoscopy. There are a number of reasons why a practical semiconductor camera has not yet been developed: semiconductor detectors are very expensive. Large detector areas (0.1 - 0.2 square meter) will be required for a camera. Electronics for reading out as many as a million separate detector pixels must be provided. Room-temperature semiconductor detectors suffer from charge carrier trapping that limits their useful efficiency. Current multibore collimators must trade off

  17. Role of nuclear medicine in imaging companion animals

    International Nuclear Information System (INIS)

    The role of equine nuclear medicine in Australia has been previously described in this journal and more recently, Lyall et al. provided a general overview of demographics of veterinary nuclear medicine departments in Australia. Lyall et al. discuss the main clinical applications of nuclear medicine scintigraphy in companion animals; dogs and cats. The aim of this article is to discuss in brief the applications of commonly performed nuclear medicine procedures in humans with respect to veterinary applications. More detailed discussion will also be offered for investigation of pathologies unique to veterinary nuclear medicine or which are more common in animals than humans. Companion animals are living longer today due to advances in both veterinary and human medicine. The problem is, like humans, longevity brings higher incidence of old age morbidity. As a pet owner, one might be initially motivated to extend life expectancy which is followed by the realisation that one also demands quality of life for pets. Early detection through advanced diagnostic tools, like nuclear medicine scintigraphy, allows greater efficacy in veterinary disease. There are limited veterinary nuclear medicine facilities in Australia due to cost and demand. Not surprisingly then, the growth of veterinary nuclear medicine in Australia, and overseas, has been integrally coupled to evaluation of race horses. While these facilities are generally specifically designed for race horses, racing greyhounds, lame family horses and companion animals are being investigated more frequently. In the USA, the American College of Veterinary Radiology (ACVC) is very active clinically and in research. The ACVC journal, Journal of Veterinary Radiology and Ultrasound, is published quarterly and includes a Nuclear Medicine section. Within the ACVR is the Society of Veterinary Nuclear Medicine. Proliferation of veterinary nuclear medicine centres in the USA has been associated with insurance and lifestyle changes

  18. Contemporary nuclear medicine imaging of neuroendocrine tumours

    International Nuclear Information System (INIS)

    Neuroendocrine tumours (NETs) are rare, heterogeneous, and often hormonally active neoplasms. Nuclear medicine (NM) imaging using single photon- and positron-emitting radiopharmaceuticals allows sensitive and highly specific molecular imaging of NETs, complementary to anatomy-based techniques, such as computed tomography (CT) and magnetic resonance imaging (MRI). Somatostatin-receptor scintigraphy is a whole-body imaging technique widely used for diagnosis, staging and restaging of NETs. The increasing availability of hybrid single-photon emission CT (SPECT)/CT cameras now offers superior accuracy for localization and functional characterization of NETs compared to traditional planar and SPECT imaging. The potential role of positron-emission tomography (PET) tracers in the functional imaging of NETs is also being increasingly recognized. In addition to 2-[18F]-fluoro-2-deoxy-D-glucose (FDG), newer positron-emitting radiopharmaceuticals such as 18F-dihydroxyphenylalanine (DOPA) and 68Ga-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) peptides, show promise for the future. This article will summarize the role of current and emerging radiopharmaceuticals in NM imaging of this rare but important group of tumours.

  19. Nuclear medicine and the nursing mother

    International Nuclear Information System (INIS)

    Many radiopharmaceuticals may be detected in breast milk, but differ from other drugs in that for diagnostic purposes they are used in tracer quantities and do not produce demonstrable pharmacological changes in mother or infant. Patients may also be given non-radioactive drugs to induce changes in the distribution of the radiopharmaceuticals and some of these, too, appear in milk (e.g. frusemide, potassium perchlorate, iodides, and cholecystokinin). Iodides are selectively concentrated in breast milk, and some consider them contra-indicated during lactation. A period of interruption of breast feeding, expression of milk, and reduction of close contact with the infant is usually recommended for mothers who have a nuclear medicine investigation. The inconvenience and disadvantages of interrupting breast feeding have to be balanced against the potential risk to the infant: the prolonged interruption of feeding advocated for some agents is often impracticable. Interruption for 24 hours for sup(99m)Tc compounds is excessive for doses used in Britain. Twelve hours leaves a wide range of safety for pertechnetate. No interruption is needed for sup(99m)Tc-macroaggregated albumin and sup(99m)Tc-diethylenetriamine-penta-acetic acid in order to remain below one tenth of the annual limit of intake. (U.K.)

  20. [Nuclear medicine for evaluation of liver functions].

    Science.gov (United States)

    Yamamoto, K

    1994-05-01

    The clinical usefulness of colloid liver scintigraphy to detect space occupying lesions in the liver has been reduced by X-ray CT and ultrasonography. However, scintigraphic examinations have potentials for characteristic diagnosis of liver tumors, such as 99mTc RBC SPECT for hepatic hemangioma, 99mTc PMT for positive imaging of hepatocellular carcinoma and its extrahepatic metastasis, and radioimmunoscintigraphy for metastatic tumors. Moreover, prediction of the prognosis and monitoring therapeutic effect to liver cancer can be made by the use of nuclear medicine techniques. Recently, 99mTc galactosyl serum albumin (GSA), a newly developed radiotracer to evaluate hepatocyte function, has become commercially available. Quantitative parameters of liver functions can be obtained by analysis of time-activity curve in blood and liver after 99mTc-GSA administration. In several cases, 99mTc-GSA study showed intrahepatic unevenness of function, which could not be depicted by other imaging examinations. Positron emission tomography (PET) with 18F-fluoro-2-deoxy glucose (FDG) is useful to detect malignant tumors in the liver. Since PET can provide absolutely quantitative data in better resolution, it is expected that regional true metabolic functions in the liver may be able to be quantitatively evaluated with PET in near future. PMID:8028225

  1. Nuclear medicine at Brookhaven National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Atkins, H.L.

    1976-01-01

    The Nuclear Medicine Program at the Brookhaven National Laboratory seeks to develop new materials and methods for the investigation of human physiology and disease processes. Some aspects of this research are related to basic research of how radiopharmaceuticals work. Other aspects are directed toward direct applications as diagnostic agents. It is likely that cyclotron-produced positron emitting nuclides will assume greater importance in the next few years. This can be attributed to the ability to label biologically important molecules with high specific activity without affecting biological activity, using /sup 11/C, /sup 13/N, and /sup 15/O. Large quantities of these short-lived nuclides can be administered without excessive radiation dose and newer instrumentation will permit reconstructive axial tomography, providing truly quantitative display of distribution of radioactivity. The /sup 122/Xe-/sup 122/I generator has the potential for looking at rapid dynamic processes. Another generator, the /sup 68/Ge-/sup 68/Ga generator produces a positron emitter for the use of those far removed from cyclotrons. The possibilities for /sup 68/Ga radiopharmaceuticals are as numerous as those for /sup 99m/Tc diagnostic agents.

  2. The role of nuclear medicine in oncology

    International Nuclear Information System (INIS)

    Nuclear Medicine offers screening methods for oncology such as bone and bone marrow scintigraphy. During the last two decades, special procedures have gained widespread application. This paper is centered around the 'tumor-specific' radiopharmaceuticals. In patients with thyroid cancer, I-131 still plays a significant role. Ga-67 still has its indications in lymphoma, while in other diseases Tl-201 cloride is now the agent of choice. Especially in thyroid cancer, Tl-201 has proved to be a reliable tumor imaging radiopharmaceutical. More recently, Tc-99m MIBI was introduced for tumor imaging. Tc-99m HMPAO may also be used for tumor scintigraphy, especially in brain lesions. In addition, I-123 IMP has successfully been used for imaging malignant melanoma. Another promising field of tumor diagnosis is receptor imaging. In neuroblastoma and malignant pheochromocytoma, I-131/123 mIBG is the radiopharmaceutical of choice and may be considered as a receptor imaging agent also. First clinical results with In-111 octreotide show potentials as somatostatine-receptor radiopharmaceutical in insulinoma, islet cell carcinoma, medullary and lung cancer, while I-123 estradiol needs some improvement until it may be recommended as diagnostic tool in breast cancer. Since 1978, radiolabeled poly- or monoclonal tumor antibodies and their fragments have gained widespread application. Especially the Tc-99m 225.28S melanoma antibody, I-131 or Tc-99m CEA and In-111/I-131 labeled OC-125 antibodies have proven to be of clinical significance in melanoma, colorectal and ovarian cancer. (author)

  3. Recent Advances in Nuclear Medicine Imaging Instrumentation

    International Nuclear Information System (INIS)

    This review introduces advances in clinical and pre-clinical single photon emission computed tomography (SPECT) and positron emission tomography (PET) providing noninvasive functional images of biological processes. Development of new collimation techniques such as multi-pinhole and slit-slat collimators permits the improvement of system spatial resolution and sensitivity of SPECT. Application specific SPECT systems using smaller and compact solid-state detector have been customized for myocardial perfusion imaging with higher performance. Combined SPECT/CT providing improved diagnostic and functional capabilities has been introduced. Advances in PET and CT instrumentation have been incorporated in the PET/CT design that provide the metabolic information from PET superimposed on the anatomic information from CT. Improvements in the sensitivity of PET have achieved by the fully 3D acquisition with no septa and the extension of axial field-of-view. With the development of faster scintillation crystals and electronics, time-of-flight (TOF) PET is now commercially available allowing the increase in the signal-to-noise ratio by incorporation of TOF information into the PET reconstruction process. Hybrid PET/SPECT/CT systems has become commercially available for molecular imaging in small animal models. The pre-clinical systems have improved spatial resolution using depth-of-interaction measurement and new collimators. The recent works on solid state detector and dual modality nuclear medicine instrumentations incorporating MRI and optical images will also be discussed

  4. Specific filters applied in nuclear medicine services

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, Vitor S.; Crispim, Verginia R., E-mail: verginia@con.ufrj.b [Coordenacao dos Programas de Pos-Graduacao de Engenharia (PEN/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Nuclear; Brandao, Luis E.B. [Instituto de Engenharia Nuclear (IEN/CNEN-RJ) Rio de Janeiro, RJ (Brazil)

    2011-07-01

    In Nuclear Medicine, radioiodine, in various chemical forms, is a key tracer used in diagnostic practices and/or therapy. Due to its high volatility, medical professionals may incorporate radioactive iodine during the preparation of the dose to be administered to the patient. In radioactive iodine therapy doses ranging from 3.7 to 7.4 GBq per patient are employed. Thus, aiming at reducing the risk of occupational contamination, we developed a low cost filter to be installed at the exit of the exhaust system where doses of radioactive iodine are fractionated, using domestic technology. The effectiveness of radioactive iodine retention by silver impregnated silica [10%] crystals and natural activated carbon was verified using radiotracer techniques. The results showed that natural activated carbon is effective for I{sub 2} capture for a large or small amount of substrate but its use is restricted due to its low flash point (150 deg C). Besides, when poisoned by organic solvents, this flash point may become lower, causing explosions if absorbing large amounts of nitrates. To hold the CH{sub 3}I gas, it was necessary to increase the volume of natural activated carbon since it was not absorbed by SiO{sub 2} + Ag crystals. We concluded that, for an exhaust flow range of (306 {+-} 4) m{sup 3}/h, a double stage filter using SiO{sub 2} + Ag in the first stage and natural activated carbon in the second is sufficient to meet radiological safety requirements. (author)

  5. Highlights lecture EANM 2015: the search for nuclear medicine's superheroes.

    Science.gov (United States)

    Buck, Andreas; Decristoforo, Clemens

    2016-09-01

    The EANM 2015 Annual Congress, held from October 10th to 14th in Hamburg, Germany, was outstanding in many respects. With 5550 participants, this was by far the largest European congress concerning nuclear medicine. More than 1750 scientific presentations were submitted, with more than 250 abstracts from young scientists, indicating that the future success of our discipline is fuelled by a high number of young individuals becoming involved in a multitude of scientific activities. Significant improvements have been made in molecular imaging of cancer, particularly in prostate cancer. PSMA-directed PET/CT appears to become a new gold standard for staging and restaging purposes. Novel tumour specific compounds have shown their potential for target identification also in other solid neoplasms and further our understanding of tumour biology and heterogeneity. In addition, a variety of nuclear imaging techniques guiding surgical interventions have been introduced. A particular focus of the congress was put on targeted, radionuclide based therapies. Novel theranostic concepts addressing also tumour entities with high incidence rates such as prostate cancer, melanoma, and lymphoma, have shown effective anti-tumour activity. Strategies have been presented to improve further already established therapeutic regimens such as somatostatin receptor based radio receptor therapy for treating advanced neuroendocrine tumours. Significant contributions were presented also in the neurosciences track. An increasing number of target structures of high interest in neurology and psychiatry are now available for PET and SPECT imaging, facilitating specific imaging of different subtypes of dementia and movement disorders as well as neuroinflammation. Major contributions in the cardiovascular track focused on further optimization of cardiac perfusion imaging by reducing radiation exposure, reducing scanning time, and improving motion correction. Besides coronary artery disease, many

  6. Nuclear medicine imaging in the evaluation of endocrine hypertension

    Directory of Open Access Journals (Sweden)

    Punit Sharma

    2012-01-01

    Full Text Available Endocrine hypertension forms a small (< 5% but curable subset of patients with hypertension. Common endocrine causes of hypertension include pheochromocytoma, Cushing′s syndrome, primary hyperaldosteronism, and thyroid disorders. Nuclear medicine imaging plays an important role in evaluation of patients with endocrine hypertension. It has established role in patients of pheochromocytoma/paraganglioma, Cushing′s syndrome, aldosteronism, and thyroid disorders. We present a brief overview of role of nuclear medicine imaging in endocrine hypertension. Development of newer radiotracers might further broaden the role of nuclear medicine in these patients.

  7. Where are we with nuclear medicine in pediatrics?

    International Nuclear Information System (INIS)

    The practice of nuclear medicine in children is different from that in adults. Technical considerations including immobilization, dosing of radiopharmaceuticals, and instrumentation are of major importance. Image mangnification and the capability to perform single-photon emission tomography are essential to performing state of the art pediatric nuclear medicine. New advances in instrumentation with multiple detector imaging, the possibility of clinical positron emission tomography imaging in children, and new radiopharmaceuticals will further enhance pediatric scintigraphic imaging. This review highlights advances in pediatric nuclear medicine and discusses selected clinical problems. (orig.)

  8. History and Perspectives of Nuclear Medicine in Bangladesh

    OpenAIRE

    Raihan Hussain

    2016-01-01

    Bangladesh is one of the smaller states in Asia. But it has a long and rich history of nuclear medicine for over sixty years. The progress in science and technology is always challenging in a developing country. In 1958, work for the first Nuclear Medicine facility was commenced in Dhaka in a tin-shed known as ‘Radioisotope Centre’ and was officially inaugurated in 1962. Since the late 50s of the last century nuclear medicine in Bangladesh has significantly progressed through the years in its...

  9. Recommendations on Strengthening the Development of Nuclear Medicine in China

    Institute of Scientific and Technical Information of China (English)

    Shih-chen Wang

    2009-01-01

    @@ This paper outlines briefly the role of nuclear medicine in life sciences and health care. Molecular imaging by using isotopic tracers can noninvasively visualize the chemistry or hidden process in the cells and tissues inside the body, obtaining "functional" images to provide early information of any disease and revealing the secrets of life. The vitality of nuclear medicine is its ability to translate bench into new clinical application that can benefits the patients. Although nuclear medicine community in China has made significant achievement with a great effort since 1950s, there are many obstacles to future development. Recommended measures are proposed here in an attempt to solve our existing problems.

  10. Annual congress of the European Association of Nuclear Medicine. EANM'14. Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-10-15

    The proceedings of the annual congress of the European Association of Nuclear Medicine EANM'14 contain abstracts on the following issues: nuclear cardiology practices, PET in lymphoma, advances in nuclear cardiology, dosimetry for intra-arterial treatment in the liver, pediatric nuclear medicine, therapeutic nuclear medicine, SPECT/CT, prostate cancer, extended competencies for nuclear medicine technologists, neurosciences - neurodegeneration and neuroinflammation, radionuclide therapy and dosimetry - preclinical studies, physics and instrumentation, clinical molecular imaging, conventional and specialized nuclear medicine.

  11. Current status of respiratory nuclear medicine

    International Nuclear Information System (INIS)

    . Newly developed radiotracers include L-3-123I-α-methyl-tyrosine for evaluating amino acid metabolism of lung cancer on SPECT scanner, 99mTc-labeled surfactant B for evaluating pulmonary surfactant system, Cu-DTS for imaging hypoxic tumor cells, and 18F-fluorocaptopril for evaluating the lung distribution of pulmonary angiotension converting enzyme. These will contribute to the further advancement and development of expiratory nuclear medicine. (author)

  12. The development of nuclear medicine in Slovenia and Ljubljana; half a century of nuclear medicine in Slovenia

    International Nuclear Information System (INIS)

    Nuclear medicine began to be developed in the USA after 1938 when radionuclides were introduced into medicine and in Europe after radionuclides began to be produced at the Harwell reactor (England, 1947). Slovenia began its first investigations in the 1950s. This article describes the development of nuclear medicine in Slovenia and Ljubljana. The first nuclear medicine interventions were performed in Slovenia at the Internal Clinic in Ljubljana in the period 1954–1959. In 1954, Dr Jože Satler started using radioactive iodine for thyroid investigations. In the same year, Dr Bojan Varl, who is considered the pioneer of nuclear medicine in Slovenia, began systematically introducing nuclear medicine. The first radioisotope laboratories were established in January 1960 at the Institute of Oncology and at the Internal Clinic. Under the direction of Dr. Varl, the laboratory at the Internal Clinic developed gradually and in 1973 became the Clinic for Nuclear Medicine with departments for in vivo and in vitro diagnostics and for the treatment of inpatients and outpatients at the thyroid department. The Clinic for Nuclear Medicine became a teaching unit of the Medical Faculty and developed its own post-graduate programme – the first student enrolled in 1972. In the 1960s, radioisotope laboratories opened in the general hospitals of Slovenj Gradec and Celje, and in the 1970s also in Maribor, Izola and Šempeter pri Novi Gorici. Nowadays, nuclear medicine units are modernly equipped and the staff is trained in morphological, functional and laboratory diagnostics in clinical medicine. They also work on the treatment of cancer, increased thyroid function and other diseases

  13. Structure and Activities of Nuclear Medicine in Kuwait.

    Science.gov (United States)

    Elgazzar, Abdelhamid H; Owunwanne, Azuwuike; Alenezi, Saud

    2016-07-01

    The practice of nuclear medicine in Kuwait began in 1965 as a clinic for treating thyroid diseases. The practice developed gradually and until 1981 when the Faculty of Medicine established the Division of Nuclear Medicine in the Department of Radiology, which later became a separate department responsible for establishing and managing the practice in all hospitals of Kuwait. In 1987, a nuclear medicine residency program was begun and it is administered by Kuwait Institute for Medical Specializations originally as a 4-year but currently as a 5-year program. Currently there are 11 departments in the ministry of health hospitals staffed by 49 qualified attending physicians, mostly the diplomats of the Kuwait Institute for Medical Specializations nuclear medicine residency program, 4 academic physicians, 2 radiopharmacists, 2 physicists, and 130 technologists. These departments are equipped with 33 dual-head gamma cameras, 10 SPET/CT, 5 PET/CT, 2 cyclotrons, 1 breast-specific gamma imaging, 1 positron-emitting mammography, 10 thyroid uptake units, 8 technegas machines, 7 PET infusion systems, and 8 treadmills. Activities of nuclear medicine in Kuwait include education and training, clinical service, and research. Education includes nuclear medicine technology program in the Faculty of Allied Health Sciences, the 5-year residency program, medical school teaching distributed among different modules of the integrated curriculum with 14 didactic lecture, and other teaching sessions in nuclear medicine MSc program, which run concurrently with the first part of the residency program. The team of Nuclear Medicine in Kuwait has been active in research and has published more than 300 paper, 11 review articles, 12 book chapters, and 17 books in addition to 36 grants and 2 patents. A PhD program approved by Kuwait University Council would begin in 2016. PMID:27237444

  14. Distribution of nuclear medicine service in Brazil; Distribuicao do servico de medicina nuclear no Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Ana Carolina Costa da; Duarte, Alessandro; Santos, Bianca Maciel dos [Faculdade Metodo de Sao Paulo (FAMESP), Sao Paulo, SP (Brazil)

    2011-10-26

    The Brazil does not posses a good distribution of nuclear medicine service por all his territory. This paper shows the difference among country regions as far the number of clinics of nuclear medicine as is concerning, and also doctors licensed in the area and radioprotection supervisors, both licensed by the Brazilian Nuclear Energy Commission (CNEN)

  15. Veterinary nuclear medicine again - commentary and remarks on: Krzeminski M., et al. Veterinary nuclear medicine - a review. NMR 2004;7: 177 - 182

    International Nuclear Information System (INIS)

    Veterinary nuclear medicine is somehow similar to its roots, Human Nuclear Medicine, but certainly there are a few basic differences. Patients sent by veterinary clinicians could be members of exotic species (birds, reptiles, rodents) and even the most often treated dog, cat, and horse patients vary in a pretty wide scale in weight, size and anatomical, physiological features. As there are no veterinary radiopharmaceuticals in the market, vets use human registered products, therefore applied radioactive doses are often calculated on an empirical manner. As opposed to humans, animal subjects almost always need to be sedated or anaesthetised for scintigraphical protocols. We vets, frequently perform bone and thyroid scintigraphy in the everyday clinical routine and oncological applications are more and more common in the veterinary field as well. But in contrast with human practice, our animal patients suffer very rarely from cardiovascular diseases, so heart and brain perfusion studies are less frequently performed at veterinary clinics. (author)Veterinary nuclear medicine is somehow similar to its roots,

  16. Proceedings of the 6.Brazilian Meeting on Nuclear Medicine

    International Nuclear Information System (INIS)

    Several subjects on nuclear medicine are presented. The use of scintiscanning in heart diseases, neoplasms, etc. is emphasized. Radioisotope preparation techniques and labelling of compounds used in radioassays are described. (M.A.C.)

  17. Proceedings of the 7. Brazilian Meeting on Nuclear Medicine

    International Nuclear Information System (INIS)

    Subjects about nuclear medicine are discussed. Researchs concerning the use of radioisotopes as tracers in several diseases are presented. The use of radioisotopes in diagnosis are emphasized. (M.A.C.)

  18. Requirements of radiation protection and safety for nuclear medicine services

    International Nuclear Information System (INIS)

    The requirements of radiation protection and safety for nuclear medicine services are established. The norms is applied to activities related to the radiopharmaceuticals for therapeutics and 'in vivo' diagnostics purposes. (M.C.K.)

  19. Metabolic radiopharmaceutical therapy in nuclear medicine; Terapia metabolica mediante radiofarmacos en medicina nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Reguera, L.; Lozano, M. L.; Alonso, J. C.

    2016-08-01

    In 1986 the National Board of Medical Specialties defined the specialty of nuclear medicine as a medical specialty that uses radioisotopes for prevention, diagnosis, therapy and medical research. Nowadays, treatment with radiopharmaceuticals has reached a major importance within of nuclear medicine. The ability to treat tumors with radiopharmaceutical, Radiation selective therapy has become a first line alternative. In this paper, the current situation of the different therapies that are sued in nuclear medicine, is reviewed. (Author)

  20. Overview of medicinal plants used for cardiovascular system disorders and diseases in ethnobotany of different areas in Iran

    Directory of Open Access Journals (Sweden)

    Baharvand-Ahmadi Babak

    2016-01-01

    Full Text Available Background and Aims: Today, cardiovascular diseases are the prominent cause of death in industrialized countries which include a variety of diseases such as hypertension, hyperlipidemia, thromboembolism, coronary heart disease, heart failure, etc. Recent research findings haveshown that not only the extent of cultivation and production of medicinal plants have not beenreduced, but also day-to-day production and consumption have increased. In traditional botanicalknowledge, herbal medicines are used for the treatment of cardiovascular disorders. In this study,we sought to gather and report medicinal plants used to treat these diseases in different regionsof Iran.Methods: The articles published about ethnobotanical study of cardiovascular diseases in variousregions of Iran, such as Arasbaran, Sistan, Kashan, Kerman, Isfahan Mobarakeh, Lorestan andIlam were prepared and summarized.Results: The results of ethnobotanical studies of various regions of Iran, such as Arasbaran, Sistan,Kashan, Kerman, Isfahan Mobarakeh, Lorestan and Ilam were gathered. The results showed thatsumac plants, barberry, yarrow, wild cucumber, horsetail, Eastern grape, hawthorn, wild rose,spinach, jujube, buckwheat, chamomile, chicory, thistle, Mary peas, nightshade, verbena, sorrel ,cherry, citrullus colocynthis, Peganum harmala, sesame and so many other plants are used for thetreatment of cardiovascular diseases and disorders.Conclusion: Herbal medicines are used effectively for some cardiovascular diseases. Rigoroustraining of patients to take precautions and drug interactions into account and to avoid thearbitrary use of medicinal plants is very important.

  1. Radiopharmaceuticals in nuclear medicine: evolution and present status

    International Nuclear Information System (INIS)

    A general overview of radiopharmaceuticals and their uses in nuclear medicine is presented. A brief history is outlined followed by the current status of the radiopharmaceuticals employed in the various branches of medicine such as neurology, cardiology, oncology, G.I. system and skeletal system. Important radiopharmaceutical preparations used in radionuclide therapy are described. (author). 58 refs., 1 tab., 2 figs

  2. Nuclear medicine imaging of diabetic foot infection

    International Nuclear Information System (INIS)

    Full text: Osteomyelitis of the foot is the most frequent complication in diabetic patients. Nuclear medicine plays an important role in diagnosis and for therapy follow-up, using different tracers. We reviewed 57 papers on diabetic foot imaging (published from 1982 to 2004, 50 original papers and 7 reviews), for a total of 2889 lesions. Data analysis has been carried out to establish which imaging technique could be used as a 'gold standard' for diagnosis of infection and to evaluate the extent of disease and to monitor the efficacy of therapy. Data analysis revealed that three-phase bone-scan is sensitive but not specific whereas specificity and diagnostic accuracy of 99mTc-WBC scintigraphy is higher than 111In- WBC scintigraphy. In the forefoot leukocyte scintigraphy may be useful for diagnosis of osteomyelitis and for monitoring the response to medical treatment. In the mid/hind foot the leukocytes uptake is not related only to the presence of infected region, but it is attributed to inflammation, fractures and reparative processes. Other radiopharmaceuticals such as 99mTc/111In-HIG, radiolabelled antibody and their fragments, showed high sensibility, but lower specificity than WBC (96.8/66.5, 95.8/70.2, 91.3/62 vs 85.8/84.5). Conclusion: It emerged that in the forefoot when clinical suspicious of osteomyelitis is low and medical treatment is contemplated, three-phase bon scan is the procedure of choice. A positive test is not diagnostic for osteomyelitis, and radiolabelled WBC scintigraphy is necessary. In the mid/hind foot, diagnosis of neuropathic joint with infection is problematic. Radiolabelled WBC imaging is probably the most accurate test for determining the presence of infection. Although a negative study strongly indicate the absence of osteomyelitis, it is important to note that a positive result requires a complementary study with marrow agent. (author)

  3. Computers in Nuclear Medicine. Chapter 12

    International Nuclear Information System (INIS)

    In 1965, Gordon Moore, a co-founder of Intel, said that new memory chips have twice the capacity of prior chips, and that new chips are released every 18 to 24 months. This statement has become known as Moore’s law. Moore’s law means that memory size increases exponentially. More generally, the exponential growth of computers has applied not only to memory size, but also to many computer capabilities, and since 1965, Moore’s law has remained remarkably accurate. Further, this remarkable growth in capabilities has occurred with a steady decrease in price. Anyone who has even a little appreciation of exponential growth realizes that exponential growth cannot continue indefinitely. However, the history of computers is littered with ‘experts’ who have prematurely declared the end of Moore’s law. The quotation at the beginning of this section indicates that future growth of computers has often been underestimated. The exponential growth of computer capabilities has a very important implication for the management of a nuclear medicine department. The growth in productivity of the staff of a department is slow, especially when compared to the growth in capabilities of a computer. This means that whatever decision was made in the past about the balance between staff and computers is now out of date. A good heuristic is: always apply more computer capacity and less people to a new task. Or stated more simply, hardware is ‘cheap’, at least with respect to what you learned in training or what you decided last time you considered the balance between hardware and ‘peopleware’

  4. The role and indications of nuclear medicine in dentistry

    OpenAIRE

    Majid Reza Mokhtari; Fateme Farazi

    2010-01-01

    The role and indications of nuclear medicine in dentistry(a review article). Nuclear medicine and radioactive tracers have considerable application in dental research,because they provide one of the few practical methods for studying the limited metabolic activities of bones and teeth. The ease with which minute amounts of these radioactive materials may be accurately measured and distinguished from the mass of inert element in the tooth is particularly valuable. They are useful in s...

  5. Nuclear medicine in the assessment of differentiated thyroid cancer

    Energy Technology Data Exchange (ETDEWEB)

    Rutherford, G.-C. [Nuclear Medicine Department, Nottingham City Hospital, Nottingham (United Kingdom)], E-mail: gaylerutherford@doctors.org.uk; Franc, B. [Department of Radiology, Nuclear Medicine Section, University of California, San Francisco, CA (United States); O' Connor, A. [Nuclear Medicine Department, Nottingham City Hospital, Nottingham (United Kingdom)

    2008-04-15

    Despite modern multi-modality treatment, 10-30% of patients treated for differentiated thyroid cancer (DTC) ultimately develop local recurrence or metastatic disease. These malignancies are frequently slow-growing and secondary surgical resection is often undertaken along with radioactive iodine treatment. Correlation of radiological imaging with nuclear medicine studies is essential for individualized treatment planning, and to optimize this management. Radiologists should be familiar with the interpretation of various nuclear medicine studies used to image differentiated thyroid neoplasms.

  6. Nuclear medicine in the assessment of differentiated thyroid cancer

    International Nuclear Information System (INIS)

    Despite modern multi-modality treatment, 10-30% of patients treated for differentiated thyroid cancer (DTC) ultimately develop local recurrence or metastatic disease. These malignancies are frequently slow-growing and secondary surgical resection is often undertaken along with radioactive iodine treatment. Correlation of radiological imaging with nuclear medicine studies is essential for individualized treatment planning, and to optimize this management. Radiologists should be familiar with the interpretation of various nuclear medicine studies used to image differentiated thyroid neoplasms

  7. Introduction to hardware for nuclear medicine data systems

    International Nuclear Information System (INIS)

    Hardware included in a computer-based data system for nuclear medicine imaging studies is discussed. The report is written for the newcomer to computer collection and analysis. Emphasis is placed on the effect of the various portions of the system on the final application in the nuclear medicine clinic. While an attempt is made to familiarize the user with some of the terms he will encounter, no attempt is made to make him a computer expert. 1 figure, 2 tables

  8. Detection and characterization of translational research in cancer and cardiovascular medicine

    Directory of Open Access Journals (Sweden)

    Cambrosio Alberto

    2011-05-01

    Full Text Available Abstract Background Scientists and experts in science policy have become increasingly interested in strengthening translational research. Efforts to understand the nature of translational research and monitor policy interventions face an obstacle: how can translational research be defined in order to facilitate analysis of it? We describe methods of scientometric analysis that can do this. Methods We downloaded bibliographic and citation data from all articles published in 2009 in the 75 leading journals in cancer and in cardiovascular medicine (roughly 15,000 articles for each field. We calculated citation relationships between journals and between articles and we extracted the most prevalent natural language concepts. Results Network analysis and mapping revealed polarization between basic and clinical research, but with translational links between these poles. The structure of the translational research in cancer and cardiac medicine is, however, quite different. In the cancer literature the translational interface is composed of different techniques (e.g., gene expression analysis that are used across the various subspecialties (e.g., specific tumor types within cancer research and medicine. In the cardiac literature, the clinical problems are more disparate (i.e., from congenital anomalies to coronary artery disease; although no distinctive translational interface links these fields, translational research does occur in certain subdomains, especially in research on atherosclerosis and hypertension. Conclusions These techniques can be used to monitor the continuing evolution of translational research in medicine and the impact of interventions designed to enhance it.

  9. Radiation safety audit of a high volume Nuclear Medicine Department

    International Nuclear Information System (INIS)

    Professional radiation exposure cannot be avoided in nuclear medicine practices. It can only be minimized up to some extent by implementing good work practices. The aim of our study was to audit the professional radiation exposure and exposure rate of radiation worker working in and around Department of nuclear medicine and molecular imaging, Tata Memorial Hospital. We calculated the total number of nuclear medicine and positron emission tomography/computed tomography (PET/CT) procedures performed in our department and the radiation exposure to the radiation professionals from year 2009 to 2012. We performed an average of 6478 PET/CT scans and 3856 nuclear medicine scans/year from January 2009 to December 2012. The average annual whole body radiation exposure to nuclear medicine physician, technologist and nursing staff are 1.74 mSv, 2.93 mSv and 4.03 mSv respectively. Efficient management and deployment of personnel is of utmost importance to optimize radiation exposure in a high volume nuclear medicine setup in order to work without anxiety of high radiation exposure

  10. History and Perspectives of Nuclear Medicine in Bangladesh

    Directory of Open Access Journals (Sweden)

    Raihan Hussain

    2016-01-01

    Full Text Available Bangladesh is one of the smaller states in Asia. But it has a long and rich history of nuclear medicine for over sixty years. The progress in science and technology is always challenging in a developing country. In 1958, work for the first Nuclear Medicine facility was commenced in Dhaka in a tin-shed known as ‘Radioisotope Centre’ and was officially inaugurated in 1962. Since the late 50s of the last century nuclear medicine in Bangladesh has significantly progressed through the years in its course of development, but still the facilities are inadequate. At present there are 20 nuclear medicine establishments with 3 PET-CTs, 42 gamma camera/SPECTs with 95 physicians, 20 physicists, 10 radiochemists and 150 technologists. The Society of Nuclear Medicine, Bangladesh (SNMB was formed in 1993 and publishing its official journal since 1997. Bangladesh also has close relationships with many international organizations like IAEA, ARCCNM, AOFNMB, ASNM, WFNMB and WARMTH. The history and the present scenario of the status of nuclear medicine in Bangladesh are being described here.

  11. Ninth Argentine congress on biology and nuclear medicine; fourth Southernmost sessions of ALASBIMN (Latin-American Association of Biology and Nuclear Medicine); first Spanish-Argentine congress on nuclear medicine; first Argentine sessions on nuclear cardiology

    International Nuclear Information System (INIS)

    This work deals with all the papers presented at the 9. Argentine congress on biology and nuclear medicine; IV Southernmost sessions of ALASBIMN; I Spanish-Argentine congress on nuclear medicine and I Sessions Argentine sessions on nuclear cardiology held in Buenos Aires, Argentina, from October 14 - 18, 1991

  12. Importance of the quality control tests in nuclear medicine

    International Nuclear Information System (INIS)

    Full text: The acceptance of nuclear energy and its application by some part of the population are associated with the benefits brought by those activities and the guarantee that the incorporation of this technology will be strictly done according to the currently security norms. This project aims at presenting the Nuclear Medicine tests of control of quality models to assist the National Commission of Nuclear Energy Program of Regulatory Inspection (CNEN). The main aspects related with the radiological protection are discussed along the project and it is presented models that assist the Nuclear Medicine Service, in the matter of Radioprotection paying attention to the requirements of the Regulatory Inspection of CNEN. The fulfilment of such models shows, clearly, that they are fundamental for the radioprotection safety in the Nuclear Medicine Services. (author)

  13. Assessment of radiation dose in nuclear cardiovascular imaging using realistic computational models

    International Nuclear Information System (INIS)

    Purpose: Nuclear cardiology plays an important role in clinical assessment and has enormous impact on the management of a variety of cardiovascular diseases. Pediatric patients at different age groups are exposed to a spectrum of radiation dose levels and associated cancer risks different from those of adults in diagnostic nuclear medicine procedures. Therefore, comprehensive radiation dosimetry evaluations for commonly used myocardial perfusion imaging (MPI) and viability radiotracers in target population (children and adults) at different age groups are highly desired. Methods: Using Monte Carlo calculations and biological effects of ionizing radiation VII model, we calculate the S-values for a number of radionuclides (Tl-201, Tc-99m, I-123, C-11, N-13, O-15, F-18, and Rb-82) and estimate the absorbed dose and effective dose for 12 MPI radiotracers in computational models including the newborn, 1-, 5-, 10-, 15-yr-old, and adult male and female computational phantoms. Results: For most organs, 201Tl produces the highest absorbed dose whereas 82Rb and 15O-water produce the lowest absorbed dose. For the newborn baby and adult patient, the effective dose of 82Rb is 48% and 77% lower than that of 99mTc-tetrofosmin (rest), respectively. Conclusions: 82Rb results in lower effective dose in adults compared to 99mTc-labeled tracers. However, this advantage is less apparent in children. The produced dosimetric databases for various radiotracers used in cardiovascular imaging, using new generation of computational models, can be used for risk-benefit assessment of a spectrum of patient population in clinical nuclear cardiology practice

  14. Assessment of radiation dose in nuclear cardiovascular imaging using realistic computational models

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Tianwu [Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva 4 CH-1211 (Switzerland); Lee, Choonsik [Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Bethesda, Maryland 20852 (United States); Bolch, Wesley E. [Departments of Nuclear and Radiological and Biomedical Engineering, University of Florida, Gainesville, Florida 32611 (United States); Zaidi, Habib, E-mail: habib.zaidi@hcuge.ch [Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva 4 CH-1211 (Switzerland); Geneva Neuroscience Center, Geneva University, Geneva CH-1205 (Switzerland); Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen 9700 RB (Netherlands)

    2015-06-15

    Purpose: Nuclear cardiology plays an important role in clinical assessment and has enormous impact on the management of a variety of cardiovascular diseases. Pediatric patients at different age groups are exposed to a spectrum of radiation dose levels and associated cancer risks different from those of adults in diagnostic nuclear medicine procedures. Therefore, comprehensive radiation dosimetry evaluations for commonly used myocardial perfusion imaging (MPI) and viability radiotracers in target population (children and adults) at different age groups are highly desired. Methods: Using Monte Carlo calculations and biological effects of ionizing radiation VII model, we calculate the S-values for a number of radionuclides (Tl-201, Tc-99m, I-123, C-11, N-13, O-15, F-18, and Rb-82) and estimate the absorbed dose and effective dose for 12 MPI radiotracers in computational models including the newborn, 1-, 5-, 10-, 15-yr-old, and adult male and female computational phantoms. Results: For most organs, {sup 201}Tl produces the highest absorbed dose whereas {sup 82}Rb and {sup 15}O-water produce the lowest absorbed dose. For the newborn baby and adult patient, the effective dose of {sup 82}Rb is 48% and 77% lower than that of {sup 99m}Tc-tetrofosmin (rest), respectively. Conclusions: {sup 82}Rb results in lower effective dose in adults compared to {sup 99m}Tc-labeled tracers. However, this advantage is less apparent in children. The produced dosimetric databases for various radiotracers used in cardiovascular imaging, using new generation of computational models, can be used for risk-benefit assessment of a spectrum of patient population in clinical nuclear cardiology practice.

  15. Training of nuclear medicine technical staff by the Brazilian Society of Nuclear Medicine and Biology

    International Nuclear Information System (INIS)

    Full text: Nuclear medicine was introduced in Brazil in 1949, at the University of Sao Paulo. Despite being a pioneer in South America and the existence of about 280 clinics of this medical specialty in the whole country serving around 185 million inhabitants, there is not any dedicated course forming its technical staff. Another shortcoming lies in the fact that there are not any basic requirements established for these professionals by an official medical or nuclear entity. As result, one can find persons ranging from university graduates (biomedics, radiology technologists, biologists, pharmacists, chemists, physicists, etc.) to secondary school graduates or radiology technicians working in nuclear medicine centres, preparing patients, labelling and injecting radiopharmaceuticals, obtaining images and processing studies. Due to the high heterogeneity of the technical staff and lack of a formal preparation, the Brazilian Society of Nuclear Medicine and Biology (SBBMN) organized during 2004 and 2005 short courses conducted in different regions of Brazil in order to supply organized basic knowledge and practice on: 1. Quality control of 99Mo-99mTc eluates and labelling and checking of dose calibrators 2. Fundamentals of radiation protection, area monitoring and decontamination 3. Quality control of scintillation cameras. Six courses were given during these two years in four cities in the South Eastern region and two in the North Eastern region. The first two topics were delivered during one weekend and the participants were presented with a lecture in the morning and, in the afternoon, a hands-on practice on the same subject. As QC of eluates and labelling and checking of dose calibrators were less practised in most clinics, this was the first time that the majority of the participants performed these activities. In one course, offered during a national congress, all three topics were included and the practical part was replaced by many examples from routine

  16. The contribution of medical physics to nuclear medicine: a physician's perspective

    OpenAIRE

    Peter J. Ell

    2014-01-01

    This paper is the second in a series of invited perspectives by four pioneers of nuclear medicine imaging and physics. A medical physicist and a nuclear medicine clinical specialist each take a backward look and a forward look at the contributions of physics to nuclear medicine. Here is a backward look from a nuclear medicine physician's perspective.

  17. Nuclear oncology, a fast growing field of nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Olivier, Pierre E-mail: p.olivier@chu-nancy.fr

    2004-07-11

    Nuclear Medicine in oncology has been for a long time synonymous with bone scintigraphy, the first ever whole body imaging modality, and with treatment of thyroid cancer with iodine-131. More recently, somatostatin receptor scintigraphy (SRS) using peptides such as {sup 111}In-labelled octreotide became a reference imaging method in the detection and staging of neuroendocrine tumors while {sup 131}I- and {sup 123}I-MIBG remain the tracers of reference for pheochromocytomas and neuroblastomas. Lymphoscintigraphic imaging based on peritumoral injection of {sup 99m}Tc-labelled colloids supports, in combination with per operative detection, the procedure of sentinel node identification in breast cancers and melanomas. Positron Emission Tomography (PET) is currently experiencing a considerable growth in oncology based on the use of {sup 18}F-FDG (fluorodeoxyglucose), a very sensitive, although non-specific, tumor tracer. Development of instrumentation is crucial in this expansion of PET imaging with new crystals being more sensitive and hybrid imagers that permit to reduce the acquisition time and offer fused PET-CT images. Current developments in therapy can be classified into three categories. Radioimmunotherapy (RIT) based on monoclonal antibodies (or fragments) labelled with beta-emitters. This technique has recently made its entrance in clinical practice with a {sup 90}Y-labelled anti-CD20 antibody ({sup 90}Y-ibritumomab tiuxetan (Zevalin{sup [reg]})) approved in US for the treatment of some subtypes of non-Hodgkin's lymphoma. Radionuclide-bone pain palliation has experienced developments with {sup 153}Sm-EDTMP, 186Re-HEDP or {sup 89}Sr, efficient in patients with widespread disease. Last, the same peptides, as those used in SRS, are being developed for therapy, labelled with {sup 90}Y, {sup 111}In or {sup 177}Lu in patients who failed to respond to other treatments. Overall, nuclear oncology is currently a fast growing field thanks to the combined

  18. Nuclear medicine imaging of bone infections.

    Science.gov (United States)

    Love, C; Palestro, C J

    2016-07-01

    Osteomyelitis is a broad group of infectious diseases that involve the bone and/or bone marrow. It can arise haematogenously, via extension from a contiguous infection, or by direct inoculation during surgery or trauma. The diagnosis is not always obvious and imaging tests are frequently performed as part of the diagnostic work-up. Commonly performed radionuclide tests include technetium-99m ((99m)Tc)-diphosphonate bone scintigraphy (bone), and gallium-67 ((67)Ga) and in vitro labelled leukocyte (white blood cell; WBC) imaging. Although they are useful, each of these tests has limitations. Bone scintigraphy is sensitive but not specific, especially when underlying osseous abnormalities are present. (67)Ga accumulates in tumour, trauma, and in aseptic inflammation; furthermore, there is typically an interval of 1-3 days between radiopharmaceutical injection of and imaging. Currently, this agent is used primarily for spinal infections. Except for the spine, WBC imaging is the nuclear medicine test of choice for diagnosing complicating osteomyelitis. The in vitro leukocyte labelling process requires skilled personnel, is laborious, and is not always available. Complementary marrow imaging is usually required to maximise accuracy. Not surprisingly, alternative radiopharmaceuticals are continuously being investigated. Radiolabelled anti-granulocyte antibodies and antibody fragments, investigated as in vivo leukocyte labelling agents, have their own limitations and are not widely available. (111)In-biotin is useful for diagnosing spinal infections. Radiolabelled synthetic fragments of ubiquicidin, a naturally occurring human antimicrobial peptide that targets bacteria, have shown promise as infection specific radiopharmaceuticals. 2-[(18)F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography (PET) with or without computed tomography (CT) is very useful in musculoskeletal infection. Sensitivities of more than 95% and specificities ranging from 75-99% have been

  19. Applications of CdTe to nuclear medicine. Final report

    International Nuclear Information System (INIS)

    Uses of cadmium telluride (CdTe) nuclear detectors in medicine are briefly described. They include surgical probes and a system for measuring cerebral blood flow in the intensive care unit. Other uses include nuclear dentistry, x-ray exposure control, cardiology, diabetes, and the testing of new pharmaceuticals

  20. Radiation safety of staff and public in nuclear medicine procedures

    International Nuclear Information System (INIS)

    Use of radio-pharmaceuticals in nuclear medicine results in radiation exposure to the staff and public. This exposure is to be kept as low as reasonably achievable by observing necessary safety precautions in day to day work with radionuclides. This paper discusses the nuclear practices where potential exposure exists and mentions the radiation safety procedures that to be followed. (author)

  1. IAEA support to medical physics in nuclear medicine.

    Science.gov (United States)

    Meghzifene, Ahmed; Sgouros, George

    2013-05-01

    Through its programmatic efforts and its publications, the International Atomic Energy Agency (IAEA) has helped define the role and responsibilities of the nuclear medicine physicist in the practice of nuclear medicine. This paper describes the initiatives that the IAEA has undertaken to support medical physics in nuclear medicine. In 1984, the IAEA provided guidance on how to ensure that the equipment used for detecting, imaging, and quantifying radioactivity is functioning properly (Technical Document [TECDOC]-137, "Quality Control of Nuclear Medicine Instruments"). An updated version of IAEA-TECDOC-137 was issued in 1991 as IAEA-TECDOC-602, and this included new chapters on scanner-computer systems and single-photon emission computed tomography systems. Nuclear medicine physics was introduced as a part of a project on radiation imaging and radioactivity measurements in the 2002-2003 IAEA biennium program in Dosimetry and Medical Radiation Physics. Ten years later, IAEA activities in this field have expanded to cover quality assurance (QA) and quality control (QC) of nuclear medicine equipment, education and clinical training, professional recognition of the role of medical physicists in nuclear medicine physics, and finally, the coordination of research and development activities in internal dosimetry. As a result of these activities, the IAEA has received numerous requests to support the development and implementation of QA or QC programs for radioactivity measurements in nuclear medicine in many Member States. During the last 5 years, support was provided to 20 Member States through the IAEA's technical cooperation programme. The IAEA has also supported education and clinical training of medical physicists. This type of support has been essential for the development and expansion of the Medical Physics profession, especially in low- and middle-income countries. The need for basic as well as specialized clinical training in medical physics was identified as a

  2. Production of iodine-124 and its applications in nuclear medicine

    International Nuclear Information System (INIS)

    Until recently, iodine-124 was not considered to be an attractive isotope for medical applications owing to its complex radioactive decay scheme, which includes several high-energy gamma rays. However, its unique chemical properties, and convenient half-life of 4.2 days indicated it would be only a matter of time for its frequent application to become a reality. The development of new medical imaging techniques, especially improvements in the technology of positron emission tomography (PET), such as the development of new detectors and signal processing electronics, has opened up new prospects for its application. With the increasing use of PET in medical oncology, pharmacokinetics, and drug metabolism, 124I-labeled radiopharmaceuticals are now becoming one of the most useful tools for PET imaging, and owing to the convenient half-life of I-124, they can be used in PET scanners far away from the radionuclide production site. Thus far, the limited availability of this radionuclide has been an impediment to its wider application in clinical use. For example, sodium [124I]-iodide is potentially useful for diagnosis and dosimetry in thyroid disease and [124I]-M-iodobenzylguanidine ([124I]-MIBG) has enormous potential for use in cardiovascular imaging, diagnosis, and dosimetry of malignant diseases such as neuroblastoma, paraganglioma, pheochromocytoma, and carcinoids. However, despite that potential, both are still not widely used. This is a typical scenario of a rising new star among the new PET tracers. - Highlights: • Improve the discussion and disseminate the knowledge of recent advances in nuclear medicine. • Stimulate the offer of alternative ways using the recent developed positron emitters. • Contribute to democratize the use of radiopharmaceuticals in developing countries. • Promote social benefit, starting a new era in diagnostic imaging in developing countries

  3. Nuclear medicine in dentistry revisited: New avenues to explore

    Directory of Open Access Journals (Sweden)

    Vinita Boloor

    2013-01-01

    Full Text Available Nuclear medicine and radioactive tracers have considerable application in dental research, because they provide one of the few practical methods for studying the limited metabolic activities of bones and teeth. The ease with which minute amounts of these radioactive materials may be accurately measured and distinguished from the mass of inert element in the tooth is particularly valuable. They are useful in studying many problems of calcification and mineral exchange. There are also opportunities of their use in investigating fluorosis, caries protection, periodontal disease, micro leakage studies of dental materials, root resorption, nutritional, and endocrine effects, as well as numerous other dental problems. Other usages of nuclear medicine in dentistry are listed below: Age written in teeth by nuclear tests, scintigraphic evaluation of osteoblastic activity, and evaluation of osteoblastic activity around dental implants using bone scintigraphy. Nuclear medicine can be an indicator of "active" alveolar bone loss. Nuclear medicine techniques are used as an adjunct for the diagnosis of oral diseases (benign tumors and carcinomas and temporomandibular joint disease. This review article discusses these indications of nuclear medicine.

  4. Extract from IAEA's Resources Manual in Nuclear Medicine - Part 2. - Human Resources Development

    International Nuclear Information System (INIS)

    The Nuclear Medicine Section of the International Atomic Energy Agency is now engaged in finalizing a reference manual in nuclear medicine, entitled, 'Resources Manual in Nuclear Medicine'. Several renowned professionals from all over the world, from virtually all fields of nuclear medicine have contributed to this manual. The World Journal of Nuclear Medicine will publish a series of extracts from this manual as previews. This is the second extract from the Resources Manual, Part-2 of the chapter on Human Resources Development. (author)

  5. Extracts from IAEA's Resources Manual in Nuclear Medicine - Part 1 - Human Resource Development

    International Nuclear Information System (INIS)

    The Nuclear Medicine Section of the International Atomic Energy Agency is now engaged in finalizing a reference manual in nuclear medicine, entitled, 'Resources Manual in Nuclear Medicine'. Several renowned professionals from all over the world, from virtually all fields of nuclear medicine have contributed to this manual. The World Journal of Nuclear Medicine will publish a series of extracts from this manual as previews. This is the first extract from the Resources Manual, Part-1 of the chapter on Human Resources Development. (author)

  6. Investigation of Marfan's syndrome by nuclear medicine

    International Nuclear Information System (INIS)

    Combining an isotope angiogram with an ECG-triggered blood pool scintigram is very appropriate to follow the course of Marfan's syndrome, especially to diagnose and to quantify occurrence of aneurysms, valve insufficiency and other cardiovascular defects like ventricle hypertrophy and decompensatio cordis. In this paper, results are described in a family of 4 members that show different stages of this disease. (G.J.P.)

  7. Comparative analysis of dosimetry parameters for nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Toohey, R.E.; Stabin, M.G. [Oak Ridge Inst. for Science and Education, TN (United States)

    1999-01-01

    For years many have employed the concept of ``total-body dose`` or ``whole-body dose,`` i.e., the total energy deposited in the body divided by the mass of the body, when evaluating the risks of different nuclear medicine procedures. The effective dose equivalent (H{sub E}), first described in ICRP Publication 26, has been accepted by some as a better quantity to use in evaluating the total risk of a procedure, but its use has been criticized by others primarily because the tissue weighting factors were intended for use in the radiation worker, rather than the nuclear medicine patient population. Nevertheless, in ICRP Publication 52, the ICRP has suggested that the H{sub E} may be used in nuclear medicine. The ICRP also has published a compendium of dose estimates, including H{sub E} values, for various nuclear medicine procedures at various ages in ICRP Publication 53. The effective dose (E) of ICRP Publication 60 is perhaps more suitable for use in nuclear medicine, with tissue weighting factors based on the entire population. Other comparisons of H{sub E} and E have been published. The authors have used the program MIRDOSE 3.1 to compute total-body dose, H{sub E}, and E for 62 radiopharmaceutical procedures, based on the best current biokinetic data available.

  8. Nuclear Medicine in Pediatric and Adolescent Tumors.

    Science.gov (United States)

    Kiratli, Pınar Özgen; Tuncel, Murat; Bar-Sever, Zvi

    2016-07-01

    Nuclear medicine has an important role in the management of many cancers in pediatric age group with multiple imaging modalities and radiopharmaceuticals targeting various biological uptake mechanisms. 18-Flourodeoxyglucose is the radiotracer of choice especially in patients with sarcoma and lymphoma. (18)FDG-PET, for sarcoma and lymphomas, is proved to be superior to conventional imaging in staging and therapy response. Although studies are limited in pediatric population, (18)FDG-PET/CT has found its way through international guidelines. Limitations and strengths of PET imaging must be noticed before adapting PET imaging in clinical protocols. Established new response criteria using multiple parameters derived from (18)FDG-PET would increase the accuracy and repeatability of response evaluation. Current data suggest that I-123 metaiodobenzylguanidine (MIBG) remains the tracer of choice in the evaluation of neuroblastoma (NB) because of its high sensitivity, specificity, diagnostic accuracy, and prognostic value. It is valuable in determining the response to therapy, surveillance for disease recurrence, and in selecting patients for I-131 therapy. SPECT/CT improves the diagnostic accuracy and the interpretation confidence of MIBG scans. (18)FDG-PET/CT is an important complementary to MIBG imaging despite its lack of specificity to NB. It is valuable in cases of negative or inconclusive MIBG scans and when MIBG findings underestimate the disease status as determined from clinical and radiological findings. F-18 DOPA is promising tracer that reflects catecholamine metabolism and is both sensitive and specific. F-18 DOPA scintigraphy provides the advantages of PET/CT imaging with early and short imaging times, high spatial resolution, inherent morphologic correlation with CT, and quantitation. Regulatory and production issues currently limit the tracer's availability. PET/CT with Ga-68 DOTA appears to be useful in NB imaging and may have a unique role in selecting

  9. Nuclear medicine procedures in the postgenomic era

    International Nuclear Information System (INIS)

    Assessment of gene function following the completion of human genome sequencing may be done using radionuclide imaging procedures. These procedures are needed for the evaluation of genetically manipulated animals or newly designed biomolecules which requires a thorough understanding of physiology, biochemistry and pharmacology. The experimental approaches will involve many new technologies including in vivo imaging with SPECT and PET. Nuclear medicine procedures may be applied for the determination of gene function and regulation using established and new tracers or using in vivo reporter genes such as genes encoding enzymes, receptors, antigens or transporters. Visualization of in vivo reporter gene expression can be done using radiolabelled substrates, antibodies or ligands. Combinations of specific promoters and in vivo reporter genes may deliver information about the regulation of the corresponding genes. Furthermore, protein-protein interactions and activation of signal transduction pathways may be visualized non-invasively. The role of radiolabelled antisense molecules for the analysis of mRNA content has to be investigated. However, possible applications are therapeutic intervention using triplex oligonucleotides with therapeutic isotopes which can be brought near to specific DNA sequences to induce DNA strand breaks at selected loci. Imaging of labelled siRNA's makes sense if these are used for therapeutic purposes in order to assess the delivery of these new drugs to their target tissue. In gene therapy based on the transfer and expression of suicide genes, usually gene coding for the non-mammalian enzymes, the Herpes Simplex virus thymidine kinase (HSVtk) or the yeast and bacterial cytosine deaminase (CD), have been used. After infection of the tumour with the recombinant virus, a non-toxic prodrug is applied systemically, which is subsequently converted to a toxic metabolite by the recombinant gene product. Employing a radiolabelled prodrug and

  10. LEI Yan( 雷燕 )—— An Expert in Studying Cardiovascular Diseases with Integrated Medicine

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Professor LEI Yan,Ph. D., female, was born in October 1960.After being graduated from Henan College of Traditional Chinese Medicine ( TCM ) in 1983, she worked as a resident physician in the TCM Hospital of Xinyang city, Henan province. She was enrolled in the master's program of internal medicine of integrative traditional Chinese and Western medicine in Fujian College of TCM in 1988, and after finished her study in 1991, she was employed as a chief physician in Fujian Provincial Institute of Cardiovascular Diseases for two years. In 1993 she studied under the indoctrination of Prof. CHEN Ke-ji, majoring in cardiovascular diseases in the China Academy of Chinese Medical Sciences (CACMS) and got the doctoral degree in July 1996. In 1998, she finished the post-doctorate research on the prevention and treatment of senile dementia in Beijing University of Chinese Medicine.Since then, she took charge in managerial work as the assistant director of department of cardiovascular diseases of Xiyuan Hospital of CACMS and the director of department of scientific research supervisal in CACMS, meanwhile, as a Prof. of Medicine, the tutor of doctoral students on integrated traditional Chinese and Western medicine (TCM-WM)of CACMS.

  11. Open Access Integrated Therapeutic and Diagnostic Platforms for Personalized Cardiovascular Medicine

    Directory of Open Access Journals (Sweden)

    Todd T. Schlegel

    2013-08-01

    Full Text Available It is undeniable that the increasing costs in healthcare are a concern. Although technological advancements have been made in healthcare systems, the return on investment made by governments and payers has been poor. The current model of care is unsustainable and is due for an upgrade. In developed nations, a law of diminishing returns has been noted in population health standards, whilst in the developing world, westernized chronic illnesses, such as diabetes and cardiovascular disease have become emerging problems. The reasons for these trends are complex, multifactorial and not easily reversed. Personalized medicine has the potential to have a significant impact on these issues, but for it to be truly successful, interdisciplinary mass collaboration is required. We propose here a vision for open-access advanced analytics for personalized cardiac diagnostics using imaging, electrocardiography and genomics.

  12. Open Access Integrated Therapeutic and Diagnostic Platforms for Personalized Cardiovascular Medicine

    Science.gov (United States)

    Gladding, Patrick A.; Cave, Andrew; Zareian, Mehran; Smith, Kevin; Hussan, Jagir; Hunter, Peter; Erogbogbo, Folarin; Aguilar, Zoraida; Martin, David S.; Chan, Eugene; Homer, Margie L.; Shevade, Abhijit V.; Kassemi, Mohammad; Thomas, James D.; Schlegel, Todd T.

    2013-01-01

    It is undeniable that the increasing costs in healthcare are a concern. Although technological advancements have been made in healthcare systems, the return on investment made by governments and payers has been poor. The current model of care is unsustainable and is due for an upgrade. In developed nations, a law of diminishing returns has been noted in population health standards, whilst in the developing world, westernized chronic illnesses, such as diabetes and cardiovascular disease have become emerging problems. The reasons for these trends are complex, multifactorial and not easily reversed. Personalized medicine has the potential to have a significant impact on these issues, but for it to be truly successful, interdisciplinary mass collaboration is required. We propose here a vision for open-access advanced analytics for personalized cardiac diagnostics using imaging, electrocardiography and genomics. PMID:25562653

  13. Training requirements for chemists in radiotracer development for nuclear medicine

    International Nuclear Information System (INIS)

    This panel was organized to address the current and anticipated future shortage of chemists with advanced training to fill positions in the nuclear medicine field. Although hard data and statistics are difficult to acquire, we will attempt to highlight the impact of chemistry on nuclear medicine and to describe the growth of the field which has led to an increasing need for chemists resulting in the current manpower shortage. We also will make recommendations for attracting Ph.D. chemists to careers in nuclear medicine research and possible mechanisms for postgraduate training. Solving this problem and establishing a long term committment and mechanism for advanced training is critically important to meet the current needs of the profession and to assure future growth and innovation. 3 tabs

  14. Tomography in nuclear medicine. Proceedings of an international symposium

    International Nuclear Information System (INIS)

    Single photon emission computed tomography (SPECT) is currently being used universally in clinical practice, while positron emission tomography (PET), originally developed as a technique for research, has also gradually moved from the research laboratory to the clinical environment. However, there are significant differences in nuclear medicine capabilities, especially in tomography, between developed and developing countries. The present status and future prospects of nuclear medicine tomography were the main topics of discussion at this latest international symposium, organized by the IAEA in co-operation with the World Health Organization and held in Vienna from 21 to 25 August 1995. The purpose of the meeting was to share experience and information on new developments and clinical applications of two promising tomographic techniques: SPECT and PET. Eight invited papers and 34 regular papers from 23 countries were presented. In addition, there was a panel discussion on the future and direction of tomography in nuclear medicine for developing countries. Refs, figs, tabs

  15. Imaging technologies for nuclear medicine offering superior functional diagnosis

    International Nuclear Information System (INIS)

    The nuclear medicine examination is a diagnostic procedure in which organ functions, such as metabolism, blood flow, and neurotransmission, are visualized utilizing radioisotope (RI) tracers. It is a type of molecular imaging, in which RI tracers reflect biological functions on a molecular level. To obtain images with high diagnostic accuracy, Toshiba Medical Systems Corporation has developed the following sophisticated technologies for nuclear medicine: a radiation measurement technology with a high time resolution of several hundred picoseconds, a quantification method that can compensate for Compton scattering and photoelectric effects, and an image reconstruction technology. We are supplying proprietary nuclear medicine systems incorporating these technologies with the objectives of decreasing the patient burden and contributing to hospital management efficiency through reduction of radiation doses and shortening of examination times. (author)

  16. Dynamic functional studies in nuclear medicine in developing countries

    International Nuclear Information System (INIS)

    The Proceedings document some of the trials and tribulations involved in setting up nuclear medicine facilities in general and specifically as regards nuclear medicine applications for the diagnosis of the diseases prevalent in the less developed countries. Most of the 51 papers deal with various clinical applications of dynamic functional studies. However, there was also a session on quality control of the equipment used, and a panel discussion critically looked at the problems and potential of dynamic studies in developing countries. This book will be of interest and use not only to those practising nuclear medicine in the developing countries, but it may also bring home to users in developed countries how ''more can be done with less''. Refs, figs and tabs

  17. Report: dosimetry of diagnostic exams in nuclear medicine

    International Nuclear Information System (INIS)

    A compilation about dosimetry of diagnosis explorations in nuclear medicine is presented in this issue. Dosimetry tables of the different radiopharmaceuticals used in nuclear medicine give indications on absorbed and efficient doses according the patients age from one year to adult age. The doses received by a fetus during a lung scintigraphy realized for the pregnant woman susceptible to suffer of pulmonary emboli is presented. A table of efficient doses for the infants until the age of six months for the principal scintigraphy explorations realized in nuclear medicine are given. A chapter of theoretical headlines is devoted to dosimetry and the calculations methods of absorbed and efficient doses in function of patients age. A short chapter concerns the recommendations to explore nursing mothers by scintigraphy. A last chapter treats the efficient doses received during explorations using ionizing radiations in radiology and their place in annual natural irradiation scale. (N.C.)

  18. Traceability of radionuclide calibrators measurements in nuclear medicine

    International Nuclear Information System (INIS)

    In nuclear medicine, the administered doses of the radiopharmaceutical are expressed through the amount of radioactivity contained in the drug. The measurement of this activity, performed using a radionuclide calibrator, is of the utmost importance to guarantee the national and international comparability of clinic results and the radiological safety of the patient. In this paper, the transferring of the becquerel unit to the radionuclide calibrators employed in the nuclear medicine practice in Cuba is detailed. The obtained results with an in situ calibration service, which is based on the direct comparison with standards of the specific measured radionuclides, are presented. Outcomes of international and national measurement comparisons are shown. They validate the uncertainty estimates of the calibration coefficients installed in the instruments for measurements of 99Tcm , 131I and 201Tl, the main gamma emitters that have been used in Cuban nuclear medicine. (author)

  19. Nuclear medicine techniques and magnetic resonance imaging in coronary artery disease

    International Nuclear Information System (INIS)

    Primary modalities for non-invasive imaging of coronary artery disease (CAD) and related disorders include nuclear medicine techniques and magnetic resonance imaging (MRI). Nuclear medicine has contributed greatly to the diagnosis of CAD and the assessment of the extent of functional abnormalities. Tallium-201 has a long history as a perfusion agent and is currently also used to study myocardial viability. Developments in radiopharmaceutical chemistry has provided us with 99mTc-labelled agents with better counting statistics and qualities for SPECT-imaging. Other radiopharmaceuticals allow insight in metabolic disorders, hypoxia and disturbance of the adrenergic system of the myocardium. MRI has many unique applications is cardiovascular diseases. this imaging technique provides excellent structural information and, during ECG triggering, fine display of left ventricular function. Current development using intravascular contrast agents will soon lead to the possibility to the evaluate myocardial perfusion. Improved techniques to evaluate coronary artery anatomy and flow are currently under clinical study. Although cardiac MRI is an exciting new tool with great potential for the diagnosis of CAD it is presently not considered a valid alternative for nuclear medicine imaging techniques. Important developments in the next lustrum may change this view

  20. Prediabetes and cardiovascular risk alert programs - useful tools for preventing diabetes mellitus and cardiovascular events in primary medicine.

    Science.gov (United States)

    Virgolici, Horia; Virgolici, Bogdana; Purcarea, Victor

    2015-01-01

    We propose alert programs, made in Excel using VBA, for general practitioners, in order not to miss the diagnosis of prediabetes and cardiovascular risk factors for their patients and to improve their management. PMID:25991138

  1. Generation and Assessment of Functional Biomaterial Scaffolds for Applications in Cardiovascular Tissue Engineering and Regenerative Medicine.

    Science.gov (United States)

    Hinderer, Svenja; Brauchle, Eva; Schenke-Layland, Katja

    2015-11-18

    Current clinically applicable tissue and organ replacement therapies are limited in the field of cardiovascular regenerative medicine. The available options do not regenerate damaged tissues and organs, and, in the majority of the cases, show insufficient restoration of tissue function. To date, anticoagulant drug-free heart valve replacements or growing valves for pediatric patients, hemocompatible and thrombus-free vascular substitutes that are smaller than 6 mm, and stem cell-recruiting delivery systems that induce myocardial regeneration are still only visions of researchers and medical professionals worldwide and far from being the standard of clinical treatment. The design of functional off-the-shelf biomaterials as well as automatable and up-scalable biomaterial processing methods are the focus of current research endeavors and of great interest for fields of tissue engineering and regenerative medicine. Here, various approaches that aim to overcome the current limitations are reviewed, focusing on biomaterials design and generation methods for myocardium, heart valves, and blood vessels. Furthermore, novel contact- and marker-free biomaterial and extracellular matrix assessment methods are highlighted. PMID:25778713

  2. Festschrift. The Institute of Nuclear Medicine. 50 years

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    The Institute of Nuclear Medicine, founded in 1961, celebrates with this Festschrift, its Golden Jubilee. It has been a remarkable 50 years of progress of the radionuclide tracer methodology. From initial, physiology based experimentation, a full independent medical discipline evolved, and with it, a comprehensive clinical service. Diagnosis and Treatment with radiotracers have established the basis for Nuclear Medicine. Technological advances have permeated the field like none other, its multidisciplinary character and its translational research are embedded in the history of the Institute and its success. Recent and latest advances in the field promise a future as bright as has been witnessed and documented in the last 50 years.

  3. Radiation dose due to nuclear medicine practice in Ghana

    International Nuclear Information System (INIS)

    The Ghanaian population who underwent nuclear medicine procedures within the period 1990-1993 has been characterized by age and sex. Males received 40% of the procedures while females received 60%. About two-thirds of the procedures annually were performed on patients over the age of thirty years. The mean annual collective dose was found to be 2.7 man-Sv during the four-year period examined. This translated into a per capita dose of 0.2μSv per year for nuclear medicine procedures over the period. (author). 4 refs.; 6 tabs

  4. Survival and development of nuclear medicine in Western China

    International Nuclear Information System (INIS)

    This essay discusses how to develop departments of nuclear medicine in mountainous areas in West China. The developments need the leaders' supports, doctors' understanding and patients' trust. And it is also very important to improve doctors' skills of diagnosis and treatment, and the management of medical quality, and overcome inconveniences in transportation and communication. At the same time, more projects such as radionuclide imaging, radioimmunoassay, radionuclide treatment and personnel training should be also key contents in the development of departments of nuclear medicine in these areas

  5. 5. Measuring and evaluation methods in nuclear medicine

    International Nuclear Information System (INIS)

    Conventional radiation detectors used in nuclear medicine are briefly characterized. They include scintillation counters, gas ionization detectors, and semiconductor detectors. Their basic parameters and software characteristics are given. Instrumentation for in vitro measurement (detectors with scintillation crystals, with liquid scintillators) and in vivo measurements (for functional and scintigraphic examination) is described. Applications of computer techniques in nuclear medicine for the processing of in vivo examination results and of the results of radiosaturation analysis (in vitro) are outlined. The principles of computed emission tomography are explained. (Z.S.). 18 figs., 12 refs

  6. Radiation burden to hands of nuclear medicine personnel

    International Nuclear Information System (INIS)

    Radiation burden is discussed imposed to the hands of nuclear medicine personnel handling 99Mo-sup(99m)Tc generators, imported from the GDR and Great Britain. The results are compared with available foreign data. Routine monitoring of the hands of nuclear medicine personnel is recommended. Suitable types of dosimeters for such measurements are briefly discussed. The need is stressed of better care paid in periodic preventive examinations to the finger skin of those personnel, whose hands come in contact with radiopharmaceuticals during production or application

  7. Benefit/risk considerations in diagnostic nuclear medicine

    International Nuclear Information System (INIS)

    The potential radiation risk carried out by diagnostic nuclear medicine has to be compared with the potential diagnostic and/or therapeutic benefit. An undifferentiated consideration of collective doses and risks is inappropriate. On the contrary, several factors have to be considered: The age of the patients, the prevalence of pathological test results, and the potential benefit from the diagnosis. This paper presents statistical data and individual examples. In many cases benefit exceeds risk substantially. On the other hand in some cases restrictions of diagnostic radiology or nuclear medicine should be considered. (orig.)

  8. Research advancements and applications of carboranes in nuclear medicinal chemistry

    International Nuclear Information System (INIS)

    Because of their uniquely high thermal and chemical stabilities, carboranes have become a subject of study with high interest in the chemistry of supra molecules, catalysts and radiopharmaceuticals. In recent years, the role of carboranes in nuclear medicinal chemistry has been diversified, from the traditional use in boron neutron capture therapy (BNCT), to the clinical applications in molecular radio imaging and therapy. This paper provides an overview of the synthesis and characterization of carboranes and their applications in nuclear medicinal chemistry, with highlights of recent key advancements in the re- search areas of BNCT and radio imaging. (authors)

  9. Technical guide to nuclear medicine. 3. rev. ed.

    International Nuclear Information System (INIS)

    The book transmits in a clear way the present theoretical and practical knowledge necessary for the application of nuclear-medical methods. This covers the basic knowledge in physics, metrology, data processing, and special physiological knowledge necessary for nuclear medicine. Radiobiological fundaments are given as they are required to understand nuclear-medical therapy and for the rules of radiation protection. Function and localisation diagnostics are dealt with in separate chapters but from the same points of view. In numerous detailed examples the examination methods most frequently used are explained. In a special general chapter, the increasing importance of nuclear-medical in-vitro tests is paid attention to. (orig./HP)

  10. Assessment of knowledge of general practitioners about nuclear medicine

    International Nuclear Information System (INIS)

    Nuclear medicine is an important department in most of scientific hospitals in the world. Rapid improvement in the filed of nuclear medicine needs continuing education of medical students. We tried to evaluate the knowledge of general practitioners in the flied of nuclear medicine, hoping that this study help mangers in accurate planning of teaching programs. Methods and materials: We prepared a questionnaire with 14 questions regarding applications of nuclear medicine techniques in different specialities of medicine. We selected questions as simple as possible with considering the most common techniques and best imaging modality in some disease. One question in nuclear cardiology, one in lung disease, two questions in thyroid therapy, another two in gastrointestinal system, two in genitourinary system and the last two in nuclear oncology. Also 4 questions were about general aspects of nuclear medicine. We have another 4 questions regarding the necessity of having a nuclear medicine subject during medical study, the best method of teaching of nuclear medicine and the preferred method of continuing education. Also age, sex, graduation date and university of education of all subjects were recorded. Results: One hundred (General practitioners) were studied. including, 58 male and 42 female with age range of 27-45 years did . About 60% of cases were 27-30 years old and 40 cases were older than 40. Seventy two cases were graduated in the last 5 years. Mashad University was the main university of education 52 cases with Tehran University (16 cases) and Tabriz University (6 cases) in the next ranks. Also 26 cases were graduated from other universities. From four questions in the field of general nuclear nedione 27% were correctly answered to all questions, 37% correctly answered two questions and 10% had correct answered only one question. No correct answer was noted in 26% . correct answer was noted in 80% the held of nuclear cardiology and in 72% in the field of lung

  11. Education in nuclear physics, medical physics and radiation protection in medicine and veterinary medicine

    International Nuclear Information System (INIS)

    Education in Nuclear Physics, Medical Physics and Radiation Protection in medicine and veterinary medicine studies on Belgrade University is an integral part of the curriculum, incorporated in different courses of graduate and post-graduate studies. During graduate studies students get basic elements of Nuclear Physics through Physics and/or Biophysics courses in the 1st year, while basic knowledge in Medical Physics and Radiation Protection is implemented in the courses of Radiology, Physical Therapy, Radiation Hygiene, Diagnostic Radiology and Radiation Therapy in the 4th or 5th year. Postgraduate studies offer MSc degree in Radiology, Physical Therapy, while courses in Nuclear Physics, Nuclear Instrumentation, Radiation Protection and Radiology are core or optional. On the Faculty of Veterinary Medicine graduated students may continue their professional education and obtain specialization degree in Radiology, Physical Therapy or Radiation Protection. On the Faculty of Medicine there are specialization degrees in Medical Nuclear Physics. Still, a closer analysis reveals a number of problems both from methodological and cognitive point of view. They are related mostly to graduate students ability to apply their knowledge in practise and with the qualifications of the educators, as those engaged in graduate studies lack basic knowledge in biological and medical sciences, while those engaged in post graduate studies mostly lack basic education in physics. Therefore, a reformed curricula resulting from much closer collaboration among educators, universities and professional societies at the national level should be considered. (author)

  12. Dictionary of radiation protection, radiobiology and nuclear medicine

    International Nuclear Information System (INIS)

    Radiation protection, including aspects of radiobiology, nuclear medicine, and nuclear legislation, has an important role within nuclear research and the use of radioactive materials. Radiation protection comprises all measures and efforts to prevent the unwanted distribution and negative influence of ionizing radiation, especially where the human organism and the living environment are involved. The increasing role of radiation protection is reflected by the foundation of institutes in all industrial countries to control such radiant energy and prevent radiation damage. Nowadays ionizing radiation is employed on a large scale for basic investigations in biochemistry, molecular biology and genetics, in soil tests, fertilization problems and pest control in agriculture, as well as for medicinal diagnoses and therapy. This dictionary is a thematic enlargement of the four-language 'Dictionary of Nuclear Engineering', compiled by the same author. It comprises about 12,000 terms in each language. (orig.)

  13. Nuclear medicine and radiologic imaging in sports injuries

    International Nuclear Information System (INIS)

    This comprehensive book describes in detail how nuclear medicine and radiology can meet the needs of the sports medicine physician by assisting in precise diagnosis, clarification of pathophysiology, imaging of treatment outcome and monitoring of rehabilitation. Individual sections focus on nuclear medicine and radiologic imaging of injuries to the head and face, spine, chest, shoulder, elbow and forearm, wrist and hand, pelvic region, knee, lower leg, ankle and foot. The pathophysiology of sports injuries frequently encountered in different regions of the body is described from the perspective of each specialty, and the potential diagnostic and management benefits offered by the new hybrid imaging modalities - SPECT/CT, PET/CT, and PET/MRI - are explained. In addition, a range of basic and general issues are addressed, including imaging of the injuries characteristic of specific sports. It is hoped that this book will promote interdisciplinary awareness and communication and improve the management of injured recreational or elite athletes.

  14. Radioprotection in nuclear medicine department of 'Porto Alegre Clinical Hospital'

    International Nuclear Information System (INIS)

    The use of ionizing radiation in medicine allows great benefits. Nuclear Medicine uses ionizing radiation for medical diagnostic, such as: tumor, cancer, and dysfunctions location. However the use of ionizing radiation must be controlled in order to avoid likely biological effects in human beings. In order to extremely minimize that these effects appear, the Medical Physics Department of the Porto Alegre Clinical Hospital has implemented some procedures to assure that handling and use of radioactive material are in a safe way. This preoccupation is considered in all the places of nuclear medicine sector since the moment when the radioactive material is brought into including its manipulation and retirement, the exam process being accompanied. (authors). 4 refs

  15. Nuclear medicine and radiologic imaging in sports injuries

    Energy Technology Data Exchange (ETDEWEB)

    Glaudermans, Andor W.J.M. [Groningen Univ. (Netherlands). Dept. of Nuclear Medicine and Molecular Imaging; Dierckx, Rudi A.J.O. [Groningen Univ. (Netherlands). Dept. of Nuclear Medicine and Molecular Imaging; Ghent Univ. (Belgium); Gielen, Jan L.M.A. [Antwerp Univ. Hospital, Edegem (Belgium). Dept. of Radiology; Antwerp Univ. Hospital, Edegem (Belgium). Dept. of Sports Medicine; Antwerp Univ. Hospital, Edegem (Belgium). Dept. of Medicine; Zwerver, Johannes (ed.) [Groningen Univ. (Netherlands). Center for Sports Medicine

    2015-10-01

    This comprehensive book describes in detail how nuclear medicine and radiology can meet the needs of the sports medicine physician by assisting in precise diagnosis, clarification of pathophysiology, imaging of treatment outcome and monitoring of rehabilitation. Individual sections focus on nuclear medicine and radiologic imaging of injuries to the head and face, spine, chest, shoulder, elbow and forearm, wrist and hand, pelvic region, knee, lower leg, ankle and foot. The pathophysiology of sports injuries frequently encountered in different regions of the body is described from the perspective of each specialty, and the potential diagnostic and management benefits offered by the new hybrid imaging modalities - SPECT/CT, PET/CT, and PET/MRI - are explained. In addition, a range of basic and general issues are addressed, including imaging of the injuries characteristic of specific sports. It is hoped that this book will promote interdisciplinary awareness and communication and improve the management of injured recreational or elite athletes.

  16. Radiopharmacy contamination in nuclear medicine - a survey report

    International Nuclear Information System (INIS)

    To conduct the radiation survey of the category IV Nuclear Medicine department and to further measure and compare the level of loose contamination in areas with high levels of exposure at two different time points (morning and evening) using wipe test

  17. Code of practice for radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    In aim of this study was to develop a draft for a new code practice for radiation protection in nuclear medicine that meets the current relevant international recommendation. The draft includes the following main fields: methods of radiation protection for workers, patients and public. Also, the principles of safe design of nuclear medicine departments, quality assurance program, proper manipulation of radiation sources including radioactive waste and emergency preparedness and response. The practical part of this study includes inspections of three nuclear medicine departments available in Sudan so as to assess the degree of compliance of those departments with what is stated in this code. The inspection missions have been conducted using a checklist that addresses all items that may affect radiation raincoat issues in addition to per formin area radiation monitoring around the installation of the radioactive sources. The results of this revealed that most of the departments do not have effective radiation protection program which in turn could lead to unnecessary exposure to patients, public and workers. Finally, some recommendations are given that - if implemented - could improve the status of radiation protection in nuclear medicine department. (Author)

  18. Nuclear Medicine Technology: A Suggested Two-Year Curriculum Manual.

    Science.gov (United States)

    Hunter, David

    This curriculum guide prescribes an educational program for training nuclear medicine technologists. Following a brief section on program development, the curriculum is both outlined and presented in detail. For each of the 44 courses, the following information is given: (1) sequential placement of the course in the curriculum; (2) course…

  19. Nuclear medicine imaging in the evaluation of endocrine hypertension

    OpenAIRE

    Punit Sharma; Rakesh Kumar

    2012-01-01

    Endocrine hypertension forms a small (< 5%) but curable subset of patients with hypertension. Common endocrine causes of hypertension include pheochromocytoma, Cushing's syndrome, primary hyperaldosteronism, and thyroid disorders. Nuclear medicine imaging plays an important role in evaluation of patients with endocrine hypertension. It has established role in patients of pheochromocytoma/paraganglioma, Cushing's syndrome, aldosteronism, and thyroid disorders. We present a brief overview of ro...

  20. An internet-based teaching file on clinical nuclear medicine

    International Nuclear Information System (INIS)

    Objective: The goal of this project was to develop an internet-based interactive digital teaching file on nuclide imaging in clinical nuclear medicine, with the capability of access to internet. Methods: On the basis of academic teaching contents in nuclear medicine textbook for undergraduates who major in nuclear medicine, Frontpage 2000, HTML language, and JavaScript language in some parts of the contents, were utilized in the internet-based teaching file developed in this study. Results: A practical and comprehensive teaching file was accomplished and may get access with acceptable speed to internet. Besides basic teaching contents of nuclide imagings, a large number of typical and rare clinical cases, questionnaire with answers and update data in the field of nuclear medicine were included in the file. Conclusion: This teaching file meets its goal of providing an easy-to-use and internet-based digital teaching file, characteristically with the contents instant and enriched, and with the modes diversified and colorful

  1. Mathematic filters and digital processing in nuclear medicine

    International Nuclear Information System (INIS)

    The mathematic filters used in nuclear medicine were evaluated. Tomographic processing of a Jaszczak phantom, using separately Hanning, Butterworth and Wiener filters were presented. For each type of filter were made simulation, where the cut frequency and extenuation grade values were changed. (C.G.C.)

  2. Population effective collective dose from nuclear medicine examination in Cuba

    International Nuclear Information System (INIS)

    In an attempt to estimate the effective collective dose imparted to the population of Camagueey-Ciego de Avila territory (Cuba)), we have made use of the statistics from nuclear medicine examinations given to a population of 1.1 million inhabitants for the years 1995-1999. The average annual frequency of examinations was estimated to be 3.82 per 1000 population. The results show that nuclear medicine techniques of thyroid imaging with 43.73% and thyroid uptake with 43.36% are the main techniques implicated in the relative contribution to the total annual effective collective dose, which averaged 54.43 man Sv for the studied period. Radiation risks for the Camagueey-Ciego de Avila population caused by nuclear medicine examinations in the period studied were calculated: the total number of fatal and non-fatal cancers was 16.33 and the number of serious hereditary disturbance was 3.54 as a result of 21,073 nuclear medicine procedures, corresponding to a total detriment of one case per thousand examinations. (authors)

  3. Symposium on nuclear particle accelerators in medicine: abstracts

    International Nuclear Information System (INIS)

    This symposium deals with the cyclotron production of radiopharmaceuticals and the application of radionuclides and -pharmaceuticals produced this way. The use of positron emitters in nuclear medicine medical physics and radiobiology are discussed as well as radiotherapy and all the aspects of neutron radiation and dosimetry of neutron therapy

  4. Hardware and software for image acquisition in nuclear medicine

    International Nuclear Information System (INIS)

    A system for image acquisition and processing in nuclear medicine is presented, including the hardware and software referring to acquisition. The hardware is consisted of an analog-digital conversion card, developed in wire-wape. Its function is digitate the analogic signs provided by gamma camera. The acquisitions are made in list or frame mode. (C.G.C.)

  5. Quality approach in hygiene in a nuclear medicine service

    International Nuclear Information System (INIS)

    The activities of nuclear medicine, by their constraints of radiation protection, present difficulties for rules of hygiene protocols. Considering the particular risks of certain techniques, the approach brings to the fore the compromise between radiation protection and hygiene and to adapt the recommendations to local specificities. (N.C.)

  6. 20. Brazilian congress on biology and nuclear medicine. Abstracts

    International Nuclear Information System (INIS)

    Several aspects concerning the use of nuclear medicine in cardiology, oncology, neurology, endocrinology among other areas are studied. Various topics related to diagnosis and treatment of diseases are presented, e.g. radiotracers use, radiopharmaceuticals (mainly associated with technetium 99), development and standardization of radionuclides, structural chemical analysis, metabolism, biological functions. The scintiscanning is the most reported diagnostic technique

  7. Dictionary/handbook of nuclear medicine and clinical imaging

    International Nuclear Information System (INIS)

    This book covers the following topics: Fundamentals of English medical etymology, Abbreviations, acronyms, symbols, denotations, and signs commonly used or defined in the dictionary, Characteristics of the elements, Characteristics of practicable radioisotopes and of selected radionuclides commonly used in nuclear medicine, Properties and production of radionuclides, Radioactive decay, Radiopharmaceuticals, and Radiation dosimetry

  8. Closing the gap between theory and practice in Nuclear Medicine

    International Nuclear Information System (INIS)

    Aim: The ultimate goal for any clinical teaching program is to have students who demonstrate clinical competence. The Nuclear Medicine Technologist like any health professional should graduate from their course: attaining a defined standard of core knowledge; demonstrating appropriate behaviour for the workplace; and, achieving a predetermined level of clinical skill. In the University of Sydney Nuclear Medicine course, revisions were made to the Clinical Education assessment tools to create a more incremental approach and define competencies that required a higher level of achievement. Nuclear Medicine theory delivery was changed to create a more contextual environment where the student was better prepared for the workplace. The aim of this study is firstly to analyse the relationship between assessment of contextual theory and assessment of clinical practice. A secondary aim is to investigate any relationship between individual clinical assessment tools. Clinical assessment tools include: clinical competencies; observed clinical skills examinations (OSCE); clinical and university supervisor assessments; and assignments. Nuclear Medicine theory assessment tools include: problem oriented teamwork presentations; assignment; and written examination. Method: Correlation of the students' overall marks in the subjects' Nuclear Medicine theory and Clinical Education in the years 2000 and 2001 was undertaken using SPSS. Correlation of the students' scores in the individual clinical assessment tools: Clinical Supervisor to University supervisor; Clinical Supervisor to OSCE; and University Supervisor to OSCE, was completed for the years 2000 and 2001. Results: A statistically significant correlation was found for the students' marks in Nuclear Medicine theory and Clinical Education for the same year. The University and Clinical Supervisors' results significantly correlated for all years. Correlation between the individual assessment tools used in Clinical Education was not

  9. Pathway to the contemporary innovations in nuclear medicine

    International Nuclear Information System (INIS)

    Full text: Introduction: A brief overview of the long road of fundamental discoveries, innovations and their improvement and development of modern clinical nuclear medicine from the discovery of X- rays by Wilhelm Conrad Roentgen (1895), the phenomenon of radioactivity by Antoine Henry Becquerel (1896), the natural radioactivity and discovering of radium and polonium by Marie and Pierre Curie (1897) discovering of radioactive decay (alpha, beta particles and gamma photons) and the term 'half-life' by Ernest Rutherford (1900), discovering of artificial radioactivity with the possibility of obtaining new radionuclides by Irena and Frederick Joliot-Curie (1932 ). What you will learn: Important place in nuclear medicine radiochemistry is discovering of routine production and clinical use of the most appropriate radiopharmaceuticals (RFs) specific for the given diagnostic and therapy. Such are radioactive Gold, Mercury, Selenium, radionuclides of Iodine (131I-NaI, 123I), RFs marked with 99mTc, 111In, 67Ga, more widely applicable short-lived positron emitters 18F, 11C 15O, 13N, 68Ga and their radiopharmaceutical forms for diagnostic. For metabolic radionuclide therapy for many years 198Au has been used in omentum carcinose, and 32P for bone metastases, polycythemia vera and 131I-NaI as a gold standard in treatment of differentiated thyroid carcinoma and some benign hyperfunctional conditions. Today 89Sr, 153Sm, 186Re are applied for pain control in metastatic bone disease. 90Y-ibritumomab tiuxetan (Zevalin) and 131I-tositumomab (Bexxar) are used for specific treatment of lymphomas. Discussion: Starting with the first diagnostic nuclear medicine study performed by Hermann Blumgart and Otto Jens in 1926, passing through the first static display of RFs biodistribution in 50s and faster static and dynamic images of the proposed by Hal Anger gamma camera and PET imaging by Gordon Brownell, nuclear medicine metabolic images improved with more precise functional and structural

  10. The required dose of imaging systems - nuclear medicine

    International Nuclear Information System (INIS)

    The required dose of imaging systems in nuclear medicine is based upon the statistical properties of radioactive decay. In contrast to the absorbed dose, the radioactivity can be directly and easily measured. The International Commission on Radiological Protection (ICRP) has developed the concept of effective dose. Based on this concept, radiation exposure by nuclear medicine and radiodiagnostic procedures can be compared to the natural radiation burden. In addition, the hypothetical risk associated with exposure to ionizing radiation can be estimated and compared to that in daily life. Radiation exposure in nuclear medicine procedures including PET remain within the limits of annual natural radiation exposure (1-6 mSv). The overall risk of any diagnostic procedure employing ionizing radiation in radiology appears to be negligible. The activity used for procedures in nuclear medicine is a compromise between radiation safety and image quality. A recent representative evaluation revealed that the average activity used for nuclear medicine procedures in Germany is lower than in other European states. While for most adult procedures a standard dose is given, the accepted method for children is the weight method. Any procedure employing ionizing radiation is usually performed only if alternative diagnostic imaging modalities sich as ultrasound and MRI cannot answer a specific test question appropriately. In addition to the latter, there are several ways to minimize radiation exposure. The most important way of assuring quality in any procedure is a strong quality-control program. Furthermore, comprehensive knowledge encompassing the indications for a study, the technical aspects of its acquisition and processing, and the final interpretation of its results are of great importance. Finally, it is known that prolonged data acquisition will result in improved image quality: however, this is clearly limited by the acceptance of the patient. (orig.)

  11. A European network for nuclear medicine and radiotherapy. EMIR

    International Nuclear Information System (INIS)

    Nuclear medicine and radiotherapy make a vital contribution to the diagnosis and treatment of major disease. This role is likely to expand with new developments including availability of new medical isotopes. A European network (EMIR) was initiated in 2001 by the Joint Research Centre (JRC) of the European Commission, to identify and solve difficulties that constrain nuclear medicine and radiotherapy development in Europe and facilitate closer interdisciplinary collaboration. Participating organisations include the main European associations of medical radiation specialists, radiopharmaceutical/radioisotope producers, nuclear research reactor institutions, research organizations and the JRC. The steering committee established task groups focusing on eight key areas for development. Liaison with non-European organizations will be encouraged. (author)

  12. The radiological protection in the nuclear medicine practice

    International Nuclear Information System (INIS)

    The nuclear medicine practice dates of the 1950 years, in this work the achievements reached as regards radiological protection are shown, although even lack a lot to make, the doses for the occupationally exposed personnel have decreased with lapsing of the years, thanks to the perception of the nuclear physicians to improve the administration techniques of the radioactive material, the decrease of administered activity and the unit doses use among the most remarkable advances. The changes in the equipment s technology to quantify the activity to administer, detection systems and image formation have demanded the development of the new professionals of the nuclear medicine that allows give protection to the patient. This improvement needs to consolidate with the appropriate normative development, the involved personnel qualification and the methods and procedures actualization to improve the protection of the occupationally exposed personnel, the public, the environment and the patient. (Author)

  13. Society of Nuclear Medicine--57th annual meeting.

    Science.gov (United States)

    Searle, Ben

    2010-08-01

    The 57th Annual Meeting of the Society of Nuclear Medicine, held in Salt Lake City, UT, USA, included topics covering new developments in imaging agents and radiopharmaceutical therapies in the field of nuclear medicine. This conference report highlights selected presentations related to imaging of the brain, the prediction of heart disease, and the detection and treatment of various cancers. Investigational drugs discussed include TF-2 plus [68Ga]IMP-288 and TF-2 plus [111In]IMP-288 (both Immunomedics Inc), [11C]PBR-170 (Royal Prince Alfred Hospital/Australian Nuclear Science & Technology Organization), [11C]LY-2795050 (Eli Lilly & Co), yttrium (90Y) clivatuzumab tetraxetan (Garden State Cancer Center/Immunomedics Inc), [18F]LMI-1195 (Lantheus Medical Imaging Inc), fluciclovine (18F) (GE Healthcare/Nihon Medi-Physics Co Ltd), [99mTc]MIP-1340 and [99mTc]MIP-1407 (both Molecular Insight Pharmaceuticals Inc). PMID:20721816

  14. Therapeutic Applications of Monte Carlo Calculations in Nuclear Medicine

    CERN Document Server

    Sgouros, George

    2003-01-01

    This book examines the applications of Monte Carlo (MC) calculations in therapeutic nuclear medicine, from basic principles to computer implementations of software packages and their applications in radiation dosimetry and treatment planning. It is written for nuclear medicine physicists and physicians as well as radiation oncologists, and can serve as a supplementary text for medical imaging, radiation dosimetry and nuclear engineering graduate courses in science, medical and engineering faculties. With chapters is written by recognised authorities in that particular field, the book covers the entire range of MC applications in therapeutic medical and health physics, from its use in imaging prior to therapy to dose distribution modelling targeted radiotherapy. The contributions discuss the fundamental concepts of radiation dosimetry, radiobiological aspects of targeted radionuclide therapy and the various components and steps required for implementing a dose calculation and treatment planning methodology in ...

  15. Nuclear data for medicine and electronics

    International Nuclear Information System (INIS)

    Fast-neutron cancer therapy is now routinely performed at about a dozen facilities worldwide. Typical neutron energies for treatment are up to 70 MeV. Lately, it has been recognized that cosmic-ray neutrons, with energies up to many GeV, give significant dose contributions to airplane personnel. In fact, airplane personnel are the category, which receives the largest doses in civil work. These cosmic-ray neutrons also create a reliability problem in modern electronics. A neutron can cause a nuclear reaction inside or near a chip, thus releasing free charge, which in turn could, e.g., flip the memory content or change the result of a logical operation. For all these applications, improved knowledge of the underlying nuclear physics is of major importance. The MEDLEY setup, which has been extensively used for ADS related work, has been used for measurements of cross sections related to biomedicine and electronics reliability. Simulations of single-event upsets are described as well as accelerated device testing activities at neutron beams. (orig.)

  16. The connected health of cardiovascular medicine: current status and future directions

    OpenAIRE

    Ansary, A.; Azuma, A; Komatireddy, R.; Barrett, P.M.

    2013-01-01

    The technologies of cardiovascular connected health stand to dramatically alter the management and prevention of cardiovascular disease, a worldwide leading cause of death. The American Heart Association has outlined seven key health metrics including physical activity, adequate blood pressure control, weight and a healthy diet, which lie at the core of cardiovascular disease management. Controlling these metrics has been demonstrated to result in substantial reductions in cardiovascular mort...

  17. 42 CFR 482.53 - Condition of participation: Nuclear medicine services.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Condition of participation: Nuclear medicine... HOSPITALS Optional Hospital Services § 482.53 Condition of participation: Nuclear medicine services. If the hospital provides nuclear medicine services, those services must meet the needs of the patients...

  18. 32. Days of the Nuclear Medicine: Summaries of the lectures and posters

    International Nuclear Information System (INIS)

    The publication has been set up as a abstracts of the conference dealing with nuclear medicine problems. The book consists of the sections: (1) Introduction lectures; (2) Radionuclide diagnostic methods in the oncology; (3) Miscellaneous; (4) Device techniques and physical problems in nuclear medicine; (5) The problems of radiation protection in nuclear medicine; (6) Special programme of the SZP; (7) Poster section

  19. ER-E3 regulation. Minimal instrumentation that must operate nuclear medicine in Cuba

    International Nuclear Information System (INIS)

    The purpose of this regulation is to define the instrumentation that must exist in any institution conducting the practice of nuclear medicine in Cuba. This regulation emphasizes two aspects: The minimum equipment necessary to operate a nuclear medicine laboratory for use 'in vitro' and the minimum equipment required to operate a Nuclear Medicine use 'in vivo'

  20. Radiation exposure to personnel in diagnostic nuclear medicine

    International Nuclear Information System (INIS)

    Investigations under routine conditions concerning the following points; were undertaken. External radiation exposure by Tc-99m to the whole body and to the hands or finger tips of nuclear technicians, physicians and radiochemists; external exposure by Tc-99m to whole body and gonads of nurses in a neurologic intensive care unit with a high frequency of patients who undergo nuclear medicine investigations; the risk to incorporate I-125 in a radioimmunoassay laboratory and in a labelling laboratory. The data show that external radiation exposure from Tc-99m to personnel working in diagnostic nuclear medicine where a total dose of 50 Ci of Tc-99m is applied per year remains far below the maximum permissible doses if the following measures are strictly fullfilled: - Elution, labelling and filling of Tc-99m radiopharmaceuticals only in shielded vials and using long distance working tools. - Application of Tc-99m radiopharmaceuticals using exclusively shielded syringes. - Time of staying next to Tc-99m containing patients as short as possible. Under these conditions, it is unnecessary that personnel who nurses patients with diagnostic nuclear medicine procedure in an intensive care unit are put under radiation control by personnel radiation dosimetry. The internal radiation exposure by inhalation of I-125 which evaporates from radioimmunoassay test tubes is negligible. But there is a risk of external and internal radiation exposure from labelling procedures with radionuclides of iodine, if special protective measures are not carefully considered

  1. Radioactive waste management of the nuclear medicine services

    International Nuclear Information System (INIS)

    Radioisotope applications in nuclear medicine services, for diagnosis and therapy, generate radioactive wastes. The general characteristics and the amount of wastes that are generated in each facility are function of the number of patients treated, the procedures adopted, and the radioisotopes used. The management of these wastes embraces every technical and administrative activity necessary to handle the wastes, from the moment of their generation, till their final disposal, must be planned before the nuclear medicine facility is commissioned, and aims at assuring people safety and environmental protection. The regulatory framework was established in 1985, when the National Commission on Nuclear Energy issued the regulation CNEN-NE-6.05 'Radioactive waste management in radioactive facilities'. Although the objective of that regulation was to set up the rules for the operation of a radioactive waste management system, many requirements were broadly or vaguely defined making it difficult to ascertain compliance in specific facilities. The objective of the present dissertation is to describe the radioactive waste management system in a nuclear medicine facility and provide guidance on how to comply with regulatory requirements. (author)

  2. Quality control of radiopharmaceutical dose calibrators in nuclear medicine unit

    International Nuclear Information System (INIS)

    As part of the program to ensure quality in nuclear medicine unit, in addition to diagnostic procedures, are evaluated activity meters, which is intended to measure the aliquot of radiation of radionuclides and / or radiopharmaceuticals that are administered to patients undergoing diagnostic investigation and / or therapeutic treatment. The good operating condition of dose calibrators is essential to ensure efficiency, safety and reliability of the measurements, once the lack of accuracy in the responses of these equipments can cause significant errors in the activity administered to the patient and may result in poor quality images resulting in the repetition of examis and interference in the successful treatment of the patient. This study aims to, considering the need for constant evaluation of the functioning of the activity meters and the fact that this issue be part the responsibilities of the professional of radiology, perform quality control testing of these instruments in relation to the most recent norm of National Commission of nuclear Energy (CNEN-NN 3:05) in Brazil, that is also in according to the international standards and reference values established during acceptance testing of these instruments in a nuclear medicine service. For this, was made a review of specific literature and the use of barium, cobalt and cesium to the tests in a nuclear medicine service of the state of Pernambuco in Brazil. The obtained results of the specific tests utilized to verify the correct working of the dose calibrators show coherency with the resolutions of the CNEN-NN 3:05 and are also in agreement with the international standards to that the measurement of activities be made with accurate results and thereby contribute to the proper functioning of nuclear medicine service. (authors)

  3. Developing a programme on molecular nuclear medicine. Proceedings of a technical meeting

    International Nuclear Information System (INIS)

    During the last decades, new methodologies have emerged in the molecular nuclear medicine field developed to contribute to the detection, diagnosis, staging and treatment follow-up of human diseases. Single photon emission computed tomography (SPECT) and positron emission tomography (PET) are two examples of this methodology that enabled the study of molecular alterations of cell metabolism in the living subject with non-invasive approaches. 18-fluorine fluorodeoxyglucose positron emission tomography (FDG-PET) is used for many disease diagnoses, differential diagnosis and treatment follow-up. Like FDG, new molecules are also being identified and are promising candidates to be used. Molecular imaging studies the expression of genes involved in the evolution of different diseases. This data has been shown to be a reliable prognostic marker, for accurate diagnosis or for predicting response to treatment in certain cases. The use of molecular imaging in the evaluation of exogenous gene therapy and the study of endogenous gene expression in genetic, neurological, cardiovascular and neoplastic diseases will be of significant importance worldwide in the near future. The use of nuclear medicine and molecular imaging for the study of a disease assures the determination of integral parameters for prognosis and diagnosis. The improvement of the therapeutic decisions involved with the stage and prognosis of a disease will certainly add to the clinical studies that are designed for patient care, treatment and survival improvement. Many efforts have been made and will continue in the future to demonstrate the potential of the association of molecular nuclear technology and nuclear medicine imaging, since it has been shown to be useful and applicable to many important diseases. In addition, molecular biology techniques, such as polymerase chain reaction (PCR) and differential gene expression have added important findings to the study of disease pathogenesis. These techniques have

  4. Nuclear medicine in clinical neurology: an update

    International Nuclear Information System (INIS)

    Isotope scanning using technetium 99m pertechnetate has fallen into disuse since the advent of x-ray computerized tomography. Regional brain blood flow studies have been pursued on a research basis. Increased regional blood flow during focal seizure activity has been demonstrated and is of use in localizing such foci. Cisternography as a predictive tool in normal pressure hydrocephalus is falling into disuse. Positron tomographic scanning is a potent research tool that can demonstrate both regional glycolysis and blood flow. Unfortunately, it is extremely expensive and complex to apply in a clinical setting. With support from the National Institutes of Health, seven extramural centers have been funded to develop positron tomographic capabilities, and they will greatly advance our knowledge of stroke pathophysiology, seizure disorders, brain tumors, and various degenerative diseases. Nuclear magnetic resonance imaging is a potentially valuable tool since it creates tomographic images representing the distribution of brain water. No tissue ionization is produced, and images comparable to second-generation computerized tomographic scans are already being produced in humans

  5. [Nuclear medicine diagnosis of pheochromocytoma with metaiodobenzylguanidine].

    Science.gov (United States)

    Pucar, Dragan; Marković, Stevan

    2002-07-01

    Excess secretion of any of the adrenal cortical or medullary hormones contributes to a number of well-known clinical syndromes.. They may result from benign or malignant adrenal tumours, adrenal hyperplasia or, least frequently, from extra-adrenal disease. Differentiation among these possibilities is often impossible on clinical or biochemical grounds alone. Location of the site(s) of excess hormone production in the past depended on relatively insensitive or invasive radiological methods. The non-invasive evaluation began with X-ray computed tomography but the functional significance of anatomical abnormalities cannot be determined from CT scan. Incorporation of specific radiopharmaceuticals into the abnormal tissues allows scintigraphic localization of functional abnormalities with a high degree of efficacy. The combination of adrenal scintigraphy and kompjuterizovanom tomografijom CT or magnetskom rezonancijom MRI should in most cases obviatc the need for more invasive procedures. Phaeochromocytoma is rare in hypertensive population, affecting only an estimated of 0.1%. However, a high index of suspicion is essential, since these tumours have potentially life-threatening cardiovascular effects and their successful resection is curative. Important clinical clues include the presence of orthostatic hypotension in an untreated hypertensive, resistance of hypertension to standard therapy (including possible exacerbation by (beta-blockers). In most cases, the diagnosis can be established by demonstrating high levels of free catecholamines and their metabolites (metanephrines and Vanillylmandelic acid). Clonidine test may be important in some cases. The purpose of this study is to point that metaiodobenzylguanidine (mlBG) has proved to be a safe, sensitive and highly specific agent for the location of phaeochromocytoma. The first successful schinigraphic demonstration of phaeochromocytomas in man was reported in 1981, using a new radiopharmaceutical, 131l

  6. Authentication of Medicines Using Nuclear Quadrupole Resonance Spectroscopy.

    Science.gov (United States)

    Chen, Cheng; Zhang, Fengchao; Barras, Jamie; Althoefer, Kaspar; Bhunia, Swarup; Mandal, Soumyajit

    2016-01-01

    The production and sale of counterfeit and substandard pharmaceutical products, such as essential medicines, is an important global public health problem. We describe a chemometric passport-based approach to improve the security of the pharmaceutical supply chain. Our method is based on applying nuclear quadrupole resonance (NQR) spectroscopy to authenticate the contents of medicine packets. NQR is a non-invasive, non-destructive, and quantitative radio frequency (RF) spectroscopic technique. It is sensitive to subtle features of the solid-state chemical environment and thus generates unique chemical fingerprints that are intrinsically difficult to replicate. We describe several advanced NQR techniques, including two-dimensional measurements, polarization enhancement, and spin density imaging, that further improve the security of our authentication approach. We also present experimental results that confirm the specificity and sensitivity of NQR and its ability to detect counterfeit medicines. PMID:26841409

  7. Childhood socioeconomic position, young adult intelligence and fillings of prescribed medicine for prevention of cardiovascular disease in middle-aged men

    DEFF Research Database (Denmark)

    Kriegbaum, Margit; Kildemoes, Helle Wallach; Rasmussen, Jeppe Nørgaard;

    2014-01-01

    To explore the relationship between childhood socioeconomic position (SEP) and filling of medicine prescriptions for prevention of cardiovascular diseases (CVDs), with young adult intelligence (IQ) as a potential mediator....

  8. Report on the second Congress of the Russian nuclear medicine society and on International conference Current problems of nuclear medicine and radiopharmaceuticals

    International Nuclear Information System (INIS)

    Information on the work of Second Congress of Russian Nuclear Medicine Society and International Conference - Current problems of nuclear medicine and radiopharmaceuticals, - held in Obninsk in October, 2000, is adduced. Reports presented in the conference are dedicated to various aspects of application of radionuclide methods to cardiology, angiology, oncology, surgery, hematology, endocrinology, pediatrics and neurology. Problems in the development of radiopharmaceutical, training and skill advancement of experts, dosimetry and radiation safety in nuclear medicine were discussed. Congress considered the organizational problems in Russian nuclear medicine

  9. American College of Nuclear Physics 1991 DOE day symposium: Aids and nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-12-31

    Since first described in 1981, the acquired immunodeficiency syndrome (AIDS) has become the medical dilemma of the century. AIDS retrovirus, and the economic consequences of this exposure are staggering. AIDS has been the topic of conferences and symposia worldwide. This symposium, to be held on January 25, 1991, at the 17th Annual Meeting and Scientific Sessions of the American College of Nuclear Physicians, will expose the Nuclear Medicine Physicians/Radiologists to their role in the diagnosis of AIDS, and will educate them on the socio-economic and ethical issues related to this problem. In addition, the Nuclear Medicine Physicians/Radiologists must be aware of their role in the management of their departments in order to adequately protect the health care professionals working in their laboratories. Strategies are currently being developed to control the spread of bloodborne diseases within the health care setting, and it is incumbent upon the Nuclear Medicine community to be aware of such strategies.

  10. Radiation doses to staff on a department of nuclear medicine

    International Nuclear Information System (INIS)

    A survey of data concerning radiation protection of staff working in the Nuclear Medicine Department and associated sections of the Physics Department at the Royal Marsden Hospital (Surrey Branch) is given for the period 1972 to 1975 inclusive. Results of routine film monitoring and whole-body counting are presented. Additional film monitors were used to check working areas, finger doses and any discrepancies between doses to the upper and lower trunk of personnel. In general, exposure to staff in the Nuclear Medicine Department is below 220 mrad per person per year, and below 1,000 mrad per person per year in the Radioisotope Dispensary. The dose received by radiographers is primarily due to spending time close to patients. Since about 5,000 intravenous injections of radionuclides are given each year in this department, the resulting finger doses to the staff involved may give rise to concern unless the task is shared. (author)

  11. Factor analysis of dynamic structures in nuclear medicine

    International Nuclear Information System (INIS)

    In the field of data processing in nuclear medicine, we applied the principal component analysis to the data acquired by the method of dynamic data acquisition. The radioisotope, taken in the body, shows inherent dynamic structures at the region of internal organ. We make some inherent patterns (Physiological Components) from T. A. C. (Time Activity Curve), and we represent dynamic structures of inherent patterns as functional image by the operation between inherent pattern and acquired data. This approach is called a Factor Analysis. In this paper, we introduce 1) The principle of factor analysis and its application to nuclear medicine, 2) the clinical application of factor analysis on SCINTIPAC-2400, and 3) the examinations and the comparison with other clinical application. (author)

  12. Establishment of dose reference levels for nuclear medicine in Greece.

    Science.gov (United States)

    Vogiatzi, S; Kipouros, P; Chobis, M

    2011-09-01

    Greek Atomic Energy Commission's Department of Licensing and Inspections conducted a national survey for the establishment of nuclear medicine (NM) dose reference levels (DRLs) for adult patients, in Greece. The administered activities (AAs) (MBq) were collected from 120 NM departments (88 % of total), during on-site inspections for licensing purposes. Factors influencing the image quality were also investigated. The established national DRLs represent the AA value corresponding to the 75th percentile of the AA frequency distributions. In their majority, national DRLs and average AAs are comparable with the ones published in the international literature. In the light of new technologies, there might be potential for reducing the higher values of AAs, in co-operation with the nuclear medicine experts. PMID:21765158

  13. Sensitometry in diagnostic radiology, radiation therapy, and nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Haus, A.G.; Rossmann, K.; Vyborny, C.; Hoffer, P.B.; Doi, K.

    The purpose of this paper is to present a tutorial discussion on the sensitometric methods employed for determining the characteristic curve of interest in diagnostic radiology, radiation therapy, and nuclear medicine. These methods are based on the way in which various recording systems are exposed in practice. In diagnostic radiology, an inverse-square sensitometer is used for measurements of the characteristic curves of conventional film and screen-film systems. In radiation therapy, a sensitometric technique can be used for the determination of the proper characteristic curve for a film which can be placed beneath the patient before radiation treatment and removed afterwards so that an image of the anatomy actually irradiated is obtained. In nuclear medicine, a sensitometric study served as a means of evaluating several radiographic films for imaging of the light output on an oscilloscope when the Anger camera is used.

  14. Search of new scintillation materials for nuclear medicine application

    CERN Document Server

    Korzhik, M V

    2000-01-01

    Oxide crystals have a great potential to develop new advanced scintillation materials which are dense, fast, and bright. This combination of parameters, when combined to affordable price, gives a prospect for materials to be applied in nuclear medicine devices. Some of them have been developed for the last two decades along the line of rear-earth (RE) garnet (RE/sub 3/Al/sub 5/O/sub 12/) oxiorthosilicate (RE/sub 2/SiO/sub 5/) and perovskite (REAlO/sub 3/) crystals doped with Ce ions. Among recently developed oxide materials the lead tungstate scintillator (PWO) becomes the most used scintillation material in high energy physics experiments due to its application in CMS and ALICE experiments at LHC. In this paper we discuss scintillation properties of some new heavy compounds doped with Ce as well as light yield improvement of PWO crystals to apply them in low energy physics and nuclear medicine. (18 refs).

  15. Contamination monitor as a nuclear stethoscope for community nuclear medicine

    International Nuclear Information System (INIS)

    A portable contamination monitor has been modified for use as an in vivo counting probe. The evaluation by physical parameters and clinical studies shows its suitability for a variety of diagnostic studies. The correlation equations for thyroid uptake measurement have been worked out for whole range of values. Its use as a versatile nuclear stethoscope is envisaged. (author)

  16. Nuclear medicine. 4. new rev. and enl. ed.

    International Nuclear Information System (INIS)

    The book on nuclear medicine is devided in three chapters: fundamentals, diagnostics and therapy. The topics within these chapters are the following: 1) fundamentals: molecular imaging; radiation physics, measuring technology and quality control; dosimetry and radiation effects; radiation protection, radiopharmaceutical chemistry; immonoassays and quality control. 2) diagnostics: endocrine organs; oncology; heart, vascular system and blood vessels; brain, lungs, skelton, kidneys, gastrointestine tract; infections; hematology. 3) radiotherapy; radiosynoviorothese; palliative bone pain therapy; radioimmunotherapy; 131I-MIBG therapy; therapy with receptor affine peptides; specific nuclear medical therapies

  17. Clinical nuclear medicine applications in Turkey and specific renal studies

    International Nuclear Information System (INIS)

    Nuclear cardiology, nuclear oncology, pediatric nuclear medicine and nuclear endocrinology are the main application areas of clinical nuclear medicine in Turkey. Not only imaging studies, but also therapeutic application of radiopharmaceuticals is also performed at many institutes, such as hyperthyroidism treatment with radioiodine, thyroid cancer ablation and metastases treatment with radioiodine, radio synovectomy, metastatic pain therapy, and recently radioimmunotherapy of lymphomas. Almost all radionuclides and radiopharmaceuticals are obtained commercially from European countries, except 18-FDG which is obtained from two cyclotrons in Turkey. More than 30.000 renal procedures are performed at the University hospitals in a year. Pediatric age groups is approximately % 55 of patients. 99mTc-DTPA (%44), 99mTc-DMSA (%37), 99mTc-MAG3 (%17) and 99mTc-EC (%2) are the most commonly used radiopharmaceuticals for renal imaging. More than 6.000 vials of several pharmaceuticals are used for renal cortical scintigraphy (%35), dynamic renal imaging (%34), renal scintigraphy with diuretic (%27) and captopril scintigraphy (%4). Most common indication for renal cortical scintigraphy is detection of cortical scarring (%53). In addition, using single plasma sample method or gamma-camera method renal clearance measurements with 99mTc-MAG3 99mTc-DTPA have been used at some institutions. (author)

  18. Clinical nuclear medicine applications in Turkey and specific renal studies

    International Nuclear Information System (INIS)

    Full text: Nuclear cardiology, nuclear oncology, pediatric nuclear medicine and nuclear endocrinology are the main application areas of clinical nuclear medicine in Turkey. Not only imaging studies, but also therapeutic application of radiopharmaceuticals is also performed at many institutes, such as hyperthyroidism treatment with radioiodine, thyroid cancer ablation and metastases treatment with radioiodine, radio synovectomy, metastatic pain therapy, and recently radioimmunotherapy of lymphomas. Almost all radionuclides and radiopharmaceuticals are obtained commercially from European countries, except 18-FDG which is obtained from two cyclotrons in Turkey. More than 30.000 renal procedures are performed at the University hospitals in a year. Pediatric age groups is approximately % 55 of patients. 99mTc-DTPA (%44), 99mTc-DMSA (%37), 99mTc-MAG3 (%17) and 99mTc-EC (%2) are the most commonly used radiopharmaceuticals for renal imaging. More than 6.000 vials of several pharmaceuticals are used for renal cortical scintigraphy (%35), dynamic renal imaging (%34), renal scintigraphy with diuretic (%27) and captopril scintigraphy (%4). Most common indication for renal cortical scintigraphy is detection of cortical scarring (%53). In addition, using single plasma sample method or gamma-camera method renal clearance measurements with 99mTc-MAG3 99mTc-DTPA have been used at some institutions

  19. Nuclear Medicine in Thyroid Diseases in Pediatric and Adolescent Patients

    OpenAIRE

    Bilge Volkan-Salancı; Pınar Özgen Kıratlı

    2015-01-01

    Both benign and malignant diseases of the thyroid are rare in the pediatric and adolescent population, except congenital hypothyroidism. Nuclear medicine plays a major role, both in the diagnosis and therapy of thyroid pathologies. Use of radioactivity in pediatric population is strictly controlled due to possible side effects such as secondary cancers; therefore, management of pediatric patients requires detailed literature knowledge. This article aims to overview current algorithms...

  20. Performance of dose calibrators used for nuclear medicine services

    International Nuclear Information System (INIS)

    This work show the results of the quality control tests from two different dose calibrators of a Nuclear Medicine Clinic in Sao Paulo. One of them has an ionization chamber (well type) and the other, Geiger-Mueller detectors (well configuration). As reference sources, Cobalt-57, Barium-133 and Caesium-137 were utilized. Also, an unsealed Technetium-99m source was used in some tests. Finally, the performance of both instruments was compared. (author)

  1. Nuclear medicine in dentistry revisited: New avenues to explore

    OpenAIRE

    Vinita Boloor; Rajesh Hosadurga; Sruthy Pratap; Anupama Rao

    2013-01-01

    Nuclear medicine and radioactive tracers have considerable application in dental research, because they provide one of the few practical methods for studying the limited metabolic activities of bones and teeth. The ease with which minute amounts of these radioactive materials may be accurately measured and distinguished from the mass of inert element in the tooth is particularly valuable. They are useful in studying many problems of calcification and mineral exchange. There are also opportuni...

  2. Radiation exposure in nuclear medicine: real-time measurement

    OpenAIRE

    Sylvain Iara; Bok Bernard

    2002-01-01

    French regulations have introduced the use of electronic dosimeters for personal monitoring of workers. In order to evaluate the exposure from diagnostic procedures to nuclear medicine staff, individual whole-body doses were measured daily with electronic (digital) personal dosimeters during 20 consecutive weeks and correlated with the work load of each day. Personal doses remained always below 20 µSv/d under normal working conditions. Radiation exposure levels were highest to tech staff, nur...

  3. Image interface in Java for tomographic reconstruction in nuclear medicine

    International Nuclear Information System (INIS)

    The aim of this study is to implement a software for tomographic reconstruction of SPECT data from Nuclear Medicine with a flexible interface design, cross-platform, written in Java. Validation tests were performed based on SPECT simulated data. The results showed that the implemented algorithms and filters agree with the theoretical context. We intend to extend the system by implementing additional tomographic reconstruction techniques and Java threads, in order to provide simultaneously image processing. (author)

  4. Ambient dose measurement and personal dosimetry in nuclear medicine

    International Nuclear Information System (INIS)

    The dose measurements reported were performed with TLD dosemeters consisting of two glass tubes filled with CaSO4:TM powder. The measurements were done around a positron emission tomograph, in a nuclear medicine outpatient department, and in a hospital (therapy with unsealed radioactive substances). The personal doses measured during the campaign reported did not exceed the range of radiation doses and its fluctuations due to natural radiation exposure of the population. (DG)

  5. The integral formation of the university technologists in nuclear medicine

    International Nuclear Information System (INIS)

    Full text: Nuclear medicine has contributed to notable benefits to the human health from the very beginning. The Radioisotopes techniques, as well as the ionizing radiation used, have evolved providing functional and anatomical information of the patient, through non-invasive methods. With reference to Radiological Protection, the justification of each one of these practices and its perfect execution is intimately related to the benefit provided to the patients. The National Atomic Energy Commission apart from favouring the scientific and technological development, considers indispensable to work thoroughly on the professional training of the prospective technologists. Our over twenty-year experience in organizing and delivering courses of Technologists in Nuclear Medicine, although based on a much simpler program, have allowed the Institute of Nuclear Studies of the Ezeiza Atomic Center to acquire the capacity of developing a program to train highly qualified Technologists in that field. This project represents a step forward of great importance to the graduates qualification, since they will have the endorsement of CNEA and of the Faculty of Medicine of the Maimonides University. These are the three outstanding characteristics agreed on: 1.- General Education, carried out by subjects closely related to the optimisation of the relation Technologist - Patient - Environment and represented by: Radiological Protection and Hospital Security, Psychology, Ethics and Professional Medical Ethics, Nursing, English, Hygiene and Hospital Security and Management of the Quality in Services of Health. 2.- Diagnostic Procedures: planned according to organs, apparatuses or systems which are horizontally crossed by the anatomy, physiology and physiopathology Preparation of the patient, indications, main counter indications, radiopharmaceuticals, mechanisms of incorporation, pathologies, clinical protocols, instrumentation, post radiopharmaceuticals administration imaging

  6. Nuclear Medicine: Use of Thallium 201 in Tumor Evaluation

    OpenAIRE

    Waxman, Alan D.

    1992-01-01

    The Council on Scientific Affairs of the California Medical Association presents the following inventory of items of progress in nuclear medicine. Each item, in the judgment of a panel of knowledgeable physicians, has recently become reasonably firmly established, both as to scientific fact and important clinical significance. The items are presented in simple epitome, and an authoritative reference, both to the item itself and to the subject as a whole, is generally given for those who may b...

  7. Some current aspects of the staff protection in nuclear medicine

    International Nuclear Information System (INIS)

    The paper discusses some specific questions of irradiation of workers in various professions on typical nuclear medicine workplace in connection with the performance of their specific tasks. There are also given the results of the monitoring of individual doses, which show the significant differences in exposure of personnel groups. Special attention is paid to the protection of workers and others who come into contact with patients who received high-level radiopharmaceuticals for therapeutic purposes. (authors)

  8. Forensic Medicine: Age Written in Teeth by Nuclear Bomb Tests

    Energy Technology Data Exchange (ETDEWEB)

    Lawrence Livermore National Laboratory

    2005-05-04

    Establishing the age of individuals is an important step in identification and a frequent challenge in forensic medicine. This can be done with high precision up to adolescence by analysis of dentition, but establishing the age of adults has remained difficult. Here we show that measuring {sup 14}C from nuclear bomb tests in tooth enamel provides a sensitive way to establish when a person was born.

  9. TLD occupational dose distribution study in nuclear medicine

    International Nuclear Information System (INIS)

    The large and growing number of patients undergoing nuclear medicine procedures and workers involved in this practice requires continued efforts to improve the quality of diagnosis and to reduce the radiological risk associated. In Brazil, external individual monitoring with a dosemeter located on the thorax is compulsory for all workers in controlled areas. Extremity dosemeters are recommended in activities where hand dose can be much higher than on the thorax. This is typically the case for nuclear medicine procedures, but extremity dosemeters are not regularly used in Brazil. With the aim to study the occupational dose distribution in the nuclear medicine staff during their tasks of preparation and injection of radionuclides, Harshaw TLD chips of LiF:Mg,Cu,P (TLD-100H) were used for individual monitoring on different parts of the worker body. As expected, all doses measured on the thorax were much lower than on the hands. For both Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET), the dose to the fingers during preparation is about two orders of magnitude higher than in the thorax, and in the injection procedure, one order higher. The doses received by the workers' fingers varied widely depending on how they hold the syringe, but fingertips always received higher doses. The dose values measured in the eye lens were 200% higher than the one measured on the thorax. - Highlights: • The highest doses in nuclear medicine procedures occur at the fingertips. • Dosimetric bracelet may underestimate the dose at the hands by up to a factor of 25. • Eye lens dose equivalent dose can be twice the Hp(10) value measured on the thorax. • Adequate shielding, tools and training are important parameters for dose reduction

  10. New aspects regarding to radiation protection in nuclear medicine

    International Nuclear Information System (INIS)

    Introduction and objectives: The society has been concerned about nuclear energy usage and nuclear environment pollution for ages. The necessity of using radiation and its applications in modern life especially in medicine is undeniable. Some interesting properties such as the potential for non-destructive tests, detection simplicity, and penetrability into substances and having reactions with them cause radiation to be known as a useful tool for peace purposes. Nuclear weapons' experiments (1945-1973) and nuclear accidents in Three-Mile Island in USA, Goiania in Brazil and Chernobyl in Ukraine Republic have enhanced man's worries towards nuclear radiation and radioactivity in environment, and founding associations and groups which are against nuclear energy, such as green peace society, can be related with above mentioned concerns. Today, nuclear medicine has rapidly been developed so that in some cases plays a unique role in diagnosis but unfortunately in spite of diagnostic and therapeutic advantages, the term NUCLEARcan induce worries in patients and society. In this article, base on new documents we intend to show that this worries has no scientific basis. Material and Methods: To produce a realistic view, regarding to radiation protection we used several ways such as natural origin of radiation, high natural background radiation areas' data non-linear dose-effect model, risk versus benefit, use of arbitrary unit for measurement of radiation, radio adaptive response and radiation hormesis. Discussion and conclusion: Harmful effects of radiation on biologic systems has obviously been shown, but most of related documents are based on receiving high doses in nuclear and atomic accidents and explosions and radiation protection regulations are based on this observations. So, it sometimes causes patients are afraid of low doses of radiation in medical diagnostic procedures so that some of them even resist against performing this procedures. Thus, being aware of

  11. Assessment of OEP health's risk in nuclear medicine

    Science.gov (United States)

    Santacruz-Gomez, K.; Manzano, C.; Melendrez, R.; Castaneda, B.; Barboza-Flores, M.; Pedroza-Montero, M.

    2012-10-01

    The use of ionizing radiation has been increased in recent years within medical applications. Nuclear Medicine Department offers both treatment and diagnosis of diseases using radioisotopes to controlled doses. Despite the great benefits to the patient, there is an inherent risk to workers which remains in contact with radiation sources for long periods. These personnel must be monitored to avoid deterministic effects. In this work, we retrospectively evaluated occupationally exposed personnel (OEP) to ionizing radiation in nuclear medicine during the last five years. We assessed both area and personal dosimetry of this department in a known Clinic in Sonora. Our results show an annual equivalent dose average of 4.49 ± 0.70 mSv in OEP without showing alarming changes in clinical parameters analyzed. These results allow us to conclude that health of OEP in nuclear medicine of this clinic has not been at risk during the evaluated period. However, we may suggest the use of individual profiles based on specific radiosensitivity markers.

  12. What does the gastro-enterologist expect from nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Claasen, M.

    1987-04-01

    The close cooperation between the specialists in nuclear medicine and gastroenterology is illustrated by several examples: The rate of bleeding sources within the small intestine, as detected by endoscopy, X-ray contrast studies of the (intestinal) lumen, and angiography, is not sufficiently high, but has been reported to be in a range of 50-100 per cent if labelled autologous erythrocytes are used, provided a bleeding rate of 1 ml/min. at least. Inflammatory areas in cases of Morbus Crohn (skip lesions) are of importance for the evaluation of functional impairments and thus for therapy. Modern studies using labelled granulocytes show a good correlation to endoscopic and histologic findings, both with regard to their spatial distribution and activity. Additional comparisons to the 'gold standard' endoscopy would be desirable. Treatment with monoclonal antibodies, which would act as a radiant 'destroyer' to exclusively destroy the tumour cells, could provide an important approach to therapy of inoperable tumours of the digestive tract. Nuclear medicine also is expected to provide valuable contributions to investigations of the bacterial flora of the small intestine and to coagulation studies in cases of liver failure. AT III-labelling has enabled the intrahepatic AT III-consumption to be detected in cases of liver failure. The gastro-enterologist expects nuclear medicine to cooperate in the solution of clinical and research problems of digestive diseases.

  13. Radionuclide calibrator comparisons and quality improvement in nuclear medicine.

    Science.gov (United States)

    Oropesa, P; Woods, M J; Olsovcová, V; dos Santos, J A

    2008-03-01

    The traceability of activity measurements performed during the development phase of the radiopharmaceutical and in its clinical application is essential for establishing the comparability of clinical results reported in the nuclear medicine field. This paper presents and discusses the evaluation over time of the quality of activity measurement results obtained in Cuban nuclear medicine, on the basis of statistical samples taken during the radionuclide calibrator comparison program. An attempt is also made to evaluate the role played by such comparisons in quality measurement improvement in nuclear medicine, on the basis of results obtained in a number of countries and published by several authors over a period of time. Specifically, improvements of the measurement performance over time assessed by such exercises were found dissimilar in magnitudes for different countries. Two phases could be distinguished in the improvement process over time. Firstly, a fast improvement can be obtained resulting from the improvement in measurement accuracy of devices. After that, the achievement of new and sustained improvements goes slowly and requires an application of quality assurance programs where the qualification upgrading of personnel become an essential point. PMID:17855099

  14. Digital nuclear medicine department: Is a filmless environment conceivable?

    International Nuclear Information System (INIS)

    Recent hardware improvements, the installation and development of fast networks and new technologies for storage of large data volumes all contribute to the propagation of digital reading and reporting of nuclear medicine studies. Thus, the vision of a fully digitized nuclear medicine department becomes reality. The high costs of purchasing hardware- and software-components are compensated by saving costs of films and by the improvement of the work flow in the long run. Independently from these issues, filmless reporting proves to be advantageous over conventional film reading in many facts that justify to switch to a digital department. Problems that occur in the process of becoming film-free are mainly based on compatibility issues and demand strong cooperation between the user and the manufacturer of the imaging devices in order to integrate all systems into one reading and reporting tool. The departments of nuclear medicine and radiology of the University of Munich, Innenstadt, now are reviewing a one-year process of being film-free, which makes a return to conventional film reading unconceivable. (orig.)

  15. Organization and regulation of nuclear medicine and radiotherapy in Argentina

    International Nuclear Information System (INIS)

    After describing the efforts carried out in Argentina during the decade of 1970 to consolidate nuclear medicine as a new clinical specialty, reference is made to the constitution, in 1979, of a Joint Advisory Committee on Nuclear Medicine and Radiotherapy integrated by members of the National Atomic Energy Commission and by members of the Public Health Ministry of the Nation, with the purpose to coordinate and plan said activities within the country. Two recommendations of said Advisory Committee are transcribed. The first one defines the different specialties of the professionals and technicians working in the new discipline. The second recommendation is referred to the regulations on ''Operation of Nuclear Medicine Units'', which set up different categories of medical establishments of the specialty (''unit'', ''service'' and ''center''), define their respective functions as well as the equipment and specialized personnel that they should be fitted with in each case, and institute the requirement to demonstrate having the corresponding academic and professional up-dating in the specialty to obtain the periodic revalidation of operation licences. (C.A.K.)

  16. Medicine and ionizing rays: a help sheet in analysing risks in nuclear medicine

    International Nuclear Information System (INIS)

    This document first proposes the various applicable legal and regulatory texts concerning radioprotection in the medical sector (European directives, institutions in charge of radioprotection, general arrangements, regulatory texts concerning worker protection against ionizing radiations, personnel specialized in medical radio-physics, electro-radiology operators, quality control of medical devices, and nuclear medicine and radiology). The second part proposes a synthesis of useful knowledge for radioprotection in the case of nuclear medicine when performing in vivo diagnosis, positron emission tomography or PET being excluded. Several aspects are considered: the concerned personnel, the course of treatment procedures, the hazards, the identification of the risk associated with ionizing radiation, the risk assessment and the determination of exposure levels, the strategy to control the risks (reduction of risks, technical measures concerning the installation or the personnel, teaching and information, prevention and medical monitoring), and risk control assessment. The next parts present the same kind of information but for positron emission tomography or PET with Fluorine 18, for therapeutic practice without hospitalization (activity of iodine 137 less than 740 MBq), for therapeutic practice in case of hospitalization (iodine 137 activity greater than 740 MBq), and when taking patients into care after treatment in a nuclear medicine (in this last case, legal and regulatory information focus on patients)

  17. Recommendations in health protection and fitness for work for nuclear medicine specialists

    OpenAIRE

    Seyedeh Negar Assadi

    2010-01-01

    Introduction: Nuclear medicine is one of the most helpful and beneficial specialties for diagnosis and treatment of diseases and health protections are the most important subject in occupational medicine, Specially in exposure to ionizing radiation of radioactive materials are demonstrated for nuclear medicine specialists .Objective is determination of recommendations in health protection and fitness for work for nuclear medicine specialists and their nurses. Methods: This is a revie...

  18. Highlights of the 25th Anniversary EANM Congress Milan 2012: nuclear medicine and molecular imaging at its best.

    Science.gov (United States)

    Langsteger, Werner; Beheshti, Mohsen

    2013-09-01

    The European Association of Nuclear Medicine (EANM) celebrated its 25th Anniversary Congress in Milan under the chairmanship of Professor Emilio Bombardieri and the auspices of the Italian Society of Nuclear Medicine. As always, the Congress was a great success: more than 5,530 participants from 88 countries came from Europe and beyond. In spite of limited budgets, industry again made an important contribution: New innovative equipment and tracers demonstrating the latest technology and innovations were presented by 122 companies. This review is a brief summary of the major scientific contributions made in the fields of oncology, multimodality imaging, cardiovascular science, neurology and psychiatry, technological innovation and novel tracers, and in other clinical sciences as well as in radionuclide therapy, which all show promising and great innovations. PMID:23917722

  19. Availability, price and affordability of cardiovascular medicines: A comparison across 36 countries using WHO/HAI data

    Directory of Open Access Journals (Sweden)

    Cameron Alexandra

    2010-06-01

    Full Text Available Abstract Background The global burden of cardiovascular disease (CVD continues to rise. Successful treatment of CVD requires adequate pharmaceutical management. The aim was to examine the availability, pricing and affordability of cardiovascular medicines in developing countries using the standardized data collected according to the World Health Organization/Health Action International methodology. Methods The following medicines were included: atenolol, captopril, hydrochlorothiazide, losartan and nifedipine. Data from 36 countries were analyzed. Outcome measures were percentage availability, price ratios to international reference prices and number of day's wages needed by the lowest-paid unskilled government worker to purchase one month of chronic treatment. Patient prices were adjusted for inflation and purchasing power, procurement prices only for inflation. Data were analyzed for both generic and originator brand products and the public and private sector and summarized by World Bank Income Groups. Results For all measures, there was great variability across surveys. The overall availability of cardiovascular medicines was poor (mean 26.3% in public sector, 57.3% private sector. Procurement prices were very competitive in some countries, whereas others consistently paid high prices. Patient prices were generally substantially higher than international references prices; some countries, however, performed well. Chronic treatment with anti-hypertensive medication cost more than one day's wages in many cases. In particular when monotherapy is insufficient, treatment became unaffordable. Conclusions The results of this study emphasize the need of focusing attention and financing on making chronic disease medicines accessible, in particular in the public sector. Several policy options are suggested to reach this goal.

  20. Medical application of nuclear science: nuclear medicine and production of radiopharmaceuticals

    International Nuclear Information System (INIS)

    Nuclear science in attendance on medicine or from Radium to Radiopharmaceuticals. By a brief historical reminder of the evolution of the radioactivity and development of nuclear science, we could see a very early interest and application of the radioactivity in the medical field. Main steps: Detection of natural radioactivity/Discovery of artificial radioactivity/First treatment of leukaemia and thyroid/First nuclear reactor/First radioisotope laboratory in hospital/First scintigraphy/First radiopharmaceutical/First cyclotron and cyclotron products/First immunoscintigraphy/Biotechnology and radioisotope/Evolution of technics [equipment for diagnosis (imaging, scintigraphy) and therapy]/Evolution of production technics and concept of products (generators of Technetium) and machines, reactor, cyclotron/Evolution of importance and interest of nuclear medicine/Creation of international association of nuclear medicine and producers (example ARPR)/Evolution of safety and pharmaceuticals regulation. After the sixties, period extremely rich in invention of products, characterized by a high fertility specially due to a non-restrictive regulation in terms of safety and pharmaceutical consideration, the evolution of technics, the importance of costs (investment, research, healthcare and the evolution of the regulations) have smoothly but continuously transformed the contexts and different actors. Consequences and facts: Rationalization and standardization of the catalogues, total integration of radiopharmaceuticals into the pharmaceutical laws, stop of nuclear research reactors, increase of number of cyclotrons, transformation of size and role of the producers and nuclear centers, risk in supply of some raw materials like Molybdenum, medical nuclear application as a worldwide business

  1. The role of commercial nuclear pharmacy in the future practice of nuclear medicine.

    Science.gov (United States)

    Callahan, R J

    1996-04-01

    It has been estimated that today 70% to 80% of all radiopharmaceutical doses are dispensed through commercial nuclear pharmacy channels. These services are provided by the approximately 250 facilities in the United States, with some multisite corporations dispensing in excess of 20,000 unit-dose prescriptions per day. As pressures mount within health care institutions to reduce manpower, increase cost-effectiveness, increase participation in managed care contracts, and to seek outside vendors for many services that were previously provided in-house, the future role of the commercial nuclear pharmacy in the practice of nuclear medicine will only continue to increase. The essence of nuclear pharmacy practice is the dispensing of a full range of high quality radiopharmaceuticals in patient-specific unit doses. These doses must be delivered in a timely and cost effective manner, without compromising quality or patient safety. Commercial nuclear pharmacies have expanded to provide such varied functions as radiation safety and waste management, as well as consultative and marketing activities directed towards clinicians within a nuclear medicine practitioners own facility. In-service continuing education programs directed towards physicians and technologists are frequently offered by many commercial nuclear pharmacies. Changes in health care economics, merging and down-sizing in the hospital industry, and the overall impact of managed care on the viability of hospitals in general has resulted in slow growth, or even a small decline in the number of institutionally based nuclear pharmacists. As a result, nuclear medicine practitioners will be looking to the commercial nuclear pharmacies to meet a larger portion of their radiopharmaceutical needs, as well as to value added services, such as education and research and development. Specialized practice settings, such as nuclear cardiology and free-standing nuclear medicine clinics, are especially well suited to the services

  2. Assessment of radiation dose in nuclear cardiovascular imaging using realistic computational models

    NARCIS (Netherlands)

    Xie, Tianwu; Lee, Choonsik; Bolch, Wesley E.; Zaidi, Habib

    2015-01-01

    Purpose: Nuclear cardiology plays an important role in clinical assessment and has enormous impact on the management of a variety of cardiovascular diseases. Pediatric patients at different age groups are exposed to a spectrum of radiation dose levels and associated cancer risks different from those

  3. Nuclear medicine in Uzbekistan: Past, present and future

    International Nuclear Information System (INIS)

    Full text: Uzbekistan is one of the biggest countries in Middle Asia with a population of about 26.5 million. Nuclear Medicine in Uzbekistan has a long history. The first Nuclear Medicine Departments were organized in the 1950s and spread quickly in the 1960's when the number grew to 22 nuclear medicine centres in whole country. They were equipped with probe renogram, scanners, multiprobes and anger gamma cameras. As far as the Nuclear Medicine Department of Republic Specialized Center of Surgery is concerned, it was organized in 1976 and the first equipment of the institution was the anger gamma camera, ''Nuclear Chicago,'' as well as the probe renogram and multiple probes. At that time, the spectre of Nuclear Medicine examinations included: renoscintigraphy with I-131 hippuran, thyroid scintigraphy with I-131, MUGA, hepatic scintigraphy with sulphur colloid and HIDA, lung perfusion and ventilation, lymphoscintigraphy of low extremities, radiography (investigation of central hemodynamic), dynamic brain perfusion, bone scintigraphy of bone transplant, selective radionuclide angiography (examination of peripheral microcirculation) and phleboscintigraphy of low extremities. Unfortunately, the situation changed during the first years of Uzbekistan independence (1991) due to the economic situation. The number of Nuclear Medicine Departments decreased to 10. However, the NM Department of Republic Specialised Center of Surgery never stopped its clinical and research work. Nonetheless, the number of examinations performed significantly dropped. A new era of Nuclear Medicine in Uzbekistan was started in 2000 when the IAEA approved the TC project ''Introduction of SPECT in Uzbekistan''. With the great help of IAEA, the Republic Specialised Center of Surgery received a single head SPECT gamma camera (E-CAM Siemens). Furthermore, under the next TC project ''Implementation of NM in Uzbekistan,'' the same Center received a second SPECT dual head gamma camera (Nucline Spirit

  4. Some Applications of Nuclear Physics in Medicine and Dentistry

    International Nuclear Information System (INIS)

    Some applications of nuclear physics, to solve problems in dentistry and medicine are presented. The following two topics are going to be discussed: A. Nuclear Analytical Methods For Trace Element Studies In Teeth Various nuclear analytical methods have been developed and applied to determine the elemental composition of teeth. Fluorine was determined by prompt gamma activation analysis through the 19F (p, a v)16O reaction. Carbon was measured by activation analysis with He-3 ions, and the technique of Proton-Induced X-ray Emission (PIXE) was applied to simultaneously determine Ca, P, and trace elements in well-documented teeth. Dental hard tissues: enamel, dentine, cement, and their junctions, as well as different parts of the same tissue, were examined separately.

  5. Training and education in nuclear medicine at the Medical Faculty of the University of Zagreb

    International Nuclear Information System (INIS)

    Training for specialization in nuclear medicine in Yugoslavia includes 12 months of training in departments of clinical medicine and 24 months of training in departments of nuclear medicine. Since 1974 many physicians have passed the specialist examination in Zagreb. A postgraduate study in nuclear medicine began at the Medical Faculty of the University of Zagreb in 1979. It includes four semesters of courses and research on a selected subject leading to the degree of Magister (Master of Science). Most of the training is conducted by the Institute of Nuclear Medicine at the University Hospital, Rebro, in Zagreb, which has the necessary teaching staff, equipment and space. Forty-four students have completed this postgraduate study. Nuclear medicine in a developing country faces several problems. Scarcity of expensive equipment and radiopharmaceuticals calls for modifications of methods, home made products and instrument maintenance. These, mostly economic, factors are given special emphasis during training. Nuclear power generation may solve some of the country's energy problems; therefore, specialists in nuclear medicine must obtain additional knowledge about the medical care and treatment of persons who might be subject to irradiation and contamination in nuclear power plants. Lower economic resources in developing countries require better trained personnel, stressing the need for organized training and education in nuclear medicine. With some support the Institute of Nuclear Medicine will be able to offer various forms of training and education in nuclear medicine for physicians, chemists, physicists, technologists and other personnel from developing countries. (author)

  6. The contribution of physics to Nuclear Medicine: physicians’ perspective on future directions

    OpenAIRE

    Mankoff, David A.; Pryma, Daniel A.

    2014-01-01

    Background Advances in Nuclear Medicine physics enabled the specialty of Nuclear Medicine and directed research in other aspects of radiotracer imaging, ultimately leading to Nuclear Medicine’s emergence as an important component of current medical practice. Discussion Nuclear Medicine’s unique ability to characterize in vivo biology without perturbing it will assure its ongoing role in a practice of medicine increasingly driven by molecular biology. However, in the future, it is likely that ...

  7. Powder ink coatings in nuclear medicine and nuclear technology

    International Nuclear Information System (INIS)

    Powder ink coatings are being used more and more frequently to protect the surfaces of movable objects of metal, such as machines, equipment, furniture, shelves, because this solvent-free coating technique, which produces almost no residues, helps to keep the environment clean. The white and grey baking coatings so far tested for decontaminability are presented in the article. Powder ink coatings of different shades and with different binders were tested for their ability to meet future standards. All systems under examination demonstrated excellent decontaminability before and after gamma exposure to 0.3 MGy. The same performance was obtained also after exposure to 3 MGy (ten times the level required for coatings in nuclear installations according to DIN 55991 Part 1), with the exception of one polyester metallic coating. After having been exposed to chemicals and decontamination solutions, all specimens showed only permissible discoloration. (orig.)

  8. Results of a national survey on nuclear medicine procedures

    International Nuclear Information System (INIS)

    Full text: In 1997, the Nuclear Regulatory Authority of Argentina carried out a compilation of data on radiopharmaceuticals administered to patients in nuclear medicine procedures. Its aim was to get information on the radiopharmaceuticals that are used in different procedures and the activity administered to the patient, to assess the radiation exposure of the population and to contribute to a global survey of medical radiation usage and exposures conducted by the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR), by sending information of the country. The data compiled were analysed, and for the most frequent procedures, the mean activity administered, the standard deviation, the distribution of the number of procedures for different age groups, sex and radiopharmaceuticals were assessed. The radiation exposure for children and adults was estimated. For the main diagnostic examinations, the results of the survey were compared with specific values published in the Basic Safety Standards of the International Atomic Energy Agency (Safety Series No. 115, 1996). As a conclusion, it may be point out the importance of continuing with the compilation of this kind of information in order to identify emerging trends on the use of nuclear medicine procedures in Argentina and the activity of radiopharmaceuticals administered to the patients. (author)

  9. Chinese herbal medicine and acupuncture for the treatment of cardiovascular disease

    Institute of Scientific and Technical Information of China (English)

    Jun Xu; Haiyun Wu

    2009-01-01

    @@ Traditional Chinese medicine (TCM) is one of the world's oldest healing systems. TCM includes herbal medicine, acupuncture, moxibustion, massage, food therapy, and physical exercise, such as shadow boxing. In modern China, TCM is a fully institutionalised part of health care and widely used with Western medicine.

  10. Tetrandrine and related bis-benzylisoquinoline alkaloids from medicinal herbs: cardiovascular effects and mechanisms of action

    Institute of Scientific and Technical Information of China (English)

    Chiu-Yin KWAN; FI ACHIKE

    2002-01-01

    Tetrandrine (TET), a bis-benzylisoquinoline alkaloid purified and identified an active ingredient in a Chinese medicinal herb, Radix Stephanae tetrandrae, has been used traditionally for the treatment of congestive circulatory disorder and inflammatory diseases. TET, together with a few of its structural analogues, has long been demonstrated to have antihypertensive action in clinical as well as animal studies. Presumably, the primary anti-hypertensive action of TET is due to its vasodilatory properties. TET prevents or inhibits vascular contraction induced by membrane depolarization with KCl or α-adrenoceptor activation with phenylephrine (PE). TET (30 μmol/L) also inhibits the release of endothelium-derived nitric oxide (NO) as well as NO production by inducible NO synthase.TET apparently inhibits multiple Ca2+ entry pathways as demonstrated in cell types lacking the L-type Ca2+ channels.In cardiac muscle cells, TET inhibits both L- and T-type Ca2+ channels. In addition to its actions on cardiovascular tissues, TET may also exert its anti-hypertensive action via a Ca2+-dependent manner on other tissues intimately involved in the modulation of blood pressure control, such as adrenal glands. In adrenal glomerulosa cells, KCl- or angiotensin II-induced aldosterone synthesis is highly dependent on extracellular Ca2+. Steroidogenesis and Ca2+-influx in bovine adrenal glomerulosa cells have been shown to be potently inhibited by TET. In bovine adrenal chromaffin cells, TET inhibits Ca2+ currents via L- and N-type channels as well as other unidentified channels with IC50 of 10 μmol/L. Other than the Ca2+ antagonistic effects, TET also interacts with the α-adrenergic receptors and muscarinic receptors based on functional as well as radioligand binding studies. Apart from its functional effects,TET and related compounds also exert effects on tissue structures, such as remodelling of hypertrophied heart and inhibition of angiogenesis, probably by causing apoptotic

  11. XIX Congress of the Latin-American Association of Societies of Nuclear Medicine and Biology (ALASBIMN), Cancun, Mexico, May, 2003

    International Nuclear Information System (INIS)

    From May 25 to 30, 2003 the beautiful city of Cancun, located in the heart of the ancient Maya Empire in Mexico, hosted the XIX ALASBIMN CONGRESS. More than 300 attendees and 80 lecturers from the American continent and Europe had the opportunity to share their knowledge and enjoy an outstanding scientific, cultural and social program. The Scientific program included reviews and original scientific papers on basic and clinical sciences as well as on new developments in diagnostic and therapeutic nuclear medicine. Cardio-vascular, neuropsychiatric, oncology, skeletal and paediatric procedures were comprehensively analysed by several experts. Introduction of new cyclotrons and modern PET and PET/CT systems in Latin America has opened new horizons for the nuclear medicine community in this sub-continent. New radiopharmaceuticals based on different peptides, receptors and gene expression dominated the scene. Reporter gene imaging of gene expression has become the first and best example of what is achievable by modern molecular imaging. Of particular interest was the presentation of novel and potential agents for radio-metabolic therapy. Additionally, in connection with the congress the IAEA organised a very successful Regional Training Course on Paediatric Nuclear Medicine with 23 participants from 11 countries. The Agency also hosted the first national project coordinators meeting of the IAEA Regional Project aimed at establishing a regional tele-nuclear medicine network in the Latin American Region in conjunction with the ALASBIMN meeting. Once again the major companies representing the nuclear medicine industry participated in the Congress and contributed to the success of the ALASBIMN meeting. In summary, attending the XIX ALASBIMN meeting was a very rewarding experience in every aspect. We are most grateful to the organisers for hosting such a nice congress. Congratulations! Now we are looking forward to participate in the next ALASBIMN Congress to be held in the

  12. Monte Carlo techniques in diagnostic and therapeutic nuclear medicine

    International Nuclear Information System (INIS)

    Monte Carlo techniques have become one of the most popular tools in different areas of medical radiation physics following the development and subsequent implementation of powerful computing systems for clinical use. In particular, they have been extensively applied to simulate processes involving random behaviour and to quantify physical parameters that are difficult or even impossible to calculate analytically or to determine by experimental measurements. The use of the Monte Carlo method to simulate radiation transport turned out to be the most accurate means of predicting absorbed dose distributions and other quantities of interest in the radiation treatment of cancer patients using either external or radionuclide radiotherapy. The same trend has occurred for the estimation of the absorbed dose in diagnostic procedures using radionuclides. There is broad consensus in accepting that the earliest Monte Carlo calculations in medical radiation physics were made in the area of nuclear medicine, where the technique was used for dosimetry modelling and computations. Formalism and data based on Monte Carlo calculations, developed by the Medical Internal Radiation Dose (MIRD) committee of the Society of Nuclear Medicine, were published in a series of supplements to the Journal of Nuclear Medicine, the first one being released in 1968. Some of these pamphlets made extensive use of Monte Carlo calculations to derive specific absorbed fractions for electron and photon sources uniformly distributed in organs of mathematical phantoms. Interest in Monte Carlo-based dose calculations with β-emitters has been revived with the application of radiolabelled monoclonal antibodies to radioimmunotherapy. As a consequence of this generalized use, many questions are being raised primarily about the need and potential of Monte Carlo techniques, but also about how accurate it really is, what would it take to apply it clinically and make it available widely to the medical physics

  13. Characterization of iodinated adrenomedullin derivatives suitable for lung nuclear medicine

    Energy Technology Data Exchange (ETDEWEB)

    Fu Yan; Letourneau, Myriam; Chatenet, David [Laboratoire d' etudes moleculaires et pharmacologiques des peptides, INRS-Institut Armand-Frappier, Ville de Laval, Qc, H7V 1B7 (Canada); Dupuis, Jocelyn [Research Center, Montreal Heart Institute, Montreal, Qc (Canada); Department of Medicine, University of Montreal, Montreal, Qc (Canada); Fournier, Alain, E-mail: alain.fournier@iaf.inrs.ca [Laboratoire d' etudes moleculaires et pharmacologiques des peptides, INRS-Institut Armand-Frappier, Ville de Laval, Qc, H7V 1B7 (Canada)

    2011-08-15

    Introduction: We have recently demonstrated the effectiveness of 99m-technetium adrenomedullin (AM) as a new molecular lung imaging agent that could provide significant advantages for the diagnosis and follow-up of disorders affecting the pulmonary circulation such as pulmonary embolism and pulmonary hypertension. Having the possibility to conjugate the targeting molecule with different radionuclides would offer more flexibility and potential advantages depending on clinical situations. Since various iodine isotopes are currently used in nuclear medicine and in pharmacological studies, we have evaluated which iodination method should be privileged in order to produce a good iodinated AM-derived nuclear medicine agent. Methods: Synthetic AM was labeled with iodine through chemical and lactoperoxidase oxidation methods. Position of the iodine atom on the peptide was determined by MALDI-TOF mass spectrometry analysis following cyanogen bromide cleavage and carboxypeptidase Y digestion. Binding affinity of iodinated AM analogues was evaluated by competition and saturation binding experiments on dog lung preparations. Results: In this study, we demonstrated that, upon lactoperoxidase oxidation, iodination occurred at Tyr{sup 1} and that this radioligand retained higher binding affinity and specificity over preparations obtained through chemical oxidation. Conclusions: These results emphasize the fact that even a small chemical modification, i.e. iodination, might deeply modify the pharmacological profile of a compound and support observations that the C-terminal tail of human AM plays an important role in the AM receptor binding process. Consequently, incorporation of a radionuclide to produce an AM-based nuclear medicine agent should privilege the N-terminus of the molecule.

  14. Absorbed Doses to Patients in Nuclear Medicine; Doskatalogen foer nukleaermedicin

    Energy Technology Data Exchange (ETDEWEB)

    Leide-Svegborn, Sigrid; Mattsson, Soeren; Nosslin, Bertil [Universitetssjukhuset MAS, Malmoe (Sweden). Avd. foer radiofysik; Johansson, Lennart [Norrlands Universitetssjukhus, Umeaa (Sweden). Avd. foer radiofysik

    2004-09-01

    The work with a Swedish catalogue of radiation absorbed doses to patients undergoing nuclear medicine investigations has continued. After the previous report in 1999, biokinetic data and dose estimates (mean absorbed dose to various organs and tissues and effective dose) have been produced for a number of substances: {sup 11}C- acetate, {sup 11}C- methionine, {sup 18}F-DOPA, whole antibody labelled with either {sup 99m}Tc, {sup 111}In, {sup 123}I or {sup 131}I, fragment of antibody, F(ab'){sub 2} labelled with either {sup 99m}Tc, {sup 111}In, {sup 123}I or {sup 131}I and fragment of antibody, Fab' labelled with either {sup 99m}Tc, {sup 111}In, {sup 123}I or {sup 131}I. The absorbed dose estimates for these substances have been made from published biokinetic information. For other substances of interest, e.g. {sup 14}C-urea (children age 3-6 years), {sup 14}C-glycocholic acid, {sup 14}C-xylose and {sup 14}C-triolein, sufficient literature data have not been available. Therefore, a large number of measurements on patients and volunteers have been carried out, in order to determine the biokinetics and dosimetry for these substances. Samples of breast milk from 50 mothers, who had been subject to nuclear medicine investigations, have been collected at various times after administration of the radiopharmaceutical to the mother. The activity concentration in the breast milk samples has been measured. The absorbed dose to various organs and tissues and the effective dose to the child who ingests the milk have been determined for 17 different radiopharmaceuticals. Based on these results revised recommendations for interruption of breast-feeding after nuclear medicine investigations are suggested.

  15. Clinical Training of Medical Physicists Specializing in Nuclear Medicine

    International Nuclear Information System (INIS)

    The application of radiation in human health, for both diagnosis and treatment of disease, is an important component of the work of the IAEA. The responsibility for the increasingly technical aspects of this work is undertaken by the medical physicist. To ensure good practice in this vital area, structured clinical training programmes are required to complement academic learning. This publication is intended to be a guide to the practical implementation of such a programme for nuclear medicine. There is a general and growing awareness that radiation medicine is increasingly dependent on well trained medical physicists who are based in a clinical setting. However an analysis of the availability of medical physicists indicates a large shortfall of qualified and capable professionals. This is particularly evident in developing countries. While strategies to increase educational opportunities are critical to such countries, the need for guidance on structured clinical training was recognized by the members of the Regional Cooperative Agreement for Research, Development and Training related to Nuclear Science and Technology (RCA) for the Asia-Pacific region. Consequently, a technical cooperation regional project (RAS6038) under the RCA programme was formulated to address this need in this region by developing suitable material and establishing its viability. Development of a clinical training guide for medical physicists specialising in nuclear medicine was started in 2009 with the appointment of a core drafting committee of regional and international experts. The publication drew on the experience of clinical training in Australia, Croatia and Sweden and was moderated by physicists working in the Asian region. The present publication follows the approach of earlier IAEA publications in the Training Course Series, specifically Nos 37 and 47, Clinical Training of Medical Physicists Specializing in Radiation Oncology and Clinical Training of Medical Physicists

  16. Recent developments and future trends in nuclear medicine instrumentation.

    Science.gov (United States)

    Zaidi, Habib

    2006-01-01

    Molecular imaging using high-resolution single-photon emission computed tomography (SPECT) and positron emission tomography (PET) has advanced elegantly and has steadily gained importance in the clinical and research arenas. Continuous efforts to integrate recent research findings for the design of different geometries and various detector technologies of SPECT and PET cameras have become the goal of both the academic comcameras have become the goal of both the academic community and nuclear medicine industry. As PET has recently become of more interest for clinical practice, several different design trends seem to have developed. Systems are being designed for "low cost" clinical applications, very high-resolution research applications (including small-animal imaging), and just about everywhere in-between. The development of dual-modality imaging systems has revolutionized the practice of nuclear medicine. The major advantage being that SPECT/PET data are intrinsically aligned to anatomical information from the X-ray computed tomography (CT), without the use of external markers or internal landmarks. On the other hand, combining PET with Magnetic Resonance Imaging (MRI) technology is scientifically more challenging owing to the strong magnetic fields. Nevertheless, significant progress has been made resulting in the design of a prototype small animal PET scanner coupled to three multichannel photomultipliers via optical fibers, so that the PET detector can be operated within a conventional MR system. Thus, many different design paths are being pursued--which ones are likely to be the main stream of future commercial systems? It will be interesting, indeed, to see which technologies become the most popular in the future. This paper briefly summarizes state-of-the art developments in nuclear medicine instrumentation. Future prospects will also be discussed. PMID:16696367

  17. Recent developments and future trends in nuclear medicine instrumentation

    International Nuclear Information System (INIS)

    Molecular imaging using high-resolution single-photon emission computed tomography (SPECT) and positron emission tomography (PET) has advanced elegantly and has steadily gained importance in the clinical and research arenas. Continuous efforts to integrate recent research findings for the design of different geometries and various detector technologies of SPECT and PET cameras have become the goal of both the academic community and nuclear medicine industry. As PET has recently become of more interest for clinical practice, several different design trends seem to have developed. Systems are being designed for ''low cost'' clinical applications, very high-resolution research applications (including small-animal imaging), and just about everywhere in-between. The development of dual-modality imaging systems has revolutionized the practice of nuclear medicine. The major advantage being that SPECT/PET data are intrinsically aligned to anatomical information from the X-ray computed tomography (CT), without the use of external markers or internal landmarks. On the other hand, combining PET with magnetic resonance imaging (MRI) technology is scientifically more challenging owing to the strong magnetic fields. Nevertheless, significant progress has been made resulting in the design of a prototype small animal PET scanner coupled to three multichannel photomultipliers via optical fibers, so that the PET detector can be operated within a conventional MR system. Thus, many different design paths are being pursued - which ones are likely to be the main stream of future commercial systems? It will be interesting, indeed, to see which technologies become the most popular in the future. This paper briefly summarizes state-of-the art developments in nuclear medicine instrumentation. Future prospects will also be discussed. (orig.)

  18. Terbium-149 for nuclear medicine. The production of 149Tb via heavy ions induced nuclear reactions

    International Nuclear Information System (INIS)

    Experimental results on the production and separation of 149Tb from natural neodymium target using the nuclear process Nd(12C,xn)149Dy → 149Tb are presented. Terbium-149 was produced at the U-200 cyclotron of FLNR JINR by irradiating natNd2O3 with 12C ions and its possible production for nuclear medicine utilising the heavy-ion induced reactions was investigated. (author)

  19. Nuclear Medicine in Thyroid Diseases in Pediatric and Adolescent Patients

    Directory of Open Access Journals (Sweden)

    Bilge Volkan-Salancı

    2015-06-01

    Full Text Available Both benign and malignant diseases of the thyroid are rare in the pediatric and adolescent population, except congenital hypothyroidism. Nuclear medicine plays a major role, both in the diagnosis and therapy of thyroid pathologies. Use of radioactivity in pediatric population is strictly controlled due to possible side effects such as secondary cancers; therefore, management of pediatric patients requires detailed literature knowledge. This article aims to overview current algorithms in the management of thyroid diseases and use of radionuclide therapy in pediatric and adolescent population.

  20. Nuclear medicine for diagnostic evaluation of osteomyelitis in children

    International Nuclear Information System (INIS)

    Although skeletal scintiscanning has yielded results allowing an early diagnosis of osteomyelitis in children already at a stage prior to detection by X-ray radiography, reports have been published showing that there is quite a number of false negative findings obtained by nuclear medicine techniques, especially in newborns. The article here therefore reports a study on clinical validation of skeletal scintigraphy in case of suspected osteomyelitis in children. The results show that scintiscanning is a very sensitive method of detecting osteomyelitis in children, and also can be a very useful diagnostic tool for examination of newborns, provided the different anatomy of the skeleton in newborns is taken into account. (orig./MG)