WorldWideScience

Sample records for cardiovascular behavior perspectives

  1. Down Syndrome: A Cardiovascular Perspective

    Science.gov (United States)

    Vis, J. C.; Duffels, M. G. J.; Winter, M. M.; Weijerman, M. E.; Cobben, J. M.; Huisman, S. A.; Mulder, B. J. M.

    2009-01-01

    This review focuses on the heart and vascular system in patients with Down syndrome. A clear knowledge on the wide spectrum of various abnormalities associated with this syndrome is essential for skillful management of cardiac problems in patients with Down syndrome. Epidemiology of congenital heart defects, cardiovascular aspects and…

  2. Patient perspective on remote monitoring of cardiovascular implantable electronic devices

    DEFF Research Database (Denmark)

    Versteeg, H; Pedersen, Susanne S.; Mastenbroek, M H;

    2014-01-01

    BACKGROUND: Remote patient monitoring is a safe and effective alternative for the in-clinic follow-up of patients with cardiovascular implantable electronic devices (CIEDs). However, evidence on the patient perspective on remote monitoring is scarce and inconsistent. OBJECTIVES: The primary...

  3. Central neural control of the cardiovascular system: current perspectives.

    Science.gov (United States)

    Dampney, Roger A L

    2016-09-01

    This brief review, which is based on a lecture presented at the American Physiological Society Teaching Refresher Course on the Brain and Systems Control as part of the Experimental Biology meeting in 2015, aims to summarize current concepts of the principal mechanisms in the brain that regulate the autonomic outflow to the cardiovascular system. Such cardiovascular regulatory mechanisms do not operate in isolation but are closely coordinated with respiratory and other regulatory mechanisms to maintain homeostasis. The brain regulates the cardiovascular system by two general means: 1) feedforward regulation, often referred to as "central command," and 2) feedback or reflex regulation. In most situations (e.g., during exercise, defensive behavior, sleep, etc.), both of these general mechanisms contribute to overall cardiovascular homeostasis. The review first describes the mechanisms and central circuitry subserving the baroreceptor, chemoreceptor, and other reflexes that work together to regulate an appropriate level of blood pressure and blood oxygenation and then considers the brain mechanisms that defend the body against more complex environmental challenges, using dehydration and cold and heat stress as examples. The last section of the review considers the central mechanisms regulating cardiovascular function associated with different behaviors, with a specific focus on defensive behavior and exercise. PMID:27445275

  4. Time Perspective in Consumer Behavior

    Czech Academy of Sciences Publication Activity Database

    Klicperová-Baker, Martina; Košťál, Jaroslav; Vinopal, Jiří

    New York : Springer, 2015 - (Stolarski, M.; Fieulaine, N.; van Beek, W.), s. 353-369 ISBN 978-3-319-07367-5 Institutional support: RVO:68081740 ; RVO:68378025 Keywords : ZTPI * time perspective * consumer behavior Subject RIV: AN - Psychology; AO - Sociology, Demography (SOU-Z)

  5. Time Perspective in Consumer Behavior

    Czech Academy of Sciences Publication Activity Database

    Klicperová-Baker, Martina; Košťál, Jaroslav; Vinopal, Jiří

    New York: Springer, 2015 - (Stolarski, M.; Fieulaine, N.; van Beek, W.), s. 353-369 ISBN 978-3-319-07367-5 Institutional support: RVO:68081740 ; RVO:68378025 Keywords : ZTPI * time perspective * consumer behavior Subject RIV: AN - Psychology; AO - Sociology, Demography (SOU-Z)

  6. Market segmentation in behavioral perspective.

    OpenAIRE

    Wells, V.K.; Chang, S W; Oliveira-Castro, J.M.; J. Pallister

    2010-01-01

    A segmentation approach is presented using both traditional demographic segmentation bases (age, social class/occupation, and working status) and a segmentation by benefits sought. The benefits sought in this case are utilitarian and informational reinforcement, variables developed from the Behavioral Perspective Model (BPM). Using data from 1,847 consumers and from a total of 76,682 individual purchases, brand choice and price and reinforcement responsiveness were assessed for each segment a...

  7. Work stress and cardiovascular disease: a life course perspective.

    Science.gov (United States)

    Li, Jian; Loerbroks, Adrian; Bosma, Hans; Angerer, Peter

    2016-05-25

    Individuals in employment experience stress at work, and numerous epidemiological studies have documented its negative health effects, particularly on cardiovascular disease (CVD). Although evidence on the various interrelationships between work stress and CVD has been accumulated, those observations have not yet been conceptualized in terms of a life course perspective. Using the chain of risk model, we would like to propose a theoretical model incorporating six steps: (1) work stress increases the risk of incident CVD in healthy workers. (2) Among those whose work ability is not fully and permanently damaged, work stress acts as a determinant of the process of return to work after CVD onset. (3) CVD patients experience higher work stress after return to work. (4) Work stress increases the risk of recurrent CVD in workers with prior CVD. (5) CVD patients who fully lose their work ability transit to disability retirement. (6) Disability retirees due to CVD have an elevated risk of CVD mortality. The life course perspective might facilitate an in-depth understanding of the diverse interrelationships between work stress and CVD, thereby leading to work stress management interventions at each period of the lifespan and three-level prevention of CVD. PMID:27010081

  8. Klotho in cardiovascular disease:Current and future perspectives

    Institute of Scientific and Technical Information of China (English)

    Javier; Donate-Correa; Ernesto; Martín-Nú?ez; Carmen; Mora-Fernández; Mercedes; Muros-de-Fuentes; Nayra; Pérez-Delgado; Juan; F; Navarro-González

    2015-01-01

    Protein Klotho,beyond its role as a regulator of the phosphatemia,is also involved in the maintaining of the cardiovascular health,being associated its alterations with the development of cardiovascular damage and increased morbi-mortality. For all this,nowadays Klotho is the subject of a thorough research which is focused on uncover its intimate mechanisms of action,and in analyzing the utility of its modulation as a potential strategy with clinical applicability. Molecular mechanisms of Klotho are not well understood but an emerging research area links Klotho deficiency with vascular pathology. Changes in this protein have been associated with cardiovascular-related complications like inflammation,vascular calcification,and endothelial dysfunction. All this is particularly relevant if considering the recent discovery of Klotho expression in vascular tissue.

  9. A clinical perspective of obesity, metabolic syndrome and cardiovascular disease.

    Science.gov (United States)

    Han, Thang S; Lean, Mike Ej

    2016-01-01

    The metabolic syndrome is a condition characterized by a special constellation of reversible major risk factors for cardiovascular disease and type 2 diabetes. The main, diagnostic, components are reduced HDL-cholesterol, raised triglycerides, blood pressure and fasting plasma glucose, all of which are related to weight gain, specifically intra-abdominal/ectopic fat accumulation and a large waist circumference. Using internationally adopted arbitrary cut-off values for waist circumference, having metabolic syndrome doubles the risk of cardiovascular disease, but offers an effective treatment approach through weight management. Metabolic syndrome now affects 30-40% of people by age 65, driven mainly by adult weight gain, and by a genetic or epigenetic predisposition to intra-abdominal/ectopic fat accumulation related to poor intra-uterine growth. Metabolic syndrome is also promoted by a lack of subcutaneous adipose tissue, low skeletal muscle mass and anti-retroviral drugs. Reducing weight by 5-10%, by diet and exercise, with or without, anti-obesity drugs, substantially lowers all metabolic syndrome components, and risk of type 2 diabetes and cardiovascular disease. Other cardiovascular disease risk factors such as smoking should be corrected as a priority. Anti-diabetic agents which improve insulin resistance and reduce blood pressure, lipids and weight should be preferred for diabetic patients with metabolic syndrome. Bariatric surgery offers an alternative treatment for those with BMI ≥ 40 or 35-40 kg/m(2) with other significant co-morbidity. The prevalence of the metabolic syndrome and cardiovascular disease is expected to rise along with the global obesity epidemic: greater emphasis should be given to effective early weight-management to reduce risk in pre-symptomatic individuals with large waists. PMID:26998259

  10. Perspectives on Vocational Behavior, 1986: A Review.

    Science.gov (United States)

    Slaney, Robert B.; Russell, Joyce E. A.

    1987-01-01

    Based on perspectives of counseling psychology and industrial/organizational psychology, this article reviews publications relevant to vocational behavior that appeared during 1986. Of the over 700 articles and 70 books or book chapters located, slightly less than one-half are reviewed. (Author/NB)

  11. Market Segmentation from a Behavioral Perspective

    Science.gov (United States)

    Wells, Victoria K.; Chang, Shing Wan; Oliveira-Castro, Jorge; Pallister, John

    2010-01-01

    A segmentation approach is presented using both traditional demographic segmentation bases (age, social class/occupation, and working status) and a segmentation by benefits sought. The benefits sought in this case are utilitarian and informational reinforcement, variables developed from the Behavioral Perspective Model (BPM). Using data from 1,847…

  12. Poverty, malnutrition, underdevelopment and cardiovascular disease: a South African perspective

    OpenAIRE

    Vorster, HH; Kruger, A.

    2007-01-01

    Summary Summary This article explores possible mechanisms to explain the known relationships between poverty, undernutrition, underdevelopment and cardiovascular disease (CVD) in developing countries. Poverty is a multidimensional concept. It is both a cause and consequence of undernutrition. The article shows how malnutrition during pregnancy could lead to low birth-weight babies, who are not only at increased risk of mental and physical underdevelopment, but also ‘programmed’ to be at incre...

  13. ENTREPRENEURSIPH IN ROMANIA. A BEHAVIORAL ECONOMICS PERSPECTIVE

    OpenAIRE

    Neațu Alina-Maria; Imbrișcă Cosmin-Ionuț

    2015-01-01

    Economics provides insight into how entrepreneurship influences growth and development and, on the other hand, how the macro structure of a region or country impacts the type and abundance of entrepreneurship. Economic analysis provides insights for scholars, guides practitioners and policymakers. From a broader perspective, economic theories guide the understanding of human behaviors and the constant quest toward realization, comprehension and improvement of human condition. Moreover, behavi...

  14. ENTREPRENEURSIPH IN ROMANIA. A BEHAVIORAL ECONOMICS PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Neațu Alina-Maria

    2015-07-01

    Full Text Available Economics provides insight into how entrepreneurship influences growth and development and, on the other hand, how the macro structure of a region or country impacts the type and abundance of entrepreneurship. Economic analysis provides insights for scholars, guides practitioners and policymakers. From a broader perspective, economic theories guide the understanding of human behaviors and the constant quest toward realization, comprehension and improvement of human condition. Moreover, behavioral economics combines insights of psychology, sociology and economics in trying to better understand and predict human decision-making. At the intersection of economic studies with social sciences, behavioral economics succeeds to demonstrate, using laboratory tests and experiments, that on a shorter term people are quite capable to perform profitable economic computations and adopt rational behaviors, but on a long term run they easily become fallible in performing rational mental accounting and are vulnerable to several factors such as emotions, certain mass-manipulation techniques, lack of self control or procrastination, etc. Extended research in the field of behavioral economics reports many other various behavioral anomalies that may have the ability to explain seemingly irrational and unpredictable responses of individuals, in general, and entrepreneurs, in particular – especially when finding themselves in conditions of risk, uncertainty or incomplete information. Furthermore, the elevated consistency of these abnormalities suggests that they are divergent only to our traditional models, but that they could otherwise be the norm. The present article seeks to explain how such insights from behavioral economics may help us better understand and enhance our perspective on entrepreneurship, what are some of the most frequent biases characteristic to entrepreneurial behavior and decision-making, accounting as most notable for the field of

  15. Terrorism in Pakistan: a behavioral sciences perspective.

    Science.gov (United States)

    Nizami, Asad Tamizuddin; Rana, Mowadat Hussain; Hassan, Tariq Mahmood; Minhas, Fareed Aslam

    2014-01-01

    This article reviews the behavioral science perspectives of terrorism in Pakistan. It can be argued that Pakistan has gained worldwide attention for "terrorism" and its role in the "war against terrorism". The region is well placed geopolitically for economic successes but has been plagued by terrorism in various shapes and forms. A behavioral sciences perspective of terrorism is an attempt to explain it in this part of the world as a complex interplay of historical, geopolitical, anthropological and psychosocial factors and forces. Drawing from theories by Western scholars to explain the behavioral and cognitive underpinnings of a terrorist mind, the authors highlight the peculiarities of similar operatives at individual and group levels. Thorny issues related to the ethical and human right dimensions of the topic are visited from the unique perspective of a society challenged by schisms and divergence of opinions at individual, family, and community levels. The authors have attempted to minimize the political descriptions, although this cannot be avoided entirely, because of the nature of terrorism. PMID:24777397

  16. Nutrition and cardiovascular disease: an Asia Pacific perspective.

    Science.gov (United States)

    Khor, G L

    1997-06-01

    Changes in the dietary intake patterns of countries in the Asia Pacific region are considered in relation to trends of cardiovascular disease mortality. Cardiovascular disease now constitutes the major cause of mortality in many of the countries of the region. The mortality rate for coronary heart disease (CHD) has been on the decline since the mid-1960s in countries such as Australia, New Zealand and Japan, while a decline in other countries, including Singapore and Hong Kong, appears to be occurring about two decades later after a delayed increase. In contrast, countries like Malaysia and China have had and continue an upward trend for CHD mortality. Nonetheless, the mortality rates due to CHD in New Zealand, Australia, Singapore followed by Hong Kong rank among the highest in the region. In China, Taiwan and Japan, death due to cerebrovascular disease remains a major cause of death, although the latter two countries have undergone a significant decline in stroke death rates since 1970. The intakes of fat from land animal products, fish and vegetable oils, depending on fatty acid patterns and, possibly other constituents, are candidate contributors to the different atherogenic and thrombotic effects. Countries which have a higher mortality from CHD tend to have a higher intake of energy from fat and proportion of fat from animal products. These fat intakes may operate to increase hypercholesterolemia and overweight in various countries. Again, intakes of other food items and constituents used in the region such as soybeans, dietary antioxidants in fruits, vegetables, seeds, cereals, nuts and tea and alcohol consumption are candidate cardio-protectants. The wide dietary scope of Asia Pacific populations, from diverse socio-cultural backgrounds, and at different levels of economic and technological development poses several analytic challenges and opportunities. Future research should improve the datasets and think laterally about pathogenesis and intervention

  17. Cardiovascular disease risk factors for women. A life course-events perspective

    Directory of Open Access Journals (Sweden)

    Arora Chander P.

    2010-04-01

    Full Text Available Cardiovascular disease (CVD in women is the most common cause of death and in 2009 accounted for one third of all deaths. The purpose of this paper is to present what conditions during pregnancy and during the pre-menopause period lead to a greater risk of CVD. The early recognition and the application of interventions may decrease this risk. To emphasize this point we have taken a «Life course-events perspective». Current data suggests that genetic predisposition to disease in conjunction with behavior and environmental factors during fetal life is related to permanent changes in fetalplacental-maternal physiology and function, resulting in fetal programming characterizing the phenotype of the child which may persist into adulthood. Longitudinal studies have identified biological, behavioral and environmental factors related to childhood diseases such as hypertension, insulin resistance and mental health disorders. Gender differences have been identified and animal studies have suggested that estrogens in women are protective and when the risk of CVD in men is considered, the risk in women is delayed by 10 years. Thus, a normal pregnancy may be protective and reduce the risk of CVD in women. However, hypertension developing in women before or during pregnancy is a significant risk factor for women and diabetes further increases this risk of CVD, as does smoking. It is very clear that an «intervention action plan» must be developed. It is the current opinion of the authors that this action plan must be implemented early in life to decrease the risk for the development of CVS in women.

  18. Association of sedentary behavior time with ideal cardiovascular health: the ORISCAV-LUX study.

    Directory of Open Access Journals (Sweden)

    Georgina E Crichton

    Full Text Available Recently attention has been drawn to the health impacts of time spent engaging in sedentary behaviors. No studies have examined sedentary behaviors in relation to the newly defined construct of ideal cardiovascular health, which incorporates three health factors (blood pressure, total cholesterol, fasting plasma glucose and four behaviors (physical activity, smoking, body mass index, diet. The purpose of this study was to examine associations between sedentary behaviors, including sitting time, and time spent viewing television and in front of a computer, with cardiovascular health, in a representative sample of adults from Luxembourg.A cross-sectional analysis of 1262 participants in the Observation of Cardiovascular Risk Factors in Luxembourg study was conducted, who underwent objective cardiovascular health assessments and completed the International Physical Activity Questionnaire. A Cardiovascular Health Score was calculated based on the number of health factors and behaviors at ideal levels. Sitting time on a weekday, television time, and computer time (both on a workday and a day off, were related to the Cardiovascular Health Score.Higher weekday sitting time was significantly associated with a poorer Cardiovascular Health Score (p = 0.002 for linear trend, after full adjustment for age, gender, education, income and occupation. Television time was inversely associated with the Cardiovascular Health Score, on both a workday and a day off (p = 0.002 for both. A similar inverse relationship was observed between the Cardiovascular Health Score and computer time, only on a day off (p = 0.04.Higher time spent sitting, viewing television, and using a computer during a day off may be unfavorably associated with ideal cardiovascular health.

  19. Poverty, malnutrition, underdevelopment and cardiovascular disease: a South African perspective.

    Science.gov (United States)

    Vorster, H H; Kruger, A

    2007-01-01

    This article explores possible mechanisms to explain the known relationships between poverty, undernutrition, underdevelopment and cardiovascular disease (CVD) in developing countries. Poverty is a multidimensional concept. It is both a cause and consequence of undernutrition. The article shows how malnutrition during pregnancy could lead to low birth-weight babies, who are not only at increased risk of mental and physical underdevelopment, but also 'programmed' to be at increased risk of CVD and other non-communicable diseases in adult life. The underdevelopment leads to decreased 'human capital and competence' with an inability to create food security and an enabling environment for self and family to escape poverty and undernutrition in the next generation. It is accepted that a lack of education and knowledge in the poor for primary prevention of CVD through healthy eating patterns and lifestyles, as well as limited access to healthcare services for secondary prevention and treatment contribute to CVD. This article postulates that the link between poverty and CVD in South Africa can be explained by the high prevalence of undernutrition in one- to nine year- old children (9% underweight, 23% stunted and 3% wasted), the high prevalence of overweight and obesity in adults (54.5% in white men and 58.5% in African women) as well as the negative trends in nutrient intakes when Africans (the population group with the largest numbers of poor people) urbanise, acculturate and adopt westernised eating patterns that will increase CVD risk. In conclusion, we plead for a holistic, integrated but transdisciplinary and multisectorial approach to break the vicious circle of poverty and undernutrition for the longterm prevention of CVD. PMID:17985032

  20. Information-seeking behavior of cardiovascular disease patients in Isfahan University of Medical Sciences hospitals

    OpenAIRE

    Zamani, Maryam; Soleymani, Mohammad Reza; Afshar, Mina; Shahrzadi, Leila; Zadeh, Akbar Hasan

    2014-01-01

    Background: Patients, as one of the most prominent groups requiring health-based information, encounter numerous problems in order to obtain these pieces of information and apply them. The aim of this study was to determine the information-seeking behavior of cardiovascular patients who were hospitalized in Isfahan University of Medical Sciences hospitals. Materials and Methods: This is a survey research. The population consisted of all patients with cardiovascular disease who were hospitaliz...

  1. Cardiovascular disease risk factors for women. A life course-events perspective

    OpenAIRE

    Arora Chander P.; Hobel C. J.

    2010-01-01

    Cardiovascular disease (CVD) in women is the most common cause of death and in 2009 accounted for one third of all deaths. The purpose of this paper is to present what conditions during pregnancy and during the pre-menopause period lead to a greater risk of CVD. The early recognition and the application of interventions may decrease this risk. To emphasize this point we have taken a «Life course-events perspective». Current data suggests that genetic predisposition to disease in conjunction w...

  2. Associations Between Screen-Based Sedentary Behavior and Cardiovascular Disease Risk Factors in Korean Youth

    OpenAIRE

    Byun, Wonwoo; Dowda, Marsha; Pate, Russell R.

    2012-01-01

    The purposes of this study were to: 1) describe the patterns of screen-based sedentary behaviors, and 2) examine the association between screen-based sedentary behavior and cardiovascular disease (CVD) risk factors in representative Korean children and adolescents, aged 12 to 18 yr, in the Korean National Health and Nutrition Examination Survey. Screen-based sedentary behavior was measured using self-report questionnaires that included items for time spent watching TV and playing PC/video gam...

  3. Incidence of behavior's habits in the cardiovascular disease prevention

    NARCIS (Netherlands)

    Carpi-Ballester, Amparo; Zurriaga-Llorens, Rosario; Gonzalez-Navarro, Pilar; Marzo-Campos, Juan C.; Buunk, Abraham P.

    2007-01-01

    Different models have been proposed from Health Psychology in order to understand and to predict healthy behaviours. Theory of Planed Behavior is a prevailing model in the study of health. Using this theoretical framework, the objective of this descriptive study is to test the impact of behavioral h

  4. Stem cell therapy for cardiovascular disease : answering basic questions regarding cell behavior

    NARCIS (Netherlands)

    Bogt, Koen Elzert Adriaan van der

    2010-01-01

    Stem cell therapy has raised enthusiasm as a potential treatment for cardiovascular diseases. However, questions remain about the in vivo behavior of the cells after transplantation and the mechanism of action with which the cells could potentially alleviate disease symptoms. The objective of the re

  5. Return on Investment for Digital Behavioral Counseling in Patients With Prediabetes and Cardiovascular Disease

    Directory of Open Access Journals (Sweden)

    Wenqing Su, MS

    2016-01-01

    Full Text Available Introduction We calculated the health and economic impacts of participation in a digital behavioral counseling service that is designed to promote a healthful diet and physical activity for cardiovascular disease prevention in adults with prediabetes and cardiovascular disease risk factors (Prevent, Omada Health, San Francisco, California. This program enhances the Centers for Disease Control and Prevention’s Diabetes Prevention Recognition Program. Participants completed a 16-week core program followed by an ongoing maintenance program. Methods Analysis was conducted for 2 populations meeting criteria for lifestyle intervention: 1 prediabetes (n = 1,663, and 2 high cardiovascular disease risk (n = 2,152. The Markov-based model simulated clinical and economic outcomes related to obesity and diabetes annually over 10 years for the 2 defined populations. Comparisons were made between participants and propensity-matched controls from the community. Results The return-on-investment break-even point was 3 years in both populations. Simulated return on investment for the population with prediabetes was $9 and $1,565 at years 3 and 5, respectively. Simulated return on investment for the population with cardiovascular disease risk was $96 and $1,512 at years 3 and 5, respectively. Results suggest that program participation reduces diabetes incidence by 30% to 33% and stroke by 11% to 16% over 5 years. Conclusion Digital Behavioral Counseling provides significant health benefits to patients with prediabetes and cardiovascular disease and a positive return on investment.

  6. An Evolutionary Perspective of Nutrition and Inflammation as Mechanisms of Cardiovascular Disease

    Directory of Open Access Journals (Sweden)

    María Esther Rubio-Ruiz

    2015-01-01

    Full Text Available When cardiovascular diseases are viewed from an evolutionary biology perspective, a heightened thrifty and an inflammatory design could be their mechanisms. Human ancestors confronted a greater infectious load and were subjected to the selection for proinflammatory genes and a strong inflammatory function. Ancestors also faced starvation periods that pressed for a thrifty genotype which caused fat accumulation. The pressure of sustaining gluconeogenesis during periods of poor nourishment selected individuals with insulin resistance. Obesity induces a proinflammatory state due to the secretion of adipokines which underlie cardiometabolic diseases. Our actual lifestyle needs no more of such proinflammatory and thrifty genotypes and these ancestral genes might increase predisposition to diseases. Risk factors for atherosclerosis and diabetes are based on inflammatory and genetic foundations that can be accounted for by excess fat. Longevity has also increased in recent times and is related to a proinflammatory response with cardiovascular consequences. If human ancestral lifestyle could be recovered by increasing exercise and adapting a calorie restriction diet, obesity would decrease and the effects on chronic low-grade inflammation would be limited. Thereby, the rates of both atherosclerosis and diabetes could be reduced.

  7. Trauma and Psychotherapy: Implications from a Behavior Analysis Perspective

    Science.gov (United States)

    Prather, Walter

    2007-01-01

    Attachment theory provides a useful conceptual framework for understanding trauma and the treatment of abuse in children. This article examines attachment theory and traditional models of family therapy from the perspective of behavior analysis, and provides a rationale for a behavioral treatment approach for abused children and their foster or…

  8. Perspective Taking, Empathy, and Prosocial Behavior in Late Childhood.

    Science.gov (United States)

    Bengtsson, Hans; Johnson, Lena

    1992-01-01

    Examined the relationship between perspective taking in response to another's distress and prosocial behavior and dispositional affective empathy in late childhood. The tendency to reflect spontaneously on the inner experience of others who are unfortunate was positively related to prosocial behavior in boys and to affective empathy in both sexes.…

  9. Cardiac risk factors: environmental, sociodemographic, and behavioral cardiovascular risk factors.

    Science.gov (United States)

    Anthony, David; George, Paul; Eaton, Charles B

    2014-06-01

    Several environmental exposures are associated with increased risk of coronary heart disease (CHD). Exposure to secondhand smoke may increase the risk by as much as 25% to 30%. Exposure to third hand smoke, residual components of tobacco smoke that remain in the environment after a cigarette is extinguished, also appears to increase risk. These residual components can remain in rooms and automobiles for up to 30 years and enter the body through the skin or via inhalation or ingestion. Exposure to particulate matter air pollution from automobile emissions, power plants, and other sources is yet another environmental risk factor for CHD, resulting in tens of thousands of deaths annually in the United States. Exposure to other environmental toxins, particularly bisphenol A and phthalates, also has been linked to CHD. There are sociodemographic risks for CHD, with numerous studies showing that lower socioeconomic status is associated with higher risk. Behavioral risk factors include poor diet, such as frequent consumption of fast food and processed meals; sleep disturbance; and psychological stress, particularly related to marital or work issues. Finally, although high alcohol consumption is associated with increased CHD risk, moderate alcohol consumption (ie, less than 1 to 2 drinks/day), particularly of wine and possibly beer, appears to reduce the risk. PMID:24936715

  10. Adaptation and development of software simulation methodologies for cardiovascular engineering: present and future challenges from an end-user perspective.

    Science.gov (United States)

    Díaz-Zuccarini, V; Narracott, A J; Burriesci, G; Zervides, C; Rafiroiu, D; Jones, D; Hose, D R; Lawford, P V

    2009-07-13

    This paper describes the use of diverse software tools in cardiovascular applications. These tools were primarily developed in the field of engineering and the applications presented push the boundaries of the software to address events related to venous and arterial valve closure, exploration of dynamic boundary conditions or the inclusion of multi-scale boundary conditions from protein to organ levels. The future of cardiovascular research and the challenges that modellers and clinicians face from validation to clinical uptake are discussed from an end-user perspective. PMID:19487202

  11. Efficacy of Dietary Behavior Modification for Preserving Cardiovascular Health and Longevity

    OpenAIRE

    Moira McAllister Pryde; William Bernard Kannel

    2011-01-01

    Cardiovascular disease (CVD) and its predisposing risk factors are major lifestyle and behavioral determinants of longevity. Dietary lifestyle choices such as a heart healthy diet, regular exercise, a lean weight, moderate alcohol consumption, and smoking cessation have been shown to substantially reduce CVD and increase longevity. Recent research has shown that men and women who adhere to this lifestyle can substantially reduce their risk of coronary heart disease (CHD). The preventive bene...

  12. THE CONCEPT OF MEANING FROM BEHAVIOR ANALYSIS AND OTHER PERSPECTIVES.

    OpenAIRE

    BLANCA PATRICIA BALLESTEROS DE VALDERRAMA

    2005-01-01

    This article presents crucial points related to the concept of meaning trying to emphasize some convergences betweenbehavior analysis, other behavioral perspectives, like Staats’ and Ribes-Iñesta’s, and postures outside behaviorism,specially those made by J. Bruner and other representatives of constructivism and constructionism. DeGrandpre(2000) presented some ways how behaviorism can contribute to the “science of meaning” and the “psychology ofpractical significance”; his suggestions are com...

  13. Antisocial behavior from a developmental psychopathology perspective

    OpenAIRE

    Frick, P. J.; Viding, E.

    2009-01-01

    This paper reviews research on chronic patterns of antisocial behavior and places this research into a developmental psychopathology framework. Specifically, research suggests that there are at least three important pathways through which children and adolescents can develop severe antisocial behaviors. One group of youth shows antisocial behavior that begins in adolescence, and two groups show antisocial behavior that begins in childhood but differ on the presence or absence of callous-unemo...

  14. Behavioral targeting: a European legal perspective

    NARCIS (Netherlands)

    F. Zuiderveen Borgesius

    2013-01-01

    Behavioral targeting, or online profiling, is a hotly debated topic. Much of the collection of personal information on the Internet is related to behavioral targeting, although research suggests that most people don't want to receive behaviorally targeted advertising. The World Wide Web Consortium i

  15. Heme Oxygenase-1 in Cardiovascular Diseases: Molecular Mechanisms and Clinical Perspectives

    Directory of Open Access Journals (Sweden)

    Chao-Yung Wang

    2010-02-01

    Full Text Available Heme oxygenase (HO catalyzes the rate-limiting step inthe oxidative degradation of cellular heme that liberates iron,carbon monoxide (CO, and biliverdin. Two distinct HO isoformshave been identified in mammalian system. Comparedto HO-2, which is constitutively expressed, HO-1 is a stressresponsiveprotein that is highly induced by many agents,including cytokines, endotoxin, heavy metals, nitric oxide andits own substrate heme. In addition to its well-defined role inheme catabolism and erythrocyte turnover, HO-1 also plays animportant function in various physiological and pathophysiologicalstates associated with cellular stress. Over the pastdecade, compelling evidence has revealed that the induction ofHO-1 represents an important defensive mechanism againstfurther oxidative injury in tissues and cells following variousinsults; this occurs by virtue of the anti-inflammatory andantioxidant capacities of CO, biliverdin, and the subsequent metabolite of biliverdin, bilirubin.In line with the findings from the basic research, numerous studies have supported theimportance of HO-1 in various clinical diseases, including coronary artery disease, cardiachypertrophy, diabetes mellitus, ischemic/reperfusion injury, atherosclerosis and cancer. Thisreview provides an overview on the regulation and function of HO-1, ranging from the molecularmechanisms involved to various clinical perspectives. Specifically, there is a focus onthe enzyme’s role in various cardiovascular diseases.

  16. Subtypes of Aggressive Behaviors: A Developmental Perspective

    Science.gov (United States)

    Vitaro, Frank; Brendgen, Mara; Barker, Edward D.

    2006-01-01

    Aggressive behaviors in children and adolescents have undergone important conceptual and definitional modifications in the past two decades. In particular, subtypes of aggression have been proposed that separate the form and the function of the aggressive behaviors (i.e., social vs. physical aggression; reactive vs. proactive aggression).…

  17. Parents as Behavioral Change Agents: New Perspectives.

    Science.gov (United States)

    Simpson, Richard L.

    This paper presents a model for school psychologists to instruct parents in behavior modification procedures for use with their children. This model, designed for use by individuals who have a basic working knowledge of operant conditioning and applied behavior analysis procedures, consists of three training sessions which are outlined with…

  18. A Selectionist Perspective on Systemic and Behavioral Change in Organizations

    Science.gov (United States)

    Sandaker, Ingunn

    2009-01-01

    This article provides a discussion of how different dynamics in production processes and communication structures in the organization serve as different environmental contingencies favoring different behavioral patterns and variability of performance in organizations. Finally, an elaboration on a systems perspective on the selection of corporate…

  19. Advertising and obesity: a behavioral perspective.

    Science.gov (United States)

    Hoek, Janet; Gendall, Philip

    2006-06-01

    Concern over the levels of obesity observed in Western countries has grown as researchers forecast a rapid growth in the medical care that a progressively more obese population will require. As health workers deal with increased incidences of diabetes and other obesity-related disorders, policymakers have examined the factors contributing to this problem. In particular, advertising that promotes high fat and high sugar products to children has come under increasing scrutiny. Advertisers have rejected claims that advertising contributes to obesity by arguing that it cannot coerce people into purchasing a product, and does not affect primary demand. This reasoning overlooks the role advertising plays in reinforcing and normalising behavior, however, and it assumes that only direct causal links merit regulatory attention. Ehrenberg's "weak" theory suggests advertising will support unhealthy eating behaviors, while the wide range of sales promotions employed will prompt trial and reward continued consumption. This article presents an alternative analysis of how marketing contributes to obesity and uses behavior modification theory to analyse the "fast-food" industry's promotions. We also review the New Zealand government's response to obesity and suggest policy interventions that would foster healthier eating behaviors. PMID:16720538

  20. Research on Vocational Behavior: The Singapore Perspective.

    Science.gov (United States)

    Tan, Esther

    1998-01-01

    This review of vocational psychology research in Singapore, 1985 to 1997, addresses career development, interests, sex stereotypes, work values, job satisfaction, and home/family influence. The review shows an increase in research on school-aged populations and a need to study the vocational behavior of the work force. (SK)

  1. Economic Cycles in a Behavioral Disequilibrium Perspective

    DEFF Research Database (Denmark)

    Mosekilde, Erik; Sterman, J.D.

    1997-01-01

    The paper reviews the characteristic features of the main economic cycles and discusses the behavioral foundation for each mode at the microlevel. The analysis continues to illustrate some of the nonlinear dynamic phenomena that can arise through interaction between the various modes and through...

  2. Longitudinal Effects of Embryonic Exposure to Cocaine on Morphology, Cardiovascular Physiology, and Behavior in Zebrafish.

    Science.gov (United States)

    Mersereau, Eric J; Boyle, Cody A; Poitra, Shelby; Espinoza, Ana; Seiler, Joclyn; Longie, Robert; Delvo, Lisa; Szarkowski, Megan; Maliske, Joshua; Chalmers, Sarah; Darland, Diane C; Darland, Tristan

    2016-01-01

    A sizeable portion of the societal drain from cocaine abuse results from the complications of in utero drug exposure. Because of challenges in using humans and mammalian model organisms as test subjects, much debate remains about the impact of in utero cocaine exposure. Zebrafish offer a number of advantages as a model in longitudinal toxicology studies and are quite sensitive physiologically and behaviorally to cocaine. In this study, we have used zebrafish to model the effects of embryonic pre-exposure to cocaine on development and on subsequent cardiovascular physiology and cocaine-induced conditioned place preference (CPP) in longitudinal adults. Larval fish showed a progressive decrease in telencephalic size with increased doses of cocaine. These treated larvae also showed a dose dependent response in heart rate that persisted 24 h after drug cessation. Embryonic cocaine exposure had little effect on overall health of longitudinal adults, but subtle changes in cardiovascular physiology were seen including decreased sensitivity to isoproterenol and increased sensitivity to cocaine. These longitudinal adult fish also showed an embryonic dose-dependent change in CPP behavior, suggesting an increased sensitivity. These studies clearly show that pre-exposure during embryonic development affects subsequent cocaine sensitivity in longitudinal adults. PMID:27258254

  3. Cardiovascular Risk Behavior among Sedentary Female Smokers and Smoking Cessation Outcomes

    Directory of Open Access Journals (Sweden)

    Terwal Donna

    2005-12-01

    Full Text Available Abstract Background We examined female sedentary smokers' additional cardiovascular disease (CVD risk behaviors and their associations to smoking cessation. Methods This study was part of a randomized controlled trial testing the effectiveness of exercise and nicotine gum in smoking cessation. Included in the analyses were 148 participants. Dietary habits and alcohol consumption were measured as additional CVD risk behaviors. High-fat diet and heavy alcohol use were considered those risk behaviors. Nicotine dependence, length of the longest quit attempt, depressive symptoms, self-efficacy, and education were examined as other baseline variables. Abstinence from tobacco was recorded through 12 months. Results Diet was related to depressive symptoms at baseline. Alcohol use was related to nicotine dependence and education level. Heavy alcohol use alone and accumulation of two added risk behaviors predicted poorer smoking cessation outcome. Although diet alone was not associated with cessation outcome the high-fat diet interacted with depressive symptoms, such that the depressed women with high-fat diet were significantly more likely to relapse in their quit attempt compared to other subgroups. Conclusion Non-moderate alcohol use alone and accumulation of multiple CVD risk behaviors seem to be associated with lower success in smoking cessation.

  4. Cardiovascular Risk Behavior among Sedentary Female Smokers and Smoking Cessation Outcomes

    Directory of Open Access Journals (Sweden)

    Quiles Zandra

    2005-01-01

    Full Text Available Abstract Background We examined female sedentary smokers' additional cardiovascular disease (CVD risk behaviors and their associations to smoking cessation. Methods This study was part of a randomized controlled trial testing the effectiveness of exercise and nicotine gum in smoking cessation. Included in the analyses were 148 participants. Dietary habits and alcohol consumption were measured as additional CVD risk behaviors. High-fat diet and heavy alcohol use were considered those risk behaviors. Nicotine dependence, length of the longest quit attempt, depressive symptoms, self-efficacy, and education were examined as other baseline variables. Abstinence from tobacco was recorded through 12 months. Results Diet was related to depressive symptoms at baseline. Alcohol use was related to nicotine dependence and education level. Heavy alcohol use alone and accumulation of two added risk behaviors predicted poorer smoking cessation outcome. Although diet alone was not associated with cessation outcome the high-fat diet interacted with depressive symptoms, such that the depressed women with high-fat diet were significantly more likely to relapse in their quit attempt compared to other subgroups. Conclusion Non-moderate alcohol use alone and accumulation of multiple CVD risk behaviors seem to be associated with lower success in smoking cessation.

  5. How Does Organizational Identification Form? A Consumer Behavior Perspective

    OpenAIRE

    Melea Press; Eric J. Arnould

    2011-01-01

    This article takes a consumer behavior perspective to investigate how constituents come to identify with organizations. Using longitudinal and cross-sectional interview data collected in two contexts (one consumer and one employee), the data illustrate that constituents engage with two conduits, one formal and one informal. These conduits provide opportunities for sensegiving, which features normative elements particular to an organization, and sensemaking, an integrative process in which pro...

  6. Abortion in America: A Consumer-Behavior Perspective.

    OpenAIRE

    Patterson, Maggie Jones; Hill, Ronald Paul; Maloy, Kate

    1995-01-01

    Abortion is the most frequently performed surgical procedure in this country, yet its provision to consumers remains one of the most contentious issues within our society. The purpose of this article is to broaden our understanding of this problem by examining abortion from a consumer-behavior perspective. The phenomenological study described in this article revealed that (1) a wide gap exists between the language of the public debate and that of private decision making, (2) the language of p...

  7. Auditor Choice in the Belgian Nonprofit Sector: a Behavioral Perspective

    OpenAIRE

    REHEUL, Anne-Mie; Van Caneghem, Tom; Verbruggen, Sandra

    2011-01-01

    This study investigates auditor choice in Belgian nonprofit organizations from a behavioral perspective. We investigate whether auditor choice in favor of an auditor with a high (versus low) level of sector specialization is associated with the importance that nonprofit organizations attach to six auditor attributes: competence/integrity/deontology, working relationship with management, audit fee, practical execution of the audit, client oriented analysis and suggestions, and sector expertise...

  8. Corporate capital budgeting: Success factors from a behavioral perspective

    OpenAIRE

    Schönbohm, Avo; Zahn, Anastasia

    2012-01-01

    Capital budgeting or investment decisions have an essential influence on companies’ performance. Instead of a rational choice, capital budgeting might be regarded as a process of reality construction. Research suggests that decision makers have only limited control over their own cognitive biases in this construction process. It is in this perspective that this paper intends to answer the following research question: What are behavioral determinants for a successful capital-budgeting decision...

  9. Understanding antigay bias from a cognitive-affective-behavioral perspective.

    Science.gov (United States)

    Callender, Kevin A

    2015-01-01

    In general, United States citizens have become increasingly more accepting of lesbians and gay men over the past few decades. Despite this shift in public attitudes, antigay bias remains openly tolerated, accepted, practiced, and even defended by a substantial portion of the population. This article reviews why and how antigay bias persists using a cognitive-affective-behavioral perspective that touches on sociocognitive factors such as prejudice and stereotyping, as well as features unique to antigay bias, such as its concealable nature. The article concludes with a discussion of how understanding modern antigay bias through a cognitive-affective-behavioral lens can be applied to reduce discrimination against gays and lesbians. PMID:25530128

  10. Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study

    DEFF Research Database (Denmark)

    Kaur-Knudsen, Diljit; Bojesen, Stig E; Tybjærg-Hansen, Anne; Nordestgaard, Børge G

    2011-01-01

    We examined the associations between the nicotinic acetylcholine receptor polymorphism (rs1051730) on chromosome 15q25 marking the gene cluster CHRNA3-CHRNB4-CHRNA5, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases in the general population.......We examined the associations between the nicotinic acetylcholine receptor polymorphism (rs1051730) on chromosome 15q25 marking the gene cluster CHRNA3-CHRNB4-CHRNA5, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases in the general population....

  11. Efficacy of dietary behavior modification for preserving cardiovascular health and longevity.

    Science.gov (United States)

    Pryde, Moira McAllister; Kannel, William Bernard

    2010-01-01

    Cardiovascular disease (CVD) and its predisposing risk factors are major lifestyle and behavioral determinants of longevity. Dietary lifestyle choices such as a heart healthy diet, regular exercise, a lean weight, moderate alcohol consumption, and smoking cessation have been shown to substantially reduce CVD and increase longevity. Recent research has shown that men and women who adhere to this lifestyle can substantially reduce their risk of coronary heart disease (CHD). The preventive benefits of maintaining a healthy lifestyle exceed those reported for using medication and procedures. Among the modifiable preventive measures, diet is of paramount importance, and recent data suggest some misconceptions and uncertainties that require reconsideration. These include commonly accepted recommendations about polyunsaturated fat intake, processed meat consumption, fish choices and preparation, transfatty acids, low carbohydrate diets, egg consumption, coffee, added sugar, soft drink beverages, glycemic load, chocolate, orange juice, nut consumption, vitamin D supplements, food portion size, and alcohol. PMID:21253499

  12. Efficacy of Dietary Behavior Modification for Preserving Cardiovascular Health and Longevity

    Directory of Open Access Journals (Sweden)

    Moira McAllister Pryde

    2011-01-01

    Full Text Available Cardiovascular disease (CVD and its predisposing risk factors are major lifestyle and behavioral determinants of longevity. Dietary lifestyle choices such as a heart healthy diet, regular exercise, a lean weight, moderate alcohol consumption, and smoking cessation have been shown to substantially reduce CVD and increase longevity. Recent research has shown that men and women who adhere to this lifestyle can substantially reduce their risk of coronary heart disease (CHD. The preventive benefits of maintaining a healthy lifestyle exceed those reported for using medication and procedures. Among the modifiable preventive measures, diet is of paramount importance, and recent data suggest some misconceptions and uncertainties that require reconsideration. These include commonly accepted recommendations about polyunsaturated fat intake, processed meat consumption, fish choices and preparation, transfatty acids, low carbohydrate diets, egg consumption, coffee, added sugar, soft drink beverages, glycemic load, chocolate, orange juice, nut consumption, vitamin D supplements, food portion size, and alcohol.

  13. Sedentary leisure time behavior, snacking habits and cardiovascular biomarkers: the Inter99 Study

    DEFF Research Database (Denmark)

    Frydenlund, Gitte; Jørgensen, Torben; Toft, Ulla;

    2011-01-01

    Aim: To explore the association between sedentary leisure time behavior (SLTB) and cardiovascular biomarkers, taking into account snacking habits, alcohol intake and physical activity level. Design: Cross-sectional. Methods: Study participants were recruited from the 5-year follow-up of a...... population-based intervention study, The Inter99 Study (1999-2006, Copenhagen, Denmark). A group of 6536 men and women, aged 35-65, was invited to attend a health examination and fill in a self-report questionnaire. Multiple linear regression analysis was applied. Results: Response rate was 69% (N = 4511...... non-significant in men (ß = 0.9924, [0.9839; 1.0011]) and women (ß = 0.9932, [0.8605; 1.0014]). Conclusion: SLTB appears to be an independent CVD risk factor, regardless of snacking habits and physical activity....

  14. Klinefelter syndrome, cardiovascular system, and thromboembolic disease: review of literature and clinical perspectives.

    Science.gov (United States)

    Salzano, Andrea; Arcopinto, Michele; Marra, Alberto M; Bobbio, Emanuele; Esposito, Daniela; Accardo, Giacomo; Giallauria, Francesco; Bossone, Eduardo; Vigorito, Carlo; Lenzi, Andrea; Pasquali, Daniela; Isidori, Andrea M; Cittadini, Antonio

    2016-07-01

    Klinefelter syndrome (KS) is the most frequently occurring sex chromosomal aberration in males, with an incidence of about 1 in 500-700 newborns. Data acquired from large registry-based studies revealed an increase in mortality rates among KS patients when compared with mortality rates among the general population. Among all causes of death, metabolic, cardiovascular, and hemostatic complication seem to play a pivotal role. KS is associated, as are other chromosomal pathologies and genetic diseases, with cardiac congenital anomalies that contribute to the increase in mortality. The aim of the current study was to systematically review the relationships between KS and the cardiovascular system and hemostatic balance. In summary, patients with KS display an increased cardiovascular risk profile, characterized by increased prevalence of metabolic abnormalities including Diabetes mellitus (DM), dyslipidemia, and alterations in biomarkers of cardiovascular disease. KS does not, however, appear to be associated with arterial hypertension. Moreover, KS patients are characterized by subclinical abnormalities in left ventricular (LV) systolic and diastolic function and endothelial function, which, when associated with chronotropic incompetence may led to reduced cardiopulmonary performance. KS patients appear to be at a higher risk for cardiovascular disease, attributing to an increased risk of thromboembolic events with a high prevalence of recurrent venous ulcers, venous insufficiency, recurrent venous and arterial thromboembolism with higher risk of deep venous thrombosis or pulmonary embolism. It appears that cardiovascular involvement in KS is mainly due to chromosomal abnormalities rather than solely on low serum testosterone levels. On the basis of evidence acquisition and authors' own experience, a flowchart addressing the management of cardiovascular function and prognosis of KS patients has been developed for clinical use. PMID:26850445

  15. Time-perspective in cardiovascular risk of NSAID use after first-time myocardial infarction

    DEFF Research Database (Denmark)

    Olsen, Anne-Marie Schjerning; Gislason, Gunnar H; Fosbøl, Emil L

    2013-01-01

    PURPOSE OF REVIEW: Despite the fact that NSAIDs are not recommended among patients with established cardiovascular disease, many patients receive NSAID treatment for a short period of time. However, up until recently, data on the relationship between treatment duration and associated cardiovascular...... risk were sparse and have not been summarized. RECENT FINDINGS: A series of recent studies of patients with prior myocardial infarction (MI) demonstrated that short-term treatment with most NSAIDs is associated with an increased cardiovascular risk relative to no NSAID treatment. These studies...... furthermore demonstrated that NSAID use among patients with first-time MI was associated with persistently increased risk of all-cause mortality and of a composite of coronary death or nonfatal recurrent MI for at least 5 years thereafter. SUMMARY: The present review indicates that there is no apparent well...

  16. The prevalence and correlates of behavioral risk factors for cardiovascular health among Southern Brazil adolescents: a cross-sectional study

    OpenAIRE

    Barbosa Filho Valter; de Campos Wagner; Bozza Rodrigo; Lopes Adair da

    2012-01-01

    Abstract Background The adoption of health-related behaviors is an important part of adolescence. This study examined the prevalence and correlates of the isolated and simultaneous presence of behavioral risk factors for cardiovascular health (BRFCH) among adolescents in Curitiba, Southern Brazil. Methods A cross-sectional study was performed with 1,628 adolescents (aged 11-17.9 years, 52.5% males) that were randomly selected from 44 public schools. Self-report instruments were used to assess...

  17. Modifying health behavior to prevent cardiovascular diseases: a nationwide survey among German primary care physicians.

    Science.gov (United States)

    Schneider, Sven; Diehl, Katharina; Bock, Christina; Herr, Raphael M; Mayer, Manfred; Görig, Tatiana

    2014-04-01

    Cardiovascular diseases (CVD) are a major public health concern as they are the leading cause of death in developed countries. Primary care is considered to be the ideal setting for CVD prevention. Therefore, more than 4,000 German primary care physicians (PCPs) were asked about their attitudes towards and their activities regarding the prevention of CVD in the nationwide ÄSP-kardio Study. The focus of the study was on health behavior modification. Two thirds of the participating PCPs stated that they routinely provided brief inventions to assist patients in reducing both their tobacco (72%) and alcohol (61%) consumption, to encourage them to increase their levels of physical activity (72%), and to assist them in adjusting to a more healthy diet (66%), and in achieving a healthy body weight (69%). However, only between 23% (quitting smoking) and 49% (diet modification) of PCPs felt that they had been successful in helping patients modify their lifestyles. Insufficient reimbursement, cultural diversity and a lack of time were reported to be the most problematic barriers to successful intervention in the primary care setting. Despite these obstacles, the majority of German PCPs was engaged in prevention and health behavior intervention to reduce the incidence and progression of CVD. PMID:24739770

  18. Modifying Health Behavior to Prevent Cardiovascular Diseases: A Nationwide Survey among German Primary Care Physicians

    Directory of Open Access Journals (Sweden)

    Sven Schneider

    2014-04-01

    Full Text Available Cardiovascular diseases (CVD are a major public health concern as they are the leading cause of death in developed countries. Primary care is considered to be the ideal setting for CVD prevention. Therefore, more than 4,000 German primary care physicians (PCPs were asked about their attitudes towards and their activities regarding the prevention of CVD in the nationwide ÄSP-kardio Study. The focus of the study was on health behavior modification. Two thirds of the participating PCPs stated that they routinely provided brief inventions to assist patients in reducing both their tobacco (72% and alcohol (61% consumption, to encourage them to increase their levels of physical activity (72%, and to assist them in adjusting to a more healthy diet (66%, and in achieving a healthy body weight (69%. However, only between 23% (quitting smoking and 49% (diet modification of PCPs felt that they had been successful in helping patients modify their lifestyles. Insufficient reimbursement, cultural diversity and a lack of time were reported to be the most problematic barriers to successful intervention in the primary care setting. Despite these obstacles, the majority of German PCPs was engaged in prevention and health behavior intervention to reduce the incidence and progression of CVD.

  19. Physical fittness and cardiovascular risk factors in children : an epidemiological perspective

    NARCIS (Netherlands)

    S.A. de Man (Stella)

    1991-01-01

    textabstractThe studies on physical fitness in children as descnbed in this thesis address the following questions: (1) is there a relation between physical fitness and cardiovascular risk factors, notably blood pressure and serum lipids and lipoproteins, at a young age? (2) what is the effect of in

  20. Factors Affecting Indigenous West Australians' Health Behavior: Indigenous Perspectives.

    Science.gov (United States)

    Waterworth, Pippa; Dimmock, James; Pescud, Melanie; Braham, Rebecca; Rosenberg, Michael

    2016-01-01

    The factors driving the disparity in health outcomes between Indigenous and non-Indigenous Australians include socio-economic factors, racism, and history. The current study focused on exploring Indigenous participants' perspectives of the factors that affect the health behavior of their community members. Participatory action research methodology and a grounded theory approach were utilized. In total, 120 members of two urban West Australian Indigenous communities participated in focus group discussions. There was substantial similarity between the themes that emerged within the discussions held in the two communities. Factors relating to culture, social connections, racism, communication, and personal aspects were particularly salient to health behavior of the participants. Several of the themes including culture, racism, communication, and distrust highlight the tension caused by being a member of a minority cultural group that has been marginalized by the practices and attitudes of the dominant cultural group. Personal choice was sometimes prioritized over health. PMID:25847855

  1. Dietary behaviors of adults born prematurely may explain future risk for cardiovascular disease.

    Science.gov (United States)

    Sharafi, Mastaneh; Duffy, Valerie B; Miller, Robin J; Winchester, Suzy B; Huedo-Medina, Tania B; Sullivan, Mary C

    2016-04-01

    Being born prematurely associates with greater cardiovascular disease (CVD) risk in adulthood. Less understood are the unique and joint associations of dietary patterns and behaviors to this elevated risk among adults who are born prematurely. We aimed to model the associations between term status, dietary and lifestyle behaviors with CVD risk factors while accounting for the longitudinal effects of family protection, and medical or environmental risks. In wave-VIII of a longitudinal study, 23-year olds born prematurely (PT-adults, n = 129) and full term (FT-adults, n = 38) survey-reported liking for foods/beverages and activities, constructed into indexes of dietary quality and sensation-seeking, dietary restraint and physical activity. Measured CVD risk factors included fasting serum lipids and glucose, blood pressure and adiposity. In bivariate relationships, PT-adults reported lower dietary quality (including less affinity for protein-rich foods and higher affinity for sweets), less liking for sensation-seeking foods/activities, and less restrained eating than did FT-adults. In comparison to nationally-representative values and the FT-adults, PT-adults showed greater level of CVD risk factors for blood pressure and serum lipids. In structural equation modeling, dietary quality completely mediated the association between term status and HDL-cholesterol (higher quality, lower HDL-cholesterol) yet joined term status to explain variability in systolic blood pressure (PT-adults with lowest dietary quality had highest blood pressures). Through lower dietary quality, being born prematurely was indirectly linked to higher cholesterol/HDL, higher LDL/HDL and elevated waist/hip ratios. The relationship between dietary quality and CVD risk was strongest for PT-adults who had developed greater cumulative medical risk. Protective environments failed to attenuate relationships between dietary quality and elevated CVD risk among PT-adults. In summary, less healthy dietary

  2. Mitochondria-targeted agents: Future perspectives of mitochondrial pharmaceutics in cardiovascular diseases

    OpenAIRE

    Ajith, Thekkuttuparambil Ananthanarayanan; Jayakumar, Thankamani Gopinathan

    2014-01-01

    Mitochondria are one of the major sites for the generation of reactive oxygen species (ROS) as an undesirable side product of oxidative energy metabolism. Damaged mitochondria can augment the generation of ROS. Dysfunction of mitochondria increase the risk for a large number of human diseases, including cardiovascular diseases (CVDs). Heart failure (HF) following ischemic heart disease, infantile cardiomyopathy and cardiac hypertrophy associated with left ventricular dilations are some of the...

  3. Effects of acupuncture on behavioral, cardiovascular and hormonal responses in restraint-stressed Wistar rats

    Directory of Open Access Journals (Sweden)

    Guimarães C.M.

    1997-01-01

    Full Text Available Stress is a well-known entity and may be defined as a threat to the homeostasis of a being. In the present study, we evaluated the effects of acupuncture on the physiological responses induced by restraint stress. Acupuncture is an ancient therapeutic technique which is used in the treatment and prevention of diseases. Its proposed mechanisms of action are based on the principle of homeostasis. Adult male Wistar EPM-1 rats were divided into four groups: group I (N = 12, unrestrained rats with cannulas previously implanted into their femoral arteries for blood pressure and heart rate measurements; group II (N = 12, rats that were also cannulated and were submitted to 60-min immobilization; group III (N = 12, same as group II but with acupuncture needles implanted at points SP6, S36, REN17, P6 and DU20 during the immobilization period; group IV (N = 14, same as group III but with needles implanted at points not related to acupuncture (non-acupoints. During the 60-min immobilization period animals were assessed for stress-related behaviors, heart rate, blood pressure and plasma corticosterone, noradrenaline and adrenaline levels. Group III animals showed a significant reduction (60% on average, P<0.02 in restraint-induced behaviors when compared to groups II and IV. Data from cardiovascular and hormonal assessments indicated no differences between group III and group II and IV animals, but tended to be lower (50% reduction on average in group I animals. We hypothesize that acupuncture at points SP6, S36, REN17, P6 and DU20 has an anxiolytic effect on restraint-induced stress that is not due to a sedative action

  4. The grapefruit: an old wine in a new glass? Metabolic and cardiovascular perspectives.

    Science.gov (United States)

    Owira, P M; Ojewole, J A

    2010-01-01

    Grapefruit is a popular, tasty and nutritive fruit enjoyed globally. Biomedical evidence in the last 10 years has, however, shown that consumption of grapefruit or its juice is associated with drug interactions, which, in some cases, have been fatal. Grapefruit-induced drug interactions are unique in that the cytochrome P450 enzyme CYP3A4, which metabolises over 60% of commonly prescribed drugs as well as other drug transporter proteins such as P-glycoprotein and organic cation transporter proteins, which are all expressed in the intestines, are involved. However, the extent to which grapefruit-drug interactions impact on clinical settings has not been fully determined, probably because many cases are not reported. It has recently emerged that grapefruit, by virtue of its rich flavonoid content, is beneficial in the management of degenerative diseases such as diabetes and cardiovascular disorders. This potentially explosive subject is reviewed here. PMID:20972517

  5. Is that the answer you had in mind? The effect of perspective on unethical behavior

    Directory of Open Access Journals (Sweden)

    Amos Schurr

    2012-11-01

    Full Text Available We explored how the perspective through which individuals view their actions influences their ethicality, comparing a narrow perspective that allows for evaluation of each choice in isolation, to a broad perspective that promotes an aggregate view of one's choices. To examine unethical behavior we employed a computerized variation of a trivia game that challenges the player's integrity because, rather than choosing the correct answer, players indicate whether the correct highlighted answer is the answer they had in mind. In Experiment 1 perspective was modified through the choice procedure: broad perspective evoked by an aggregate decision regarding the upcoming test items and narrow perspective evoked by a segregated decision regarding each upcoming test item. In Experiment 2 perspective was evoked through differential priming. Across both experiments, when given a monetary incentive to succeed, the adoption of a narrow perspective increased cheating, as evidenced by overall higher reported success rates.

  6. Predoctoral and postdoctoral students' perspectives about pediatric dental behavior guidance.

    Science.gov (United States)

    Bimstein, Enrique; Azari, Amir F; Riley, Joseph L

    2011-05-01

    This study compared acceptability scores of pediatric dental behavior guidance between predoctoral senior dental students and postdoctoral pediatric dentistry graduates. The scores were obtained with an anonymous survey that included twenty-five items related to behavior guidance techniques or situations, with the degree of acceptability of each being marked on a visual analog scale. Demographic data collected included year of graduation from the postdoctoral program, type of employment, being board-certified or not, gender, marital and parental status, previously receiving dental or medical treatment, and degree of unpleasantness from these treatments. Thirty-nine predoctoral and fifty-one postdoctoral surveys were compared. Analysis of variance (ANOVA) indicated that the predoctoral acceptability scores were statistically significantly higher than the postdoctoral scores for not allowing the child to speak during treatment, voice control, hand over mouth, active immobilization, and providing an exact explanation to the child. The predoctoral scores were lower than the postdoctoral scores for not using local anesthetic when the child does not want it, parent's presence in the operatory during treatment, or talking with the dentist during treatment. ANOVA of the predoctoral and postdoctoral scores combined indicated statistically significant differences between scores from male and females respondents for parent talking with the dentist during treatment; between married and not married respondents for hand over mouth, encouraging the child not to be a coward, the child being allowed to stop the treatment, and the parent being in the operatory during treatment; and between parents and not parents respondents for child not allowed to speak during the treatment, voice control, and hand over mouth. This study found that perspectives about pediatric dental behavior guidance are influenced by pre- and postdoctoral education and postgraduate experience. PMID:21546595

  7. Fatores de risco cardiovasculares em adolescentes: indicadores biológicos e comportamentais Cardiovascular risk factors in adolescents: biological and behavioral indicators

    Directory of Open Access Journals (Sweden)

    Dartagnan Pinto Guedes

    2006-06-01

    Full Text Available OBJETIVO: Oferecer informações descritivas e investigar a extensão com que os fatores de risco para doenças cardiovasculares de natureza comportamental estão associados aos fatores de risco biológicos na população jovem. MÉTODOS: Amostra de 452 adolescentes (246 moças e 206 rapazes com idades entre 15 e 18 anos, selecionados de uma escola de ensino médio da cidade de Londrina, Paraná. Fatores de risco de natureza comportamental foram analisados mediante prática insuficiente de atividade física, ingestão excessiva de gorduras e de colesterol e uso de tabaco. Como indicadores dos fatores de risco biológicos recorreu-se ao sobrepeso, aos níveis elevados de pressão arterial e concentrações não-favoráveis de lipídios-lipoproteínas plasmáticas. RESULTADOS: Por volta de 20% das moças e 16% dos rapazes apresentaram pelo menos um fator de risco biológico para o desenvolvimento de doenças cardiovasculares. O sobrepeso se associou significativamente com a ingestão excessiva de gorduras, enquanto a pressão arterial elevada se relacionou com o estilo de vida sedentário e o uso de tabaco. A excessiva ingestão de gorduras e de colesterol indicou risco aumentado de concentrações indesejáveis de lipídios-lipoproteínas plasmáticas. Adolescentes fumantes tenderam a demonstrar risco de pressão arterial e de lipídios-lipoproteínas plasmáticas alterados duas vezes maior que não-fumantes. CONCLUSÃO: Os resultados reforçam a necessidade de que intervenções direcionadas à adoção de um estilo de vida saudável, incluindo prática regular de atividade física, padrões dietéticos adequados e abstenção ao uso de tabaco, deverão ser iniciadas em idades jovens.OBJECTIVE: To provide descriptive information and investigate to what extent behavioral risk factors for cardiovascular diseases are associated with biological risk factors in the young population. METHODS: The sample included 452 adolescents (246 girls and 206 boys

  8. Older People's Perspectives on Health, Physical Activity and Nutritional Behaviors

    Directory of Open Access Journals (Sweden)

    Leila Alizadeh

    2015-12-01

    Full Text Available Background: Approaches for investigating health-promoting lifestyle generally focus on physical activ­ity and regular diet. To explore the perspectives of Iranian elders regarding health, healthy eating and physical activity (PA this study was conducted in 2012. Methods: Participants in this qualitative study were selected through purposeful sampling. Ten focus groups were conducted with 60 older adults in 3 elderly centers in Tehran. A moderator’s guideline that consisted of general and specific questions was used. Focus groups were audio recorded, transcribed verbatim and analysis was performed using conventional content analysis. Results: Participants explained their perspectives regarding health, healthy eating and PA in the follow­ing 5 categories: meaning of health was represented based on issues such as absence of pain and disor­der, complete body wellbeing, staying away from hazards, complete individual satisfaction, experiencing positive events, effective communication, faithfulness and trust in God. The healthy eating category was featured by adequate eating, age balanced diet, refraining from under or over nutrition and sensible consumption of fruits and vegetables. The PA was described - according to the level of performing outdoor activities or household tasks. Expressions about the perceived benefits and barriers of healthy eating and PA were aligned the two remaining categories. Conclusions: Participants have referred to the association between both PA and dietary practices and health. Understanding how older people define physical activity and nutritional behavior and recognition of the most important perceived benefits and barriers that might contribute to have a healthy eating or adequate PA profile could procure insight into the type of interventions that are required to promote healthy lifestyle among Iranian older adults.

  9. Heart valve health, disease, replacement, and repair: a 25-year cardiovascular pathology perspective.

    Science.gov (United States)

    Schoen, Frederick J; Gotlieb, Avrum I

    2016-01-01

    The past several decades have witnessed major advances in the understanding of the structure, function, and biology of native valves and the pathobiology and clinical management of valvular heart disease. These improvements have enabled earlier and more precise diagnosis, assessment of the proper timing of surgical and interventional procedures, improved prosthetic and biologic valve replacements and repairs, recognition of postoperative complications and their management, and the introduction of minimally invasive approaches that have enabled definitive and durable treatment for patients who were previously considered inoperable. This review summarizes the current state of our understanding of the mechanisms of heart valve health and disease arrived at through innovative research on the cell and molecular biology of valves, clinical and pathological features of the most frequent intrinsic structural diseases that affect the valves, and the status and pathological considerations in the technological advances in valvular surgery and interventions. The contributions of many cardiovascular pathologists and other scientists, engineers, and clinicians are emphasized, and potentially fruitful areas for research are highlighted. PMID:27242130

  10. Mitochondria-targeted agents: Future perspectives of mitochondrial pharmaceutics in cardiovascular diseases

    Institute of Scientific and Technical Information of China (English)

    Thekkuttuparambil; Ananthanarayanan; Ajith; Thankamani; Gopinathan; Jayakumar

    2014-01-01

    Mitochondria are one of the major sites for the genera-tion of reactive oxygen species(ROS) as an undesirable side product of oxidative energy metabolism. Damaged mitochondria can augment the generation of ROS. Dys-function of mitochondria increase the risk for a large number of human diseases, including cardiovascular diseases(CVDs). Heart failure(HF) following ischemic heart disease, infantile cardiomyopathy and cardiac hypertrophy associated with left ventricular dilations are some of the CVDs in which the role of mitochon-drial oxidative stress has been reported. Advances in mitochondrial research during the last decade focused on the preservation of its function in the myocardium, which is vital for the cellular energy production. Expe-rimental and clinical trials have been conducted using mitochondria-targeted molecules like: MnSOD mimetics, such as EUK-8, EUK-134 and MitoSOD; choline esters of glutathione and N-acetyl-L-cysteine; triphenylphospho-nium ligated vitamin E, lipoic acid, plastoquinone andmitoCoQ10; and Szeto-Schiller(SS)- peptides(SS-02 and SS-31). Although many results are inconclusive, some of the findings, especially on CoQ10, are worthwhile. This review summarizes the role of mitochondria-tar-geted delivery of agents and their consequences in the control of HF.

  11. Future perspectives of a cardiac non-neuronal acetylcholine system targeting cardiovascular diseases as an adjunctive tool for metabolic intervention.

    Science.gov (United States)

    Kakinuma, Yoshihiko

    2015-11-01

    It has been several years since the function of the non-neuronal cholinergic system was independently reported in cardiomyocytes by several research groups. Although these findings initially seemed to be negligible and insignificant, extraordinary findings about cardiomyocytes were subsequently reported in studies involving the knockdown of the non-neuronal cholinergic system. These studies provide the evidence that this system may be indispensable for maintaining principal cardiac functions. Despite the absence of an appropriate and reliable technology to detect cellular ACh in real time in cardiomyocytes, studies of this system have progressed, albeit very slowly, to gradually consolidate the significance of this system. Based on the many significant findings regarding this system, these will be critical to develop adjunctive intervention therapy against cardiovascular diseases, including peripheral artery disease and heart failure. In this study, previous studies focusing on the non-neuronal cholinergic system are reviewed along with our studies, both indicating the biologically significant roles of the cardiac non-neuronal acetylcholine system from a clinical perspective. PMID:26028150

  12. An Econometric Examination of the Behavioral Perspective Model in the Context of Norwegian Retailing

    Science.gov (United States)

    Sigurdsson, Valdimar; Kahamseh, Saeed; Gunnarsson, Didrik; Larsen, Nils Magne; Foxall, Gordon R.

    2013-01-01

    The behavioral perspective model's (BPM; Foxall, 1990) retailing literature is built on extensive empirical research and techniques that were originally refined in choice experiments in behavioral economics and behavior analysis, and then tested mostly on British consumer panel data. We test the BPM in the context of Norwegian retailing. This…

  13. Why and when workplace ostracism inhibits organizational citizenship behaviors: an organizational identification perspective

    OpenAIRE

    Wu, Chia-Huei; Liu, Jun; Kwong Kwan, Ho; Lee, Cynthia

    2016-01-01

    Why and when do employees respond to workplace ostracism by withholding their engagement in citizenship behavior? Beyond perspectives proposed in past studies, we offer a new account based on a social identity perspective and propose that workplace ostracism decreases citizenship behavior by undermining employees’ identification with the organization. We also theorize that perceived job mobility influences the extent to which employees identify with the organization when being ostracized. The...

  14. p38 MAPK mediates cardiovascular and behavioral responses induced by central IL-1β and footshock in conscious rats

    Institute of Scientific and Technical Information of China (English)

    Rui-mao ZHENG; Chang-jiang ZOU; Shi-gong ZHU

    2004-01-01

    AIM: To investigate the roles of p38 mitogen-activated protein kinase (p38 MAPK) in the cardiovascular and behavioral responses induced by intracerebral ventricular injection (icv) of interleukin- 1 β (IL- 1 β) or footshock.METHODS: We examined the effects of p38 MAPK on mean artery blood pressure (mABP), heart rate (HR), and motor activity (MA) during central administration of IL- 1 β, or footshock after icv SB203580 (a specific inhibitor of the p38 MAPK) with Cardiovascular and Behavior Telemetry System in conscious SD rats. RESULTS: (1) IL-1 β (icy) or footshock remarkably rise the mABP, and the maximal changes are (7.8± 1.8) and (12.3±3.5) mmHg,respectively, which was abrogated by the pretreatment with p38 inhibitor SB203580 intracerebroventricularly. (2)Compared with icv saline group, the motor activity was significantly decreased in SB203580 group with maximal changes (-7.6± 1.1) counts/min after footshock. CONCLUSION: p38 MAPK plays an important role in the pressor response induced by central administration of IL- 1 β or footshock and change of motor activity after footshock in conscious rats.

  15. Reconciling White-Box and Black-Box Perspectives on Behavioral Self-adaptation

    DEFF Research Database (Denmark)

    Bruni, Roberto; Corradini, Andrea; Gadducci, Fabio; Hölzl, Matthias; Lluch Lafuente, Alberto; Vandin, Andrea; Wirsing, Martin

    This paper proposes to reconcile two perspectives on behavioral adaptation commonly taken at different stages of the engineering of autonomic computing systems. Requirements engineering activities often take a black-box perspective: A system is considered to be adaptive with respect to an...... environment whenever the system is able to satisfy its goals irrespectively of the environment perturbations. Modeling and programming engineering activities often take a white-box perspective: A system is equipped with suitable adaptation mechanisms and its behavior is classified as adaptive depending on...... whether the adaptation mechanisms are enacted or not. The proposed approach reconciles black- and white-box perspectives by proposing several notions of coherence between the adaptivity as observed by the two perspectives: These notions provide useful criteria for the system developer to assess and...

  16. Job Satisfaction: I/O Psychology and Organizational Behavior Management Perspectives

    Science.gov (United States)

    Mawhinney, Thomas C.

    2011-01-01

    Perspectives on job satisfaction and its relations with job performance among members of the Industrial/Organizational Psychology (IOP) and Organizational Behavior Management (OBM) cultures are identified and compared. Comparisons include vantage points of each culture on the roles of theory and data regarding the definitions of behavior, job…

  17. Socially Situated Financial Markets: A Neo-Behavioral Perspective on Firms, Investors and Practices

    NARCIS (Netherlands)

    I. Naumovska (Ivana)

    2014-01-01

    markdownabstract__Abstract__ In this dissertation I seek to redirect the conversation on stock market evaluations from the more traditional economic and behavioral finance theories, by proposing a neo-behavioral perspective, which views financial markets as socially situated. Specifically I combine

  18. Behavioral Advantages of the First-Person Perspective Model for Imitation

    Science.gov (United States)

    Watanabe, Rui; Higuchi, Takahiro

    2016-01-01

    Visuomotor information may be better conveyed through a first-person perspective than through a third-person perspective. However, few reports have shown a clear behavioral advantage of the first-person perspective because of the confounding factor of spatial stimulus–response compatibility. Most imitation studies have utilized visuospatial imitation tasks in which participants use the same body part as that used by the model, identified by its spatial position (i.e., the response action is predefined). In such studies, visuomotor information conveyed by the model does not appear to facilitate imitative behavior. We hypothesized that the use of the first-person perspective would facilitate more efficient imitative behavior than a third-person perspective when participants are asked to choose and reproduce an action identical to that of the model rather than to select the same body part; this task requires the analysis of both visual and motor information from the model rather than a simple assessment of spatial information. To test this hypothesis, we asked 15 participants to observe a model from two perspectives (first-person and third-person) with left or right hand laterality and to lift their index finger with an identical movement type (extension or flexion) as quickly as possible. Response latencies were shorter and fewer errors were made in trials using the first-person perspective than in those using the third-person perspective, regardless of whether the model used the right or left hand. These findings suggest that visuomotor information from the first-person perspective, without confounding effects of spatial information, facilitates efficient imitative behavior. PMID:27242614

  19. Cardiovascular risk behavior among students of a Medical College in Delhi

    Directory of Open Access Journals (Sweden)

    N Rustagi

    2011-01-01

    Full Text Available Background: Life style related behavioural risk factors are mainly implicated for increased burden of cardio- vascular diseases. Research related to these risk behaviours especially among medical students is essential, considering their role as future physicians and role models in public health intervention programmes. Objective: To evaluate the burden of cardiovascular risk behaviours among students of a medical college of Delhi, India. Materials and Methods: A cross sectional study was carried out among undergraduate medical students of a medical college in Delhi. Self administered questionnaire was used to collect information on identification data and risk behaviours in relation to cardiovascular diseases. Binary logistic regression analysis was done to calculate adjusted odds ratio to assess association between risk behaviours and covariates. Results: The minimum recommendation of taking at least five servings per day of fruits and vegetables was complied only by 12% of students. Consumption of carbonated soft drinks either once or more on daily basis was present in 23.7% students and 32.0% reported frequent consumption of fast foods in past week. Consumption of alcohol was present in 28.8% students but only small proportion of students (7% was current tobacco users. Large proportions of students (42.6% were either not carrying out or were involved in only occasional physical activity in past week. Conclusions: Unhealthy behavioural practises are present and may progress as student advance through medical college. Developing strategies targeting at these risk behaviours and determining factors is necessary to promote healthy life style among medical students.

  20. A Historical Perspective on the Future of Behavior Science.

    Science.gov (United States)

    Hayes, Linda J; Fryling, Mitch J

    2015-10-01

    Like all natural sciences, behavior science has much to offer toward an understanding of the world. The extent to which the promise of behavior science is realized, though, depends upon the extent to which we keep what we know before us. This paper considers fundamental concepts in behavior science, including the concepts of behavior, stimulation, setting conditions, and language. In considering these concepts, we revisit comments from B. F. Skinner and J. R. Kantor and also consider some areas of behavior analytic research and the implications they have for reconsidering long-held assumptions about the analysis of behavior. We hope that, in considering our foundations, the vitality and strength of the discipline might be enhanced, our impact on science improved, and our future secured. PMID:27606169

  1. Effects of Nutrition and Exercise Health Behaviors on Predicted Risk of Cardiovascular Disease among Workers with Different Body Mass Index Levels

    OpenAIRE

    Jui-Hua Huang; Shu-Ling Huang; Ren-Hau Li; Ling-Hui Wang; Yu-Ling Chen; Feng-Cheng Tang

    2014-01-01

    Workplace health promotion programs should be tailored according to individual needs and efficient intervention. This study aimed to determine the effects of nutrition and exercise health behaviors on predicted risk for cardiovascular disease (CVD) when body mass index (BMI) is considered. In total, 3350 Taiwanese workers were included in this cross-sectional study. A self-reported questionnaire was used to measure their nutrition and exercise behaviors. Data on anthropometric values, biochem...

  2. Perspectives on communicating health food behavior in health blogs

    OpenAIRE

    Ahokas, Hannele

    2015-01-01

    The purpose of this research was to gain a better understanding of the meanings consumers attach to health food consumption. The phenomena was observed from the perspective of health food bloggers and in addition to how the bloggers communicated their health food behaviour, the role of word-of-mouth in electronic environment and companies’ word-of-mouth marketing was also investigated. The research was carried out using qualitative research methods and the empirical part of the stud...

  3. "Correlates of Affectionate and Angry Behavior." Practitioner Perspective.

    Science.gov (United States)

    Moberly, Deborah

    1999-01-01

    Notes that the most comforting finding in Mill and Romano- White's study was the high level of affectionate caregiver behaviors in early childhood settings. Suggests that a broader definition of anger might yield different results. Argues that the lack of a relationship between caregivers' self-esteem and angry or affectionate behavior contradicts…

  4. Examination of the Obesity Epidemic from a Behavioral Perspective

    Science.gov (United States)

    Shields, A. Tamlyn

    2009-01-01

    Obesity prevalence has doubled among adults and overweight has tripled among children since 1980. This article discusses behavioral approaches to the obesity epidemic, focusing on recent environmental changes, the resulting behaviors, and possible solutions. Over the last 4 decades, time spent in sedentary activities, the consumption of fast food,…

  5. Experiences and perceptions about cause and prevention of cardiovascular disease among people with cardiometabolic conditions: findings of in-depth interviews from a peri-urban Nepalese community

    OpenAIRE

    Oli, Natalia; Vaidya, Abhinav; Subedi, Madhusudan; Krettek, Alexandra

    2014-01-01

    Background: Nepal currently faces an increasing burden of cardiovascular disease (CVD). Earlier studies on health literacy and the behavior dimension of cardiovascular health reported a substantial gap between knowledge and practice.Objective: This qualitative study aimed to deepen understanding of the community perspective on cardiovascular health from the patients’ viewpoint.Design: We conducted in-depth interviews (IDIs) with 13 individuals with confirmed heart disease, hypertension, or di...

  6. Caregiver perspectives of memory and behavior changes in stroke survivors.

    Science.gov (United States)

    Clark, Patricia C; Dunbar, Sandra B; Aycock, Dawn M; Courtney, Elizabeth; Wolf, Steven L

    2006-01-01

    Post-stroke memory and behavior changes (MBC) are associated with negative outcomes for stroke survivors and caregivers. This article describes the types of MBC that occur most frequently and caregivers' responses to these behaviors. Data were obtained through in-person interviews and administration of questionnaires to 132 caregivers of first-time stroke survivors 3-9 months after stroke. MBC were measured with a modified version of a Memory and Behavior Problems checklist. On average, caregivers reported 7.7 +/- 3.6 (range 0-17) behaviors. Common stroke survivor MBC included appearing sad or depressed, interrupting the caregiver, and being restless or agitated. These MBC were distressing to caregivers. Caregivers may not recognize some MBC as potential symptoms of depression. In addition, caregiver misunderstanding of the amount of control survivors may have over some behaviors has implications for rehabilitation and caregivers' responses to these changes. PMID:16422042

  7. An overview of cardiovascular risk factor burden in sub-Saharan African countries: a socio-cultural perspective

    Directory of Open Access Journals (Sweden)

    Degboe Arnold N

    2009-09-01

    Full Text Available Abstract Background Sub-Saharan African (SSA countries are currently experiencing one of the most rapid epidemiological transitions characterized by increasing urbanization and changing lifestyle factors. This has resulted in an increase in the incidence of non-communicable diseases, especially cardiovascular disease (CVD. This double burden of communicable and chronic non-communicable diseases has long-term public health impact as it undermines healthcare systems. Purpose The purpose of this paper is to explore the socio-cultural context of CVD risk prevention and treatment in sub-Saharan Africa. We discuss risk factors specific to the SSA context, including poverty, urbanization, developing healthcare systems, traditional healing, lifestyle and socio-cultural factors. Methodology We conducted a search on African Journals On-Line, Medline, PubMed, and PsycINFO databases using combinations of the key country/geographic terms, disease and risk factor specific terms such as "diabetes and Congo" and "hypertension and Nigeria". Research articles on clinical trials were excluded from this overview. Contrarily, articles that reported prevalence and incidence data on CVD risk and/or articles that report on CVD risk-related beliefs and behaviors were included. Both qualitative and quantitative articles were included. Results The epidemic of CVD in SSA is driven by multiple factors working collectively. Lifestyle factors such as diet, exercise and smoking contribute to the increasing rates of CVD in SSA. Some lifestyle factors are considered gendered in that some are salient for women and others for men. For instance, obesity is a predominant risk factor for women compared to men, but smoking still remains mostly a risk factor for men. Additionally, structural and system level issues such as lack of infrastructure for healthcare, urbanization, poverty and lack of government programs also drive this epidemic and hampers proper prevention, surveillance and

  8. Why and when workplace ostracism inhibits organizational citizenship behaviors: An organizational identification perspective.

    Science.gov (United States)

    Wu, Chia-Huei; Liu, Jun; Kwan, Ho Kwong; Lee, Cynthia

    2016-03-01

    Why and when do employees respond to workplace ostracism by withholding their engagement in citizenship behavior? Beyond perspectives proposed in past studies, we offer a new account based on a social identity perspective and propose that workplace ostracism decreases citizenship behavior by undermining employees' identification with the organization. We also theorize that perceived job mobility influences the extent to which employees identify with the organization when being ostracized. These hypotheses were examined in two time-lagged studies conducted in China. The proposed hypotheses were supported by results in Study 1, and findings were generally replicated in Study 2, where effects of other known mediators (i.e., organization-based self-esteem, job engagement, and felt obligation toward the organization) and moderators (i.e., collectivism, power distance, and future orientation) suggested by previous perspectives were controlled. Results of Study 2 provided further support of the hypothesized directional effect of workplace ostracism on citizenship behavior via organizational identification. Our studies support the identification perspective in understanding workplace ostracism and also strengthen the application of this perspective in understanding workplace aggression broadly. PMID:26524112

  9. Social behavior in the “Age of Empathy”?:A social scientist's perspective on current trends in the behavioral sciences

    OpenAIRE

    Matusall, Svenja

    2013-01-01

    Recently, several behavioral sciences became increasingly interested in investigating biological and evolutionary foundations of (human) social behavior. In this light, prosocial behavior is seen as a core element of human nature. A central role within this perspective plays the “social brain” that is not only able to communicate with the environment but rather to interact directly with other brains via neuronal mind reading capacities such as empathy. From the perspective of a sociologist, t...

  10. Corporate Governance and Ethical Behavior: A National Perspective

    OpenAIRE

    Ionel-Alin Ienciu

    2012-01-01

    Ethical behavior is an important aspect for the success of a company, as it influences its relations with various stakeholders. Our study reflects how the efficiency of the board of directors influences the ethical behavior of companies. We conclude stating that the efficiency of the board of directors, ensured by a sufficient number of members, by the predominance of independent non-executive members would lead to an efficient supervision of the executives, impeding the management from actin...

  11. A psychological contract perspective on organizational citizenship behavior

    OpenAIRE

    Coyle-Shapiro, Jacqueline A.

    2002-01-01

    This study examined the contribution of the psychological contract framework to understanding organizational citizenship behavior (OCB) using survey data gathered at three measurement points over a three year period from 480 public sector employees. Separating perceived contract breach into its two components, the data suggest that perceived employer obligations explained unique variance in three dimensions of citizenship behavior (helping, advocacy and functional participation) beyond that a...

  12. Behavioral Perspectives on the Neuroscience of Drug Addiction

    OpenAIRE

    Winger, Gail; Woods, James H; Galuska, Chad M; Wade-Galuska, Tammy

    2005-01-01

    Neuroscientific approaches to drug addiction traditionally have been based on the premise that addiction is a process that results from brain changes that in turn result from chronic administration of drugs of abuse. An alternative approach views drug addiction as a behavioral disorder in which drugs function as preeminent reinforcers. Although there is a fundamental discrepancy between these two approaches, the emerging neuroscience of reinforcement and choice behavior eventually may shed li...

  13. Unihemispheric sleep and asymmetrical sleep: behavioral, neurophysiological, and functional perspectives

    OpenAIRE

    Mascetti GG

    2016-01-01

    Gian Gastone Mascetti Department of General Psychology, University of Padova, Padova, Italy Abstract: Sleep is a behavior characterized by a typical body posture, both eyes' closure, raised sensory threshold, distinctive electrographic signs, and a marked decrease of motor activity. In addition, sleep is a periodically necessary behavior and therefore, in the majority of animals, it involves the whole brain and body. However, certain marine mammals and species of birds show a different s...

  14. The Concept of Employee Engagement: A Comprehensive Review from a Positive Organizational Behavior Perspective

    Science.gov (United States)

    Jeung, Chang-Wook

    2011-01-01

    Employee engagement has been understood from various academic and practical perspectives, mainly due to its recent popularity. This study explores not only positive movements--positive psychology, positive organizational scholarship (POS), and positive organizational behavior (POB)--as a background of engagement but also the conceptualization,…

  15. Future Time Perspective as a Predictor of Adolescents' Adaptive Behavior in School

    Science.gov (United States)

    Carvalho, Renato Gil Gomes

    2015-01-01

    Future time perspective (FTP) has been associated with positive outcomes in adolescents' development across different contexts. However, the extent to which FTP influences adaptation needs additional understanding. In this study, we analysed the relationship between FTP and adolescents' behavior in school, as expressed in several indicators of…

  16. Binge-Eating Disorder: Between Eating Disorders and Obesity? A Cognitive-Behavioral Perspective

    OpenAIRE

    Juanita Gempeler Rueda

    2005-01-01

    Abstract This article reviews the available literature on binge-eating disorder, currently included in the DSM IV as an Eating Disorder NOS. Its inclusion in the DSM V is under discussion. Conceptualization of this disorder is examined, as well as implications for clinical interventions from a cognitive-behavioral perspective.

  17. British Philosopher Gilbert Ryle’s Perspective on Behaviorism

    Directory of Open Access Journals (Sweden)

    Elena BANCIU

    2012-12-01

    Full Text Available Published in 1890, William James’ manual, The principles of psychology, followed by Psychology (lectures in 1892, form the foundation of behaviorism. The same year, Animal life and intelligence by C. Lloyd Morgan correlates with James’ view, extending it to wildlife. The next step was taken by Lloyd Morgan, with the publication of An introduction to comparative psychology (1894, in which the issue of trial and error learning in animals receives a systematic approach, thus pointing research to a specific area and interpretive apparatus that will ultimately lead to the full crystallization of behaviorism’s ideas in the past century. The most prestigious version of behaviorism, that of psychological behaviorism, has strong historical roots; in this way, one can invoke the works of Aristotle (On Nature. Another version of behaviorism, like that suggested by Gilbert Ryle, is logical behaviorism. Long before that, however, classical British empiricists, led by John Locke (1632-1704 and David Hume (1711-1776, used associationist prescriptions to reveal cause-effect coupling in mental phenomena.

  18. Psychological perspective for a theory of behavior during riots.

    Science.gov (United States)

    Lachman, S J

    1996-12-01

    In a riot situation some individuals actively participate in antisocial behavior, but others do not, and still others act to discourage hostile activity. Four concepts from general psychology including (1) insufficiency of internal control or lack of internalized restraints acquired through learning, (2) effects of frustration, (3) emotional excitement, and (4) precipitating incidents (one or more) are proposed as contributors to the behavioral involvement of participants. Some hypotheses and the role of such variables as emotional contagion, imitation, opportunism, and anonymity are discussed. PMID:8969079

  19. Managing sedentary behavior to reduce the risk of diabetes and cardiovascular disease.

    Science.gov (United States)

    Dempsey, Paddy C; Owen, Neville; Biddle, Stuart J H; Dunstan, David W

    2014-01-01

    Modern human environments are vastly different from those of our forebears. Rapidly advancing technology in transportation, communications, workplaces, and home entertainment confer a wealth of benefits, but increasingly come with costs to human health. Sedentary behavior-too much sitting as distinct from too little physical activity-contributes adversely to cardiometabolic health outcomes and premature mortality. Findings from observational epidemiology have been synthesized in meta-analyses, and evidence is now shifting into the realm of experimental trials with the aim of identifying novel mechanisms and potential causal relationships. We discuss recent observational and experimental evidence that makes a compelling case for reducing and breaking up prolonged sitting time in both the primary prevention and disease management contexts. We also highlight future research needs, the opportunities for developing targeted interventions, and the potential of population-wide initiatives designed to address too much sitting as a health risk. PMID:25052856

  20. Emissions trading for households? : A behavioral law and economics perspective

    NARCIS (Netherlands)

    Woerdman, Edwin; Bolderdijk, Jan

    2016-01-01

    This is the first research article on expanding emissions trading in the EU to households in which law and economics is explicitly and systematically combined with behavioral science. The goal of the article is neither to plead in favor nor against emissions trading for households, but rather to pro

  1. Youth at Risk and the Family: Perspectives on Behavior.

    Science.gov (United States)

    Nelson, Douglas C.; Oles, Gordon

    1993-01-01

    This literature review addresses determinants of low behavior control in parenting adolescents at risk. The Barber and Belsky models are used to discuss parent developmental history, parent maturity, parent mental health, socioeconomic status, sources of stress (parent involvement, marital conflict, and job satisfaction), and child…

  2. A developmental behavior-genetic perspective on alcoholism risk.

    Science.gov (United States)

    Rose, R J

    1998-01-01

    Although behavioral problems associated with abuse of alcohol emerge during late adolescence and adulthood, some behavioral characteristics indicative of an increased risk of alcoholism may already be obvious during early childhood. Studies in several countries have demonstrated that children with high levels of novelty-seeking behavior and low levels of harm-avoidance behavior are more likely to develop alcohol-related problems during adolescence. Moreover, as early as age 3, children at high risk of future alcoholism because of a family history are more active, more impatient, and more aggressive than matched controls of low-risk children. Causal influences on the initiation of drinking must be distinguished from those that affect patterns of consumption once drinking is initiated. Studies of adolescent twins have demonstrated that initiation of drinking is primarily influenced by the drinking status of parents, siblings, and friends and by socioregional differences in the environments within which adolescent twins reside. The influence of genetic factors is negligible. Conversely, once initiated, differences in frequency and quantity of drinking are strongly influenced by genetic factors. However, these influences, too, are modulated by sibling and peer effects and by regional environmental variation. PMID:15706788

  3. A sociogenomic perspective on neuroscience in organizational behavior

    Directory of Open Access Journals (Sweden)

    Seth Michael Spain

    2014-02-01

    Full Text Available We critically examine the current biological models of individual organizational behavior, with particular emphasis on the roles of genetics and the brain. We demonstrate how approaches to biology in the organizational sciences assume that biological systems are simultaneously causal and essentially static; that genotypes exert constant effects. In contrast, we present a sociogenomic approach to organizational research, which could provide a meta-theoretical framework for understanding organizational behavior. Sociogenomics is an interactionist approach that derives power from its ability to explain how genes and environment operate. The key insight is that both genes and the environment operate by modifying gene expression. This leads to a conception of genetic and environmental effects that is fundamentally dynamic, rather than the static view of classical biometric approaches. We review biometric research within organizational behavior, and contrast these interpretations with a sociogenomic view. We provide a review of gene expression mechanisms that help explain the dynamism observed in individual organizational behavior, particularly factors associated with gene expression in the brain. Finally, we discuss the ethics of genomic and neuroscientific findings for practicing managers and discuss whether it is possible to practically apply these findings in management.

  4. Behavioral Perspectives on the Neuroscience of Drug Addiction

    Science.gov (United States)

    Winger, Gail; Woods, James H.; Galuska, Chad M.; Wade-Galuska, Tammy

    2005-01-01

    Neuroscientific approaches to drug addiction traditionally have been based on the premise that addiction is a process that results from brain changes that in turn result from chronic administration of drugs of abuse. An alternative approach views drug addiction as a behavioral disorder in which drugs function as preeminent reinforcers. Although…

  5. Unihemispheric sleep and asymmetrical sleep: behavioral, neurophysiological, and functional perspectives.

    Science.gov (United States)

    Mascetti, Gian Gastone

    2016-01-01

    Sleep is a behavior characterized by a typical body posture, both eyes' closure, raised sensory threshold, distinctive electrographic signs, and a marked decrease of motor activity. In addition, sleep is a periodically necessary behavior and therefore, in the majority of animals, it involves the whole brain and body. However, certain marine mammals and species of birds show a different sleep behavior, in which one cerebral hemisphere sleeps while the other is awake. In dolphins, eared seals, and manatees, unihemispheric sleep allows them to have the benefits of sleep, breathing, thermoregulation, and vigilance. In birds, antipredation vigilance is the main function of unihemispheric sleep, but in domestic chicks, it is also associated with brain lateralization or dominance in the control of behavior. Compared to bihemispheric sleep, unihemispheric sleep would mean a reduction of the time spent sleeping and of the associated recovery processes. However, the behavior and health of aquatic mammals and birds does not seem at all impaired by the reduction of sleep. The neural mechanisms of unihemispheric sleep are unknown, but assuming that the neural structures involved in sleep in cetaceans, seals, and birds are similar to those of terrestrial mammals, it is suggested that they involve the interaction of structures of the hypothalamus, basal forebrain, and brain stem. The neural mechanisms promoting wakefulness dominate one side of the brain, while those promoting sleep predominates the other side. For cetaceans, unihemispheric sleep is the only way to sleep, while in seals and birds, unihemispheric sleep events are intermingled with bihemispheric and rapid eye movement sleep events. Electroencephalogram hemispheric asymmetries are also reported during bihemispheric sleep, at awakening, and at sleep onset, as well as being associated with a use-dependent process (local sleep). PMID:27471418

  6. Unihemispheric sleep and asymmetrical sleep: behavioral, neurophysiological, and functional perspectives

    Directory of Open Access Journals (Sweden)

    Mascetti GG

    2016-07-01

    Full Text Available Gian Gastone Mascetti Department of General Psychology, University of Padova, Padova, Italy Abstract: Sleep is a behavior characterized by a typical body posture, both eyes' closure, raised sensory threshold, distinctive electrographic signs, and a marked decrease of motor activity. In addition, sleep is a periodically necessary behavior and therefore, in the majority of animals, it involves the whole brain and body. However, certain marine mammals and species of birds show a different sleep behavior, in which one cerebral hemisphere sleeps while the other is awake. In dolphins, eared seals, and manatees, unihemispheric sleep allows them to have the benefits of sleep, breathing, thermoregulation, and vigilance. In birds, antipredation vigilance is the main function of unihemispheric sleep, but in domestic chicks, it is also associated with brain lateralization or dominance in the control of behavior. Compared to bihemispheric sleep, unihemispheric sleep would mean a reduction of the time spent sleeping and of the associated recovery processes. However, the behavior and health of aquatic mammals and birds does not seem at all impaired by the reduction of sleep. The neural mechanisms of unihemispheric sleep are unknown, but assuming that the neural structures involved in sleep in cetaceans, seals, and birds are similar to those of terrestrial mammals, it is suggested that they involve the interaction of structures of the hypothalamus, basal forebrain, and brain stem. The neural mechanisms promoting wakefulness dominate one side of the brain, while those promoting sleep predominates the other side. For cetaceans, unihemispheric sleep is the only way to sleep, while in seals and birds, unihemispheric sleep events are intermingled with bihemispheric and rapid eye movement sleep events. Electroencephalogram hemispheric asymmetries are also reported during bihemispheric sleep, at awakening, and at sleep onset, as well as being associated with a use

  7. Unihemispheric sleep and asymmetrical sleep: behavioral, neurophysiological, and functional perspectives

    Science.gov (United States)

    Mascetti, Gian Gastone

    2016-01-01

    Sleep is a behavior characterized by a typical body posture, both eyes’ closure, raised sensory threshold, distinctive electrographic signs, and a marked decrease of motor activity. In addition, sleep is a periodically necessary behavior and therefore, in the majority of animals, it involves the whole brain and body. However, certain marine mammals and species of birds show a different sleep behavior, in which one cerebral hemisphere sleeps while the other is awake. In dolphins, eared seals, and manatees, unihemispheric sleep allows them to have the benefits of sleep, breathing, thermoregulation, and vigilance. In birds, antipredation vigilance is the main function of unihemispheric sleep, but in domestic chicks, it is also associated with brain lateralization or dominance in the control of behavior. Compared to bihemispheric sleep, unihemispheric sleep would mean a reduction of the time spent sleeping and of the associated recovery processes. However, the behavior and health of aquatic mammals and birds does not seem at all impaired by the reduction of sleep. The neural mechanisms of unihemispheric sleep are unknown, but assuming that the neural structures involved in sleep in cetaceans, seals, and birds are similar to those of terrestrial mammals, it is suggested that they involve the interaction of structures of the hypothalamus, basal forebrain, and brain stem. The neural mechanisms promoting wakefulness dominate one side of the brain, while those promoting sleep predominates the other side. For cetaceans, unihemispheric sleep is the only way to sleep, while in seals and birds, unihemispheric sleep events are intermingled with bihemispheric and rapid eye movement sleep events. Electroencephalogram hemispheric asymmetries are also reported during bihemispheric sleep, at awakening, and at sleep onset, as well as being associated with a use-dependent process (local sleep). PMID:27471418

  8. DETERMINANTS OF PREVENTIVE BEHAVIOR REGARDING CARDIOVASCULAR DISEASES AND RISK FACTORS IN PATIENTS WITH ESSENTIAL HYPERTENSION AND CHRONIC ISCHEMIC HEART DISEASE

    Directory of Open Access Journals (Sweden)

    D. Yu. Platonov

    2016-01-01

    Full Text Available Aim. To analyze potential determinants of preventive behavior (PB in patients with essential hypertension (HT and chronic ischemic heart disease (CIHD, and to establish their significance and hierarchy. Material and methods. Patients with HT (n=285 and CIHD (n=223 were studied. Questioning of all patients was performed to assess the characteristics of their PB. Differentiated multivariate analysis of activity and efficacy of PB determinants was performed in HT and CIHD patients by the method of step-by-step backward logistic regression. Results. Awareness of the cardiovascular diseases (CVD and its prevention (odds ratio [OR] 6.08 as well as high level of general education (OR=2.29 were the most significant determinants of active PB in HT patients. Sufficient social support (OR=3.77, awareness of CVD and its prevention (OR=3.16 were the most significant determinants of active PB in patients with CIHD. Efficacy of PB in patients with HT and CIHD mostly depends on satisfaction of medical service (OR=10.2 and 6.63, respectively, social support (OR=6.25 and 10.5, respectively, adequate awareness of CVD and its prevention (OR, 6.92 and 6.64, respectively. Conclusion. PB activity and efficacy in patients with HT and CIHD depends on many contributing and impeding factors. Disregarding these factors can result in failure in preventive efforts at both individual and population levels.

  9. Fatores de risco cardiovasculares em adolescentes: indicadores biológicos e comportamentais Cardiovascular risk factors in adolescents: biological and behavioral indicators

    OpenAIRE

    Dartagnan Pinto Guedes; Joana Elisabete Ribeiro Pinto Guedes; Decio Sabbatini Barbosa; Jair Aparecido de Oliveira; Luiz Cláudio Reeberg Stanganelli

    2006-01-01

    OBJETIVO: Oferecer informações descritivas e investigar a extensão com que os fatores de risco para doenças cardiovasculares de natureza comportamental estão associados aos fatores de risco biológicos na população jovem. MÉTODOS: Amostra de 452 adolescentes (246 moças e 206 rapazes) com idades entre 15 e 18 anos, selecionados de uma escola de ensino médio da cidade de Londrina, Paraná. Fatores de risco de natureza comportamental foram analisados mediante prática insuficiente de atividade físi...

  10. Perspectives of cardiac care unit nursing staff about developing hospice services in iran for terminally ill cardiovascular patients: A qualitative study

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    Saber Azami-Aghdash

    2015-01-01

    Full Text Available Introduction: The present study was conducted aiming to determine the points of view of cardiac care units′ nursing staff about designing and providing Hospice services in Iran for cardiovascular patients in the final stages of life. Materials and Methods: In this qualitative study, the perspectives of 16 Cardiac Care Unit (CCU nurses selected purposefully among hospitals of Tabriz-Iran University of Medical Sciences were investigated using semi-structured interviews and were analyzed in content analysis method. Results: 33 themes were finally extracted. Some nurses were for and some were against designing and providing Hospice services in Iran. The main reasons identified for supporting this plan included: Possibility of designing and providing these services consistent with high ethical values of Iranian society; approval of authorities due to increasing the load of chronic diseases and aged population; need of families due to the problems in taking care of patients and life concerns; better pain relief and respectful death; decrease of costs as a result of lower usage of diagnostic-therapeutic services, less use of expensive facilities and drugs, and better usage of hospital beds. Conclusion: Growing load of chronic diseases has made the need for Hospice as a necessary issue in Iran. In order to provide these services, studying the viewpoints of health service providers is inevitable. Therefore using and applying the results of this study in planning and policy making about designing and providing these services in Iran for cardiovascular patients in their final stages of lives could be helpful.

  11. The prevalence and correlates of behavioral risk factors for cardiovascular health among Southern Brazil adolescents: a cross-sectional study

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    Barbosa Filho Valter

    2012-08-01

    Full Text Available Abstract Background The adoption of health-related behaviors is an important part of adolescence. This study examined the prevalence and correlates of the isolated and simultaneous presence of behavioral risk factors for cardiovascular health (BRFCH among adolescents in Curitiba, Southern Brazil. Methods A cross-sectional study was performed with 1,628 adolescents (aged 11-17.9 years, 52.5% males that were randomly selected from 44 public schools. Self-report instruments were used to assess the variables. Six BRFCH were analyzed: insufficiently active, excessive TV watching, current alcohol and tobacco use, daily soft drinks consumption and inadequate fruit and vegetable consumption. Sociodemographic and behavioral variables were studied as possible correlates of the presence of BRFCH. Results The BRFCH with the highest prevalence were insufficiently active (50.5%, 95% confidence interval [95% CI]: 48.0-52.9 and daily soft drinks consumption (47.6%, 95% CI: 45.1-50.0. Approximately 30% of the adolescents presented three or more BRFCH simultaneously. Girls, adolescents who did not participate in organized physical activity, and who used computer/video games daily were the main high-risk subgroups for insufficiently active. Boys and those who used computer/video games daily were the high-risk subgroups for daily soft drinks consumption. For excessive TV watching, we identified to be at risk those who were from a high economic class, unemployed, and who used computer/video games daily. For current alcohol use, we identified older adolescents, who were from a high economic class and who worked to be at risk. Older adolescents, who worked and who spent little active time during a physical education class were the high-risk subgroups for current tobacco use. For inadequate fruit and vegetable consumption, we identified those who did not participate in organized physical activity to be at risk. Older adolescents, who were from a high economic class

  12. Relational correlates of interpersonal citizenship behavior: a social network perspective.

    Science.gov (United States)

    Bowler, Wm Matthew; Brass, Daniel J

    2006-01-01

    This study examines the role of social network ties in the performance and receipt of interpersonal citizenship behavior (ICB), one form of organizational citizenship behavior (OCB). A field study involving 141 employees of a manufacturing firm provided evidence that social network ties are related to the performance and receipt of ICB. Results support hypothesized relationships, which are based on social exchange theory, suggesting strength of friendship is related to performance and receipt of ICB. Support was also found for impression management-based hypotheses suggesting that asymmetric influence and 3rd-party influence are related to the performance and receipt of ICB. These relationships were significant when controlling for job satisfaction, commitment, procedural justice, hierarchical level, demographic similarity, and job similarity. Implications and directions for future research are addressed. PMID:16435939

  13. The creative consumer : exploring consumer behavior from a creativity perspective

    OpenAIRE

    Engeset, Marit G.

    2010-01-01

    This research focuses on consumer creativity and uses frameworks from creativity theory to  understand consumer behavior. Because this is a relatively new field of inquiry, the work belongs  mainly in the context of discovery. Therefore, the topic was approached in an open, exploratory  manner.  Instead of formal hypotheses, a set of propositions and models were developed and tested  empirically in a field study.  Four concepts relevant to the understanding of consumer behavior...

  14. Preventive Intervention for Early Childhood Behavioral Problems: An Ecological Perspective

    OpenAIRE

    Shepard, Stephanie A.; Dickstein, Susan

    2009-01-01

    The purpose of this paper is to highlight the importance of preventive interventions targeting parents when addressing early childhood behavior problems. We briefly review evidence-based parent management training programs (PMT), focusing on one particular program, the Incredible Years Series (IY). Next, we discuss the barriers to embedding evidence-based practice like IY in community contexts, and demonstrate how early childhood mental health consultation can be used to enhance community cap...

  15. A sociogenomic perspective on neuroscience in organizational behavior

    OpenAIRE

    Spain, Seth M.; Harms, P. D.

    2014-01-01

    We critically examine the current biological models of individual organizational behavior, with particular emphasis on the roles of genetics and the brain. We demonstrate how approaches to biology in the organizational sciences assume that biological systems are simultaneously causal and essentially static; that genotypes exert constant effects. In contrast, we present a sociogenomic approach to organizational research, which could provide a meta-theoretical framework for understanding organi...

  16. THE PERCEIVED ETHICAL BEHAVIOR OF BANKERS: A NORTH AFRICAN PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    Wafa M’SALLEM

    2011-06-01

    Full Text Available This research aims to examine the impact of the ethical dimension of selling behavior on some marketing relational variables in the banking sector: satisfaction, trust, commitment and loyalty. Structural equations modelling (SEM is used to assess the simultaneous effects of the predictive variables. An empirical survey confirms the impact of the ethical dimension on the trust. The satisfaction has an effect on the customer trust which influences his commitment and loyalty.

  17. Political behavior, social responsibility, and perceived corruption: a structuration perspective

    OpenAIRE

    Yadong Luo

    2006-01-01

    This study unites the three lenses – political behavior, corporate social responsibility, and corruption – and evaluates the way in which multinational enterprises (MNEs) manage political and social forces in a foreign emerging market. Using the theory of structuration as the conceptual foundation, we propose that an MNE's propensity to cooperate with the host government is positively related to its philanthropic contribution and resource accommodation, whereas its propensity to be assertive ...

  18. Teenage pregnancy in the United Kingdom: a behavioral ecological perspective

    OpenAIRE

    Dickins, Thomas E.; Johns, Sarah E; Chipman, Abby

    2012-01-01

    In this paper we describe teenage pregnancy and motherhood in the United Kingdom. This has been regarded as a key social policy issue for some time and is the focus of policy intervention under the current administration. We argue that policy has been based on simple models of teenage pregnancy that have failed to take into account the complex biological nature of reproductive behavior. Our claim is that the U.K. government would be well advised to take a life-history approach to this issue, ...

  19. Evolutionary and neuropsychological perspectives on addictive behaviors and addictive substances: relevance to the "food addiction" construct

    OpenAIRE

    Davis C

    2014-01-01

    Caroline Davis School of Kinesiology and Health Science, York University, Toronto, ON, Canada Abstract: It has been argued that food cannot be "addictive", unlike conventional drugs of abuse, because it is an essential part of life. In this paper, evidence is reviewed, largely from an evolutionary psychobiological perspective, that plant-based psychoactive drugs (such as those derived from the opium poppy and the coca leaf) and gambling-related behaviors were once adaptive for huma...

  20. Information Security on the Web and App Platforms: An Economic and Socio-Behavioral Perspective

    OpenAIRE

    Chia, Pern Hui

    2012-01-01

    Various security measures are ineffective having been designed without adequate usability and economic considerations. The primary objective of this thesis is to add an economic and socio-behavioral perspective to the traditional computer science research in information security. The resulting research is interdisciplinary, and the papers combine different approaches, ranging from analytic modeling to empirical measurements and user studies. Contributing to the fields of usable security and s...

  1. Test of the Behavioral Perspective Model in the Context of an E-Mail Marketing Experiment

    Science.gov (United States)

    Sigurdsson, Valdimar; Menon, R. G. Vishnu; Sigurdarson, Johannes Pall; Kristjansson, Jon Skafti; Foxall, Gordon R.

    2013-01-01

    An e-mail marketing experiment based on the behavioral perspective model was conducted to investigate consumer choice. Conversion e-mails were sent to two groups from the same marketing database of registered consumers interested in children's books. The experiment was based on A-B-A-C-A and A-C-A-B-A withdrawal designs and consisted of…

  2. Perspectives on Some Controversies in Cardiovascular Disease Risk Assessment in the Pharmaceutical Development of Glucose-Lowering Medications.

    Science.gov (United States)

    Hoogwerf, Byron J; Manner, David H; Fu, Haoda; Moscarelli, Elena; Gaydos, Brenda L; Heine, Robert J

    2016-08-01

    The U.S. Food and Drug Administration (FDA) issued guidance on requirements to assess cardiovascular disease (CVD) risk with drugs being developed for approval for clinical use. The guidance was triggered by a meta-analysis published by Nissen and Wolski that suggested an increased risk for myocardial infarction with the use of rosiglitazone. This article discusses controversies around CVD trials in diabetes beginning with the University Group Diabetes Program. This is followed by a brief description of the FDA guidance for evaluating CVD risk with glucose-lowering medications. Limitations of meta-analyses of data from phase 2 and 3 (phase 2/3) trials to inform CVD risk are highlighted. These include the differences between patient characteristics in phase 2/3 trials and those in cardiovascular outcome trials (CVOTs) and the relatively short exposure time in phase 2/3 trials. The differences may partly explain the observed disparity between phase 2/3 meta-analyses and the results of completed CVOTs. Approaches to understanding CVD risk with a new medication should get to the answer about risk as efficiently as possible to minimize any potential harm to patients. In that context, we discuss options for clinical trial design and an alternative approach for statistical analyses. PMID:27440836

  3. Adherence With Therapeutic Regimens: Behavioral and Pharmacoeconomic Perspectives.

    Science.gov (United States)

    Giannetti, Vincent J; Kamal, Khalid M

    2016-04-01

    There is an extensive literature regarding nonadherence with both therapeutic regimens and medication. This literature includes reviews of empirical research regarding the factors associated with nonadherence. Health care system, provider, and patient factors as well as the nature of the illness and therapeutic regimen all effect adherence rates. Different behavioral models for adherence counseling such as the Health Belief Model, the Theory of Reasoned Action, the Medication Interest Model, and Motivational Interviewing have also been reported in the research literature. This article will discuss the development of a brief model for patient counseling with specific techniques illustrated for pharmacists based on empirical findings that have demonstrated effectiveness in the adherence research literature. In addition, the article will address the measurement of the economic impact of medication nonadherence and propose a framework for assessing the cost-effectiveness of pharmacist counseling to increase adherence. The problem of nonadherence has significant effects upon health care expenditures through increase in physician's visits, emergency department incidents, rehospitalizations, and nursing home readmissions. Thus, the overall goal is to assist the pharmacist in developing a brief adherence counseling program in community pharmacy and evaluating the economic feasibility of the intervention demonstrating the value-added proposition of pharmacist intervention. PMID:25292442

  4. Effects of nutrition and exercise health behaviors on predicted risk of cardiovascular disease among workers with different body mass index levels.

    Science.gov (United States)

    Huang, Jui-Hua; Huang, Shu-Ling; Li, Ren-Hau; Wang, Ling-Hui; Chen, Yu-Ling; Tang, Feng-Cheng

    2014-05-01

    Workplace health promotion programs should be tailored according to individual needs and efficient intervention. This study aimed to determine the effects of nutrition and exercise health behaviors on predicted risk for cardiovascular disease (CVD) when body mass index (BMI) is considered. In total, 3350 Taiwanese workers were included in this cross-sectional study. A self-reported questionnaire was used to measure their nutrition and exercise behaviors. Data on anthropometric values, biochemical blood determinations, and predicted CVD risk (using the Framingham risk score) were collected. In multiple regression analyses, the nutrition behavior score was independently and negatively associated with CVD risk. Exercise was not significantly associated with the risk. However, the interactive effect of exercise and BMI on CVD risk was evident. When stratified by BMI levels, associations between exercise and CVD risk were statistically significant for ideal weight and overweight subgroups. In conclusion, nutrition behavior plays an important role in predicting the CVD risk. Exercise behavior is also a significant predictor for ideal weight and overweight workers. Notably, for underweight or obese workers, maintaining health-promoting exercise seems insufficient to prevent the CVD. In order to improve workers' cardiovascular health, more specific health-promoting strategies should be developed to suit the different BMI levels. PMID:24785541

  5. Effects of Nutrition and Exercise Health Behaviors on Predicted Risk of Cardiovascular Disease among Workers with Different Body Mass Index Levels

    Directory of Open Access Journals (Sweden)

    Jui-Hua Huang

    2014-04-01

    Full Text Available Workplace health promotion programs should be tailored according to individual needs and efficient intervention. This study aimed to determine the effects of nutrition and exercise health behaviors on predicted risk for cardiovascular disease (CVD when body mass index (BMI is considered. In total, 3350 Taiwanese workers were included in this cross-sectional study. A self-reported questionnaire was used to measure their nutrition and exercise behaviors. Data on anthropometric values, biochemical blood determinations, and predicted CVD risk (using the Framingham risk score were collected. In multiple regression analyses, the nutrition behavior score was independently and negatively associated with CVD risk. Exercise was not significantly associated with the risk. However, the interactive effect of exercise and BMI on CVD risk was evident. When stratified by BMI levels, associations between exercise and CVD risk were statistically significant for ideal weight and overweight subgroups. In conclusion, nutrition behavior plays an important role in predicting the CVD risk. Exercise behavior is also a significant predictor for ideal weight and overweight workers. Notably, for underweight or obese workers, maintaining health-promoting exercise seems insufficient to prevent the CVD. In order to improve workers’ cardiovascular health, more specific health-promoting strategies should be developed to suit the different BMI levels.

  6. Conflict perspectives in analyzing and understanding organizatioanal behavior

    Directory of Open Access Journals (Sweden)

    Ahmad Shukri bin Mohd Nain

    2004-12-01

    Western civilization. Thus, this article is an attempt to analyze conflict as a significant intellectual paradigm and approach in understanding organizational behavior.

  7. Cardiovascular Disease Burden: Evolving Knowledge of Risk Factors in Myocardial Infarction and Stroke through Population-Based Research and Perspectives in Global Prevention

    Directory of Open Access Journals (Sweden)

    GUSTAVO B.F. OLIVEIRA

    2015-08-01

    Full Text Available Current knowledge and research perspectives on the top ranking causes of mortality worldwide, i.e., ischemic heart disease and cerebrovascular diseases have developed rapidly. In fact, until recently, it was considered that only half of the myocardial infarctions were due to traditional risk factors such as hypertension, hypercholesterolemia, smoking and diabetes. In addition, most of the available evidence of incidence, risk factors, and clinical outcomes, if not all of it, was derived from studies conducted in developed countries, which included lower proportion of female individuals and with low ethnic diversity. Recent reports by the WHO have provided striking public health information, i.e., the global burden of cardiovascular mortality for the next decades is expected to predominantly occur among developing countries. Therefore, multi-ethnic population-based research including prospective cohorts and, when appropriate, case-control studies, is warranted. These studies should be specifically designed to ascertain key public health measures such as geographic variations in noncommunicable diseases, diagnosis of traditional and potential newly discovered risk factors, causes of death and disability, and gaps for improvement in healthcare prevention (both primary and secondary and specific treatments. As an example, a multinational, multiethnic population-based cohort study is the Prospective Urban and Rural Epidemiology (PURE study, which is the largest global initiative of 150,000 adults aged 35-70 yrs, looking at environmental, societal and biological influences on obesity and chronic health conditions such as ischemic heart disease, stroke and cancer among urban and rural communities in low-, middle-, and high-income countries, with national, community, household and individual-level data. Implementation of population-based strategies is crucial to optimizing limited health system resources while improving care and cardiovascular morbidity

  8. A new perspective on behavioral inconsistency and neural noise in aging: Compensatory speeding of neural communication

    Directory of Open Access Journals (Sweden)

    S. Lee Hong

    2012-09-01

    Full Text Available This paper seeks to present a new perspective on the aging brain. Here, we make connections between two key phenomena of brain aging: 1 increased neural noise or random background activity; and 2 slowing of brain activity. Our perspective proposes the possibility that the slowing of neural processing due to decreasing nerve conduction velocities leads to a compensatory speeding of neuron firing rates. These increased firing rates lead to a broader distribution of power in the frequency spectrum of neural oscillations, which we propose, can just as easily be interpreted as neural noise. Compensatory speeding of neural activity, as we present, is constrained by the: A availability of metabolic energy sources; and B competition for frequency bandwidth needed for neural communication. We propose that these constraints lead to the eventual inability to compensate for age-related declines in neural function that are manifested clinically as deficits in cognition, affect, and motor behavior.

  9. The Covariation of Antisocial Behavior and Substance Use in Adolescence: A Behavioral Genetic Perspective

    Science.gov (United States)

    McAdams, Tom; Rowe, Richard; Rijsdijk, Fruhling; Maughan, Barbara; Eley, Thalia C.

    2012-01-01

    Multivariate genetic studies have revealed genetic correlations between antisocial behavior (ASB) and substance use (SU). However, ASB is heterogeneous, and it remains unclear whether all forms are similarly related to SU. The present study examines links between cannabis use, alcohol consumption, and aggressive and delinquent forms of ASB using a…

  10. The Use of Behavior Change Techniques and Theory in Technologies for Cardiovascular Disease Prevention and Treatment in Adults: A Comprehensive Review.

    Science.gov (United States)

    Winter, Sandra J; Sheats, Jylana L; King, Abby C

    2016-01-01

    This review examined the use of health behavior change techniques and theory in technology-enabled interventions targeting risk factors and indicators for cardiovascular disease (CVD) prevention and treatment. Articles targeting physical activity, weight loss, smoking cessation and management of hypertension, lipids and blood glucose were sourced from PubMed (November 2010-2015) and coded for use of 1) technology, 2) health behavior change techniques (using the CALO-RE taxonomy), and 3) health behavior theories. Of the 984 articles reviewed, 304 were relevant (240=intervention, 64=review). Twenty-two different technologies were used (M=1.45, SD=+/-0.719). The most frequently used behavior change techniques were self-monitoring and feedback on performance (M=5.4, SD=+/-2.9). Half (52%) of the intervention studies named a theory/model - most frequently Social Cognitive Theory, the Trans-theoretical Model, and the Theory of Planned Behavior/Reasoned Action. To optimize technology-enabled interventions targeting CVD risk factors, integrated behavior change theories that incorporate a variety of evidence-based health behavior change techniques are needed. PMID:26902519

  11. Naturalistic and Structured Assessments of Prosocial Behavior in Preschool Children: The Influence of Empathy and Perspective Taking.

    Science.gov (United States)

    Iannotti, Ronald J.

    1985-01-01

    Interrelationship of different categories of prosocial behavior different assessment procedures, and role of empathy and perspective taking were examined. Prosocial behavior in preschool children was assessed using three different approaches: naturalistic observation, structured measures, and teacher ratings. Results indicated preschool children…

  12. Cardiovascular Risk Factors and Physical Activity Behavior among Elementary School Personnel: Baseline Results from the ACTION! Worksite Wellness Program

    Science.gov (United States)

    Webber, Larry S.; Rice, Janet C.; Johnson, Carolyn C.; Rose, Donald; Srinivasan, Sathanur R.; Berenson, Gerald S.

    2012-01-01

    Background: Although the prevalence of obesity is increasing during adulthood, there have been few assessments of obesity, cardiovascular risk factors, and levels of physical activity among adult elementary school staff. Methods: Data were collected from 745 African-American and White female school personnel in a suburban school district in…

  13. Introduction to the special issue Disparities in cardiovascular health: Examining the contributions of social and behavioral factors.

    Science.gov (United States)

    Ruiz, John M; Brondolo, Elizabeth

    2016-04-01

    Cardiovascular disease (CVD) is the leading cause of disability and death in the United States, accounting for 31.3% of all deaths in a given year (Mozaffarian et al., 2016). Importantly, risk factors for CVD, the incidence of CVD, and adverse outcomes associated with CVD are not experienced equally by all segments of society. This special issue is an opportunity to highlight contributions of health psychology to the understanding of disparities in cardiovascular health. The 12 papers published here include eight full manuscripts, two brief reports, and two invited commentaries. Sampling in these studies is largely restricted to healthy adults, with one paper focused on early life adversity and subsequent health in adolescents and a second examining social support in adolescence as a predictor of CVD risk in adulthood. These papers offer windows into cuttingedge themes, methodologies, challenges, and future directions in understanding psychosocial factors and sociocultural sequelae as they relate to cardiovascular health disparities. Examined together, the papers begin to elucidate the ways in which the social context drives biopsychological processes that contribute to cardiovascular health disparities. (PsycINFO Database Record PMID:27018721

  14. Prediction and Cross-Situational Consistency of Daily Behavior across Cultures: Testing Trait and Cultural Psychology Perspectives.

    Science.gov (United States)

    Church, A Timothy; Katigbak, Marcia S; Reyes, Jose Alberto S; Salanga, Maria Guadalupe C; Miramontes, Lilia A; Adams, Nerissa B

    2008-10-01

    Trait and cultural psychology perspectives on the cross-situational consistency of behavior, and the predictive validity of traits, were tested in a daily process study in the United States (N = 68), an individualistic culture, and the Philippines (N = 80), a collectivistic culture. Participants completed the Revised NEO Personality Inventory (Costa & McCrae, 1992) and a measure of self-monitoring, then reported their daily behaviors and associated situational contexts for approximately 30 days. Consistent with trait perspectives, the Big Five traits predicted daily behaviors in both cultures, and relative (interindividual) consistency was observed across many, although not all, situational contexts. The frequency of various Big Five behaviors varied across relevant situational contexts in both cultures and, consistent with cultural psychology perspectives, there was a tendency for Filipinos to exhibit greater situational variability than Americans. Self-monitoring showed some ability to account for individual differences in situational variability in the American sample, but not the Filipino sample. PMID:22146866

  15. Analysis of internationalization process of IBQ Britanite under the perspective of the behavioral approach

    Directory of Open Access Journals (Sweden)

    Fábio Dal-Soto

    2013-11-01

    Full Text Available The process of internationalization of companies has proceeded in different ways and contexts. Among the models that guide and explain the moves made by companies into the international market, this study is on the behavioral perspective of internationalization theories  The main objective of this paper is to analyze, in the light of the theoretical assumptions of the behavioral approach, the process of internationalization of IBQ Britanite, leader in the Brazilian civil explosives and providing services in blasting rocks . Therefore, the study is characterized by bias qualitative study using a single case study that answers the five questions of the internationalization process: why, what, when, where and how companies internationalize their activities. The results show that the process of internationalization of the company came to advantages gained both domestically and restrictions growth. Throughout his international career, the company gradually progressed in export activities, and also for stages greater commitment to the foreign market through joint ventures and production subsidiary.

  16. Relating spatial perspective taking to the perception of other's affordances: providing a foundation for predicting the future behavior of others

    OpenAIRE

    Sarah H Creem-Regehr; Gagnon, Kyle T.; Geuss, Michael N.; Stefanucci, Jeanine K.

    2013-01-01

    Understanding what another agent can see relates functionally to the understanding of what they can do. We propose that spatial perspective taking and perceiving other's affordances, while two separate spatial processes, together share the common social function of predicting the behavior of others. Perceiving the action capabilities of others allows for a common understanding of how agents may act together. The ability to take another's perspective focuses an understanding of action goals so...

  17. Cardiovascular modeling and diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Kangas, L.J.; Keller, P.E.; Hashem, S.; Kouzes, R.T. [Pacific Northwest Lab., Richland, WA (United States)

    1995-12-31

    In this paper, a novel approach to modeling and diagnosing the cardiovascular system is introduced. A model exhibits a subset of the dynamics of the cardiovascular behavior of an individual by using a recurrent artificial neural network. Potentially, a model will be incorporated into a cardiovascular diagnostic system. This approach is unique in that each cardiovascular model is developed from physiological measurements of an individual. Any differences between the modeled variables and the variables of an individual at a given time are used for diagnosis. This approach also exploits sensor fusion to optimize the utilization of biomedical sensors. The advantage of sensor fusion has been demonstrated in applications including control and diagnostics of mechanical and chemical processes.

  18. Cardiovascular behavior during rehabilitation after coronary artery bypass grafting Comportamento cardiovascular durante a reabilitação após cirurgia de revascularização do miocárdio

    Directory of Open Access Journals (Sweden)

    Fernando de Souza Botega

    2010-12-01

    Full Text Available OBJECTIVE: The aim of the present study was to assess the behavior of cardiovascular variables during an in-hospital cardiovascular rehabilitation program in patients following myocardial revascularization surgery. METHODS: A total of 14 patients (mean age: 55.4 ± 6.4 years, 78.6% male participated in the study, all of whom had a previous diagnosis of coronary insufficiency and indication for elective surgery. The protocol consisted of a group of low-impact (2-3 METs upper/lower extremity and walking exercises performed both pre and post-operatively (3rd and 4th days. The following variables were evaluated at rest and following the exercise program: heart rate (HR, bpm; systolic arterial pressure (SAP, mmHg; diastolic arterial pressure (DAP, mmHg; mean arterial pressure (MAP, mmHg; double product (DPr, bpm/mmHg; and the Rating of Perceived Exertion (RPE scale. RESULTS: There was a significant increase in HR and DPr in the individual analysis (POBJETIVO: O objetivo do presente estudo foi avaliar o comportamento das variáveis cardiovasculares durante um programa de reabilitação cardiovascular hospitalar em pacientes submetidos à cirurgia de revascularização do miocárdio. MÉTODOS: Um total de 14 pacientes (idade média: 55,4 ± 6,4 anos, 78,6% do sexo masculino participaram do estudo, todos apresentavam diagnóstico prévio de insuficiência coronariana e indicação de cirurgia eletiva. O protocolo consistiu de um grupo de exercícios de baixo impacto (2-3 METs para extremidade superior e inferior e exercícios de caminhada realizados no pré e pós-operatório (3 e 4 dias. As seguintes variáveis foram avaliadas em repouso e após o programa de exercício: frequência cardíaca (FC, bpm, pressão arterial sistólica (PAS, mmHg, pressão arterial diastólica (PAD, mmHg, pressão arterial média (MAP,mmHg, duplo produto (DPr, bpm/mmHg e escala de Índice de Percepção de Esforço (IPE. RESULTADOS: Houve aumento significativo da FC e DPr

  19. Evolutionary and neuropsychological perspectives on addictive behaviors and addictive substances: relevance to the "food addiction" construct

    Directory of Open Access Journals (Sweden)

    Davis C

    2014-12-01

    Full Text Available Caroline Davis School of Kinesiology and Health Science, York University, Toronto, ON, Canada Abstract: It has been argued that food cannot be "addictive", unlike conventional drugs of abuse, because it is an essential part of life. In this paper, evidence is reviewed, largely from an evolutionary psychobiological perspective, that plant-based psychoactive drugs (such as those derived from the opium poppy and the coca leaf and gambling-related behaviors were once adaptive for human health and survival in a similar manner as energy-based foods were for nourishment. "Evolutionary mismatch" viewpoints contend that certain behaviors were enhanced during the hunter-gatherer lifestyle – from which our genetic endowment had its origins – because they bestowed both survival and reproductive advantages to the species. However, in the context of advanced technology and other rapid environmental changes, these same behaviors have tended to become maladaptive and greatly overexpressed. Similar to the manufactured purification of psychotropic plant-based substances, the reward impact of processed and hyperpalatable foods, with their high levels of sugar, fat, and salt, is much increased from foods produced in nature. It is concluded therefore that what was once beneficial and necessary for our survival has been altered and ultraprocessed into edible products that may be disadvantageous and potentially addictive. Keywords: food addiction, evolution, drugs, gambling

  20. Epidemiology of Cardiovascular Diseases.

    Science.gov (United States)

    Jenkins, C. David

    1988-01-01

    Reviews epidemiological studies of cardiovascular diseases especially coronary heart disease (CHD), to document their major public health importance, changes in mortality during this century, and international comparisons of trends. Finds major risk factors for CHD are determined in large part by psychosocial and behavioral mechanisms. Asserts…

  1. A Preliminary Examination of Teachers’ and Students’ Perspectives on Autonomy-Supportive Instructional Behaviors

    Directory of Open Access Journals (Sweden)

    Betsy Ng

    2015-06-01

    Full Text Available The present study focuses on the perspectives of teachers and students in Singapore schools after an autonomy-supportive classroom intervention. Nurturing of students to become motivated and self-regulated learners can be achieved by promoting an autonomy-supportive learning climate. This study examines the perspectives of teachers and students in an in-depth and meaningful manner after the classroom intervention. Through students’ viewpoints, teachers can understand their structure of teaching style and students’ expectations. Findings of semi-structured interviews with students and teachers were analyzed, with emerging themes discussed in the context of literature. Based on qualitative data, this preliminary study explores a rich and meaningful insight to students’ expectations of their teachers and teachers’ expectations towards their students. The qualitative data provided relevant and practical insights into the classroom intervention, suggesting that teachers should be aware of their instructional behaviors in class as such acts might have ramification on students’ perception, motivation and learning. Limitations and implications are also discussed.

  2. Prediction and Cross-Situational Consistency of Daily Behavior across Cultures: Testing Trait and Cultural Psychology Perspectives

    OpenAIRE

    Church, A. Timothy; Katigbak, Marcia S.; Reyes, Jose Alberto S.; Salanga, Maria Guadalupe C.; Miramontes, Lilia A.; Adams, Nerissa B.

    2008-01-01

    Trait and cultural psychology perspectives on the cross-situational consistency of behavior, and the predictive validity of traits, were tested in a daily process study in the United States (N = 68), an individualistic culture, and the Philippines (N = 80), a collectivistic culture. Participants completed the Revised NEO Personality Inventory (Costa & McCrae, 1992) and a measure of self-monitoring, then reported their daily behaviors and associated situational contexts for approximately 30 da...

  3. Observing Engineering Student Teams from the Organization Behavior Perspective Using Linguistic Analysis of Student Reflections and Focus Group Interviews

    Science.gov (United States)

    Kearney, Kerri S.; Damron, Rebecca; Sohoni, Sohum

    2015-01-01

    This paper investigates group/team development in computer engineering courses at a University in the Central USA from the perspective of organization behavior theory, specifically Tuckman's model of the stages of group development. The investigation, conducted through linguistic analysis of student reflection essays, and through focus group…

  4. A Behavioral Perspective of Childhood Trauma and Attachment Issues: Toward Alternative Treatment Approaches for Children with a History of Abuse

    Science.gov (United States)

    Prather, Walter; Golden, Jeannie A.

    2009-01-01

    Attachment theory provides a useful conceptual framework for understanding trauma and the treatment of children who have been abused. This article examines childhood trauma and attachment issues from the perspective of behavior analysis, and provides a theoretical basis for two alternative treatment models for previously abused children and their…

  5. Do brooding and polygamy behaviors exist on Cretaceous oviraptoroid dinosaurs of China: a paleobiological perspective

    Science.gov (United States)

    Yang, T.-R.; Cheng, Y.-N.; Yang, K.-M.

    2012-04-01

    Brooding, parental care, and polygamy represent three different stages in bird's reproduction. The oringin of these behaviors is still in debate. Several samples excavated from China strengthen the phylogenetic relationship between birds and dinosaurs, for example, feathered dinosaurs, paired-eggs in pelvic region of an oviraptorid dinosaur, and small theropod fossils. Previous studies in past two decades, including an oviraptor sitting on a clutch and comparison of the ratio of clutch-volume to adult-body-size between Aves and Mesozoic dinosaurs, proposed that these behaviors had appeared on some Cretaceous theropods (e.g., oviraptor and troodon). These researches also indicate the possibility of endothermy and male care first. In conclusion, this reproduction strategy might support females having more remnant energy to build a larger clutch contributed eggs from multiple females, and brooded by males only. From our cluster analysis through paleoecological perspectives, the eggs in Cretaceous oviraptor's nest should not be corporately laid by multiple females. In morphological observation, the fossilized clutches from Ganzhou, Jiangxi, Mainland China, are 2-layered interbeded with matrix of reddish-brown siltstone or clays. The inner-layer eggs are hampered from directly contacting with adult dinosaurs body. Furthermore, the blunt ends of the eggs point to the center, and incline away forming a mound-shape nest, which is completely different from those of precocial and male-caring megapode. The ornamentation of eggshell surface and microstructures from thin sections of eggs from oviraptors and ostrich (Struthioniformes) are totally different. Comparison of thickness in different part of oviraptor's egg also reveal possible physiological structure in the egg and ecological behaviors. The detailed comparison implies that the Mesozoic oviraptoroid dinosaurs hold absolutely different incubation and caring behaviors from extant birds. We propose an alternative

  6. Down syndrome: a cardiovascular perspective

    NARCIS (Netherlands)

    J.C. Vis; M.G.J. Duffels; M.M. Winter; M.E. Weijerman; J.M. Cobben; S.A. Huisman; B.J.M. Mulder

    2009-01-01

    This review focuses on the heart and vascular system in patients with Down syndrome. A clear knowledge on the wide spectrum of various abnormalities associated with this syndrome is essential for skilful management of cardiac problems in patients with Down syndrome. Epidemiology of congenital heart

  7. Attacking and Defending Perspective of E-Crime Behavior and Psychology: A Systemic Dynamic Simulation Approach

    Directory of Open Access Journals (Sweden)

    Deng-Yiv Chiu

    2010-12-01

    Full Text Available Cybercrime is a worsening problem that can lead to loss of financial and personal information. However, ecrime is particular hard to detect since internet is boundless that make evidence hard to collect. Additionally, compare to others crime issues, e-crime is an emerging crime type thus previous crime theories should be refined and new methods of predicting e-crime should be further developed. In this research, we constructed a system dynamic simulation model from both e-crime attacking and defending side respectively. Various decision variables that related to behavior and psychology perspectives of victim and offender were added to proposed model. Furthermore, the actual ecrime data of Taiwan from Year 2000 to 2008 for cyber fraud (CF and offend computer usage (OCU are then further verified the proposed model. As the simulation result demonstrated, the accuracy rate of e-crime predication can be achieved about 80%. Additionally, some interest parameters are also revealed, such as the recidivism rate and report rate of victim were unknown in previous research. Finally, via inference of simulation result, some suggestions are also proposed to reduce potential e-crime behavior.

  8. Parents' empathic perspective taking and altruistic behavior predicts infants' arousal to others' emotions.

    Science.gov (United States)

    Upshaw, Michaela B; Kaiser, Cheryl R; Sommerville, Jessica A

    2015-01-01

    Empathy emerges in children's overt behavior around the middle of the second year of life. Younger infants, however, exhibit arousal in response to others' emotional displays, which is considered to be a precursor to fully developed empathy. The goal of the present study was to investigate individual variability in infants' arousal toward others' emotional displays, as indexed by 12- and 15-month-old infants' (n = 49) pupillary changes in response to another infant's emotions, and to determine whether such variability is linked to parental empathy and prosociality, as indexed via self-report questionnaires. We found that increases in infants' pupil dilation in response to others' emotional displays were associated with aspects of parental empathy and prosociality. Specifically, infants who exhibited the greatest arousal in response to others' emotions had parents who scored highly on empathic perspective taking and self-reported altruism. These relations may have been found because arousal toward others' emotions shares certain characteristics with empathic and prosocial dispositions. Together, these results demonstrate the presence of early variability in a precursor to mature empathic responding in infancy, which is meaningfully linked to parents' empathic dispositions and prosocial behaviors. PMID:25883577

  9. Clustering of cardiovascular behavioral risk factors and blood pressure among people diagnosed with hypertension: a nationally representative survey in China.

    Science.gov (United States)

    Li, Yichong; Feng, Xiaoqi; Zhang, Mei; Zhou, Maigeng; Wang, Ning; Wang, Limin

    2016-01-01

    This study aimed to examine association between the number of behavioral risk factors and blood pressure (BP) level among a nationally representative sample of Chinese people diagnosed with hypertension. A total of 31,694 respondents aged 18+ years with diagnosed hypertension were extracted from the 2013-2014 China Chronic Disease and Risk Factor Surveillance. BP of each respondent was classified into six levels according to criteria in 2007 Guidelines for the Management of Arterial Hypertension. Information for smoking, alcohol drinking, fruit and vegetables consumption, physical inactivity, and overweight and obesity were obtained. The average number of risk factors was determined by BP level to explore potential risk factor clustering. Ten generalized proportional odds models were used to examine association between clustering of behavioral risk factors and BP level. A clear gradient between the number of behavioral risk factors and BP level was observed for men and women (P management among people diagnosed with hypertension. PMID:27279273

  10. A renaissance in residential behavior analysis? A historical perspective and a better way to help people with challenging behavior

    OpenAIRE

    Holburn, Steve

    1997-01-01

    After a slow start, the popularity of applied behavior analysis for people with severe behavior problems peaked in the 1970s and was then battered down by the effects of methodological behaviorism, the aversives controversy, overregulation, and the inherent limitations of congregate living. Despite the ethical, technical, and conceptual advancements in behavior analysis, many people with challenging behavior live in futile environments in which the behavior analyst can only tinker. A radicall...

  11. Effects of Emotional Stimuli on Cardiovascular Responses in Patients with Essential Hypertension Based on Brain/Behavioral Systems

    OpenAIRE

    Mohammadreza Taban Sadeghi; Hossein Namdar; Shahram Vahedi; Naser Aslanabadi; Davoud Ezzati; Babak Sadeghi

    2013-01-01

    Introduction: Effects of emotional stimuli on hemodynamics in patients with essential hypertension based on brain/behavioral systems have not been studied broadly. Methods: Eighty five essential hypertensive male patients who had completed Carver-White BIS/BAS scale were enrolled to the study. Later, 25 BIS and 25 BAS patients were selected and their blood pressure and heart rate were recorded prior to stimuli induction. Participants were then exposed to stressor pictures. After that, 15 m...

  12. Molecular Mechanisms of Cardiovascular Aging

    Directory of Open Access Journals (Sweden)

    Anna Meiliana

    2013-12-01

    Full Text Available BACKGROUND: The average lifespan of humans is increasing, and with it the percentage of people entering the 65 and older age group is growing rapidly and will continue to do so in the next 20 years. Within this age group, cardiovascular disease will remain the leading cause of death, and the cost associated with treatment will continue to increase. Aging is an inevitable part of life and unfortunately poses the largest risk factor for cardiovascular disease. CONTENT: We provide an overview of some of the molecular mechanisms involved in regulating lifespan and health, including mitochondria, telomeres, stem cells, sirtuins, Adenosine Monophosphate-activated Protein Kinase, Mammalian Target of Rapamycin and Insulin-like Growth Factor 1. We also provide future perspectives of lifespan and health, which are intimately linked fields. SUMMARY: Aging remains the biggest non-modifiable risk factor for cardiovascular disease. The biological, structural and mechanical changes in senescent cardiovascular system are thought to contribute in increasing incidence of cardiovascular disease in aging. Understanding the mechanisms contributing to such changes is therefore crucial for both prevention and development of treatment for cardiovascular diseases. KEYWORDS: cardiovascular aging, mitochondria, telomeres, sirtuin, stem cells.

  13. A Preliminary Investigation of User Perception and Behavioral Intention for Different Review Types: Customers and Designers Perspective

    OpenAIRE

    Atika Qazi; Ram Gopal Raj; Muhammad Tahir; Mahwish Waheed; Saif Ur Rehman Khan; Ajith Abraham

    2014-01-01

    Existing opinion mining studies have focused on and explored only two types of reviews, that is, regular and comparative. There is a visible gap in determining the useful review types from customers and designers perspective. Based on Technology Acceptance Model (TAM) and statistical measures we examine users’ perception about different review types and its effects in terms of behavioral intention towards using online review system. By using sample of users (N=400) and designers (N=106), curr...

  14. Therapist and patient perspectives on cognitive-behavioral therapy for older adults with hoarding disorder: A collective case study

    OpenAIRE

    Ayers, Catherine R.; Bratiotis, Christiana; Saxena, Sanjaya; Wetherell, Julie Loebach

    2012-01-01

    Utilizing a qualitative approach, the current study explored therapist and patient perspectives on a specialized cognitive-behavioral therapy (CBT) protocol for clinically significant hoarding in older adult patients. Data were derived from the following sources: (1) therapist observation; (2) CBT consultant observation; (3) clinical treatment notes; (4) participant feedback, including a focus group; and (5) participant in-session notes and completed homework assignments. Our findings showed ...

  15. Cardiovascular health knowledge and behavior in patient attendants at four tertiary care hospitals in Pakistan – a cause for concern

    Directory of Open Access Journals (Sweden)

    Afzal Atif

    2005-11-01

    Full Text Available Abstract Background Knowledge about coronary heart disease (CHD and its risk factors is an important pre-requisite for an individual to implement behavioral changes leading towards CHD prevention. There is scant data on the status of knowledge about CHD in the general population of Pakistan. The objective of this study was to assess knowledge of CHD in a broad Pakistani population and identify the factors associated with knowledge. Methods Cross sectional study was carried out at four tertiary care hospitals in Pakistan using convenience sampling. Standard questionnaire was used to interview 792 patient attendants (persons accompanying patients. Knowledge was computed as a continuous variable based on correct answers to fifteen questions. Multivariable linear regression was conducted to determine the factors independently associated with knowledge. Results The mean age was 38.1 (±13 years. 27.1% had received no formal education. The median knowledge score was 3.0 out of a possible maximum of 15. Only 14% were able to correctly describe CHD as a condition involving limitation in blood flow to the heart. Majority of respondents could identify only up to two risk factors for CHD. Most commonly identified risk factors were stress (43.4%, dietary fat (39.1%, smoking (31.9% and lack of exercise (17.4%. About 20% were not able to identify even a single risk factor for CHD. Factors significantly associated with knowledge included age (p = 0.023, income (p Conclusion This is the first study assessing the state of CHD knowledge in a relatively diverse non-patient population in Pakistan. There are striking gaps in knowledge about CHD, its risk factors and symptoms. These translate to inadequate preventive behavior patterns. Educational programs are urgently required to improve the level of understanding of CHD in the Pakistani population.

  16. Ethical Perspectives, Reactions to Other's Moral Behavior, and Consequent Moral Action.

    Science.gov (United States)

    Pope, William R.; Forsyth, Donelson R.

    In analyzing various moral and legal philosophies, two perspectives emerge, absolute moral rules/higher law, and situationally-specific moral rules/legal positivism. From these two perspectives, four types of individuals emerge in accordance with their degree of adherence to ideological tenets: (1) situationists (high on idealism and relativism);…

  17. Pitavastatin – a new inhibitor of the HMG-CoA reductase: peculiarities of clinical pharmacology and perspectives of its usage in treatment of cardiovascular diseases

    Directory of Open Access Journals (Sweden)

    Dzyak G.V.

    2013-12-01

    Full Text Available Cardiovascular mortality makes up 66.3 % of the total mortality in Ukraine. Myocardial infarction, stroke, atherosclerosis of peripheral arteries are the diseases caused by atherosclerosis and are prevalent in the mortality structure. One of the most effective means of successful prevention of cardiovascular disease are drugs that reduce the content of atherogenic lipids in the blood. Statins are the first line drugs for the treatment of patients with dyslipidemia and atherosclerosis in accordance with national and international guidelines. The article presents the features of the pharmacokinetics and pharmacodynamics, results of clinical trials and data on the efficacy and safety of a new inhibitor of the HMG-CoA reductase – pitavastatin (Livazo © (Recordati, Italy. Data from several multicenter randomized studies indicate that pitavastatin significantly reduces the level of cholesterol low-density lipoproteins and triglycerides, significantly increases the level of cholesterol high-density lipoproteins after 12 weeks of observation, and contributes to a significant regression of atherosclerotic plaques. It was shown that pitavastatin has a high level of safety and is well tolerated regardless of patients' age and racial origin. Pitavastatin is a new effective inhibitor of HMG -CoA reductase, which has been successfully used in many countries for the dyslipidemia treatment in patients with cardiovascular disease, diabetes, kidney diseases and other comorbid conditions.

  18. Individual differences in behavioral and cardiovascular reactivity to emotive stimuli and their relationship to cognitive flexibility in a primate model of trait anxiety.

    Directory of Open Access Journals (Sweden)

    Yoshiro Shiba

    2014-04-01

    Full Text Available High trait anxiety is a risk factor for the development of anxiety disorders. Like the disorders themselves high trait anxiety has marked phenotypic variation at the level of symptomatology and neural circuits, suggesting that there may be different symptoms and distinct neural circuits associated with risk for these disorders. To address these issues, it is essential to develop reliable animal models of trait anxiety in a non-human primate whose brain bears structural and functional similarity to humans. The present study investigated individual variation in responsivity to fearful and anxiety provoking stimuli in the common marmoset monkey. Seven out of 27 animals failed to display discriminative, conditioned cardiovascular and behavioral responses on an auditory fear discrimination task, similar to that seen in high anxious humans and rodents. Their heightened emotionality to a rubber snake was consistent with the hypothesis that they were high in trait-like anxiety. Evidence for phenotypic variation in the high anxiety group was provided by the finding that discrimination failure was predicted early in conditioning by either hyper-vigilant scanning to the cues or a reduction in blood pressure to the context, i.e. test apparatus. Given that high trait anxiety in humans can be associated with altered prefrontal cognitive functioning and previously we implicated the marmoset anterior orbitofrontal (antOFC and ventrolateral prefrontal cortex (vlPFC in negative emotion regulation, we also tested the marmosets on two tests of cognitive flexibility differentially dependent on these two regions. While the high anxious group did not differ overall in their perseverative performance, the two distinct phenotypes were differentially correlated with reduced perseverative responding on the OFC- and vlPFC-dependent flexibility tests. Together, this study provides a new model of trait anxiety in marmosets amenable to analysis of phenotypic variation and

  19. Psychological stress and cardiovascular disease

    OpenAIRE

    2002-01-01

    There is an enormous amount of literature on psychological stress and cardiovascular disease. This report reviews conceptual issues in defining stress and then explores the ramifications of stress in terms of the effects of acute versus long-term stressors on cardiac functioning. Examples of acute stressor studies are discussed in terms of disasters (earthquakes) and in the context of experimental stress physiology studies, which offer a more detailed perspective on underlying physiology. Stu...

  20. Visual Sexual Stimuli-Cue or Reward? A Perspective for Interpreting Brain Imaging Findings on Human Sexual Behaviors.

    Science.gov (United States)

    Gola, Mateusz; Wordecha, Małgorzata; Marchewka, Artur; Sescousse, Guillaume

    2016-01-01

    There is an increasing number of neuroimaging studies using visual sexual stimuli (VSS), especially within the emerging field of research on compulsive sexual behaviors (CSB). A central question in this field is whether behaviors such as excessive pornography consumption share common brain mechanisms with widely studied substance and behavioral addictions. Depending on how VSS are conceptualized, different predictions can be formulated within the frameworks of Reinforcement Learning or Incentive Salience Theory, where a crucial distinction is made between conditioned and unconditioned stimuli (related to reward anticipation vs. reward consumption, respectively). Surveying 40 recent human neuroimaging studies we show existing ambiguity about the conceptualization of VSS. Therefore, we feel that it is important to address the question of whether VSS should be considered as conditioned stimuli (cue) or unconditioned stimuli (reward). Here we present our own perspective, which is that in most laboratory settings VSS play a role of reward, as evidenced by: (1) experience of pleasure while watching VSS, possibly accompanied by genital reaction; (2) reward-related brain activity correlated with these pleasurable feelings in response to VSS; (3) a willingness to exert effort to view VSS similarly as for other rewarding stimuli such as money; and (4) conditioning for cues predictive of VSS. We hope that this perspective article will initiate a scientific discussion on this important and overlooked topic and increase attention for appropriate interpretations of results of human neuroimaging studies using VSS. PMID:27574507

  1. Visual Sexual Stimuli—Cue or Reward? A Perspective for Interpreting Brain Imaging Findings on Human Sexual Behaviors

    Science.gov (United States)

    Gola, Mateusz; Wordecha, Małgorzata; Marchewka, Artur; Sescousse, Guillaume

    2016-01-01

    There is an increasing number of neuroimaging studies using visual sexual stimuli (VSS), especially within the emerging field of research on compulsive sexual behaviors (CSB). A central question in this field is whether behaviors such as excessive pornography consumption share common brain mechanisms with widely studied substance and behavioral addictions. Depending on how VSS are conceptualized, different predictions can be formulated within the frameworks of Reinforcement Learning or Incentive Salience Theory, where a crucial distinction is made between conditioned and unconditioned stimuli (related to reward anticipation vs. reward consumption, respectively). Surveying 40 recent human neuroimaging studies we show existing ambiguity about the conceptualization of VSS. Therefore, we feel that it is important to address the question of whether VSS should be considered as conditioned stimuli (cue) or unconditioned stimuli (reward). Here we present our own perspective, which is that in most laboratory settings VSS play a role of reward, as evidenced by: (1) experience of pleasure while watching VSS, possibly accompanied by genital reaction; (2) reward-related brain activity correlated with these pleasurable feelings in response to VSS; (3) a willingness to exert effort to view VSS similarly as for other rewarding stimuli such as money; and (4) conditioning for cues predictive of VSS. We hope that this perspective article will initiate a scientific discussion on this important and overlooked topic and increase attention for appropriate interpretations of results of human neuroimaging studies using VSS. PMID:27574507

  2. Depressive Symptoms and Risk of New Cardiovascular Events or Death in Patients with Myocardial Infarction: A Population-Based Longitudinal Study Examining Health Behaviors and Health Care Interventions

    DEFF Research Database (Denmark)

    Larsen, Karen Kjær; Christensen, Bo; Søndergaard, Jens; Vestergaard, Mogens

    bruges til at skærpe opmærksomheden over for denne patientgruppe hos de praktiserende læger, hvor op mod 90 % af alle patienter med depression bliver diagnosticeret og behandlet. Background: Depressive symptoms is associated with adverse cardiovascular outcomes in patients with myocardial infarction (MI......), but the underlying mechanisms are unclear and it remains unknown whether subgroups of patients are at a particularly high relative risk of adverse outcomes. We examined the risk of new cardiovascular events and/or death in patients with depressive symptoms following first-time MI taking into account...... 2009 and 31 December 2009, and followed up until 31 July 2012. Depressive symptoms were found in 18.6% using the Hospital Anxiety and Depression Scale (HADS-D$8). A total of 239 new cardiovascular events, 95 deaths, and 288 composite events (239 new cardiovascular events and 49 deaths) occurred during...

  3. Evolutionary and neuropsychological perspectives on addictive behaviors and addictive substances: relevance to the “food addiction” construct

    OpenAIRE

    Davis, Caroline

    2014-01-01

    It has been argued that food cannot be “addictive”, unlike conventional drugs of abuse, because it is an essential part of life. In this paper, evidence is reviewed, largely from an evolutionary psychobiological perspective, that plant-based psychoactive drugs (such as those derived from the opium poppy and the coca leaf) and gambling-related behaviors were once adaptive for human health and survival in a similar manner as energy-based foods were for nourishment. “Evolutionary mismatch” viewp...

  4. Turning Visitors into Customers: A Usability-Centric Perspective on Purchase Behavior in Electronic Channels

    OpenAIRE

    Viswanath Venkatesh; Ritu Agarwal

    2006-01-01

    We develop a theoretical model for predicting purchase behavior in electronic channels. The model suggests that website use (i.e., technology use), a key indicator of the degree to which a site is "sticky," is a significant antecedent of purchase behavior. Furthermore, we relate the usability of a website to use behavior and purchase behavior. Specifically, individual characteristics and product type are argued to differentially influence the weights that customers place on five different cat...

  5. Disturbing, Disordered or Disturbed? Perspectives on the Definition of Problem Behavior in Educational Settings.

    Science.gov (United States)

    Wood, Frank H., Ed.; Lakin, K. Charlie, Ed.

    The book contains five papers presented at a 1979 topical conference on the definition of emotional disturbance and behavioral disorders in educational settings. The first paper, by F. Wood, is titled "Defining Disturbing, Disordered, and Disturbed Behavior." Topics covered include ambivalence about defining deviant behavior by special educators,…

  6. Hierarchically Organized Behavior and Its Neural Foundations: A Reinforcement Learning Perspective

    Science.gov (United States)

    Botvinick, Matthew M.; Niv, Yael; Barto, Andrew C.

    2009-01-01

    Research on human and animal behavior has long emphasized its hierarchical structure--the divisibility of ongoing behavior into discrete tasks, which are comprised of subtask sequences, which in turn are built of simple actions. The hierarchical structure of behavior has also been of enduring interest within neuroscience, where it has been widely…

  7. Parent and Teacher Perspectives about Problem Behavior in Children with Williams Syndrome

    Science.gov (United States)

    Klein-Tasman, Bonita P.; Lira, Ernesto N.; Li-Barber, Kirsten T.; Gallo, Frank J.; Brei, Natalie G.

    2015-01-01

    Problem behavior of 52 children with Williams syndrome ages 6 to 17 years old was examined based on both parent and teacher report. Generally good inter-rater agreement was found. Common areas of problem behavior based both on parent and teacher report included attention problems, anxiety difficulties, repetitive behaviors (e.g., obsessions,…

  8. Incremental Validity and Informant Effect from a Multi-Method Perspective: Assessing Relations between Parental Acceptance and Children's Behavioral Problems.

    Science.gov (United States)

    Izquierdo-Sotorrío, Eva; Holgado-Tello, Francisco P; Carrasco, Miguel Á

    2016-01-01

    This study examines the relationships between perceived parental acceptance and children's behavioral problems (externalizing and internalizing) from a multi-informant perspective. Using mothers, fathers, and children as sources of information, we explore the informant effect and incremental validity. The sample was composed of 681 participants (227 children, 227 fathers, and 227 mothers). Children's (40% boys) ages ranged from 9 to 17 years (M = 12.52, SD = 1.81). Parents and children completed both the Parental Acceptance Rejection/Control Questionnaire (PARQ/Control) and the check list of the Achenbach System of Empirically Based Assessment (ASEBA). Statistical analyses were based on the correlated uniqueness multitrait-multimethod matrix (model MTMM) by structural equations and different hierarchical regression analyses. Results showed a significant informant effect and a different incremental validity related to which combination of sources was considered. A multi-informant perspective rather than a single one increased the predictive value. Our results suggest that mother-father or child-father combinations seem to be the best way to optimize the multi-informant method in order to predict children's behavioral problems based on perceived parental acceptance. PMID:27242582

  9. Cardiovascular group

    Science.gov (United States)

    Blomqvist, Gunnar

    1989-01-01

    As a starting point, the group defined a primary goal of maintaining in flight a level of systemic oxygen transport capacity comparable to each individual's preflight upright baseline. The goal of maintaining capacity at preflight levels would seem to be a reasonable objective for several different reasons, including the maintenance of good health in general and the preservation of sufficient cardiovascular reserve capacity to meet operational demands. It is also important not to introduce confounding variables in whatever other physiological studies are being performed. A change in the level of fitness is likely to be a significant confounding variable in the study of many organ systems. The principal component of the in-flight cardiovascular exercise program should be large-muscle activity such as treadmill exercise. It is desirable that at least one session per week be monitored to assure maintenance of proper functional levels and to provide guidance for any adjustments of the exercise prescription. Appropriate measurements include evaluation of the heart-rate/workload or the heart-rate/oxygen-uptake relationship. Respiratory gas analysis is helpful by providing better opportunities to document relative workload levels from analysis of the interrelationships among VO2, VCO2, and ventilation. The committee felt that there is no clear evidence that any particular in-flight exercise regimen is protective against orthostatic hypotension during the early readaptation phase. Some group members suggested that maintenance of the lower body muscle mass and muscle tone may be helpful. There is also evidence that late in-flight interventions to reexpand blood volume to preflight levels are helpful in preventing or minimizing postflight orthostatic hypotension.

  10. Oxytocin Receptor (OXTR) Single Nucleotide Polymorphisms Indirectly Predict Prosocial Behavior Through Perspective Taking and Empathic Concern.

    Science.gov (United States)

    Christ, Christa C; Carlo, Gustavo; Stoltenberg, Scott F

    2016-04-01

    Engaging in prosocial behavior can provide positive outcomes for self and others. Prosocial tendencies contribute to the propensity to engage in prosocial behavior. The oxytocin receptor gene (OXTR) has also been associated with prosocial tendencies and behaviors. There has been little research, however, investigating whether the relationship between OXTR and prosocial behaviors is mediated by prosocial tendencies. This relationship may also vary among different types of prosocial behavior. The current study examines the relationship between OXTR, gender, prosocial tendencies, and both altruistic and public prosocial behavior endorsement. Students at a midwestern university (N = 398; 89.2% Caucasian; Mage  = 20.76; 26.6% male) provided self-report measures of prosocial tendencies and behaviors and buccal cells for genotyping OXTR polymorphisms. Results indicated that OXTR single nucleotide polymorphism (SNP) rs2268498 genotype significantly predicted empathic concern, whereas gender moderated the association between several other OXTR SNPs and prosocial tendencies. Increased prosocial tendencies predicted increased altruistic prosocial behavior endorsement and decreased public prosocial behavior endorsement. Our findings suggest an association between genetic variation in OXTR and endorsement of prosocial behavior indirectly through prosocial tendencies, and that the pathway is dependent on the type of prosocial behavior and gender. PMID:25403479

  11. A Qualitative Study Exploring Facilitators for Improved Health Behaviors and Health Behavior Programs: Mental Health Service Users’ Perspectives

    Directory of Open Access Journals (Sweden)

    Candida Graham

    2014-01-01

    Full Text Available Objective. Mental health service users experience high rates of cardiometabolic disorders and have a 20–25% shorter life expectancy than the general population from such disorders. Clinician-led health behavior programs have shown moderate improvements, for mental health service users, in managing aspects of cardiometabolic disorders. This study sought to potentially enhance health initiatives by exploring (1 facilitators that help mental health service users engage in better health behaviors and (2 the types of health programs mental health service users want to develop. Methods. A qualitative study utilizing focus groups was conducted with 37 mental health service users attending a psychosocial rehabilitation center, in Northern British Columbia, Canada. Results. Four major facilitator themes were identified: (1 factors of empowerment, self-value, and personal growth; (2 the need for social support; (3 pragmatic aspects of motivation and planning; and (4 access. Participants believed that engaging with programs of physical activity, nutrition, creativity, and illness support would motivate them to live more healthily. Conclusions and Implications for Practice. Being able to contribute to health behavior programs, feeling valued and able to experience personal growth are vital factors to engage mental health service users in health programs. Clinicians and health care policy makers need to account for these considerations to improve success of health improvement initiatives for this population.

  12. Behavioral scripts of urban park offenders : a rational choice perspective on influences of the park setting

    OpenAIRE

    Michael, Sean Edward

    1997-01-01

    This study examined the influence of Iocational factors on offender behavior in four serious and common park offenses: auto burglary, drug sales, indecent exposure by homosexual males, and robbery. Specifically, the study sought 1) to develop prototypical script(s) for each of the four study crimes, and 2) to support or contradict the influence of effort, risk and reward on offender behavior. Using the theoretical bases of opportunity, rational choice, and scripts, behavior of ...

  13. Violent Video Games and Delinquent Behavior in Adolescents: a Risk Factor Perspective

    OpenAIRE

    Exelmans, Liese; Custers, Kathleen; Van den Bulck, Jan

    2015-01-01

    Over the years, criminological research has identified a number of risk factors that contribute to the development of aggressive and delinquent behavior. Although studies have identified media violence in general and violent video gaming in particular as significant predictors of aggressive behavior, exposure to violent video games has been largely omitted from the risk factor literature on delinquent behavior. This cross-sectional study therefore investigates the relationship between viole...

  14. A Behavioral Theory Perspective on Acquisitions, Acquisition Performance, and Strategic Alternatives

    OpenAIRE

    Kuusela, Pasi

    2013-01-01

    Attention and performance aspirations are two focal concepts of the behavioral theory of the firm (BTOF), and extensive prior research has examined their role as antecedents of firm behavior. The effects of aspirations and attention on the relationship between firm behavior and performance outcomes are substantially less well understood. To address this gap, I study the performance implications of attention and performance relative to aspirations in the context of serial acquisitions. This di...

  15. An evolutionary perspective on the behavioral consequences of exogenous oxytocin application.

    Directory of Open Access Journals (Sweden)

    R Becket Ebitz

    2014-01-01

    Full Text Available Oxytocin (OT is released in response to social signals, particularly positive ones like eye contact, social touch, sexual behavior, and affiliative vocalizations. Conversely, exogenous delivery of OT has diverse behavioral effects, sometimes promoting affiliative and prosocial behaviors, but sometimes suppressing them. Here, we argue that one unifying interpretation of these diverse effects is to view OT as an evolutionarily conserved physiological signal indicating affiliative interactions and predicting their behavioral consequences. In this model, OT regulates the way information about the social environment accesses the neural circuitry responsible for social behavior, thereby shaping it in sometimes counterintuitive but adaptive ways. Notably, prosociality is not always the most adaptive response to an affiliative signal from another individual. In many circumstances, an asocial or even antisocial response may confer greater fitness benefits. We argue that the behavioral effects of exogenous OT delivery not only parallel the behavioral effects of affiliative interactions, but are themselves adaptive responses to affiliative interactions. In support of this idea, we review recent evidence that OT does not unilaterally enhance social attention, as previously thought, but often reduces the salience of social signals in the environment. Such diminished social vigilance may be an adaptive response to affiliative social interactions because it frees attentional resources for the pursuit of other goals. Finally, we predict that OT may mediate other behavioral consequences of social interactions, such as reduced predator vigilance, and argue that this is a rich avenue for future behavioral and neurobiological study.

  16. An evolutionary perspective on the behavioral consequences of exogenous oxytocin application

    Science.gov (United States)

    Ebitz, R. Becket; Platt, Michael L.

    2014-01-01

    Oxytocin (OT) is released in response to social signals, particularly positive ones like eye contact, social touch, sexual behavior, and affiliative vocalizations. Conversely, exogenous delivery of OT has diverse behavioral effects, sometimes promoting affiliative and prosocial behaviors, but sometimes suppressing them. Here, we argue that one unifying interpretation of these diverse effects is to view OT as an evolutionarily conserved physiological signal indicating affiliative interactions and predicting their behavioral consequences. In this model, OT regulates the way information about the social environment accesses the neural circuitry responsible for social behavior, thereby shaping it in sometimes counter intuitive but adaptive ways. Notably, prosociality is not always the most adaptive response to an affiliative signal from another individual. In many circumstances, an asocial or even antisocial response may confer greater fitness benefits. We argue that the behavioral effects of exogenous OT delivery not only parallel the behavioral effects of affiliative interactions, but are themselves adaptive responses to affiliative interactions. In support of this idea, we review recent evidence that OT does not unilaterally enhance social attention, as previously thought, but rather can reduce the typical prioritization of social information at the expense of other information or goals. Such diminished social vigilance may be an adaptive response to affiliative social interactions because it frees attentional resources for the pursuit of other goals. Finally, we predict that OT may mediate other behavioral consequences of social interactions, such as reduced predator vigilance, and argue that this is a rich avenue for future behavioral and neurobiological study. PMID:24478646

  17. New perspectives in the renin-angiotensin-aldosterone system (RAAS III: endogenous inhibition of angiotensin converting enzyme (ACE provides protection against cardiovascular diseases.

    Directory of Open Access Journals (Sweden)

    Miklós Fagyas

    Full Text Available ACE inhibitor drugs decrease mortality by up to one-fifth in cardiovascular patients. Surprisingly, there are reports dating back to 1979 suggesting the existence of endogenous ACE inhibitors. Here we investigated the clinical significance of this potential endogenous ACE inhibition. ACE concentration and activity was measured in patient's serum samples (n = 151. ACE concentration was found to be in a wide range (47-288 ng/mL. ACE activity decreased with the increasing concentration of the serum albumin (HSA: ACE activity was 56 ± 1 U/L in the presence of 2.4 ± 0.3 mg/mL HSA, compared to 39 ± 1 U/L in the presence of 12 ± 1 mg/mL HSA (values are mean ± SEM. Effects of the differences in ACE concentration were suppressed in human sera: patients with ACE DD genotype exhibited a 64% higher serum ACE concentration (range, 74-288 ng/mL, median, 155.2 ng/mL, n = 52 compared to patients with II genotype (range, 47-194 ng/mL, median, 94.5 ng/mL, n = 28 while the difference in ACE activities was only 32% (range, 27.3-59.8 U/L, median, 43.11 U/L, and range 15.6-55.4 U/L, median, 32.74 U/L, respectively in the presence of 12 ± 1 mg/mL HSA. No correlations were found between serum ACE concentration (or genotype and cardiovascular diseases, in accordance with the proposed suppressed physiological ACE activities by HSA (concentration in the sera of these patients: 48.5 ± 0.5 mg/mL or other endogenous inhibitors. Main implications are that (1 physiological ACE activity can be stabilized at a low level by endogenous ACE inhibitors, such as HSA; (2 angiotensin II elimination may have a significant role in angiotensin II related pathologies.

  18. To talk or not to talk: reflections on Central Bank communication from a behavioral perspective

    OpenAIRE

    Comanescu, Anton Constantin

    2010-01-01

    The paper investigates the role of central bank communication for monetary policy implementation. Firstly, we use a multi-disciplinary approach to disentangle several problematic contingencies of central bank communication, analyzing from this perspective the role of complex phenomena such as public opinion, perceptions, beliefs, framing, subjective probability, rhetoric, persuasion, cognitive limits and distortions, psychological and cultural biases etc. The result is a comprehensive survey ...

  19. A Mind-Reader Does Not Always Have Deontological Moral Judgments and Prosocial Behavior: A Developmental Perspective.

    Science.gov (United States)

    Hao, Jian; Liu, Yanchun

    2016-01-01

    of mind may be a permanent tool for moral judgment development but a temporary tool for prosocial behavior development. Thus, the present study enriches the rationalistic theories of morality from a developmental perspective. Different relationships between theory of mind and morality from middle childhood to late adulthood are discussed. PMID:27602011

  20. Repetitive Behaviors in Autism and Obsessive-Compulsive Disorder: New Perspectives from a Network Analysis

    Science.gov (United States)

    Ruzzano, Laura; Borsboom, Denny; Geurts, Hilde M.

    2015-01-01

    The association between autism and obsessive-compulsive disorder (OCD) seems largely dependent upon observed similarities in the repetitive behaviors that manifest in both disorders. The aim of this study was to use a network approach to explore the interactions between these behaviors. We constructed a network based on clinician's…

  1. The Role of the Pediatric Cerebellum in Motor Functions, Cognition, and Behavior: A Clinical Perspective.

    Science.gov (United States)

    Salman, Michael S; Tsai, Peter

    2016-08-01

    This article discusses the contribution of the pediatric cerebellum to locomotion, ocular motor control, speech articulation, cognitive function, and behavior modulation. Hypotheses on cerebellar function are discussed. Clinical features in patients with cerebellar disorders are outlined. Cerebellar abnormalities in cognitive and behavioral disorders are detailed. PMID:27423796

  2. Impact of Student Behavior on a School Culture from the Teacher's Perspective

    Science.gov (United States)

    Shell, Tiehise E.

    2010-01-01

    The impact of student behavior on the school culture from the teachers' perceptive was determined in this study. Through an awareness of the impact that student behavior has on the school culture, school administrators can alter the negative effects and implement positive change. The participants included 25 randomly chosen teachers from within…

  3. Staff Perspectives of Precipitants to Aggressive Behavior of Adolescents in Residential Treatment Facilities

    Science.gov (United States)

    dosReis, Susan; Davarya, Sarah

    2008-01-01

    Face-to-face, semistructured interviews with 18 staff in a public psychiatric adolescent residential treatment facility were conducted to obtain an inductive approach to their understanding of what leads to aggressive behavior among adolescents. Staff's views of the precipitants of aggressive behavior centered on three themes: understanding of the…

  4. Of mice and marbles: Novel perspectives on burying behavior as a screening test for psychiatric illness.

    Science.gov (United States)

    Wolmarans, De Wet; Stein, Dan J; Harvey, Brian H

    2016-06-01

    Burying forms part of the normal behavioral routine of rodents, although its expression is species-specific. However, it has been suggested that aberrant burying behavior, of which marble-burying (MB) is an example, may represent neophobic and/or compulsive-like behavior. In the present investigation, we assessed MB in an established animal model of obsessive-compulsive disorder (OCD)-namely, spontaneous stereotypy in the deer mouse-to establish whether high (H) stereotypy is associated with neophobia and/or another compulsive endophenotype, i.e. MB, as compared to nonstereotypical (N) controls. A three-trial, one-zone MB test was performed over three consecutive evenings both before and after chronic treatment with high-dose (50 mg/kg/day) oral escitalopram. Neophobia was measured via the number of marbles buried during the first pre- and posttreatment MB trials, and compulsive-like behavior via the number of marbles buried over all pre- and posttreatment MB trials. The data from the present study support earlier findings that burying is a normal behavioral routine (inherent burying behavior, IBB) that is expressed by all deer mice, irrespective of stereotypical cohort, and is not associated with either neophobia or compulsiveness. Indeed, chronic escitalopram treatment, which is similarly effective in treating clinical anxiety and OCD, as well as in attenuating H behavior, failed to influence IBB. Although 11 % of the animals presented with a unique burying endophenotype (high burying behavior), escitalopram also failed to attenuate said behavior, necessitating further investigation as to its relevance. In conclusion, MB cannot be regarded as a measure of anxiety-like or compulsive behavior in the deer mouse model of OCD. PMID:26920212

  5. The Influences of Perceived Factors on Consumer Purchasing Behavior: In the Perspective of Online Shopping Capability of Consumers

    Directory of Open Access Journals (Sweden)

    Yingcong Xu

    2013-05-01

    Full Text Available In this study, firstly, based on related researches about consumer online purchasing behavior before, we proposed that there were some perceived factors that influence perceived value which has a direct impact on consumer’s online purchasing decision-making. Secondly, on the analysis for the antecedent of consumer perceived factors with online shopping, we proposed the definition of online shopping capability of consumer and try to explore what factors would affect consumers’ perceived value when they are online shopping in the perspective of consumer’s online shopping capability and their different influences on consumer purchasing behavior. We designed a questionnaire and obtained 1359 valid data from our investigation. Data analysis indicates that besides online shopping capability of consumers, there are other four significant common factors such as trust, perceived risk, perceived benefit and perceived cost, have significant influences on consumers’ perceived value. The causal relation among online shopping capability of consumers, the other four perceived factors and perceived value and consumer online purchasing behavior are verified using confirmatory factor analysis. We explored the differences and their changing way among different kinds of consumers. Discussions for the results indicated that consumers with different shopping experiences have different online shopping capabilities and significant differences on the other four perceived factors.

  6. Relationship of Corporate Social Responsibility with Consumer Buying Behavior: An Indian Perspective

    Directory of Open Access Journals (Sweden)

    Supran Kumar Sharma

    2013-12-01

    Full Text Available With the help of binary logistic regression model present attempt examines the impact of business organization’s Corporate Social Responsibility (CSR practices on buying behavior of the consumers. By taking the responses of 197 consumers in the Jammu and Kashmir province of India, the study highlights that how different dimensions of CSR practices and selected demographics of the organizations are significantly associated with the buying behavior of consumers. The study finds negative relationship between both legal responsibilities and environment friendly practices of companies with the consumer buying behavior. The results have implications for marketing practitioners and strategic management professionals who would like to use their organisation’s CSR practices as a tool to positively influence consumer behavior. Findings suggest that business organizations should be more transparent on their legal aspects and philanthropic activities.

  7. Financial Decision-Making in Markets and Firms: A Behavioral Perspective

    OpenAIRE

    Bondt, Werner F.M. de; Thaler, Richard H.

    1994-01-01

    In its attempt to model financial markets and the behavior of firms, modern finance theory starts from a set of normatively appealing axioms about individual behavior. Specifically, people are said to be risk-averse expected utility maximizers and unbiased Bayesian forecasters, i.e., agents make rational choices based on rational expectations. The rational paradigm may be criticized, however, because (1) the assumptions are descriptively false and incomplete, and (2) the theory often lacks pr...

  8. Perceived Usefulness and Trust towards Consumer Behaviors: A Perspective of Consumer Online Shopping

    OpenAIRE

    Lim Yi Jin; Abdullah Bin Osman; Mohd Suberi Bin AB.Halim

    2014-01-01

    In this globalization era, the Internet has become an important tool for web browsing, social networking and even making online purchases. In Malaysia, few studies have examined the influence of perceived usefulness and trust on the online shopping behavior of consumers. Thus, the current study intends to investigate whether perceived usefulness and trust influence the online shopping behavior of consumers in northern Malaysia which comprises Kedah, Perlis, Penang and Perak. The relationship ...

  9. Relationship of Corporate Social Responsibility with Consumer Buying Behavior: An Indian Perspective

    OpenAIRE

    Supran Kumar Sharma; Shravani Sharma

    2013-01-01

    With the help of binary logistic regression model present attempt examines the impact of business organization’s Corporate Social Responsibility (CSR) practices on buying behavior of the consumers. By taking the responses of 197 consumers in the Jammu and Kashmir province of India, the study highlights that how different dimensions of CSR practices and selected demographics of the organizations are significantly associated with the buying behavior of consumers. The study finds negative relati...

  10. Self care behavior among patients with diabetes in Harari, Eastern Ethiopia: the health belief model perspective

    OpenAIRE

    Ketema Ayele; Bisrat Tesfa; Lakew Abebe; Tizta Tilahun; Eshetu Girma

    2012-01-01

    Background: Diabetes mellitus is a chronic disease that requires lifelong medical treatments and a life style adjustment. To prevent serious morbidity and mortality, it requires dedication to demanding self-care behaviors in multiple domains. The objective of this study was to identify predictors of self care behaviors among patients with diabetes. Methods: From a total of 425 follow up diabetic patients, a quantitative cross sectional study was conducted among 222 of them from three diffe...

  11. Assessing student collaboration and learning in medical engineering from the perspectives of structures, behaviors, and function

    OpenAIRE

    Chan, CKK; Chan, YY; Yu, ACH

    2010-01-01

    Learning in biomedical engineering is highly interdisciplinary: students need to integrate concepts between engineering and life sciences, and be able to design and develop technologies with physiological considerations. In this study, biomedical engineering students’ artifacts were analyzed in detail according to the structure-behavior-framework (SBF) framework. The SBF framework has been investigated by educational researchers and learning scientists; in particular, the behavioral and fu...

  12. PREDICTORS OF EMOTIONAL AND BEHAVIORAL PROBLEMS IN 1-YEAR-OLD CHILDREN: A LONGITUDINAL PERSPECTIVE.

    Science.gov (United States)

    Sirvinskiene, Giedre; Zemaitiene, Nida; Jusiene, Roma; Markuniene, Egle

    2016-07-01

    Emotional and behavioral problems at an early age can reasonably be considered a high-risk factor for later mental health disorders. The aim of the article is to reveal predictive factors of 1½-year-old children's emotional and behavioral problems. The study was a part of a prospective birth-cohort study. The study sample consisted of 172 full-term infants (born during Gestational Weeks 37-42) and their mothers. Emotional and behavioral problems at the age of 1½ years were measured using the Child Behavior Checklist for Ages 1½-5 (T. Achenbach & L. Rescorla, 2000), which was completed by mothers. Emotional and behavioral problems at age of 1½ years were more prevalent in infants born via cesarean section, as compared to infants born vaginally without administration of medication. Newborns' suboptimal functioning after birth, complicated emotional acceptance of pregnancy, a couple's nonsatisfactory relationship during pregnancy, maternal distress during pregnancy and in the first months after childbirth, and inflexible and parent-oriented attitudes toward infant-rearing also predicted children's emotional and behavioral problems independent of sociodemographic factors. Results suggest that biomedical and psychosocial factors which manifest themselves in the prenatal and perinatal periods can have associations with later infant and child mental health. PMID:27336695

  13. Inhibition and Encouragement of Entrepreneurial Behavior: Antecedents Analysis from Managers’ Perspectives

    Directory of Open Access Journals (Sweden)

    Marcos Hashimoto

    2014-10-01

    Full Text Available One of the paths chosen by businesses to increase their competitiveness through innovation is by encouraging employees to adopt a more entrepreneurial attitude. Although studies on Entrepreneurial Orientation have brought important contributions, anecdotal evidences of entrepreneurial employees not affected by corporate initiatives drive attention to managers’ roles in developing entrepreneurial behavior. We found good possible explanations in the theory Induced vs. Autonomous Entrepreneurial Behavior. Thus, the objective of this study is to empirically analyze the factors that inhibit or encourage entrepreneurial behavior. These factors arose from empirical research and were consolidated based on a literature review. This is a qualitative study whose data were collected in interviews carried out with 15 executives from different businesses in Brazil. The results showed that, while some Entrepreneurially Oriented practices can induce employees to adopt entrepreneurial behavior, autonomous behavior intrapreneurs are mostly stimulated by manager attitude. Managers use different approaches depending on the type of intrapreneur whose entrepreneurial behavior is intended to be stimulated, leading to the conclusion that managers, in some cases, play an important role in promoting Corporate Entrepreneurship.

  14. Violent video games and delinquent behavior in adolescents: A risk factor perspective.

    Science.gov (United States)

    Exelmans, Liese; Custers, Kathleen; Van den Bulck, Jan

    2015-05-01

    Over the years, criminological research has identified a number of risk factors that contribute to the development of aggressive and delinquent behavior. Although studies have identified media violence in general and violent video gaming in particular as significant predictors of aggressive behavior, exposure to violent video games has been largely omitted from the risk factor literature on delinquent behavior. This cross-sectional study therefore investigates the relationship between violent video game play and adolescents' delinquent behavior using a risk factor approach. An online survey was completed by 3,372 Flemish adolescents, aged 12-18 years old. Data were analyzed by means of negative binomial regression modelling. Results indicated a significant contribution of violent video games in delinquent behavior over and beyond multiple known risk variables (peer delinquency, sensation seeking, prior victimization, and alienation). Moreover, the final model that incorporated the gaming genres proved to be significantly better than the model without the gaming genres. Results provided support for a cumulative and multiplicative risk model for delinquent behavior. Aggr. Behav. 41:267-279, 2015. © 2015 Wiley Periodicals, Inc. PMID:25732796

  15. Does temporal discounting explain unhealthy behavior? A systematic review and reinforcement learning perspective

    Directory of Open Access Journals (Sweden)

    Giles eStory

    2014-03-01

    Full Text Available The tendency to make unhealthy choices is hypothesized to be related to an individual's temporal discount rate, the theoretical rate at which they devalue delayed rewards. Furthermore, a particular form of temporal discounting, hyperbolic discounting, has been proposed to explain why unhealthy behavior can occur despite healthy intentions. We examine these two hypotheses in turn. We first systematically review studies which investigate whether discount rates can predict unhealthy behavior. These studies reveal that high discount rates for money (and in some instances food or drug rewards are associated with several unhealthy behaviors and markers of health status, establishing discounting as a promising predictive measure. We secondly examine whether intention-incongruent unhealthy actions are consistent with hyperbolic discounting. We conclude that intention-incongruent actions are often triggered by environmental cues or changes in motivational state, whose effects are not parameterized by hyperbolic discounting. We propose a framework for understanding these state-based effects in terms of the interplay of two distinct reinforcement learning mechanisms: a model-based (or goal-directed system and a model-free (or habitual system. Under this framework, while discounting of delayed health may contribute to the initiation of unhealthy behavior, with repetition, many unhealthy behaviors become habitual; if health goals then change, habitual behavior can still arise in response to environmental cues. We propose that the burgeoning development of computational models of these processes will permit further identification of health decision-making phenotypes.

  16. "Economic man" in cross-cultural perspective: behavioral experiments in 15 small-scale societies.

    Science.gov (United States)

    Henrich, Joseph; Boyd, Robert; Bowles, Samuel; Camerer, Colin; Fehr, Ernst; Gintis, Herbert; McElreath, Richard; Alvard, Michael; Barr, Abigail; Ensminger, Jean; Henrich, Natalie Smith; Hill, Kim; Gil-White, Francisco; Gurven, Michael; Marlowe, Frank W; Patton, John Q; Tracer, David

    2005-12-01

    Researchers from across the social sciences have found consistent deviations from the predictions of the canonical model of self-interest in hundreds of experiments from around the world. This research, however, cannot determine whether the uniformity results from universal patterns of human behavior or from the limited cultural variation available among the university students used in virtually all prior experimental work. To address this, we undertook a cross-cultural study of behavior in ultimatum, public goods, and dictator games in a range of small-scale societies exhibiting a wide variety of economic and cultural conditions. We found, first, that the canonical model - based on self-interest - fails in all of the societies studied. Second, our data reveal substantially more behavioral variability across social groups than has been found in previous research. Third, group-level differences in economic organization and the structure of social interactions explain a substantial portion of the behavioral variation across societies: the higher the degree of market integration and the higher the payoffs to cooperation in everyday life, the greater the level of prosociality expressed in experimental games. Fourth, the available individual-level economic and demographic variables do not consistently explain game behavior, either within or across groups. Fifth, in many cases experimental play appears to reflect the common interactional patterns of everyday life. PMID:16372952

  17. The role of proactive personality in job satisfaction and organizational citizenship behavior: a relational perspective.

    Science.gov (United States)

    Li, Ning; Liang, Jian; Crant, J Michael

    2010-03-01

    Drawing from a relational approach, the authors conceptualize the quality of leader-member exchange as a mediator and procedural justice climate as a contextual moderator for understanding the role of proactive personality in job satisfaction and organizational citizenship behavior. Data from a sample of 200 Chinese employees within 54 work groups were used to examine the hypothesized models. Results show that having a proactive personality was associated with employees establishing a high-quality exchange relationship with their supervisors; in turn, the quality of leader-member exchange was associated with greater job satisfaction and more organizational citizenship behaviors. Additionally, the relationship between proactive personality and organizational citizenship behavior was positively moderated by procedural justice climate within the group. Implications for management theory and practice are discussed. PMID:20230079

  18. Health behavior change benefits: Perspectives of Latinos with serious mental illness.

    Science.gov (United States)

    Jimenez, Daniel E; Burrows, Kimberly; Aschbrenner, Kelly; Barre, Laura K; Pratt, Sarah I; Alegría, Margarita; Bartels, Stephen J

    2016-06-01

    The objective of this study was to explore the perceived benefits of engaging in health behavior change from the viewpoint of overweight and obese Latinos with severe mental illness (SMI) enrolled in the U.S. Qualitative, semistructured interviews were conducted with 20 obese Latinos with SMI who were enrolled in a randomized trial evaluating the effectiveness of a motivational health promotion intervention adapted for persons with SMI. Overweight and obese Latino participants believed that engaging in health behavior change would have both physical and mental health benefits, including chronic disease management, changes in weight and body composition, and increased self-esteem. Interventions that explicitly link physical activity and healthy eating to improvements in mental health and well-being may motivate Latinos with SMI to adopt health behavior change. PMID:26873582

  19. Youth, Caregiver, and Staff Perspectives on an Initiative to Promote Success of Emerging Adults with Emotional and Behavioral Disabilities.

    Science.gov (United States)

    Stein, Kathleen F; Connors, Elizabeth H; Chambers, Kerri L; Thomas, Charmaine L; Stephan, Sharon H

    2014-07-01

    Transitioning to adulthood is more challenging for youth with emotional and behavioral disorders (EBD) as compared to youth with other disability types and typically-developing peers. Outcomes for emerging adults with EBD as a group are particularly concerning in the domains of unemployment, educational dropout rates, and interactions with the judicial system including incarceration, early parenting, homelessness, substance abuse, mental health problems, and suicide. The current study presents qualitative program evaluation data for one of seven grantee states awarded 5-year cooperative agreements by the Substance Abuse Mental Health Services Administration (SAMHSA) to build developmentally-appropriate and effective youth-guided local systems of care for transition age youth, ages 16-25 years, to promote positive transition outcomes. Findings, obtained from focus groups of 25 participating transition age youth, caregivers, staff, and supervisors, include strategies for maintaining and expanding on the strengths of program, as well as for improving specific program areas. Also, consistent with the goals of the program, this process provided an opportunity for the youth and caregivers to voice their opinions and perspectives regarding their services. Implications for research and practice on effectively serving the unique needs of young adults experiencing EBD and their families in areas such as navigating special education, providing emotional and behavioral supports, and leveraging interagency collaboration are discussed. PMID:25005428

  20. Supervisory Coaching Behavior, Employee Satisfaction, and Warehouse Employee Performance: A Dyadic Perspective in the Distribution Industry

    Science.gov (United States)

    Ellinger, Andrea D.; Ellinger, Alexander E.; Keller, Scott B.

    2003-01-01

    Coaching has received considerable attention in recent years as the responsibility for employees' learning and development has been increasingly devolved to line managers. Yet there exists little published empirical research that measures specific coaching behaviors of line managers or examines the linkages between line managers' coaching behavior…

  1. Marijuana Experiences, Voting Behaviors, and Early Perspectives Regarding Marijuana Legalization among College Students from 2 States

    Science.gov (United States)

    Moreno, Megan A.; Whitehill, Jennifer M.; Quach, Vincent; Midamba, Nikita; Manskopf, Inga

    2016-01-01

    Objective: The purpose of this mixed-methods study was to understand college students' (1) views and experiences regarding marijuana, (2) voting behaviors, and (3) early perceptions of the impact of legislation. Participants: College students from Washington and Wisconsin were interviewed between May and September 2013. Methods: Participants…

  2. Media violence and children’s ADHD-related behaviors: a genetic susceptibility perspective

    NARCIS (Netherlands)

    S.W.C. Nikkelen; H.G.M. Vossen; P.M. Valkenburg; F.P. Velders; D.A. Windhorst; V.W.V. Jaddoe; A. Hofman; F.C. Verhulst; H. Tiemeier

    2014-01-01

    This study examined the relationship between media violence exposure and Attention-deficit/hyperactivity disorder (ADHD)-related behaviors. Using survey (parent-reported) and genetic data of 1,612 Dutch children (aged 5 to 9 years), we examined genetic disposition as a possible cause of individual d

  3. Cleavage-based voting behavior in cross-national perspective : Evidence from six postwar democracies

    NARCIS (Netherlands)

    Brooks, Clem; Nieuwbeerta, Paul; Manza, Jeff

    2006-01-01

    We investigate trends and cross-national variation in the impact of class, religious, and gender cleavages on voting behavior in six advanced capitalist democracies in the postwar period. Earlier research on cleavage voting has been criticized for utilizing outdated ‘‘two-class’’ models of class str

  4. Cleavage-based voting behavior in cross-national perspective: evidence from six postwar democracies

    NARCIS (Netherlands)

    Brooks, Clem; Nieuwbeerta, Paul; Manza, Jeff

    2006-01-01

    We investigate trends and cross-national variation in the impact of class, religious, and gender cleavages on voting behavior in six advanced capitalist democracies in the postwar period. Earlier research on cleavage voting has been criticized for utilizing outdated “two-class” models of class struc

  5. Temporal perspective on individual driver behavior using electronic records of undesirable events.

    Science.gov (United States)

    Musicant, Oren; Bar-Gera, Hillel; Schechtman, Edna

    2014-09-01

    This paper explores In-Vehicle Data Recorders (IVDRs) information about the count of undesirable driving events (such as hard braking, lane changing, and sharp turning) of 148 individuals. The information was logged over three years and included time stamp information about the occurrence of undesirable driving events in each trip (N=573,238). The objective was to gain deeper understanding about the heterogeneity among drivers with respect to behavior change over time, the effect of trip duration and the distribution of events count. Our findings show that in some respects drivers are similar: for all drivers, the variance of the events count was larger than the mean, indicating that the negative binomial distribution is suitable to model the distribution of events count per trip. Most drivers (95%) had lower events rate during longer trips, suggesting that a 'simple' events rate index is problematic when comparing between those driving longer trips and drivers driving short trips. In addition, most drivers (87%) improved their driving behavior throughout the measurement period. However, there are important differences among drivers in terms of the frequency of behavior change and the trends in behavior over time. These findings demonstrate the need for personalized examination of individual drivers. Several tools for such personalized examination were developed and discussed in this study. PMID:24694900

  6. Predicting Social Support for Grieving Persons: A Theory of Planned Behavior Perspective

    Science.gov (United States)

    Bath, Debra M.

    2009-01-01

    Research has consistently reported that social support from family, friends, and colleagues is an important factor in the bereaved person's ability to cope after the loss of a loved one. This study used a Theory of Planned Behavior framework to identify those factors that predict a person's intention to interact with, and support, a grieving…

  7. Information Behaviors and Information Literacy Skills of LIS Students: An International Perspective

    Science.gov (United States)

    Saunders, Laura; Kurbanoglu, Serap; Boustany, Joumana; Dogan, Guleda; Becker, Peter; Blumer, Eliane; Chowdhury, Sudatta; Dobreva, Milena; Gendina, Natalia; Grgic, Ivana Hebrang; Haddow, Gaby; Koltay, Tibor; Kortelainen, Terttu; Krakowska, Monika; Majid, Shaheen; Mezhova, Marina; Repanovici, Angela; Rudžioniene, Jurgita; Schneider, Rene; Terra, Ana Lucia; Todorova, Tania Y.

    2015-01-01

    Librarians are expected to be expert searchers, and developing information literacy skills to navigate the vast world of information is a focus of most library and information science (LIS) programs. It is important to understand the information literacy and behaviors of LIS students to see if they are employing the skills they will need to assist…

  8. Ninth Graders' Energy Balance Knowledge and Physical Activity Behavior: An Expectancy-Value Perspective

    Science.gov (United States)

    Chen, Senlin; Chen, Ang

    2012-01-01

    Expectancy beliefs and task values are two essential motivators in physical education. This study was designed to identify the relation between the expectancy-value constructs (Eccles & Wigfield, 1995) and high school students' physical activity behavior as associated with their energy balance knowledge. High school students (N = 195) in two…

  9. An Analysis of Colombian Power Market Price Behavior from an Industrial Organization Perspective

    Directory of Open Access Journals (Sweden)

    Ona Duarte Venslauskas

    2015-12-01

    Full Text Available We analyze the behavior of spot prices in the Colombian wholesale power market, using a series of models derived from industrial organization theory.  We first create a Cournot-based model that simulates the strategic behavior of the market-leader power generators, which we use to estimate two industrial organization variables, the Index of Residual Demand and the Herfindahl-Hirschman Index (HHI.  We use these variables to create VAR models that estimate spot prices and power market impulse-response relationships.  The results from these models show that hydroelectric generators can use their water storage capability strategically to affect off-peak prices primarily, while the thermal generators can manage their capacity strategically to affect on-peak prices.  In addition, shocks to the Index of Residual Capacity and to the HHI cause spot price fluctuations, which can be interpreted as the generators´ strategic response to these shocks.

  10. A meta-analysis of the Dark Triad and work behavior: a social exchange perspective.

    Science.gov (United States)

    O'Boyle, Ernest H; Forsyth, Donelson R; Banks, George C; McDaniel, Michael A

    2012-05-01

    We reviewed studies of the Dark Triad (DT) personality traits--Machiavellianism, narcissism, and psychopathy-and meta-analytically examined their implications for job performance and counterproductive work behavior (CWB). Relations among the DT traits and behaviors were extracted from original reports published between 1951 and 2011 of 245 independent samples (N = 43,907). We found that reductions in the quality of job performance were consistently associated with increases in Machiavellianism and psychopathy and that CWB was associated with increases in all 3 components of the DT, but that these associations were moderated by such contextual factors as authority and culture. Multivariate analyses demonstrated that the DT explains moderate amounts of the variance in counterproductivity, but not job performance. The results showed that the 3 traits are positively related to one another but are sufficiently distinctive to warrant theoretical and empirical partitioning. PMID:22023075

  11. Discipline and Flexibility: A Behavioral Perspective on Product Design in Microfinance

    OpenAIRE

    Labie, Marc; Laureti, Carolina; Szafarz, Ariane

    2016-01-01

    The success of both microcredit and micro-savings products rests upon simplicity and standardization in order to stimulate client discipline. Meanwhile, these products lack flexibility. This paper attempts to make sense of behavioral product design in microfinance. We focus on the potential trade-offs between discipline and flexibility. While discipline devices encourage clients make payments duly on time, flexibility improves clients’ day-to-day money management and helps them cope with shoc...

  12. Family Adversity, Positive Peer Relationships, and Children's Externalizing Behavior: A Longitudinal Perspective on Risk and Resilience

    OpenAIRE

    Criss, Michael M.; Pettit, Gregory S.; BATES, JOHN E.; Dodge, Kenneth A.; Lapp, Amie L.

    2002-01-01

    Peer acceptance and friendships were examined as moderators in the link between family adversity and child externalizing behavioral problems. Data on family adversity (i.e., ecological disadvantage, violent marital conflict, and harsh discipline) and child temperament and social information processing were collected during home visits from 585 families with 5-year-old children. Children's peer acceptance, friendship, and friends' aggressiveness were assessed with sociometric methods in kinder...

  13. The impact of culture and gender on leadership behavior: Higher education and management perspective

    OpenAIRE

    Muhammad Imran Qureshi; Khalid Zaman; Mansoor Nazir Bhatti

    2011-01-01

    The study of culture, gender and leadership behavior has received much interest from researchers during the last three decades. This paper attempts to propose a conceptual framework consisting three human resource management (HRM) practices (culture, gender and leadership styles) and to explain the relationship among these variables. Culture plays an important role to adopt different leadership styles because it influences the way in which individuals, groups and teams interact with each othe...

  14. Perceived Risk, the Internet Shopping Experience and Online Purchasing Behavior: A New Zealand Perspective

    OpenAIRE

    Bill Doolin; Stuart Dillon; Fiona Thompson; James L. Corner

    2005-01-01

    This paper develops a research model of the importance of consumers’ perceived risk and the Internet shopping experience in the online purchasing behavior of Internet users. The model was tested using a survey of some 700 New Zealand Internet users. Both the perceived risk and perceived benefits of Internet shopping were found to be significantly associated with the amount and frequency of online purchases made. Loss of social interaction in Internet shopping was associated with reduced onl...

  15. Parents’ empathic perspective taking and altruistic behavior predicts infants’ arousal to others’ emotions

    OpenAIRE

    Upshaw, Michaela B.; Kaiser, Cheryl R.; Sommerville, Jessica A.

    2015-01-01

    Empathy emerges in children’s overt behavior around the middle of the second year of life. Younger infants, however, exhibit arousal in response to others’ emotional displays, which is considered to be a precursor to fully developed empathy. The goal of the present study was to investigate individual variability in infants’ arousal toward others’ emotional displays, as indexed by 12- and 15-month-old infants’ (n = 49) pupillary changes in response to another infant’s emotions, and to determin...

  16. Understanding Internet Banking Adoption and Use Behavior: A Hong Kong Perspective

    OpenAIRE

    Siu-cheung Chan; Ming-te Lu

    2004-01-01

    This study investigates adoption/use behavior within the context of Hong Kong Internet Banking services. A research framework based on the extended Technology Acceptance Model (TAM2) and Social Cognitive Theory is developed to identify factors that would influence the adoption and continue use of Internet Banking. Structural Equation Modeling (SEM) is employed to examine the entire pattern of inter-correlations among the eight proposed constructs, and to test related propositions empirically....

  17. Intrasexual peer aggression and dating behavior during adolescence: an evolutionary perspective.

    Science.gov (United States)

    Gallup, Andrew C; O'Brien, Daniel T; Wilson, David Sloan

    2011-01-01

    It has been suggested that the use of intrasexual aggression is a form of competition associated with reproductive opportunities. Here the authors investigated the relationship between retrospective dating and flirting behavior and peer aggression and victimization during middle and high school. Results indicate that the use of peer aggression was associated with adaptive dating outcomes in both sexes, whereas experiencing peer victimization was correlated with maladaptive dating behaviors among females only. Females who perpetrated high levels of indirect (i.e. nonphysical) aggression reported that they began dating at earlier ages in comparison to their peers, whereas aggressive males reported having more total dating partners. Experiencing female-female peer victimization was correlated with a later onset of dating behavior, more total dating partners, and less male flirtation while growing up. This report strengthens the connection between adolescent peer aggression and reproductive competition, suggesting a potential functionality to adolescent peer aggression in enhancing one's own mating opportunities at the expense of rivals. PMID:21433032

  18. Cardiovascular Disease and Diabetes

    Science.gov (United States)

    ... Blood Pressure Tools & Resources Stroke More Cardiovascular Disease & Diabetes Updated:Mar 23,2016 The following statistics speak ... disease. This content was last reviewed August 2015. Diabetes • Home • About Diabetes • Why Diabetes Matters Introduction Cardiovascular ...

  19. Hybrid Societies: Challenges and Perspectives in the Design of Collective Behavior in Self-organizing Systems

    Directory of Open Access Journals (Sweden)

    Heiko eHamann

    2016-04-01

    Full Text Available Hybrid societies are self-organizing, collective systems composed of different components, for example, natural and artificial parts (bio-hybrid or human beings interacting with and through technical systems (socio-technical. Many different disciplines investigate methods and systems closely related to the design of hybrid societies. A~stronger collaboration between these disciplines could allow for re-use of methods and create significant synergies. We identify three main areas of challenges in the design of self-organizing hybrid societies. First, we identify the formalization challenge. There is an urgent need for a generic model that allows a description and comparison of collective hybrid societies. Second, we identify the system design challenge. Starting from the formal specification of the system, we need to develop an integrated design process. Third, we identify the challenge of interdisciplinarity. Current research on self-organizing hybrid societies stretches over many different fields and hence requires the re-use and synthesis of methods at intersections between disciplines. We then conclude by presenting our perspective for future approaches with high potential in this area.

  20. Infection and Cardiovascular Disease

    Science.gov (United States)

    2016-02-17

    Cardiovascular Diseases; Coronary Disease; Cerebrovascular Accident; Heart Diseases; Myocardial Infarction; Infection; Chlamydia Infections; Cytomegalovirus Infections; Helicobacter Infections; Atherosclerosis

  1. Cardiovascular safety of antipsychotics

    DEFF Research Database (Denmark)

    Polcwiartek, Christoffer; Sørensen, Kristian Dahl Kragholm; Schjerning, Ole; Graff, Claus; Nielsen, Jimmi

    2016-01-01

    cardiovascular risk factors. Areas covered: This clinical overview summarizes the cardiovascular safety of antipsychotics by focusing on the wide range of associated adverse effects. In addition, we also discuss current guidelines regarding routine electrocardiogram (ECG) monitoring. Expert opinion: As SCD in......, as this may increase risk of Torsades de Pointes and eventually SCD. However, other serious cardiovascular complications of antipsychotics also include Brugada syndrome phenotype, myocardial infarction, and myocarditis. Increased awareness of the cardiovascular safety of antipsychotics can allow...

  2. Electric Energy Management in the Smart Home: Perspectives on Enabling Technologies and Consumer Behavior: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Zipperer, A.; Aloise-Young, P. A.; Suryanarayanan, S.; Roche, R.; Earle, L.; Christensen, D.; Bauleo, P.; Zimmerle. D.

    2013-08-01

    Smart homes hold the potential for increasing energy efficiency, decreasing costs of energy use, decreasing the carbon footprint by including renewable resources, and transforming the role of the occupant. At the crux of the smart home is an efficient electric energy management system that is enabled by emerging technologies in the electric grid and consumer electronics. This article presents a discussion of the state-of-the-art in electricity management in smart homes, the various enabling technologies that will accelerate this concept, and topics around consumer behavior with respect to energy usage.

  3. Electric Energy Management in the Smart Home: Perspectives on Enabling Technologies and Consumer Behavior

    Energy Technology Data Exchange (ETDEWEB)

    Zipperer, A. [Colorado State Univ., Fort Collins, CO (United States); Aloise-Young, P. A. [Colorado State Univ., Fort Collins, CO (United States); Suryanarayanan, S. [Colorado State Univ., Fort Collins, CO (United States); Zimmerle, D. [Colorado State Univ., Fort Collins, CO (United States); Roche, R. [Univ. of Technology, Belfort-Montebeliard (France); Earle, L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Christensen, D. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Bauleo, P. [Fort Collins Utilities, CO (United States)

    2013-08-01

    Smart homes hold the potential for increasing energy efficiency, decreasing costs of energy use, decreasing the carbon footprint by including renewable resources, and trans-forming the role of the occupant. At the crux of the smart home is an efficient electric energy management system that is enabled by emerging technologies in the electricity grid and consumer electronics. This article presents a discussion of the state-of-the-art in electricity management in smart homes, the various enabling technologies that will accelerate this concept, and topics around consumer behavior with respect to energy usage.

  4. Effects of the lipid regulator drug gemfibrozil: A toxicological and behavioral perspective.

    Science.gov (United States)

    Henriques, Jorge F; Almeida, Ana Rita; Andrade, Thayres; Koba, Olga; Golovko, Oksana; Soares, Amadeu M V M; Oliveira, Miguel; Domingues, Inês

    2016-01-01

    Pharmaceuticals are emerging contaminants as their worldwide consumption increases. Fibrates such as gemfibrozil (GEM) are used in human medicine to reduce blood concentrations of cholesterol and triacylglycerol and also are some of the most frequently reported pharmaceuticals in waste waters and surface waters. Despite some studies have already demonstrated the negative impact in physiological and/or reproductive endpoints in adult fish, data on survival and behavioral effects in fish larvae are lacking. This study aimed to assess the effects of GEM on zebrafish eleutheroembryo development and locomotor behavior. A fish embryo toxicity (FET) test was undertaken to evaluate GEM acute toxicity by exposing embryos to 0, 6.58, 9.87, 14.81, 22.22, 33.33 and 50mg/L. Developmental endpoints such as hatching success, edemas and malformations were recorded. A second test was undertaken by exposing embryos to 0, 1.5, 3 and 6mg/L in order to evaluate the effects of GEM on 120 and 144h post fertilization (hpf) larvae locomotor activity by video tracking, using a Zebrabox(®) (Viewpoint, France) device. From the data recorded, several parameters such as total swimming distance (TSD) and total swimming time (TST) in each 120s integration time were calculated. Data showed that this compound has a moderate toxic effect on fish embryo development, affecting both survival and hatching success with a calculated 96h LC50 of 11.01mg/L and no effects at the developmental level at 6mg/L. GEM seems to impair locomotor activity, even at concentrations where developmental abnormalities were unperceived, at concentrations as low as 1.5mg/L. Both TSD and TST were sensitive to GEM exposure. These effects do not seem to be independent of the developmental stage as 120hpf larvae seem to present a development bias with repercussions in locomotor behavior. This study highlights the need to include behavioral endpoints in ecotoxicological assays as this seems to be a more sensitive endpoint often

  5. Typical Behavior of the Linear Programming Method for Combinatorial Optimization Problems: A Statistical-Mechanical Perspective

    Science.gov (United States)

    Takabe, Satoshi; Hukushima, Koji

    2014-04-01

    The typical behavior of the linear programming (LP) problem is studied as a relaxation of the minimum vertex cover problem, which is a type of integer programming (IP) problem. To deal with LP and IP using statistical mechanics, a lattice-gas model on the Erdös-Rényi random graphs is analyzed by a replica method. It is found that the LP optimal solution is typically equal to that given by IP below the critical average degree c*=e in the thermodynamic limit. The critical threshold for LP = IP extends the previous result c = 1, and coincides with the replica symmetry-breaking threshold of the IP.

  6. Effects of Granular Control on Customers’ Perspective and Behavior with Automated Demand Response Systems

    Energy Technology Data Exchange (ETDEWEB)

    Schetrit, Oren; Kim, Joyce; Yin, Rongxin; Kiliccote, Sila

    2014-08-01

    Automated demand response (Auto-DR) is expected to close the loop between buildings and the grid by providing machine-to-machine communications to curtail loads without the need for human intervention. Hence, it can offer more reliable and repeatable demand response results to the grid than the manual approach and make demand response participation a hassle-free experience for customers. However, many building operators misunderstand Auto-DR and are afraid of losing control over their building operation. To ease the transition from manual to Auto-DR, we designed and implemented granular control of Auto-DR systems so that building operators could modify or opt out of individual load-shed strategies whenever they wanted. This paper reports the research findings from this effort demonstrated through a field study in large commercial buildings located in New York City. We focused on (1) understanding how providing granular control affects building operators’ perspective on Auto-DR, and (2) evaluating the usefulness of granular control by examining their interaction with the Auto-DR user interface during test events. Through trend log analysis, interviews, and surveys, we found that: (1) the opt-out capability during Auto-DR events can remove the feeling of being forced into load curtailments and increase their willingness to adopt Auto-DR; (2) being able to modify individual load-shed strategies allows flexible Auto-DR participation that meets the building’s changing operational requirements; (3) a clear display of automation strategies helps building operators easily identify how Auto-DR is functioning and can build trust in Auto-DR systems.

  7. Social determinants, suboptimal health behavior, and morbidity in urban slum population: an Indian perspective.

    Science.gov (United States)

    Pawar, Ajay B; Mohan, Palipudi Venkata Trinada Krishna; Bansal, Rajkumar K

    2008-07-01

    Improving the health of urban residents, particularly those living in slum areas, requires an integrated approach. Appropriate interventions must be based on a well-grounded understanding of health determinants. Social factors are as important as physical factors in determining health status and suggest alternative interventions. Employment, stress, social exclusion, social support, substance use, nutrition, transport, and conditions during childhood are among the most important social determinants of health status identified by the International Center for Health and Society. This paper uses social determinants of health approach to understand morbidity outcomes for people residing in the slums of Surat City, India. To quantify suboptimal health behavior and identify the determinants of health status for this population survey data on household characteristics, health-seeking behavior, socioeconomic status, food and personal habits, social life, and physical activity has been used. After controlling for socioeconomic and demographic factors, logistic regression analysis reveals that social exclusion, stress, and lack of social support are significantly associated with morbidity. Thus, understanding of social determinants of health by policy makers is important as the health sector has a crucial role in addressing disparities in social determinants. PMID:18404392

  8. Altruism, egoism, or neither: A cognitive-efficiency-based evolutionary biological perspective on helping behavior.

    Science.gov (United States)

    Schulz, Armin W

    2016-04-01

    I argue for differences in the cognitive efficiency of different psychologies underlying helping behavior, and present an account of the adaptive pressures that result from these differences. Specifically, I argue that organisms often face pressure to move away from only being egoistically motivated to help: non-egoistic organisms are often able to determine how to help other organisms more quickly and with less recourse to costly cognitive resources like concentration and attention. Furthermore, I also argue that, while these pressures away from pure egoism can lead to the evolution of altruists, they can also lead to the evolution of reciprocation-focused behaviorist helpers or even of reflex-driven helpers (who are neither altruists nor egoists). In this way, I seek to broaden the set of considerations typically taken into account when assessing the evolution of the psychology of helping behavior-which tend to be restricted to matters of reliability-and also try to make clearer the role of evolutionary biological considerations in the discussion of this apparently straightforwardly psychological phenomenon. PMID:26778352

  9. [Cardiovascular safety of antidiabetics].

    Science.gov (United States)

    Aline Roth, Pressl-Wenger; Jornayvaz, François R

    2016-06-01

    Type 2 diabetes is characterized by a high risk of micro- and macro-vascular complications. Cardiovascular diseases are the leading cause of death of diabetic patients. In this context, the search for molecules decreasing cardiovascular mortality makes sense. Until the EMPA-REG OUTCOME study published late 2015, showing a reduction of cardiovascular mortality of patients treated with empagliflozin, an SGLT2 inhibitor, there was no molecule known to decrease cardiovascular mortality. The purpose of this article is to review the various existing antidiabetic molecules and their impact (positive/neutral/negative) on cardiovascular mortality. PMID:27487675

  10. Dealing with defaulting suppliers using behavioral based governance methods: An Agency Theory perspective

    DEFF Research Database (Denmark)

    Prosman, Ernst Johannes; Scholten, Kirstin; Power, Damien

    2016-01-01

    Purpose: The aim of this paper is to explore factors influencing the effectiveness of buyer initiated Behavioral Based Governance Methods (BBGMs). The ability of BBGMs to improve supplier performance is assessed considering power imbalances and the resource intensiveness of the BBGM. Agency Theory...... considering power differences and the resource intensiveness of the BBGM. Our data show that even high resource intensive BBGMs can be implemented effectively if there are benefits for a powerful supplier. Cultural influences and uncertainty of the business environment also play a role. Originality....../value: This study develops a series of propositions indicating that Agency Theory can provide valuable guidance on how to better understand the effectiveness of BBGMs. Underlying mechanisms are identified that explain how power imbalances do not necessarily make improvement initiatives unsuccessful....

  11. The impact of culture and gender on leadership behavior: Higher education and management perspective

    Directory of Open Access Journals (Sweden)

    Muhammad Imran Qureshi

    2011-10-01

    Full Text Available The study of culture, gender and leadership behavior has received much interest from researchers during the last three decades. This paper attempts to propose a conceptual framework consisting three human resource management (HRM practices (culture, gender and leadership styles and to explain the relationship among these variables. Culture plays an important role to adopt different leadership styles because it influences the way in which individuals, groups and teams interact with each other and cooperate to achieve organizational goals. The seven cultural elements are measured in the current study i.e., i member identity ii rewards criteria iii team emphasis iv means-end orientation v control vi unit integration and vii risk/ conflict tolerance. Results show that the culture has a significant influence on male leaders to adopt different leadership styles, but female leaders likely participative in their leadership positions and try to adopt democratic leadership in different cultures.

  12. SOCIAL FACTORS INFLUENCE FROM THE PERSPECTIVE OF DENTAL HEALTHCARE SERVICES CONSUMERS’ BEHAVIOR

    Directory of Open Access Journals (Sweden)

    Iuliana Petronela Gârdan

    2016-01-01

    Full Text Available In case of dental care consumption, a very special influence will have the social factors. This influence, from the level of consumers’ behavior can be analyzed on two distinct levels – that of normatives impose by the social organization particular for the community that the individual live and that of the influences of the social groups that individual are interacting with. Dental healthcare services consumption is conditioned at the level of consumption motivations by complex needs which are not confined only to the physiological needs of removing pain caused by a certain dental condition, but are going towards the need of self-image improvement, increasing the appreciation offered by the others group members, the congruence with other consumers decisions within the group (family members, friends, colleagues etc. It is important to note in this context the fact that the influence exerted by consumers exogenous factors (external influences in which we can integrate those from the social groups also will be combined with the one exerted by endogenous factors (personality, learning process, perceptions, attitudes, motivations etc, representing a continuum that shape consumers and allows in the same time the society shaping by them. The present article proposes a research conducted on dental healthcare services consumers. Results revealed the importance that a series of variables like the importance given to image in the workplace, family, friends and colleagues perception towards dental aesthetic, social class has in the context of consumer behavior. It is also noted that the influence of variables is mediated by the importance given to self-image, dental healthcare services consumption being determined by complex needs, consumption motivations being physiological – specific to some medical conditions and psychological – aesthetic or induced by the pressure corresponding to the need to comply with social norms.

  13. Validation of a rat behavioral avoidance model from a drug delivery perspective.

    Science.gov (United States)

    Bhat, Meenakshi G; Jordt, Raymond M; Khan, M Amin; Foley, Christine E; Gilbertson, Timothy A

    2005-10-13

    Conventional taste-masking strategies are used to overcome the bitter taste perception of pharmaceuticals by coating the drug particles and/or adding flavoring agents. However, for certain product categories such as rapid dissolve sublingual tablets, taste-masking is challenging. Programs exploring such formulation strategies in the LO-CS phase or post CS phase possess very little toxicological information available in order to conduct human taste panel studies. The potential of a bitter taste perception can present a significant business risk. The objective of the study was to validate a rat behavioral avoidance model that identifies bitter-tasting compounds. Most classic bitter substances elicit a response in the micromolar concentration range while most drugs elicit a response in the millimolar range, hence a validation exercise was conducted to examine if the existing biological model was sensitive enough to identify known bitter tasting drugs as such. Five compounds: ergotamine tartrate, fluoxetine, sucrose, sumatriptan and povidone were chosen to represent a spectrum of compounds. The bitter tasting compounds were identified as such in the model. Based on these results, the assay may serve as a useful surrogate test to identify compounds that may have bitter taste issues. PMID:16125347

  14. Factors predicting BCG immunization status in northern Nigeria: a behavioral-ecological perspective.

    Science.gov (United States)

    Babalola, Stella; Lawan, Umar

    2009-03-01

    This study examines the predictors of Bacille Calmette-Guérin (BCG) immunization status among infants in northern Nigeria using a behavioral-ecological model. The findings show only 37.3 percent of the children had received BCG vaccine, and reveal that BCG immunization status in northern Nigeria is influenced by multiple layers of factors, including child's characteristics, parental or household factors, community characteristics, vaccine supply and the policy environment. At the child's level, place of birth and ownership of an immunization card are the two most significant predictors. The parental and household predictors of BCG immunization status include maternal use of antenatal care, maternal knowledge about immunization, maternal exposure to child health information, social influence and paternal approval of immunization. Both the regularity of vaccine supply to the health facility and the state of residence are associated independently with BCG immunization status. These findings stress the need for interventions at multiple levels in order to increase BCG immunization status. PMID:19240190

  15. Muscle architecture of the common chimpanzee (Pan troglodytes): perspectives for investigating chimpanzee behavior.

    Science.gov (United States)

    Carlson, Kristian J

    2006-07-01

    Thorpe et al. (Am J Phys Anthropol 110:179-199, 1999) quantified chimpanzee (Pan troglodytes) muscle architecture and joint moment arms to determine whether they functionally compensated for structural differences between chimpanzees and humans. They observed enough distinction to conclude that musculoskeletal properties were not compensatory and suggested that chimpanzees and humans do not exhibit dynamically similar movements. These investigators based their assessment on unilateral limb musculatures from three male chimpanzees, of which they called one non-adult representative. Factors such as age, sex, and behavioral lateralization may be responsible for variation in chimpanzee muscle architecture, but this is presently unknown. While the full extent of variation in chimpanzee muscle architecture due to such factors cannot be evaluated with data presently available, the present study expands the chimpanzee dataset and provides a preliminary glimpse of the potential relevance of these factors. Thirty-seven forelimb and 36 hind limb muscles were assessed in two chimpanzee cadavers: one unilaterally (right limbs), and one bilaterally. Mass, fiber length, and physiological cross-sectional area (PCSA) are reported for individual muscles and muscle groups. The musculature of an adult female is more similar in architectural patterns to a young male chimpanzee than to humans, particularly when comparing muscle groups. Age- and sex-related intraspecific differences do not obscure chimpanzee-human interspecific differences. Side asymmetry in one chimpanzee, despite consistent forelimb directional asymmetry, also does not exceed the magnitude of chimpanzee-human differences. Left forelimb muscles, on average, usually had higher masses and longer fiber lengths than right, while right forelimb muscles, on average, usually had greater PCSAs than left. Most muscle groups from the left forelimb exhibited greater masses than right groups, but group asymmetry was significant

  16. New perspectives on dairy and cardiovascular health.

    Science.gov (United States)

    Lovegrove, Julie A; Hobbs, Ditte A

    2016-08-01

    CVD are the leading cause of mortality and morbidity worldwide. One of the key dietary recommendations for CVD prevention is reduction of saturated fat intake. Yet, despite milk and dairy foods contributing on average 27 % of saturated fat intake in the UK diet, evidence from prospective cohort studies does not support a detrimental effect of milk and dairy foods on risk of CVD. The present paper provides a brief overview of the role of milk and dairy products in the diets of UK adults, and will summarise the evidence in relation to the effects of milk and dairy consumption on CVD risk factors and mortality. The majority of prospective studies and meta-analyses examining the relationship between milk and dairy product consumption and risk of CVD show that milk and dairy products, excluding butter, are not associated with detrimental effects on CVD mortality or risk biomarkers that include serum LDL-cholesterol. In addition, there is increasing evidence that milk and dairy products are associated with lower blood pressure and arterial stiffness. These apparent benefits of milk and dairy foods have been attributed to their unique nutritional composition, and suggest that the elimination of milk and dairy may not be the optimum strategy for CVD risk reduction. PMID:26907978

  17. Hyperhomocysteinemia and cardiovascular disease: The nutritional perspectives

    OpenAIRE

    Pandey, Rajesh; Gupta, Seema; Lal, Harbans; Mehta, H. C.; Aggarwal, S K

    2000-01-01

    Several members of the vitamin B-complex family are known to participate in the normal metabolism of homocysteine (Hcy). Leaving aside the genetic determinants of hyperhomocysteinemia (HHC), the deficiencies of these vitamins can also result in HHC. The situation of sustained and long standing HHC is likely to be prevalent in population groups with low/average socio-economic status, geriatric population and alcohol abusers. If not corrected by supplementation, these population groups certainl...

  18. Autophagy in cardiovascular biology

    OpenAIRE

    Lavandero, Sergio; Chiong, Mario; Rothermel, Beverly A.; Hill, Joseph A.

    2015-01-01

    Cardiovascular disease is the leading cause of death worldwide. As such, there is great interest in identifying novel mechanisms that govern the cardiovascular response to disease-related stress. First described in failing hearts, autophagy within the cardiovascular system has been widely characterized in cardiomyocytes, cardiac fibroblasts, endothelial cells, vascular smooth muscle cells, and macrophages. In all cases, a window of optimal autophagic activity appears to be critical to the mai...

  19. Cardiovascular molecular MR imaging

    OpenAIRE

    Lamb, H J; van der Meer, R. W.; Roos, A. (Anna); Bax, J J

    2007-01-01

    Introduction Cardiovascular molecular imaging is a rapidly evolving field of research, aiming to image and quantify molecular and cellular targets in vivo. MR imaging has some inherent properties that make it very suitable for cardiovascular molecular imaging. Until now, only a limited number of studies have been published on cardiovascular molecular imaging using MR imaging. Review In the current review, MR techniques that have already shown potential are discussed. Metabolic MR imaging can ...

  20. Primary prevention of diabetes mellitus type 2 and cardiovascular diseases using a cognitive behavior program aimed at lifestyle changes in people at risk: Design of a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Chinapaw Marijke J

    2008-06-01

    Full Text Available Abstract Background The number of people with cardiovascular disease (CVD and diabetes mellitus type 2 (T2DM is growing rapidly. To a large extend, this increase is due to lifestyle-dependent risk factors, such as overweight, reduced physical activity, and an unhealthy diet. Changing these risk factors has the potential to postpone or prevent the development of T2DM and CVD. It is hypothesized that a cognitive behavioral program (CBP, focused in particular on motivation and self-management in persons who are at high risk for CVD and/or T2DM, will improve their lifestyle behavior and, as a result, will reduce their risk of developing T2DM and CVD. Methods 12,000 inhabitants, 30-50 years of age living in several municipalities in the semi-rural region of West-Friesland will receive an invitation from their general practitioner (n = 13 to measure their own waist circumference with a tape measure. People with abdominal obesity (male waist ≥ 102 cm, female waist ≥ 88 cm will be invited to participate in the second step of the screening which includes blood pressure, a blood sample and anthropometric measurements. T2DM and CVD risk scores will then be calculated according to the ARIC and the SCORE formulae, respectively. People with a score that indicates a high risk of developing T2DM and/or CVD will then be randomly assigned to the intervention group (n = 300 or the control group (n = 300. Participants in the intervention group will follow a CBP aimed at modifying their dietary behavior, physical activity, and smoking behavior. The counseling methods that will be used are motivational interviewing (MI and problem solving treatment (PST, which focus in particular on intrinsic motivation for change and self-management of problems of the participants. The CBP will be provided by trained nurse practitioners in the participant's general practice, and will consists of a maximum of six individual sessions of 30 minutes, followed by 3-monthly booster

  1. Pervasive roles of microRNAs in cardiovascular biology

    OpenAIRE

    Small, Eric M.; Olson, Eric N.

    2011-01-01

    First recognized as regulators of development in worms and fruitflies, microRNAs are emerging as pivotal modulators of mammalian cardiovascular development and disease. Individual microRNAs modulate the expression of collections of messenger RNA targets that often have related functions, thereby governing complex biological processes. The wide-ranging functions of microRNAs in the cardiovascular system have provided new perspectives on disease mechanisms and have revealed intriguing therapeut...

  2. Lifestyle in Cardiovascular Disease

    NARCIS (Netherlands)

    J.O. Younge (John)

    2015-01-01

    markdownabstract__Abstract__ Globally, the burden of cardiovascular disease (CVD) is still increasing. However, in recent decades, better treatment modalities have led to less cardiovascular related deaths. After years of research, we now generally accept that lifestyle factors are the most importa

  3. Cardiovascular manifestations in hyperthyroidism

    OpenAIRE

    Vairamani Kandan; Sathyamurthy P; Rajkumar M; Lavanya Narayanan

    2016-01-01

    Background: It is well known that thyroid hormone directly affects the heart and peripheral vascular system. In hyperthyroidism, cardiovascular manifestations are frequent findings. Atrial arrhythmias, limitations in exercise tolerance, and congestive heart failure were reported to occur more common in older patients as a result of hyperthyroidism. Cardiovascular signs of hyperthyroidism include tachycardia, widened pulse pressure, marked increase in cardiac output with impaired cardiovascula...

  4. Triglycerides and cardiovascular disease

    DEFF Research Database (Denmark)

    Nordestgaard, Børge G; Varbo, Anette

    2014-01-01

    cholesterol might not cause cardiovascular disease as originally thought has now generated renewed interest in raised concentrations of triglycerides. This renewed interest has also been driven by epidemiological and genetic evidence supporting raised triglycerides, remnant cholesterol, or triglyceride......-rich lipoproteins as an additional cause of cardiovascular disease and all-cause mortality. Triglycerides can be measured in the non-fasting or fasting states, with concentrations of 2-10 mmol/L conferring increased risk of cardiovascular disease, and concentrations greater than 10 mmol/L conferring increased risk...... of acute pancreatitis and possibly cardiovascular disease. Although randomised trials showing cardiovascular benefit of triglyceride reduction are scarce, new triglyceride-lowering drugs are being developed, and large-scale trials have been initiated that will hopefully provide conclusive evidence...

  5. THE POLITICAL BEHAVIOR INTENTION IN INFORMATION SYSTEM DEVELOPMENT FROM MIS PROFESSIONALS' PERSPECTIVE: A STUDY BASED ON THE THEORY OF PLANNED BEHAVIOR

    OpenAIRE

    CHRISTINA LING-HSING CHANG

    2006-01-01

    The purpose of this study is to analyze the major variables influencing the political behavior of MIS professionals in information system development (ISD). The Theory of Planned Behavior (TPB) is used to create the research model. We found that (1) Attitude, subjective norm, perceived political behavior control and perceived political efficacy have different effects on MIS professionals' intention with regard to political behavior in four scenarios; (2) Machiavellism significantly affects MI...

  6. 代际划分视角下矿工不安全行为研究%Research on Miners'Unsafe Behaviors from the Perspective of Intergeneration

    Institute of Scientific and Technical Information of China (English)

    程恋军; 仲维清

    2016-01-01

    Based on the theory of planned behavior ( TPB) and the health action process approach ( HAPA) , this study constructs an integrated model of miners'unsafe behaviors to explore the new-generation miners'unsafe behavior from the per-spective of intergeneration.Findings from the survey of 468 miners's unsafe behaviors are as follows:first, there are significant differences between the new-generation miners'unsafe behaviors and those of other groups of miners;second, the unsafe behav-ior attitudes have a less significant effect on new-generation miners'behavioral intention, and the mediated effect of response plan is lower too;thirs, the risk perception of unsafe behaviors and subjective norms can directly affect the new-generation minors'unsafe behavior intention.%本文在计划行为理论(TPB)和健康行动过程取向理论(HAPA)的基础上构建矿工不安全行为整合理论模型, 从代际的视角探讨新生代矿工不安全行为产生的特点. 通过对468名矿工不安全行为的问卷调查发现, 与其他矿工群体相比, 新生代矿工在不安全行为产生路径上存在显著差异; 新生代矿工不安全行为态度对行为意向的影响较低, 应对计划的中介效应较低; 不安全行为的风险知觉和主观规范能直接影响新生代矿工不安全行为意向.

  7. Molecular cardiovascular imaging

    International Nuclear Information System (INIS)

    Although huge and long-lasting research efforts have been spent on the development of new diagnostic techniques investigating cardiovascular diseases, still fundamental challenges exist; the main challenge being the diagnosis of a suspected or known coronary artery disease or its consequences (myocardial infarction, heart failure etc.). Beside morphological techniques, functional imaging modalities are available in clinical diagnostic algorithms, whereas molecular cardiovascular imaging techniques are still under development. This review summarizes clinical-diagnostical challenges of modern cardiovascular medicine as well as the potential of new molecular imaging techniques to face these. (orig.)

  8. Cardiovascular disease: primary prevention, disease modulation and regenerative therapy.

    LENUS (Irish Health Repository)

    Sultan, Sherif

    2012-10-01

    Cardiovascular primary prevention and regeneration programs are the contemporary frontiers in functional metabolic vascular medicine. This novel science perspective harnesses our inherent ability to modulate the interface between specialized gene receptors and bioavailable nutrients in what is labeled as the nutrient-gene interaction. By mimicking a natural process through the conveyance of highly absorbable receptor specific nutrients, it is feasible to accelerate cell repair and optimize mitochondrial function, thereby achieving cardiovascular cure. We performed a comprehensive review of PubMed, EMBASE and Cochrane Review databases for articles relating to cardiovascular regenerative medicine, nutrigenomics and primary prevention, with the aim of harmonizing their roles within contemporary clinical practice. We searched in particular for large-scale randomized controlled trials on contemporary cardiovascular pharmacotherapies and their specific adverse effects on metabolic pathways which feature prominently in cardiovascular regenerative programs, such as nitric oxide and glucose metabolism. Scientific research on \\'cardiovascular-free\\' centenarians delineated that low sugar and low insulin are consistent findings. As we age, our insulin level increases. Those who can decelerate the rapidity of this process are prompting their cardiovascular rejuvenation. It is beginning to dawn on some clinicians that contemporary treatments are not only failing to impact on our most prevalent diseases, but they may be causing more damage than good. Primary prevention programs are crucial elements for a better outcome. Cardiovascular primary prevention and regeneration programs have enhanced clinical efficacy and quality of life and complement our conventional endovascular practice.

  9. Effect of different processings on mechanical property and corrosion behavior in simulated body fluid of Mg-Zn-Y-Nd alloy for cardiovascular stent application

    Science.gov (United States)

    Zhu, Shi-Jie; Liu, Qian; Qian, Ya-Feng; Sun, Bin; Wang, Li-Guo; Wu, Jing-Min; Guan, Shao-Kang

    2014-09-01

    The biomagnesium alloys have been considered to be one of the most potential biodegradable metal materials due to its good mechanical compatibility, biological compatibility, biological security and biodegradable characteristics. However, the two major problems of high degradation rates in physiological environment and low mechanical properties prevent the development of biomagnesium alloys. In the present work, the samples of Mg-Zn-Y-Nd alloy were prepared by cyclic extrusion compression (CEC) and equal channel angular pressing (ECAP). The microstructures, mechanical properties of alloy and its corrosion behavior in simulated body fluid (SBF) were evaluated. The results reveal that Mg-Zn-Y-Nd alloy consists of equiaxial fine grain structure with the homogeneous distribution of micrometer size and nano-sized second phase, which was caused by the dynamic recrystallization during the ECAP and CEC. The corrosion resistance of alloy was improved. The tensile and corrosion resistance were improved, especially the processed alloy exhibit uniform corrosion performances and decreased corrosion rate. This will provide theoretical ground for Mg-Zn-Y-Nd alloy as vascular stent application.

  10. Depression and cardiovascular disease.

    Science.gov (United States)

    Bradley, Steven M; Rumsfeld, John S

    2015-10-01

    There is a wealth of evidence linking depression to increased risk for cardiovascular disease (CVD) and worse outcomes among patients with known CVD. In addition, there are safe and effective treatments for depression. Despite this, depression remains under-recognized and undertreated in patients at risk for or living with CVD. In this review, we first summarize the evidence linking depression to increased risk of CVD and worse patient outcomes. We then review the mechanisms by which depression may contribute to cardiovascular risk and poor cardiovascular outcomes. We then summarize prior studies of depression treatment on cardiovascular outcomes. Finally, we offer guidance in the identification and management of depression among CVD populations. Given that 1 in 4 CVD patients has concurrent depression, application of these best-practices will assist providers in achieving optimal outcomes for their CVD patients. PMID:25850976

  11. Implicit Partitioned Cardiovascular Fluid-Structure Interaction of the Heart Cycle Using Non-newtonian Fluid Properties and Orthotropic Material Behavior.

    Science.gov (United States)

    Muehlhausen, M-P; Janoske, U; Oertel, H

    2015-03-01

    Although image-based methods like MRI are well-developed, numerical simulation can help to understand human heart function. This function results from a complex interplay of biochemistry, structural mechanics, and blood flow. The complexity of the entire system often causes one of the three parts to be neglected, which limits the truth to reality of the reduced model. This paper focuses on the interaction of myocardial stress distribution and ventricular blood flow during diastole and systole in comparison to a simulation of the same patient-specific geometry with a given wall movement (Spiegel, Strömungsmechanischer Beitrag zur Planung von Herzoperationen, 2009). The orthotropic constitutive law proposed by Holzapfel et al. (Philos. Trans. R. Soc. Lond. Ser. A, 367:3445-3475, 2009) was implemented in a finite element package to model the passive behavior of the myocardium. Then, this law was modified for contraction. Via the ALE method, the structural model was coupled to a flow model which incorporates blood rheology and the circulatory system (Oertel, Prandtl-Essentials of Fluid Mechanics, 3rd edn, Springer Science + Business Media, 2010; Oertel et al., Modelling the Human Cardiac Fluid Mechanics, 3rd edn, Universitätsverlag Karlsruhe, 2009). Comparison reveals a good quantitative and qualitative agreement with respect to fluid flow. The motion of the myocardium is consistent with physiological observations. The calculated stresses and the distribution are within the physiological range and appear to be reasonable. The coupled model presented contains many features essential to cardiac function. It is possible to calculate wall stresses as well as the characteristic ventricular fluid flow. Based on the simulations we derive two characteristics to assess the health state quantitatively including solid and fluid mechanical aspects. PMID:26577098

  12. Violence and Cardiovascular Health

    Science.gov (United States)

    Suglia, Shakira F.; Sapra, Katherine J.; Koenen, Karestan C.

    2014-01-01

    Context Violence, experienced in either childhood or adulthood, has been associated with physical health outcomes including cardiovascular disease. However, the consistency of the existing literature has not been evaluated. Evidence acquisition In 2013, the authors conducted a PubMed and Web of Science review of peer reviewed articles published prior to August 2013 on the relation between violence exposure, experienced in either childhood or adulthood, and cardiovascular outcomes. To meet inclusion criteria, articles had to present estimates for the relation between violence exposure and cardiovascular outcomes (hypertension, blood pressure, stroke, coronary disease, or myocardial infarction) adjusted for demographic factors. Articles focusing on violence from TV, video games, natural disasters, terrorism, or war were excluded. Evidence synthesis The initial search yielded 2,273 articles; after removing duplicates and applying inclusion and exclusion criteria, 30 articles were selected for review. A consistent positive relation was noted on the association between violence experienced during childhood and cardiovascular outcomes in adulthood (i.e., hypertension, coronary heart disease, and myocardial infarction). Associations across genders with varying types of violence exposure were also noted. By contrast, findings were mixed on the relation between adult violence exposure and cardiovascular outcome. Conclusions Despite varying definitions of violence exposure and cardiovascular endpoints, a consistent relation exists between childhood violence exposure, largely assessed retrospectively, and cardiovascular endpoints. Findings are mixed for the adult violence–cardiovascular health relation. The cross-sectional nature of most adult studies and the reliance of self-reported outcomes can potentially be attributed to the lack of findings among adult violence exposure studies. PMID:25599905

  13. Epigenetic Changes in Diabetes and Cardiovascular Risk.

    Science.gov (United States)

    Keating, Samuel T; Plutzky, Jorge; El-Osta, Assam

    2016-05-27

    Cardiovascular complications remain the leading causes of morbidity and premature mortality in patients with diabetes mellitus. Studies in humans and preclinical models demonstrate lasting gene expression changes in the vasculopathies initiated by previous exposure to high glucose concentrations and the associated overproduction of reactive oxygen species. The molecular signatures of chromatin architectures that sensitize the genome to these and other cardiometabolic risk factors of the diabetic milieu are increasingly implicated in the biological memory underlying cardiovascular complications and now widely considered as promising therapeutic targets. Atherosclerosis is a complex heterocellular disease where the contributing cell types possess distinct epigenomes shaping diverse gene expression. Although the extent that pathological chromatin changes can be manipulated in human cardiovascular disease remains to be established, the clinical applicability of epigenetic interventions will be greatly advanced by a deeper understanding of the cell type-specific roles played by writers, erasers, and readers of chromatin modifications in the diabetic vasculature. This review details a current perspective of epigenetic mechanisms of macrovascular disease in diabetes mellitus and highlights recent key descriptions of chromatinized changes associated with persistent gene expression in endothelial, smooth muscle, and circulating immune cells relevant to atherosclerosis. Furthermore, we discuss the challenges associated with pharmacological targeting of epigenetic networks to correct abnormal or deregulated gene expression as a strategy to alleviate the clinical burden of diabetic cardiovascular disease. PMID:27230637

  14. Gender Perspectives on Adolescent Eating Behaviors: A Study on the Eating Attitudes and Behaviors of Junior Secondary Students in Hong Kong

    Science.gov (United States)

    Lai Yeung, Wai-ling Theresa

    2010-01-01

    Objective: This research aimed to investigate the eating attitudes and behaviors of junior secondary students in Hong Kong, with a specific focus on possible gender differences. Design: A survey was conducted in 2005 to solicit data about participants' food knowledge, eating attitudes and behavior, perceptions of cooking skills and body weight,…

  15. Incremental Validity and Informant Effect from a Multi-Method Perspective: Assessing Relations between Parental Acceptance and Children’s Behavioral Problems

    Science.gov (United States)

    Izquierdo-Sotorrío, Eva; Holgado-Tello, Francisco P.; Carrasco, Miguel Á.

    2016-01-01

    This study examines the relationships between perceived parental acceptance and children’s behavioral problems (externalizing and internalizing) from a multi-informant perspective. Using mothers, fathers, and children as sources of information, we explore the informant effect and incremental validity. The sample was composed of 681 participants (227 children, 227 fathers, and 227 mothers). Children’s (40% boys) ages ranged from 9 to 17 years (M = 12.52, SD = 1.81). Parents and children completed both the Parental Acceptance Rejection/Control Questionnaire (PARQ/Control) and the check list of the Achenbach System of Empirically Based Assessment (ASEBA). Statistical analyses were based on the correlated uniqueness multitrait-multimethod matrix (model MTMM) by structural equations and different hierarchical regression analyses. Results showed a significant informant effect and a different incremental validity related to which combination of sources was considered. A multi-informant perspective rather than a single one increased the predictive value. Our results suggest that mother–father or child–father combinations seem to be the best way to optimize the multi-informant method in order to predict children’s behavioral problems based on perceived parental acceptance. PMID:27242582

  16. On the linear discrepancy model and risky shifts in group behavior: a nonlinear Fokker-Planck perspective

    Energy Technology Data Exchange (ETDEWEB)

    Frank, T D [Center for the Ecological Study of Perception and Action, Department of Psychology, University of Connecticut, 406 Babbidge Road, Storrs, CT 06269 (United States)

    2009-04-17

    Using a nonlinear Fokker-Planck perspective we re-formulate the linear discrepancy model proposed by Boster and colleagues that describes the emergence of risky shifts during group decision making. Analytical expressions for the stationary case are derived and risky shifts are obtained by Monte Carlo simulations. Striking similarities with the Kuramoto model for group synchronization are pointed out.

  17. On the linear discrepancy model and risky shifts in group behavior: a nonlinear Fokker-Planck perspective

    International Nuclear Information System (INIS)

    Using a nonlinear Fokker-Planck perspective we re-formulate the linear discrepancy model proposed by Boster and colleagues that describes the emergence of risky shifts during group decision making. Analytical expressions for the stationary case are derived and risky shifts are obtained by Monte Carlo simulations. Striking similarities with the Kuramoto model for group synchronization are pointed out

  18. Cardiovascular outcome trials for anti-diabetes medication: A holy grail of drug development?

    Science.gov (United States)

    John, Mathew; Gopalakrishnan Unnikrishnan, Ambika; Kalra, Sanjay; Nair, Tiny

    2016-01-01

    Since the time questions arose on cardiovascular safety of Rosiglitazone, FDA has suggested guidelines on conduct of studies on anti-diabetic drugs so as to prove that the cardiovascular risk is acceptable. Based on the cardiovascular risks of pre-approval clinical trials, guidelines have been made to conduct cardiovascular safety outcome trials (CVSOTs) prior to the drug approval or after the drug has been approved. Unlike the trials comparing the efficacy of antidiabetic agents, the CVSOTs examine the cardiovascular safety of a drug in comparison to standard of care. These trials are expensive aspects of drug development and are associated with various technical and operational challenges. More cost effective models of assessing cardiovascular safety like use of biomarkers, electronic medical records, pragmatic and factorial designs can be adopted. This article critically looks at the antidiabetic drug approval from a cardiovascular perspective by asking a few questions and arriving at answers. PMID:27543483

  19. Adult ADHD Medications and Their Cardiovascular Implications.

    Science.gov (United States)

    Sinha, A; Lewis, O; Kumar, R; Yeruva, S L H; Curry, B H

    2016-01-01

    Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder exhibited by difficulty maintaining attention, as well as hyperactivity and impulsive behavior. Central nervous system (CNS) stimulants are the first line of treatment for ADHD. With the increase in number of adults on CNS stimulants, the question that arises is how well do we understand the long-term cardiovascular effects of these drugs. There has been increasing concern that adults with ADHD are at greater risk for developing adverse cardiovascular events such as sudden death, myocardial infarction, and stroke as compared to pediatric population. Cardiovascular response attributed to ADHD medication has mainly been observed in heart rate and blood pressure elevations, while less is known about the etiology of rare cardiovascular events like acute myocardial infarction (AMI), arrhythmia, and cardiomyopathy and its long-term sequelae. We present a unique case of AMI in an adult taking Adderall (mixed amphetamine salts) and briefly discuss the literature relevant to the cardiovascular safety of CNS stimulants for adult ADHD. PMID:27579185

  20. Matriarchal model for cardiovascular prevention.

    Science.gov (United States)

    Wild, R A; Taylor, E L; Knehans, A; Cleaver, V

    1994-02-01

    Family patterns of cardiovascular risk behavior are well documented. Significant correlation exists between spouse-spouse, parent-child, and sibling-sibling for cholesterol, high- and low-density lipoprotein, diet, physical activity, and smoking. Family/environmental influences are important in how/if risk and/or preventive behavior is learned. The family matriarch commonly functions as gatekeeper, controlling eating behavior, access to health care, and other patterns. She often acts as menu planner, shopper, and preparer of meals for all family members. She provides information and verbal reinforcement about food and is a powerful model concerning dietary practices. In fact, the mother, as head of household in most single-parent families, may be the only adult model for many children. Because relevance and credibility are the most important characteristics of a behavioral model, parents (especially mothers) are strong models for observational learning by children. Risk factor information and risk reduction activities adopted by the matriarch can be generalized to the entire family if she learns the skills to act as a change agent. Initiation of this process of education and training the matriarch lies with primary care providers for women (Ob-Gyns see most women). By teaching risk reduction to the matriarch as a component of primary care, physician interaction can have a rippling effect. PMID:8164913

  1. Environmental Management in Small and Medium-Sized Companies: An Analysis from the Perspective of the Theory of Planned Behavior

    OpenAIRE

    Sánchez-Medina, Agustín J.; Leonardo Romero-Quintero; Silvia Sosa-Cabrera

    2014-01-01

    In the business context, concern for the environment began to develop when pressure from the public administration and environmental awareness groups raised the specific requirements for companies. The Theory of Planned Behavior considers that people's conduct is determined by the intention of carrying out a certain behavior. Thus, the individual's intent is determined by three factors related to the desired outcome of the behavior: the Personal Attitude toward the Results, the Perceived Soci...

  2. 比较法视野下的自助行为制度研究%Perspective of Comparative Law Behavior

    Institute of Scientific and Technical Information of China (English)

    肖玉超

    2012-01-01

    Self acts as the civil rights of private relief one way, as confirmed by modem civ- il law countries, its function is to compensate for the inadequacy of public relief. Based on the two countries, namely China and Japan, a typical case of the analysis, the perspective of the self- help behavior of the constituent elements, then this article from the perspective of comparative law self-help behavior and violations, the last article in the draft civil law and civil law self-help behavior the state's code, such as "German Civil Code" ," Thai civil Code" in the conduct of a self-analysis of comparative law, and involve the civil law and common law countries, acts of self-comparison.%自助行为作为民事权利私力救济的方式之一。为近现代各回民法所确认,其功能在于弥补公力救济之不足。文章通过时两个固家即中回和日本典型素例的分析。透视了自助行为的构成要件.然后从比较法的角度分析自助行为与使权行为。最后将民法革素中的自助行为与大陆法系圈謇的法兵如《德国民法典》、《泰国民法典》中的自助行为进行了比较法分析,并涉及了大陆法系和英芙法系圈謇自助行为的比较。

  3. Marathon run: cardiovascular adaptation and cardiovascular risk.

    Science.gov (United States)

    Predel, Hans-Georg

    2014-11-21

    The first marathon run as an athletic event took place in the context of the Olympic Games in 1896 in Athens, Greece. Today, participation in a 'marathon run' has become a global phenomenon attracting young professional athletes as well as millions of mainly middle-aged amateur athletes worldwide each year. One of the main motives for these amateur marathon runners is the expectation that endurance exercise (EE) delivers profound beneficial health effects. However, with respect to the cardiovascular system, a controversial debate has emerged whether the marathon run itself is healthy or potentially harmful to the cardiovascular system, especially in middle-aged non-elite male amateur runners. In this cohort, exercise-induced increases in cardiac biomarkers-troponin and brain natriuretic peptide-and acute functional cardiac alterations have been observed and interpreted as potential cardiac damage. Furthermore, in the cohort of 40- to 65-year-old males engaged in intensive EE, a significant risk for the development of atrial fibrillation has been identified. Fortunately, recent studies demonstrated a normalization of the cardiac biomarkers and the functional alterations within a short time frame. Therefore, these alterations may be perceived as physiological myocardial reactions to the strenuous exercise and the term 'cardiac fatigue' has been coined. This interpretation is supported by a recent analysis of 10.9 million marathon runners demonstrating that there was no significantly increased overall risk of cardiac arrest during long-distance running races. In conclusion, intensive and long-lasting EE, e.g. running a full-distance Marathon, results in high cardiovascular strain whose clinical relevance especially for middle-aged and older athletes is unclear and remains a matter of controversy. Furthermore, there is a need for evidence-based recommendations with respect to medical screening and training strategies especially in male amateur runners over the age of

  4. Ozone and cardiovascular injury

    Directory of Open Access Journals (Sweden)

    Rainaldi Giuseppe

    2009-06-01

    Full Text Available Abstract Air pollution is increasingly recognized as an important and modifiable determinant of cardiovascular diseases in urban communities. The potential detrimental effects are both acute and chronic having a strong impact on morbidity and mortality. The acute exposure to pollutants has been linked to adverse cardiovascular events such as myocardial infarction, heart failure and life-threatening arrhythmias. The long-terms effects are related to the lifetime risk of death from cardiac causes. The WHO estimates that air pollution is responsible for 3 million premature deaths each year. The evidence supporting these data is very strong nonetheless, epidemiologic and observational data have the main limitation of imprecise measurements. Moreover, the lack of clinical experimental models makes it difficult to demonstrate the individual risk. The other limitation is related to the lack of a clear mechanism explaining the effects of pollution on cardiovascular mortality. In the present review we will explore the epidemiological, clinical and experimental evidence of the effects of ozone on cardiovascular diseases. The pathophysiologic consequences of air pollutant exposures have been extensively investigated in pulmonary systems, and it is clear that some of the major components of air pollution (e.g. ozone and particulate matter can initiate and exacerbate lung disease in humans 1. It is possible that pulmonary oxidant stress mediated by particulate matter and/or ozone (O3 exposure can result in downstream perturbations in the cardiovasculature, as the pulmonary and cardiovascular systems are intricately associated, and it is well documented that specific environmental toxins (such as tobacco smoke 2 introduced through the lungs can initiate and/or accelerate cardiovascular disease development. Indeed, several epidemiologic studies have proved that there is an association between PM and O3 and the increased incidence of cardiovascular morbidity

  5. Understanding Adherence to 5 Servings of Fruits and Vegetables per Day: A Theory of Planned Behavior Perspective

    Science.gov (United States)

    Blanchard, Chris M.; Fisher, Janet; Sparling, Phillip B.; Shanks, Tiffany Hunt; Nehl, Eric; Rhodes, Ryan E.; Courneya, Kerry S.; Baker, Frank

    2009-01-01

    Objective: The primary purpose of the present study was to examine the utility of the Theory of Planned Behavior (TPB) in explaining the 5-A-Day intentions and behavior of college students. A secondary purpose was to determine whether any of the TPB relationships were moderated by gender or ethnicity. Design: A prospective design that asked…

  6. [Cardiovascular disease in pregnancy].

    Science.gov (United States)

    Hilfiker-Kleiner, Denise; Bauersachs, Johann

    2016-01-01

    Cardiovascular diseases are among the most frequent complications in pregnancies. Among them preexisting heart diseases including congenital heart disease, genetic cardiomyopathies, myocardial infarction and chemotherapy-induced cardiomyopathies display a special challenge for the mother and her physicians. Moreover, the incidence of cardiovascular disease induced by or associated with pregnancy, i.e. hypertensive disorders and peripartum cardiomyopathies, has increased over the past decades. In the present overview we explain why pregnancy is a stress model for the maternal heart and summarize the current knowledge on the influence of pregnancy on preexisting cardiomyopathies. We highlight recent advances in research with regard to hypertensive complications in pregnancy and peripartum cardiomyopathy (PPCM). Moreover, we summarize etiologies, risk factors, pathomechanisms, diagnosis, treatment, management and prognosis. Finally, interdisciplinarity between different clinical fields and basic science is a key requirement to avoid longterm damage to the cardiovascular system induced by pregnancy associated impacts and with this improve women's health in general. PMID:26800071

  7. Pharmacogenomics and cardiovascular disease

    DEFF Research Database (Denmark)

    Weeke, Peter; Roden, Dan M

    2013-01-01

    Variability in drug responsiveness is a sine qua non of modern therapeutics, and the contribution of genomic variation is increasingly recognized. Investigating the genomic basis for variable responses to cardiovascular therapies has been a model for pharmacogenomics in general and has established...... resulted in changes to the product labels but also have led to development of initial clinical guidelines that consider how to facilitate incorporating genetic information to the bedside. This review summarizes the state of knowledge in cardiovascular pharmacogenomics and considers how variants described...

  8. Advancing cardiovascular tissue engineering

    Science.gov (United States)

    Truskey, George A.

    2016-01-01

    Cardiovascular tissue engineering offers the promise of biologically based repair of injured and damaged blood vessels, valves, and cardiac tissue. Major advances in cardiovascular tissue engineering over the past few years involve improved methods to promote the establishment and differentiation of induced pluripotent stem cells (iPSCs), scaffolds from decellularized tissue that may produce more highly differentiated tissues and advance clinical translation, improved methods to promote vascularization, and novel in vitro microphysiological systems to model normal and diseased tissue function. iPSC technology holds great promise, but robust methods are needed to further promote differentiation. Differentiation can be further enhanced with chemical, electrical, or mechanical stimuli. PMID:27303643

  9. [Cardiovascular complications of diabetes].

    Science.gov (United States)

    Nishio, Yoshihiko

    2015-12-01

    Several lines of epidemical evidence have shown that type 2 diabetes is the most important risk factor for cardiovascular diseases (CVD). It has been shown that the risk of primary prevention of CVD in patients with diabetes is equal to that of the secondary prevention in general population. In this manuscript, recent reports on the cardiac tests to detect the cardiovascular lesions will be reviewed. The data suggest that MDCT is a promising test even in the patients with diabetes. Furthermore, recent evidence of the treatment of diabetes with insulin or the drugs available recently such as DPP-4 inhibitors and SGLT-2 inhibitors will be reviewed. PMID:26666152

  10. Research in cardiovascular care

    DEFF Research Database (Denmark)

    Jaarsma, Tiny; Deaton, Christi; Fitzsimmons, Donna;

    2014-01-01

    To deliver optimal patient care, evidence-based care is advocated and research is needed to support health care staff of all disciplines in deciding which options to use in their daily practice. Due to the increasing complexity of cardiac care across the life span of patients combined...... of the body of knowledge that is needed to further improve cardiovascular care. In this paper, knowledge gaps in current research related to cardiovascular patient care are identified, upcoming challenges are explored and recommendations for future research are given....

  11. Resveratrol and Cardiovascular Diseases

    OpenAIRE

    Dominique Bonnefont-Rousselot

    2016-01-01

    The increased incidence of cardiovascular diseases (CVDs) has stimulated research for substances that could improve cardiovascular health. Among them, resveratrol (RES), a polyphenolic compound notably present in grapes and red wine, has been involved in the “French paradox”. RES is known for its antioxidant and anti-inflammatory properties and for its ability to upregulate endothelial NO synthase (eNOS). RES was able to scavenge •OH/O2•− and peroxyl radicals, which can limit the lipid peroxi...

  12. Within-individual increases in innovative behavior and creative, persuasion, and change self-efficacy over time: A social-cognitive theory perspective.

    Science.gov (United States)

    Ng, Thomas W H; Lucianetti, Lorenzo

    2016-01-01

    Studies of innovative behavior (the generation, dissemination, and implementation of new ideas) have generally overlooked the agency perspective on this important type of performance behavior. Guided by social-cognitive theory, we propose a moderated mediation relationship to explain why and how employees become motivated to make things happen through their innovative endeavors. First, we propose that within-individual increases in organizational trust and perceived respect by colleagues promote within-individual increases in creative, persuasion, and change self-efficacy over time. Second, we propose that within-individual increases in self-efficacy beliefs promote within-individual increases in idea generation, dissemination, and implementation over time. Finally, we propose that psychological collectivism (a between-individual variable) is a moderator, and that a higher level of psychological collectivism weakens the positive relationship between within-individual increases in self-efficacy beliefs and within-individual increases in innovative behavior. Repeated measures collected from 267 employees in Italy at 3 time points over an 8-month period generally support our proposed dynamic moderated mediation relationship. PMID:26052714

  13. Review of Pedestrian Violating Behavior:A Theoretical Perspective%行人违规行为研究:一个理论综述

    Institute of Scientific and Technical Information of China (English)

    曹慧娟; 古仁华; 姚舒仪

    2015-01-01

    This paper reviews the study in the area of pedestrians ’ irregularities from different theoretical perspectives , in-cluding Theory of Planned Behavior , Game Theory , Motivation Theory and Threshold Model .The review evaluates and com-pares these theories applied to pedestrians ’ violating behavior about each advantages and deficiencies .Results indicate that Theory of Planned Behavior is the most widely used .Finally, this paper also discusses their further researches .%拟就几大主要理论在行人交通违规行为领域的运用作一个梳理和评述。从不同的理论视角对已有的研究进行了较为深入的综述,包括计划行为理论视角、博弈论视角、激励理论视角、阈值模型视角,并比较和评估了上述的行人违规行为理论模型,分析了各个视角的优势与不足,同时对深入研究进行了展望。

  14. Obesidade infantil e fatores de risco cardiovasculares

    OpenAIRE

    João Marcelo de Queiroz Miranda; Elisabete de Marco Ornelas; Rogério Brandão Wichi

    2011-01-01

    Introduction: Obesity is a disease of increasing prevalence, which currently assumes an epidemic main public health problem in contemporary society. Stems from genetic, behavioral, environmental, and can start at any age. However when it comes within the first years of life, predisposing to its presence at older ages and is associated with various comorbidities. Objective: To review the literature on the etiology of childhood obesity and to identify major cardiovascular risk factors associate...

  15. Brain, Behavior, and Immunity: Effects and potential mechanisms of exercise training on cancer progression: A translational perspective

    Science.gov (United States)

    Review of the extant epidemiological evidence examining the association between exercise behavior, function capacity/exercise capacity, and cancer-specific recurrence and mortality as well as all-cause mortality individuals following a cancer diagnosis.

  16. Physical activity, obesity and cardiovascular diseases.

    Science.gov (United States)

    Lakka, T A; Bouchard, C

    2005-01-01

    Sedentary lifestyle and overweight are major public health, clinical, and economical problems in modern societies. The worldwide epidemic of excess weight is due to imbalance between physical activity and dietary energy intake. Sedentary lifestyle, unhealthy diet, and consequent overweight and obesity markedly increase the risk of cardiovascular diseases. Regular physical activity 45-60 min per day prevents unhealthy weight gain and obesity, whereas sedentary behaviors such as watching television promote them. Regular exercise can markedly reduce body weight and fat mass without dietary caloric restriction in overweight individuals. An increase in total energy expenditure appears to be the most important determinant of successful exercise-induced weight loss. The best long-term results may be achieved when physical activity produces an energy expenditure of at least 2,500 kcal/week. Yet, the optimal approach in weight reduction programs appears to be a combination of regular physical activity and caloric restriction. A minimum of 60 min, but most likely 80-90 min of moderate-intensity physical activity per day may be needed to avoid or limit weight regain in formerly overweight or obese individuals. Regular moderate intensity physical activity, a healthy diet, and avoiding unhealthy weight gain are effective and safe ways to prevent and treat cardiovascular diseases and to reduce premature mortality in all population groups. Although the efforts to promote cardiovascular health concern the whole population, particular attention should be paid to individuals who are physically inactive, have unhealthy diets or are prone to weight gain. They have the highest risk for worsening of the cardiovascular risk factor profile and for cardiovascular disease. To combat the epidemic of overweight and to improve cardiovascular health at a population level, it is important to develop strategies to increase habitual physical activity and to prevent overweight and obesity in

  17. Study of large shareholders’ behavior after non-tradable shares reform: A perspective of related party transactions

    OpenAIRE

    Hongbo Zhang; Qing Xia

    2013-01-01

    Purpose: This paper explores the behavior choice of large shareholders in the related party transactions which occur between the large shareholders and listed companies by using the data of shares from 2007 to 2010. Design/methodology/appraoch: Based on the classical research paradigm (that is, LLSV), we analysis controlling shareholders’ propping and tunneling behaviors aiming to make sure their impacts to the medium and small shareholders in theory. Findings: We get the following findings: ...

  18. Cheese and cardiovascular health

    DEFF Research Database (Denmark)

    Hjerpsted, Julie Bousgaard

    Cardiovascular diseases (CVDs) are the number one cause of mortality worldwide. Low-density lipoprotein (LDL) cholesterol is a well-known risk factor of CVD which increases after the intake of saturated fatty acids (SFA). Cheese is a dietary product commonly consumed in Western countries and known...

  19. Epigenetics and cardiovascular disease

    Science.gov (United States)

    Despite advances in the prevention and management of cardiovascular disease (CVD), this group of multifactorial disorders remains a leading cause of mortality worldwide. CVD is associated with multiple genetic and modifiable risk factors; however, known environmental and genetic influences can only...

  20. Cardiovascular Disease Prevention Strategies

    NARCIS (Netherlands)

    R.L. Nijhuis (Rogier)

    2004-01-01

    textabstractWhereas secondary prevention of cardiovascular events through risk factor modification in patients with known coronary and carotid artery disease is recognised as cost-effective, CVD prevention by drug therapy in asymptomatic individuals has shown only modest benefits and to be relativel

  1. Religion, spirituality and cardiovascular disease: research, clinical implications, and opportunities in Brazil Religião, espiritualidade e doença cardiovascular: pesquisa, implicações clínicas e oportunidades no Brasil

    Directory of Open Access Journals (Sweden)

    Fernando A. Lucchese

    2013-03-01

    Full Text Available In this paper we comprehensively review published quantitative research on the relationship between religion, spirituality (R/S, and cardiovascular (CV disease, discuss mechanisms that help explain the associations reported, examine the clinical implications of those findings, and explore future research needed in Brazil on this topic. First, we define the terms religion, spirituality, and secular humanism. Next, we review research examining the relationships between R/S and CV risk factors (smoking, alcohol/drug use, physical inactivity, poor diet, cholesterol, obesity, diabetes, blood pressure, and psychosocial stress. We then review research on R/S, cardiovascular functions (CV reactivity, heart rate variability, etc., and inflammatory markers (IL-6, IFN-γ, CRP, fibrinogen, IL-4, IL-10. Next we examine research on R/S and coronary artery disease, hypertension, stroke, dementia, cardiac surgery outcomes, and mortality (CV mortality in particular. We then discuss mechanisms that help explain these relationships (focusing on psychological, social, and behavioral pathways and present a theoretical causal model based on a Western religious perspective. Next we discuss the clinical applications of the research, and make practical suggestions on how cardiologists and cardiac surgeons can sensitively and sensibly address spiritual issues in clinical practice. Finally, we explore opportunities for future research. No research on R/S and cardiovascular disease has yet been published from Brazil, despite the tremendous interest and involvement of the population in R/S, making this an area of almost unlimited possibilities for researchers in Brazil.

  2. Diet and Physical Activity for Cardiovascular Disease Prevention.

    Science.gov (United States)

    Lanier, Jeffrey B; Bury, David C; Richardson, Sean W

    2016-06-01

    Cardiovascular disease (CVD) is the leading cause of death in the United States. One-third of these deaths may be preventable through healthy lifestyle choices including diet and physical activity. The Mediterranean diet is associated with reduced cardiovascular mortality, whereas the Dietary Approaches to Stop Hypertension (DASH) eating plan is associated with a reduced risk of coronary artery disease. Substituting dietary saturated fat with polyunsaturated fatty acids is associated with improved cardiovascular outcomes, although exogenous supplementation with omega-3 fatty acids does not improve cardiovascular outcomes. There is an association between increased sodium intake and cardiovascular risk, but reducing dietary sodium has not consistently shown a reduction in cardiovascular risk. Physical activity recommendations for adults are at least 150 minutes of moderate-intensity aerobic activity per week, 75 minutes of vigorous-intensity aerobic activity per week, or an equivalent combination. Increases in physical activity by any level are associated with reduced cardiovascular risk. Introducing muscle-strengthening activities at least twice per week in previously inactive adults is associated with improved cardiovascular outcomes. Inactive adults without known CVD can gradually increase activity to a moderate-intensity level without consulting a physician. The U.S. Preventive Services Task Force recommends behavioral counseling to promote healthy diet and physical activity in adults at high risk of CVD. Evidence of benefit for counseling patients at average risk is less established. PMID:27281836

  3. Detection of Cardiovascular Anomalies: An Observer-Based Approach

    KAUST Repository

    Ledezma, Fernando

    2012-07-01

    In this thesis, a methodology for the detection of anomalies in the cardiovascular system is presented. The cardiovascular system is one of the most fascinating and complex physiological systems. Nowadays, cardiovascular diseases constitute one of the most important causes of mortality in the world. For instance, an estimate of 17.3 million people died in 2008 from cardiovascular diseases. Therefore, many studies have been devoted to modeling the cardiovascular system in order to better understand its behavior and find new reliable diagnosis techniques. The lumped parameter model of the cardiovascular system proposed in [1] is restructured using a hybrid systems approach in order to include a discrete input vector that represents the influence of the mitral and aortic valves in the different phases of the cardiac cycle. Parting from this model, a Taylor expansion around the nominal values of a vector of parameters is conducted. This expansion serves as the foundation for a component fault detection process to detect changes in the physiological parameters of the cardiovascular system which could be associated with cardiovascular anomalies such as atherosclerosis, aneurysm, high blood pressure, etc. An Extended Kalman Filter is used in order to achieve a joint estimation of the state vector and the changes in the considered parameters. Finally, a bank of filters is, as in [2], used in order to detect the appearance of heart valve diseases, particularly stenosis and regurgitation. The first numerical results obtained are presented.

  4. Cardiovascular molecular imaging of apoptosis

    Energy Technology Data Exchange (ETDEWEB)

    Wolters, S.L.; Reutelingsperger, C.P.M. [Maastricht University, Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht (Netherlands); Corsten, M.F.; Hofstra, L. [Maastricht University, Department of Cardiology, Cardiovascular Research Institute Maastricht, P.O. Box 616, Maastricht (Netherlands); Narula, J. [University of California Irvine, Department of Cardiology, Irvine (United States)

    2007-06-15

    Molecular imaging strives to visualise processes at the molecular and cellular level in vivo. Understanding these processes supports diagnosis and evaluation of therapeutic efficacy on an individual basis and thereby makes personalised medicine possible. Apoptosis is a well-organised mode of cell suicide that plays a role in cardiovascular diseases (CVD). Apoptosis is associated with loss of cardiomyocytes following myocardial infarction, atherosclerotic plaque instability, congestive heart failure and allograft rejection of the transplanted heart. Thus, apoptosis constitutes an attractive target for molecular imaging of CVD. Our current knowledge about the molecular players and mechanisms underlying apoptosis offers a rich palette of potential molecular targets for molecular imaging. However, only a few have been successfully developed so far. This review highlights aspects of the molecular machinery and biochemistry of apoptosis relevant to the development of molecular imaging probes. It surveys the role of apoptosis in four major areas of CVD and portrays the importance and future perspectives of apoptosis imaging. The annexin A5 imaging protocol is emphasised since it is the most advanced protocol to measure apoptosis in both preclinical and clinical studies. (orig.)

  5. Childhood obesity and cardiovascular disease

    OpenAIRE

    Bridger, Tracey

    2009-01-01

    Childhood obesity has reached epidemic proportions. Many of these children have risk factors for later disease, including cardiovascular disease. For optimal cardiovascular health, health care professionals must be able to identify children and youth at risk and provide appropriate support as needed. The present article reviews the current medical literature on obesity and cardiovascular disease risk factors in the paediatric population, the long-term cardiovascular consequences of childhood ...

  6. Improving the quality of cardiovascular preventive care in general practice

    OpenAIRE

    Lobo, Claudia

    2002-01-01

    textabstractIn this thesis we target cardiovascular preventive care from a continuous quality improvement point of view in a project called CARPE (CArdiovascular Risk reduction in Primary carE). We created a multifaceted intervention based on a ·quality cycle· and used outreach visitors for its implementation, since this approach has proven successful in modifying professional behavior. 13 In addressing prevention we considered Donebedian's model 14 to assess quality of care: i.e. we distingu...

  7. Nonfasting hyperlipidemia and cardiovascular disease

    DEFF Research Database (Denmark)

    Nordestgaard, B G; Langsted, A; Freiberg, J J

    2009-01-01

    , total cholesterol/HDL cholesterol, and apolipoprotein B/apolipoprotein A1 all associate with increased risk of cardiovascular disease. These new data open the possibility that nonfasting rather than fasting lipid profiles can be used for cardiovascular risk prediction. If implemented, this would...... of cardiovascular disease and early death....

  8. Hypertriglyceridemia and Cardiovascular Diseases: Revisited

    OpenAIRE

    Han, Seung Hwan; Nicholls, Stephen J.; Sakuma, Ichiro; Zhao, Dong; Koh, Kwang Kon

    2016-01-01

    Residual cardiovascular risk and failure of high density lipoprotein cholesterol raising treatment have refocused interest on targeting hypertriglyceridemia. Hypertriglyceridemia, triglyceride-rich lipoproteins, and remnant cholesterol have demonstrated to be important risk factors for cardiovascular disease; this has been demonstrated in experimental, genetic, and epidemiological studies. Fibrates can reduce cardiovascular event rates with or without statins. High dose omega-3 fatty acids co...

  9. Management of Cardiovascular Risk in Patients with Chronic Inflammatory Diseases

    DEFF Research Database (Denmark)

    Lindhardsen, Jesper; Kristensen, Søren Lund; Ahlehoff, Ole

    2016-01-01

    An increased risk of cardiovascular disease (CVD) has been observed in a range of chronic inflammatory diseases (CID), including rheumatoid arthritis (RA), psoriasis, inflammatory bowel diseases (IBD), and systemic lupus erythematosus (SLE). The increased risk of CVDs and reduced life expectancy in...... gained considerable interest in recent years. We briefly summarize the current level of evidence of the association between CIDs and CVD and cardiovascular risk management recommendations. Perspectives of ongoing and planned trials are discussed in consideration of potential ways to improve primary and...

  10. Study of large shareholders’ behavior after non-tradable shares reform: A perspective of related party transactions

    Directory of Open Access Journals (Sweden)

    Hongbo Zhang

    2013-09-01

    Full Text Available Purpose: This paper explores the behavior choice of large shareholders in the related party transactions which occur between the large shareholders and listed companies by using the data of shares from 2007 to 2010. Design/methodology/appraoch: Based on the classical research paradigm (that is, LLSV, we analysis controlling shareholders’ propping and tunneling behaviors aiming to make sure their impacts to the medium and small shareholders in theory. Findings: We get the following findings: After our capital market entering the era of full circulation, we find that the relationship between the ratio of controlling shareholders and the related party transactions present (RPTs an inverted “U” shape curve, which means that it exits a typical “Grab-synergy” effect. we should take different measures to the transactions occurred between the large shareholders and listed companies according to the property nature of the large shareholders. State-owned shareholders choose to realize their private benefits by means of RPTs, while the non state-owned shareholders conduct RPTs with an expectation of reducing costs.Practical implications: Since Guo Shuqing, the Chairman of China Securities Regulatory Commission, took office, he has taken a lot measures to curb the related party transactions harshly. Under this circumstance, it is just the right time to have a research on large shareholders’ behavior. It has important significance both in theory and practice. Originality/value: Considering the Chinese special national conditions, this paper added lots of comprehensive facts to study large shareholders’ behavior including the rate of the share held by indirect controller, the probability of thievish behaviors have been discovered, and the strict punishment regulations. The discussions in this paper help to bring into focus a highly topical issue within the context of the large shareholders’ behavior after Non-tradable Shares Reform.

  11. Predicting organizational citizenship behavior from the functional analysis and role identity perspectives: further evidence in Spanish employees.

    Science.gov (United States)

    Dávila, Ma Celeste; Finkelstein, Marcia A

    2010-05-01

    Organizational citizenship behavior (OCB) is a prosocial activity with similarities to volunteerism. The purpose of this work is to contribute new evidence about the relevance to OCB of two models of sustained volunteerism, functional analysis and role identity theory. A total of 983 Spanish employees at49 organizations completed surveys measuring amount of OCB, motives for engaging in citizenship behavior, and the degree to which respondents developed an organizational citizen role identity. The results showed that both motives and role identity were significant predictors of OCB, with motive partially mediating the role identity-OCB relationship. The findings suggest that similar mechanisms are involved in sustaining volunteerism and OCB. PMID:20480696

  12. Gene by Environment Research to Prevent Externalizing Problem Behavior : Ethical Questions Raised from a Public Healthcare Perspective

    NARCIS (Netherlands)

    Chhangur, Rabia R.; Weeland, Joyce; Matthys, Walter; Overbeek, Geertjan

    2015-01-01

    The main public health advantages of examining gene by environment interactions (i.e., G x E) in externalizing behavior lie in the realm of personalized interventions. Nevertheless, the incorporation of genetic data in randomized controlled trials is fraught with difficulties and raises ethical ques

  13. A Cross-Cultural Perspective of Parental Influence on Female Adolescents' Achievement Beliefs and Behaviors in Sport and School Domains

    Science.gov (United States)

    Bhalla, Jennifer A.; Weiss, Maureen R.

    2010-01-01

    Little is known about parental socialization processes for youth participants from different cultural backgrounds. The purpose of this study was to examine parental influence on self-perceptions, task values, and achievement behaviors among female adolescents from two cultures using Eccles' expectancy-value theory (Eccles et al., 1983). Twelve…

  14. The Impact of Health-Promoting Behaviors on Low-Income Children's Health: A Risk and Resilience Perspective

    Science.gov (United States)

    Yoo, Joan; Slack, Kristen S.; Holl, Jane L.

    2010-01-01

    This study's objective was to examine whether five child health-promoting behaviors by caregivers would be associated with caregivers' assessments of their children's health as "excellent," controlling for an array of risk factors for adverse health outcomes. The study used the third and fourth waves of the Illinois Families Study-Child Well-being…

  15. Risk Behaviors among Asian Women Who Work at Massage Parlors in San Francisco: Perspectives from Masseuses and Owners/Managers

    Science.gov (United States)

    Nemoto, Tooru; Iwamoto, Mariko; Oh, Hyun Joo; Wong, Serena; Nguyen, Hongmai

    2005-01-01

    This study investigates cognitive, cultural, and contextual factors that influence HIV-related risk behaviors among Asian women who engage in sex work at massage parlors in San Francisco. Focus groups and qualitative interviews were conducted for Vietnamese and Thai masseuses and massage parlor owners/managers. Economic pressure as well as…

  16. Slow breathing and cardiovascular disease

    Directory of Open Access Journals (Sweden)

    Ashish Chaddha

    2015-01-01

    Full Text Available Cardiovascular disease is the leading cause of death for both men and women worldwide. Much emphasis has been placed on the primary and secondary prevention of cardiovascular disease. While depression and anxiety increase the risk of developing cardiovascular disease, cardiovascular disease also increases the risk of developing anxiety and depression. Thus, promoting optimal mental health may be important for both primary and secondary prevention of cardiovascular disease. Like lowering blood pressure, lipids, and body weight, lowering anger and hostility and improving depression and anxiety may also be an important intervention in preventive cardiology. As we strive to further improve cardiovascular outcomes, the next bridge to cross may be one of offering patients nonpharmacologic means for combating daily mental stress and promoting mental health, such as yoga and pranayama. Indeed, the best preventive cardiovascular medicine may be a blend of both Western and Eastern medicine.

  17. Migraine and cardiovascular disease

    Directory of Open Access Journals (Sweden)

    Marcelo E. Bigal

    2011-02-01

    Full Text Available Migraine, especially migraine with aura is an established risk factor for ischemic lesions of the brain. Recent evidence has also linked migraine with and without aura to a broader range of ischemic vascular disorders including angina, myocardial infarction, coronary revascularization, claudication and cardiovascular mortality. The topic is therefore of considerable interest. Accordingly, herein we review the association between migraine and cardiovascular disease. We start by briefly presenting diagnostic criteria for migraine and revising its pathophysiology. We follow by summarizing the evidence on the topic. We then briefly present the results of a recent meta-analysis. We close by highlighting results of a large epidemiological study conducted after the publication of the meta-analysis.

  18. Prodrugs in Cardiovascular Therapy

    Directory of Open Access Journals (Sweden)

    Maryam Tabrizian

    2008-05-01

    Full Text Available Prodrugs are biologically inactive derivatives of an active drug intended to solve certain problems of the parent drug such as toxicity, instability, minimal solubility and non-targeting capabilities. The majority of drugs for cardiovascular diseases undergo firstpass metabolism, resulting in drug inactivation and generation of toxic metabolites, which makes them appealing targets for prodrug design. Since prodrugs undergo a chemical reaction to form the parent drug once inside the body, this makes them very effective in controlling the release of a variety of compounds to the targeted site. This review will provide the reader with an insight on the latest developments of prodrugs that are available for treating a variety of cardiovascular diseases. In addition, we will focus on several drug delivery methodologies that have merged with the prodrug approach to provide enhanced target specificity and controlled drug release with minimal side effects.

  19. Cardiovascular and interventional radiology

    International Nuclear Information System (INIS)

    This year's cardiovascular section demonstrates a continued growth in the number of digests on cardivascular and general interventional topics and continued progress in MRI studies. The reader will also notice fewer digests on DSA and percutaneous stone removal compared with the 1985 and 1986 Year Books. While newer technology, such as extracorporeal shock wave lithotripsy, has significantly reduced the number of percutaneous procedures for renal calculi, other interventional procedures, such as those involving fibrinolysis, are increasing by leaps and bounds. A number of digests on benign and malignant bile duct strictures continue to shed light on the management of these difficult cases. While abscess drainage is growing and well accepted by most surgeons, articles on esophageal dilatations seem to be declining in the radiology literature, probably on the basis of fewer operations being performed by us and more being performed by endoscopists. Digests on MRI in the cardiovascular system continue to report excellent images of the aorta and of congenital heart disease

  20. Cardiovascular: radioisotopic angiocardiography

    International Nuclear Information System (INIS)

    Radioisotopic angiocardiography, performed after the intravenous injection of 99/sup m/Tc-labeled pertechnetate or albumin, is a simple, rapid, and safe procedure which permits identification and physiologic assessment of a wide variety of congenital and acquired cardiovascular lesions in infants and children. These include atrial and ventricular septal defect, tetralogy of Fallot, pulmonic stenosis, aortopulmonary window, transposition of the great vessels, valvular stenosis and/or insufficiency, myocardial lesions, and lesions of the great vessels. The simplicity of the procedure lends itself to repeated measurements to assess the effects of therapy or to follow the course of the disease. A wide spectrum of congenital and acquired cardiovascular diseases have been studied which have particular application to the pediatric age group. (auth)

  1. Cardiovascular Molecular Imaging

    OpenAIRE

    Khanicheh, Elham

    2009-01-01

    Although there have been significant improvements in the treatment of cardiovascular diseases they still remain the main cause of morbidity and mortality globally. Currently available diagnostic approaches may not be adequate to detect pathologic changes during the early disease stages, which may be valuable for risk stratification and also to assess a response to a therapy. Therefore molecular imaging techniques such as Contrast Enhanced Ultrasound (CEU) molecular imaging to noninvasively i...

  2. Cardiovascular safety of etoricoxib

    Directory of Open Access Journals (Sweden)

    Viktoriya Georgievna Barskova

    2011-09-01

    Full Text Available Meticulous attention is paid to the cardiovascular safety of nonsteroidal anti-inflammatory drugs (NSAIDs, the so-called selective cyclooxy-genase 2 (COX-2 inhibitors in particular. The author considers precisely this matter in case of Russia's recent NSAID etoricoxib that has been tested along with other most studied medications from this group, by applying one of the latest meta-analyses. The EULAR recommendations to use NSAIDs are given.

  3. Modelling cardiovascular disease prevention

    OpenAIRE

    Alimadad, Azadeh

    2012-01-01

    According to the World Health Organization (WHO), cardiovascular disease (CVD), which sits under the chronic disease umbrella, is the number one cause of death globally. Over time, we have witnessed different trends that have influenced the prevalence of CVD. One of the ways of decreasing CVD and its social costs and global fatalities is through influencing preventable CVD risk factors. Though many risk factors such as age and gender are not preventable, there are several effective behaviours...

  4. A Regulatory Focus Perspective on Eating Behavior: How Prevention and Promotion Focus Relates to Emotional, External, and Restrained Eating

    Directory of Open Access Journals (Sweden)

    Stefan ePfattheicher

    2014-11-01

    Full Text Available By applying regulatory focus theory (RFT to the context of eating behavior, the present research examines the relations between individual differences in the two motivational orientations as conceptualized in RFT, that is, prevention-focused and promotion-focused self-regulation and emotional, external, and restrained eating. Building on a representative study conducted in the Netherlands (N = 4,230, it is documented that individual differences in prevention focus are positively related to emotional eating whereas negligible associations are found in regards to external and restrained eating. Individual differences in promotion focus are positively related to external eating whereas negligible associations are found in regards to emotional and restrained eating. In relating RFT to different eating styles we were able to document significant relations of basic self-regulatory orientations with regard to essential daily behavior associated with health and well-being. The implications for changing eating styles are discussed.

  5. A unified theoretical framework for understanding suicidal and self-harming behavior: Synthesis of diverging definitions and perspectives

    OpenAIRE

    Liljedahl, Sophie; Westling, Sofie

    2014-01-01

    Borderline Personality Disorder (BPD) has largely been associated with self-harm and chronic suicidality, despite the fact that these behaviours comprise only one diagnostic criterion. Treatments for self-harm are mostly indicated for individuals with BPD. Emerging literature suggests that youth with histories of depression are at risk of both self-harm and completed suicide. For individuals with repeated self-harm, co-occurring suicidal ideation and behavior is not uncommon. In the field of ...

  6. The Influences of Perceived Factors on Consumer Purchasing Behavior: In the Perspective of Online Shopping Capability of Consumers

    OpenAIRE

    Yingcong Xu; Lu Long; Lingying Zhang; Wojie Tan

    2013-01-01

    In this study, firstly, based on related researches about consumer online purchasing behavior before, we proposed that there were some perceived factors that influence perceived value which has a direct impact on consumer’s online purchasing decision-making. Secondly, on the analysis for the antecedent of consumer perceived factors with online shopping, we proposed the definition of online shopping capability of consumer and try to explore what factors would affect consumers’ perceived value ...

  7. Oh baby! Motivation for healthy eating during parenthood transitions: a longitudinal examination with a theory of planned behavior perspective

    OpenAIRE

    Bassett-Gunter, Rebecca L; Levy-Milne, Ryna; Naylor, Patti Jean; Symons Downs, Danielle; Benoit, Cecilia; Warburton, Darren E R; Blanchard, Chris M; Rhodes, Ryan E

    2013-01-01

    Background Transitioning to parenthood is a major life event that may impact parents’ personal lifestyles, yet there is an absence of theory-based research examining the impact of parenthood on motives for dietary behaviour. As a result, we are unaware of the social cognitive variables that predict eating behaviour among those transitioning to parenthood. The purpose of the study was to examine eating behaviour motives across 12 months within the framework of the theory of planned behavior (T...

  8. Consumers' attitude and intention towards organic food purchase: An extension of theory of planned behavior in gender perspective

    OpenAIRE

    Irianto, Heru

    2015-01-01

    The objective of this research was to study the variables affecting the consumer attitude to buy organic food that in turn affects the purchasing intention. Theory of Planned Behavior (TPB) was used to explain this. The study variables include health consciousness, environmental consciousness, organic food price, attitude, subjective norm, intentions to purchase organic food and gender. Survey method was used, with the sample containing 200 respondents intending to purchase organic food in Su...

  9. Insights on the adsorption behavior of aromatics in MIL-47 and MIL-53 from a theoretical perspective

    OpenAIRE

    Vandichel, Matthias; Van der Mynsbrugge, Jeroen; Verstraelen, Toon; Maes, Michael; Alaerts, Luc; De Vos, Dirk; Waroquier, Michel; Van Speybroeck, Veronique

    2010-01-01

    Recently, the spectrum of nanoporous materials like zeolites and zeotype structures has been further expanded through the discovery of a new class of hybrid porous solids [1, 2]. Those materials, nowadays also known as metal organic frameworks or MOFs, consist of both inorganic and organic moieties. Certain MOFs exhibit a very interesting adsorption and even catalytic behavior. Within this contribution, we will mainly focus on adsorption and separation of aromatic species in MIL-47 and MI...

  10. A regulatory focus perspective on eating behavior: how prevention and promotion focus relates to emotional, external, and restrained eating

    OpenAIRE

    Pfattheicher, Stefan; Sassenrath, Claudia

    2014-01-01

    By applying regulatory focus theory (RFT) to the context of eating behavior, the present research examines the relations between individual differences in the two motivational orientations as conceptualized in RFT, that is, prevention-focused and promotion-focused self-regulation and emotional, external, and restrained eating. Building on a representative study conducted in the Netherlands (N = 4,230), it is documented that individual differences in prevention focus are positively related to ...

  11. Analysis on Consumption Behavior of Zhejiang Province’s Farmers from the Perspective of Their Income Increase

    OpenAIRE

    Yu, Hailin

    2013-01-01

    With rapid development of industrialization in Zhejiang Province, surplus rural labor forces move to the secondary and tertiary industries. Farmers of Zhejiang Province are no exception. They turn to industrial workers and their income source has great changes. Wage income becomes their major source of income. Accordingly, farmers’ consumption behavior has great changes. Apart from satisfying basic production and living demands, farmers start to pursue living quality and their life style te...

  12. Sexual Health Care, Sexual Behaviors and Functioning, and Female Genital Cutting: Perspectives From Somali Women Living in the United States.

    Science.gov (United States)

    Connor, Jennifer Jo; Hunt, Shanda; Finsaas, Megan; Ciesinski, Amanda; Ahmed, Amira; Robinson, Beatrice Bean E

    2016-01-01

    We investigated the sexual values, attitudes, and behaviors of 30 Somali female refugees living in a large metropolitan area of Minnesota by collecting exploratory sexual health information based on the components of the sexual health model-components posited to be essential aspects of healthy human sexuality. A Somali-born bilingual interviewer conducted the semistructured interviews in English or Somali; 22 participants chose to be interviewed in Somali. Interviews were translated, transcribed, and analyzed using descriptive statistics and thematic analyses. Our study findings highlighted a sexually conservative culture that values sexual intimacy, female and male sexual pleasure, and privacy in marriage; vaginal sexual intercourse as the only sanctioned sexual behavior; and the importance of Islamic religion in guiding sexual practices. Findings related to human immunodeficiency virus (HIV) revealed HIV testing at immigration, mixed attitudes toward condom use, and moderate knowledge about HIV transmission modes. Female genital cutting (FGC) was a pervasive factor affecting sexual functioning in Somali women, with attitudes about the controversial practice in transition. We recommend that health professionals take the initiative to discuss sexual health care and safer sex, sexual behaviors/functioning, and likely challenges to sexual health with Somali women--as they may be unlikely to broach these subjects without permission and considerable encouragement. PMID:26168010

  13. Progress and perspectives of the Brazilian scientific production in international journals in the field of motor behavior

    Directory of Open Access Journals (Sweden)

    Ana Paula Kogake Claudio

    2009-09-01

    Full Text Available In view of the fact that one of the key indicators of scientific production is the number of papers published in international journals, and of the apparent growing interest in the area of motor behavior, we conducted a survey of articles published by Brazilian researchers in this area over the last 10 years (1999-2008 in international journals rated “Qualis International-A” and “Qualis International-B” by CAPES. This quantification was performed to provide a qualified viewpoint regarding the profile of Brazilian scientific production of international repercussion in the area of motor behavior. Articles were identified using the Google Scholar, Pubmed, Science Direct, and Scopus search systems, with the search being restricted to characteristic terms involving motor behavior and to researchers associated with Brazilian universities. The results showed an increase in production over the last 5 years of the period studied, with the peak in 2006. In addition, Brazilian scientific production was concentrated in four public universities. These results suggest that in order to keep growing, the new groups should work in collaboration with productive laboratories, decentralizing the scientific production.

  14. A Synthetic Ecology Perspective: How Well Does Behavior of Model Organisms in the Laboratory Predict Microbial Activities in Natural Habitats?

    Science.gov (United States)

    Yu, Zheng; Krause, Sascha M B; Beck, David A C; Chistoserdova, Ludmila

    2016-01-01

    In this perspective article, we question how well model organisms, the ones that are easy to cultivate in the laboratory and that show robust growth and biomass accumulation, reflect the dynamics and interactions of microbial communities observed in nature. Today's -omics toolbox allows assessing the genomic potential of microbes in natural environments in a high-throughput fashion and at a strain-level resolution. However, understanding of the details of microbial activities and of the mechanistic bases of community function still requires experimental validation in simplified and fully controlled systems such as synthetic communities. We have studied methane utilization in Lake Washington sediment for a few decades and have identified a number of species genetically equipped for this activity. We have also identified co-occurring satellite species that appear to form functional communities together with the methanotrophs. Here, we compare experimental findings from manipulation of natural communities involved in metabolism of methane in this niche with findings from manipulation of synthetic communities assembled in the laboratory of species originating from the same study site, from very simple (two-species) to rather complex (50-species) synthetic communities. We observe some common trends in community dynamics between the two types of communities, toward representation of specific functional guilds. However, we also identify strong discrepancies between the dominant methane oxidizers in synthetic communities compared to natural communities, under similar incubation conditions. These findings highlight the challenges that exist in using the synthetic community approach to modeling dynamics and species interactions in natural communities. PMID:27379075

  15. Using Action Research and Peer Perspectives to Develop Technology That Facilitates Behavioral Change and Self-Management in COPD

    Directory of Open Access Journals (Sweden)

    Catherine McCabe

    2014-01-01

    Full Text Available Background. Behavioural change and self-management in patients with chronic illness may help to control symptoms, avoid rehospitalization, enhance quality of life, and decrease mortality and morbidity. Objective. Guided by action research principles and using mixed methods, the aim of this project was to develop peer based educational, motivational, and health-promoting peer based videos, using behavioural change principles, to support self-management in patients with COPD. Methods. Individuals (n=32 living with COPD at home and involved in two community based COPD support groups were invited to participate in this project. Focus group/individual interviews and a demographic questionnaire were used to collect data. Results. Analysis revealed 6 categories relevant to behavioural change which included self-management, support, symptoms, knowledge, rehabilitation, and technology. Participants commented that content needed to be specific, and videos needed to be shorter, to be tailored to severity of condition, to demonstrate “normal” activities, to be positive, and to ensure that content is culturally relevant. Conclusions. This study demonstrated that detailed analysis of patient perspectives and needs for self-management is essential and should underpin the development of any framework, materials, and technology. The action research design principles provided an effective framework for eliciting the data and applying it to technology and testing its relevance to the user.

  16. Cardiovascular involvement by osteosarcoma: an analysis of 20 patients

    Energy Technology Data Exchange (ETDEWEB)

    Yedururi, Sireesha; Morani, Ajaykumar C.; Gladish, Gregory W. [The University of Texas MD Anderson Cancer Center, Department of Diagnostic Radiology, Houston, TX (United States); Vallabhaneni, Srilakshmi [Medstar Harbor Hospital, Department of Internal Medicine, Baltimore, MD (United States); Anderson, Peter M. [Levine Children' s Hospital/Levine Cancer Institute, Department of Pediatrics Hematology/Oncology/BMT, Carolinas Healthcare System, Charlotte, NC (United States); Hughes, Dennis; Daw, Najat C. [The University of Texas MD Anderson Cancer Center, Division of Pediatrics, Houston, TX (United States); Wang, Wei-Lien [The University of Texas MD Anderson Cancer Center, Department of Pathology, Houston, TX (United States)

    2016-01-15

    Although hematogenous spread of osteosarcoma is well known, the imaging findings of cardiovascular involvement by osteosarcoma are seldom reported and can be difficult to recognize. The enhanced resolution of modern CT and MRI scanners may lead to better detection of cardiovascular involvement. To describe the key imaging findings and clinical behavior of cardiovascular involvement by osteosarcoma. We retrospectively reviewed the imaging findings and clinical characteristics of 20 patients with cardiovascular involvement by osteosarcoma identified by two pediatric radiologists from a review of imaging studies at our institution from 2007 to 2013. At initial diagnosis, the median age of the patients was 15.1 years (range 4.8-24.6 years), and 7 (35%) patients had detectable metastases. Median time to detection of cardiovascular metastases was 1.8 years (range 0-7.3 years). Sixteen patients died of disease; 4 have survived a median of 7.4 years since initial diagnosis. The sites of cardiovascular involvement were the systemic veins draining the primary and metastatic osteosarcoma, pulmonary arteries, pulmonary veins draining the pulmonary metastases, and heart. A dilated and mineralized terminal pulmonary arteriole is an early sign of metastatic osteosarcoma in the lung. Unfamiliarity with the imaging features resulted in under-recognition and misinterpretation of intravascular tumor thrombus as bland thrombus. Knowledge of imaging findings in the era of modern imaging modalities has enhanced our ability to detect cardiovascular involvement and lung metastases early and avoid misinterpreting tumor thrombus in draining systemic veins or pulmonary arteries as bland thrombus. (orig.)

  17. Cardiovascular Risk Factors and Cardiovascular Hyperreactivity in Young Venezuelans

    OpenAIRE

    Sady Montes Amador; Mikhail Benet Rodríguez; Lenia Ramos Rodríguez; Esther Cano Andino; Erick Andrés Pérez Martín

    2015-01-01

    Background: cardiovascular hyperreactivity in young people has been associated with different risk factors and a family history of hypertension. Objective: to determine the association between a family history of hypertension and cardiovascular risk factors with cardiovascular hyperreactivity. Method: a correlational, cross-sectional study was conducted in a universe of 77 young individuals aged 18 to 40 years from the Churuguara parish of the Falcon State in Venezuela. The variables were: ag...

  18. The Influence of Interactivity Features of Databases on Scientific Behavior: A user perspective survey based on the Flow theory

    Directory of Open Access Journals (Sweden)

    Rahmatollah Fatthai

    2014-02-01

    Full Text Available We followed two aims: testing the effects of databases' user interface interactivity (UII on Scientific Behavior (SB and exploring the flow experience (FE as mediator between interface interactivity and SB, as well as self-efficacy (SE role as an interferer. We used mixed method in this research. We made a SB questionnaire via a comparative literature study, FE and user UII through literature review. Faculty members and PhD students participated as scholars. Structural Equation Modeling was used for quantitative data analysis and interpretative approach to analyze qualitative data. The role of typological variables, such as gender, area of study, academic degree and English language skill level on SE, UII, FE and SB means are investigated. Finally, we tested the effects of databases' UII on SB and mediator role of FE and interfering role of SE. We found that the more self-efficient participants, the more they experience user interface interactivity and scientific behavior changes/adaptations. In other words, self-efficacy is an important characteristic to establish interactive search session and to upgrade scientific behavior in scholars. Also, we found those participants who experience more flow, have more chance to experience SB changes and adaptation in UII environment. So UII may have effect on researchers' SB. Results may be used in: 1 distance education or researcher training, since these areas are interested in developing, changing and adapting SB; 2 Human-Computer Interaction field, because SB seems to be a new aspect of computer interaction effect on human; 3 The Flow theory will be supported by this new implementation. We proposed a new theoretical framework for research

  19. A novel approach to modeling and diagnosing the cardiovascular system

    Energy Technology Data Exchange (ETDEWEB)

    Keller, P.E.; Kangas, L.J.; Hashem, S.; Kouzes, R.T. [Pacific Northwest Lab., Richland, WA (United States); Allen, P.A. [Life Link, Richland, WA (United States)

    1995-07-01

    A novel approach to modeling and diagnosing the cardiovascular system is introduced. A model exhibits a subset of the dynamics of the cardiovascular behavior of an individual by using a recurrent artificial neural network. Potentially, a model will be incorporated into a cardiovascular diagnostic system. This approach is unique in that each cardiovascular model is developed from physiological measurements of an individual. Any differences between the modeled variables and the variables of an individual at a given time are used for diagnosis. This approach also exploits sensor fusion to optimize the utilization of biomedical sensors. The advantage of sensor fusion has been demonstrated in applications including control and diagnostics of mechanical and chemical processes.

  20. A synthetic ecology perspective: how well does behavior of model organisms in the laboratory predict microbial activities in natural habitats?

    Directory of Open Access Journals (Sweden)

    Zheng eYu

    2016-06-01

    Full Text Available In this perspective article we question how well model organisms, the ones that are easy to cultivate in the laboratory and that show robust growth and biomass accumulation, reflect the dynamics and interactions of microbial communities observed in nature. Today’s -omics toolbox allows assessing the genomic potential of microbes in natural environments in a high throughput fashion, and at a strain-level resolution. However, understanding of the details of microbial activities and of the mechanistic bases of community function still requires experimental validation in simplified and fully controlled systems such as synthetic communities. We have studied methane utilization in Lake Washington sediment for a few decades and have identified a number of species genetically equipped for this activity. We have also identified co-occurring satellite species that appear to form functional communities together with the methanotrophs. Here we compare experimental findings from manipulation of natural communities involved in metabolism of methane in this niche with findings from manipulation of synthetic communities assembled in the laboratory of species originating from the same study site, from very simple (two-species to rather complex (50-species synthetic communities. We observe some common trends in community dynamics between the two types of communities, toward representation of specific functional guilds. However, we also identify strong discrepancies between the dominant methane oxidizers in synthetic communities compared to natural communities, under similar incubation conditions. These findings highlight the challenges that exist in using the synthetic community approach to modeling dynamics and species interactions in natural communities.

  1. A Synthetic Ecology Perspective: How Well Does Behavior of Model Organisms in the Laboratory Predict Microbial Activities in Natural Habitats?

    Science.gov (United States)

    Yu, Zheng; Krause, Sascha M. B.; Beck, David A. C.; Chistoserdova, Ludmila

    2016-01-01

    In this perspective article, we question how well model organisms, the ones that are easy to cultivate in the laboratory and that show robust growth and biomass accumulation, reflect the dynamics and interactions of microbial communities observed in nature. Today’s -omics toolbox allows assessing the genomic potential of microbes in natural environments in a high-throughput fashion and at a strain-level resolution. However, understanding of the details of microbial activities and of the mechanistic bases of community function still requires experimental validation in simplified and fully controlled systems such as synthetic communities. We have studied methane utilization in Lake Washington sediment for a few decades and have identified a number of species genetically equipped for this activity. We have also identified co-occurring satellite species that appear to form functional communities together with the methanotrophs. Here, we compare experimental findings from manipulation of natural communities involved in metabolism of methane in this niche with findings from manipulation of synthetic communities assembled in the laboratory of species originating from the same study site, from very simple (two-species) to rather complex (50-species) synthetic communities. We observe some common trends in community dynamics between the two types of communities, toward representation of specific functional guilds. However, we also identify strong discrepancies between the dominant methane oxidizers in synthetic communities compared to natural communities, under similar incubation conditions. These findings highlight the challenges that exist in using the synthetic community approach to modeling dynamics and species interactions in natural communities. PMID:27379075

  2. Cardiovascular comorbidity in rheumatic diseases.

    Science.gov (United States)

    Nurmohamed, Michael T; Heslinga, Maaike; Kitas, George D

    2015-12-01

    Patients with rheumatoid arthritis (RA) and other inflammatory joint diseases (IJDs) have an increased risk of premature death compared with the general population, mainly because of the risk of cardiovascular disease, which is similar in patients with RA and in those with diabetes mellitus. Pathogenic mechanisms and clinical expression of cardiovascular comorbidities vary greatly between different rheumatic diseases, but atherosclerosis seems to be associated with all IJDs. Traditional risk factors such as age, gender, dyslipidaemia, hypertension, smoking, obesity and diabetes mellitus, together with inflammation, are the main contributors to the increased cardiovascular risk in patients with IJDs. Although cardiovascular risk assessment should be part of routine care in such patients, no disease-specific models are currently available for this purpose. The main pillars of cardiovascular risk reduction are pharmacological and nonpharmacological management of cardiovascular risk factors, as well as tight control of disease activity. PMID:26282082

  3. Nutrition and Cardiovascular Disease: Finding the Perfect Recipe for Cardiovascular Health

    OpenAIRE

    Alice Ravera; Valentina Carubelli; Edoardo Sciatti; Ivano Bonadei; Elio Gorga; Dario Cani; Enrico Vizzardi; Marco Metra; Carlo Lombardi

    2016-01-01

    The increasing burden of cardiovascular disease (CVD) despite the progress in management entails the need of more effective preventive and curative strategies. As dietary-associated risk is the most important behavioral factor influencing global health, it appears the best target in the challenge against CVD. Although for many years, since the formulation of the cholesterol hypothesis, a nutrient-based approach was attempted for CVD prevention and treatment, in recent years a dietary-based ap...

  4. Cardiovascular determinants of life span

    OpenAIRE

    Shi, Y; Camici, G G; Lüscher, T. F.

    2010-01-01

    The prevalence of cardiovascular diseases rises with aging and is one of the main causes of mortality in western countries. In view of the progressively aging population, there is an urge for a better understanding of age-associated cardiovascular diseases and its underlying molecular mechanisms. The risk factors for cardiovascular diseases include unhealthy diet, diabetes, obesity, smoking, alcohol consumption, physical inactivity, and aging. Increased production of oxygen-derived free radic...

  5. Traffic noise and cardiovascular disease

    OpenAIRE

    Selander, Jenny

    2010-01-01

    Traffic noise is an increasing problem in urban areas worldwide, but health effects in relation to traffic noise exposure are not well understood. Several studies show that noise may give rise to acute stress reactions, possibly leading to cardiovascular effects, but the evidence is limited on cardiovascular risks associated with traffic noise exposure. Cardiovascular effects have been indicated for other environmental stressors such as occupational noise exposure and job ...

  6. Periodontitis and cardiovascular disease.

    Science.gov (United States)

    Jeftha, A; Holmes, H

    2013-03-01

    Periodontal medicine has been studied and reviewed extensively since its introduction to the dental fraternity. The association of periodontal disease with and its effects on the cardiovascular system are amongst the many topics explored. A summary of the research into these associations and the possible mechanisms of any relationship is presented. Although a link between these two chronic inflammatory diseases is evident, the very heterogeneity of the relevant studies has not provided evidence sufficient to support an actual causal relationship. More stringent epidemiologic and intervention studies are required. PMID:23951765

  7. [Hyperuricemia, gout and cardiovascular diseases].

    Science.gov (United States)

    Murray, Karsten; Burkard, Thilo

    2016-01-01

    Hyperuricemia, gout as well as arterial hypertension and metabolic syndrom are highly prevalent and clinicians are frequently confronted with both conditions in the same patient. Hyperuricemia and gout are associated with cardiovascular comorbidities and a high cardiovascular risk. Despite coherent pathophysiological concepts, it remains to be determined, if this association is independent and causal. In daily clinical practice, cardiovascular risk factors should be thoroughly identified and consequently treated in all patients with hyperuricemia and gout. If preventive treatment of asymptomatic hyperuricemia with urate-lowering agents may improve cardiovascular risk and outcomes remains to be determined and is recommended only in special situations like young patients with severe hyperuricemia. PMID:27008446

  8. Oxidative Stress in Cardiovascular Disease

    Directory of Open Access Journals (Sweden)

    Gábor Csányi

    2014-04-01

    Full Text Available In the special issue “Oxidative Stress in Cardiovascular Disease” authors were invited to submit papers that investigate key questions in the field of cardiovascular free radical biology. The original research articles included in this issue provide important information regarding novel aspects of reactive oxygen species (ROS-mediated signaling, which have important implications in physiological and pathophysiological cardiovascular processes. The issue also included a number of review articles that highlight areas of intense research in the fields of free radical biology and cardiovascular medicine.

  9. Analysis on Consumption Behavior of Zhejiang Province’s Farmers from the Perspective of Their Income Increase

    Institute of Scientific and Technical Information of China (English)

    Hailin; YU

    2013-01-01

    With rapid development of industrialization in Zhejiang Province, surplus rural labor forces move to the secondary and tertiary industries. Farmers of Zhejiang Province are no exception. They turn to industrial workers and their income source has great changes. Wage income becomes their major source of income. Accordingly, farmers’ consumption behavior has great changes. Apart from satisfying basic production and living demands, farmers start to pursue living quality and their life style tends to urbanization. Nevertheless, under the influence of rural physical environment, policies and systems, the existing consumption environment fails to follow farmers’ urban lifestyle any more. In line with how to optimize rural consumption environment, improve farmers’ consuming capacity, continue to expand farmers’ consumption and promote urbanization development of rural areas, this paper presents pertinent countermeasures and recommendations.

  10. When do business units benefit more from collective citizenship behavior of management teams? An upper echelons perspective.

    Science.gov (United States)

    Liu, Wu; Gong, Yaping; Liu, Jun

    2014-05-01

    Drawing upon the notion of managerial discretion from upper echelons theory, we theorize which external contingencies moderate the relationship between collective organizational citizenship behavior (COCB) and unit performance. Focusing on business unit (BU) management teams, we hypothesize that COCB of BU management teams enhances BU performance and that this impact depends on environmental uncertainty and BU management-team decision latitude, 2 determinants of managerial discretion. In particular, the positive effect of COCB is stronger when environmental uncertainty or the BU management-team decision latitude is greater. Time-lagged data from 109 BUs of a telecommunications company support the hypotheses. Additional exploratory analysis shows that the positive moderating effect of environmental uncertainty is further amplified at higher levels of BU management-team decision latitude. Overall, this study extends the internally focused view in the micro OCB literature by introducing external contingencies for the COCB-unit-performance relationship. PMID:24417551

  11. Mexican American women's perspectives on a culturally adapted cognitive-behavioral therapy guided self-help program for binge eating.

    Science.gov (United States)

    Shea, Munyi; Cachelin, Fary M; Gutierrez, Guadalupe; Wang, Sherry; Phimphasone, Phoutdavone

    2016-02-01

    The prevalence of bulimia nervosa (BN) and binge eating disorder (BED) among Latinas is comparable to those of the general population; however, few interventions and treatment trial research have focused on this group. Cognitive-behavioral therapy (CBT) is the treatment of choice for binge eating related disorders. CBT-based guided self-help (CBTgsh)-a low-cost minimal intervention-has also been shown effective in improving binge eating related symptom, but the effectiveness of the CBTgsh among ethnic minority women is not well understood. Cultural adaptation of evidence-based treatments can be an important step for promoting treatment accessibility and engagement among underserved groups. This qualitative study was part of a larger investigation that examined the feasibility and efficacy of a culturally adapted CBTgsh program among Mexican American women with binge eating disorders. Posttreatment focus groups were conducted with 12 Mexican American women with BN or BED who participated in the intervention. Data were analyzed with the grounded theory methodology (Corbin & Strauss, 2008). Three themes emerged from the data: (a) eating behavior and body ideals are socially and culturally constructed, (b) multifaceted support system is crucial to Mexican American women's treatment engagement and success, and (c) the culturally adapted CBTgsh program is feasible and relevant to Mexican American women's experience, but it can be strengthened with increased family and peer involvement. The findings provide suggestions for further adaptation and refinement of the CBTgsh, and implications for future research as well as early intervention for disordered eating in organized care settings. PMID:26462112

  12. Resveratrol and Cardiovascular Diseases

    Directory of Open Access Journals (Sweden)

    Dominique Bonnefont-Rousselot

    2016-05-01

    Full Text Available The increased incidence of cardiovascular diseases (CVDs has stimulated research for substances that could improve cardiovascular health. Among them, resveratrol (RES, a polyphenolic compound notably present in grapes and red wine, has been involved in the “French paradox”. RES is known for its antioxidant and anti-inflammatory properties and for its ability to upregulate endothelial NO synthase (eNOS. RES was able to scavenge •OH/O2•− and peroxyl radicals, which can limit the lipid peroxidation processes. Moreover, in bovine aortic endothelial cells (BAEC under glucose-induced oxidative stress, RES restored the activity of dimethylargininedimethylaminohydrolase (DDAH, an enzyme that degrades an endogenous inhibitor of eNOS named asymmetric dimethylarginine (ADMA. Thus, RES could improve •NO availability and decrease the endothelial dysfunction observed in diabetes. Preclinical studies have made it possible to identify molecular targets (SIRT-1, AMPK, Nrf2, NFκB…; however, there are limited human clinical trials, and difficulties in the interpretation of results arise from the use of high-dose RES supplements in research studies, whereas low RES concentrations are present in red wine. The discussions on potential beneficial effects of RES in CVDs (atherosclerosis, hypertension, stroke, myocardial infarction, heart failure should compare the results of preclinical studies with those of clinical trials.

  13. Cardiovascular benefits of exercise

    Directory of Open Access Journals (Sweden)

    Agarwal SK

    2012-06-01

    Full Text Available Shashi K AgarwalMedical Director, Agarwal Health Center, NJ, USAAbstract: Regular physical activity during leisure time has been shown to be associated with better health outcomes. The American Heart Association, the Centers for Disease Control and Prevention and the American College of Sports Medicine all recommend regular physical activity of moderate intensity for the prevention and complementary treatment of several diseases. The therapeutic role of exercise in maintaining good health and treating diseases is not new. The benefits of physical activity date back to Susruta, a 600 BC physician in India, who prescribed exercise to patients. Hippocrates (460–377 BC wrote “in order to remain healthy, the entire day should be devoted exclusively to ways and means of increasing one's strength and staying healthy, and the best way to do so is through physical exercise.” Plato (427–347 BC referred to medicine as a sister art to physical exercise while the noted ancient Greek physician Galen (129–217 AD penned several essays on aerobic fitness and strengthening muscles. This article briefly reviews the beneficial effects of physical activity on cardiovascular diseases.Keywords: exercise, cardiovascular disease, lifestyle changes, physical activity, good health

  14. Cardiovascular risk factors among Chamorros

    Directory of Open Access Journals (Sweden)

    Wu Phillis L

    2006-12-01

    Full Text Available Abstract Background Little is known regarding the cardiovascular disease risk factors among Chamorros residing in the United States. Methods The Chamorro Directory International and the CDC's Behavioral Risk Factor Surveillance System Questionnaire (BRFSS were used to assess the health related practices and needs of a random sample of 228 Chamorros. Results Inactivity, hypertension, elevated cholesterol and diabetes mellitus were more prevalent in this Chamorro sample compared to the US average. Participants who were 50-and-older or unemployed were more likely to report hypertension, diabetes and inactivity, but they were also more likely to consume more fruits and vegetables than their younger and employed counterparts. Women were more likely to report hypertension and diabetes, whereas men were more likely to have elevated BMI and to have never had their blood cholesterol checked. Conclusion The study provides data that will help healthcare providers, public health workers and community leaders identify where to focus their health improvement efforts for Chamorros and create culturally competent programs to promote health in this community.

  15. Describing an Academic and Nonprofit Organization Partnership to Educate At-Risk Adolescents about Cardiovascular Health

    Science.gov (United States)

    Palazzo, Steven J.; Skager, Cherie; Kraiger, Anneliese

    2014-01-01

    There is emerging evidence to suggest community-based interventions can change community-wide behaviors and attitudes toward cardiovascular health. This article describes a partnership between an academic institution and a community nonprofit organization to develop and implement a cardiovascular health promotion program targeting at risk high…

  16. Heavy Metal Poisoning and Cardiovascular Disease

    Directory of Open Access Journals (Sweden)

    Eman M. Alissa

    2011-01-01

    Full Text Available Cardiovascular disease (CVD is an increasing world health problem. Traditional risk factors fail to account for all deaths from CVD. It is mainly the environmental, dietary and lifestyle behavioral factors that are the control keys in the progress of this disease. The potential association between chronic heavy metal exposure, like arsenic, lead, cadmium, mercury, and CVD has been less well defined. The mechanism through which heavy metals act to increase cardiovascular risk factors may act still remains unknown, although impaired antioxidants metabolism and oxidative stress may play a role. However, the exact mechanism of CVD induced by heavy metals deserves further investigation either through animal experiments or through molecular and cellular studies. Furthermore, large-scale prospective studies with follow up on general populations using appropriate biomarkers and cardiovascular endpoints might be recommended to identify the factors that predispose to heavy metals toxicity in CVD. In this review, we will give a brief summary of heavy metals homeostasis, followed by a description of the available evidence for their link with CVD and the proposed mechanisms of action by which their toxic effects might be explained. Finally, suspected interactions between genetic, nutritional and environmental factors are discussed.

  17. Cheese and cardiovascular disease risk

    DEFF Research Database (Denmark)

    Hjerpsted, Julie Bousgaard; Tholstrup, Tine

    2016-01-01

    Abstract Currently, the effect of dairy products on cardiovascular risk is a topic with much debate and conflicting results. The purpose of this review is to give an overview of the existing literature regarding the effect of cheese intake and risk of cardiovascular disease (CVD). Studies included...

  18. Cardiovascular toxicities of biological therapies

    DEFF Research Database (Denmark)

    Ryberg, Marianne

    2013-01-01

    effects. One serious adverse effect is the risk of cardiovascular dysfunction. Some targeted therapies, eg, treatment with monoclonal antibodies or angiogenesis inhibitors, have shown an increased risk of cardiac events. Their influence on the cardiovascular system, however, seems to be transient, but...

  19. 股权集中度与企业自主创新行为:基于行为动机视角%Ownership Concentration and Corporation Indigenous Innovation Behavior:From the Perspective of Behavior Motivation

    Institute of Scientific and Technical Information of China (English)

    杨建君; 王婷; 刘林波

    2015-01-01

    以公司治理困境为切入点,讨论如何配置公司股权结构既能发挥股东的支持行为,又能增强经理人的主动性,最终促进企业自主创新行为。整合代理理论与行为动机理论,引入经理人创新动力作为中介变量,并将市场竞争程度和创新空间作为调节变量加入模型,探讨股权集中度对自主创新行为的作用路径,利用182家企业的调研数据进行模型检验。研究结果表明,股权集中度与经理人创新动力、自主创新行为之间都存在倒U形关系,股权集中度通过经理人创新动力间接影响自主创新行为,创新空间正向调节经理人创新动力与自主创新行为间的关系,且这一调节效应不影响经理人创新动力中介作用的发挥,市场竞争程度的调节作用并不显著。%Extant study exploring how corporate governance influences innovation mainly focuses on the perspective of owners ormanagers in an agent relationship, which may yield governance dilemma paid inadequate attention to previously .Thus, there existsa necessity to explore how to configure corporate ownership structure to stimulate owner ′s incentive effect as well as enhancemanager′s initiative so as to further facilitate corporation indigenous innovation behavior .Accordingly, it is deserved in-depth analysisof the internal influence mechanism of ownership concentration regarding managers as the breakthrough point .Inspired bythe aforementioned discussions, integrating agency theory, behavior-motivation theory, and innovation theory, this paper introducesmanager′s innovation motivation as mediating variable to link ownership concentration and corporation indigenous innova -tion behavior.Meanwhile, as it is held better to match inside enterprise environmental factors with the outside ones , this studyfurther introduces market competition and innovation space to analyze the moderated effect in the relationship of manager

  20. Risk of cardiovascular disease

    DEFF Research Database (Denmark)

    Gejl, Michael; Starup-Linde, Jakob; Thomsen, Jan Lykke Scheel;

    2015-01-01

    AIMS: Type 2 diabetes (DM) increases the risk of cardiovascular disease. We investigated the effects of antidiabetic drugs on the composite endpoint (CE) of ischemic heart disease, heart failure or stroke in DM patients. METHODS: We conducted a nested case-control study. Cases were DM patients who......% CI: 16.88-24.12), neuropathy (OR=1.39, 95% CI: 1.05-1.85) and peripheral artery disease (OR=1.31, 95% CI: 1.02-1.69) increased the risk of CE. Biguanides (OR=0.62 95% CI; 0.54-0.71) and liraglutide (OR=0.48 95% CI; 0.38-0.62) significantly decreased the risk of CE as did statin treatment (OR=0.63, 95...

  1. Cardiovascular complications of cirrhosis

    DEFF Research Database (Denmark)

    Møller, Søren; Henriksen, Jens Henrik

    2008-01-01

    without adequate plasma volume expansion, transjugular intrahepatic portosystemic shunt (TIPS) insertion, peritoneovenous shunting and surgery. Cardiac failure is an important cause of mortality after liver transplantation, but improved liver function has also been shown to reverse the cardiac......Cardiovascular complications of cirrhosis include cardiac dysfunction and abnormalities in the central, splanchnic and peripheral circulation, and haemodynamic changes caused by humoral and nervous dysregulation. Cirrhotic cardiomyopathy implies systolic and diastolic dysfunction and...... abnormalities. No specific treatment can be recommended, and cardiac failure should be treated as in non-cirrhotic patients with sodium restriction, diuretics, and oxygen therapy when necessary. Special care should be taken with the use of ACE inhibitors and angiotensin antagonists in these patients. The...

  2. Assessment of cardiovascular risk.

    LENUS (Irish Health Repository)

    Cooney, Marie Therese

    2010-10-01

    Atherosclerotic cardiovascular disease (CVD) is the most common cause of death worldwide. Usually atherosclerosis is caused by the combined effects of multiple risk factors. For this reason, most guidelines on the prevention of CVD stress the assessment of total CVD risk. The most intensive risk factor modification can then be directed towards the individuals who will derive the greatest benefit. To assist the clinician in calculating the effects of these multiple interacting risk factors, a number of risk estimation systems have been developed. This review address several issues regarding total CVD risk assessment: Why should total CVD risk be assessed? What risk estimation systems are available? How well do these systems estimate risk? What are the advantages and disadvantages of the current systems? What are the current limitations of risk estimation systems and how can they be resolved? What new developments have occurred in CVD risk estimation?

  3. Individual differences in cardiovascular response to social challenge

    NARCIS (Netherlands)

    Sgoifo, A; Costoli, T; Meerlo, P; Buwalda, B; Pico'Alfonso, MA; De Boer, S; Musso, E; Koolhaas, J

    2005-01-01

    An important determinant of cardiovascular stress reactivity and morbidity is the individual behavioral strategy of coping with social challenge. This review summarizes the results of a number of studies that we performed in rats, aimed at investigating the relationship between aggression and cardio

  4. Cardiovascular effects of basal insulins

    Directory of Open Access Journals (Sweden)

    Mannucci E

    2015-07-01

    Full Text Available Edoardo Mannucci,1 Stefano Giannini,2 Ilaria Dicembrini1 1Diabetes Agency, Careggi Teaching Hospital, Florence, 2Section of Endocrinology, Department of Biomedical Clinical and Experimental Sciences, University of Florence and Careggi University Hospital, Florence, Italy Abstract: Basal insulin is an important component of treatment for both type 1 and type 2 diabetes. One of the principal aims of treatment in patients with diabetes is the prevention of diabetic complications, including cardiovascular disease. There is some evidence, although controversial, that attainment of good glycemic control reduces long-term cardiovascular risk in both type 1 and type 2 diabetes. The aim of this review is to provide an overview of the potential cardiovascular safety of the different available preparations of basal insulin. Current basal insulin (neutral protamine Hagedorn [NPH], or isophane and basal insulin analogs (glargine, detemir, and the more recent degludec differ essentially by various measures of pharmacokinetic and pharmacodynamic effects in the bloodstream, presence and persistence of peak action, and within-subject variability in the glucose-lowering response. The currently available data show that basal insulin analogs have a lower risk of hypoglycemia than NPH human insulin, in both type 1 and type 2 diabetes, then excluding additional harmful effects on the cardiovascular system mediated by activation of the adrenergic system. Given that no biological rationale for a possible difference in cardiovascular effect of basal insulins has been proposed so far, available meta-analyses of publicly disclosed randomized controlled trials do not show any signal of increased risk of major cardiovascular events between the different basal insulin analogs. However, the number of available cardiovascular events in these trials is very small, preventing any clear-cut conclusion. The results of an ongoing clinical trial comparing glargine and degludec with

  5. Credit scores, cardiovascular disease risk, and human capital.

    Science.gov (United States)

    Israel, Salomon; Caspi, Avshalom; Belsky, Daniel W; Harrington, HonaLee; Hogan, Sean; Houts, Renate; Ramrakha, Sandhya; Sanders, Seth; Poulton, Richie; Moffitt, Terrie E

    2014-12-01

    Credit scores are the most widely used instruments to assess whether or not a person is a financial risk. Credit scoring has been so successful that it has expanded beyond lending and into our everyday lives, even to inform how insurers evaluate our health. The pervasive application of credit scoring has outpaced knowledge about why credit scores are such useful indicators of individual behavior. Here we test if the same factors that lead to poor credit scores also lead to poor health. Following the Dunedin (New Zealand) Longitudinal Study cohort of 1,037 study members, we examined the association between credit scores and cardiovascular disease risk and the underlying factors that account for this association. We find that credit scores are negatively correlated with cardiovascular disease risk. Variation in household income was not sufficient to account for this association. Rather, individual differences in human capital factors—educational attainment, cognitive ability, and self-control—predicted both credit scores and cardiovascular disease risk and accounted for ∼45% of the correlation between credit scores and cardiovascular disease risk. Tracing human capital factors back to their childhood antecedents revealed that the characteristic attitudes, behaviors, and competencies children develop in their first decade of life account for a significant portion (∼22%) of the link between credit scores and cardiovascular disease risk at midlife. We discuss the implications of these findings for policy debates about data privacy, financial literacy, and early childhood interventions. PMID:25404329

  6. Predicting health behaviors with time perspective among undergraduate of a comprehensive university in Beijing%北京某高校本科生饮食运动行为与时间观念关系分析

    Institute of Scientific and Technical Information of China (English)

    张璐; 钮文异

    2012-01-01

    目的 了解北京市某综合大学在校本科生饮食和运动相关行为及其与时间观念的关系,为促使大学生健康行为习惯的养成提供依据.方法 采用自行设计的饮食和运动行为调查问卷和津巴多时间观念量表,对北京某高校选修《健康的生活方式与健康传播》通选课的194名在校本科生进行调查.结果 健康行为与未来时间观念得分正相关,如吃早餐频率、吃水果与蔬菜的频率,参加体育锻炼频率及运动开销比例等,而健康危险行为则与其呈负相关关系,部分健康危险行为与享乐主义时间观和宿命主义的现在时间观得分呈正相关,健康行为与其呈正相关.而改变不良饮食/运动行为的意愿与现在时间观念得分呈负相关,与未来时间观念得分呈正相关.结论 时间观念在预测健康行为方面有着一定的意义;采取适当的影响时间观念的心理干预及健康教育措施来促进本科生形成和保持良好的饮食和运动行为习惯是很有必要的.%Objective To analyze the relation between dietary and sports behaviors and time perspective among undergraduate of a comprehensive university in Beijing, and to supply information to further promote healthy behaviors and healthy lifestyles among undergraduate students. Methods Totally 194 students who took the Healthy Lifestyle and Health Communication as elec-tives answered a self-administered questionnaire as well as Zimbardo Time Perspective Inventory. Afterwards, descriptive and uni-variate analysis were used to determine the current situation among the undergraduate from this university and the relation between time perspective and behaviors. Results A majority of undergraduate students involved in this investigation were implementing unhealthy behaviors and taking insufficient amount of exercise in their daily life. There was a significant correlation between some healthy behaviors and time perspective, and so does sports

  7. Urotensin II in cardiovascular regulation

    Directory of Open Access Journals (Sweden)

    Fraser D Russell

    2008-08-01

    Full Text Available Fraser D RussellSchool of Health and Sport Sciences, Faculty of Science, Health and Education, University of the Sunshine Coast, Sippy Downs, Queensland, AustraliaAbstract: Cardiovascular function is modulated by neuronal transmitters, circulating hormones, and factors that are released locally from tissues. Urotensin II (UII is an 11 amino acid peptide that stimulates its’ obligatory G protein coupled urotensin II receptors (UT to modulate cardiovascular function in humans and in other animal species, and has been implicated in both vasculoprotective and vasculopathic effects. For example, tissue and circulating concentrations of UII have been reported to increase in some studies involving patients with atherosclerosis, heart failure, hypertension, preeclampsia, diabetes, renal disease and liver disease, raising the possibility that the UT receptor system is involved in the development and/or progression of these conditions. Consistent with this hypothesis, administration of UT receptor antagonists to animal models of cardiovascular disease have revealed improvements in cardiovascular remodelling and hemodynamics. However, recent studies have questioned this contributory role of UII in disease, and have instead postulated a protective effect on the cardiovascular system. For example, high concentrations of circulating UII correlated with improved clinical outcomes in patients with renal disease or myocardial infarction. The purpose of this review is to consider the regulation of the cardiovascular system by UII, giving consideration to methodologies for measurement of plasma concentrations, sites of synthesis and triggers for release.Keywords: urotensin II, cardiovascular disease, heart failure, hypertension

  8. Urotensin II in cardiovascular regulation

    Directory of Open Access Journals (Sweden)

    Fraser D Russell

    2008-09-01

    Full Text Available Fraser D RussellSchool of Health and Sport Sciences, Faculty of Science, Health and Education, University of the Sunshine Coast, Sippy Downs, Queensland, AustraliaAbstract: Cardiovascular function is modulated by neuronal transmitters, circulating hormones, and factors that are released locally from tissues. Urotensin II (UII is an 11 amino acid peptide that stimulates its’ obligatory G protein coupled urotensin II receptors (UT to modulate cardiovascular function in humans and in other animal species, and has been implicated in both vasculoprotective and vasculopathic effects. For example, tissue and circulating concentrations of UII have been reported to increase in some studies involving patients with atherosclerosis, heart failure, hypertension, preeclampsia, diabetes, renal disease and liver disease, raising the possibility that the UT receptor system is involved in the development and/or progression of these conditions. Consistent with this hypothesis, administration of UT receptor antagonists to animal models of cardiovascular disease have revealed improvements in cardiovascular remodelling and hemodynamics. However, recent studies have questioned this contributory role of UII in disease, and have instead postulated a protective effect on the cardiovascular system. For example, high concentrations of circulating UII correlated with improved clinical outcomes in patients with renal disease or myocardial infarction. The purpose of this review is to consider the regulation of the cardiovascular system by UII, giving consideration to methodologies for measurement of plasma concentrations, sites of synthesis and triggers for release.Keywords: urotensin II, cardiovascular disease, heart failure, hypertension

  9. Prevalence of Cardiovascular disease risk among Medical Students in South India

    OpenAIRE

    Biswajit Paul; Vidhyaa Nayaaki; Mousumi Sen; Rita Isaac

    2015-01-01

    Background: Cardiovascular diseases (CVDs) are global epidemic and contribute to double burden in developing countries. Individual’s dietary habits and risk behavior influence the onset and progression of CVDs. Medical students are future role models of the society and their knowledge, habits and behavior can influence their practice in prevention of CVDs in general population. Aims & Objectives: To assess the prevalence of common cardiovascular risk factors among a sample of medical stud...

  10. Simulations of the Cardiovascular System Using the Cardiovascular Simulation Toolbox

    OpenAIRE

    Ortiz-León, Gabriela; Vílchez-Monge, Marta; Montero-Rodríguez, Juan J.

    2014-01-01

    In the present document, six mathematical models of the cardiovascular system are studied and implemented in MATLAB R2013a using an updated version of the Cardiovascular Simulation Toolbox proposed by O. Barnea at the Tel-Aviv University. All the mathematical models are based on electrical lumped-parameter analogies. The results of the simulations are compared with a list of expected hemodynamic parameters and contrasted with laboratory values.

  11. Cardiovascular MRI with ferumoxytol.

    Science.gov (United States)

    Finn, J P; Nguyen, K-L; Han, F; Zhou, Z; Salusky, I; Ayad, I; Hu, P

    2016-08-01

    The practice of contrast-enhanced magnetic resonance angiography (CEMRA) has changed significantly in the span of a decade. Concerns regarding gadolinium (Gd)-associated nephrogenic systemic fibrosis in those with severely impaired renal function spurred developments in low-dose CEMRA and non-contrast MRA as well as efforts to seek alternative MR contrast agents. Originally developed for MR imaging use, ferumoxytol (an ultra-small superparamagnetic iron oxide nanoparticle), is currently approved by the US Food and Drug Administration for the treatment of iron deficiency anaemia in adults with renal disease. Since its clinical availability in 2009, there has been rising interest in the scientific and clinical use of ferumoxytol as an MR contrast agent. The unique physicochemical and pharmacokinetic properties of ferumoxytol, including its long intravascular half-life and high r1 relaxivity, support a spectrum of MRI applications beyond the scope of Gd-based contrast agents. Moreover, whereas Gd is not found in biological systems, iron is essential for normal metabolism, and nutritional iron deficiency poses major public health challenges worldwide. Once the carbohydrate shell of ferumoxytol is degraded, the elemental iron at its core is incorporated into the reticuloendothelial system. These considerations position ferumoxytol as a potential game changer in the field of CEMRA and MRI. In this paper, we aim to summarise our experience with the cardiovascular applications of ferumoxytol and provide a brief synopsis of ongoing investigations on ferumoxytol-enhanced MR applications. PMID:27221526

  12. Radiopharmaceuticals in cardiovascular diseases

    International Nuclear Information System (INIS)

    The high incidence of cardiovascular disorders and the attendant morbidity and mortality have encouraged the development of new radiopharmaceuticals for the diagnosis and localisation of coronary diseases. Myocardial perfusion imaging is an invaluable tool for the demonstration of transient ischemia and infarction in heart and identification of viable and non-viable myocardial tissue. Thallium chloride (Tl-201) is the agent currently in wide use but its drawbacks have been well recognised. Hence tremendous amount of research work has been carried out to develop a suitable Tc-99m radiopharmaceutical for this purpose which has resulted in the introduction of two Tc-99m labelled radiopharmaceuticals HEXAMIBI and BATO. These are being tried as myocardial imaging agents these days and the choice amongst these depends on concrete clinical situation. The experimental work involving the synthesis of ligand MIBI, formulation into freeze dried KIT form, quality control procedure, biodistribution studies and finally clinical evaluation of locally produced KIT in human volunteers has now been reported here. Our KIT has been produced for the first time in Pakistan and has been tried on forty five patients in Nuclear Medical Centre, AFIP (Rawalpindi). The results obtained are comparable to those of Ti-201 with a slightly higher liver background in case of MIBI but because of the easy availability MIBI has become agent of choice for myocardial perfusion studies. (author)

  13. Sleep duration, cardiovascular disease, and proinflammatory biomarkers

    Directory of Open Access Journals (Sweden)

    Grandner MA

    2013-07-01

    Full Text Available Michael A Grandner,1,2 Megan R Sands-Lincoln,3 Victoria M Pak,2,4 Sheila N Garland1,5 1Behavioral Sleep Medicine Program, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, PA, USA; 2Center for Sleep and Circadian Neurobiology, University of Pennsylvania, PA, USA; 3Center for Evidence Based Medicine, Elsevier Inc, Philadelphia, PA, USA; 4Division of Sleep Medicine, Perelman School of Medicine, University of Pennsylvania, PA, USA; 5Department of Family Medicine and Community Health, Perelman School of Medicine, University of Pennsylvania, PA, USA Abstract: Habitual sleep duration has been associated with cardiometabolic disease, via several mechanistic pathways, but few have been thoroughly explored. One hypothesis is that short and/or long sleep duration is associated with a proinflammatory state, which could increase risk for cardiovascular and metabolic diseases. This hypothesis has been largely explored in the context of experimental sleep deprivation studies which have attempted to demonstrate changes in proinflammatory markers following acute sleep loss in the laboratory. Despite the controlled environment available in these studies, samples tend to lack generalization to the population at large and acute sleep deprivation may not be a perfect analog for short sleep. To address these limitations, population based studies have explored associations between proinflammatory markers and habitual sleep duration. This review summarizes what is known from experimental and cross-sectional studies about the association between sleep duration, cardiovascular disease, and proinflammatory biomarkers. First, the association between sleep duration with both morbidity and mortality, with a focus on cardiovascular disease, is reviewed. Then, a brief review of the potential role of proinflammatory markers in cardiovascular disease is presented. The majority of this review details specific findings related to specific

  14. Sex differences in cardiovascular function

    Czech Academy of Sciences Publication Activity Database

    Kolář, František; Ošťádal, Bohuslav

    2013-01-01

    Roč. 207, č. 4 (2013), s. 584-587. ISSN 1748-1708 Institutional support: RVO:67985823 Keywords : heart * vascular * risk factors * sex Subject RIV: FA - Cardiovascular Diseases incl. Cardiotharic Surgery Impact factor: 4.251, year: 2013

  15. Cold Weather and Cardiovascular Disease

    Science.gov (United States)

    ... Pressure High Blood Pressure Tools & Resources Stroke More Cold Weather and Cardiovascular Disease Updated:Sep 16,2015 ... Your Heart Health • Watch, Learn & Live Animations Library Cold Weather Fitness Guide Popular Articles 1 Understanding Blood ...

  16. Human and equine cardiovascular endocrinology

    DEFF Research Database (Denmark)

    Vekens, Nicky Van Der; Hunter, Ingrid; Gøtze, Jens Peter;

    2013-01-01

    important species differences, which can partly be explained by variations in physiology or pathophysiology. Most important are physiological differences in heart rate, cardiovascular response to exercise, food and water intake, and molecular elimination in plasma. Pathological differences are even more...

  17. Exercise and the Cardiovascular System

    OpenAIRE

    Saeid Golbidi; Ismail Laher

    2012-01-01

    There are alarming increases in the incidence of obesity, insulin resistance, type II diabetes, and cardiovascular disease. The risk of these diseases is significantly reduced by appropriate lifestyle modifications such as increased physical activity. However, the exact mechanisms by which exercise influences the development and progression of cardiovascular disease are unclear. In this paper we review some important exercise-induced changes in cardiac, vascular, and blood tissues and discuss...

  18. Cardiovascular physiology in space flight

    Science.gov (United States)

    Charles, John B.; Bungo, Michael W.

    1991-01-01

    The effects of space flight on the cardiovascular system have been studied since the first manned flights. In several instances, the results from these investigations have directly contradicted the predictions based on established models. Results suggest associations between space flight's effects on other organ systems and those on the cardiovascular system. Such findings provide new insights into normal human physiology. They must also be considered when planning for the safety and efficiency of space flight crewmembers.

  19. Integrative approaches for cardiovascular disease.

    Science.gov (United States)

    Guarneri, Mimi; Mercado, Nestor; Suhar, Christopher

    2009-12-01

    In the United States, $2.5 trillion is spent on healthcare annually. Seven chronic diseases account for half of all this expense. Of these 7, cardiovascular disease, hypertension, stroke, and diabetes mellitus are largely preventable. Integrative cardiology programs that focus on risk-factor modification through lifestyle change combined with early detection and advanced lipid management offer a new paradigm to the prevention of cardiovascular disease. PMID:19955547

  20. Serotonin receptors as cardiovascular targets

    OpenAIRE

    Villalón, Carlos; De Vries, Peter; Saxena, Pramod Ranjan

    1997-01-01

    textabstractSerotonin exerts complex effects in the cardiovascular system, including hypotension or hypertension, vasodilatation or vasoconstriction, and/or bradycardia or tachycardia; the eventual response depends primarily on the nature of the 5-HT receptors involved. In the light of current 5-HT receptor classification, the authors reanalyse the cardiovascular responses mediated by 5-HT receptors and discuss the established and potential therapeutic applications of 5-HT ligands in the trea...

  1. Cardiovascular effects of basal insulins.

    Science.gov (United States)

    Mannucci, Edoardo; Giannini, Stefano; Dicembrini, Ilaria

    2015-01-01

    Basal insulin is an important component of treatment for both type 1 and type 2 diabetes. One of the principal aims of treatment in patients with diabetes is the prevention of diabetic complications, including cardiovascular disease. There is some evidence, although controversial, that attainment of good glycemic control reduces long-term cardiovascular risk in both type 1 and type 2 diabetes. The aim of this review is to provide an overview of the potential cardiovascular safety of the different available preparations of basal insulin. Current basal insulin (neutral protamine Hagedorn [NPH], or isophane) and basal insulin analogs (glargine, detemir, and the more recent degludec) differ essentially by various measures of pharmacokinetic and pharmacodynamic effects in the bloodstream, presence and persistence of peak action, and within-subject variability in the glucose-lowering response. The currently available data show that basal insulin analogs have a lower risk of hypoglycemia than NPH human insulin, in both type 1 and type 2 diabetes, then excluding additional harmful effects on the cardiovascular system mediated by activation of the adrenergic system. Given that no biological rationale for a possible difference in cardiovascular effect of basal insulins has been proposed so far, available meta-analyses of publicly disclosed randomized controlled trials do not show any signal of increased risk of major cardiovascular events between the different basal insulin analogs. However, the number of available cardiovascular events in these trials is very small, preventing any clear-cut conclusion. The results of an ongoing clinical trial comparing glargine and degludec with regard to cardiovascular safety will provide definitive evidence. PMID:26203281

  2. Estrogen Signaling and Cardiovascular Disease

    OpenAIRE

    Murphy, Elizabeth

    2011-01-01

    Estrogen has pleiotropic effects on the cardiovascular system. The mechanisms by which estrogen confers these pleiotropic effects on cardiovascular function is under active investigation. Until a decade ago, all estrogen signaling was thought to occur by estrogen binding to nuclear estrogen receptors (ERα and ERβ), which bind to DNA and function as ligand activated transcription factors. Estrogen binding to the receptor alters gene expression thereby altering cell function. In 2000 estrogen w...

  3. Molecular Mechanisms of Cardiovascular Aging

    OpenAIRE

    Anna Meiliana; Andi Wijaya

    2013-01-01

    BACKGROUND: The average lifespan of humans is increasing, and with it the percentage of people entering the 65 and older age group is growing rapidly and will continue to do so in the next 20 years. Within this age group, cardiovascular disease will remain the leading cause of death, and the cost associated with treatment will continue to increase. Aging is an inevitable part of life and unfortunately poses the largest risk factor for cardiovascular disease. CONTENT: We provide an overview of...

  4. Microalbuminuria: a Cardiovascular Risk Factor

    OpenAIRE

    ERCAN, Ertuğrul

    2010-01-01

    Albumin is a protein which is charged negatively. By correcting for the daily excretion of creatinine, the albumin creatinin ratio implicates the daily excretion of albumin in spot urine. Albuminuria is a cardiovascular risk factor in patients with diabetes, hypertension, and the general population. Urinary albumin excretion is independently associated with an increased risk of cardiovascular events, even after adjustment for risk factors. Risk has been shown to increase continuously with inc...

  5. YKL-40 - an emerging biomarker in cardiovascular disease and diabetes

    Directory of Open Access Journals (Sweden)

    Rathcke Camilla

    2009-01-01

    Full Text Available Abstract Several inflammatory cytokines are involved in vascular inflammation resulting in endothelial dysfunction which is the earliest event in the atherosclerotic process leading to manifest cardiovascular disease. YKL-40 is an inflammatory glycoprotein involved in endothelial dysfunction by promoting chemotaxis, cell attachment and migration, reorganization and tissue remodelling as a response to endothelial damage. YKL-40 protein expression is seen in macrophages and smooth muscle cells in atherosclerotic plaques with the highest expression seen in macrophages in the early lesion of atherosclerosis. Several studies demonstrate, that elevated serum YKL-levels are independently associated with the presence and extent of coronary artery disease and even higher YKL-40 levels are documented in patients with myocardial infarction. Moreover, elevated serum YKL-40 levels have also been found to be associated with all-cause as well as cardiovascular mortality. Finally, YKL-40 levels are elevated both in patients with type 1 and type 2 diabetes, known to be at high risk for the development of cardiovascular diseases, when compared to non-diabetic persons. A positive association between elevated circulating YKL-40 levels and increasing levels of albuminuria have been described in patients with type 1 diabetes indicating a role of YKL-40 in the progressing vascular damage resulting in microvascular disease. This review describes the present knowledge about YKL-40 and discusses its relation to endothelial dysfunction, atherosclerosis, cardiovascular disease and diabetes and look ahead on future perspectives of YKL-40 research.

  6. Obscenity: Historical and Behavioral Perspectives

    Science.gov (United States)

    Pearce, W. Barnett; Teeter, Dwight L., Jr.

    1975-01-01

    The purpose of this article is to examine the origins of the current state of regulation of sexually explicit materials and to suggest one plausible and practicable solution which should find its way into law. (Author)

  7. Invitation to Consumer Behavior Analysis

    Science.gov (United States)

    Foxall, Gordon R.

    2010-01-01

    This article presents an introduction to consumer behavior analysis by describing the Behavioral Perspective Model of consumer choice and showing how research has, first, confirmed this framework and, second, opened up behavior analysis and behavioral economics to the study of consumer behavior in natural settings. It concludes with a discussion…

  8. Obesity and Cardiovascular Disease.

    Science.gov (United States)

    Ortega, Francisco B; Lavie, Carl J; Blair, Steven N

    2016-05-27

    The prevalence of obesity has increased worldwide over the past few decades. In 2013, the prevalence of obesity exceeded the 50% of the adult population in some countries from Oceania, North Africa, and Middle East. Lower but still alarmingly high prevalence was observed in North America (≈30%) and in Western Europe (≈20%). These figures are of serious concern because of the strong link between obesity and disease. In the present review, we summarize the current evidence on the relationship of obesity with cardiovascular disease (CVD), discussing how both the degree and the duration of obesity affect CVD. Although in the general population, obesity and, especially, severe obesity are consistently and strongly related with higher risk of CVD incidence and mortality, the one-size-fits-all approach should not be used with obesity. There are relevant factors largely affecting the CVD prognosis of obese individuals. In this context, we thoroughly discuss important concepts such as the fat-but-fit paradigm, the metabolically healthy but obese (MHO) phenotype and the obesity paradox in patients with CVD. About the MHO phenotype and its CVD prognosis, available data have provided mixed findings, what could be partially because of the adjustment or not for key confounders such as cardiorespiratory fitness, and to the lack of consensus on the MHO definition. In the present review, we propose a scientifically based harmonized definition of MHO, which will hopefully contribute to more comparable data in the future and a better understanding on the MHO subgroup and its CVD prognosis. PMID:27230640

  9. Autophagy as a Therapeutic Target in Cardiovascular Disease

    Science.gov (United States)

    Nemchenko, Andriy; Chiong, Mario; Turer, Aslan; Lavandero, Sergio; Hill, Joseph A.

    2011-01-01

    The epidemic of heart failure continues apace, and development of novel therapies with clinical efficacy has lagged. Now, important insights into the molecular circuitry of cardiovascular autophagy have raised the prospect that this cellular pathway of protein quality control may be a target of clinical relevance. Whereas basal levels of autophagy are required for cell survival, excessive levels – or perhaps distinct forms of autophagic flux – contribute to disease pathogenesis. Our challenge will be to distinguish mechanisms that drive adaptive versus maladaptive autophagy and to manipulate those pathways for therapeutic gain. Recent evidence suggests this may be possible. Here, we review the fundamental biology of autophagy and its role in a variety of forms of cardiovascular disease. We discuss ways in which this evolutionarily conserved catabolic mechanism can be manipulated, discuss studies presently underway in heart disease, and provide our perspective on where this exciting field may lead in the future. PMID:21723289

  10. Future Research Directions for Multimorbidity Involving Cardiovascular Diseases.

    Science.gov (United States)

    Salive, Marcel E

    2016-05-01

    Multimorbidity, defined as the co-occurrence of two or more chronic conditions, increases with age and may be found in approximately two-thirds of older adults in population studies, commonly including a variety of cardiovascular risk factors and chronic diseases. This article offers a research agenda for cardiovascular disease from a patient-centered multimorbidity perspective. Definitional issues remain for multimorbidity, along with high interest in understanding the inter-relationships between aging, diseases, treatments, and organ dysfunction in the development and progression of multimorbidity. Clinical trials, practice-based and population-based observational studies, and linkages of big data can play a role in improving health outcomes among persons with multimorbidity. PMID:27113155

  11. Cardiovascular Risk Factors and Cardiovascular Hyperreactivity in Young Venezuelans

    Directory of Open Access Journals (Sweden)

    Sady Montes Amador

    2015-07-01

    Full Text Available Background: cardiovascular hyperreactivity in young people has been associated with different risk factors and a family history of hypertension. Objective: to determine the association between a family history of hypertension and cardiovascular risk factors with cardiovascular hyperreactivity. Method: a correlational, cross-sectional study was conducted in a universe of 77 young individuals aged 18 to 40 years from the Churuguara parish of the Falcon State in Venezuela. The variables were: age, sex, skin color, family history of hypertension, medical history of hypertension, diabetes mellitus, alcohol consumption, salt intake, physical activity and body mass index. The diastolic and systolic blood pressure before and after the pressor response elicited by an isometric exercise were determined as hemodynamic variables. Results: thirteen percent of the participants developed vascular reactivity after the hand-held weight test. Cardiovascular hyperreactivity is three times higher in individuals with a family history of hypertension. Sixty percent of those with a body mass index greater than or equal to 27 kg/m2 are hyperreactive. There is a higher cardiovascular response to the hand-held weight test as the consumption of alcohol increases. Thirty three point three percent of the participants who smoke are hyperreactive. Conclusions: there is a significant association between a family history of hypertension, obesity, salt intake, alcohol consumption and vascular hyperreactivity.

  12. Networks: An Economic Perspective

    CERN Document Server

    Jackson, Matthew O; Zenou, Yves

    2016-01-01

    We discuss social network analysis from the perspective of economics. We organize the presentaion around the theme of externalities: the effects that one's behavior has on others' well-being. Externalities underlie the interdependencies that make networks interesting. We discuss network formation, as well as interactions between peoples' behaviors within a given network, and the implications in a variety of settings. Finally, we highlight some empirical challenges inherent in the statistical analysis of network-based data.

  13. Experiences and perceptions about cause and prevention of cardiovascular disease among people with cardiometabolic conditions: findings of in-depth interviews from a peri-urban Nepalese community

    Directory of Open Access Journals (Sweden)

    Natalia Oli

    2014-04-01

    Full Text Available Background: Nepal currently faces an increasing burden of cardiovascular disease (CVD. Earlier studies on health literacy and the behavior dimension of cardiovascular health reported a substantial gap between knowledge and practice. Objective: This qualitative study aimed to deepen understanding of the community perspective on cardiovascular health from the patients’ viewpoint. Design: We conducted in-depth interviews (IDIs with 13 individuals with confirmed heart disease, hypertension, or diabetes mellitus. All participants provided verbal consent. We used an IDI guide to ask respondents about their perception and experiences with CVD, particularly regarding causation and preventability. We manually applied qualitative content analysis to evaluate the data and grouped similar content into categories and subcategories. Results: Respondents perceived dietary factors, particularly consumption of salty, fatty, and oily food, as the main determinants of CVD. Similarly, our respondents unanimously linked smoking, alcohol intake, and high blood pressure with cardiac ailments but reported mixed opinion regarding the causal role of body weight and physical inactivity. Although depressed and stressed at the time of diagnosis, respondents learned to handle their situation better over time. Despite good family support for health care, the financial burden of disease was a major issue. All respondents understood the importance of lifestyle modification and relied upon health professionals for information and motivation. Respondents remarked that community awareness of CVD was inadequate and that medical doctors or trained local people should help increase awareness. Conclusions: This study provided insight into the perceptions of patients regarding CVD. Respondents embraced the importance of lifestyle modification only after receiving their diagnosis. Although better health care is important in terms of aiding patients to better understand and cope with

  14. Experiences and perceptions about cause and prevention of cardiovascular disease among people with cardiometabolic conditions: findings of in-depth interviews from a peri-urban Nepalese community

    Science.gov (United States)

    Oli, Natalia; Vaidya, Abhinav; Subedi, Madhusudan; Krettek, Alexandra

    2014-01-01

    Background Nepal currently faces an increasing burden of cardiovascular disease (CVD). Earlier studies on health literacy and the behavior dimension of cardiovascular health reported a substantial gap between knowledge and practice. Objective This qualitative study aimed to deepen understanding of the community perspective on cardiovascular health from the patients’ viewpoint. Design We conducted in-depth interviews (IDIs) with 13 individuals with confirmed heart disease, hypertension, or diabetes mellitus. All participants provided verbal consent. We used an IDI guide to ask respondents about their perception and experiences with CVD, particularly regarding causation and preventability. We manually applied qualitative content analysis to evaluate the data and grouped similar content into categories and subcategories. Results Respondents perceived dietary factors, particularly consumption of salty, fatty, and oily food, as the main determinants of CVD. Similarly, our respondents unanimously linked smoking, alcohol intake, and high blood pressure with cardiac ailments but reported mixed opinion regarding the causal role of body weight and physical inactivity. Although depressed and stressed at the time of diagnosis, respondents learned to handle their situation better over time. Despite good family support for health care, the financial burden of disease was a major issue. All respondents understood the importance of lifestyle modification and relied upon health professionals for information and motivation. Respondents remarked that community awareness of CVD was inadequate and that medical doctors or trained local people should help increase awareness. Conclusions This study provided insight into the perceptions of patients regarding CVD. Respondents embraced the importance of lifestyle modification only after receiving their diagnosis. Although better health care is important in terms of aiding patients to better understand and cope with their disease

  15. Psychosocial Stress and Cardiovascular Disease Part 2: Effectiveness of the Transcendental Meditation Program in Treatment and Prevention

    OpenAIRE

    Walton, Kenneth G.; Schneider, Robert H.; Nidich, Sanford I.; Salerno, John W.; Nordstrom, Cheryl K; Merz, C. Noel Bairey

    2002-01-01

    Psychosocial stress is a nontraditional risk factor for cardiovascular morbidity and mortality that may respond to behavioral or psychosocial interventions. To date, studies applying such interventions have reported a wide range of success rates in treatment or prevention of cardiovascular disease (CVD). The authors focus on a natural medicine approach that research indicates reduces both psychosocial and traditional risk factors for cardiovascular disease—the Transcendental Meditation (TM) p...

  16. The rat - Cardiovascular pharmacology

    Directory of Open Access Journals (Sweden)

    Sotomayor-Herazo Aristides

    2012-06-01

    locura inducida porlas sustancias, donde la culpa proyectada y la negación campean a la par dela visión del mundo degradado y alucinante como construcción alterna de larealidad del drogadicto.A falta de una vida plena llena de realizaciones, el vacío interno, los sentimientosde soledad, la futilidad mediatizada, la ausencia de un verdadero sentido de lavida, el existir solo por el principio del placer, constituyen modos de vida sinsignificado, donde comanda el cerebro del reptil que llevamos dentro, no digoque el de mamífero porque sería ofender a tan nobles animales.En el desarrollo de esta obra, y en la realidad, vemos como se encuentratrastocado, cuando no ausente, el sentido de lo espiritual. La incapacidad paraexperimentar el dolor del prójimo, posiblemente se deba a una falla del hazde neuronas conocidas como “neuronas espejo” descubiertas por el equipoinvestigador de la Universidad de Parma, liderado por Giacomo Rizzolatti en1996. El sistema de “neuronas espejo” permite hacer propias las acciones, sensaciones y emociones de los demás; sirve paraexplicar las bases neurobiológicas de la empatíay, su ausencia o daño, ayudaría a comprender lasbases del trastorno antisocial de la personalidado psicopatía. Grave patología caracterizadapor la imposibilidad del sujeto para vivenciarlos sentimientos de sus iguales, por lo mismo,son incapaces para sentir culpa o ansiedad, losque los lleva a una ausencia de moralidad y decapacidad para experimentar compasión por elotro, eso los convierte en depredadores de los herdemás.La droga prospera en estos individuosy daña las conexiones lógicas de sus funciones,socio-patizándolos aún más; así nos impresionaArístides, con unos personajes desalmados,afectados por este destructor flagelo. Esta esla saga en la que nos introduce con magistralhabilidad el autor.CHISTIAN AYOLA GÓMEZMédico Especialista en PsiquiatriaFARMACOLOGIA CARDIOVASCULAR:El conocimiento de la farmacología, ciencia vitalen la formaci

  17. Freqüência cardíaca e risco cardiovascular Heart rate and cardiovascular risk

    Directory of Open Access Journals (Sweden)

    Luiz Antonio Machado César

    2007-10-01

    Full Text Available A freqüência cardíaca (FC também está no centro das determinantes do tempo de vida dos seres vivos animais. Há quase uma constante quando se multiplica a FC pelo número de anos que, em média, vive um animal. O ser humano também tem correlações interessantes de tempo de vida e FC, com estudos epidemiológicos demonstrando maior sobrevivência naqueles com menor FC em repouso, hipertensos, com doença coronariana e na população geral. Neste artigo, revemos estes estudos epidemiológicos e a perspectiva de se, de fato reduzindo a FC, poderemos aumentar o tempo de vida, no caso dos pacientes com doença cardiovascular, de forma independente de outros fatores.Heart rate (HR is known to be one of the factors that in the animal world are related to mortality. When one multiplies resting HR by the average life time, for each animal species, the result is almost the same number, similar to a constant. Apparently, each class of living beings has its "maximal number of heart beats for a life". Herein considerations are made about the relationship between HR and survival in human beings. Some epidemiological studies are reviewed, especially those related to cardiovascular and coronary diseases correlated to deaths and discussions are directed towards the perspective of living longer by lowering the HR.

  18. SISTEMA ENDOCANABINOIDE: MODIFICANDO LOS FACTORES DE RIESGO CARDIOVASCULAR Endocannabinoid system: modifying cardiovascular risk factors

    Directory of Open Access Journals (Sweden)

    John Edwin Feliciano Alfonso

    2006-10-01

    Full Text Available La necesidad de alcanzar un tratamiento óptimo para el tabaquismo, la obesidad y sus comorbilidades, conocidos factores de riesgo cardiovascular, ha fomentado la búsqueda de objetivos terapéuticos novedosos. Es el caso del sistema endocanabinoide, involucrado en diversos fenómenos fisiológicos entre los que se encuentran el refuerzo de ciertos comportamientos y la regulación del apetito. La sobreactivación de este sistema altera la homeostasis corporal predisponiendo a dependencias o a un aumento en la ingesta alimentaria, lo que puede traducirse en tabaquismo u obesidad. La intervención farmacológica sobre el sistema endocanabinoide puede contribuir al manejo de estos factores de riesgo cardiovascular, teniendo en cuenta que a tales beneficios se suman otros independientes de la suspensión del tabaquismo o la reducción de peso, como el aumento del colesterol de alta densidad, la disminución de triglicéridos y la mejoría del control glucémico en pacientes con diabetes. Ensayos clínicos controlados aleatorizados adelantados en poblaciones con diferentes características, han evaluado la utilidad de la regulación farmacológica del sistema endocanabinoide; confirmando su eficacia en personas con factores de riesgo cardiovascular establecidos.The need for an optimal treatment for smoking, obesity and their comorbidities, well-known cardiovascular risk factors; has prompted the search for novel therapeutic targets. This is the case of the endocannabinoid system, involved in several physiological phenomena including the reinforcement of certain behaviors and the regulation of appetite.

  19. Vitamin D and Cardiovascular Disease

    Directory of Open Access Journals (Sweden)

    Martin R. Grübler

    2013-07-01

    Full Text Available Vitamin D deficiency, as well as cardiovascular diseases (CVD and related risk factors are highly prevalent worldwide and frequently co-occur. Vitamin D has long been known to be an essential part of bone metabolism, although recent evidence suggests that vitamin D plays a key role in the pathophysiology of other diseases, including CVD, as well. In this review, we aim to summarize the most recent data on the involvement of vitamin D deficiency in the development of major cardiovascular risk factors: hypertension, obesity and dyslipidemia, type 2 diabetes, chronic kidney disease and endothelial dysfunction. In addition, we outline the most recent observational, as well as interventional data on the influence of vitamin D on CVD. Since it is still an unresolved issue whether vitamin D deficiency is causally involved in the pathogenesis of CVD, data from randomized controlled trials (RCTs designed to assess the impact of vitamin D supplementation on cardiovascular outcomes are awaited with anticipation. At present, we can only conclude that vitamin D deficiency is an independent cardiovascular risk factor, but whether vitamin D supplementation can significantly improve cardiovascular outcomes is still largely unknown.

  20. Gap junctions in the cardiovascular and immune systems

    Directory of Open Access Journals (Sweden)

    R. Rozental

    2000-04-01

    Full Text Available Gap junctions are clusters of intercellular channels directly connecting the cytoplasm of adjacent cells. These channels are formed by proteins named connexins and are present in all metazoan organisms where they serve diverse functions ranging from control of cell growth and differentiation to electric conduction in excitable tissues. In this overview we describe the presence of connexins in the cardiovascular and lympho-hematopoietic systems giving the reader a summary of the topics to be covered throughout this edition and a historical perspective of the discovery of gap junctions in the immune system.

  1. Cardiovascular Disease and Thyroid Function

    DEFF Research Database (Denmark)

    Faber, Jens; Selmer, Christian

    2014-01-01

    Thyroid function has a profound effect on the heart, and both all-cause and cardiovascular mortality rates are increased in hyperthyroidism. New-onset atrial fibrillation carries a prolonged risk for the development of hyperthyroidism, suggesting altered availability of thyroid hormones at the ce......Thyroid function has a profound effect on the heart, and both all-cause and cardiovascular mortality rates are increased in hyperthyroidism. New-onset atrial fibrillation carries a prolonged risk for the development of hyperthyroidism, suggesting altered availability of thyroid hormones...... at the cellular level. Subclinical hyperthyroidism is associated with increased left ventricular mass of the heart, which reverts after obtaining euthyroidism. Mortality and risk of major cardiovascular events are increased. Subclinical hypothyroidism is also associated with subtle changes in the heart, e.g. its...

  2. Cardiovascular autonomic neuropathy in diabetes

    DEFF Research Database (Denmark)

    Spallone, Vincenza; Ziegler, Dan; Freeman, Roy;

    2011-01-01

    Cardiovascular Autonomic Neuropathy (CAN) Subcommittee of Toronto Consensus Panel on Diabetic Neuropathy worked to update CAN guidelines, with regard to epidemiology, clinical impact, diagnosis, usefulness of CAN testing, and management. CAN is the impairment of cardiovascular autonomic control...... in the setting of diabetes after exclusion of other causes. The prevalence of confirmed CAN is around 20%, and increases up to 65% with age and diabetes duration. Established risk factors for CAN are glycaemic control in type 1 and a combination of hypertension, dyslipidemia, obesity and glycaemic control...... in type 2 diabetes. CAN is a risk marker of mortality and cardiovascular morbidity, and possibly a progression promoter of diabetic nephropathy. Criteria for CAN diagnosis and staging are: 1. one abnormal cardio-vagal test identifies possible or early CAN; 2. at least two abnormal cardio-vagal tests...

  3. Cognitive dysfunction after cardiovascular surgery

    DEFF Research Database (Denmark)

    Funder, K S; Steinmetz, J; Rasmussen, L S

    2009-01-01

    This review describes the incidence, risk factors, and long-term consequences of cognitive dysfunction after cardiovascular surgery. Postoperative cognitive dysfunction (POCD) is increasingly being recognized as an important complication, especially in the elderly. A highly sensitive neuropsychol......This review describes the incidence, risk factors, and long-term consequences of cognitive dysfunction after cardiovascular surgery. Postoperative cognitive dysfunction (POCD) is increasingly being recognized as an important complication, especially in the elderly. A highly sensitive...... neuropsychological test battery must be used to detect POCD and a well-matched control group is very useful for the analysis and interpretation of the test RESULTS: Cardiovascular surgery is associated with a high incidence of POCD. Cardiopulmonary bypass was thought to explain this difference, but randomized...

  4. Lymphatic System in Cardiovascular Medicine.

    Science.gov (United States)

    Aspelund, Aleksanteri; Robciuc, Marius R; Karaman, Sinem; Makinen, Taija; Alitalo, Kari

    2016-02-01

    The mammalian circulatory system comprises both the cardiovascular system and the lymphatic system. In contrast to the blood vascular circulation, the lymphatic system forms a unidirectional transit pathway from the extracellular space to the venous system. It actively regulates tissue fluid homeostasis, absorption of gastrointestinal lipids, and trafficking of antigen-presenting cells and lymphocytes to lymphoid organs and on to the systemic circulation. The cardinal manifestation of lymphatic malfunction is lymphedema. Recent research has implicated the lymphatic system in the pathogenesis of cardiovascular diseases including obesity and metabolic disease, dyslipidemia, inflammation, atherosclerosis, hypertension, and myocardial infarction. Here, we review the most recent advances in the field of lymphatic vascular biology, with a focus on cardiovascular disease. PMID:26846644

  5. Cardiovascular Session Summary

    Science.gov (United States)

    Raven, Peter; Schneider, Sue

    1999-01-01

    It was apparent that the bed-rest and spaceflight data indicated that decreases in plasma volume and cardiac atrophy along with cardiac remodeling were fundamental changes which predisposed many astronauts to post flight orthostatic intolerance. Despite the recently acquired in-flight and post-flight muscle sympathetic nerve activity findings suggesting that the sympathetic nerve responses were appropriate there remains significant contrary data from bed-rest studies, post- flight stand tests and hind-limb unweighted rat studies that suggest that the vasoconstrictive responses were compromised at least insufficient in susceptible individuals. The key issues raised is whether a diminished increase in sympathetic activity from baseline without changes in 254 First Biennial Space Biomedical Investigators'Workshop Cardiovascular peak response or receptor adaptations is an abnormal response or is an individual variance of response to the accentuated decrease in stroke volume. Data relating autonomic neural control of heart rate were presented to suggest that the vagal and sympathetic control of heart rate was attenuated. Also, bed-rest and space flight induced attenuated baroreflex control of heart rate was shown to be restored to pre-bedrest function by one bout of maximal dynamic exercise. However, these data were confounded by relying on the use of R-R interval as a measure of efferent responses of the baroreflex during a condition in which the baseline heart rate was changed. Clearly the idea that the autonomic control of heart rate may be changed by microgravity needs further investigation. This direction is suggested despite the fact that in the triple product (HR x SV x TPR = MAP) assessment of the regulation of arterial blood pressure during orthostasis the role of the HR reflex may be less influential than that associated. with cardiac atrophy (SV changes) and aberrant sympathetic vasoconstriction (resistance) changes. Although sympathetic nerve activity

  6. Characteristics of Smokers from a National Sample Who Engaged in Any Physical Activity: Implications for Cardiovascular Health Intervention

    Science.gov (United States)

    Patterson, Freda; Lenhart, Clare M.

    2016-01-01

    Background: Tobacco is a major cause of cardiovascular disease, and current treatments lack long-term efficacy. Promoting physical activity may be a viable population-level approach to improving cardiovascular health among smokers. Purpose: To characterize smokers engaging in any physical activity based on demographics, quitting behaviors, health…

  7. Cardiovascular disease incidence and survival

    DEFF Research Database (Denmark)

    Byberg, Stine; Agyemang, Charles; Zwisler, Ann Dorthe;

    2016-01-01

    Studies on cardiovascular disease (CVD) incidence and survival show varying results between different ethnic groups. Our aim was to add a new dimension by exploring the role of migrant status in combination with ethnic background on incidence of-and survival from-CVD and more specifically acute...... of some types of cardiovascular disease compared to Danish-born. Family-reunified migrants on the other hand had lower rates of CVD. All migrants had better survival than Danish-born indicating that migrants may not always be disadvantaged in health....

  8. Enfermedad cardiovascular en Costa Rica

    OpenAIRE

    Lizzie M. Castillo S; Ana Teresa Alvarado G; María Isabel Sánchez V

    2006-01-01

    En Costa Rica la enfermedad cardiovascular cobra en promedio 6 vidas por día, lo cual representa un aumento escalonado en los últimos años, debido en su mayoría a cambios en el estilo de vida del costarricense. Además, llama la atención, que factores de riesgo para enfermedad cardiovascular como son el fumado, obesidad infantil, alcoholismo, diabetes, dislipidemia e hipertensión han mostrado un incremento en su incidencia. Por lo tanto,se pretende realizar una revisión de los programas de det...

  9. Exploring Perspectives of Individuals with Intellectual Disabilities and Histories of Challenging Behaviors about Family Relationships: An Emergent Topic in a Grounded Theory Focus Group Study

    Science.gov (United States)

    Brown, Julie F.; Hamilton-Mason, Johnnie; Maramaldi, Peter; Barnhill, L. Jarrett

    2016-01-01

    The perspectives of individuals with intellectual disabilities (ID) about family relationships are underrepresented in the literature. The topic of family relationships emerged in a grounded theory exploratory focus group study that involved thirty dually diagnosed participants with moderate or mild intellectual disabilities and histories of…

  10. Cardiovascular Costs of Emotion Suppression Cross Ethnic Lines1

    OpenAIRE

    Nicole A Roberts; Levenson, Robert W.; Gross, James J.

    2008-01-01

    Previous research has shown that inhibiting emotion-expressive behavior (emotion suppression) leads to increased sympathetic activation of the cardiovascular system (Gross & Levenson, 1993). Ethnic differences have been reported in how frequently suppression is used as an emotion regulation strategy (Gross & John, 2003); however, it remains unknown whether there are ethnic differences in the physiological consequences of suppression. To test this, 168 participants from four ethnic groups (Afr...

  11. The Role of Healthy Lifestyle in the Primordial Prevention of Cardiovascular Disease.

    Science.gov (United States)

    Claas, Steven A; Arnett, Donna K

    2016-06-01

    Whereas primary prevention seeks to forestall development of disease in individuals with elevated risk, primordial prevention seeks to preempt the development of risk factors. Health behaviors-characterized as "lifestyle" factors-are key interventional targets in primordial prevention of cardiovascular disease. Appropriate dietary intake, including limiting salt and saturated fat consumption, can reduce the risk of developing hypertension and dyslipidemias. Regular physical activity is associated with lower blood pressure and healthier lipid profiles. Diet and exercise are critical to maintaining weight conducive to cardiovascular health. Behavioral factors such as stress management, sleep duration, portion control, and meal timing may play a role in weight management and offer additional routes of intervention. Any smoking elevates cardiovascular risk. Although lifestyle modification programs can be instrumental in reaching public health goals, maintaining cardiovascular health should not be a matter solely of willpower. Ideally, structural and social forces should make healthy lifestyles the default option. PMID:27142061

  12. Society for Cardiovascular Angiography and Interventions

    Science.gov (United States)

    ... jointly produced, collaborated with, or endorsed by the Society of Cardiovascular Angiography and Interventions. Press & News » Review ... SCAI Member? Create an Account Advertisement Advertisement The Society for Cardiovascular Angiography and Interventions Foundation, 1100 17th ...

  13. Comparative cardiovascular safety of dementia medications

    DEFF Research Database (Denmark)

    Fosbøl, Emil L; Peterson, Eric D; Holm, Ellen;

    2012-01-01

    To compare the cardiovascular safety of currently marketed dementia medications in new users in the United States and Denmark.......To compare the cardiovascular safety of currently marketed dementia medications in new users in the United States and Denmark....

  14. College problem students' anomic behaviors from the perspective of Social Role Theory%社会角色理论视域下高校问题学生行为失范

    Institute of Scientific and Technical Information of China (English)

    李飞

    2012-01-01

    College problem students' anomic behaviors have attracted the universal social attention. Based on previous studies, this thesis introduces the Social Role Theory into the research of this problem from a practical and brand new perspective which redefines "problem students" and "anomic behavior". What's more, this paper incisively analyzes the causes for college problem students' anomic behavior from the following four aspects: role shift, role conflict, role mismatch, and role failure. And it also puts forward the corresponding countermeasures, which develops a new way of thinking for education administrator trying to find solutions to students' anomic behavior.%高校“问题学生”行为失范已得到社会的普遍关注,基于前人研究的基础,立足客观实际,开辟新视角,将社会角色理论引入对这一问题的研究,不仅对“问题学生”和“行为失范”进行了重新界定,从角色转换、角色冲突、角色错位、角色失败四个方面分析了高校“问题学生”行为失范产生的缘由,并提出了相应的对策。

  15. Cardiovascular risk factors in men

    DEFF Research Database (Denmark)

    Gyllenborg, J; Rasmussen, S L; Borch-Johnsen, Knut;

    2001-01-01

    Males have higher risk of cardiovascular disease (CVD) than premenopausal females. Gonadal steroids are probably involved in the gender difference in CVD, but previous results have been conflicting. We investigated the associations between CVD risk factors and sex hormones in a cross...

  16. Women's cardiovascular health in Africa.

    Science.gov (United States)

    Mocumbi, Ana Olga; Sliwa, Karen

    2012-03-01

    The predominant pattern of cardiovascular diseases in sub-Saharan Africa is that of poverty-related conditions (rheumatic heart valve disease, untreated congenital heart disease, tuberculous pericarditis) and diseases of unclear aetiology with a higher prevalence in this part of the world (peripartum cardiomyopathy, endomyocardial fibrosis). However, the prevalence of the traditional risk factors for cardiovascular diseases such as hypertension and marked obesity is high in a number of sub-Saharan settings, although they vary considerably among countries, urban/rural locations and specific subpopulations. In urban settings, hypertensive heart disease with systolic and diastolic function contributes substantially to morbidity. Awareness of the general public and health workers about the burden of cardiovascular diseases in women must be increased, and risk factor control programmes must be included in the health research agenda on the African continent. Improvement in health services with coordination of maternal health services and non-communicable diseases is also needed. This review focuses on the current knowledge of cardiovascular healthcare of women in sub-Saharan Africa, particularly their propensity for various forms of heart disease, access to healthcare, treatment received within the respective healthcare system, response to therapy and mortality. It highlights the gaps in knowledge and the paucity of data in most of these aspects. PMID:22350029

  17. Hedgehog morphogen in cardiovascular disease

    NARCIS (Netherlands)

    Bijlsma, Maarten F.; Peppelenbosch, Maikel P.; Spek, C. Arnold

    2006-01-01

    In this review, we focus on the basic biology of the important developmental Hedgehog ( Hh) protein family, its general function in development, pathway mechanisms, and gene discovery and nomenclature. Hh function in cardiovascular development and recent findings concerning Hh signaling in ischemia

  18. Cardiovascular calcification. An inflammatory disease

    International Nuclear Information System (INIS)

    Cardiovascular calcification is an independent risk factor for cardiovascular morbidity and mortality. This disease of dysregulated metabolism is no longer viewed as a passive degenerative disease, but instead as an active process triggered by pro-inflammatory cues. Furthermore, a positive feedback loop of calcification and inflammation is hypothesized to drive disease progression in arterial calcification. Both calcific aortic valve disease and atherosclerotic arterial calcification may possess similar underlying mechanisms. Early histopathological studies first highlighted the contribution of inflammation to cardiovascular calcification by demonstrating the accumulation of macrophages and T lymphocytes in 'early' lesions within the aortic valves and arteries. A series of in vitro work followed, which gave a mechanistic insight into the stimulation of smooth muscle cells to undergo osteogenic differentiation and mineralization. The emergence of novel technology, in the form of animal models and more recently molecular imaging, has enabled accelerated progression of this field, by providing strong evidence regarding the concept of this disorder as an inflammatory disease. Although there are still gaps in our knowledge of the mechanisms behind this disorder, this review discusses the various studies that have helped form the concept of the inflammation-dependent cardiovascular calcification paradigm. (author)

  19. Seasonality of cardiovascular risk factors

    DEFF Research Database (Denmark)

    Marti-Soler, Helena; Gubelmann, Cédric; Aeschbacher, Stefanie;

    2014-01-01

    OBJECTIVE: To assess the seasonality of cardiovascular risk factors (CVRF) in a large set of population-based studies. METHODS: Cross-sectional data from 24 population-based studies from 15 countries, with a total sample size of 237 979 subjects. CVRFs included Body Mass Index (BMI) and waist...

  20. Serotonin receptors as cardiovascular targets

    NARCIS (Netherlands)

    C.M. Villalón (Carlos); P.A.M. de Vries (Peter); P.R. Saxena (Pramod Ranjan)

    1997-01-01

    textabstractSerotonin exerts complex effects in the cardiovascular system, including hypotension or hypertension, vasodilatation or vasoconstriction, and/or bradycardia or tachycardia; the eventual response depends primarily on the nature of the 5-HT receptors involved. In the light of current 5-HT

  1. Epac and the cardiovascular system

    NARCIS (Netherlands)

    Schmidt, Martina; Sand, Carsten; Jakobs, Karl H.; Michel, Martin C.; Weernink, Paschal A. Oude

    2007-01-01

    Exchange protein activated by cyclic AMP (Epac) - a cyclic AMP-activated guanine nucleotide exchange factor for Ras-like GTPases - has emerged as a novel mediator of pivotal processes in the cardiovascular system, including cellular calcium handling, hypertrophy, integrin-mediated cell adhesion, est

  2. [Psoriasis and cardiovascular risk factors].

    Science.gov (United States)

    Tal, Roy; Pavlovsky, Lev; David, Michael

    2012-10-01

    Psoriasis is a common inflammatory skin disease which may dramatically affect patients' lives. This chronic disease is characterized by a protracted course of alternating remissions and relapses. In recent years, the attention of researchers has focused on the association between psoriasis and cardiovascular disease risk factors. This review summarizes the literature on this topic with an emphasis on research conducted in Israel. PMID:23316664

  3. The psychobiology of strained breathing and its cardiovascular implications : A functional system review

    NARCIS (Netherlands)

    Fokkema, DS

    1999-01-01

    Strained breathing is a natural respiratory pattern, with cardiovascular implications. It is associated with social factors, attention, expectation, and anxiety and with defense behavior in animals. An inhibition of active behavior is characteristic. Strained breathing is based on the functional het

  4. Social anxiety and cardiovascular responses to active coping conditions

    Directory of Open Access Journals (Sweden)

    MARGIT GRAMER

    2006-03-01

    Full Text Available This study assessed the influence of trait social anxiety on cardiovascular, emotional and behavioral responses to active performance situations representing social and cognitive demands. Thirty-six male and thirty-six female students categorized as either high or low in trait social anxiety performed a mental arithmetic task and two interpersonal tasks requiring persuasive behavior: Preparation and Performance of a Speech, Role-played Interpersonal Interactions. The cardiovascular effects of social anxiety varied over experimental stressors and appear to reflect differences in effort or task engagement rather than differential affective experiences. During Role-played Interactions high socially anxious subjects displayed lower increases in systolic blood pressure compared to low anxious participants. This effect was partially mediated by behavioral indicators of social competence and suggests a more inhibited coping approach of socially anxious participants. Findings for Mental Arithmetic were in the opposite direction, high socially anxious subjects displayed greater heart rate effects. In the absence of group differences in state anxiety this effect might result from stronger audience effects on effort or task motivation in socially anxious participants. These findings strengthen the view that active performance situations elicit cardiovascular effects that are largely attributable to differences in task engagement. The data also indicate the importance of considering situational factors in social anxiety research.

  5. Cardiovascular magnetic resonance of the right ventricle

    OpenAIRE

    Alpendurada, Francisco Diogo

    2013-01-01

    Introduction: Whilst most of the attention has been devoted to the left ventricle in cardiovascular disease, the right ventricle has been somewhat neglected. In the last decades, there has been a renewal of interest in the right ventricle, in part driven by advances in cardiovascular imaging. Methods: Cardiovascular magnetic resonance is arguably the best imaging modality for the study of the right ventricle. In this research thesis, cardiovascular magnetic resonance w...

  6. Sex steroids and cardiovascular disease

    Directory of Open Access Journals (Sweden)

    Bu Beng Yeap

    2014-04-01

    Full Text Available As men grow older, testosterone (T levels decline and the significance of this change is debated. The evidence supporting a causal role for lower circulating T, or its metabolites dihydrotestosterone (DHT and estradiol, in the genesis of atherosclerosis and cardiovascular disease (CVD in men is limited. Observational studies associate low baseline T levels with carotid atherosclerosis, aortic and peripheral vascular disease, and with the incidence of cardiovascular events and mortality. Studies using mass spectrometry suggest that when total T is assayed optimally, calculation of free T might not necessarily improve risk stratification. There is limited evidence to support an association of estradiol with CVD. Interventional studies of T therapy in men with coronary artery disease have shown beneficial effects on exercise-induced myocardial ischemia. However, placebo-controlled, randomized clinical trials (RCTs of T therapy in men with the prespecified outcomes of cardiovascular events or deaths are lacking. Meta-analyses of randomized controlled trials of T published up to 2010 found no increase in cardiovascular events, mortality, or prostate cancer with therapy. Recently, in a trial of older men with mobility limitations, men randomized to receive a substantial dose of T reported cardiovascular adverse effects. This phenomenon was not reported from a comparable trial where men received a more conservative dose of T, suggesting a prudent approach should be adopted when considering therapy in frail older men with existing CVD. Adequately powered RCTs of T in middle-aged and older men are needed to clarify whether or not hormonal intervention would reduce the incidence of CVD.

  7. Cardiovascular adverse effects of phenytoin.

    Science.gov (United States)

    Guldiken, B; Rémi, J; Noachtar, Soheyl

    2016-05-01

    Phenytoin is an established drug in the treatment of acute repetitive seizures and status epilepticus. One of its main advantages over benzodiazepines is the less sedative effect. However, the possibility of cardiovascular adverse effects with the intravenous use of phenytoin cause a reluctance to its usage, and this has lead to a search for safer anticonvulsant drugs. In this study, we aimed to review the studies which evaluated the safety of phenytoin with respect to cardiovascular adverse effects. The original clinical trials and case reports listed in PUBMED in English language between the years of 1946-2014 were evaluated. As the key words, "phenytoin, diphenylhydantoin, epilepsy, seizure, cardiac toxicity, asystole, arrhythmia, respiratory arrest, hypotension, death" were used. Thirty-two clinical trials and ten case reports were identified. In the case reports, a rapid infusion rate (>50 mg/min) of phenytoin appeared as the major cause of increased mortality. In contrast, no serious cardiovascular adverse effects leading to death were met in the clinical trials which applied the recommended infusion rate and dosages. An infusion rate of 50 mg/min was reported to be safe for young patients. For old patients and patients with a cardiovascular co-morbidity, a slower infusion rate was recommended with a careful follow-up of heart rhythm and blood pressure. No cardiovascular adverse effect was reported in oral phenytoin overdoses except one case with a very high serum phenytoin level and hypoalbuminemia. Phenytoin is an effective and well tolerated drug in the treatment of epilepsy. Intravenous phenytoin is safe when given at recommended infusion rates and doses. PMID:26645393

  8. Modelos experimentales de enfermedad cardiovascular Experimental models of cardiovascular disease

    Directory of Open Access Journals (Sweden)

    A. Gil Hernández

    2007-04-01

    Full Text Available El presente trabajo describe los modelos experimentales de utilidad clínica en el estudio de las enfermedades cardiovasculares y hace énfasis en los modelos usados para determinar los mecanismos fisiopatológicos de la aterosclerosis, así como para evaluar los efectos de productos nutricionales y farmacológicos sobre el desarrollo de este proceso inflamatorio complejo común a muchas enfermedades cardiovasculares. Se revisan los modelos animales en los que se puede inducir aterosclerosis por cambios en la composición de la dieta y los modelos animales en los que la alteración de uno o más genes (animales knock-out y knock-in, o la incorporación de genes foráneos de otras especies, da lugar a la aparición de hiperlipidemia con riesgo asociado de aparición de enfermedad cardiovascular temprana. Por otra parte, se consideran algunas de las líneas celulares más utilizadas en el estudio de los mecanismos moleculares de la aterogénesis y de evaluación de sustancias con interés nutricional o farmacológico.The present work describes clinically useful experimental models for the study of cardiovascular disease and emphasites the models used to determine the pathophysiologic mechanisms of atherosclerosis, as well as to evaluate the effects of nutritional and pharmacological products on the development of this complex inflammatory process present in many cardiovascular diseases. Animal models in which ahterosclerosis may be induced by dietary changes are reviewed, as well as those in which modification in one or more genes (knock-out and knock-in animals, or the incorporation of foreign genes from other species lead to early cardiovascular disease. On the other hand, some of the cell lines most frequently used in studying molecular mechanisms of atherosclerosis and assessment of substances with nutritional or pharmacological interest are considered.

  9. Cardiovascular Reactivity and its Association with the Risk of Cardiovascular Morbidity

    Directory of Open Access Journals (Sweden)

    Milagros Lisset León Regal

    2016-06-01

    Full Text Available Background: there are no studies that confirm the association between cardiovascular hyperreactivity and the risk of cardiovascular morbidity. Objective: to determine the association between cardiovascular hyperreactivity and the risk of cardiovascular morbidity in normotensive individuals. Methods: a cross-sectional, correlational study was conducted. The universe consisted of the population aged 15 to 74 years in Cienfuegos municipality; the sample included 644 people. The variables were: sex, skin color, age, total cholesterol, HDL cholesterol, fasting blood glucose, smoking, baseline systolic blood pressure, cardiovascular reactivity, and risk of cardiovascular morbidity. The risk of cardiovascular morbidity was calculated by applying the Framingham Risk Functions. The Pearson’s Chi-square test and the prevalence ratio were used with a 95 % confidence interval. The direction of the relationship between cardiovascular reactivity, age, and systolic blood pressure was analyzed considering the Eta value. Results: the prevalence of cardiovascular hyperreactivity was higher among people aged 65 to 74 years and males. A higher risk of cardiovascular morbidity was observed in cardiovascular hyperreactive individuals. There is an association between non-optimal systolic blood pressure, increasing age, and high risk of cardiovascular morbidity in cardiovascular hyperreactive people. Conclusions: the risk of cardiovascular morbidity is higher in cardiovascular hyperreactive individuals than in normoreactive people. Age and systolic blood pressure showed greater association with high risk of cardiovascular morbidity.

  10. [Secondary nephrotic syndrome due to cardiovascular disease].

    Science.gov (United States)

    Hirayama, Tomoya; Takahashi, Fumihiko; Kikuchi, Kenjiro

    2004-10-01

    Cardiovascular diseases ralely evoke nephrotic syndrome. Especially hypertensive renal disease (nephroscrelosis) and renovascular hypertension occasionally may lead to nephrotic syndrome. We reported a case of nephrotic syndrome with renovascular hypertension successfully treated with candesartan. In eldery patients cardiovascular diseases are appeared. It is very important for clinicians to detect the mechanism of nephrotic syndrome caused by cardiovascular diseases. PMID:15500142

  11. Cardiovascular Magnetic Resonance in Marfan syndrome

    OpenAIRE

    Dormand, Helen; Mohiaddin, Raad H

    2013-01-01

    This review provides an overview of Marfan syndrome with an emphasis on cardiovascular complications and cardiovascular imaging. Both pre- and post-operative imaging is addressed with an explanation of surgical management. All relevant imaging modalities are discussed with a particular focus on cardiovascular MR.

  12. Cardiovascular magnetic resonance in systemic hypertension

    OpenAIRE

    Maceira Alicia M; Mohiaddin Raad H

    2012-01-01

    Abstract Systemic hypertension is a highly prevalent potentially modifiable cardiovascular risk factor. Imaging plays an important role in the diagnosis of underlying causes for hypertension, in assessing cardiovascular complications of hypertension, and in understanding the pathophysiology of the disease process. Cardiovascular magnetic resonance (CMR) provides accurate and reproducible measures of ventricular volumes, mass, function and haemodynamics as well as uniquely allowing tissue char...

  13. Facilitator control as automatic behavior: A verbal behavior analysis

    OpenAIRE

    Hall, Genae A.

    1993-01-01

    Several studies of facilitated communication have demonstrated that the facilitators were controlling and directing the typing, although they appeared to be unaware of doing so. Such results shift the focus of analysis to the facilitator's behavior and raise questions regarding the controlling variables for that behavior. This paper analyzes facilitator behavior as an instance of automatic verbal behavior, from the perspective of Skinner's (1957) book Verbal Behavior. Verbal behavior is autom...

  14. Phytotherapy in Cardiovascular Diseases: From Ethnomedicine to Evidence Based Medicine

    Directory of Open Access Journals (Sweden)

    Ovidiu Burta

    2008-01-01

    Full Text Available Cardiovascular diseases are now considered to be one of the major causes of mortality in the developed and developing world. With the advent of better diagnostic procedures and therapeutic strategies their management has become more efficient, yet the role of herbal and plant remedies is paramount in the developing and remote areas of the world. Phytotherapy or therapeutics using plants and herb based compounds or crude drugs are an indispensable part of Complementary and Alternative Medicine (CAM. The benefits of most of these plants are controversial as their toxicology and pharmacological activities are not well studied and documented. However certain plants species like Ginko biloba and Crataegus have shown promise in experimental and clinical trials. In the present review, some anthropo-geographical and historical perspectives of phytotherapy are mentioned. Some important manifestations of cardiovascular pathology and their phytotherapy are reviewed. The holistic approach of phytotherapy and folkloric ethno medical practices indeed have opened new horizons for quality care in cardiovascular diseases. Phytotherapy and traditional medicine have proven their potential place in the modern and more skeptical evidence based medicine.

  15. Culturally-Inclusive Behavior of Filipino Teachers in International Schools in the Philippines: Perspectives of International Education in a Developing Country

    Science.gov (United States)

    Bernardo, Maria Aurora Correa; Malakolunthu, Suseela

    2013-01-01

    The study explored the culturally inclusive behavior of Filipino teachers using information culled from interviews of six Filipino teachers in international schools on their perception of international education, and how it translates into their pedagogy. The findings of the study reveal inherent patterns of behavior the teachers manifest in…

  16. Hydration state controls stress responsiveness and social behavior

    OpenAIRE

    Krause, Eric G.; de Kloet, Annette D.; Flak, Jonathan N.; Smeltzer, Michael D.; Solomon, Matia B.; Evanson, Nathan K.; Woods, Stephen C; Sakai, Randall R.; Herman, James P.

    2011-01-01

    Life stress frequently occurs within the context of homeostatic challenge, requiring integration of physiological and psychological need into appropriate hormonal, cardiovascular and behavioral responses. To test neural mechanisms underlying stress integration within the context of homeostatic adversity, we evaluated the impact of a pronounced physiological (hypernatremia) challenge on hypothalamic-pituitary-adrenal (HPA), cardiovascular and behavioral responses to an acute psychogenic stress...

  17. Cardiovascular risk, effectiveness and mortality

    Directory of Open Access Journals (Sweden)

    Juan Gérvas

    2011-11-01

    Full Text Available Dice la Ley de Hierro de la Epidemiología que todo el que nace muere. Por ello el fin de la Medicina no es evitar la muerte en sí, sino evitar las muertes, las enfermedades y el sufrimiento médicamente evitables.Al final, todos nuestros pacientes morirán – y nosotros mismos moriremos también, obviamente. “Los cuerpos encuentran una forma de morir” y si la causa no es el hambre ni la deshidratación, ni es congénita, ni infecciosa, ni por lesiones, ni por cáncer, ni por suicidio, tenemos que esperar que sea por ‘causa cardiovascular’, enfermedad pulmonar, insuficiencia renal o hepática, demencia u otras enfermedades degenerativas. Pero de algo tenemos que morir.Morir por causa cardiovascular ni es deshonroso, ni implica defectuosa atención clínica. Que la primera causa de muerte sea la cardiovascular no dice nada respecto a los cuidados clínicos, ni debería asustar.Sin embargo, son evitables muchas muertes de causa cardiovascular. Así, se puede evitar mucha mortalidad cardiovascular disminuyendo la desigualdad social, por ejemplo (con mejor re-distribución de la riqueza, mejor educación y demás. Los médicos saben que los factores adversos psicosociales asociados a la pertenencia a la clase baja responden del 35% del riesgo atribuible a la hipertensión en la incidencia del infarto de miocardio (en otra formulación, que pertenecer a la clase baja multiplica por 2,7 dicho riesgo1.También deberíamos saber que contra las muertes cardiovasculares no hay nada como las políticas de salud pública sobre el tabaquismo (restricciones de lugares en los que fumar, aumento del precio del tabaco, campañas de información, y demás.En lo clínico, las muertes cardiovasculares evitables se deben ver en perspectiva, según lo que se puede lograr2. Así, por 100.000 habitantes y año, el tratamiento con inhibidores de la enzima convertidora de angiotensina (IECA en la insuficiencia cardíaca puede evitar 308 muertes; el consejo m

  18. Nuclear imaging of cardiovascular disease

    International Nuclear Information System (INIS)

    Nuclear imaging methods provide noninvasive indexes of myocardial function, perfusion, and metabolism and are well accepted in clinical cardiology. Advances in prevention and treatment of cardiac disease have resulted in decreasing cardiovascular mortality in industrialized nations. The improvement in therapeutic options has increased the demand for diagnostic tests that might guide clinical decision making. Information beyond the pure anatomic characterization of coronary stenoses is required. Nuclear imaging can be used for early detection and monitoring of the severity and extent of disease. The prognostic potential of such functional testing is being increasingly appreciated and used to guide therapy, thereby resulting in improvement of the quality and cost-effectiveness of the workup of patients with cardiovascular disease. Extensive clinical validation has resulted in growing acceptance of these techniques. Furthermore, ongoing improvement of imaging techniques and development of new radiopharmaceuticals will pave the way for disease-specific, molecular-targeted cardiac imaging in the future. (orig.)

  19. Cardiovascular Prevention of Cognitive Decline

    Directory of Open Access Journals (Sweden)

    Jean-Jacques Monsuez

    2011-01-01

    Full Text Available Midlife cardiovascular risk factors, including diabetes, hypertension, dyslipemia, and an unhealthy lifestyle, have been linked to subsequent incidence, delay of onset, and progression rate of Alzheimer disease and vascular dementia. Conversely, optimal treatment of cardiovascular risk factors prevents and slows down age-related cognitive disorders. The impact of antihypertensive therapy on cognitive outcome in patients with hypertension was assessed in large trials which demonstrated a reduction in progression of MRI white matter hyperintensities, in cognitive decline and in incidence of dementia. Large-scale database correlated statin use and reduction in the incidence of dementia, mainly in patients with documented atherosclerosis, but clinical trials failed to reach similar conclusions. Whether a multitargeted intervention would substantially improve protection, quality of life, and reduce medical cost expenditures in patients with lower risk profile has not been ascertained. This would require appropriately designed trials targeting large populations and focusing on cognitive decline as a primary outcome endpoint.

  20. Psychological hardiness predicts cardiovascular health.

    Science.gov (United States)

    Bartone, Paul T; Valdes, James J; Sandvik, Asle

    2016-09-01

    Many, but not all people experience diminished health, performance and well-being as a function of exposure to stress. However, the underlying neurophysiological processes which characterize hardy or resilient people are not well understood. This study examines psychological hardiness and several indicators of cardiovascular health, including body mass index (BMI) and blood cholesterol markers in a sample of 338 middle-aged adults enrolled in a national security education program. Hierarchical regression analyses reveal that after controlling for the influence of age and sex, high hardiness is related to higher HDL - high density lipoprotein and less body fat (BMI). Lower hardiness is associated with greater total cholesterol to HDL ratio, a cardiovascular disease risk factor. These results suggest that psychological hardiness confers resilience in part through an influence on cholesterol production and metabolism. PMID:26652199

  1. Cardiovascular stress of photochemotherapy (PUVA)

    International Nuclear Information System (INIS)

    The recently devised therapy for psoriasis and related skin diseases, consisting of long-wave ultraviolet light and oral 8-methoxypsoralen (PUVA), was investigated for its cardiovascular effects. In seventeen patients, long-wave ultraviolet light therapy in a treatment enclosure (mean duration, 19.3 minutes) resulted in ambient temperatures of 39.2 degrees C +/- 2.1 degrees C (SD) and skin temperatures of 38.2 degrees C +/- 1.4 degrees C. In upright subjects, heart rate rose 30.8% to 114.4 +/- 25.2 beats per minute (bpm). Intensive room air conditioning, outside of the treatment enclosure, although significantly lowering skin and ambient temperatures, did not affect the heart rates significantly. PUVA therapy is associated with a definite cardiovascular stress when the box type of therapeutic unit is used. Possible modifications are discussed

  2. Ionizing radiation and cardiovascular disease.

    Science.gov (United States)

    Hoel, David G

    2006-09-01

    For more than 15 years the A-bomb survivor studies have shown increased noncancer mortality due to radiation exposures. The most prominent cause of this increase is circulatory disease mortality. Although the estimated relative risk is less than for solid cancers (1.2 versus 1.6 per Sv), there are measurable increases in cardiovascular disease mortality at doses greater than 0.5 Sv. The evidence for circulatory diseases in mortality studies of occupational cohorts exposed to external radiation is less compelling. It is generally accepted that atherosclerosis is an inflammatory disease of the arteries and a risk factor for myocardial infarction. Immunological markers for inflammatory disease have been shown to be dose related in A-bomb survivors. Evidence from animal studies reveals increased cardiovascular mortality and arterial endothelial damage from both neutron and, to a lesser extent, gamma exposures. PMID:17119211

  3. Helicobacter pylori and cardiovascular disease.

    Science.gov (United States)

    Kucukazman, M; Yeniova, O; Dal, K; Yavuz, B

    2015-10-01

    Helicobacter pylori (H. pylori) is one of the most common infections in human. The association between H. pylori and gastrointestinal diseases including peptic ulcer, chronic gastritis, mucosa associated tissue lymphoma (MALT) and gastric cancer is well known. However it was also suggested that H. pylori was linked to various extra-gastrointestinal disorders such as diabetes mellitus and coronary artery disease. In this review we summarized the association between H. pylori and cardiovascular disease. PMID:26502864

  4. Renal Dysfunction and Cardiovascular Disease

    OpenAIRE

    Soveri, Inga

    2006-01-01

    Kidney dysfunction increases cardiovascular disease (CVD) risk. The mechanisms for the risk increase seem to involve a combination of traditional and non-traditional CVD risk factors. We studied renal dysfunction as CVD and mortality risk factor in middle-aged men free from diabetes and CVD. The risk for myocardial infarction (MI) and CVD mortality was increased by ~40% in the 16.5% of men with worse renal function, independent of other CVD risk factors. Renal transplant dysfunction as CVD an...

  5. Cell Therapy for Cardiovascular Regeneration

    OpenAIRE

    Takehara, Naofumi

    2013-01-01

    A great numbers of cardiovascular disease patients all over the world are suffering in the poor outcomes. Under this situation, cardiac regeneration therapy to reorganize the postnatal heart that is defined as a terminal differentiated-organ is a very important theme and mission for human beings. However, the temporary success of several clinical trials using usual cell types with uncertain cell numbers has provided the transient effect of cell therapy to these patients. We therefore should r...

  6. Cardiovascular Function in Pulmonary Emphysema

    OpenAIRE

    Dina Visca; Marina Aiello; Alfredo Chetta

    2013-01-01

    Chronic obstructive pulmonary disease (COPD) and chronic cardiovascular disease, such as coronary artery disease, congestive heart failure, and cardiac arrhythmias, have a strong influence on each other, and systemic inflammation has been considered as the main linkage between them. On the other hand, airflow limitation may markedly affect lung mechanics in terms of static and dynamic hyperinflation, especially in pulmonary emphysema, and they can in turn influence cardiac performance as well...

  7. Platelet proteomics in cardiovascular diseases

    OpenAIRE

    Paula Vélez; Ángel García

    2015-01-01

    In recent years, platelet proteomics has been applied successfully to the study of cardiovascular diseases (CVDs). It is very well known that platelets play a pivotal role in the pathophysiological mechanisms underlying many CVDs, especially acute coronary syndromes (ACSs), since they are implied in thrombus formation after atheroma plaque rupture. This is the reason why molecules involved in platelet activation and aggregation are primary targets for treatment of ACSs. Many efforts are aimed...

  8. Fish Oil in Cardiovascular Prevention

    OpenAIRE

    Alaswad, Khaldoon; Lavie, Carl J.; Milani, Richard V.; O'Keefe, James H

    2002-01-01

    The potential benefits of fish oil have been touted for several decades. The authors review evidence from epidemiologic, retrospective, and controlled prospective clinical trials demonstrating the effects of omega-3 fatty acids (fish oil) for the prevention of major cardiovascular events including myocardial infarction and stroke in primary and especially secondary prevention settings. Fish oil's efficacy in reducing total mortality and sudden cardiac death appears particularly promising, pro...

  9. Perindopril for improving cardiovascular events

    OpenAIRE

    DiNicolantonio, James; O'Keefe, James

    2014-01-01

    James J DiNicolantonio, James H O'Keefe Department of Preventive Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MO, USAIn a recent review in Vascular Health and Risk Management Wang et al state that “In mainly placebo-controlled cardiovascular (CV)-outcome studies in patients with hypertension, CV benefits with perindopril were associated with large reductions in BP.”1 However, perindopril in the European Trial on Reduction of Cardiac Ev...

  10. Perindopril for improving cardiovascular events

    OpenAIRE

    DiNicolantonio JJ; O’Keefe JH

    2014-01-01

    James J DiNicolantonio, James H O'Keefe Department of Preventive Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MO, USAIn a recent review in Vascular Health and Risk Management Wang et al state that “In mainly placebo-controlled cardiovascular (CV)-outcome studies in patients with hypertension, CV benefits with perindopril were associated with large reductions in BP.”1 However, perindopril in the European Trial on Reduction of Cardiac Events With Perind...

  11. Genetic risks for cardiovascular diseases

    OpenAIRE

    Zafarmand, M. H.

    2008-01-01

    Atherosclerotic cardiovascular disease (CVD), which involves the heart, brain, and peripheral circulation, is a major health problem world-wide. The development of atherosclerosis is a complex process, and several established risk factors are involved. Nevertheless, these established risk factors do not fully explain the occurrence of CVD and further insight is required in factors such as genetic determinants that may identify individuals at risk. In this thesis we worked on the genetic basis...

  12. Cardiovascular Effects of Antidepressants and Mood Stabilizers

    Directory of Open Access Journals (Sweden)

    Shahin Akhondzadeh

    2007-08-01

    Full Text Available Depression is a serious disorder in today’s society, with the estimates of lifetime prevalence being as high as 21% of the general population in some developed countries. As defined by the American Psychiatric Association, depression is a heterogeneous disorder often manifested with symptoms at the psychological, behavioral, and physiological levels. Such patients are often reluctant to take synthetic antidepressants in their appropriate doses due to their anticipated side effects including inability to drive a car, dry mouth, constipation, and sexual dysfunction. As a therapeutic alternative, effective herbal drugs may offer advantages in terms of safety and tolerability, possibly also improving patient compliance. The advent of the first antidepressants, Monoamine Oxidase Inhibitors (MAOIs and Tricyclic Antidepressants (TCAs, in the 1950s and 1960s represented a dramatic leap forward in the clinical management of depression. The subsequent development of the Selective Serotonin Reuptake Inhibitors (SSRIs and the Serotonin Norepinephrine Reuptake Inhibitor (SNRI venlafaxine in the past decade and a half has greatly enhanced the treatment of depression by offering patients medications that are as effective as the older agents but are generally more tolerable and safer in an overdose. The introduction of atypical antidepressants, such as bupropion, nefazadone, and mirtazapine, has added substantially to the available pharmacopoeia for depression. Nonetheless, rates of remission tend to be low and the risk of relapse and recurrence remains high. One of the concerns regarding the safety of antidepressant is its potential risk of cardiotoxicity and cardiovascular side effects. In this review, we will focus on the cardiovascular side effects of different types of antidepressants.

  13. Cardiovascular complications of radiation exposure.

    Science.gov (United States)

    Finch, William; Shamsa, Kamran; Lee, Michael S

    2014-01-01

    The cardiovascular sequelae of radiation exposure are an important cause of morbidity and mortality following radiation therapy for cancer, as well as after exposure to radiation after atomic bombs or nuclear accidents. In the United States, most of the data on radiation-induced heart disease (RIHD) come from patients treated with radiation therapy for Hodgkin disease and breast cancer. Additionally, people exposed to radiation from the atomic bombs in Hiroshima and Nagasaki, Japan, and the Chernobyl, Ukraine, nuclear accident have an increased risk of cardiovascular disease. The total dose of radiation, as well as the fractionation of the dose, plays an important role in the development of RIHD. All parts of the heart are affected, including the pericardium, vasculature, myocardium, valves, and conduction system. The mechanism of injury is complex, but one major mechanism is injury to endothelium in both the microvasculature and coronary arteries. This likely also contributes to damage and fibrosis within the myocardium. Additionally, various inflammatory and profibrotic cytokines contribute to injury. Diagnosis and treatment are not significantly different from those for conventional cardiovascular disease; however, screening for heart disease and lifelong cardiology follow-up is essential in patients with past radiation exposure. PMID:25290729

  14. Perindopril for improving cardiovascular events

    Directory of Open Access Journals (Sweden)

    DiNicolantonio JJ

    2014-08-01

    Full Text Available James J DiNicolantonio, James H O'Keefe Department of Preventive Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, MO, USAIn a recent review in Vascular Health and Risk Management Wang et al state that “In mainly placebo-controlled cardiovascular (CV-outcome studies in patients with hypertension, CV benefits with perindopril were associated with large reductions in BP.”1 However, perindopril in the European Trial on Reduction of Cardiac Events With Perindopril in Stable Coronary Artery Disease (EUROPA study significantly reduced major cardiovascular events despite a small reduction (approximately 4 mmHg in systolic blood pressure from baseline.2,3 Additionally, the average baseline blood pressure in the EUROPA was just 137/82 mmHg, and in those without hypertension, perindopril still provided a 20% reduction in the combined endpoint of cardiovascular death, myocardial infarction, and cardiac arrest.4,5 In fact, patients receiving perindopril with a baseline systolic blood pressure of <120 mmHg had the greatest reduction in the primary event.6 View original paper by Wang and colleagues. 

  15. Robotic technology in cardiovascular medicine.

    Science.gov (United States)

    Bonatti, Johannes; Vetrovec, George; Riga, Celia; Wazni, Oussama; Stadler, Petr

    2014-05-01

    Robotic technology has been used in cardiovascular medicine since the late 1990s. Interventional cardiology, electrophysiology, endovascular surgery, minimally invasive cardiac surgery, and laparoscopic vascular surgery are all fields of application. Robotic devices enable endoscopic reconstructive surgery in narrow spaces and fast, very precise placement of catheters and devices in catheter-based interventions. In all robotic systems, the operator manipulates the robotic arms from a control station or console. In the field of cardiac surgery, mitral valve repair, CABG surgery, atrial septal defect repair, and myxoma resection can be achieved using robotic technology. Furthermore, vascular surgeons can perform a variety of robotically assisted operations to treat aortic, visceral, and peripheral artery disease. In electrophysiology, ablation procedures for atrial fibrillation can be carried out with robotic support. In the past few years, robotically assisted percutaneous coronary intervention and abdominal aortic endovascular surgery techniques have been developed. The basic feasibility and safety of robotic approaches in cardiovascular medicine has been demonstrated, but learning curves and the high costs associated with this technology have limited its widespread use. Nonetheless, increased procedural speed, accuracy, and reduced exposure to radiation and contrast agent in robotically assisted catheter-based interventions, as well as reduced surgical trauma and shortened patient recovery times after robotic cardiovascular surgery are promising achievements in the field. PMID:24663088

  16. Ácidos graxos e doenças cardiovasculares: uma revisão Fatty acids and cardiovascular diseases: a review

    Directory of Open Access Journals (Sweden)

    Flávia Emília Leite de LIMA

    2000-08-01

    Full Text Available Nas últimas décadas a prevalência de doenças cardiovasculares tem aumentado progressivamente, tornando-se um grave problema de saúde pública. Alguns estudos têm demonstrado haver uma associação positiva entre a ingestão de gordura saturada e a prevalência dessas doenças, bem como uma associação negativa com a ingestão de gorduras insaturadas. Esses conhecimentos motivaram uma evolução nas recomendações dos ácidos graxos, visando melhor utilização destes e respeitando-se uma proporção adequada na dieta, a fim de diminuir a prevalência das doenças cardiovasculares. Este trabalho tem como objetivo realizar uma revisão da literatura médica sobre os estudos desenvolvidos com ácidos graxos e seus possíveis efeitos em doenças cardiovasculares, bem como evolução de suas recomendações através do tempo, tendências de consumo e perspectivas futuras.During the last decades the prevalence of cardiovascular diseases has increased progressively, becoming a serious public health problem. Some studies have shown a positive association between saturated fatty acid intake and the prevalence of cardiovascular diseases, and a negative association with unsaturated fatty acids intake. These studies indicate a need to evaluate the different kinds of fatty acids (saturated, monounsaturated and polyunsaturated and their effects, aiming at a better utilization and maintaining a suitable proportion in the diet in order to diminish the incidence of cardiovascular diseases. The objective of this paper is to accomplish a review of the medical literature regarding fatty acids and their effects on cardiovascular diseases, as well as the evolution of their requirements through time, consumption trends and future perspectives.

  17. International Perspectives.

    Science.gov (United States)

    Allen, Kenn; Habermann, Ulla; Chowdhury, Omar Faruque; Guerra, Iraida Manzanilla

    1998-01-01

    Includes "Introduction to International Perspectives" (Allen); "Volunteerism in the Welfare State: The Case of Denmark" (Habermann); "Grassroots Organizing in Bangladesh" (Chowdhury); and "Volunteerism in Latin America" (Guerra). (SK)

  18. Risco cardiovascular, efetividade e mortalidade Cardiovascular risk, effectiveness and mortality Riesgo cardiovascular, efectividad y mortalidad

    Directory of Open Access Journals (Sweden)

    Juan Gérvas

    2012-02-01

    Full Text Available

    A Lei de Ferro da Epidemiologia (Ley de Hierro de La Epidemiología diz que todos que nascem, morrem. Por isso, o propósito da Medicina não é evitar a morte por si só, mas evitar as mortes, as doenças e o sofrimento que podem ser medicamente evitáveis.

    No final, todos nossos pacientes morrerão – e nós também, obviamente, morreremos. “Os corpos encontram uma forma de morrer”, e se a causa não for por fome ou desidratação, por motivo congênito e infeccioso, por lesões, câncer ou suicídio, temos que esperar que seja por ‘motivo cardiovascular’, doença pulmonar, insuficiência renal ou hepática, demência ou outras doenças degenerativas. Mas temos que morrer por alguma coisa.

    Morrer por causa cardiovascular não é desonroso, nem refere-se à atenção clínica imperfeita. O fato de a primeira causa de morte ser a cardiovascular não tem nenhuma relação com os cuidados clínicos e nem deveria assustar.

    Entretanto, muitas das mortes por motivo cardiovascular poderiam ser evitadas. Assim, poder-se-ia evitar mortalidade cardiovascular, diminuindo a desigualdade social, por exemplo, com melhor redistribuição da riqueza, melhor educação etc. Os médicos sabem que os fatores adversos psicossociais associados ao fato de pertencer à classe baixa correspondem a 35% do risco atribuído à hipertensão na incidência do infarto do miocárdio (em outra hipótese, pertencer à classe baixa duplica 2,7 tal risco1.

    Também deve-se saber que, contra as mortes cardiovasculares, não há nada como as políticas de saúde pública quanto ao tabagismo (restrições dos lugares onde fumar, aumento do preço do tabaco, campanhas de informação, entre outras.

    Na parte clínica, as mortes cardiovasculares evitáveis devem ser vistas em perspectiva, de acordo com o que seja possível conseguir2. Portanto, por 100.000 habitantes ao ano, o tratamento com inibidores da enzima conversora de angiotensina (IECA

  19. Evolutionary perspectives on emotions and their link to intentions, dispositions and behavior. Comment on "The quartet theory of human emotions: An integrative and neurofunctional model" by S. Koelsch et al.

    Science.gov (United States)

    Wildgruber, Dirk; Kreifelts, Benjamin

    2015-06-01

    Koelsch and coworkers present a sophisticated neuroanatomical model of emotions comprising four affect-systems and four output-systems, each bound to a specific brain area [1]. Moreover, they suggest the emergence of distinct components of subjective feelings or "emotion percepts" due to integration of the activation across these subsystems. Incorporating numerous neurobiological, psychological and philosophical findings on human emotions, the model reflects an extensive interdisciplinary approach. Considering an evolutionary perspective, however, we would like to address some issues concerning emotions and their link to intentions, dispositions and behavior that are not fully covered by the Quartet Model. Charles Darwin pointed out that individuals that are better adapted to their environment have increased chances of survival and reproduction. Therefore, natural selection leads to a rising prevalence of properties offering a survival benefit across generations [2]. To better understand the biological functions of emotions we propose to ask the question: How do emotions provide a benefit for survival and reproduction?

  20. Nutrition and Cardiovascular Disease: Finding the Perfect Recipe for Cardiovascular Health

    Directory of Open Access Journals (Sweden)

    Alice Ravera

    2016-06-01

    Full Text Available The increasing burden of cardiovascular disease (CVD despite the progress in management entails the need of more effective preventive and curative strategies. As dietary-associated risk is the most important behavioral factor influencing global health, it appears the best target in the challenge against CVD. Although for many years, since the formulation of the cholesterol hypothesis, a nutrient-based approach was attempted for CVD prevention and treatment, in recent years a dietary-based approach resulted more effective in reducing cardiovascular risk worldwide. After the publication of randomized trials on the remarkable effects of the Mediterranean diet and the Dietary Approach to Stop Hypertension (DASH diet on CVD, new efforts were put on research about the effects of complex dietary interventions on CVD. The purpose of this paper is to review the evidence on dietary interventions in the prevention and disease modification of CVD, focusing on coronary artery disease and heart failure, the main disease responsible for the enormous toll taken by CVD worldwide.

  1. Cost-effectiveness of the diabetes care protocol, a multifaceted computerized decision support diabetes management intervention that reduces cardiovascular risk

    NARCIS (Netherlands)

    F.G.W. Cleveringa (Frits G.); P.M.J. Welsing (Paco); M. van den Donk (Maureen); K.J. Gorter; L.W. Niessen (Louis Wilhelmus); G.E.H.M. Rutten (Guy); W.K. Redekop (Ken)

    2010-01-01

    textabstractOBJECTIVE- The Diabetes Care Protocol (DCP), a multifaceted computerized decision support diabetes management intervention, reduces cardiovascular risk of type 2 diabetic patients. We performed a cost-effectiveness analysis of DCP from a Dutch health care perspective. RESEARCH DESIGN AND

  2. Cost-Effectiveness of the Diabetes Care Protocol, a Multifaceted Computerized Decision Support Diabetes Management Intervention That Reduces Cardiovascular Risk

    NARCIS (Netherlands)

    Cleveringa, Frits G. W.; Welsing, Paco M. J.; van den Donk, Maureen; Gorter, Kees J.; Niessen, Louis W.; Rutten, Guy E. H. M.; Redekop, William K.

    2010-01-01

    OBJECTIVE - The Diabetes Care Protocol (DCP), a multifaceted Computerized decision support diabetes management intervention, reduces cardiovascular risk Of type 2 diabetic patients. We performed a cost-effectiveness analysis of DCP from a Dutch health care perspective. RESEARCH DESIGN AND METHODS -

  3. Behavioral Counseling to Promote a Healthful Diet and Physical Activity for CVD Prevention in Adults with Risk Factors

    Science.gov (United States)

    Understanding Task Force Recommendations Behavioral Counseling to Promote a Healthful Diet and Physical Activity for Cardiovascular Disease Prevention in Adults with Cardiovascular Risk Factors The U.S. Preventive ...

  4. Cardiovascular Risk Surveillance to Develop a Nationwide Health Promotion Strategy

    Science.gov (United States)

    Bansilal, Sameer; Vedanthan, Rajesh; Woodward, Mark; Iyengar, Rupa; Hunn, Marilyn; Lewis, Marcelle; Francis, Lesley; Charney, Alexander; Graves, Claire; Farkouh, Michael E.; Fuster, Valentin

    2015-01-01

    OBJECTIVE The Grenada Heart Project aims to study the clinical, biological, and psychosocial determinants of the cardiovascular health in Grenada in order to develop and implement a nationwide cardiovascular health promotion program. METHODS We recruited 2,827 adults randomly selected from the national electronic voter list. The main outcome measures were self-reported cardiovascular disease and behavioral risk factors, anthropometric measures, blood pressure, point-of-care testing for glucose and lipids, and ankle-brachial index. Risk factors were also compared with the U.S. National Health and Nutritional Survey data. RESULTS Prevalence of cardiovascular disease risk factors were: overweight and obesity—57.7% of the population, physical inactivity—23.4%, diabetes—13.3%, hypertension—29.7%, hypercholesterolemia—8.6%, and smoking—7%. Subjects who were physically active had a significantly lower 10-year Framingham risk score (p < 0.001). Compared with the U.S. National Health and Nutrition Survey data, Grenadian women had higher rates of adiposity, diabetes, hypertension, and elevated low-density lipoprotein cholesterol, whereas Grenadian men had a higher rate of diabetes, a similar rate of hypertension, and lower rates of the other risk factors. Prevalence of peripheral arterial disease was 7.6%; stroke and coronary heart disease were equally prevalent at ~2%. CONCLUSION This randomly selected adult sample in Grenada reveals prevalence rates of obesity, hypertension, and diabetes significantly exceeding those seen in the United States. The contrasting, paradoxically low levels of prevalent cardiovascular disease support the concept that Grenada is experiencing an obesity-related “risk transition.” These data form the basis for the implementation of a pilot intervention program based on the Institute of Medicine recommendations and may serve as a model for other low- and middle-income countries. PMID:25691303

  5. Influence of Fear Stress on Cardiovascular System and Behaviors in Rats.%恐惧应激对大鼠心血管系统及一般行为的影响

    Institute of Scientific and Technical Information of China (English)

    刘佳佳; 严进; 郑冬梅; 唐云翔; 潘霄

    2011-01-01

    目的 观察恐惧应激对大鼠血压、心率及一般行为的影响.方法 采用条件恐惧应激模型,将64只成年雄性Wistar大鼠随机分为恐惧应激模型组、对照组.通过对大鼠恐惧行为的观察、自发活动试验的测定,动态观察两组大鼠在不同恐惧应激时期行为学方面的变化;通过无创尾动脉测压法,观察不同恐惧应激时程大鼠血压及心率的变化;采用放射免疫学方法测定大鼠在不同恐惧应激时程血清中肌钙蛋白I浓度的变化.结果 恐惧组大鼠冻结时间显著高于对照组(t=5.700,P<0.01);恐惧应激组体重在第2周以后增加显著低于对照组(t=2.675,t=2.316;P<0.05;t=3.930,P<0.01);自发活动中恐惧应激组活动次数显著低于对照组(t=2.267,P<0.05;t=2.990,t=3.325;P<0.01;t=2.423,P<0.05);恐惧应激组自发活动中休息时间显著高于对照组(t=2.621,P<0.05;t=3.356,P<0.01;t=2.668,P<0.05;t=2.384,P<0.05);随着应激时程的增加条件恐惧应激组血压显著高于对照组(第2周t=2.887,P<0.05;第3周t=4.263,P<0.01;第4周t=4.414,P<0.01);恐惧模型组心率与对照组相比显著升高(第2周t=2.382,P<0.05;第3周t=1.996,P<0.05;第4周t=1.881,P<0.05);条件恐惧应激模型组大鼠血清cTnl浓度显著高于对照组(第1周t=2.147,P<0.05;第2周t=3.479,P<0.01;第3周t=3.402,P<0.01;第4周t=3.863,P<0.01).结论 条件恐惧应激对大鼠血压、心率、体重、一般活动、血清cTnl都有明显影响.%Objective To observe influence of fear stress on blood pressure, heart rate and behavior in rats. Methods The experiment was carried out with conditioned fear stress model, 64 adult male wistar rats were divided into fear stress model group and control group. The behavior changes of the rats at different times of fear stress were observed by observing the fear behaviors and testing spontaneous activity, the changes of blood pressure and heart rate were observed by noninvasive manometry, the cardiac troponin Ⅰ (c

  6. Cardiovascular Actions and Therapeutic Potential of Tetramethylpyrazine (Active Component Isolated from Rhizoma Chuanxiong): Roles and Mechanisms

    Science.gov (United States)

    Guo, Ming; Liu, Yue; Shi, Dazhuo

    2016-01-01

    Tetramethylpyrazine (TMP), a pharmacologically active component isolated from the rhizome of the Chinese herb Rhizoma Chuanxiong (Chuanxiong), has been clinically used in China and Southeast Asian countries for the prevention and treatment of cardiovascular diseases (CVDs) for about fifty years. The pharmacological effects of TMP on the cardiovascular system have attracted great interest. Emerging experimental studies and clinical trials have demonstrated that TMP prevents atherosclerosis as well as ischemia-reperfusion injury. The cardioprotective effects of TMP are mainly related to its antioxidant, anti-inflammatory, or calcium-homeostasis effects. This review focuses on the roles and mechanisms of action of TMP in the cardiovascular system and provides a novel perspective on TMP's clinical use. PMID:27314011

  7. Collaborative research in cardiovascular dynamics and bone elasticity

    Science.gov (United States)

    1974-01-01

    A collaborative research program covering a variety of topics of biomechanics and biomedical engineering within the fields of cardiovascular dynamics, respiration, bone elasticity and vestibular physiology is described. The goals of the research were to promote: (1) a better understanding of the mechanical behavior of the circulatory system and its control mechanisms; (2) development of noninvasive methods of measuring the changes in the mechanical properties of blood vessels and other cardiovascular parameters in man; (3) application of these noninvasive methods to examine in man the physiological effects of environmental changes, including earth-simulated gravitational changes; and (4) development of in-flight methods for studying the events which lead to post-flight postural hypotension.

  8. Regenerative cell therapy and pharmacotherapeutic intervention in heart failure Part 2 : Pharmacological targets, agents and intervention perspectives

    NARCIS (Netherlands)

    Qian, C.; Schoemaker, R. G.; van Gilst, W. H.; Yu, B.; Roks, A. J. M.

    2008-01-01

    Regenerative medicine represents a promising perspective on therapeutic angiogenesis in patients with cardiovascular disease, including heart failure. However, previous or ongoing clinical trials show ambiguous outcomes with respect to the benefit of regenerative therapy by means of bone marrow stem

  9. Cardiovascular functioning, personality, and the social world: the domain of hierarchical power.

    Science.gov (United States)

    Newton, Tamara L

    2009-02-01

    The present paper considers connections between cardiovascular functioning (i.e., disease status and acute stress responses) and social dominance, and its counterpart, social submissiveness, both of which are part of the broader domain of "hierarchical power" [Bugental, D.B., 2000. Acquisition of the algorithms of social life: a domain-based approach. Psychological Bulletin 126, 187-219]. Empirical research on connections between dominance/submissiveness and cardiovascular morbidity and mortality in humans is reviewed, as is research on dominance/submissiveness and cardiovascular reactivity to, and recovery from, acute stressors. Three general conclusions are established. First, in both cross-sectional and longitudinal investigations, trait and behavioral indicators of dominance have been positively associated with cardiovascular disease severity, incidence, and progression, whereas preliminary evidence from two studies suggests that trait submissiveness may protect against poorer disease outcomes. Second, among men and women, trait dominance is associated with reactivity to and recovery from acute stressors, particularly social challenges. Third, linkages between dominance/submissiveness and cardiovascular functioning, especially cardiovascular reactivity, are characterized by gender-specific patterning, and this patterning emerges as a function of social context. Implications for the next generation of research concerning social dominance, gender, and cardiovascular functioning are discussed. PMID:18706926

  10. Wearable Wireless Cardiovascular Monitoring Using Textile-Based Nanosensor and Nanomaterial Systems

    Directory of Open Access Journals (Sweden)

    Prashanth Shyamkumar

    2014-08-01

    Full Text Available Wearable and ultraportable electronics coupled with pervasive computing are poised to revolutionize healthcare services delivery. The potential cost savings in both treatment, as well as preventive care are the focus of several research efforts across the globe. In this review, we describe the motivations behind wearable solutions to real-time cardiovascular monitoring from a perspective of current healthcare services, as well as from a systems design perspective. We identify areas where emerging research is underway, namely: nanotechnology in textile-based wearable monitors and healthcare solutions targeted towards smart devices, like smartphones and tablets.

  11. Cardiovascular Health Status by Occupational Group - 21 States, 2013.

    Science.gov (United States)

    Shockey, Taylor M; Sussell, Aaron L; Odom, Erika C

    2016-01-01

    Cardiovascular disease (CVD) accounts for one of every three deaths in the United States, making it the leading cause of mortality in the country (1). The American Heart Association established seven ideal cardiovascular health behaviors or modifiable factors to improve CVD outcomes in the United States. These cardiovascular health metrics (CHMs) are 1) not smoking, 2) being physically active, 3) having normal blood pressure, 4) having normal blood glucose, 5) being of normal weight, 6) having normal cholesterol levels, and 7) eating a healthy diet (2). Meeting six or all seven CHMs is associated with a lower risk for all-cause, CVD, and ischemic heart disease mortalities compared with the risk to persons who meet none or only one CHM (3). Fewer than 2% of U.S. adults meet all seven of the American Heart Association's CHMs (4). Cardiovascular morbidity and mortality account for an estimated annual $120 billion in lost productivity in the workplace; thus, workplaces are viable settings for effective health promotion programs (5). With over 130 million employed persons in the United States, accounting for about 55% of all U.S. adults, the working population is an important demographic group to evaluate with regard to cardiovascular health status. To determine if an association between occupation and CHM score exists, CDC analyzed data from the 2013 Behavioral Risk Factor Surveillance System (BRFSS) industry and occupation module, which was implemented in 21 states. Among all occupational groups, community and social services employees (14.6%), transportation and material moving employees (14.3%), and architecture and engineering employees (11.6%) had the highest adjusted prevalence of meeting two or fewer CHMs. Transportation and material moving employees also had the highest prevalence of "not ideal" ("0" [i.e., no CHMs met]) scores for three of the seven CHMs: physical activity (54.1%), blood pressure (31.9%), and weight (body mass index [BMI]; 75.5%). Disparities

  12. Circadian misalignment increases cardiovascular disease risk factors in humans.

    Science.gov (United States)

    Morris, Christopher J; Purvis, Taylor E; Hu, Kun; Scheer, Frank A J L

    2016-03-01

    Shift work is a risk factor for hypertension, inflammation, and cardiovascular disease. This increased risk cannot be fully explained by classic risk factors. One of the key features of shift workers is that their behavioral and environmental cycles are typically misaligned relative to their endogenous circadian system. However, there is little information on the impact of acute circadian misalignment on cardiovascular disease risk in humans. Here we show-by using two 8-d laboratory protocols-that short-term circadian misalignment (12-h inverted behavioral and environmental cycles for three days) adversely affects cardiovascular risk factors in healthy adults. Circadian misalignment increased 24-h systolic blood pressure (SBP) and diastolic blood pressure (DBP) by 3.0 mmHg and 1.5 mmHg, respectively. These results were primarily explained by an increase in blood pressure during sleep opportunities (SBP, +5.6 mmHg; DBP, +1.9 mmHg) and, to a lesser extent, by raised blood pressure during wake periods (SBP, +1.6 mmHg; DBP, +1.4 mmHg). Circadian misalignment decreased wake cardiac vagal modulation by 8-15%, as determined by heart rate variability analysis, and decreased 24-h urinary epinephrine excretion rate by 7%, without a significant effect on 24-h urinary norepinephrine excretion rate. Circadian misalignment increased 24-h serum interleukin-6, C-reactive protein, resistin, and tumor necrosis factor-α levels by 3-29%. We demonstrate that circadian misalignment per se increases blood pressure and inflammatory markers. Our findings may help explain why shift work increases hypertension, inflammation, and cardiovascular disease risk. PMID:26858430

  13. Positive Behavior Support and Applied Behavior Analysis: A Familial Alliance

    Science.gov (United States)

    Dunlap, Glen; Carr, Edward G.; Horner, Robert H.; Zarcone, Jennifer R.; Schwartz, Ilene

    2008-01-01

    Positive behavior support (PBS) emerged in the mid-1980s as an approach for understanding and addressing problem behaviors. PBS was derived primarily from applied behavior analysis (ABA). Over time, however, PBS research and practice has incorporated evaluative methods, assessment and intervention procedures, and conceptual perspectives associated…

  14. Myocardial first-pass perfusion cardiovascular magnetic resonance: history, theory, and current state of the art

    OpenAIRE

    Axel Leon; Ferreira Pedro; Epstein Frederick H; Nayak Krishna; Raman Subha V; Gerber Bernhard L; Kraitchman Dara L

    2008-01-01

    Abstract In less than two decades, first-pass perfusion cardiovascular magnetic resonance (CMR) has undergone a wide range of changes with the development and availability of improved hardware, software, and contrast agents, in concert with a better understanding of the mechanisms of contrast enhancement. The following review provides a perspective of the historical development of first-pass CMR, the developments in pulse sequence design and contrast agents, the relevant animal models used in...

  15. Cross-Sectional Association between the Number of Missing Teeth and Cardiovascular Disease among Adults Aged 50 or Older: BRFSS 2010

    OpenAIRE

    R. Constance Wiener; Usha Sambamoorthi

    2014-01-01

    Objective. The relationship between oral health and cardiovascular disease is an emerging area of research. The objective of the current study is to evaluate the association of cardiovascular disease and the number of missing teeth as a risk indicator. Methods. Cross-sectional study design with data on 275,424 respondents aged 50 or older from the 2010 Behavioral Risk Factor Surveillance System survey was used. The dependent variable was self-reported cardiovascular disease. The association...

  16. Positive Cardiovascular Health: A Timely Convergence.

    Science.gov (United States)

    Labarthe, Darwin R; Kubzansky, Laura D; Boehm, Julia K; Lloyd-Jones, Donald M; Berry, Jarett D; Seligman, Martin E P

    2016-08-23

    Two concepts, positive health and cardiovascular health, have emerged recently from the respective fields of positive psychology and preventive cardiology. These parallel constructs are converging to foster positive cardiovascular health and a growing collaboration between psychologists and cardiovascular scientists to achieve significant improvements in both individual and population cardiovascular health. We explore these 2 concepts and note close similarities in the measures that define them, the health states that they aim to produce, and their intended long-term clinical and public health outcomes. We especially examine subjective health assets, such as optimism, that are a core focus of positive psychology, but have largely been neglected in preventive cardiology. We identify research to date on positive cardiovascular health, discuss its strengths and limitations thus far, and outline directions for further engagement of cardiovascular scientists with colleagues in positive psychology to advance this new field. PMID:27539179

  17. National Institutes of Health Career Development Awards for Cardiovascular Physician-Scientists: Recent Trends and Strategies for Success.

    Science.gov (United States)

    Lindman, Brian R; Tong, Carl W; Carlson, Drew E; Balke, C William; Jackson, Elizabeth A; Madhur, Meena S; Barac, Ana; Abdalla, Marwah; Brittain, Evan L; Desai, Nihar; Kates, Andrew M; Freeman, Andrew M; Mann, Douglas L

    2015-10-20

    Nurturing the development of cardiovascular physician-scientist investigators is critical for sustained progress in cardiovascular science and improving human health. The transition from an inexperienced trainee to an independent physician-scientist is a multifaceted process requiring a sustained commitment from the trainee, mentors, and institution. A cornerstone of this training process is a career development (K) award from the National Institutes of Health (NIH). These awards generally require 75% of the awardee's professional effort devoted to research aims and diverse career development activities carried out in a mentored environment over a 5-year period. We report on recent success rates for obtaining NIH K awards, provide strategies for preparing a successful application and navigating the early career period for aspiring cardiovascular investigators, and offer cardiovascular division leadership perspectives regarding K awards in the current era. Our objective is to offer practical advice that will equip trainees considering an investigator path for success. PMID:26483107

  18. Liver function tests: Association with cardiovascular outcomes

    OpenAIRE

    2010-01-01

    An association between nonalcoholic fatty liver disease and cardiovascular disease has been repeatedly reported. Several studies have focused on levels of gamma-glutamyltransferase (GGT) and alanine aminotransferase (ALT) in relation to cardiovascular outcomes. Evidence indicates that GGT may have a potential role for cardiovascular risk stratification while the role of ALT for cardiac prognosis remains controversial. A conceptual framework that includes not only GGT and ALT but also markers ...

  19. Astaxanthin in Cardiovascular Health and Disease

    OpenAIRE

    Fassett, Robert G; Coombes, Jeff S

    2012-01-01

    Oxidative stress and inflammation are established processes contributing to cardiovascular disease caused by atherosclerosis. However, antioxidant therapies tested in cardiovascular disease such as vitamin E, C and β-carotene have proved unsuccessful at reducing cardiovascular events and mortality. Although these outcomes may reflect limitations in trial design, new, more potent antioxidant therapies are being pursued. Astaxanthin, a carotenoid found in microalgae, fungi, complex plants, seaf...

  20. Reactive Oxygen Species in Cardiovascular Disease

    OpenAIRE

    Sugamura, Koichi; Keaney, John F.

    2011-01-01

    Based on the ‘free-radical theory’ of disease, researchers have been trying to elucidate the role of oxidative stress from free radicals in cardiovascular disease. Considerable data indicate that ROS and oxidative stress are important features of cardiovascular diseases including atherosclerosis, hypertension, and congestive heart failure. However, blanket strategies with antioxidants to ameliorate cardiovascular disease have not generally yielded favorable results. However, our understanding...

  1. Cardiovascular Disease, Mitochondria, and Traditional Chinese Medicine

    OpenAIRE

    Jie Wang; Fei Lin; Li-li Guo; Xing-jiang Xiong; Xun Fan

    2015-01-01

    Recent studies demonstrated that mitochondria play an important role in the cardiovascular system and mutations of mitochondrial DNA affect coronary artery disease, resulting in hypertension, atherosclerosis, and cardiomyopathy. Traditional Chinese medicine (TCM) has been used for thousands of years to treat cardiovascular disease, but it is not yet clear how TCM affects mitochondrial function. By reviewing the interactions between the cardiovascular system, mitochondrial DNA, and TCM, we sho...

  2. Cardiovascular responses to hypogravic environments

    Science.gov (United States)

    Sandler, H.

    1983-01-01

    The cardiovascular deconditioning observed during and after space flight is characterized in a review of human space and simulation studies and animal simulations. The various simulation techniques (horizontal bed rest, head-down tilt, and water immersion in man, and immobilization of animals) are examined, and sample results are presented in graphs. Countermeasures such as exercise regimens, fluid replacement, drugs, venous pooling, G-suits, oscillating beds, electrostimulation of muscles, lower-body negative pressure, body-surface cooling, and hypoxia are reviewed and found to be generally ineffective or unreliable. The need for future space experimentation in both humans and animals is indicated.

  3. Riesgo cardiovascular en la mujer

    OpenAIRE

    Claver García, Laura

    2014-01-01

    La enfermedad cardiovascular siempre ha sido considerada una enfermedad de hombres. Sin embargo, existen datos que reflejan el aumento de esta patología en las mujeres, alcanzando e incluso superando al número de varones, y llegando a ser en España la primera causa de muerte. En ellas, estos episodios suelen comenzar 10 años más tarde debido a la protección que durante la etapa fértil brindan los estrógenos. Sin embargo, tras la menopausia los niveles de estas hormonas disminuyen y es ent...

  4. Image processing in cardiovascular radiology

    International Nuclear Information System (INIS)

    In the past ten years digital image processing has contributed decisively to the advance of cardiovascular radiology. Not only images of better diagnostic value could be produced, but also in many cases the risk for the patient was diminished. In this paper three topics are discussed: One of the principal methods is digital angiography especially with functional imaging. In addition, because of the rapid progress of digital imaging data compression became a major issue. Finally there is a good chance that 3D-processing of MRI data will at least partly replace the present invasive techniques

  5. [Cognitive dysfunction in cardiovascular diseases].

    Science.gov (United States)

    Ladwig, Karl-Heinz

    2016-08-01

    A multitude of modifiable risk factors during the median phase of life are often causative for cognitive dysfunction (CD) in old age. High evidence exists for cigarette smoking, diabetes, physical inactivity and sleeping disorders. Single large scale population based studies proof it for hypertension, hypercholesterinemia and depression, conflicting evidence exists for obesity and work stress. Little attention is paid to the close association between cardiovascular disease conditions and CD, particularly for atrial fibrillation, heart failure and for older patients with coronary heart disease. Undetected CD may be responsible for non-adherence and failure of self-care programs in chronic heart patients. PMID:27557067

  6. 军队干部缺血性心血管病高危人群健康行为现状及影响因素%Health Behaviors Status of High Risk Population with Ischemic Cardiovascular Disease in Military Cadres and Its Influential Factors

    Institute of Scientific and Technical Information of China (English)

    陈立; 夏季平; 高永喜; 刘朝华

    2011-01-01

    [Objective] To understand the health behaviors status of high risk population with ischemic cardiovascular disease(ICVD) in military cadres and its influential factors. [Methods] The related factors of ICVD in military cadres aged 35~59 years old in a local army were surveyed with a questionnaire. Health promoting lifestyle profile Ⅱ (HPLP Ⅱ ) was used in the health behavior questionnaire survey of coronary heart disease. [Results] Of all 977 subjects, 81 persons(8.29%) were high risk ICVD population. The total scores of health behavior ( P = 0. 028) and its three dimension such as health responsibility( P= 0. 002), sport and exercise( P= 0. 038) and nutrition( P=0. 033) in high risk ICVD group were obviously lower than those in normal control group. The general demographic factors such as age( P=0. 001), marital status( P= 0. 002), job type( P=0. 000) and family income( P= 0. 000) of high risk population had obvious influence on their health behavior. [Conclusion] High risk ICVD population in military cadres have lower level of health behavior. Appropriate measures should be taken to improve the level of health behaviors of military cadres and promote the primary prevention of ICVD.%[目的]了解军队干部中缺血性心血管病(ICVD)高危人群健康行为的现状及影响因素.[方法]对当地某部35~59岁军队干部采用问卷调查ICVD相关因素,冠心病健康行为问卷采用健康促进生活方式量表II(HPLPⅡ)调查.[结果]977人中缺血性心血管病高危人员81人,占被调查人员的8.29%.ICVD高危人群组在健康行为总分(P=0.028)以及健康责任(P=0.002)、运动和锻炼(P=0.038)、营养(P=0.033)三个维度方面明显低于正常对照组.高危人群的一般人口学因素中,年龄(P=0.001)、婚姻状况(P=0.002)、工作类型(P=0.000)及家庭人均月收入(P=0.000)对健康行为有明显影响.[结论]军队干部ICVD高危人群的健康行为水平较低,应采取相应措施有针对性的提

  7. Cardiovascular health and cognitive function: the Maine-Syracuse Longitudinal Study.

    Directory of Open Access Journals (Sweden)

    Georgina E Crichton

    Full Text Available BACKGROUND: Smoking, physical inactivity, and poor diet, along with obesity, fasting glucose and blood pressure have been independently associated with poorer cognitive performance. Few studies have related scales representing a combination of these variables to multiple domains of cognitive performance. The aim of this study was to investigate the association between overall cardiovascular health, incorporating seven components, and cognitive function. METHODS: A cross-sectional analysis employing 972 participants, from the Maine-Syracuse Longitudinal Study was undertaken. Four health behaviors (body mass index, physical activity, diet, smoking and three health factors (total cholesterol, blood pressure, and fasting plasma glucose were measured. Each was categorized according to the American Heart Association definitions for ideal cardiovascular health, except diet, for which two food scores were calculated. A Cardiovascular Health Score was determined by summing the number of cardiovascular metrics at ideal levels. Cognitive function was assessed using a thorough neuropsychological test battery. RESULTS: Cardiovascular Health Score was positively associated with seven out of eight measures of cognitive function, with adjustment for age, education, and gender. With further adjustment for cardiovascular and psychological variables, these associations remained significant for Visual-Spatial Memory, Working Memory, Scanning and Tracking, Executive Function and the Global Composite score (p<0.05 for all. Ideal levels of a number of health factors and behaviors were positively associated with global cognitive performance. CONCLUSION: Increasing cardiovascular health, indexed by a higher number of metrics at ideal levels, is associated with greater cognitive performance. Smoking, physical activity, and diet are important components of cardiovascular health that impact upon cognition.

  8. Society for Cardiovascular Magnetic Resonance guidelines for reporting cardiovascular magnetic resonance examinations

    OpenAIRE

    van Rossum Albert C; Raman Subha V; McConnell Michael V; Lawson Mark A; Higgins Charles B; Friedrich Matthias G; Bogaert Jan G; Bluemke David; Hundley W Gregory; Flamm Scott; Kramer Christopher M; Nagel Eike; Neubauer Stefan

    2009-01-01

    Abstract These reporting guidelines are recommended by the Society for Cardiovascular Magnetic Resonance (SCMR) to provide a framework for healthcare delivery systems to disseminate cardiac and vascular imaging findings related to the performance of cardiovascular magnetic resonance (CMR) examinations.

  9. Functional Family Therapy: A Life Cycle Perspective.

    Science.gov (United States)

    Wetchler, Joseph L.

    1985-01-01

    Functional family therapy model assesses family behavior from perspectives of interactional process and functional payoffs for the individual family members. Illustrates that functional needs change as a result of development, and that by including a family life cycle perspective in the assessment process, clinicians will get a clearer picture of…

  10. Inflammation, Infection, and Future Cardiovascular Risk

    Science.gov (United States)

    2016-03-15

    Cardiovascular Diseases; Coronary Disease; Cerebrovascular Accident; Myocardial Infarction; Venous Thromboembolism; Heart Diseases; Infection; Chlamydia Infections; Cytomegalovirus Infections; Helicobacter Infections; Herpesviridae Infections; Inflammation

  11. [Future directions of cardiovascular surgery in China].

    Science.gov (United States)

    Hu, S S

    2016-08-01

    The cardiovascular surgery in China has achieved great progress both on scale and technology though development over the past thirty years. However, the technical predominance of cardiovascular surgery in therapies for some diseases has been weakened, along with developments of new drugs and interventional technology. Besides, the change of doctor-patient relationship result from internet medical information service and less attraction of cardiovascular surgery discipline to talents bring certain challenge to the development of cardiovascular surgery. Currently, cardiovascular surgeons should practice the "patient first" principle, carry out individual customized treatment and precision therapy, absorb the advantages of other subjects like intervention and imaging in order to achieve technological breakthroughs, create new treatment technologies and models with smaller trauma and better outcome, establish heart team to provide patient oriented treatment. Besides, cardiovascular surgeons should improve knowledge system by learning related technology and science, become hybrid doctors of research. Cardiovascular surgeons should pay high attention to critical effect of research on the disciplinary development, carry out question and demand oriented clinical studies, change the medical practice by virtue of research achievements, direct the treatment for cardiovascular diseases, and finally provide better health service and rebuild the predominance of cardiovascular surgery. PMID:27502127

  12. Biomechanical performance of new cardiovascular needles.

    Science.gov (United States)

    Thacker, J G; Ferguson, R E; Rodeheaver, G T; Edlich, R F

    2001-01-01

    Cardiovascular needles are now being manufactured from new stainless steel alloys containing high concentrations of nickel, Surgalloy and Ethalloy. The purpose of this study was to compare the biomechanical performance of a cardiovascular needle made of Surgalloy with a comparably sized needle made of Ethalloy. The parameters of biomechanical performance included sharpness, maintenance of sharpness, resistance to bending, and ductility. Because the biomechanical performance of these needles was remarkably similar, cardiovascular needles made of either the Surgalloy or Ethalloy alloys are recommended for cardiovascular surgery. PMID:11495105

  13. Cardiovascular risk profile: Cross-sectional analysis of motivational determinants, physical fitness and physical activity

    Directory of Open Access Journals (Sweden)

    Kiers Henri

    2010-10-01

    Full Text Available Abstract Background Cardiovascular risk factors are associated with physical fitness and, to a lesser extent, physical activity. Lifestyle interventions directed at enhancing physical fitness in order to decrease the risk of cardiovascular diseases should be extended. To enable the development of effective lifestyle interventions for people with cardiovascular risk factors, we investigated motivational, social-cognitive determinants derived from the Theory of Planned Behavior (TPB and other relevant social psychological theories, next to physical activity and physical fitness. Methods In the cross-sectional Utrecht Police Lifestyle Intervention Fitness and Training (UP-LIFT study, 1298 employees (aged 18 to 62 were asked to complete online questionnaires regarding social-cognitive variables and physical activity. Cardiovascular risk factors and physical fitness (peak VO2 were measured. Results For people with one or more cardiovascular risk factors (78.7% of the total population, social-cognitive variables accounted for 39% (p In addition to the prediction of intention to engage in physical activity and physical active behavior, we explored the impact of the intensity of physical activity. The intentsity of physical activity was only significantly related to physical active behavior (beta = .253, p 2 = .06, p 2 = .23, p For people with one or more cardiovascular risk factors, 39.9% had positive intentions to engage in physical activity and were also physically active, and 10.5% had a low intentions but were physically active. 37.7% had low intentions and were physically inactive, and about 11.9% had high intentions but were physically inactive. Conclusions This study contributes to our ability to optimize cardiovascular risk profiles by demonstrating an important association between physical fitness and social-cognitive variables. Physical fitness can be predicted by physical active behavior as well as by self-efficacy and the intensity of

  14. Internet-chatrooms : A new playground for bullies. A comparison of bullying behavior in school and in chatrooms from the perpetrators' perspective

    NARCIS (Netherlands)

    Katzer, Catarina; Fetchenhauer, Detlef; Belschak, Frank

    2009-01-01

    Bullying is not a specific phenomenon of the school environment. Different forms of verbal victimisation and social manipulation are also common behaviors in internet chatrooms. The present study compares traditional bullying with chatroom bullying. A total of 1,700 pupils of different secondary sch

  15. Reflection on the Studies of Environmental Behavior in China from a Sociological Perspective%社会学视角下中国环境行为研究的反思

    Institute of Scientific and Technical Information of China (English)

    陈昱昱

    2015-01-01

    目前中国社会学对环境行为的研究,在环境行为的概念上缺乏统一的认识,在方法上存在统计分析的西方化,在视角上缺少对所研究问题历史的关照。中国环境行为的社会学研究,既要在实证上也要在理论建构上体现中国学者的本土关怀。要实现这样的研究旨向,我们必须重新反思当下的研究,思索其“形而上之道”。本文对环境行为的概念作了社会学阐释,认为:在研究方法上要实现统计分析(宏观)和个案研究(微观)的沟通,并尝试扎根;在研究视角上要链接当下和历史;在研究价值的取向上要坚持价值中立。%In the current studies of environmental behavior from the perspective of Chinese sociology, there is no consistent recognition of the concept of environment behavior. As for the research methods, the statistical analy-sis is westernized;as for the research perspectives, there is a lack of the historical view. The sociological studies of Chinese environmental behavior should embody Chinese scholars’ concern of domestic issues from the empirical aspect and theoretical construction aspect as well. In order to achieve this goal, the present researches, especially the metaphysical“Tao”among them, should be reconsidered. Based on the sociological interpretation of“environ-mental behavior”, this article proposes that the future study should combine statistical analysis (macro level)with case study (micro level),link the present and history in a down-to-earth manner and insist value neutrality as far as the research value is concerned.

  16. Time Perspective and Physical Activity among Central Appalachian Adolescents

    Science.gov (United States)

    Gulley, Tauna

    2013-01-01

    Time perspective is a cultural behavioral concept that reflects individuals' orientations or attitudes toward the past, present, or future. Individuals' time perspectives influence their choices regarding daily activities. Time perspective is an important consideration when teaching adolescents about the importance of being physically…

  17. Radiation-induced cardiovascular effects

    Science.gov (United States)

    Tapio, Soile

    Recent epidemiological studies indicate that exposure to ionising radiation enhances the risk of cardiovascular mortality and morbidity in a moderate but significant manner. Our goal is to identify molecular mechanisms involved in the pathogenesis of radiation-induced cardiovascular disease using cellular and mouse models. Two radiation targets are studied in detail: the vascular endothelium that plays a pivotal role in the regulation of cardiac function, and the myocardium, in particular damage to the cardiac mitochondria. Ionising radiation causes immediate and persistent alterations in several biological pathways in the endothelium in a dose- and dose-rate dependent manner. High acute and cumulative doses result in rapid, non-transient remodelling of the endothelial cytoskeleton, as well as increased lipid peroxidation and protein oxidation of the heart tissue, independent of whether exposure is local or total body. Proteomic and functional changes are observed in lipid metabolism, glycolysis, mitochondrial function (respiration, ROS production etc.), oxidative stress, cellular adhesion, and cellular structure. The transcriptional regulators Akt and PPAR alpha seem to play a central role in the radiation-response of the endothelium and myocardium, respectively. We have recently started co-operation with GSI in Darmstadt to study the effect of heavy ions on the endothelium. Our research will facilitate the identification of biomarkers associated with adverse cardiac effects of ionising radiation and may lead to the development of countermeasures against radiation-induced cardiac damage.

  18. Marijuana Use and Cardiovascular Disease.

    Science.gov (United States)

    Franz, Christopher A; Frishman, William H

    2016-01-01

    Marijuana is currently the most used illicit substance in the world. With the current trend of decriminalization and legalization of marijuana in the US, physicians in the US will encounter more patients using marijuana recreationally over a diverse range of ages and health states. Therefore, it is relevant to review marijuana's effects on human cardiovascular physiology and disease. Compared with placebo, marijuana cigarettes cause increases in heart rate, supine systolic and diastolic blood pressures, and forearm blood flow via increased sympathetic nervous system activity. These actions increase myocardial oxygen demand to a degree that they can decrease the time to exercise-induced angina in patients with a history of stable angina. In addition, marijuana has been associated with triggering myocardial infarctions (MIs) in young male patients. Smoking marijuana has been shown to increase the risk of MI onset by a factor of 4.8 for the 60 minutes after marijuana consumption, and to increase the annual risk of MI in the daily cannabis user from 1.5% to 3% per year. Human and animal models suggest that this effect may be due to coronary arterial vasospasm. However, longitudinal studies have indicated that marijuana use may not have a significant effect on long-term mortality. While further research is required to definitively determine the impact of marijuana on cardiovascular disease, it is reasonable to recommend against recreational marijuana use, especially in individuals with a history of coronary artery disorders. PMID:26886465

  19. Enfermedad cardiovascular en Costa Rica

    Directory of Open Access Journals (Sweden)

    Lizzie M. Castillo S

    2006-07-01

    Full Text Available En Costa Rica la enfermedad cardiovascular cobra en promedio 6 vidas por día, lo cual representa un aumento escalonado en los últimos años, debido en su mayoría a cambios en el estilo de vida del costarricense. Además, llama la atención, que factores de riesgo para enfermedad cardiovascular como son el fumado, obesidad infantil, alcoholismo, diabetes, dislipidemia e hipertensión han mostrado un incremento en su incidencia. Por lo tanto,se pretende realizar una revisión de los programas de detección y de atención temprana a nivel institucional, en lo que respecta a la Caja Costarricense de Seguro Social como ente responsable de llevar a cabo los mismos. El adecuado conocimiento y uso de los programas pretende una disminución en la morbimortalidad de la misma,y su aplicación se hace obligatoria para el manejo de pacientes en atención primaria.

  20. Increased susceptibility to cardiovascular effects of dihydrocapcaicin in resuscitated rats. Cardiovascular effects of dihydrocapsaicin

    DEFF Research Database (Denmark)

    Fosgerau, Keld; Ristagno, Giuseppe; Jayatissa, Magdalena Niepsuj; Axelsen, Mads; Gotfredsen, Jacob W; Weber, Uno J; Køber, Lars; Torp-Pedersen, Christian; Videbaek, Charlotte

    2010-01-01

    Survivors of a cardiac arrest often have persistent cardiovascular derangements following cardiopulmonary resuscitation including decreased cardiac output, arrhythmias and morphological myocardial damage. These cardiovascular derangements may lead to an increased susceptibility towards the external...... and internal environment of the cardiovascular system as compared to the healthy situation....

  1. Mass media, secular trends, and the future of cardiovascular disease health promotion: an interpretive analysis.

    Science.gov (United States)

    Finnegan, J R; Viswanath, K; Hertog, J

    1999-12-01

    Mass media roles in promoting cardiovascular health in the context of lessons learned from major U.S. community studies, changing media technology, and emergent models of media-community partnerships are discussed. Three principal issues are explored: (1) implications of the current expansion, convergence, and harmonization of mass media technology;(2) recent trends in media coverage of heart disease and population practices; and (3) implications for the future relationship between the media and public health in cardiovascular health promotion. It is concluded that classic campaign models focusing on individual-level change have evolved to recognize environmental-level influences on behavior. Emergent public health campaign models have moved toward "agenda-building," in which the focus is on a more unified approach to influencing public and community agendas for social, behavioral, and policy change. Recent developments among the commercial mass media may offer new opportunities for public health partnerships to promote cardiovascular health. PMID:10641818

  2. Characteristics of physical attractiveness. Shape processing of dressed and naked realistic female bodies varying in WHR and observer perspective in heterosexual men and women: behavioral and electrophysiological experiments

    OpenAIRE

    Nussbaum, Sophie

    2011-01-01

    The WHR, reflecting the fat distribution, is a relevant measure of female physical attractiveness and an indicator of female health and reproductive capacity. Previous studies mainly investigated the divergence of WHR preferences between cultures and brain areas and body processing in relation with face processing, body motions or body expressions. However, no study has investigated the characteristics of physical attractiveness in heterosexual observers at behavioral and electrophysiological...

  3. The effects of non-suicidal self-injury on parenting behaviors: a longitudinal analyses of the perspective of the parent

    OpenAIRE

    Baetens, Imke; Claes, Laurence; Onghena, Patrick; Grietens, Hans; Van Leeuwen, Karla; Pieters, Ciska; Wiersema, Jan R.; Griffith, James W

    2015-01-01

    Background: The present study is the first to examine predictors and consequences of nonsuicidal self-injury (NSSI) in adolescence using parent-reported data in a longitudinal design. Across three time points, we examined the reciprocal effects of parent-reported parenting behaviors as they are related to adolescents' NSSI. Methods: The present study is a three-wave prospective study in a large sample of community adolescents and their parents. At time 1 (age 12), the sample consisted of...

  4. Intention to voluntary HIV counseling and testing (VCT) among health professionals in Jimma zone, Ethiopia: the theory of planned behavior (TPB) perspective

    OpenAIRE

    Abamecha, Fira; Godesso, Ameyu; Girma, Eshetu

    2013-01-01

    Background Voluntary HIV Counseling and Testing (VCT) forms one of the cornerstones of HIV prevention strategies. It is imperative to understand HIV testing correlates and their theoretical underpinnings in order to promote VCT uptake. The aim of this study was to predict the intention to VCT and associated factors among health professionals in Jimma zone, Ethiopia using the theory of planned behavior. Methods An institution based cross-sectional quantitative study among a sample of 336 healt...

  5. Exploring the Relationships Among Personal Values, Self-Concept´s Affective Security Dimension and Female Consumption Behavior: Perspectives from the Brazilian Retail Experience

    OpenAIRE

    Carlos Mello Moyano; Jorge Lengler

    2013-01-01

    Despite the importance of personal values and self-concept to understand consumers’ motivation and its influence over an individual’s action system, few studies have analyzed their relationship with consumer behavior in emerging countries. As a means of expression, consumers use brands and products in order to communicate their self-concept and personal values to their reference group. This study seeks to shed light on the causality relationship among personal values, self-concept´s affective...

  6. Discussion and proposal of use of qualitative tools of data collection for the analysis of violent behavior in the penitentiary environment from a multidisciplinary perspective

    OpenAIRE

    Meriem Khaled

    2011-01-01

    This Masterʼs Thesis addresses the tools definition to collect and analyze the relevant information to research in prisons, from a cross-sector point of view, aimed to prevent and predict violent behavior in prisonʼs environment. Taking as starting point several qualitative methods, we discuss the suitability of them and we propose using biographical narrative method as the proper one for capturing relevant information about prison organization, inmates and professionals working in that conte...

  7. Teacher's Moral Behavior and Teacher's Moral Development: On the Perspective of Organizational Citizenship Behavior%教师道德行为与道德成长:组织公民行为理论的视角

    Institute of Scientific and Technical Information of China (English)

    杨炎轩

    2012-01-01

    教师道德成长是教师道德行为的结果,要想促进教师道德成长,必须激发教师的道德行为。由于组织公民行为与道德行为在内涵与特征上具有很大的一致性,所以组织公民行为的诱导因素如变革型领导风格、组织支持和工作情境以及作用机制,可以看成是道德行为的激发因素及激励机制。鼓励创新、激活中层、团队合作作为变革型领导风格、组织支持和.Y-作情境作用机制实现的保障策略,具有直接和间接地促进教师道德成长的价值,也是教师道德成长的组织公民行为策略。%Teacher's moral development is the result of teacher's moral behavior. In order to promote teacher's moral development, it is necessary to stimulate teacher's moral behavior. There are great consistencies in connotation and characteristics between organizational citizenship behavior and moral behavior, so they share the same inducing factors, such as innovative leadership style, organizational support, and working environment, and effeeting mechanism. The major incentive strategies of organizational citizenship behavior, such as encouraging innovation, activating the middle, and team cooperation, directly or indirectly contribute to teacher's moral development, so they are also the strategies of promoting teacher's moral development.

  8. Exploring the Relationships Among Personal Values, Self-Concept´s Affective Security Dimension and Female Consumption Behavior: Perspectives from the Brazilian Retail Experience

    Directory of Open Access Journals (Sweden)

    Carlos Mello Moyano

    2013-10-01

    Full Text Available Despite the importance of personal values and self-concept to understand consumers’ motivation and its influence over an individual’s action system, few studies have analyzed their relationship with consumer behavior in emerging countries. As a means of expression, consumers use brands and products in order to communicate their self-concept and personal values to their reference group. This study seeks to shed light on the causality relationship among personal values, self-concept´s affective security dimension and female consumer behavior in retail environments in an emerging country, namely Brazil. To test the study’s hypotheses, confirmatory factor analysis and structural equation modeling were employed. The research sample consisted of 204 women who live in Brazil. The results reveal a significant relationship between personal values and women’s self-concept, especially on its affective security dimension. Self-concept also had significant influence on female consumers’ behavior. Seven of the eight hypotheses tested found support. Managerial implications of the findings are also discussed.

  9. The Role of Leadership and Peer Behaviors in the Performance and Well-Being of Women in Combat: Historical Perspectives, Unit Integration, and Family Issues.

    Science.gov (United States)

    Segal, Mady Wechsler; Smith, David G; Segal, David R; Canuso, Amy A

    2016-01-01

    This article analyzes how the behaviors of leaders and peers affect the performance and well-being of military women. Locating our analysis within the conceptual model in this issue, we summarize the empirical literature and make practice and policy recommendations. We synthesize results about unit integration, such as research on the conditions for successful integration of previously excluded groups and on the relationship between cohesion and performance. We apply lessons learned from the history of diversity integration in military and civilian organizations, analyzing the treatment of military personnel by race, gender, and sexual orientation. The opening of ground combat specialties and units to women is the latest step in personnel policy changes broadening the recruitment base. We analyze research on gender integration in contemporary armed forces, focusing on positive and negative effects on women of leader and peer behaviors. We discuss conditions for successfully integrating women and those that tend to lead to failure. We analyze military women's family issues, including the effects of deployments and how leaders and peers can help ameliorate problems-or exacerbate them with inappropriate or unsupportive behavior. PMID:26741899

  10. Do psychiatric disorders moderate the relationship between psychological distress and sexual risk-taking behaviors in young men who have sex with men? A longitudinal perspective.

    Science.gov (United States)

    Beidas, Rinad S; Birkett, Michelle; Newcomb, Michael E; Mustanski, Brian

    2012-06-01

    Young men who have sex with men (YMSM) account for two-thirds of new HIV infections in young people in the United States. Identifying between-person and within-person correlates of sexual risk-taking provides critical information for developing behavioral prevention efforts for this group. Possible predictors of sexual-risk behavior in YMSM include major depressive disorder (MDD), post-traumatic stress disorder (PTSD), and variation in psychological distress over time. To date, research has been equivocal with regard to the relationship between psychiatric disorders, psychological distress, and sexual risk behaviors. Participants included 119 16-20-year-old YMSM. Ethnicity/race of the participants included: black/African-American (46.2%), white (19.3%), Latino/Hispanic (12.6%), multiracial (11.8%), Asian/Pacific Islander (2.5%), and other (5.9%). Sexual risk outcomes included total number of male partners and unprotected anal sex acts across four waves of data collection (24 months). The study found that the between-person correlates, including ethnicity and age, predicted total male partners. Between-person correlates, including ethnicity, MDD, and a moderating effect of PTSD on psychological distress emerged as determinants of unprotected anal sex acts. PMID:22680282

  11. Association Between Leisure Time Physical Activity, Cardiopulmonary Fitness, Cardiovascular Risk Factors, and Cardiovascular Workload at Work in Firefighters

    OpenAIRE

    Clare C. W. Yu; Au, Chun T.; Lee, Frank Y.F.; So, Raymond C.H.; Wong, John P.S.; Mak, Gary Y.K.; Chien, Eric P.; Alison M. McManus

    2015-01-01

    Background Overweight, obesity, and cardiovascular disease risk factors are prevalent among firefighters in some developed countries. It is unclear whether physical activity and cardiopulmonary fitness reduce cardiovascular disease risk and the cardiovascular workload at work in firefighters. The present study investigated the relationship between leisure-time physical activity, cardiopulmonary fitness, cardiovascular disease risk factors, and cardiovascular workload at work in firefighters i...

  12. Factores de riesgo cardiovascular en estudiantes universitarios chilenos Cardiovascular risk factors in Chilean university students

    Directory of Open Access Journals (Sweden)

    María Teresa Chiang-Salgado

    1999-12-01

    cardiovasculares en la vida adulta de los jóvenes.OBJECTIVE: To study the prevalence of cardiovascular risk factors in asymptomatic university students of both sexes, aged 18 to 25 years. MATERIAL AND METHODS: Serum lipid levels were measured in a subsample of 293 subjects, using a Hitachi 717 chemical analyzer. Obesity was classified using Body Mass Index (BMI measurements. A self-applied questionnaire was used to collect data on sedentary life style, family history of cardiovascular disease and cigarette smoking. Statistical associations of lipid levels with lipidic and non-lipidic risk factors were assessed using Pearson´s chi² test and multiple regression. RESULTS: We found lipid risk levels in 29.2% for Total Cholesterol (CT, 16.2% for Low Density Lipoproteins (C-LDL and 5% for High Density Lipoproteins (C-HDL. The main non-lipidic factors were smoking (46.1% and sedentarism (60.8%. Obesity, hypertension and parental history of myocardial infarction were present in 1.9%, 4.6% and 11%, respectively. We observed an association of a lipid risk profile with obesity, cigarette smoking and family history. CONCLUSIONS: The results show that sedentarism and smoking are associated with a lipid risk profile. These results call for the need to develop appropriate behavior strategies for the successful prevention of cardiovascular disease.

  13. 14 CFR 67.111 - Cardiovascular.

    Science.gov (United States)

    2010-01-01

    ... STANDARDS AND CERTIFICATION First-Class Airman Medical Certificate § 67.111 Cardiovascular. Cardiovascular...; (b) A person applying for first-class medical certification must demonstrate an absence of myocardial...) An electrocardiogram will satisfy a requirement of paragraph (b) of this section if it is dated...

  14. Significance of Cardiac Rehabilitation on Cardiovascular Diseases

    OpenAIRE

    Krutika Gajjar; Dr.Parloop Bhatt; Dr.Yagnik S.Bhalodia; Dr.Sizan B.Patel; Chintan Patel

    2012-01-01

    Considering the high mortality and morbidity rate associated with cardiovascular diseases, Cardiacrehabilitation (CR) is regarded for prevention and management of cardiovascular diseases. CR servicesare generally provided in an outpatient as comprehensive, long-term programs involving medicalevaluation, prescribed exercise, cardiac risk factor modification, education and counseling. This includesnutritional therapies, weight loss program management of lipid abnormalities with diet and medicat...

  15. Cardiovascular Reactivity, Stress, and Physical Activity

    Directory of Open Access Journals (Sweden)

    Chun-Jung eHuang

    2013-11-01

    Full Text Available Psychological stress has been proposed as a major contributor to the progression of cardiovascular disease (CVD. Acute mental stress can activate the sympathetic-adrenal-medullary (SAM axis, eliciting the release of catecholamines (NE and EPI resulting in the elevation of heart rate (HR and blood pressure (BP. Combined stress (psychological and physical can exacerbate these cardiovascular responses, which may partially contribute to the elevated risk of CVD and increased proportionate mortality risks experienced by some occupations (e.g., firefighting and law enforcement. Studies have supported the benefits of physical activity on physiological and psychological health, including the cardiovascular response to acute stress. Aerobically trained individuals exhibit lower sympathetic nervous system (e.g., HR reactivity and enhanced cardiovascular efficiency (e.g., lower vascular reactivity and decreased recovery time in response to physical and/or psychological stress. In addition, resistance training has been demonstrated to attenuate cardiovascular responses and improve mental health. This review will examine stress-induced cardiovascular reactivity and plausible explanations for how exercise training and physical fitness (aerobic and resistance exercise can attenuate cardiovascular responses to stress. This enhanced functionality may facilitate a reduction in the incidence of stroke and myocardial infarction. Finally, this review will also address the interaction of obesity and physical activity on cardiovascular reactivity and CVD.

  16. Serum triglycerides and risk of cardiovascular disease.

    NARCIS (Netherlands)

    Boullart, I.; Graaf, J. de; Stalenhoef, A.F.H.

    2012-01-01

    Dyslipidemia, especially elevated serum levels of cholesterol, is causally related to cardiovascular disease. The specific role of triglycerides has long been controversial. In this article we discuss the role of serum triglycerides in relation to the risk of cardiovascular disease. First, the (path

  17. Cardiovascular death and manic-depressive psychosis

    DEFF Research Database (Denmark)

    Weeke, A; Juel, K; Vaeth, M

    2013-01-01

    In order to study if tricyclic antidepressant drugs (TCA) in therapeutic doses increase the risk of death due to cardiovascular causes, the relative mortality from cardiovascular diseases was studied in two large groups of first hospitalized manic-depressive patients, one from the TCA era, the ot...... disease, suicide, and other non-cancer causes....

  18. Subclinical organ damage and cardiovascular risk prediction

    DEFF Research Database (Denmark)

    Sehestedt, Thomas; Olsen, Michael H

    2010-01-01

    measuring subclinical organ damage. We have (i) reviewed recent studies linking markers of subclinical organ damage in the heart, blood vessels and kidney to cardiovascular risk; (ii) discussed the evidence for improvement in cardiovascular risk prediction using markers of subclinical organ damage; (iii...

  19. Genetic influences on cardiovascular stress reactivity

    NARCIS (Netherlands)

    Wu, Ting; Snieder, Harold; de Geus, Eco

    2010-01-01

    Individual differences in the cardiovascular response to stress play a central role in the reactivity hypothesis linking frequent exposure to psychosocial stress to adverse outcomes in cardiovascular health. To assess the importance of genetic factors, a meta-analysis was performed on all published

  20. 14 CFR 67.211 - Cardiovascular.

    Science.gov (United States)

    2010-01-01

    ... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Second-Class Airman Medical Certificate § 67.211 Cardiovascular. Cardiovascular standards for a second-class medical certificate are no established medical history or clinical diagnosis...