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Sample records for cardiorespiratory fitness skeletal

  1. Self-reported cardiorespiratory fitness

    DEFF Research Database (Denmark)

    Holtermann, Andreas; Marott, Jacob Louis; Gyntelberg, Finn;

    2015-01-01

    BACKGROUND: The predictive value and improved risk classification of self-reported cardiorespiratory fitness (SRCF), when added to traditional risk factors on cardiovascular disease (CVD) and longevity, are unknown. METHODS AND RESULTS: A total of 3843 males and 5093 females from the Copenhagen...

  2. The Obesity Paradox and Cardiorespiratory Fitness

    Directory of Open Access Journals (Sweden)

    Paul A. McAuley

    2012-01-01

    Full Text Available Cardiorespiratory fitness as an explanation for the obesity paradox warrants further examination. We evaluated independent and joint associations of cardiorespiratory fitness and adiposity with all-cause mortality in 811 middle-aged (age, 53.3±7.2 years male never smokers without documented cardiopulmonary disease or diabetes from the Veterans Exercise Testing Study (VETS. Cardiorespiratory fitness was quantified in metabolic equivalents (METs using final treadmill speed and grade achieved on a maximal exercise test. Subjects were grouped for analysis by METs: unfit (lowest third and fit (upper two-thirds; and by body mass index (kg/m2: nonobese (18.5−29.9 and obese (≥30.0. Associations of baseline fitness and adiposity measures with all-cause mortality were determined by Cox proportional hazards analysis adjusted for age, ethnicity, hypertension, hypercholesterolemia, family history of coronary artery disease, and cardiovascular medication use. In multivariate analysis, mortality risk for obese/fit men did not differ significantly from the nonobese/fit reference group. However, compared to the reference group, nonobese and obese unfit men were 2.2 (=0.01 and 1.9 (=0.03 times more likely to die, respectively. Cardiorespiratory fitness altered the obesity paradox such that mortality risk was lower for both obese and nonobese men who were fit.

  3. Cardiorespiratory fitness in individuals with intellectual disabilities-A review

    NARCIS (Netherlands)

    Oppewal, Alyt; Hilgenkamp, Thessa I. M.; van Wijck, Ruud; Evenhuis, Heleen M.

    2013-01-01

    Cardiorespiratory fitness is the ability of the circulatory, respiratory and muscular systems to supply oxygen during sustained physical activity. Low cardiorespiratory fitness levels have been found in individuals with intellectual disabilities (ID), which puts them at higher risk for cardiovascula

  4. Self-reported occupational physical activity and cardiorespiratory fitness

    DEFF Research Database (Denmark)

    Holtermann, Andreas; Marott, Jacob Louis; Gyntelberg, Finn;

    2016-01-01

    Objectives This study aimed to investigate whether workers with the combination of high occupational physical activity (OPA) and low cardiorespiratory fitness have an increased risk of cardiovascular disease (CVD) and all-cause mortality. Methods Using multivariable Cox proportional hazards...

  5. Cardiorespiratory Fitness and Cognitive Function in Midlife: Neuroprotection or Neuroselection?

    Science.gov (United States)

    Belsky, Daniel W.; Caspi, Avshalom; Israel, Salomon; Blumenthal, James A.; Poulton, Richie; Moffitt, Terrie E.

    2015-01-01

    Objective To determine if better cognitive functioning at midlife among more physically fit individuals reflects “neuroprotection,” in which fitness protects against age-related cognitive decline, or “neuroselection,” in which children with higher cognitive functioning select into more active lifestyles. Methods Children in the Dunedin Longitudinal Study (N=1,037) completed the Wechsler Intelligence Scales and the Trail-Making, Rey-Delayed-Recall, and Grooved-Pegboard tasks as children and again at midlife (age-38). Adult cardiorespiratory fitness was assessed using a submaximal exercise test to estimate maximum-oxygen-consumption-adjusted-for-body-weight in milliliters/minute/kilogram (VO2max). We tested if more-fit individuals had better cognitive functioning than their less-fit counterparts (which could be consistent with neuroprotection), and if better childhood cognitive functioning predisposed to better adult cardiorespiratory fitness (neuroselection). Finally, we examined possible mechanisms of neuroselection. Results Participants with better cardiorespiratory fitness had higher cognitive test scores at midlife. However, fitness-associated advantages in cognitive functioning were present already in childhood. After accounting for childhood-baseline performance on the same cognitive tests, there was no association between cardiorespiratory fitness and midlife cognitive functioning. Socioeconomic and health advantages in childhood, and healthier lifestyles during young adulthood explained most of the association between childhood cognitive functioning and adult cardiorespiratory fitness. Interpretation We found no evidence for a neuroprotective effect of cardiorespiratory fitness as of midlife. Instead, children with better cognitive functioning are selecting into healthier lives. Fitness interventions may enhance cognitive functioning. But, observational and experimental studies testing neuroprotective effects of physical fitness should consider

  6. Cardiorespiratory fitness, metabolic risk, and inflammation in children.

    Science.gov (United States)

    Christodoulos, Antonios D; Douda, Helen T; Tokmakidis, Savvas P

    2012-01-01

    The aim of this study was to investigate the independent associations among cardiorespiratory fitness, metabolic syndrome (MetS), and C-reactive protein (CRP) in children. The sample consisted of 112 children (11.4  ±  0.4 years). Data was obtained for children's anthropometry, cardiorespiratory fitness, MetS components, and CRP levels. MetS was defined using criteria analogous to the Adult Treatment Panel III definition. A MetS risk score was also computed. Prevalence of the MetS was 5.4%, without gender differences. Subjects with low fitness showed significantly higher MetS risk (P strategies aiming at reducing obesity and improving cardiorespiratory fitness in childhood might contribute to the prevention of the MetS in adulthood. PMID:22315623

  7. Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children

    Directory of Open Access Journals (Sweden)

    Antonios D. Christodoulos

    2012-01-01

    Full Text Available The aim of this study was to investigate the independent associations among cardiorespiratory fitness, metabolic syndrome (MetS, and C-reactive protein (CRP in children. The sample consisted of 112 children (11.4  ±  0.4 years. Data was obtained for children’s anthropometry, cardiorespiratory fitness, MetS components, and CRP levels. MetS was defined using criteria analogous to the Adult Treatment Panel III definition. A MetS risk score was also computed. Prevalence of the MetS was 5.4%, without gender differences. Subjects with low fitness showed significantly higher MetS risk (<0.001 and CRP (<0.007, compared to the high-fitness pupils. However, differences in MetS risk, and CRP between fitness groups decreased when adjusted for waist circumference. These data indicate that the mechanisms linking cardiorespiratory fitness, MetS risk and inflammation in children are extensively affected by obesity. Intervention strategies aiming at reducing obesity and improving cardiorespiratory fitness in childhood might contribute to the prevention of the MetS in adulthood.

  8. Relationships between cardiorespiratory fitness, metabolic control, and fat distribution in type 2 diabetes subjects.

    Science.gov (United States)

    Bacchi, Elisabetta; Negri, Carlo; Tarperi, Cantor; Baraldo, Anna; Faccioli, Niccolò; Milanese, Chiara; Zanolin, Maria Elisabetta; Lanza, Massimo; Cevese, Antonio; Bonora, Enzo; Schena, Federico; Moghetti, Paolo

    2014-01-01

    Factors contributing to the reduced cardiorespiratory fitness typical of sedentary subjects with type 2 diabetes are still largely unknown. In this study, we assessed the relationships between cardiorespiratory fitness and abdominal and skeletal muscle fat content in 39 untrained type 2 diabetes subjects, 27 males and 12 females (mean ± SD age 56.5 ± 7.3 year, BMI 29.4 ± 4.7 kg/m(2)). Peak oxygen uptake (VO2peak) and ventilatory threshold (VO2VT) were assessed by maximal cycle ergometer exercise test, insulin sensitivity by euglycemic-hyperinsulinemic clamp, and body composition by dual-energy X-ray absorptiometry. Magnetic resonance imaging was used to evaluate visceral, total subcutaneous (SAT), superficial (SSAT) and deep sub-depots of subcutaneous abdominal adipose tissue, and sagittal abdominal diameter (SAD), as well as femoral quadriceps skeletal muscle fat content. In univariate analysis, both VO2peak and VO2VT were inversely associated with BMI, total fat mass, SAT, SSAT, and sagittal abdominal diameter. VO2peak was also inversely associated with skeletal muscle fat content. A significant direct association was observed between VO2VT and insulin sensitivity. No associations between cardiorespiratory fitness parameters and metabolic profile data were found. In multivariable regression analysis, after adjusting for age and gender, VO2peak was independently predicted by higher HDL cholesterol, and lower SAD and skeletal muscle fat content (R (2) = 0.64, p < 0.001), whereas VO2VT was predicted only by sagittal abdominal diameter (R (2) = 0.48, p = 0.025). In conclusion, in untrained type 2 diabetes subjects, peak oxygen uptake is associated with sagittal abdominal diameter, skeletal muscle fat content, and HDL cholesterol levels. Future research should target these features in prospective intervention studies.

  9. The role of cardiorespiratory fitness on plasma lipid levels.

    Science.gov (United States)

    Parto, Parham; Lavie, Carl J; Swift, Damon; Sui, Xuemei

    2015-11-01

    Dyslipidemia is a treatable risk factor for cardiovascular disease. Epidemiological studies have demonstrated the importance of treatment for abnormalities in total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides. Aside from pharmacotherapy, exercise and cardio-respiratory fitness have been shown to have beneficial effects on decreasing cardiovascular disease risk. Even though previous data regarding the benefits of exercise on plasma lipids have been somewhat conflicting, numerous studies have demonstrated that exercise increases HDL-cholesterol and reduces the triglyceride levels. Also, smaller, more atherogenic LDL particles seem to decrease with increases in cardio-respiratory fitness and exercise, and favorable blood lipid profiles seem to persist longer through the adult life span. PMID:26436463

  10. Cardiorespiratory Fitness and Body Composition in Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Moreira Helena

    2014-12-01

    Full Text Available The object of the study was to analyze the relationship between aerobic fitness and body composition in postmenopausal women. We hypothesized that postmenopausal women that had higher adiposity had lower cardiorespiratory capacity, regardless of the characteristics of menopause. The sample included 208 women (57.57 ± 6.62 years, whose body composition and the basal metabolic rate were evaluated by octopolar bioimpedance (InBody 720 and the oxygen uptake by the modified Bruce protocol. Most of the sample showed obesity and a high visceral fat area. The visceral fat area and the basal metabolic rate explained 30% of the variation of oxygen uptake, regardless of age, time, nature or hormone therapy. The values of the latter variables were reduced in the presence of high central adiposity (-6.16 ml/kg/min and the basal metabolic rate of less than 1238 kcal/day (-0.18 ml/kg/min. The women with oxygen uptake above 30.94 ml/kg/min showed lower values of total and central adiposity when compared with other groups. With an increase of aerobic fitness, there was a growing tendency of the average values of the soft lean mass index, with differences between the groups low-high and moderate-high. These results suggest worsening of the cardiorespiratory condition with an increase of central adiposity and a decrease of the BMR, regardless of age and menopause characteristics.

  11. Contribution of cardiorespiratory fitness to the obesity paradox.

    Science.gov (United States)

    McAuley, Paul A; Beavers, Kristen M

    2014-01-01

    Until recently, cardiorespiratory fitness (CRF) has been overlooked as a potential modifier of the inverse association between obesity and mortality (the so-called obesity paradox), observed in patients with known or suspected cardiovascular (CV) disease. Evidence from five observational cohort studies of 30,104 patients (87% male) with CV disease indicates that CRF significantly alters the obesity paradox. There is general agreement across studies that the obesity paradox persists among patients with low CRF, regardless of whether adiposity is assessed by body mass index, waist circumference, or percentage body fat. However, among patients with high CRF, risk of all-cause mortality is lowest for the overweight category in some, but not all, studies, suggesting that higher levels of fitness may modify the relationship between body fatness and survival in patients manifesting an obesity paradox. Further study is needed to better characterize the joint contribution of CRF and obesity on mortality in diverse populations.

  12. Cardiorespiratory fitness and white matter integrity in Alzheimer's disease.

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    Perea, R D; Vidoni, E D; Morris, J K; Graves, R S; Burns, J M; Honea, R A

    2016-09-01

    The objective of this study was to investigate the relationship between cardiorespiratory (CR) fitness and the brain's white matter tract integrity using diffusion tensor imaging (DTI) in the Alzheimer's disease (AD) population. We recruited older adults in the early stages of AD (n = 37; CDR = 0.5 and 1) and collected cross-sectional fitness and diffusion imaging data. We examined the association between CR fitness (peak oxygen consumption [VO2peak]) and fractional anisotropy (FA) in AD-related white matter tracts using two processing methodologies: a tract-of-interest approach and tract-based spatial statistic (TBSS). Subsequent diffusivity metrics (radial diffusivity [RD], mean diffusivity [MD], and axial diffusivity [A × D]) were also correlated with VO2peak. The tract-of-interest approach showed that higher VO2peak was associated with preserved white matter integrity as measured by increased FA in the right inferior fronto-occipital fasciculus (p = 0.035, r = 0.36). We did not find a significant correlation using TBSS, though there was a trend for a positive association between white matter integrity and higher VO2peak measures (p fitness levels in early AD participants may be related to preserved white matter integrity. However to draw stronger conclusions, further study on the relationship between fitness and white matter deterioration in AD is necessary. PMID:26239997

  13. Physical inactivity, neurological disability, and cardiorespiratory fitness in multiple sclerosis

    Science.gov (United States)

    Motl, R. W.; Goldman, M.

    2011-01-01

    Objective We examined the associations among physical activity, neurological disability, and cardiorespiratory fitness in two studies of individuals with multiple sclerosis (MS). Method Study 1 included 25 women with relapsing-remitting MS (RRMS) who undertook an incremental exercise test for measuring peak oxygen (V̇O2peak) consumption, wore an accelerometer during a 7-day period, and completed the Godin Leisure-Time Exercise Questionnaire (GLTEQ). Study 2 was a follow-up of Study 1 and included 24 women with RRMS who completed the self-reported Expanded Disability Status Scale (EDSS), undertook an incremental exercise test, wore an accelerometer during a 7-day period, and completed the GLTEQ. Results Study 1 indicated that V̇O2peak was significantly correlated with accelerometer counts (pr = 0.69) and GLTEQ scores (pr = 0.63) even after controlling for age and MS duration. Study 2 indicated that V̇O2peak was significantly correlated with accelerometer counts (pr = 0.50), GLTEQ scores (pr = 0.59), and EDSS scores (pr = −0.43) even after controlling for age and MS duration; there was a moderate partial correlation between accelerometer counts and EDSS scores (pr = −0.43). Multiple linear regression analysis indicated that both accelerometer counts (β = 0.32) and EDSS scores (β = −0.40) had statistically significant associations with V̇O2peak. Conclusion The findings indicate that physical inactivity and neurological disability might represent independent risk factors for reduced levels of cardiorespiratory fitness in this population. PMID:21108624

  14. A review of cardiorespiratory fitness-related neuroplasticity in the aging brain

    Directory of Open Access Journals (Sweden)

    Scott M Hayes

    2013-07-01

    Full Text Available The literature examining the relationship between cardiorespiratory fitness and the brain in older adults has increased rapidly, with 30 of 34 studies published since 2008. Here we review cross-sectional and exercise intervention studies in older adults examining the relationship between cardiorespiratory fitness and brain structure and function, typically assessed using Magnetic Resonance Imaging (MRI. Studies of patients with Alzheimer’s disease are discussed when available. The structural MRI studies revealed a consistent positive relationship between cardiorespiratory fitness and brain volume in cortical regions including anterior cingulate, lateral prefrontal, and lateral parietal cortex. Support for a positive relationship between cardiorespiratory fitness and medial temporal lobe volume was less consistent, although evident when a region-of-interest approach was implemented. In fMRI studies, cardiorespiratory fitness in older adults was associated with activation in similar regions as those identified in the structural studies, including anterior cingulate, lateral prefrontal, and lateral parietal cortex, despite heterogeneity among the functional tasks implemented. This comprehensive review highlights the overlap in brain regions showing a positive relationship with cardiorespiratory fitness in both structural and functional imaging modalities. The findings suggest that aerobic exercise and cardiorespiratory fitness contribute to healthy brain aging, although additional studies in Alzheimer’s disease are needed.

  15. Cardiorespiratory fitness and its association with thalamic, hippocampal, and basal ganglia volumes in multiple sclerosis

    OpenAIRE

    Motl, Robert W.; Pilutti, Lara A.; Hubbard, Elizabeth A.; Wetter, Nathan C.; Sosnoff, Jacob J.; Sutton, Bradley P.

    2015-01-01

    Background: There is little known about cardiorespiratory fitness and its association with volumes of the thalamus, hippocampus, and basal ganglia in multiple sclerosis (MS). Such inquiry is important for identifying a possible behavioral approach (e.g., aerobic exercise training) that might change volumes of deep gray matter (DGM) structures associated with cognitive and motor functions in MS. Purpose: This study examined the association between cardiorespiratory fitness and volumes of th...

  16. Cardiorespiratory Fitness Attenuates the Influence of Amyloid on Cognition.

    Science.gov (United States)

    Schultz, Stephanie A; Boots, Elizabeth A; Almeida, Rodrigo P; Oh, Jennifer M; Einerson, Jean; Korcarz, Claudia E; Edwards, Dorothy F; Koscik, Rebecca L; Dowling, Maritza N; Gallagher, Catherine L; Bendlin, Barbara B; Christian, Bradley T; Zetterberg, Henrik; Blennow, Kaj; Carlsson, Cynthia M; Asthana, Sanjay; Hermann, Bruce P; Sager, Mark A; Johnson, Sterling C; Stein, James H; Okonkwo, Ozioma C

    2015-11-01

    The aim of this study was to examine cross-sectionally whether higher cardiorespiratory fitness (CRF) might favorably modify amyloid-β (Aβ)-related decrements in cognition in a cohort of late-middle-aged adults at risk for Alzheimer's disease (AD). Sixty-nine enrollees in the Wisconsin Registry for Alzheimer's Prevention participated in this study. They completed a comprehensive neuropsychological exam, underwent 11C Pittsburgh Compound B (PiB)-PET imaging, and performed a graded treadmill exercise test to volitional exhaustion. Peak oxygen consumption (VO2peak) during the exercise test was used as the index of CRF. Forty-five participants also underwent lumbar puncture for collection of cerebrospinal fluid (CSF) samples, from which Aβ42 was immunoassayed. Covariate-adjusted regression analyses were used to test whether the association between Aβ and cognition was modified by CRF. There were significant VO2peak*PiB-PET interactions for Immediate Memory (p=.041) and Verbal Learning & Memory (p=.025). There were also significant VO2peak*CSF Aβ42 interactions for Immediate Memory (p<.001) and Verbal Learning & Memory (p<.001). Specifically, in the context of high Aβ burden, that is, increased PiB-PET binding or reduced CSF Aβ42, individuals with higher CRF exhibited significantly better cognition compared with individuals with lower CRF. In a late-middle-aged, at-risk cohort, higher CRF is associated with a diminution of Aβ-related effects on cognition. These findings suggest that exercise might play an important role in the prevention of AD.

  17. Graded associations between cardiorespiratory fitness, fatness, and blood pressure in children and adolescents

    DEFF Research Database (Denmark)

    Klasson-Heggebø, L.; Andersen, Lars Bo; Wennlöf, A.H.;

    2006-01-01

    Objective: To measure the graded relation between cardiorespiratory fitness and sum of skinfolds, waist circumference, and blood pressure in children and adolescents participating in the European youth heart study. Methods: The participants were 4072 children and adolescents (aged 9 and 15) from...... Denmark, Portugal, Estonia, and Norway. Cardiorespiratory fitness was indirectly determined using a maximal ergometer cycle test. The sum of four skinfolds, waist circumference, and blood pressure were assessed with a standardised protocol. Linear regression analysis was used to test the graded relation.......09-0.26 for the different sexes and age groups). Systolic and diastolic blood pressure also showed a curvilinear relation with cardiorespiratory fitness, and fitness explained 2% of the variance in systolic blood pressure. The difference in systolic blood pressure between the least and most fit was 6 mm Hg...

  18. Physical Activity, Body Mass Index, and Cardiorespiratory Fitness among School Children in Taiwan: A Cross-Sectional Study

    OpenAIRE

    Pei-Lin Hsieh; Min-Li Chen; Chiu-Mieh Huang; Wen-Chyuan Chen; Chun-Huei Li; Li-Chun Chang

    2014-01-01

    There is evidence that cardiorespiratory fitness and physical activity significantly reduce cardiovascular risks in adults. A better understanding of the association between cardiorespiratory fitness, physical activity, and childhood obesity is vital in assessing the benefits of interventions to prevent obesity. This study was to examine the relationship between physical activity, body mass index, and cardiorespiratory fitness levels in Taiwanese children. A cross-sectional study was designed...

  19. Changes in cardiorespiratory fitness among children and adolescents in Australia: 1997 and 2004.

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    Okely, Anthony D; Hardy, Louise L; Booth, Michael L; Dobbins, Timothy A; Denney-Wilson, Elizabeth A; Yang, Baohui

    2010-06-01

    In this paper, we describe changes in cardiorespiratory fitness among children and adolescents in New South Wales, Australia from 1997 to 2004. Altogether, 4363 children and adolescents were surveyed in 1997 and 3720 were surveyed in 2004. Participants were randomly selected from Grades 4 and 6 in primary school and Grades 8 and 10 in high schools. Cardiorespiratory fitness was assessed on both occasions using the 20-m shuttle run test. There was a very small, but statistically significant, increase in the median number of laps completed for primary (P = 0.02) and high school girls (P = 0.02) and high school boys (P = 0.01); however, the prevalence of adequate cardiorespiratory fitness did not change significantly from 1997 to 2004 for primary or high school boys or girls. Cardiorespiratory fitness was higher among the most socially advantaged boys and girls and this tertile also recorded the greatest increases in all but one group. Over the period 1997 to 2004, the prevalence of adequate cardiorespiratory fitness among students rose slightly in general. It is concerning that the gap between low and high socio-economic tertiles appears to have widened. PMID:20480429

  20. Cross-Sectional Associations of Objectively Measured Physical Activity, Cardiorespiratory Fitness and Anthropometry in European Adults

    NARCIS (Netherlands)

    Wientzek, A.; Diaz, M.J.T.; Castano, J.M.H.; Amiano, P.; Arriola, L.; Overvad, K.; Ostergaard, J.N.; Charles, M.A.; Fagherazzi, G.; Palli, D.; Bendinelli, B.; Skeie, G.; Borch, K.B.; Wendel-Vos, W.; Hollander, de E.L.; May, A.M.; Ouden, den M.E.M.; Trichopoulou, A.; Valanou, E.; Soderberg, S.; Franks, P.W.; Brage, S.; Vigl, M.; Boeing, H.; Ekelund, U.

    2014-01-01

    Objective: To quantify the independent associations between objectively measured physical activity (PA), cardiorespiratory fitness (CRF), and anthropometry in European men and women. Methods: 2,056 volunteers from 12 centers across Europe were fitted with a heart rate and movement sensor at 2 visits

  1. Cardiorespiratory Fitness and the Flexible Modulation of Cognitive Control in Preadolescent Children

    Science.gov (United States)

    Pontifex, Matthew B.; Raine, Lauren B.; Johnson, Christopher R.; Chaddock, Laura; Voss, Michelle W.; Cohen, Neal J.; Kramer, Arthur F.; Hillman, Charles H.

    2011-01-01

    The influence of cardiorespiratory fitness on the modulation of cognitive control was assessed in preadolescent children separated into higher- and lower-fit groups. Participants completed compatible and incompatible stimulus-response conditions of a modified flanker task, consisting of congruent and incongruent arrays, while ERPs and task…

  2. Psychosocial Variables Associated with Body Composition and Cardiorespiratory Fitness in Middle School Students

    Science.gov (United States)

    Greenleaf, Christy A.; Petrie, Trent A.; Martin, Scott B.

    2010-01-01

    This study examined the associations among self-esteem, depression, physical self-concept, and body satisfaction among 1,022 middle school students who were in the FITNESSGRAM[R] Healthy Fitness Zone[TM] (HFZ) compared to those in the Needs Improvement Zone (NIZ) for body composition and cardiorespiratory fitness. After controlling for…

  3. A 24-h assessment of physical activity and cardio-respiratory fitness among female hospital cleaners

    DEFF Research Database (Denmark)

    Larsen, Mette Korshøj; Krustrup, Peter; Jespersen, Tobias;

    2013-01-01

    The aim of this study was to evaluate the feasibility of methods for objective 24-h sampling of physical activity among cleaners. Twenty cleaners participated in three 24-h measurements. Amount of steps, heart rate (HR), cardio-respiratory fitness, body mass index (BMI) and blood pressure were...... measured. The methods were feasible for the objective 24-h sampling of physical activity and cardio-respiratory fitness among cleaners. Measurements showed that the cleaners walked 20,198 ± 4,627 steps per day. During working hours, the average cardio-respiratory load was 25 ± 6% of heart rate reserve (HRR......). The cleaners had a low estimated cardio-respiratory fitness (34 mlO2/kg/min), a high BMI (50%, >25 kg/m(2)) and blood pressure (50%, >120/>80 mmHg). The high amount of steps, the relatively high cardiovascular load at work and low cardio-respiratory fitness illustrate the need for further investigation...

  4. Cardiorespiratory Fitness in Women with and without Lymphedema following Breast Cancer Treatment

    OpenAIRE

    2012-01-01

    Following breast cancer (BC) treatment, many women develop impairments that may impact cardiorespiratory (CR) fitness. The aims of this study were to 1) evaluate CR fitness in women following BC treatment, 2) evaluate differences in CR fitness in those with and without breast cancer-related lymphedema (BCRL) and compare these to age-matched norms, and 3) evaluate the contribution of predictor variables to CR fitness. 136 women post-BC treatment completed testing: 67 with BCRL, and 69 without....

  5. Sedentary time and vigorous physical activity are independently associated with cardiorespiratory fitness in middle school youth.

    Science.gov (United States)

    Moore, Justin B; Beets, Michael W; Barr-Anderson, Daheia J; Evenson, Kelly R

    2013-01-01

    The purpose of this cross-sectional study was to examine the relationship between objectively measured physical activity, sedentary time, and cardiorespiratory fitness in a diverse sample of youth. Participants were recruited from three middle schools and completed assessments of height, weight, cardiorespiratory fitness, and wore an accelerometer for a minimum of four days. Hierarchical general linear models controlling for age, body mass index (BMI) percentile, and sex were used to evaluate the association of time (minutes per day) spent sedentary, and in moderate physical activity and vigorous physical activity with cardiorespiratory fitness (i.e., heart rate response [beats per minute], dependent variable). Results indicated age (β = -0.16, P 0.05) and vigorous (β = -0.22, P engaging in vigorous activity.

  6. The association between physical activity, cardiorespiratory fitness and self-rated health

    DEFF Research Database (Denmark)

    Eriksen, Louise; Curtis, Tine; Grønbæk, Morten;

    2013-01-01

    OBJECTIVE: To investigate the joint association between self-reported physical activity as well as cardiorespiratory fitness and self-rated health among healthy women and men. METHOD: Data from 10,416 participants in The Danish Health Examination Survey 2007-2008 which took part in 13 Danish...... municipalities were analyzed. Leisure time physical activity level and self-rated health were based on self-reported questionnaire data. Optimal self-rated health was defined as "very good" or "good" self-rated health. Cardiorespiratory fitness (mL O2·min(-1)·kg(-1)) was estimated from maximal power output...... in a maximal cycle exercise test. RESULTS: A strong dose-response relation between cardiorespiratory fitness and self-rated health as well as between physical activity level and self-rated health among both women and men was found. Within categories of physical activity, odds ratios for optimal self...

  7. The sexual dimorphic association of cardiorespiratory fitness to working memory in children.

    Science.gov (United States)

    Drollette, Eric S; Scudder, Mark R; Raine, Lauren B; Davis Moore, R; Pontifex, Matthew B; Erickson, Kirk I; Hillman, Charles H

    2016-01-01

    The present investigation examined the sexual dimorphic patterns of cardiorespiratory fitness to working memory in preadolescent children (age range: 7.7-10.9). Data were collected in three separate studies (Study 1: n = 97, 42 females; Study 2: n = 95, 45 females; Study 3: n = 84, 37 females). All participants completed a cardiorespiratory fitness assessment in addition to a specific measure of working memory (i.e. the operation span task, the n-back task, or the Sternberg task). Results from all three samples revealed that higher cardiorespiratory fitness levels were associated with better working memory performance only for males with no such relation observed for females. In addition, the sexually dimorphic pattern was selective for the most challenging working memory conditions in each task. Together, these findings reveal new evidence that cardiorespiratory fitness is selectively related to better working memory performance for male children. This investigation provides additional insight into how interventions aimed at improving fitness may influence cognitive development differentially among preadolescent children. PMID:25702796

  8. Status of police officers with regard to selected cardio-respiratory and body compositional fitness variables.

    Science.gov (United States)

    Stamford, B A; Weltman, A; Moffatt, R J; Fulco, C

    1978-01-01

    Physical performance and body composition characteristics of members (n = 75) and recruits (n = 61) of the Louisville Police Department (total n = 136) were assessed. Members were randomly selected males and ranged in age from 20 to 55 years and were ranked from the newest inductee through and including the Chief of Police. Members between the ages of 20 and 29 years assigned to active duty possessed average cardio-respiratory fitness (Vo2max). With age, cardio-respiratory fitness decreased and body weight and body fatness progressively increased. Male and female recruits entering basic training also demonstrated average cardio-respiratory fitness. Significant (P less than .05) increases for males and females in Vo2max and decreases in body fatness (males) were found following 4 months of physically rigorous recruit training. Fifteen of the male recruits who completed training were retested following 1 year of active duty. During active duty, physical activity involvement was limited to job requirements with no additional physical training imposed. Cardio-respiratory fitness and body fatness reverted to pre-training levels. It was concluded that the physical demands associated with police work are too low to permit maintenance of physical fitness.

  9. Adverse effect of outdoor air pollution on cardiorespiratory fitness in Chinese children

    Science.gov (United States)

    Gao, Yang; Chan, Emily Y. Y.; Zhu, Yingjia; Wong, Tze Wai

    2013-01-01

    Little is known about the health impact of air pollution on children's cardiovascular health. A cross-sectional study was conducted and data was analysed in 2048 Chinese schoolchildren (aged 8-10 years) in three districts of Hong Kong to examine the association between exposure to outdoor air pollution and cardiorespiratory fitness. Annual means of ambient PM10, SO2, NO2 and O3 from 1996 to 2003 were used to estimate individual exposure of the subjects. Cardiorespiratory fitness was measured for maximal oxygen uptake (VO2max), predicted by the multistage fitness test (MFT). Height and weight were measured and other potential confounders were collected with questionnaires. Analysis of covariance was performed to estimate the impact of air pollution on complete speed in the MFT and predicted VO2max. The results showed that children in high-pollution district had significantly lower complete speed and predicted VO2max compared to those in low- and moderate-pollution districts. Complete speed and predicted VO2max was estimated to reduce 0.327 km h-1 and 1.53 ml kg-1 min-1 per 10 μg m-3 increase in PM10 annual mean respectively, with those in girls being greater than in boys. Being physically active could not significantly result in improved cardiorespiratory fitness in polluted districts. The adverse effect seems to be independent of short-term exposure to air pollution. We concluded that long-term exposure to higher outdoor air pollution levels was negatively associated with cardiorespiratory fitness in Chinese schoolchildren, especially for girls. PM10 is the most relevant pollutant of the adverse effect. Elevated cardiorespiratory fitness observed in physically activate children could be negated by increased amount of inhaled pollutants during exercise.

  10. Metabolic, cardiorespiratory, and neuromuscular fitness performance in children with cerebral palsy: A comparison with healthy youth

    Science.gov (United States)

    García, Claudia Cardona; Alcocer-Gamboa, Alberto; Ruiz, Margarita Pérez; Caballero, Ignacio Martínez; Faigenbaum, Avery D.; Esteve-Lanao, Jonathan; Saiz, Beatriz Moral; Lorenzo, Teresa Martín; Lara, Sergio Lerma

    2016-01-01

    The aim of this study was to assess metabolic, cardiorespiratory, and neuromuscular fitness parameters in children with spastic cerebral palsy (CP) and to compare these findings with typically developing children. 40 children with CP (21 males, 19 females; mean age, 11.0±3.3 yr; range, 6.5–17.1 yr; Gross Motor Function Classification System levels 1 or 2) and 40 healthy, age- and sex-matched children completed a test battery that consisted of 8 tests and 28 measures that assessed cardio-respiratory fitness, energy expenditure, anaerobic endurance, muscle strength, agility, stability and flexibility. Children with CP had significantly lower performance (P<0.05) on most cardiorespiratory and metabolic tests than those of healthy children, Differences in neuromuscular measures of muscular strength, speed, agility, anaerobic endurance, and flexibility between groups were most apparent. Grouped differences in cardiorespiratory variables revealed a 25% difference in performance, whereas grouped differences in metabolic and neuromuscular measures were 43% and 60%, respectively. The physical fitness of contemporary children with CP is significantly less than healthy, age-matched children. Significant differences in neuromuscular measures between groups can aid in the identification of specific fitness abilities in need of improvement in this population. PMID:27162775

  11. Cardiorespiratory fitness and its association with thalamic, hippocampal, and basal ganglia volumes in multiple sclerosis

    Science.gov (United States)

    Motl, Robert W.; Pilutti, Lara A.; Hubbard, Elizabeth A.; Wetter, Nathan C.; Sosnoff, Jacob J.; Sutton, Bradley P.

    2015-01-01

    Background There is little known about cardiorespiratory fitness and its association with volumes of the thalamus, hippocampus, and basal ganglia in multiple sclerosis (MS). Such inquiry is important for identifying a possible behavioral approach (e.g., aerobic exercise training) that might change volumes of deep gray matter (DGM) structures associated with cognitive and motor functions in MS. Purpose This study examined the association between cardiorespiratory fitness and volumes of the thalamus, hippocampus, and basal ganglia in MS. Method We enrolled 35 persons with MS who underwent a maximal exercise test for measuring cardiorespiratory fitness as peak oxygen consumption (VO2peak) and brain MRI. Volumes of the thalamus, hippocampus, caudate, putamen, and pallidum were calculated from 3D T1-weighted structural brain images. We examined associations using partial (pr) correlations controlling for demographic and clinical variables. Results VO2peak was significantly associated with composite scaled volumes of the caudate(pr = .47, p < .01), putamen (pr = .44, p < .05), pallidum (pr = .40, p < .05), and hippocampus (pr = .42, p < .05), but not thalamus (pr = .31, p = .09), when controlling for sex, age, disability, and duration of MS. Conclusion Our results provide novel evidence that cardiorespiratory fitness is associated with volumes of DGM structures that are involved in motor and cognitive functions in MS. PMID:25844320

  12. The Sexual Dimorphic Association of Cardiorespiratory Fitness to Working Memory in Children

    Science.gov (United States)

    Drollette, Eric S.; Scudder, Mark R.; Raine, Lauren B.; Davis Moore, R.; Pontifex, Matthew B.; Erickson, Kirk I.; Hillman, Charles H.

    2016-01-01

    The present investigation examined the sexual dimorphic patterns of cardiorespiratory fitness to working memory in preadolescent children (age range: 7.7-10.9). Data were collected in three separate studies (Study 1: n = 97, 42 females; Study 2: n = 95, 45 females; Study 3: n = 84, 37 females). All participants completed a cardiorespiratory…

  13. Does cardiorespiratory fitness modify the association between birth weight and insulin resistance in adult life?

    Directory of Open Access Journals (Sweden)

    Tomoko Aoyama

    Full Text Available OBJECTIVE: Lower birth weight is associated with higher insulin resistance in later life. The aim of this study was to determine whether cardiorespiratory fitness modifies the association of birth weight with insulin resistance in adults. METHODS: The subjects were 379 Japanese individuals (137 males, 242 females aged 20-64 years born after 1943. Insulin resistance was assessed using a homeostasis model assessment of insulin resistance (HOMA-IR, which is calculated from fasting blood glucose and insulin levels. Cardiorespiratory fitness (maximal oxygen uptake, VO2max was assessed by a maximal graded exercise test on a cycle ergometer. Birth weight was reported according to the Maternal and Child Health Handbook records or the subject's or his/her mother's memory. RESULTS: The multiple linear regression analysis revealed that birth weight was inversely associated with HOMA-IR (β = -0.141, p = 0.003, even after adjustment for gender, age, current body mass index, mean blood pressure, triglycerides, HDL cholesterol, and smoking status. Further adjustments for VO2max made little difference in the relationship between birth weight and HOMA-IR (β = -0.148, p = 0.001, although VO2max (β = -0.376, p<0.001 was a stronger predictor of HOMA-IR than birth weight. CONCLUSIONS: The results showed that the association of lower birth weight with higher insulin resistance was little modified by cardiorespiratory fitness in adult life. However, cardiorespiratory fitness was found to be a stronger predictor of insulin resistance than was birth weight, suggesting that increasing cardiorespiratory fitness may have a much more important role in preventing insulin resistance than an individual's low birth weight.

  14. Independent associations of physical activity and cardiorespiratory fitness with metabolic risk factors in children: the European youth heart study

    DEFF Research Database (Denmark)

    Ekelund, U; Anderssen, S A; Froberg, K;

    2007-01-01

    AIMS/HYPOTHESIS: High levels of cardiorespiratory fitness (CRF) and physical activity (PA) are associated with a favourable metabolic risk profile. However, there has been no thorough exploration of the independent contributions of cardiorespiratory fitness and subcomponents of activity (total PA...... the association between activity and clustered risk is independent of adiposity. Our results suggest that fitness and activity affect metabolic risk through different pathways....

  15. Combined Impact of Cardiorespiratory Fitness and Visceral Adiposity on Metabolic Syndrome in Overweight and Obese Adults in Korea

    OpenAIRE

    Sue Kim; Ji-Young Kim; Duk-Chul Lee; Hye-Sun Lee; Ji-Won Lee; Jeon, Justin Y

    2014-01-01

    BACKGROUND: Obesity, especially visceral obesity, is known to be an important correlate for cardiovascular disease and increased mortality. On the other hand, high cardiorespiratory fitness is suggested to be an effective contributor for reducing this risk. This study was conducted to determine the combined impact of cardiorespiratory fitness and visceral adiposity, otherwise known as fitness and fatness, on metabolic syndrome in overweight and obese adults. METHODS: A total of 232 overweight...

  16. Cardiorespiratory Fitness and Cognitive Function in Midlife: Neuroprotection or Neuroselection?

    OpenAIRE

    Belsky, Daniel W.; Caspi, Avshalom; Israel, Salomon; Blumenthal, James A.; Poulton, Richie; Moffitt, Terrie E.

    2015-01-01

    Objective—To determine if better cognitive functioning at midlife among more physically fit individuals reflects “neuroprotection,” in which fitness protects against age-related cognitive decline, or “neuroselection,” in which children with higher cognitive functioning select into more active lifestyles.Methods—Children in the Dunedin Longitudinal Study (N=1,037) completed the Wechsler Intelligence Scales and the Trail-Making, Rey-Delayed-Recall, and Grooved-Pegboard tasks as children and aga...

  17. Metabolic, cardiorespiratory, and neuromuscular fitness performance in children with cerebral palsy: A comparison with healthy youth.

    Science.gov (United States)

    García, Claudia Cardona; Alcocer-Gamboa, Alberto; Ruiz, Margarita Pérez; Caballero, Ignacio Martínez; Faigenbaum, Avery D; Esteve-Lanao, Jonathan; Saiz, Beatriz Moral; Lorenzo, Teresa Martín; Lara, Sergio Lerma

    2016-04-01

    The aim of this study was to assess metabolic, cardiorespiratory, and neuromuscular fitness parameters in children with spastic cerebral palsy (CP) and to compare these findings with typically developing children. 40 children with CP (21 males, 19 females; mean age, 11.0±3.3 yr; range, 6.5-17.1 yr; Gross Motor Function Classification System levels 1 or 2) and 40 healthy, age- and sex-matched children completed a test battery that consisted of 8 tests and 28 measures that assessed cardio-respiratory fitness, energy expenditure, anaerobic endurance, muscle strength, agility, stability and flexibility. Children with CP had significantly lower performance (Pmetabolic tests than those of healthy children, Differences in neuromuscular measures of muscular strength, speed, agility, anaerobic endurance, and flexibility between groups were most apparent. Grouped differences in cardiorespiratory variables revealed a 25% difference in performance, whereas grouped differences in metabolic and neuromuscular measures were 43% and 60%, respectively. The physical fitness of contemporary children with CP is significantly less than healthy, age-matched children. Significant differences in neuromuscular measures between groups can aid in the identification of specific fitness abilities in need of improvement in this population. PMID:27162775

  18. Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults.

    Science.gov (United States)

    Johnson, Nathan F; Gold, Brian T; Bailey, Alison L; Clasey, Jody L; Hakun, Jonathan G; White, Matthew; Long, Doug E; Powell, David K

    2016-05-01

    A growing body of evidence indicates that cardiorespiratory fitness attenuates some age-related cerebral declines. However, little is known about the role that myocardial function plays in this relationship. Brain regions with high resting metabolic rates, such as the default mode network (DMN), may be especially vulnerable to age-related declines in myocardial functions affecting cerebral blood flow (CBF). This study explored the relationship between a measure of myocardial mechanics, global longitudinal strain (GLS), and CBF to the DMN. In addition, we explored how cardiorespiratory affects this relationship. Participants were 30 older adults between the ages of 59 and 69 (mean age=63.73years, SD=2.8). Results indicated that superior cardiorespiratory fitness and myocardial mechanics were positively associated with DMN CBF. Moreover, results of a mediation analysis revealed that the relationship between GLS and DMN CBF was accounted for by individual differences in fitness. Findings suggest that benefits of healthy heart function to brain function are modified by fitness.

  19. Cardiorespiratory fitness modifies the relationship between myocardial function and cerebral blood flow in older adults.

    Science.gov (United States)

    Johnson, Nathan F; Gold, Brian T; Bailey, Alison L; Clasey, Jody L; Hakun, Jonathan G; White, Matthew; Long, Doug E; Powell, David K

    2016-05-01

    A growing body of evidence indicates that cardiorespiratory fitness attenuates some age-related cerebral declines. However, little is known about the role that myocardial function plays in this relationship. Brain regions with high resting metabolic rates, such as the default mode network (DMN), may be especially vulnerable to age-related declines in myocardial functions affecting cerebral blood flow (CBF). This study explored the relationship between a measure of myocardial mechanics, global longitudinal strain (GLS), and CBF to the DMN. In addition, we explored how cardiorespiratory affects this relationship. Participants were 30 older adults between the ages of 59 and 69 (mean age=63.73years, SD=2.8). Results indicated that superior cardiorespiratory fitness and myocardial mechanics were positively associated with DMN CBF. Moreover, results of a mediation analysis revealed that the relationship between GLS and DMN CBF was accounted for by individual differences in fitness. Findings suggest that benefits of healthy heart function to brain function are modified by fitness. PMID:26032886

  20. Cardiorespiratory fitness and digestive cancer mortality: findings from the Aerobics Center Longitudinal Study (ACLS)

    OpenAIRE

    Peel, J. Brent; Sui, Xuemei; Matthews, Charles E.; Adams, Swann A; Hébert, James R; Hardin, James W.; Timothy S Church; Blair, Steven N.

    2009-01-01

    Although higher levels of physical activity are inversely associated with risk of colon cancer, few prospective studies have evaluated overall digestive system cancer mortality in relation to cardiorespiratory fitness (CRF). The authors examined this association among 38,801 men aged 20−88 years and who performed a maximal treadmill exercise test at baseline in the Aerobics Center Longitudinal Study (Dallas, Texas) during 1974−2003. Mortality was assessed over 29 years of follow-up (1974−2003...

  1. Alpine Skiing With total knee ArthroPlasty (ASWAP): effects on strength and cardiorespiratory fitness.

    Science.gov (United States)

    Pötzelsberger, B; Stöggl, T; Lindinger, S J; Dirnberger, J; Stadlmann, M; Buchecker, M; Hofstaedter, T; Gordon, K; Müller, E

    2015-08-01

    This study investigated the effect of a 12-week recreational skiing intervention on lower limb muscle strength and cardiorespiratory fitness in participants with unilateral total knee arthroplasty (TKA). Twenty-seven older adults (70 ± 5 years) were assigned to the intervention (n = 13) or control group (n = 14) after surgery (2.5 ± 1 years). Leg muscle strength was measured using an IsoMed 2000 dynamometer and cardiorespiratory fitness was determined by cycle ergometry before and after the intervention as well as after an 8-week retention period. The skiing intervention led to increased muscle strength in the operated leg during unilateral single joint isometric extension (maximal force: 11%; P torque development: 24%; P < 0.05) and during the unilateral multi-joint isokinetic single leg strength test (8%; P < 0.05). This resulted in a decreased asymmetry index in the isokinetic test (13% to 5%; P < 0.05). These adaptations remained unchanged toward the retention test. No effect was observed for cardiorespiratory fitness. The results demonstrate that muscle contraction forces required during recreational skiing in individuals with TKA seem adequate and effective to increase quadriceps and hamstrings muscle strength in the initially weaker operated leg and to reduce an augmented post-operative asymmetry index.

  2. Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners

    Directory of Open Access Journals (Sweden)

    M. J. Laye

    2015-01-01

    Full Text Available High levels of cardiovascular fitness (CRF and physical activity (PA are associated with decreased mortality and risk to develop metabolic diseases. The independent contributions of CRF and PA to metabolic disease risk factors are unknown. We tested the hypothesis that runners who run consistently >50 km/wk and/or >2 marathons/yr for the last 5 years have superior metabolic fitness compared to matched sedentary subjects (CRF, age, gender, and BMI. Case-control recruitment of 31 pairs of runner-sedentary subjects identified 10 matched pairs with similar VO2max (mL/min/kg (similar-VO2max. The similar-VO2max group was compared with a group of age, gender, and BMI matched pairs who had the largest difference in VO2max (different-VO2max. Primary outcomes that defined metabolic fitness including insulin response to an oral glucose tolerance test, fasting lipids, and fasting insulin were superior in runners versus sedentary controls despite similar VO2max. Furthermore, performance (velocity at VO2max, running economy, improved exercise metabolism (lactate threshold, and skeletal muscle levels of mitochondrial proteins were superior in runners versus sedentary controls with similar VO2max. In conclusion subjects with a high amount of PA have more positive metabolic health parameters independent of CRF. PA is thus a good marker against metabolic diseases.

  3. Brain activation during dual-task processing is associated with cardiorespiratory fitness and performance in older adults

    Directory of Open Access Journals (Sweden)

    Chelsea N Wong

    2015-08-01

    Full Text Available Higher cardiorespiratory fitness is associated with better cognitive performance and enhanced brain activation. Yet, the extent to which cardiorespiratory fitness-related brain activation is associated with better cognitive performance is not well understood. In this cross-sectional study, we examined whether the association between cardiorespiratory fitness and executive function was mediated by greater prefrontal cortex activation in healthy older adults. Brain activation was measured during dual-task performance with functional magnetic resonance imaging in a sample of 128 healthy older adults (59-80 years. Higher cardiorespiratory fitness was associated with greater activation during dual-task processing in several brain areas including the anterior cingulate and supplementary motor cortex (ACC/SMA, thalamus and basal ganglia, right motor/somatosensory cortex and middle frontal gyrus, and left somatosensory cortex, controlling for age, sex, education, and gray matter volume. Of these regions, greater ACC/SMA activation mediated the association between cardiorespiratory fitness and dual-task performance. We provide novel evidence that cardiorespiratory fitness may support cognitive performance by facilitating brain activation in a core region critical for executive function.

  4. Cardiorespiratory fitness is a stronger indicator of cardiometabolic risk factors and risk prediction than self-reported physical activity levels.

    Science.gov (United States)

    Gray, Benjamin J; Stephens, Jeffrey W; Williams, Sally P; Davies, Christine A; Turner, Daniel; Bracken, Richard M

    2015-11-01

    This study investigated the relationships of self-reported physical activity levels and cardiorespiratory fitness in 81 males to assess which measurement is the greatest indicator of cardiometabolic risk. Physical activity levels were determined by the General Practice Physical Activity Questionnaire tool and cardiorespiratory fitness assessed using the Chester Step Test. Cardiovascular disease risk was estimated using the QRISK2, Framingham Lipids, Framingham body mass index and Joint British Societies' Guidelines-2 equations, and type 2 diabetes mellitus risk calculated using QDiabetes, Leicester Risk Assessment, Finnish Diabetes Risk Score and Cambridge Risk Score models. Categorising employees by cardiorespiratory fitness categories ('Excellent/Good' vs 'Average/Below Average') identified more differences in cardiometabolic risk factor (body mass index, waist circumference, total cholesterol, total cholesterol:high-density lipoprotein ratio, high-density lipoprotein cholesterol, triglycerides, HbA(1c)) scores than physical activity (waist circumference only). Cardiorespiratory fitness levels also demonstrated differences in all four type 2 diabetes mellitus risk prediction models and both the QRISK2 and Joint British Societies' Guidelines-2 cardiovascular disease equations. Furthermore, significant negative correlations (p < 0.001) were observed between individual cardiorespiratory fitness values and estimated risk in all prediction models. In conclusion, from this preliminary observational study, cardiorespiratory fitness levels reveal a greater number of associations with markers of cardiovascular disease or type 2 diabetes mellitus compared to physical activity determined by the General Practice Physical Activity Questionnaire tool. PMID:26361778

  5. Cardiorespiratory fitness, cardiovascular workload and risk factors among cleaners; a cluster randomized worksite intervention

    Directory of Open Access Journals (Sweden)

    Korshøj Mette

    2012-08-01

    Full Text Available Abstract Background Prevalence of cardiovascular risk factors is unevenly distributed among occupational groups. The working environment, as well as lifestyle and socioeconomic status contribute to the disparity and variation in prevalence of these risk factors. High physical work demands have been shown to increase the risk for cardiovascular disease and mortality, contrary to leisure time physical activity. High physical work demands in combination with a low cardiorespiratory fitness infer a high relative workload and an excessive risk for cardiovascular mortality. Therefore, the aim of this study is to examine whether a worksite aerobic exercise intervention will reduce the relative workload and cardiovascular risk factors by an increased cardiorespiratory fitness. Methods/design A cluster-randomized controlled trial is performed to evaluate the effect of the worksite aerobic exercise intervention on cardiorespiratory fitness and cardiovascular risk factors among cleaners. Cleaners are eligible if they are employed ≥ 20 hours/week, at one of the enrolled companies. In the randomization, strata are formed according to the manager the participant reports to. The clusters will be balanced on the following criteria: Geographical work location, gender, age and seniority. Cleaners are randomized to either I a reference group, receiving lectures concerning healthy living, or II an intervention group, performing worksite aerobic exercise “60 min per week”. Data collection will be conducted at baseline, four months and 12 months after baseline, at the worksite during working hours. The data collection will consist of a questionnaire-based interview, physiological testing of health and capacity-related measures, and objective diurnal measures of heart rate, physical activity and blood pressure. Primary outcome is cardiorespiratory fitness. Discussion Information is lacking about whether an improved cardiorespiratory fitness will affect

  6. Cardiorespiratory fitness and body mass index values in 9-year-old rural Norwegian children

    DEFF Research Database (Denmark)

    Resaland, G K; Mamen, A; Anderssen, S A;

    2009-01-01

    AIM: To describe cardiorespiratory fitness and body mass index (BMI) values in a representative population of 9-year-old Norwegian children in two rural communities and compare present values with previous findings. METHODS: Two hundred and fifty-nine 9-year-old children were invited, and 256......, children's BMI values seem to have increased substantially. This increase is most pronounced in girls. When assessing these differences using the PI, this increase is less marked. Comparing maximal oxygen uptake data with that in earlier Nordic studies, there is no evidence that fitness has declined among...

  7. Cardiorespiratory fitness in Flemish adolescents and its relationship with leisure-time physical activity, active travel to school and screen-based sedentariness

    OpenAIRE

    Seghers, Jan; Rutten, Cindy

    2010-01-01

    Introduction Cardiorespiratory fitness is a key component of overall physical fitness and has been identified as a powerful health index in youth (Anderssen et al., 2007). The apparently obvious positive association between cardiorespiratory fitness and physical activity still requires further research. Therefore, the main objective of this study was to evaluate the association of cardiorespiratory fitness with leisure-time physical activity, active travel to school and screen-based sedent...

  8. Low cardiorespiratory fitness levels and elevated blood pressure: what is the contribution of visceral adiposity?

    Science.gov (United States)

    Rhéaume, Caroline; Arsenault, Benoit J; Bélanger, Stéphane; Pérusse, Louis; Tremblay, Angelo; Bouchard, Claude; Poirier, Paul; Després, Jean-Pierre

    2009-07-01

    Individuals with poor cardiorespiratory fitness have higher blood pressure than fit individuals. Individuals with low fitness levels also tend to be characterized by higher visceral adiposity compared with physically fit individuals. We tested the hypothesis that the relationship between low fitness and elevated blood pressure could be related, at least in part, to the higher level of visceral adipose tissue often found among unfit individuals. This study included 407 asymptomatic, nondiabetic participants. Visceral adipose tissue was assessed by computed tomography, and fitness was measured by a progressive submaximal physical working capacity test. Participants in the highest visceral adipose tissue tertile showed the highest systolic and diastolic blood pressures, whereas participants in the highest fitness tertile had the lowest blood pressure values (Pfitness tertiles and then subdivided on the basis of visceral adipose tissue (high versus low), participants with a high visceral adipose tissue had higher systolic and diastolic blood pressure values (P=0.01), independent of their fitness category. Linear regression analyses showed that age and visceral adipose tissue, but not fitness, predicted systolic blood pressure (r(2)=0.11 [Pvisceral adipose tissue, and fitness, respectively) and diastolic blood pressure (r(2)=0.17 [Pvisceral adipose tissue, and fitness, respectively). Individuals with high visceral adipose tissue levels have higher blood pressure, independent of their fitness. Visceral adipose tissue may represent an important clinical target in the management of elevated blood pressure. PMID:19470873

  9. Cardiorespiratory fitness in 16 025 adults aged 18-91 years and associations with physical activity and sitting time

    DEFF Research Database (Denmark)

    Eriksen, L; Grønbaek, M; Helge, J W;

    2015-01-01

    fitness was estimated in 16 025 individuals aged 18-91 years from validated cycle ergometer exercise tests. Level of leisure time physical activity (sedentary, light, moderate, and vigorous) and daily sitting time in hours was obtained from a self-administered questionnaire. Men had 20-33% higher......Our aim was to provide up-to-date cardiorespiratory fitness reference data for adults of all ages and to investigate associations between cardiores-piratory fitness and leisure time physical activity as well as sitting time. In the Danish Health Examination Survey 2007-2008, cardiorespiratory...... cardiorespiratory fitness than women, depending on age, and cardiorespiratory fitness decreased by 0.26 and 0.23 mL/min/kg per year in men and women, respectively. Cardiorespiratory fitness was higher among participants who reported a high level of physical activity in leisure time compared with participants who...

  10. Do functional walk tests reflect cardiorespiratory fitness in sub-acute stroke?

    Directory of Open Access Journals (Sweden)

    Bayley Mark T

    2006-09-01

    Full Text Available Abstract Background and purpose The Six-Minute Walk Test (6MWT has been employed as a measure of functional capacity, but its relationship to cardiorespiratory fitness in stroke is not well established. Gait speed measured over short distances is commonly used as an index of walking competency following stroke. We evaluated the relationship between the 6MWT, aerobic fitness (VO2peak and walking competency in sub-acute stroke. Methods Thirty-six individuals (mean age ± SD, 64.6 ± 14.4 years; time post-stroke 16.2 ± 13.3 days were evaluated using the 6MWT (distance, speed, heart rate, a maximal exercise test (VO2peak, heart rate, exercise test duration, and walking competency using a five meter walk (speed, symmetry ratio. Correlation analyses were used to examine the relationships between these outcomes. Results There was a strong correlation between the 6MWT and five meter walk velocity for preferred (r = 0.79 and fast (r = 0.82 speed (p 2peak (r = 0.56, p Conclusion The speed selected during the 6MWT was strongly related to the velocities selected during the five meter walk distance (intermediate to the selected preferred and fast speeds. Although the 6MWT may be challenging to the cardiorespiratory system, it appears to be more strongly influenced by potential limits to walking speed rather than cardiorespiratory capacity. As a result, this test is not, by itself, an adequate measure of aerobic fitness early after stroke.

  11. Experiences from a randomised, controlled trial on cycling to school: does cycling increase cardiorespiratory fitness?

    OpenAIRE

    Børrestad, Line Anita Bjørkelund; Østergaard, Lars; Andersen, Lars Bo; Bere, Elling

    2012-01-01

    Aims: The objective of the present study was to investigate the effect of a 12-week randomised controlled cycling-to-school trial on cardiorespiratory fitness. Methods: A total of 53 10- to 13-year-old children from one public school were included. The children were randomised into either a cycling group or a control group. The cycling group was encouraged to cycle to and from school each day during a period of 12 weeks. Peak oxygen consumption (VO2peak) and anthropometrical data (weight and ...

  12. cardiorespiratory fitness is associated with hard and light intensity physical activity but not time spent sedentary in 10-14 year old schoolchildren: the HAPPY study.

    Directory of Open Access Journals (Sweden)

    Sarah J Denton

    Full Text Available BACKGROUND: Sedentary behaviour is a major risk factor for developing chronic diseases and is associated with low cardiorespiratory fitness in adults. It remains unclear how sedentary behaviour and different physical activity subcomponents are related to cardiorespiratory fitness in children. The purpose of this study was to assess how sedentary behaviour and different physical activity subcomponents are associated with 10-14 year-old schoolchildren's cardiorespiratory fitness. METHODS: 135 schoolchildren (81 girls, 12±1 year completed 7-day minute-by-minute habitual physical activity monitoring using triaxial accelerometers and undertook a maximal cardiorespiratory fitness test. RESULTS: After controlling for sex, age, ethnicity, socioeconomic status and total wear time, light physical activity (1.5-2.9 METs was negatively associated (β = -.24, p.05. Sedentary to active transitions revealed little variability between cardiorespiratory fitness tertiles. CONCLUSIONS: Hard physical activity (≥9 METs holds greater potential for cardiorespiratory fitness compared to physical activity of lower intensities. There was no relationship between sedentary behaviour and cardiorespiratory fitness. These findings suggest that, for children, advice should focus on higher intensity physical activity and not sedentary behaviour as a means to maintain or improve cardiorespiratory fitness. Future research should explore longitudinal relationships between hard physical activity, cardiorespiratory fitness and health parameters.

  13. Differential cross-sectional associations of work- and leisure-time sitting, with cardiorespiratory and muscular fitness among working adults

    DEFF Research Database (Denmark)

    Saidj, Madina; Jørgensen, Torben; Jacobsen, Rikke K;

    2014-01-01

    of cardiorespiratory fitness (step test estimated VO 2Max, systolic and diastolic blood pressure) and muscular fitness (handgrip strength, lower limb extension power). Associations were explored by linear regression. Results Leisure-time sitting time was significantly (P..., systolic blood pressure and handgrip strength among adults

  14. Cardiorespiratory fitness, pulmonary function and C-reactive protein levels in nonsmoking individuals with diabetes

    International Nuclear Information System (INIS)

    The objective of this study was to evaluate cardiorespiratory fitness and pulmonary function and the relationship with metabolic variables and C-reactive protein (CRP) plasma levels in individuals with diabetes mellitus (DM). Nineteen men with diabetes and 19 age- and gender-matched control subjects were studied. All individuals were given incremental cardiopulmonary exercise and pulmonary function tests. In the exercise test, maximal workload (158.3±22.3 vs 135.1±25.2, P=0.005), peak heart rate (HRpeak: 149±12 vs 139±10, P=0.009), peak oxygen uptake (VO2peak: 24.2±3.2 vs 18.9±2.8, P<0.001), and anaerobic threshold (VO2VT: 14.1±3.4 vs 12.2±2.2, P=0.04) were significantly lower in individuals with diabetes than in control subjects. Pulmonary function test parameters, blood pressure, lipid profile (triglycerides, HDL, LDL, and total cholesterol), and CRP plasma levels were not different in control subjects and individuals with DM. No correlations were observed between hemoglobin A1C (HbA1c), CRP and pulmonary function test and cardiopulmonary exercise test performance. In conclusion, the results demonstrate that nonsmoking individuals with DM have decreased cardiorespiratory fitness that is not correlated with resting pulmonary function parameters, HbA1c, and CRP plasma levels

  15. Cardiorespiratory fitness, pulmonary function and C-reactive protein levels in nonsmoking individuals with diabetes

    Energy Technology Data Exchange (ETDEWEB)

    Francisco, C.O.; Catai, A.M.; Moura-Tonello, S.C.G. [Universidade Federal de São Carlos, Departamento de Fisioterapia, São Carlos, SP, Brasil, Departamento de Fisioterapia, Universidade Federal de São Carlos, São Carlos, SP (Brazil); Lopes, S.L.B. [Universidade Federal de São Carlos, Departamento de Medicina, São Carlos, SP, Brasil, Departamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP (Brazil); Benze, B.G. [Universidade Federal de São Carlos, Departamento de Estatística, São Carlos, SP, Brasil, Departamento de Estatística, Universidade Federal de São Carlos, São Carlos, SP (Brazil); Del Vale, A.M.; Leal, A.M.O. [Universidade Federal de São Carlos, Departamento de Medicina, São Carlos, SP, Brasil, Departamento de Medicina, Universidade Federal de São Carlos, São Carlos, SP (Brazil)

    2014-04-15

    The objective of this study was to evaluate cardiorespiratory fitness and pulmonary function and the relationship with metabolic variables and C-reactive protein (CRP) plasma levels in individuals with diabetes mellitus (DM). Nineteen men with diabetes and 19 age- and gender-matched control subjects were studied. All individuals were given incremental cardiopulmonary exercise and pulmonary function tests. In the exercise test, maximal workload (158.3±22.3 vs 135.1±25.2, P=0.005), peak heart rate (HR{sub peak}: 149±12 vs 139±10, P=0.009), peak oxygen uptake (VO{sub 2peak}: 24.2±3.2 vs 18.9±2.8, P<0.001), and anaerobic threshold (VO{sub 2VT}: 14.1±3.4 vs 12.2±2.2, P=0.04) were significantly lower in individuals with diabetes than in control subjects. Pulmonary function test parameters, blood pressure, lipid profile (triglycerides, HDL, LDL, and total cholesterol), and CRP plasma levels were not different in control subjects and individuals with DM. No correlations were observed between hemoglobin A1C (HbA1c), CRP and pulmonary function test and cardiopulmonary exercise test performance. In conclusion, the results demonstrate that nonsmoking individuals with DM have decreased cardiorespiratory fitness that is not correlated with resting pulmonary function parameters, HbA1c, and CRP plasma levels.

  16. White matter microstructure mediates the relationship between cardiorespiratory fitness and spatial working memory in older adults.

    Science.gov (United States)

    Oberlin, Lauren E; Verstynen, Timothy D; Burzynska, Agnieszka Z; Voss, Michelle W; Prakash, Ruchika Shaurya; Chaddock-Heyman, Laura; Wong, Chelsea; Fanning, Jason; Awick, Elizabeth; Gothe, Neha; Phillips, Siobhan M; Mailey, Emily; Ehlers, Diane; Olson, Erin; Wojcicki, Thomas; McAuley, Edward; Kramer, Arthur F; Erickson, Kirk I

    2016-05-01

    White matter structure declines with advancing age and has been associated with a decline in memory and executive processes in older adulthood. Yet, recent research suggests that higher physical activity and fitness levels may be associated with less white matter degeneration in late life, although the tract-specificity of this relationship is not well understood. In addition, these prior studies infrequently associate measures of white matter microstructure to cognitive outcomes, so the behavioral importance of higher levels of white matter microstructural organization with greater fitness levels remains a matter of speculation. Here we tested whether cardiorespiratory fitness (VO2max) levels were associated with white matter microstructure and whether this relationship constituted an indirect pathway between cardiorespiratory fitness and spatial working memory in two large, cognitively and neurologically healthy older adult samples. Diffusion tensor imaging was used to determine white matter microstructure in two separate groups: Experiment 1, N=113 (mean age=66.61) and Experiment 2, N=154 (mean age=65.66). Using a voxel-based regression approach, we found that higher VO2max was associated with higher fractional anisotropy (FA), a measure of white matter microstructure, in a diverse network of white matter tracts, including the anterior corona radiata, anterior internal capsule, fornix, cingulum, and corpus callosum (PFDR-correctedgender, and education. Further, a statistical mediation analysis revealed that white matter microstructure within these regions, among others, constituted a significant indirect path between VO2max and spatial working memory performance. These results suggest that greater aerobic fitness levels are associated with higher levels of white matter microstructural organization, which may, in turn, preserve spatial memory performance in older adulthood. PMID:26439513

  17. White matter microstructure mediates the relationship between cardiorespiratory fitness and spatial working memory in older adults.

    Science.gov (United States)

    Oberlin, Lauren E; Verstynen, Timothy D; Burzynska, Agnieszka Z; Voss, Michelle W; Prakash, Ruchika Shaurya; Chaddock-Heyman, Laura; Wong, Chelsea; Fanning, Jason; Awick, Elizabeth; Gothe, Neha; Phillips, Siobhan M; Mailey, Emily; Ehlers, Diane; Olson, Erin; Wojcicki, Thomas; McAuley, Edward; Kramer, Arthur F; Erickson, Kirk I

    2016-05-01

    White matter structure declines with advancing age and has been associated with a decline in memory and executive processes in older adulthood. Yet, recent research suggests that higher physical activity and fitness levels may be associated with less white matter degeneration in late life, although the tract-specificity of this relationship is not well understood. In addition, these prior studies infrequently associate measures of white matter microstructure to cognitive outcomes, so the behavioral importance of higher levels of white matter microstructural organization with greater fitness levels remains a matter of speculation. Here we tested whether cardiorespiratory fitness (VO2max) levels were associated with white matter microstructure and whether this relationship constituted an indirect pathway between cardiorespiratory fitness and spatial working memory in two large, cognitively and neurologically healthy older adult samples. Diffusion tensor imaging was used to determine white matter microstructure in two separate groups: Experiment 1, N=113 (mean age=66.61) and Experiment 2, N=154 (mean age=65.66). Using a voxel-based regression approach, we found that higher VO2max was associated with higher fractional anisotropy (FA), a measure of white matter microstructure, in a diverse network of white matter tracts, including the anterior corona radiata, anterior internal capsule, fornix, cingulum, and corpus callosum (PFDR-correctedmicrostructure within these regions, among others, constituted a significant indirect path between VO2max and spatial working memory performance. These results suggest that greater aerobic fitness levels are associated with higher levels of white matter microstructural organization, which may, in turn, preserve spatial memory performance in older adulthood.

  18. Effect of a primary health-care-based controlled trial for cardiorespiratory fitness in refugee women

    Directory of Open Access Journals (Sweden)

    Johansson Sven-Erik

    2010-08-01

    Full Text Available Abstract Background Refugee women have a high risk of coronary heart disease with low physical activity as one possible mediator. Furthermore, cultural and environmental barriers to increasing physical activity have been demonstrated. The aim of the study was to evaluate the combined effect of an approximate 6-month primary health care- and community-based exercise intervention versus an individual written prescription for exercise on objectively assessed cardiorespiratory fitness in low-active refugee women. Methods A controlled clinical trial, named "Support for Increased Physical Activity", was executed among 243 refugee women recruited between November 2006 and April 2008 from two deprived geographic areas in southern Stockholm, Sweden. One geographic area provided the intervention group and the other area the control group. The control group was on a higher activity level at both baseline and follow-up, which was taken into consideration in the analysis by applying statistical models that accounted for this. Relative aerobic capacity and fitness level were assessed as the two main outcome measures. Results The intervention group increased their relative aerobic capacity and the percentage with an acceptable fitness level (relative aerobic capacity > 23 O2ml·kg·min-1 to a greater extent than the control group between baseline and the 6-month follow-up, after adjusting for possible confounders (P = 0.020. Conclusions A combined primary health-care and community-based exercise programme (involving non-profit organizations can be an effective strategy to increase cardiorespiratory fitness among low-active refugee women. Trial Registration ClinicalTrials.gov ID: NCT00747942

  19. Associations of sedentary behaviour, physical activity, blood pressure and anthropometric measures with cardiorespiratory fitness in children with cerebral palsy.

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    Jennifer M Ryan

    Full Text Available Children with cerebral palsy (CP have poor cardiorespiratory fitness in comparison to their peers with typical development, which may be due to low levels of physical activity. Poor cardiorespiratory fitness may contribute to increased cardiometabolic risk.The aim of this study was to determine the association between sedentary behaviour, physical activity and cardiorespiratory fitness in children with CP. An objective was to determine the association between cardiorespiratory fitness, anthropometric measures and blood pressure in children with CP.This study included 55 ambulatory children with CP [mean (SD age 11.3 (0.2 yr, range 6-17 yr; Gross Motor Function Classification System (GMFCS levels I and II]. Anthropometric measures (BMI, waist circumference and waist-height ratio and blood pressure were taken. Cardiorespiratory fitness was measured using a 10 m shuttle run test. Children were classified as low, middle and high fitness according to level achieved on the test using reference curves. Physical activity was measured by accelerometry over 7 days. In addition to total activity, time in sedentary behaviour and light, moderate, vigorous, and sustained moderate-to-vigorous activity (≥10 min bouts were calculated.Multiple regression analyses revealed that vigorous activity (β = 0.339, p<0.01, sustained moderate-to-vigorous activity (β = 0.250, p<0.05 and total activity (β = 0.238, p<0.05 were associated with level achieved on the shuttle run test after adjustment for age, sex and GMFCS level. Children with high fitness spent more time in vigorous activity than children with middle fitness (p<0.05. Shuttle run test level was negatively associated with BMI (r2 = -0.451, p<0.01, waist circumference (r2 = -0.560, p<0.001, waist-height ratio (r2 = -0.560, p<0.001 and systolic blood pressure (r2 = -0.306, p<0.05 after adjustment for age, sex and GMFCS level.Participation in physical activity, particularly at a vigorous intensity, is

  20. Daily energy expenditure, cardiorespiratory fitness and glycaemic control in people with type 1 diabetes.

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    John Joseph Valletta

    Full Text Available OBJECTIVE: Encouraging daily physical activity improves cardiorespiratory fitness and many cardiovascular risk factors. However, increasing physical activity often creates a challenge for people with type 1 diabetes, because of difficulties maintaining euglycemia in the face of altered food intake and adjustments to insulin doses. Our aim was to examine the triangular relationship between glucose control measured by continuous glucose monitoring system (CGMS, objective measures of total daily energy expenditure (TEE recorded by a multi-sensory monitoring device, and cardiorespiratory fitness (CRF, in free-living subjects with type 1 diabetes. RESEARCH DESIGN AND METHODS: Twenty-three individuals (12 women with type 1 diabetes who were free from micro- and macrovascular complications were recruited. TEE and glucose control were monitored simultaneously for up to 12 days, using a multi-sensory device and CGMS respectively. CRF was recorded as V02 max from a maximal treadmill test with the Bruce protocol. RESULTS: Subjects (mean±SD were aged 37±11 years, with BMI = 26.5±5.1 kg.m⁻², HbA1c = 7.7±1.3% (61±14 mmol/mol and V02 max (ml.min⁻¹.kg⁻¹  = 39.9±8.4 (range 22.4-58.6. TEE (36.3±5.5 kcal.kg⁻¹.day⁻¹ was strongly associated with CRF(39.9±8.4 ml.min⁻¹.kg⁻¹ independently of sex (r = 0.63, p<0.01. However, neither TEE (r = -0.20, p = 0.36 nor CRF (r = -0.20, p = 0.39; adjusted for sex, were significantly associated with mean glycaemia measured by CGMS. CONCLUSION: Higher levels of energy expenditure (due to a more active lifestyle are associated with increased cardiorespiratory fitness, but not necessarily better glycaemic control. Since increased levels of energy expenditure and good glycaemic control are both needed to protect against diabetes-related complications our data suggest they need to be achieved independently.

  1. Sickness Presenteeism Among Health Care Workers and the Effect of BMI, Cardiorespiratory Fitness, and Muscle Strength

    DEFF Research Database (Denmark)

    Christensen, Jeanette Reffstrup; Kongstad, Malte Bue; Sjøgaard, Gisela;

    2015-01-01

    OBJECTIVES: The primary objective of this study was to assess the relationship between sickness presenteeism and body mass index (BMI), cardiorespiratory fitness (CRF), and maximal voluntary contraction (MVC). METHODS: Female health care workers (n = 139) were analyzed cross-sectional as well...... as longitudinal after 3 and 12-month follow-up. Sickness presenteeism was assessed as a summed score using validated questions from three questionnaires: Health and Work Performance Questionnaire, Work Ability Index, and Quantity and Quality Method. CRF was assessed by a maximal cycling test and MVC from four...... muscle groups. RESULTS: Significant relationships were found between sickness presenteeism and BMI as well as MVC both cross-sectional and as changes over 3 months. Participants with BMI more than 30 kg/m had significantly higher sickness presenteeism than those with BMI less than 25 kg/m. CONCLUSIONS...

  2. Prospective association of adiposity and cardiorespiratory fitness with cardiovascular risk factors in healthy children

    DEFF Research Database (Denmark)

    Klakk, H; Grøntved, A; Møller, N C;

    2014-01-01

    This study aimed to examine the prospective association of three different measures of adiposity and cardiorespiratory fitness (CRF) with 2-year change in cardiovascular disease (CVD) risk factors in children. Two-year longitudinal data in schoolchildren aged 7-11 years (n = 365-729) was used...... at baseline was associated with increased CVD risk factor levels at follow-up. The magnitudes of associations were similar regardless of adiposity measure [TBF%: β 0.30, 95% confidence interval (CI): 0.21-0.39; BMI: β 0.24, 95% CI: 0.14-0.33; WC: β 0.20, 95% CI: 0.10-0.31], and no evidence of nonlinear...... relationships was observed. We found less strong associations of CRF with increase in CVD risk factor levels after adjusting for adiposity; however, increasing CRF was still favorably associated with decrease in CVD risk factor levels among boys. Results suggest that any effort to shift the population...

  3. Evidence of the Role of Physical Activity and Cardiorespiratory Fitness in the Prevention of Coronary Heart Disease.

    Science.gov (United States)

    Leon, Arthur S.; Norstrom, Jane

    1995-01-01

    This paper presents epidemiologic evidence on the contributions of physical inactivity and reduced cardiorespiratory fitness to risk of coronary heart disease (CHD). The types and dose of physical activity to reduce risk of CHD and plausible biologic mechanisms for the partial protective effect are reviewed. (Author/SM)

  4. Effect of Cardiorespiratory Training on Aerobic Fitness and Carryover to Activity In Children with Cerebral Palsy: A Systematic Review

    Science.gov (United States)

    Butler, Jane M.; Scianni, Aline; Ada, Louise

    2010-01-01

    The question under consideration was does cardiorespiratory training improve aerobic fitness in children with cerebral palsy and is there any carryover into activity? The study design consisted of a systematic review of randomized trials using the Cochrane Collaboration guidelines. Participants were children of school age with cerebral palsy.…

  5. Influence of Cardiorespiratory Fitness on PPARG mRNA Expression Using Monozygotic Twin Case Control

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    Marcos Roberto Queiroga

    2015-01-01

    Full Text Available The influence of cardiorespiratory fitness (VO2max on anthropometric variables and PPARG mRNA expression was investigated. Monozygotic twin pairs aged 11–18 years were grouped into discordant (D and concordant (C high and low VO2max groups. VO2max was determined by progressive maximal exercise test on treadmill with gas exchange analysis. Body mass (BM, BMI, waist circumference (WC, triceps (TR, and subscapular (SB skinfold thicknesses were measured. Twins from the discordant group had differences in VO2max values (D-high = 45.9±10.0 versus D-low = 32.4±10.6 mL·kg−1·min−1, P=0.025, while no differences were found in the concordant group (C-high = 42.4±9.2 versus C-low = 38.8±9.8 mL·kg−1·min−1, P=0.952. In discordant group, VO2max was negatively correlated with TR + SB (r=-0.540, P=0.021 and positively correlated with PPARG expression in leukocytes (r=0.952, P=0.001. Moreover, PPARG expression was directly correlated with BM (r=0.714, P=0.047 and height (r=0.762, P=0.028. In concordant twins, VO2max was inversely correlated with BM (r=-0.290, P=0.027, BMI (r=-0.472, P=0.001, WC (r=-0.426, P=0.001, and TR + SB (r=-0.739, P=0.001. Twins D-high had 1.78-fold greater PPARG expression when compared with twins D-low (P=0.048. In conclusion, the cardiorespiratory fitness may modulate PPARG expression in childhood and adolescence, independently of the genetic background.

  6. Influence of Cardiorespiratory Fitness on PPARG mRNA Expression Using Monozygotic Twin Case Control

    Science.gov (United States)

    Queiroga, Marcos Roberto; Barbieri, Ricardo Augusto; Ferreira, Sandra Aires; Luchessi, André Ducati; Hirata, Rosario Dominguez Crespo; Hirata, Mario Hiroyuki; Kokubun, Eduardo

    2015-01-01

    The influence of cardiorespiratory fitness (VO2max) on anthropometric variables and PPARG mRNA expression was investigated. Monozygotic twin pairs aged 11–18 years were grouped into discordant (D) and concordant (C) high and low VO2max groups. VO2max was determined by progressive maximal exercise test on treadmill with gas exchange analysis. Body mass (BM), BMI, waist circumference (WC), triceps (TR), and subscapular (SB) skinfold thicknesses were measured. Twins from the discordant group had differences in VO2max values (D-high = 45.9 ± 10.0 versus D-low = 32.4 ± 10.6 mL·kg−1·min−1, P = 0.025), while no differences were found in the concordant group (C-high = 42.4 ± 9.2 versus C-low = 38.8 ± 9.8 mL·kg−1·min−1, P = 0.952). In discordant group, VO2max was negatively correlated with TR + SB (r = −0.540, P = 0.021) and positively correlated with PPARG expression in leukocytes (r = 0.952, P = 0.001). Moreover, PPARG expression was directly correlated with BM (r = 0.714, P = 0.047) and height (r = 0.762, P = 0.028). In concordant twins, VO2max was inversely correlated with BM (r = −0.290, P = 0.027), BMI (r = −0.472, P = 0.001), WC (r = −0.426, P = 0.001), and TR + SB (r = −0.739, P = 0.001). Twins D-high had 1.78-fold greater PPARG expression when compared with twins D-low (P = 0.048). In conclusion, the cardiorespiratory fitness may modulate PPARG expression in childhood and adolescence, independently of the genetic background. PMID:25879043

  7. Impact of cardiorespiratory fitness on the obesity paradox in patients with systolic heart failure.

    Science.gov (United States)

    Clark, Adrienne L; Fonarow, Gregg C; Horwich, Tamara B

    2015-01-15

    Although high body mass index (BMI) is associated with improved outcomes in established heart failure (HF), the impact of cardiorespiratory fitness on this obesity paradox is less clear. We studied 1,675 patients with systolic HF who underwent cardiopulmonary exercise testing at a single university center (77.4% men, mean age 52.2 ± 11.6 years, mean left ventricular ejection fraction 23.2 ± 7.1% and New York Heart Association class III or IV in 79.1%). We evaluated 2-year survival in patients stratified by both BMI (normal 18.5 to 24.9 kg/m(2)[reference], overweight 25 to 29.9 kg/m(2), obese ≥30.0 kg/m(2)) and by peak oxygen uptake (PKVO2; high >14 ml/kg/minute, low ≤14 ml/kg/minute). At 2 years, BMI category was significantly associated with outcomes for the low PKVO2 group (p obese patients had decreased risk of death free from urgent status 1A heart transplant or ventricular assist device placement after multivariate adjustment compared with normal BMI (hazard ratio [HR] 0.64, 95% confidence interval [CI] 0.44 to 0.91, p = 0.01); no significant difference was observed for overweight patients (HR 0.91, 95% CI 0.66 to 1.25, p = 0.5). In the high PKVO2 group, no relation was seen (overweight BMI HR 0.75, 95% CI 0.43 to 1.32, p = 0.3; obese HR 0.87, 95% CI 0.43 to 1.75, p = 0.7). In conclusion, the obesity paradox was only observed in patients with lower cardiorespiratory fitness in this advanced systolic HF cohort, indicating that improved functional capacity may attenuate the obesity paradox.

  8. Low cardiorespiratory fitness in people at risk for type 2 diabetes: early marker for insulin resistance

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    Leite Silmara AO

    2009-09-01

    Full Text Available Abstract Purpose There is a significant association between insulin resistance and low cardiorespiratory fitness in nondiabetic subjects. In a population with risk factors for type 2 diabetes (T2DM, before they are insulin resistant, we investigated low exercise capacity (VO2max as an early marker of impaired insulin sensitivity in order to determine earlier interventions to prevent development of insulin resistance syndrome (IRS and T2DM. Methods Cross-sectional analyses of data on 369 (78 men and 291 women people at risk for IRS and T2DM, aged 45.6 +/- 10 years (20-65 years old from the Community Diabetes Prevention Project in Minnesota were carried out. The cardiorespiratory fitness (VO2max by respiratory gas exchange and bicycle ergometer were measured in our at risk non insulin resistant population and compared with a control group living in the same geographic area. Both groups were equally sedentary, matched for age, gender and BMI. Results The most prevalent abnormality in the study population was markedly low VO2max when compared with general work site screening control group, (n = 177; 137F; 40 M, mean age 40 ± 11 years; BMI = 27.8 ± 6.1 kg/m2. Individuals at risk for IRS and T2DM had a VO2max (22 ± 6 ml/kg/min 15% lower than the control group VO2max (26 ± 9 ml/kg/min (p 2max was inversely correlated with HOMA-IR (r = -0.30, p Conclusions Decreased VO2max is correlated with impaired insulin sensitivity and was the most prevalent abnormality in a population at risk for IRS and T2DM but without overt disease. This raises the possibility that decreased VO2 max is among the earliest indicators of IRS and T2DM therefore, an important risk factor for disease progression.

  9. State adaptation reserves cardiorespiratory system first-year students with varying degrees of physical fitness in terms of treadmill test

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    Levchenko V.A.

    2014-03-01

    Full Text Available Purpose : to examine the state of the cardiorespiratory system in terms of the stress test in first-year students with different levels of fitness. Material : the study involved 43 students, of which 18 boys and 25devushek basic medical group. The study used a treadmill, a pulse oximeter, spirometer. Results : more adjustment disorders were detected in students that are not involved in physical education at school. Decreased ability of the cardiorespiratory system to maintain proper oxygen supply of the organism in the stress test. This is not observed in students who were attending school in addition sports clubs. Found that students with low tolerance to physical exercise need a separate program of physical training, the dynamic control of the teachers and the need for additional medical examination. Conclusions : the treadmill test is an ideal way of revealing hidden maladjustment cardiorespiratory system in adolescence.

  10. Physical activity enhances metabolic fitness independently of cardiorespiratory fitness in marathon runners

    DEFF Research Database (Denmark)

    Laye, M J; Nielsen, M B; Hansen, L S;

    2015-01-01

    High levels of cardiovascular fitness (CRF) and physical activity (PA) are associated with decreased mortality and risk to develop metabolic diseases. The independent contributions of CRF and PA to metabolic disease risk factors are unknown. We tested the hypothesis that runners who run......). The similar-VO2max group was compared with a group of age, gender, and BMI matched pairs who had the largest difference in VO2max (different-VO2max). Primary outcomes that defined metabolic fitness including insulin response to an oral glucose tolerance test, fasting lipids, and fasting insulin were superior...... consistently >50 km/wk and/or >2 marathons/yr for the last 5 years have superior metabolic fitness compared to matched sedentary subjects (CRF, age, gender, and BMI). Case-control recruitment of 31 pairs of runner-sedentary subjects identified 10 matched pairs with similar VO2max (mL/min/kg) (similar-VO2max...

  11. Physical Activity Enhances Metabolic Fitness Independently of Cardiorespiratory Fitness in Marathon Runners

    OpenAIRE

    Laye, M. J.; Nielsen, M. B.; Hansen, L. S.; T. Knudsen; Pedersen, B K

    2015-01-01

    High levels of cardiovascular fitness (CRF) and physical activity (PA) are associated with decreased mortality and risk to develop metabolic diseases. The independent contributions of CRF and PA to metabolic disease risk factors are unknown. We tested the hypothesis that runners who run consistently >50 km/wk and/or >2 marathons/yr for the last 5 years have superior metabolic fitness compared to matched sedentary subjects (CRF, age, gender, and BMI). Case-control recruitment of 31 pairs of ru...

  12. Association of low muscle mass and combined low muscle mass and visceral obesity with low cardiorespiratory fitness.

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    Tae Nyun Kim

    Full Text Available Previous studies have shown that low cardiorespiratory fitness (CRF, visceral obesity and low muscle mass may share pathophysiological mechanisms, such as insulin resistance and chronic inflammation. In this study, we investigated whether low CRF is associated with low muscle mass, visceral obesity, and visceral obesity combined with low muscle mass.The associations between CRF and low muscle mass and combined low muscle mass and visceral obesity were examined in 298 apparently healthy adults aged 20-70 years. Low muscle mass was defined using a skeletal muscle mass index (SMI that was calculated using dual energy X-ray absorptiometry. Visceral obesity was defined as a visceral fat area (VFA exceeding 100 cm2 in women and 130 cm2 in men. We classified the participants into 4 low muscle mass/visceral obesity groups according to SMI and VFA. CRF was measured using a cycle ergometer test.CRF level correlated positively with SMI and negatively with VFA. Individuals with low muscle mass had lower CRF values than those without low muscle mass. After adjustment for age, sex, lifestyle factors, and markers for insulin resistance and inflammation, participants in the lowest quartile of CRF had an odds ratio (OR for low muscle mass of 4.98 compared with those in the highest quartile (95% confidence interval (CI = 1.19-12.99; P for trend = 0.001 and an OR for combined low muscle mass and visceral obesity of 31.46 (95% CI = 4.31-229.68; P for trend = 0.001.Individuals with lower CRF exhibited increased risk of low muscle mass and combined low muscle mass and visceral obesity. These results suggest that low CRF may be a potential indicator for low muscle mass and combined low muscle mass and visceral obesity in Korean adults.

  13. Construct validation of a non-exercise measure of cardiorespiratory fitness in older adults

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    Kramer Arthur F

    2010-02-01

    Full Text Available Abstract Background Cardiorespiratory fitness (CRF is associated with a decreased risk of all-cause mortality but is rarely assessed in medical settings due to burdens of time, cost, risk, and resources. The purpose of this study was to test the construct validity of a regression equation developed by Jurca and colleagues (2005 to estimate CRF without exercise testing in community dwelling older adults. Methods Participants (n = 172 aged 60 to 80 years with no contraindications to submaximal or maximal exercise testing completed a maximal graded exercise test (GXT and the submaximal Rockport 1-mile walk test on separate occasions. Data included in the regression equation (age, sex, body mass index, resting heart rate, and physical activity were obtained via measurement or self-report. Participants also reported presence of cardiovascular conditions. Results The multiple R for the regression equation was .72, p and CRF estimated from this equation was significantly correlated with the MET value from the GXT (r = 0.66 and with CRF estimated from submaximal field testing (r = 0.67. All three CRF indices were significantly and inversely associated with reporting more cardiovascular conditions. Conclusions This research provides preliminary evidence that a non-exercise estimate of CRF is at least as valid as field test estimates of CRF and represents a low-risk, low-cost, and expedient method for estimating fitness in older adults.

  14. HIGHER CARDIORESPIRATORY FITNESS IN OLDER TRAINED WOMEN IS DUE TO PRESERVED STROKE VOLUME

    Directory of Open Access Journals (Sweden)

    Shilpa Dogra

    2012-12-01

    Full Text Available Previous literature has shown that sedentary older women rely on peripheral adaptations to improve cardiorespiratory fitness with endurance training i.e. they show minimal increases in central parameters (cardiac output, Q in response to endurance training. The purpose of this study therefore was to determine whether endurance trained older women were able to preserve maximal exercise Q and were characterized by a high stroke volume (SV when compared to physically inactive older women. Trained (n = 7 and untrained (n = 1 0 women attended two maximal and one submaximal laboratory session. Breath-by-breath analysis was conducted using mass spectrometry and Q was assessed using acetylene open circuit inert gas wash-in. Multivariate analysis of variance and paired samples t-tests were used to determine between and within group differences. Trained women had a significantly higher VO2max (37.5 vs. 24.1 ml-1·kg·min-1 compared to untrained women. There were no differences for peripheral oxygen extraction (VO2/Q at either submaximal or maximal work rates; however trained women had a significantly higher SV at maximal (119.3 vs. 94.6 ml exercise compared to untrained women. In both trained and untrained women, SV did not rise significantly between submaximal and maximal exercise. Conclusion: Highly fit, endurance trained older women are able to preserve central parameters of VO2max. Peripheral oxygen extraction is similar between older trained and untrained women

  15. Combined impact of cardiorespiratory fitness and visceral adiposity on metabolic syndrome in overweight and obese adults in Korea.

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    Sue Kim

    Full Text Available BACKGROUND: Obesity, especially visceral obesity, is known to be an important correlate for cardiovascular disease and increased mortality. On the other hand, high cardiorespiratory fitness is suggested to be an effective contributor for reducing this risk. This study was conducted to determine the combined impact of cardiorespiratory fitness and visceral adiposity, otherwise known as fitness and fatness, on metabolic syndrome in overweight and obese adults. METHODS: A total of 232 overweight and obese individuals were grouped into four subtypes according to their fitness level. This was measured by recovery heart rate from a step test in addition to visceral adiposity defined as the visceral adipose tissue area to subcutaneous adipose tissue area ratio (VAT/SAT ratio. Associations of fitness and visceral fatness were analyzed in comparison with the prevalence of metabolic syndrome. RESULTS: The high visceral fat and low fitness group had the highest prevalence of metabolic syndrome [Odds Ratio (OR 5.02; 95% Confidence Interval (CI 1.85-13.61] compared with the reference group, which was the low visceral adiposity and high fitness group, after adjustments for confounding factors. Viscerally lean but unfit subjects were associated with a higher prevalence of metabolic syndrome than more viscerally obese but fit subjects (OR 3.42; 95% CI 1.27-9.19, and OR 2.70; 95% CI 1.01-7.25, respectively. CONCLUSIONS: Our study shows that visceral obesity and fitness levels are cumulatively associated with a higher prevalence of metabolic syndrome in healthy overweight and obese adults. This suggests that cardiorespiratory fitness is a significant modifier in the relation of visceral adiposity to adverse metabolic outcomes in overweight and obese individuals.

  16. Associations between physical activity, cardiorespiratory fitness, and obesity in Mexican children

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    Karla I Galavíz

    2012-10-01

    Full Text Available OBJECTIVE: To examine the independent relation of physical activity (PA and cardiorespiratory fitness (fitness with measures of obesity in Mexican children. MATERIALS AND METHODS: Children (N=193 in 5th and 6th grade from Guadalajara participated. Body mass index (BMI, sum of skinfolds (SS and waist circumference (WC were measured. PA was measured over four days using pedometry and fitness was measured using the 20 meter shuttle-run test. RESULTS: Fitness and PA were negatively related to the obesity measures in boys and girls (r=-0.57 to -0.64 and r=-0.18 to -0.23 respectively. Age adjusted significant differences in WC, BMI, and SS were observed between the lowest and highest fitness tertiles for boys and girls (pOBJETIVO: Examinar la relación independiente entre actividad física (AF y acondicionamiento cardiorrespiratorio (fitness con obesidad en niños mexicanos. MATERIAL Y MÉTODOS: Participaron 193 niños de Guadalajara en 5to y 6to grado de primaria. Se midieron índice de masa corporal (IMC, suma de pliegues cutáneos (SP y circunferencia de cintura (CC. La AF se midió con podometría durante cuatro días y acondicionamiento usando la prueba de 20 metros shuttle-run. RESULTADOS: Acondicionamiento y AF estuvieron negativamente relacionados con obesidad en niños y niñas (r=-0.57 a -0.64 y r=-0.18 a -0.23 respectivamente. Ajustando por edad, se observaron diferencias significativas en CC, IMC y SP entre los terciles de acondicionamiento bajo y alto en niños y niñas (p<.01. Ajustando por edad, género y AF, el acondicionamiento explicó de 23 a 34% de la varianza en CC (r²=0.23, p<.01, IMC (r²=0.23, p<.01 y SP (r²=0.34, p<.01. CONCLUSIÓN: El acondicionamiento es un mejor predictor de obesidad que la AF en esta muestra.

  17. The Effectiveness of a Pre-Exercise Performance Drink (PRX on Indices of Maximal Cardiorespiratory Fitness

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    Greenwood Lori

    2006-06-01

    Full Text Available Abstract This study examined the effectiveness of a pre-exercise drink (PRX called EM·PACT on indices of maximal cardiorespiratory fitness. Twenty-four males (n = 12 and females (n = 12 ages 18–24 years (20.25 + 1.42, volunteered as subjects. Each subject performed two randomized trials of a VO2max treadmill test within a week of each other. Subjects in this randomized, placebo controlled, counter balanced, crossover design, ingested either a placebo (water or PRX 20 minutes before each exercise bout. VO2max and time to exhaustion (Time during graded exercise testing were evaluated. Using paired samples t-tests, significantly greater mean values were found in VO2max and Time for the PRX trial compared to the placebo trial (p 2max and Time are enhanced by ingestion of PRX prior to exercise testing. The combined results of this investigation may provide meaningful practical applications for coaches and athletes alike regarding ergogenic hydration options.

  18. Physical activity, Cardio-Respiratory Fitness, and Metabolic Traits in Rural Mexican Tarahumara

    DEFF Research Database (Denmark)

    Christensen, Dirk Lund; Alcala-Sanchez, Imelda; Leal-Berumen, Irene;

    2012-01-01

    Objectives: To study the association between physical activity energy expenditure (PAEE) and cardio-respiratory fitness (CRF) with key metabolic traits and anthropometric measures in the Tarahumara of Mexico. Methods: A cross-sectional study was carried out in five rural communities in Chihuahua......, Me´xico including 64 adult Tarahumara, mean (SD) age 40.7 (12.9) years. Using a combined accelerometer and heart rate sensor, PAEE was measured over three consecutive days and nights and a sub-maximal step test was carried out in order to (1) calibrate heart rate at the individual level and (2...... and diastolic BP was 122 (20.8) and 82 (14.8) mm Hg, respectively, with 28.1% having hypertension. Mean body mass index was 27.5 (4.2) kg m22, with 71.9% being overweight. Following adjustment for age and sex, weak inverse associations were observed between PAEE and systolic BP (b 5 20.20, P 5 0...

  19. The Relationship between Serum 25-Hydroxyvitamin D Concentration, Cardiorespiratory Fitness, and Insulin Resistance in Japanese Men

    Directory of Open Access Journals (Sweden)

    Xiaomin Sun

    2014-12-01

    Full Text Available Here, we aim to investigate the independent and combined associations of serum 25-hydroxyvitamin D (25(OHD and cardiorespiratory fitness (CRF with glucose metabolism. Fasting blood samples of 107 men aged 40–79 years were analyzed for 25(OHD, glucose, insulin, glycated hemoglobin, and lipid profile. Homeostasis model assessment of insulin resistance index (HOMA-IR was calculated from the fasting concentrations of glucose and insulin. Visceral fat area (VFA was determined by magnetic resonance imaging and CRF by measuring maximal oxygen uptake. Median 25(OHD concentration was 36.3 nmol/L, while the prevalence of 25(OHD deficiency was 74.8%. Participants with high CRF had significantly lower HOMA-IR, glycated hemoglobin, and insulin values than participants with low CRF (p < 0.05. Higher 25(OHD concentration was strongly correlated with lower HOMA-IR and insulin values independent of VFA (p < 0.01 but significantly affected by CRF. In the high CRF group, participants with higher 25(OHD concentration had lower HOMA-IR values than participants with low 25(OHD concentration (p < 0.05. Higher 25(OHD and CRF are crucial for reducing insulin resistance regardless of abdominal fat. In addition, higher 25(OHD concentration may strengthen the effect of CRF on reducing insulin resistance in middle-aged and elderly Japanese men with high CRF.

  20. The effect of cardiorespiratory fitness, metabolic syndrome and cerebro-cardiovascular disease on cognition in older adults.

    OpenAIRE

    Bjøralt, Stine

    2014-01-01

    Background: Numerous studies have reported on the positive influence of superior physical health on the preservation of cognitive functions as we age. For ekxample, serveral exercise interventions of varying lengths aiming at increasing cardiorespiratory fitness in elderly populations have shown better preservation of brain structures and associated  cognitive functions. Other helath factors commonly know to affect cognition in old age are metabolic syndrome ( MetS) and various cardiovascular...

  1. Cardiorespiratory fitness and digestive cancer mortality: findings from the aerobics center longitudinal study.

    Science.gov (United States)

    Peel, J Brent; Sui, Xuemei; Matthews, Charles E; Adams, Swann A; Hébert, James R; Hardin, James W; Church, Timothy S; Blair, Steven N

    2009-04-01

    Although higher levels of physical activity are inversely associated with risk of colon cancer, few prospective studies have evaluated overall digestive system cancer mortality in relation to cardiorespiratory fitness (CRF). The authors examined this association among 38,801 men ages 20 to 88 years who performed a maximal treadmill exercise test at baseline in the Aerobics Center Longitudinal Study (Dallas, TX) during 1974 to 2003. Mortality was assessed over 29 years of follow-up (1974-2003). Two hundred eighty-three digestive system cancer deaths occurred during a mean 17 years of observation. Age-adjusted mortality rates per 10,000 person-years according to low, moderate, and high CRF groups were 6.8, 4.0, and 3.3 for digestive system cancer (P(trend) < 0.001). After adjustment for age, examination year, body mass index, smoking, drinking, family history of cancer, personal history of diabetes, hazard ratios (95% confidence intervals) for overall digestive cancer deaths for those in the middle and upper 40% of the distribution of CRF relative to those in the lowest 20% were 0.66 (0.49-0.88) and 0.56 (0.40-0.80), respectively. Being fit (the upper 80% of CRF) was associated with a lower risk of mortality from colon [0.61 (0.37-1.00)], colorectal [0.58 (0.37-0.92)], and liver cancer [0.28 (0.11-0.72)] compared with being unfit (the lowest 20% of CRF). These findings support a protective role of CRF against total digestive tract, colorectal, and liver cancer deaths in men. PMID:19293313

  2. Cardiorespiratory fitness and digestive cancer mortality: findings from the Aerobics Center Longitudinal Study (ACLS)

    Science.gov (United States)

    Peel, J. Brent; Sui, Xuemei; Matthews, Charles E.; Adams, Swann A.; Hébert, James R.; Hardin, James W.; Church, Timothy S.; Blair, Steven N.

    2009-01-01

    Although higher levels of physical activity are inversely associated with risk of colon cancer, few prospective studies have evaluated overall digestive system cancer mortality in relation to cardiorespiratory fitness (CRF). The authors examined this association among 38,801 men aged 20−88 years and who performed a maximal treadmill exercise test at baseline in the Aerobics Center Longitudinal Study (Dallas, Texas) during 1974−2003. Mortality was assessed over 29 years of follow-up (1974−2003). 283 digestive system cancer deaths occurred during a mean 17-year of observation. Age-adjusted mortality rates per 10,000 person-yrs according to low, moderate, and high CRF groups were 6.8, 4.0, and 3.3 for digestive system cancer (trend p < 0.001). After adjustment for age, examination year, body mass index, smoking, drinking, family history of cancer, personal history of diabetes, hazard ratios for overall digestive cancer deaths (95% confidence interval) for those in the middle and upper 40% of the distribution of CRF relative to those in the lowest 20% were 0.66 (0.49, 0.88) and 0.56 (0.40, 0.80), respectively. Being fit (the upper 80% of CRF) was associated with a lower risk of mortality from colon (0.61 [0.37, 1.00]), colorectal (0.58 [0.37, 0.92]), and liver cancer (0.28 [0.11, 0.72]), compared with being unfit (the lowest 20% of CRF). These findings support a protective role of CRF against total digestive tract, colorectal, and liver cancer deaths in men. PMID:19293313

  3. Associations of birth size and duration of breast feeding with cardiorespiratory fitness in childhood: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)

    International Nuclear Information System (INIS)

    Objectives: To explore the developmental origins of cardiorespiratory fitness. Methods: We examined the associations of birth size and duration of breast feeding with cardiorespiratory fitness assessed at the 9 year follow-up examination in 3612 participants of the Avon Longitudinal Study of Parents and Children (ALSPAC). We used physical work capacity at a heart rate of 170 beats per minute (PWC170) as our assessment of cardiorespiratory fitness. This was estimated using standard regression methods from parameters measured using an electronically braked cycle ergometer. Results: Birth weight, length and ponderal index were all positively associated with cardiorespiratory fitness in both sexes, with no strong evidence of a difference in effect between girls and boys. Work capacity increased by 1.12 W (95% CI: 0.83, 1.40) on average per 1 standard deviation (SD) greater birth weight. This association was not affected by adjustment for socioeconomic position and maternal smoking during pregnancy; there was some attenuation with adjustment for both maternal and paternal height and body mass index and more marked attenuation with adjustment for the child's height and body mass index. In the fully adjusted model work capacity increased by 0.51 W (95% CI: 0.21, 0.81) per SD birth weight. Whether an individual had been breastfed and duration of breastfeeding were not associated with cardiorespiratory fitness in any models. Conclusion: Our results provide some support for a role of intrauterine factors in determining cardiorespiratory fitness in childhood

  4. The association between cardiorespiratory fitness and abdominal adiposity in postmenopausal, physically inactive South Asian women

    Directory of Open Access Journals (Sweden)

    I.A. Lesser

    2015-01-01

    Full Text Available In South Asians, a unique obesity phenotype of high abdominal fat is associated with increased cardiovascular risk. Low cardiorespiratory fitness (CRF is associated with abdominal fat and an increased risk of cardiovascular disease. The purpose of this paper is to determine whether CRF as assessed by VO2 peak, in post-menopausal South Asian women, was associated with body fat distribution and abdominal fat. Physically inactive post-menopausal South Asian women (n = 55 from the Greater Vancouver area were recruited and assessed from January to August 2014. At baseline, VO2 peak was measured with the Bruce Protocol, abdominal fat with CT imaging, and body composition with dual energy X-ray absorptiometry. ANOVA was used to assess differences in subcutaneous abdominal adipose tissue (SAAT, visceral adipose tissue (VAT and total abdominal adipose tissue (TAAT between tertiles of CRF. Bivariate correlation and multiple linear regression analyses explored the association between VO2 peak with SAAT, VAT, TAAT and body composition. Models were further adjusted for body fat and body mass index (BMI. Compared to women in the lowest tertile of VO2 peak (13.8–21.8 mL/kg/min, women in the highest tertile (25.0–27.7 mL/kg/min had significantly lower waist circumference, BMI, total body fat, body fat percentage, lean mass, SAAT, VAT and TAAT (p < 0.05. We found VO2 peak to be negatively associated with SAAT, VAT and TAAT, independent of age and body fatness but not independent of BMI. Further research is necessary to assess whether exercise and therefore improvements in CRF would alter SAAT, VAT and TAAT in post-menopausal South Asian women.

  5. Endothelial wall thickness, cardiorespiratory fitness and inflammatory markers in obese and non-obese adolescents

    Directory of Open Access Journals (Sweden)

    Larissa R. Silva

    2014-03-01

    Full Text Available Background: Increased carotid intima-media thickness (c-IMT is considered a marker of early-onset atherosclerosis and it has been found in obese children and adolescents, but the risk factors associated with this population remain to be elucidated. Objective : To compare and verify the relationship between c-IMT, metabolic profile, inflammatory markers, and cardiorespiratory fitness in obese and non-obese children and adolescents. Method : Thirty-five obese subjects (19 boys and 18 non-obese subjects (9 boys, aged 10-16 years, were included. Anthropometry, body composition, blood pressure, maximal oxygen consumption (VO2max, and basal metabolic rate were evaluated. Serum glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR, blood lipids, C-reactive protein (CRP, and adiponectin were assessed. c-IMT was measured by ultrasound. Results: The results showed that c-IMT, triglycerides, insulin, HOMA-IR, and CRP values were significantly higher in the obese group than in the non-obese group, and high-density lipoprotein cholesterol (HDL-c, adiponectin, and VO2max values were significantly lower in the obese group than in the non-obese group. The c-IMT was directly correlated with body weight, waist circumference, % body fat, and HOMA-IR and inversely correlated with % free fat mass, HDL-c, and VO2max. Conclusions : Our findings show that c-IMT correlates not only with body composition, lipids, insulin resistance, and inflammation but also with low VO2max values in children and adolescents.

  6. Determinants of Racial/Ethnic Differences in Cardiorespiratory Fitness (from the Dallas Heart Study).

    Science.gov (United States)

    Pandey, Ambarish; Park, Bryan D; Ayers, Colby; Das, Sandeep R; Lakoski, Susan; Matulevicius, Susan; de Lemos, James A; Berry, Jarett D

    2016-08-15

    Previous studies have demonstrated ethnic/racial differences in cardiorespiratory fitness (CRF). However, the relative contributions of body mass index (BMI), lifestyle behaviors, socioeconomic status (SES), cardiovascular (CV) risk factors, and cardiac function to these differences in CRF are unclear. In this study, we included 2,617 Dallas Heart Study participants (58.6% women, 48.6% black; 15.7% Hispanic) without CV disease who underwent estimation of CRF using a submaximal exercise test. We constructed multivariable-adjusted linear regression models to determine the association between race/ethnicity and CRF, which was defined as peak oxygen uptake (ml/kg/min). Black participants had the lowest CRF (blacks: 26.3 ± 10.2; whites: 29.0 ± 9.8; Hispanics: 29.1 ± 10.0 ml/kg/min). In multivariate analysis, both black and Hispanic participants had lower CRF after adjustment for age and gender (blacks: Std β = -0.15; p value ≤0.0001, Hispanics: Std β = -0.05, p value = 0.01; ref group: whites). However, this association was considerably attenuated for black (Std β = -0.04, p value = 0.03) and no longer significant for Hispanic ethnicity (p value = 0.56) after additional adjustment for BMI, lifestyle factors, SES, and CV risk factors. Additional adjustment for stroke volume did not substantially change the association between black race/ethnicity and CRF (Std β = -0.06, p value = 0.01). In conclusion, BMI, lifestyle, SES, and traditional risk factor burden are important determinants of ethnicity-based differences in CRF. PMID:27349903

  7. Associations of cardiorespiratory fitness, physical activity, and adiposity with arterial stiffness in children.

    Science.gov (United States)

    Veijalainen, A; Tompuri, T; Haapala, E A; Viitasalo, A; Lintu, N; Väistö, J; Laitinen, T; Lindi, V; Lakka, T A

    2016-08-01

    Associations of cardiorespiratory fitness (CRF), physical activity (PA), sedentary behavior, and body fat percentage (BF%) with arterial stiffness and dilation capacity were investigated in 160 prepubertal children (83 girls) 6-8 years of age. We assessed CRF (watts/lean mass) by maximal cycle ergometer exercise test, total PA, structured exercise, unstructured PA, commuting to and from school, recess PA and total and screen-based sedentary behavior by questionnaire, BF% using dual-energy X-ray absorptiometry, and arterial stiffness and dilation capacity using pulse contour analysis. Data were adjusted for sex and age. Poorer CRF (standardized regression coefficient β = -0.297, P < 0.001), lower unstructured PA (β = -0.162, P = 0.042), and higher BF% (β = 0.176, P = 0.044) were related to higher arterial stiffness. When CRF, unstructured PA, and BF% were in the same model, only CRF was associated with arterial stiffness (β = -0.246, P = 0.006). Poorer CRF was also related to lower arterial dilation capacity (β = 0.316, P < 0.001). Children with low CRF (< median) and high BF% (≥ median; P = 0.002), low CRF and low unstructured PA (< median; P = 0.006) or children with low unstructured PA and high BF% (P = 0.005) had higher arterial stiffness than children in the opposite halves of these variables. Poor CRF was independently associated with increased arterial stiffness and impaired arterial dilation capacity among children. PMID:26220100

  8. A Simple Step Test to Estimate Cardio-Respiratory Fitness Levels of Rheumatoid Arthritis Patients in a Clinical Setting

    Directory of Open Access Journals (Sweden)

    Jennifer K. Cooney

    2013-01-01

    Full Text Available Purpose. Exercise tests represent an important clinical tool to evaluate cardio-respiratory fitness and to predict future adverse cardiovascular events. However, use of such tests in patients with rheumatoid arthritis (RA is relatively uncommon despite well-established evidence that low exercise capacity and high CVD mortality are features of this disease. Therefore, this study examined the validity and reliability of a sub-maximal step test for use in RA patients. Methods. Thirty patients (24 females (mean ± SD age 53±10 years performed a sub-maximal step test on two occasions to estimate the criterion measure of cardio-respiratory fitness (V.O2max. A further maximal cycling test provided a direct fitness measurement (V.O2 peak. Pearson correlation coefficient, intraclass correlation coefficient (ICC, Bland and Altman plots, and 95% limits of agreement (LOA were used to determine the validity and reliability of the sub-maximal test. Results. Estimated V.O2max correlated well with directly measured V.O2 peak (r=0.79, LoA ±5.7 mL·kg−1·min−1. Test-retest reproducibility for estimated V.O2max was excellent (ICC=0.97, LoA ±2.2 mL·kg−1·min−1. Conclusion. The sub-maximal step test studied here represents a valid and reproducible method to estimate cardio-respiratory fitness in RA patients. This test may be useful for the assessment and management of CVD risk in a clinical setting.

  9. Cardiorespiratory Fitness Is Associated with Executive Control in Late-Middle-Aged Adults: An Event-Related (De) Synchronization (ERD/ERS) Study

    Science.gov (United States)

    Chu, Chien-Heng; Yang, Kao-Teng; Song, Tai-Fen; Liu, Jen-Hao; Hung, Tsung-Min; Chang, Yu-Kai

    2016-01-01

    The present study sought to determine whether cardiorespiratory fitness is associated with cognitive function in late-middle-aged adults from event-related desynchronization (ERD) and event-related synchronization (ERS) perspectives. Late-middle-aged adults were categorized into either the high-fitness group or the low-fitness group based on their estimated cardiorespiratory fitness values. The participants completed the Stroop Test, which is comprised of incongruent and neutral conditions, while the brain activities were recoded. The alpha ERD and ERS values based on the equation proposed by Pfurtscheller (1977) were further calculated. The results revealed that the adults with higher levels of cardiorespiratory fitness demonstrated superior Stroop performance, regardless of Stroop congruency. While these high-fitness adults had less positive upper alpha ERD values in the later epoch window compared to their lower-fitness counterparts, they had greater lower alpha ERD values in the early epoch window. Additionally, in the late epoch window, the high-fitness adults showed less positive lower alpha ERD values on neutral, but not incongruent condition, relative to their low-fitness counterparts. These findings suggest that cardiorespiratory fitness of the late-middle-aged adults is positively associated with cognitive functioning, especially the cognitive processes related to the inhibition of task-irrelevant information and those processes required the devotion of greater amounts of attentional resources to a given task. PMID:27536259

  10. Comparison of two-hand kettlebell exercise and graded treadmill walking: effectiveness as a stimulus for cardiorespiratory fitness.

    Science.gov (United States)

    Thomas, James F; Larson, Kurtis L; Hollander, Daniel B; Kraemer, Robert R

    2014-04-01

    Prevailing interest in the use of kettlebell (KB) exercises for rehabilitation and improvement of muscular strength has led to several recent studies, some suggesting that KB exercise may be useful for improvement of cardiorespiratory fitness. The purpose of this study was to determine whether KB exercise would produce similar cardiovascular stress to that of walking and thus provide an additional exercise mode for the improvement of cardiorespiratory fitness. It was hypothesized that a moderate-intensity, continuous KB protocol, would produce similar metabolic and cardiorespiratory responses as a brisk bout of graded treadmill (TM) walking, but greater rating of perceived exertion (RPE). Ten novice volunteers (5 men, 5 women) completed a preliminary session to determine body composition and VO2max and to familiarize participants with standardized KB exercise technique. Subsequently, they completed a 30-minute KB session that included 3 continuous 10-minute sets of 10 KB swings followed by 10 sumo deadlifts, with 3-minute rests between 10-minute exercise periods. The third session was a 30-minute TM regimen that began at the walking speed and 4% grade that matched the VO2 from the KB session and included 3-minute rest intervals after 10-minute TM exercise periods. VO2, respiratory exchange ratio, kcal·min, and blood pressure were similar for KB and moderate-intensity TM exercise, but RPE and heart rate were greater during KB exercise. Data indicate that a KB routine consisting of 2-hand swings and sumo deadlifts with 3-minute rest periods produces similar metabolic responses to those of a moderate-intensity TM walking protocol designed for the improvement of aerobic fitness. PMID:24345977

  11. Association of Adiposity, Cardiorespiratory Fitness and Exercise Practice with the Prevalence of Type 2 Diabetes in Brazilian Elderly Women

    Science.gov (United States)

    Krause, Maressa P.; Hallage, Tatiane; Gama, Mirnaluci Paulino Ribeiro; Goss, Fredric L.; Robertson, Robert; da Silva, Sergio G.

    2007-01-01

    Background: Diabetes incidence in people with advanced age is increasing at an alarming rate, and for this reason the screening of high-risk individuals such as elderly women is critically important. Objective: To analyze the association of adiposity, cardiorespiratory fitness and exercise practice with type 2 diabetes (T2D) in elderly Brazilian women. Methods: Participated of this cross sectional study 1,059 elderly women (mean 69.5 yr; SD 6.1), who self-reported family history of cardiovascular disease, smoking status, hypertension, and T2D diagnosed previously by a physician. The following independent variables were assessed: exercise practice, body mass index, waist circumference, and cardiorespiratory fitness. Logistic regression analysis was used to investigate the association between each independent variable with T2D using adjusted-models. Results: T2D prevalence was 16%. General and central adiposity were directly associated with T2D, whereas cardiorespiratory fitness was inversely related with T2D. The joint effect of exercise practice and central adiposity showed that inactive women had higher odds ratio for T2D when compared with active ones, within the same WC group. Inactive women with WC ≥ 94.0 cm had an odds ratio of 5.8 (95%IC 1.3-25.3). Conclusions: A direct positive association was found between general and central adiposity, as well as an inverse relation between CRF and exercise practice with T2D. Elderly women who practice exercise regularly had lower odds for T2D. Health professionals should encourage individuals of all ages to engage on regular exercise practice, which could reduce body fatness and may be beneficial in reducing the prevalence of T2D in older ages. PMID:18071583

  12. Association of Adiposity, Cardiorespiratory Fitness and Exercise Practice with the Prevalence of Type 2 Diabetes in Brazilian Elderly Women

    Directory of Open Access Journals (Sweden)

    Maressa P. Krause, Tatiane Hallage, Mirnaluci Paulino Ribeiro Gama, Fredric L. Goss, Robert Robertson, Sergio G. da Silva

    2007-01-01

    Full Text Available Background: Diabetes incidence in people with advanced age is increasing at an alarming rate, and for this reason the screening of high-risk individuals such as elderly women is critically important. Objective: To analyze the association of adiposity, cardiorespiratory fitness and exercise practice with type 2 diabetes (T2D in elderly Brazilian women. Methods: Participated of this cross sectional study 1,059 elderly women (mean 69.5 yr; SD 6.1, who self-reported family history of cardiovascular disease, smoking status, hypertension, and T2D diagnosed previously by a physician. The following independent variables were assessed: exercise practice, body mass index, waist circumference, and cardiorespiratory fitness. Logistic regression analysis was used to investigate the association between each independent variable with T2D using adjusted-models. Results: T2D prevalence was 16%. General and central adiposity were directly associated with T2D, whereas cardiorespiratory fitness was inversely related with T2D. The joint effect of exercise practice and central adiposity showed that inactive women had higher odds ratio for T2D when compared with active ones, within the same WC group. Inactive women with WC ≥ 94.0 cm had an odds ratio of 5.8 (95%IC 1.3-25.3. Conclusions: A direct positive association was found between general and central adiposity, as well as an inverse relation between CRF and exercise practice with T2D. Elderly women who practice exercise regularly had lower odds for T2D. Health professionals should encourage individuals of all ages to engage on regular exercise practice, which could reduce body fatness and may be beneficial in reducing the prevalence of T2D in older ages.

  13. Decreased physical activity and cardiorespiratory fitness in adults with ankylosing spondylitis: a cross-sectional controlled study.

    Science.gov (United States)

    O'Dwyer, Tom; O'Shea, Finbar; Wilson, Fiona

    2015-11-01

    The health benefits of physical activity (PA) in the general population are numerous; however, few studies have measured PA among adults with ankylosing spondylitis (AS). The aims of this study were to: (1) objectively measure the PA levels and cardiorespiratory fitness of adults with AS and compare these to population controls, and (2) examine the relationships between PA, cardiorespiratory function and condition-specific outcomes. This cross-sectional study included participants (>18 years) meeting the modified New York criteria for AS, and matched population controls. Exclusion criteria were the presence of comorbidities limiting PA, or recent changes in medication usage. Participants completed clinical questionnaires assessing disease activity, physical function and quality of life. Tri-axial accelerometers recorded habitual PA over 1 week. Cardiorespiratory fitness was assessed by submaximal treadmill test with breath-by-breath gas analysis and heart rate monitoring. Thirty-nine adults with AS and 39 controls were recruited. The AS group spent significantly less time performing vigorous-intensity PA than controls [mean difference (95 % CI) 1.8 min/day (1.2-2.7)] and performed significantly fewer bouts of health-enhancing PA [1.7 min/day (1.1-2.5)]. The AS group had significantly lower predicted VO(2MAX) than controls [6.0 mL kg(-1) min(-1) (1.8-10.1)]. PA was associated with aerobic capacity. Sedentary time was associated with disease activity and physical function. Adults with AS participate in less health-enhancing PA than population controls. Fewer than half meet PA recommendations, despite exercise being a key component of AS management. Explorations of PA behaviour and strategies to increase PA participation are needed.

  14. Relationships between anthropometry, cardiorespiratory fitness indices and physical activity levels in different age and sex groups in rural Senegal (West Africa)

    OpenAIRE

    Bénéfice, Eric; Mbaye Ndiaye, Gnagna

    2005-01-01

    BACKGROUND: A high level of activity is commonplace in traditional subsistence societies. Physiological characteristics of individuals, including body composition and physical fitness, could be limiting factors when performing daily tasks. OBJECTIVES: The study investigated the relationships between cardiorespiratory fitness, nutritional status and physical activity patterns, so as to test the hypothesis that these relationships are less straightforward in children than in adults. STUDY DESIG...

  15. Influence of cardiorespiratory fitness and physical activity levels on cardiometabolic risk factors during menopause transition: A MONET study.

    Science.gov (United States)

    Abdulnour, Joseph; Razmjou, Sahar; Doucet, Éric; Boulay, Pierre; Brochu, Martin; Rabasa-Lhoret, Rémi; Lavoie, Jean-Marc; Prud'homme, Denis

    2016-12-01

    To determine the influence of cardiorespiratory fitness (hereafter "fitness") and physical activity levels on cardiometabolic risk factors in premenopausal women going through the menopause transition. An ancillary study including 66 premenopausal women who participated to a 5-year observational, longitudinal study (2004 to 2009 in Ottawa) on the effects of menopause transition on body composition and cardiometabolic risk factors. Women underwent a graded exercise test on treadmill to measure peak oxygen uptake (VO2 peak) at year 1 and 5 and physical activity levels were measured using accelerometers. Cardiometabolic risk factors included: waist circumference, fasting plasma lipids, glucose and insulin levels, HOMA-IR score, c-reactive protein, apolipoprotein B (apoB) and resting systolic and diastolic blood pressure. Change in fitness was not associated with changes in cardiometabolic risk factors. The changes in total physical activity levels on the other hand showed a significant negative association with apoB levels. Three-way linear mixed model repeated measures, showed lower values of waist circumference, fasting triglycerides, insulin levels, HOMA-IR score, apoB and diastolic blood pressure in women with a fitness ≥ 30.0 mlO2 kg(- 1) min(- 1) compared to women with a fitness fitness and physical activity levels, fitness was associated with more favorable values of cardiometabolic risk factors in women followed for 5 years during the menopause transition. PMID:27453812

  16. Influence of cardiorespiratory fitness and physical activity levels on cardiometabolic risk factors during menopause transition: A MONET study.

    Science.gov (United States)

    Abdulnour, Joseph; Razmjou, Sahar; Doucet, Éric; Boulay, Pierre; Brochu, Martin; Rabasa-Lhoret, Rémi; Lavoie, Jean-Marc; Prud'homme, Denis

    2016-12-01

    To determine the influence of cardiorespiratory fitness (hereafter "fitness") and physical activity levels on cardiometabolic risk factors in premenopausal women going through the menopause transition. An ancillary study including 66 premenopausal women who participated to a 5-year observational, longitudinal study (2004 to 2009 in Ottawa) on the effects of menopause transition on body composition and cardiometabolic risk factors. Women underwent a graded exercise test on treadmill to measure peak oxygen uptake (VO2 peak) at year 1 and 5 and physical activity levels were measured using accelerometers. Cardiometabolic risk factors included: waist circumference, fasting plasma lipids, glucose and insulin levels, HOMA-IR score, c-reactive protein, apolipoprotein B (apoB) and resting systolic and diastolic blood pressure. Change in fitness was not associated with changes in cardiometabolic risk factors. The changes in total physical activity levels on the other hand showed a significant negative association with apoB levels. Three-way linear mixed model repeated measures, showed lower values of waist circumference, fasting triglycerides, insulin levels, HOMA-IR score, apoB and diastolic blood pressure in women with a fitness ≥ 30.0 mlO2 kg(- 1) min(- 1) compared to women with a fitness fitness and physical activity levels, fitness was associated with more favorable values of cardiometabolic risk factors in women followed for 5 years during the menopause transition.

  17. The effects of cardiorespiratory fitness and acute aerobic exercise on executive functioning and EEG entropy in adolescents

    Directory of Open Access Journals (Sweden)

    Michael John Hogan

    2015-10-01

    Full Text Available The current study examined the effects of cardiorespiratory fitness, identified with a continuous graded cycle ergometry, and aerobic exercise on cognitive functioning and entropy of the electroencephalogram (EEG in 30 adolescents between the ages of 13 and 14 years. Higher and lower fit participants performed an executive function task after a bout of acute exercise and after rest while watching a film. EEG entropy, using the sample entropy measure, was repeatedly measured during the 1500ms post-stimulus interval to evaluate changes in entropy over time. Analysis of the behavioural data for lower and higher fit groups revealed an interaction between fitness levels and acute physical exercise. Notably, lower fit, but not higher fit, participants had higher error rates for NoGo relative to Go trials in the rest condition, whereas in the acute exercise condition there were no differences in error rates between groups; higher fit participants also had significantly faster reaction times in the exercise condition in comparison with the rest condition. Analysis of EEG data revealed that higher fit participants demonstrated lower entropy post-stimulus than lower fit participants in the left frontal hemisphere, possibly indicating increased efficiency of early stage stimulus processing and more efficient allocation of cognitive resources to the task demands. The results suggest that EEG entropy is sensitive to stimulus processing demands and varies as a function of physical fitness levels, but not acute exercise. Physical fitness, in turn, may enhance cognition in adolescence by facilitating higher functionality of the attentional system in the context of lower levels of frontal EEG entropy.

  18. The intestinal microbiome and skeletal fitness: Connecting bugs and bones.

    Science.gov (United States)

    Charles, Julia F; Ermann, Joerg; Aliprantis, Antonios O

    2015-08-01

    Recent advances have dramatically increased our understanding of how organ systems interact. This has been especially true for immunology and bone biology, where the term "osteoimmunology" was coined to capture this relationship. The importance of the microbiome to the immune system has also emerged as a driver of health and disease. It makes sense therefore to ask the question: how does the intestinal microbiome influence bone biology and does dysbiosis promote bone disease? Surprisingly, few studies have analyzed this connection. A broader interpretation of this question reveals many mechanisms whereby the microbiome may affect bone cells. These include effects of the microbiome on immune cells, including myeloid progenitors and Th17 cells, as well as steroid hormones, fatty acids, serotonin and vitamin D. As mechanistic interactions of the microbiome and skeletal system are revealed within and without the immune system, novel strategies to optimize skeletal fitness may emerge. PMID:25840106

  19. Periodontal infection and cardiorespiratory fitness in younger adults: results from continuous national health and nutrition examination survey 1999-2004.

    Directory of Open Access Journals (Sweden)

    Ashley Thai

    Full Text Available OBJECTIVE: Previous studies report associations between periodontal infection and cardiorespiratory fitness but no study has examined the association among younger adults. Our objective was to study the association between clinical measures of periodontal infection and cardiorespiratory fitness levels among a population-based sample of younger adults. METHODS: The Continuous National Health and Nutrition Examination Survey 1999-2004 enrolled 2,863 participants (46% women who received a partial-mouth periodontal examination and completed a submaximal treadmill test for the assessment of estimated VO2 max(eVO2 max . Participants were mean±SD age 33±9 years (range = 20-49 years, 30% Hispanic, 48% White, 19% Black, and 3% other. Mean eVO2 max (mL/kg/minute as well as eVO2 max≤32 mL/kg/minute (20th percentile were regressed across quartiles of mean probing depth and mean attachment loss in multivariable linear and logistic regression models. RESULTS: After multivariable adjustment, mean eVO2 max levels±SE across quartiles of attachment loss were 39.72±0.37, 39.64±0.34, 39.59±0.36, and 39.85±0.39 (P = 0.99. Mean eVO2 max±SE across quartiles of probing depth were 39.57±0.32, 39.78±0.38, 39.19±0.25, and 40.37±0.53 (P = 0.28. Similarly, multivariable adjusted mean eVO2 max values were similar between healthy participants vs. those with moderate/severe periodontitis: 39.70±0.21 vs. 39.70±0.90 (P = 1.00. The odds ratio (OR for low eVO2 max comparing highest vs. lowest quartile of attachment loss = 0.89[95% CI 0.64-1.24]. The OR for comparing highest vs. lowest probing depth quartile = 0.77[95% CI 0.51-1.15]. CONCLUSION: Clinical measures of periodontal infection were not related to cardiorespiratory fitness in a sample of generally healthy younger adults.

  20. Effects of Cardiorespiratory Fitness and Obesity on Salivary Secretory IgA and Alpha-Amylase in South African Children.

    Science.gov (United States)

    Starzak, Dorota E; Konkol, Kristen F; McKune, Andrew J

    2016-01-01

    This study examined whether cardiorespiratory fitness (CRF) and body composition are associated with salivary secretory immunoglobulin A (SIgA), a mucosal immunity marker, and salivary alpha-amylase (sAA), a marker of stress-related sympathetic nervous system (SNS) activity, in South African children. Morning (7:30-8:00 a.m.) saliva samples were collected from 132 children (10.05 ± 1.68 years old, 74 females, 58 males). Body composition, resting blood pressure, and predicted maximal aerobic capacity (VO2max) were determined, and SIgA and sAA were quantified. Obese children had significantly higher sAA compared with overweight and normal weight children (p mitigator. Age and BMI predicted SIgA secretion rate (p mitigated sympathetic activation was not associated with mucosal immunity. PMID:27483329

  1. Limited Effects of a 2-Year School-Based Physical Activity Intervention on Body Composition and Cardiorespiratory Fitness in 7-Year-Old Children

    Science.gov (United States)

    Magnusson, Kristjan Thor; Hrafnkelsson, Hannes; Sigurgeirsson, Ingvar; Johannsson, Erlingur; Sveinsson, Thorarinn

    2012-01-01

    The aim of this study was to assess the effects of a 2-year cluster-randomized physical activity and dietary intervention program among 7-year-old (at baseline) elementary school participants on body composition and objectively measured cardiorespiratory fitness. Three pairs of schools were selected and matched, then randomly selected as either an…

  2. Associations between Objectively Measured Physical Activity, Cardiorespiratory Fitness and Risk Factors for Metabolic Syndrome in 12- to 15-Year-Old Tianjin City Children

    Science.gov (United States)

    Tan, Sijie; Wang, Jianxiong; Zhang, Yibing; Zhang, Chen

    2015-01-01

    Objective: The study aim was to explore associations between daily physical activity level, cardiorespiratory fitness and metabolic syndrome among Chinese children. Design: We conducted a school-based, cross-sectional study. Setting: Participants including 112 boys and 121 girls were recruited from three schools in the urban suburbs of Tianjin…

  3. Exercise therapy, cardiorespiratory fitness and their effect on brain volumes: a randomised controlled trial in patients with schizophrenia and healthy controls.

    Science.gov (United States)

    Scheewe, Thomas W; van Haren, Neeltje E M; Sarkisyan, Gayane; Schnack, Hugo G; Brouwer, Rachel M; de Glint, Maria; Hulshoff Pol, Hilleke E; Backx, Frank J G; Kahn, René S; Cahn, Wiepke

    2013-07-01

    The objective of this study was to examine exercise effects on global brain volume, hippocampal volume, and cortical thickness in schizophrenia patients and healthy controls. Irrespective of diagnosis and intervention, associations between brain changes and cardiorespiratory fitness improvement were examined. Sixty-three schizophrenia patients and fifty-five healthy controls participated in this randomised controlled trial. Global brain volumes, hippocampal volume, and cortical thickness were estimated from 3-Tesla MRI scans. Cardiorespiratory fitness was assessed with a cardiopulmonary ergometer test. Subjects were assigned exercise therapy or occupational therapy (patients) and exercise therapy or life-as-usual (healthy controls) for six months 2h weekly. Exercise therapy effects were analysed for subjects who were compliant at least 50% of sessions offered. Significantly smaller baseline cerebral (grey) matter, and larger third ventricle volumes, and thinner cortex in most areas of the brain were found in patients versus controls. Exercise therapy did not affect global brain and hippocampal volume or cortical thickness in patients and controls. Cardiorespiratory fitness improvement was related to increased cerebral matter volume and lateral and third ventricle volume decrease in patients and to thickening in the left hemisphere in large areas of the frontal, temporal and cingulate cortex irrespective of diagnosis. One to 2h of exercise therapy did not elicit significant brain volume changes in patients or controls. However, cardiorespiratory fitness improvement attenuated brain volume changes in schizophrenia patients and increased thickness in large areas of the left cortex in both schizophrenia patients and healthy controls. PMID:22981376

  4. Influence of taekwondo as security martial arts training on anaerobic threshold, cardiorespiratory fitness, and blood lactate recovery.

    Science.gov (United States)

    Kim, Dae-Young; Seo, Byoung-Do; Choi, Pan-Am

    2014-04-01

    [Purpose] This study was conducted to determine the influence of Taekwondo as security martial arts training on anaerobic threshold, cardiorespiratory fitness, and blood lactate recovery. [Subjects and Methods] Fourteen healthy university students were recruited and divided into an exercise group and a control group (n = 7 in each group). The subjects who participated in the experiment were subjected to an exercise loading test in which anaerobic threshold, value of ventilation, oxygen uptake, maximal oxygen uptake, heart rate, and maximal values of ventilation / heart rate were measured during the exercise, immediately after maximum exercise loading, and at 1, 3, 5, 10, and 15 min of recovery. [Results] At the anaerobic threshold time point, the exercise group showed a significantly longer time to reach anaerobic threshold. The exercise group showed significantly higher values for the time to reach VO2max, maximal values of ventilation, maximal oxygen uptake and maximal values of ventilation / heart rate. Significant changes were observed in the value of ventilation volumes at the 1- and 5-min recovery time points within the exercise group; oxygen uptake and maximal oxygen uptake were significantly different at the 5- and 10-min time points; heart rate was significantly different at the 1- and 3-min time points; and maximal values of ventilation / heart rate was significantly different at the 5-min time point. The exercise group showed significant decreases in blood lactate levels at the 15- and 30-min recovery time points. [Conclusion] The study results revealed that Taekwondo as a security martial arts training increases the maximal oxygen uptake and anaerobic threshold and accelerates an individual's recovery to the normal state of cardiorespiratory fitness and blood lactate level. These results are expected to contribute to the execution of more effective security services in emergencies in which violence can occur.

  5. Cardiorespiratory fitness level correlates inversely with excess post-exercise oxygen consumption after aerobic-type interval training

    Directory of Open Access Journals (Sweden)

    Matsuo Tomoaki

    2012-11-01

    Full Text Available Abstract Background The purpose of this study was to reveal any association between cardiorespiratory fitness level and excess post-exercise oxygen consumption (EPOC using three cycling protocols with varying degrees of exercise intensity, i.e., sprint interval training (SIT, high-intensity interval aerobic training (HIAT, and continuous aerobic training (CAT. Findings Ten healthy men, aged 20 to 31 years, attended a cross-over experiment and completed three exercise sessions: SIT consisting of 7 sets of 30-s cycling at 120% VO2max with a 15-s rest between sets; HIAT consisting of 3 sets of 3-min cycling at 80~90% VO2max with a 2-min active rest at 50% VO2max between sets; and CAT consisting of 40 min of cycling at 60~65% VO2max. During each session, resting VO2, exercise VO2, and a 180-min post-exercise VO2 were measured. The net exercise VO2 during the SIT, HIAT, and CAT averaged 14.7 ± 1.5, 31.8 ± 4.1, and 71.1 ± 10.0 L, and the EPOCs averaged 6.8 ± 4.0, 4.5 ± 3.3, and 2.9 ± 2.8 L, respectively. The EPOC with SIT was greater than with CAT (P P = 0.12. Correlation coefficients obtained between subjects’ VO2max and the ratio of EPOC to net exercise VO2 for SIT, HIAT, and CAT were −0.61 (P = 0.06, -0.79 (P P = 0.23, respectively. Conclusions Our data suggest that cardiorespiratory fitness level correlates negatively with the magnitude of EPOC, especially when performing aerobic-type interval training.

  6. Home and Work Physical Activity Environments: Associations with Cardiorespiratory Fitness and Physical Activity Level in French Women

    Science.gov (United States)

    Oppert, Jean-Michel; Charles, Marie-Aline; Charreire, Hélène; Menai, Mehdi; De Bourdeaudhuij, Ilse; Brage, Soren; de Lauzon-Guillain, Blandine; Fagherazzi, Guy; Balkau, Beverley

    2016-01-01

    The influence of the physical activity environment in the home and at work on cardiorespiratory fitness (CRF) and objectively-measured physical activity has not been extensively studied. We recruited 147 women with a (mean ± SD) age of 54 ± 7 years and without evidence of chronic disease. The physical activity environment was assessed by self-report (Assessing Levels of PHysical Activity or ALPHA questionnaire), CRF using a submaximal step test, usual physical activity using combined heart rate and accelerometry, as well as by a validated questionnaire (Recent Physical Activity Questionnaire). Summary scores of the home environment and the work environment derived from the ALPHA questionnaire were positively correlated with CRF after adjustment for age (r = 0.18, p = 0.03 and r = 0.28, p < 0.01, respectively). Women owning a bicycle or having a garden (which may prompt physical activity) had higher CRF; those with a bicycle at home also had a higher physical activity energy expenditure. Similarly, women who had access to fitness equipment at work had higher CRF. In conclusion, these results provide new insights into potential environmental influences on physical capacity and physical activity that could inform the design of physical activity promotion strategies. PMID:27537900

  7. Improved cerebral oxygenation response and executive performance as a function of cardiorespiratory fitness in older women: a fNIRS study

    Directory of Open Access Journals (Sweden)

    Cédric T Albinet

    2014-10-01

    Full Text Available Cardiorespiratory fitness has been shown to protect and enhance cognitive and brain functions, but little is known about the cortical mechanisms that underlie these changes in older adults. In this study, functional NIRS was used to investigate variations in oxyhemoglobin ([HbO2] and in deoxyhemoglobin ([HHb] in the dorsolateral prefrontal cortex (DLPFC during the performance of an executive control task in older women with different levels of cardiorespiratory fitness (VO2max. Thirty-four women aged 60-77 years were classified as high-fit and low-fit based on VO2max measures. They all performed a control counting task and the Random Number Generation (RNG task at two different paces (1 number / 1 s and 1 number / 1.5 s, allowing to manipulate task difficulty, while hemodynamic responses in the bilateral DLPFCs were recorded using continuous-wave NIRS. The behavioral data revealed that the high-fit women showed significantly better performance on the RNG tasks compared with the low-fit women. The high-fit women showed significant increases in [HbO2] responses in both left and right DLPFCs during the RNG task, while the low-fit women showed significantly less activation in the right DLPFC compared with the right DLPFC of the high-fit women and compared with their own left DLPFC. At the level of the whole sample, increases in the [HbO2] responses in the right DLPFC were found to mediate in part the relationship between VO2max level and executive performance during the RNG task at 1.5 s but not at 1 s. These results provide support for the cardiorespiratory fitness hypothesis and suggest that higher levels of aerobic fitness in older women are related to increased cerebral oxygen supply to the DLPFC, sustaining better cognitive performance.

  8. The contribution of cardiorespiratory fitness and visceral fat to risk factors in Japanese patients with impaired glucose tolerance and type 2 diabetes mellitus.

    Science.gov (United States)

    Nagano, M; Kai, Y; Zou, B; Hatayama, T; Suwa, M; Sasaki, H; Kumagai, S

    2004-05-01

    It is still unclear as to how cardiorespiratory fitness and visceral fat accumulation contribute to coronary heart disease (CHD) risk factors in patients with diabetes mellitus. The purpose of the present study was to investigate whether cardiorespiratory fitness contributes to such risk factors independently of visceral fat accumulation. Two hundred Japanese patients (137 men and 63 women, aged 22 to 81 years) with impaired glucose tolerance (IGT) and type 2 diabetes mellitus (type 2 DM) without any intervention and pharmacological therapy participated in a cross-sectional study. The levels of fasting insulin, triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and resting blood pressure were assessed. Maximal oxygen uptake (V.o(2max)), an index of cardiorespiratory fitness, was predicted by a graded exercise test using a cycle ergometer. Visceral fat area (VFA) was measured by computed tomography scan. The criteria for abnormalities of the risk factors were determined according to the standard values for Japanese. All subjects were divided equally into the following 3 groups according to their fitness level: low-fit (V.o(2max) fit (32 fit (V.o(2max) > or = 36 in men, V.o(2max) > or = 30 in women). The association between fitness level and the prevalence of abnormal values for these parameters was analyzed by a multiple logistic regression model adjusted for age and VFA. The odds ratio (OR) and 95% confidence interval (CI) for the prevalence of hyperinsulinemia were significantly lower in the mid-fit (OR = 0.35, 95% CI, 0.16 to 0.78) and in the high-fit groups (OR = 0.40, 95% CI, 0.16 to 0.98) compared with the low-fit group. In addition, ORs for the prevalence of low HDL-C in the mid-fit and high-fit groups were significantly lower (OR = 0.35, 95% CI, 0.14 to 0.86; and OR = 0.19; 95% CI, 0.08 to 0.60, respectively) than in the low-fit group. These results suggested that cardiorespiratory fitness might be one of the predictors

  9. Fitness knowledge, cardiorespiratory endurance and body composition of high school students

    Directory of Open Access Journals (Sweden)

    Williams Skip M.

    2013-11-01

    Full Text Available Study aim: The purpose of this study was to determine if high school physical education seniors’ health-related fitness knowledge is related to their aerobic capacity and body composition.

  10. The challenge of preserving cardiorespiratory fitness in physically inactive patients with colon or breast cancer during adjuvant chemotherapy: a randomised feasibility study

    DEFF Research Database (Denmark)

    Møller, Tom; Lillelund, Christian; Andersen, Christina;

    2015-01-01

    in order to support cardio-respiratory fitness and lifestyle changes in an at-risk population of pre-illness physically inactive cancer patients.Methods Patients with breast or colon cancer referred to adjuvant chemotherapy and by the oncologists pre-screening verified as physically inactive were eligible...... instrument in order to correspond with cardio-respiratory fitness (VO2 peak) proved to be an applicable method to identify pre-illness physically inactive breast and colon cancer patients. The study demonstrated convincing recruitment (67%), safety and intervention adherence among breast cancer patients...... to enter a randomised three-armed feasibility study comparing a 12-week supervised hospital-based moderate to high intensity exercise intervention or alternate an instructive home-based12-week pedometer intervention, with usual care.Results Using a recommendation based physical activity screening...

  11. Sprint interval and sprint continuous training increases circulating CD34+ cells and cardio-respiratory fitness in young healthy women.

    Directory of Open Access Journals (Sweden)

    Emma Harris

    Full Text Available INTRODUCTION: The improvement of vascular health in the exercising limb can be attained by sprint interval training (SIT. However, the effects on systemic vascular function and on circulating angiogenic cells (CACs which may contribute to endothelial repair have not been investigated. Additionally, a comparison between SIT and sprint continuous training (SCT which is less time committing has not been made. METHODS: 12 women (22±2 yrs completed 12 sessions of either SIT (n = 6 or work-matched SCT (n = 6 on 3 days/week. Pre and post-training assessments included brachial artery endothelial function and peripheral blood analysis for CAC number (CD34+/CD34+CD45dim. CAC function was measured by migration and adhesion assays. Cardio-respiratory fitness, carotid arterial stiffness and carotid-radial and brachial-foot pulse wave velocity (PWV were also evaluated. RESULTS: CD34+ CACs increased following training in both groups but CD34+CD45dim did not (Pre CD34+: 40±21/105 leukocytes, Post CD34+: 56±24/105 leukocytes, main time effect p0.05. DISCUSSION: SCT involving little time commitment is comparable to SIT in increasing CD34+ cell number and [Formula: see text]. An increased mobilisation of CD34+ CACs suggests that sprint training may be an effective method to enhance vascular repair.

  12. Effects of Cardiorespiratory Fitness on Serum Ferritin Concentration and Incidence of Type 2 Diabetes: Evidence from the Aerobics Center Longitudinal Study (ACLS)

    OpenAIRE

    Le, Tuan D.; Bae, Sejong; Ed Hsu, Chiehwen; Karan P. Singh; Blair, Steven N.; Shang, Ning

    2008-01-01

    BACKGROUND: Cardiorespiratory fitness (CRF) and physical activity (PA) are inversely related to the occurrence of type 2 diabetes (T2D). Both play an important role in reducing serum ferritin (SF) concentration. Increased SF concentration is considered a contributing factor for developing T2D. METHODS: The present cohort study investigated 5,512 adult participants enrolled in the Aerobics Center Longitudinal Study (ACLS) between 1995 and 2001. The subjects completed a comprehensive medical ex...

  13. Association Between Cardiorespiratory Fitness and the Determinants of Glycemic Control Across the Entire Glucose Tolerance Continuum

    DEFF Research Database (Denmark)

    Solomon, Thomas P. J.; Malin, Steven K.; Karstoft, Kristian;

    2015-01-01

    disposition index, a measure of compensatory pancreatic β-cell insulin secretion relative to insulin sensitivity, in subjects representing the entire range of the glucose tolerance continuum. RESEARCH DESIGN AND METHODS: A cohort of subjects (N = 313) with heterogeneous age, sex, BMI, and glycemic control...... underwent measurements of body composition, HbA1c, fasting glucose, oral glucose tolerance (OGTT), and VO2max. OGTT-derived insulin sensitivity (SiOGTT), glucose-stimulated insulin secretion (GSISOGTT), and the disposition index (DIOGTT) (the product of SiOGTT and GSISOGTT) were measured, and associations...... fitness and compromised pancreatic β-cell compensation across the entire glucose tolerance continuum provides additional evidence highlighting the importance of fitness in protection against the onset of a fundamental pathophysiological event that leads to type 2 diabetes....

  14. Anthropometric, physical and cardiorespiratory fitness of 10-16 years children

    OpenAIRE

    Indranil Manna; Swadesh Ranjan Pan; Mohua Chowdhury

    2014-01-01

    Objectives: The present study was undertaken to investigate the anthropometric, physical and cardiorespiratiory fitness of 10-16 yrs children. Background: Talent identification in sports is importance because they represent the achievement level of a particular group in future. There are very limited studies available in Indian context on talent identification in sports. Method: A total of 150 male children of 10-16 yrs age volunteered for this study; were divided equally into 3 groups (i) Pr...

  15. Cardiorespiratory fitness, cardiovascular workload and risk factors among cleaners; a cluster randomized worksite intervention

    DEFF Research Database (Denmark)

    Korshøj, Mette; Krustrup, Peter; Jørgensen, Marie Birk;

    2012-01-01

    fitness and cardiovascular risk factors among cleaners. Cleaners are eligible if they are employed ≥ 20 hours/week, at one of the enrolled companies. In the randomization, strata are formed according to the manager the participant reports to. The clusters will be balanced on the following criteria......: Geographical work location, gender, age and seniority. Cleaners are randomized to either I) a reference group, receiving lectures concerning healthy living, or II) an intervention group, performing worksite aerobic exercise "60 min per week". Data collection will be conducted at baseline, four months and 12...

  16. Occupational demand and human rights. Public safety officers and cardiorespiratory fitness.

    Science.gov (United States)

    Shephard, R J

    1991-08-01

    The issue of discrimination in physically demanding employment, such as police, firefighters, prison guards and military personnel, is contentious. In terms of oxygen transport, the 'action limit' (calling for personnel selection or task redesign) is a steady oxygen consumption of 0.7 L/min, while the maximum permissible limit is 2.1 L/min. Note is taken of the commonly expressed belief that public safety duties are physically demanding, calling for personnel with an aerobic power of at least 3 L/min, or 42 to 45 ml/kg/min. The actual demands of such work can be assessed on small samples by physiological measurements (using heart rate or oxygen consumption meters), but the periods sampled may not be typical of a normal day. A Gestalt can also be formed as to the heaviness of a given job, or a detailed task analysis can be performed; most such analyses of public safety work list distance running and other aerobic activities infrequently. An arbitrary requirement of 'above average fitness' is no longer accepted by courts, but a further approach is to examine the characteristics of those currently meeting the demands of public safety jobs satisfactorily. Young men commonly satisfy the 3 L/min standard, but this is not usually the case for women or older men; in the case of female employees, it also seems unreasonable that they should be expected to satisfy the same standards as men, since a lower body mass reduces the energy cost of most of the tasks that they must perform. A second criterion sometimes applied to physically demanding work (a low vulnerability to heart attacks) is examined critically. It is concluded that the chances that a symptom-free public safety officer will develop a heart attack during a critical solo mission are so low that cardiac risk should not be a condition of employment. Arbitrary age- and sex-related employment criteria are plainly discriminatory, since some women and 65-year-old men have higher levels of physical fitness than the

  17. The Role of Body Habitus in Predicting Cardiorespiratory Fitness: The FRIEND Registry.

    Science.gov (United States)

    Baynard, T; Arena, R A; Myers, J; Kaminsky, L A

    2016-10-01

    This study aimed to validate and cross-validate a non-exercise prediction model from a large and apparently healthy US cohort of individuals who underwent an analysis of body habitus (waist circumference (WC) and body mass index (BMI)) with measured CRF. The large cohort (5 030 individuals) was split into validation (4 030) and cross-validation (1 000) groups, whereby waist circumference and maximal aerobic capacity (VO2max) were assessed by rigorously approved laboratories. VO2max was estimated in 2 multiple regression equations using age, sex and either WC (r=0.77; standard error of the estimate (SEE) 6.70 mLO2∙kg(-1)∙min(-1)) or BMI (r=0.76; SEE 6.89 mLO2∙kg(-1)∙min(-1)).Cross-validation yielded similar results. However, as VO2max increased, there was increased bias, suggesting VO2max may be underestimated at higher values. Both WC and BMI prediction models yielded similar findings, with WC having a slightly smaller SEE. These measures of body habitus appear to be adequate in predicting CRF using non-exercise parameters, even without a measure of physical activity. Caution should be taken when using these equations in more fit individuals.

  18. Effects of acute aerobic exercise on a task-switching protocol and brain-derived neurotrophic factor concentrations in young adults with different levels of cardiorespiratory fitness.

    Science.gov (United States)

    Tsai, Chia-Liang; Pan, Chien-Yu; Chen, Fu-Chen; Wang, Chun-Hao; Chou, Feng-Ying

    2016-07-01

    What is the central question of this study? Neurocognitive functions can be enhanced by acute aerobic exercise, which could be associated with changes in serum brain-derived neurotrophic factor (BDNF) concentrations. We aimed to explore acute exercise-induced changes in BDNF concentrations, neuropsychological and neurophysiological performances when individuals with different levels of cardiorespiratory fitness performed a cognitive task. What is the main finding and its importance? Only young adults with higher cardiorespiratory fitness could attain switching cost and neurophysiological benefits via acute aerobic exercise. The mechanisms might be fitness dependent. Although acute aerobic exercise could enhance serum BDNF concentrations, changes in peripheral BDNF concentrations could not be the potential factor involved in the beneficial effects on neurocognitive performance. This study investigated the effects of acute aerobic exercise on neuropsychological and neurophysiological performances in young adults with different cardiorespiratory fitness levels when performing a task-switching protocol and explored the potential associations between acute aerobic exercise-induced changes in serum brain-derived neurotrophic factor (BDNF) concentrations and various neurocognitive outcomes. Sixty young adults were categorized into one control group (i.e. non-exercise-intervention; n = 20) and two exercise-intervention (EI) groups [i.e. higher (EIH , n = 20) and lower (EIL , n = 20) cardiorespiratory fitness] according to their maximal oxygen consumption. At baseline and after either an acute bout of 30 min of moderate-intensity aerobic exercise or a control period, the neuropsychological and neurophysiological performances and serum BDNF concentrations were measured when the participants performed a task-switching protocol involving executive control and greater demands on working memory. The results revealed that although acute aerobic exercise decreased reaction

  19. A Bayesian Approach to Multistage Fitting of the Variation of the Skeletal Age Features

    Directory of Open Access Journals (Sweden)

    Dong Hua

    2009-01-01

    Full Text Available Accurate assessment of skeletal maturity is important clinically. Skeletal age assessment is usually based on features encoded in ossification centers. Therefore, it is critical to design a mechanism to capture as much as possible characteristics of features. We have observed that given a feature, there exist stages of the skeletal age such that the variation pattern of the feature differs in these stages. Based on this observation, we propose a Bayesian cut fitting to describe features in response to the skeletal age. With our approach, appropriate positions for stage separation are determined automatically by a Bayesian approach, and a model is used to fit the variation of a feature within each stage. Our experimental results show that the proposed method surpasses the traditional fitting using only one line or one curve not only in the efficiency and accuracy of fitting but also in global and local feature characterization.

  20. Effects of 6-month soccer and traditional physical activity programmes on body composition, cardiometabolic risk factors, inflammatory, oxidative stress markers and cardiorespiratory fitness in obese boys.

    Science.gov (United States)

    Seabra, André; Katzmarzyk, Peter; Carvalho, Maria José; Seabra, Ana; Coelho-E-Silva, Manuel; Abreu, Sandra; Vale, Susana; Póvoas, Susana; Nascimento, Henrique; Belo, Luís; Torres, Sandra; Oliveira, José; Mota, Jorge; Santos-Silva, Alice; Rêgo, Carla; Malina, Robert M

    2016-10-01

    Physical activity is important in obesity prevention, but the effectiveness of different physical activity modalities remains to be determined among children. The main purpose of this study was to compare the effects of a 6-month soccer programme and a traditional physical activity programme on changes in body composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status in obese boys. Eighty-eight boys (8-12 years; BMI > +2 standard deviations of WHO reference values) participated in one of three groups: soccer, traditional activity and control. Soccer and traditional activity programmes involved 3 sessions per week for 60-90 min at an average intensity of 70-80% of maximal heart rate. Control group participated in activities of normal daily living. All boys participated in school physical education, two sessions per week of 45-90-min. Measurements were taken at baseline and after 6 months, and included body size and composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status. Physical activity and dietary intake were assessed before and immediately following the intervention. The three groups had similar characteristics at baseline. After 6 months, both intervention groups had significantly lower relative fatness (% fat), waist circumference and total cholesterol, and higher cardiorespiratory fitness, self-esteem, perceived physical competence and attraction to physical activity compared with control group. In conclusion, physical activity interventions over 6 months positively influenced several indicators of health status among obese boys. The results also suggested that soccer has the potential as an effective tool for the prevention and reduction of childhood obesity and associated consequences.

  1. Inter-participant variability in daily physical activity and sedentary time among male youth sport footballers: independent associations with indicators of adiposity and cardiorespiratory fitness.

    Science.gov (United States)

    Fenton, Sally A M; Duda, Joan L; Barrett, Timothy

    2016-01-01

    Participation in youth sport is assumed to promote and contribute towards more physically active lifestyles among children and adolescents. The aim of this study was to examine inter-participant variability in objectively measured habitual physical activity (PA) behaviours and sedentary time among youth sport participants and their implications for health. One-hundred-and-eighteen male youth sport footballers (Mean ± s = 11.72 ± 1.60) wore a GT3X accelerometer for 7 days. Average daily PA [min · day(-1), in light (LPA), moderate (MPA), vigorous (VPA) and combined moderate-to-vigorous (MVPA)] and sedentary time were calculated. Participants' body mass index adjusted for age and sex (BMI-standard deviation score), per cent body fat (BF%), waist circumference and cardiorespiratory fitness were assessed. Results revealed that variability in daily PA behaviours and sedentary time (min · day(-1)) was associated with BMI-standard deviation score [VPA (-), MVPA (-)], BF% [sedentary time (+), VPA (-), MVPA (-)], waist circumference [sedentary time (+), LPA (-)] and cardiorespiratory fitness [sedentary time (-), MPA (+), VPA (+), MVPA (+)]. Whilst sedentary time and MVPA were not related to health outcomes independent of one another, associations with markers of adiposity and cardiorespiratory fitness were stronger for sedentary time. Sedentary time was also significantly positively related to waist circumference independent of VPA. Results demonstrate inter-participant variability in habitual PA and sedentary time among youth sport participants which holds implications for their health. Thus, promoting PA and, in particular, reducing sedentary time may contribute towards the prevention of adverse health consequences associated with a physically inactive lifestyle for children and adolescents active in the youth sport context.

  2. Effects of 6-month soccer and traditional physical activity programmes on body composition, cardiometabolic risk factors, inflammatory, oxidative stress markers and cardiorespiratory fitness in obese boys.

    Science.gov (United States)

    Seabra, André; Katzmarzyk, Peter; Carvalho, Maria José; Seabra, Ana; Coelho-E-Silva, Manuel; Abreu, Sandra; Vale, Susana; Póvoas, Susana; Nascimento, Henrique; Belo, Luís; Torres, Sandra; Oliveira, José; Mota, Jorge; Santos-Silva, Alice; Rêgo, Carla; Malina, Robert M

    2016-10-01

    Physical activity is important in obesity prevention, but the effectiveness of different physical activity modalities remains to be determined among children. The main purpose of this study was to compare the effects of a 6-month soccer programme and a traditional physical activity programme on changes in body composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status in obese boys. Eighty-eight boys (8-12 years; BMI > +2 standard deviations of WHO reference values) participated in one of three groups: soccer, traditional activity and control. Soccer and traditional activity programmes involved 3 sessions per week for 60-90 min at an average intensity of 70-80% of maximal heart rate. Control group participated in activities of normal daily living. All boys participated in school physical education, two sessions per week of 45-90-min. Measurements were taken at baseline and after 6 months, and included body size and composition, cardiometabolic risk factors, inflammatory and oxidative markers, cardiorespiratory fitness and perceived psychological status. Physical activity and dietary intake were assessed before and immediately following the intervention. The three groups had similar characteristics at baseline. After 6 months, both intervention groups had significantly lower relative fatness (% fat), waist circumference and total cholesterol, and higher cardiorespiratory fitness, self-esteem, perceived physical competence and attraction to physical activity compared with control group. In conclusion, physical activity interventions over 6 months positively influenced several indicators of health status among obese boys. The results also suggested that soccer has the potential as an effective tool for the prevention and reduction of childhood obesity and associated consequences. PMID:26890580

  3. Muscle strength, power and cardiorespiratory fitness are associated with bone mineral density in men aged 31-60 years

    DEFF Research Database (Denmark)

    Schwarz, Peter; Jørgensen, Niklas; Nielsen, Barbara;

    2014-01-01

    BACKGROUND: Osteoporotic fractures represent a growing economical burden to society, not only because of fractures in women, but also because of an increasing number of fractures in men. AIMS: In this cross-sectional study we aimed to investigate the association of muscular and cardio-respiratory...

  4. Variability of cardio-respiratory, electromyographic, and perceived exertion responses at the walk-run transition in a sample of young men controlled for anthropometric and fitness characteristics.

    Science.gov (United States)

    Monteiro, Walace D; Farinatti, Paulo T V; de Oliveira, Carlos G; Araújo, Claudio Gil S

    2011-06-01

    The cardio-respiratory (heart rate, HR; oxygen uptake, VO(2;) expired carbon dioxide, VCO(2); ventilation, VE), electromyographic (EMG; medial gastrocnemius, vastus lateralis, rectus femoralis, and anterior tibialis), and perceived exertion (PE) responses during a protocol for the determination of the walk-run transition speed (WRTS) were investigated. From an initial sample of 453 volunteers, 12 subjects matched for age, anthropometric characteristics [height, weight, lower limb length (LLL)], cardio-respiratory fitness (peak oxygen consumption, VO(2peak); ventilatory threshold, VT; maximal HR), and habitual physical activity levels were selected (age = 18.6 ± 0.5 years; height = 174.5 ± 1.4 cm; weight = 66.4 ± 1.1 kg; LLL = 83.3 ± 1.2 cm, VO(2peak) = 52.2 ± 2.2 ml kg(-1) min(-1); VT = 39.8 ± 2.6 ml kg(-1) min(-1)). The highly reproducible WRTS determination protocol (ICC = 0.92; p running velocities (from 80 to 120% of WRTS) was compared to WRTS variation. The coefficient of variation for WRTS was 7.8%, which was within the range of variability for age, anthropometric variables, VO(2peak), and maximal HR (from 5 to 12%). Cardio-respiratory responses at WRTS had a greater variation (VO(2) about 50%; VE/VCO(2) about 35%; VE/VO(2) about 45%; HR about 30%). The highest variation was found for PE (from 70 to 90%) whereas EMG variables showed the lowest variation (from 25 to 30%). Linear regression between EMG series and VO(2) data showed that VO(2) reflected the increase in muscle activity only before the WRTS. These results support the hypothesis that the walk-run transition phenomenon is determined by mechanical variables such as limb length and its relationship to biomechanical model rather than by metabolic factors.

  5. Effects of a 2-year school-based daily physical activity intervention on cardiorespiratory fitness: the Sogndal school-intervention study

    DEFF Research Database (Denmark)

    Resaland, G K; Andersen, Lars Bo; Mamen, A;

    2011-01-01

    The aim of this study was to describe changes in children's cardiorespiratory fitness (CRF) following a school-based physical activity (PA) intervention. In total, 259 children (age 9.3+/-0.3 years) were invited to participate, of whom 256 participated. The children from the intervention school (63...... boys, 62 girls) carried out 60-min PA over 2 school years. The children from the control school (62 boys, 69 girls) had the regular curriculum-defined amount of physical education in school, i.e. 45 min twice weekly. One hundred and eighty-eight children (73.4%) successfully completed both the baseline......L/kg/min more than the children from the control school. This VO(2peak) value was adjusted for both sex and baseline VO(2peak). Boys and girls demonstrated similar VO(2peak) responses. The intervention, primarily carried out at a moderate intensity, had the biggest impact in children with low initial CRF levels...

  6. Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle.

    Directory of Open Access Journals (Sweden)

    Dominique-Marie Votion

    Full Text Available BACKGROUND: Within the animal kingdom, horses are among the most powerful aerobic athletic mammals. Determination of muscle respiratory capacity and control improves our knowledge of mitochondrial physiology in horses and high aerobic performance in general. METHODOLOGY/PRINCIPAL FINDINGS: We applied high-resolution respirometry and multiple substrate-uncoupler-inhibitor titration protocols to study mitochondrial physiology in small (1.0-2.5 mg permeabilized muscle fibres sampled from triceps brachii of healthy horses. Oxidative phosphorylation (OXPHOS capacity (pmol O(2 • s(-1 • mg(-1 wet weight with combined Complex I and II (CI+II substrate supply (malate+glutamate+succinate increased from 77 ± 18 in overweight horses to 103 ± 18, 122 ± 15, and 129 ± 12 in untrained, trained and competitive horses (N = 3, 8, 16, and 5, respectively. Similar to human muscle mitochondria, equine OXPHOS capacity was limited by the phosphorylation system to 0.85 ± 0.10 (N = 32 of electron transfer capacity, independent of fitness level. In 15 trained horses, OXPHOS capacity increased from 119 ± 12 to 134 ± 37 when pyruvate was included in the CI+II substrate cocktail. Relative to this maximum OXPHOS capacity, Complex I (CI-linked OXPHOS capacities were only 50% with glutamate+malate, 64% with pyruvate+malate, and 68% with pyruvate+malate+glutamate, and ~78% with CII-linked succinate+rotenone. OXPHOS capacity with glutamate+malate increased with fitness relative to CI+II-supported ETS capacity from a flux control ratio of 0.38 to 0.40, 0.41 and 0.46 in overweight to competitive horses, whereas the CII/CI+II substrate control ratio remained constant at 0.70. Therefore, the apparent deficit of the CI- over CII-linked pathway capacity was reduced with physical fitness. CONCLUSIONS/SIGNIFICANCE: The scope of mitochondrial density-dependent OXPHOS capacity and the density-independent (qualitative increase of CI-linked respiratory capacity with increased

  7. APOE genotype and cardio-respiratory fitness interact to determine adiposity in 8-year-old children from the Tasmanian Infant Health Survey.

    Directory of Open Access Journals (Sweden)

    Justine A Ellis

    Full Text Available APOE plays a well established role in lipid metabolism. Animal model evidence suggests APOE may also be associated with adiposity, but this has not been thoroughly investigated in humans. We measured adiposity (BMI, truncal fat mass, waist circumference, physical activity (PA, cardiorespiratory fitness and APOE genotype (E2, E3, E4 in 292 8-year-old children from the Tasmanian Infant Health Survey (TIHS, an Australian population-based prospective birth cohort. Our aims were to examine the association of APOE with child adiposity, and to examine the interplay between this association and other measured factors. We found that APOE was associated with child lipid profiles. APOE was also associated with child adiposity measures. The association was E4 allele-specific, with adiposity lower in the E4-containing group (BMI: Mean difference -0.90 kg/m²; 95% confidence intervals (CI -1.51, -0.28; p = 0.004. The association of APOE4 with lower BMI differed by fitness status (difference in effect p = 0.002, and was more evident among the less fit (mean difference -1.78 kg/m²; 95% CI -2.74, -0.83; p<0.001. Additionally, associations between BMI and lipids were only apparent in those of lower fitness who did not carry APOE4. Similar overall findings were observed when truncal fat mass and waist circumference were used as alternative adiposity measures. APOE4 and cardiorespitatory fitness could interact to influence child adiposity. In studies addressing the genetic determinants of childhood obesity, the context of child fitness should also be taken into account.

  8. Longitudinal influence of musculo-skeletal injuries and extra physical education on physical fitness in schoolchildren

    DEFF Research Database (Denmark)

    Rexen, C T; Ersbøll, A K; Wedderkopp, N;

    2016-01-01

    The aims of this study were to investigate if (A) injuries and (B) increased physical education (PE) influenced the development of physical fitness in schoolchildren. Simultaneously, to investigate if a possible PE effect was modified by sport participation outside school hours. This was a longit...... participation outside school hours. In conclusion, extra PE had a positive effect, whereas injuries had a negative effect on physical fitness development in schoolchildren.......The aims of this study were to investigate if (A) injuries and (B) increased physical education (PE) influenced the development of physical fitness in schoolchildren. Simultaneously, to investigate if a possible PE effect was modified by sport participation outside school hours...... fitness tests measured four times. Information of injury and sport was derived from weekly automated mobile phone text messages surveying the presence of musculo-skeletal pain and organized sport participation. Injury and extra PE both influenced the development of physical fitness. Injury decreased...

  9. Effects of vitamin D and quercetin, alone and in combination, on cardiorespiratory fitness and muscle function in physically active male adults

    Directory of Open Access Journals (Sweden)

    Scholten SD

    2015-07-01

    Full Text Available Shane D Scholten,1 Igor N Sergeev,2 Qingming Song,3 Chad B Birger41Exercise and Sport Sciences, Augustana College, Sioux Falls, 2Department of Health and Nutritional Sciences, South Dakota State University, Brookings, SD, 3Gold Green Farm Corporation, Hammonton, NJ, 4Center for Health Outcomes and Prevention Research, Sanford Research, Sioux Falls, SD, USAIntroduction: Vitamin D and the antioxidant quercetin, are promising agents for improving physical performance because of their possible beneficial effects on muscular strength and cardiorespiratory fitness.Purpose: The purpose of this study was to determine the effects of increased intakes of vitamin D, quercetin, and their combination on antioxidant status, the steroid hormone regulators of muscle function, and measures of physical performance in apparently healthy male adults engaged in moderate-to-vigorous-intensity exercise training.Methods: A total of 40 adult male participants were randomized to either 4,000 IU vitamin D/d, 1,000 mg/d quercetin, vitamin D plus quercetin, or placebo for 8 weeks. Measures of cardiorespiratory fitness and muscle function, blood markers for antioxidant and vitamin D status, and hormones 1,25-dihydroxyvitamin D3 (1,25(OH2D3 and testosterone were measured pre- and postsupplementation.Results: At enrollment, 88.6% of participants were vitamin D sufficient (serum 25-hydroxyvitamin D >50 nmol/L and had normal serum testosterone levels. Supplementation with vitamin D significantly increased serum 25(OHD concentration (by 87.3% in the vitamin D group, P<0.001 and was associated with an increasing trend of testosterone concentration. There were no changes in concentration of 1,25(OH2D3 and markers of antioxidant status associated with vitamin D or quercetin supplementation. No improvements in physical performance measures associated with vitamin D and quercetin supplementation were found.Conclusion: The findings obtained demonstrate that long-term vitamin D and

  10. Is Moderate Intensity Exercise Training Combined with High Intensity Interval Training More Effective at Improving Cardiorespiratory Fitness than Moderate Intensity Exercise Training Alone?

    Directory of Open Access Journals (Sweden)

    Brendon H. Roxburgh, Paul B. Nolan, Ryan M. Weatherwax, Lance C. Dalleck

    2014-09-01

    Full Text Available The purpose of this study was to compare the effectiveness of either continuous moderate intensity exercise training (CMIET alone vs. CMIET combined with a single weekly bout of high intensity interval training (HIIT on cardiorespiratory fitness. Twenty nine sedentary participants (36.3 ± 6.9 yrs at moderate risk of cardiovascular disease were recruited for 12 weeks of exercise training on a treadmill and cycle ergometer. Participants were randomised into three groups: CMIET + HIIT (n = 7; 8-12 x 60 sec at 100% VO2max, 150 sec active recovery, CMIET (n = 6; 30 min at 45-60% oxygen consumption reserve (VO2R and a sedentary control group (n = 7. Participants in the CMIET + HIIT group performed a single weekly bout of HIIT and four weekly sessions of CMIET, whilst the CMIET group performed five weekly CMIET sessions. Probabilistic magnitude-based inferences were determined to assess the likelihood that the true value of the effect represents substantial change. Relative VO2max increased by 10.1% (benefit possible relative to control in in the CMIET + HIIT group (32.7 ± 9.2 to 36.0 ± 11.5 mL·kg-1·min-1 and 3.9% (benefit possible relative to control in the CMIET group (33.2 ± 4.0 to 34.5 ± 6.1 mL·kg-1·min-1, whilst there was a 5.7% decrease in the control group (30.0 ± 4.6 to 28.3 ± 6.5 mL·kg-1·min-1. It was ‘unclear’ if a clinically significant difference existed between the effect of CMIET + HIIT and CMIET on the change in VO2max. Both exercising groups showed clinically meaningful improvements in VO2max. Nevertheless, it remains ‘unclear’ whether one type of exercise training regimen elicits a superior improvement in cardiorespiratory fitness relative to its counterpart.

  11. The effects of 8 weeks of motor skill training on cardiorespiratory fitness and endurance performance in children with developmental coordination disorder.

    Science.gov (United States)

    Farhat, Faiçal; Masmoudi, Kaouthar; Hsairi, Ines; Smits-Engelsman, Bouwien C M; Mchirgui, Radhouane; Triki, Chahnez; Moalla, Wassim

    2015-12-01

    Interventions based on everyday motor skills have been developed to be effective in children with developmental coordination disorder (DCD). The purpose of the present study was to examine the effects of motor skill training on exercise tolerance and cardiorespiratory fitness in children with DCD. Children were assigned to 3 groups: an experimental training group comprising 14 children with DCD, a control nontraining group comprising 13 children with DCD, and a control nontraining group comprising 14 typically developed children. All participants were tested twice with an interval of 8-weeks on a cardiopulmonary exercise test, pulmonary function testing, and a 6-min walk test. After the training program the maximal power output was significantly increased for DCD group at anaerobic threshold (p Children with DCD that participated in the training program improved their walking distance (t (13) = -9.08, p developed group did not change on any of the measures. In conclusion, training delayed reaching the anaerobic threshold and improved aerobic endurance and exercise tolerance in children with DCD.

  12. Associations between sports participation, levels of moderate to vigorous physical activity and cardiorespiratory fitness in childrenand adolescents

    DEFF Research Database (Denmark)

    Silva, Gustavo; Andersen, Lars Bo; Aires, Luisa;

    2013-01-01

    was assessed by questionnaire and habitual physical activity (PA) was measured objectively with accelerometers. The 20-m shuttle-run test was used to estimate CRF. Logistic regression analyses were carried out with CRF as the outcome. The odds ratio (OR) for being fit was greater for those who comply with60min...

  13. Physical activity pattern, cardiorespiratory fitness, and socioeconomic status in the SCAPIS pilot trial - A cross-sectional study.

    Science.gov (United States)

    Lindgren, Martin; Börjesson, Mats; Ekblom, Örjan; Bergström, Göran; Lappas, Georgios; Rosengren, Annika

    2016-12-01

    Living in a low socioeconomic status (SES) area is associated with an increased risk of cardiovascular events and all-cause mortality. Previous studies have suggested a socioeconomic gradient in daily physical activity (PA), but have mainly relied on self-reported data, and individual rather than residential area SES. This study aimed to investigate the relationships between residential area SES, PA pattern, compliance with PA-recommendations and fitness in a Swedish middle-aged population, using objective measurements. We included 948 individuals from the SCAPIS pilot study (Gothenburg, Sweden, 2012, stratified for SES, 49% women, median age: 58 years), in three low and three high SES districts. Accelerometer data were summarized into intensity-specific categories: sedentary (SED), low (LIPA), and medium-to-vigorous PA (MVPA). Fitness was estimated by submaximal ergometer testing. Participants of low SES areas had a more adverse cardiovascular disease risk factor profile (smoking: 20% vs. 6%; diabetes: 9% vs. 3%; hypertension: 38% vs. 25%; obesity: 31% vs. 13%), and less frequently reached 150 min of MVPA per week (67% vs. 77%, odds ratio [OR] = 0.61; 95% confidence interval [95% CI] = 0.46-0.82), from 10-minute bouts (19% vs. 31%, OR = 0.53, 95% CI = 0.39-0.72). Individuals in low SES areas showed lower PA levels (mean cpm: 320 vs. 348) and daily average MVPA (29.9 vs. 35.5 min), and 12% lower fitness (25.1 vs. 28.5 mL × min(- 1) × kg(- 1)) than did those in high SES areas. Reduced PA and fitness levels may contribute to social inequalities in health, and should be a target for improved public health in low SES areas. PMID:27413660

  14. Four weeks of running sprint interval training improves cardiorespiratory fitness in young and middle-aged adults.

    Science.gov (United States)

    Willoughby, Taura N; Thomas, Matthew P L; Schmale, Matthew S; Copeland, Jennifer L; Hazell, Tom J

    2016-01-01

    The purpose of this study was to determine the effectiveness of a 4-week running sprint interval training protocol to improve both aerobic and anaerobic fitness in middle-aged adults (40-50 years) as well as compare the adaptations to younger adults (20-30 years). Twenty-eight inactive participants - 14 young 20-30-year-olds (n = 7 males) and 14 middle-aged 40-50-year-olds (n = 5 males) - completed 4 weeks of running sprint interval training (4 to 6, 30-s "all-out" sprints on a curved, self-propelled treadmill separated by 4 min active recovery performed 3 times per week). Before and after training, all participants were assessed for maximal oxygen consumption (VO2max), 2000 m time trial performance, and anaerobic performance on a single 30-s sprint. There were no interactions between group and time for any tested variable, although training improved relative VO2max (young = 3.9, middle-aged = 5.2%; P sprint speed (young = 9.3, middle-aged = 2.2%; P sprint speed (young = 6.8, middle-aged = 11.6%; P sprint test. The current study demonstrates that a 4-week running sprint interval training programme is equally effective at improving aerobic and anaerobic fitness in younger and middle-aged adults.

  15. Testing Methods of Adolescents’ Cardiorespiratory Fitness%青少年心肺耐力测试方法的研究

    Institute of Scientific and Technical Information of China (English)

    叶心明; 尹小俭; 季浏; 刘笑

    2014-01-01

    目的::分析和探讨1000(800)米跑和20mSRT对测量青少年心肺耐力的测试效度,为有效地制定评价青少年心肺耐力的测试方法提供参考依据。方法:随机抽取上海市A中学13-15岁共61名(男29名,女32名)初中学生作为研究对象,运用ROC曲线,多重线性回归等方法分析和探讨1000(800)米跑,20mSRT和跑台测试法直接测得的VO2 max之间的相互关系。结果与结论:(1)1000米跑,20mSRT与跑台直接测试法测得的 VO2 max的相关系数男生分别为0.440和0.468,女生(800米跑)为0.513和0.765;在测量青少年心肺耐力方面,20mSRT优于1000米(男生)跑和800米(女生)跑。(2)以跑台测试所得的VO2 max为金标准,男生1000米跑,20mSRT所测得VO2 max的ROC曲线下面积分别为0.571和0.688,女生800米跑,20mSRT的面积分别为0.523和0.661;(3)VO2max与20mSRT次数之间的回归方程式:VO2max=115.54356-(1.93803×年龄)-(7.13359×性别)-(1.86024× BMI)-(0.065772× N)(男生为0,女生为1, N为20mSRT次数),方程式与VO2max的相关系数为0.713。%Objective:This study attempts to investigate the measurement of the validation of cardiorespiratory fit-ness through 1000 (800) -running test and 20mSRT in order to provide reference for the future development of the test method of evaluating cardiorespiratory fitness of children and adolescents effectively. Method:61 students (29 males and 32 females) are randomly selected as research objects from middle schools in Shanghai to analyze the relevance of differ-ent VO2 max from 1000(800) -meter running test, 20mSRT and treadmill test respectively by using ROC and multiple linear regression analysis. Results and Conclusion:(1)The correlation coefficient of VO2max from 1000-meter running test (male) and 20mSRT is 0. 440 and 0. 468 respectively while that of 800-meter running test (female) and 20mSRT is 0. 513 and 0. 765 respectively. 20mSRT is better than 1000(800) -running test in terms of measuring the

  16. Cardiorespiratory fitness is associated with brain structure, cognition, and mood in a middle-aged cohort at risk for Alzheimer's disease.

    Science.gov (United States)

    Boots, Elizabeth A; Schultz, Stephanie A; Oh, Jennifer M; Larson, Jordan; Edwards, Dorothy; Cook, Dane; Koscik, Rebecca L; Dowling, Maritza N; Gallagher, Catherine L; Carlsson, Cynthia M; Rowley, Howard A; Bendlin, Barbara B; LaRue, Asenath; Asthana, Sanjay; Hermann, Bruce P; Sager, Mark A; Johnson, Sterling C; Okonkwo, Ozioma C

    2015-09-01

    Cardiorespiratory fitness (CRF) is an objective measure of habitual physical activity (PA), and has been linked to increased brain structure and cognition. The gold standard method for measuring CRF is graded exercise testing (GXT), but GXT is not feasible in many settings. The objective of this study was to examine whether a non-exercise estimate of CRF is related to gray matter (GM) volumes, white matter hyperintensities (WMH), cognition, objective and subjective memory function, and mood in a middle-aged cohort at risk for Alzheimer's disease (AD). Three hundred and fifteen cognitively healthy adults (mean age =58.58 years) enrolled in the Wisconsin Registry for Alzheimer's Prevention underwent structural MRI scanning, cognitive testing, anthropometric assessment, venipuncture for laboratory tests, and completed a self-reported PA questionnaire. A subset (n = 85) underwent maximal GXT. CRF was estimated using a previously validated equation incorporating sex, age, body-mass index, resting heart rate, and self-reported PA. Results indicated that the CRF estimate was significantly associated with GXT-derived peak oxygen consumption, validating its use as a non-exercise CRF measure in our sample. Support for this finding was seen in significant associations between the CRF estimate and several cardiovascular risk factors. Higher CRF was associated with greater GM volumes in several AD-relevant brain regions including the hippocampus, amygdala, precuneus, supramarginal gyrus, and rostral middle frontal gyrus. Increased CRF was also associated with lower WMH and better cognitive performance in Verbal Learning & Memory, Speed & Flexibility, and Visuospatial Ability. Lastly, CRF was negatively correlated with self- and informant-reported memory complaints, and depressive symptoms. Together, these findings suggest that habitual participation in physical activity may provide protection for brain structure and cognitive function, thereby decreasing future risk for AD.

  17. Cardiorespiratory fitness is associated with brain structure, cognition, and mood in a middle-aged cohort at risk for Alzheimer’s disease

    Science.gov (United States)

    Boots, Elizabeth A.; Schultz, Stephanie A.; Oh, Jennifer M.; Larson, Jordan; Edwards, Dorothy; Cook, Dane; Koscik, Rebecca L.; Dowling, Maritza N.; Gallagher, Catherine L.; Carlsson, Cynthia M.; Rowley, Howard A.; Bendlin, Barbara B.; LaRue, Asenath; Asthana, Sanjay; Hermann, Bruce P.; Sager, Mark A.; Johnson, Sterling C.; Okonkwo, Ozioma C.

    2014-01-01

    Cardiorespiratory fitness (CRF) is an objective measure of habitual physical activity (PA), and has been linked to increased brain structure and cognition. The gold standard method for measuring CRF is graded exercise testing (GXT), but GXT is not feasible in many settings. The objective of this study was to examine whether a non-exercise estimate of CRF is related to gray matter (GM) volumes, white matter hyperintensities (WMH), cognition, objective and subjective memory function, and mood in a middle-aged cohort at risk for Alzheimer’s disease (AD). Three hundred and fifteen cognitively healthy adults (mean age = 58.58 years) enrolled in the Wisconsin Registry for Alzheimer’s Prevention underwent structural MRI scanning, cognitive testing, anthropometric assessment, venipuncture for laboratory tests, and completed a self-reported PA questionnaire. A subset (n=85) underwent maximal GXT. CRF was estimated using a previously validated equation incorporating sex, age, body-mass index, resting heart rate, and self-reported PA. Results indicated that the CRF estimate was significantly associated with GXT-derived peak oxygen consumption, validating its use as a non-exercise CRF measure in our sample. Support for this finding was seen in significant associations between the CRF estimate and several cardiovascular risk factors. Higher CRF was associated with greater GM volumes in several AD-relevant brain regions including the hippocampus, amygdala, precuneus, supramarginal gyrus, and rostral middle frontal gyrus. Increased CRF was also associated with lower WMH and better cognitive performance in Verbal Learning & Memory, Speed & Flexibility, and Visuospatial Ability. Lastly, CRF was negatively correlated with self- and informant-reported memory complaints, and depressive symptoms. Together, these findings suggest that habitual participation in physical activity may provide protection for brain structure and cognitive function, thereby decreasing future risk for AD

  18. Independent Associations between Sedentary Time, Moderate-To-Vigorous Physical Activity, Cardiorespiratory Fitness and Cardio-Metabolic Health: A Cross-Sectional Study

    Science.gov (United States)

    Lefevre, Johan; Wijtzes, Anne; Charlier, Ruben; Mertens, Evelien; Bourgois, Jan G.

    2016-01-01

    We aimed to study the independent associations of sedentary time (ST), moderate-to-vigorous physical activity (MVPA), and objectively measured cardiorespiratory fitness (CRF) with clustered cardio-metabolic risk and its individual components (waist circumference, fasting glucose, HDL-cholesterol, triglycerides and blood pressure). We also investigated whether any associations between MVPA or ST and clustered cardio-metabolic risk were mediated by CRF. MVPA, ST, CRF and individual cardio-metabolic components were measured in a population-based sample of 341 adults (age 53.8 ± 8.9 years; 61% men) between 2012 and 2014. MVPA and ST were measured with the SenseWear pro 3 Armband and CRF was measured with a maximal exercise test. Multiple linear regression models and the product of coefficients method were used to examine independent associations and mediation effects, respectively. Results showed that low MVPA and low CRF were associated with a higher clustered cardio-metabolic risk (β = -0.26 and β = -0.43, both p<0.001, respectively). CRF explained 73% of the variance in the association between MVPA and clustered cardio-metabolic risk and attenuated this association to non-significance. After mutual adjustment for MVPA and ST, CRF was the most important risk factor for a higher clustered cardio-metabolic risk (β = -0.39, p<0.001). In conclusion, because of the mediating role of CRF, lifestyle-interventions need to be feasible yet challenging enough to lead to increases in CRF to improve someone’s cardio-metabolic health. PMID:27463377

  19. ASSOCIATION OF CARDIORESPIRATORY FITNESS WITH ELEVATED HEPATIC ENZYME AND LIVER FAT IN JAPANESE PATIENTS WITH IMPAIRED GLUCOSE TOLERANCE AND TYPE 2 DIABETES MELLITUS

    Directory of Open Access Journals (Sweden)

    Mayumi Nagano

    2010-09-01

    Full Text Available No study has so far determined whether a favorable level of cardiorespiratory fitness (CF contributes to a reduced risk of elevated hepatic enzymes and a high degree of liver fat in patients having various metabolic risks. This study investigated the association between the maximal oxygen uptake (VO2 max and the prevalence of elevated liver enzymes and high liver fat, while considering such factors as abdominal obesity, hyperinsulinemia and the other metabolic risks. The study enrolled newly diagnosed Japanese patients (n = 84; 52 males and 32 females; aged 25-69 years with impaired glucose tolerance (IGT and type 2 diabetes mellitus (Type2DM who did not receive any intervention or pharmacological therapy. The subjects were divided into 3 groups according to the distribution of the VO2max for each sex. The odds ratios (ORs for the prevalence of elevated aspartate and alanine aminotransferase (AST and ALT and high degree of liver fat adjusted for age, sex, disease type, daily ethanol intake, and current smoking were significantly lower in the moderate- and high CF groups in comparison to the low CF group. In addition, a significant OR for AST was maintained in the moderate and high CF group after adjusting for abdominal obesity and/or hyperinsulinemia. The significant ORs for the prevalence of elevated ALT and a high degree of liver fat were attenuated after adjusting for abdominal obesity and/or hyperinsulinemia. No significant OR for the prevalence of elevated gamma-glutamyl transferase (GGT was recognized in all logistic models. These results indicated that CF was negatively and independently associated with the prevalence of elevated AST even in Japanese diabetic patients having various metabolic risks. It was concluded that the AST level might be useful as a simple marker reflecting physical inactivity in such subjects

  20. The effects of four weeks of creatine supplementation and high-intensity interval training on cardiorespiratory fitness: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Cramer Joel T

    2009-11-01

    Full Text Available Abstract Background High-intensity interval training has been shown to be a time-efficient way to induce physiological adaptations similar to those of traditional endurance training. Creatine supplementation may enhance high-intensity interval training, leading to even greater physiological adaptations. The purpose of this study was to determine the effects of high-intensity interval training (HIIT and creatine supplementation on cardiorespiratory fitness and endurance performance (maximal oxygen consumption (VO2PEAK, time-to-exhaustion (VO2PEAKTTE, ventilatory threshold (VT, and total work done (TWD in college-aged men. Methods Forty-three recreationally active men completed a graded exercise test to determine VO2PEAK, VO2PEAKTTE, and VT. In addition, participants completed a time to exhaustion (TTE ride at 110% of the maximum workload reached during the graded exercise test to determine TWD (TTE (sec × W = J. Following testing, participants were randomly assigned to one of three groups: creatine (creatine citrate (Cr; n = 16, placebo (PL; n = 17, or control (n = 10 groups. The Cr and PL groups completed four weeks of HIIT prior to post-testing. Results Significant improvements in VO2PEAK and VO2PEAKTTE occurred in both training groups. Only the Cr group significantly improved VT (16% vs. 10% improvement in PL. No changes occurred in TWD in any group. Conclusion In conclusion, HIIT is an effective and time-efficient way to improve maximal endurance performance. The addition of Cr improved VT, but did not increase TWD. Therefore, 10 g of Cr per day for five days per week for four weeks does not seem to further augment maximal oxygen consumption, greater than HIIT alone; however, Cr supplementation may improve submaximal exercise performance.

  1. Evaluation of an exercise field test using heart rate monitors to assess cardiorespiratory fitness and heart rate recovery in an asymptomatic population.

    Directory of Open Access Journals (Sweden)

    Crystal L Coolbaugh

    Full Text Available PURPOSE: Measures of cardiorespiratory fitness (CRF and heart rate recovery (HRR can improve risk stratification for cardiovascular disease, but these measurements are rarely made in asymptomatic individuals due to cost. An exercise field test (EFT to assess CRF and HRR would be an inexpensive method for cardiovascular disease risk assessment in large populations. This study assessed 1 the predictive accuracy of a 12-minute run/walk EFT for estimating CRF ([Formula: see text] and 2 the accuracy of HRR measured after an EFT using a heart rate monitor (HRM in an asymptomatic population. METHODS: Fifty subjects (48% women ages 18-45 years completed a symptom-limited exercise tolerance test (ETT (Bruce protocol and an EFT on separate days. During the ETT, [Formula: see text] was measured by a metabolic cart, and heart rate was measured continuously by a HRM and a metabolic cart. RESULTS: EFT distance and sex independently predicted[Formula: see text]. The average absolute difference between observed and predicted [Formula: see text] was 0.26 ± 3.27 ml·kg-1·min-1 for our model compared to 7.55 ± 3.64 ml·kg-1·min-1 for the Cooper model. HRM HRR data were equivalent to respective metabolic cart values during the ETT. HRR at 1 minute post-exercise during ETT compared to the EFT had a moderate correlation (r=0.75, p<0.001. CONCLUSION: A more accurate model to estimate CRF from a 12-minute run/walk EFT was developed, and HRR can be measured using a HRM in an asymptomatic population outside of clinical settings.

  2. Cross-sectional association between maximal estimated cardiorespiratory fitness, cardiometabolic risk factors and metabolic syndrome for men and women in the Aerobics Center Longitudinal Study

    Science.gov (United States)

    Artero, Enrique G.; Sui, Xuemei; Lee, Duck-chul; Church, Timothy S.; Blair, Steven N.

    2013-01-01

    Objective To examine the relationship between estimated maximal cardiorespiratory fitness (CRF) and metabolic syndrome (MetS). Patients Aerobics Center Longitudinal Study (N=38,659) participants examined between 1979–2006. Methods We performed a cross-sectional analysis of participants to examine CRF levels defined as low (lower 20%), moderate (middle 40%) and high (upper 40%) of age/gender specific distributions versus NCEP derived MetSyn expressed as a summed z-score continuous variable. We used a general linear model for continuous variables, chi-square for distribution of categorical variables, and multiple linear regression for single and cumulative MetS scores adjusted for BMI, smoking status, alcohol intake and family history of cardiovascular disease. Results We observed significant inverse trends for MetS vs. CRF in both genders (p-for-trend, < 0.001). CRF associations vs. individual components were: Waist circumference (men, β= −0.14, r2 = 0.78; women, β= −0.04, r2 = 0.71), triglycerides (men, β= −0.29, r2 = 0.18; women, β= −0.17, r2 = 0.18), HDL-cholesterol (men, β= 0.25, r2 = 0.17; women, β= 0.08, r2 = 0.19), fasting glucose (men, β= −0.09, r2 = 0.09; women, β= 0.09, r2 = 0.01), systolic blood pressure (men, β= −0.09, r2 = 0.09; women, β= −0.01, r2 = 0.21), and diastolic blood pressure (men, β= −0.07, r2 = 0.12; women, β= −0.05, r2 = 0.14). All associations except for systolic blood pressure (both genders) and glucose (women) are significant (p<0.001). Conclusion CRF demonstrated a strong inverse relationship with MetS in both genders with the strongest single associative component being waist circumference. PMID:23391253

  3. Seasonal variation in objectively measured physical activity, sedentary time, cardio-respiratory fitness and sleep duration among 8–11 year-old Danish children: a repeated-measures study

    DEFF Research Database (Denmark)

    Hjorth, Mads F.; Chaput, Jean-Philippe; Michaelsen, Kim;

    2013-01-01

    BACKGROUND: Understanding fluctuations in lifestyle indicators is important to identify relevant time periods to intervene in order to promote a healthy lifestyle; however, objective assessment of multiple lifestyle indicators has never been done using a repeated-measures design. The primary aim...... was, therefore, to examine between-season and within-week variation in physical activity, sedentary behaviour, cardio-respiratory fitness and sleep duration among 8–11 year-old children. METHODS: A total of 1021 children from nine Danish schools were invited to participate and 834 accepted. Due...

  4. Medidas antropométricas segundo aptidão cardiorrespiratória em militares da ativa, Brasil Anthropometry and cardiorespiratory fitness of military men in active duty, Brazil

    Directory of Open Access Journals (Sweden)

    Eduardo de Almeida Magalhães Oliveira

    2008-04-01

    Full Text Available OBJETIVO: Analisar as diferenças no índice de massa corporal (IMC e no perímetro da cintura segundo a aptidão cardiorrespiratória em militares do sexo masculino. MÉTODOS: A amostra constituiu-se de 50.523 homens da ativa do exército brasileiro. Os dados antropométricos (massa corporal, estatura e perímetro da cintura e de consumo máximo de oxigênio (VO2max, estimado por meio do teste de corrida de 12 minutos, foram obtidos no teste de aptidão física do ano 2001. RESULTADOS: A idade variou de 18 a 52 anos, porém foi composta em sua maioria por indivíduos jovens (média + DP = 25,8 + 6,6 anos de idade. A faixa de aptidão cardiorrespiratória variou de 22,2 a 82,5 mL O2.kg-1.min-1. Os valores médios do perímetro da cintura foram significativamente menores nos grupos de melhor aptidão cardiorrespiratória, quando comparados com os grupos com menor aptidão (pOBJECTIVE: To analyze differences in body mass index (BMI and waist circumference according to cardiorespiratory fitness in active military men. METHODS: The study sample comprised 50,523 active military men of the Brazilian army. Anthropometric measures (body mass, height, and waist circumference and maximal oxygen consumption (VO2max information, estimated in a 12-min run, were obtained in a fitness test in 2001. RESULTS: Subjects' age ranged between 18 and 52 years, but most were young (mean + SD 25.8 + 6.6 years. Cardiorespiratory fitness varied from 22.2 to 82.5 mL.O2.kg-1.min-1. Waist circumference mean values were significantly lower in those subjects in the highest fitness level compared to those in the lowest level (p<0.001 even after adjusting for age, BMI, and both together. CONCLUSIONS: For the same BMI, military men with better cardiorespiratory fitness have significantly lower waist circumference measures compared to those with lower fitness. These findings suggest that military with better physical fitness have lower abdominal fat accumulation.

  5. Integrated Resistance and Aerobic Training Maintains Cardiovascular and Skeletal Muscle Fitness During 14 Days of Bed Rest

    Science.gov (United States)

    Ploutz-Snyder, Lori; Goetchius, Elizabeth; Crowell, Brent; Hackney, Kyle; Wickwire, Jason; Ploutz-Snyder, Robert; Snyder, Scott

    2012-01-01

    Background: Known incompatibilities exist between resistance and aerobic training. Of particular importance are findings that concurrent resistance and aerobic training reduces the effectiveness of the resistance training and limits skeletal muscle adaptations (example: Dudley & Djamil, 1985). Numerous unloading studies have documented the effectiveness of resistance training alone for the maintenance of skeletal muscle size and strength. However the practical applications of those studies are limited because long ]duration crew members perform both aerobic and resistance exercise throughout missions/spaceflight. To date, such integrated training on the International Space Station (ISS) has not been fully effective in the maintenance of skeletal muscle function. Purpose: The purpose of this study was to evaluate the efficacy of high intensity concurrent resistance and aerobic training for the maintenance of cardiovascular fitness and skeletal muscle strength, power and endurance over 14 days of strict bed rest. Methods: 9 subjects (8 male and 1 female; 34.5 +/- 8.2 years) underwent 14 days of bed rest with concurrent training. Resistance and aerobic training were integrated as shown in table 1. Days that included 2 exercise sessions had a 4-8 hour rest between exercise bouts. The resistance training consisted of 3 sets of 12 repetitions of squat, heel raise, leg press and hamstring curl exercise. Aerobic exercise consisted of periodized interval training that included 30 sec, 2 min and 4 min intervals alternating by day with continuous aerobic exercise.

  6. Prediction of Cardiorespiratory Fitness by the Six-Minute Step Test and Its Association with Muscle Strength and Power in Sedentary Obese and Lean Young Women: A Cross-Sectional Study.

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    Lívia Pinheiro Carvalho

    Full Text Available Impaired cardiorespiratory fitness (CRF is a hallmark characteristic in obese and lean sedentary young women. Peak oxygen consumption (VO2peak prediction from the six-minute step test (6MST has not been established for sedentary females. It is recognized that lower-limb muscle strength and power play a key role during functional activities. The aim of this study was to investigate cardiorespiratory responses during the 6MST and CPX and to develop a predictive equation to estimate VO2peak in both lean and obese subjects. Additionally we aim to investigate how muscle function impacts functional performance. Lean (LN = 13 and obese (OB = 18 women, aged 20-45, underwent a CPX, two 6MSTs, and isokinetic and isometric knee extensor strength and power evaluations. Regression analysis assessed the ability to predict VO2peak from the 6MST, age and body mass index (BMI. CPX and 6MST main outcomes were compared between LN and OB and correlated with strength and power variables. CRF, functional capacity, and muscle strength and power were lower in the OB compared to LN (<0.05. During the 6MST, LN and OB reached ~90% of predicted maximal heart rate and ~80% of the VO2peak obtained during CPX. BMI, age and number of step cycles (NSC explained 83% of the total variance in VO2peak. Moderate to strong correlations between VO2peak at CPX and VO2peak at 6MST (r = 0.86, VO2peak at CPX and NSC (r = 0.80, as well as between VO2peak, NSC and muscle strength and power variables were found (p<0.05. These findings indicate the 6MST, BMI and age accurately predict VO2peak in both lean and obese young sedentary women. Muscle strength and power were related to measures of aerobic and functional performance.

  7. Aptidão cardiorrespiratória e associações com fatores de risco cardiovascular em adolescentes The association between cardiorespiratory fitness and cardiovascular risk in adolescents

    Directory of Open Access Journals (Sweden)

    Anabel N. Rodrigues

    2007-10-01

    the measure of preference for expressing cardiorespiratory fitness for the purposes of surveys of physical activity, due to its greater objectivity and lower propensity to errors. Studies indicate that this measure is better correlated with cardiovascular diseases. This paper proposes to relate cardiovascular risk factors in adolescents with their level of cardiorespiratory fitness. METHODS: The study enrolled 380 schoolchildren, 177 boys and 203 girls (10 to 14 years old, who were divided into two groups according to their cardiorespiratory fitness. Anthropometric assessment was carried out, hemodynamic measurements (arterial pressure and heart rate were taken, cardiopulmonary exercise testing was performed and biochemical tests were run (triglycerides, total and partial cholesterol. RESULTS: Among the boys, significant differences were observed between boys defined as "weak" and those classed as "not weak" in terms of baseline heart rate, maximum oxygen uptake, body mass index and triglycerides. Among the girls, significant differences were detected between baseline heart rates, maximum oxygen uptake and body mass indices. In both sexes, the group classified as "weak" exhibited a significantly greater number of overweight individuals that the "not weak" group (x² = 25.242; p = 0.000; x² = 12.683; p = 0.000, for boys and girls, respectively. A significant association between cardiorespiratory fitness and triglycerides (x² = 3.944; p = 0.047 was observed among the boys only. CONCLUSIONS: A low level of cardiorespiratory fitness appears to have a negative influence on cardiovascular risk factors among adolescents, especially with relation to overweight in both sexes and to biochemical profile in the male sex, providing evidence of the need for early preventative interventions.

  8. Uma análise entre índices pressóricos, obesidade e capacidade cardiorrespiratória em escolares Comparison analysis of blood pressure, obesity, and cardio-respiratory fitness in schoolchildren

    Directory of Open Access Journals (Sweden)

    Miria Suzana Burgos

    2010-06-01

    diseases, especially obesity, hypertension, and diabetes mellitus. Early intervention can prevent the development of these complications. OBJECTIVE: To determine the presence of cardiovascular risk (obesity and hypertension in schoolchildren and its potential interactions with cardio-respiratory fitness. METHODS: This was a cross-sectional study conducted in a stratified cluster sample of 1,666 schoolchildren, aged between 7 and 17 years, 873 (52.4% of them male and 793 (47.6% of them female. The following variables were evaluated: systolic blood pressure (SBP, diastolic blood pressure (DBP, body mass index (BMI, body fat percentage (BF %, and cardio-respiratory fitness. SBP and DBP were correlated with waist circumference (WC, waist-hip ratio (WHR, sum of skin folds (ΣSF, and cardio-respiratory fitness. RESULTS: A BMI assessment of the students showed that 26.7% of them were overweight or obese, and 35.9% had body fat percentage over moderately high. As to blood pressure, we found that 13.9% and 12.1% of the students were borderline or hypertensive, for SBP and DBP, respectively. There was an association among hypertension, obesity, and cardio-respiratory fitness. There was a significant correlation of SBP and DBP with all variables, and also a weak to moderate correlation with age, weight, height, BMI, and waist circumference. CONCLUSION: The presence of hypertension associated with obesity and its effects on cardio-respiratory fitness stress the importance of recommending, since childhood, a more active and healthy lifestyle.

  9. Fitness

    Science.gov (United States)

    ... gov home http://www.girlshealth.gov/ Home Fitness Fitness Want to look and feel your best? Physical ... are? Check out this info: What is physical fitness? top Physical fitness means you can do everyday ...

  10. Association between Changes in Muscle Quality with Exercise Training and Changes in Cardiorespiratory Fitness Measures in Individuals with Type 2 Diabetes Mellitus: Results from the HART-D Study.

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    Martin Sénéchal

    Full Text Available Type 2 diabetes mellitus (T2DM is associated with a reduction in muscle quality. However, there is inadequate empirical evidence to determine whether changes in muscle quality following exercise are associated with improvement in cardiorespiratory fitness (CRF in individuals with T2DM. The objective of this study was to investigate the association between change in muscle quality following a 9-month intervention of aerobic training (AT, resistance training (RT or a combination of both (ATRT and cardiorespiratory fitness (CRF in individuals with T2DM.A total of 196 participants were randomly assigned to a control, AT, RT, or combined ATRT for a 9-months intervention. The exposure variable was change in muscle quality [(Post: leg muscle strength/leg muscle mass-[(Pre: leg muscle strength/leg muscle mass]. Dependent variables were change in CRF measures including absolute and relative VO2peak, and treadmill time to exhaustion (TTE and estimated metabolic equivalent task (METs.Continuous change in muscle quality was independently associated with change in absolute (β = 0.015; p = 0.019 and relative (β = 0.200; p = 0.005 VO2peak, and TTE (β = 0.170; p = 0.043, but not with estimated METs (p > 0.05. A significant trend was observed across tertiles of change in muscle quality for changes in absolute (β = 0.050; p = 0.005 and relative (β = 0.624; p = 0.002 VO2peak following 9 months of exercise training. No such association was observed for change in TTE and estimated METs (p > 0.05.The results from this ancillary study suggest that change in muscle quality following exercise training is associated with a greater improvement in CRF in individuals with T2DM. Given the effect RT has on increasing muscle quality, especially as part of a recommended training program (ATRT, individuals with T2DM should incorporate RT into their AT regimens to optimize CRF improvement.Clinicaltrials.gov NCT00458133.

  11. The relationship between cell phone use, physical and sedentary activity, and cardiorespiratory fitness in a sample of U.S. college students

    OpenAIRE

    Lepp, Andrew; Jacob E. Barkley; SANDERS, GABRIEL J.; Rebold, Michael; Gates, Peter

    2013-01-01

    Background Today’s cell phones increase opportunities for activities traditionally defined as sedentary behaviors (e.g., surfing the internet, playing video games). People who participate in large amounts of sedentary behaviors, relative to those who do not, tend to be less physically active, less physically fit, and at greater risk for health problems. However, cell phone use does not have to be a sedentary behavior as these devices are portable. It can occur while standing or during mild-to...

  12. A preseason cardiorespiratory profile of dancers in nine professional ballet and modern companies.

    Science.gov (United States)

    Bronner, Shaw; Ojofeitimi, Sheyi; Lora, Jennifer Bailey; Southwick, Heather; Kulak, Michelina Cassella; Gamboa, Jennifer; Rooney, Megan; Gilman, Greg; Gibbs, Richard

    2014-01-01

    While studies have investigated the physical demands of dance in terms of cardiorespiratory fitness, there are no recent comparisons of cardiorespiratory response to exercise among professional dancers of different genres. Our purpose was to: 1. develop a cardiorespiratory profile of professional dancers; 2. investigate differences in peak and recovery heart rate (HR) between professional modern and ballet dancers using an accelerated 3-minute step test; 3. demonstrate the relationship between cardiorespiratory variables; and 4. investigate the effects of company and work variables on the dancers' cardiorespiratory profiles. We hypothesized greater cardiorespiratory fitness in modern dancers than in ballet dancers, due to the nature of their repertory. Furthermore, we hypothesized that company profiles would reflect differences in work variables. Two hundred and eleven dancers (mean age 24.6 ± 4.7) from nine companies (two modern and seven ballet) performed a 3-minute step test. Demographics, height, mass, blood pressure (BP), smoking history, and resting peak and recovery HR were recorded. Body mass index (BMI) and fitness category were calculated. Independent t-tests were used to compare differences in demographics and cardiorespiratory variables due to genre, MANOVA were conducted to compare differences due to company, and correlations were calculated to determine the relationships between cardiorespiratory variables (p Modern dancers demonstrated higher mass and BMI, lower BP, lower resting HR and HR recovery, and a higher percentage were categorized as "fit" compared to ballet dancers (p < 0.03). There were differences between companies in age, experience, BMI, BP, resting, peak, and recovery HR, and fitness category (p < 0.001). The differences in cardiorespiratory fitness levels that may be related to rigor of repertory, rehearsal and performance seasons, or off-season exercise training are discussed. Results support the need for comprehensive physical

  13. Physical activity, fitness, and gray matter volume

    OpenAIRE

    Erickson, Kirk I.; Leckie, Regina L; Weinstein, Andrea M.

    2014-01-01

    In this review we explore the association between physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher cardiorespiratory fitness levels are routinely associated with greater gray matter volume in the prefrontal cortex and hippocampus, and less consistently in other regions. We also conclude that physical activity is associated with greater gray matter volume in the same regions that are associated with cardiorespiratory fitn...

  14. Taekwondo training and fitness in female adolescents.

    Science.gov (United States)

    Kim, Hyun-Bae; Stebbins, Charles L; Chai, Joo-Hee; Song, Jong-Kook

    2011-01-01

    In this study, we determined the specificity of a low frequency taekwondo training programme on physical fitness levels in adolescent females who receive limited physical education instruction (i.e. 2 days per week). Major components of physical fitness assessed were: skeletal muscle fitness (hand grip strength, bent arm hang, standing long jump, and isokinetic strength), flexibility (sit-and-reach test), speed and agility (10 × 5-m shuttle run), and cardiovascular fitness (VO(2max) and 20-m shuttle run). Changes in body composition were also assessed (dual X-ray absorptiometry, DXA). Participants were divided into two groups, a taekwondo training group (n = 21), which trained 50 min a day, 2 days per week for 12 weeks, and a control group (n = 10). Taekwondo training improved isokinetic strength, standing long jump, and sit-and-reach performance. Body fat mass and percent body fat were reduced. No changes in grip strength, bent arm hang time, speed and agility, or cardiorespiratory fitness were observed. Results indicate that low frequency taekwondo training in adolescent females produces beneficial changes in skeletal muscle fitness, flexibility, and body composition in a relatively short period of time. Consequently, this specific type of training can be useful to female adolescents in structured school environments where physical education classes are limited and there is little free time for physical activity.

  15. 大学生体力活动、心肺耐力与抑郁风险关系的纵向研究%Longitudinal study of physical activity,cardiorespiratory fitness and risk of depres-sion among college students

    Institute of Scientific and Technical Information of China (English)

    李秋利; 关尚一; 张少生

    2015-01-01

    Objective:To determine the relations between physical activity,cardiorespiratory fitness and depressive symptoms among college students.Methods:The sample included 518 males and 549 females.International Physical Activity Questionnaire (IPAQ),fitness test and Center for Epidemi-ologic Studies Depression Scale(CES -D)were used to measure physical activity,cardiorespiratory fitness and depression respectively for 3 times in 2 years longitude study.Latent Growth Modeling and Logistic regression were used to assess the data.Results:After adjustment for age,BMI,time between visits,parents'education level,family financial condition and lung capacity,each 10MET-min /d decline in physical activity level,increased the odds of depression risk by approximately 1. 1% in men and 2.1% in women.Each 10 seconds increase in cardiorespiratory fitness test (1000 m run for men and 800 m run for women),increased the odds of depression risk by approximately 1.5% in men and 6.3% in women.Conclusion:There was a close relation between physical activi-ty,cardiorespiratory fitness and depressive symptoms among college students.To improve physical activity and cardiorespiratory fitness can decrease depression risk of college students.%目的:探讨大学生体力活动、心肺耐力、抑郁风险三者之间的关系。方法:采用国际体力活动问卷(IPAQ)、体质健康测试和抑郁筛选量表(CES -D 量表)对1067名在校大学生(其中男生518人,女生549人)体力活动、体质健康水平和抑郁水平进行了评估,研究采用纵向研究设计,追踪测量持续两年时间,每隔1年测量一次,采用潜变量增长模型和 Logistic 回归对所测得的数据进行分析。结果发现,经过年龄、BMI、独生子女、父母文化程度、自评家庭经济、肺活量等可能的混杂因素校正后,体力活动水平每下降10 MET -min /d 可以引起男生抑郁事件的发生风险率增加1.1%(OR =1.011)

  16. Aptidão cardiorrespiratória, perfil lipídico e metabólico em adolescentes obesos e não-obesos Cardiorespiratory fitness, lipid and metabolic profile in obese and non-obese adolescents

    Directory of Open Access Journals (Sweden)

    Neiva Leite

    2009-09-01

    Full Text Available O objetivo deste estudo foi investigar a relação entre o consumo máximo de oxigênio, perfil lipídico e metabólico em meninas e meninos obesos e não-obesos. Estudo transversal, descritivo e correlacional. A amostra foi composta por 91 obesos e 30 não-obesos, dos 10 aos 16 anos. Avaliou-se o índice de massa corporal (IMC e a circunferência abdominal (CA. A aptidão cardiorrespiratória foi avaliada de forma direta através da análise do consumo máximo de oxigênio (O2max. Determinaram-se níveis de colesterol total (CT, lipoproteína de alta densidade (HDL-C, lipoproteína de baixa densidade (LDL-C, triglicérides (TG, glicemia e insulinemia após 12 horas de jejum. Analisaram-se os dados pelo teste "t" de student e correlação parcial controlada pela idade, com um nível de significância de pO2max com o IMC (r = -0,540; p O2max com a CT, a fração LDL-C e a glicemia.O menor VO2max correlacionou com maiores adiposidade, TG e insulinemia, bem como redução de HDL. O O2max não correlacionou com o CT, LDL-C e glicemia, sugerindo a importância do controle genético sobre estas variáveis e um menor tempo de influência do sedentarismo na população infanto-juvenil.The aim this study was investigates the relationship between maximum oxygen consumption, lipid and metabolic profile in obese and non-obese girls and boys. Transversal, descriptive and correlational study. 91 obese and 30 non-obese subjects participated, with 10 to 16 years. There were well overall adiposity by body mass index (BMI, and central adiposity by waist circumference (WC. The cardiorespiratory fitness was assessed by a direct analysis of maximum oxygen consumption (O2max. Are determined levels of total cholesterol (TC, high density lipoprotein (HDL-C, low density lipoprotein (LDL-C, triglycerides (TG, glucose and insulin after 12 hours of fasting. We analyzed the data by "t" student`s test and partial correlation controlled for age, with a significance level of p

  17. Pontos de corte para a aptidão cardiorrespiratória e a triagem de fatores de risco para doenças cardiovasculares na infância Cardiorespiratory fitness cut offs points and cardiovascular risk factors screening at infancy

    Directory of Open Access Journals (Sweden)

    Gabriel Gustavo Bergmann

    2010-10-01

    Full Text Available O principal objetivo deste estudo foi analisar a validade e propor novos pontos de corte para aptidão cardiorrespiratória de escolares de sete a 12 anos de idade. A amostra foi constituída por 1.413 escolares. A aptidão cardiorrespiratória foi medida através do teste de corrida/caminhada de nove minutos. O colesterol total e as pressões arterial sistólica e diastólica foram medidas e através delas foram criadas referências de fatores de risco para doenças cardiovasculares. Através da curva receiver operating characteristic entre a aptidão cardiorrespiratória e as referências de fatores de risco para doenças cardiovasculares foram identificados os valores dos pontos de corte. Adicionalmente foi utilizada a análise bivariada seguida do cálculo de razão de chances (odds ratio-OR para identificar quanto os indivíduos que não atenderam os pontos de corte propostos tinham a mais de chance de apresentar fatores de risco para doenças cardiovasculares. Os resultados indicaram que, dentre as propostas analisadas, a que foi sugerida neste estudo apresentou melhores ajustamentos entre sensibilidade e especificidade. Os resultados da análise bivariada mostraram que indivíduos que não atenderam os pontos de corte propostos têm maiores chances de apresentarem fatores de risco para doenças cardiovasculares.The main objective of the study was to analyze and propose news cardiorespiratory fitness cut offs points for 7 to 12-year old school students. The sample was composed of 1,413 students. Cardiorespiratory fitness was measured by the 9-minutes walking/running test. Total cholesterol and systolic and diastolic blood pressure were measured and with their results cardiovascular risk factors reference were designed. The Receiver Operating Characteristic curve between cardiorespiratory fitness and cardiovascular risk factors reference identified the cut offs point values. The bivariate analysis and odds ratio (OR calculation was used to

  18. Impact of Resistance Circuit Training on Neuromuscular, Cardiorespiratory and Body Composition Adaptations in the Elderly

    Science.gov (United States)

    Romero-Arenas, Salvador; Martínez-Pascual, Miryam; Alcaraz, Pedro E.

    2013-01-01

    Declines in maximal aerobic power and skeletal muscle force production with advancing age are examples of functional declines with aging, which can severely limit physical performance and independence, and are negatively correlated with all cause mortality. It is well known that both endurance exercise and resistance training can substantially improve physical fitness and health-related factors in older individuals. Circuit-based resistance training, where loads are lifted with minimal rest, may be a very effective strategy for increasing oxygen consumption, pulmonary ventilation, strength, and functional capacity while improving body composition. In addition, circuit training is a time-efficient exercise modality that can elicit demonstrable improvements in health and physical fitness. Hence, it seems reasonable to identify the most effective combination of intensity, volume, work to rest ratio, weekly frequency and exercise sequence to promote neuromuscular, cardiorespiratory and body composition adaptations in the elderly. Thus, the purpose of this review was to summarize and update knowledge about the effects of circuit weight training in older adults and elderly population, as a starting point for developing future interventions that maintain a higher quality of life in people throughout their lifetime. PMID:24124631

  19. Efeitos do treinamento neuromuscular na aptidão cardiorrespiratória e composição corporal de atletas de voleibol do sexo feminino Effects of the neuromuscular training in the cardiorespiratory fitness and body composition of female volleyball athletes

    Directory of Open Access Journals (Sweden)

    Ricardo Adamoli Simões

    2009-08-01

    Full Text Available As respostas do organismo humano submetido a estímulos diversos, mensuradas através de parâmetros de performance, têm sido objeto de estudo a fim de aprimorar os métodos de treinamento. O objetivo deste estudo foi investigar os efeitos do treinamento neuromuscular na capacidade cardiorrespiratória e composição corporal de atletas de voleibol. Foram avaliadas 11 mulheres, antes e após 12 semanas de treinamento, referente à fase preparatória do ciclo anual de treinamento. O protocolo experimental constou de avaliação da composição corporal (percentual de gordura, massa magra e a gordura corporal e da aptidão cardiorrespiratória por meio de ergoespirometria em esteira rolante com protocolo contínuo e carga crescente, na qual se determinaram o consumo máximo de oxigênio, a frequência cardíaca máxima, o limiar anaeróbio, a frequência cardíaca do limiar anaeróbio e a velocidade do limiar anaeróbio. O treinamento teve frequência de cinco dias por semana dividido em duas sessões: uma de treinamento de força e outra de treinamento técnico e tático. Após o período estudado ocorreram aumentos (p The responses of the human body submitted to several stimuli measured by performance parameters have been object of studies in order to improve training methods. The aim of this study was to investigate the effects of the neuromuscular training in the cardiorespiratory fitness and body composition of volleyball athletes. Eleven women were assessed before and after 12 weeks of training, concerning the preparatory phase of the annual training cycle. The experimental protocol consisted of assessment of the body composition (fat percentage, lean mass and body fat and of the cardiorespiratory fitness through ergospirometry on treadmill with continuous protocol and increasing load, in which the oxygen maximal uptake, maximum heart rate, anaerobic threshold, heart rate threshold and anaerobic threshold velocity were determined. The

  20. A Small-scale Cross-sectional Study for the Assessment of Cardiorespiratory Fitness in Relation to Body Composition and Morphometric Characters in Fishermen of Araku Valley, Andhra Pradesh, India

    Directory of Open Access Journals (Sweden)

    Pallav Sengupta

    2014-01-01

    Conclusions: Findings of this small-scale population-based study indicated that health and physical fitness of young fishermen is under the influence of both occupational workload and nutritional status, as found by body composition and morphometric characters.

  1. Cardiorespiratory Responses and Prediction of Peak Oxygen Uptake during the Shuttle Walking Test in Healthy Sedentary Adult Men

    OpenAIRE

    Camila D C Neves; Ana Cristina Rodrigues Lacerda; Lage, Vanessa K. S.; Lima, Liliana P.; Fonseca, Sueli F.; Núbia C. P. Avelar; Teixeira, Mauro M; Mendonça, Vanessa A

    2015-01-01

    BACKGROUND: The application of the Shuttle Walking Test (SWT) to assess cardiorespiratory fitness and the intensity of this test in healthy participants has rarely been studied. This study aimed to assess and correlate the cardiorespiratory responses of the SWT with the cardiopulmonary exercise testing (CEPT) and to develop a regression equation for the prediction of peak oxygen uptake (VO2 peak) in healthy sedentary adult men. METHODS: In the first stage of this study, 12 participants underw...

  2. Physical Work Demands and Fitness

    DEFF Research Database (Denmark)

    Larsen, Mette Korshøj

    . The effects were evaluated with objective physiological or diurnal data in an intention-to-treat analysis using multi-adjusted mixed models. The results indicated that the intervention led to several improvements in risk factors for cardiovascular disease, e.g. enhanced cardiorespiratory fitness, reduced...... exposed to high relative aerobic workloads obtained more pronounced increases of resting and 24-hour ambulatory blood pressure, an unaltered cardiorespiratory fitness and a reduced sleeping heart rate. The enhanced resting and 24-hour ambulatory blood pressure may be explained as a potential...

  3. Efeitos de exercícios aquáticos sobre a aptidão cardiorrespiratória e a pressão arterial em hipertensas Effects of aquatic exercise on cardiorespiratory fitness and blood pressure in hypertensive women

    Directory of Open Access Journals (Sweden)

    Lisiane Piazza

    2008-09-01

    Full Text Available O estudo visou avaliar a influência de um programa de exercícios aquáticos sobre a aptidão cardiorrespiratória e a pressão arterial em mulheres hipertensas. Dez hipertensas participaram do programa de exercícios aquáticos - aeróbicos, de fortalecimento, alongamento e relaxamento - duas vezes por semana durante 7 semanas, totalizando 14 sessões. Foram avaliadas pelo teste de esforço cardiorrespiratório antes e após o desenvolvimento do programa. A pressão arterial foi mensurada ao repouso e aos 10, 20 e 30 minutos após o exercício em cada sessão. As variáveis cardiorrespiratórias não apresentaram alterações significativas após o programa, tanto dos valores de limiar de anaerobiose quanto os do pico de esforço. As pressões arteriais sistólica, diastólica e média de repouso permaneceram estáveis no decorrer do programa. Entretanto, no período pós-exercício, os níveis da pressão arterial sistólica (PAS e média (PAM foram significativamente menores, quando comparados aos valores pré-exercício: houve redução média de 6,43 mmHg da PAS e 3,08 mmHg da PAM aos 30 minutos pós-exercício. Assim, o programa de exercícios aquáticos proposto não promove ganho aeróbico efetivo, mas os resultados sugerem que exercícios aquáticos como os propostos, em intensidade próxima ao limiar de anaerobiose, desencadeiam redução dos níveis de pressão arterial no período pós-exercício, em mulheres hipertensas.The aim of this study was to assess the influence of an aquatic exercise program on cardiorespiratory fitness and blood pressure in hypertensive women. Ten hypertensive women took part in the study. The program consisted of aquatic aerobic, strengthening, and stretching exercises in intensity near the anaerobic threshold, besides relaxation, twice a week during 7 weeks, totalling 14 sessions. They were assessed by cardiorespiratory exercise testing before and after program development. Blood pressure was measured at

  4. Lactate clearance in cardiorespiratory emergency

    Directory of Open Access Journals (Sweden)

    Serena Greco

    2007-08-01

    Full Text Available Early goal directed therapy has been found to improve prognosis in septic patients, if the therapeutic goal is achieved within the first six hours. The aim of our study is to demonstrate that in patients with acute cardiorespiratory failure, rapid (within 2 hours lactate clearance can help define patients’ prognosis. 67 consecutive patients, admitted to our 16-bed Emergency Medicine ward for acute cardiorespiratory failure (age 75,9 ± 9,8 (APACHE II score 19,0 ± 4,1, were included in the study. Blood lactate concentration was read at admission and after 2, 6 and 24 hours. We evaluated mortality at seven days and the use of orotracheal intubation (patients with negative outcome vs. discharge or transfer to a non-emergency ward with subsequent discharge (patients with negative outcome. Lactate concentration at admission was 4,6 ± 2,5 mmol/l; lactate clearance (% at 2 hours was 40,4 ± 32,1 in patients with a positive outcome and –8,3 ± 5,0 in patients with a negative outcome (p < 0,05. Lactate clearance at 2 hours < 25% is correlated to a negative outcome with an 84,2% sensitivity and a 79,2% specificity. The positive predictive value was 61,5% and the negative predictive value was 92,2%. Systematic lactate clearance monitoring can be used in cases of acute cardiorespiratory insufficiency to identify patients with a high risk of negative outcome. In our study, low clearance at two hours was associated with an increase in mortality and/or the need for orotracheal intubation. Conversely, a clearance at two hours of > 25% in most cases confirms the therapeutic strategy undertaken. Serial evaluation of blood lactate concentration may therefore be useful in guiding treatment strategies.

  5. Imagem corporal, estado nutricional, força de resistência abdominal e aptidão cardiorrespiratória de crianças e adolescentes praticantes de esportes Imagen corporal, estado nutricional, fuerza de resistencia abdominal y aptitud cardiorrespiratoria de niños y adolescentes practicantes de deportes Body image, nutritional status, abdominal strength, and cardiorespiratory fitness in children and adolescents practicing sports

    Directory of Open Access Journals (Sweden)

    Alexandre Schubert

    2013-03-01

    image, abdominal strength resistance, and cardiorespiratory fitness. The variables were assessed on the same day following a standardized order. In order to verify relationships between variables, the chi-square test was used. Afterwards, the binary logistic regression was applied to identify the magnitude of the associations, considering p<0.05 as significant. RESULTS: Association was found between body image and body mass index (p=0.001, abdominal strength resistance (p=0.005 and cardiorespiratory fitness (p=0.001. The Odds Ratio for presenting the body image insatisfaction for those who have not achieved the expected values for the health criteria in abdominal strength resistance and cardiorespiratory fitness were 2.14 and 2.42 times respectively, and for those with overweight and obesity, 2.87 times. CONCLUSIONS: Insatisfaction with body image is associated with body mass index and also with physical fitness, abdominal strength resistance, and cardiorespiratory fitness variables.

  6. Effect of robotic gait training on cardiorespiratory system in incomplete spinal cord injury

    NARCIS (Netherlands)

    Hoekstra, Femke; van Nunen, Michiel P. M.; Gerrits, Karin H. L.; Stolwijk-Swuste, Janneke M.; Crins, Martine H. P.; Janssen, Thomas W. J.

    2013-01-01

    The objectives in this study were to investigate the effect of robot-assisted gait training on cardiorespiratory fitness in subjects with motor incomplete spinal cord injury and document the exercise intensity of robotic walking in comparison with the recommended guidelines. Ten patients followed a

  7. Cardiorespiratory responses to moderate exercise and determination of aerobic power in first year medical students

    Directory of Open Access Journals (Sweden)

    Subha Kavundapadi Chandrasekaran

    2016-06-01

    Conclusions: Aerobic power or VO2max or physical work capacity which involves a full functional support from cardiorespiratory and metabolic pathways is an appropriate test to study cardiopulmonary fitness. Implication: Astrand 6 minutes cycle test can be used for screening measures before joining in a job or sports training where physical fitness is needed. [Int J Res Med Sci 2016; 4(6.000: 1993-1996

  8. Suryanamaskar: An equivalent approach towards management of physical fitness in obese females

    Directory of Open Access Journals (Sweden)

    Komal A Jakhotia

    2015-01-01

    Conclusions: All three methods were effective in weight and physical fitness management. CT and SN were more effective in improving cardio-respiratory fitness and upper limb muscle endurance while only SN was effective in improving body flexibility.

  9. Cross sectional analysis of the association between mode of school transportation and physical fitness in children and adolescents

    DEFF Research Database (Denmark)

    Ostergaard, Lars; Kolle, Elin; Steene-Johannessen, Jostein;

    2013-01-01

    To investigate the associations between body composition, cardiorespiratory and muscular fitness in relation to travel mode to school in children and adolescents.......To investigate the associations between body composition, cardiorespiratory and muscular fitness in relation to travel mode to school in children and adolescents....

  10. Metabolismo de glicose em gêmeos monozigóticos discordantes para aptidão cardiorrespiratória Metabolismo de glucosa en gemelos monocigóticos discordantes para aptitud cardiorrespiratoria Glucose metabolism in discordant monozygotic twins for cardiorespiratory fitness

    Directory of Open Access Journals (Sweden)

    Marcos Roberto Queiroga

    2013-03-01

    L.kg-1.min-1 y fueron divididos en dos grupos, de alta y baja aptitud. Los grupos fueron comparados a partir de la prueba pareada de Wilcoxon, teniendo en vista la asimetría de los datos. RESULTADOS: En promedio, los gemelos del grupo de alta aptitud presentaron consumo máximo de oxígeno el 17% superior (13,5±3,7mL.kg-1.min-1 a sus hermanos menos aptos. No hubo diferencia entre los grupos para las concentraciones de insulina (36,5±34,6 versus 25,3±13,7mg/dL; pOBJECTIVE: To determine if glucose and insulin concentrations are regulated by cardiorespiratory fitness (VO2max regardless of their genetic effects. METHODS: This cross-sectional study enrolled 38 pairs of young monozygotic twins (11 to 18 years-old. All subjects underwent a progressive maximal exercise test on a treadmill to determine the VO2max with gas exchange analysis (MedGraphics VO2000® - Medical Graphics Corp., St. Paul, MN. Blood samples were drawn after fasting to determine glucose and insulin levels. Monozygosity was confirmed by genotyping 15 informative genetic markers. Nine pairs had at least 10mL.kg-1.min-1 difference in VO2max and were divided into the more and less active group, according to their VO2max. Mean differences between more and less active groups were evaluated by Wilcoxon's test for paired data. RESULTS: On average, twins from the more active group presented a 17% (13.5±3.7mL.kg-1.min-1 higher VO2max compared to their less active siblings. No significant differences were observed between the groups for fasting insulin (36.5±34.6 versus 25.3±13.7mg/dL; p<0.813. However, the more active twins had lower fasting glucose than the less active ones (82.9±7.3 versus 86.7±7.6mg/dL; p<0.010. CONCLUSIONS: In this case-control study (discordant monozygotic twins, the less active co-twins were characterized by higher fasting plasma glucose levels. This implies that poor cardiorespiratory fitness can be associated with defective glucose metabolism regardless of genetic factors.

  11. Cardiorespiratory Coupling in Health and Disease

    OpenAIRE

    Garcia, Alfredo J.; Koschnitzky, Jenna E.; Dashevskiy, Tatiana; Ramirez, Jan-Marino

    2013-01-01

    Cardiac and respiratory activities are intricately linked both functionally as well as anatomically through highly overlapping brainstem networks controlling these autonomic physiologies that are essential for survival. Cardiorespiratory coupling (CRC) has many potential benefits creating synergies that promote healthy physiology. However, when such coupling deteriorates autonomic dysautonomia may ensue. Unfortunately there is still an incomplete mechanistic understanding of both normal and p...

  12. Effect of robotic gait training on cardiorespiratory system in incomplete spinal cord injury

    Directory of Open Access Journals (Sweden)

    Femke Hoekstra, MSc

    2014-02-01

    Full Text Available The objectives in this study were to investigate the effect of robot-assisted gait training on cardiorespiratory fitness in subjects with motor incomplete spinal cord injury and document the exercise intensity of robotic walking in comparison with the recommended guidelines. Ten patients followed a 24-session training program with a robotic gait orthosis in addition to physiotherapy sessions completed within 10 to 16 wk. Cardiorespiratory fitness was determined in a graded arm crank exercise test before and after the training program. To assess the intensity of robot-assisted walking, oxygen consumption (VO2 and heart rate (HR were measured during a training session early in and at the end of the training program, and exercise intensity measures (percentage of VO2 reserve [%VO2R], percentage of HR reserve [%HRR], and metabolic equivalents [METs] were calculated. Whereas no changes were found in peak VO2, the resting and submaximal HR at a constant work load were significantly lower after training. Most subjects exercised at low intensity (3.0 METs. In spite of the low exercise intensity of the training program and no changes in peak VO2, robot-assisted gait training induced some improvement in cardiorespiratory fitness, as suggested by lower resting and submaximal HR values.

  13. Distribution of Abdominal Obesity and Fitness Level in Overweight and Obese Korean Adults

    OpenAIRE

    Sue Kim; Ji-Young Kim; Duk-Chul Lee; Hye-Sun Lee; Ji-Won Lee; Jeon, Justin Y.

    2014-01-01

    Background. Abdominal obesity and its relative distribution are known to differ in association with metabolic characteristics and cardiorespiratory fitness. This study aimed to determine an association between fitness level and abdominal adiposity in overweight and obese adults. Methods. 228 overweight and obese individuals were classified as either cardiorespiratory unfit or fit based on their recovery heart rate. Visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), the visceral...

  14. Low muscle fitness is associated with metabolic risk in youth

    DEFF Research Database (Denmark)

    Steene-Johannessen, Jostein; Anderssen, Sigmund A; Kolle, Elin;

    2009-01-01

    PURPOSE: To examine the independent associations of muscle fitness and cardiorespiratory fitness with clustered metabolic risk in youth. METHODS: In 2005-2006, a cohort of 9- and 15-yr-olds (N = 2818) was randomly selected from all regions of Norway. The participation rate was 89% and 74% among...... the 9-and 15-yr-olds, respectively. We assessed muscular strength by measuring explosive, isometric, and endurance strength. Cardiorespiratory fitness was measured directly as peak oxygen uptake during a cycle ergometry test. Risk factors included in the composite risk factor score (sum of z......-scores) were systolic blood pressure, triglyceride, high-density lipoprotein cholesterol, insulin resistance, and waist circumference. RESULTS: Muscle fitness was negatively associated with clustered metabolic risk, independent of cardiorespiratory fitness, and after adjustment for age, sex, and pubertal stage...

  15. Cardiorespiratory function associated with dietary nitrate supplementation

    OpenAIRE

    Bond, Vernon; Curry, Bryan H.; Adams, Richard G.; Millis, Richard M.; Georges E. Haddad

    2013-01-01

    The advent of medical nutrition therapy and nutritional physiology affords the opportunity to link diet to specific cardiovascular mechanisms, suggesting novel treatments for cardiovascular disease. This study tests the hypothesis that beetroot juice increases the plasma nitric oxide (NO) concentration, which is associated with improvements in cardiorespiratory function at rest and during submaximal aerobic exercise. The subjects were 12 healthy, young adult, normotensive African-American fem...

  16. Impact of Colored Light on Cardiorespiratory Coordination

    Directory of Open Access Journals (Sweden)

    Friedrich Edelhäuser

    2013-01-01

    Full Text Available Background. Light exposure to the eye can influence different physiological functions, for example, the suprachiasmatic nucleus (SCN. By affecting the autonomic nervous system, the SCN may influence the heart rate variability (HRV. Standardized colored light exposure alters HRV but the results are inconsistent. In this study we investigated the effects of nonstandardized red light (approx. 640 nm and blue (approx. 480 nm light (approx. 50 lx on cardiorespiratory coordination and HRV. Methods. 17 healthy subjects (7 males, age: 26.5 ± 6.2 years were exposed to the following sequence (10 minutes each: daylight-red light-daylight-blue light-daylight. Red and blue lights were created by daylight passing through colored glass panes. Spectral measures of HRV (LF: low frequency, HF: high frequency oscillations, and sympathovagal balance LF/HF and measures of cardiorespiratory coordination (HRR: heart respiration ratio, PCR: phase coordination ratio were analyzed. Results. The LF component increased and the HF component decreased after red light. Consequently, LF/HF increased after red light. Furthermore, during red light HRR and PCR confined to 4 : 1, that is, 4 heartbeats during one respiratory cycle. Conclusion. Nonstandardized red and blue lights are able to alter the autonomic control reflected by HRV as well as cardiorespiratory coordination.

  17. Fitness versus Fatness and Insulin Resistance in U.S. Adolescents

    OpenAIRE

    Cummings, Doyle M; DuBose, Katrina D.; Satomi Imai; Collier, David N.

    2010-01-01

    Background. The present study examined the relationship between insulin resistance and both waist circumference and cardiorespiratory fitness in U.S. adolescents. Methods. NHANES assessed a nationally representative sample of U.S. adolescents (12–18 yrs) between 1999–2002. Abdominal adiposity was estimated by waist circumference, overall adiposity by BMI, and cardiorespiratory fitness (maximal oxygen uptake (VO2max) from a treadmill exercise test). Insulin resistance was estimated from fastin...

  18. Effect of including fitness testing in preventive health checks on cardiorespiratory fitness and motivation

    DEFF Research Database (Denmark)

    Høj, Kirsten; Skriver, Mette Vinther; Hansen, Anne-Louise Smidt;

    2014-01-01

    Denne artikel beskriver studieprotokollen for et randomiseret kontrolleret studie, som skal undersøge effekten af at udføre konditests som en del af forebyggende helbredsundersøgelser sammenlignet med helbredsundersøgelser uden konditests. I Randers kommune tilbyder man i perioden 2012-2017 alle ...

  19. What Is the Relationship between Outdoor Time and Physical Activity, Sedentary Behaviour, and Physical Fitness in Children? A Systematic Review

    OpenAIRE

    Casey Gray; Rebecca Gibbons; Richard Larouche; Ellen Beate Hansen Sandseter; Adam Bienenstock; Mariana Brussoni; Guylaine Chabot; Susan Herrington; Ian Janssen; William Pickett; Marlene Power; Nick Stanger; Margaret Sampson; Tremblay, Mark S.

    2015-01-01

    The objective of this systematic review was to examine the relationship between outdoor time and: (1) physical activity, (2) cardiorespiratory fitness, (3) musculoskeletal fitness, (4) sedentary behaviour; or (5) motor skill development in children aged 3–12 years. We identified 28 relevant studies that were assessed for quality using the GRADE framework. The systematic review revealed overall positive effects of outdoor time on physical activity, sedentary behaviour, and cardiorespiratory fi...

  20. Cardio-Respiratory Coordination Increases during Sleep Apnea

    OpenAIRE

    Riedl, M.; Müller, A.; Kraemer, J. F.; Penzel, T; Kurths, J.; Wessel, N.

    2014-01-01

    Cardiovascular diseases are the main source of morbidity and mortality in the United States with costs of more than $170 billion. Repetitive respiratory disorders during sleep are assumed to be a major cause of these diseases. Therefore, the understanding of the cardio-respiratory regulation during these events is of high public interest. One of the governing mechanisms is the mutual influence of the cardiac and respiratory oscillations on their respective onsets, the cardio-respiratory coord...

  1. Exploring the Relationship between Adiposity and Fitness in Young Children

    DEFF Research Database (Denmark)

    Egebæk, Heidi Klakk; Fairchild, Timothy J; Heidemann, Malene;

    2016-01-01

    PURPOSE: High levels of cardiorespiratory fitness (CRF) may attenuate the association between excessive adiposity and the risks of cardiovascular and metabolic disease. The purpose of this study was to stratify children according to their BMI and adiposity (body fat percentage, BF%) and compare...

  2. Physical activity, fitness, and gray matter volume.

    Science.gov (United States)

    Erickson, Kirk I; Leckie, Regina L; Weinstein, Andrea M

    2014-09-01

    In this review, we explore the association among physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher cardiorespiratory fitness levels are routinely associated with greater gray matter volume in the prefrontal cortex and hippocampus and less consistently in other regions. We also conclude that physical activity is associated with greater gray matter volume in the same regions that are associated with cardiorespiratory fitness including the prefrontal cortex and hippocampus. Some heterogeneity in the literature may be explained by effect moderation by age, stress, or other factors. Finally, we report promising results from randomized exercise interventions that suggest that the volume of the hippocampus and prefrontal cortex remain pliable and responsive to moderate intensity exercise for 6 months-1 year. Physical activity appears to be a propitious method for influencing gray matter volume in late adulthood, but additional well-controlled studies are necessary to inform public policies about the potential protective or therapeutic effects of exercise on brain volume.

  3. Physical activity, fitness, and gray matter volume.

    Science.gov (United States)

    Erickson, Kirk I; Leckie, Regina L; Weinstein, Andrea M

    2014-09-01

    In this review, we explore the association among physical activity, cardiorespiratory fitness, and exercise on gray matter volume in older adults. We conclude that higher cardiorespiratory fitness levels are routinely associated with greater gray matter volume in the prefrontal cortex and hippocampus and less consistently in other regions. We also conclude that physical activity is associated with greater gray matter volume in the same regions that are associated with cardiorespiratory fitness including the prefrontal cortex and hippocampus. Some heterogeneity in the literature may be explained by effect moderation by age, stress, or other factors. Finally, we report promising results from randomized exercise interventions that suggest that the volume of the hippocampus and prefrontal cortex remain pliable and responsive to moderate intensity exercise for 6 months-1 year. Physical activity appears to be a propitious method for influencing gray matter volume in late adulthood, but additional well-controlled studies are necessary to inform public policies about the potential protective or therapeutic effects of exercise on brain volume. PMID:24952993

  4. Skeletal muscle

    Science.gov (United States)

    There are approximately 650-850 muscles in the human body these include skeletal (striated), smooth and cardiac muscle. The approximation is based on what some anatomists consider separate muscle or muscle systems. Muscles are classified based on their anatomy (striated vs. smooth) and if they are v...

  5. Aging, Tolerance to High Altitude, and Cardiorespiratory Response to Hypoxia.

    Science.gov (United States)

    Richalet, Jean-Paul; Lhuissier, François J

    2015-06-01

    Richalet, Jean-Paul, and François J. Lhuissier. Aging, tolerance to high altitude, and cardiorespiratory response to hypoxia. High Alt Med Biol. 16:117-124, 2015.--It is generally accepted that aging is rather protective, at least at moderate altitude. Some anecdotal reports even mention successful ascent of peaks over 8000 m and even Everest by elderly people. However, very few studies have explored the influence of aging on tolerance to high altitude and prevalence of acute high altitude related diseases, taking into account all confounding factors such as speed of ascent, altitude reached, sex, training status, and chemo-responsiveness. Changes in physiological responses to hypoxia with aging were assessed through a cross-sectional 20-year study including 4675 subjects (2789 men, 1886 women; 14-85 yrs old) and a longitudinal study including 30 subjects explored at a mean 10.4-year interval. In men, ventilatory response to hypoxia increased, while desaturation was less pronounced with aging. Cardiac response to hypoxia was blunted with aging in both genders. Similar results were found in the longitudinal study, with a decrease in cardiac and an increase in ventilatory response to hypoxia with aging. These adaptive responses were less pronounced or absent in post-menopausal untrained women. In conclusion, in normal healthy and active subjects, aging has no deleterious effect on cardiac and ventilatory responses to hypoxia, at least up to the eighth decade. Aging is not a contraindication for high altitude, as far as no pathological condition interferes and physical fitness is compatible with the intensity of the expected physical demand of one's individual. Physiological evaluation through hypoxic exercise testing before going to high altitude is helpful to detect risk factors of severe high altitude-related diseases. PMID:25946570

  6. Health-related fitness profiles in adolescents with complex congenital heart disease

    DEFF Research Database (Denmark)

    Klausen, Susanne Hwiid; Wetterslev, Jørn; Søndergaard, Lars;

    2015-01-01

    PURPOSE: This study investigates whether subgroups of different health-related fitness (HrF) profiles exist among girls and boys with complex congenital heart disease (ConHD) and how these are associated with lifestyle behaviors. METHODS: We measured the cardiorespiratory fitness, muscle strength...... in the Robust clusters reported leading a physically active lifestyle and participants in the Less robust cluster reported leading a sedentary lifestyle. Diagnoses were evenly distributed between clusters. CONCLUSIONS: The cluster analysis attributed some of the variability in cardiorespiratory fitness among...

  7. Inflammatory Mechanisms Associated with Skeletal Muscle Sequelae after Stroke: Role of Physical Exercise.

    Science.gov (United States)

    Coelho Junior, Hélio José; Gambassi, Bruno Bavaresco; Diniz, Tiego Aparecido; Fernandes, Isabela Maia da Cruz; Caperuto, Érico Chagas; Uchida, Marco Carlos; Lira, Fabio Santos; Rodrigues, Bruno

    2016-01-01

    Inflammatory markers are increased systematically and locally (e.g., skeletal muscle) in stroke patients. Besides being associated with cardiovascular risk factors, proinflammatory cytokines seem to play a key role in muscle atrophy by regulating the pathways involved in this condition. As such, they may cause severe decrease in muscle strength and power, as well as impairment in cardiorespiratory fitness. On the other hand, physical exercise (PE) has been widely suggested as a powerful tool for treating stroke patients, since PE is able to regenerate, even if partially, physical and cognitive functions. However, the mechanisms underlying the beneficial effects of physical exercise in poststroke patients remain poorly understood. Thus, in this study we analyze the candidate mechanisms associated with muscle atrophy in stroke patients, as well as the modulatory effect of inflammation in this condition. Later, we suggest the two strongest anti-inflammatory candidate mechanisms, myokines and the cholinergic anti-inflammatory pathway, which may be activated by physical exercise and may contribute to a decrease in proinflammatory markers of poststroke patients. PMID:27647951

  8. Assessing cardiorespiratory capacity in older adults with major depression and Alzheimer disease

    Directory of Open Access Journals (Sweden)

    Marcos Felipe Zanco

    2016-03-01

    Full Text Available ABSTRACT Objective To assess cardiorespiratory capacity through subjective and objective tests in older adults diagnosed with major depression (MDD, Alzheimer disease (AD and healthy older adults. Methods Fifty seven subjects (72 ± 7.9 years were divided into three groups: MDD (n = 20, AD (n = 17 and Healthy (n = 20. The subjects answered Hamilton Scale (HAM-D, Mini-Mental State Examination (MMSE, Veterans Specific Activity Questionnaire (VSAQ and 2-minute Step test. Results MDD and AD showed lower scores than healthy group for Nomogram VSAQ (p < 0.001 and 2-minute Step (p = 0.009; p = 0.008, respectively. Adjusted for age and educational level, no differences among groups were observed for Step (MDD, p = 0.097; AD, p = 0.102. AD group did not present differences to healthy group for Step, when adjusting for MMSE (p = 0.261. Conclusions Despite the lower cardiorespiratory fitness of elderly patients with DM and DA have been found in both evaluations, the results should be viewed with caution, since the tests showed low correlation and different risk classifications of functional loss. In addition, age, level educational and cognitive performance are variables that can influence the performance objective evaluation.

  9. Low Physical Fitness Levels in Older Adults with ID: Results of the HA-ID Study

    Science.gov (United States)

    Hilgenkamp, Thessa I. M.; van Wijck, Ruud; Evenhuis, Heleen M.

    2012-01-01

    Physical fitness is as important to aging adults with ID as in the general population, but to date, the physical fitness levels of this group are unknown. Comfortable walking speed, muscle strength (grip strength), muscle endurance (30 s Chair stand) and cardiorespiratory endurance (10 m incremental shuttle walking test) were tested in a sample of…

  10. Cardiorespiratory responses and prediction of peak oxygen uptake during the shuttle walking test in healthy sedentary adult men.

    Directory of Open Access Journals (Sweden)

    Camila D C Neves

    Full Text Available BACKGROUND: The application of the Shuttle Walking Test (SWT to assess cardiorespiratory fitness and the intensity of this test in healthy participants has rarely been studied. This study aimed to assess and correlate the cardiorespiratory responses of the SWT with the cardiopulmonary exercise testing (CEPT and to develop a regression equation for the prediction of peak oxygen uptake (VO2 peak in healthy sedentary adult men. METHODS: In the first stage of this study, 12 participants underwent the SWT and the CEPT on a treadmill. In the second stage, 53 participants underwent the SWT twice. In both phases, the VO2 peak, respiratory exchange ratio (R, and heart rate (HR were evaluated. RESULTS: Similar results in VO2 peak (P>0.05, R peak (P>0.05 and predicted maximum HR (P>0.05 were obtained between the SWT and CEPT. Both tests showed strong and significant correlations of VO2 peak (r = 0.704, P = 0.01 and R peak (r = 0.737, P0.05 was found. CONCLUSIONS: The SWT produced maximal cardiorespiratory responses comparable to the CEPT, and the developed equation showed viability for the prediction of VO2 peak in healthy sedentary men.

  11. Cardiorespiratory response to cyanide of arterial chemoreceptors in fetal lambs

    Energy Technology Data Exchange (ETDEWEB)

    Itskovitz, J.; Rudolph, A.M.

    1987-05-01

    Cardiorespiratory response to the stimulation of the carotid and aortic receptors by sodium cyanide was examined in fetal lambs in utero at 0.8 (120 days) gestation. Injections of 50-400 ..mu..g cyanide into the inferior vena cava or the carotid artery of intact fetuses elicited bradycardia and respiratory responses that varied from a single gasp to rhythmic respiratory movements but no significant change in arterial blood pressure. Carotid sinus denervation eliminated the cardiorespiratory response to intracarotid injection of cyanide and sinoaortic denervation abolished the response to inferior vena caval injection. It is concluded that in fetal lamb in utero the aortic and carotid bodies are active, and hypoxic stimulation of these chemoreceptors results in cardiorespiratory response characterized by slowing of fetal heart rate, respiratory effort, and no consistent change in arterial blood pressure.

  12. Cardiorespiratory disorders of infants of diabetic mothers

    Directory of Open Access Journals (Sweden)

    Hrabovski Ivan

    2015-01-01

    Full Text Available Introduction. One of the characteristics of modern era is the explosion of diabetes in the world. Today more than 400,000,000 people suffer from diabetes in the entire world. During the last decade the number of women with the disorder of glucose homeostasis is six to seven times greater than in the previous period. Therefore, the re-evaluation of the impact of glucose intolerance on the course and outcome of pregnancy is very current. Objective. The aim of the study was to evaluate the data on the influence of mothers’ glucose homeostasis disturbances on the occurrence of cardiorespiratory disorders in newborns, as well as their influence on the perinatal outcome. Methods. Prospective examination included 102 newborns in total - 31 infants of mothers with glucose homeostasis disorder (Group I and 71 infants of healthy mothers (Group II. Average age, body height, body weight, body mass index, parity and illness duration of the pregnant women had been determined, as well as the delivery method. Every newborn was provided with physical examination, Apgar score was calculated, body weight and body length were measured. Also, electrocardiography and brain ultrasound, as well as the basic hematology biochemical and microbiological analysis, were performed within the examinations of the infants. Results. The average weight and obesity incidence with diabetic women was higher than in the control group and their infants were heavier and with lower gestational age. Heart failures were diagnosed in five (16.1% infants of diabetic mothers and in one (1.4% infant of a healthy woman (p<0.01. Respiratory disorders were diagnosed in 48.4% infants of diabetic mothers and in 12.6% of healthy mothers (p<0.01. Forty-two percent of infants of diabetic mothers and 19.7% infants of healthy mothers needed additional oxygen. Conclusion. Congenital anomalies of the cardiovascular system and respiratory disorders in the infants of diabetic mothers were six to eight

  13. The Pilates method and cardiorespiratory adaptation to training.

    Science.gov (United States)

    Tinoco-Fernández, Maria; Jiménez-Martín, Miguel; Sánchez-Caravaca, M Angeles; Fernández-Pérez, Antonio M; Ramírez-Rodrigo, Jesús; Villaverde-Gutiérrez, Carmen

    2016-01-01

    Although all authors report beneficial health changes following training based on the Pilates method, no explicit analysis has been performed of its cardiorespiratory effects. The objective of this study was to evaluate possible changes in cardiorespiratory parameters with the Pilates method. A total of 45 university students aged 18-35 years (77.8% female and 22.2% male), who did not routinely practice physical exercise or sports, volunteered for the study and signed informed consent. The Pilates training was conducted over 10 weeks, with three 1-hour sessions per week. Physiological cardiorespiratory responses were assessed using a MasterScreen CPX apparatus. After the 10-week training, statistically significant improvements were observed in mean heart rate (135.4-124.2 beats/min), respiratory exchange ratio (1.1-0.9) and oxygen equivalent (30.7-27.6) values, among other spirometric parameters, in submaximal aerobic testing. These findings indicate that practice of the Pilates method has a positive influence on cardiorespiratory parameters in healthy adults who do not routinely practice physical exercise activities. PMID:27357919

  14. Cardiorespiratory Information Dynamics during Mental Arithmetic and Sustained Attention.

    Directory of Open Access Journals (Sweden)

    Devy Widjaja

    Full Text Available An analysis of cardiorespiratory dynamics during mental arithmetic, which induces stress, and sustained attention was conducted using information theory. The information storage and internal information of heart rate variability (HRV were determined respectively as the self-entropy of the tachogram, and the self-entropy of the tachogram conditioned to the knowledge of respiration. The information transfer and cross information from respiration to HRV were assessed as the transfer and cross-entropy, both measures of cardiorespiratory coupling. These information-theoretic measures identified significant nonlinearities in the cardiorespiratory time series. Additionally, it was shown that, although mental stress is related to a reduction in vagal activity, no difference in cardiorespiratory coupling was found when several mental states (rest, mental stress, sustained attention are compared. However, the self-entropy of HRV conditioned to respiration was very informative to study the predictability of RR interval series during mental tasks, and showed higher predictability during mental arithmetic compared to sustained attention or rest.

  15. Fitness, fatness, and academic performance in seventh-grade elementary school students

    OpenAIRE

    Sardinha, Luís B; Marques, Adilson; Martins, Sandra; Palmeira, António; Minderico, Cláudia

    2014-01-01

    Background In addition to the benefits on physical and mental health, cardiorespiratory fitness has shown to have positive effects on cognition. This study aimed to investigate the relationship between cardiorespiratory fitness and body weight status on academic performance among seventh-grade students. Methods Participants included 1531 grade 7 students (787 male, 744 female), ranging in age from 12 to 14 years (M age = 12.3 ± 0.60), from 3 different cohorts. Academic performance was measure...

  16. Beyond vascularization: aerobic fitness is associated with N-acetylaspartate and working memory

    OpenAIRE

    Erickson, Kirk I.; Weinstein, Andrea M.; Sutton, Bradley P.; Prakash, Ruchika Shaurya; Voss, Michelle W.; Chaddock, Laura; Szabo, Amanda N.; Mailey, Emily L; White, Siobhan M.; Thomas R Wojcicki; McAuley, Edward; Arthur F Kramer

    2012-01-01

    Aerobic exercise is a promising form of prevention for cognitive decline; however, little is known about the molecular mechanisms by which exercise and fitness impacts the human brain. Several studies have postulated that increased regional brain volume and function are associated with aerobic fitness because of increased vascularization rather than increased neural tissue per se. We tested this position by examining the relationship between cardiorespiratory fitness and N-acetylaspartate (NA...

  17. Differences Emerge in Visceral Adipose Tissue Accumulation After Selection for Innate Cardiovascular Fitness

    OpenAIRE

    Brock, David W.; Irving, Brian A.; Gower, Barbara; Hunter, Gary R.

    2010-01-01

    Cardiorespiratory fitness (CRF) has been reported to be inversely associated with visceral adipose tissue (VAT) accumulation, independent of body weight. However, the confounding effect of physical activity on the association between CRF and VAT remains inadequately addressed. Based on VO2max, 143 sedentary, overweight women were dichotomized into high-fit (HF) and low-fit (LF) groups. Body composition and VAT were measured using DEXA and CT, respectively, and activity-related energy expendit...

  18. Effect of low-impact aerobic dance on the functional fitness of elderly women.

    Science.gov (United States)

    Hopkins, D R; Murrah, B; Hoeger, W W; Rhodes, R C

    1990-04-01

    To determine the effect of low-impact aerobic dance on sedentary elderly women (N = 53), functional fitness was measured by items from the proposed American Alliance of Health, Physical Education, Recreation, and Dance (AAHPERD) fitness test for older adults. After 12-weeks of low-impact aerobic dance, the group improved significantly on all functional fitness components except motor control/coordination, including cardiorespiratory endurance, strength/endurance, body agility, flexibility, body fat, and balance.

  19. Climate Change and the New Normal for Cardiorespiratory Disease

    Directory of Open Access Journals (Sweden)

    Tim K Takaro

    2015-01-01

    Full Text Available Climate change is already affecting the cardiorespiratory health of populations around the world, and these impacts are expected to increase. The present overview serves as a primer for respirologists who are concerned about how these profound environmental changes may affect their patients. The authors consider recent peer-reviewed literature with a focus on climate interactions with air pollution. They do not discuss in detail cardiorespiratory health effects for which the potential link to climate change is poorly understood. For example, pneumonia and influenza, which affect >500 million people per year, are not addressed, although clear seasonal variation suggests climate-related effects. Additionally, large global health impacts in low-resource countries, including migration precipitated by environmental change, are omitted. The major cardiorespiratory health impacts addressed are due to heat, air pollution and wildfires, shifts in allergens and infectious diseases along with respiratory impacts from flooding. Personal and societal choices about carbon use and fossil energy infrastructure should be informed by their impacts on health, and respirologists can play an important role in this discussion.

  20. Cardiorespiratory compromise under conscious sedation during upper gastrointestinal endoscopy

    International Nuclear Information System (INIS)

    To compare the cardiorespiratory effects of benzodiazepine and midazolam used for sedation in patients undergoing upper gastrointestinal endoscopy with cardiorespiratory changes in the non-sedated patients. A total of 252 adult patients without previous cardiorespiratory co-morbidity, undergoing upper gastrointestinal endoscopy were recruited. They were randomly allocated in to group I (placebo with saline administration), group II (diazepam administered) and group III (midazolam administered). The pulse rate, blood pressure, ECG and peripheral oxygen saturation (SpO/sub 2/ ) was noted at baseline, after pre-medication, during endoscopy and post endoscopy. Statistical analysis was done by paired t-test, Chi-square test and ANOVA as applicable. There was no difference in baseline record of the three groups. Significant fall in SpO/sub 2/ was noted in all the groups, more marked in the sedated one during endoscopy. Tachycardia developed in all the three groups and settled within 5 minutes of endoscopy. Blood pressure remained more stable in the sedated group. ECG changes included atrial and ventricular premature contraction in all the three groups. (author)

  1. Six months of dance intervention enhances postural, sensorimotor, and cognitive performance in elderly without affecting cardio-respiratory functions

    Directory of Open Access Journals (Sweden)

    Jan-ChristophKattenstroth

    2013-02-01

    Full Text Available During aging, sensorimotor, cognitive and physical performance decline, but can improve by training and exercise indicating that age-related changes are treatable. Dancing is increasingly used as an intervention because it combines many diverse features making it a promising neuroplasticity-inducing tool. We here investigated the effects of a 6-months dance class (1 h/week on a group of healthy elderly individuals compared to a matched control group. We performed a broad assessment covering cognition, intelligence, attention, reaction time, motor, tactile, and postural performance, as well as subjective well-being and cardio-respiratory performance. After 6 months, in the control group no changes, or further degradation of performance was found. In the dance group, beneficial effects were found for dance-related parameters such as posture and reaction times, but also for cognitive, tactile, motor performance, and subjective well-being. These effects developed without alterations in the cardio-respiratory performance. Correlation of baseline performance with the improvement following intervention revealed that those individuals, who benefitted most from the intervention, were those who showed the lowest performance prior to the intervention. Our findings corroborate previous observations that dancing evokes widespread positive effects. The pre-post design used in the present study implies that the efficacy of dance is most likely not based on a selection bias of particularly gifted individuals. The lack of changes of cardio-respiratory fitness indicates that even moderate levels of physical activity can in combination with rich sensorimotor, cognitive, social, and emotional challenges act to ameliorate a wide spectrum of age-related decline.

  2. Six months of dance intervention enhances postural, sensorimotor, and cognitive performance in elderly without affecting cardio-respiratory functions.

    Science.gov (United States)

    Kattenstroth, Jan-Christoph; Kalisch, Tobias; Holt, Stephan; Tegenthoff, Martin; Dinse, Hubert R

    2013-01-01

    During aging, sensorimotor, cognitive and physical performance decline, but can improve by training and exercise indicating that age-related changes are treatable. Dancing is increasingly used as an intervention because it combines many diverse features making it a promising neuroplasticity-inducing tool. We here investigated the effects of a 6-month dance class (1 h/week) on a group of healthy elderly individuals compared to a matched control group (CG). We performed a broad assessment covering cognition, intelligence, attention, reaction time, motor, tactile, and postural performance, as well as subjective well-being and cardio-respiratory performance. After 6 months, in the CG no changes, or further degradation of performance was found. In the dance group, beneficial effects were found for dance-related parameters such as posture and reaction times, but also for cognitive, tactile, motor performance, and subjective well-being. These effects developed without alterations in the cardio-respiratory performance. Correlation of baseline performance with the improvement following intervention revealed that those individuals, who benefitted most from the intervention, were those who showed the lowest performance prior to the intervention. Our findings corroborate previous observations that dancing evokes widespread positive effects. The pre-post design used in the present study implies that the efficacy of dance is most likely not based on a selection bias of particularly gifted individuals. The lack of changes of cardio-respiratory fitness indicates that even moderate levels of physical activity can in combination with rich sensorimotor, cognitive, social, and emotional challenges act to ameliorate a wide spectrum of age-related decline.

  3. Water-Based Exercise Improves Health-Related Aspects of Fitness in Older Women.

    Science.gov (United States)

    Takeshima, Nobuo; Rogers, Michael E.; Watanabe, Eiji; Brechue, William F.; Okada, Akiyoshi; Yamada, Tadaki; Islam, Mohammod M.; Hayano, Jyunichirou

    2002-01-01

    Examined the physiological responses of elderly Japanese women to a well-rounded exercise program performed in water. Results indicated that the 12-week program elicited significant improvements in intervention group women's cardiorespiratory fitness, muscular strength, agility, flexibility, body fat, and total cholesterol. Water-based exercise…

  4. Fitness club

    CERN Multimedia

    Fitness club

    2011-01-01

    General fitness Classes Enrolments are open for general fitness classes at CERN taking place on Monday, Wednesday, and Friday lunchtimes in the Pump Hall (building 216). There are shower facilities for both men and women. It is possible to pay for 1, 2 or 3 classes per week for a minimum of 1 month and up to 6 months. Check out our rates and enrol at: http://cern.ch/club-fitness Hope to see you among us! CERN Fitness Club fitness.club@cern.ch  

  5. Fitness, but not physical activity, is related to functional integrity of brain networks associated with aging.

    Science.gov (United States)

    Voss, Michelle W; Weng, Timothy B; Burzynska, Agnieszka Z; Wong, Chelsea N; Cooke, Gillian E; Clark, Rachel; Fanning, Jason; Awick, Elizabeth; Gothe, Neha P; Olson, Erin A; McAuley, Edward; Kramer, Arthur F

    2016-05-01

    Greater physical activity and cardiorespiratory fitness are associated with reduced age-related cognitive decline and lower risk for dementia. However, significant gaps remain in the understanding of how physical activity and fitness protect the brain from adverse effects of brain aging. The primary goal of the current study was to empirically evaluate the independent relationships between physical activity and fitness with functional brain health among healthy older adults, as measured by the functional connectivity of cognitively and clinically relevant resting state networks. To build context for fitness and physical activity associations in older adults, we first demonstrate that young adults have greater within-network functional connectivity across a broad range of cortical association networks. Based on these results and previous research, we predicted that individual differences in fitness and physical activity would be most strongly associated with functional integrity of the networks most sensitive to aging. Consistent with this prediction, and extending on previous research, we showed that cardiorespiratory fitness has a positive relationship with functional connectivity of several cortical networks associated with age-related decline, and effects were strongest in the default mode network (DMN). Furthermore, our results suggest that the positive association of fitness with brain function can occur independent of habitual physical activity. Overall, our findings provide further support that cardiorespiratory fitness is an important factor in moderating the adverse effects of aging on cognitively and clinically relevant functional brain networks.

  6. Effect of Physical Exercise on the Cardiorespiratory Response in Overweight Adolescents

    Directory of Open Access Journals (Sweden)

    Diego A S Silva

    2012-03-01

    Full Text Available Purpose: To evaluate the effects of an aerobic physical exercise program on the metabolic and cardiorespiratory response in overweight adolescents.Material and Method: This is a randomized study evaluating overweight adolescents divided into intervention and control groups before and after an aerobic exercise program. Pre- and post-intervention aerobic fitness was evaluated by a submaximal incremental test on a cycle ergometer. The training program lasted 12 weeks, when the intervention group exercised three times per week on a cycle ergometer at individual training intensities corresponding to lactate threshold (LT and onset of blood lactate accumulation (OBLA. The individual workload was increased by 10% at 2-week intervals.Results: After intervention, an increase in workload levels corresponding to LT (33.3% and OBLA (14.2% was observed in the intervention group. In addition, the intervention group reached LT training intensity at a heart rate higher than that observed before intervention and that of controls (p<0.05. Discussion: The program resulted in positive changes in aerobic fitness and heart rate, improving exercise tolerance. Turk Jem 2012; 16: 14-8

  7. The effect of neoadjuvant chemoradiotherapy on whole-body physical fitness and skeletal muscle mitochondrial oxidative phosphorylation in vivo in locally advanced rectal cancer patients--an observational pilot study.

    Directory of Open Access Journals (Sweden)

    Malcolm A West

    Full Text Available BACKGROUND: In the United Kingdom, patients with locally advanced rectal cancer routinely receive neoadjuvant chemoradiotherapy. However, the effects of this on physical fitness are unclear. This pilot study is aimed to investigate the effect of neoadjuvant chemoradiotherapy on objectively measured in vivo muscle mitochondrial function and whole-body physical fitness. METHODS: We prospectively studied 12 patients with rectal cancer who completed standardized neoadjuvant chemoradiotherapy, recruited from a large tertiary cancer centre, between October 2012 and July 2013. All patients underwent a cardiopulmonary exercise test and a phosphorus magnetic resonance spectroscopy quadriceps muscle exercise-recovery study before and after neoadjuvant chemoradiotherapy. Data were analysed and reported blind to patient identity and clinical course. Primary variables of interest were the two physical fitness measures; oxygen uptake at estimated anaerobic threshold and oxygen uptake at Peak exercise (ml.kg-1.min-1, and the post-exercise phosphocreatine recovery rate constant (min-1, a measure of muscle mitochondrial capacity in vivo. RESULTS: Median age was 67 years (IQR 64-75. Differences (95%CI in all three primary variables were significantly negative post-NACRT: Oxygen uptake at estimated anaerobic threshold -2.4 ml.kg-1.min-1 (-3.8, -0.9, p = 0.004; Oxygen uptake at Peak -4.0 ml.kg-1.min-1 (-6.8, -1.1, p = 0.011; and post-exercise phosphocreatine recovery rate constant -0.34 min-1 (-0.51, -0.17, p<0.001. CONCLUSION: The significant decrease in both whole-body physical fitness and in vivo muscle mitochondrial function raises the possibility that muscle mitochondrial mechanisms, no doubt multifactorial, may be important in deterioration of physical fitness following neoadjuvant chemoradiotherapy. This may have implications for targeted interventions to improve physical fitness pre-surgery. TRIAL REGISTRATION: Clinicaltrials.gov registration NCT01859442.

  8. Effect of 11 months of yoga training on cardiorespiratory responses during the actual practice of Surya Namaskar

    Directory of Open Access Journals (Sweden)

    Biswajit Sinha

    2014-01-01

    Full Text Available Background: Surya Namaskar (SN, a popular traditional Indian yogic practice, includes practicing 12 physical postures with alternate forward and backward bending movement of the body along with deep breathing maneuvers. The practice of SN has become popular among yoga practitioners and other fitness conscious people. The long-term effect of practicing SN and other yogic practices on cardiorespiratory responses during SN are lacking. Aim: The present study was conducted to study the effect of yogic training on various cardiorespiratory responses during the SN practice in yoga trainees after a time interval of 3, 6, and 11 months. Materials and Methods: The present study was conducted on 9 healthy male Army soldiers who underwent training in various yoga postures including SN, meditation, and pranayama for 1 h daily for 11 months. First, second, and third phase of the study was conducted in the laboratory after completion of 3, 6, and 11 months of the yoga training. The participants performed SN along with other yogic practices in the laboratory as per their daily practice schedule. The cardiorespiratory responses of the volunteers were recorded during actual practice of SN. Statistical Analysis: One-way repeated measure ANOVA followed by Tukey HSD. Results: Oxygen consumption and heart rate during actual practice of SN was 0.794 ± 0.252, 0.738 ± 0.229, and 0.560 ± 0.165 L/min and 92.1 ± 11.6, 97.9 ± 7.3 and 87.4 ± 9.2 beats/min respectively at 1 st , 2 nd , and 3 rd phase of yoga training. Minute ventilation and tidal volume also reduced from 19.9 ± 4.65 to 17.8 ± 4.41 L/min and 1.091 ± 0.021 to 0.952 L/breath from 1 st phase to 3 rd phase of yoga training. However, respiratory parameters like breathing rate (f R did not show any reduction across the three phases. Conclusion: The results of the present study indicated that yogic training caused conditioning of cardiorespiratory parameters except f R, which did not reduce across three

  9. Fitness Club

    CERN Multimedia

    Fitness Club

    2011-01-01

    The CERN Fitness Club is organising Zumba Classes on the first Wednesday of each month, starting 7 September (19.00 – 20.00). What is Zumba®? It’s an exhilarating, effective, easy-to-follow, Latin-inspired, calorie-burning dance fitness-party™ that’s moving millions of people toward joy and health. Above all it’s great fun and an excellent work out. Price: 22 CHF/person Sign-up via the following form: https://espace.cern.ch/club-fitness/Lists/Zumba%20Subscription/NewForm.aspx For more info: fitness.club@cern.ch

  10. Assessment of cardiorespiratory fitness using submaximal protocol in older adults with mood disorder and Parkinson's disease

    Directory of Open Access Journals (Sweden)

    Natacha Alves de Oliveira

    2013-01-01

    Full Text Available BACKGROUND: Evidence has shown benefits for mental health through aerobic training oriented in percentage of VO2max, indicating the importance of this variable for clinical practice. OBJECTIVE: To validate a method for estimating VO2max using a submaximal protocol in elderly patients with clinically diagnosis as major depressive disorder (MDD and Parkinson's disease (PD. METHODS: The sample comprised 18 patients (64.22 ± 9.92 years with MDD (n = 7 and with PD (n = 11. Three evaluations were performed: I disease staging, II direct measurement of VO2max and III submaximal exercise test. Linear regression was performed to verify the accuracy of estimation in VO2max established in ergospirometry and the predicted VO2max from the submaximal test measurement. We also analyzed the correlation between the Bland-Altman procedures. RESULTS: The regression analysis showed that VO2max values estimated by submaximal protocol associated with the VO2max measured, both in absolute values (R² = 0.65; SEE = 0.26; p < 0.001 and the relative (R² = 0.56; SEE = 3.70; p < 0.001. The Bland-Altman plots for analysis of agreement of showed a good correlation between the two measures. DISCUSSION: The VO2max predicted by submaximal protocol demonstrated satisfactory criterion validity and simple execution compared to ergospirometry.

  11. Cardiorespiratory fitness of asthmatic children and validation of predicted aerobic capacity

    DEFF Research Database (Denmark)

    Lochte, Lene; Angermann, Marie; Larsson, Benny

    2009-01-01

    ). Physical activity level and subjective health showed no differences between groups, or level and categories, respectively. CONCLUSION: The asthmatic participants presented with lower aerobic capacity than controls in both PAC and MAC; therefore, results confirmed the validity of the PAC method. Data......INTRODUCTION: Predicted aerobic capacity (PAC) was estimated by submaximal exercise test and compared with monitored aerobic capacity (MAC) measured by laboratory conditions [maximal oxygen uptake (VO(2peak))] in 18 children and adolescents, 10 asthmatics and 8 matched controls. Objectives...... for statistical evaluation; the method of Bland and Altman estimated the agreement between PAC and MAC; P mean difference between PAC and MAC at follow-up was -1.0 mLO(2)/min...

  12. Does aerobic exercise improve or impair cardiorespiratory fitness and health among cleaners?

    DEFF Research Database (Denmark)

    Korshøj Larsen, Mette; Lidegaard, Mark; Skotte, Jørgen H;

    2015-01-01

    OBJECTIVE: It is unknown if aerobic exercise overloads or improves the cardiovascular system among workers with high occupational physical activity. This was investigated in a worksite randomized controlled trial (RCT) of aerobic exercise among cleaners. METHODS: We randomized 116 cleaners between...

  13. Cardiorespiratory fitness, cardiovascular workload and risk factors among cleaners; a cluster randomized worksite intervention

    DEFF Research Database (Denmark)

    Korshøj, Mette; Krustrup, Peter; Jørgensen, Marie Birk;

    2012-01-01

    . The clusters will be balanced on the following criteria: Geographical work location, gender, age and seniority. Cleaners are randomized to either I) a reference group, receiving lectures concerning healthy living, or II) an intervention group, performing worksite aerobic exercise. Data collection...

  14. The Impact of Achievement Goals on Cardiorespiratory Fitness: Does Self-Efficacy Make a Difference?

    Science.gov (United States)

    Gao, Zan; Xiang, Ping; Lochbaum, Marc; Guan, Jianmin

    2013-01-01

    Purpose: The relationships among students' self-efficacy, 2 × 2 achievement goals (mastery-approach [MAp], mastery-avoidance [MAv], performance-approach [PAp], and performance-avoidance goals), and achievement performance remain largely unanswered. We tested a model of the mediating role of self-efficacy on the relationship between 2 × 2…

  15. Age-Related Decline in Cardiorespiratory Fitness among Career Firefighters: Modification by Physical Activity and Adiposity

    Directory of Open Access Journals (Sweden)

    Dorothee M. Baur

    2012-01-01

    We found as expected that CRF declines with advancing age; however, the decline is greatly attenuated among leaner firefighters who report more physical activity. Furthermore, in a linear regression model including age, BMI, and variables describing physical activity behaviors, we could predict CRF (R2=0.6286. The total weekly duration of aerobic exercise as well as the duration of weight lifting sessions both had significant impacts on age-related decline. We conclude that firefighters are more likely to maintain the high levels of CRF needed to safely perform their duties if they engage in frequent exercise and maintain healthy weights.

  16. Noncontact monitoring of cardiorespiratory activity by electromagnetic coupling.

    Science.gov (United States)

    Teichmann, Daniel; Foussier, Jérôme; Jia, Jing; Leonhardt, Steffen; Walter, Marian

    2013-08-01

    In this paper, the method of noncontact monitoring of cardiorespiratory activity by electromagnetic coupling with human tissue is investigated. Two measurement modalities were joined: an inductive coupling sensor based on magnetic eddy current induction and a capacitive coupling sensor based on displacement current induction. The system's sensitivity to electric tissue properties and its dependence on motion are analyzed theoretically as well as experimentally for the inductive and capacitive coupling path. The potential of both coupling methods to assess respiration and pulse without contact and a minimum of thoracic wall motion was verified by laboratory experiments. The demonstrator was embedded in a chair to enable recording from the back part of the thorax.

  17. Fitness cost

    DEFF Research Database (Denmark)

    Nielsen, Karen L.; Pedersen, Thomas M.; Udekwu, Klas I.;

    2012-01-01

    of each isolate was determined in a growth competition assay with a reference isolate. Significant fitness costs of 215 were determined for the MRSA isolates studied. There was a significant negative correlation between number of antibiotic resistances and relative fitness. Multiple regression analysis...

  18. Fodbold Fitness

    DEFF Research Database (Denmark)

    Bennike, Søren

    Samfundet forandrer sig og ligeså gør danskernes idrætsmønstre. Fodbold Fitness, der er afhandlingens omdrejningspunkt, kan iagttages som en reaktion på disse forandringer. Afhandlingen ser nærmere på Fodbold Fitness og implementeringen af dette, der ingenlunde er nogen let opgave. Bennike bidrager...

  19. A cardiorespiratory classifier of voluntary and involuntary electrodermal activity

    Directory of Open Access Journals (Sweden)

    Sejdic Ervin

    2010-02-01

    Full Text Available Abstract Background Electrodermal reactions (EDRs can be attributed to many origins, including spontaneous fluctuations of electrodermal activity (EDA and stimuli such as deep inspirations, voluntary mental activity and startling events. In fields that use EDA as a measure of psychophysiological state, the fact that EDRs may be elicited from many different stimuli is often ignored. This study attempts to classify observed EDRs as voluntary (i.e., generated from intentional respiratory or mental activity or involuntary (i.e., generated from startling events or spontaneous electrodermal fluctuations. Methods Eight able-bodied participants were subjected to conditions that would cause a change in EDA: music imagery, startling noises, and deep inspirations. A user-centered cardiorespiratory classifier consisting of 1 an EDR detector, 2 a respiratory filter and 3 a cardiorespiratory filter was developed to automatically detect a participant's EDRs and to classify the origin of their stimulation as voluntary or involuntary. Results Detected EDRs were classified with a positive predictive value of 78%, a negative predictive value of 81% and an overall accuracy of 78%. Without the classifier, EDRs could only be correctly attributed as voluntary or involuntary with an accuracy of 50%. Conclusions The proposed classifier may enable investigators to form more accurate interpretations of electrodermal activity as a measure of an individual's psychophysiological state.

  20. Fitness Club

    CERN Document Server

    Fitness Club

    2012-01-01

    Open to All: http://cern.ch/club-fitness  fitness.club@cern.ch Boxing Your supervisor makes your life too tough ! You really need to release the pressure you've been building up ! Come and join the fit-boxers. We train three times a week in Bd 216, classes for beginners and advanced available. Visit our website cern.ch/Boxing General Fitness Escape from your desk with our general fitness classes, to strengthen your heart, muscles and bones, improve you stamina, balance and flexibility, achieve new goals, be more productive and experience a sense of well-being, every Monday, Wednesday and Friday lunchtime, Tuesday mornings before work and Thursday evenings after work – join us for one of our monthly fitness workshops. Nordic Walking Enjoy the great outdoors; Nordic Walking is a great way to get your whole body moving and to significantly improve the condition of your muscles, heart and lungs. It will boost your energy levels no end. Pilates A body-conditioning technique de...

  1. Acute hernial strangulation following Wii Fit exercises.

    Science.gov (United States)

    Khan, O A; Parvaiz, A C; Vassallo, D J

    2013-01-01

    The Wii Fit is one the most popular fitness games on the market. Although this device has been linked to a number of injuries, the vast majority of these have been relatively minor musculo-skeletal complaints. We present a case of a patient who presented with an acute strangulation of a pre-existing asymptomatic paraumbilical hernia after completing a series of aerobic exercises on her Wii Fit. She required laparotomy and small bowel resection for infarcted bowel. Although a number of minor mechanical and orthopaedic injurieshave been reported with the Wii Fit, this represents the first case of a life-threatening complication associated with the use of this device.

  2. Fitness, inclusive fitness, and optimization

    OpenAIRE

    Lehmann L.; Rousset F

    2014-01-01

    Individual-as-maximizing agent analogies result in a simple understanding of the functioning of the biological world. Identifying the conditions under which individuals can be regarded as fitness maximizing agents is thus of considerable interest to biologists. Here, we compare different concepts of fitness maximization, and discuss within a single framework the relationship between Hamilton's (J Theor Biol 7: 1-16, 1964) model of social interactions, Grafen's (J Evol Biol 20: 1243-1254, 2007...

  3. The effect of Sub-maximal exercise-rehabilitation program on cardio-respiratory endurance indexes and oxygen pulse in patients with spastic cerebral palsy

    Directory of Open Access Journals (Sweden)

    M Izadi

    2006-05-01

    Full Text Available Background: Physical or cardio-respiratory fitness are of the best important physiological variables in children with cerebral palsy (CP, but the researches on exercise response of individuals with CP are limited. Our aim was to determine the effect of sub-maximal rehabilitation program (aerobic exercise on maximal oxygen uptake, oxygen pulse and cardio- respiratory physiological variables of children with moderate to severe spastic cerebral palsy diplegia and compare with able-bodied children. Methods: In a controlled clinical trial study, 15 children with diplegia spastic cerebral palsy, were recruited on a voluntarily basis (experimental group and 18 subjects without neurological impairments selected as control group. In CP group, aerobic exercise program performed on the average of exercise intensity (144 beat per minute of heart rate, 3 times a week for 3 months. The time of each exercise session was 20-25 minutes. Dependent variables were measured in before (pretest and after (post test of rehabilitation program through Mac Master Protocol on Tantories cycle ergometer in CP group and compared with the control group. Results: The oxygen pulse (VO2/HR during ergometery protocol was significantly lower in CP group than normal group (P<0.05. No significant statistical difference in maximal oxygen uptake (VO2 max was found between groups. The rehabilitation program leads to little increase of this variable in CP group. After sub-maximal exercise in pretest and post test, the heart rate of patient group was greater than control group, and aerobic exercise leads to significant decrease in heart rate in CP patients(P<0.05. Conclusion: The patients with spastic cerebral palsy, because of high muscle tone, severe spasticity and involuntarily movements have higher energy cost and lower aerobic fitness than normal people. The rehabilitation exercise program can improve physiological function of muscle and cardio-respiratory endurance in these

  4. Cardiorespiratory events in preterm infants: etiology and monitoring technologies.

    Science.gov (United States)

    Di Fiore, J M; Poets, C F; Gauda, E; Martin, R J; MacFarlane, P

    2016-03-01

    Every year, an estimated 15 million infants are born prematurely (premature birth rates ranging from 5 to 18% across 184 countries. Although there are a multitude of reasons for this high rate of preterm birth, once birth occurs, a major challenge of infant care includes the stabilization of respiration and oxygenation. Clinical care of this vulnerable infant population continues to improve, yet there are major areas that have yet to be resolved including the identification of optimal respiratory support modalities and oxygen saturation targets, and reduction of associated short- and long-term morbidities. As intermittent hypoxemia is a consequence of immature respiratory control and resultant apnea superimposed upon an immature lung, improvements in clinical care must include a thorough knowledge of premature lung development and pathophysiology that is unique to premature birth. In Part 1 of a two-part review, we summarize early lung development and diagnostic methods for cardiorespiratory monitoring. PMID:26583939

  5. Identification of coupling direction: Application to cardiorespiratory interaction

    Science.gov (United States)

    Rosenblum, Michael G.; Cimponeriu, Laura; Bezerianos, Anastasios; Patzak, Andreas; Mrowka, Ralf

    2002-04-01

    We consider the problem of experimental detection of directionality of weak coupling between two self-sustained oscillators from bivariate data. We further develop the method introduced by Rosenblum and Pikovsky [Phys. Rev. E 64, 045202 (2001)], suggesting an alternative approach. Next, we consider another framework for identification of directionality, based on the idea of mutual predictability. Our algorithms provide directionality index that shows whether the coupling between the oscillators is unidirectional or bidirectional, and quantifies the asymmetry of bidirectional coupling. We demonstrate the efficiency of three different algorithms in determination of directionality index from short and noisy data. These techniques are then applied to analysis of cardiorespiratory interaction in healthy infants. The results reveal that the direction of coupling between cardiovascular and respiratory systems varies with the age within the first 6 months of life. We find a tendency to change from nearly symmetric bidirectional interaction to nearly unidirectional one (from respiration to the cardiovascular system).

  6. Cardiorespiratory responses during deep water running with and without horizontal displacement at different cadences

    Directory of Open Access Journals (Sweden)

    A.C. Kanitz

    2014-12-01

    Conclusions: The results indicate that the increase in both cadence and displacement results in significant cardiorespiratory responses as a result of deep water running. This finding is important for adapting exercise prescription to the goals of participants.

  7. Fitness club

    CERN Document Server

    Fitness club

    2013-01-01

      Nordic Walking Classes Come join the Nordic walking classes and outings offered by the CERN Fitness Club starting September 2013. Our licensed instructor Christine offers classes for people who’ve never tried Nordic Walking and who would like to learn the technique, and outings for people who have completed the classes and enjoy going out as a group. Course 1: Tuesdays 12:30 - 13:30 24 September, 1 October, 8 October, 15 October Course 2: Tuesdays 12:30 - 13:30 5 November, 12 November, 19 November, 26 November Outings will take place on Thursdays (12:30 to 13:30) from 12 September 2013. We meet at the CERN Club Barracks car park (close to Entrance A) 10 minutes before departure. Prices: 50 CHF for 4 classes, including the 10 CHF Club membership. Payments made directly to instructor. Renting Poles: Poles can be rented from Christine at 5 CHF / hour. Subscription: Please subscribe at: http://cern.ch/club-fitness Looking forward to seeing you among us! Fitness Club FitnessClub@c...

  8. Fitness Basics

    Science.gov (United States)

    ... that gets your heart pumping, such as dancing, running, or swimming laps. How hard you exercise matters, too. You can learn how to measure your workout to see if it is light, medium, or intense. Fitness for all Do you have an illness or ...

  9. Fitness Club

    CERN Multimedia

    Fitness Club

    2012-01-01

    Get in Shape for Summer with the CERN Fitness Club Saturday 23 June 2012 from 14:30 to 16.30 (doors open at 14.00) Germana’s Fitness Workshop. Build strength and stamina, sculpt and tone your body and get your heart pumping with Germana’s workout mixture of Cardio Attack, Power Pump, Power Step, Cardio Combat and Cross-Training. Where: 216 (Pump room – equipped with changing rooms and showers). What to wear: comfortable clothes and indoor sports shoes + bring a drink! How much: 15 chf Sign up here: https://espace.cern.ch/club-fitness/Lists/Test_Subscription/NewForm.aspx? Join the Party and dance yourself into shape at Marco + Marials Zumba Masterclass. Saturday 30 June 2012 from 15:00 to 16:30 Marco + Mariel’s Zumba Masterclass Where: 216 (Pump room – equipped with changing rooms and showers). What to wear: comfortable clothes and indoor sports shoes + bring a drink! How much: 25 chf Sign up here: https://espace.cern.ch/club-fitness/Lists/Zumba%20...

  10. Fitness Club

    CERN Multimedia

    Fitness Club

    2010-01-01

    Nordic Walking Please note that the subscriptions for the general fitness classes from July to December are open: Subscriptions general fitness classes Jul-Dec 2010 Sign-up to the Fitness Club mailing list here Nordic Walking: Sign-up to the Nordic Walking mailing list here Beginners Nordic walking lessons Monday Lunchtimes (rdv 12:20 for 12:30 departure) 13.09/20.09/27.09/04.10 11.10/18.10/08.11/15.11 22.11/29.11/06.12/20.12 Nordic walking lessons Tuesday evenings (rdv 17:50 for 18:00 departure) 07.09/14.09/21.09/28.09 05.10/12.10/19.10/26.10 Intermediate/Advanced Nordic walking outings (follow the nordic walking lessons before signing up for the outings) every Thursday from 16.09 - 16.12, excluding 28.10 and 09.12 Subscriptions and info: fitness.club@cern.ch  

  11. Fitness Club

    CERN Multimedia

    Fitness Club

    2012-01-01

      The CERN Fitness Club is pleased to announce its new early morning class which will be taking place on: Tuesdays from 24th April 07:30 to 08:15 216 (Pump Hall, close to entrance C) – Facilities include changing rooms and showers. The Classes: The early morning classes will focus on workouts which will help you build not only strength and stamina, but will also improve your balance, and coordination. Our qualified instructor Germana will accompany you throughout the workout  to ensure you stay motivated so you achieve the best results. Sign up and discover the best way to start your working day full of energy! How to subscribe? We invite you along to a FREE trial session, if you enjoy the activity, please sign up via our website: https://espace.cern.ch/club-fitness/Activities/SUBSCRIBE.aspx. * * * * * * * * Saturday 28th April Get in shape for the summer at our fitness workshop and zumba dance party: Fitness workshop with Germana 13:00 to 14:30 - 216 (Pump Hall) Price...

  12. Cognitive fitness.

    Science.gov (United States)

    Gilkey, Roderick; Kilts, Clint

    2007-11-01

    Recent neuroscientific research shows that the health of your brain isn't, as experts once thought, just the product of childhood experiences and genetics; it reflects your adult choices and experiences as well. Professors Gilkey and Kilts of Emory University's medical and business schools explain how you can strengthen your brain's anatomy, neural networks, and cognitive abilities, and prevent functions such as memory from deteriorating as you age. The brain's alertness is the result of what the authors call cognitive fitness -a state of optimized ability to reason, remember, learn, plan, and adapt. Certain attitudes, lifestyle choices, and exercises enhance cognitive fitness. Mental workouts are the key. Brain-imaging studies indicate that acquiring expertise in areas as diverse as playing a cello, juggling, speaking a foreign language, and driving a taxicab expands your neural systems and makes them more communicative. In other words, you can alter the physical makeup of your brain by learning new skills. The more cognitively fit you are, the better equipped you are to make decisions, solve problems, and deal with stress and change. Cognitive fitness will help you be more open to new ideas and alternative perspectives. It will give you the capacity to change your behavior and realize your goals. You can delay senescence for years and even enjoy a second career. Drawing from the rapidly expanding body of neuroscience research as well as from well-established research in psychology and other mental health fields, the authors have identified four steps you can take to become cognitively fit: understand how experience makes the brain grow, work hard at play, search for patterns, and seek novelty and innovation. Together these steps capture some of the key opportunities for maintaining an engaged, creative brain. PMID:18159786

  13. A Comparison between Alpine Skiing, Cross-Country Skiing and Indoor Cycling on Cardiorespiratory and Metabolic Response

    Directory of Open Access Journals (Sweden)

    Thomas Stöggl, Christoph Schwarzl, Edith E. Müller, Masaru Nagasaki, Julia Stöggl, Peter Scheiber, Martin Schönfelder, Josef Niebauer

    2016-03-01

    Full Text Available Since physical inactivity especially prevails during winter months, we set out to identify outdoor alternatives to indoor cycling (IC by comparing the metabolic and cardiorespiratory responses during alpine skiing (AS, cross-country skiing (XCS and IC and analyse the effects of sex, age and fitness level in this comparison. Twenty one healthy subjects performed alpine skiing (AS, cross-country skiing (XCS, and IC. Oxygen uptake (VO2, total energy expenditure (EE, heart rate (HR, lactate, blood glucose and rate of perceived exertion (RPE were determined during three 4-min stages of low, moderate and high intensity. During XCS and IC VO2max and EE were higher than during AS. At least 2½ hours of AS are necessary to reach the same EE as during one hour of XCS or IC. HR, VO2, lactate, and RPEarms were highest during XCS, whereas RPEwhole-body was similar and RPElegs lower than during AS and IC, respectively. Weight adjusted VO2 and EE were higher in men than in women while fitness level had no effect. Male, fit and young participants were able to increase their EE and VO2 values more pronounced. Both AS and XCS can be individually tailored to serve as alternatives to IC and may thus help to overcome the winter activity deficit. XCS was found to be the most effective activity for generating a high EE and VO2 while AS was the most demanding activity for the legs.

  14. What Is the Relationship between Outdoor Time and Physical Activity, Sedentary Behaviour, and Physical Fitness in Children? A Systematic Review

    Directory of Open Access Journals (Sweden)

    Casey Gray

    2015-06-01

    Full Text Available The objective of this systematic review was to examine the relationship between outdoor time and: (1 physical activity, (2 cardiorespiratory fitness, (3 musculoskeletal fitness, (4 sedentary behaviour; or (5 motor skill development in children aged 3–12 years. We identified 28 relevant studies that were assessed for quality using the GRADE framework. The systematic review revealed overall positive effects of outdoor time on physical activity, sedentary behaviour, and cardiorespiratory fitness, although causality could not be assumed due to a lack of RCTs. Motor skill development was unrelated to outdoor time; however, this relationship was only examined in a single study of preschool children. No studies were found that examined associations between outdoor time and musculoskeletal fitness.

  15. A Comparison between Alpine Skiing, Cross-Country Skiing and Indoor Cycling on Cardiorespiratory and Metabolic Response.

    Science.gov (United States)

    Stöggl, Thomas; Schwarzl, Christoph; Müller, Edith E; Nagasaki, Masaru; Stöggl, Julia; Scheiber, Peter; Schönfelder, Martin; Niebauer, Josef

    2016-03-01

    Since physical inactivity especially prevails during winter months, we set out to identify outdoor alternatives to indoor cycling (IC) by comparing the metabolic and cardiorespiratory responses during alpine skiing (AS), cross-country skiing (XCS) and IC and analyse the effects of sex, age and fitness level in this comparison. Twenty one healthy subjects performed alpine skiing (AS), cross-country skiing (XCS), and IC. Oxygen uptake (VO2), total energy expenditure (EE), heart rate (HR), lactate, blood glucose and rate of perceived exertion (RPE) were determined during three 4-min stages of low, moderate and high intensity. During XCS and IC VO2max and EE were higher than during AS. At least 2½ hours of AS are necessary to reach the same EE as during one hour of XCS or IC. HR, VO2, lactate, and RPEarms were highest during XCS, whereas RPEwhole-body was similar and RPElegs lower than during AS and IC, respectively. Weight adjusted VO2 and EE were higher in men than in women while fitness level had no effect. Male, fit and young participants were able to increase their EE and VO2 values more pronounced. Both AS and XCS can be individually tailored to serve as alternatives to IC and may thus help to overcome the winter activity deficit. XCS was found to be the most effective activity for generating a high EE and VO2 while AS was the most demanding activity for the legs. Key pointsDuring cross-country skiing and indoor cycling VO2max and energy expenditure were higher than during alpine skiingApproximately 2½ hours of alpine skiing are necessary to reach the same energy expenditure of one hour of cross-country skiing or indoor cycling.Alpine skiing and cross-country skiing can be individually tailored to serve as sports alternatives in winter to activity deficit.By applying different skiing modes as parallel ski steering, carving long radii and short turn skiing, metabolic and cardiorespiratory response can be increased during alpine skiing.Male, fit and young

  16. Fitness Club

    CERN Multimedia

    Fitness Club

    2012-01-01

    Nordic Walking Classes Sessions of four classes of one hour each are held on Tuesdays. RDV barracks parking at Entrance A, 10 minutes before class time. Session 1 =  11.09 / 18.09 / 25.09 / 02.10, 18:15 - 19:15 Session 2 = 25.09 / 02.10 / 09.10 / 16.10, 12:30 - 13:30 Session 3 = 23.10 / 30.10 / 06.11 / 13.11, 12:30 - 13:30 Session 4 = 20.11 / 27.11 / 04.12 / 11.12, 12:30 - 13:30 Prices 40 CHF per session + 10 CHF club membership 5 CHF/hour pole rental Check out our schedule and enroll at http://cern.ch/club-fitness   Hope to see you among us!  fitness.club@cern.ch In spring 2012 there was a long-awaited progress in CERN Fitness club. We have officially opened a Powerlifting @ CERN, and the number of members of the new section has been increasing since then reaching 70+ people in less than 4 months. Powerlifting is a strength sport, which is simple as 1-2-3 and efficient. The "1-2-3" are the three basic lifts (bench press...

  17. Effects of Long-Term Dharma-Chan Meditation on Cardiorespiratory Synchronization and Heart Rate Variability Behavior

    OpenAIRE

    Chang, Chih-Hao; Lo, Pei-Chen

    2013-01-01

    Remarkable changes in cardiorespiratory interactions are frequently experienced by Chan meditation practitioners following years of practice. This study compares the results of our study on cardiorespiratory interactions for novice (control group) and experienced (experimental group) Chan meditation practitioners. The effectual co-action between the cardiac and respiratory systems was evaluated by the degree of cardiorespiratory phase synchronization (CRPS). In addition, an adaptive-frequency...

  18. Adiposity and Age Explain Most of the Association between Physical Activity and Fitness in Physically Active Men

    OpenAIRE

    Serrano-Sánchez, José A.; Safira Delgado-Guerra; Hugo Olmedillas; Amelia Guadalupe-Grau; Rafael Arteaga-Ortiz; Joaquín Sanchis-Moysi; Cecilia Dorado; Calbet, José A. L.

    2010-01-01

    BACKGROUND: To determine if there is an association between physical activity assessed by the short version of the International Physical Activity Questionnaire (IPAQ) and cardiorespiratory and muscular fitness. METHODOLOGY/PRINCIPAL FINDINGS: One hundred and eighty-two young males (age range: 20-55 years) completed the short form of the IPAQ to assess physical activity. Body composition (dual-energy X-Ray absorptiometry), muscular fitness (static and dynamic muscle force and power, vertical ...

  19. Improving health-related fitness in adolescents: the CrossFit Teens™ randomised controlled trial.

    Science.gov (United States)

    Eather, Narelle; Morgan, Philip James; Lubans, David Revalds

    2016-01-01

    The aim of this study was to evaluate the preliminary efficacy and feasibility of the CrossFit Teens™ resistance training programme for improving health-related fitness and resistance training skill competency in adolescents. This assessor-blinded randomised controlled trial was conducted in one secondary school in the Hunter Region, Australia, from July to September 2013. Ninety-six (96) students (age = 15.4 (.5) years, 51.5% female) were randomised into intervention (n = 51) or control (n = 45) conditions for 8-weeks (60 min twice per week). Waist circumference, body mass index (BMI), BMI-Z score (primary outcomes), cardiorespiratory fitness (shuttle run test), muscular fitness (standing jump, push-up, handgrip, curl-up test), flexibility (sit and reach) and resistance training skill competency were measured at baseline and immediate post-intervention. Feasibility measures of recruitment, retention, adherence and satisfaction were assessed. Significant group-by-time intervention effects were found for waist circumference [-3.1 cm, P CrossFit Teens™ is a feasible and efficacious programme for improving health-related fitness in adolescents. PMID:25972203

  20. Fitness club

    CERN Multimedia

    Fitness club

    2013-01-01

    Nordic Walking Classes New session of 4 classes of 1 hour each will be held on Tuesdays in May 2013. Meet at the CERN barracks parking at Entrance A, 10 minutes before class time. Dates and time: 07.05, 14.05, 21.05 and 28.05, fom  12 h 30 to 13 h 30 Prices: 40 CHF per session + 10 CHF club membership – 5 CHF / hour pole rental Check out our schedule and enroll at http://cern.ch/club-fitness Hope to see you among us! 

  1. The relationship between active travel to school and health-related fitness in children and adolescents: a systematic review

    LENUS (Irish Health Repository)

    Lubans, David R

    2011-01-26

    Abstract Background Active travel to school (ATS) has been identified as an important source of physical activity for youth. However, the relationship between ATS and health-related fitness (HRF) among youth remains unclear. Methods A systematic search of seven electronic databases (EMBASE, OVID MEDLINE, PsycINFO, PubMed, Scopus, SPORTDiscus and TRIS on line) was conducted in December 2009 and studies published since 1980 were considered for inclusion. Results Twenty seven articles were identified that explored the relationship between ATS and the following aspects of HRF: weight status\\/body composition, cardiorespiratory fitness, muscular fitness and flexibility. Forty-eight percent of the studies that examined the relationship between ATS and weight status\\/body composition reported significant associations, this increased to 55% once poor quality studies were removed. Furthermore, the findings from five studies, including one longitudinal study, indicate that ATS is positively associated with cardiorespiratory fitness in youth. However, the evidence for the relationships between ATS and muscular fitness or flexibility is equivocal and limited by low study numbers. Conclusions There is some evidence to suggest that ATS is associated with a healthier body composition and level of cardiorespiratory fitness among youth. Strategies to increase ATS are warranted and should be included in whole-of-school approaches to the promotion of physical activity.

  2. The relationship between active travel to school and health-related fitness in children and adolescents: a systematic review

    Directory of Open Access Journals (Sweden)

    Kelly Paul

    2011-01-01

    Full Text Available Abstract Background Active travel to school (ATS has been identified as an important source of physical activity for youth. However, the relationship between ATS and health-related fitness (HRF among youth remains unclear. Methods A systematic search of seven electronic databases (EMBASE, OVID MEDLINE, PsycINFO, PubMed, Scopus, SPORTDiscus and TRIS on line was conducted in December 2009 and studies published since 1980 were considered for inclusion. Results Twenty seven articles were identified that explored the relationship between ATS and the following aspects of HRF: weight status/body composition, cardiorespiratory fitness, muscular fitness and flexibility. Forty-eight percent of the studies that examined the relationship between ATS and weight status/body composition reported significant associations, this increased to 55% once poor quality studies were removed. Furthermore, the findings from five studies, including one longitudinal study, indicate that ATS is positively associated with cardiorespiratory fitness in youth. However, the evidence for the relationships between ATS and muscular fitness or flexibility is equivocal and limited by low study numbers. Conclusions There is some evidence to suggest that ATS is associated with a healthier body composition and level of cardiorespiratory fitness among youth. Strategies to increase ATS are warranted and should be included in whole-of-school approaches to the promotion of physical activity.

  3. Entorhinal volume, aerobic fitness, and recognition memory in healthy young adults: A voxel-based morphometry study.

    Science.gov (United States)

    Whiteman, Andrew S; Young, Daniel E; Budson, Andrew E; Stern, Chantal E; Schon, Karin

    2016-02-01

    Converging evidence supports the hypothesis effects of aerobic exercise and environmental enrichment are beneficial for cognition, in particular for hippocampus-supported learning and memory. Recent work in humans suggests that exercise training induces changes in hippocampal volume, but it is not known if aerobic exercise and fitness also impact the entorhinal cortex. In animal models, aerobic exercise increases expression of growth factors, including brain derived neurotrophic factor (BDNF). This exercise-enhanced expression of growth hormones may boost synaptic plasticity, and neuronal survival and differentiation, potentially supporting function and structure in brain areas including but not limited to the hippocampus. Here, using voxel based morphometry and a standard graded treadmill test to determine cardio-respiratory fitness (Bruce protocol; ·VO2 max), we examined if entorhinal and hippocampal volumes were associated with cardio-respiratory fitness in healthy young adults (N=33). In addition, we examined if volumes were modulated by recognition memory performance and by serum BDNF, a putative marker of synaptic plasticity. Our results show a positive association between volume in right entorhinal cortex and cardio-respiratory fitness. In addition, average gray matter volume in the entorhinal cortex, bilaterally, was positively associated with memory performance. These data extend prior work on the cerebral effects of aerobic exercise and fitness to the entorhinal cortex in healthy young adults thus providing compelling evidence for a relationship between aerobic fitness and structure of the medial temporal lobe memory system.

  4. Cardiorespiratory and sensory responses to exercise in adults with mild cystic fibrosis.

    Science.gov (United States)

    Quon, Bradley S; Wilkie, Sabrina S; Molgat-Seon, Yannick; Schaeffer, Michele R; Ramsook, Andrew H; Wilcox, Pearce G; Guenette, Jordan A

    2015-12-01

    The purpose of this study was to evaluate cardiorespiratory fitness and reasons for exercise curtailment in a contemporary adult cystic fibrosis (CF) cohort with mild lung disease. Adults with mild CF (n = 19, forced expiratory volume in 1 s = 95 ± 17% predicted) were age-, sex-, ethnicity-, and body mass index-matched to healthy controls (n = 19) and underwent a detailed cardiopulmonary cycle exercise test. While CF subjects had a reduced peak oxygen uptake compared with controls, the values were normal when expressed as %predicted in 14/19 (74%) of subjects. Both groups demonstrated a normal cardiovascular limitation to exercise and stopped exercise primarily because of leg fatigue. Despite not being exercise-limited by respiratory factors, there was some evidence of ventilatory abnormalities as patients with mild CF had increased end-inspiratory lung volumes and reached an inflection/plateau in tidal volume relative to minute ventilation at lower exercise intensities compared with controls. Subjects with CF were not more likely to demonstrate expiratory flow limitation compared with controls and did not have evidence of dynamic hyperinflation during exercise. Despite increased end-inspiratory lung volumes and an earlier tidal volume inflection/plateau, CF subjects did not experience higher levels of dyspnea. In an exploratory analysis, a significant inverse correlation was observed between sweat chloride and peak work rate. Adult CF subjects with relatively well preserved spirometry have normal exercise performance relative to reference values and are primarily limited by nonrespiratory factors. However, ventilatory abnormalities were detected even in this mild CF cohort and should be evaluated in future therapeutic trials focused on disease-modifying therapies in mild CF. PMID:26429870

  5. Positional differences in the cardiorespiratory, autonomic, and somatic profiles of professional soccer players

    Directory of Open Access Journals (Sweden)

    Martin Semjon

    2016-06-01

    Full Text Available Background: In order to optimize training in soccer, knowledge about the specific position fitness demands and characteristics is required. Objective: The aim of the study was to determine whether there are position specific differences in somatic, cardiorespiratory and autonomic cardiac profiles of professional senior Czech soccer players. Methods: All players (N = 120 were divided into six groups according to field positions: goalkeeper (GK; n = 11, external defenders (ED; n = 15, central defenders (CD; n = 18, external midfielders (EM; n = 18, central midfielders (CM; n = 24 and forwards (F; n = 34. Players underwent anthropometrical and heart rate variability (HRV assessment, and a maximal incremental running test in order to obtain maximal oxygen uptake (VO2max and heart rate. HRV variables were transformed using the natural logarithm (Ln. Results: GK and CD were significantly (p = .005 heavier than ED, EM, CM, and F; while F were significantly (p = .026 heavier than CM and EM. GK and CD were significantly (p = .008 taller than ED, EM, CM, F; and EM were significantly (p = .041 shorter than CM and F. The only significant (p = .043 difference in percentage of body fat was observed in CD compared with CM. A significantly (p = .021 lower VO2max was observed for GK compared with ED, CD, EM, CM, and F. Supine HRV was significantly (p = .039 lower for Ln LF/HF in GK compared with F. Standing HRV was significantly (p = .03 lower for Ln LF in CD compared with both ED and F, significantly (p = .028 higher for Ln LF/HF in ED compared with CD and EM. Conclusions: In soccer, specific positions are associated with different height, body mass and aerobic capacity. A lower VO2max and vagal activity in GK compared with other playing positions may not be considered as disadvantage for performance in this specific playing position.

  6. Cardiorespiratory Effects of One-Legged High-Intensity Interval Training in Normoxia and Hypoxia: A Pilot Study.

    Science.gov (United States)

    Menz, Verena; Semsch, Mona; Mosbach, Florian; Burtscher, Martin

    2016-06-01

    A higher-than-average maximal oxygen consumption (VO2max), is closely associated with decreased morbidity and mortality and improved quality of life and acts as a marker of cardiorespiratory fitness. Although there is no consensus about an optimal training method to enhance VO2max, nevertheless training of small muscle groups and repeated exposure to hypoxia seem to be promising approaches. Therefore, this study was aimed at gaining innovative insights into the effects of small muscle group training in normoxia and hypoxia. Thirteen healthy participants were randomly assigned to the hypoxic (HG, n = 7) or normoxic (NG, n = 6) training group. Both groups completed nine high-intensity interval training sessions in 3 wks. The NG performed the training in normoxia (FiO2: 0.21; ~ 600 m) and the HG in hypoxia (FiO2: 0.126; ~ 4500 m). Each session consisted of 4 x 4 min one-legged cycling at 90% of maximal heart rate separated by 4 min recovery periods. Before and after the intervention period, VO2max and peak power output (Wmax) and responses to submaximal cycling (100 and 150 watts) were assessed in a laboratory cycling test. Peak power output significantly improved within both groups (9.6 ± 4.8% and 12.6 ± 8.9% for HG and NG, respectively) with no significant interaction (p = 0.277). However, VO2max only significantly increased after training in hypoxia from 45.4 ± 10.1 to 50.0 ± 9.8 ml/min/kg (10.8 ± 6.0%; p = 0.002) with no significant interaction (p = 0.146). The maximal O2-pulse improved within the HG and demonstrated a significant interaction (p = 0.040). One-legged cycling training significantly improved VO2max and peak power output. Training under hypoxic conditions may generate greater effects on VO2max than a similar training in normoxia and is considered as a promising training method for improving cardiorespiratory fitness. Key pointsNine sessions of one-legged high-intensity interval training significantly improved physical fitness.One-legged hypoxic

  7. Cardiorespiratory Effects of One-Legged High-Intensity Interval Training in Normoxia and Hypoxia: A Pilot Study.

    Science.gov (United States)

    Menz, Verena; Semsch, Mona; Mosbach, Florian; Burtscher, Martin

    2016-06-01

    A higher-than-average maximal oxygen consumption (VO2max), is closely associated with decreased morbidity and mortality and improved quality of life and acts as a marker of cardiorespiratory fitness. Although there is no consensus about an optimal training method to enhance VO2max, nevertheless training of small muscle groups and repeated exposure to hypoxia seem to be promising approaches. Therefore, this study was aimed at gaining innovative insights into the effects of small muscle group training in normoxia and hypoxia. Thirteen healthy participants were randomly assigned to the hypoxic (HG, n = 7) or normoxic (NG, n = 6) training group. Both groups completed nine high-intensity interval training sessions in 3 wks. The NG performed the training in normoxia (FiO2: 0.21; ~ 600 m) and the HG in hypoxia (FiO2: 0.126; ~ 4500 m). Each session consisted of 4 x 4 min one-legged cycling at 90% of maximal heart rate separated by 4 min recovery periods. Before and after the intervention period, VO2max and peak power output (Wmax) and responses to submaximal cycling (100 and 150 watts) were assessed in a laboratory cycling test. Peak power output significantly improved within both groups (9.6 ± 4.8% and 12.6 ± 8.9% for HG and NG, respectively) with no significant interaction (p = 0.277). However, VO2max only significantly increased after training in hypoxia from 45.4 ± 10.1 to 50.0 ± 9.8 ml/min/kg (10.8 ± 6.0%; p = 0.002) with no significant interaction (p = 0.146). The maximal O2-pulse improved within the HG and demonstrated a significant interaction (p = 0.040). One-legged cycling training significantly improved VO2max and peak power output. Training under hypoxic conditions may generate greater effects on VO2max than a similar training in normoxia and is considered as a promising training method for improving cardiorespiratory fitness. Key pointsNine sessions of one-legged high-intensity interval training significantly improved physical fitness.One-legged hypoxic

  8. Aerobic Fitness is Associated with Gray Matter Volume and White Matter Integrity in Multiple Sclerosis

    OpenAIRE

    Prakash, Ruchika Shaurya; Snook, Erin M.; Motl, Robert W.; Arthur F Kramer

    2009-01-01

    Alterations in gray and white matter have been well documented in individuals with multiple sclerosis. Severity and extent of such brain tissue damage have been associated with cognitive impairment, disease duration and neurological disability, making quantitative indices of tissue damage important markers of disease progression. In this study, we investigated the association between cardiorespiratory fitness and measures of gray matter atrophy and white matter integrity. Employing a voxel-ba...

  9. Autonomic control of cardiorespiratory interactions in fish, amphibians and reptiles.

    Science.gov (United States)

    Taylor, E W; Leite, C A C; Skovgaard, N

    2010-07-01

    Control of the heart rate and cardiorespiratory interactions (CRI) is predominantly parasympathetic in all jawed vertebrates, with the sympathetic nervous system having some influence in tetrapods. Respiratory sinus arrhythmia (RSA) has been described as a solely mammalian phenomenon but respiration-related beat-to-beat control of the heart has been described in fish and reptiles. Though they are both important, the relative roles of feed-forward central control and peripheral reflexes in generating CRI vary between groups of fishes and probably between other vertebrates. CRI may relate to two locations for the vagal preganglionic neurons (VPN) and in particular cardiac VPN in the brainstem. This has been described in representatives from all vertebrate groups, though the proportion in each location is variable. Air-breathing fishes, amphibians and reptiles breathe discontinuously and the onset of a bout of breathing is characteristically accompanied by an immediate increase in heart rate plus, in the latter two groups, a left-right shunting of blood through the pulmonary circuit. Both the increase in heart rate and opening of a sphincter on the pulmonary artery are due to withdrawal of vagal tone. An increase in heart rate following a meal in snakes is related to withdrawal of vagal tone plus a non-adrenergic-non-cholinergic effect that may be due to humoral factors released by the gut. Histamine is one candidate for this role.

  10. Screen time impairs the relationship between physical fitness and academic attainment in children

    Directory of Open Access Journals (Sweden)

    Macarena M. Aguilar

    2015-08-01

    Full Text Available OBJECTIVE: The purpose of this study was twofold: to analyze the association between physical fitness and academic attainment, and to determine the influence of screen time on the association between physical fitness and academic attainment.METHODS: A cross-sectional study including 395 schoolchildren from seven schools of the Maule Region, Chile (mean age 12.1 years; 50.4% boys participated in the autumn of 2014 (March to June. Self-reported physical activity and screen time were evaluated. The study measured academic achievement (mean of the grades obtained in several core subjects, physical fitness (cardiorespiratory fitness and muscular strength, weight, height, parental education, and socioeconomic status. Linear regression analysis was used to analyze the relationships between physical fitness and academic attainment after adjusting for potential confounders by gender. Analysis of variance was used to analyze the differences in academic attainment according to fitness and screen time categories (< 2 hours/day and ≥ 2 hours/day.RESULTS: In both genders good cardiorespiratory fitness levels were associated with high language (ß = 0.272-0.153 and mean academic attainment (ß = 0.192-0.156 grades; however, after adjusting for screen time and other potential confounders, these associations disappear. Similarly, no relationship was observed after analyzing those children who spend more hours of screen time (≥ 2 hours/day.CONCLUSIONS: Academic attainment is associated with higher cardiorespiratory fitness levels; however, it was weakly impaired by screen time. These findings seem to suggest that parents and policymakers should minimize the negative effects of screen time on children's lives to maximize the beneficial effect of healthy habits on academic attainment.

  11. Long-term exposure to gaseous air pollutants and cardio-respiratory mortality in Brisbane, Australia

    Directory of Open Access Journals (Sweden)

    Xiao Yu Wang

    2009-05-01

    Full Text Available This study examines the association of long-term exposure to gaseous air pollution with cardio-respiratory mortality in Brisbane, Australia, in the period 1996-2004. The pollutant concentrations were estimated using geographical information system (GIS techniques at the statistical local area (SLA level. The generalized estimating equations model was used to investigate the impact of nitrogen dioxide (NO2, ozone (O3 and sulphur dioxide (SO2 on mortality due to cardio-respiratory disease after adjusting for a range of potential confounders. An increase of 4.7% (95% confidence interval = 0.7-8.9% in cardio-respiratory mortality for 1 part per billion (ppb increment in annual average concentration of SO2 was estimated. However, there was no significant association between long-term exposures to NO2 or O3 and death due to cardio-respiratory disease. The results indicate that the annual average concentration of SO2 is associated with cardio-respiratory mortality at the SLA level and this association appears to vary with the geographical area.

  12. Cardiorespiratory phase-coupling is reduced in patients with obstructive sleep apnea.

    Directory of Open Access Journals (Sweden)

    Muammar M Kabir

    Full Text Available Cardiac and respiratory rhythms reveal transient phases of phase-locking which were proposed to be an important aspect of cardiorespiratory interaction. The aim of this study was to quantify cardio-respiratory phase-locking in obstructive sleep apnea (OSA. We investigated overnight polysomnography data of 248 subjects with suspected OSA. Cardiorespiratory phase-coupling was computed from the R-R intervals of body surface ECG and respiratory rate, calculated from abdominal and thoracic sensors, using Hilbert transform. A significant reduction in phase-coupling was observed in patients with severe OSA compared to patients with no or mild OSA. Cardiorespiratory phase-coupling was also associated with sleep stages and was significantly reduced during rapid-eye-movement (REM sleep compared to slow-wave (SW sleep. There was, however, no effect of age and BMI on phase coupling. Our study suggests that the assessment of cardiorespiratory phase coupling may be used as an ECG based screening tool for determining the severity of OSA.

  13. Effects of moderate and vigorous physical activity on fitness and body composition.

    Science.gov (United States)

    Drenowatz, Clemens; Prasad, Vivek K; Hand, Gregory A; Shook, Robin P; Blair, Steven N

    2016-08-01

    Current physical activity (PA) guidelines indicate that moderate-intensity (MPA) and vigorous intensity (VPA) PA provide similar benefits when total volume is equal. The present study examined the associations of MPA and VPA with body composition and cardiorespiratory fitness in free-living young adults. A total of 197 young adults (52.8 % male) were followed over a period of 15 months. Body composition was assessed via dual X-ray absorptiometry and time spent in various PA intensities was determined with a multi-sensor device every 3 months. Cardiorespiratory fitness was assessed with a graded exercise test at baseline and 15-months follow-up. Change in VPA was positively associated with cardiorespiratory fitness while MPA had beneficial associations with percent body fat. In overweight/obese participants the association with VO2peak was similar for MVPA bouts and VPA. Even though MPA and VPA have positive associations with overall health, their associations on key health parameters differ. PMID:27055817

  14. Physical Fitness and Mitochondrial Respiratory Capacity in Horse Skeletal Muscle

    OpenAIRE

    Votion, Dominique-Marie; Gnaiger, Erich; Lemieux, Hélène; Mouithys-Mickalad, Ange; Serteyn, Didier

    2012-01-01

    Background Within the animal kingdom, horses are among the most powerful aerobic athletic mammals. Determination of muscle respiratory capacity and control improves our knowledge of mitochondrial physiology in horses and high aerobic performance in general. Methodology/Principal Findings We applied high-resolution respirometry and multiple substrate-uncoupler-inhibitor titration protocols to study mitochondrial physiology in small (1.0–2.5 mg) permeabilized muscle fibres sampled from triceps ...

  15. A Profile of Fitness Parameters and Performance of Volleyball Players

    Directory of Open Access Journals (Sweden)

    Govind B. Taware

    2013-07-01

    Full Text Available Background: Ball games require comprehen-sive ability including physical, technical, men-tal and tactical abilities. Among them, physicalabilities of players exert marked effects on theskill of the players themselves and the tacticsof the team. Therefore players must have thephysical abilities to meet the demand of thesport. Volleyball is one of the most popularlyplayed games in the world. Unfortunately, thelevel of performance of the Indian volleyballplayers lags far behind the international stan-dards. Aim of the Study: The present study wasaimed to assess flexibility, muscular endurance,power and cardio-respiratory endurance of vol-leyball players and to compare the results withage matched controls. Also, to compare thefindings of the volleyball players with that ofthe international norms from the available lit-erature and to make some suggestions for theimprovement in their performance level. Ma-terial and Methods: The study was carried outin 40 male volleyball players aged between 17to 26 years and 40 ages matched male controls.Physical fitness parameters namely flexibility,muscular endurance, power and cardio-respi-ratory endurance were measured, data was ana-lyzed using unpaired ‘t’-test. Results: It was ob-served that all physical fitness parameters weresignificantly more in players as compared totheir aged-matched controls but when values ofthe subjects were compared to internationalstandards; our subjects were behind the recom-mended norms for the elite volleyball players.Conclusion: The volleyball players have moreadvantage of flexibility muscular endurance,power and cardio-respiratory endurance.

  16. Improving emotion recognition systems by embedding cardiorespiratory coupling

    International Nuclear Information System (INIS)

    This work aims at showing improved performances of an emotion recognition system embedding information gathered from cardiorespiratory (CR) coupling. Here, we propose a novel methodology able to robustly identify up to 25 regions of a two-dimensional space model, namely the well-known circumplex model of affect (CMA). The novelty of embedding CR coupling information in an autonomic nervous system-based feature space better reveals the sympathetic activations upon emotional stimuli. A CR synchrogram analysis was used to quantify such a coupling in terms of number of heartbeats per respiratory period. Physiological data were gathered from 35 healthy subjects emotionally elicited by means of affective pictures of the international affective picture system database. In this study, we finely detected five levels of arousal and five levels of valence as well as the neutral state, whose combinations were used for identifying 25 different affective states in the CMA plane. We show that the inclusion of the bivariate CR measures in a previously developed system based only on monovariate measures of heart rate variability, respiration dynamics and electrodermal response dramatically increases the recognition accuracy of a quadratic discriminant classifier, obtaining more than 90% of correct classification per class. Finally, we propose a comprehensive description of the CR coupling during sympathetic elicitation adapting an existing theoretical nonlinear model with external driving. The theoretical idea behind this model is that the CR system is comprised of weakly coupled self-sustained oscillators that, when exposed to an external perturbation (i.e. sympathetic activity), becomes synchronized and less sensible to input variations. Given the demonstrated role of the CR coupling, this model can constitute a general tool which is easily embedded in other model-based emotion recognition systems. (paper)

  17. The skeletal system

    NARCIS (Netherlands)

    Nikkels, PGJ

    2015-01-01

    Skeletal dysplasias are a group of disorders with a disturbance in development and/or growth of cartilage and/or bone. Epiphysis, metaphysis, and diaphysis of long bones are affected in a generalized manner with or without involvement of membranous bone of the skull. A dysostosis affects one or some

  18. Associations between different components of fitness and fatness with academic performance in Chilean youths

    Science.gov (United States)

    2016-01-01

    Objectives To analyze the associations between different components of fitness and fatness with academic performance, adjusting the analysis by sex, age, socio-economic status, region and school type in a Chilean sample. Methods Data of fitness, fatness and academic performance was obtained from the Chilean System for the Assessment of Educational Quality test for eighth grade in 2011 and includes a sample of 18,746 subjects (49% females). Partial correlations adjusted by confounders were done to explore association between fitness and fatness components, and between the academic scores. Three unadjusted and adjusted linear regression models were done in order to analyze the associations of variables. Results Fatness has a negative association with academic performance when Body Mass Index (BMI) and Waist to Height Ratio (WHR) are assessed independently. When BMI and WHR are assessed jointly and adjusted by cofounders, WHR is more associated with academic performance than BMI, and only the association of WHR is positive. For fitness components, strength was the variable most associated with the academic performance. Cardiorespiratory capacity was not associated with academic performance if fatness and other fitness components are included in the model. Conclusions Fitness and fatness are associated with academic performance. WHR and strength are more related with academic performance than BMI and cardiorespiratory capacity. PMID:27761345

  19. Aerobic Fitness is Associated with Gray Matter Volume and White Matter Integrity in Multiple Sclerosis

    Science.gov (United States)

    Prakash, Ruchika Shaurya; Snook, Erin M.; Motl, Robert W.; Kramer, Arthur F.

    2009-01-01

    Alterations in gray and white matter have been well documented in individuals with multiple sclerosis. Severity and extent of such brain tissue damage have been associated with cognitive impairment, disease duration and neurological disability, making quantitative indices of tissue damage important markers of disease progression. In this study, we investigated the association between cardiorespiratory fitness and measures of gray matter atrophy and white matter integrity. Employing a voxel-based approach to analyses of gray matter and white matter, we specifically examined whether higher levels of fitness in multiple sclerosis participants were associated with preserved gray matter volume and integrity of white matter. We found a positive association between cardiorespiratory fitness and regional gray matter volumes and higher focal fractional anisotropy values. Statistical mapping revealed that higher levels of fitness were associated with greater gray matter volume in the midline cortical structures including the medial frontal gyrus, anterior cingulate cortex and the precuneus. Further, we also found increasing levels of fitness were associated with higher fractional anisotropy in the left thalamic radiation and right anterior corona radiata. Both preserved gray matter volume and white-matter tract integrity were associated with better performance on measures of processing speed. Taken together, these results suggest that fitness exerts a prophylactic influence on the cerebral atrophy observed early on preserving neuronal integrity in multiple sclerosis, thereby reducing long-term disability. PMID:19560443

  20. fits2hdf: FITS to HDFITS conversion

    Science.gov (United States)

    Price, D. C.; Barsdell, B. R.; Greenhill, L. J.

    2015-05-01

    fits2hdf ports FITS files to Hierarchical Data Format (HDF5) files in the HDFITS format. HDFITS allows faster reading of data, higher compression ratios, and higher throughput. HDFITS formatted data can be presented transparently as an in-memory FITS equivalent by changing the import lines in Python-based FITS utilities. fits2hdf includes a utility to port MeasurementSets (MS) to HDF5 files.

  1. Association of breakfast consumption with objectively measured and self-reported physical activity, sedentary time and physical fitness in European adolescents: the HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) Study

    OpenAIRE

    Cuenca Garcia, Magdalena; Ruiz, Jonatan R.; Francisco B. Ortega; Labayen, Idoia; Gonzalez Gross, Maria Marcela; Moreno, Luis A.; Gomez Martinez, Sonia; Ciarapica, Donatella; Hallström, Lena; Wästlund, Acki; Molnar,, Dénes; Gottrand, Frederic; Manios, Yannis; Widhalm, Kurt; Kafatos, Anthony

    2013-01-01

    Objective To examine the association of breakfast consumption with objectively measured and self-reported physical activity, sedentary time and physical fitness. Design The HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) Cross-Sectional Study. Breakfast consumption was assessed by two non-consecutive 24 h recalls and by a ???Food Choices and Preferences??? questionnaire. Physical activity, sedentary time and physical fitness components (cardiorespiratory fitness, muscular ...

  2. A Cross-sectional Study of Resting Cardio-respiratory and Metabolic Changes in Pregnant Women.

    Science.gov (United States)

    Ajjimaporn, Amornpan; Somprasit, Charintip; Chaunchaiyakul, Rungchai

    2014-05-01

    [Purpose] We examined cardiorespiratory and metabolic changes across the 1st (G1), 2nd (G2) and 3rd (G3) trimesters in pregnant women. [Subjects and Methods] Forty-two healthy, active, non-smoking, pregnant women participated in this study. They were divided into G1, G2 and G3 groups depending on their mean gestational ages at the time of testing which were 10.5 ±2.9, 19.2 ±3.4, and 33.3 ±2.4 weeks of gestation, respectively. Cardio-respiratory and metabolic variables, VO2 (oxygen consumption), VCO2 (carbon dioxide production), and VE (minute ventilation), were measured using indirect calorimetry (IC, gas analyser) to estimate ventilatory equivalents of oxygen (VE/VO2) and carbon dioxide (VE/VCO2), RER (respiratory exchange ratio) and REE (resting energy expenditure). [Results] Women in the late pregnancy period had higher resting VCO2 and RER, whereas the VE/VCO2 ratio was significantly lower than in G1 and in G2. Even though the values of VO2 and REE increased throughout the course of pregnancy, no significant differences were found. [Conclusion] In pregnant women, resting cardiorespiratory and metabolic variables continuously changed throughout the 3 trimesters. Changes in VE/VCO2 and RER indicate shifting metabolic energy substrates. In addition, changes in cardiorespiratory variables, in parallel with gas exchange, indicate a better gas exchange process.

  3. Cardiorespiratory and Biomechanical Responses to Simulated Recreational Horseback Riding in Healthy Children

    Science.gov (United States)

    Rigby, Brandon R.; Papadakis, Zacharias; Bane, Annie A.; Park, Jin K.; Grandjean, Peter W.

    2015-01-01

    Purpose: The purpose of this study was to determine the reliability of cardiorespiratory and pelvic kinematic responses to simulated horseback riding (SHBR) and to characterize responses to SHBR relative to walking in apparently healthy children. Method: Fifteen healthy children (Mage = 9.5 ± 2.6 years) completed SHBR on a commercially available…

  4. VO[subscript 2] Prediction and Cardiorespiratory Responses during Underwater Treadmill Exercise

    Science.gov (United States)

    Greene, Nicholas P.; Greene, Elizabeth S.; Carbuhn, Aaron F.; Green, John S.; Crouse, Stephen F.

    2011-01-01

    We compared cardiorespiratory responses to exercise on an underwater treadmill (UTM) and land treadmill (LTM) and derived an equation to estimate oxygen consumption (VO[subscript 2]) during UTM exercise. Fifty-five men and women completed one LTM and five UTM exercise sessions on separate days. The UTM sessions consisted of chest-deep immersion,…

  5. Active Female Maximal and Anaerobic Threshold Cardiorespiratory Responses to Six Different Water Aerobics Exercises

    Science.gov (United States)

    Antunes, Amanda H.; Alberton, Cristine L.; Finatto, Paula; Pinto, Stephanie S.; Cadore, Eduardo L.; Zaffari, Paula; Kruel, Luiz F. M.

    2015-01-01

    Purpose: Maximal tests conducted on land are not suitable for the prescription of aquatic exercises, which makes it difficult to optimize the intensity of water aerobics classes. The aim of the present study was to evaluate the maximal and anaerobic threshold cardiorespiratory responses to 6 water aerobics exercises. Volunteers performed 3 of the…

  6. Transitions in Physiologic Coupling: Sleep Stage and Age Dependence of Cardio-respiratory Phase Synchronization

    Science.gov (United States)

    Bartsch, Ronny P.; Ivanov, Plamen Ch.

    2012-02-01

    Recent studies have focused on various features of cardiac and respiratory dynamics with the aim to better understand key aspects of the underlying neural control of these systems. We investigate how sleep influences cardio-respiratory coupling, and how the degree of this coupling changes with transitions across sleep stages in healthy young and elderly subjects. We analyze full night polysomnographic recordings of 189 healthy subjects (age range: 20 to 90 years). To probe cardio-respiratory coupling, we apply a novel phase synchronization analysis method to quantify the adjustment of rhythms between heartbeat and breathing signals. We investigate how cardio-respiratory synchronization changes with sleep-stage transitions and under healthy aging. We find a statistically significant difference in the degree of cardio-respiratory synchronization during different sleep stages for both young and elderly subjects and a significant decline of synchronization with age. This is a first evidence of how sleep regulation and aging influence a key nonlinear mechanism of physiologic coupling as quantified by the degree of phase synchronization between the cardiac and respiratory systems, which is of importance to develop adequate modeling approaches.

  7. Upper GI examinations in older premature infants with persistent apnea: Correlation with simultaneous cardiorespiratory monitoring

    International Nuclear Information System (INIS)

    Upper gastrointestinal examinations with simultaneous cardiorespiratory monitoring were performed in 39 older premature infants with persistent apnea. Swallowing incoordination was documented to be causatively related to persistent apnea in such infants, especially with feeding. Direct relationship between apnea and gastroesophageal reflux was not documented in this study. (orig.)

  8. Cardiorespiratory endurance evaluation using heart rate analysis during ski simulator exercise and the Harvard step test in elementary school students.

    Science.gov (United States)

    Lee, Hyo Taek; Roh, Hyo Lyun; Kim, Yoon Sang

    2016-01-01

    [Purpose] Efficient management using exercise programs with various benefits should be provided by educational institutions for children in their growth phase. We analyzed the heart rates of children during ski simulator exercise and the Harvard step test to evaluate the cardiopulmonary endurance by calculating their post-exercise recovery rate. [Subjects and Methods] The subjects (n = 77) were categorized into a normal weight and an overweight/obesity group by body mass index. They performed each exercise for 3 minutes. The cardiorespiratory endurance was calculated using the Physical Efficiency Index formula. [Results] The ski simulator and Harvard step test showed that there was a significant difference in the heart rates of the 2 body mass index-based groups at each minute. The normal weight and the ski-simulator group had higher Physical Efficiency Index levels. [Conclusion] This study showed that a simulator exercise can produce a cumulative load even when performed at low intensity, and can be effectively utilized as exercise equipment since it resulted in higher Physical Efficiency Index levels than the Harvard step test. If schools can increase sport durability by stimulating students' interests, the ski simulator exercise can be used in programs designed to improve and strengthen students' physical fitness.

  9. Skeletal (stromal) stem cells

    DEFF Research Database (Denmark)

    Abdallah, Basem M; Kermani, Abbas Jafari; Zaher, Walid;

    2015-01-01

    Skeletal (marrow stromal) stem cells (BMSCs) are a group of multipotent cells that reside in the bone marrow stroma and can differentiate into osteoblasts, chondrocytes and adipocytes. Studying signaling pathways that regulate BMSC differentiation into osteoblastic cells is a strategy....../preadipocyte factor 1 (Dlk1/Pref-1), the Wnt co-receptor Lrp5 and intracellular kinases. This article is part of a Special Issue entitled: Stem Cells and Bone....

  10. Beyond vascularization: aerobic fitness is associated with N-acetylaspartate and working memory.

    Science.gov (United States)

    Erickson, Kirk I; Weinstein, Andrea M; Sutton, Bradley P; Prakash, Ruchika Shaurya; Voss, Michelle W; Chaddock, Laura; Szabo, Amanda N; Mailey, Emily L; White, Siobhan M; Wojcicki, Thomas R; McAuley, Edward; Kramer, Arthur F

    2012-01-01

    Aerobic exercise is a promising form of prevention for cognitive decline; however, little is known about the molecular mechanisms by which exercise and fitness impacts the human brain. Several studies have postulated that increased regional brain volume and function are associated with aerobic fitness because of increased vascularization rather than increased neural tissue per se. We tested this position by examining the relationship between cardiorespiratory fitness and N-acetylaspartate (NAA) levels in the right frontal cortex using magnetic resonance spectroscopy. NAA is a nervous system specific metabolite found predominantly in cell bodies of neurons. We reasoned that if aerobic fitness was predominantly influencing the vasculature of the brain, then NAA levels should not vary as a function of aerobic fitness. However, if aerobic fitness influences the number or viability of neurons, then higher aerobic fitness levels might be associated with greater concentrations of NAA. We examined NAA levels, aerobic fitness, and cognitive performance in 137 older adults without cognitive impairment. Consistent with the latter hypothesis, we found that higher aerobic fitness levels offset an age-related decline in NAA. Furthermore, NAA mediated an association between fitness and backward digit span performance, suggesting that neuronal viability as measured by NAA is important in understanding fitness-related cognitive enhancement. Since NAA is found exclusively in neural tissue, our results indicate that the effect of fitness on the human brain extends beyond vascularization; aerobic fitness is associated with neuronal viability in the frontal cortex of older adults. PMID:22574272

  11. Associations of Fat Mass and Fat-Free Mass with Physical Fitness in 4-Year-Old Children: Results from the MINISTOP Trial.

    Science.gov (United States)

    Henriksson, Pontus; Cadenas-Sanchez, Cristina; Leppänen, Marja H; Delisle Nyström, Christine; Ortega, Francisco B; Pomeroy, Jeremy; Ruiz, Jonatan R; Löf, Marie

    2016-01-01

    Physical fitness is a powerful marker of health in youth. Studies in adolescents and adults suggest that higher fat mass is related to worse physical fitness. However, there is limited knowledge whether fat mass and fat-free mass are associated with physical fitness already in preschoolers. Baseline data from the MINISTOP (Mobile-based INtervention Intended to STop Obesity in Preschoolers) trial was utilized for this cross-sectional analysis. Body composition was assessed using air-displacement plethysmography. Fat mass index [fat mass (kg)/height² (m)] and fat-free mass index [fat-free mass (kg)/height² (m)] were used to provide height-adjusted measures of body composition. Physical fitness was measured using the PREFIT (FITness testing in PREschool children) battery, which assesses cardiorespiratory fitness, upper-body and lower-body muscular strength as well as motor fitness. In total, this study included 303 children (168 boys and 135 girls), who were on average 4.48 ± 0.15 years old. Higher fat mass index was associated with worse cardiorespiratory fitness (standardized β = -0.17, p = 0.002), lower-body muscular strength (β = -0.17, p = 0.003) and motor fitness (β = -0.21, p < 0.001) in regression analyses adjusted for age, sex and mutually adjusted for fat-mass index and fat-free mass index. Conversely, higher fat-free mass index was associated with better cardiorespiratory fitness (β = 0.18, p = 0.002), upper-body muscular strength (β = 0.39, p < 0.001), lower-body muscular strength (β = 0.22, p < 0.001) and motor fitness (β = 0.17, p = 0.004). Thus, fat mass and fat-free mass in preschoolers appear to have joint but opposite associations with physical fitness, an important marker for current and future health. PMID:27483320

  12. Skeletal surveys in multiple myeloma

    International Nuclear Information System (INIS)

    Thirty-three patients with multiple myeloma were studied with serial skeletal surveys, serum immunoglobulin levels, and postabsorptive urinary hydroxyproline (Spot-HYPRO) determinations. Twenty receiving chemotherapy were also followed with skeletal surveys in order to evaluate bone response to treatment. A close association was found between skeletal findings and changes in immunoglubulin levels with positive correlation in 71% of the patients. A similar association was found between skeletal disease and Spot-HYPRO level changes in 65%. Five of 12 patients (42%) with partial or complete clinical response to chemotherapy, demonstrated improvement in the appearance of skeletal lesions. Positive correlation between the roentgenographic changes and clinical markers of myeloma as well as therapeutic response, indicates that skeletal surveys are useful and effective in monitoring patients with multiple myeloma. (orig.)

  13. Markers of skeletal muscle mitochondrial function and lipid accumulation are moderately associated with the homeostasis model assessment index of insulin resistance in obese men.

    Directory of Open Access Journals (Sweden)

    Imtiaz A Samjoo

    Full Text Available Lower skeletal muscle mitochondrial oxidative phosphorylation capacity (OXPHOS and intramyocellular lipid (IMCL accumulation have been implicated in the etiology of insulin resistance (IR in obesity. The purpose of this study was to examine the impact of endurance exercise on biochemical and morphological measures of IMCL and mitochondrial content, and their relationship to IR in obese individuals. We examined mitochondrial content (subunit protein abundance and maximal activity of electron transport chain enzymes, IMCL/mitochondrial morphology in both subsarcolemmal (SS and intermyofibrillar (IMF regions by transmission electron microscopy, and intracellular lipid metabolites (diacylglycerol and ceramide in vastus lateralis biopsies, as well as, the homeostasis model assessment index of IR (HOMA-IR prior to and following twelve weeks of an endurance exercise regimen in healthy age- and physical activity-matched lean and obese men. Obese men did not show evidence of mitochondrial OXPHOS dysfunction, disproportionate IMCL content in sub-cellular regions, or diacylglycerol/ceramide accretion despite marked IR vs. lean controls. Endurance exercise increased OXPHOS and mitochondrial size and density, but not number of individual mitochondrial fragments, with moderate improvements in HOMA-IR. Exercise reduced SS IMCL content (size, number and density, increased IMF IMCL content, while increasing IMCL/mitochondrial juxtaposition in both regions. HOMA-IR was inversely associated with SS (r = -0.34; P = 0.051 and IMF mitochondrial density (r = -0.29; P = 0.096, IMF IMCL/mitochondrial juxtaposition (r = -0.30; P = 0.086, and COXII (r = -0.32; P = 0.095 and COXIV protein abundance (r = -0.35; P = 0.052; while positively associated with SS IMCL size (r = 0.28; P = 0.119 and SS IMCL density (r = 0.25; P = 0.152. Our findings suggest that once physical activity and cardiorespiratory fitness have been

  14. Cardiorespiratory control and cytokine profile in response to heat stress, hypoxia, and lipopolysaccharide (LPS) exposure during early neonatal period

    OpenAIRE

    McDonald, Fiona B.; Chandrasekharan, Kumaran; Wilson, Richard J.A.; Hasan, Shabih U.

    2016-01-01

    Abstract Sudden infant death syndrome (SIDS) is one of the most common causes of postneonatal infant mortality in the developed world. An insufficient cardiorespiratory response to multiple environmental stressors (such as prone sleeping positioning, overwrapping, and infection), during a critical period of development in a vulnerable infant, may result in SIDS. However, the effect of multiple risk factors on cardiorespiratory responses has rarely been tested experimentally. Therefore, this s...

  15. Effects of long-term dharma-chan meditation on cardiorespiratory synchronization and heart rate variability behavior.

    Science.gov (United States)

    Chang, Chih-Hao; Lo, Pei-Chen

    2013-04-01

    Remarkable changes in cardiorespiratory interactions are frequently experienced by Chan meditation practitioners following years of practice. This study compares the results of our study on cardiorespiratory interactions for novice (control group) and experienced (experimental group) Chan meditation practitioners. The effectual co-action between the cardiac and respiratory systems was evaluated by the degree of cardiorespiratory phase synchronization (CRPS). In addition, an adaptive-frequency-range (AFR) scheme to reliably quantify heart rate variability (HRV) was developed for assessing the regulation of sympathetic-parasympathetic activity and the efficiency of pulmonary gas exchange. The enhanced HRV method, named HRVAFR, can resolve the issue of overestimating HRV under the condition of slow respiration rates, which is frequently encountered in studies on Chan meditation practitioners. In the comparison of the three data sets collected from the two groups, our findings resulted in innovative hypotheses to interpret the extraordinary process of the rejuvenation of cardiorespiratory functions through long-term Dharma-Chan meditation practice. Particularly, advanced practitioners exhibit a continuously high degree of cardiorespiratory phase synchronization, even during rapid breathing. Based on our post-experimental interview with advanced practitioners, the activation of inner Chakra energy, during the course of Chan-detachment practice, frequently induces perceptible physiological-mental reformation, including an efficient mechanism for regulating cardiorespiratory interactions. PMID:23323597

  16. Distribution of Abdominal Obesity and Fitness Level in Overweight and Obese Korean Adults

    Directory of Open Access Journals (Sweden)

    Sue Kim

    2014-01-01

    Full Text Available Background. Abdominal obesity and its relative distribution are known to differ in association with metabolic characteristics and cardiorespiratory fitness. This study aimed to determine an association between fitness level and abdominal adiposity in overweight and obese adults. Methods. 228 overweight and obese individuals were classified as either cardiorespiratory unfit or fit based on their recovery heart rate. Visceral adipose tissue (VAT, subcutaneous adipose tissue (SAT, the visceral-to-subcutaneous adipose tissue ratio (VAT/SAT ratio, and cardiometabolic characteristics were analyzed to examine the relationship between recovery heart rate and abdominal adiposity components. Results. After adjustments for age and sex, significant relationships of recovery heart rate and VAT, SAT, and VAT/SAT ratio were found; however, SAT was not significantly associated after further adjustment for body mass index (BMI (r=0.045, P=0.499, whereas VAT (r=0.232, P<0.001 and VAT/SAT ratio (r=0.214, P=0.001 remained associated. Through stepwise multiple regression analyses after adjustment for age, sex, BMI, lifestyle factors, mean blood pressure, fasting glucose, HOMA-IR, lipid profiles, and hsCRP, recovery heart rate was identified as an independent variable associated with VAT (β=0.204, P<0.001 and VAT/SAT ratio (β=0.163, P=0.008 but not with SAT (β=0.097, P=0.111. Conclusions. Cardiorespiratory fitness level is independently associated with VAT and the VAT/SAT ratio but not with SAT in overweight and obese adults.

  17. Skeletal Effects of Smoking.

    Science.gov (United States)

    Cusano, Natalie E

    2015-10-01

    Smoking is a leading cause of preventable death and disability. Smoking has long been identified as a risk factor for osteoporosis, with data showing that older smokers have decreased bone mineral density and increased fracture risk compared to nonsmokers, particularly at the hip. The increase in fracture risk in smokers is out of proportion to the effects on bone density, indicating deficits in bone quality. Advanced imaging techniques have demonstrated microarchitectural deterioration in smokers, particularly in the trabecular compartment. The mechanisms by which smoking affects skeletal health remain unclear, although multiple pathways have been proposed. Smoking cessation may at least partially reverse the adverse effects of smoking on the skeleton.

  18. Skeletal Effects of Smoking.

    Science.gov (United States)

    Cusano, Natalie E

    2015-10-01

    Smoking is a leading cause of preventable death and disability. Smoking has long been identified as a risk factor for osteoporosis, with data showing that older smokers have decreased bone mineral density and increased fracture risk compared to nonsmokers, particularly at the hip. The increase in fracture risk in smokers is out of proportion to the effects on bone density, indicating deficits in bone quality. Advanced imaging techniques have demonstrated microarchitectural deterioration in smokers, particularly in the trabecular compartment. The mechanisms by which smoking affects skeletal health remain unclear, although multiple pathways have been proposed. Smoking cessation may at least partially reverse the adverse effects of smoking on the skeleton. PMID:26205852

  19. Survival, cardiorespiratory fitness and quality of life after renal transplantation in childhood: Data from the HENT study

    OpenAIRE

    2011-01-01

    Renal transplantation (tx) restores kidney function temporarily and improves the prospects of a normal life as compared to dialysis. During the last forty years great progress has been made in renal transplantation and its follow up treatment. However, preserving long-term graft function is still a major challenge. Therefore, it is crucial to review our practices in pediatric transplantation and to evaluate patient outcome as the first step in enhancing future prospects. Following renal tx a ...

  20. Association between Cardiorespiratory Fitness and Health-Related Quality of Life among Patients at Risk for Cardiovascular Disease in Uruguay.

    Directory of Open Access Journals (Sweden)

    Morgan N Clennin

    Full Text Available To examine the association between objectively measured CRF and physical and mental components of HRQoL in a Uruguayan cohort at risk for developing CVD.Patient data records from 2002-2012 at the Calidad de Vida Center were examined. To assess CRF, participants performed a submaximal exercise test. During the evaluation, participants also completed the SF-36, a HRQoL measure comprised of eight dimensions that are summarized by physical and mental component scores (PCS and MCS, respectively. ANCOVA was used to examine the relationship between HRQoL dimensions and CRF. Logistic regression was then used to compare the odds of having a HRQoL component score above the norm across CRF. All analyses were performed separately for males and females with additional stratified analyses across age and BMI conducted among significant trends.A total of 2,302 subjects were included in the analysis. Among females, a significant relationship was observed between CRF and vitality, physical functioning, physical role, bodily pain, and general health dimensions. However, for males the only dimension found to be significantly associated with CRF was physical health. After adjusting for potential confounders, a significant linear trend (p<0.001 for PCS scores above the norm across CRF levels was observed for females only.Among females with one or more risk factors for developing CVD, higher levels of CRF were positively associated with the vitality and physical dimensions of HRQoL, as well as the overall PCS. However, among males the only dimension associated with CRF was physical functioning. Future studies should examine this relationship among populations at risk for developing CVD in more detail and over time.

  1. Cardiorespiratory Fitness Levels among U.S. Youth Aged 12-15 Years: United States, 1999-2004 and 2012

    Science.gov (United States)

    ... KR, Eisenmann JC, Cureton KJ. Development of youth aerobic-capacity standards using receiver operating characteristic curves. Am J Prev Med 41(4 Suppl 2):S111–6. 2011. U.S. Department of Health ...

  2. Efficacy of multimodal exercise-based rehabilitation on physical activity, cardiorespiratory fitness, and patient-reported outcomes in cancer survivors

    DEFF Research Database (Denmark)

    Midtgaard, J; Christensen, Jesper Frank; Tolver, Anders;

    2013-01-01

    Sedentary behavior and impaired cardiovascular reserve capacity are common late effects of cancer therapy emphasizing the need for effective strategies to increase physical activity (PA) in cancer survivors. We examined the efficacy of a 12-month exercise-based rehabilitation program on self...

  3. DIFFERENCES IN PHYSICAL FITNESS AND CARDIOVASCULAR FUNCTION DEPEND ON BMI IN KOREAN MEN

    Directory of Open Access Journals (Sweden)

    Wi-Young So

    2010-06-01

    Full Text Available We investigated the associations between cardiovascular function and both body mass index and physical fitness in Korean men. The subjects were 2,013 men, aged 20 to 83 years, who visited a health promotion center for a comprehensive medical and fitness test during 2006-2009. The WHO's Asia-Pacific Standard Report definition of BMI was used in this study. Fitness assessment of cardiorespiratory endurance, muscular strength, muscular endurance, flexibility, power, agility, and balance were evaluated by VO2max (ml/kg/min, grip strength (kg, sit-ups (reps/min, sit and reach (cm, vertical jump (cm, side steps (reps/30s, and standing on one leg with eyes closed (sec, respectively. For cardiovascular function, we evaluated systolic blood pressure (SBP, diastolic blood pressure (DBP, resting heart rate (RHR, double product (DP, and vital capacity. There were significant decreases in cardiorespiratory endurance (p < 0.001, power (p < 0.001, and balance (p < 0.001, and increases in muscular strength (p < 0.001. Further, cardiovascular function, including SBP (p < 0.001, DBP (p < 0.001, double product (p < 0.001, and vital capacity (p=0.006 appeared to be lower for the obesity group. We conclude that an obese person exhibits lower fitness level and weaker cardiovascular function than a normal person

  4. Distribution of abdominal obesity and fitness level in overweight and obese korean adults.

    Science.gov (United States)

    Kim, Sue; Kim, Ji-Young; Lee, Duk-Chul; Lee, Hye-Sun; Lee, Ji-Won; Jeon, Justin Y

    2014-01-01

    Background. Abdominal obesity and its relative distribution are known to differ in association with metabolic characteristics and cardiorespiratory fitness. This study aimed to determine an association between fitness level and abdominal adiposity in overweight and obese adults. Methods. 228 overweight and obese individuals were classified as either cardiorespiratory unfit or fit based on their recovery heart rate. Visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), the visceral-to-subcutaneous adipose tissue ratio (VAT/SAT ratio), and cardiometabolic characteristics were analyzed to examine the relationship between recovery heart rate and abdominal adiposity components. Results. After adjustments for age and sex, significant relationships of recovery heart rate and VAT, SAT, and VAT/SAT ratio were found; however, SAT was not significantly associated after further adjustment for body mass index (BMI) (r = 0.045, P = 0.499), whereas VAT (r = 0.232, P fitness level is independently associated with VAT and the VAT/SAT ratio but not with SAT in overweight and obese adults. PMID:24723950

  5. The skeletal system

    International Nuclear Information System (INIS)

    The joy of diagnostic radiology is derived in great measure in its neverending variety including the unveiling of new diagnostic entities and new information concerning known disease processes. This year is no exception in the fascinating documentation of skeletal disease. In the study of disorders of the joints, CT investigation of the temporomandibular joint and arthotomography of the shoulder are gaining in popularity. New observations concerning cyst-like osseous lesions in lupus erthematosis, destructive joint lesions in renal osteodystrophy, and intra- and periarticular calcifications secondary to steroid injections have come forward. Articles discussing interesting observations concerning chondrosarcoma are included as well as one that describes the demonstration of fluid levels in aneurysmal bone cysts by CT. Ossification in soft tissues following resection of giant cell tumors as evidence of residual neoplasm is an important new sign. Marrow transplantation for treatment of mucopolysaccharidosis represents a new therapeutic breakthrough. Some of the skeletal manifestions of hypomagnesemia, 13-cis-retinoic acid, and aluminum are elucidated in this year's articles on metabolic disease. Further studies of methods of measuring bone density are also included

  6. Cardiorespiratory alterations in rodents experimentally envenomed with Hadruroides lunatus scorpion venom

    OpenAIRE

    Costal-Oliveira, Fernanda; Guerra-Duarte, Clara; Oliveira, Maira Souza; Castro, Karen Larissa Pereira de; Lopes-de-Sousa, Leticia; Lara, Aline; Gomes, Enéas Ricardo de Morais; Bonilla, Cesar; Guatimosim, Sílvia; Melo, Marília Martins; Chávez-Olórtegui, Carlos

    2016-01-01

    Background Hadruroides lunatus is the most abundant scorpion species in the Peruvian central coast, where most of the accidents involving humans are registered. In spite of its prevalence, there are only very few studies on H. lunatus envenomation. The aim of the present study was to analyze the cardiorespiratory alterations caused by H. lunatus envenomation in rodents. Methods Wistar rats injected with H. lunatus scorpion venom were submitted to electrocardiography. After euthanasia, rat lun...

  7. Economic evaluation of the benefits of reducing acute cardiorespiratory morbidity associated with air pollution

    Directory of Open Access Journals (Sweden)

    Anis Aslam H

    2002-12-01

    Full Text Available Abstract Background Few assessments of the costs and benefits of reducing acute cardiorespiratory morbidity related to air pollution have employed a comprehensive, explicit approach to capturing the full societal value of reduced morbidity. Methods We used empirical data on the duration and severity of episodes of cardiorespiratory disease as inputs to complementary models of cost of treatment, lost productivity, and willingness to pay to avoid acute cardiorespiratory morbidity outcomes linked to air pollution in epidemiological studies. A Monte Carlo estimation procedure was utilized to propagate uncertainty in key inputs and model parameters. Results Valuation estimates ranged from $13 (1997, Canadian (95% confidence interval, $0–28 for avoidance of an acute respiratory symptom day to $5,200 ($4,000–$6,400 for avoidance of a cardiac hospital admission. Cost of treatment accounted for the majority of the overall value of cardiac and respiratory hospital admissions as well as cardiac emergency department visits, while lost productivity generally represented a small proportion of overall value. Valuation estimates for days of restricted activity, asthma symptoms and acute respiratory symptoms were sensitive to alternative assumptions about level of activity restriction. As an example of the application of these values, we estimated that the observed decrease in particulate sulfate concentrations in Toronto between 1984 and 1999 resulted in annual benefits of $1.4 million (95% confidence interval $0.91–1.8 million in relation to reduced emergency department visits and hospital admissions for cardiorespiratory disease. Conclusion Our approach to estimating the value of avoiding a range of acute morbidity effects of air pollution addresses a number of limitations of the current literature, and is applicable to future assessments of the benefits of improving air quality.

  8. Chronic effects of strength training vs. Hydro aerobics on functional and cardiorespiratory ability in postmenopausal women.

    Science.gov (United States)

    Novaes, Giovanni S; Novaes, Jefferson S; Vilaça-Alves, José; Silva, Gabriel Costa E; Garrido, Nuno D; Furtado, Hélio; Reis, Victor M

    2014-09-29

    The current study aimed to compare the effects of two exercise programs (Strength Training and Hydro Gymnastics) on the functional and cardiorespiratory abilities of Portuguese postmenopausal women. The study population consisted of 38 volunteers (age: 66.9 ± 6.1 years, body mass: 73.70 ± 10.38 kg, and body height: 1.55 ± 0.10 m). Subjects were randomly divided into two experimental groups and one control group: one group performed 24 weeks of strength training (GST; n = 14), another performed 24 weeks of hydro gymnastics (GH; n = 17) and a control group (CG; n = 7), where the subjects continued with their regular daily activities without involvement in any physical exercise program. Three assessments were performed: before the beginning of the program, 12 weeks after the start of the training program and 24 weeks after the start of the program. To assess the functional ability of the participants, several tests proposed by Jones and Rikli (2002) were performed. To evaluate the cardiorespiratory ability of the participants, a modified treadmill Bruce test was applied. Significant differences (p<0.05) were found between the two training methods in the tests, which primarily demanded muscular strength. Body mass and the body mass index showed significant differences during the three stages of assessment in the GST group (p<0.05). With respect to the values that represent the variables of cardiorespiratory ability, positive and significant changes were observed in the two experimental groups. It was concluded that both exercise programs promoted improvements in some indicators of the functional and cardiorespiratory abilities of Portuguese postmenopausal women. PMID:25713645

  9. Chronic Effects of Strength Training Vs. Hydro Aerobics on Functional and Cardiorespiratory Ability in Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Novaes Giovanni S.

    2014-12-01

    Full Text Available The current study aimed to compare the effects of two exercise programs (Strength Training and Hydro Gymnastics on the functional and cardiorespiratory abilities of Portuguese postmenopausal women. The study population consisted of 38 volunteers (age: 66.9 ± 6.1 years, body mass: 73.70 ± 10.38 kg, and body height: 1.55 ± 0.10 m. Subjects were randomly divided into two experimental groups and one control group: one group performed 24 weeks of strength training (GST; n = 14, another performed 24 weeks of hydro gymnastics (GH; n = 17 and a control group (CG; n = 7, where the subjects continued with their regular daily activities without involvement in any physical exercise program. Three assessments were performed: before the beginning of the program, 12 weeks after the start of the training program and 24 weeks after the start of the program. To assess the functional ability of the participants, several tests proposed by Jones and Rikli (2002 were performed. To evaluate the cardiorespiratory ability of the participants, a modified treadmill Bruce test was applied. Significant differences (p<0.05 were found between the two training methods in the tests, which primarily demanded muscular strength. Body mass and the body mass index showed significant differences during the three stages of assessment in the GST group (p<0.05. With respect to the values that represent the variables of cardiorespiratory ability, positive and significant changes were observed in the two experimental groups. It was concluded that both exercise programs promoted improvements in some indicators of the functional and cardiorespiratory abilities of Portuguese postmenopausal women.

  10. Cardiorespiratory Mechanical Simulator for In Vitro Testing of Impedance Minute Ventilation Sensors in Cardiac Pacemakers.

    Science.gov (United States)

    Marcelli, Emanuela; Cercenelli, Laura

    2016-01-01

    We developed a cardiorespiratory mechanical simulator (CRMS), a system able to reproduce both the cardiac and respiratory movements, intended to be used for in vitro testing of impedance minute ventilation (iMV) sensors in cardiac pacemakers. The simulator consists of two actuators anchored to a human thorax model and a software interface to control the actuators and to acquire/process impedance signals. The actuators can be driven separately or simultaneously to reproduce the cardiac longitudinal shortening at a programmable heart rate and the diaphragm displacement at a programmable respiratory rate (RR). A standard bipolar pacing lead moving with the actuators and a pacemaker case fixed to the thorax model have been used to measure impedance (Z) variations during the simulated cardiorespiratory movements. The software is able to discriminate the low-frequency component because of respiration (Z(R)) from the high-frequency ripple because of cardiac effect (Z(C)). Impedance minute ventilation is continuously calculated from Z(R) and RR. From preliminary tests, the CRMS proved to be a reliable simulator for in vitro evaluation of iMV sensors. Respiration impedance recordings collected during cardiorespiratory movements reproduced by the CRMS were comparable in morphology and amplitude with in vivo assessments of transthoracic impedance variations. PMID:26501915

  11. Cardio-respiratory symptoms in panic disorder: a contribution from cognitive-behaviour therapy

    Directory of Open Access Journals (Sweden)

    Anna Lucia Spear King

    2011-01-01

    Full Text Available Objective: To compare patients with panic disorder with agoraphobia treated with cognitive-behavioural therapy (CBT associated with the medication with patients treated only with medication and verify the behaviour of the cardio-respiratory symptoms of both groups. Methods: Randomized sample in the Psychiatry Institute of the Federal University of Rio de Janeiro, divided in two groups of 25 participants each. Group 1 undertook 10 weekly sessions of CBT with one hour of duration each together with medication. Group 2, Control, were administered medication that only consisted of tricyclic anti-depressants and selective inhibitors of the re-uptake of serotonin. Evaluation instruments were applied at the beginning and to the end of the interventions. Results: According to the applied scales, group 1 showed statistically more significant results than group 2, with: reduction of panic attacks, cardio-respiratory symptoms, anticipatory anxiety, agoraphobia avoidance and fear of bodily sensations. Conclusion: Exposures (in vivo and interoceptive, especially for induction symptom exercises and relaxation, were considered essential to prepare patients with panic disorder to handle future cardio-respiratory symptoms and panic attacks with agoraphobia.

  12. Cardiorespiratory Mechanical Simulator for In Vitro Testing of Impedance Minute Ventilation Sensors in Cardiac Pacemakers.

    Science.gov (United States)

    Marcelli, Emanuela; Cercenelli, Laura

    2016-01-01

    We developed a cardiorespiratory mechanical simulator (CRMS), a system able to reproduce both the cardiac and respiratory movements, intended to be used for in vitro testing of impedance minute ventilation (iMV) sensors in cardiac pacemakers. The simulator consists of two actuators anchored to a human thorax model and a software interface to control the actuators and to acquire/process impedance signals. The actuators can be driven separately or simultaneously to reproduce the cardiac longitudinal shortening at a programmable heart rate and the diaphragm displacement at a programmable respiratory rate (RR). A standard bipolar pacing lead moving with the actuators and a pacemaker case fixed to the thorax model have been used to measure impedance (Z) variations during the simulated cardiorespiratory movements. The software is able to discriminate the low-frequency component because of respiration (Z(R)) from the high-frequency ripple because of cardiac effect (Z(C)). Impedance minute ventilation is continuously calculated from Z(R) and RR. From preliminary tests, the CRMS proved to be a reliable simulator for in vitro evaluation of iMV sensors. Respiration impedance recordings collected during cardiorespiratory movements reproduced by the CRMS were comparable in morphology and amplitude with in vivo assessments of transthoracic impedance variations.

  13. Unge, sundhed og fitness

    DEFF Research Database (Denmark)

    Jensen, Jens-Ole

    2003-01-01

    Artiklen redegør for udbredelsen af fitness blandt unge og diskuterer, hvor det er blevet så populært at dyrke fitness.......Artiklen redegør for udbredelsen af fitness blandt unge og diskuterer, hvor det er blevet så populært at dyrke fitness....

  14. Higher levels of cardiovascular fitness are associated with better executive function and prefrontal oxygenation in younger and older women

    Directory of Open Access Journals (Sweden)

    Olivier eDupuy

    2015-02-01

    Full Text Available Aim: Many studies have suggested that physical exercise training improves cognition and more selectively executive functions. There is a growing interest to clarify the neurophysiological mechanisms that underlie this effect. The aim of the current study was to evaluate the neurophysiological changes in cerebral oxygenation associated with physical fitness level and executive functions. Method: In this study, 22 younger and 36 older women underwent a maximal graded continuous test (i.e., O2max in order to classifyassign them into a fitness group (higher vs. lower fit. All participants completed neuropsychological paper and pencil testing and a computerized Stroop task (which contained executive and non-executive conditions in which the change in pPrefrontal cortex oxygenation change was evaluated in all participants with a near infrared spectroscopy (NIRS. system during a computerized Stroop task (which contains executive and non-executive conditions. Results: Our findings revealed a Fitness x Condition interaction (p < .05 such that higher fit women scored better on measures of executive functions than lower fit women. In comparison to lower fit women, higher fit women had faster reaction times in the switching (executiveExecutive condition of the computerized Stroop task. No significant effect was observed ion the non-executive condition of the test and no interactions were found with age. In measures of cerebral oxygenation (ΔHbT and ΔHbO2, we found a main effect of fitness on cerebral oxygenation during the Stroop task such that only high fit women demonstrated a significant increase in the right inferior frontal gyrus. Discussion/Conclusion:Higher fit individuals who demonstrate better cardiorespiratory functions (as measured by O2max show faster reaction times and greater cerebral oxygenation in the right inferior frontal gyrus than women with lower fitness levels. The lack of interaction with age, suggests that good

  15. Prediction of Skeletal Medial–Lateral for transfemoral ischial containment sockets

    Directory of Open Access Journals (Sweden)

    Michael P. Dillon, PhD

    2016-03-01

    Full Text Available Accurate measurement of the pelvis is critical for well-fitting and comfortable ischial containment sockets. The "Skeletal Medial-Lateral (ML" is intrusive and unreliable to measure in vivo. This study aimed to determine how accurately the Skeletal ML could be predicted and to identify which measurements were significant predictors. Computed tomography scans were randomly sampled from a cadaveric database (n = 200. Inclusion criteria were age > 20 yr; lower-limb alignment that replicated the anatomical position; and no evidence of osteological trauma, implants, or bony growths. Multivariate linear regression models were developed to predict the Skeletal ML based on a suite of independent variables, including sex, body mass, and distance between pelvic landmarks. The regression model explained 76% of the variance in the Skeletal ML (p < 0.001. Variables that contributed significantly to the prediction of the Skeletal ML (p < 0.05 included body mass, sex, inter-greater trochanter distance, pelvic depth, and age. Significant predictors of the Skeletal ML dimension characterize variation in subcutaneous adipose tissue thickness and pelvic morphology. The Skeletal ML could be predicted with relatively small errors (standard error of estimate = 7 mm that could be easily and reliably adjusted during socket fitting. Further research is needed to test the predictive tool in a real-world setting.

  16. Recommendations for FITS Headers

    OpenAIRE

    Hourclé, Joseph

    2012-01-01

    We present an example of best practices for FITS Headers to improve documentation and accessibility of solar physics data distributed as FITS files. We build on existing norms and standards, including ‘Proposed Keywords for SOHO’ and the FITS World Coordinate System (WCS) conventions, and include recommendations on the use of FITS features and extensions to help make data stored and distributed in FITS better suited for both present-day usage and for long-term archiving. O...

  17. Profile of body composition and cardiorrespiratory fitness in brazilian aeronauts. Perfil de la composición corporal y del condicionamiento cardiorrespiratorio en aeronautas militares brasileños.

    OpenAIRE

    Estélio Henrique Martin Dantas; Valéria Sales do Valle; Ana Cristina Lopes; Glória Barreto; Ângelo Marcelo Belas Coutinho

    2007-01-01

    AbstractThe objective of this study was to verify the profile of body composition and cardiorrespiratory fitness in brazilian military aeronauts, correlating them. The sample include 1550 aviators of the masculine sex (31,82 ± 9,70 years). The individuals were divided and classified in normal group (GN), overweight (GOW) and obesity (GOB) . It was realized an anthropometric and cardiorespiratory fitness evaluation. The Pearson correlation test was used to investigate the mean correlation, but...

  18. Cardiorespiratory control and cytokine profile in response to heat stress, hypoxia, and lipopolysaccharide (LPS) exposure during early neonatal period.

    Science.gov (United States)

    McDonald, Fiona B; Chandrasekharan, Kumaran; Wilson, Richard J A; Hasan, Shabih U

    2016-02-01

    Sudden infant death syndrome (SIDS) is one of the most common causes of postneonatal infant mortality in the developed world. An insufficient cardiorespiratory response to multiple environmental stressors (such as prone sleeping positioning, overwrapping, and infection), during a critical period of development in a vulnerable infant, may result in SIDS. However, the effect of multiple risk factors on cardiorespiratory responses has rarely been tested experimentally. Therefore, this study aimed to quantify the independent and possible interactive effects of infection, hyperthermia, and hypoxia on cardiorespiratory control in rats during the neonatal period. We hypothesized that lipopolysaccharide (LPS) administration will negatively impact cardiorespiratory responses to increased ambient temperature and hypoxia in neonatal rats. Sprague-Dawley neonatal rat pups were studied at postnatal day 6-8. Rats were examined at an ambient temperature of 33°C or 38°C. Within each group, rats were allocated to control, saline, or LPS (200 μg/kg) treatments. Cardiorespiratory and thermal responses were recorded and analyzed before, during, and after a hypoxic exposure (10% O2). Serum samples were taken at the end of each experiment to measure cytokine concentrations. LPS significantly increased cytokine concentrations (such as TNFα, IL-1β, MCP-1, and IL-10) compared to control. Our results do not support a three-way interaction between experimental factors on cardiorespiratory control. However, independently, heat stress decreased minute ventilation during normoxia and increased the hypoxic ventilatory response. Furthermore, LPS decreased hypoxia-induced tachycardia. Herein, we provide an extensive serum cytokine profile under various experimental conditions and new evidence that neonatal cardiorespiratory responses are adversely affected by dual interactions of environmental stress factors. PMID:26811056

  19. Axial skeletal CT densitometry

    International Nuclear Information System (INIS)

    Since the discovery of the Roentgen ray a precise and accurate assessment of bone mineral content has been a challenge to many investigators. A number of methods have been developed but no one satisfied. Considering its technical possibilities computed tomography is very promising in determination of bone mineral content (BMC). The new modality enables BMC estimations in the axial skeletal trabecular bone. CT densitometry can be performed on a normal commercially available third generation whole body CT scanner. No dedicated device in a special clinical set-up is necessary. In this study 106 patients, most of them clinically suspected of osteoporosis, were examined. The new method CT densitometry has been evaluated. The results have been correlated to alternative BMC determination methods. (Auth.)

  20. Pediatric aspects of skeletal dysplasia.

    Science.gov (United States)

    Ozono, Keiichi; Namba, Noriyuki; Kubota, Takuo; Kitaoka, Taichi; Miura, Kohji; Ohata, Yasuhisa; Fujiwara, Makoto; Miyoshi, Yoko; Michigami, Toshimi

    2012-10-01

    Skeletal dysplasia is a disorder of skeletal development characterized by abnormality in shape, length, a number and mineral density of the bone. Skeletal dysplasia is often associated with manifestation of other organs such as lung, brain and sensory systems. Skeletal dysplasias or dysostosis are classified with more than 400 different names. Enchondral bone formation is a coordinated event of chondrocyte proliferation, differentiation and exchange of terminally maturated chondrocyte with bone. Impaired enchondral bone formation will lead to skeletal dysplasia, especially associated with short long bones. Appropriate bone volume and mineral density are achieved by balance of bone formation and bone resorption and mineralization. The gene encoding fibroblast growth factor receptor 3 is responsible for achondroplasia, representative skeletal dysplasia with short stature. The treatment with growth hormone is approved for achondroplasia in Japan. Osteogenesis imperfecta is characterized by low bone mineral density and fragile bone. Data on the beneficial effect of bisphosphonate for osteogenesis imperfecta are accumulating. Osteopetrosis has high bone mineral density, but sometimes show bone fragility. In Japan as well as other countries, pediatrician treat larger numbers of patients with skeletal dysplasia with short stature and fragile bones compared to 20 years ago.

  1. Exploring the Relationship between Adiposity and Fitness in Young Children

    DEFF Research Database (Denmark)

    Egebæk, Heidi Klakk; Fairchild, Timothy J; Heidemann, Malene;

    2016-01-01

    PURPOSE: High levels of cardiorespiratory fitness (CRF) may attenuate the association between excessive adiposity and the risks of cardiovascular and metabolic disease. The purpose of this study was to stratify children according to their BMI and adiposity (body fat percentage, BF%) and compare...... levels of CRF across subgroups. METHODS: This prospective cohort study comprises a cross-sectional and longitudinal analyses of data collected at baseline (n=641) and two years later (n=579) on children (7.4-11.6y) attending public school in Denmark. Levels of CRF were measured using the Andersen test......, while BF% was measured by dual-energy x-ray absorptiometry (DXA). RESULTS: There were 560 (87.4%) children classified as normal weight according to BMI at baseline, of which 46 (7.4%) were identified as having excessive BF%. These children had significantly lower CRF (mean [95% Confidence Interval]: -63...

  2. An atlas of normal skeletal scintigraphy

    International Nuclear Information System (INIS)

    This atlas was compiled to provide the neophyte as well as the experienced radiologist and the nuclear medicine physician with a reference on normal skeletal scintigraphy as an aid in distinguishing normal variations in skeletal uptake from abnormal findings. Each skeletal scintigraph is labeled, and utilizing an identical scale, a relevant skeletal photograph and radiograph are placed adjacent to the scintigraph

  3. FIT3D: Fitting optical spectra

    Science.gov (United States)

    Sánchez, S. F.; Pérez, E.; Sánchez-Blázquez, P.; González, J. J.; Rosales-Ortega, F. F.; Cano-Díaz, M.; López-Cobá, C.; Marino, R. A.; Gil de Paz, A.; Mollá, M.; López-Sánchez, A. R.; Ascasibar, Y.; Barrera-Ballesteros, J.

    2016-09-01

    FIT3D fits optical spectra to deblend the underlying stellar population and the ionized gas, and extract physical information from each component. FIT3D is focused on the analysis of Integral Field Spectroscopy data, but is not restricted to it, and is the basis of Pipe3D, a pipeline used in the analysis of datasets like CALIFA, MaNGA, and SAMI. It can run iteratively or in an automatic way to derive the parameters of a large set of spectra.

  4. Reliability of Health-Related Physical Fitness Tests among Colombian Children and Adolescents: The FUPRECOL Study.

    Directory of Open Access Journals (Sweden)

    Robinson Ramírez-Vélez

    Full Text Available Substantial evidence indicates that youth physical fitness levels are an important marker of lifestyle and cardio-metabolic health profiles and predict future risk of chronic diseases. The reliability physical fitness tests have not been explored in Latino-American youth population. This study's aim was to examine the reliability of health-related physical fitness tests that were used in the Colombian health promotion "Fuprecol study". Participants were 229 Colombian youth (boys n = 124 and girls n = 105 aged 9 to 17.9 years old. Five components of health-related physical fitness were measured: 1 morphological component: height, weight, body mass index (BMI, waist circumference, triceps skinfold, subscapular skinfold, and body fat (% via impedance; 2 musculoskeletal component: handgrip and standing long jump test; 3 motor component: speed/agility test (4x10 m shuttle run; 4 flexibility component (hamstring and lumbar extensibility, sit-and-reach test; 5 cardiorespiratory component: 20-meter shuttle-run test (SRT to estimate maximal oxygen consumption. The tests were performed two times, 1 week apart on the same day of the week, except for the SRT which was performed only once. Intra-observer technical errors of measurement (TEMs and inter-rater (reliability were assessed in the morphological component. Reliability for the Musculoskeletal, motor and cardiorespiratory fitness components was examined using Bland-Altman tests. For the morphological component, TEMs were small and reliability was greater than 95% of all cases. For the musculoskeletal, motor, flexibility and cardiorespiratory components, we found adequate reliability patterns in terms of systematic errors (bias and random error (95% limits of agreement. When the fitness assessments were performed twice, the systematic error was nearly 0 for all tests, except for the sit and reach (mean difference: -1.03% [95% CI = -4.35% to -2.28%]. The results from this study indicate that the

  5. Cloverleaf skull associated with unusual skeletal anomalies

    International Nuclear Information System (INIS)

    A male infant which cloverleaf skull and multiple other birth defects born to unrelated, healthy, young parents is presented. Radiologic findings in addition to the cloverleaf skull configuration included short, wide clavicles, winged scapulae, unusual shapes of ribs with abnormal spacing between them and with prominent costovertebral junctions, and widely separated ischia. Ulnae appeared angular with probable fusion to the midportion of the radial bones bilaterally. There was polydactyly of the hands and feet with grossly abnormal metacarpal and metatarsal bones. Skeletal maturation was normal. Computed tomography of the skull showed dilated lateral and third ventricles as well as agenesis of the corpus callosum. The mother denies any teratogenic exposure during the pregnancy. The findings in this infant do not seem to fit into any previously described syndrome. (orig.)

  6. Fitness and Adiposity Are Independently Associated with Cardiometabolic Risk in Youth

    Directory of Open Access Journals (Sweden)

    Duncan S. Buchan

    2013-01-01

    Full Text Available Purpose. The purpose of the study was to examine the independent associations of adiposity and cardiorespiratory fitness with clustered cardiometabolic risk. Methods. A cross-sectional sample of 192 adolescents (118 boys, aged 14–16 years, was recruited from a South Lanarkshire school in the West of Scotland. Anthropometry and blood pressure were measured, and blood samples were taken. The 20 m multistage fitness test was the indicator of cardiorespiratory fitness (CRF. A clustered cardiometabolic risk score was constructed from HDL-C (inverted, LDL-C, HOMA, systolic blood pressure, and triglycerides. Interleukin-6, C-reactive protein, and adiponectin were also measured and examined relative to the clustered cardiometabolic risk score, CRF, and adiposity. Results. Although significant, partial correlations between BMI and waist circumference (WC and both CRF and adiponectin were negative and weak to moderate, while correlations between the BMI and WC and CRP were positive but weak to moderate. Weak to moderate negative associations were also evident for adiponectin with CRP, IL-6, and clustered cardiometabolic risk. WC was positively associated while CRF was negatively associated with clustered cardiometabolic risk. With the additional adjustment for either WC or CRF, the independent associations with cardiometabolic risk persisted. Conclusion. WC and CRF are independently associated with clustered cardiometabolic risk in Scottish adolescents.

  7. A Community-based Fitness and Mobility Exercise (FAME) Program for Older Adults with Chronic Stroke: a Randomized Controlled Trial

    Science.gov (United States)

    Pang, Marco Y.C.; Eng, Janice J.; Dawson, Andrew S.; McKay, Heather A.; Harris, Jocelyn E.

    2011-01-01

    OBJECTIVES To examine the effects of a community-based group exercise program for older individuals with chronic stroke. DESIGN Prospective, single-blind, randomized controlled intervention trial. SETTING Intervention was community-based. Data collection was performed in a research laboratory located in a rehabilitation hospital. PARTICIPANTS Sixty-three older individuals (≥50 years) with a chronic stroke (post-stroke duration ≥ 1 year) who were living in the community. INTERVENTION Participants were randomized into intervention group (n=32) or control group (n=31). The intervention group underwent a Fitness and Mobility Exercise (FAME) program designed to improve cardiorespiratory fitness, mobility, leg muscle strength, balance and hip bone mineral density (BMD) (1-hour sessions, 3 sessions/week, for 19 weeks). The control group underwent a seated upper extremity program. MEASUREMENTS (1) cardiorespiratory fitness (maximal oxygen consumption), (2) mobility (Six Minute Walk Test), (3) leg muscle strength (isometric knee extension), (4) balance (Berg Balance Scale), (5) activity and participation (Physical Activity Scale for Individuals with Physical Disabilities) and (6) femoral neck BMD (Dual-energy X-ray absorptiometry). RESULTS The intervention group had significantly more gains in cardiorespiratory fitness, mobility, and paretic leg muscle strength than controls. Femoral neck BMD of the paretic leg was maintained in the intervention group whereas a significant decline of the same occurred in controls. There was no significant time × group interaction for balance, activity and participation, non-paretic leg muscle strength and non-paretic femoral neck BMD. CONCLUSION The FAME program is feasible and beneficial for improving some of the secondary complications resulting from physical inactivity in older adults living with stroke. It may serve as a good model of community-based fitness program for preventing secondary diseases in older adults living with

  8. Neurology of endemic skeletal fluorosis

    Directory of Open Access Journals (Sweden)

    Reddy D

    2009-01-01

    Full Text Available Endemic skeletal fluorosis is widely prevalent in India and is a major public health problem. The first ever report of endemic skeletal fluorosis and neurological manifestation was from Prakasam district in Andhra Pradesh in the year 1937. Epidemiological and experimental studies in the endemic areas suggest the role of temperate climate, hard physical labor, nutritional status, presence of abnormal concentrations of trace elements like strontium, uranium, silica in water supplies, high fluoride levels in foods and presence of kidney disease in the development of skeletal fluorosis. Neurological complications of endemic skeletal fluorosis, namely radiculopathy, myelopathy or both are mechanical in nature and till date the evidence for direct neurotoxicity of fluoride is lacking. Prevention of the disease should be the aim, knowing the pathogenesis of fluorosis. Surgery has a limited role in alleviating the neurological disability and should be tailored to the individual based on the imaging findings.

  9. Simvastatin effects on skeletal muscle

    DEFF Research Database (Denmark)

    Larsen, Steen; Stride, Nis; Hey-Mogensen, Martin;

    2013-01-01

    Glucose tolerance and skeletal muscle coenzyme Q(10) (Q(10)) content, mitochondrial density, and mitochondrial oxidative phosphorylation (OXPHOS) capacity were measured in simvastatin-treated patients (n = 10) and in well-matched control subjects (n = 9)....

  10. Outdoor fitness routine

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000891.htm Outdoor fitness routine To use the sharing features on this ... you and is right for your level of fitness. Here are some ideas: Warm up first. Get ...

  11. Family Activities for Fitness

    Science.gov (United States)

    Grosse, Susan J.

    2009-01-01

    This article discusses how families can increase family togetherness and improve physical fitness. The author provides easy ways to implement family friendly activities for improving and maintaining physical health. These activities include: walking, backyard games, and fitness challenges.

  12. Pericapillary basement membrane thickening in human skeletal muscles.

    Science.gov (United States)

    Baum, Oliver; Bigler, Marius

    2016-09-01

    The basement membrane (BM) surrounding capillaries in skeletal muscles varies physiologically in thickness according to age, physical fitness, and anatomical site in humans. Furthermore, the pericapillary BM thickness (CBMT) increases pathophysiologically during several common disease states, including peripheral arterial disease and diabetes mellitus. This review on CBM thickening in human skeletal muscles is two pronged. First, it addresses the advantages/disadvantages of grid- and tablet-based measuring and morphometric techniques that are implemented to assess the CBMT on transmission electron micrographs. Second, it deals with the biology of CBM thickening in skeletal muscles, particularly its possible causes, molecular mechanisms, and functional impact. CBM thickening is triggered by several physical factors, including diabetes-associated glycation, hydrostatic pressure, and inflammation. Increased biosynthesis of type IV collagen expression or repetitive cycles in pericyte or endothelial cell degeneration/proliferation appear to be most critical for CBM accumulation. A thickened CBM obviously poses a greater barrier for diffusion, lowers the microvascular elasticity, and impedes transcytosis of inflammatory cells. Our own morphometric data reveal the CBM enlargement to be not accompanied by the pericyte coverage. Owing to an overlap or redundancy in the capillary supply, CBM thickening in skeletal muscles might not be such a devastating occurrence as in organs with endarterial circulation (e.g., kidney and retina). CBM growth in skeletal muscles can be reversed by training or administration of antidiabetic drugs. In conclusion, CBM thickening in skeletal muscles is a microvascular remodeling process by which metabolic, hemodynamic, and inflammatory forces are integrated together and which could play a hitherto underestimated role in etiology/progression of human diseases.

  13. Does CEO fitness matter?

    OpenAIRE

    Limbach, Peter; Sonnenburg, Florian

    2015-01-01

    This study provides evidence suggesting that CEOs' physical fitness has a positive impact on firm value, consistent with the beneficial effects of fitness on, e.g., cognitive functions, stress coping and job performance. For each of the years 2001 to 2011, we define S&P 1500 CEOs as fit if they finish a marathon. CEO fitness is also associated with higher firm profitability and higher M&A announcement returns. Our identification strategy includes CEO-firm fixed effects, instrumental variables...

  14. A methodological approach to short-term tracking of youth physical fitness: the Oporto Growth, Health and Performance Study.

    Science.gov (United States)

    Souza, Michele; Eisenmann, Joey; Chaves, Raquel; Santos, Daniel; Pereira, Sara; Forjaz, Cláudia; Maia, José

    2016-10-01

    In this paper, three different statistical approaches were used to investigate short-term tracking of cardiorespiratory and performance-related physical fitness among adolescents. Data were obtained from the Oporto Growth, Health and Performance Study and comprised 1203 adolescents (549 girls) divided into two age cohorts (10-12 and 12-14 years) followed for three consecutive years, with annual assessment. Cardiorespiratory fitness was assessed with 1-mile run/walk test; 50-yard dash, standing long jump, handgrip, and shuttle run test were used to rate performance-related physical fitness. Tracking was expressed in three different ways: auto-correlations, multilevel modelling with crude and adjusted model (for biological maturation, body mass index, and physical activity), and Cohen's Kappa (κ) computed in IBM SPSS 20.0, HLM 7.01 and Longitudinal Data Analysis software, respectively. Tracking of physical fitness components was (1) moderate-to-high when described by auto-correlations; (2) low-to-moderate when crude and adjusted models were used; and (3) low according to Cohen's Kappa (κ). These results demonstrate that when describing tracking, different methods should be considered since they provide distinct and more comprehensive views about physical fitness stability patterns. PMID:26890706

  15. Aneuploidy and Skeletal Health

    Science.gov (United States)

    Kamalakar, Archana; Harris, John R.; McKelvey, Kent D.; Suva, Larry J.

    2014-01-01

    The normal human chromosome complement consists of 46 chromosomes comprising 22 morphologically different pairs of autosomes and one pair of sex chromosomes. Variations in either chromosome number and/or structure frequently result in significant mental impairment, and/or a variety of other clinical problems, among them, altered bone mass and strength. Chromosomal syndromes associated with specific chromosomal abnormalities are classified as either numerical or structural and may involve more than one chromosome. Aneuploidy refers to the presence of an extra copy of a specific chromosome, or trisomy, as seen in Down’s syndrome (trisomy 21), or the absence of a single chromosome, or monosomy, as seen in Turner syndrome (a single X chromosome in females: 45, X). Aneuploidies have diverse phenotypic consequences, ranging from severe mental retardation and developmental abnormalities to increased susceptibility to various neoplasms and premature death. In fact, trisomy 21 is the prototypical aneuploidy in humans, is the most common genetic abnormality associated with longevity and is one of the most widespread genetic causes of intellectual disability. In this review, the impact of trisomy 21 on the bone mass, architecture, skeletal health and quality of life of people with Down syndrome will be discussed. PMID:24980541

  16. Quasispecies on Fitness Landscapes.

    Science.gov (United States)

    Schuster, Peter

    2016-01-01

    Selection-mutation dynamics is studied as adaptation and neutral drift on abstract fitness landscapes. Various models of fitness landscapes are introduced and analyzed with respect to the stationary mutant distributions adopted by populations upon them. The concept of quasispecies is introduced, and the error threshold phenomenon is analyzed. Complex fitness landscapes with large scatter of fitness values are shown to sustain error thresholds. The phenomenological theory of the quasispecies introduced in 1971 by Eigen is compared to approximation-free numerical computations. The concept of strong quasispecies understood as mutant distributions, which are especially stable against changes in mutations rates, is presented. The role of fitness neutral genotypes in quasispecies is discussed.

  17. Skeletal muscle as a regulator of the longevity protein, Klotho

    Directory of Open Access Journals (Sweden)

    Keith G Avin

    2014-06-01

    Full Text Available Klotho is a powerful longevity protein that has been linked to the prevention of muscle atrophy, osteopenia, and cardiovascular disease. Similar anti-aging effects have also been ascribed to exercise and physical activity. While an association between muscle function and klotho expression has been previously suggested from longitudinal cohort studies, a direct relationship between circulating klotho and skeletal muscle has not been investigated. In this paper, we present a review of the literature and preliminary evidence that, together, suggests klotho expression may be modulated by skeletal muscle activity. Our pilot clinical findings performed in young and aged individuals suggest that circulating klotho levels are upregulated in response to an acute exercise bout, but that the response may be dependent on fitness level. A similar upregulation of circulating klotho is also observed in response to an acute exercise in young and old mice, suggesting this may be a good model for mechanistically probing the role of physical activity on klotho expression. Finally, we highlight overlapping signaling pathways that are modulated by both klotho and skeletal muscle and propose potential mechanisms for cross-talk between the two. It is hoped that this review will stimulate further consideration of the relationship between skeletal muscle activity and klotho expression, potentially leading to important insights into the well-documented systemic anti-aging effects of exercise.

  18. Chronic Effects of Strength Training Vs. Hydro Aerobics on Functional and Cardiorespiratory Ability in Postmenopausal Women

    OpenAIRE

    Novaes Giovanni S.; Novaes Jefferson S.; Vilaça-Alves José; Costa e Silva Gabriel; Garrido Nuno D.; Furtado Hélio; Reis Victor M.

    2014-01-01

    The current study aimed to compare the effects of two exercise programs (Strength Training and Hydro Gymnastics) on the functional and cardiorespiratory abilities of Portuguese postmenopausal women. The study population consisted of 38 volunteers (age: 66.9 ± 6.1 years, body mass: 73.70 ± 10.38 kg, and body height: 1.55 ± 0.10 m). Subjects were randomly divided into two experimental groups and one control group: one group performed 24 weeks of strength training (GST; n = 14), another performe...

  19. Change urgent adaptation reaction cardiorespiratory system under the influence of experimental program of the training means in sport dance

    Directory of Open Access Journals (Sweden)

    Lee Bo

    2010-09-01

    Full Text Available Possibilities of increase of function of cardiorespiratory system of dancers are rotined. 24 sportsmen took part in research (12 pair. Directions of strengthening the function of aerobic energy-supply, optimizations of physiological properties of the cardiorespiratory system of organism, are set. The terms of increase of the special capacity are formed. The terms of activation of function of indemnification of increasing acidemia changes and developing on this basis fatigue are offered. Application of the program of trainings facilities specifies on the increase of kinetics and stability of reaction of frequency of heart-throbs.

  20. Perceived sports competence mediates the relationship between childhood motor skill proficiency and adolescent physical activity and fitness: a longitudinal assessment

    Directory of Open Access Journals (Sweden)

    van Beurden Eric

    2008-08-01

    Full Text Available Abstract Background The purpose of this paper was to investigate whether perceived sports competence mediates the relationship between childhood motor skill proficiency and subsequent adolescent physical activity and fitness. Methods In 2000, children's motor skill proficiency was assessed as part of a school-based physical activity intervention. In 2006/07, participants were followed up as part of the Physical Activity and Skills Study and completed assessments for perceived sports competence (Physical Self-Perception Profile, physical activity (Adolescent Physical Activity Recall Questionnaire and cardiorespiratory fitness (Multistage Fitness Test. Structural equation modelling techniques were used to determine whether perceived sports competence mediated between childhood object control skill proficiency (composite score of kick, catch and overhand throw, and subsequent adolescent self-reported time in moderate-to-vigorous physical activity and cardiorespiratory fitness. Results Of 928 original intervention participants, 481 were located in 28 schools and 276 (57% were assessed with at least one follow-up measure. Slightly more than half were female (52.4% with a mean age of 16.4 years (range 14.2 to 18.3 yrs. Relevant assessments were completed by 250 (90.6% students for the Physical Activity Model and 227 (82.3% for the Fitness Model. Both hypothesised mediation models had a good fit to the observed data, with the Physical Activity Model accounting for 18% (R2 = 0.18 of physical activity variance and the Fitness Model accounting for 30% (R2 = 0.30 of fitness variance. Sex did not act as a moderator in either model. Conclusion Developing a high perceived sports competence through object control skill development in childhood is important for both boys and girls in determining adolescent physical activity participation and fitness. Our findings highlight the need for interventions to target and improve the perceived sports competence of youth.

  1. Skeletal muscle involvement in cardiomyopathies.

    Science.gov (United States)

    Limongelli, Giuseppe; D'Alessandro, Raffaella; Maddaloni, Valeria; Rea, Alessandra; Sarkozy, Anna; McKenna, William J

    2013-12-01

    The link between heart and skeletal muscle disorders is based on similar molecular, anatomical and clinical features, which are shared by the 'primary' cardiomyopathies and 'primary' neuromuscular disorders. There are, however, some peculiarities that are typical of cardiac and skeletal muscle disorders. Skeletal muscle weakness presenting at any age may indicate a primary neuromuscular disorder (associated with creatine kinase elevation as in dystrophinopathies), a mitochondrial disease (particularly if encephalopathy, ocular myopathy, retinitis, neurosensorineural deafness, lactic acidosis are present), a storage disorder (progressive exercise intolerance, cognitive impairment and retinitis pigmentosa, as in Danon disease), or metabolic disorders (hypoglycaemia, metabolic acidosis, hyperammonaemia or other specific biochemical abnormalities). In such patients, skeletal muscle weakness usually precedes the cardiomyopathy and dominates the clinical picture. Nevertheless, skeletal involvement may be subtle, and the first clinical manifestation of a neuromuscular disorder may be the occurrence of heart failure, conduction disorders or ventricular arrhythmias due to cardiomyopathy. ECG and echocardiogram, and eventually, a more detailed cardiovascular evaluation may be required to identify early cardiac involvement. Paediatric and adult cardiologists should be proactive in screening for neuromuscular and related disorders to enable diagnosis in probands and evaluation of families with a focus on the identification of those at risk of cardiac arrhythmia and emboli who may require specific prophylactic treatments, for example, pacemaker, implantable cardioverter-defibrillator and anticoagulation. PMID:24149064

  2. The discriminatory value of cardiorespiratory interactions in distinguishing awake from anaesthetised states: a randomised observational study.

    Science.gov (United States)

    Kenwright, D A; Bernjak, A; Draegni, T; Dzeroski, S; Entwistle, M; Horvat, M; Kvandal, P; Landsverk, S A; McClintock, P V E; Musizza, B; Petrovčič, J; Raeder, J; Sheppard, L W; Smith, A F; Stankovski, T; Stefanovska, A

    2015-12-01

    Depth of anaesthesia monitors usually analyse cerebral function with or without other physiological signals; non-invasive monitoring of the measured cardiorespiratory signals alone would offer a simple, practical alternative. We aimed to investigate whether such signals, analysed with novel, non-linear dynamic methods, would distinguish between the awake and anaesthetised states. We recorded ECG, respiration, skin temperature, pulse and skin conductivity before and during general anaesthesia in 27 subjects in good cardiovascular health, randomly allocated to receive propofol or sevoflurane. Mean values, variability and dynamic interactions were determined. Respiratory rate (p = 0.0002), skin conductivity (p = 0.03) and skin temperature (p = 0.00006) changed with sevoflurane, and skin temperature (p = 0.0005) with propofol. Pulse transit time increased by 17% with sevoflurane (p = 0.02) and 11% with propofol (p = 0.007). Sevoflurane reduced the wavelet energy of heart (p = 0.0004) and respiratory (p = 0.02) rate variability at all frequencies, whereas propofol decreased only the heart rate variability below 0.021 Hz (p < 0.05). The phase coherence was reduced by both agents at frequencies below 0.145 Hz (p < 0.05), whereas the cardiorespiratory synchronisation time was increased (p < 0.05). A classification analysis based on an optimal set of discriminatory parameters distinguished with 95% success between the awake and anaesthetised states. We suggest that these results can contribute to the design of new monitors of anaesthetic depth based on cardiovascular signals alone. PMID:26350998

  3. Prevalence of heartworm infection in cats with signs of cardiorespiratory abnormalities

    International Nuclear Information System (INIS)

    To determine prevalence of heartworm infection in a population of pet cats with cardiorespiratory abnormalities and to determine relative usefulness of clinical signs and tests in diagnosis of heartworm disease. Prospective case series. 100 client-owned cats with clinical signs of cardiorespiratory abnormalities. Cats were evaluated using CBC, modified Knott test, ELISA for serologic detection of heartworm antigen and antibodies to heartworms, thoracic radiography, and echocardiography. Cats were considered infected if they had circulating microfilaria, heartworm antigens in serum, or if heartworms were detected by echocardiography or on necropsy. Cats were considered suspicious for infection if they had 2 of the following: serum antibodies to heartworms, eosinophilia or basophilia, or indicative radiographic findings. 9 cats were infected with heartworms, resulting in a prevalence of 9%; 26 cats had evidence of heartworm exposure (i.e., serum antibodies to heartworms). Twenty cats were considered suspicious for heartworm infection. Some outdoor exposure was reported twice as often in heartworm-infected cats, compared with noninfected and suspicious cats. However, a third of infected cats were reportedly housed totally indoors. Cough and dyspnea were strong indicators of heartworm disease. Eight of 9 infected cats had serum antibodies to heartworms and heartworm antigen in serum. Thoracic radiography and echocardiography indicated heartworm infection in 6 and 7 of the 9 cats, respectively. Cough or dyspnea may indicate heartworm disease in cats; serologic tests, echocardiography, and radiography are most useful diagnostic procedures. Although living indoors is protective, it may not preclude heartworm infection in cats

  4. Is flourishing good for the heart?: relationships between positive psychology characteristics and cardiorespiratory health

    Directory of Open Access Journals (Sweden)

    Barna Konkoly Thege

    2015-01-01

    Full Text Available The purpose of this study was to provide further data on the relationships between positive psychology constructs and cardiorespiratory parameters including arterial stiffness indicators. Hypotheses were tested cross-sectionally on a sample of patients with cardiovascular disease and on a healthy sample. Life satisfaction, psychological well-being, optimism, meaning in life, and sense of coherence were included as psychological indicators, while peripheral and central blood pressure, arterial stiffness, and heart cycle and respiratory function parameters were used as physiological variables. Most of the associations examined were not significant in either sample, with some notable exceptions (the direction of these linear relationships was in accordance with our expectations. Satisfaction with life was related to lower peripheral systolic and mean arterial blood pressure in the clinical sample. Further, sense of coherence was positively associated with forced expiratory volume. In the healthy sample, the augmentation indexes and aortic systolic blood pressure were negatively associated with optimism. However, none of the linear and non-linear relationships proved to be significant in either of the samples when using the Bonferroni correction. Further research should determine whether the present findings derive from the cultural characteristics of our samples or whether the mediators between flourishing and cardiorespiratory health should be sought among other variables than the ones included in the present investigation.

  5. Effects of Loma morhua (Microsporidia) infection on the cardiorespiratory performance of Atlantic cod Gadus morhua (L).

    Science.gov (United States)

    Powell, M D; Gamperl, A K

    2016-02-01

    The microsporidian Loma morhua infects Atlantic cod (Gadus morhua) in the wild and in culture and results in the formation of xenomas within the gill filaments, heart and spleen. Given the importance of the two former organs to metabolic capacity and thermal tolerance, the cardiorespiratory performance of cod with a naturally acquired infection of Loma was measured during an acute temperature increase (2 °C h(-1) ) from 10 °C to the fish's critical thermal maximum (CTMax ). In addition, oxygen consumption and swimming performance were measured during two successive critical swimming speed (Ucrit ) tests at 10 °C. While Loma infection had a negative impact on cod cardiac function at warm temperatures, and on metabolic capacity in both the CTMax and Ucrit tests (i.e. a reduction of 30-40%), it appears that the Atlantic cod can largely compensate for these Loma-induced cardiorespiratory limitations. For example, (i) CTMax (21.0 ± 0.3 °C) and Ucrit (~1.75 BL s(-1) ) were very comparable to those reported in previous studies using uninfected fish from the same founder population; and (ii) our data suggest that tissue oxygen extraction, and potentially the capacity for anaerobic metabolism, is enhanced in fish infected with this microsporidian. PMID:25683657

  6. Cardiorespiratory effects of intravenous bolus administration and infusion of ketamine-midazolam in dogs.

    Science.gov (United States)

    Jacobson, J D; Hartsfield, S M

    1993-10-01

    Twelve healthy dogs were used to determine the cardiorespiratory effects of i.v. administered ketamine (10 mg/kg of body weight) and midazolam (0.5 mg/kg). Half the dogs received a ketamine-midazolam combination (K-M) as a bolus over 30 seconds and the other half received the K-M as an infusion over 15 minutes. Induction of anesthesia by use of K-M was good in all dogs. Ketamine-midazolam combination as a bolus or infusion induced minimal cardiorespiratory effects, except for significant (P dogs of the infusion group. Mild and transient respiratory depression was observed in dogs of both groups immediately after administration of K-M, but was greater in dogs of the bolus group than in dogs of the infusion group. Duration of action of K-M for chemical restraint was short. Salivation and defecation were observed in a few dogs. Extreme muscular tone developed in 1 dog after K-M bolus administration. PMID:8250397

  7. Cardiorespiratory and neuromuscular responses during water aerobics exercise performed with and without equipment.

    Science.gov (United States)

    Pinto, S S; Cadore, E L; Alberton, C L; Silva, E M; Kanitz, A C; Tartaruga, M P; Kruel, L F M

    2011-12-01

    The aim of the study was to compare the cardiorespiratory and neuromuscular responses to water aerobics exercise performed with and without equipment. 15 women performed stationary jogging combined with elbow flexion/extension without equipment, with water-drag forces equipment and with water-floating equipment, at 2 submaximal cadences and at maximal cadence. Heart rate, oxygen uptake and electromyographic signal from biceps brachii, triceps brachii, biceps femoris and rectus femoris were collected during the exercise. The heart rate and oxygen uptake showed significantly higher values during the execution of the water aerobics exercise with either equipment compared to the execution without equipment. In addition, significant difference was found between submaximal cadences. For neuromuscular responses, no significant differences were found between the submaximal cadences for all muscles analyzed; however, significant differences were found between these submaximal cadences and the maximal cadence. Similarly, the results showed no significant differences between the execution of the exercise with or without equipment, except in the muscle activation of triceps brachii and biceps femoris, which was higher when using water-floating and water-drag forces equipment, respectively. In conclusion, the water aerobics exercise presented higher cardiorespiratory responses with equipment and also increased the cadence of execution. Nevertheless, neuromuscular responses were higher only at maximal cadence. PMID:22052026

  8. The effect of adenotonsillectomy for childhood sleep apnoea on cardiorespiratory control

    Directory of Open Access Journals (Sweden)

    Mathias Baumert

    2016-06-01

    Full Text Available The efficacy of adenotonsillectomy for relieving obstructive sleep apnoea symptoms in children has been firmly established, but its precise effects on cardiorespiratory control are poorly understood. In 375 children enrolled in the Childhood Adenotonsillectomy Trial, randomised to undergo either adenotonsillectomy (n=194 or a strategy of watching waiting (n=181, respiratory rate, respiratory sinus arrhythmia and heart rate were analysed during quiet, non-apnoeic and non-hypopnoeic breathing throughout sleep at baseline and at 7 months using overnight polysomnography. Children who underwent early adenotonsillectomy demonstrated an increase in respiratory rate post-surgery while the watchful waiting group showed no change. Heart rate and respiratory sinus arrhythmia were comparable between both arms. On assessing cardiorespiratory variables with regard to normalisation of clinical polysomnography findings during follow-up, heart rate was reduced in children who had resolution of obstructive sleep apnoea syndrome, while no differences in their respiratory rate or respiratory sinus arrhythmia were observed. Adenotonsillectomy for obstructive sleep apnoea increases baseline respiratory rate during sleep. Normalisation of apnoea–hypopnoea index, spontaneously or via surgery, lowers heart rate. Considering the small average effect size, the clinical significance is uncertain.

  9. Red fox (Vulpes vulpes) as a potential reservoir host of cardiorespiratory parasites in Bosnia and Herzegovina.

    Science.gov (United States)

    Hodžić, Adnan; Alić, Amer; Klebić, Ismar; Kadrić, Mirsad; Brianti, Emanuele; Duscher, Georg Gerhard

    2016-06-15

    Red fox (Vulpes vulpes) is considered as reservoir of different cardiorespiratory parasites of veterinary and medical importance. Since data on cardiorespiratory parasites in foxes in Bosnia and Herzegovina are still lacking, the aims of the present study were to (i) investigate the prevalence and geographical distribution of these parasites, (ii) determine genetic diversity of detected parasite species, and (iii) to estimate the role of foxes in the transmission cycle to companion animals and humans. Four species, morphologically and molecularly identified as Eucoleus boehmi (64.6%; 51/79), Eucoleus aerophilus (69.7%; 154/221), Crenosoma vulpis (45.7%; 101/221) and Linguatula serrata (1.3%; 1/79) were retrieved from nasal cavity and lungs in 184 (83.3%) animals. The occurrence of heartworms, Angiostrongylus vasorum and Dirofilaria immitis was not detected by necropsy or PCR. Furthermore, three distinct haplotypes of E. aerophilus (I, III, XV) and two of C. vulpis (I, II) previously reported in pet animals and wild carnivores were confirmed in this study. A new haplotype of C. vulpis (designated as haplotype V) was also identified based on 12S rRNA gene for the first time. The present study indicates a high prevalence and wide distribution of nasal and lung nematodes in fox population in Bosnia and Herzegovina, and supports the existence of transmission patterns between wildlife and pet animals. PMID:27198779

  10. Skeletal complications of eating disorders.

    Science.gov (United States)

    Donaldson, Abigail A; Gordon, Catherine M

    2015-09-01

    Anorexia nervosa (AN) is a psychiatric illness with profound medical consequences. Among the many adverse physical sequelae of AN, bone health is impacted by starvation and can be permanently impaired over the course of the illness. In this review of skeletal complications associated with eating disorders, we discuss the epidemiology, neuroendocrine changes, adolescent vs. adult skeletal considerations, orthopedic concerns, assessment of bone health, and treatment options for individuals with AN. The focus of the review is the skeletal sequelae associated with anorexia nervosa, but we also briefly consider other eating disorders that may afflict adolescents and young adults. The review presents updates to the field of bone health in AN, and also suggests knowledge gaps and areas for future investigation. PMID:26166318

  11. The outcomes of a 12-week Internet intervention aimed at improving fitness and health-related quality of life in overweight adolescents: the Young & Active controlled trial.

    Directory of Open Access Journals (Sweden)

    Kirsti Riiser

    Full Text Available Overweight and obesity among adolescents may have consequences, with potentially lasting effects on health and health-related quality of life (HRQoL. Excess weight is also associated with decreases in physical activity and cardiorespiratory fitness. The aim of the current study was to investigate the short-term effects of a 12-week Internet intervention in a primary care setting intended to increase cardiorespiratory fitness and HRQoL among overweight and obese adolescents.In this controlled trial, participants (13-15 years were non-randomly allocated to an intervention- or a control group. The intervention group received 12-weeks access to an online program providing tailored physical activity counseling based on principles from Self-determination Theory and Motivational Interviewing. The control group received standard follow-up by the school nurses. The primary outcome measure of cardiorespiratory fitness was determined using a shuttle run test. The secondary outcomes: HRQoL, leisure time exercise, body image and self-determined motivation for physical activity and exercise, were assessed by self-report measures. Age- and gender-adjusted body mass index (BMI was calculated based on measurements of height and weight. To compare pre-to post intervention differences within groups, a paired samples t-test was used while crude differences between groups were analyzed with an independent samples t-test.Of the 120 participants, 108 completed the study, 75 in the intervention group and 33 in the control group. Exposure to the intervention had a small effect on cardiorespiratory fitness (0.14; 95% CI [0.01;0.28]; P = 0.04, and a moderate effect on HRQoL (5.22; 95% CI [0.90; 9.53]; P = 0.02. Moreover, the control group increased significantly in BMI, yielding a moderate preventive effect on BMI (-0.39; 95% CI [-0.74;-0.03]; P = 0.03 for the intervention group.The results suggest that the Internet intervention with tailored physical activity counseling

  12. Cardiorespiratory Biomarker Responses in Healthy Young Adults to Drastic Air Quality Changes Surrounding the 2008 Beijing Olympics

    OpenAIRE

    Zhang, Junfeng; Zhu, Tong; Kipen, Howard; Wang, Guangfa; Huang, Wei; Rich, David; Zhu, Ping; Wang, Yuedan; Lu, Shou-En; Ohman-Strickland, Pamela; Diehl, Scott; Hu, Min; Tong, Jian; Gong, Jicheng; Thomas, Duncan

    2013-01-01

    Associations between air pollution and cardiorespiratory mortality and morbidity have been well established, but data to support biologic mechanisms underlying these associations are limited. We designed this study to examine several prominently hypothesized mechanisms by assessing Beijing residents’ biologic responses, at the biomarker level, to drastic changes in air quality brought about by unprecedented air pollution control measures implemented during the 2008 Beijing O...

  13. Fit 2-B FATHERS.

    Science.gov (United States)

    Maiorano, Joseph J.

    2001-01-01

    Fit 2-B FATHERS is a parenting-skills education program for incarcerated adult males. The goals of this program are for participants to have reduced recidivism rates and a reduced risk of their children acquiring criminal records. These goals are accomplished by helping participants become physically, practically, and socially fit for the demands…

  14. Fun Fitness Runs.

    Science.gov (United States)

    Scantling, Ed; Strand, Brad

    1997-01-01

    Fitness runs are planned activities that make running more interesting. The paper outlines five types of fitness runs, all of which can be modified to conform to different facilities, age groups, or available time. The activities have students playing detective, playing cards, deciphering words, learning about calories, and playing wolf. (SM)

  15. Fitness Test and Tips

    Institute of Scientific and Technical Information of China (English)

    Karen; Clark

    2005-01-01

    Summer is a time to exercise and keep fit.Ask yourself these quick questions and check your score below.How fit are you? 1.What is your pulse[脉搏]?Find your pulse in your wrist[手腕], count the number of beats[跳动] in one minute,Now

  16. Skeletal stem cells in space and time.

    Science.gov (United States)

    Kassem, Moustapha; Bianco, Paolo

    2015-01-15

    The nature, biological characteristics, and contribution to organ physiology of skeletal stem cells are not completely determined. Chan et al. and Worthley et al. demonstrate that a stem cell for skeletal tissues, and a system of more restricted, downstream progenitors, can be identified in mice and demonstrate its role in skeletal tissue maintenance and regeneration.

  17. Skeletal Muscle Hypertrophy after Aerobic Exercise Training

    OpenAIRE

    Konopka, Adam R.; Harber, Matthew P.

    2014-01-01

    Current dogma suggests aerobic exercise training has minimal effect on skeletal muscle size. We and others have demonstrated that aerobic exercise acutely and chronically alters protein metabolism and induces skeletal muscle hypertrophy. These findings promote an antithesis to the status quo by providing novel perspective on skeletal muscle mass regulation and insight into exercise-countermeasures for populations prone to muscle loss.

  18. Depressed GABA and glutamate synaptic signaling by 5-HT1A receptors in the nucleus tractus solitarii and their role in cardiorespiratory function

    OpenAIRE

    Ostrowski, Tim D.; Ostrowski, Daniela; Hasser, Eileen M.; Kline, David D.

    2014-01-01

    Serotonin (5-HT), and its 5-HT1A receptor (5-HT1AR) subtype, is a powerful modulator of the cardiorespiratory system and its sensory reflexes. The nucleus tractus solitarii (nTS) serves as the first central station for visceral afferent integration and is critical for cardiorespiratory reflex responses. However, the physiological and synaptic role of 5-HT1ARs in the nTS is relatively unknown. In the present study, we examined the distribution and modulation of 5-HT1ARs on cardiorespiratory an...

  19. Choosing a skeletal muscle relaxant.

    Science.gov (United States)

    See, Sharon; Ginzburg, Regina

    2008-08-01

    Skeletal muscle relaxants are widely used in treating musculoskeletal conditions. However, evidence of their effectiveness consists mainly of studies with poor methodologic design. In addition, these drugs have not been proven to be superior to acetaminophen or nonsteroidal anti-inflammatory drugs for low back pain. Systematic reviews and meta-analyses support using skeletal muscle relaxants for short-term relief of acute low back pain when nonsteroidal anti-inflammatory drugs or acetaminophen are not effective or tolerated. Comparison studies have not shown one skeletal muscle relaxant to be superior to another. Cyclobenzaprine is the most heavily studied and has been shown to be effective for various musculoskeletal conditions. The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms. Methocarbamol and metaxalone are less sedating, although effectiveness evidence is limited. Adverse effects, particularly dizziness and drowsiness, are consistently reported with all skeletal muscle relaxants. The potential adverse effects should be communicated clearly to the patient. Because of limited comparable effectiveness data, choice of agent should be based on side-effect profile, patient preference, abuse potential, and possible drug interactions. PMID:18711953

  20. Limitations of inclusive fitness.

    Science.gov (United States)

    Allen, Benjamin; Nowak, Martin A; Wilson, Edward O

    2013-12-10

    Until recently, inclusive fitness has been widely accepted as a general method to explain the evolution of social behavior. Affirming and expanding earlier criticism, we demonstrate that inclusive fitness is instead a limited concept, which exists only for a small subset of evolutionary processes. Inclusive fitness assumes that personal fitness is the sum of additive components caused by individual actions. This assumption does not hold for the majority of evolutionary processes or scenarios. To sidestep this limitation, inclusive fitness theorists have proposed a method using linear regression. On the basis of this method, it is claimed that inclusive fitness theory (i) predicts the direction of allele frequency changes, (ii) reveals the reasons for these changes, (iii) is as general as natural selection, and (iv) provides a universal design principle for evolution. In this paper we evaluate these claims, and show that all of them are unfounded. If the objective is to analyze whether mutations that modify social behavior are favored or opposed by natural selection, then no aspect of inclusive fitness theory is needed.

  1. Comparison between Variable and Conventional Volume-Controlled Ventilation on Cardiorespiratory Parameters in Experimental Emphysema

    Science.gov (United States)

    Henriques, Isabela; Padilha, Gisele A.; Huhle, Robert; Wierzchon, Caio; Miranda, Paulo J. B.; Ramos, Isalira P.; Rocha, Nazareth; Cruz, Fernanda F.; Santos, Raquel S.; de Oliveira, Milena V.; Souza, Sergio A.; Goldenberg, Regina C.; Luiz, Ronir R.; Pelosi, Paolo; de Abreu, Marcelo G.; Silva, Pedro L.; Rocco, Patricia R. M.

    2016-01-01

    Emphysema is characterized by loss of lung tissue elasticity and destruction of structures supporting alveoli and capillaries. The impact of mechanical ventilation strategies on ventilator-induced lung injury (VILI) in emphysema is poorly defined. New ventilator strategies should be developed to minimize VILI in emphysema. The present study was divided into two protocols: (1) characterization of an elastase-induced emphysema model in rats and identification of the time point of greatest cardiorespiratory impairment, defined as a high specific lung elastance associated with large right ventricular end-diastolic area; and (2) comparison between variable (VV) and conventional volume-controlled ventilation (VCV) on lung mechanics and morphometry, biological markers, and cardiac function at that time point. In the first protocol, Wistar rats (n = 62) received saline (SAL) or porcine pancreatic elastase (ELA) intratracheally once weekly for 4 weeks, respectively. Evaluations were performed 1, 3, 5, or 8 weeks after the last intratracheal instillation of saline or elastase. After identifying the time point of greatest cardiorespiratory impairment, an additional 32 Wistar rats were randomized into the SAL and ELA groups and then ventilated with VV or VCV (n = 8/group) [tidal volume (VT) = 6 mL/kg, positive end-expiratory pressure (PEEP) = 3 cmH2O, fraction of inspired oxygen (FiO2) = 0.4] for 2 h. VV was applied on a breath-to-breath basis as a sequence of randomly generated VT values (mean VT = 6 mL/kg), with a 30% coefficient of variation. Non-ventilated (NV) SAL and ELA animals were used for molecular biology analysis. The time point of greatest cardiorespiratory impairment, was observed 5 weeks after the last elastase instillation. At this time point, interleukin (IL)-6, cytokine-induced neutrophil chemoattractant (CINC)-1, amphiregulin, angiopoietin (Ang)-2, and vascular endothelial growth factor (VEGF) mRNA levels were higher in ELA compared to SAL. In ELA animals

  2. Comparison between Variable and Conventional Volume-Controlled Ventilation on Cardiorespiratory Parameters in Experimental Emphysema

    Science.gov (United States)

    Henriques, Isabela; Padilha, Gisele A.; Huhle, Robert; Wierzchon, Caio; Miranda, Paulo J. B.; Ramos, Isalira P.; Rocha, Nazareth; Cruz, Fernanda F.; Santos, Raquel S.; de Oliveira, Milena V.; Souza, Sergio A.; Goldenberg, Regina C.; Luiz, Ronir R.; Pelosi, Paolo; de Abreu, Marcelo G.; Silva, Pedro L.; Rocco, Patricia R. M.

    2016-01-01

    Emphysema is characterized by loss of lung tissue elasticity and destruction of structures supporting alveoli and capillaries. The impact of mechanical ventilation strategies on ventilator-induced lung injury (VILI) in emphysema is poorly defined. New ventilator strategies should be developed to minimize VILI in emphysema. The present study was divided into two protocols: (1) characterization of an elastase-induced emphysema model in rats and identification of the time point of greatest cardiorespiratory impairment, defined as a high specific lung elastance associated with large right ventricular end-diastolic area; and (2) comparison between variable (VV) and conventional volume-controlled ventilation (VCV) on lung mechanics and morphometry, biological markers, and cardiac function at that time point. In the first protocol, Wistar rats (n = 62) received saline (SAL) or porcine pancreatic elastase (ELA) intratracheally once weekly for 4 weeks, respectively. Evaluations were performed 1, 3, 5, or 8 weeks after the last intratracheal instillation of saline or elastase. After identifying the time point of greatest cardiorespiratory impairment, an additional 32 Wistar rats were randomized into the SAL and ELA groups and then ventilated with VV or VCV (n = 8/group) [tidal volume (VT) = 6 mL/kg, positive end-expiratory pressure (PEEP) = 3 cmH2O, fraction of inspired oxygen (FiO2) = 0.4] for 2 h. VV was applied on a breath-to-breath basis as a sequence of randomly generated VT values (mean VT = 6 mL/kg), with a 30% coefficient of variation. Non-ventilated (NV) SAL and ELA animals were used for molecular biology analysis. The time point of greatest cardiorespiratory impairment, was observed 5 weeks after the last elastase instillation. At this time point, interleukin (IL)-6, cytokine-induced neutrophil chemoattractant (CINC)-1, amphiregulin, angiopoietin (Ang)-2, and vascular endothelial growth factor (VEGF) mRNA levels were higher in ELA compared to SAL. In ELA animals

  3. Immediate Effects of Smoking on Cardiorespiratory Responses During Dynamic Exercise: Arm Versus Leg Ergometry

    Directory of Open Access Journals (Sweden)

    Chien-Liang eChen

    2015-12-01

    Full Text Available Purpose: This study compared the immediate effects of smoking on cardiorespiratory responses to dynamic arm and leg exercises. Methods: This randomized crossover study recruited 14 college students. Each participant underwent 2 sets of arm-cranking (AC and leg-cycling (LC exercise tests. The testing sequences of the control trial (participants refrained from smoking for 8 hours before testing and the experimental trial (participants smoked 2 cigarettes were randomly chosen. We observed immediate changes in pulmonary function and heart rate variability after smoking and before the exercise test. The participants then underwent graded exercise tests of their arms and legs, respectively, until reaching exhaustion. We compared the peak work achieved and the time to exhaustion during the exercise tests with various cardiorespiratory indices [i.e., heart rate, oxygen consumption (VO2, minute ventilation (VE]. The main effects of the time and the trial, as well as their interaction effects on outcome measures, were investigated using repeated measure ANOVA.Results: Five minutes after smoking, the participants exhibited reduced forced vital capacities and forced expiratory volumes in the first second (P < .05, in addition to elevated resting heart rates (P < .001. The high-frequency, low-frequency, and the total power of the heart rate variability were also reduced (P < .05 at rest. For the exercise test periods, smoking reduced the time to exhaustion (P = .005 and the ventilatory threshold (P < .05 in the LC tests, whereas there were no significant effects in the AC tests. A trend analysis revealed a significant (P < .001 trial-by-time interaction effect for heart rate, VO2, and VE during the graded exercise test. Lower VO2 and VE levels were exhibited in the exercise response of the smoking trial than in that of the control LC trials, whereas there was no discernable inter-trial difference in the AC trials. Moreover, the differences in heart rate

  4. Comparison between Variable and Conventional Volume-Controlled Ventilation on Cardiorespiratory Parameters in Experimental Emphysema.

    Science.gov (United States)

    Henriques, Isabela; Padilha, Gisele A; Huhle, Robert; Wierzchon, Caio; Miranda, Paulo J B; Ramos, Isalira P; Rocha, Nazareth; Cruz, Fernanda F; Santos, Raquel S; de Oliveira, Milena V; Souza, Sergio A; Goldenberg, Regina C; Luiz, Ronir R; Pelosi, Paolo; de Abreu, Marcelo G; Silva, Pedro L; Rocco, Patricia R M

    2016-01-01

    Emphysema is characterized by loss of lung tissue elasticity and destruction of structures supporting alveoli and capillaries. The impact of mechanical ventilation strategies on ventilator-induced lung injury (VILI) in emphysema is poorly defined. New ventilator strategies should be developed to minimize VILI in emphysema. The present study was divided into two protocols: (1) characterization of an elastase-induced emphysema model in rats and identification of the time point of greatest cardiorespiratory impairment, defined as a high specific lung elastance associated with large right ventricular end-diastolic area; and (2) comparison between variable (VV) and conventional volume-controlled ventilation (VCV) on lung mechanics and morphometry, biological markers, and cardiac function at that time point. In the first protocol, Wistar rats (n = 62) received saline (SAL) or porcine pancreatic elastase (ELA) intratracheally once weekly for 4 weeks, respectively. Evaluations were performed 1, 3, 5, or 8 weeks after the last intratracheal instillation of saline or elastase. After identifying the time point of greatest cardiorespiratory impairment, an additional 32 Wistar rats were randomized into the SAL and ELA groups and then ventilated with VV or VCV (n = 8/group) [tidal volume (VT) = 6 mL/kg, positive end-expiratory pressure (PEEP) = 3 cmH2O, fraction of inspired oxygen (FiO2) = 0.4] for 2 h. VV was applied on a breath-to-breath basis as a sequence of randomly generated VT values (mean VT = 6 mL/kg), with a 30% coefficient of variation. Non-ventilated (NV) SAL and ELA animals were used for molecular biology analysis. The time point of greatest cardiorespiratory impairment, was observed 5 weeks after the last elastase instillation. At this time point, interleukin (IL)-6, cytokine-induced neutrophil chemoattractant (CINC)-1, amphiregulin, angiopoietin (Ang)-2, and vascular endothelial growth factor (VEGF) mRNA levels were higher in ELA compared to SAL. In ELA animals

  5. Comparison between Variable and Conventional Volume-Controlled Ventilation on Cardiorespiratory Parameters in Experimental Emphysema.

    Science.gov (United States)

    Henriques, Isabela; Padilha, Gisele A; Huhle, Robert; Wierzchon, Caio; Miranda, Paulo J B; Ramos, Isalira P; Rocha, Nazareth; Cruz, Fernanda F; Santos, Raquel S; de Oliveira, Milena V; Souza, Sergio A; Goldenberg, Regina C; Luiz, Ronir R; Pelosi, Paolo; de Abreu, Marcelo G; Silva, Pedro L; Rocco, Patricia R M

    2016-01-01

    Emphysema is characterized by loss of lung tissue elasticity and destruction of structures supporting alveoli and capillaries. The impact of mechanical ventilation strategies on ventilator-induced lung injury (VILI) in emphysema is poorly defined. New ventilator strategies should be developed to minimize VILI in emphysema. The present study was divided into two protocols: (1) characterization of an elastase-induced emphysema model in rats and identification of the time point of greatest cardiorespiratory impairment, defined as a high specific lung elastance associated with large right ventricular end-diastolic area; and (2) comparison between variable (VV) and conventional volume-controlled ventilation (VCV) on lung mechanics and morphometry, biological markers, and cardiac function at that time point. In the first protocol, Wistar rats (n = 62) received saline (SAL) or porcine pancreatic elastase (ELA) intratracheally once weekly for 4 weeks, respectively. Evaluations were performed 1, 3, 5, or 8 weeks after the last intratracheal instillation of saline or elastase. After identifying the time point of greatest cardiorespiratory impairment, an additional 32 Wistar rats were randomized into the SAL and ELA groups and then ventilated with VV or VCV (n = 8/group) [tidal volume (VT) = 6 mL/kg, positive end-expiratory pressure (PEEP) = 3 cmH2O, fraction of inspired oxygen (FiO2) = 0.4] for 2 h. VV was applied on a breath-to-breath basis as a sequence of randomly generated VT values (mean VT = 6 mL/kg), with a 30% coefficient of variation. Non-ventilated (NV) SAL and ELA animals were used for molecular biology analysis. The time point of greatest cardiorespiratory impairment, was observed 5 weeks after the last elastase instillation. At this time point, interleukin (IL)-6, cytokine-induced neutrophil chemoattractant (CINC)-1, amphiregulin, angiopoietin (Ang)-2, and vascular endothelial growth factor (VEGF) mRNA levels were higher in ELA compared to SAL. In ELA animals

  6. Differences in Preseason Aerobic Fitness Screening in Professional and Pre-professional Modern Dancers.

    Science.gov (United States)

    Bronner, Shaw; Codman, Emma; Hash-Campbell, Dana; Ojofeitimi, Sheyi

    2016-03-01

    The aerobic demands of today's dance repertoire warrant understanding of the current cardiorespiratory fitness of dancers. The purpose of this study was to compare aerobic fitness levels of professional and pre-professional modern dancers and determine change over time. A retrospective analysis of four groups, two professional, and two pre-professional, was conducted in preseason annual screens, occurring before the professional dancers' rehearsal period and the students' academic training. Resting (HRrest), peak (HRpeak), and recovery (HRrecov) heart rate, and blood pressure (BP) were compared in 577 dancers, using an accelerated 3-minute step test. Smoking, asthma, and aerobic and cross training rates between groups were also compared. A 4 (group) X 2 (gender) MANOVA design determined differences between groups and genders in all dependent variables (p dance students over time. Additional aerobic training is recommended for pre-professional modern dance students to prepare them for the performance demands of a professional career. PMID:27025448

  7. The effect of physical fitness and physical exercise training on work productivity among health care workers

    DEFF Research Database (Denmark)

    Kongstad, Malte Bue; Christensen, Jeanette Reffstrup; Sjøgaard, Gisela;

    randomized controlled trial. WP was assessed as a summed score using selected, validated questions from three questionnaires (Health and Work Performance Questionnaire, Work Ability, and Quantity and Quality Method). Height and weight were measured to calculate BMI, CRF was measured using a bicycle ergometer......THE EFFECT OF PHYSICAL FITNESS AND PHYSICAL EXERCISE TRAINING ON WORK PRODUCTIVITY AMONG HEALTH CARE WORKERS Kongstad, M. 1, Sjøgaard, G. 1, Søgaard, K. 1, Christensen, JR. 1 1: SDU (Odense, Denmark) Introduction Workplace health promotion involving physical exercise training may negate lifestyle...... diseases and improve work productivity (WP) mediated by physiological variables such as BMI, cardiorespiratory fitness (CRF), and maximal voluntary contraction (MVC). The aim of this paper was to examine 1) the relationship between WP and the physiological variables BMI, CRF, and MVC in a cross...

  8. Exercise and Physical Fitness

    Science.gov (United States)

    ... Increase your chances of living longer Fitting regular exercise into your daily schedule may seem difficult at ... fine. The key is to find the right exercise for you. It should be fun and should ...

  9. Cardiorespiratory effects of outpatient anesthesia for oral surgery: trichloroethylene-halothane.

    Science.gov (United States)

    Allen, G D; Everett, G B; Haines, M

    1976-12-01

    The cardiorespiratory effects of trichloroethylene supplementation of nitrous oxide-oxygen anesthesia, with simultaneous use of halothane at induction as needed, were studied in outpatient oral surgery patients undergoing dental extractions under general anesthesia. The technique produced no deleterious cardiovascular effects that could be attributed to the combined use of these agents. Elevations of blood pressure, stroke volume, and peripheral resistance indicated light anesthesia. The versatility of halothane combined with the absence of nephrotoxic and hepatotoxic breakdown products of trichloroethylene provides a satisfactory technique for outpatient oral surgery. The agents appear pharmacologically complimentary in that halothane lacks analgesic properties and postoperative shivering occurs, while induction with trichloroethylene is slow and tachypnea is a problem. PMID:1069107

  10. Experimental evidence for phase synchronization transitions in human cardio-respiratory system

    CERN Document Server

    Bartsch, R; Kantelhardt, J W; Penzel, T; Bartsch, Ronny; Havlin, Shlomo; Kantelhardt, Jan W.; Penzel, Thomas

    2007-01-01

    Transitions in the dynamics of complex systems can be characterized by changes in the synchronization behavior of their components. Taking the human cardio-respiratory system as an example and using an automated procedure for screening the synchrograms of 112 healthy subjects we study the frequency and the distribution of synchronization episodes under different physiological conditions that occur during sleep. We find that phase synchronization between heartbeat and breathing is significantly enhanced during non-rapid-eye-movement (non-REM) sleep (deep sleep and light sleep) and reduced during REM sleep. Our results suggest that the synchronization is mainly due to a weak influence of the breathing oscillator upon the heartbeat oscillator, which is disturbed in the presence of long-term correlated noise, superimposed by the activity of higher brain regions during REM sleep.

  11. The universal Higgs fit

    OpenAIRE

    Pier Paolo Giardino; Kristjan Kannike(Scuola Normale Superiore and INFN, Piazza dei Cavalieri 7, 56126 Pisa, Italy); Isabella Masina(Dipartimento di Fisica e Scienze della Terra dell’Università di Ferrara and INFN, Italy); Martti Raidal; Alessandro Strumia(Dipartimento di Fisica, Università di Pisa and INFN, Italy)

    2014-01-01

    We perform a state-of-the-art global fit to all Higgs data. We synthesise them into a ‘universal’ form, which allows to easily test any desired model. We apply the proposed methodology to extract from data the Higgs branching ratios, production cross sections, couplings and to analyse composite Higgs models, models with extra Higgs doublets, supersymmetry, extra particles in the loops, anomalous top couplings, and invisible Higgs decays into Dark Matter. Best fit regions lie around the Standa...

  12. Fitting Galaxies on GPUs

    Science.gov (United States)

    Barsdell, B. R.; Barnes, D. G.; Fluke, C. J.

    2011-07-01

    Structural parameters are normally extracted from observed galaxies by fitting analytic light profiles to the observations. Obtaining accurate fits to high-resolution images is a computationally expensive task, requiring many model evaluations and convolutions with the imaging point spread function. While these algorithms contain high degrees of parallelism, current implementations do not exploit this property. With ever-growing volumes of observational data, an inability to make use of advances in computing power can act as a constraint on scientific outcomes. This is the motivation behind our work, which aims to implement the model-fitting procedure on a graphics processing unit (GPU). We begin by analysing the algorithms involved in model evaluation with respect to their suitability for modern many-core computing architectures like GPUs, finding them to be well-placed to take advantage of the high memory bandwidth offered by this hardware. Following our analysis, we briefly describe a preliminary implementation of the model fitting procedure using freely-available GPU libraries. Early results suggest a speed-up of around 10× over a CPU implementation. We discuss the opportunities such a speed-up could provide, including the ability to use more computationally expensive but better-performing fitting routines to increase the quality and robustness of fits.

  13. Effects of eight-week supplementation of Ashwagandha on cardiorespiratory endurance in elite Indian cyclists

    Directory of Open Access Journals (Sweden)

    Shweta Shenoy

    2012-01-01

    Full Text Available Background: Cycling is an endurance sport relying mainly on aerobic capacity to provide fuel during long-duration cycling events. Athletes are constantly searching for new methods to improve this capacity through various nutritional and ergogenic aids. Purpose: The aim of the study was to find out the effect of Ashwagandha on the cardiorespiratory endurance capacity, that is, aerobic capacity of elite Indian cyclists. Materials and Methods: Forty elite (elite here refers to the participation of the athlete in at least state-level events Indian cyclists were chosen randomly and were equally divided into experimental and placebo groups. The experimental group received 500 mg capsules of aqueous roots of Ashwagandha twice daily for eight weeks, whereas the placebo group received starch capsules. Outcome Measures: The baseline treadmill test for the cyclists were performed to measure their aerobic capacity in terms of maximal aerobic capacity (VO 2 max, metabolic equivalent, respiratory exchange ratio (RER, and total time for the athlete to reach his exhaustion stage. After eight weeks of supplementation, the treadmill test was again performed and results were obtained. Results: There was significant improvement in the experimental group in all parameters, whereas the placebo group did not show any change with respect to their baseline parameters. There was significant improvement in the experimental group in all parameters, namely, VO 2 max (t = 5.356; P < 0.001, METS (t = 4.483; P < 0.001, and time for exhaustion on treadmill (t = 4.813; P < 0.001 in comparison to the placebo group which did not show any change with respect to their baseline parameters. Conclusion: Ashwagandha improved the cardiorespiratory endurance of the elite athletes.

  14. PM2.5, oxidant defence and cardiorespiratory health: a review.

    Science.gov (United States)

    Weichenthal, Scott A; Godri-Pollitt, Krystal; Villeneuve, Paul J

    2013-05-04

    Airborne fine particle mass concentrations (PM2.5) are used for ambient air quality management worldwide based in part on known cardiorespiratory health effects. While oxidative stress is generally thought to be an important mechanism in determining these effects, relatively few studies have specifically examined how oxidant defence may impact susceptibility to particulate air pollution. Here we review studies that explore the impact of polymorphisms in anti-oxidant related genes or anti-oxidant supplementation on PM2.5-induced cardiorespiratory outcomes in an effort to summarize existing evidence related to oxidative stress defence and the health effects of PM2.5. Recent studies of PM-oxidative burden were also examined. In total, nine studies were identified and reviewed and existing evidence generally suggests that oxidant defence may modify the impact of PM2.5 exposure on various health outcomes, particularly heart rate variability (a measure of autonomic function) which was the most common outcome examined in the studies reviewed. Few studies examined interactions between PM2.5 and oxidant defence for respiratory outcomes, and in general studies focused primarily on acute health effects. Therefore, further evaluation of the potential modifying role of oxidant defence in PM2.5-induced health effects is required, particularly for chronic outcomes. Similarly, while an exposure metric that captures the ability of PM2.5 to cause oxidative stress may offer advantages over traditional mass concentration measurements, little epidemiological evidence is currently available to evaluate the potential benefits of such an approach. Therefore, further evaluation is required to determine how this metric may be incorporated in ambient air quality management.

  15. Slow breathing and hypoxic challenge: cardiorespiratory consequences and their central neural substrates.

    Directory of Open Access Journals (Sweden)

    Hugo D Critchley

    Full Text Available Controlled slow breathing (at 6/min, a rate frequently adopted during yoga practice can benefit cardiovascular function, including responses to hypoxia. We tested the neural substrates of cardiorespiratory control in humans during volitional controlled breathing and hypoxic challenge using functional magnetic resonance imaging (fMRI. Twenty healthy volunteers were scanned during paced (slow and normal rate breathing and during spontaneous breathing of normoxic and hypoxic (13% inspired O2 air. Cardiovascular and respiratory measures were acquired concurrently, including beat-to-beat blood pressure from a subset of participants (N = 7. Slow breathing was associated with increased tidal ventilatory volume. Induced hypoxia raised heart rate and suppressed heart rate variability. Within the brain, slow breathing activated dorsal pons, periaqueductal grey matter, cerebellum, hypothalamus, thalamus and lateral and anterior insular cortices. Blocks of hypoxia activated mid pons, bilateral amygdalae, anterior insular and occipitotemporal cortices. Interaction between slow breathing and hypoxia was expressed in ventral striatal and frontal polar activity. Across conditions, within brainstem, dorsal medullary and pontine activity correlated with tidal volume and inversely with heart rate. Activity in rostroventral medulla correlated with beat-to-beat blood pressure and heart rate variability. Widespread insula and striatal activity tracked decreases in heart rate, while subregions of insular cortex correlated with momentary increases in tidal volume. Our findings define slow breathing effects on central and cardiovascular responses to hypoxic challenge. They highlight the recruitment of discrete brainstem nuclei to cardiorespiratory control, and the engagement of corticostriatal circuitry in support of physiological responses that accompany breathing regulation during hypoxic challenge.

  16. Association between swimming performance, cardiorespiratory morphometry and thermal tolerance in Atlantic salmon (Salmo salar L.

    Directory of Open Access Journals (Sweden)

    Katja eAnttila

    2014-12-01

    Full Text Available This experiment tested the hypothesis that swimming performance in Atlantic salmon (Salmo salar parr is connected to cardiorespiratory performance and morphology, as well as maximum heart rate (fHmax related measures of thermal tolerance. Moreover, it was hypothesized that the cardiorespiratory differences between poor and strong swimmers will be retained in a later life stage, i.e., 15 weeks post-smoltification and seawater transfer. This experiment screened a population of 3,200 parr (11.2 ± 0.25 g for their swimming performance, classifying them as poor and good swimmers based on their critical swimming speeds (4.4±0.1 body length s-1 and >6.8±0.1 body length s-1, respectively. Compared with poor performing parr, good swimmers had a significantly thicker compact myocardium (by 23.7% and taller gill secondary lamellae (by 16.2%. In contrast, there was no significant difference in maximum oxygen consumption between the two groups as assessed using a ‘chase’ protocol, and the relationship between heart rate specific measures of thermal tolerance and swim performance was variable. For example, three measures did not differ between the two groups, whereas the Arrhenius breakpoint temperature for fHmax and fHmax were higher and lower, respectively, in the poor swimmers. Importantly, the identified morphological and fHmax differences at the parr stage persisted after 15 weeks of common garden rearing in seawater, and they were associated with an increase in relative ventricular mass and a small, but significant, improvement in growth rate. Therefore, it seems that an early assessment of swimming performance can effectively screen for morphological capacities related to oxygen supply and growth rate, but less so for heart rate related measures of thermal tolerance.

  17. Cardio-respiratory and electromyographic responses to ergometer and on-water rowing in elite rowers.

    Science.gov (United States)

    Bazzucchi, I; Sbriccoli, P; Nicolò, A; Passerini, A; Quinzi, F; Felici, F; Sacchetti, M

    2013-05-01

    The aim of this study was to compare muscle activation and cardio-respiratory response during ergometer and on-water rowing. Nine internationally competitive rowers (five Olympic Games medal winners, age 25.6 ± 4.8 years) were requested to perform a 1,000 m race simulation test in the two conditions. Surface electromyographic (sEMG) signals from trapezius superior (TRS), latissimus dorsi (LD), biceps brachii (BB), rectus femoris (RF), vastus medialis (VAM), vastus lateralis (VAL), biceps femoris (BF) and tibialis anterior (TA) muscles were recorded continuously during the tests together with other cardio-respiratory parameters: heart rate (HR), ventilation (VE), oxygen consumption (VO₂). On-water, subjects covered the same distance in a longer time (218.4 ± 3.8 s vs. 178.1 ± 5.6 s during ergometer test). TRS, LD, BB, RF, VAM and VAL muscle activation on-water was lower than off-water during the rowing race. VO₂ and VE responses were similar between the two conditions even if the time to complete the 1,000 m race simulation test was higher on-water. The results indicate that for most of the analyzed muscles EMG activation on the ergometer is higher than on-water with the maximal activity at the beginning of the on-water test due reasonably to overcome the forces opposing the forward motion, while the ergometer task elicited increasing muscle activation over time. The present data may be considered by coaches when choosing a rowing ergometer in substitution for the training on-water or when relying on the indoor tests to select the crew. PMID:23179206

  18. Cardiorespiratory and metabolic alterations during exercise and passive recovery after three modes of exercise.

    Science.gov (United States)

    Mandroukas, Athanasios; Heller, Jan; Metaxas, Thomas I; Sendelides, Thomas; Riganas, Cheistos; Vamvakoudis, Efstratios; Christoulas, Kosmas; Stefanidis, Panagiotis; Karagiannis, Vasilis; Kyparos, Antonios; Mandroukas, Konstantinos

    2011-06-01

    The objective of this study was to investigate the potential variations in cardiorespiratory and metabolic parameters and running performance among 3 modes of exercise of the same duration, namely, intermittent running with active recovery (AR) or passive recovery (PR) and continuous running (CR) and whether these variations could affect passive recovery time (PRT). Fifteen male physical education students with a subspecialty in soccer were studied (mean age 22.3 ± 2.5 years, training experience 12.3 ± 2.5 years) in the middle of the playing season. The results showed that during exercise, the highest heart rate (HR) and VO2 values were observed in CR, whereas the lowest values in PR followed by AR. Blood lactate (BLa) concentration was higher in PR by 38% compared to that in AR (p < 0.05). The exercise duration was similar between PR and AR tests and longer than in CR. With regard to PRT, the highest HR (186 ± 9 b · min(-1)), VO2 (55.5 ± 5.2 ml · kg(-1) · min(-1)), and BLa (5.1 ± 1.7 mmol · L(-1)) values were found in CR. No differences in HR and VO2 between PR and AR were detected. However, despite the differences in BLa concentration between AR and PR during exercise, the PRT BLa values between these 2 exercise modes were not different. Among the 3 running protocols, only CR appeared to have fully challenged the cardiorespiratory system inducing maximal HR and VO2 responses during exercise and high BLa values in PRT, yet these responses were not associated with better exercise performance compared to intermittent running. Therefore, intermittent exercise, regardless of implementing passive or active interval, might be the preferable exercise mode particularly in activities extended over 30 minutes. PMID:21273910

  19. Cardio-respiratory effects of systemic neurotensin injection are mediated through activation of neurotensin NTS₁ receptors.

    Science.gov (United States)

    Kaczyńska, Katarzyna; Szereda-Przestaszewska, Małgorzata

    2012-09-15

    The purpose of our study was to determine the cardio-respiratory pattern exerted by the systemic injection of neurotensin, contribution of neurotensin NTS(1) receptors and the neural pathways mediating the responses. The effects of an intravenous injection (i.v.) of neurotensin were investigated in anaesthetized, spontaneously breathing rats in following experimental schemes: (i) control animals before and after midcervical vagotomy; (ii) in three separate subgroups of rats: neurally intact, vagotomized at supranodosal level and initially midcervically vagotomized exposed to section of the carotid sinus nerves (CSNs); (iii) in the intact rats 2 minutes after blockade of neurotensin NTS(1) receptors with SR 142948. Intravenous injection of 10 μg/kg of neurotensin in the intact rats evoked prompt increase in the respiratory rate followed by a prolonged slowing down coupled with augmented tidal volume. Midcervical vagotomy precluded the effects of neurotensin on the frequency of breathing, while CSNs section reduced the increase in tidal volume. In all the neural states neurotensin caused significant fall in mean arterial blood pressure preceded by prompt hypertensive response. The cardio-respiratory effects of neurotensin were blocked by pre-treatment with NTS(1) receptor antagonist. The results of this study showed that neurotensin acting through NTS(1) receptors augments the tidal component of the breathing pattern in a large portion via carotid body afferentation whereas the respiratory timing response to neurotensin depends entirely on the intact midcervical vagi. Blood pressure effects evoked by an intravenous neurotensin occur outside vagal and CSNs pathways and might result from activation of the peripheral vascular NTS(1) receptors.

  20. Design of the Physical exercise during Adjuvant Chemotherapy Effectiveness Study (PACES):A randomized controlled trial to evaluate effectiveness and cost-effectiveness of physical exercise in improving physical fitness and reducing fatigue

    OpenAIRE

    Sonke Gabe S; van Harten Wim H; Stuiver Martijn M; van Waart Hanna; Aaronson Neil K

    2010-01-01

    Abstract Background Cancer chemotherapy is frequently associated with a decline in general physical condition, exercise tolerance, and muscle strength and with an increase in fatigue. While accumulating evidence suggests that physical activity and exercise interventions during chemotherapy treatment may contribute to maintaining cardiorespiratory fitness and strength, the results of studies conducted to date have not been consistent. Additional research is needed to determine the optimal inte...

  1. Skeletal Maturation and Aerobic Performance in Young Soccer Players from Professional Academies.

    Science.gov (United States)

    Teixeira, A S; Valente-dos-Santos, J; Coelho-E-Silva, M J; Malina, R M; Fernandes-da-Silva, J; Cesar do Nascimento Salvador, P; De Lucas, R D; Wayhs, M C; Guglielmo, L G A

    2015-11-01

    The contribution of chronological age, skeletal age (Fels method) and body size to variance in peak velocity derived from the Carminatti Test was examined in 3 competitive age groups of Brazilian male soccer players: 10-11 years (U-12, n=15), 12-13 years (U-14, n=54) and 14-15 years (U-16, n=23). Body size and soccer-specific aerobic fitness were measured. Body composition was predicted from skinfolds. Analysis of variance and covariance (controlling for chronological age) were used to compare soccer players by age group and by skeletal maturity status within of each age group, respectively. Relative skeletal age (skeletal age minus chronological age), body size, estimated fat-free mass and performance on the Carminatti Test increased significantly with age. Carminatti Test performance did not differ among players of contrasting skeletal maturity status in the 3 age groups. Results of multiple linear regressions indicated fat mass (negative) and chronological age (positive) were significant predictors of peak velocity derived from the Carminatti Test, whereas skeletal age was not a significant predictor. In conclusion, the Carminatti Test appears to be a potentially interesting field protocol to assess intermittent endurance running capacity in youth soccer programs since it is independent of biological maturity status. PMID:26258825

  2. Metabolic rate and cardiorespiratory response during hybrid cycling versus handcycling at equal subjective exercise intensity levels in people with spinal cord injury

    NARCIS (Netherlands)

    Bakkum, Arjan J. T.; de Groot, Sonja; Onderwater, Mark Q.; de Jong, Jelle; Janssen, Thomas W. J.

    2014-01-01

    Objective: To compare the metabolic rate and cardiorespiratory response during hybrid cycling versus handcycling at equal subjective exercise intensity levels in people with spinal cord injury (SCI). Design: Cross-sectional study. Setting: Amsterdam Rehabilitation Research Centre vertical bar Reade,

  3. Extensive fitness and human cooperation

    OpenAIRE

    van Hateren, J.H.

    2015-01-01

    Evolution depends on the fitness of organisms, the expected rate of reproducing. Directly getting offspring is the most basic form of fitness, but fitness can also be increased indirectly by helping genetically related individuals (such as kin) to increase their fitness. The combined effect is known as inclusive fitness. Here it is argued that a further elaboration of fitness has evolved, particularly in humans. It is called extensive fitness and it incorporates producing organisms that are m...

  4. Media device ownership and media use: Associations with sedentary time, physical activity and fitness in English youth.

    Science.gov (United States)

    Sandercock, Gavin R H; Alibrahim, Mohammed; Bellamy, Mark

    2016-12-01

    The aim of this study was to determine whether ownership and use of electronic media were associated with sedentary time and cardiorespiratory fitness (fitness) in youth. We also aimed to determine if associations were independent of physical activity (PA). Fitness was measured using the 20 m shuttle-run. PA, sedentary time, ownership of media devices and media use were self-reported. Participants (n = 678, age 10-15 years) reported daily sedentary time of 620 (± 210) min. Forty-one percent of participants had low PA and 50.4% had low fitness. Higher weekend sedentary time was associated with low fitness in girls (p = 0.005) and boys (p digital/satellite TV receivers (OR = 1.8, 95%CI: 1.8-3.2). Schoolchildren spent > 10 h or ~ 85% of each waking day sedentary. Use of social media was associated with higher sedentary time in both sexes and with low fitness in girls. Reducing social media use in youth offers one potential target for intervention. Behaviours associated with sedentary time differed from predictors of low fitness. The complex and often sex-specific interactions identified between sedentary time, PA and fitness suggest the need for carefully targeted interventions to reduce sedentary time and improve fitness in English youth. PMID:27413678

  5. Skeletal fluorosis in immobilized extremities.

    Science.gov (United States)

    Rosenquist, J B

    1975-11-01

    The effect of immobilization on skeletal fluorosis was studied in growing rabbits. One hind leg was immobilized by an external fixation device extending below the wrist joint and above the knee joint, the extremity being in a straight position after severance of the sciatic nerve. The animals, aged 7 weeks at the beginning of the experiment, were given 10 mg of fluoride per kg body weight and day during 12 weeks. In the tibiae, development of the skeletal fluorosis was more irregular than that observed in previous studies of normally active animals, being most excessive in the mobile bone. The immobilization effect was most profound in the femora as the cortical thickness and the femur score were significantly higher than those in the mobile femora. It was suggested that an altered muscular activity was the reason for the observed changes. PMID:1189918

  6. Skeletal and body composition evaluation

    Science.gov (United States)

    Mazess, R. B.

    1983-01-01

    Research on radiation detectors for absorptiometry; analysis of errors affective single photon absorptiometry and development of instrumentation; analysis of errors affecting dual photon absorptiometry and development of instrumentation; comparison of skeletal measurements with other techniques; cooperation with NASA projects for skeletal evaluation in spaceflight (Experiment MO-78) and in laboratory studies with immobilized animals; studies of postmenopausal osteoporosis; organization of scientific meetings and workshops on absorptiometric measurement; and development of instrumentation for measurement of fluid shifts in the human body were performed. Instrumentation was developed that allows accurate and precise (2% error) measurements of mineral content in compact and trabecular bone and of the total skeleton. Instrumentation was also developed to measure fluid shifts in the extremities. Radiation exposure with those procedures is low (2-10 MREM). One hundred seventy three technical reports and one hundred and four published papers of studies from the University of Wisconsin Bone Mineral Lab are listed.

  7. Skeletal Fragility in Endogenous Hypercortisolism.

    Science.gov (United States)

    Mazziotti, Gherardo; Delgado, Adriano; Maffezzoni, Filippo; Formenti, Annamaria; Giustina, Andrea

    2016-01-01

    Skeletal fragility is a frequent complication of endogenous hypercortisolism, and fragility fractures may be the first clinical manifestation of the disease. Fractures involve more frequently the vertebrae and may occur in 30-50% of the patients exposed to glucocorticoid excess, in close relationship with severity and duration of hypercortisolism. Although improvement of bone mineral density was reported after resolution of hypercortisolism, there are patients with persistently high fracture risk after the cure of hypercortisolism, and other patients in whom the resolution of hypercortisolism may take a long time, implying a multistep therapeutic approach. Since vertebral fractures tend to occur early during the natural history of disease, a skeletal-specific approach should be undertaken in these patients; however, the cost-effectiveness of this approach is still largely unknown since data on effectiveness and safety of bone-active drugs in endogenous hypercortisolism are scarce. PMID:27210111

  8. Optimization of inclusive fitness.

    Science.gov (United States)

    Grafen, Alan

    2006-02-01

    The first fully explicit argument is given that broadly supports a widespread belief among whole-organism biologists that natural selection tends to lead to organisms acting as if maximizing their inclusive fitness. The use of optimization programs permits a clear statement of what this belief should be understood to mean, in contradistinction to the common mathematical presumption that it should be formalized as some kind of Lyapunov or even potential function. The argument reveals new details and uncovers latent assumptions. A very general genetic architecture is allowed, and there is arbitrary uncertainty. However, frequency dependence of fitnesses is not permitted. The logic of inclusive fitness immediately draws together various kinds of intra-genomic conflict, and the concept of 'p-family' is introduced. Inclusive fitness is thus incorporated into the formal Darwinism project, which aims to link the mathematics of motion (difference and differential equations) used to describe gene frequency trajectories with the mathematics of optimization used to describe purpose and design. Important questions remain to be answered in the fundamental theory of inclusive fitness. PMID:16046225

  9. Skeletal muscle: an endocrine organ.

    Science.gov (United States)

    Pratesi, Alessandra; Tarantini, Francesca; Di Bari, Mauro

    2013-01-01

    Tropism and efficiency of skeletal muscle depend on the complex balance between anabolic and catabolic factors. This balance gradually deteriorates with aging, leading to an age-related decline in muscle quantity and quality, called sarcopenia: this condition plays a central role in physical and functional impairment in late life. The knowledge of the mechanisms that induce sarcopenia and the ability to prevent or counteract them, therefore, can greatly contribute to the prevention of disability and probably also mortality in the elderly. It is well known that skeletal muscle is the target of numerous hormones, but only in recent years studies have shown a role of skeletal muscle as a secretory organ of cytokines and other peptides, denominated myokines (IL6, IL8, IL15, Brain-derived neurotrophic factor, and leukaemia inhibitory factor), which have autocrine, paracrine, or endocrine actions and are deeply involved in inflammatory processes. Physical inactivity promotes an unbalance between these substances towards a pro-inflammatory status, thus favoring the vicious circle of sarcopenia, accumulation of fat - especially visceral - and development of cardiovascular diseases, type 2 diabetes mellitus, cancer, dementia and depression, according to what has been called "the diseasome of physical inactivity". PMID:23858303

  10. Alternative Astronomical FITS imaging

    CERN Document Server

    Varsaki, Eleni E; Fotopoulos, Vassilis; Skodras, Athanassios N

    2012-01-01

    Astronomical radio maps are presented mainly in FITS format. Astronomical Image Processing Software (AIPS) uses a set of tables attached to the output map to include all sorts of information concerning the production of the image. However this information together with information on the flux and noise of the map is lost as soon as the image of the radio source in fits or other format is extracted from AIPS. This information would have been valuable to another astronomer who just uses NED, for example, to download the map. In the current work, we show a method of data hiding inside the radio map, which can be preserved under transformations, even for example while the format of the map is changed from fits to other lossless available image formats.

  11. Fitting Galaxies on GPUs

    CERN Document Server

    Barsdell, Benjamin R; Fluke, Christopher J

    2011-01-01

    Structural parameters are normally extracted from observed galaxies by fitting analytic light profiles to the observations. Obtaining accurate fits to high-resolution images is a computationally expensive task, requiring many model evaluations and convolutions with the imaging point spread function. While these algorithms contain high degrees of parallelism, current implementations do not exploit this property. With evergrowing volumes of observational data, an inability to make use of advances in computing power can act as a constraint on scientific outcomes. This is the motivation behind our work, which aims to implement the model-fitting procedure on a graphics processing unit (GPU). We begin by analysing the algorithms involved in model evaluation with respect to their suitability for modern many-core computing architectures like GPUs, finding them to be well-placed to take advantage of the high memory bandwidth offered by this hardware. Following our analysis, we briefly describe a preliminary implementa...

  12. Skeletal muscle microvascular function in girls with Turner syndrome

    Science.gov (United States)

    West, Sarah L.; O'Gorman, Clodagh S.; Elzibak, Alyaa H.; Caterini, Jessica; Noseworthy, Michael D.; Rayner, Tammy; Hamilton, Jill; Wells, Greg D.

    2014-01-01

    Background Exercise intolerance is prevalent in individuals with Turner Syndrome (TS). We recently demonstrated that girls with TS have normal aerobic but altered skeletal muscle anaerobic metabolism compared to healthy controls (HC). The purpose of this study was to compare peripheral skeletal muscle microvascular function in girls with TS to HC after exercise. We hypothesized that girls with TS would have similar muscle blood-oxygen level-dependent (BOLD) magnetic resonance imaging (MRI) signal responses during recovery from exercise compared to HC. Methods Thirteen TS participants and 8 HC completed testing. BOLD MRI was used to measure skeletal muscle microvascular response during 60 second recovery, following 60 s of exercise at 65% of maximal workload. Exercise and recovery were repeated four times, and the BOLD signal time course was fit to a four-parameter sigmoid function. Results Participants were 13.7 ± 3.1 years old and weighed 47.9 ± 14.6 kg. The mean change in BOLD signal intensity following exercise at the end of recovery, the mean response time of the function/the washout of deoxyhemoglobin, and the mean half-time of recovery were similar between the TS and HC groups. Conclusions Our results demonstrate that compared to HC, peripheral skeletal muscle microvascular function following exercise in girls with TS is not impaired. General significance This study supports the idea that the aerobic energy pathway is not impaired in children with TS in response to submaximal exercise. Other mechanisms are likely responsible for exercise intolerance in TS; this needs to be further investigated. PMID:26676172

  13. Suspected motor problems and low preference for active play in childhood are associated with physical inactivity and low fitness in adolescence.

    Directory of Open Access Journals (Sweden)

    Marko T Kantomaa

    Full Text Available BACKGROUND: This prospective longitudinal study investigates whether suspected motor problems and low preference for active play in childhood are associated with physical inactivity and low cardiorespiratory fitness in adolescence. METHODOLOGY/PRINCIPAL FINDINGS: The study sample consisted of the Northern Finland Birth Cohort 1986 (NFBC 1986 composed of 5,767 children whose parents responded to a postal inquiry concerning their children's motor skills at age 8 years and who themselves reported their physical activity at age 16 years. Cardiorespiratory fitness was measured with a cycle ergometer test at age 16 years. Odds ratios (OR and their 95% confidence intervals (95% CI for the level of physical activity and fitness were obtained from multinomial logistic regression and adjusted for socio-economic position and body mass index. Low preference for active play in childhood was associated with physical inactivity (boys: OR 3.31, 95% CI 2.42-4.53; girls: OR 1.79, 95% CI 1.36-2.36 and low cardiorespiratory fitness (boys: OR 1.87, 95% CI 1.27-2.74; girls: OR 1.52, 95% CI 1.09-2.11 in adolescence. Suspected gross (OR 2.16, 95% CI 1.33-3.49 and fine (OR 1.88, 95% CI 1.35-2.60 motor problems were associated with physical inactivity among boys. Children with suspected motor problems and low preference for active play tended to have an even higher risk of physical inactivity in adolescence. CONCLUSIONS/SIGNIFICANCE: Low preference for active play in childhood was associated with physical inactivity and low cardiorespiratory fitness in adolescence. Furthermore, children with suspected motor problems and low preference for active play tended to have an even higher risk of physical inactivity in adolescence. Identification of children who do not prefer active play and who have motor problems may allow targeted interventions to support their motor learning and participation in active play and thereby promote their physical activity and fitness in later life.

  14. Increased skeletal muscle capillarization enhances insulin sensitivity

    DEFF Research Database (Denmark)

    Åkerström, Thorbjörn; Laub, Lasse; Vedel, Kenneth;

    2014-01-01

    Increased skeletal muscle capillarization is associated with improved glucose tolerance and insulin sensitivity. However, a possible causal relationship has not previously been identified. We therefore investigated whether increased skeletal muscle capillarization increases insulin sensitivity......-body insulin sensitivity increased by ~24% and insulin-stimulated skeletal muscle 2-deoxy-[(3)H]-Glucose disposal increased by ~30% concomitant with a ~20% increase in skeletal muscle capillarization. Adipose tissue insulin sensitivity was not affected by the treatment. Insulin-stimulated muscle glucose uptake...... the rats on any other parameters measured. We conclude that an increase in skeletal muscle capillarization is associated with increased insulin sensitivity. These data point towards the importance of increasing skeletal muscle capillarization for prevention or treatment of type 2 diabetes....

  15. The exercised skeletal muscle: a review

    Directory of Open Access Journals (Sweden)

    Marina Marini

    2010-09-01

    Full Text Available The skeletal muscle is the second more plastic tissue of the body - second to the nervous tissue only. In fact, both physical activity and inactivity contribute to modify the skeletal muscle, by continuous signaling through nerve impulses, mechanical stimuli and humoral clues. In turn, the skeletal muscle sends signals to the body, thus contributing to its homeostasis. We'll review here the contribute of physical exercise to the shaping of skeletal muscle, to the adaptation of its mass and function to the different needs imposed by different physical activities and to the attainment of the health benefits associated with active skeletal muscles. Focus will primarily be on the molecular pathways and on gene regulation that result in skeletal muscle adaptation to exercise.

  16. Linking the Fits, Fitting the Links: Connecting Different Types of PO Fit to Attitudinal Outcomes

    Science.gov (United States)

    Leung, Aegean; Chaturvedi, Sankalp

    2011-01-01

    In this paper we explore the linkages among various types of person-organization (PO) fit and their effects on employee attitudinal outcomes. We propose and test a conceptual model which links various types of fits--objective fit, perceived fit and subjective fit--in a hierarchical order of cognitive information processing and relate them to…

  17. Advances and challenges in skeletal muscle angiogenesis

    DEFF Research Database (Denmark)

    Olfert, I Mark; Baum, Oliver; Hellsten, Ylva;

    2016-01-01

    during health, but poorly controlled in disease - resulting in either excessive capillary growth (pathological angiogenesis) or losses in capillarity (rarefaction). Given that skeletal muscle comprises nearly 40% of body mass in humans, skeletal muscle capillary density has a significant impact...... on 1) the methodological concerns that have arisen in determining skeletal muscle capillarity, and 2) highlight the concepts that are reshaping our understanding of the angio-adaptation process. We also summarize selected new findings (physical influences, molecular changes and ultrastructural...

  18. Cerebellar medulloblastoma presenting with skeletal metastasis

    OpenAIRE

    Barai Sukanta; Bandopadhayaya G; Julka P; Dhanapathi H; Haloi A; Seith A

    2004-01-01

    Medulloblastomas are highly malignant brain tumours, but only rarely produce skeletal metastases. No case of medulloblastoma has been documented to have produced skeletal metastases prior to craniotomy or shunt surgery. A 21-year-old male presented with pain in the hip and lower back with difficulty in walking of 3 months′ duration. Signs of cerebellar dysfunction were present hence a diagnosis of cerebellar neoplasm or skeletal tuberculosis with cerebellar abscess formation was consid...

  19. Nutrient and energy sensing in skeletal muscle

    OpenAIRE

    Deshmukh, Atul S.

    2009-01-01

    Nutrient overload and physical inactivity often leads to the development of obesity and type 2 diabetes. Acute over-nutrition can induce insulin resistance, while physical exercise enhances skeletal muscle insulin sensitivity. Like every living cell, skeletal muscle senses nutrient and energy signals and to adjust metabolic flux. This thesis focuses on some of the key nutrient and energy sensing (exercise/contraction-induced) pathways in skeletal muscle that regulate metabol...

  20. The Effects of Lactate on Skeletal Muscle

    OpenAIRE

    Willkomm, Lena

    2014-01-01

    Regular exercise and physical activity are cornerstones in the prevention and treatment of numerous chronic conditions, such as type 2 diabetes, coronary heart disease, and age-related sarcopenia. The associated health benefits arise from a number of tissues but due to its high plasticity skeletal muscle plays a pivotal role. The resident stem cells of skeletal muscle tissue, so called Satellite cells (SCs), contribute significantly to skeletal muscle adaptation and hence, maintenance of heal...

  1. Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory homeostatic nuclei

    OpenAIRE

    Freeman Kate; Brureau Anthony; Vadigepalli Rajanikanth; Staehle Mary M; Brureau Melanie M; Gonye Gregory E; Hoek Jan B; Hooper D; Schwaber James S

    2012-01-01

    Abstract Background Chronic alcohol use changes the brain’s inflammatory state. However, there is little work examining the progression of the cytokine response during alcohol withdrawal, a period of profound autonomic and emotional upset. This study examines the inflammatory response in the central nucleus of the amygdala (CeA) and dorsal vagal complex (DVC), brain regions neuroanatomically associated with affective and cardiorespiratory regulation in an in vivo rat model of withdrawal follo...

  2. The role of particulate size and chemistry in the association between summertime ambient air pollution and hospitalization for cardiorespiratory diseases.

    OpenAIRE

    Burnett, R.T.; Cakmak, S; Brook, J. R.; Krewski, D

    1997-01-01

    In order to address the role that the ambient air pollution mix, comprised of gaseous pollutants and various physical and chemical measures of particulate matter, plays in exacerbating cardiorespiratory disease, daily measures of fine and coarse particulate mass, aerosol chemistry (sulfates and acidity), and gaseous pollution (ozone, nitrogen dioxide, sulfur dioxide, and carbon monoxide) were collected in Toronto, Ontario, Canada, in the summers of 1992, 1993, and 1994. These time series were...

  3. [Somatotype-dependent cardiorespiratory system adaption in children and adolsescents in the north-east of Russia].

    Science.gov (United States)

    Bartosh, O P; Sokolov, A Ia

    2006-01-01

    The authors have revealed the tension of cardiovascular performance in 11-14-year-old children and adolescents with the macrosomatotype (MaS) and a lower bronchial patency in 13-14-year-old adolescents in the winter-spring period. This points to the decreased reserves of the cardiorespiratory system in the teenagers with MaS during their adaptation the environment of the north-east of Russia. PMID:17190063

  4. An investigation into the clinical reasoning of cardiorespiratory physiotherapists using a simulated patient and simulated high dependency unit

    OpenAIRE

    Thackray, Debbie

    2014-01-01

    The ability of physiotherapists to make clinical decisions is understood to be a vital component of achieving expertise and is part of being an autonomous practitioner, yet this complex phenomenon has been under-researched in cardiorespiratory physiotherapy. Educators in this field need to understand what method of clinical reasoning clinicians are using, so that educational strategies can be designed to facilitate the development of clinical reasoning by undergraduate physiotherapy students ...

  5. Assessment of cardio-respiratory interactions in preterm infants by bivariate autoregressive modeling and surrogate data analysis

    OpenAIRE

    Indic, Premananda; Bloch-Salisbury, Elisabeth; Bednarek, Frank; Emery N Brown; Paydarfar, David; Barbieri, Riccardo

    2011-01-01

    Background: Cardio-respiratory interactions are weak at the earliest stages of human development, suggesting that assessment of their presence and integrity may be an important indicator of development in infants. Despite the valuable research devoted to infant development, there is still a need for specifically targeted standards and methods to assess cardiopulmonary functions in the early stages of life. We present a new methodological framework for the analysis of cardiovascular variables ...

  6. Fit for Life.

    Science.gov (United States)

    Vail, Kathleen

    1999-01-01

    Children who hate gym grow into adults who associate physical activity with ridicule and humiliation. Physical education is reinventing itself, stressing enjoyable activities that continue into adulthood: aerobic dance, weight training, fitness walking, mountain biking, hiking, inline skating, karate, rock-climbing, and canoeing. Cooperative,…

  7. The universal Higgs fit

    DEFF Research Database (Denmark)

    Giardino, P. P.; Kannike, K.; Masina, I.;

    2014-01-01

    We perform a state-of-the-art global fit to all Higgs data. We synthesise them into a 'universal' form, which allows to easily test any desired model. We apply the proposed methodology to extract from data the Higgs branching ratios, production cross sections, couplings and to analyse composite...

  8. Kids Weigh to Fitness.

    Science.gov (United States)

    Maione, Mary Jane

    A description is given of a program that provides preventive measures to check obesity in children and young people. The 24-week program is divided into two parts--a nutrition component and an exercise component. At the start and end of the program, tests are given to assess the participants' height, weight, body composition, fitness level, and…

  9. Fitting a Gompertz curve

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans)

    1994-01-01

    textabstractIn this paper, a simple Gompertz curve-fitting procedure is proposed. Its advantages include the facts that the stability of the saturation level over the sample period can be checked, and that no knowledge of its value is necessary for forecasting. An application to forecasting the stoc

  10. Fit for work

    DEFF Research Database (Denmark)

    Brorholt, Grete

    "Fit for work - Attraktiv sundhed og sikkerhed på en hospitalsafdeling i Region Hovedstaden" undersøger hvorledes sundhedsvæsenets forandringer påvirker medarbejdere, ledere og organisation. Udgangspunktet for afhandlingen er en interesse for psykisk arbejdsmiljø, og hvordan reformerne i kølvandet...

  11. Finding What Fits

    Science.gov (United States)

    Casey, Stephanie A.

    2016-01-01

    Statistical association between two variables is one of the fundamental statistical ideas in school curricula. Reasoning about statistical association has been deemed one of the most important cognitive activities that humans perform. Students are typically introduced to statistical association through the study of the line of best fit because it…

  12. Lack of Association of Estrogen Receptor Alpha Gene Polymorphisms with Cardiorespiratory and Metabolic Variables in Young Women

    Directory of Open Access Journals (Sweden)

    Mario Hirata

    2012-10-01

    Full Text Available This study examined the association of estrogen receptor alpha gene (ESR1 polymorphisms with cardiorespiratory and metabolic parameters in young women. In total, 354 healthy women were selected for cardiopulmonary exercise testing and short-term heart rate (HR variability (HRV evaluation. The HRV analysis was determined by the temporal indices rMSSD (square root of the mean squared differences of successive R–R intervals (RRi divided by the number of RRi minus one, SDNN (root mean square of differences from mean RRi, divided by the number of RRi and power spectrum components by low frequency (LF, high frequency (HF and LF/HF ratio. Blood samples were obtained for serum lipids, estradiol and DNA extraction. ESR1 rs2234693 and rs9340799 polymorphisms were analyzed by PCR and fragment restriction analysis. HR and oxygen uptake (VO2 values did not differ between the ESR1 polymorphisms with respect to autonomic modulation. We not find a relationship between ESR1 T–A, T–G, C–A and C–G haplotypes and cardiorespiratory and metabolic variables. Multiple linear regression analysis demonstrated that VO2, total cholesterol and triglycerides influence HRV (p < 0.05. The results suggest that ESR1 variants have no effect on cardiorespiratory and metabolic variables, while HRV indices are influenced by aerobic capacity and lipids in healthy women.

  13. Branchial O(2) chemoreceptors in Nile tilapia Oreochromis niloticus: Control of cardiorespiratory function in response to hypoxia.

    Science.gov (United States)

    Zeraik, Vivian M; Belão, Thiago C; Florindo, Luiz Henrique; Kalinin, Ana L; Rantin, F Tadeu

    2013-09-01

    This study examined the distribution and orientation of gill O(2) chemoreceptors in Oreochromis niloticus and their role in cardiorespiratory responses to graded hypoxia. Intact fish, and a group with the first gill arch excised (operated), were submitted to graded hypoxia and their cardiorespiratory responses (oxygen uptake - V˙O(2) , breathing frequency - fR, ventilatory stroke volume - VT, gill ventilation - V˙G, O(2) extraction from the ventilatory current - EO(2) , and heart rate - fH) were compared. Their responses to bolus injections of NaCN into the bloodstream (internal) or ventilatory water stream (external) were also determined. The V˙O(2) of operated fish was significantly lower at the deepest levels of hypoxia. Neither reflex bradycardia nor ventilatory responses were completely abolished by bilateral excision of the first gill arch. EO(2) of the operated group was consistently lower than the intact group. The responses to internal and external NaCN included transient decreases in fH and increases in fR and Vamp (ventilation amplitude). These cardiorespiratory responses were attenuated but not abolished in the operated group, indicating that chemoreceptors are not restricted to the first gill arch, and are sensitive to oxygen levels in both blood and water.

  14. Investigating factors influencing 4th-year physiotherapy students' opinions of cardiorespiratory physiotherapy as a career path.

    Science.gov (United States)

    Reeve, Julie; Skinner, Margot; Lee, Annemarie; Wilson, Lisa; Alison, Jennifer A

    2012-07-01

    Recruitment and retention issues in cardiorespiratory physiotherapy (CRP) have led to concerns for the future of this specialist area of physiotherapy. This study evaluated the career choices of student physiotherapists and elicited factors that influenced their perceptions of CRP. A postal questionnaire to two schools of physiotherapy in New Zealand and two in Australia was administered. Final year students were randomly selected and invited to complete the questionnaire. Details of respondents' clinical experience, future career intentions, and perceptions of CRP as a specialism were ascertained. A response rate of 61% (n=149) was obtained. Although the majority of respondents had undertaken cardiorespiratory placements, only 3% of respondents reported being "extremely interested" in specializing in CRP. The variety and timing of clinical placements and educational and clinical supervision were key factors that had the potential to both positively and negatively influence students' opinions of CRP. An understanding of the role of CRP beyond that of inpatient care appeared limited. To promote uptake of CRP as a career option, clinicians, educators, and managers should strive to provide positive clinical placements and educational opportunities. The extensive scope of clinical practice of cardiorespiratory physiotherapists could be a greater focus within physiotherapy curricula. PMID:22007799

  15. Excitatory amino acid transporters tonically restrain nTS synaptic and neuronal activity to modulate cardiorespiratory function.

    Science.gov (United States)

    Matott, Michael P; Ruyle, Brian C; Hasser, Eileen M; Kline, David D

    2016-03-01

    The nucleus tractus solitarii (nTS) is the initial central termination site for visceral afferents and is important for modulation and integration of multiple reflexes including cardiorespiratory reflexes. Glutamate is the primary excitatory neurotransmitter in the nTS and is removed from the extracellular milieu by excitatory amino acid transporters (EAATs). The goal of this study was to elucidate the role of EAATs in the nTS on basal synaptic and neuronal function and cardiorespiratory regulation. The majority of glutamate clearance in the central nervous system is believed to be mediated by astrocytic EAAT 1 and 2. We confirmed the presence of EAAT 1 and 2 within the nTS and their colocalization with astrocytic markers. EAAT blockade withdl-threo-β-benzyloxyaspartic acid (TBOA) produced a concentration-related depolarization, increased spontaneous excitatory postsynaptic current (EPSC) frequency, and enhanced action potential discharge in nTS neurons. Solitary tract-evoked EPSCs were significantly reduced by EAAT blockade. Microinjection of TBOA into the nTS of anesthetized rats induced apneic, sympathoinhibitory, depressor, and bradycardic responses. These effects mimicked the response to microinjection of exogenous glutamate, and glutamate responses were enhanced by EAAT blockade. Together these data indicate that EAATs tonically restrain nTS excitability to modulate cardiorespiratory function.

  16. Can Programmed or Self-Selected Physical Activity Affect Physical Fitness of Adolescents?

    Directory of Open Access Journals (Sweden)

    Neto Cláudio F.

    2014-12-01

    Full Text Available The aim of this study was to verify the effects of programmed and self-selected physical activities on the physical fitness of adolescents. High school adolescents, aged between 15 and 17 years, were divided into two experimental groups: a a self-selected physical activity group (PAS with 55 students (aged 15.7 ± 0.7 years, who performed physical activities with self-selected rhythm at the following sports: basketball, volleyball, handball, futsal and swimming; and b a physical fitness training group (PFT with 53 students (aged 16.0 ± 0.7 years, who performed programmed physical fitness exercises. Both types of activity were developed during 60 min classes. To assess physical fitness the PROESP-BR protocol was used. The statistical analysis was performed by repeated measures ANOVA. The measurements of pre and post-tests showed significantly different values after PFT in: 9 minute running test, medicine ball throw, horizontal jump, abdominal endurance, running speed and flexibility. After PAS differences were detected in abdominal endurance, agility, running speed and flexibility. The intervention with programmed physical activity promoted more changes in the physical abilities; however, in the self-selected program, agility was improved probably because of the practice of sports. Therefore, physical education teachers can use PFT to improve cardiorespiratory fitness and power of lower and upper limbs and PAS to improve agility of high school adolescents.

  17. Effects of exercise intervention on the functional fitness of community elderly

    Directory of Open Access Journals (Sweden)

    Lee Tsui-Er

    2016-01-01

    Full Text Available This study aims to discuss the effects of the 12-week exercise intervention on the functional fitness of community elderly. Total 25 community elderly aged above 65 are proceeded functional fitness tests. The data are analyzed with Descriptive Statistics. The results show that the male elderly significantly enhance the upper limb strength (musculus biceps brachii left arm curling, musculus biceps brachii right arm curling, static balance (open-eye single leg standing, and agility and dynamic balance (chair stand detour and the female elderly make remarkable progress on the upper limb strength (musculus biceps brachii left arm curling, musculus biceps brachii right arm curling, cardiorespiratory endurance (high knees in place, static balance (open-eye single leg standing, and agility and dynamic balance (chair stand detour after the 12-week regular exercise intervention. With functional fitness tests, the research findings reveal that regular exercise presents the effectiveness on distinct physical fitness of community elderly, while the aerobic endurance and upper/lower body flexibility still require improvement. Apparently, it is suggested to practice courses with stages and match fitness test results to adjust types of exercise and exercise intensity in order to achieve the effect.

  18. Extensive fitness and human cooperation.

    Science.gov (United States)

    van Hateren, J H

    2015-12-01

    Evolution depends on the fitness of organisms, the expected rate of reproducing. Directly getting offspring is the most basic form of fitness, but fitness can also be increased indirectly by helping genetically related individuals (such as kin) to increase their fitness. The combined effect is known as inclusive fitness. Here it is argued that a further elaboration of fitness has evolved, particularly in humans. It is called extensive fitness and it incorporates producing organisms that are merely similar in phenotype. The evolvability of this mechanism is illustrated by computations on a simple model combining heredity and behaviour. Phenotypes are driven into the direction of high fitness through a mechanism that involves an internal estimate of fitness, implicitly made within the organism itself. This mechanism has recently been conjectured to be responsible for producing agency and goals. In the model, inclusive and extensive fitness are both implemented by letting fitness increase nonlinearly with the size of subpopulations of similar heredity (for the indirect part of inclusive fitness) and of similar phenotype (for the phenotypic part of extensive fitness). Populations implementing extensive fitness outcompete populations implementing mere inclusive fitness. This occurs because groups with similar phenotype tend to be larger than groups with similar heredity, and fitness increases more when groups are larger. Extensive fitness has two components, a direct component where individuals compete in inducing others to become like them and an indirect component where individuals cooperate and help others who are already similar to them.

  19. Differences in muscle strength after ACL reconstruction do not influence cardiorespiratory responses to isometabolic exercise

    Directory of Open Access Journals (Sweden)

    Marília S. Andrade

    2014-05-01

    Full Text Available Objectives: To investigate whether the muscle strength decrease that follows anterior cruciate ligament (ACL reconstruction would lead to different cardiorespiratory adjustments during dynamic exercise. Method: Eighteen active male subjects were submitted to isokinetic evaluation of knee flexor and extensor muscles four months after ACL surgery. Thigh circumference was also measured and an incremental unilateral cardiopulmonary exercise test was performed separately for both involved and uninvolved lower limbs in order to compare heart rate, oxygen consumption, minute ventilation, and ventilatory pattern (breath rate, tidal volume, inspiratory time, expiratory time, tidal volume/inspiratory time at three different workloads (moderate, anaerobic threshold, and maximal. Results: There was a significant difference between isokinetic extensor peak torque measured in the involved (116.5±29.1 Nm and uninvolved (220.8±40.4 Nm limbs, p=0.000. Isokinetic flexor peak torque was also lower in the involved limb than in the uninvolved limb (107.8±15.4 and 132.5±26.3 Nm, p=0.004, respectively. Lower values were also found in involved thigh circumference as compared with uninvolved limb (46.9±4.3 and 48.5±3.9 cm, p=0.005, respectively. No differences were found between the lower limbs in any of the variables of the incremental cardiopulmonary tests at all exercise intensities. Conclusions: Our findings indicate that, four months after ACL surgery, there is a significant deficit in isokinetic strength in the involved limb, but these differences in muscle strength requirement do not produce differences in the cardiorespiratory adjustments to exercise. Based on the hypotheses from the literature which explain the differences in the physiological responses to exercise for different muscle masses, we can deduce that, after 4 months of a rehabilitation program after an ACL reconstruction, individuals probably do not present differences in muscle oxidative and

  20. Local search heuristics: Fitness Cloud versus Fitness Landscape

    OpenAIRE

    Collard, Philippe; Verel, Sébastien; Clergue, Manuel

    2004-01-01

    International audience This paper introduces the concept of fitness cloud as an alternative way to visualize and analyze search spaces than given by the geographic notion of fitness landscape. It is argued that the fitness cloud concept overcomes several deficiencies of the landscape representation. Our analysis is based on the correlation between fitness of solutions and fitnesses of nearest solutions according to some neighboring. We focus on the behavior of local search heuristics, such...

  1. Computational radiology in skeletal radiography

    Energy Technology Data Exchange (ETDEWEB)

    Peloschek, Ph.; Nemec, S. [Computational Image Analysis and Radiology Lab (CIR), Department of Radiology, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria); Widhalm, P. [Computational Image Analysis and Radiology Lab (CIR), Department of Radiology, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria); Pattern Recognition and Image Processing Group, Department of Computer Aided Automation, Vienna University of Technology, Wiedner Hauptstrasse 8-10/020, A-1040 Vienna (Austria); Donner, R. [Computational Image Analysis and Radiology Lab (CIR), Department of Radiology, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria); Pattern Recognition and Image Processing Group, Department of Computer Aided Automation, Vienna University of Technology, Wiedner Hauptstrasse 8-10/020, A-1040 Vienna (Austria); Institute for Computer Graphics and Vision, Graz University of Technology, Inffeldgasse 16, A-8010 Graz (Austria); Birngruber, E. [Computational Image Analysis and Radiology Lab (CIR), Department of Radiology, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria); Thodberg, H.H. [Visiana Aps, Sollerodvej 57C, DK-2840 Holte (Denmark); Kainberger, F. [Computational Image Analysis and Radiology Lab (CIR), Department of Radiology, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria); Langs, G. [Computational Image Analysis and Radiology Lab (CIR), Department of Radiology, Medical University Vienna, Waehringer Guertel 18-20, A-1090 Vienna (Austria)], E-mail: georg.langs@meduniwien.ac.at

    2009-11-15

    Recent years have brought rapid developments in computational image analysis in musculo-skeletal radiology. Meanwhile the algorithms have reached a maturity that makes initial clinical use feasible. Applications range from joint space measurement to erosion quantification, and from fracture detection to the assessment of alignment angles. Current results of computational image analysis in radiography are very promising, but some fundamental issues remain to be clarified, among which the definition of the optimal trade off between automatization and operator-dependency, the integration of these tools into clinical work flow and last not least the proof of incremental clinical benefit of these methods.

  2. Computational radiology in skeletal radiography

    International Nuclear Information System (INIS)

    Recent years have brought rapid developments in computational image analysis in musculo-skeletal radiology. Meanwhile the algorithms have reached a maturity that makes initial clinical use feasible. Applications range from joint space measurement to erosion quantification, and from fracture detection to the assessment of alignment angles. Current results of computational image analysis in radiography are very promising, but some fundamental issues remain to be clarified, among which the definition of the optimal trade off between automatization and operator-dependency, the integration of these tools into clinical work flow and last not least the proof of incremental clinical benefit of these methods.

  3. The prevalence of heat-related cardiorespiratory symptoms: the vulnerable groups identified from the National FINRISK 2007 Study

    Science.gov (United States)

    Näyhä, Simo; Rintamäki, Hannu; Donaldson, Gavin; Hassi, Juhani; Jousilahti, Pekka; Laatikainen, Tiina; Jaakkola, Jouni J. K.; Ikäheimo, Tiina M.

    2016-09-01

    The prevalence of heat-related cardiorespiratory symptoms among vulnerable groups is not well known. We therefore estimated the prevalence of heat-related cardiorespiratory symptoms among the Finnish population and their associations with social and individual vulnerability factors. The data came from the National FINRISK 2007 Study, in which 4007 men and women aged 25-74 answered questions on heat-related cardiorespiratory symptoms in the Oulu Cold and Heat Questionnaire 2007. Logistic regression was used to calculate odds ratios (ORs), their 95 % confidence intervals (CIs), and model-predicted prevalence figures. The prevalence of heat-related cardiorespiratory symptoms was 12 %. It increased with age, from 3 % at the age of 25 years to 28 % at the age of 75 years. The symptoms were associated with pre-existing lung (OR 3.93; CI 3.01-5.13) and cardiovascular diseases (OR 2.27; 1.78-2.89); being a pensioner (OR 2.91; 1.65-5.28), unemployed (OR 2.82; 1.47-5.48), or working in agriculture (OR 2.27; 1.14-4.46) compared with working in industry; having only basic vs academic education (OR 1.98; 1.31-3.05); being female (OR 1.94; 1.51-2.50); being heavy vs light alcohol consumer (OR 1.89; 1.02-3.32); undertaking hard vs light physical work (OR 1.48;1.06-2.07); and being inactive vs active in leisure time (OR 1.97; 1.39-2.81). The adjusted prevalence of symptoms showed a wide range of variation, from 3 to 61 % depending on sex, age, professional field, education, and pre-existing lung and cardiovascular diseases. In conclusion, heat-related cardiorespiratory symptoms are commonly perceived among people with pre-existing lung or cardiovascular disease, agricultural workers, unemployed, pensioners, and people having only basic education. This information is needed for any planning and targeting measures to reduce the burden of summer heat.

  4. Expression of Gla proteins during fish skeletal development

    OpenAIRE

    Gavaia, Paulo J.

    2006-01-01

    Senegal sole skeletal development; Skeletal malformations; Skeletal malformation in mediterranean species; Senegal sole skeletal deformities; Zebra fish as model system: skeletal development; Identification of bone cells / skeletal development; Spatial - temporal pattern of bgp expression; Single cell resolution: localization of bgp mRNA; Single cell resolution: Immunolocalization of Bgp; Single cell resolution: localization of mgp mRNA; Single cell resolution: Immunolocalization of Mgp; An i...

  5. Extensive fitness and human cooperation

    NARCIS (Netherlands)

    van Hateren, J. H.

    2015-01-01

    Evolution depends on the fitness of organisms, the expected rate of reproducing. Directly getting offspring is the most basic form of fitness, but fitness can also be increased indirectly by helping genetically related individuals (such as kin) to increase their fitness. The combined effect is known

  6. Virtual Fitting Rooms

    OpenAIRE

    Becerra Rodríguez, Carlos Alfredo

    2016-01-01

    In the last decade a considerable number of efforts have been devoted into developing Virtual Fitting Rooms (VFR) due to the great popularity of Virtual Reality (VR) and Augmented Reality (AR) in the fashion design industry. The existence of new technologies such as Kinect, powerful web cameras and smartphones permit us to examine new ways to try on clothes without doing it physically in a store center. This research is primarily dedicated to review some important aspects about...

  7. Physical Fitness and Pregnancy

    OpenAIRE

    Thorell, Eva

    2013-01-01

    Objectives To assess physical fitness in pregnancy and to evaluate its effect on perceived health, back pain, blood pressure and duration of gestation. Also, to evaluate the effect of serum relaxin levels on blood pressure and duration of gestation. Material and methods A prospective cohort of 520 pregnant women were examined in early pregnancy and five months postpartum with regard to socio-demographic characteristics and estimated peak oxygen uptake (V̇O2 peak, est.). Serum concentrations o...

  8. BESⅢ track fitting algorithm

    Institute of Scientific and Technical Information of China (English)

    WANG Ji-Ke; MAO Ze-Pu; BIAN Jian-Ming; CAO Guo-Fu; CAO Xue-Xiang; CHEN Shen-Jian; DENG Zi-Yan; FU Cheng-Dong; GAO Yuan-Ning; HE Kang-Lin; HE Miao; HUA Chun-Fei; HUANG Bin; HUANG Xing-Tao; JI Xiao-Sin; LI Fei; LI Hai-Bo; LI Wei-Dong; LIANG Yu-Tie; LIU Chun-Xiu; LIU Huai-Min; LIU Suo; LIU Ying-Jie; MA Qiu-Mei; MA Xiang; MAO Ya-Jun; MO Xiao-Hu; PAN Ming-Hua; PANG Cai-Ying; PING Rong-Gang; QIN Ya-Hong; QIU Jin-Fa; SUN Sheng-Sen; SUN Yong-Zhao; WANG Liang-Liang; WEN Shuo-Pin; WU Ling-Hui; XIE Yu-Guang; XU Min; YAN Liang; YOU Zheng-Yun; YUAN Chang-Zheng; YUAN Ye; ZHANG Bing-Yun; ZHANG Chang-Chun; ZHANG Jian-Yong; ZHANG Xue-Yao; ZHANG Yao; ZHENG Yang-Heng; ZHU Ke-Jun; ZHU Yong-Sheng; ZHU Zhi-Li; ZOU Jia-Heng

    2009-01-01

    A track fitting algorithm based on the Kalman filter method has been developed for BESⅢ of BEPCⅡ.The effects of multiple scattering and energy loss when the charged particles go through the detector,non-uniformity of magnetic field (NUMF) and wire sag, etc., have been carefully handled.This algorithm works well and the performance satisfies the physical requirements tested by the simulation data.

  9. Made to fit

    DEFF Research Database (Denmark)

    Bjerck, Mari; Klepp, Ingun Grimstad; Skoland, Eli

    Denne rapporten formidler funn fra en litteraturstudie, brukerundersøkelse og markedsundersøkelse gjort i prosjektet Made to Fit. Rapporten svarer på prosjektets hovedmål og delmål som retter seg mot å formidle kunnskap om tilpasning og fremstilling av funksjonelle og gode produkter for handikapp......Denne rapporten formidler funn fra en litteraturstudie, brukerundersøkelse og markedsundersøkelse gjort i prosjektet Made to Fit. Rapporten svarer på prosjektets hovedmål og delmål som retter seg mot å formidle kunnskap om tilpasning og fremstilling av funksjonelle og gode produkter...... for handikappede. Herunder potensialet for å utvikle spesialtilpassede klær i konseptet «Made to Fit», utprøving av metoder og identifisering av kunnskapsstatus på feltet. Rapporten er således delt inn i tre hoveddeler. Første delen bygger videre på prosjektnotatet til Vestvik, Hebrok og Klepp (2013) fra...

  10. Skeletal stem cells in space and time

    DEFF Research Database (Denmark)

    Kassem, Moustapha; Bianco, Paolo

    2015-01-01

    The nature, biological characteristics, and contribution to organ physiology of skeletal stem cells are not completely determined. Chan et al. and Worthley et al. demonstrate that a stem cell for skeletal tissues, and a system of more restricted, downstream progenitors, can be identified in mice ...

  11. Early prenatal diagnosis of skeletal anomalies

    NARCIS (Netherlands)

    A. Khalil; E. Pajkrt; L.S. Chitty

    2011-01-01

    Objective To review experience of early prenatal diagnosis of skeletal dysplasias, and to explore diagnostic accuracy and improve management. Methods A retrospective review of fetal medicine unit (FMU) records was performed to identify cases where a skeletal dysplasia was suspected by 14 weeks' gest

  12. Mechanical modeling of skeletal muscle functioning.

    NARCIS (Netherlands)

    Linden, van der Bart Jochem Julius Joost

    1998-01-01

    For movement of body or body segments is combined effort needed of the central nervous system and the muscular-skeletal system. This thesis deals with the mechanical functioning of skeletal muscle. That muscles come in a large variety of geometries, suggest the existence of a relation between muscle

  13. Cardio-respiratory and daily activity monitor based on FMCW Doppler radar embedded in a wheelchair.

    Science.gov (United States)

    Postolache, Octavian; Girão, Pedro Silva; Postolache, Gabriela; Gabriel, Joaquim

    2011-01-01

    Unobtrusive monitoring of the cardio-respiratory and daily activity for wheelchair users became nowadays an important challenge, considering population aging phenomena and the increasing of the elderly with chronic diseases that affect their motion capabilities. This work reports the utilization of FMCW (frequency modulated continuous wave) Doppler radar sensors embedded in a manual wheelchair to measure the cardiac and respiratory activities and the physical activity of the wheelchair user. Another radar sensor is included in the system in order to quantify the motor activity through the wheelchair traveled distance, when the user performs the manual operation of the wheelchair. A conditioning circuit including active filters and a microcontroller based primary processing module was designed and implemented to deliver the information through Bluetooth communication protocol to an Android OS tablet computer. The main capabilities of the software developed using Android SDK and Java were the signal processing of Doppler radar measurement channel signals, graphical user interface, data storage and Wi-Fi data synchronization with remote physiological and physical activity database. PMID:22254706

  14. Currents issues in cardiorespiratory care of patients with post-polio syndrome

    Directory of Open Access Journals (Sweden)

    Marco Orsini

    2016-07-01

    Full Text Available ABSTRACT Post-polio syndrome (PPS is a condition that affects polio survivors years after recovery from an initial acute attack of the poliomyelitis virus. Most often, polio survivors experience a gradual new weakening in muscles that were previously affected by the polio infection. The actual incidence of cardiovascular diseases (CVDs in individuals suffering from PPS is not known. However, there is a reason to suspect that individuals with PPS might be at increased risk. Method A search for papers was made in the databases Bireme, Scielo and Pubmed with the following keywords: post polio syndrome, cardiorespiratory and rehabilitation in English, French and Spanish languages. Although we targeted only seek current studies on the topic in question, only the relevant (double-blind, randomized-controlled and consensus articles were considered. Results and Discussion Certain features of PPS such as generalized fatigue, generalized and specific muscle weakness, joint and/or muscle pain may result in physical inactivity deconditioning obesity and dyslipidemia. Respiratory difficulties are common and may result in hypoxemia. Conclusion Only when evaluated and treated promptly, somE patients can obtain the full benefits of the use of respiratory muscles aids as far as quality of life is concerned.

  15. Information Decomposition in Bivariate Systems: Theory and Application to Cardiorespiratory Dynamics

    Directory of Open Access Journals (Sweden)

    Luca Faes

    2015-01-01

    Full Text Available In the framework of information dynamics, the temporal evolution of coupled systems can be studied by decomposing the predictive information about an assigned target system into amounts quantifying the information stored inside the system and the information transferred to it. While information storage and transfer are computed through the known self-entropy (SE and transfer entropy (TE, an alternative decomposition evidences the so-called cross entropy (CE and conditional SE (cSE, quantifying the cross information and internal information of the target system, respectively. This study presents a thorough evaluation of SE, TE, CE and cSE as quantities related to the causal statistical structure of coupled dynamic processes. First, we investigate the theoretical properties of these measures, providing the conditions for their existence and assessing the meaning of the information theoretic quantity that each of them reflects. Then, we present an approach for the exact computation of information dynamics based on the linear Gaussian approximation, and exploit this approach to characterize the behavior of SE, TE, CE and cSE in benchmark systems with known dynamics. Finally, we exploit these measures to study cardiorespiratory dynamics measured from healthy subjects during head-up tilt and paced breathing protocols. Our main result is that the combined evaluation of the measures of information dynamics allows to infer the causal effects associated with the observed dynamics and to interpret the alteration of these effects with changing experimental conditions.

  16. Large hiatal hernia at chest radiography in a woman with cardiorespiratory symptoms.

    Science.gov (United States)

    Torres, Daniele; Parrinello, Gaspare; Cardillo, Mauro; Pomilla, Marina; Trapanese, Caterina; Michele, Bellanca; Lupo, Umberto; Schimmenti, Caterina; Cuttitta, Francesco; Pietrantoni, Rossella; Vogiatzis, Danai; Licata, Giuseppe

    2012-11-01

    Hiatal hernia (HH) is a frequent entity. Rarely, it may exert a wide spectrum of clinical presentations mimicking acute cardiovascular events such as angina-like chest pain until manifestations of cardiac compression that can include postprandial syncope, exercise intolerance, respiratory function, recurrent acute heart failure, and hemodynamic collapse. A 69-year-old woman presented to the emergency department complaining of fatigue on exertion, cough, and episodes of restrosternal pain with less than 1 hour of duration. Her medical history only included some episodes of bronchitis and no history of hypertension. The 12-lead electrocardiogram demonstrated sinus rhythm with right bundle-branch block. Laboratory tests, including cardiac troponin I, were within normal reference values. Chest radiography showed no significant pulmonary alterations and revealed in mediastinum a huge abnormal shadow overlapping the right heart compatible with a gastric bubble.The gastroscopy confirmed a large HH. A 2-dimensional transthoracic echocardiogram, using all standard and modified apical and parasternal views, revealed an echolucent mass, compatible with HH, compressing the right atrium. Also, it showed an altered left ventricular relaxation and a mild increase of pulmonary artery pressure (35 mm Hg). Spirometry showed a mild obstruction of the small airways, whereas coronary angiography showed normal coronary arteries. We concluded that the patient's symptomatology was related to the compressive effects of the large hiatal ernia, a neglected cause of cardiorespiratory symptoms. The surgical repair of HH was indicated.

  17. Defective skeletal mineralization in pediatric CKD.

    Science.gov (United States)

    Wesseling-Perry, Katherine

    2015-04-01

    Although traditional diagnosis and treatment of renal osteodystrophy focused on changes in bone turnover, current data demonstrate that abnormalities in skeletal mineralization are also prevalent in pediatric chronic kidney disease (CKD) and likely contribute to skeletal morbidities that continue to plague this population. It is now clear that alterations in osteocyte biology, manifested by changes in osteocytic protein expression, occur in early CKD before abnormalities in traditional measures of mineral metabolism are apparent and may contribute to defective skeletal mineralization. Current treatment paradigms advocate the use of 1,25(OH)2vitamin D for the control of secondary hyperparathyroidism; however, these agents fail to correct defective skeletal mineralization and may exacerbate already altered osteocyte biology. Further studies are critically needed to identify the initial trigger for abnormalities of skeletal mineralization as well as the potential effects that current therapeutic options may have on osteocyte biology and bone mineralization.

  18. Assessment of mandibular growth by skeletal scintigraphy

    International Nuclear Information System (INIS)

    Accurate assessment of facial skeletal growth remains a major problem in craniomaxillofacial surgery. Current methods include: (1) comparisons of chronologic age with growth histories of the patient and the family, (2) hand-wrist radiographs compared with a standard, and (3) serial cephalometric radiographs. Uptake of technetium-99m methylene diphosphonate into bone is a reflection of current metabolic activity and blood flow. Therefore, scintigraphy with this radiopharmaceutical might serve as a good method of assessing skeletal growth. Thirty-four patients, ranging in age from 15 months to 22 years, who were undergoing skeletal scintigrams for acute pathologic conditions of the extremities, were used to develop standards of uptake based on age and skeletal maturation. The results indicate that skeletal scintigraphy may be useful in evaluation of mandibular growth

  19. Cardiac, Skeletal, and smooth muscle mitochondrial respiration

    DEFF Research Database (Denmark)

    Park, Song-Young; Gifford, Jayson R; Andtbacka, Robert H I;

    2014-01-01

    Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial function. Therefore, this study examined mitochondrial respiratory rates in the smooth muscle of healthy human feed arteries and compared with that of healthy cardiac and skeletal muscle. Cardiac......, skeletal, and smooth muscle was harvested from a total of 22 subjects (53±6 yrs) and mitochondrial respiration assessed in permeabilized fibers. Complex I+II, state 3 respiration, an index of oxidative phosphorylation capacity, fell progressively from cardiac, skeletal, to smooth muscle (54±1; 39±4; 15......±1 pmol•s(-1)•mg (-1), pmitochondrial density, also fell progressively from cardiac, skeletal, to smooth muscle (222±13; 115±2; 48±2 umol•g(-1)•min(-1), p

  20. Cardiorespiratory response to physical exercise and psychological variables in panic disorder A resposta cardiorrespiratória ao exercício e variáveis psicológicas no transtorno do pânico

    Directory of Open Access Journals (Sweden)

    Daniela Caldirola

    2011-12-01

    Full Text Available OBJECTIVE: To investigate the possible influence of psychological variables on cardiorespiratory responses and perceived exertion of patients with Panic Disorder (PD during a submaximal exercise test. METHOD: Ten outpatients with PD and 10 matched healthy subjects walked up on a treadmill slope at a speed of 4 km/h in order to reach 65% of their maximum heart rate. Cardiorespiratory variables were continuously recorded. Before the exercise, the state and trait anxiety (State-Trait Anxiety Inventory scores, fear of physical sensations (Body Sensation Questionnaire scores, and fear of autonomic arousal (Anxiety Sensitivity Index scores were assessed; during the exercise, levels of anxiety (VAS-A and exertion (Borg Scale CR 10 were measured. RESULTS: Compared to controls, patients reached earlier the target HR and the ventilatory threshold, showed lower oxygen consumption, higher HR and lower within-subject standard deviations of HR (a measure of cardiac variability. Exertion was also higher, and there was a significant correlation between breathing frequency, tidal volume and HR. No significant associations were found between cardiorespiratory response, perceived exertion, and psychological variables in patients with PD. CONCLUSION: Although patients with PD presented poor cardiorespiratory fitness and were required to spend more effort during physical exercise, this did not appear to be related to the psychological variables considered. Further studies with larger groups are warranted.OBJETIVO: Investigar a possível influência de variáveis psicológicas na resposta cardiorrespiratória e percepção de esforço dos pacientes com Transtorno do Pânico (TP durante exercício físico de intensidade submáxima. MÉTODO: Dez pacientes ambulatoriais com TP e dez controles saudáveis foram submetidos a uma caminhada na velocidade de 4 km/h em uma rampa inclinada. A inclinação da rampa foi aumentada até que fosse atingida 65% da frequência card

  1. Invasion fitness, inclusive fitness, and reproductive numbers in heterogeneous populations.

    Science.gov (United States)

    Lehmann, Laurent; Mullon, Charles; Akçay, Erol; Van Cleve, Jeremy

    2016-08-01

    How should fitness be measured to determine which phenotype or "strategy" is uninvadable when evolution occurs in a group-structured population subject to local demographic and environmental heterogeneity? Several fitness measures, such as basic reproductive number, lifetime dispersal success of a local lineage, or inclusive fitness have been proposed to address this question, but the relationships between them and their generality remains unclear. Here, we ascertain uninvadability (all mutant strategies always go extinct) in terms of the asymptotic per capita number of mutant copies produced by a mutant lineage arising as a single copy in a resident population ("invasion fitness"). We show that from invasion fitness uninvadability is equivalently characterized by at least three conceptually distinct fitness measures: (i) lineage fitness, giving the average individual fitness of a randomly sampled mutant lineage member; (ii) inclusive fitness, giving a reproductive value weighted average of the direct fitness costs and relatedness weighted indirect fitness benefits accruing to a randomly sampled mutant lineage member; and (iii) basic reproductive number (and variations thereof) giving lifetime success of a lineage in a single group, and which is an invasion fitness proxy. Our analysis connects approaches that have been deemed different, generalizes the exact version of inclusive fitness to class-structured populations, and provides a biological interpretation of natural selection on a mutant allele under arbitrary strength of selection.

  2. Fitting of Z' parameters

    OpenAIRE

    Gulov, Alexey; Skalozub, Vladimir

    2010-01-01

    The paper deals with an approach to the model-independent searching for the Z' gauge boson as a virtual state in scattering processes. The relations between the Z' couplings to fermions covering a wide class of models beyond the standard model are found and used. They reduce in an essential way the number of parameters to be fitted in experiments. Special observables which uniquely pick out the Z' at energies of LEP and ILC colliders in different leptonic processes are introduced and the data...

  3. SNP-by-fitness and SNP-by-BMI interactions from seven candidate genes and incident hypertension after 20 years of follow-up: the CARDIA Fitness Study.

    Science.gov (United States)

    Sarzynski, M A; Rankinen, T; Sternfeld, B; Fornage, M; Sidney, S; Bouchard, C

    2011-08-01

    The association of single nucleotide polymorphisms (SNPs) from seven candidate genes, including genotype-by-baseline fitness and genotype-by-baseline body mass index (BMI) interactions, with incident hypertension over 20 years was investigated in 2663 participants (1301 blacks, 1362 whites) of the Coronary Artery Risk Development in Young Adults Study (CARDIA). Baseline cardiorespiratory fitness was determined from duration of a modified Balke treadmill test. A total of 98 SNPs in blacks and 89 SNPs in whites from seven candidate genes were genotyped. Participants that became hypertensive (295 blacks and 146 whites) had significantly higher blood pressure and BMI (both races), and lower fitness (blacks only) at baseline than those who remained normotensive. Markers at the peroxisome proliferative activated receptor gamma coactivator 1α (PPARGC1A) and bradykinin β2 receptor (BDKRB2) genes were nominally associated with greater risk of hypertension, although one marker each at the BDKRB2 and endothelial nitric oxide synthase-3 (NOS3) genes were nominally associated with lower risk. The association of baseline fitness with risk of hypertension was nominally modified by genotype at markers within the angiotensin converting enzyme, angiotensinogen, BDKRB2 and NOS3 genes in blacks and the BDKRB2, endothelin-1 and PPARGC1A genes in whites. BDKRB2 rs4900318 showed nominal interactions with baseline fitness on the risk of hypertension in both races. The association of baseline BMI with risk of hypertension was nominally modified by GNB3 rs2301339 genotype in whites. None of the above associations were statistically significant after correcting for multiple testing. We found that SNPs in these candidate genes did not modify the association between baseline fitness or BMI and risk of hypertension in CARDIA participants. PMID:20944660

  4. PDH regulation in skeletal muscle

    DEFF Research Database (Denmark)

    Kiilerich, Kristian

    Pyruvate dehydrogenase (PDH) decarboxylates pyruvate into acetyl-CoA and links glycolysis with the Krebs cycle. Because PDH is the only step where carbohydrate-derived substrate can enter the mitochondria and become completely oxidized, PDH activity can potentially determine if glycogen / glucose...... is oxidized completely, or whether pyruvate is converted to lactate. Activity of PDH in the active form (PDHa) is overall determined by the degree of PDH-E1? phosphorylation, where PDH-E1? dephosphorylation activates PDH, while PDH-E1? phosphorylation inactivates PDH. The PDH-E1? phosphorylation state...... in mouse skeletal muscle at rest and in response to fasting and during recovery from exercise. The studies indicate that the content of PDH-E1? in human muscle follows the metabolic profile of the muscle, rather than the myosin heavy chain fiber distribution of the muscle. The larger lactate accumulation...

  5. Media device ownership and media use: Associations with sedentary time, physical activity and fitness in English youth.

    Science.gov (United States)

    Sandercock, Gavin R H; Alibrahim, Mohammed; Bellamy, Mark

    2016-12-01

    The aim of this study was to determine whether ownership and use of electronic media were associated with sedentary time and cardiorespiratory fitness (fitness) in youth. We also aimed to determine if associations were independent of physical activity (PA). Fitness was measured using the 20 m shuttle-run. PA, sedentary time, ownership of media devices and media use were self-reported. Participants (n = 678, age 10-15 years) reported daily sedentary time of 620 (± 210) min. Forty-one percent of participants had low PA and 50.4% had low fitness. Higher weekend sedentary time was associated with low fitness in girls (p = 0.005) and boys (p media was associated with higher sedentary time in both sexes and low fitness in girls. High sedentary time was more likely (OR = 5.3, 95%CI: 2.0-14.4) in boys who owned game consoles. Low fitness was more likely in boys who owned digital/satellite TV receivers (OR = 1.8, 95%CI: 1.8-3.2). Schoolchildren spent > 10 h or ~ 85% of each waking day sedentary. Use of social media was associated with higher sedentary time in both sexes and with low fitness in girls. Reducing social media use in youth offers one potential target for intervention. Behaviours associated with sedentary time differed from predictors of low fitness. The complex and often sex-specific interactions identified between sedentary time, PA and fitness suggest the need for carefully targeted interventions to reduce sedentary time and improve fitness in English youth.

  6. Influência da imersão nas respostas cardiorrespiratórias em repouso Influence of immersion on resting cardiorespiratory responses

    Directory of Open Access Journals (Sweden)

    Cristine Lima Alberton

    2009-06-01

    Full Text Available Diversos benefícios nos componentes da aptidão física podem ser adquiridos com a prática de exercícios aquáticos. Além disso, a água proporciona um ambiente para a prática de exercícios com reduzido impacto nos membros inferiores e maior ou menor sobrecarga cardiorrespiratória, de acordo com os movimentos realizados. Porém, tais exercícios podem produzir respostas fisiológicas diferentes daquelas ao ar livre, visto que ocorrem alterações fisiológicas importantes durante a imersão, sendo importante a compreensão das mesmas em repouso para melhor prescrição nesse meio. O presente estudo tem como objetivo revisar estudos sobre o comportamento da frequência cardíaca e do consumo de oxigênio durante a imersão em repouso e compreender os fatores que influenciam nesse comportamento. Várias pesquisas indicam que a frequência cardíaca de repouso é reduzida com a imersão em meio aquático, porém, é importante salientar que fatores tais como temperatura da água, posição corporal, profundidade de imersão e frequência cardíaca inicial podem minimizar ou maximizar tais respostas. Os estudos que abordaram as respostas de consumo de oxigênio não são conclusivos; entretanto, ao contrário da frequência cardíaca, os mesmos indicam semelhante ou maior resposta durante a imersão em repouso. Assim, pode-se concluir que, devido às alterações cardiorrespiratórias verificadas com a imersão em ambiente aquático, a prescrição de exercícios nesse meio deve ser diferenciada daquela para exercícios em ambiente terrestre.Several benefits in the physical fitness components can be acquired with the practice of aquatic exercises. Moreover, water provides an environment for the practice of exercises with reduced impact on lower limbs and major or minor cardiorespiratory overload, depending on the movements performed. However, such exercises can produce physiological responses different from those on dry land, since important

  7. Human skeletal muscle releases leptin in vivo

    DEFF Research Database (Denmark)

    Wolsk, Emil; Grøndahl, Thomas Sahl; Pedersen, Bente Klarlund;

    2012-01-01

    was unaltered. During saline infusion the adipose tissue release averaged 0.8 ± 0.3 ng min(-1) 100g tissue(-1) whereas skeletal muscle release was 0.5 ± 0.1 ng min(-1) 100g tissue(-1). In young healthy humans, skeletal muscle contribution to whole body leptin production could be substantial given the greater...... mass of muscle compared to fat. An understanding of the role that leptin plays in skeletal muscle metabolism may prove important in light of several late-phase trials with recombinant leptin as an anti-obesity drug...

  8. SPECT/CT diagnostics for skeletal infections

    International Nuclear Information System (INIS)

    Skeletal infections are often a diagnostic and clinical challenge. Nuclear imaging modalities used in the diagnostic workup of acute and chronic skeletal infections include three-phase bone scintigraphy and scintigraphy with labelled leucocytes. The introduction of hybrid technologies, such as single photon emission computed tomography/computed tomography (SPECT/CT) has dramatically changed nuclear medical imaging of infections. In general SPECT/CT leads to a considerably more accurate diagnosis than planar or SPECT imaging. Given the integrated acquisition of metabolic, functional and morphological information, SPECT/CT has increased in particular the specificity of three-phase skeletal scanning and scintigraphy with labeled leucocytes. (orig.)

  9. Multifocal skeletal tuberculosis: A case report

    Science.gov (United States)

    ZHANG, LIANG; WANG, JINGCHENG; FENG, XINMIN; TAO, YUPING; YANG, JIANDONG; ZHANG, SHENFEI; CAI, JUN

    2016-01-01

    Tuberculosis (TB) of the musculoskeletal system is a rare clinical condition. Multifocal bone involvement is extremely rare and difficult to recognize. Thus, due to the diverse and atypical clinical manifestations of multifocal skeletal TB, the disease is easy to misdiagnose. In the present study, a rare case of atypical disseminated multifocal skeletal TB was reported, which exhibited uncommon findings in radiological images that were more suggestive of a hematological malignancy or metastatic disease. In conclusion, the diagnosis of this condition by conventional diagnostic methods is challenging. The importance of CT-guided needle biopsy and open biopsy in the diagnosis of skeletal TB was emphasized. PMID:27073438

  10. Heterochrony and early left-right asymmetry in the development of the cardiorespiratory system of snakes.

    Directory of Open Access Journals (Sweden)

    Benjamin J van Soldt

    Full Text Available Snake lungs show a remarkable diversity of organ asymmetries. The right lung is always fully developed, while the left lung is either absent, vestigial, or well-developed (but smaller than the right. A 'tracheal lung' is present in some taxa. These asymmetries are reflected in the pulmonary arteries. Lung asymmetry is known to appear at early stages of development in Thamnophis radix and Natrix natrix. Unfortunately, there is no developmental data on snakes with a well-developed or absent left lung. We examine the adult and developmental morphology of the lung and pulmonary arteries in the snakes Python curtus breitensteini, Pantherophis guttata guttata, Elaphe obsoleta spiloides, Calloselasma rhodostoma and Causus rhombeatus using gross dissection, MicroCT scanning and 3D reconstruction. We find that the right and tracheal lung develop similarly in these species. By contrast, the left lung either: (1 fails to develop; (2 elongates more slowly and aborts early without (2a or with (2b subsequent development of faveoli; (3 or develops normally. A right pulmonary artery always develops, but the left develops only if the left lung develops. No pulmonary artery develops in relation to the tracheal lung. We conclude that heterochrony in lung bud development contributes to lung asymmetry in several snake taxa. Secondly, the development of the pulmonary arteries is asymmetric at early stages, possibly because the splanchnic plexus fails to develop when the left lung is reduced. Finally, some changes in the topography of the pulmonary arteries are consequent on ontogenetic displacement of the heart down the body. Our findings show that the left-right asymmetry in the cardiorespiratory system of snakes is expressed early in development and may become phenotypically expressed through heterochronic shifts in growth, and changes in axial relations of organs and vessels. We propose a step-wise model for reduction of the left lung during snake evolution.

  11. Heterochrony and early left-right asymmetry in the development of the cardiorespiratory system of snakes.

    Science.gov (United States)

    van Soldt, Benjamin J; Metscher, Brian D; Poelmann, Robert E; Vervust, Bart; Vonk, Freek J; Müller, Gerd B; Richardson, Michael K

    2015-01-01

    Snake lungs show a remarkable diversity of organ asymmetries. The right lung is always fully developed, while the left lung is either absent, vestigial, or well-developed (but smaller than the right). A 'tracheal lung' is present in some taxa. These asymmetries are reflected in the pulmonary arteries. Lung asymmetry is known to appear at early stages of development in Thamnophis radix and Natrix natrix. Unfortunately, there is no developmental data on snakes with a well-developed or absent left lung. We examine the adult and developmental morphology of the lung and pulmonary arteries in the snakes Python curtus breitensteini, Pantherophis guttata guttata, Elaphe obsoleta spiloides, Calloselasma rhodostoma and Causus rhombeatus using gross dissection, MicroCT scanning and 3D reconstruction. We find that the right and tracheal lung develop similarly in these species. By contrast, the left lung either: (1) fails to develop; (2) elongates more slowly and aborts early without (2a) or with (2b) subsequent development of faveoli; (3) or develops normally. A right pulmonary artery always develops, but the left develops only if the left lung develops. No pulmonary artery develops in relation to the tracheal lung. We conclude that heterochrony in lung bud development contributes to lung asymmetry in several snake taxa. Secondly, the development of the pulmonary arteries is asymmetric at early stages, possibly because the splanchnic plexus fails to develop when the left lung is reduced. Finally, some changes in the topography of the pulmonary arteries are consequent on ontogenetic displacement of the heart down the body. Our findings show that the left-right asymmetry in the cardiorespiratory system of snakes is expressed early in development and may become phenotypically expressed through heterochronic shifts in growth, and changes in axial relations of organs and vessels. We propose a step-wise model for reduction of the left lung during snake evolution.

  12. Moderate Aerobic Training Improves Cardiorespiratory Parameters in Elastase-Induced Emphysema

    Science.gov (United States)

    Henriques, Isabela; Lopes-Pacheco, Miquéias; Padilha, Gisele A.; Marques, Patrícia S.; Magalhães, Raquel F.; Antunes, Mariana A.; Morales, Marcelo M.; Rocha, Nazareth N.; Silva, Pedro L.; Xisto, Débora G.; Rocco, Patricia R. M.

    2016-01-01

    Aim: We investigated the therapeutic effects of aerobic training on lung mechanics, inflammation, morphometry and biological markers associated with inflammation, and endothelial cell damage, as well as cardiac function in a model of elastase-induced emphysema. Methods: Eighty-four BALB/c mice were randomly allocated to receive saline (control, C) or 0.1 IU porcine pancreatic elastase (emphysema, ELA) intratracheally once weekly for 4 weeks. After the end of administration period, once cardiorespiratory impairment associated with emphysema was confirmed, each group was further randomized into sedentary (S) and trained (T) subgroups. Trained mice ran on a motorized treadmill, at moderate intensity, 30 min/day, 3 times/week for 4 weeks. Results: Four weeks after the first instillation, ELA animals, compared to C, showed: (1) reduced static lung elastance (Est,L) and levels of vascular endothelial growth factor (VEGF) in lung tissue, (2) increased elastic and collagen fiber content, dynamic elastance (E, in vitro), alveolar hyperinflation, and levels of interleukin-1β and tumor necrosis factor (TNF)-α, and (3) increased right ventricular diastolic area (RVA). Four weeks after aerobic training, ELA-T group, compared to ELA-S, was associated with reduced lung hyperinflation, elastic and collagen fiber content, TNF-α levels, and RVA, as well as increased Est,L, E, and levels of VEGF. Conclusion: Four weeks of regular and moderate intensity aerobic training modulated lung inflammation and remodeling, thus improving pulmonary function, and reduced RVA and pulmonary arterial hypertension in this animal model of elastase-induced emphysema. PMID:27536247

  13. Moderate aerobic training improves cardiorespiratory parameters in elastase-induced emphysema

    Directory of Open Access Journals (Sweden)

    Isabela Henriques

    2016-08-01

    Full Text Available Aim: We investigated the therapeutic effects of aerobic training on lung mechanics, inflammation, morphometry and biological markers associated with inflammation and endothelial cell damage, as well as cardiac function in a model of elastase-induced emphysema. Methods: Eighty-four BALB/c mice were randomly allocated to receive saline (control, C or 0.1 IU porcine pancreatic elastase (emphysema, ELA intratracheally once weekly for 4 weeks. After the end of administration period, once cardiorespiratory impairment associated with emphysema was confirmed, each group was further randomized into sedentary (S and trained (T subgroups. Trained mice ran on a motorized treadmill, at moderate intensity, 30 min/day, 3 times/week for 4 weeks. Results: Four weeks after the first instillation, ELA animals, compared to C, showed: 1 reduced static lung elastance (Est,L and levels of vascular endothelial growth factor (VEGF in lung tissue, 2 increased elastic and collagen fiber content, dynamic elastance (E, in vitro, alveolar hyperinflation, and levels of interleukin-1β and tumor necrosis factor (TNF-α, and 3 increased right ventricular diastolic area (RVA. Four weeks after aerobic training, ELA-T group, compared to ELA-S, was associated with reduced lung hyperinflation, elastic and collagen fiber content, TNF-α levels, and RVA, as well as increased Est,L, E, and levels of VEGF. Conclusion: Four weeks of regular and moderate intensity aerobic training modulated lung inflammation and remodeling, thus improving pulmonary function, and reduced RVA and pulmonary arterial hypertension in this animal model of elastase-induced emphysema.

  14. [Effects of high- and low-intensity training on cardiorespiratory system and serum lipids].

    Science.gov (United States)

    Yanagibori, R; Aoki, K; Suzuki, Y; Gunji, A

    1991-08-01

    The differences between the effects of high- and low-intensity exercise training on cardiorespiratory system and serum lipid levels were examined under conditions in which the total work load was same. Twenty-two healthy, untrained female students, aged 18 to 24 years, participated in the 8-week training experiment. Two training groups exercised on bicycle ergometers 4-5d/wk for 8 wk with high-intensity (H: 70% VO2 max 13 min/session; N = 8) or in low-intensity (L: 36% VO2 max 33 min/session; N = 8). The control group (C: N = 6) continued its sedentary life style. Data of 6 students (H: N = 2, L: N = 2, C: N = 2) were excluded from the analysis, because they did not carry out their duties. The results of this study were as follows; 1) Aerobic capacity increased in both training groups. 2) After training, both heart rates and oxygen uptake during submaximal work loads significantly decreased in group H, but only heart rates significantly decreased in group L. 3) Heart rates with a same oxygen-uptake load during submaximal work seemed to increase in group H, but significantly decreased in group L. 4) The mechanical efficiency during the submaximal work load significantly increased in group H, but not in group L. 5) DBP and MBP during the submaximal work load in group L significantly decreased compared with those before the training. SBP with a same oxygen-uptake load during submaximal work increased in group H, but decreased in group L. 6) Rate pressure products both at rest and during submaximal exercise decreased significantly in group L. 7) Serum lipid levels remained in all groups. These results suggested that when the amount of exercise is the same, low-intensity exercise training with 35% VO2 max was more effective to increase endurance capacity and was safer than high-intensity exercise training. PMID:1956126

  15. Functional mapping of the cardiorespiratory effects of dorsal and median raphe nuclei in the rat

    Directory of Open Access Journals (Sweden)

    R.M. Alvarenga

    2005-11-01

    Full Text Available The dorsal (DRN and median (MRN raphe nuclei are important sources of serotonergic innervation to the forebrain, projecting to sites involved in cardiovascular regulation. These nuclei have been mapped using electrical stimulation, which has the limitation of stimulating fibers of passage. The present study maps these areas with chemical stimulation, investigating their influence on cardiorespiratory parameters. Urethane-anesthetized (1.2 g/kg, iv male Wistar rats (280-300 g were instrumented for pulsatile and mean blood pressure (MBP, heart rate, renal nerve activity, and respiratory frequency recordings. Microinjections of L-glutamate (0.18 M, 50-100 nl with 1% Pontamine Sky Blue were performed within the DRN or the MRN with glass micropipettes. At the end of the experiments the sites of microinjection were identified. The majority of sites within the MRN (86.1% and DRN (85.4% evoked pressor responses when stimulated (DRN: deltaMBP = +14.7 ± 1.2; MRN: deltaMBP = +13.6 ± 1.3 mmHg. The changes in renal nerve activity and respiratory rate caused by L-glutamate were +45 ± 11 and +42 ± 9% (DRN; P < 0.05%, +40 ± 10 and +29 ± 7% (MRN, P < 0.05, respectively. No significant changes were observed in saline-microinjected animals. This study shows that: a the blood pressure increases previously observed by electrical stimulation within the raphe are due to activation of local neurons, b this pressor effect is due to sympathoexcitation because the stimulation increased renal sympathetic activity but did not produce tachycardia, and c the stimulation of cell bodies in these nuclei also increases the respiratory rate.

  16. Effects of sedation during upper gastrointestinal endoscopy on endocrine response and cardiorespiratory function

    Directory of Open Access Journals (Sweden)

    G. Yetkin

    2007-12-01

    Full Text Available Upper gastrointestinal endoscopy is often accompanied by tachycardia which is known to be an important pathogenic factor in the development of myocardial ischemia. The pathogenesis of tachycardia is unknown but the condition is thought to be due to the endocrine response to endoscopy. The purpose of the present study was to investigate the effects of sedation on the endocrine response and cardiorespiratory function. Forty patients scheduled for diagnostic upper gastrointestinal endoscopy were randomized into 2 groups. While the patients in the first group did not receive sedation during upper gastrointestinal endoscopy, the patients in the second group were sedated with intravenous midazolam at the dose of 5 mg for those under 65 years or 2.5 mg for those aged 65 years or more. Midazolam was administered by slow infusion. In both groups, blood pressure, ECG tracing, heart rate, and peripheral oxygen saturation (SpO2 were monitored during endoscopy. In addition, blood samples for the determination of cortisol, glucose and C-reactive protein levels were obtained from patients in both groups prior to and following endoscopy. Heart rate and systolic arterial pressure changes were within normal limits in both groups. Comparison of the two groups regarding the values of these two parameters did not reveal a significant difference, while a statistically significant reduction in SpO2 was found in the sedation group. No significant differences in serum cortisol, glucose or C-reactive protein levels were observed between the sedated and non-sedated group. Sedation with midazolam did not reduce the endocrine response and the tachycardia developing during upper gastrointestinal endoscopy, but increased the reduction in SpO2.

  17. SE-FIT

    Science.gov (United States)

    Chen, Yongkang; Weislogel, Mark; Schaeffer, Ben; Semerjian, Ben; Yang, Lihong; Zimmerli, Gregory

    2012-01-01

    The mathematical theory of capillary surfaces has developed steadily over the centuries, but it was not until the last few decades that new technologies have put a more urgent demand on a substantially more qualitative and quantitative understanding of phenomena relating to capillarity in general. So far, the new theory development successfully predicts the behavior of capillary surfaces for special cases. However, an efficient quantitative mathematical prediction of capillary phenomena related to the shape and stability of geometrically complex equilibrium capillary surfaces remains a significant challenge. As one of many numerical tools, the open-source Surface Evolver (SE) algorithm has played an important role over the last two decades. The current effort was undertaken to provide a front-end to enhance the accessibility of SE for the purposes of design and analysis. Like SE, the new code is open-source and will remain under development for the foreseeable future. The ultimate goal of the current Surface Evolver Fluid Interface Tool (SEFIT) development is to build a fully integrated front-end with a set of graphical user interface (GUI) elements. Such a front-end enables the access to functionalities that are developed along with the GUIs to deal with pre-processing, convergence computation operation, and post-processing. In other words, SE-FIT is not just a GUI front-end, but an integrated environment that can perform sophisticated computational tasks, e.g. importing industry standard file formats and employing parameter sweep functions, which are both lacking in SE, and require minimal interaction by the user. These functions are created using a mixture of Visual Basic and the SE script language. These form the foundation for a high-performance front-end that substantially simplifies use without sacrificing the proven capabilities of SE. The real power of SE-FIT lies in its automated pre-processing, pre-defined geometries, convergence computation operation

  18. Automatic reconstruction of skeletal structures from TLS forest scenes

    Science.gov (United States)

    Schilling, A.; Maas, H.-G.

    2014-05-01

    Detailed information about 3D forest structure is vital in forest science for analyzing the spatio-temporal development of plants as well as precise harvest forecasting in forest industry. Up to now, the majority of methods focus on complete structural reconstruction of trees from multiple scans, which might not be a suitable starting point with respect to modeling forest scenes over larger areas. For this reason, we propose a strategy to obtain skeletal structures of trees from single scans following a divide-and-conquer approach well-known from computer science. First, we split the range image into components representing surface patches and trace each component's boundary, which is essential for our skeleton retrieval method. Therefore, we propose an extension to standard boundary tracing that takes a component's interior depth discontinuities into account. Second, each component is processed separately: A 2D skeleton is obtained via the Voronoi Diagram and refined. Subsequently, a component is segmented into subsets of points depending on their proximity to skeleton nodes. Afterwards, the skeleton is split into paths and a Principal Curve is computed from each path's point cluster in order to retrieve the component shape as a set of 3D polygonal lines. Our method retrieves the intricate branching structure of components representing tree crown parts reliably and efficiently. The results are fitting with respect to a visual inspection. At present, results are fragments of tree skeletons, but it opens an attractive perspective to complete tree skeletons from skeletal parts, which we currently regard as future work.

  19. Physical activity, physical fitness and the effect of exercise training interventions in lymphoma patients: a systematic review.

    Science.gov (United States)

    Vermaete, Nele; Wolter, Pascal; Verhoef, Gregor; Gosselink, Rik

    2013-08-01

    Fatigue is one of the most common and most distressing problems in lymphoma patients. A vicious circle is presumed between fatigue, physical activity and physical fitness. It is plausible that an exercise training program would be effective in reducing fatigue, by breaking this vicious circle. The purposes of this review are to provide an overview of the literature on physical activity and physical fitness in lymphoma patients before, during and after anticancer treatment, and to summarise the literature on exercise training interventions in lymphoma patients. We conducted a search for studies reporting on physical activity, physical fitness or the effect of exercise training in lymphoma patients. A total of 13 articles were selected. Due to a small number of articles and methodological issues, it was not possible to make final conclusions. The results indicated that 21 % to 29 % of lymphoma survivors meet the American College of Sports Medicine public health guidelines for physical activity. Maximal exercise capacity was decreased before treatment, especially in patients with advanced disease, and was close to normal during and/or after treatment. Lower levels of physical activity as well as lower physical fitness seemed to be associated with more symptoms of fatigue. Aerobic exercise training interventions seemed to be feasible and safe and had positive effects on cardiorespiratory fitness, fatigue and self-reported physical functioning. Further research is needed to examine physical activity and physical fitness in a longitudinal, objective way in large samples and to examine the effect of exercise training in lymphoma patients.

  20. A systematic review to determine reliability and usefulness of the field-based test batteries for the assessment of physical fitness in adolescents – The ASSO Project

    Directory of Open Access Journals (Sweden)

    Antonino Bianco

    2015-06-01

    Full Text Available The aim of the present review is to investigate the main field-based tests, used alone or included in sport or fitness batteries, for the assessment of health- and skill-related physical fitness components in adolescents. Different scientific databases were searched through using the selected key words related to physical fitness and its components for adolescence. The search focused on original articles and reviews/meta-analyses using valid, reproducible and feasible tests that fit within the school environment. A total of 100 scientific manuscripts were included in the qualitative synthesis. The present systematic review pointed out 5 fitness tests that well adapt to the evaluation of the components of physical fitness of adolescents within a school environment: the 20 m shuttle run test for cardio-respiratory endurance; the handgrip strength test for upper body maximal strength; the standing broad jump test for lower body maximal strength; the sit-up test to exhaustion for muscular endurance and the 4×10 m shuttle run test for speed, agility and coordination. These fitness tests have been finally selected and incorporated into the Adolescents and Surveillance System for the Obesity prevention – Fitness Test Battery (ASSO-FTB, and will be adopted within the ASSO Project for evaluation purposes. This instrument could be also provided to teachers and people working in schools in order to assess physical fitness of adolescents over time and prevent obesity and related diseases.

  1. A systematic review to determine reliability and usefulness of the field-based test batteries for the assessment of physical fitness in adolescents - The ASSO Project.

    Science.gov (United States)

    Bianco, Antonino; Jemni, Moném; Thomas, Ewan; Patti, Antonino; Paoli, Antonio; Ramos Roque, Joana; Palma, Antonio; Mammina, Caterina; Tabacchi, Garden

    2015-01-01

    The aim of the present review is to investigate the main field-based tests, used alone or included in sport or fitness batteries, for the assessment of health- and skill-related physical fitness components in adolescents. Different scientific databases were searched through using the selected key words related to physical fitness and its components for adolescence. The search focused on original articles and reviews/meta-analyses using valid, reproducible and feasible tests that fit within the school environment. A total of 100 scientific manuscripts were included in the qualitative synthesis. The present systematic review pointed out 5 fitness tests that well adapt to the evaluation of the components of physical fitness of adolescents within a school environment: the 20 m shuttle run test for cardio-respiratory endurance; the handgrip strength test for upper body maximal strength; the standing broad jump test for lower body maximal strength; the sit-up test to exhaustion for muscular endurance and the 4×10 m shuttle run test for speed, agility and coordination. These fitness tests have been finally selected and incorporated into the Adolescents and Surveillance System for the Obesity prevention - Fitness Test Battery (ASSO-FTB), and will be adopted within the ASSO Project for evaluation purposes. This instrument could be also provided to teachers and people working in schools in order to assess physical fitness of adolescents over time and prevent obesity and related diseases. PMID:26190724

  2. Skeletal muscle glucose uptake during exercise

    DEFF Research Database (Denmark)

    Rose, Adam John; Richter, Erik A.

    2005-01-01

    The increase in skeletal muscle glucose uptake during exercise results from a coordinated increase in rates of glucose delivery (higher capillary perfusion), surface membrane glucose transport, and intracellular substrate flux through glycolysis. The mechanism behind the movement of GLUT4...

  3. Pathogenesis of Insulin Resistance in Skeletal Muscle

    Directory of Open Access Journals (Sweden)

    Muhammad A. Abdul-Ghani

    2010-01-01

    Full Text Available Insulin resistance in skeletal muscle is manifested by decreased insulin-stimulated glucose uptake and results from impaired insulin signaling and multiple post-receptor intracellular defects including impaired glucose transport, glucose phosphorylation, and reduced glucose oxidation and glycogen synthesis. Insulin resistance is a core defect in type 2 diabetes, it is also associated with obesity and the metabolic syndrome. Dysregulation of fatty acid metabolism plays a pivotal role in the pathogenesis of insulin resistance in skeletal muscle. Recent studies have reported a mitochondrial defect in oxidative phosphorylation in skeletal muscle in variety of insulin resistant states. In this review, we summarize the cellular and molecular defects that contribute to the development of insulin resistance in skeletal muscle.

  4. Inflammation induced loss of skeletal muscle.

    Science.gov (United States)

    Londhe, Priya; Guttridge, Denis C

    2015-11-01

    Inflammation is an important contributor to the pathology of diseases implicated in skeletal muscle dysfunction. A number of diseases and disorders including inflammatory myopathies and Chronic Obstructive Pulmonary Disorder (COPD) are characterized by chronic inflammation or elevation of the inflammatory mediators. While these disease states exhibit different pathologies, all have in common the loss of skeletal muscle mass and a deregulated skeletal muscle physiology. Pro-inflammatory cytokines are key contributors to chronic inflammation found in many of these diseases. This section of the review focuses on some of the known inflammatory disorders like COPD, Rheumatoid Arthritis (RA) and inflammatory myopathies that display skeletal muscle atrophy and also provides the reader an overview of the mediators of inflammation, their signaling pathways, and mechanisms of action. This article is part of a Special Issue entitled "Muscle Bone Interactions".

  5. Exercise Promotes Healthy Aging of Skeletal Muscle

    DEFF Research Database (Denmark)

    Cartee, Gregory D; Hepple, Russell T; Bamman, Marcas M;

    2016-01-01

    Primary aging is the progressive and inevitable process of bodily deterioration during adulthood. In skeletal muscle, primary aging causes defective mitochondrial energetics and reduced muscle mass. Secondary aging refers to additional deleterious structural and functional age-related changes cau...

  6. How to measure inclusive fitness.

    Science.gov (United States)

    Creel, S

    1990-09-22

    Although inclusive fitness (Hamilton 1964) is regarded as the basic currency of natural selection, difficulty in applying inclusive fitness theory to field studies persists, a quarter-century after its introduction (Grafen 1982, 1984; Brown 1987). For instance, strict application of the original (and currently accepted) definition of inclusive fitness predicts that no one should ever attempt to breed among obligately cooperative breeders. Much of this confusion may have arisen because Hamilton's (1964) original verbal definition of inclusive fitness was not in complete accord with his justifying model. By re-examining Hamilton's original model, a modified verbal definition of inclusive fitness can be justified. PMID:1979447

  7. [Regeneration capacity of skeletal muscle].

    Science.gov (United States)

    Wernig, A

    2003-07-01

    The organotypic stem cell of skeletal muscle has previously been known as satellite cell. They allow muscle fiber growth during ontogenesis, enable fiber hypertrophy and are responsible for the very efficient repair of muscle fibers. This efficient apparatus is to some degree counterbalanced by an enormous use of the satellite cell pool: fiber atrophy probably is accompanied by loss of myonuclei such that every reversal of atrophy is bound to use new myonuclei i.e. satellite cells. How often in life does this occur? Hard to say. Moreover, the potent repair capacity is challenged by an unexpected vulnerability of skeletal muscle fibers: Passive stretching of contracted muscles may cause multiple "microdamage," disruption of contractile elements or tiny areas of true necrosis (focal necrosis). How often does this happen? Well, for many of us at least once per year when we go up and down mountains during vacation time, followed by sour muscles. Others may decide to change his/her (locomotor) behaviour by severe onset of jogging; it may happen that they suffer kidney failure on Monday due to muscle microdamage and the transfer of myoproteins into the serum over weekend. Also 20 minutes of stepping up and down something like a chair will do: There is a remarkable increase in kreatin kinase and other muscle derived proteins which lasts for days and is bound to reflect some muscle damage. How about sportsmen and worker who repeatedly use their muscles in such a way? We don't have answers yet to most of these questions, but considerable amount of information has been collected over the last years both in animal and--less--in human. What is common in all cases of growth and repair is the proliferation of the satellite cells and their consequent incorporation and fusion with the parent fiber. This way focal damage is repaired often without visible reminders. We would run out of satellite cells were they not stem cells: After division one daughter remains a satellite cell

  8. Independent and Combined Association of Muscle Strength and Cardiorespiratory Fitness in Youth With Insulin Resistance and β-Cell Function in Young Adulthood

    DEFF Research Database (Denmark)

    Grøntved, Anders; Ried-Larsen, Mathias; Ekelund, Ulf;

    2013-01-01

    ergometer test. Insulin resistance (homeostasis model assessment of insulin resistance [HOMA-IR]) and β-cell function (homeostasis model assessment of β-cell function [HOMA-B]) were estimated from fasting serum insulin and glucose that were obtained in youth and at follow-up in young adulthood.......RESULTSFor each 1-SD difference in isometric muscle strength (0.16 N/kg) in youth, fasting insulin, HOMA-IR, and HOMA-B in young adulthood changed with -11.3% (95% CI, -17.0 to -5.2), -12.2% (-18.2 to -5.7), and -8.9% (-14.4 to -3.0), respectively, in young adulthood after adjustment for CRF and personal...... lifestyle and demographic factors. Results for CRF were very similar in magnitude, and the magnitude of associations for both exposures was unchanged with additional adjustment for general or abdominal adiposity in youth. Combined associations of muscle strength and CRF with fasting insulin, HOMA...

  9. Increased skeletal muscle capillarization enhances insulin sensitivity.

    Science.gov (United States)

    Akerstrom, Thorbjorn; Laub, Lasse; Vedel, Kenneth; Brand, Christian Lehn; Pedersen, Bente Klarlund; Lindqvist, Anna Kaufmann; Wojtaszewski, Jørgen F P; Hellsten, Ylva

    2014-12-15

    Increased skeletal muscle capillarization is associated with improved glucose tolerance and insulin sensitivity. However, a possible causal relationship has not previously been identified. Therefore, we investigated whether increased skeletal muscle capillarization increases insulin sensitivity. Skeletal muscle-specific angiogenesis was induced by adding the α1-adrenergic receptor antagonist prazosin to the drinking water of Sprague-Dawley rats (n = 33), whereas 34 rats served as controls. Insulin sensitivity was measured ≥40 h after termination of the 3-wk prazosin treatment, which ensured that prazosin was cleared from the blood stream. Whole body insulin sensitivity was measured in conscious, unrestrained rats by hyperinsulinemic euglycemic clamp. Tissue-specific insulin sensitivity was assessed by administration of 2-deoxy-[(3)H]glucose during the plateau phase of the clamp. Whole body insulin sensitivity increased by ∼24%, and insulin-stimulated skeletal muscle 2-deoxy-[(3)H]glucose disposal increased by ∼30% concomitant with an ∼20% increase in skeletal muscle capillarization. Adipose tissue insulin sensitivity was not affected by the treatment. Insulin-stimulated muscle glucose uptake was enhanced independent of improvements in skeletal muscle insulin signaling to glucose uptake and glycogen synthesis, suggesting that the improvement in insulin-stimulated muscle glucose uptake could be due to improved diffusion conditions for glucose in the muscle. The prazosin treatment did not affect the rats on any other parameters measured. We conclude that an increase in skeletal muscle capillarization is associated with increased insulin sensitivity. These data point toward the importance of increasing skeletal muscle capillarization for prevention or treatment of type 2 diabetes. PMID:25352432

  10. Skeletal Aging and Osteoporosis Biomechanics and Mechanobiology

    CERN Document Server

    2013-01-01

    The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis.

  11. Multifocal skeletal tuberculosis: A case report

    OpenAIRE

    Zhang, Liang; Wang, Jingcheng; Feng, Xinmin; Tao, Yuping; Yang, Jiandong; ZHANG, SHENFEI; Cai, Jun

    2016-01-01

    Tuberculosis (TB) of the musculoskeletal system is a rare clinical condition. Multifocal bone involvement is extremely rare and difficult to recognize. Thus, due to the diverse and atypical clinical manifestations of multifocal skeletal TB, the disease is easy to misdiagnose. In the present study, a rare case of atypical disseminated multifocal skeletal TB was reported, which exhibited uncommon findings in radiological images that were more suggestive of a hematological malignancy or metastat...

  12. Redox control of skeletal muscle atrophy.

    Science.gov (United States)

    Powers, Scott K; Morton, Aaron B; Ahn, Bumsoo; Smuder, Ashley J

    2016-09-01

    Skeletal muscles comprise the largest organ system in the body and play an essential role in body movement, breathing, and glucose homeostasis. Skeletal muscle is also an important endocrine organ that contributes to the health of numerous body organs. Therefore, maintaining healthy skeletal muscles is important to support overall health of the body. Prolonged periods of muscle inactivity (e.g., bed rest or limb immobilization) or chronic inflammatory diseases (i.e., cancer, kidney failure, etc.) result in skeletal muscle atrophy. An excessive loss of muscle mass is associated with a poor prognosis in several diseases and significant muscle weakness impairs the quality of life. The skeletal muscle atrophy that occurs in response to inflammatory diseases or prolonged inactivity is often associated with both oxidative and nitrosative stress. In this report, we critically review the experimental evidence that provides support for a causative link between oxidants and muscle atrophy. More specifically, this review will debate the sources of oxidant production in skeletal muscle undergoing atrophy as well as provide a detailed discussion on how reactive oxygen species and reactive nitrogen species modulate the signaling pathways that regulate both protein synthesis and protein breakdown. PMID:26912035

  13. Redox control of skeletal muscle atrophy.

    Science.gov (United States)

    Powers, Scott K; Morton, Aaron B; Ahn, Bumsoo; Smuder, Ashley J

    2016-09-01

    Skeletal muscles comprise the largest organ system in the body and play an essential role in body movement, breathing, and glucose homeostasis. Skeletal muscle is also an important endocrine organ that contributes to the health of numerous body organs. Therefore, maintaining healthy skeletal muscles is important to support overall health of the body. Prolonged periods of muscle inactivity (e.g., bed rest or limb immobilization) or chronic inflammatory diseases (i.e., cancer, kidney failure, etc.) result in skeletal muscle atrophy. An excessive loss of muscle mass is associated with a poor prognosis in several diseases and significant muscle weakness impairs the quality of life. The skeletal muscle atrophy that occurs in response to inflammatory diseases or prolonged inactivity is often associated with both oxidative and nitrosative stress. In this report, we critically review the experimental evidence that provides support for a causative link between oxidants and muscle atrophy. More specifically, this review will debate the sources of oxidant production in skeletal muscle undergoing atrophy as well as provide a detailed discussion on how reactive oxygen species and reactive nitrogen species modulate the signaling pathways that regulate both protein synthesis and protein breakdown.

  14. Fitness in fluctuating environments

    Science.gov (United States)

    Tanase Nicola, Sorin; Nemenman, Ilya

    2011-03-01

    Often environments change faster than the time needed to evolve optimal phenotypes through cycles of mutation and selection. We focus on this case, but assume that environmental oscillations are slower than an individual's lifetime. This is relevant, for example, for bacterial populations confronted with daily environmental changes. We analyze a resource-limited competition between a mutant phenotype and the ancestor. Environmental dynamics is represented by periodically varying, off-phase parameters of the corresponding Lotka-Volterra model. For the very slow dynamics (but still faster than the fixation time scale) the strength and the sign of selection are functions of the birth/death rates averaged over all of the environmental states and independent of the period of the fluctuations. For faster fluctuations, selection depends on the particular sequence of the successive environmental states. In particular, a time reversal of the environmental dynamics can change the sign of the selection. We conclude that the fittest phenotype in a changing environment can be very different from both the optimal phenotype in the average environment, and the phenotype with the largest average fitness.

  15. Locomotor muscle fatigue increases cardiorespiratory responses and reduces performance during intense cycling exercise independently from metabolic stress.

    Science.gov (United States)

    Marcora, Samuele M; Bosio, Andrea; de Morree, Helma M

    2008-03-01

    Locomotor muscle fatigue, defined as an exercise-induced reduction in maximal voluntary force, occurs during prolonged exercise, but its effects on cardiorespiratory responses and exercise performance are unknown. In this investigation, a significant reduction in locomotor muscle force (-18%, P drop-jumps protocol consisting of one jump every 20 s from a 40-cm-high platform. The effect of this treatment on time to exhaustion during high-intensity constant-power cycling was measured in study 1 (n = 10). In study 2 (n = 14), test duration (871 +/- 280 s) was matched between fatigue and control condition (rest). In study 1, locomotor muscle fatigue caused a significant curtailment in time to exhaustion (636 +/- 278 s) compared with control (750 +/- 281 s) (P = 0.003) and increased cardiac output. Breathing frequency was significantly higher in the fatigue condition in both studies despite similar oxygen consumption and blood lactate accumulation. In study 2, high-intensity cycling did not induce further fatigue to eccentrically-fatigued locomotor muscles. In both studies, there was a significant increase in heart rate in the fatigue condition, and perceived exertion was significantly increased in study 2 compared with control. These results suggest that locomotor muscle fatigue has a significant influence on cardiorespiratory responses and exercise performance during high-intensity cycling independently from metabolic stress. These effects seem to be mediated by the increased central motor command and perception of effort required to exercise with weaker locomotor muscles. PMID:18184760

  16. A novel land use approach for assessment of human health: The relationship between urban structure types and cardiorespiratory disease risk.

    Science.gov (United States)

    Réquia Júnior, Weeberb João; Roig, Henrique Llacer; Koutrakis, Petros

    2015-12-01

    Extensive evidence shows that in addition to lifestyle factors, environmental aspects are an important risk factor for human health. Numerous approaches have been used to estimate the relationship between environment and health. For example, the urban characteristics, especially the types of land use, are considered a potential proxy indicator to evaluate risk of disease. Although several studies have used land use variables to assess human health, none of them has used the concept of Urban Morphology by Urban Structure Types (USTs) as indicators of land use. The aim of this study was to assess the relationship between USTs and cardiorespiratory disease risks in the Federal District, Brazil. Toward this end, we used a quantile regression model to estimate risk. We used 21 types of UST. Income and population density were used as covariates in our sensitivity analysis. Our analysis showed an association between cardiorespiratory diseases risk and 10 UST variables (1 related to rural area, 6 related to residential area, 1 recreational area, 1 public area and 1 commercial area). Our findings suggest that the conventional land use method may be missing important information about the effect of land use on human health. The use of USTs can be an approach to complement the conventional method. This should be of interest to policy makers in order to enhance public health policies and to create future strategies in terms of urban planning, land use and environmental health.

  17. The influence of aerobic fitness status on ventilatory efficiency in patients with coronary artery disease

    Directory of Open Access Journals (Sweden)

    Danilo M.L. Prado

    2015-01-01

    Full Text Available OBJECTIVE: To test the hypotheses that 1 coronary artery disease patients with lower aerobic fitness exhibit a lower ventilatory efficiency and 2 coronary artery disease patients with lower initial aerobic fitness exhibit greater improvements in ventilatory efficiency with aerobic exercise training. METHOD: A total of 123 patients (61.0±0.7 years with coronary artery disease were divided according to aerobic fitness status into 3 groups: group 1 (n = 34, peak VO217.5 and 24.5 ml/kg/min. All patients performed a cardiorespiratory exercise test on a treadmill. Ventilatory efficiency was determined by the lowest VE/VCO2 ratio observed. The exercise training program comprised moderate-intensity aerobic exercise performed 3 times per week for 3 months. Clinicaltrials.gov: NCT02106533 RESULTS: Before intervention, group 1 exhibited both lower peak VO2 and lower ventilatory efficiency compared with the other 2 groups (p<0.05. After the exercise training program, group 1 exhibited greater improvements in aerobic fitness and ventilatory efficiency compared with the 2 other groups (group 1: ▵ = -2.5±0.5 units; group 2: ▵ = -0.8±0.3 units; and group 3: ▵ = -1.4±0.6 units, respectively; p<0.05. CONCLUSIONS: Coronary artery disease patients with lower aerobic fitness status exhibited lower ventilatory efficiency during a graded exercise test. In addition, after 3 months of aerobic exercise training, only the patients with initially lower levels of aerobic fitness exhibited greater improvements in ventilatory efficiency.

  18. The effects of 12 weeks of step aerobics training on functional fitness of elderly women.

    Science.gov (United States)

    Hallage, Tatiane; Krause, Maressa P; Haile, Luke; Miculis, Cristiane P; Nagle, Elizabeth F; Reis, Rodrigo S; Da Silva, Sergio G

    2010-08-01

    The purpose of this study was to determine the effects of 12 weeks of step aerobics (SA) training on the functional fitness of apparently healthy older women. Thirteen previously sedentary elderly women (mean age 63.14 years) participated in this study. Subjects performed 3 training sessions per week for 30-60 minutes per session. All measurements were assessed at baseline, after 12 weeks of training (posttest), and after 1 month of detraining. Assessments included the evaluation of body mass index (BMI), waist circumference (WC), strength of the upper (arm-curl [AC] test) and lower body (30-second chair-stand test [CS]), dynamic balance and agility (8 foot up and go [8 ft]), flexibility (chair sit-and-reach [CSR]), and cardiorespiratory fitness (6-minute walk test [6MW]). Step aerobics significantly improved all functional fitness components except for BMI. The 12 weeks of SA promoted a large effect size in the following measurements: WC (d = 1.6); CSR (d = 1.51); CS (d = 1.49); AC (d = 1.41); 8 ft (d = 1.32); and 6MW (d = 1.06) (p < 0.05). These results indicate that 12 weeks of SA had a positive effect on the functional fitness components of these older women. Furthermore, these findings were confirmed by the reverse effect observed after 1 month of detraining, except for upper body strength (AC test). In conclusion, 12 weeks of SA training can promote improvements in the functional fitness of apparently healthy older women. Therefore, SA can be considered an effective exercise modality to prevent the loss of functional fitness and its associated consequences. PMID:20634751

  19. Cardiorespiratory responses to moderate exercise and determination of aerobic power in first year medical students

    OpenAIRE

    Subha Kavundapadi Chandrasekaran; Rajkumar Devaraj

    2016-01-01

    Background: Cardiovascular and metabolic disorder has become common in individuals leading a sedentary life. Exercise stress tests are carried out as part of the investigations for determining the individual fitness level. Aerobic power or VO2max which involves a full functional support from cardio respiratory and metabolic pathways is an appropriate test to study cardio pulmonary fitness. The main objective of the study is to find out the normal cardiopulmonary responses to exercise and thei...

  20. A Model of the Cardiorespiratory Response to Aerobic Exercise in Healthy and Heart Failure Conditions.

    Science.gov (United States)

    Fresiello, Libera; Meyns, Bart; Di Molfetta, Arianna; Ferrari, Gianfranco

    2016-01-01

    The physiological response to physical exercise is now recognized as an important tool which can aid the diagnosis and treatment of cardiovascular diseases. This is due to the fact that several mechanisms are needed to accommodate a higher cardiac output and a higher oxygen delivery to tissues. The aim of the present work is to provide a fully closed loop cardiorespiratory simulator reproducing the main physiological mechanisms which arise during aerobic exercise. The simulator also provides a representation of the impairments of these mechanisms in heart failure condition and their effect on limiting exercise capacity. The simulator consists of a cardiovascular model including the left and right heart, pulmonary and systemic circulations. This latter is split into exercising and non-exercising regions and is controlled by the baroreflex and metabolic mechanisms. In addition, the simulator includes a respiratory model reproducing the gas exchange in lungs and tissues, the ventilation control and the effects of its mechanics on the cardiovascular system. The simulator was tested and compared to the data in the literature at three different workloads whilst cycling (25, 49 and 73 watts). The results show that the simulator is able to reproduce the response to exercise in terms of: heart rate (from 67 to 134 bpm), cardiac output (from 5.3 to 10.2 l/min), leg blood flow (from 0.7 to 3.0 l/min), peripheral resistance (from 0.9 to 0.5 mmHg/(cm(3)/s)), central arteriovenous oxygen difference (from 4.5 to 10.8 ml/dl) and ventilation (6.1-25.5 l/min). The simulator was further adapted to reproduce the main impairments observed in heart failure condition, such as reduced sensitivity of baroreflex and metabolic controls, lower perfusion to the exercising regions (from 0.6 to 1.4 l/min) and hyperventilation (from 9.2 to 40.2 l/min). The simulator we developed is a useful tool for the description of the basic physiological mechanisms operating during exercise. It can reproduce

  1. Impact of acute exposure to air pollution on the cardiorespiratory performance of military firemen

    Directory of Open Access Journals (Sweden)

    R.S. Oliveira

    2006-12-01

    Full Text Available The objective of the present study was to determine the impact of acute short-term exposure to air pollution on the cardiorespiratory performance of military fireman living and working in the city of Guarujá, São Paulo, Brazil. Twenty-five healthy non-smoking firemen aged 24 to 45 years had about 1 h of exposure to low and high levels of air pollution. The tests consisted of two phases: phase A, in Bertioga, a town with low levels of air pollution, and phase B, in Cubatão, a polluted town, with a 7-day interval between phases. The volunteers remained in the cities (Bertioga/Cubatão only for the time required to perform the tests. Cumulative load 10 ± 2 min-long exertion tests were performed on a treadmill, consisting of a 2-min stage at a load of 7 km/h, followed by increasing exertion of 1 km h-1 min-1 until the maximum individual limit. There were statistically significant differences (P < 0.05 in anaerobic threshold (AT between Cubatão (35.04 ± 4.91 mL kg-1 min-1 and Bertioga (36.98 ± 5.62 mL kg-1 min-1; P = 0.01, in the heart rate at AT (AT HR; Cubatão 152.08 ± 14.86 bpm, Bertioga 157.44 ± 13.64 bpm; P = 0.001, and in percent maximal oxygen consumption at AT (AT%VO2max; Cubatão 64.56 ± 6.55%, Bertioga 67.40 ± 5.35%; P = 0.03. However, there were no differences in VO2max, maximal heart rate or velocity at AT (ATvel observed in firemen between towns. The acute exposure to pollutants in Cubatão, SP, caused a significant reduction in the performance at submaximal levels of physical exertion.

  2. Fitness Landscapes of Functional RNAs

    Directory of Open Access Journals (Sweden)

    Ádám Kun

    2015-08-01

    Full Text Available The notion of fitness landscapes, a map between genotype and fitness, was proposed more than 80 years ago. For most of this time data was only available for a few alleles, and thus we had only a restricted view of the whole fitness landscape. Recently, advances in genetics and molecular biology allow a more detailed view of them. Here we review experimental and theoretical studies of fitness landscapes of functional RNAs, especially aptamers and ribozymes. We find that RNA structures can be divided into critical structures, connecting structures, neutral structures and forbidden structures. Such characterisation, coupled with theoretical sequence-to-structure predictions, allows us to construct the whole fitness landscape. Fitness landscapes then can be used to study evolution, and in our case the development of the RNA world.

  3. Reeling of tight fit pipe

    OpenAIRE

    Focke, E.S.

    2007-01-01

    If it would be possible to install Tight Fit Pipe by means of reeling, it would be an attractive new option for the exploitation of offshore oil and gas fields containing corrosive hydrocarbons. Tight Fit Pipe is a mechanically bonded double walled pipe where a corrosion resistant alloy liner pipe is mechanically fitted inside a carbon steel outer pipe through a thermo-hydraulic manufacturing process. Reeling is a fast method of offshore pipeline installation where a pipe is spooled on a reel...

  4. Segmentation of branching vascular structures using adaptive subdivision surface fitting

    Science.gov (United States)

    Kitslaar, Pieter H.; van't Klooster, Ronald; Staring, Marius; Lelieveldt, Boudewijn P. F.; van der Geest, Rob J.

    2015-03-01

    This paper describes a novel method for segmentation and modeling of branching vessel structures in medical images using adaptive subdivision surfaces fitting. The method starts with a rough initial skeleton model of the vessel structure. A coarse triangular control mesh consisting of hexagonal rings and dedicated bifurcation elements is constructed from this skeleton. Special attention is paid to ensure a topological sound control mesh is created around the bifurcation areas. Then, a smooth tubular surface is obtained from this coarse mesh using a standard subdivision scheme. This subdivision surface is iteratively fitted to the image. During the fitting, the target update locations of the subdivision surface are obtained using a scanline search along the surface normals, finding the maximum gradient magnitude (of the imaging data). In addition to this surface fitting framework, we propose an adaptive mesh refinement scheme. In this step the coarse control mesh topology is updated based on the current segmentation result, enabling adaptation to varying vessel lumen diameters. This enhances the robustness and flexibility of the method and reduces the amount of prior knowledge needed to create the initial skeletal model. The method was applied to publicly available CTA data from the Carotid Bifurcation Algorithm Evaluation Framework resulting in an average dice index of 89.2% with the ground truth. Application of the method to the complex vascular structure of a coronary artery tree in CTA and to MRI images were performed to show the versatility and flexibility of the proposed framework.

  5. VPFIT: Voigt profile fitting program

    Science.gov (United States)

    Carswell, R. F.; Webb, J. K.

    2014-08-01

    The VPFIT program fits multiple Voigt profiles (convolved with the instrument profiles) to spectroscopic data that is in FITS or an ASCII file. It requires CFITSIO (ascl:1010.001) and PGPLOT (ascl:1103.002); the tarball includes RDGEN (ascl:1408.017), which can be used with VPFIT to set up the fits, fit the profiles, and examine the result in interactive mode for setting up initial guesses; vpguess (ascl:1408.016) can also be used to set up an initial file.

  6. How sex hormones promote skeletal muscle regeneration.

    Science.gov (United States)

    Velders, Martina; Diel, Patrick

    2013-11-01

    Skeletal muscle regeneration efficiency declines with age for both men and women. This decline impacts on functional capabilities in the elderly and limits their ability to engage in regular physical activity and to maintain independence. Aging is associated with a decline in sex hormone production. Therefore, elucidating the effects of sex hormone substitution on skeletal muscle homeostasis and regeneration after injury or disuse is highly relevant for the aging population, where sarcopenia affects more than 30 % of individuals over 60 years of age. While the anabolic effects of androgens are well known, the effects of estrogens on skeletal muscle anabolism have only been uncovered in recent times. Hence, the purpose of this review is to provide a mechanistic insight into the regulation of skeletal muscle regenerative processes by both androgens and estrogens. Animal studies using estrogen receptor (ER) antagonists and receptor subtype selective agonists have revealed that estrogens act through both genomic and non-genomic pathways to reduce leukocyte invasion and increase satellite cell numbers in regenerating skeletal muscle tissue. Although animal studies have been more conclusive than human studies in establishing a role for sex hormones in the attenuation of muscle damage, data from a number of recent well controlled human studies is presented to support the notion that hormonal therapies and exercise induce added positive effects on functional measures and lean tissue mass. Based on the fact that aging human skeletal muscle retains the ability to adapt to exercise with enhanced satellite cell activation, combining sex hormone therapies with exercise may induce additive effects on satellite cell accretion. There is evidence to suggest that there is a 'window of opportunity' after the onset of a hypogonadal state such as menopause, to initiate a hormonal therapy in order to achieve maximal benefits for skeletal muscle health. Novel receptor subtype selective

  7. How sex hormones promote skeletal muscle regeneration.

    Science.gov (United States)

    Velders, Martina; Diel, Patrick

    2013-11-01

    Skeletal muscle regeneration efficiency declines with age for both men and women. This decline impacts on functional capabilities in the elderly and limits their ability to engage in regular physical activity and to maintain independence. Aging is associated with a decline in sex hormone production. Therefore, elucidating the effects of sex hormone substitution on skeletal muscle homeostasis and regeneration after injury or disuse is highly relevant for the aging population, where sarcopenia affects more than 30 % of individuals over 60 years of age. While the anabolic effects of androgens are well known, the effects of estrogens on skeletal muscle anabolism have only been uncovered in recent times. Hence, the purpose of this review is to provide a mechanistic insight into the regulation of skeletal muscle regenerative processes by both androgens and estrogens. Animal studies using estrogen receptor (ER) antagonists and receptor subtype selective agonists have revealed that estrogens act through both genomic and non-genomic pathways to reduce leukocyte invasion and increase satellite cell numbers in regenerating skeletal muscle tissue. Although animal studies have been more conclusive than human studies in establishing a role for sex hormones in the attenuation of muscle damage, data from a number of recent well controlled human studies is presented to support the notion that hormonal therapies and exercise induce added positive effects on functional measures and lean tissue mass. Based on the fact that aging human skeletal muscle retains the ability to adapt to exercise with enhanced satellite cell activation, combining sex hormone therapies with exercise may induce additive effects on satellite cell accretion. There is evidence to suggest that there is a 'window of opportunity' after the onset of a hypogonadal state such as menopause, to initiate a hormonal therapy in order to achieve maximal benefits for skeletal muscle health. Novel receptor subtype selective

  8. Lip prints: The barcode of skeletal malocclusion

    Science.gov (United States)

    Raghav, Pradeep; Kumar, Naveen; Shingh, Shishir; Ahuja, N.K.; Ghalaut, Priyanka

    2013-01-01

    Introduction: In orthodontics, apart from essential diagnostic aids, there are so many soft tissue analyses in which lips are major part of concern. However, lip prints have never been used in orthodontics as diagnostic aid or forensic tool. Therefore, this study was designed to explore the possible association of lip prints with skeletal malocclusion. Materials and Methods: A sample of 114 subjects in the age group of 18-30 years, from North Indian adult population were selected on the basis of skeletal class I, class II and class III malocclusion, each comprising of 38 subjects with equal number of males and females. Lip prints of all the individuals were recorded and digital soft copies of lateral cephalograms were taken. Lip prints were compared between different skeletal malocclusions. Results: It was found that branched lip pattern was most common in North Indian adult population with no sexual dimorphism. The Z-test for proportion showed that the prevalence of vertical lip pattern was significantly higher in subjects having skeletal class III malocclusion. Conclusion: A definite co-relation of vertical lip patterns with skeletal class III malocclusion was revealed. PMID:24255559

  9. Lip prints: The barcode of skeletal malocclusion

    Directory of Open Access Journals (Sweden)

    Pradeep Raghav

    2013-01-01

    Full Text Available Introduction: In orthodontics, apart from essential diagnostic aids, there are so many soft tissue analyses in which lips are major part of concern. However, lip prints have never been used in orthodontics as diagnostic aid or forensic tool. Therefore, this study was designed to explore the possible association of lip prints with skeletal malocclusion. Materials and Methods: A sample of 114 subjects in the age group of 18-30 years, from North Indian adult population were selected on the basis of skeletal class I, class II and class III malocclusion, each comprising of 38 subjects with equal number of males and females. Lip prints of all the individuals were recorded and digital soft copies of lateral cephalograms were taken. Lip prints were compared between different skeletal malocclusions. Results: It was found that branched lip pattern was most common in North Indian adult population with no sexual dimorphism. The Z-test for proportion showed that the prevalence of vertical lip pattern was significantly higher in subjects having skeletal class III malocclusion. Conclusion: A definite co-relation of vertical lip patterns with skeletal class III malocclusion was revealed.

  10. Advances in Exercise, Fitness, and Performance Genomics in 2014

    Science.gov (United States)

    Loos, Ruth J. F.; Hagberg, James M.; Pérusse, Louis; Roth, Stephen M.; Sarzynski, Mark A.; Wolfarth, Bernd; Rankinen, Tuomo; Bouchard, Claude

    2015-01-01

    This is the annual review of the exercise genomics literature in which we report on the highest quality papers published in 2014. We identified a number of noteworthy papers across a number of fields. In 70 to 89 years old, only 19% of ACE II homozygotes exhibited significant improvement in gait speed in response to a year-long physical activity program compared to 30% of ACE D-allele carriers. New studies continue to support the notion that the genetic susceptibility to obesity, as evidenced by a genomic risk score (GRS; based on multiple SNPs), is attenuated by 40-50% in individuals who are physically active, compare to those who are sedentary. One study reported that the polygenic risk for hypertriglyceridemia was reduced by 30-40% in individuals with high cardiorespiratory fitness. One report showed that there was a significant interaction of a type 2 diabetes GRS with physical activity, with active individuals having the lowest risk of developing diabetes. The protective effect of was most pronounced in the low GRS tertile (HR=0.82). The interaction observed with the diabetes GRS appeared to be dependent on a genetic susceptibility to insulin resistance and not insulin secretion. A significant interaction between PPARα sequence variants and physical activity levels on cardiometabolic risk was observed, with higher activity levels associated with lower risk only in carriers of specific genotypes and haplotypes. The review concludes with a discussion of the importance of replication studies when very large population or intervention discovery studies are not feasible or are cost prohibitive. PMID:25706296

  11. Reeling of tight fit pipe

    NARCIS (Netherlands)

    Focke, E.S.

    2007-01-01

    If it would be possible to install Tight Fit Pipe by means of reeling, it would be an attractive new option for the exploitation of offshore oil and gas fields containing corrosive hydrocarbons. Tight Fit Pipe is a mechanically bonded double walled pipe where a corrosion resistant alloy liner pipe i

  12. My Career: Group Fitness Instructor

    Science.gov (United States)

    Green, Kathleen

    2013-01-01

    This article presents an interview with Tammy Kenney, who teaches a yoga-Pilates class in several different gyms. In this interview, Kenney talks about her career as a group fitness instructor and gives her best advice for someone who wants to teach group fitness.

  13. Female Fitness in the Blogosphere

    Directory of Open Access Journals (Sweden)

    Jesper Andreasson

    2013-07-01

    Full Text Available This article analyzes self-portrayals and gender constructions among female personal trainers within an Internet-mediated framework of fitness culture. The empirical material comes from a close examination of three strategically selected blogs. The result shows that some of the blogs clearly build upon what Connell calls emphasized femininity, as a means of legitimizing and constructing appropriate female fitness. In addition, there are also tendencies of sexualization in text and imagery present. As such, these self-representations are framed within a cultural history of body fitness dominated by stereotypical ways of perceiving masculinity and femininity. However, this does not capture the entire presentation of the self among the analyzed fitness bloggers. The blogs also point in the direction of ongoing negotiations and subversions of traditional gender norms. Among other things, they show how irony and humor are used as a means of questioning normative gender constructions while empowering female fitness and bodyliness.

  14. The benefits of coffee on skeletal muscle.

    Science.gov (United States)

    Dirks-Naylor, Amie J

    2015-12-15

    Coffee is consumed worldwide with greater than a billion cups of coffee ingested every day. Epidemiological studies have revealed an association of coffee consumption with reduced incidence of a variety of chronic diseases as well as all-cause mortality. Current research has primarily focused on the effects of coffee or its components on various organ systems such as the cardiovascular system, with relatively little attention on skeletal muscle. Summary of current literature suggests that coffee has beneficial effects on skeletal muscle. Coffee has been shown to induce autophagy, improve insulin sensitivity, stimulate glucose uptake, slow the progression of sarcopenia, and promote the regeneration of injured muscle. Much more research is needed to reveal the full scope of benefits that coffee consumption may exert on skeletal muscle structure and function.

  15. Intraurethral Injection of Autologous Minced Skeletal Muscle

    DEFF Research Database (Denmark)

    Gräs, Søren; Klarskov, Niels; Lose, Gunnar

    2014-01-01

    PURPOSE: Intraurethral injection of in vitro expanded autologous skeletal muscle derived cells is a new regenerative therapy for stress urinary incontinence. We examined the efficacy and safety of a simpler alternative strategy using freshly harvested, minced autologous skeletal muscle tissue with...... its inherent content of regenerative cells. MATERIALS AND METHODS: A total of 20 and 15 women with uncomplicated and complicated stress urinary incontinence, respectively, received intraurethral injections of minced autologous skeletal muscle tissue and were followed for 1 year. Efficacy was assessed...... events were noted. CONCLUSIONS: Intraurethral injection of minced autologous muscle tissue is a simple surgical procedure that appears safe and moderately effective in women with uncomplicated stress urinary incontinence. It compares well to a more complicated regenerative strategy using in vitro...

  16. The Pleiotropic Effect of Physical Exercise on Mitochondrial Dynamics in Aging Skeletal Muscle

    Directory of Open Access Journals (Sweden)

    Elena Barbieri

    2015-01-01

    Full Text Available Decline in human muscle mass and strength (sarcopenia is one of the principal hallmarks of the aging process. Regular physical exercise and training programs are certain powerful stimuli to attenuate the physiological skeletal muscle alterations occurring during aging and contribute to promote health and well-being. Although the series of events that led to these muscle adaptations are poorly understood, the mechanisms that regulate these processes involve the “quality” of skeletal muscle mitochondria. Aerobic/endurance exercise helps to maintain and improve cardiovascular fitness and respiratory function, whereas strength/resistance-exercise programs increase muscle strength, power development, and function. Due to the different effect of both exercises in improving mitochondrial content and quality, in terms of biogenesis, dynamics, turnover, and genotype, combined physical activity programs should be individually prescribed to maximize the antiaging effects of exercise.

  17. Associations between Active Commuting to School and Health-Related Physical Fitness in Spanish School-Aged Children: A Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Emilio Villa-González

    2015-08-01

    Full Text Available Active commuting (walking or cycling to school has been positively associated with improved fitness among adolescents. However, current evidence lacks information on whether this association persists in children. The aim of this study was to examine the association of active commuting to school with different fitness parameters in Spanish school-aged children. A total of 494 children (229 girls from five primary schools in Granada and Jaén (Spain, aged between eight and 11 years, participated in this cross-sectional study. Participants completed the Assessing Levels of Physical Activity (ALPHA fitness test battery and answered a self-reported questionnaire regarding the weekly travel mode to school. Active commuting to school was significantly associated with higher levels of speed-agility in boys (p = 0.048 and muscle strength of the lower body muscular fitness in girls (p = 0.016. However, there were no significant associations between active commuting to school and cardiorespiratory fitness and upper body muscular fitness. Our findings suggest that active commuting to school was associated with higher levels of both speed-agility and lower body muscular fitness in boys and girls, respectively. Future studies should confirm whether increasing active commuting to school increases speed-agility and muscle strength of the lower body.

  18. Pannexin 1 channels in skeletal muscles

    OpenAIRE

    Cea, Luis A.; Riquelme, Manuel A.; Vargas, Anibal A.; Urrutia, Carolina; Sáez, Juan C.

    2014-01-01

    Normal myotubes and adult innervated skeletal myofibers express the glycoprotein pannexin1 (Panx1). Six of them form a “gap junction hemichannel-like” structure that connects the cytoplasm with the extracellular space; here they will be called Panx1 channels. These are poorly selective channels permeable to ions, small metabolic substrate, and signaling molecules. So far little is known about the role of Panx1 channels in muscles but skeletal muscles of Panx1−/− mice do not show an evident ph...

  19. Vasodilatory mechanisms in contracting skeletal muscle

    DEFF Research Database (Denmark)

    Clifford, Philip S.; Hellsten, Ylva

    2004-01-01

    Skeletal muscle blood flow is closely coupled to metabolic demand, and its regulation is believed to be mainly the result of the interplay of neural vasoconstrictor activity and locally derived vasoactive substances. Muscle blood flow is increased within the first second after a single contraction...... and stabilizes within 30 s during dynamic exercise under normal conditions. Vasodilator substances may be released from contracting skeletal muscle, vascular endothelium, or red blood cells. The importance of specific vasodilators is likely to vary over the time course of flow, from the initial rapid rise...

  20. HIF-1-driven skeletal muscle adaptations to chronic hypoxia: molecular insights into muscle physiology.

    Science.gov (United States)

    Favier, F B; Britto, F A; Freyssenet, D G; Bigard, X A; Benoit, H

    2015-12-01

    Skeletal muscle is a metabolically active tissue and the major body protein reservoir. Drop in ambient oxygen pressure likely results in a decrease in muscle cells oxygenation, reactive oxygen species (ROS) overproduction and stabilization of the oxygen-sensitive hypoxia-inducible factor (HIF)-1α. However, skeletal muscle seems to be quite resistant to hypoxia compared to other organs, probably because it is accustomed to hypoxic episodes during physical exercise. Few studies have observed HIF-1α accumulation in skeletal muscle during ambient hypoxia probably because of its transient stabilization. Nevertheless, skeletal muscle presents adaptations to hypoxia that fit with HIF-1 activation, although the exact contribution of HIF-2, I kappa B kinase and activating transcription factors, all potentially activated by hypoxia, needs to be determined. Metabolic alterations result in the inhibition of fatty acid oxidation, while activation of anaerobic glycolysis is less evident. Hypoxia causes mitochondrial remodeling and enhanced mitophagy that ultimately lead to a decrease in ROS production, and this acclimatization in turn contributes to HIF-1α destabilization. Likewise, hypoxia has structural consequences with muscle fiber atrophy due to mTOR-dependent inhibition of protein synthesis and transient activation of proteolysis. The decrease in muscle fiber area improves oxygen diffusion into muscle cells, while inhibition of protein synthesis, an ATP-consuming process, and reduction in muscle mass decreases energy demand. Amino acids released from muscle cells may also have protective and metabolic effects. Collectively, these results demonstrate that skeletal muscle copes with the energetic challenge imposed by O2 rarefaction via metabolic optimization. PMID:26298291

  1. [Comparative analysis of gas exchange and cardiorespiratory systems reactions to increasing normobaric hypoxia and physical load of swimmers and skiers].

    Science.gov (United States)

    Krivoshchekin, S G; Divert, V E; Mel'nikov, V N; Vodianitskiĭ, S N; Girenko, L A

    2013-01-01

    Qualification comparable groups of young men engaged in cyclic kinds of sports were tested with stepwise accruing loads on bicycle ergometer and 25-minute exponential increasing normobaric hypoxia to final concentration of 10% oxygen. Group of skiers, having the greatest values of the maximal oxygen consumption at muscular work, show the relaxed cardiorespiratory reactions and more falling of blood oxygen in the hypoxia. The swimmers, having restrictions of ventilatory function in the course of trainings, form preadaptation to hypoxia with changes of external respiration and gas exchange functions that allows at hypoxia to better oxygen sate the blood in lungs. The joint assessment of aerobic capacity at physical work and physiological reactions to hypoxia shows the direct relation between individual maximal oxygen consumption and the descent rate of blood oxygen saturation at accruing hypoxia that can be useful at an assessment of a sportsman functional state and its correction at training processes. PMID:23668078

  2. Functional state of the cardiorespiratory system of women with postmastectomy syndrome with different types of attitude to the disease

    Directory of Open Access Journals (Sweden)

    Yuriy Briskin

    2015-08-01

    Full Text Available Purpose: to determine the peculiarities of the functional state of cardiorespiratory system in women with postmastectomy syndrome with different types of attitude to the disease. Material and Methods: analysis of the literature and empirical data; rheography, spirography, the definition of the type of attitude to the disease of personality questionnaires of Institute of Behtereva; methods of mathematical statistics. 115 women with postmastectomy syndrome on clinical stage of rehabilitation were involved in this study. Results: in women with intra- and interpsychic types of attitude to the disease decreased reserve capacity of the cardiovascular and respiratory systems respectively. Conclusions: It was proved that women with a rational relationship to the type of disease show significantly better results of the cardiovascular system compared to interpsychic and intrapsychic.

  3. Role of microRNAs in skeletal muscle hypertrophy

    OpenAIRE

    Hitachi, Keisuke; Tsuchida, Kunihiro

    2014-01-01

    Skeletal muscle comprises approximately 40% of body weight, and is important for locomotion, as well as for metabolic homeostasis. Adult skeletal muscle mass is maintained by a fine balance between muscle protein synthesis and degradation. In response to cytokines, nutrients, and mechanical stimuli, skeletal muscle mass is increased (hypertrophy), whereas skeletal muscle mass is decreased (atrophy) in a variety of conditions, including cancer cachexia, starvation, immobilization, aging, and n...

  4. Omega-3 Fatty Acids and Skeletal Muscle Health

    OpenAIRE

    Stewart Jeromson; Gallagher, Iain J.; Stuart D. R. Galloway; D. Lee Hamilton

    2015-01-01

    Skeletal muscle is a plastic tissue capable of adapting and mal-adapting to physical activity and diet. The response of skeletal muscle to adaptive stimuli, such as exercise, can be modified by the prior nutritional status of the muscle. The influence of nutrition on skeletal muscle has the potential to substantially impact physical function and whole body metabolism. Animal and cell based models show that omega-3 fatty acids, in particular those of marine origin, can influence skeletal muscl...

  5. Comparison of Cardiorespiratory and Metabolic Responses in Kettlebell High-Intensity Interval Training Versus Sprint Interval Cycling.

    Science.gov (United States)

    Williams, Brian M; Kraemer, Robert R

    2015-12-01

    The purpose of this study was to determine the effectiveness of a novel exercise protocol we developed for kettlebell high-intensity interval training (KB-HIIT) by comparing the cardiorespiratory and metabolic responses to a standard sprint interval cycling (SIC) exercise protocol. Eight men volunteered for the study and completed 2 preliminary sessions, followed by two 12-minute sessions of KB-HIIT and SIC in a counterbalanced fashion. In the KB-HITT session, 3 circuits of 4 exercises were performed using a Tabata regimen. In the SIC session, three 30-second sprints were performed, with 4 minutes of recovery in between the first 2 sprints and 2.5 minutes of recovery after the last sprint. A within-subjects' design over multiple time points was used to compare oxygen consumption (V[Combining Dot Above]O2), respiratory exchange ratio (RER), tidal volume (TV), breathing frequency (f), minute ventilation (VE), caloric expenditure rate (kcal·min), and heart rate (HR) between the exercise protocols. Additionally, total caloric expenditure was compared. A significant group effect, time effect, and group × time interaction were found for V[Combining Dot Above]O2, RER, and TV, with V[Combining Dot Above]O2 being higher and TV and RER being lower in the KB-HIIT compared with the SIC. Only a significant time effect and group × time interaction were found for f, VE, kcal·min, and HR. Additionally, total caloric expenditure was found to be significantly higher during the KB-HIIT. The results of this study suggest that KB-HIIT may be more attractive and sustainable than SIC and can be effective in stimulating cardiorespiratory and metabolic responses that could improve health and aerobic performance. PMID:26360962

  6. Exercise increases blood flow to locomotor, vestibular, cardiorespiratory and visual regions of the brain in miniature swine

    Science.gov (United States)

    Delp, M. D.; Armstrong, R. B.; Godfrey, D. A.; Laughlin, M. H.; Ross, C. D.; Wilkerson, M. K.

    2001-01-01

    1. The purpose of these experiments was to use radiolabelled microspheres to measure blood flow distribution within the brain, and in particular to areas associated with motor function, maintenance of equilibrium, cardiorespiratory control, vision, hearing and smell, at rest and during exercise in miniature swine. Exercise consisted of steady-state treadmill running at intensities eliciting 70 and 100 % maximal oxygen consumption (V(O(2),max)). 2. Mean arterial pressure was elevated by 17 and 26 % above that at rest during exercise at 70 and 100 % V(O(2),max), respectively. 3. Mean brain blood flow increased 24 and 25 % at 70 and 100 % V(O(2),max), respectively. Blood flow was not locally elevated to cortical regions associated with motor and somatosensory functions during exercise, but was increased to several subcortical areas that are involved in the control of locomotion. 4. Exercise elevated perfusion and diminished vascular resistance in several regions of the brain related to the maintenance of equilibrium (vestibular nuclear area, cerebellar ventral vermis and floccular lobe), cardiorespiratory control (medulla and pons), and vision (dorsal occipital cortex, superior colliculi and lateral geniculate body). Conversely, blood flow to regions related to hearing (cochlear nuclei, inferior colliculi and temporal cortex) and smell (olfactory bulbs and rhinencephalon) were unaltered by exercise and associated with increases in vascular resistance. 5. The data indicate that blood flow increases as a function of exercise intensity to several areas of the brain associated with integrating sensory input and motor output (anterior and dorsal cerebellar vermis) and the maintenance of equilibrium (vestibular nuclei). Additionally, there was an intensity-dependent decrease of vascular resistance in the dorsal cerebellar vermis.

  7. The position of a standard optical computer mouse affects cardiorespiratory responses during the operation of a computer under time constraints

    Directory of Open Access Journals (Sweden)

    Shunji Sako

    2014-08-01

    Full Text Available Objectives: This study investigated the association between task-induced stress and fatigue by examining the cardiovascular responses of subjects using different mouse positions while operating a computer under time constraints. Material and Methods: The study was participated by 16 young, healthy men and examined the use of optical mouse devices affixed to laptop computers. Two mouse positions were investigated: (1 the distal position (DP, in which the subjects place their forearms on the desk accompanied by the abduction and flexion of their shoulder joints, and (2 the proximal position (PP, in which the subjects place only their wrists on the desk without using an armrest. The subjects continued each task for 16 min. We assessed differences in several characteristics according to mouse position, including expired gas values, autonomic nerve activities (based on cardiorespiratory responses, operating efficiencies (based on word counts, and fatigue levels (based on the visual analog scale – VAS. Results: Oxygen consumption (VO2, the ratio of inspiration time to respiration time (Ti/Ttotal, respiratory rate (RR, minute ventilation (VE, and the ratio of expiration to inspiration (Te/Ti were significantly lower when the participants were performing the task in the DP than those obtained in the PP. Tidal volume (VT, carbon dioxide output rates (VCO2/VE, and oxygen extraction fractions (VO2/VE were significantly higher for the DP than they were for the PP. No significant difference in VAS was observed between the positions; however, as the task progressed, autonomic nerve activities were lower and operating efficiencies were significantly higher for the DP than they were for the PP. Conclusions: Our results suggest that the DP has fewer effects on cardiorespiratory functions, causes lower levels of sympathetic nerve activity and mental stress, and produces a higher total workload than the PP. This suggests that the DP is preferable to the PP when

  8. Fitness consultations in routine care of patients with type 2 diabetes in general practice: an 18-month non-randomised intervention study

    DEFF Research Database (Denmark)

    Lohmann, H.; Siersma, V.; Olivarius, Niels de Fine

    2010-01-01

    with an arm curl test and a chair stand test. The results were used in a subsequent motivational interview conducted by one of the GPs. Patients were encouraged to engage in lifestyle exercise and simple home-based self-managed exercise programmes. Data were analysed with mixed models. RESULTS: At end...... of motivational interviewing combined with fitness tests in the type 2 diabetes care programme was followed by a change in cardio-respiratory fitness expressed by VO2max, muscle strength of upper and lower extremities, haemoglobin A1c (HbA1c) and HDL-cholesterol. METHODS: Uncontrolled 18-month intervention study...... with follow-up and effect assessment every 3 months in a primary care unit in Denmark with six general practitioners (GPs). Of 354 eligible patients with type 2 diabetes, 127 (35.9%) were included. Maximum work capacity was tested on a cycle ergometer and converted to VO2max. Muscle strength was measured...

  9. ALFA: Automated Line Fitting Algorithm

    Science.gov (United States)

    Wesson, R.

    2015-12-01

    ALFA fits emission line spectra of arbitrary wavelength coverage and resolution, fully automatically. It uses a catalog of lines which may be present to construct synthetic spectra, the parameters of which are then optimized by means of a genetic algorithm. Uncertainties are estimated using the noise structure of the residuals. An emission line spectrum containing several hundred lines can be fitted in a few seconds using a single processor of a typical contemporary desktop or laptop PC. Data cubes in FITS format can be analysed using multiple processors, and an analysis of tens of thousands of deep spectra obtained with instruments such as MUSE will take a few hours.

  10. Opas CrossFit -harjoitteluun

    OpenAIRE

    Knaapi, Matti

    2014-01-01

    CrossFit on laji, joka pyrkii edistämään terveyttä ja kuntoa. CrossFit saleja löytyy mailmalta yli 10 000 kappaletta. CrossFit -harjoittelussa pyritään parantamaan ihmisen kuntoa mahdollisimman laajalla skaalalla kehittämällä mm. voimaa, kestävyyttä, tarkkuutta, tasapainoa ja eri aineenvaihduntareittejä samanaikaisesti. Terveyden ja kunnon kehittämiseen kuuluu kuntoilun lisäksi myös muita osa-alueita. Ruokavalio ja kehonhuolto ovat tärkeitä osa-alueita hyvän kunnon saavuttamiseksi. Ruokav...

  11. The fitness value of information

    CERN Document Server

    Bergstrom, Carl T

    2007-01-01

    Biologists measure information in different ways. Neurobiologists and researchers in bioinformatics often measure information using information-theoretic measures such as Shannon's entropy or mutual information. Behavioral biologists and evolutionary ecologists more commonly use decision-theoretic measures, such the value of information, which assess the worth of information to a decision maker. Here we show that these two kinds of measures are intimately related in the context of biological evolution. We present a simple model of evolution in an uncertain environment, and calculate the increase in Darwinian fitness that is made possible by information about the environmental state. This fitness increase -- the fitness value of information -- is a composite of both Shannon's mutual information and the decision-theoretic value of information. Furthermore, we show that in certain cases the fitness value of responding to a cue is exactly equal to the mutual information between the cue and the environment. In gen...

  12. Fitness Doping and Body Management

    DEFF Research Database (Denmark)

    Thualagant, Nicole

    specifically in a sport-for-all context. It is questioned whether the anti-doping policy contradicts some of the national sport-for-all organisation, DGI’s values of fostering fellowship, challenge and health. Last but not least, this thesis examines in a third paper the bodywork of the users’ of the club......This PhD thesis examines in a first paper the conceptualization of fitness doping and its current limitations. Based on a review of studies on bodywork and fitness doping it is emphasised that the definition of doping does not provide insights into bodywork of both men and women. Moreover......-based fitness centres. Based on a survey in ten Danish club-based fitness centres and on narratives from semi-structured interviews, it is highlighted that the objectives of bodywork differ according to the users’ age and gender. Two different ways of investing in the body are explored in the paper, namely...

  13. Dance Your Way to Fitness

    Science.gov (United States)

    If traditional dance does not appeal to you, there are other ways to get moving to rhythm and music. Many health clubs and fitness centers offer dance workout classes, such as Zumba. These classes mix moves ...

  14. Kinematic Fitting of Detached Vertices

    Energy Technology Data Exchange (ETDEWEB)

    Mattione, Paul [Rice Univ., Houston, TX (United States)

    2007-05-01

    The eg3 experiment at the Jefferson Lab CLAS detector aims to determine the existence of the $\\Xi_{5}$ pentaquarks and investigate the excited $\\Xi$ states. Specifically, the exotic $\\Xi_{5}^{--}$ pentaquark will be sought by first reconstructing the $\\Xi^{-}$ particle through its weak decays, $\\Xi^{-}\\to\\pi^{-}\\Lambda$ and $\\Lambda\\to\\pi^{-}$. A kinematic fitting routine was developed to reconstruct the detached vertices of these decays, where confidence level cuts on the fits are used to remove background events. Prior to fitting these decays, the exclusive reaction $\\gamma D\\rightarrow pp\\pi^{-}$ was studied in order to correct the track measurements and covariance matrices of the charged particles. The $\\Lambda\\rightarrow p\\pi^{-}$ and $\\Xi^{-}\\to\\pi^{-}\\Lambda$ decays were then investigated to demonstrate that the kinematic fitting routine reconstructs the decaying particles and their detached vertices correctly.

  15. Mechanotransduction pathways in skeletal muscle hypertrophy.

    Science.gov (United States)

    Yamada, André Katayama; Verlengia, Rozangela; Bueno Junior, Carlos Roberto

    2012-02-01

    In the last decade, molecular biology has contributed to define some of the cellular events that trigger skeletal muscle hypertrophy. Recent evidence shows that insulin like growth factor 1/phosphatidyl inositol 3-kinase/protein kinase B (IGF-1/PI3K/Akt) signaling is not the main pathway towards load-induced skeletal muscle hypertrophy. During load-induced skeletal muscle hypertrophy process, activation of mTORC1 does not require classical growth factor signaling. One potential mechanism that would activate mTORC1 is increased synthesis of phosphatidic acid (PA). Despite the huge progress in this field, it is still early to affirm which molecular event induces hypertrophy in response to mechanical overload. Until now, it seems that mTORC1 is the key regulator of load-induced skeletal muscle hypertrophy. On the other hand, how mTORC1 is activated by PA is unclear, and therefore these mechanisms have to be determined in the following years. The understanding of these molecular events may result in promising therapies for the treatment of muscle-wasting diseases. For now, the best approach is a good regime of resistance exercise training. The objective of this point-of-view paper is to highlight mechanotransduction events, with focus on the mechanisms of mTORC1 and PA activation, and the role of IGF-1 on hypertrophy process. PMID:22171534

  16. Mechanotransduction pathways in skeletal muscle hypertrophy.

    Science.gov (United States)

    Yamada, André Katayama; Verlengia, Rozangela; Bueno Junior, Carlos Roberto

    2012-02-01

    In the last decade, molecular biology has contributed to define some of the cellular events that trigger skeletal muscle hypertrophy. Recent evidence shows that insulin like growth factor 1/phosphatidyl inositol 3-kinase/protein kinase B (IGF-1/PI3K/Akt) signaling is not the main pathway towards load-induced skeletal muscle hypertrophy. During load-induced skeletal muscle hypertrophy process, activation of mTORC1 does not require classical growth factor signaling. One potential mechanism that would activate mTORC1 is increased synthesis of phosphatidic acid (PA). Despite the huge progress in this field, it is still early to affirm which molecular event induces hypertrophy in response to mechanical overload. Until now, it seems that mTORC1 is the key regulator of load-induced skeletal muscle hypertrophy. On the other hand, how mTORC1 is activated by PA is unclear, and therefore these mechanisms have to be determined in the following years. The understanding of these molecular events may result in promising therapies for the treatment of muscle-wasting diseases. For now, the best approach is a good regime of resistance exercise training. The objective of this point-of-view paper is to highlight mechanotransduction events, with focus on the mechanisms of mTORC1 and PA activation, and the role of IGF-1 on hypertrophy process.

  17. Interleukin-6 myokine signaling in skeletal muscle

    DEFF Research Database (Denmark)

    Muñoz-Cánoves, Pura; Scheele, Camilla; Pedersen, Bente K;

    2013-01-01

    Interleukin (IL)-6 is a cytokine with pleiotropic functions in different tissues and organs. Skeletal muscle produces and releases significant levels of IL-6 after prolonged exercise and is therefore considered as a myokine. Muscle is also an important target of the cytokine. IL-6 signaling has b...

  18. Tissue engineering skeletal muscle for orthopaedic applications

    Science.gov (United States)

    Payumo, Francis C.; Kim, Hyun D.; Sherling, Michael A.; Smith, Lee P.; Powell, Courtney; Wang, Xiao; Keeping, Hugh S.; Valentini, Robert F.; Vandenburgh, Herman H.

    2002-01-01

    With current technology, tissue-engineered skeletal muscle analogues (bioartificial muscles) generate too little active force to be clinically useful in orthopaedic applications. They have been engineered genetically with numerous transgenes (growth hormone, insulinlike growth factor-1, erythropoietin, vascular endothelial growth factor), and have been shown to deliver these therapeutic proteins either locally or systemically for months in vivo. Bone morphogenetic proteins belonging to the transforming growth factor-beta superfamily are osteoinductive molecules that drive the differentiation pathway of mesenchymal cells toward the chondroblastic or osteoblastic lineage, and stimulate bone formation in vivo. To determine whether skeletal muscle cells endogenously expressing bone morphogenetic proteins might serve as a vehicle for systemic bone morphogenetic protein delivery in vivo, proliferating skeletal myoblasts (C2C12) were transduced with a replication defective retrovirus containing the gene for recombinant human bone morphogenetic protein-6 (C2BMP-6). The C2BMP-6 cells constitutively expressed recombinant human bone morphogenetic protein-6 and synthesized bioactive recombinant human bone morphogenetic protein-6, based on increased alkaline phosphatase activity in coincubated mesenchymal cells. C2BMP-6 cells did not secrete soluble, bioactive recombinant human bone morphogenetic protein-6, but retained the bioactivity in the cell layer. Therefore, genetically-engineered skeletal muscle cells might serve as a platform for long-term delivery of osteoinductive bone morphogenetic proteins locally.

  19. Training induced adaptation in horse skeletal muscle

    NARCIS (Netherlands)

    Dam, K.G. van

    2006-01-01

    It appears that the physiological and biochemical adaptation of skeletal muscle to training in equine species shows a lot of similarities with human and rodent physiological adaptation. On the other hand it is becoming increasingly clear that intra-cellular mechanisms of adaptation (substrate transp

  20. Engineering skeletal muscle tissue in bioreactor systems

    Institute of Scientific and Technical Information of China (English)

    An Yang; Li Dong

    2014-01-01

    Objective To give a concise review of the current state of the art in tissue engineering (TE) related to skeletal muscle and kinds of bioreactor environment.Data sources The review was based on data obtained from the published articles and guidelines.Study selection A total of 106 articles were selected from several hundred original articles or reviews.The content of selected articles is in accordance with our purpose and the authors are authorized scientists in the study of engineered muscle tissue in bioreactor.Results Skeletal muscle TE is a promising interdisciplinary field which aims at the reconstruction of skeletal muscle loss.Although numerous studies have indicated that engineering skeletal muscle tissue may be of great importance in medicine in the near future,this technique still represents a limited degree of success.Since tissue-engineered muscle constructs require an adequate connection to the vascular system for efficient transport of oxygen,carbon dioxide,nutrients and waste products.Moreover,functional and clinically applicable muscle constructs depend on adequate neuromuscular junctions with neural calls.Third,in order to engineer muscle tissue successfully,it may be beneficial to mimic the in vivo environment of muscle through association with adequate stimuli from bioreactors.Conclusion Vascular system and bioreactors are necessary for development and maintenance of engineered muscle in order to provide circulation within the construct.