WorldWideScience

Sample records for cardioplegic agents morphological

  1. Cardioplegia using low volumic cardioplegic agents: morphological study in isolated rabbit hearts Cardioplegia utilizando baixo volume de agentes cardioplégicos: estudo morfológico em coração isolado de coelhos

    OpenAIRE

    Ana Paula Marques de Lima-Oliveira; Maria Tercília Vilela Azeredo-Oliveira; Sebastião Roberto Taboga; Moacir Fernandes de Godoy; Domingo Marcolino Braile

    2003-01-01

    INTRODUCTION: Pharmacological cardioplegic solution aims to eliminate the consequences of ischemic damage, which results from the misbalance between the offer and consumption of energy during the arrest of the heart beats during cardiac surgery with cardiopulmonary bypass. OBJECTIVES: This research experimentally evaluates the structural and ultrastructural changes in isolated rabbit hearts submitted to arrest protected by a Low Volumetric Cardioplegic Solution (LVCS). MATERIAL AND METHOD: Th...

  2. Cardioplegia using low volumic cardioplegic agents: morphological study in isolated rabbit hearts Cardioplegia utilizando baixo volume de agentes cardioplégicos: estudo morfológico em coração isolado de coelhos

    Directory of Open Access Journals (Sweden)

    Ana Paula Marques Lima-Oliveira

    2003-09-01

    Full Text Available INTRODUCTION: Pharmacological cardioplegic solution aims to eliminate the consequences of ischemic damage, which results from the misbalance between the offer and consumption of energy during the arrest of the heart beats during cardiac surgery with cardiopulmonary bypass. OBJECTIVES: This research experimentally evaluates the structural and ultrastructural changes in isolated rabbit hearts submitted to arrest protected by a Low Volumetric Cardioplegic Solution (LVCS. MATERIAL AND METHOD: The study counted with a control group and two experimental groups. In group I the cardiac arrest was obtained by infusion of the LVCS for 2 hours. In group II the experiment was conducted in the same way until the arrest protected by LVCS for 2 hours, and immediately after reperfusion was performed with the Ringer Locke (RL oxygenated solution for 1 hour. In the control group the hearts were perfused with the RL oxygenated solution for 2 hours. After the experiments, 8 samples of the left ventricle were fixed in 10% formaldehyde and 2.5% glutaraldehyde for histological and ultrastructural analysis. RESULTS: The myocardial cells, the fibroblasts and the endothelial cells which were observed in the experimental groups I and II, presented with marginalization of the heterochromatin, compaction of the nucleolus, change in the morphology of the mitochondria and compaction of the cristae. Also there was an increase of the density of the mitochondrial matrix. This indicates that the nuclear structure as well as the structure of the cytoplasmic organelles were altered when compared to the cells of the control group. CONCLUSION: The structural modifications were due a physiological adaptation of the cell, and not an indication of oncosis or apoptosis, suggesting that the cardioplegic solution used was efficient for the preservation of the cells.INTRODUÇÃO: A solução cardioplégica farmacológica busca eliminar as conseqüências do dano isquêmico, que é o

  3. Lowered threshold for ventricular fibrillation in amiodarone-treated pigs undergoing cardiopulmonary bypass and cardioplegic arrest with St. Thomas' cardioplegic solution

    DEFF Research Database (Denmark)

    Gøtzsche, L S; Pedersen, Erik Morre; Paulsen, P K

    1993-01-01

    The antiarrhythmic agent amiodarone has been suspected of causing reduced cardiac performance after extracorporeal circulation and cardioplegic arrest in patients. This has recently been confirmed in an experimental model where pigs were exposed to cardiopulmonary bypass and cold cardioplegic...... arrest with Bretschneider's solution. Due to the high concentration of the cardio-depressant agent procain in Bretschneider's solution, it could be speculated whether it is the combination of amiodarone and this solution that may be potentially deleterious, rather than amiodarone alone. To investigate...... this, adult pigs (75 +/- 2 kg at surgery) were treated with amiodarone for 30 +/- 2 days (1400 mg/day: n = 8, untreated controls: n = 4, blind experiment), followed by exposure to cardiopulmonary bypass with universal cooling to 28 degrees C and topical cold cardioplegic arrest with St. Thomas...

  4. Development of cardioplegic solution without potassium: experimental study in rat

    Directory of Open Access Journals (Sweden)

    Karla Reichert

    2013-12-01

    Full Text Available INTRODUCTION: Myocardial preservation during open heart surgeries and harvesting for transplant are of great importance. The heart at the end of procedure has to resume its functions as soon as possible. All cardioplegic solutions are based on potassium for induction of cardioplegic arrest. OBJECTIVE: To assess a cardioplegic solution with no potassium addition to the formula with two other commercially available cardioplegic solutions. The comparative assessment was based on cytotoxicity, adenosine triphosphate myocardial preservation, and caspase 3 activity. The tested solution (LIRM uses low doses of sodium channel blocker (lidocaine, potassium channel opener (cromakalin, and actin/myosin cross bridge inhibitor (2,3-butanedione monoxime. METHODS: Wistar rats underwent thoracotomy under mechanical ventilation and three different solutions were used for "in situ" perfusion for cardioplegic arrest induction: Custodiol (HTK, Braile (G/A, and LIRM solutions. After cardiac arrest, the hearts were excised and kept in cold storage for 4 hours. After this period, the hearts were assessed with optical light microscopy, myocardial ATP content and caspase 3 activity. All three solutions were evaluated for direct cytotoxicity with L929 and WEHI-164 cells. RESULTS: The ATP content was higher in the Custodiol group compared to two other solutions (P<0.05. The caspase activity was lower in the HTK group compared to LIRM and G/A solutions (P<0.01. The LIRM solution showed lower caspase activity compared to Braile solution (P<0.01. All solutions showed no cytotoxicity effect after 24 hours of cells exposure to cardioplegic solutions. CONCLUSION: Cardioplegia solutions without potassium are promised and aminoacid addition might be an interesting strategy. More evaluation is necessary for an optimal cardioplegic solution development.

  5. [Effectiveness of protecting the myocardium against ischemia with a normothermic cardioplegic solution and creatine phosphate].

    Science.gov (United States)

    Popov, Iu V; Saprygin, D B; Egorova, I F; Kashtélian, L S; Bakuleva, N P

    1985-01-01

    The protective effects of cardioplegic solutions (CS) containing creatine phosphate (CP) were studied in a rat heart model of cardiopulmonary bypass and ischemic cardiac arrest. Isolated rat hearts were subjected to a 3-minute coronary infusion with CS containing CP in normothermic (37 degrees C) and hypothermic (4-6 degrees C) regimes. In the normothermia group, the postischemic functional recovery was 70-75% of the preischemic control value, while the cellular ATP and CP content was reduced but insignificantly. By contrast, in the hypothermia group, the postischemic functional recovery was markedly depressed, with the tissue high-energy phosphate content being appreciably lowered. The data obtained confirm high efficacy of CP-containing cardioplegic solutions administered under normothermia conditions. PMID:3967061

  6. Metabolic Monitoring of Postischemic Myocardium during Intermittent Warm-Blood Cardioplegic Administration

    OpenAIRE

    Borowski, A; Kurt, M.; Calvo, S.; Paprotny, G; Godehardt, E; Fraessdorf, J.; Ghodsizad, A.

    2010-01-01

    In 12 patients undergoing elective myocardial revascularization with intermittent administration of warm-blood cardioplegic solution for myocardial protection, we analyzed metabolic changes by assay of global ischemia indicators (pH, lactate, glucose, and potassium), which we measured in the coronary sinus and arterial blood during the ischemic and post-ischemic periods. A typical cumulative ischemic pattern with progressively decreasing pH values and progressively increasing lactate values c...

  7. The Compatibility Effect Of Coupling Agent On Rheological-Morphological Relationship Of Banana Fibre Reinforced Polypropylene

    International Nuclear Information System (INIS)

    The rheological properties of banana fibre reinforced polypropylene (PP/BF) composites at different composition were analysed using Shimadzu capillary rheometer. The effect of coupling agent concentration on the rheological properties was studied and followed by drawing a relationship of rheological-morphological properties of PP/BF composites. It was found that all composite system exhibits pseudoplasticity and incorporation of treated fibres consequents enhanced viscosity due to improved interfacial adhesion at fibre-matrix interface. However, it was observed that PP/BF composite with 2 wt% silane concentration does not yield further enhancement in the rheological properties when compared to that of 1 wt%. Composites with 1 wt% silane concentration were found to yield most promising compatibility effect with well-oriented and uniformly dispersed fibre morphology.

  8. Concentration Effect of Reducing Agents on Green Synthesis of Gold Nanoparticles: Size, Morphology, and Growth Mechanism.

    Science.gov (United States)

    Kim, Hyun-Seok; Seo, Yu Seon; Kim, Kyeounghak; Han, Jeong Woo; Park, Youmie; Cho, Seonho

    2016-12-01

    Under various concentration conditions of reducing agents during the green synthesis of gold nanoparticles (AuNPs), we obtain the various geometry (morphology and size) of AuNPs that play a crucial role in their catalytic properties. Through both theoretical and experimental approaches, we studied the relationship between the concentration of reducing agent (caffeic acid) and the geometry of AuNPs. As the concentration of caffeic acid increases, the sizes of AuNPs were decreased due to the adsorption and stabilizing effect of oxidized caffeic acids (OXCAs). Thus, it turns out that optimal concentration exists for the desired geometry of AuNPs. Furthermore, we investigated the growth mechanism for the green synthesis of AuNPs. As the caffeic acid is added and adsorbed on the surface of AuNPs, the aggregation mechanism and surface free energy are changed and consequently resulted in the AuNPs of various geometry. PMID:27119158

  9. Morphological, Serological and Molecular Analyses of Anthracnose-Causing Agent on Banana Fruit

    Directory of Open Access Journals (Sweden)

    Nataša Duduk

    2009-01-01

    Full Text Available Two species of the genus Colletotrichum, C. musae and C. gloeosporoides, occur as infecting species of banana. The study focused on examining the etiology of anthracnose on banana fruits sold on the domestic market. An isolate was obtained from a deseased banana fruit on PDA medium, forming a white colony with intensive and uniformed growth. It was not possible to identify the isolated fungus based on its morphological characteristics. Positive serological reaction in an ELISA test with monoclonal antibodies for C. acutatum indicated an antigen site for the used monoclonal antibodies. Positive reaction when C. gloeosporioides-specific primers were applied indicated a similarity in the ITS sequence ofthe fungus and the examined isolate from banana fruit. Although there are no available data in literature that C. gloeosporioides-specific CgInt primer can be used for amplification of the phylogenetically related C. musae, our results do not exclude that the isolate could be C. musae. The host plant, symptoms observed and colony characteristics of the fungus isolated from the banana fruit mostly correspond to C. musae. Based on morphological, antigenand gentic characteristics, the isolate from banana was determined as Colletotrichum sp., while species identification of the anthracnose-causing agent on banana requires additional analysis.

  10. Morphological and molecular characterization of the causal agent of downy mildew on Quinoa (Chenopodium quinoa).

    Science.gov (United States)

    Choi, Young-Joon; Danielsen, Solveig; Lübeck, Mette; Hong, Seung-Beom; Delhey, Rolf; Shin, Hyeon-Dong

    2010-05-01

    Downy mildew is an economically important and widespread disease in quinoa (Chenopodium quinoa) growing areas. Although in many studies Peronospora farinosa is most commonly regarded as the causal agent of the disease, identification and classification of the pathogen remain still uncertain due to its taxonomic confusion. Thirty-six Peronospora isolates from quinoa with different geographic origins including Argentina, Bolivia, Denmark, Ecuador, and Peru were morphologically and molecularly compared with Peronospora species from other Chenopodium species. The morphology of three herbarium specimens was similar to that of P. variabilis, which originated from C. album, characterized by flexuous to curved ultimate branchlets and pedicellated conidia. Phylogenetic analysis based on ITS rDNA sequences also placed the quinoa pathogen within the same clade as P. variabilis. Within the ITS rDNA sequences of the quinoa pathogens, two base substitutions were found, which separated the majority of the Danish isolates from isolates from South America, but no sequence difference was found among the isolates from different cultivars of quinoa. The present results indicate that the pathogen responsible for the quinoa downy mildew is identical to Peronospora variabilis and that it should not be lumped with P. farinosa as claimed previously by most studies. PMID:20101524

  11. The influence of flower morphology and nectar quality on the longevity of a parasitoid biological control agent

    NARCIS (Netherlands)

    Vattala, H.D.; Wratten, S.D.; Phillips, C.B.; Wäckers, F.L.

    2006-01-01

    Conservation biological control aims to enhance the efficacy of arthropod biological control agents, such as parasitoids, partly by providing them with access to floral nectar. However, the suitability of a flower species for providing nectar to a parasitoid is dependent on the morphologies of the p

  12. Effects of antistatic agent on the mechanical, morphological and antistatic properties of polypropylene/organo-montmorillonite nanocomposites

    Directory of Open Access Journals (Sweden)

    2009-02-01

    Full Text Available Polypropylene (PP and PP/organo-montmorillonite (OMMT compounds containing antistatic agent (3, 6 and 9 wt% were prepared using co-rotating twin screw extruder followed by injection molding. PP/OMMT composites were prepared by mixing of PP, OMMT and maleated PP (PPgMAH. The mechanical properties of PP blends and PP/OMMT nanocomposites were studied by tensile and impact tests. The effect of antistatic agent (AA on the surface resistivity of PP and PP/OMMT nanocomposites were studied. The morphological properties of PP blends and PP/OMMT nanocomposites were characterized by using field emission scanning electron microscopy (FESEM. The intercalation of OMMT silicates layer in PP nanocomposites was characterized using X-ray diffraction (XRD. The impact strength of PP blends and PP/OMMT nanocomposites did not vary significantly by the addition of antistatic agent. The tensile modulus and tensile strength of PP/OMMT nanocomposites were slightly decreased with the increasing loading of antistatic agents. From FESEM analysis, the dispersion of antistatic agent in the PP matrix can be revealed. In addition, the surface resistivity of PP/OMMT compound was affected by the loading of antistatic agent. XRD results indicated the formation of intercalated nanocomposites for PP/OMMT/AA.

  13. The Influence of Surface-Active Agent on the Micro-Morphology and Crystallinity of Spherical Hexagonal Boron Nitride.

    Science.gov (United States)

    Zhang, Ning; Liu, Huan; Kan, Hongmin; Wang, Xiaoyang; Long, Haibo; Zhou, Yonghui

    2015-08-01

    This search used the low-cost boric acid and borax as a source of boron, urea as a nitrogen source, surface-active agent Dodecyl benzenesulfonic acid (SDBS) as a dispersant, and thus prepared different micro-morphology and crystallinity hexagonal boron nitride powders under a flowing ammonia atmosphere at a nitriding temperature of 900 °C. The effect of the surface-active agent (SDBS) content on the crystallinity and micro-morphology of hexagonal boron nitride powders was studied, and the corresponding relationship between micro-morphology and crystallinity was explored. The results showed that under a certain synthetic process (900 °C for 3 h), the surfactant content had affected the crystallinity and micro-morphology of h-BN powders. Without the added surfactant, the graphitization index (GI) was 3.61, and micro-morphology of h-BN powders. was spherical, the distribution of ball diameters was uneven, and there was also significant particle agglomeration, with some particles even exhibiting adhesion, sintering necks, and high sphericity and diameter. When the added SDBS percentages were 2%, 4% and 6%, the graphitization index (GI) decreased to 2.98, 2.58 and 2.41 respectively: the corresponding crystallinity improved significantly. When the surfactant SDBS content was higher (10%), the diameter distribution of the h-BN powders was even, but there was evidence of agglomeration of particles and particle adhesion. The crystallinity decreased when the GI value was increased to 4. When the surfactant SDBS content was 6%, the dispersion of h-BN powders was at its optimum, and the particle size distribution was at its most uniform. Meanwhile the GI value was at its lowest, and the crystallinity at its highest. PMID:26369229

  14. FIBRE FLOC MORPHOLOGY AND DEWATERABILITY OF A PULP SUSPENSION: ROLE OF FLOCCULATION KINETICS AND CHARACTERISTICS OF FLOCCULATION AGENTS

    Directory of Open Access Journals (Sweden)

    Henrikki Liimatainen

    2009-05-01

    Full Text Available The aim of this investigation was to find out how properties of a flocculation agent and flocculation kinetics affect the morphology of fibre flocs and how dewatering of a fibre suspension may be attributed to floc morphology. Fibre flocculation, analysed in terms of floc size, mass fractal dimension, floc strength, and the kinetic constant of flocculation, was measured with a digital image analysis system using cationic polyacrylamides as flocculants and NaCl as a coagulant. The results suggest that the kinetics of fibre flocculation is not a key factor determining floc properties but follows from the high bonding ability of the flocculation agent, which also lies behind the high floc density and size, i.e., the factors that lead to fast flocculation and improved floc properties are partly the same. In addition to interfibre bonding strength, the structure of the bonding layer of polymeric flocculants was found to be a significant factor describing floc morphology. Dewaterability of the fibre suspension was improved by increased floc density, which promotes fast water flow through the large voids around the dense flocs, while large, irregular flocs induced loose floc packing, which further improved dewatering by creating larger voids. Increased floc strength seemed to reduce the sealing of fluid passageways, particularly on the surface of the wire, where fibre squeezing could blind the filter fabric.

  15. Epitheliocystis agents in sea bream Sparus aurata: morphological evidence for two distinct chlamydia-like developmental cycles.

    Science.gov (United States)

    Crespo, S; Zarza, C; Padrós, F; Marín de Mateo, M

    1999-06-23

    The morphology of membrane-bound intracellular inclusions, or 'cysts', of epitheliocystis from sea bream Sparus aurata is described. Inclusions under the light microscope appear either granular or amorphous. Granular inclusions do not elicit a proliferative host reaction and contain the 3 distinctive developmental stages of chlamydial organisms: the highly pleomorphic reproductive form or reticulate body, the condensing form or intermediate body and the infective non-dividing rather uniform elementary body. Amorphous inclusions may elicit a proliferative host reaction and contain prokaryotic organisms which differ morphologically from those reported within granular cysts. More or less elongated electron-lucent organisms divide by fission to give rise to electron-dense non-dividing small cells with a dense nucleoid. Vacuolated and non-vacuolated small cells are reported. The morphology and developmental cycle of sea bream epitheliocystis agents would support their chlamydial nature; however, the immunohistochemical study conducted on gill samples which carried both inclusions failed to demonstrate the expression of lipopolysaccharide (LPS) chlamydial antigen. The different stages of the 2 distinct developmental cycles described in the present study are compared with electron microscope observations of epitheliocystis organisms reported from different host species. The hypothesis that epitheliocystis infection in the sea bream might be caused by a unique highly pleomorphic chlamydia-like agent, the life history of which includes 2 entirely different developmental cycles, is discussed. PMID:10439904

  16. A Study on the Morphology of a Dispersed Particle Gel Used as a Profile Control Agent for Improved Oil Recovery

    Directory of Open Access Journals (Sweden)

    Qing You

    2014-01-01

    Full Text Available To achieve in-depth profile control of injection water and improve oil recovery, a new profile control agent, termed as dispersed particle gel (DPG, has been developed and reported. In this paper, the morphology of DPG and the factors that influence its morphology are systematically investigated using atomic force microscopy (AFM. The AFM studies show that DPG is composed of small pseudospherical particles and that their sizes can be controlled by adjusting the shearing rate, the initial polymer mass concentration, and the salinity. Dynamic light scattering (DLS is used to study the effects of the initial polymer mass concentration, the shearing rate, the salinity, and the high-temperature aging on the particle size of DPG. The aggregation ability of DPG is explained using the DLVO theory and space stability theory. This work provides a scientific basis and technical support for the formula design of DPG and its application in the oil and gas field.

  17. Morphology-Controlled Synthesis Of SrTiO3 Nanocube By Capping Agent-Assisted Solvothermal Method

    Directory of Open Access Journals (Sweden)

    Yulia Eka Putri

    2016-05-01

    Full Text Available The synthesis of SrTiO3 nanocubes have been carried out by solvothermal process using cetyl trimethyl ammonium bromide (CTAB as capping agent to control the particles morphology. The condition of the synthesis was obtained at 160 ºC for 24 hours with molar ratio of SrTiO3 and capping agent was 1 : 1. The X-ray diffraction (XRD pattern shows that SrTiO3 adopts a perovskite structure with a higher intensity of 110 at 2q:32.33º and the crystallite size calculated from FWHM was found to be 41 nm. Fourier transform infrared (FTIR spectrum shows a shift in particular absorption band attributed the interaction between SrTiO3 particles surface and the head group of CTAB molecules. Transmission electron microscopy (TEM image shows the cubic-like particles of SrTiO3, this indicatesthat CTAB successfully functions as capping agent on the synthesis of SrTiO3.

  18. Evaluation of a new calcium containing cardioplegic solution in the isolated rabbit heart in comparison to a calcium-free, low sodium solution.

    Science.gov (United States)

    Mori, F; Suzuki, K; Noda, H; Kato, T; Tsuboi, H; Miyamoto, M; Esato, K; Imamura, A; Kawahara, S; Uchiyama, J

    1991-03-01

    Isolated perfused rabbit hearts were studied to compare the effects of 3 hour ischemic arrest following either calcium-free or calcium-containing cardioplegia, on the recovery of isovolumic function of the left ventricle, coronary flow, release of creatine phosphokinase and myocardial water content. The hearts perfused with the calcium-containing solution (Ca 0.5 mmol/L) showed better recovery of the developed pressure in the left ventricle, and its first derivative and compliance. Coronary flow at a constant perfusion pressure was better restored during reperfusion in the hearts with calcium-containing solution. The release of less CPK and a lower water content were also observed in the hearts reperfused with calcium-containing solution. We concluded that calcium-containing cardioplegic solution with a high concentration of magnesium (10 mmol/L) was superior to calcium-free solution for myocardial protection. PMID:2051666

  19. Effect of two bleaching agents on enamel morphology: a SEM study

    Directory of Open Access Journals (Sweden)

    Ghavam M.

    2005-05-01

    Full Text Available Statement of Problem: Bleaching materials are able to change the surface morphology as well as mineral and organic content of tooth structure. Considering that bleaching is done for aesthetic purpose, awareness of the possible effect of these materials on hard tissue is important, because it may affect the restorative treatments. Purpose: The aim of this study was comparing the effect of two bleaching materials, Kimia and Ultradent both containing 35% H2O2, on tooth enamel by SEM. Materials and Methods: Five intact central incisors were cut into three sections vertically and each part was randomly divided into three groups. Group 1 (control, without any bleaching. Group 2, bleached with Kimia 35% H2O2. Group 3, bleached with Ultradent 35% H2O2. Each tooth served as its own control. Then the samples were observed by SEM with 250 and 500 magnifications. Results: In the control group some scratches and small white grains were observed which seems to be the result of mastication trauma and pumice powder. In the other groups, morphologic changes like increased surface roughness, deepening of cracks, rod exposure and presence of new cracks were observed. The two experimental materials did not differ in these regards. Conclusion: It seems that both studied materials have limited destructive effects on tooth enamel which seems to be of no clinical importance.

  20. Histidine and other amino acids in blood and urine after administration of Bretschneider solution (HTK) for cardioplegic arrest in patients: effects on N-metabolism.

    Science.gov (United States)

    Teloh, Johanna K; Dohle, Daniel-Sebastian; Petersen, Miriam; Verhaegh, Rabea; Waack, Indra N; Roehrborn, Friederike; Jakob, Heinz; de Groot, Herbert

    2016-06-01

    Bretschneider (histidine-tryptophan-ketoglutarate, HTK) solution employed for induction of cardioplegic arrest possesses a high histidine concentration (198 mM). Due to the large volume administered, massive amounts of histidine are incorporated. The aim of the study was to evaluate alterations in amino acid and nitrogen metabolism originating from histidine degradation. Between 07/2014 and 10/2014, a total of 29 consecutive patients scheduled for elective isolated coronary artery bypass grafting with cardiopulmonary bypass (CPB) were enrolled in this prospective observational study. The patients received 1.6 L cardioplegic Bretschneider solution on average. Blood gas and urine samples obtained were analyzed for amino acid as well as urea and ammonium concentrations. After CPB initiation, plasma histidine concentration greatly increased to 21,000 µM to reach 8000 µM at the end. Within the operative period, plasma concentrations of aspartate, glutamate, asparagine, alanine, and glutamine increased variable in magnitude. During the same time, urinary analysis revealed histidine excretion of 19,500 µmol in total and marked elevations in glutamate and glutamine excretion. The absolute amounts of urea and ammonium excreted additionally were 3 mmol and 8 mmol, respectively. Already during CPB, distinct amounts of the histidine administered are metabolized, mainly to other amino acids, but only small amounts to urea and ammonia. Thus, the impact of the histidine incorporated on acid-base status in the intraoperative phase is minor. On the other hand, intraoperative provision of several amino acids arising from histidine metabolism might mitigate postaggression syndrome. PMID:26922473

  1. Morphological transformation of an established Syrian hamster dermal cell with the anti-tussive agent noscapine.

    Science.gov (United States)

    Porter, R; Parry, E M; Parry, J M

    1992-05-01

    Following exposure to the alkaloid noscapine hydrochloride over a concentration range of 10-120 micrograms/ml immortal cultures of Syrian hamster dermal fibroblasts were shown to undergo morphological transformation. The resultant transformed foci produced cultures which were anchorage independent as confirmed by soft agar tests. Karyotype analysis of a noscapine transformed colony demonstrated an increase in chromosome number compared to the immortal culture and the non-random duplication of a translocated chromosome 9 previously identified in the immortal culture. These data indicate that noscapine, which has previously been shown to be a spindle inhibitor and inducer of polyploidy in cultured cells, is capable of inducing in vitro cell transformation. Such data indicate a carcinogenic potential for this widely used cough suppressant. PMID:1602976

  2. Influence of Selective Biochemical and Morphological Agents on Natural History of Aneurysm of Abdominal Aorta Development.

    Science.gov (United States)

    Wołoszko, Tomasz; Skórski, Maciej; Kwasiborski, Przemysław; Kmin, Ewelina; Gałązka, Zbigniew; Pogorzelski, Ryszard

    2016-01-01

    BACKGROUND The development of abdominal aortic aneurysm (AAA) is probably influenced by many factors. The role of some of these factors, such as intraluminal thrombus (ILT) or cystatin C serum levels, remains controversial. Proving their influence could have therapeutic implications for some patients with AAA. Associations between the rate of increase in diameter of an aneurysm and ILT, as well as other factors, including biochemical factors (C-Reactive Protein - CRP, cystatin C), age, sex, and comorbidities, could predict disease progression in individual patients. MATERIAL AND METHODS Seventy patients with small AAA were included into the study. The patients were followed using ultrasound and CT imaging. We evaluated aneurysm dimensions and aneurysm wall thickness, as well as ILT and its dimensions, aneurysm wall morphology, CRP, and cystatin C. RESULTS We observed significant growth of AAA and thinning of aneurysmal wall. Aneurysms over 4 cm grew significantly faster in the second year of observation. ILT grew together with AAA size. Age, sex, smoking, dyslipidemias, or controlled arterial hypertension had no influence on aneurysm progression rate. Changes in serum of CRP concentration did not reach statistical significance, but cystatin C levels did. CONCLUSIONS Presence and size of ILT, wall thickness, and cystatin C levels may be considered in prediction of AAA progression. ILT might exert a protective influence on the risk of aneurysm rupture. However, larger aneurysms containing larger thrombi grow faster and their walls undergo more rapid degradation, which in turn increases the risk of rupture. This matter requires further studies. PMID:26859744

  3. Hypoxia-mimetic agents inhibit proliferation and alter the morphology of human umbilical cord-derived mesenchymal stem cells

    Directory of Open Access Journals (Sweden)

    Zeng Hui-Lan

    2011-08-01

    Full Text Available Abstract Background The therapeutic efficacy of human mesenchymal stem cells (hMSCs for the treatment of hypoxic-ischemic diseases is closely related to level of hypoxia in the damaged tissues. To elucidate the potential therapeutic applications and limitations of hMSCs derived from human umbilical cords, the effects of hypoxia on the morphology and proliferation of hMSCs were analyzed. Results After treatment with DFO and CoCl2, hMSCs were elongated, and adjacent cells were no longer in close contact. In addition, vacuole-like structures were observed within the cytoplasm; the rough endoplasmic reticulum expanded, and expanded ridges were observed in mitochondria. In addition, DFO and CoCl2 treatments for 48 h significantly inhibited hMSCs proliferation in a concentration-dependent manner (P Conclusions The hypoxia-mimetic agents, DFO and CoCl2, alter umbilical cord-derived hMSCs morphology and inhibit their proliferation through influencing the cell cycle.

  4. Influence of corn flour as pore forming agent on porous ceramic material based mullite: Morphology and mechanical properties

    Directory of Open Access Journals (Sweden)

    Ayala-Landeros J.G.

    2016-01-01

    Full Text Available Porous material was processed by the mixing, molding and pressing the ceramic material, afterward burnout and sintering; through the forming porous, using corn flour at different concentration (10, 15 and 20 wt.% as a pore forming agent; in order to determinate the influence of porous on the mechanical, morphological and structural properties. The effect of the volume fraction of corn flour in the mullite matrix, at various sintering temperature from 1100, 1200, 1300 and 1500°C were tested by Diffraction X ray, showing changes in crystalline phases of mullite (3Al2O3-2SiO2, as result of sintered temperatures. Presence of talcum powder in formula, also cause the formation of the cordierite and cristobalite crystalline phases, giving stability and adhesion to the structure of ceramic material. When sintering at temperatures between 1300 to 1500°C, and it was used the concentration of corn flour 15-20 wt.% as forming agent porous, it was found the better mechanical properties. The scanning electron microscopy analysis shows the presence of open porosity and anisotropy.

  5. Peroxide bleaching agent effects on enamel surface microhardness, roughness and morphology Efeitos de agentes clareadores à base de peróxidos na microdureza, rugosidade e morfologia superficial do esmalte

    OpenAIRE

    Cristiane Franco Pinto; Rogério de Oliveira; Vanessa Cavalli; Marcelo Giannini

    2004-01-01

    The aim of this study was to evaluate the surface roughness, microhardness and morphology of human enamel exposed to six bleaching agents (at baseline and post-treatment). Human dental enamel samples were obtained from human third molars and randomly divided into seven groups (n = 11): control, Whiteness Perfect - 10% carbamide peroxide (10% CP), Colgate Platinum - 10% CP, Day White 2Z - 7.5% hydrogen peroxide (7.5% HP), Whiteness Super - 37% CP, Opalescence Quick - 35% CP and Whiteness HP - ...

  6. Morphological analysis of microcellular PP produced in a core-back injection process using chemical blowing agents and gas counter pressure

    OpenAIRE

    Reglero Ruiz, José Antonio; Vincent, Michel; Agassant, Jean-François; Claverie, Aurore; Huck, Sébastien

    2015-01-01

    A complete experimental analysis of the microcellular injection process using Chemical Blowing Agents (CBA) with Gas Counter Pressure (GCP) and core-back expansion is presented. Three different types of polypropylene, neat and charged, were mixed with two different CBAs and injected into a plate mold with varying process parameters. First, an exhaustive cartographical mapping of the plate morphology is analyzed. In a second step, the relation between injection parameters and the resulting mor...

  7. Peroxide bleaching agent effects on enamel surface microhardness, roughness and morphology Efeitos de agentes clareadores à base de peróxidos na microdureza, rugosidade e morfologia superficial do esmalte

    Directory of Open Access Journals (Sweden)

    Cristiane Franco Pinto

    2004-12-01

    Full Text Available The aim of this study was to evaluate the surface roughness, microhardness and morphology of human enamel exposed to six bleaching agents (at baseline and post-treatment. Human dental enamel samples were obtained from human third molars and randomly divided into seven groups (n = 11: control, Whiteness Perfect - 10% carbamide peroxide (10% CP, Colgate Platinum - 10% CP, Day White 2Z - 7.5% hydrogen peroxide (7.5% HP, Whiteness Super - 37% CP, Opalescence Quick - 35% CP and Whiteness HP - 35% HP. Bleaching agents were applied according to manufacturers' instructions. The control group remained not treated and stored in artificial saliva. Microhardness testing was performed with a Knoop indentor and surface roughness was analyzed with a profilometer. Morphologic observations were carried out with scanning electron microscopy (SEM. Results were statistically analyzed by two-way analysis of variance and Tukey's test (5%, and revealed a significant decrease in microhardness values and a significant increase in surface roughness post-bleaching. Changes in enamel morphology after bleaching were observed under SEM. It was concluded that bleaching agents can alter the microhardness, roughness and morphology of dental enamel surface.O objetivo deste estudo foi avaliar a rugosidade, microdureza e morfologia superficial do esmalte dental humano tratado com seis agentes clareadores (antes e depois do tratamento. Amostras de esmalte dental humano foram obtidas de terceiros molares e aleatoriamente distribuídas em sete grupos (n = 11: controle, Whiteness Perfect - peróxido de carbamida a 10% (PC 10%, Colgate Platinum - PC 10%, Day White 2Z - peróxido de hidrogênio a 7,5% (PH 7,5%, Whiteness Super - PC 37%, Opalescence Quick - PC 35% e Whiteness HP - PH 35%. Os agentes clareadores foram aplicados de acordo com as instruções dos fabricantes. O grupo controle permaneceu sem tratamento e armazenado em saliva artificial. O teste de microdureza foi realizado

  8. Synthesis of calcium carbonate using extract components of croaker gill as morphology and polymorph adjust control agent.

    Science.gov (United States)

    Chen, Hao; Qing, Chengsong; Zheng, Jiaoling; Liu, Yuxi; Wu, Gang

    2016-06-01

    Biomimetic synthesis of calcium carbonate with various polymorphs, sizes and morphologies by using organic substrates has become an interesting topic for the last years. Calcium carbonate has been synthesized by the reaction of Na2CO3 and CaCl2 in the presence of extract components of croaker gill. The products were characterized by powder X-ray diffraction (PXRD) and Fourier transform infrared (FT-IR) spectrum, and particle morphologies were observed by scanning electron microscope (SEM). The results show that at lower concentration yellow croaker gill extract has no effect on calcium carbonate crystal polymorph. Calcite was obtained only. But the morphologies of calcite particle change with the increase of the concentration. The corners of the particle change from angular to curved. However, with the further increase of the concentration of yellow croaker gill extract, the calcium carbonate obtained is a mixture of calcite and vaterite. The vaterite component in the mixture rises with increasing concentration of extract solution, indicating that the proteins from the yellow croaker gill during growth play a crucial role in stabilizing and directing the crystal growth. PMID:27040242

  9. Morphology-controlled growth of magnetic iron oxide components on gold nanoparticles as bi-functional agents

    OpenAIRE

    Li, L.; Leung, CW; Ruotolo, A.; Jiang, C; Pong, PWT

    2015-01-01

    Summary form only given. Hybrid nanostructure can inherit the physiochemical properties of its individual components to realize its multi-functionality. The coupling of plasmonic effect of gold nanoparticles with magnetic properties of iron oxide nanoparticles has shown great promise as bi-functional agents allowing simultaneous magnetic resonance imaging (MRI)/computed tomography (CT) imaging and magnetic/photonic thermal therapy. However, since gold and iron oxide are two dissimilar materia...

  10. Effect of poly-α, γ, L-glutamic acid as a capping agent on morphology and oxidative stress-dependent toxicity of silver nanoparticles

    Directory of Open Access Journals (Sweden)

    Stevanović M

    2011-11-01

    Full Text Available Magdalena Stevanović1, Branimir Kovačević2, Jana Petković3, Metka Filipič3, Dragan Uskoković11Institute of Technical Sciences of Serbian Academy of Sciences and Arts, 2Institute of General and Physical Chemistry, Belgrade, Serbia; 3Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, SloveniaAbstract: Highly stable dispersions of nanosized silver particles were synthesized using a straightforward, cost-effective, and ecofriendly method. Nontoxic glucose was utilized as a reducing agent and poly- α, γ, L-glutamic acid (PGA, a naturally occurring anionic polymer, was used as a capping agent to protect the silver nanoparticles from agglomeration and render them biocompatible. Use of ammonia during synthesis was avoided. Our study clearly demonstrates how the concentration of the capping agent plays a major role in determining the dimensions, morphology, and stability, as well as toxicity of a silver colloidal solution. Hence, proper optimization is necessary to develop silver colloids of narrow size distribution. The samples were characterized by Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, field-emission scanning electron microscopy, transmission electron microscopy, and zeta potential measurement. MTT assay results indicated good biocompatibility of the PGA-capped silver nanoparticles. Formation of intracellular reactive oxygen species was measured spectrophotometrically using 2,7-dichlorofluorescein diacetate as a fluorescent probe, and it was shown that the PGA-capped silver nanoparticles did not induce intracellular formation of reactive oxygen species.Keywords: silver nanoparticles, poly-α, γ, L-glutamic, green synthesis, morphology, cytotoxicity

  11. Effects of different cyclodextrins on the morphology, loading and release properties of poly (DL-lactide-co-glycolide)-microparticles containing the hypnotic agent etizolam.

    Science.gov (United States)

    Lopedota, A; Cutrignelli, A; Trapani, A; Boghetich, G; Denora, N; Laquintana, V; Trapani, G; Liso, G

    2007-05-01

    The aim of this study was to gain insight into the feasibility of using microparticles (MPs) constituted by the biodegradable poly (DL-lactide-co-glycolide) (PLGA) and a number of cyclodextrins (CDs) as an orally sustained delivery system of the hypnotic agent etizolam (ETZ). A further aim of the work was to investigate the effects of different CDs on the morphology, loading, and release properties of the MPs prepared. For these purposes, ETZ alone, and ETZ/CD-PLGA loaded MPs were prepared by the W/O/W emulsion-solvent evaporation method. It was found that the release of ETZ in vitro was more prolonged over three days with a kinetic constant proportional to t(1/2). It was also demonstrated that the CDs in these MPs are able to modulate several properties such as morphology, drug loading, and release properties. In fact, marked differences in shape, surface, and encapsulation efficiencies were noted depending on the presence, hydrophilicity, and charge of the CD employed. The obtained results induce us to consider the present ETZ-containing formulations as new valuable tools for the treatment of different insomnia categories. PMID:17454433

  12. Great influence of a small amount of capping agents on the morphology of SnS particles using xanthate as precursor

    Energy Technology Data Exchange (ETDEWEB)

    Han Qiaofeng, E-mail: qiaofenghan@yahoo.com [Key Laboratory for Soft Chemistry and Functional Materials of Ministry Education, Nanjing University of Science and Technology, Nanjing 210094 (China); Wang Meijuan; Zhu Junwu; Wu Xiaodong; Lu Lude [Key Laboratory for Soft Chemistry and Functional Materials of Ministry Education, Nanjing University of Science and Technology, Nanjing 210094 (China); Wang Xin, E-mail: wangx@mail.njust.edu.cn [Key Laboratory for Soft Chemistry and Functional Materials of Ministry Education, Nanjing University of Science and Technology, Nanjing 210094 (China)

    2011-02-03

    Research highlights: Various morphologies of SnS particles were obtained by varying the reaction conditions. Especially, slightly excess of ligands resulted in obvious change of morphology for SnS. The experimental results were reproducible. - Abstract: Several hierarchical tin sulfide (SnS) architectures have been prepared based on the reaction of tin dichloride (SnCl{sub 2}.2H{sub 2}O) with potassium O-ethyldithiocarbonate (ethylxanthate, C{sub 2}H{sub 5}OCS{sub 2}K) via a solvothermal route in N,N-dimethylformamide (DMF) solution at 180 deg. C for 24 h. By varying experimental parameters such as reaction temperature, reaction time and the ratios of reactants, various morphologies of three-dimensional (3D) superstructures assembled by SnS nanosheets, nanoribbons and nanorods were obtained. The as-prepared products were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). For a typical molar ratio of C{sub 2}H{sub 5}OCS{sub 2}K/SnCl{sub 2} = 2, the addition of a slight excess of C{sub 2}H{sub 5}OCS{sub 2}K (molar ratio of C{sub 2}H{sub 5}OCS{sub 2}K/SnCl{sub 2} = 2.4) resulted in one-dimensional growth of lamellar SnS particles and their assembly into flowerlike superstructures. Similarly, for the molar ratio of C{sub 2}H{sub 5}OCS{sub 2}K/SnCl{sub 2} = 2, if a small amount of capping agent (1 mL potassium oleate in 40 mL DMF solution) was employed, SnS microspheres aggregated by nanorods were formed. Possible mechanisms for the formation of 3D SnS microstructures were proposed. Optical properties of the products were also studied.

  13. Great influence of a small amount of capping agents on the morphology of SnS particles using xanthate as precursor

    International Nuclear Information System (INIS)

    Research highlights: Various morphologies of SnS particles were obtained by varying the reaction conditions. Especially, slightly excess of ligands resulted in obvious change of morphology for SnS. The experimental results were reproducible. - Abstract: Several hierarchical tin sulfide (SnS) architectures have been prepared based on the reaction of tin dichloride (SnCl2.2H2O) with potassium O-ethyldithiocarbonate (ethylxanthate, C2H5OCS2K) via a solvothermal route in N,N-dimethylformamide (DMF) solution at 180 deg. C for 24 h. By varying experimental parameters such as reaction temperature, reaction time and the ratios of reactants, various morphologies of three-dimensional (3D) superstructures assembled by SnS nanosheets, nanoribbons and nanorods were obtained. The as-prepared products were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). For a typical molar ratio of C2H5OCS2K/SnCl2 = 2, the addition of a slight excess of C2H5OCS2K (molar ratio of C2H5OCS2K/SnCl2 = 2.4) resulted in one-dimensional growth of lamellar SnS particles and their assembly into flowerlike superstructures. Similarly, for the molar ratio of C2H5OCS2K/SnCl2 = 2, if a small amount of capping agent (1 mL potassium oleate in 40 mL DMF solution) was employed, SnS microspheres aggregated by nanorods were formed. Possible mechanisms for the formation of 3D SnS microstructures were proposed. Optical properties of the products were also studied.

  14. Use of a commercially available nucleating agent to control the morphological development of solution-processed small molecule bulk heterojunction organic solar cells

    KAUST Repository

    Sharenko, Alexander

    2014-08-12

    © the Partner Organisations 2014. The nucleating agent DMDBS is used to modulate the crystallization of solution-processed small molecule donor molecules in bulk heterojunction organic photovoltaic (BHJ OPV) devices. This control over donor molecule crystallization leads to a reduction in optimized thermal annealing times as well as smaller donor molecule crystallites, and therefore more efficient devices, when using an excessive amount of solvent additive. We therefore demonstrate the use of nucleating agents as a powerful and versatile processing strategy for solution-processed, small molecule BHJ OPVs. This journal is

  15. Resolving cryptic species with morphology and DNA; thrips as a potential biocontrol agent of Brazilian peppertree, with a new species and overview of Pseudophilothrips (Thysanoptera)

    Science.gov (United States)

    Molecular and morphological evidence is presented to support the description of a second species of Pseudophilothrips in Brazil in association with Schinus terebinthifolius, an invasive weedy tree in North America. Pseudophilothrips is here recognized as a weakly defined genus comprising 13 describe...

  16. Morphological and Pathogenic Characteristics of the Fungus Cladobotryum dendroides, the Causal Agent of Cobweb Disease of the Cultivated Mushroom Agaricus bisporus in Serbia

    OpenAIRE

    Ivana Potočnik; Emil Rekanović; Svetlana Milijašević; Biljana Todorović; Miloš Stepanović

    2008-01-01

    Twenty isolates were isolated from diseased fruiting bodies of Agaricus bisporus collected from Serbian mushroom farms during 2003-2007. The isolates formed white, cottony, aerial colonies on agar media. With age, conidia and colonies turned yellow and redish. Pathogenicity of these isolates was confirmed by inoculation of harvested basidiomes of A. bisporus and by casing inoculation. Symptoms similar to natural infection were recorded. Based on pathogenicity tests and morphological character...

  17. Morphological and Pathogenic Characteristics of the Fungus Cladobotryum dendroides, the Causal Agent of Cobweb Disease of the Cultivated Mushroom Agaricus bisporus in Serbia

    Directory of Open Access Journals (Sweden)

    Ivana Potočnik

    2008-01-01

    Full Text Available Twenty isolates were isolated from diseased fruiting bodies of Agaricus bisporus collected from Serbian mushroom farms during 2003-2007. The isolates formed white, cottony, aerial colonies on agar media. With age, conidia and colonies turned yellow and redish.Pathogenicity of these isolates was confirmed by inoculation of harvested basidiomes of A. bisporus and by casing inoculation. Symptoms similar to natural infection were recorded. Based on pathogenicity tests and morphological characteristics, the isolates were identified as Cladobotryum dendroides (Bulliard : Fries W. Gams & Hoozemans.

  18. Morphological and Pathogenic Characteristics of the Causal Agents of Dry and Wet Bubble Deseases of White Button Mushroom (Agaricus bisporus (Lange Imbach in Serbia

    Directory of Open Access Journals (Sweden)

    Ivana Potočnik

    2006-01-01

    Full Text Available Diseased fruit bodies of Agaricus bisporus, bearing symptoms similar to those caused by Verticillium fungicola and Mycogone perniciosa, were observed during the screening of eight mushroom farms in Serbia in 2002 and 2003. Nine isolates, forming either appressed white or pale brown colonies on PDA medium, were recovered. The isolates were identified on the basis of their morphological, physiological and pathogenic characteristics, and by comparing them to V. fungicola var. fungicola and M. perniciosa isolates originating from United Kingdom, and V. fungicola var. aleophilum from the USA. Pathogenicity of these isolates was confirmed by casing inoculation, on which occasion symptoms of both dry and wet bubble disease were recorded. Five isolates were identified as Verticillium fungicola(Preuss Hassebrauk var. fungicola (W. Gams & Van Zaayen, and four as Mycogone perniciosa(Magnus Delacroix.

  19. Chronic administration of the neurotrophic agent cerebrolysin ameliorates the behavioral and morphological changes induced by neonatal ventral hippocampus lesion in a rat model of schizophrenia.

    Science.gov (United States)

    Vázquez-Roque, Rubén Antonio; Ramos, Brenda; Tecuatl, Carolina; Juárez, Ismael; Adame, Anthony; de la Cruz, Fidel; Zamudio, Sergio; Mena, Raúl; Rockenstein, Edward; Masliah, Eliezer; Flores, Gonzalo

    2012-01-01

    Neonatal ventral hippocampal lesion (nVHL) in rats has been widely used as a neurodevelopmental model to mimic schizophrenia-like behaviors. Recently, we reported that nVHLs result in dendritic retraction and spine loss in prefrontal cortex (PFC) pyramidal neurons and medium spiny neurons of the nucleus accumbens (NAcc). Cerebrolysin (Cbl), a neurotrophic peptide mixture, has been reported to ameliorate the synaptic and dendritic pathology in models of aging and neurodevelopmental disorder such as Rett syndrome. This study sought to determine whether Cbl was capable of reducing behavioral and neuronal alterations in nVHL rats. The behavioral analysis included locomotor activity induced by novel environment and amphetamine, social interaction, and sensoriomotor gating. The morphological evaluation included dendritic analysis by using the Golgi-Cox procedure and stereology to quantify the total cell number in PFC and NAcc. Behavioral data show a reduction in the hyperresponsiveness to novel environment- and amphetamine-induced locomotion, with an increase in the total time spent in social interactions and in prepulse inhibition in Cbl-treated nVHL rats. In addition, neuropathological analysis of the limbic regions also showed amelioration of dendritic retraction and spine loss in Cbl-treated nVHL rats. Cbl treatment also ameliorated dendritic pathology and neuronal loss in the PFC and NAcc in nVHL rats. This study demonstrates that Cbl promotes behavioral improvements and recovery of dendritic neuronal damage in postpubertal nVHL rats and suggests that Cbl may have neurotrophic effects in this neurodevelopmental model of schizophrenia. These findings support the possibility that Cbl has beneficial effects in the management of schizophrenia symptoms. PMID:21932359

  20. Group morphology

    NARCIS (Netherlands)

    Roerdink, Jos B.T.M.

    2000-01-01

    In its original form, mathematical morphology is a theory of binary image transformations which are invariant under the group of Euclidean translations. This paper surveys and extends constructions of morphological operators which are invariant under a more general group TT, such as the motion group

  1. Massive Multi-Agent Systems Control

    Science.gov (United States)

    Campagne, Jean-Charles; Gardon, Alain; Collomb, Etienne; Nishida, Toyoaki

    2004-01-01

    In order to build massive multi-agent systems, considered as complex and dynamic systems, one needs a method to analyze and control the system. We suggest an approach using morphology to represent and control the state of large organizations composed of a great number of light software agents. Morphology is understood as representing the state of the multi-agent system as shapes in an abstract geometrical space, this notion is close to the notion of phase space in physics.

  2. Agent engineering

    CERN Document Server

    Liu, Jiming; Zhong, Ning; Wang, Patrick S P

    2001-01-01

    Agent engineering concerns the development of autonomous computational or physical entities capable of perceiving, reasoning, adapting, learning, cooperating and delegating in a dynamic environment. It is one of the most promising areas of research and development in information technology, computer science and engineering. This book addresses some of the key issues in agent engineering: What is meant by "autonomous agents"? How can we build agents with autonomy? What are the desirable capabilities of agents with respect to surviving (they will not die) and living (they will furthermore enjoy

  3. Mathematical morphology

    CERN Document Server

    Najman, Laurent

    2013-01-01

    Mathematical Morphology allows for the analysis and processing of geometrical structures using techniques based on the fields of set theory, lattice theory, topology, and random functions. It is the basis of morphological image processing, and finds applications in fields including digital image processing (DSP), as well as areas for graphs, surface meshes, solids, and other spatial structures. This book presents an up-to-date treatment of mathematical morphology, based on the three pillars that made it an important field of theoretical work and practical application: a solid theoretical foun

  4. Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine.

    Science.gov (United States)

    Iles, Tinen L; Howard, Brian; Howard, Stephen; Quallich, Stephen; Rolfes, Christopher; Richardson, Eric; Iaizzo, Hanna R; Iaizzo, Paul A

    2016-01-01

    To date, many pharmacological agents used to treat or prevent arrhythmias in open-heart cases create undesired systemic side effects. For example, antiarrhythmic drugs administered intravenously can produce drops in systemic pressure in the already compromised cardiac patient. While performing open-heart procedures, surgeons will often either create a small port or form a pericardial cradle to create suitable fields for operation. This access yields opportunities for target pharmacological delivery (antiarrhythmic or ischemic preconditioning agents) directly to the myocardial tissue without undesired side effects. We have developed a swine model for testing pharmacological agents for target delivery within the pericardial fluid. While fully anesthetized, each animal was instrumented with a Swan-Ganz catheter as well as left and right ventricle pressure catheters, and pacing leads were placed in the right atrial appendage and the right ventricle. A medial sternotomy was then performed and a pericardial access cradle was created; a plunge pacing lead was placed in the left atrial appendage and a bipolar pacing lead was placed in the left ventricle. Utilizing a programmer and a cardiac mapping system, the refractory period of the atrioventricular node (AVN), atria and ventricles was determined. In addition, atrial fibrillation (AF) induction was produced utilizing a Grass stimulator and time in AF was observed. These measurements were performed prior to treatment, as well as 30 min and 60 min after pericardial treatment. Additional time points were added for selected studies. The heart was then cardiopleged and reanimated in a four chamber working mode. Pressure measurements and function were recorded for 1 hr after reanimation. This treatment strategy model allowed us to observe the effects of pharmacological agents that may decrease the incidence of cardiac arrhythmias and/or ischemic damage, during and after open-heart surgery. PMID:27500319

  5. Micromorphological Evaluation of Dentin Treated with Different Desensitizing Agents

    OpenAIRE

    2013-01-01

    Introduction: The purpose of a desensitizing agent is a permanent coating or filling of dentin surface. Morphological analysis in vitro of this treated surface is essential to understand the interaction between desensitizing agent and hypersensitive dentin. The aim was to evaluate the morphology of four dentin surface treated with desensitizing agents.

  6. Antibiotic Agents

    Science.gov (United States)

    ... either as public health or as non-public health antimicrobial agents. What is the difference between bacteriostats, sanitizers, disinfectants ... bacteria, however, there is considerable controversy surrounding their health benefits. The ... producing agents (Table of Antibacterials) have been used for many ...

  7. Galaxy Morphology

    CERN Document Server

    Buta, Ronald J

    2013-01-01

    Galaxy morphology has many structures that are suggestive of various processes or stages of secular evolution. Internal perturbations such as bars can drive secular evolution through gravity torques that move gas into the central regions and build up a flattened, disk-like central bulge, or which may convert an open spiral pseudoring into a more closed ring. Interaction between individual components of a galaxy, such as between a bar and a dark halo, a bar and a central mass concentration, or between a perturbation and the basic state of a stellar disk, can also drive secular transformations. In this series of lectures, I review many aspects of galaxy morphology with a view to delineating some of the possible evolutionary pathways between different galaxy types.

  8. Noun Morphology

    OpenAIRE

    Santazilia, Ekaitz

    2013-01-01

    This is a study of the Basque noun morphology, which sets out the noun paradigm of historical Basque and the structure of its NP, and then goes on to list the explanations proposed so far for every aspect concerning the formation of that paradigm: first the number/definiteness axis, and then the individual cases, classifying these into primary cases (grammatical and local), secondary cases (those built upon the allative and the genitive), and pseudo-flectional morphemes or non-cases.

  9. Agent, autonomous

    OpenAIRE

    Luciani, Annie

    2007-01-01

    The expression autonomous agents, widely used in virtual reality, computer graphics, artificial intelligence and artificial life, corresponds to the simulation of autonomous creatures, virtual (i.e. totally computed by a program), or embodied in a physical envelope, as done in autonomous robots.

  10. Análise ultra-estrutural do miocárdio usando solução cardioplégica cristalóide com e sem procaína em pacientes submetidos à troca valvar aórtica Ultrastructural study of the myocardium using cardioplegic crystalloid solution with and without procaine in patients undergoing aortic valve replacement

    Directory of Open Access Journals (Sweden)

    Luiz Henrique Dussin

    2008-09-01

    Full Text Available OBJETIVO: Avaliar as alterações ultra-estruturais de dois tipos de cardioplegia (com e sem procaína em corações de pacientes submetidos a troca valvar aórtica eletiva. MÉTODOS: Foram estudados 18 pacientes submetidos a circulação extracorpórea para troca valvular aórtica eletiva, no Hospital de Clínicas de Porto Alegre num período de 10 meses. Cada paciente foi distribuído aleatoriamente em dois grupos: grupo A - oito pacientes que receberam solução cardioplégica sem procaína; grupo B - Dez pacientes que receberam solução cardioplégica com procaína. Em ambos os grupos, o saco pericárdico foi irrigado com solução salina hipotérmica. As biópsias miocárdicas foram realizadas em três momentos: I - antes da parada isquêmica, II- no final do período isquêmico e III-15 minutos após a reperfusão. RESULTADOS: A avaliação ultra-estrutural comparando os grupos nos três momentos não demonstrou diferenças significativas, sendo a média dos escores no grupo A, nos momentos I, II, e III, de 0,1 ± 0,2; 0,4 ± 0,3 e 0,4 ± 0,4. No grupo B, a médio dos escores foi 0,2 ± 0,2; 0,4 ± 0,3 e 0,7 ± 0,2, respectivamente, nos momentos I, II, e III. A curva de CK-MB foi similar entre os dois grupos. O retorno espontâneo do ritmo cardíaco, pós-despinçamento, ocorreu em 70% dos pacientes no grupo B e, em 12,5% no grupo A (p=0,024. CONCLUSÃO: As duas soluções testadas protegeram o miocárdio de forma eficaz e não foi possível demonstrar, em nível ultra-estrutural, a superioridade da solução contendo procaína. Constatou-se que o retorno ao ritmo espontâneo do coração após o despinçamento aórtico foi significativamente maior no grupo que utilizou procaína adicionada à solução.OBJECTIVE: The aim of this study was to assess whether the presence of procaine in crystalloid cardioplegic solution increases myocardial protection at the ultra structural level. METHODS: Eighteen patients that underwent aortic valve

  11. Antifungal agents.

    Science.gov (United States)

    Ryder, N S

    1999-12-01

    At this year's ICAAC Meeting, new data on approximately 20 different antifungal agents were presented, while no new agents were disclosed. Drugs in late development include the triazoles, voriconazole (Pfizer Ltd) and Sch-56592 (Schering-Plough Corp), and the echinocandins, caspofungin (Merck & Co Inc) and FK-463 (Fujisawa Pharmaceutical Co Ltd). In contrast to previous years, presentations on these and earlier developmental compounds were relatively modest in scope, with few significant new data. Little new information appeared on the most recent novel class of agents, the sordarins (Glaxo Wellcome plc). Early clinical results were presented for FK-463, showing acceptable tolerability and dose-dependent efficacy in AIDS-associated esophageal candidiasis. A new liposomal formulation of nystatin (Nyotran; Aronex Pharmaceuticals Inc) was shown to be equivalent to conventional amphotericin B in empiric therapy of presumed fungal infection in neutropenic patients, but with reduced toxicity. Intravenous itraconazole (Janssen Pharmaceutica NV) was an effective prophylactic therapy in invasive pulmonary aspergillosis, while oral itraconazole was discussed as a treatment for fungal infection in heart and liver transplant patients. The allylamine compound, terbinafine (Novartis AG), showed good clinical efficacy against fungal mycetoma, a serious tropical infection. A major highlight was the first presentation of inhibitors of fungal efflux pumps as a strategy for overcoming resistance. MC-510027 (milbemycin alpha-9; Microcide Pharmaceuticals Inc) and its derivatives, potentiated the antifungal activity of triazoles and terbinafine in a number of Candida spp. Another pump inhibitor, MC-005172 (Microcide Pharmaceuticals Inc) showed in vivo potentiation of fluconazole in a mouse kidney infection model. Microcide Pharmaceuticals Inc also presented inhibitors of bacterial efflux pumps. PMID:16113946

  12. Trading Agents

    CERN Document Server

    Wellman, Michael

    2011-01-01

    Automated trading in electronic markets is one of the most common and consequential applications of autonomous software agents. Design of effective trading strategies requires thorough understanding of how market mechanisms operate, and appreciation of strategic issues that commonly manifest in trading scenarios. Drawing on research in auction theory and artificial intelligence, this book presents core principles of strategic reasoning that apply to market situations. The author illustrates trading strategy choices through examples of concrete market environments, such as eBay, as well as abst

  13. Morphological and pathological characterisation of Colletotrichum sp. as casual agent of anthracnose in Dioscorea sp. Caracterización morfológica y patogénica de Colletotrichum sp. como agente causal de la antracnosis en ñame Dioscorea sp.

    OpenAIRE

    Beltrán Herrera Javier Darío; Pérez Castro Libia María; Baquero María José

    2003-01-01

    Colletotrichum gloeosporioides and Colletotrichum dematium strains were isolated from yam plants in the Sucre depart-ment. Macro- and microscopic descriptions were made, finding that the predominant colour for the colonies was light purple. Sporulation was higher than 58,000 conidia/ml for most colonies. Growth rate lay within a range of 4 to 5mm/day. C. gloeosporioide isolate conidial morphology revealed a cylindrical spore having one rounded end whilst the other was acute shaped. Conidia le...

  14. Radioprotective Agents

    Directory of Open Access Journals (Sweden)

    Ilker Kelle

    2008-01-01

    Full Text Available Since1949, a great deal of research has been carried out on the radioprotective activity of various chemical substances. Thiol compounds, compounds which contain –SH radical, different classes of pharmacological agents and other compounds such as vitamine C and WR-2721 have been shown to reduce mortality when administered prior to exposure to a lethal dose of radiation. Recently, honey bee venom as well as that of its components melittin and histamine have shown to be valuable in reduction of radiation-induced damage and also provide prophylactic alternative treatment for serious side effects related with radiotherapy. It has been suggested that the radioprotective activity of bee venom components is related with the stimulation of the hematopoetic system.

  15. An agent framework for dynamic agent retraining: Agent academy

    OpenAIRE

    Mitkas, P.; A. Symeonidis; Kechagias, D.; Athanasiadis, I.N.; Laleci, G.; KURT, G.; Kabak, Y.; Acar, A.; Dogac, A.

    2004-01-01

    Agent Academy (AA) aims to develop a multi-agent society that can train new agents for specific or general tasks, while constantly retraining existing agents in a recursive mode. The system is based on collecting information both from the environment and the behaviors of the acting agents and their related successes/failures to generate a body of data, stored in the Agent Use Repository, which is mined by the Data Miner module, in order to generate useful knowledge about the application domai...

  16. Efeito de reticulante na morfologia e propriedades físico-mecânicas de espumas poliméricas obtidas com EVA e EPDM The effect of a crosslinking agent on the morphology and physical and mechanical properties of polymer foams based on EVA and EPDM

    Directory of Open Access Journals (Sweden)

    Joyce B. Azevedo

    2010-01-01

    this study the effect of a crosslinking agent on EVA/EPDM foams was investigated. The physical, mechanical and rheometric properties, as well as the foam morphology, were analyzed as a function of dicumil peroxide, used as a crosslinking agent. The results showed that this additive has a strong influence in the crooking and expansion of the compounds, affecting their properties.

  17. Agent Chameleons: Virtual Agents Real Intelligence

    OpenAIRE

    O'Hare, Gregory; Duffy, Brian; Schoen-Phelan, Bianca; Martin, Alan; Bradley, John

    2003-01-01

    Agent Chameleons provides virtual agents powered by real intelligence, delivering next generation autonomic entities that can seamlessly migrate, mutate and evolve on their journey between and within physical and digital information spaces.

  18. Morphological and pathological characterisation of Colletotrichum sp. as casual agent of anthracnose in Dioscorea sp. Caracterización morfológica y patogénica de Colletotrichum sp. como agente causal de la antracnosis en ñame Dioscorea sp.

    Directory of Open Access Journals (Sweden)

    Beltrán Herrera Javier Darío

    2003-06-01

    Full Text Available Colletotrichum gloeosporioides and Colletotrichum dematium strains were isolated from yam plants in the Sucre depart-ment. Macro- and microscopic descriptions were made, finding that the predominant colour for the colonies was light purple. Sporulation was higher than 58,000 conidia/ml for most colonies. Growth rate lay within a range of 4 to 5mm/day. C. gloeosporioide isolate conidial morphology revealed a cylindrical spore having one rounded end whilst the other was acute shaped. Conidia length and width averaged between 7-8 micras and 3-4 micras, respectively. C. dematium colonies, however, were characterised by being grey and having radial growth. The fálcate and fusiform conidia tapered at the acute apex. They had a length and width of 16-18 micras and 3-4 micras, respectively. C. gloeosporioides colonies showed different macroscopic morphology but similar microscopic characteristics. Vegeta-tive compatibility was evaluated amongst different geographical isolates resulting in 90% compatibility. A patho-genic assay was done for evaluating isolate virulence on tolerant and susceptible cultivars. The isolates showed great variability regarding their virulence. The Colletotrichum isolate collection represents a tool for use in molecular characterisation and evaluating yam germplasm tolerance to this pathogen. Keywords: Colletotrichum, yam, anthracnose, phytopathology.Cepas de Colletotrichum gloeosporioides y Colletotrichum dematium fueron aisladas de plantas de ñame en el departa­mento de Sucre. Se realizó una descripción macro y microscópica encontrándose que el color predominante de la colonia fue lila. La esporulación fue mayor a 58.000 conidias /ml para la mayoría de las colonias. La rata de creci­miento tuvo un rango entre 4 -7 mm / día. Las conidias de los aislados de Colletotrichum gloeosporioides son cilíndri­cas con un extremo redondeado y el otro agudo y un tamaño que varía entre 7-8 micras y 3-4 micras de ancho. As

  19. Advancement of Molecular Morphology

    Institute of Scientific and Technical Information of China (English)

    顾江

    2004-01-01

    @@ Molecular morphology is a new discipline of medical science that studies morphology at the molecular level. This includes the investigation of occurrence and distribution of proteins, peptides, DNA and RNA sequences at the tissue, cellular, and ultrastructural levels.

  20. A Czech Morphological Lexicon

    OpenAIRE

    Skoumalova, Hana

    1997-01-01

    In this paper, a treatment of Czech phonological rules in two-level morphology approach is described. First the possible phonological alternations in Czech are listed and then their treatment in a practical application of a Czech morphological lexicon.

  1. Advancement of Molecular Morphology

    Institute of Scientific and Technical Information of China (English)

    顾江

    2004-01-01

    Molecular morphology is a new discipline of medical science that studies morphology at the molecular level. This includes the investigation of occurrence and distribution of proteins, peptides, DNA and RNA sequences at the tissue, cellular, and uhrastructural levels. Morphology is defined as a field of science investigating the shape,

  2. Long term morphological modelling

    DEFF Research Database (Denmark)

    Kristensen, Sten Esbjørn; Deigaard, Rolf; Taaning, Martin;

    2010-01-01

    A morphological modelling concept for long term nearshore morphology is proposed and examples of its application are presented and discussed. The model concept combines parameterised representations of the cross-shore morphology, with a 2DH area model for waves, currents and sediment transport in...

  3. Therapy Effect: Impact on Bone Marrow Morphology.

    Science.gov (United States)

    Li, K David; Salama, Mohamed E

    2016-03-01

    This article highlights the most common morphologic features identified in the bone marrow after chemotherapy for hematologic malignancies, growth-stimulating agents, and specific targeted therapies. The key is to be aware of these changes while reviewing post-therapeutic bone marrow biopsies and to not mistake reactive patterns for neoplastic processes. In addition, given the development and prevalent use of targeted therapy, such as tyrosine kinase inhibitors and immune modulators, knowledge of drug-specific morphologic changes is required for proper bone marrow interpretation and diagnosis. PMID:26940276

  4. Morphology and photoluminescence study of titania nanoparticles

    OpenAIRE

    Memesa, Mine; Lenz, Sebastian; Emmerling, Sebastian G. J.; Nett, Sebastian; Perlich, Jan; Müller-Buschbaum, Peter; Gutmann, Jochen S

    2011-01-01

    Titania nanoparticles are prepared by sol–gel chemistry with a poly(ethylene oxide) methyl ether methacrylate-block-poly(dimethylsiloxane)-block-poly(ethylene oxide) methyl ether methacrylate triblock copolymer acting as the templating agent. The sol–gel components—hydrochloric acid, titanium tetraisopropoxide, and triblock copolymer—are varied to investigate their effect on the resulting titania morphology. An increased titania precursor or polymer content yields smaller primary titania stru...

  5. Morphology of galaxies

    CERN Document Server

    Wadadekar, Yogesh

    2012-01-01

    The study of the morphology of galaxies is important in order to understand the formation and evolution of galaxies and their sub-components as a function of luminosity, environment, and star-formation and galaxy assembly over cosmic time. Disentangling the many variables that affect galaxy evolution and morphology, requires large galaxy samples and automated ways to measure morphology. The advent of large digital sky surveys, with unprecedented depth and resolution, coupled with sophisticated quantitative methods for morphology measurement are providing new insights in this fast evolving field of astronomical research.

  6. AgentChess : An Agent Chess Approach

    OpenAIRE

    Fransson, Henric

    2003-01-01

    The game of chess has many times been discussed and used for test purpose by science departments of Artificial Intelligence (AI). Although the technique of agent and as well multi-agent systems is quite old, the use of these offspring of AI within chess is limited. This report describes the project performed applying the use of agents to a chess program. To measure the performance of the logic has tests between the developed program main parts been performed. Further tests against a tradition...

  7. Agents in domestic environments

    OpenAIRE

    van Moergestel, Leo; Langerak, Wouter; Meerstra, Glenn; Nieuwenburg, Niels van; Pape, Franc; Telgen, Daniël; Puik, Erik; meyer, john-jules

    2013-01-01

    Athor supplied : "This paper describes an agent-based architecture for domotics. This architecture is based on requirements about expandability and hardware independence. The heart of the system is a multi-agent system. This system is distributed over several platforms to open the possibility to tie the agents directly to the actuators, sensors and devices involved. This way a level of abstraction is created and all intelligence of the system as a whole is related to the agents involved. A pr...

  8. Culturally Aware Agent Communication

    DEFF Research Database (Denmark)

    Rehm, Matthias; Nakano, Yukiko; Koda, Tomoko;

    2012-01-01

    Agent based interaction in the form of Embodied Conversational Agents (ECAs) has matured over the last decade and agents have become more and more sophisticated in terms of their verbal and nonverbal behavior like facial expressions or gestures. Having such “natural” communication channels...

  9. Riot Control Agents

    Science.gov (United States)

    ... a person has been exposed to riot control agents. Long-term health effects of exposure to riot control agents Prolonged ... person is removed from exposure to riot control agents, long-term health effects are unlikely to occur. How you can ...

  10. Reasoning about emotional agents

    NARCIS (Netherlands)

    Meyer, J.-J.

    2008-01-01

    In this paper we discuss the role of emotions in artificial agent design, and the use of logic in reasoning about the emotional or affective states an agent can reside in. We do so by extending the KARO framework for reasoning about rational agents appropriately. In particular we formalize in this f

  11. Agents modeling agents in information economies

    Energy Technology Data Exchange (ETDEWEB)

    Vidal, J.M.; Durfee, E.H. [Univ. of Michigan, Ann Arbor, MI (United States)

    1996-12-31

    Our goal is to design and build agents that act intelligently when placed in an agent-based information economy, where agents buy and sell services (e.g. thesaurus, search, task planning services, etc.). The economy we are working in is the University of Michigan Digital Library (UMDL), a large scale multidisciplinary effort to build an infrastructure for the delivery of library services. In contrast with a typical economy, an information economy deals in goods and services that are often derived from unique sources (authors, analysts, etc.), so that many goods and services are not interchangeable. Also, the cost of replicating and transporting goods is usually negligible, and the quality of goods and services is difficult to measure objectively: even two sources with essentially the same information might appeal to different audiences. Thus, each agent has its own assessment of the quality of goods and services delivered.

  12. Quantifying patterns of agent-environment interaction

    OpenAIRE

    Tarapore, D.; Lungarella, M; Gomez, G.

    2006-01-01

    This article explores the assumption that a deeper (quantitative) understanding of the information-theoretic implications of sensory-motor coordination can help endow robots not only with better sensory morphologies, but also with better exploration strategies. Specifically, we investigate by means of statistical and information-theoretic measures, to what extent sensory-motor coordinated activity can generate and structure information in the sensory channels of a simulated agent interacting w...

  13. Long term morphological modelling

    DEFF Research Database (Denmark)

    Kristensen, Sten Esbjørn; Deigaard, Rolf; Taaning, Martin; Fredsøe, Jørgen; Drønen, Nils; Hjelmager Jensen, Jacob

    2010-01-01

    concept often used in one-line modelling of cross-shore shifting of an otherwise constant shape cross-shore profile is applied for the case of a groyne and a detached breakwater. In the case of alongshore bar/nourishment migration an alternative parameterization is adopted. All examples are presented......A morphological modelling concept for long term nearshore morphology is proposed and examples of its application are presented and discussed. The model concept combines parameterised representations of the cross-shore morphology, with a 2DH area model for waves, currents and sediment transport in...... the surf zone. Two parameterization schemes are tested for two different morphological phenomena: 1) Shoreline changes due to the presence of coastal structures and 2) alongshore migration of a nearshore nourishment and a bar by-passing a harbour. In the case of the shoreline evolution calculations, a...

  14. Perspectives in Physical Morphology

    OpenAIRE

    Abraham, R. G.

    1998-01-01

    In the first section of these lectures I outline the classical framework of the Hubble classification system. Because of space limitations I will focus on points of controversy concerning the physical interpretation of the Hubble sequence, showing how morphological ideas shape our understanding of galaxy evolution. I will then present an overview of the remarkable progress made in recent years in understanding how the local morphological composition has transformed into that seen the distant ...

  15. Extrinsic morphology of graphene

    OpenAIRE

    Li, Teng

    2011-01-01

    Graphene is intrinsically non-flat and corrugates randomly. Since the corrugating physics of atomically-thin graphene is strongly tied to its electronics properties, randomly corrugating morphology of graphene poses significant challenge to its application in nanoelectronic devices for which precise (digital) control is the key. Recent studies revealed that the morphology of substrate-supported graphene is regulated by the graphene-substrate interaction, thus is distinct from the random intri...

  16. Chemical crowd control agents.

    Science.gov (United States)

    Menezes, Ritesh G; Hussain, Syed Ather; Rameez, Mansoor Ali Merchant; Kharoshah, Magdy A; Madadin, Mohammed; Anwar, Naureen; Senthilkumaran, Subramanian

    2016-03-01

    Chemical crowd control agents are also referred to as riot control agents and are mainly used by civil authorities and government agencies to curtail civil disobedience gatherings or processions by large crowds. Common riot control agents used to disperse large numbers of individuals into smaller, less destructive, and more easily controllable numbers include chloroacetophenone, chlorobenzylidenemalononitrile, dibenzoxazepine, diphenylaminearsine, and oleoresin capsicum. In this paper, we discuss the emergency medical care needed by sufferers of acute chemical agent contamination and raise important issues concerning toxicology, safety and health. PMID:26658556

  17. Decontamination Data - Blister Agents

    Data.gov (United States)

    U.S. Environmental Protection Agency — Decontamination efficacy data for blister agents on various building materials using various decontamination solutions This dataset is associated with the following...

  18. Antimicrobial agent microencapsulation for the development of functionalized primary containers

    OpenAIRE

    Bile, Jessica

    2015-01-01

    First, this work focused on the formulation of microparticles loaded with antimicrobial agent using the emulsion/solvent evaporation method. Several morphologies have been obtained with nonsmooth microparticles characterized by scars and defects, roughness and holes. The parameters and the physico-chemical mechanisms involved in these morphological deteriorations have been identified and discussed. It has been shown that the formulation and processing parameters as the polymer mass and molar ...

  19. Agent Development Toolkits

    CERN Document Server

    Singh, Aarti; Sharma, A K

    2011-01-01

    Development of agents as well as their wide usage requires good underlying infrastructure. Literature indicates scarcity of agent development tools in initial years of research which limited the exploitation of this beneficial technology. However, today a wide variety of tools are available, for developing robust infrastructure. This technical note provides a deep overview of such tools and contrasts features provided by them.

  20. Radiographic scintiscanning agent

    International Nuclear Information System (INIS)

    A new technetium-based scintiscanning agent has been prepared comprising a water soluble sup(99m)Tc-methanehydroxydiphosphonate in combination with a reducing agent selected from stannous, ferrous, chromous and titanous salts. As an additional stabilizer salts and esters of gentisic or ascorbic acids have been used. (E.G.)

  1. Asimovian Adaptive Agents

    CERN Document Server

    Gordon, D F

    2011-01-01

    The goal of this research is to develop agents that are adaptive and predictable and timely. At first blush, these three requirements seem contradictory. For example, adaptation risks introducing undesirable side effects, thereby making agents' behavior less predictable. Furthermore, although formal verification can assist in ensuring behavioral predictability, it is known to be time-consuming. Our solution to the challenge of satisfying all three requirements is the following. Agents have finite-state automaton plans, which are adapted online via evolutionary learning (perturbation) operators. To ensure that critical behavioral constraints are always satisfied, agents' plans are first formally verified. They are then reverified after every adaptation. If reverification concludes that constraints are violated, the plans are repaired. The main objective of this paper is to improve the efficiency of reverification after learning, so that agents have a sufficiently rapid response time. We present two solutions: ...

  2. How do agents represent?

    Science.gov (United States)

    Ryan, Alex

    Representation is inherent to the concept of an agent, but its importance in complex systems has not yet been widely recognised. In this paper I introduce Peirce's theory of signs, which facilitates a definition of representation in general. In summary, representation means that for some agent, a model is used to stand in for another entity in a way that shapes the behaviour of the agent with respect to that entity. Representation in general is then related to the theories of representation that have developed within different disciplines. I compare theories of representation from metaphysics, military theory and systems theory. Additional complications arise in explaining the special case of mental representations, which is the focus of cognitive science. I consider the dominant theory of cognition — that the brain is a representational device — as well as the sceptical anti-representational response. Finally, I argue that representation distinguishes agents from non-representational objects: agents are objects capable of representation.

  3. Hyperthermia and chemotherapy agent

    International Nuclear Information System (INIS)

    The use of chemotherapeutic agents for the treatment of cancer dates back to the late 19th century, but the modern era of chemotherapy drugs was ushered in during the 1940's with the development of the polyfunctional alkylating agent. Since then, numerous classes of drugs have evolved and the combined use of antineoplastic agents with other treatment modalities such as radiation or heat, remains a large relatively unexplored area. This approach, combining local hyperthermia with chemotherapy agents affords a measure of targeting and selective toxicity not previously available for drugs. In this paper, the effects of adriamycin, bleomycin and cis-platinum are examined. The adjuvant use of heat may also reverse the resistance of hypoxic cells noted for some chemotherapy agents

  4. MORPHOLOGICAL AND THERMAL PROPERTIES OF MAIZE STARCH

    Directory of Open Access Journals (Sweden)

    Elena Corina Popescu

    2010-01-01

    Full Text Available Maize, rice, wheat and potato are the main sources of starches which differ significantly in composition, morphology,thermal, rheological and retrogradation properties. Starch has unique thermal properties and functionality that havepermitted its wide use in food products and industrial applications.The structure of the starch granule results from the physical arrangement of amylose and amylopectin. Amylose contentof starches from different maize types ranged between 15.3% and 25.1%. Amylopectin is considered responsible for thecrystalline structure of starch granules.The morphological and physicochemical characteristics of maize starch are related to the enzymes involved in itsbiosynthesis.The surface of the starch granule plays a fundamental rôle as the first barrier to processes such as granule hydration,enzyme attack, and chemical reaction with modifying agents. Major parameters describing the solid surface are:specific surface area, total pore volume, mean pore radius (diameter and pore volume distribution in relation to poreradius (diameter.

  5. Morphological Evaluation of Variously Intercalated Pre-baked Clay

    Directory of Open Access Journals (Sweden)

    Ullah Hameed

    2014-06-01

    Full Text Available The use of porous materials is enjoying tremendous popularity and attention of the advance scientific communities due to their excellent adsorptive and catalytic activities. Clays are one of the most important candidates in the porous community which shows the above mentioned activities after modifing with a different intercalating agent. The paper is focused on the infiuence of some inorganic intercalating agents (NaOH on the morphology of the variously intercalated clay samples. The alkali metal was used as the inorganic intercalating agent. The effect of intercalation temperature, intercalation agent concentration and intercalation time on the pre-baked clay morphology were also part of the study. Scanning electron microscopy (SEM study was performed to evaluate the morphological changes of the resultant intercalates. Different morphological properties were improved significantly in the case of the inorganically modified clay samples. Thus, such intercalations are suggested to be effective if the clays under study are to be used for different industrial process at elevated conditions.

  6. Morphology diagram of a diblock copolymer - aluminosilicate nanoparticle system

    NARCIS (Netherlands)

    Garcia, B.C.; Kamperman, M.M.G.; Ulrich, R.; Jain, A.; Gruner, S.M.; Wiesner, U.

    2009-01-01

    We explore the morphology space of nanocomposites prepared from poly(isoprene-block-ethylene oxide) (PI-b-PEO) diblock copolymers as structure directing agents for aluminosilicate nanoparticles prepared from (3-glycidyloxypropyl)trimethoxysilane (GLYMO) and aluminum(III) sec-butoxide. The results of

  7. Morphological Evolution of Galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Martel, H. [Department of Astronomy, University of Texas, Austin, Texas 78712 (United States); Premadi, P.; Matzner, R. [Center for Relativity, University of Texas, Austin, Texas 78712 (United States); Premadi, P.; Matzner, R. [Department of Physics, University of Texas, Austin, Texas 78712 (United States)

    1998-04-01

    We simulate the growth of large-scale structure for three different cosmological models, an Einstein{endash}de Sitter model (density parameter {Omega}{sub 0} = 1), an open model ({Omega}{sub 0} = 0.2), and a flat model with nonzero cosmological constant ({Omega}{sub 0} = 0.2, cosmological constant {lambda}{sub 0} = 0.8), using a cosmological {ital N}-body code (particle-particle/particle-mesh) with 64{sup 3} dark matter particles in a comoving cubic volume of present comoving size 128 Mpc. The calculations start at {ital z} = 24 and end at {ital z} = 0. We use the results of these simulations to generate distributions of galaxies at the present ({ital z} = 0), as follows: Using a Monte Carlo method based on the present distribution of dark matter, we located {approximately}40,000 galaxies in the computational volume. We then ascribe to each galaxy a morphological type based on the local number density of galaxies in order to reproduce the observed morphology-density relation. The resulting galaxy distributions are similar to the observed ones, with most ellipticals concentrated in the densest regions, and most spirals concentrated in low-density regions. By {open_quotes}tying{close_quotes} each galaxy to its nearest dark matter particle, we can trace the trajectory of that galaxy back in time by simply looking at the location of that dark matter particle at earlier time slices provided by the {ital N}-body code. This enables us to reconstruct the distribution of galaxies at high redshift and the trajectory of each galaxy from its formation epoch to the present. We use these galaxy distributions to investigate the problem of morphological evolution. Our goal is to determine whether the morphological type of galaxies is determined primarily by the initial conditions in which these galaxies form or by evolutionary processes (such as mergers or tidal stripping) occurring after the galaxies have formed and eventually altering their morphology, or a combination of both

  8. Users, Bystanders and Agents

    DEFF Research Database (Denmark)

    Krummheuer, Antonia Lina

    2015-01-01

    Human-agent interaction (HAI), especially in the field of embodied conversational agents (ECA), is mainly construed as dyadic communication between a human user and a virtual agent. This is despite the fact that many application scenarios for future ECAs involve the presence of others. This paper...... the construction of the agent’s identity, and (3) how HAI, as a mediated interaction, is framed by an asymmetric participation framework. The paper concludes by suggesting various participation roles, which may inform development of ECAs....

  9. Agent-Based Optimization

    CERN Document Server

    Jędrzejowicz, Piotr; Kacprzyk, Janusz

    2013-01-01

    This volume presents a collection of original research works by leading specialists focusing on novel and promising approaches in which the multi-agent system paradigm is used to support, enhance or replace traditional approaches to solving difficult optimization problems. The editors have invited several well-known specialists to present their solutions, tools, and models falling under the common denominator of the agent-based optimization. The book consists of eight chapters covering examples of application of the multi-agent paradigm and respective customized tools to solve  difficult optimization problems arising in different areas such as machine learning, scheduling, transportation and, more generally, distributed and cooperative problem solving.

  10. Vocabulary— Teaching Through Morphology

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A large vocabulary is crucial to learners of English, but how to teach vocabulary effectively is equally important to a teacher of English. This article tries to emphasize the importance of part of speech in vocabulary teaching by analyzing the characteristics of English words from the aspect of morphology.

  11. Needlelike morphology of aspartame

    NARCIS (Netherlands)

    Cuppen, H.M.; Eerd, A.R.T. van; Meekes, H.L.M.

    2004-01-01

    The needlelike morphology of aspartame form II-A is studied by means of Monte Carlo simulations. Growth simulations for all F faces show merely three faces with a nucleation barrier for growth: two side faces and one top face. Calculations of the energies involved in the growth for a few representat

  12. Morphology of uranium compounds

    International Nuclear Information System (INIS)

    Uranium metal is being used as nuclear fuel for Indian Research Reactors. During production of U metal various intermediate compounds of uranium are being processed. Physical, chemical properties of these compounds are important in overall processing rate and conversion determination. As no systematic data on morphology of these compounds were available, study was conducted to record the morphology of various U-compounds which are important in production of ceramic and metallic U-fuel for reactors. Most important intermediates were found to be ammonium diuranate (ADU) and uranium oxide (UO3/UO2). Morphology of these powders controls their flowability required for further material movement through different equipment, surface area required for chemical reactivity of powder, carryover losses occurred during gas solid counter current reaction and tap density required for effective capacity determination. ADU particle basically consists of primary platelets of 250-500 nm width and of 500-1000 nm length. These primary platelets form primary agglomerates. These agglomerates look like woollen balls or balls or cauliflower and primary agglomerates are also connected with each other to form secondary agglomerates. The basic morphology of ADU is maintained in UO3 even after calcination at high temperature. Pores are generated at the surface of platelet of UO3 due to release of gaseous reaction products during calcination. As temperature increases more pores are generated and sintering also starts. Specific surface area of UO3, produced by the calcination of ammonium di-urinate is generally a function of two competing processes: generation of surface area due to generation of pores because of the evolution of gaseous products (NH3, H2O vapour) and the loss of surfaces due to sintering. As a results surface area increases with calcination temperature due to generation of pores and then reduces. It has also been observed that morphology of the compounds are very much processing

  13. Agent Standards Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation of the work herein proposed is the development of standards for software autonomous agents. These standards are essential to achieve software...

  14. Programming Service Oriented Agents

    OpenAIRE

    Hirsch, Benjamin; Konnerth, Thomas; Burkhardt, Michael; Albayrak, Sahin

    2010-01-01

    This paper introduces a programming language for service-oriented agents. JADL++ combines the ease of use of scripting-languages with a state-of-the-art service oriented approach which allows the seamless integration of web-services. Furthermore, the language includes OWL-based ontologies for semantic descriptions of data and services, thus allowing agents to make intelligent decisions about service calls.

  15. Adrenal imaging agents

    International Nuclear Information System (INIS)

    The goals of this proposal are the development of selenium-containing analogs of the aromatic amino acids as imaging agents for the pancreas and of the adrenal cortex enzyme inhibitors as imaging agents for adrenal pathology. The objects for this year include (a) the synthesis of methylseleno derivatives of phenylalanine and tryptophan, and (b) the preparation and evaluation of radiolabeled iodobenzoyl derivatives of the selenazole and thiazole analogs of metyrapone and SU-9055

  16. Agent amplified communication

    Energy Technology Data Exchange (ETDEWEB)

    Kautz, H.; Selman, B.; Milewski, A. [AT& T Laboratories, Murray Hill, NJ (United States)

    1996-12-31

    We propose an agent-based framework for assisting and simplifying person-to-person communication for information gathering tasks. As an example, we focus on locating experts for any specified topic. In our approach, the informal person-to-person networks that exist within an organization are used to {open_quotes}referral chain{close_quotes} requests for expertise. User-agents help automate this process. The agents generate referrals by analyzing records of e-mail communication patterns. Simulation results show that the higher responsiveness of an agent-based system can be effectively traded for the higher accuracy of a completely manual approach. Furthermore, preliminary experience with a group of users on a prototype system has shown that useful automatic referrals can be found in practice. Our experience with actual users has also shown that privacy concerns are central to the successful deployment of personal agents: an advanced agent-based system will therefore need to reason about issues involving trust and authority.

  17. Application of Isothermal Amplification Techniques for Identification of Madurella mycetomatis, the Prevalent Agent of Human Mycetoma

    NARCIS (Netherlands)

    Ahmed, Sarah A; van de Sande, Wendy W J; Desnos-Ollivier, Marie; Fahal, Ahmed H; Mhmoud, Najwa A; de Hoog, G S

    2015-01-01

    Appropriate diagnosis and treatment of eumycetoma may vary significantly depending on the causative agent. To date, the most common fungus causing mycetoma worldwide is Madurella mycetomatis. This species fails to express any recognizable morphological characteristics, and reliable identification ca

  18. Surfactant mediated morphological tethering of Cu2O nanoparticles

    International Nuclear Information System (INIS)

    This communication describes a very simple and reproducible methodology to study the self-assembly of nanoparticles functionalized with a non-ionic tethering agent attached to the surface of the nanoparticle seeds. The synthesis starts with the [Cu(OH)4]2− species acting as a template, with varying concentration of the tethering agent Triton X-100 (TX100). The morphological alteration is systematically investigated. The effect of surfactant micelles, growth reaction time, and solution temperature has a tremendous impact on the morphology of the nanocrystals that govern the controlled synthesis of different shapes of nanostructures. The initial morphology of the nanocrystals is polyhedron in the absence of a tethering additive. The addition of TX100 suppresses the polymorph phase morphology and enhances the non-uniform spherical morphology of the nanocrystals. The surface modification effect enhances the morphological alteration, which potentially makes it applicable to various industrial uses such as water cleaning, hydrogen production, and third-generation solar cells. (paper)

  19. Morphological mutants of garlic

    Energy Technology Data Exchange (ETDEWEB)

    Choudhary, A.D.; Dnyansagar, V.R. (Nagpur Univ. (India). Dept. of Botany)

    1982-01-01

    Cloves of garlic (Allium sativuum Linn.) were exposed to gamma rays with various doses and different concentrations of ethylmethane sulphonate (EMS), diethyl sulphate (dES) and ethylene imine (EI). In the second and third generations, 16 types of morphological mutants were recorded with varied frequencies. Of all the mutagens used, gamma rays were found to be the most effective in inducing the maximum number of mutations followed EI, EMS and dES in that order.

  20. Morphological mutants of garlic

    International Nuclear Information System (INIS)

    Cloves of garlic (Allium sativuum Linn.) were exposed to gamma rays with various doses and different concentrations of ethylmethane sulphonate (EMS), diethyl sulphate (dES) and ethylene imine (EI). In the second and third generations, 16 types of morphological mutants were recorded with varied frequencies. Of all the mutagens used, gamma rays were found to be the most effective in inducing the maximum number of mutations followed EI, EMS and dES in that order. (author)

  1. Agent Oriented Programming进展%Advances in Agent Oriented Programming

    Institute of Scientific and Technical Information of China (English)

    王一川; 石纯一

    2002-01-01

    Agent-oriented programming (AOP) is a framework to develop agents, and it aims to link the gap betweentheory and practical in agent research. The core of an AOP framework is its language and semantics. In this paper,we propose the necessary properties which agents should have, and then give a summary and analysis about differentAOP languages based on these properties.

  2. Agents unleashed a public domain look at agent technology

    CERN Document Server

    Wayner, Peter

    1995-01-01

    Agents Unleashed: A Public Domain Look at Agent Technology covers details of building a secure agent realm. The book discusses the technology for creating seamlessly integrated networks that allow programs to move from machine to machine without leaving a trail of havoc; as well as the technical details of how an agent will move through the network, prove its identity, and execute its code without endangering the host. The text also describes the organization of the host's work processing an agent; error messages, bad agent expulsion, and errors in XLISP-agents; and the simulators of errors, f

  3. El agente encubierto

    OpenAIRE

    Anaya Marcos, María del Carmen

    2015-01-01

    [ES] El trabajo versa sobre la figura del agente encubierto. Debemos enmarcar tal medida de investigación dentro del ámbito de la criminalidad organizada. Actualmente, estamos asistiendo a una proliferación de la delincuencia organizada. La sociedad ha evolucionado, y con ella la delincuencia. Fruto de tal evolución fue necesario incluir en nuestra Ley de Enjuiciamiento Criminal medidas extraordinarias de investigación, y una de ellas es el agente encubierto. Se trata de una medida muy polémi...

  4. The PLS agent : agent behavior validation by partial least squares

    OpenAIRE

    Lorscheid, Iris; Meyer, Matthias; Pakur, Sandra; Ringle, Christian

    2014-01-01

    Agent-based modeling is widely applied in the social sciences. However, the validation of agent behavior is challenging and identified as one of the shortcomings in the field. Methods are required to establish empirical links and support the implementation of valid agent models. This paper contributes to this, by introducing the PLS agent concept. This approach shows a way to transfer results about causalities and decision criteria from empirical surveys into an agent-based decision model, th...

  5. Trading Agents for Roaming Users

    OpenAIRE

    Boman, Magnus; Bylund, Markus; Espinoza, Fredrik; Danielson, Mats; Lyback, David

    2002-01-01

    Some roaming users need services to manipulate autonomous processes. Trading agents running on agent trade servers are used as a case in point. We present a solution that provides the agent owners with means to upkeeping their desktop environment, and maintaining their agent trade server processes, via a briefcase service.

  6. Software Agent Techniques in Design

    DEFF Research Database (Denmark)

    Hartvig, Susanne C

    1998-01-01

    This paper briefly presents studies of software agent techniques and outline aspects of these which can be applied in design agents in integrated civil engineering design environments.......This paper briefly presents studies of software agent techniques and outline aspects of these which can be applied in design agents in integrated civil engineering design environments....

  7. 13 CFR 107.1620 - Functions of agents, including Central Registration Agent, Selling Agent and Fiscal Agent.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Functions of agents, including Central Registration Agent, Selling Agent and Fiscal Agent. 107.1620 Section 107.1620 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES SBA Financial Assistance...

  8. Programming multi-agent systems

    NARCIS (Netherlands)

    Dastani, Mehdi

    2015-01-01

    With the significant advances in the area of autonomous agents and multi-agent systems in the last decade, promising technologies for the development and engineering of multi-agent systems have emerged. The result is a variety of agent-oriented programming languages, development frameworks, executio

  9. Experimental impact crater morphology

    Science.gov (United States)

    Dufresne, A.; Poelchau, M. H.; Hoerth, T.; Schaefer, F.; Thoma, K.; Deutsch, A.; Kenkmann, T.

    2012-04-01

    The research group MEMIN (Multidisciplinary Experimental and Impact Modelling Research Network) is conducting impact experiments into porous sandstones, examining, among other parameters, the influence of target pore-space saturation with water, and projectile velocity, density and mass, on the cratering process. The high-velocity (2.5-7.8 km/s) impact experiments were carried out at the two-stage light-gas gun facilities of the Fraunhofer Institute EMI (Germany) using steel, iron meteorite (Campo del Cielo IAB), and aluminium projectiles with Seeberg Sandstone as targets. The primary objectives of this study within MEMIN are to provide detailed morphometric data of the experimental craters, and to identify trends and characteristics specific to a given impact parameter. Generally, all craters, regardless of impact conditions, have an inner depression within a highly fragile, white-coloured centre, an outer spallation (i.e. tensile failure) zone, and areas of arrested spallation (i.e. spall fragments that were not completely dislodged from the target) at the crater rim. Within this general morphological framework, distinct trends and differences in crater dimensions and morphological characteristics are identified. With increasing impact velocity, the volume of craters in dry targets increases by a factor of ~4 when doubling velocity. At identical impact conditions (steel projectiles, ~5km/s), craters in dry and wet sandstone targets differ significantly in that "wet" craters are up to 76% larger in volume, have depth-diameter ratios generally below 0.19 (whereas dry craters are almost consistently above this value) at significantly larger diameters, and their spallation zone morphologies show very different characteristics. In dry craters, the spall zone surfaces dip evenly at 10-20° towards the crater centre. In wet craters, on the other hand, they consist of slightly convex slopes of 10-35° adjacent to the inner depression, and of sub-horizontal tensile

  10. SECOND BUYING AGENT

    CERN Multimedia

    SPL - SERVICES ACHATS

    2000-01-01

    Last year the buying agent LOGITRADE started operations on the CERN site, processing purchasing requests for well-defined families of products up to a certain value. It was planned from the outset that a second buying agent would be brought in to handle the remaining product families. So, according to that plan, the company CHARLES KENDALL will be commencing operations at CERN on 8 May 2000 in Building 73, 1st floor, offices 31 and 35 (phone and fax numbers to be announced).Each buying agent will have its own specific list of product families and will handle purchasing requests up to 10'000 CHF.Whenever possible they will provide the requested supplies at a price (including the cost of their own services) which must be equivalent to or lower than the price mentioned on the purchasing request, changing the supplier if necessary. If a lower price cannot be obtained, agents will provide the necessary administrative support free of charge.To ensure that all orders are processed in the best possible conditions, us...

  11. Radioactive diagnostic agent

    International Nuclear Information System (INIS)

    A dispersion of denatured aggregates of serum albumin to which tin is attached is prepared and lyophilized. A mixture of polycarboxylic acid and a disaccharide or monosaccharide is included in the dispersion in sufficient amount to reduce degradation during lyophilization and aging. The dispersion is suitable for radioactive labelling and use as a diagnostic agent

  12. Developing Enculturated Agents

    DEFF Research Database (Denmark)

    Rehm, Matthias

    Embodied Conversational Agents (ECAs) are complex multimodal systems with rich verbal and nonverbal repertoires. There human-like appearance raises severe expectations regarding natural communicative behaviors on the side of the user. But what is regarded as “natural” is to a large degree dependent...

  13. Biomimetic Emotional Learning Agents

    OpenAIRE

    Kenyon, Samuel H.

    2005-01-01

    This extended abstract proposes a type of AI agent comprised of: an autonomous real-time control system, low-level emotional learning (including a simple knowledge base that links homeostatic/innate drives to sensory perception states), and a novel sliding-priority drive motivation mechanism. Learning occurs in both phylogenetic and ontogenetic training.

  14. Agents of Change

    DEFF Research Database (Denmark)

    Hansen, Jens Aage; Lehmann, Martin

    2004-01-01

    at large, it emphasises universities as key change agents and providers in new learning, including tools such as project based and problem oriented learning (PBL) as well as information and communication technology (ICT); as providers of competent and motivated graduates to fill key positions in society...

  15. The need for agents

    DEFF Research Database (Denmark)

    Abolfazlian, Ali Reza Kian

    1996-01-01

    I denne artikel arbejder vi med begrebet Intelligent Software Agents (ISAs), som autonomous, social, reactive, proactive og subservient computer systemer. Baseret på socialt psykologiske argumenter viser jeg endvidere, hvordan både den menneskelige natur og det teknologiske stadium, som mennesket...

  16. Build Autonomic Agents with ABLE

    Institute of Scientific and Technical Information of China (English)

    吴吉义

    2007-01-01

    The IBM Agent Building and Learning Environment(ABLE) provides a lightweight Java~(TM) agent frame- work,a comprehensive JavaBeansTM library of intelligent software components,a set of development and test tools, and an agent platform.After the introduction to ABLE,classes and interfaces in the ABLE agent framework were put forward.At last an autonomic agent that is an ABLE-based architecture for incrementally building autonomic systems was discussed.

  17. Morphology of urethral tissues

    Science.gov (United States)

    Müller, Bert; Schulz, Georg; Herzen, Julia; Mushkolaj, Shpend; Bormann, Therese; Beckmann, Felix; Püschel, Klaus

    2010-09-01

    Micro computed tomography has been developed to a powerful technique for the characterization of hard and soft human and animal tissues. Soft tissues including the urethra, however, are difficult to be analyzed, since the microstructures of interest exhibit X-ray absorption values very similar to the surroundings. Selective staining using highly absorbing species is a widely used approach, but associated with significant tissue modification. Alternatively, one can suitably embed the soft tissue, which requires the exchange of water. Therefore, the more recently developed phase contrast modes providing much better contrast of low X-ray absorbing species are especially accommodating in soft tissue characterization. The present communication deals with the morphological characterization of sheep, pig and human urethras on the micrometer scale taking advantage of micro computed tomography in absorption and phase contrast modes. The performance of grating-based tomography is demonstrated for freshly explanted male and female urethras in saline solution. The micro-morphology of the urethra is important to understand how the muscles close the urethra to reach continence. As the number of incontinent patients is steadily increasing, the function under static and, more important, under stress conditions has to be uncovered for the realization of artificial urinary sphincters, which needs sophisticated, biologically inspired concepts to become nature analogue.

  18. A Czech Morphological Lexicon

    CERN Document Server

    Skoumalova, H

    1997-01-01

    In this paper, a treatment of Czech phonological rules in two-level morphology approach is described. First the possible phonological alternations in Czech are listed and then their treatment in a practical application of a Czech morphological lexicon. From no-reply@xxx.lanl.gov Thu Oct 7 08:24 MET 1999 Received: from newmint.cern.ch (dxmint.cern.ch [137.138.26.76]) by sundh98.cern.ch (8.8.5/8.8.5) with ESMTP id IAA19870 for ; Thu, 7 Oct 1999 08:24:36 +0200 (MET DST) Received: from yyy.lanl.gov (yyy.lanl.gov [204.121.6.60]) by newmint.cern.ch (8.9.3/8.9.3) with ESMTP id IAA28502 for ; Thu, 7 Oct 1999 08:24:36 +0200 (MET DST) Received: from xxx.lanl.gov (xxx.lanl.gov [204.121.6.57]) by yyy.lanl.gov (x.x.x/x.x.x) with ESMTP id AAA17918; Thu, 7 Oct 1999 00:12:01 -0600 (MDT) Received: (from e-prints@localhost) by xxx.lanl.gov (x.x.x/x.x.x) id AAA25245; Thu, 7 Oct 1999 00:12:08 -0600

  19. Morphological disintegration as a mode of morphological evolution of plants

    OpenAIRE

    Natalya P. Savinykh

    2014-01-01

    Morphological disintegration evaluated as a mode of morphological evolution, condition and adaptation of plants to biotopes the conditions of with high humidity. The value of morphological disintegration and autonomization of the parts of organism in these conditions was shown. The life forms of oligoennial plants, as well as of annual aquatic and coastal-aquatic plants were clarified. The spectrum of biomorphes of oligoennial and annual plants of vegetative origin was represented.

  20. Actions and Agents

    OpenAIRE

    Alonso, E.

    2014-01-01

    In this chapter the notion of agency in AI is presented..It has been argued that in order to behave rationally in prevalent software applications artificial entities would have to be autonomous and adaptive. Besides, rather than working with single, isolated systems the new trend in AI would need to focus on inherently social entities in the form of multi-agent systems. The chapter begins by introducing the notion of action in traditional AI systems, deliberative and reactive. Next, the i...

  1. Towards Soft Computing Agents

    Czech Academy of Sciences Publication Activity Database

    Neruda, Roman; Krušina, Pavel; Petrová, Zuzana

    2000-01-01

    Roč. 10, č. 5 (2000), s. 859-868. ISSN 1210-0552. [SOFSEM 2000 Workshop on Soft Computing. Milovy, 27.11.2000-28.11.2000] R&D Projects: GA ČR GA201/00/1489; GA ČR GA201/99/P057 Institutional research plan: AV0Z1030915 Keywords : hybrid systems * intelligent agents Subject RIV: BA - General Mathematics

  2. Sunscreening Agents: A Review

    OpenAIRE

    Latha, M. S.; Martis, Jacintha; Shobha, V; Sham Shinde, Rutuja; Bangera, Sudhakar; Krishnankutty, Binny; Bellary, Shantala; Varughese, Sunoj; Rao, Prabhakar; B R Naveen Kumar

    2013-01-01

    The increasing incidence of skin cancers and photodamaging effects caused by ultraviolet radiation has increased the use of sunscreening agents, which have shown beneficial effects in reducing the symptoms and reoccurrence of these problems. Many sunscreen compounds are in use, but their safety and efficacy are still in question. Efficacy is measured through indices, such as sun protection factor, persistent pigment darkening protection factor, and COLIPA guidelines. The United States Food an...

  3. Perioperative allergy: uncommon agents.

    Science.gov (United States)

    Caimmi, S; Caimmi, D; Cardinale, F; Indinnimeo, L; Crisafulli, G; Peroni, D G; Marseglia, G L

    2011-01-01

    Anesthesia may often be considered as a high-risk procedure and anaphylaxis remains a major cause of concern for anesthetists who routinely administer many potentially allergenic agents. Neuromuscular blocking agents, latex and antibiotics are the substances involved in most of the reported reactions. Besides these three agents, a wide variety of substances may cause an anaphylactic reaction during anesthesia. Basically all the administered drugs or substances may be potential causes of anaphylaxis. Among them, those reported the most in literature include hypnotics, opioids, local anesthetics, colloids, dye, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Iodinated Contrast Media (ICM), antiseptics, aprotinin, ethylene oxyde and formaldehyde, and protamine and heparins. No premedication can effectively prevent an allergic reaction and a systematic preoperative screening is not justified for all patients; nevertheless, an allergy specialist should evaluate those patients with a history of anesthesia-related allergy. Patients must be fully informed of investigation results, and advised to provide a detailed report prior to future anesthesia. PMID:22014927

  4. Advanced scale conditioning agents

    International Nuclear Information System (INIS)

    A technical description of Advanced Scale Conditioning Agents (ASCA) technology was published in the May-June 2003 edition of the Nuclear Plant Journal. That article described the development of programs of advanced scale conditioning agents and specific types to maintain the secondary side of steam generators within a pressurized water reactor free of deposited corrosion products and corrosion-inducing contaminants to ensure their long-term operation. This article describes the first two plant applications of advanced scale conditioning agents implemented at Southern Nuclear Operating Company's Vogtle Units 1 and 2 during their 2002 scheduled outages to minimize tube degradation and maintain full power operation using the most effective techniques while minimizing outage costs. The goal was to remove three to four fuel cycles of deposits from each steam generator so that after future chemical cleaning activities, ASCAs could be used to maintain the cleanliness of the steam generators without the need for additional chemical cleaning efforts. The goal was achieved as well as several other benefits that resulted in cost savings to the plant

  5. SAM : Semantic Agent Model for SWRL rule-based agents

    OpenAIRE

    Subercaze, Julien; Maret, Pierre

    2010-01-01

    International audience SemanticWeb technologies are part of multi-agent engineering, especially regarding knowledge base support. Recent advances in the field of logic for the semantic web enable a new range of applications. Among them, programming agents based on semantic rules is a promising field. In this paper we present a semantic agent model that allows SWRL programming of agents. Our approach, based on the extended finite state machine concept, results in a three layers architecture...

  6. Mechanical and morphological characterization of polypropylene toughened with olefinic elastomer

    OpenAIRE

    Cybele Lotti; Carlos A. Correa; Canevarolo, Sebastião V

    2000-01-01

    The effect of incorporating (C2-C8) ethylene-octene elastomer on the mechanical properties and morphology of polypropylene copolymers has been investigated employing two types of PP copolymer, with and without nucleating agent. The results were compared to the ones presented by a commercial PP heterophase (reactor impact modified PP/EPR). The addition of the elastomer increases the toughness of the blends but reduces their stiffness. PP blends in the low elastomer content region (< 20%) show ...

  7. Morphological effects of MMPs inhibitors on the dentin bonding

    OpenAIRE

    Li, He; Li, Tianbo; Li, Xiuying; Zhang, Zhimin; Li, Penglian; Li, Zhenling

    2015-01-01

    Matrix metalloproteinases (MMPs) have been studied extensively, and MMP inhibitors have been used as dental pretreatment agents prior to dentin bonding because they reduce collagen fiber degradation and improve bonding strength. However, morphologic characteristics of the collagen network after etching and of the post-adhesive dentin hybrid layers (DHL) after MMP inhibitors pretreatment have not been evaluated. Thus, we investigated demineralized dentin pretreated with chlorhexidine (CHX) and...

  8. Morphological and Thermal Properties of Cellulose Nanofibrils Reinforced Epoxy Nanocomposites

    OpenAIRE

    Deniz Aydemir

    2015-01-01

    Epoxy resins have gained attention as important adhesives because they are structurally stable, inert to most chemicals, and highly resistant to oxidation. Different particles can be added to adhesives to improve their properties. In this study, cellulose nanofibrils (CNFs), which have superior mechanical properties, were used as the reinforcing agent. Cellulose nanofi brils were added to epoxy in quantities of 1 %, 2 % and 3 % by weight to prepare nanocomposites. Morphological characterizati...

  9. Peripheral Neuropathy and Agent Orange

    Science.gov (United States)

    ... Enter ZIP code here Peripheral Neuropathy and Agent Orange VA presumes Veterans' early-onset peripheral neuropathy is related to their exposure to Agent Orange or other herbicides during service when the disease ...

  10. Agents Play Mix-game

    CERN Document Server

    Gou, C

    2005-01-01

    In mix-game which is an extension of minority game, there are two groups of agents; group1 plays the majority game, but the group2 plays the minority game. This paper studies the change of the average winnings of agents and volatilities vs. the change of mixture of agents in mix-game model. It finds that the correlations between the average winnings of agents and the mean of local volatilities are different with different combinations of agent memory length when the proportion of agents in group 1 increases. This study result suggests that memory length of agents in group1 be smaller than that of agent in group2 when mix-game model is used to simulate the financial markets.

  11. The Power Trading Agent Competition

    OpenAIRE

    Ketter, W.; Collins, J.; REDDY, P; Flath, C.

    2011-01-01

    This is the specification for the Power Trading Agent Competition for 2011 (Power TAC 2011). Agents are simulations of electrical power brokers, who must compete with each other for both power production and consumption, and manage their portfolios.

  12. Mediating Performance Through Virtual Agents

    OpenAIRE

    Giannachi, Gabriella; Gillies, Marco; Kaye, Nick; Swapp, David

    2009-01-01

    This paper presents the process of creation of virtual agents used in a virtual reality performance. The performance aimed to investigate how drama and performance could inform the creation of virtual agents and also how virtual reality could raise questions for drama and performance. The virtual agents were based on the performance of 2 actors. This paper describes the process of preparing the actors, capturing their performances and transferring them to the virtual agents. A second set of a...

  13. Erythropoietic Agents and the Elderly

    OpenAIRE

    Agarwal, Neeraj; Prchal, Josef T.

    2008-01-01

    Erythropoietin is a peptide hormone that stimulates erythropoiesis. There are several agents in clinical use and in development, which either act as ligands for the cell surface receptors of erythropoietin or promote erythropoietin production that stimulates erythropoiesis. These are known as erythropoietic agents. The agents already in use include epoetin alfa, epoetin beta, and darbepoetin alfa. Newer agents stimulating erythropoiesis (such as continuous erythropoietin receptor activator (C...

  14. Morphological transformations of silver nanoparticles in seedless photochemical synthesis

    Science.gov (United States)

    Lu, Ya; Zhang, Congyun; Hao, Rui; Zhang, Dongjie; Fu, Yizheng; Moeendarbari, Sina; Pickering, Christopher S.; Hao, Yaowu; Liu, Yaqing

    2016-05-01

    Photochemical synthesis is an easily controlled and reliable method for the fabrication of silver (Ag) nanoparticles with various morphologies. In this work, we have systematically investigated the seedless photochemical synthesis of anisotropic Ag nanoparticles with and without PVP as surface capping agent. The time evolution of anisotropic Ag nanoparticles during the synthesis process are studied using UV–visible spectra, optical images and transmission electron microscopy. The results show that the light irradiation precisely controls the start and termination of the reaction, and the presence or absence of PVP greatly affects the morphology evolution of anisotropic Ag nanoparticles. With PVP as the surface capping agent, Ag nanoparticles grow into decahedra or prism by the deposition of Ag atoms on {111} or {110} facets through epitaxial growth. However, a different morphology evolution could happen when Ag nanoparticle is synthesized without PVP as surface capping agent. In this case, Ag nanoparticles can fuse into the decahedrons through an edge-selective particle fusion mechanism, which involves attachment, rotation and realignment of Ag nanoparticles. This process was evidenced with HRTEM images at the different stages of the transformation from Ag colloid to decahedra nanoparticles. Oriented attachment and Ostwald ripening also play important role in the transformation process.

  15. 聚丙烯MI及成核剂添加量对TIPS法多孔膜结构与透过性能的影响%Effect of polypropylene MI and nucleating agent addition on morphology and permeability of porous membrane via TIPS method

    Institute of Scientific and Technical Information of China (English)

    杨振生; 张艳菊; 王志英; 崔东胜

    2011-01-01

    The behaviors of thermally induced phase separation for isotactic polypropylene (iPP) /di-n-butyl phthalate (DBP)/ dioctyl phthalate (DOP)/TM-1 systems are investigated. The iPP named F401 whose melt flow index (MI) is higher , and iPP named T30S whose MI is lower, are used in this work, respectively. Non-isothermal crystallization of iPP from the system is investigated using differential scanning calorimeter (DSC), and nucleation and spherulitic growth of iPP from the system are observed using optical microscopy as well. The iPP porous membranes are prepared by molding with heater and subsequently cooling. Then, the morphology, the permeability of the membrane are characterized. The results show that the nucleation activity of TM-1 to T30S/ DBP/DOP systems is higher than that of F4O1/DBP/DOP systems. Different type morphologies of porous membranes are obtained from iPP resins of different MI. Adding TM-1 to T30S/DBP/DOP, the morphology of the membrane changes from a close-knit spherulitic structure with cellular pores to an opened partly cellular structure with paniculate boundaries. By contraries, adding TM-1 to F401/DBP/DOP, the morphology of the membrane is a close-knit spherulitic structure with cellular pores, similar to that of none of TM-1, and the spherulitic size decreases with increasing TM -1 adding. At same TM -1 adding, the permeability of the membrane from T30S systems is higher than that of F401 systems.%研究了等规聚丙烯(iPP)/邻苯二甲酸二丁酯(DBP)/邻笨二甲酸二辛酯(DOP)/成核剂TM-1体系的热致相分离(TIPS)行为,采用熔融指数(MI)较低的聚丙烯T30S与MI较高的F401作对比研究.采用示差扫描量热仪(DSC)测定成核效应,采用光学显微镜观察iPP成核与晶粒生长.经过加热模压并控制冷却速率制备iPP多孔膜,对膜结构及其透过性能进行了表征.结果表明:相比于F401/DBP/DOP体系,TM-1对T30S/DBP/DOP体系表现出更强的成核效应;不同MI聚丙烯制备的多

  16. Cultural Differentiation of Negotiating Agents

    NARCIS (Netherlands)

    Hofstede, G.J.; Jonker, C.M.; Verwaart, D.

    2012-01-01

    Negotiations proceed differently across cultures. For realistic modeling of agents in multicultural negotiations, the agents must display culturally differentiated behavior. This paper presents an agent-based simulation model that tackles these challenges, based on Hofstede’s model of national cultu

  17. Cultural differentiation of negotiating agents

    NARCIS (Netherlands)

    Hofstede, G.J.; Jonker, C.M.; Verwaart, T.

    2010-01-01

    Negotiations proceed differently across cultures. For realistic modeling of agents in multicultural negotiations, the agents must display culturally differentiated behavior. This paper presents an agent-based simulation model that tackles these challenges, based on Hofstede’s model of national cultu

  18. Collaborating with Autonomous Agents

    Science.gov (United States)

    Trujillo, Anna C.; Cross, Charles D.; Fan, Henry; Hempley, Lucas E.; Motter, Mark A.; Neilan, James H.; Qualls, Garry D.; Rothhaar, Paul M.; Tran, Loc D.; Allen, B. Danette

    2015-01-01

    With the anticipated increase of small unmanned aircraft systems (sUAS) entering into the National Airspace System, it is highly likely that vehicle operators will be teaming with fleets of small autonomous vehicles. The small vehicles may consist of sUAS, which are 55 pounds or less that typically will y at altitudes 400 feet and below, and small ground vehicles typically operating in buildings or defined small campuses. Typically, the vehicle operators are not concerned with manual control of the vehicle; instead they are concerned with the overall mission. In order for this vision of high-level mission operators working with fleets of vehicles to come to fruition, many human factors related challenges must be investigated and solved. First, the interface between the human operator and the autonomous agent must be at a level that the operator needs and the agents can understand. This paper details the natural language human factors e orts that NASA Langley's Autonomy Incubator is focusing on. In particular these e orts focus on allowing the operator to interact with the system using speech and gestures rather than a mouse and keyboard. With this ability of the system to understand both speech and gestures, operators not familiar with the vehicle dynamics will be able to easily plan, initiate, and change missions using a language familiar to them rather than having to learn and converse in the vehicle's language. This will foster better teaming between the operator and the autonomous agent which will help lower workload, increase situation awareness, and improve performance of the system as a whole.

  19. Fish Manoeuvres and Morphology

    Science.gov (United States)

    Singh, Kiran; Pedley, Timothy

    2008-11-01

    The extraordinary manoeuvrability observed in many fish is attributed to their inherent flexibility, which might be enhanced by the use of appendages like fins. The aim of this work is to understand the role of morphological adaptations, such as body shape and deployment of median fins, on manoeuvrability and internal body dynamics. The 3d vortex lattice numerical method was employed to analyse the hydrodynamics for arbitrary body planforms of infinitesimal thickness. The internal structure of the body due to the combined skeletal system and soft tissue, is represented as an active Euler-Bernoulli beam, in which the time-dependent bending moment distribution is calculated from body inertia and the hydrodynamic pressure difference across the body. C-turns are the manoeuvre of choice for this work and the response for three different species of fish are examined. Angelfish(Pterophyllum eimekei), pike (Esox sp) and tuna (Thunnus albacares) were chosen for their differences in body profile, median fin use and manoeuvrability. Net direction change and bending moment response to prescribed backbone flexure are calculated and used to interpret the influence of body profile on manoeuvrability and muscle work done. Internal stresses may be computed from anatomical data on muscle fibre distribution and recruitment. To the future, it is intended to extend this work to other typical manoeuvres, such as fast starts for which muscle activation patterns have been measured quite widely.

  20. Morphology of Treponema pallidum.

    Science.gov (United States)

    Ovcinnikov, N M; Delektorskij, V V

    1966-01-01

    In recent years many investigations have been carried out on the morphology of Treponema pallidum by means of the electron microscope, and the use of ultra-thin sections has shown up a number of structural details. However, there is still need for much more evidence before the internal structure of treponemes can be elucidated fully and the functions of the structures interpreted. To provide such evidence, the authors have examined under the electron microscope negative-stained treponemes and ultra-thin sections, using both cultivated strains and treponemes obtained direct from syphilids in people suffering from fresh secondary syphilis. It has been shown that treponemes have a complex structure. T. pallidum has a two-layered outer wall, a cytoplasmic membrane proper, cytoplasm and a bunch of fibrils following a different path in different places on the treponeme. The sites of insertion of the fibrils (the basal granules) were investigated; structures similar to mesosomes and nucleoids were found. Cysts and granular forms are described. PMID:5332527

  1. Agentes de información Information Agents

    Directory of Open Access Journals (Sweden)

    Alfonso López Yepes

    2005-12-01

    Full Text Available Este artículo realiza un repaso sobre las tipologías de agentes de información y describe aspectos como movilidad, racionalidad y adaptatividad, y el ajuste final de estos conceptos a entornos distribuidos como Internet, donde este tipo de agentes tienen un amplio grado de aplicación. Asimismo, se propone una arquitectura de agentes para un sistema multiagente de recuperación de información donde se aplica un paradigma documental basado en el concepto de ciclo documental.This article summarizes the main information agent types reflecting on issues such as mobility, rationality, adaptability and the final adjustment of this concepts to distributed environments such as the Internet, where this kind of agents has wide range application. Likewise, an information agent architecture is proposed to create a multi-agent information retrieval system in which a documentary paradigm based on the documentary cycle is developed.

  2. Secure Mobile Trade Agent

    Directory of Open Access Journals (Sweden)

    Musbah M. Aqe

    2007-01-01

    Full Text Available E-commerce on the internet has the ability to produce millions of transactions and a great number of merchants whose supply merchandise over the internet. As a result, it is difficult for entities to roam over every site on the internet and choose the best merchandise to trade. So, in this paper we introduced a mobile trade agent that visit the sites to gather and evaluate the information from merchant servers and decide to trade goods on behalf of the user. We observed that the combination of public key cryptosystem with distributed object technology make this proposed scheme more secure and efficient than the already existed schemes.

  3. Configuring Computational Agents

    Czech Academy of Sciences Publication Activity Database

    Beuster, G.; Neruda, Roman

    Halifax : Saint Mary's University, 2004 - (Zhuge, H.; Cheung, W.; Liu, J.), s. 57-62 ISBN 0-9734039-8-5. [International Workshop on Knowledge Grid and Grid Intelligence /2./. Beijing (CN), 20.09.2004] R&D Projects: GA AV ČR 1ET100300419 Grant ostatní: CZ-DE project(XX) CZE-03/023 Institutional research plan: CEZ:AV0Z1030915 Keywords : Bang 3 * multi-agent systems * computational intelligence models Subject RIV: BA - General Mathematics

  4. Morphological knowledge and literacy acquisition.

    Science.gov (United States)

    Nagy, William E; Carlisle, Joanne F; Goodwin, Amanda P

    2014-01-01

    The purpose of this special issue of the Journal of Learning Disabilities is to bring to the attention of researchers and educators studies on morphology and literacy that either involve students with learning difficulties or have educational implications for teaching such students. In our introduction, we first provide background information about morphological knowledge and consider the role of morphology in literacy, focusing on findings that are relevant for instruction of students who struggle with reading and writing. Next we present an overview of the studies included in this issue, organized by current issues concerning the role of morphological knowledge in literacy. Collectively, the articles in this issue suggest that students with weaker literacy skills tend to lag behind their peers in morphological knowledge but that all students are likely to benefit from morphological instruction. Morphological interventions hold promise, especially for students who face challenges in language learning and literacy, but additional research is needed to provide a basis for informed decisions about the design of effective morphological interventions. PMID:24219917

  5. Holograms as Teaching Agents

    Science.gov (United States)

    Walker, Robin A.

    2013-02-01

    Hungarian physicist Dennis Gabor won the Pulitzer Prize for his 1947 introduction of basic holographic principles, but it was not until the invention of the laser in 1960 that research scientists, physicians, technologists and the general public began to seriously consider the interdisciplinary potentiality of holography. Questions around whether and when Three-Dimensional (3-D) images and systems would impact American entertainment and the arts would be answered before educators, instructional designers and students would discover how much Three-Dimensional Hologram Technology (3DHT) would affect teaching practices and learning environments. In the following International Symposium on Display Holograms (ISDH) poster presentation, the author features a traditional board game as well as a reflection hologram to illustrate conventional and evolving Three-Dimensional representations and technology for education. Using elements from the American children's toy Operation® (Hasbro, 2005) as well as a reflection hologram of a human brain (Ko, 1998), this poster design highlights the pedagogical effects of 3-D images, games and systems on learning science. As teaching agents, holograms can be considered substitutes for real objects, (human beings, organs, and animated characters) as well as agents (pedagogical, avatars, reflective) in various learning environments using many systems (direct, emergent, augmented reality) and electronic tools (cellphones, computers, tablets, television). In order to understand the particular importance of utilizing holography in school, clinical and public settings, the author identifies advantages and benefits of using 3-D images and technology as instructional tools.

  6. Amphoteric surface active agents

    Directory of Open Access Journals (Sweden)

    Eissa, A.M. F.

    1995-10-01

    Full Text Available 2-[trimethyl ammonium, triethyl ammonium, pyridinium and 2-amino pyridinium] alkanoates, four series of surface active agents containing carbon chain C12, C14, C16 and C18carbon atoms, were prepared. Their structures were characterized by microanalysis, infrared (IR and nuclear magnetic resonance (NMR. Surface and interfacial tension, Krafft point, wetting time, emulsification power, foaming height and critical micelle concentration (cmc were determined and a comparative study was made between their chemical structure and surface active properties. Antimicrobial activity of these surfactants was also determined.

    Se prepararon cuatro series de agentes tensioactivos del tipo 2-[trimetil amonio, trietil amonio, piridinio y 2-amino piridinio] alcanoatos, que contienen cadenas carbonadas con C12, C14, C16 y C18 átomos de carbono.
    Se determinaron la tensión superficial e interfacial, el punto de Krafft, el tiempo humectante, el poder de emulsionamiento, la altura espumante y la concentración critica de miscela (cmc y se hizo un estudio comparativo entre la estructura química y sus propiedades tensioactivas. Se determinó también la actividad antimicrobiana de estos tensioactivos. Estas estructuras se caracterizaron por microanálisis, infrarrojo (IR y resonancia magnética nuclear (RMN.

  7. Contrast agents for MRI

    International Nuclear Information System (INIS)

    Contrast agents are divided into two categories. The first one is paramagnetic compounds, including lanthanides like gadolinium, which mainly reduce the longitudinal (T1) relaxation property and result in a brighter signal. The second class consists of super-paramagnetic magnetic nanoparticles (SPMNPs) such as iron oxides, which have a strong effect on the transversal (T2) relaxation properties. SPMNPs have the potential to be utilized as excellent probes for magnetic resonance imaging (MRI). For instance, clinically benign iron oxide and engineered ferrite nanoparticles provide a good MRI probing capability for clinical applications. Furthermore, the limited magnetic property and inability to escape from the reticuloendothelial system (RES) of the used nanoparticles impede their further advancement. Therefore, it is necessary to develop the engineered magnetic nanoparticle probes for the next-generation molecular MRI. Considering the importance of MRI in diagnosing diseases, this paper presents an overview of recent scientific achievements in the development of new synthetic SPMNP probes whereby the sensitive and target-specific observation of biological events at the molecular and cellular levels is feasible. - Highlights: • This paper studies the contrast agents for MRI. • Fe―Co alloys and Mn-ferrites exhibit suitable contrast enhancement. • Nonhydrolytic thermal-decomposition synthetic method is suitable to produce MNPs. • This method allows controlling the size, magnetic dopants, magneto-crystalline anisotropy. • The increase in the superparamagnetic size leads to the contrast-enhancement

  8. Agent-oriented Software Engineering

    Institute of Scientific and Technical Information of China (English)

    GUAN Xu; CHENG Ming; LIU Bao

    2001-01-01

    An increasing number of computer systems are being viewed in terms of autonomous agents.Most people believe that agent-oriented approach is well suited to design and build complex systems. Yet. todate, little effort had been devoted to discuss the advantages of agent-oriented approach as a mainstreamsoftware engineering paradigm. Here both of this issues and the relation between object-oriented and agent-oriented will be argued. we describe an agent-oriented methodology and provide a quote for designing anauction system.

  9. Learning models of intelligent agents

    Energy Technology Data Exchange (ETDEWEB)

    Carmel, D.; Markovitch, S. [Computer Science Dept., Haifa (Israel)

    1996-12-31

    Agents that operate in a multi-agent system need an efficient strategy to handle their encounters with other agents involved. Searching for an optimal interactive strategy is a hard problem because it depends mostly on the behavior of the others. In this work, interaction among agents is represented as a repeated two-player game, where the agents` objective is to look for a strategy that maximizes their expected sum of rewards in the game. We assume that agents` strategies can be modeled as finite automata. A model-based approach is presented as a possible method for learning an effective interactive strategy. First, we describe how an agent should find an optimal strategy against a given model. Second, we present an unsupervised algorithm that infers a model of the opponent`s automaton from its input/output behavior. A set of experiments that show the potential merit of the algorithm is reported as well.

  10. Flexible, secure agent development framework

    Science.gov (United States)

    Goldsmith; Steven Y.

    2009-04-07

    While an agent generator is generating an intelligent agent, it can also evaluate the data processing platform on which it is executing, in order to assess a risk factor associated with operation of the agent generator on the data processing platform. The agent generator can retrieve from a location external to the data processing platform an open site that is configurable by the user, and load the open site into an agent substrate, thereby creating a development agent with code development capabilities. While an intelligent agent is executing a functional program on a data processing platform, it can also evaluate the data processing platform to assess a risk factor associated with performing the data processing function on the data processing platform.

  11. UTBot: A Virtual Agent Platform for Teaching Agent System Design

    Directory of Open Access Journals (Sweden)

    In-Cheol Kim

    2007-02-01

    Full Text Available We introduce UTBot, a virtual agent platform for teaching agent system design. UTBot implements a client for the Unreal Tournament game server and Gamebots system. It provides students with the basic functionality required to start developing their own intelligent virtual agents to play autonomously UT games. UTBot includes a generic agent architecture, CAA (Context-sensitive Agent Architecture, a domain-specific world model, a visualization tool, several basic strategies (represented by internal modes and internal behaviors, and skills (represented by external behaviors. The CAA architecture can support complex long-term behaviors as well as reactive short-term behaviors. It also realizes high context-sensitivity of behaviors. We also discuss our experience using UTBot as a pedagogical tool for teaching agent system design in undergraduate Artificial Intelligence course.

  12. Mushrooms as therapeutic agents

    Directory of Open Access Journals (Sweden)

    Sushila Rathee

    2012-04-01

    Full Text Available Mushrooms have been known for their nutritional and culinary values and used as medicines and tonics by humans for ages. In modern terms, they can be considered as functional foods which can provide health benefits beyond the traditional nutrients. There are monographs that cover the medicinal and healing properties of some individual traditional mushrooms. There has been a recent upsurge of interest in mushrooms not only as a health food which is rich in protein but also as a source of biologically active compounds of medicinal value which include complementary medicine/dietary supplements for anticancer, antiviral, hepatoprotective, immunopotentiating and hypocholesterolemic agents. However the mechanisms of the various health benefits of mushrooms to humans still require intensive investigation, especially given the emergence of new evidence of their health benefits. In the present paper the medicinal potential of mushrooms is being discussed.

  13. Microencapsulation of chemotherapeutic agents

    International Nuclear Information System (INIS)

    Mixing various amounts of chemotherapeutic agents such as cisplatinum, 5-fluorouracil, mitomycin-C, and adriamycin with polymers such as poly-d, 1-lactide, ethylhydroxyethylcellulose, and polycaprolactone, several kinds of microcapsules were made. Among them, microcapsule made from ethylhydroxyethylcellulose showed best yield. Under light microscopy, the capsules were observed as particles with refractive properties. For the basic toxicity test, intraarterial administration of cisplatinum was done in 6 adult mongrel dogs. Follow-up angiography was accomplished in 2 wk intervals for 6 wks. Despite no significant difference in the histopathological examination between the embolized and normal kidneys, follow-up angiogram showed atrophy of renal cortex and diminished numbers of arterial branches in the embolized kidneys. In order to identify the structural properties of microcapsules, and to determine the drug content and the rate of release, further experiment is thought to be necessary. (Author)

  14. Hepatocytes as Immunological Agents.

    Science.gov (United States)

    Crispe, Ian N

    2016-01-01

    Hepatocytes are targeted for infection by a number of major human pathogens, including hepatitis B virus, hepatitis C virus, and malaria. However, hepatocytes are also immunological agents in their own right. In systemic immunity, they are central in the acute-phase response, which floods the circulation with defensive proteins during diverse stresses, including ischemia, physical trauma, and sepsis. Hepatocytes express a variety of innate immune receptors and, when challenged with pathogen- or damage-associated molecular patterns, can deliver cell-autonomous innate immune responses that may result in host defense or in immunopathology. Important human pathogens have evolved mechanisms to subvert these responses. Finally, hepatocytes talk directly to T cells, resulting in a bias toward immune tolerance. PMID:26685314

  15. MORBIDITY AGENTS: A REVIEW

    Directory of Open Access Journals (Sweden)

    Shrivastava Neelesh

    2011-09-01

    Full Text Available This paper discuss on clinical representation of morbid jealousy which often termed delusional jealousy or ‘Othello Syndrome’ is a psychiatric condition where a lover believes against all reason and their beloved is being sexually unfaithful. Patients will be preoccupied with their partner’s perceived lack of sexual fidelity and will often behave in an unacceptable or extreme way as they endeavor to prove their ideas. Misuse of any psychomotor is an important association cause morbidity jealousy agents, like CNS stimulants that release the catecholamine, particularly dopamine, from pre synaptic terminals substance should be treated as a priority. Where higher levels of violence are reported Sildenafil may be useful as a diagnostic as well as therapeutic test in such cases .Many studies have shown an association between high alcohol consumption and developing morbid jealousy. Amphetamine-induced psychosis has been extensively studied because of its close resemblance to schizophrenia.

  16. Killer whale morphology - Variation in morphology of killer whale ecotypes

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — We are using elliptic Fourier analysis to determine the patterns of variation in morphology of dorsal fin shape, saddle patch shape, and eye patch shape of...

  17. Agent Assignment for Process Management: Pattern Based Agent Performance Evaluation

    Science.gov (United States)

    Jablonski, Stefan; Talib, Ramzan

    In almost all workflow management system the role concept is determined once at the introduction of workflow application and is not reevaluated to observe how successfully certain processes are performed by the authorized agents. This paper describes an approach which evaluates how agents are working successfully and feed this information back for future agent assignment to achieve maximum business benefit for the enterprise. The approach is called Pattern based Agent Performance Evaluation (PAPE) and is based on machine learning technique combined with post processing technique. We report on the result of our experiments and discuss issues and improvement of our approach.

  18. Morphological control of layered double hydroxide through a biomimetic approach using carboxylic and sulfonic acids

    Directory of Open Access Journals (Sweden)

    Taishi Yokoi

    2015-09-01

    Full Text Available Layered double hydroxides (LDHs have intercalation properties and are used in various applications. The performances of the LDH materials can be improved by controlling crystal morphology. Morphology of inorganic crystals is controlled by organic molecules in biomineralization. Inspired by biomineralization, we investigated the effect of the addition of mono, di and triacids as morphological control agents on crystal morphology of LDH synthesized by the homogeneous precipitation method. Morphology of LDH was changed from hexagonal plate to stacked disc by addition of monoacids, namely acetic acid and methanesulfonic acid, in the reaction solution. Flower-shaped LDH crystals were formed in the presence of diacids and a triacid, namely succinic acid, 1,2-ethanedisulfonic acid and 1,2,3-propanetricarboxylic acid. We found that the morphology of the LDH crystals was controlled by the number of functional group on the morphological control agent rather than the type of functional group. These findings can contribute for the development of novel and functional LDH materials with precisely controlled morphology.

  19. Tuning the crystal morphology and size of zeolitic imidazolate framework-8 in aqueous solution by surfactants

    KAUST Repository

    Pan, Yichang

    2011-01-01

    Herein we report a facile synthesis method using surfactant cetyltrimethylammonium bromide (CTAB) as a capping agent for controlling the crystal size and morphology of zeolitic imidazolate framework-8 (ZIF-8) crystals in aqueous systems. The particle sizes can be precisely adjusted from ca. 100 nm to 4 μm, and the morphology can be changed from truncated cubic to rhombic dodecahedron. This journal is © The Royal Society of Chemistry.

  20. Our Experience with Two Cardioplegic Solutions: Dextrose versus Non-Dextrose in Adult Cardiac Surgery

    OpenAIRE

    Lessen, Ronald; DiCapua, John; Pekmezaris, Renee; Walia, Rajni; Bocchieri, Karl; Jahn, Lynda; Akerman, Meredith; Lesser, Martin L.; Hartman, Alan

    2012-01-01

    Intraoperative hyperglycemia has been observed to be associated with increased morbidity and mortality after cardiac surgery. Dextrose cardioplegia is used for its cardioprotective effects but may lead to intraoperative hyperglycemia and more postoperative complications. This was a retrospective observational study. Patient records (n = 2301) were accessed from a large database at a tertiary care facility. The two groups (dextrose vs. nondextrose) were then matched using preoperative variable...

  1. Odor Classification using Agent Technology

    Directory of Open Access Journals (Sweden)

    Sigeru OMATU

    2014-03-01

    Full Text Available In order to measure and classify odors, Quartz Crystal Microbalance (QCM can be used. In the present study, seven QCM sensors and three different odors are used. The system has been developed as a virtual organization of agents using an agent platform called PANGEA (Platform for Automatic coNstruction of orGanizations of intElligent Agents. This is a platform for developing open multi-agent systems, specifically those including organizational aspects. The main reason for the use of agents is the scalability of the platform, i.e. the way in which it models the services. The system models functionalities as services inside the agents, or as Service Oriented Approach (SOA architecture compliant services using Web Services. This way the adaptation of the odor classification systems with new algorithms, tools and classification techniques is allowed.

  2. Stability of Evolving Agent Populations

    CERN Document Server

    Briscoe, G

    2007-01-01

    Stability is perhaps the most desired feature in the systems that we design. It is important for us to be able to predict the response of a Multi-Agent System (MAS) to various environmental conditions prior to its actual deployment. The Chli-DeWilde agent stability measure views a MAS as a discrete time Markov chain with a potentially unknown transition probabilities. A MAS is considered to be stable when its state, a stochastic process, has converged to an equilibrium distribution. We investigate an extension of their agent stability definition to include MASs with evolutionary dynamics, focusing on evolving agent populations. Additionally, using our extended agent stability measure, we construct an entropy-based definition for the degree of instability. An example system, the Digital Ecosystem, is considered in detail to investigate the stability of an evolving agent population through simulations. The results are consistent with the original Chli-DeWilde measure.

  3. Agent-based enterprise integration

    Energy Technology Data Exchange (ETDEWEB)

    N. M. Berry; C. M. Pancerella

    1998-12-01

    The authors are developing and deploying software agents in an enterprise information architecture such that the agents manage enterprise resources and facilitate user interaction with these resources. The enterprise agents are built on top of a robust software architecture for data exchange and tool integration across heterogeneous hardware and software. The resulting distributed multi-agent system serves as a method of enhancing enterprises in the following ways: providing users with knowledge about enterprise resources and applications; accessing the dynamically changing enterprise; locating enterprise applications and services; and improving search capabilities for applications and data. Furthermore, agents can access non-agents (i.e., databases and tools) through the enterprise framework. The ultimate target of the effort is the user; they are attempting to increase user productivity in the enterprise. This paper describes their design and early implementation and discusses the planned future work.

  4. Mobile Agents for Digital Signage

    OpenAIRE

    SATOH, Ichiro

    2010-01-01

    International audience This paper presents an agent-based framework for building and operating context-aware multimedia content on digital signage in public/private spaces. It enables active and multimedia content to be composed from mobile agents, which can travel from computer to computer and provide multimedia content for advertising or user-assistant services to users. The framework automatically deploys their agents at computers near to their current positions to provide advertising o...

  5. An agent for ecological deliberation

    OpenAIRE

    Debenham, John; Sierra, Carles

    2010-01-01

    An agent architecture supports the two forms of deliberation used by human agents. Cartesian, constructivist rationalism leads to game theory, decision theory and logical models. Ecological rationalism leads to deliberative actions that are derived from agents’ prior interactions and are not designed; i.e., they are strictly emergent. This paper aims to address the scant attention paid by the agent community to the predominant form of deliberation used by mankind.

  6. Agent factory: towards social robots

    OpenAIRE

    O'Hare, G. M. P.; Duffy, Brian R.; Collier, Rem; Rooney, Colm, (Thesis); O'Donoghue, Ruadhan

    1999-01-01

    This paper advocates the application of multi-agent techniques in the realisation of social robotic behaviour. We present the Social Robot Architecture, which integrates the key elements of agent-hood and robotics in a coherent and systematic manner. This architecture seamlessly integrates, real world robots, multi-agent development tools, and VRML visualisation tools into a coherent whole. Using these elements, we deliver a development environment, which facilitates rapid prototyping of soci...

  7. Agent Systems in Software Engineering

    OpenAIRE

    Lazarou, Vasilios S.; Gardikiotis, Spyridon K.; Malevris, Nicos

    2008-01-01

    In this chapter, the application of multi-agent systems to tackle the software engineering task was outlined. The concentration was on the employment of agent technology in order to deal with distributed software systems and mainly distributed database applications and web applications. The rationale behind utilizing agent technology has to do with the multi-tier architecture and the associated inherent complication of distributed applications and the required interoperability of software res...

  8. Research on Negotiating Agent Development

    Institute of Scientific and Technical Information of China (English)

    WEI Ding-guo; PENG Hong

    2004-01-01

    The paper presents a flexible and effective method of development of negotiating agents.A strategy specification, which is specified by a state chart and defeasible rules, can be dynamically inserted into an agent shell incorporating a state chart interpreter and a defeasible logic inference engine, in order to yield a desirable agent.The set of desirable criteria and rules is required to be justified with different context of the application.

  9. Extending Agent Languages for Autonomy

    OpenAIRE

    Meneguzzi, Felipe Rech

    2008-01-01

    BDI agent languages provide a useful abstraction for complex systems comprised of interactive autonomous entities, but they have been used mostly in the context of single agents with a static plan library of behaviours invoked reactively. These languages provide a theoretically sound basis for agent design but are very limited in providing direct support for autonomy and societal cooperation needed for large scale systems. Some techniques for autonomy and cooperation have been explored in the...

  10. Radioactive scanning agents with stabilizer

    International Nuclear Information System (INIS)

    Stable compositions useful as technetium 99-based scintigraphic agents comprise gentisyl alcohol or a pharmaceutically-acceptable salt or ester thereof in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (sup(99m)TcOsub(4)sup(-)) solution. The compositions are especially useful in combination with a phosphate or phosphonate material that carries the radionuclide to bone, thus providing a skeletal imaging agent

  11. Mathematical morphology for shape description

    Science.gov (United States)

    Schmitt, M.

    2002-03-01

    We first examine the measurements one can perform on the space of compact and convex sets. A famous theorem, due to Hadwiger (1957), shows that any measurement with nice properties, namely additivity, is a linear combination of Minkowski functionals. Then, some useful formulae, linking measurements in different dimensions of space are derived.In the second step, we make use of the morphological operations transforming sets into sets. These sets are then measured using the previous measurements. The most famous attempt yields the concept of granulomerties and their extensions.In the last part, we examine a way to build morphological random sets which are compatible with morphological operators like erosions or openings and apply it to the most famous example in morphology, the Boolean model, describing objects located at random.

  12. Technetium diagnostic agent and carrier

    International Nuclear Information System (INIS)

    A stable sup(99m)Tc-labelled radioactive diagnostic agent is produced by contacting sup(99m)Tc-containing pertechnetate with a non-radioactive carrier comprising a chelating agent, a water-soluble reducing agent and a stabilizer. The stabilizer is chosen from ascorbic acid and erythorbic acid and their pharmaceutically acceptable salts and esters. A mole ratio of more than 100 moles ascorbic or erythorbic acid to 1 mole of reducing agent provides a stable composition at high levels of radioactivity

  13. Relational agents: A critical review

    DEFF Research Database (Denmark)

    Campbell, Robert H.; Grimshaw, Mark Nicholas; Green, Gill

    2009-01-01

    and non-player characters that can actively participate in such relationships. The focus of this review is relational agents, agents that can build long term socioemotional relationships with users. In virtual worlds, such agents are just starting to emerge; they are more common in other environments...... but remain few and far between. This review critically assesses the progress of relational agent development and research since their inception in 2005, proposes new areas of research and considers the potential for their exploitation in virtual worlds....

  14. Mitochondrial morphology and cardiovascular disease

    OpenAIRE

    Ong, Sang-Bing; Hausenloy, Derek J

    2010-01-01

    Mitochondria are dynamic and are able to interchange their morphology between elongated interconnected mitochondrial networks and a fragmented disconnected arrangement by the processes of mitochondrial fusion and fission, respectively. Changes in mitochondrial morphology are regulated by the mitochondrial fusion proteins (mitofusins 1 and 2, and optic atrophy 1) and the mitochondrial fission proteins (dynamin-related peptide 1 and mitochondrial fission protein 1) and have been implicated in a...

  15. Incorporating BDI Agents into Human-Agent Decision Making Research

    Science.gov (United States)

    Kamphorst, Bart; van Wissen, Arlette; Dignum, Virginia

    Artificial agents, people, institutes and societies all have the ability to make decisions. Decision making as a research area therefore involves a broad spectrum of sciences, ranging from Artificial Intelligence to economics to psychology. The Colored Trails (CT) framework is designed to aid researchers in all fields in examining decision making processes. It is developed both to study interaction between multiple actors (humans or software agents) in a dynamic environment, and to study and model the decision making of these actors. However, agents in the current implementation of CT lack the explanatory power to help understand the reasoning processes involved in decision making. The BDI paradigm that has been proposed in the agent research area to describe rational agents, enables the specification of agents that reason in abstract concepts such as beliefs, goals, plans and events. In this paper, we present CTAPL: an extension to CT that allows BDI software agents that are written in the practical agent programming language 2APL to reason about and interact with a CT environment.

  16. Effect of lactic acid on nucleation morphology and surface roughness of electroless Ni–P deposition in nanoscale

    Indian Academy of Sciences (India)

    A Babanejhad; M Hashemi; Y Rahmatallahpur; Sh A Nozad

    2012-08-01

    The present work aims to study effect of lactic acid concentration as complexing agent on surface roughness and nucleation morphology of electroless N–P deposition. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) have been used to study nucleation morphology and surface roughness of deposition. Deposition process started at some initial priority growing centres independently distributed on the substrate. We found that the morphology and surface roughness of deposition strongly depends on the complexing agent concentration. Morphology of initial deposited centres with no concentration of lactic acid was in coniform structure. By increasing the complexing agent concentration, the structure of initial growing centres changed from coniform to nodular shape and the surface roughness of depositions decreased.

  17. Plasmids encoding therapeutic agents

    Science.gov (United States)

    Keener, William K.

    2007-08-07

    Plasmids encoding anti-HIV and anti-anthrax therapeutic agents are disclosed. Plasmid pWKK-500 encodes a fusion protein containing DP178 as a targeting moiety, the ricin A chain, an HIV protease cleavable linker, and a truncated ricin B chain. N-terminal extensions of the fusion protein include the maltose binding protein and a Factor Xa protease site. C-terminal extensions include a hydrophobic linker, an L domain motif peptide, a KDEL ER retention signal, another Factor Xa protease site, an out-of-frame buforin II coding sequence, the lacZ.alpha. peptide, and a polyhistidine tag. More than twenty derivatives of plasmid pWKK-500 are described. Plasmids pWKK-700 and pWKK-800 are similar to pWKK-500 wherein the DP178-encoding sequence is substituted by RANTES- and SDF-1-encoding sequences, respectively. Plasmid pWKK-900 is similar to pWKK-500 wherein the HIV protease cleavable linker is substituted by a lethal factor (LF) peptide-cleavable linker.

  18. Gastrointestinal scanning agent

    International Nuclear Information System (INIS)

    An easily prepared radiolabeled gastrointestinal scanning agent is described. Technetium-99m has ideal characteristics for imaging the upper and lower GI tract and determining stomach emptying and intestinal transit time when used with an insoluble particulate material. For example, crystalline and amorphous calcium phosphate particles can be effectively labeled in a one-step process using sup(99m)TcO4 and SnCl2. These labeled particles have insignificant mass and when administered orally pass through the GI tract unchanged, without affecting the handling and density of the intestinal contents. Visualization of the esophageal entry into the stomach, the greater and lesser curvatures of the stomach, ejection into the duodenum, and rates of passage through the upper and lower GI tract are obtained. The slurry of sup(99m)TC particulate can be given rectally by enema. Good images of the cecum and the ascending, transverse, and descending colon are obtained. Mucosal folds and the splenic and hepatic flexures are visualized. The resilience of the large intestine is also readily visualized by pneumocolonographic techniques. (author)

  19. Liposomal encapsulation enhances the antitumour efficacy of the vascular disrupting agent ZD6126 in murine B16.F10 melanoma

    OpenAIRE

    Fens, M H A M; Hill, K. J.; Issa, J; Ashton, S E; Westwood, F. R.; Blakey, D C; Storm, G; Ryan, A J; Schiffelers, R.M.

    2008-01-01

    Vascular disrupting agents (VDAs) are able to affect selectively tumour endothelial cell morphology resulting in vessel occlusion and widespread tumour cell necrosis. However, single-agent antitumour activity of VDAs is typically limited, as tumour regrowth occurs rapidly following drug treatment. To improve the therapeutic effectiveness of VDAs, we investigated liposomal targeting using ZD6126 as a model VDA. ZD6126 is a phosphate-prodrug of the tubulin-binding vascular disrupting agent ZD61...

  20. Multiwalled carbon nanotube hybrids as MRI contrast agents.

    Science.gov (United States)

    Kuźnik, Nikodem; Tomczyk, Mateusz Michał

    2016-01-01

    Magnetic resonance imaging (MRI) is one of the most commonly used tomography techniques in medical diagnosis due to the non-invasive character, the high spatial resolution and the possibility of soft tissue imaging. Contrast agents, such as gadolinium complexes and superparamagnetic iron oxides, are administered to spotlight certain organs and their pathologies. Many new models have been proposed that reduce side effects and required doses of these already clinically approved contrast agents. These new candidates often possess additional functionalities, e.g., the possibility of bioactivation upon action of particular stimuli, thus serving as smart molecular probes, or the coupling with therapeutic agents and therefore combining both a diagnostic and therapeutic role. Nanomaterials have been found to be an excellent scaffold for contrast agents, among which carbon nanotubes offer vast possibilities. The morphology of multiwalled carbon nanotubes (MWCNTs), their magnetic and electronic properties, the possibility of different functionalization and the potential to penetrate cell membranes result in a unique and very attractive candidate for a new MRI contrast agent. In this review we describe the different issues connected with MWCNT hybrids designed for MRI contrast agents, i.e., their synthesis and magnetic and dispersion properties, as well as both in vitro and in vivo behavior, which is important for diagnostic purposes. An introduction to MRI contrast agent theory is elaborated here in order to point to the specific expectations regarding nanomaterials. Finally, we propose a promising, general model of MWCNTs as MRI contrast agent candidates based on the studies presented here and supported by appropriate theories. PMID:27547627

  1. 2012 Survey of clothing agents

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Clothing agents take part in China International Clothing and Accessories Fairs ( CHIC ) year by year. In order to attracting investment, they compared with each other at improving their originality and service levels. At the exhibition brands manufacturers and agents had a face-to-face communication,

  2. Topical agents in burn care

    Directory of Open Access Journals (Sweden)

    Momčilović Dragan

    2002-01-01

    Full Text Available Introduction Understanding of fluid shifts and recognition of the importance of early and appropriate fluid replacement therapy have significantly reduced mortality in the early post burn period. After the bum patient successfully passes the resuscitation period, the burn wound represents the greatest threat to survival. History Since the dawn of civilization, man has been trying to find an agent which would help burn wounds heal, and at the same time, not harm general condition of the injured. It was not until the XX century, after the discovery of antibiotics, when this condition was fulfilled. In 1968, combining silver and sulfadiazine, fox made silver-sulfadiazine, which is a 1% hydro-soluble cream and a superior agent in topical treatment of burns today. Current topical agents None of the topical antimicrobial agents available today, alone or combined, have the characteristics of ideal prophylactic agents, but they eliminate colonization of burn wound, and invasive infections are infrequent. With an excellent spectrum of activity, low toxicity, and ease of application with minimal pain, silver-sulfadiazine is still the most frequently used topical agent. Conclusion The incidence of invasive infections and overall mortality have been significantly reduced after introduction of topical burn wound antimicrobial agents into practice. In most burn patients the drug of choice for prophylaxis is silver sulfadiazine. Other agents may be useful in certain clinical situations.

  3. Agent Roles in Human Teams

    OpenAIRE

    Lewis, M.; Sycara, K.; Payne, T.R.

    2003-01-01

    In this paper, we describe results of a series of experiments investigating the effects of agent aiding on human teams. The role an agent played, its task, and the ease with which it communicated with its human teammates all influenced team behavior. Team supporting tasks such as relaying and reminding seemed particularly effective.

  4. Intelligent Agents in Physics Education

    Science.gov (United States)

    Sánchez-Guzmán, D.; Mora, César

    2010-07-01

    Intelligent Agents are being applied in a wide range of processes and everyday applications. Their development is not new, in recent years they have had an increased attention and design; like learning and mentoring tools. In this work we discuss the definition of what an intelligent agent is; how they are applied; how they look like; recent implementations of agents; agents as support in the learning process, more precisely intelligent tutors; their state in Latin-American countries and future developments and trends that will permit a better communication between people and agents. Also we present an Intelligent Tutor applied as a tool for improving high-school students' skills and reasoning for the first five topics of Mechanics curricula.

  5. Markov Tracking for Agent Coordination

    Science.gov (United States)

    Washington, Richard; Lau, Sonie (Technical Monitor)

    1998-01-01

    Partially observable Markov decision processes (POMDPs) axe an attractive representation for representing agent behavior, since they capture uncertainty in both the agent's state and its actions. However, finding an optimal policy for POMDPs in general is computationally difficult. In this paper we present Markov Tracking, a restricted problem of coordinating actions with an agent or process represented as a POMDP Because the actions coordinate with the agent rather than influence its behavior, the optimal solution to this problem can be computed locally and quickly. We also demonstrate the use of the technique on sequential POMDPs, which can be used to model a behavior that follows a linear, acyclic trajectory through a series of states. By imposing a "windowing" restriction that restricts the number of possible alternatives considered at any moment to a fixed size, a coordinating action can be calculated in constant time, making this amenable to coordination with complex agents.

  6. Chemotherapy-induced pulmonary hypertension: role of alkylating agents.

    Science.gov (United States)

    Ranchoux, Benoît; Günther, Sven; Quarck, Rozenn; Chaumais, Marie-Camille; Dorfmüller, Peter; Antigny, Fabrice; Dumas, Sébastien J; Raymond, Nicolas; Lau, Edmund; Savale, Laurent; Jaïs, Xavier; Sitbon, Olivier; Simonneau, Gérald; Stenmark, Kurt; Cohen-Kaminsky, Sylvia; Humbert, Marc; Montani, David; Perros, Frédéric

    2015-02-01

    Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension (PH) characterized by progressive obstruction of small pulmonary veins and a dismal prognosis. Limited case series have reported a possible association between different chemotherapeutic agents and PVOD. We evaluated the relationship between chemotherapeutic agents and PVOD. Cases of chemotherapy-induced PVOD from the French PH network and literature were reviewed. Consequences of chemotherapy exposure on the pulmonary vasculature and hemodynamics were investigated in three different animal models (mouse, rat, and rabbit). Thirty-seven cases of chemotherapy-associated PVOD were identified in the French PH network and systematic literature analysis. Exposure to alkylating agents was observed in 83.8% of cases, mostly represented by cyclophosphamide (43.2%). In three different animal models, cyclophosphamide was able to induce PH on the basis of hemodynamic, morphological, and biological parameters. In these models, histopathological assessment confirmed significant pulmonary venous involvement highly suggestive of PVOD. Together, clinical data and animal models demonstrated a plausible cause-effect relationship between alkylating agents and PVOD. Clinicians should be aware of this uncommon, but severe, pulmonary vascular complication of alkylating agents. PMID:25497573

  7. Phytoconstituents as apoptosis inducing agents: strategy to combat cancer.

    Science.gov (United States)

    Kumar, Manish; Kaur, Varinder; Kumar, Subodh; Kaur, Satwinderjeet

    2016-08-01

    Advancement in the field of cancer molecular biology has aided researchers to develop various new chemopreventive agents which can target cancer cells exclusively. Cancer chemopreventive agents have proficiency to inhibit, reverse and delay process of carcinogenesis during its early and later course. Chemopreventive agents can act as antioxidative, antimutagenic/antigenotoxic, anti-inflammatory agents or via aiming various molecular targets in a cell to induce cell death. Apoptosis is a kind of cell death which shows various cellular morphological alterations such as cell shrinkage, blebbing of membrane, chromatin condensation, DNA fragmentation, formation of apoptotic bodies etc. Nowadays, apoptosis is being one of the new approaches for the identification and development of novel anticancer therapies. For centuries, plants are known to play part in daily routine from providing food to management of human health. In the last two decades, diverse phytochemicals and various botanical formulations have been characterized as agents that possess potential to execute cancer cells via inducing apoptosis. Data obtained from the research carried out globally pointed out that natural products are the potential candidates which have capability to combat cancer. In the present review, we surveyed literature on natural products which throws light on the mechanism through which these phytochemicals induce apoptosis in cancer cells. PMID:26239338

  8. Fuzzy Morphological Polynomial Image Representation

    Directory of Open Access Journals (Sweden)

    Chin-Pan Huang

    2010-01-01

    Full Text Available A novel signal representation using fuzzy mathematical morphology is developed. We take advantage of the optimum fuzzy fitting and the efficient implementation of morphological operators to extract geometric information from signals. The new representation provides results analogous to those given by the polynomial transform. Geometrical decomposition of a signal is achieved by windowing and applying sequentially fuzzy morphological opening with structuring functions. The resulting representation is made to resemble an orthogonal expansion by constraining the results of opening to equate adapted structuring functions. Properties of the geometric decomposition are considered and used to calculate the adaptation parameters. Our procedure provides an efficient and flexible representation which can be efficiently implemented in parallel. The application of the representation is illustrated in data compression and fractal dimension estimation temporal signals and images.

  9. Agent Communications using Distributed Metaobjects

    Energy Technology Data Exchange (ETDEWEB)

    Goldsmith, Steven Y.; Spires, Shannon V.

    1999-06-10

    There are currently two proposed standards for agent communication languages, namely, KQML (Finin, Lobrou, and Mayfield 1994) and the FIPA ACL. Neither standard has yet achieved primacy, and neither has been evaluated extensively in an open environment such as the Internet. It seems prudent therefore to design a general-purpose agent communications facility for new agent architectures that is flexible yet provides an architecture that accepts many different specializations. In this paper we exhibit the salient features of an agent communications architecture based on distributed metaobjects. This architecture captures design commitments at a metaobject level, leaving the base-level design and implementation up to the agent developer. The scope of the metamodel is broad enough to accommodate many different communication protocols, interaction protocols, and knowledge sharing regimes through extensions to the metaobject framework. We conclude that with a powerful distributed object substrate that supports metaobject communications, a general framework can be developed that will effectively enable different approaches to agent communications in the same agent system. We have implemented a KQML-based communications protocol and have several special-purpose interaction protocols under development.

  10. Mobile agent driven by aspect

    Directory of Open Access Journals (Sweden)

    Youssef Hannad

    2010-11-01

    Full Text Available Domain application of mobile agents is quite large. They are used for network management and the monitoring of complex architecture. Mobile agent is also essential into specific software architecture such that adaptable grid architecture. Even if the concept of mobile agent seems to be obvious, the development is always complex because it needs to understand network features but also security features and negotiation algorithms. We present a work about an application of aspects dedicated to mobile agent development over a local network. At this level, the underlying protocol is called jini and allows managing several essential concepts such that short transaction and permission management. Three subsets of aspects are defined in this work. A part is for the description of agent host and its security level, accessible resource, etc. A second part is about mobile agent and their collaboration. This means how they can operate on an agent host with the respect of the execution context. All the results are illustrated through a distributed monitoring application called DMA. Its main objective is the observation of component servers.

  11. Morphology of polymer solar cells

    DEFF Research Database (Denmark)

    Böttiger, Arvid P.L.

    the morphology of the active layer of the solar cells when produced with water based inks using R2R coating. Using a broad range of scattering and imaging techniques, cells coated with water based inks were investigated, and compared to their spin coated counterpart. Two challenges to be addressed were small...... as a function of polymer, type of ink, annealing etc. Ptychography is a new state of the art X-ray imaging technique based on coherent scattering. Together with Scanning X-ray Transmission Microscopy (STXM) it has been used in this study to inspect the morphology of the active layer taken from working solar...

  12. Intelligent Farmer Agent for Multi-Agent Ecological Simulations Optimization

    OpenAIRE

    Filipe Cruz; António Pereira; Pedro Valente; Pedro Duarte; Luis Paulo Reis

    2007-01-01

    This paper presents the development of a bivalve farmer agent interacting with a realistic ecological simulation system. The purpose of the farmer agent is to determine the best combinations of bivalve seeding areas in a large region, maximizing the production without exceeding the total allowed seeding area. A system based on simulated annealing, tabu search, genetic algorithms and reinforcement learning, was developed to minimize the number of iterations required to unravel a semi-optimum s...

  13. MDE and Mobile Agents : another reflexion on the agent migration

    OpenAIRE

    Gherbi, Tahar; Borne, Isabelle; Meslati, Djamel

    2009-01-01

    International audience Model Driven Engineering (MDE) is a software development approach family based on the use of models in the software construction. It allows the exploitation of models to simulate, estimate, understand, communicate and produce code. Mobile agents are a very interesting technology to develop applications for mobile and distributed environments. A mobile agent is essentially a computer program that acts autonomously on behalf of a user and travels through a network of h...

  14. Knowledge mining using intelligent agents

    CERN Document Server

    Dehuri, Satchidananda

    2010-01-01

    ""Knowledge Mining Using Intelligent Agents"" explores the concept of knowledge discovery processes and enhances decision-making capability through the use of intelligent agents like ants, termites and honey bees. In order to provide readers with an integrated set of concepts and techniques for understanding knowledge discovery and its practical utility, this book blends two distinct disciplines - data mining and knowledge discovery process, and intelligent agents-based computing (swarm intelligence and computational intelligence). For the more advanced reader, researchers, and decision/policy

  15. Agent-oriented Software Engineering

    Institute of Scientific and Technical Information of China (English)

    MingCheng; XuGuan; BaoLiu

    2004-01-01

    An increasing number of computer systems are being viewed in terms of autonomous agents.Most people believe that agent-oriented approach is well suited to designing and building complex systems. Yet, to date, little effort had been devoted to discussing the advantages of agent-oriented approach as a mainstream software engineering paradiam.Here both of this issues and the relation between object-oriented and agentoriented will be argued.We describe an agent-oriented methodology and provide a quote for designing a auction system.

  16. Can Ionic Liquids Be Used As Templating Agents For Controlled Design of Uranium-Containing Nanomaterials?

    Energy Technology Data Exchange (ETDEWEB)

    Visser, A.; Bridges, N.; Tosten, M.

    2013-04-09

    Nanostructured uranium oxides have been prepared in ionic liquids as templating agents. Using the ionic liquids as reaction media for inorganic nanomaterials takes advantage of the pre-organized structure of the ionic liquids which in turn controls the morphology of the inorganic nanomaterials. Variation of ionic liquid cation structure was investigated to determine the impact on the uranium oxide morphologies. For two ionic liquid cations, increasing the alkyl chain length increases the aspect ratio of the resulting nanostructured oxides. Understanding the resulting metal oxide morphologies could enhance fuel stability and design.

  17. Synthesis of Silver Nanoparticle and Its Morphological Control

    Institute of Scientific and Technical Information of China (English)

    WANG Xiang-rong; ZHENG Min; XU Jian; WANG Chang-ping

    2009-01-01

    Silver nanoparticles with different morphologies were prepared in AgNO3 aqueous solution using nanocarbon as template medium and polymer surfactant as protecting agent in an ultrasonic field. The polymer surfactant polyvinylpyrrolidone ( PVP) was self-prepared and used directly in aqueous solution form. The molecular weight of PVP was measured by viscosimeter. The crystalline phase,component, size, and morphology of the as-synthesized silver naoparticles were characterized by XRD, TEM,FTIR, and Laser Granularity Instrument. The results indicated that ultrasonic was the key factor to deoxidize Ag+to be Ag°nanocarbon and polymer surfactants accelerated the deoxidization reaction course and controlled the agglomeration of freshly formed silver nanoparticles, the category of polymer surfactant had decisive effect on the morphology of as-synthesized nanoparticle. Well-defined dendrites silver nanoparticle could be attained when choosing PVP as surfactant in AgNO3 aqueous solution,while regular sphere silver nanoparticle could be synthesized in the presence of polyvinyl alcohol (PVA) surfactant.Moreover, the concentration of AgNO3 and ultrasonic action time also had obvious effect on the morphology of silver nanoparticle, low concentration of AgNO3 and long time of ultrasonic were not in favor of forming dendrite silver.

  18. Planar SERS nanostructures with stochastic silver ring morphology for biosensor chips

    DEFF Research Database (Denmark)

    Semenova, Anna; Goodilin, Eugene; Brazhe, Nadezda;

    2012-01-01

    successful solution, a new effortless chemical approach to the design of nanostructured silver and heterometallic continuous coatings with a stochastic ‘‘coffee ring’’ morphology. The coatings are formed from an ultrasonic mist of aqueous diamminesilver hydroxide, free of reducing agents and nonvolatile......, thus making the substrates promising for various biosensor chips. Introduction...

  19. Optimistic Agents are Asymptotically Optimal

    OpenAIRE

    Sunehag, Peter; Hutter, Marcus

    2012-01-01

    We use optimism to introduce generic asymptotically optimal reinforcement learning agents. They achieve, with an arbitrary finite or compact class of environments, asymptotically optimal behavior. Furthermore, in the finite deterministic case we provide finite error bounds.

  20. Agents containing chlorhexidine in dentistry

    OpenAIRE

    Lebedeva S.N.; Zemlyanichenko М.К.

    2011-01-01

    Aclinical definition of the efficacy of chlorhexidine-containing means for reducing the risk of dental caries and gingivitis with plastic caps. Chlorhexidine is an effective antimicrobial agent for the formation of individual programs for the prevention of dental caries

  1. Chemical Agents: Facts about Evacuation

    Science.gov (United States)

    ... Health Emergency Response Guide Reaching At-Risk Populations Chemical Agents: Facts About Evacuation Format: Select one PDF [ ... on Facebook Tweet Share Compartir Some kinds of chemical accidents or attacks, such as a train derailment ...

  2. Morphology stabilization of heterogeneous blends

    International Nuclear Information System (INIS)

    A heterogeneous elastomer blend is described, consisting of at least two elastomer components which are cross-linkable by irradiation and having a stabilized morphology formed by subjecting the blend to high energy radiation to a point from below to slightly above the gel dose of the blend. (author)

  3. Craniofacial morphology in Muenke syndrome

    DEFF Research Database (Denmark)

    Keller, Mette Kirstine; Hermann, Nuno V; Darvann, Tron A; Larsen, Per; Hove, Hanne D; Christensen, Leif; Schwartz, Marianne; Marsh, Jeffrey L; Kreiborg, Sven

    2007-01-01

    corresponding to bone was created for each individual. The sutures were inspected for synostosis, and the degree of synostosis was assessed. Increased digital markings were recorded for both groups. Craniofacial morphology was assessed quantitatively using bony landmarks and recording of the midsagittal surface...

  4. Image sharpening by morphological filtering

    NARCIS (Netherlands)

    Schavemaker, J.G.M.; Reinders, M.J.T.; Gerbrands, J.J.; Backer, E.

    2001-01-01

    This paper introduces a class of iterative morphological image operators with applications to sharpen digitized gray-scale images. It is proved that all image operators using a concave structuring function have sharpening properties. By using a Laplacian property, we introduce the underlying partial

  5. Transparent tooth model: A study of root canal morphology using different reagents

    Directory of Open Access Journals (Sweden)

    Bhavana Gupta

    2014-01-01

    Full Text Available Background: The complexity of root canal morphology has fascinated the imaginations of many. Several techniques have been tried in the past to view the three-dimensional anatomy of the pulp canal system with varied success. It has been hypothesized in the present study that a combination of decalcifying agent and clearing agent can be used to prepare transparent tooth model. Aims: The aim of the present study was to access the efficacy of two decalcifying agent (formic acid and nitric acid and two clearing agents (methyl salicylate and eugenol to prepare transparent tooth model. Materials and Methods: The study material included 80 freshly extracted teeth both maxillary and mandibular. After decalcifying and clearing of the specimen, they were graded for transparency and haziness criteria. Results: The results of the present study indicated that methyl salicylate when used as a clearing agent showed better transparency, lower level of haziness and good root canal morphology. On the other hand samples cleared by eugenol showed good root canal morphology but lesser transparency and higher degree of haziness and yellowing of samples, more so when used in combination with nitric acid. Conclusion: It was concluded by the present study that combination of nitric acid when used with methyl salicylate proved to be the best combination for the preparation of the transparent tooth model.

  6. [Progression of tumors: etiologic, morphologic and molecular-biological aspects].

    Science.gov (United States)

    Turosov, V S

    1992-01-01

    Two aspects can be distinguished in multistage carcinogenesis: etiological one (every stage is induced by a specific for this stage agent) and morphobiological aspect (every stage is characterized by specific morphological, genetic and other properties). The schema of the multistage carcinogenesis is presented in which morphological stages (diffuse and focal hyperplasia, benign tumours, dysplasia, carcinoma in situ, various phases of malignant tumour progression) are placed against genetic alterations. L. Foulds concept of tumour progression is discussed with special emphasis on precancerous stages, possibilities of cancer development de novo, and independent progression of different tumour characters. The following types of carcinogenesis are listed on the basis of interrelationship between etiological and genetic factors: 1) carcinogenesis induced by genotoxic agents; a) one agent is acting at high dose and for a long time thus ensuring the activation of protooncogenes and all stages of tumour progression (initiation, promotion, various phases of malignant tumour); b) those acting during a very short time, however sufficient for developing the genetic program working automatically without further exposure to known carcinogens (irradiation in case of the atomic bomb explosion or effect of short-living alkylating agents): in this case there is no stage of promotion; 2) carcinogenesis by non-genotoxic carcinogens (their mode of action is still unclear, the only human example is carcinogenesis by hormones); 3) development of tumours in frane of the two (or three) stage carcinogenesis when every stage is provoked by its own etiological factor, no human examples are known as yet; 4) development of tumours due to the genetic mechanism making the organism highly susceptible to the minimal doses of carcinogens as is the case with skin cancer by ultraviolet light in patients with xeroderma pigmentosum, the genetic damage in itself has nothing to do with tumour formation; 5

  7. PENETRATION ENHANCEMENT OF MEDICINAL AGENTS

    OpenAIRE

    Sharma Ganesh N.; Sanadya Jyotsana; Kaushik Avinash; Dwivedi Abha

    2012-01-01

    Many current therapeutic agents like antibiotics, ionizable and peptide drugs are impermeable or do not possess the requisite physicochemical properties for efficient transport through outer tissue barrier to attain therapeutic blood level. For this reason the delivery of such drugs through barriers is currently one of the major interests in pharmaceutical research. Penetration enhancers or promoters are agents that have no therapeutic properties of their own but can transport the sorption of...

  8. Agents in E-learning

    OpenAIRE

    S. Mencke; Dumke, R

    2007-01-01

    This paper presents a framework to describe thecrossover domain of e-learning and agent technology.Furthermore it is used to classify existing work and possiblestarting points for the future development of agenttechniques and technologies order to enhance theperformance and the effectiveness of several aspects of elearningsystems. Agents are not a new concept but their usein the field of e-learning constitutes a basis for consequentialadvances.

  9. Handling of injectable antineoplastic agents.

    OpenAIRE

    Knowles, R S; Virden, J E

    1980-01-01

    Although the clinical toxicity of antineoplastic drugs has been well documented there is little or no information on the problems that may arise on the handling and mishandling of such agents. This paper attempts to highlight the importance of taking precautions to prevent adverse effects resulting from contact with cytotoxic drugs during handling and to suggest a practical guide for the handling of such agents.

  10. Biocontrol agents in signalling resistance

    OpenAIRE

    Loon, L C; Pieterse, C.M.J.

    2002-01-01

    The mechanisms by which biological control agents suppress disease comprise competition for nutrients, notably iron, production of antibiotics, and secretion of lytic enzymes, as well as inducing resistance in the plant. The former three mechanisms act primarily on the pathogen by decreasing its activity, growth, and/or survival and require the biocontrol agent and the pathogen to be in close proximity. Because microorganisms with biocontrol properties and soilborne pathogens are both attract...

  11. Epidemic Spreading with External Agents

    OpenAIRE

    Banerjee, Siddhartha; Gopalan, Aditya; Das, Abhik Kumar; Shakkottai, Sanjay

    2012-01-01

    We study epidemic spreading processes in large networks, when the spread is assisted by a small number of external agents: infection sources with bounded spreading power, but whose movement is unrestricted vis-\\`a-vis the underlying network topology. For networks which are `spatially constrained', we show that the spread of infection can be significantly speeded up even by a few such external agents infecting randomly. Moreover, for general networks, we derive upper-bounds on the order of the...

  12. Locating Agents in RFID Architectures

    OpenAIRE

    Abdel-Naby, Sameh; Giorgini, Paolo

    2006-01-01

    The use of software agents can create an “intelligent” interface between users’ preferences and the back‐end systems. Agents are now able to interact and communicate with each other, forming a virtual community and feeding back the user with suggestions. Innovative systems related to Asset Tracking, Inventory and Shelving architectures are more often involving advanced communication techniques (e.g., RFID); these systems are responsible for user authentication and objects verification. RFID s...

  13. Towards Building Computational Agent Schemes

    Czech Academy of Sciences Publication Activity Database

    Beuster, Gerd; Krušina, Pavel; Neruda, Roman; Rydvan, Pavel

    Wien : SpringerVerlag, 2003 - (Pearson, D.; Steele, N.; Albrecht, R.), s. 210-215 ISBN 3-211-00743-1. [ICANNGA'2003 /6./. Roanne (FR), 23.04.2003-25.04.2003] R&D Projects: GA ČR GA201/02/0428 Institutional research plan: AV0Z1030915 Keywords : multi agent system s * intelligent agent s * hybrid models Subject RIV: BA - General Mathematics

  14. Cooperation of Computational Intelligence Agents

    Czech Academy of Sciences Publication Activity Database

    Neruda, Roman

    Los Alamitos : IEEE Computer Society, 2006 - (Smari, W.; McQuay, W.), s. 256-263 ISBN 0-9785699-0-3. [International Symposium on Collaborative Technologies and System s. Las Vegas (US), 14.05.2006-17.05.2006] R&D Projects: GA AV ČR(CZ) 1ET100300419 Institutional research plan: CEZ:AV0Z10300504 Keywords : multi - agent system s * cooperative agent s * computational intelligence * ontologies Subject RIV: IN - Informatics, Computer Science

  15. Bacteriocins as potential anticancer agents

    OpenAIRE

    Sukhraj eKaur; Sumanpreet eKaur

    2015-01-01

    Cancer remains one of the leading causes of deaths worldwide, despite advances in its treatment and detection. The conventional chemotherapeutic agents used for the treatment of cancer have nonspecific toxicity towards normal body cells that cause various side effects. Secondly, cancer cells are known to develop chemotherapy resistance in due course of treatment. Thus, the demand for novel anti-cancer agents is increasing day by day. Some of the experimental studies have reported the therapeu...

  16. Bacteriocins as Potential Anticancer Agents

    OpenAIRE

    Kaur, Sumanpreet; Kaur, Sukhraj

    2015-01-01

    Cancer remains one of the leading causes of deaths worldwide, despite advances in its treatment and detection. The conventional chemotherapeutic agents used for the treatment of cancer have non-specific toxicity toward normal body cells that cause various side effects. Secondly, cancer cells are known to develop chemotherapy resistance in due course of treatment. Thus, the demand for novel anti-cancer agents is increasing day by day. Some of the experimental studies have reported the therapeu...

  17. Business Intelligence using Software Agents

    OpenAIRE

    Ana-Ramona BOLOGA; Razvan BOLOGA

    2011-01-01

    This paper presents some ideas about business intelligence today and the importance of developing real time business solutions. The authors make an exploration of links between business intelligence and artificial intelligence and focuses specifically on the implementation of software agents-based systems in business intelligence. There are briefly presented some of the few solutions proposed so far that use software agents properties for the benefit of business intelligence. The authors then...

  18. What makes virtual agents believable?

    Science.gov (United States)

    Bogdanovych, Anton; Trescak, Tomas; Simoff, Simeon

    2016-01-01

    In this paper we investigate the concept of believability and make an attempt to isolate individual characteristics (features) that contribute to making virtual characters believable. As the result of this investigation we have produced a formalisation of believability and based on this formalisation built a computational framework focused on simulation of believable virtual agents that possess the identified features. In order to test whether the identified features are, in fact, responsible for agents being perceived as more believable, we have conducted a user study. In this study we tested user reactions towards the virtual characters that were created for a simulation of aboriginal inhabitants of a particular area of Sydney, Australia in 1770 A.D. The participants of our user study were exposed to short simulated scenes, in which virtual agents performed some behaviour in two different ways (while possessing a certain aspect of believability vs. not possessing it). The results of the study indicate that virtual agents that appear resource bounded, are aware of their environment, own interaction capabilities and their state in the world, agents that can adapt to changes in the environment and exist in correct social context are those that are being perceived as more believable. Further in the paper we discuss these and other believability features and provide a quantitative analysis of the level of contribution for each such feature to the overall perceived believability of a virtual agent.

  19. 46 CFR Sec. 2 - General Agents' authority.

    Science.gov (United States)

    2010-10-01

    ... RESPONSIBILITY OF GENERAL AGENTS TO UNDERTAKE EMERGENCY REPAIRS IN FOREIGN PORTS Sec. 2 General Agents' authority. The General Agents are hereby delegated authority to undertake for the account of the...

  20. Interactions of ionic and nonionic contrast agents with thrombolytic agents

    International Nuclear Information System (INIS)

    Both the ionic and nonionic intravascular contrast media have been used before and after the administration of thrombolytic agents to evaluate clot lysis during angioplasty and the treatment of myocardial infarction. In experimental animal models, the authors found that the clot lytic efficacy of streptokinase, streptokinase-plasminogen complex, and tissue plasminogen activator (t-PA) is markedly augmented if these agents are administered within 1 hour after the angiographic producers. Furthermore, contrast agents injected after the administration of t-Pa exhibit a synergistic action. In stimulated models administration of one ionic contrast medium (Angiovist, Berlex, Wayne, NJ) and two nonionic contrast agents (Isovue-370, Squibb Diagnostics, New Brunswick, NJ; Omnipaque-350, Winthrop, NY) 15 minutes before the administration of t-PA resulted in marked enhancement of the lytic activity. Although the mechanism of this interaction is unknown at this time, it should be taken into consideration in the treatment of patients with myocardial infarction, in whom contrast agents are continually used to evaluate the therapeutic lysis. Furthermore, this interaction may be partly related to the therapeutic efficacy and/or hemorrhagic actions observed

  1. Mathematical Morphology: Star/Galaxy Differentiation & Galaxy Morphology Classification

    CERN Document Server

    Moore, J A; Drinkwater, M J; Moore, Jason A.; Pimbblet, Kevin A.; Drinkwater, Michael J.

    2006-01-01

    We present an application of Mathematical Morphology (MM) for the classification of astronomical objects, both for star/galaxy differentiation and galaxy morphology classification. We demonstrate that, for CCD images, 99.3 +/- 3.8 % of galaxies can be separated from stars using MM, with 19.4 +/- 7.9 % of the stars being misclassified. We demonstrate that, for photographic plate images, the number of galaxies correctly separated from the stars can be increased using our MM diffraction spike tool, which allows 51.0 +/- 6.0 % of the high-brightness galaxies that are inseparable in current techniques to be correctly classified, with only 1.4 +/- 0.5 % of the high-brightness stars contaminating the population. We demonstrate that elliptical (E) and late-type spiral (Sc-Sd) galaxies can be classified using MM at an accuracy of 91.4 +/- 7.8 %. It is a method involving less `free parameters' than current techniques, especially automated machine learning algorithms. The limitation of MM galaxy morphology based on seei...

  2. Geo-Agents: Design and Implement

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Geo-Agents, a multi-agent system that processes distr ib utedgeospatial information and geospatial service was presented. Firstly, the requirement for distributed geographical information process was discussed, and the architecture of Geo-Agents was introduced. Then in-depth discussions were r aised on agent system implementation, such as the basic agent, agent advertising , message passing, and collaborating. An example was also given to explain the p roblem solving process.

  3. Special issue about advances in Physical Agents

    OpenAIRE

    Cazorla Quevedo, Miguel Ángel; Matellán Olivera, Vicente

    2011-01-01

    Nowadays, there are a lot of Spanish groups which are doing research in areas related with physical agents: they use agent-based technologies concepts, especially industrial applications, robotics and domotics (physical agents) and applications related to the information society, (software agents) highlighting the similarities and synergies among physical and software agents. In this special issue we will show several works from those groups, focusing on the recent advances in Physical Agents.

  4. Learning by Observation of Agent Software Images

    OpenAIRE

    Costa, Paulo Roberto; Botelho, Luís Miguel

    2014-01-01

    Learning by observation can be of key importance whenever agents sharing similar features want to learn from each other. This paper presents an agent architecture that enables software agents to learn by direct observation of the actions executed by expert agents while they are performing a task. This is possible because the proposed architecture displays information that is essential for observation, making it possible for software agents to observe each other. The agent architecture support...

  5. Colitis associated with biological agents

    Directory of Open Access Journals (Sweden)

    Hugh James Freeman

    2012-01-01

    Full Text Available In the past, there has been considerable focus on a host of drugs and chemicals that may produce colonic toxicity. Now, a variety of new biological monoclonal antibody agents, usually administered by infusion, have appeared in the clinical realm over the last decade or so to treat different chronic inflammatory or malignant disorders.For some of these agents, adverse effects have been documented, including apparently new forms of immune-mediated inflammatory bowel disease. In some, only limited symptoms have been recorded, but in others, severe colitis with serious complications, such as bowel perforation has been recorded. In others, adverse effects may have a direct vascular or ischemic basis, while other intestinal effects may be related to a superimposed infection. Some new onset cases of ulcerative colitis or Crohn’s disease may also be attributed to the same agents used to treat these diseases, or be responsible for disease exacerbation. Dramatic and well documented side effects have been observed with ipilimumab, a humanized monoclonal antibody developed to reduce and overcome cytotoxic T-lymphocyte antigen 4, a key negative feedback regulator of the T-cell anti-tumor response. This agent has frequently been used in the treatment of different malignancies, notably, malignant melanoma. Side effects with this agent occur in up to 40% and these are believed to be largely immune-mediated. One of these is a form of enterocolitis that may be severe, and occasionally, fatal. Other agents include rituximab (an anti-CD20 monoclonal antibody, bevacizumab (a monoclonal antibody against the vascular endothelial growth factor and anti-tumor necrosis factor agents, including infliximab, adalimumab and etanercept.

  6. A multi-agent architecture for geosimulation of moving agents

    Science.gov (United States)

    Vahidnia, Mohammad H.; Alesheikh, Ali A.; Alavipanah, Seyed Kazem

    2015-10-01

    In this paper, a novel architecture is proposed in which an axiomatic derivation system in the form of first-order logic facilitates declarative explanation and spatial reasoning. Simulation of environmental perception and interaction between autonomous agents is designed with a geographic belief-desire-intention and a request-inform-query model. The architecture has a complementary quantitative component that supports collaborative planning based on the concept of equilibrium and game theory. This new architecture presents a departure from current best practices geographic agent-based modelling. Implementation tasks are discussed in some detail, as well as scenarios for fleet management and disaster management.

  7. Effect of crystals and fibrous network polymer additives on cellular morphology of microcellular foams

    Science.gov (United States)

    Miyamoto, Ryoma; Utano, Tatsumi; Yasuhara, Shunya; Ishihara, Shota; Ohshima, Masahiro

    2015-05-01

    In this study, the core-back foam injection molding was used for preparing microcelluar polypropylene (PP) foam with either a 1,3:2,4 bis-O-(4-methylbenzylidene)-D-sorbitol gelling agent (Gel-all MD) or a fibros network polymer additive (Metablen 3000). Both agent and addiive could effectively control the celluar morphology in foams but somehow different ways. In course of cooling the polymer with Gel-all MD in the mold caity, the agent enhanced the crystal nucleation and resulted in the large number of small crystals. The crystals acted as effective bubble nucleation agent in foaming process. Thus, the agent reduced the cell size and increased the cell density, drastically. Furthermore, the small crystals provided an inhomogenuity to the expanding cell wall and produced the high open cell content with nano-scale fibril structure. Gell-all as well as Metablene 3000 formed a gel-like fibrous network in melt. The network increased the elongational viscosity and tended to prevent the cell wall from breaking up. The foaming temperature window was widened by the presence of the network. Especially, the temperature window where the macro-fibrous structure was formed was expanded to the higher temperature. The effects of crystal nucleating agent and PTFE on crystals' size and number, viscoelsticity, rheological propreties of PP and cellular morphology were compared and thorougly investigated.

  8. Quantitative Morphology of Epithelial Folds.

    Science.gov (United States)

    Štorgel, Nick; Krajnc, Matej; Mrak, Polona; Štrus, Jasna; Ziherl, Primož

    2016-01-01

    The shape of spatially modulated epithelial morphologies such as villi and crypts is usually associated with the epithelium-stroma area mismatch leading to buckling. We propose an alternative mechanical model based on intraepithelial stresses generated by differential tensions of apical, lateral, and basal sides of cells as well as on the elasticity of the basement membrane. We use it to theoretically study longitudinal folds in simple epithelia and we identify four types of corrugated morphologies: compact, invaginated, evaginated, and wavy. The obtained tissue contours and thickness profiles are compared to epithelial folds observed in invertebrates and vertebrates, and for most samples, the agreement is within the estimated experimental error. Our model establishes the groove-crest modulation of tissue thickness as a morphometric parameter that can, together with the curvature profile, be used to estimate the relative differential apicobasal tension in the epithelium. PMID:26745429

  9. Morphology of polycrystalline cassiterite films

    Science.gov (United States)

    Tomaev, V. V.; Glazov, A. I.

    2014-09-01

    Polycrystalline cassiterite films have been grown by the hydropyrolytic method from a 10(H2O) + 5(SnCl2 · 2H2O) solution (in weight fractions) on corundum substrates. The crystallization regularities are considered and a comparative analysis of the properties of natural and artificial cassiterite crystals is performed. The surface morphology is investigated and the size of crystalline grains is determined by scanning electron microscopy. X-ray microprobe analysis showed that all films contain tin and oxygen atoms in a ratio corresponding (within the experimental error) to the chemical formula of tin dioxide. It is established that the surface morphology of cassiterite films is characterized by both single crystallites and aggregates of two or more crystals typical of twins. It is suggest that doping can efficiently be used to control the concentration of twins and the stability of their formation.

  10. Morphological Transformation from Galaxy Harassment

    CERN Document Server

    Moore, B; Katz, N; Moore, Ben; Lake, George; Katz, Neal

    1997-01-01

    The morphological content of galaxy clusters has undergone a remarkable transition over the past several billion years. Distant clusters at z \\sim 0.4 are filled with small spiral galaxies, many of which are disturbed and show evidence of multiple bursts of star-formation. This population is absent from nearby clusters where spheroidals comprise the faint end of the luminosity function. We present numerical simulations that follow the evolution of disk galaxies in a rich cluster owing to encounters with brighter galaxies and the cluster's tidal field-galaxy harassment. After a bursting transient phase, they undergo a complete morphological transformation from ``disks" to``spheroidals". We examine the remnants and find support for our theory in detailed comparisons of the photometry and kinematics of the spheroidal galaxies in clusters. Our model naturally accounts for the intermediate age stellar population seen in these spheroidals as well as the trend in dwarf to giant ratio with cluster richness. The final...

  11. Computational Analyses of Arabic Morphology

    CERN Document Server

    Kiraz, G A

    1994-01-01

    This paper demonstrates how a (multi-tape) two-level formalism can be used to write two-level grammars for Arabic non-linear morphology using a high level, but computationally tractable, notation. Three illustrative grammars are provided based on CV-, moraic- and affixational analyses. These are complemented by a proposal for handling the hitherto computationally untreated problem of the broken plural. It will be shown that the best grammars for describing Arabic non-linear morphology are moraic in the case of templatic stems, and affixational in the case of a-templatic stems. The paper will demonstrate how the broken plural can be derived under two-level theory via the `implicit' derivation of the singular.

  12. Morphological Disambiguation by Voting Constraints

    CERN Document Server

    Oflazer, K; Oflazer, Kemal; Tur, Gokhan

    1997-01-01

    We present a constraint-based morphological disambiguation system in which individual constraints vote on matching morphological parses, and disambiguation of all the tokens in a sentence is performed at the end by selecting parses that receive the highest votes. This constraint application paradigm makes the outcome of the disambiguation independent of the rule sequence, and hence relieves the rule developer from worrying about potentially conflicting rule sequencing. Our results for disambiguating Turkish indicate that using about 500 constraint rules and some additional simple statistics, we can attain a recall of 95-96% and a precision of 94-95% with about 1.01 parses per token. Our system is implemented in Prolog and we are currently investigating an efficient implementation based on finite state transducers.

  13. Liver morphology in morbid obesity

    DEFF Research Database (Denmark)

    Andersen, T; Gluud, C

    1984-01-01

    Literature on liver morphology in untreated obesity reveals varying prevalences of various pathological findings. The purpose of this literature study was to summarize and evaluate the published observations and to discuss discrepant findings. A complete search was aimed at utilizing bibliographi...... of obesity, age, sex, alcohol consumption, diabetes mellitus) does not point towards a single causal factor. Co-influence of additional pathogenetic factors are likely in the development of liver changes in morbid obesity....... methods including a computerized survey. Forty-one original articles were included, comprising information on liver morphology in 1515 morbidly obese patients. Liver biopsy was considered normal in 12 per cent of the cases. The most frequent abnormality reported was fatty change, present in 80 per cent of...

  14. Morphological classification of nanoceramic aggregates

    Science.gov (United States)

    Crosta, Giovanni F.; Kang, Bongwoo; Ospina, Carolina; Sung, Changmo

    2005-01-01

    Aluminum silicate nanoaggregates grown at near-room temperature on an organic template under a variety of experimental conditions have been imaged by transmission electron microscopy. Images have been automatically classified by an algorithm based on "spectrum enhancement", multivariate statistics and supervised optimization. Spectrum enhancement consists of subtracting, in the log scale, a known function of wavenumber from the angle averaged power spectral density of the image. Enhanced spectra of each image, after polynomial interpolation, have been regarded as morphological descriptors and as such submitted to principal components analysis nested with a multiobjective parameter optimization algorithm. The latter has maximized pairwise discrimination between classes of materials. The role of the organic template and of a reaction parameter on aggregate morphology has been assessed at two magnification scales. Classification results have also been related to crystal structure data derived from selected area electron diffraction patterns.

  15. Inflectional morphology analyser for Sanskrit

    OpenAIRE

    Jha, Girish Nath; Agrawal, Muktanand; Mishra, Sudhir,; Mani, Diwakar; Mishra, Diwakar; Bhadra, Manji; Singh, Surjit; Subash, -

    2007-01-01

    The paper describes a Sanskrit morphological analyzer that identifies and analyzes inflected nounforms and verb-forms in any given sandhi-free text. The system which has been developed as java servlet RDBMS can be tested at http://sanskrit.jnu.ac.in (Language Processing Tools > Sanskrit Tinanta Analyzer/Subanta Analyzer) with Sanskrit data as unicode text. Subsequently, the separate systems of subanta and ti_anta will be combined into a single system of sentence analysis with karaka interpret...

  16. Functional morphology of cephalopod gills

    OpenAIRE

    Eno, Nancy Clare

    1987-01-01

    There is a wealth of literature dealing with fish gills (Review, see Hoar & Randall, 1984), yet hardly anything is known about the gills of cephalopods. This is rather surprising considering the commercial importance of the cephalopods. In view of the paucity of information available it was necessary to start by establishing the morphology of the gills. This is covered in the first section of this thesis. Of all the cephalopods, Octopus vulgaris was singled out for mo...

  17. Morphological characteristics of psychedelic art

    OpenAIRE

    Tratnik, Luka

    2013-01-01

    The diploma paper discusses the morphological characteristics of the psychedelic art, namely the analysis of the visual characteristics of patterns and color formations, changes which psychedelics cause in the visual perception and consequently also in creativity. The topic is discussed from two perspectives: theoretical and pedagogical. Firstly, the diploma paper defines psychedelics and its influence on the creative process. Secondly, as we are discussing very potent and potentially dangero...

  18. Foot Anthropometry and Morphology Phenomena

    OpenAIRE

    Agić, Ante; NIKOLIĆ, VASILIJE; Mijović, Budimir

    2006-01-01

    Foot structure description is important for many reasons. The foot anthropometric morphology phenomena are analyzed together with hidden biomechanical functionality in order to fully characterize foot structure and function. For younger Croatian population the scatter data of the individual foot variables were interpolated by multivariate statistics. Foot structure descriptors are influenced by many factors, as a style of life, race, climate, and things of the great importance in ...

  19. Astragalar Morphology of Selected Giraffidae.

    Science.gov (United States)

    Solounias, Nikos; Danowitz, Melinda

    2016-01-01

    The artiodactyl astragalus has been modified to exhibit two trochleae, creating a double pullied structure allowing for significant dorso-plantar motion, and limited mediolateral motion. The astragalus structure is partly influenced by environmental substrates, and correspondingly, morphometric studies can yield paleohabitat information. The present study establishes terminology and describes detailed morphological features on giraffid astragali. Each giraffid astragalus exhibits a unique combination of anatomical characteristics. The giraffid astragalar morphologies reinforce previously established phylogenetic relationships. We find that the enlargement of the navicular head is a feature shared by all giraffids, and that the primitive giraffids possess exceptionally tall astragalar heads in relation to the total astragalar height. The sivatheres and the okapi share a reduced notch on the lateral edge of the astragalus. We find that Samotherium is more primitive in astragalar morphologies than Palaeotragus, which is reinforced by tooth characteristics and ossicone position. Diagnostic anatomical characters on the astragalus allow for giraffid species identifications and a better understanding of Giraffidae. PMID:27028515

  20. Influence of Selective Biochemical and Morphological Agents on Natural History of Aneurysm of Abdominal Aorta Development

    OpenAIRE

    Wołoszko, Tomasz; Skórski, Maciej; Kwasiborski, Przemysław; Kmin, Ewelina; Gałązka, Zbigniew; Pogorzelski, Ryszard

    2016-01-01

    Background The development of abdominal aortic aneurysm (AAA) is probably influenced by many factors. The role of some of these factors, such as intraluminal thrombus (ILT) or cystatin C serum levels, remains controversial. Proving their influence could have therapeutic implications for some patients with AAA. Associations between the rate of increase in diameter of an aneurysm and ILT, as well as other factors, including biochemical factors (C-Reactive Protein – CRP, cystatin C), age, sex, a...

  1. Sensors for detecting biological agents

    Directory of Open Access Journals (Sweden)

    Kim E. Sapsford

    2008-03-01

    Full Text Available Biological agents including viruses, bacteria, and other naturally occurring pathogenic organisms, along with the toxins they produce, are considered far harder to detect and defend against than chemical agents. Here we provide an overview of the predominant molecular sensing technologies for the detection of these agents. This includes biosensing strategies based upon use of antibodies, genomic analysis, biochemical testing, other recognition interactions, and cellular-based responses. We survey some popular sensing approaches, illustrate them with current examples showing how they have been applied, and discuss their intrinsic benefits and potential liabilities. Lastly, within the context of security applications, some approaches for integrating sensing technologies into field-portable devices are discussed.

  2. Agent review phase one report.

    Energy Technology Data Exchange (ETDEWEB)

    Zubelewicz, Alex Tadeusz; Davis, Christopher Edward; Bauer, Travis LaDell

    2009-12-01

    This report summarizes the findings for phase one of the agent review and discusses the review methods and results. The phase one review identified a short list of agent systems that would prove most useful in the service architecture of an information management, analysis, and retrieval system. Reviewers evaluated open-source and commercial multi-agent systems and scored them based upon viability, uniqueness, ease of development, ease of deployment, and ease of integration with other products. Based on these criteria, reviewers identified the ten most appropriate systems. The report also mentions several systems that reviewers deemed noteworthy for the ideas they implement, even if those systems are not the best choices for information management purposes.

  3. Dopamine agents for hepatic encephalopathy

    DEFF Research Database (Denmark)

    Junker, Anders Ellekær; Als-Nielsen, Bodil; Gluud, Christian;

    2014-01-01

    BACKGROUND: Patients with hepatic encephalopathy may present with extrapyramidal symptoms and changes in basal ganglia. These changes are similar to those seen in patients with Parkinson's disease. Dopamine agents (such as bromocriptine and levodopa, used for patients with Parkinson's disease) have...... therefore been assessed as a potential treatment for patients with hepatic encephalopathy. OBJECTIVES: To evaluate the beneficial and harmful effects of dopamine agents versus placebo or no intervention for patients with hepatic encephalopathy. SEARCH METHODS: Trials were identified through the Cochrane...... the trials followed participants after the end of treatment. Only one trial reported adequate bias control; the remaining four trials were considered to have high risk of bias. Random-effects model meta-analyses showed that dopamine agents had no beneficial or detrimental effect on hepatic...

  4. Multi-Agent Software Engineering

    International Nuclear Information System (INIS)

    This paper proposed an alarm-monitoring system for people based on multi-agent using maps. The system monitors the users physical context using their mobile phone. The agents on the mobile phones are responsible for collecting, processing and sending data to the server. They can determine the parameters of their environment by sensors. The data are processed and sent to the server. On the other side, a set of agents on server can store this data and check the preconditions of the restrictions associated with the user, in order to trigger the appropriate alarms. These alarms are sent not only to the user who is alarmed to avoid the appeared restriction, but also to his supervisor. The proposed system is a general purpose alarm system that can be used in different critical application areas. It has been applied for monitoring the workers of radiation sites. However, these workers can do their activity tasks in the radiation environments safely

  5. Monitoring presence of chemical agents

    International Nuclear Information System (INIS)

    The specification describes a case for use with a hand-portable chemical agent detector for continuously monitoring an atmosphere for the presence of predetermined chemical agents. The detector having means for ionizing air samples and providing at an output terminal electrical signals representative of the mobility spectrum of ionized chemical vapours produced by the ionizing means. The case comprises means for defining a chamber in the case for supporting and removably enclosing the detector, means for communicating ambient atmosphere to the chamber, electrical circuit means in the case, the circuit means being adapted to be detachably connected to the detector output terminal when the detector is positioned in the chamber and being responsive to the electrical signals for producing an alarm signal when the signals detect a chemical agent concentration in the atmosphere exceeding a predetermined concentration level, and alarm means responsive to the alarm signal. (author)

  6. Hydrodynamics, Fungal Physiology, and Morphology.

    Science.gov (United States)

    Serrano-Carreón, L; Galindo, E; Rocha-Valadéz, J A; Holguín-Salas, A; Corkidi, G

    2015-01-01

    Filamentous cultures, such as fungi and actinomycetes, contribute substantially to the pharmaceutical industry and to enzyme production, with an annual market of about 6 billion dollars. In mechanically stirred reactors, most frequently used in fermentation industry, microbial growth and metabolite productivity depend on complex interactions between hydrodynamics, oxygen transfer, and mycelial morphology. The dissipation of energy through mechanically stirring devices, either flasks or tanks, impacts both microbial growth through shearing forces on the cells and the transfer of mass and energy, improving the contact between phases (i.e., air bubbles and microorganisms) but also causing damage to the cells at high energy dissipation rates. Mechanical-induced signaling in the cells triggers the molecular responses to shear stress; however, the complete mechanism is not known. Volumetric power input and, more importantly, the energy dissipation/circulation function are the main parameters determining mycelial size, a phenomenon that can be explained by the interaction of mycelial aggregates and Kolmogorov eddies. The use of microparticles in fungal cultures is also a strategy to increase process productivity and reproducibility by controlling fungal morphology. In order to rigorously study the effects of hydrodynamics on the physiology of fungal microorganisms, it is necessary to rule out the possible associated effects of dissolved oxygen, something which has been reported scarcely. At the other hand, the processes of phase dispersion (including the suspended solid that is the filamentous biomass) are crucial in order to get an integral knowledge about biological and physicochemical interactions within the bioreactor. Digital image analysis is a powerful tool for getting relevant information in order to establish the mechanisms of mass transfer as well as to evaluate the viability of the mycelia. This review focuses on (a) the main characteristics of the two most

  7. Erythropoietic agents and the elderly.

    Science.gov (United States)

    Agarwal, Neeraj; Prchal, Josef T

    2008-10-01

    Erythropoietin (Epo) is a peptide hormone that stimulates erythropoiesis. There are several agents in clinical use and in development that either act as ligands for the cell surface receptors of Epo or promote Epo production, which stimulates erythropoiesis. These are known as erythropoietic agents. The agents already in use include epoetin alfa, epoetin beta, and darbepoetin alfa. Newer agents under active investigation include continuous erythropoietin receptor activator (CERA) or proline hydroxylase inhibitors that increase hypoxia-inducible factor-1 (HIF-1), thereby stimulating Epo production and iron availability and supply. Erythropoietic agents have been shown to promote neuronal regeneration and to decrease post-stroke infarct size in mouse models. They have also been reported to shorten survival when used to treat anemia in many cancer patients and to increase thromboembolism. In contrast, rapid decrease of Epo levels as observed in astronauts and high-altitude dwellers upon rapid descent to sea level leads to the decrease of erythroid mass, a phenomenon known as "neocytolysis." The relative decrease in the serum Epo level is known to occur in some subjects with otherwise unexplained anemia of aging. Anemia by itself is a predictor of poor physical function in the elderly and is a significant economic burden on society. One out of every five persons in the United States will be elderly by 2050. Erythropoietic agents, by preventing and treating otherwise unexplained anemias of the elderly and anemia associated with other disease conditions of the elderly, have the potential to improve the functional capacity and to decrease the morbidity and mortality in the elderly, thereby alleviating the overall burden of medical care in society. PMID:18809098

  8. Autonomous sensor manager agents (ASMA)

    Science.gov (United States)

    Osadciw, Lisa A.

    2004-04-01

    Autonomous sensor manager agents are presented as an algorithm to perform sensor management within a multisensor fusion network. The design of the hybrid ant system/particle swarm agents is described in detail with some insight into their performance. Although the algorithm is designed for the general sensor management problem, a simulation example involving 2 radar systems is presented. Algorithmic parameters are determined by the size of the region covered by the sensor network, the number of sensors, and the number of parameters to be selected. With straight forward modifications, this algorithm can be adapted for most sensor management problems.

  9. An overview of inotropic agents.

    Science.gov (United States)

    Vroom, Margreeth B

    2006-09-01

    The use of inotropic agents has been surrounded by many controversies. Recent guidelines for the treatment of patients with chronic and acute heart failure have elucidated some of the issues, but many remain. As a result, a substantial variability in the use of agents between institutions and caregivers remains, which mainly results from the lack of uniform data in the literature. Prospective randomized trials with a long-term follow-up and sufficient power are clearly needed, and a number of trials are currently in progress. PMID:16959760

  10. Rheological/Morphological Study of PS/CNT Nanocomposite Electrospun Fibers

    Science.gov (United States)

    Mazinani, Saeedeh; Ajji, Abdellah; Dubois, Charles

    2008-07-01

    This work depicts rheological characteristics of Polystyrene (PS)/Carbon Nanotube (CNT) nanocomposite solutions and their incidence on the morphological properties of final electrospun fibers. Nanocomposite fibers were obtained through electrospinning of PS/Di-Methyl Formamide (DMF) solutions containing different concentrations and types of Carbon Nanotubes. The morphology of fibers at different concentrations and types of CNTs was studied using Scanning Electron Microscopy (SEM) and Optical Microscopy. Correlation between initial CNT dispersion and final fibers morphologies was obtained using viscometry results and optical microscopy of initial solutions. The results obtained show that beads presence in fibers are due to nanoparticles agglomerations. A styrenic copolymer (Styrene-Butadiene-Styrene, SBS-Kraton) was employed as a compatibilizing agent to improve CNTs dispersion instead of chemical modification. Addition of copolymer affects both final fiber morphologies and CNT dispersion condition.

  11. Sperm Shape (Morphology): Does It Affect Fertility?

    Science.gov (United States)

    ... of the American Society for Reproductive Medicine Sperm morphology (shape): Does it affect fertility? How is a ... motility of the sperm (percentage of moving sperm), morphology of the sperm (percentage of normally shaped sperm), ...

  12. Thermally induced morphological transition of silver fractals

    DEFF Research Database (Denmark)

    Solov'yov, Ilia; Solov'yov, Andrey; Kébaili, Nouari;

    2014-01-01

    We present both experimental and theoretical study of thermally induced morphological transition of silver nanofractals. Experimentally, those nanofractals formed from deposition and diffusion of preformed silver clusters on cleaved graphite surfaces exhibit dendritic morphologies that are highly...

  13. Building Multi-Agent Systems Using Jason

    DEFF Research Database (Denmark)

    Boss, Niklas Skamriis; Jensen, Andreas Schmidt; Villadsen, Jørgen

    2010-01-01

    Technical University of Denmark (DTU). A part of this course was a short introduction to the multi-agent framework Jason, which is an interpreter for AgentSpeak, an agent-oriented programming language. As the final project in this course a solution to the Multi-Agent Programming Contest from 2007, the Gold...

  14. Self-generated morphology in lagoon reefs

    OpenAIRE

    David Blakeway; Michael G. Hamblin

    2015-01-01

    The three-dimensional form of a coral reef develops through interactions and feedbacks between its constituent organisms and their environment. Reef morphology therefore contains a potential wealth of ecological information, accessible if the relationships between morphology and ecology can be decoded. Traditionally, reef morphology has been attributed to external controls such as substrate topography or hydrodynamic influences. Little is known about inherent reef morphology in the absence of...

  15. Prominence in morphology: The notion of head

    OpenAIRE

    Fábregas, Antonio; Masini, Francesca

    2015-01-01

    In this paper we will discuss the notion of prominence in morphology by reviewing how morphological heads are defined through their prominence at different levels. After outlining the main issues and, specially, the problems posed by heads in morphology, we consider how prominence and headedness are dealt with in two different influential contemporary theories: Minimalism and Construction Morphology. Despite being very different in many respects, the two models agree that there is no need for...

  16. Automatic quantitative morphological analysis of interacting galaxies

    OpenAIRE

    Shamir, Lior; Holincheck, Anthony; Wallin, John

    2013-01-01

    The large number of galaxies imaged by digital sky surveys reinforces the need for computational methods for analyzing galaxy morphology. While the morphology of most galaxies can be associated with a stage on the Hubble sequence, morphology of galaxy mergers is far more complex due to the combination of two or more galaxies with different morphologies and the interaction between them. Here we propose a computational method based on unsupervised machine learning that can quantitatively analyz...

  17. Metal oxide nanostructures with hierarchical morphology

    Science.gov (United States)

    Ren, Zhifeng; Lao, Jing Yu; Banerjee, Debasish

    2007-11-13

    The present invention relates generally to metal oxide materials with varied symmetrical nanostructure morphologies. In particular, the present invention provides metal oxide materials comprising one or more metallic oxides with three-dimensionally ordered nanostructural morphologies, including hierarchical morphologies. The present invention also provides methods for producing such metal oxide materials.

  18. Using Agent to Coordinate Web Services

    CERN Document Server

    Liu, C H; Chen, Jason J Y

    2009-01-01

    Traditionally, agent and web service are two separate research areas. We figure that, through agent communication, agent is suitable to coordinate web services. However, there exist agent communication problems due to the lack of uniform, cross-platform vocabulary. Fortunately, ontology defines a vocabulary. We thus propose a new agent communication layer and present the web ontology language (OWL)-based operational ontologies that provides a declarative description. It can be accessed by various engines to facilitate agent communication. Further, in our operational ontologies, we define the mental attitudes of agents that can be shared among other agents. Our architecture enhanced the 3APL agent platform, and it is implemented as an agent communication framework. Finally, we extended the framework to be compatible with the web ontology language for service (OWL-S), and then develop a movie recommendation system with four OWL-S semantic web services on the framework. The benefits of this work are: 1) dynamic ...

  19. Tc-99m imaging agents

    International Nuclear Information System (INIS)

    A wide range of pharmaceuticals for labeling with Tc-99m, developed by the Soreq Radiopharmaceuticals Department, is described. Details of the production and quality control of 13 kits are given, as well as the range of results required for consistently high quality imaging agents

  20. Antibacterial activities of antineoplastic agents.

    OpenAIRE

    Bodet, C A; Jorgensen, J H; Drutz, D J

    1985-01-01

    Fourteen antineoplastic agents were examined for in vitro antibacterial activity against 101 aerobic and anaerobic bacterial isolates representing indigenous human microflora and selected opportunistic pathogens. Only 5-fluorouracil, mitomycin, and etoposide demonstrated inhibitory effects at achievable plasma concentrations, while the remaining drugs lacked appreciable antibacterial activities.

  1. Raspberry Pi for secret agents

    CERN Document Server

    Sjogelid, Stefan

    2015-01-01

    This book is an easy-to-follow guide with practical examples in each chapter. Suitable for the novice and expert alike, each topic provides a fast and easy way to get started with exciting applications and also guides you through setting up the Raspberry Pi as a secret agent toolbox.

  2. Identity Management in Agent Systems

    NARCIS (Netherlands)

    Brazier, F.M.T.; Groot, de D.R.A.

    2006-01-01

    If agent-based applications are to be used in large scale, open environments, security is a main issue; digital identity management (DIDM) an essential element. DIDM is needed to be able to determine the rights and obligations of the four main

  3. Kriitikute lemmikfilm on "Agent Sinikael"

    Index Scriptorium Estoniae

    2003-01-01

    Eesti Filmiajakirjanike Ühing andis kümnendat korda välja auhinda Aasta film 2002. Parimaks filmiks tunnistati mängufilm "Agent Sinikael" : režissöör Marko Raat. Viimane sai preemiaks Neitsi Maali kuju ja 12 000 krooni

  4. Improving agents using reliable communication

    Science.gov (United States)

    Zheng, Jinbin

    2013-10-01

    Recent advances in introspective modalities and linear time symmetries do not necessarily obviate the need for web browsers [1]. In our research, we disprove the exploration of agents, which embodies the appropriate principles of electrical engineering. Here we demonstrate that even though semaphores and XML [1] are mostly incompatible, randomized algorithms and write-back caches are mostly incompatible.

  5. Foodborne illness and microbial agents

    Science.gov (United States)

    Foodborne illnesses result from the consumption of food containing microbial agents such as bacteria, viruses, parasites or food contaminated by poisonous chemicals or bio-toxins. Pathogen proliferation is due to nutrient composition of foods, which are capable of supporting the growth of microorgan...

  6. Bridging humans via agent networks

    International Nuclear Information System (INIS)

    Recent drastic advance in telecommunication networks enabled the human organization of new class, teleorganization, which differ from any existing organization in that the organization which is easy to create by using telecommunication networks is virtual and remote, that people can join multiple organizations simultaneously, and that the organization can involve people who may not know each other. In order to enjoy the recent advance in telecommunication, the agent networks to help people organize themselves are needed. In this paper, an architecture of agent networks, in which each agent learns the preference or the utility functioin of the owner, and acts on behalf of the owner in maintaining the organization, is proposed. When an agent networks supports a human organization, the conventional human interface is divided into personal and social interfaces. The functionalities of the social interface in teleconferencing and telelearning were investigated. In both cases, the existence of B-ISDN is assumed, and the extension to the business meeting scheduling using personal handy phone (PHS) networks with personal digital assistant (PDA) terminals is expected. These circumstances are described. Mutual selection protocols (MSP) and their dynamic properties are explained. (K.I.)

  7. Pelvic morphology in ischiofemoral impingement

    Energy Technology Data Exchange (ETDEWEB)

    Bredella, Miriam A.; Azevedo, Debora C.; Oliveira, Adriana L.; Simeone, Frank J.; Chang, Connie Y.; Torriani, Martin [Massachusetts General Hospital, Department of Radiology, Musculoskeletal Imaging and Intervention, Boston, MA (United States); Stubbs, Allston J. [Wake Forest University School of Medicine, Department of Orthopedic Surgery, Division of Sports Medicine, Winston-Salem, NC (United States)

    2014-11-06

    To assess MRI measures to quantify pelvic morphology that may predispose to ischiofemoral impingement (IFI). We hypothesized that patients with IFI have a wider interischial distance and an increased femoral neck angle compared with normal controls. The study was IRB-approved and complied with HIPAA guidelines. IFI was diagnosed based on clinical findings (hip or buttock pain) and ipsilateral edema of the quadratus femoris muscle on MRI. Control subjects did not report isolated hip/buttock pain and underwent MRI for surveillance of neoplasms or to exclude pelvic fractures. Two MSK radiologists measured the ischiofemoral (IF) and quadratus femoris (QF) distance, the ischial angle as a measure of inter-ischial distance, and the femoral neck angle. The quadratus femoris muscle was evaluated for edema. Groups were compared using ANOVA. Multivariate standard least-squares regression modeling was used to control for age and gender. The study group comprised 84 patients with IFI (53 ± 16 years, 73 female, 11 male) and 51 controls (52 ± 16 years, 33 female, 18 male). Thirteen out of 84 patients (15 %) had bilateral IFI. Patients with IFI had decreased IF and QF distance (p < 0.0001), increased ischial angle (p = 0.004), and increased femoral neck angle (p = 0.02) compared with controls, independent of age and gender. Patients with IFI have increased ischial and femoral neck angles compared with controls. These anatomical variations in pelvic morphology may predispose to IFI. MRI is a useful method of not only assessing the osseous and soft-tissue abnormalities associated with IFI, but also of quantifying anatomical variations in pelvic morphology that can predispose to IFI. (orig.)

  8. Pelvic morphology in ischiofemoral impingement

    International Nuclear Information System (INIS)

    To assess MRI measures to quantify pelvic morphology that may predispose to ischiofemoral impingement (IFI). We hypothesized that patients with IFI have a wider interischial distance and an increased femoral neck angle compared with normal controls. The study was IRB-approved and complied with HIPAA guidelines. IFI was diagnosed based on clinical findings (hip or buttock pain) and ipsilateral edema of the quadratus femoris muscle on MRI. Control subjects did not report isolated hip/buttock pain and underwent MRI for surveillance of neoplasms or to exclude pelvic fractures. Two MSK radiologists measured the ischiofemoral (IF) and quadratus femoris (QF) distance, the ischial angle as a measure of inter-ischial distance, and the femoral neck angle. The quadratus femoris muscle was evaluated for edema. Groups were compared using ANOVA. Multivariate standard least-squares regression modeling was used to control for age and gender. The study group comprised 84 patients with IFI (53 ± 16 years, 73 female, 11 male) and 51 controls (52 ± 16 years, 33 female, 18 male). Thirteen out of 84 patients (15 %) had bilateral IFI. Patients with IFI had decreased IF and QF distance (p < 0.0001), increased ischial angle (p = 0.004), and increased femoral neck angle (p = 0.02) compared with controls, independent of age and gender. Patients with IFI have increased ischial and femoral neck angles compared with controls. These anatomical variations in pelvic morphology may predispose to IFI. MRI is a useful method of not only assessing the osseous and soft-tissue abnormalities associated with IFI, but also of quantifying anatomical variations in pelvic morphology that can predispose to IFI. (orig.)

  9. Cartography – morphology – topology

    DEFF Research Database (Denmark)

    Dinesen, Cort Ross; Peder Pedersen, Claus

    2010-01-01

    I 2004 a Summer School was established on the Greek island of Hydra. The was to be the basis of research-based morphological and topological studies, which have since taken place for 4 weeks of every year. Starting with Hydra’s topography different ways of considering topology were developed. The...... into force-fields and modes of effect. This supple viewpoint sought to create a topology from which to extract experiences reaching beyond the topography of Hydra, and capable of bringing together numerous levels into an open work; an interaction between form and action; a form of architecture of the...

  10. Anchor Toolkit - a secure mobile agent system

    OpenAIRE

    Mudumbai, Srilekha S.; Johnston, William; Essiari, Abdelilah

    2008-01-01

    Mobile agent technology facilitates intelligent operation in software systems with less human interaction. Major challenge to deployment of mobile agents include secure transmission of agents and preventing unauthorized access to resources between interacting systems, as either hosts, or agents, or both can act maliciously. The Anchor toolkit, designed by LBNL, handles the transmission and secure management of mobile agents in a heterogeneous distributed computing environment. It provide...

  11. Providing Reliable Agents for Electronic Commerce

    OpenAIRE

    Straßer, Markus; Rothermel, Kurt; Maihöfer, Christian

    1998-01-01

    It is widely agreed that mobile agents in conjunction with WWW technology will provide the technical foundation for future electronic commerce. A prerequisite for the use of mobile agents in a commercial environment is, that agents have to be executed reliable, independent of communication and node failure. In this paper, we first present a recently proposed fault-tolerant protocol to ensure the exactly-once execution of an agent by monitoring the agents execut...

  12. Morphology of technological levels in an innovation propagation model

    Science.gov (United States)

    Kim, Yup; Han, Bumhee; Yook, Soon-Hyung

    2010-10-01

    We study the dynamical properties of the propagation of innovation on a two-dimensional lattice, random network, scale-free network, and Cayley tree. In order to investigate the diversity of technological level, we study the scaling property of width, W(N,t) , which represents the root mean square of the technological level of agents. Here, N is the total number of agents. From the numerical simulations, we find that the steady-state value of W(N,t) , Wsat(N) , scales as Wsat(N)˜N-1/2 when the system is in a flat ordered phase for d≥2 . In the flat ordered phase, most of the agents have the same technological level. On the other hand, when the system is in a smooth disordered phase, the value of Wsat(N) does not depend on N . These behaviors are completely different from those observed on a one-dimensional (1D) lattice. By considering the effect of the underlying topology on the propagation dynamics for d≥2 , we also provide a mean-field analysis for Wsat(N) , which agrees very well with the observed behaviors of Wsat(N) . This directly shows that the morphological properties in order-disorder transition on a 1D lattice is completely different from that on higher dimensions. It also provides an evidence that the upper critical dimension for the roughening transition of the propagation of innovation is du=2 .

  13. Halide test agent replacement study

    Energy Technology Data Exchange (ETDEWEB)

    Banks, E.M.; Freeman, W.P.; Kovach, B.J. [and others

    1995-02-01

    The intended phaseout of the chlorofluorocarbons (CFCs) from commercial use required the evaluation of substitute materials for the testing for leak paths through both individual adsorbers and installed adsorbent banks. The American Society of Mechanical Engineers (ASME) Committee on Nuclear Air and Gas Treatment (CONAGT) is in charge of maintaining the standards and codes specifying adsorbent leak test methods for the nuclear safety related air cleaning systems. The currently published standards and codes cite the use of R-11, R-12 and R-112 for leak path test agents. All of these compounds are CFCs. There are other agencies and organizations (USDOE, USDOD and USNRC) also specifying testing for leak paths or in some cases for special life tests using the above compounds. The CONAGT has recently developed criteria for the suitability evaluation of substitute test agents. On the basis of these criteria, several compounds were evaluated for their acceptability as adsorbent bed leak and life test agents. The ASME CONAGT Test Agent Qualification Criteria. The test agent qualification is based on the following parameters: (1) Similar retention times on activated carbons at the same concentration levels as one of the following: R-11, R-12, R-112 or R-112a. (2) Similar lower detection limit sensitivity and precision in the concentration range of use as R-11, R-12, R-112 and R-112a. (3) Gives the same in-place leak test results as R-11, R-12, R-112, or R-112a. (4) Chemical and radiological stability under the use conditions. (5) Causes no degradation of the carbon and its impregnant or of the other NATS components under the use conditions. (6) Is listed in the USEPA Toxic Substances Control Act (TSCA) inventory for commercial use.

  14. Biologic agents in juvenile spondyloarthropathies.

    Science.gov (United States)

    Katsicas, María Martha; Russo, Ricardo

    2016-01-01

    The juvenile spondyloarthropathies (JSpA) are a group of related rheumatic diseases characterized by involvement of peripheral large joints, axial joints, and entheses (enthesitis) that begin in the early years of life (prior to 16(th) birthday).The nomenclature and concept of spondyloarthropathies has changed during the last few decades. Although there is not any specific classification of JSpA, diseases under the spondyloarthropathy nomenclature umbrella in the younger patients include: the seronegative enthesitis and arthropathy (SEA) syndrome, juvenile ankylosing spondylitis, reactive arthritis, and inflammatory bowel disease-associated arthritis. Moreover, the ILAR criteria for Juvenile Idiopathic Arthritis includes two categories closely related to spondyloarthritis: Enthesitis-related arthritis and psoriatic arthritis.We review the pathophysiology and the use of biological agents in JSpA. JSpA are idiopathic inflammatory diseases driven by an altered balance in the proinflammatory cytokines. There is ample evidence on the role of tumor necrosis factor (TNF) and interleukin-17 in the physiopathology of these entities. Several non-biologic and biologic agents have been used with conflicting results in the treatment of these complex diseases. The efficacy and safety of anti-TNF agents, such as etanercept, infliximab and adalimumab, have been analysed in controlled and uncontrolled trials, usually showing satisfactory outcomes. Other biologic agents, such as abatacept, tocilizumab and rituximab, have been insufficiently studied and their role in the therapy of SpA is uncertain. Interleukin-17-blocking agents are promising alternatives for the treatment of JSpA patients in the near future. Recommendations for the treatment of patients with JSpA have recently been proposed and are discussed in the present review. PMID:26968522

  15. Migration Dynamics in Artificial Agent Societies

    Directory of Open Access Journals (Sweden)

    Harjot Kaur

    2014-02-01

    Full Text Available An Artificial Agent Society can be defined as a collection of agents interacting with each other for some purpose and/or inhabiting a specific locality, possibly in accordance to some common norms/rules. These societies are analogous to human and ecological societies, and are an expanding and emerging field in research about social systems. Social networks, electronic markets and disaster management organizations can be viewed as such artificial (open agent societies and can be best understood as computational societies. Members of such artificial agent societies are heterogeneous intelligent software agents which are operating locally and cooperating and coordinating with each other in order to achieve goals of an agent society. These artificial agent societies have some kind of dynamics existing in them in terms of dynamics of Agent Migration, Role-Assignment, Norm- Emergence, Security and Agent-Interaction. In this paper, we have described the dynamics of agent migration process, starting from the various types of agent migration, causes or reasons for agent migration, consequences of agent migration, and an agent migration framework to model the its behavior for migration of agents between societies.

  16. Laser interrogation of surface agents (LISA) for chemical agent reconnaissance

    Science.gov (United States)

    Higdon, N. S.; Chyba, Thomas H.; Richter, Dale A.; Ponsardin, Patrick L.; Armstrong, Wayne T.; Lobb, C. T.; Kelly, Brian T.; Babnick, Robert D.; Sedlacek, Arthur J., III

    2002-06-01

    Laser Interrogation of Surface Agents (LISA) is a new technique which exploits Raman scattering to provide standoff detection and identification of surface-deposited chemical agents. ITT Industries, Advanced Engineering and Sciences Division is developing the LISA technology under a cost-sharing arrangement with the US Army Soldier and Biological Chemical Command for incorporation on the Army's future reconnaissance vehicles. A field-engineered prototype LISA-Recon system is being designed to demonstrate on-the- move measurements of chemical contaminants. In this article, we will describe the LISA technique, data form proof-of- concept measurements, the LISA-Recon design, and some of the future realizations envisioned for military sensing applications.

  17. Change Detection via Morphological Comparative Filters

    Science.gov (United States)

    Vizilter, Y. V.; Rubis, A. Y.; Zheltov, S. Y.; Vygolov, O. V.

    2016-06-01

    In this paper we propose the new change detection technique based on morphological comparative filtering. This technique generalizes the morphological image analysis scheme proposed by Pytiev. A new class of comparative filters based on guided contrasting is developed. Comparative filtering based on diffusion morphology is implemented too. The change detection pipeline contains: comparative filtering on image pyramid, calculation of morphological difference map, binarization, extraction of change proposals and testing change proposals using local morphological correlation coefficient. Experimental results demonstrate the applicability of proposed approach.

  18. Morphologic alterations after transluminal angioplasty

    International Nuclear Information System (INIS)

    Despite the widespread clinical use of percutaneous transluminal angioplasty, the mechanism by which enlargement of the arterial lumen is achieved by this technique has been poorly understood. In the original description of transluminal angioplasty in 1964, the effectiveness of the procedure was attributed to compression of the atheromatous plaque against a relatively unyielding artery wall. This mechanism was subsequently endorsed in relation to angioplasty using the balloon catheter. The concept of plaque compression or displacement or of herniation of the puttylike athermatous intima into the artery wall was generally accepted by the early pioneers in transluminal angioplasty. This mechanism did not, however, correspond to clinical and morphologic observations that plaques were generally rigid and calcific rather than plastic and could not readily be compressed or deformed. Angiographic observations before and after dilatation have not always been helpful in defining the mechanism since angiography reveals only the lumen contour and does not provide sufficient information concerning the thickness of the arterial wall or the size, configuration, or precise boundaries of plaques. Although direct observation of lesions and associated artery walls immediately after balloon dilatation could provide the necessary information, such data are difficult to obtain since arteries and plaques are rarely directly inspected after dilatation in the living patient. Knowledge of the morphologic consequences of balloon dilatation in human arteries has therefore been obtained mainly from experimental studies of postmortem arteries and corresponding angiographic images and from specimens obtained from amputated limbs or after death

  19. Morphology of atherosclerotic coronary arteries

    Science.gov (United States)

    Holme, Margaret N.; Schulz, Georg; Deyhle, Hans; Hieber, Simone Elke; Weitkamp, Timm; Beckmann, Felix; Herzen, Julia; Lobrinus, Johannes A.; Montecucco, Fabrizio; Mach, François; Zumbuehl, Andreas; Saxer, Till; Müller, Bert

    2012-10-01

    Atherosclerosis, the narrowing of vessel diameter and build-up of plaques in coronary arteries, leads to an increase in the shear stresses present, which can be used as a physics-based trigger for targeted drug delivery. In order to develop appropriate nanometer-size containers, one has to know the morphology of the critical stenoses with isotropic micrometer resolution. Micro computed tomography in absorption and phase contrast mode provides the necessary spatial resolution and contrast. The present communication describes the pros and cons of the conventional and synchrotron radiation-based approaches in the visualization of diseased human and murine arteries. Using registered datasets, it also demonstrates that multi-modal imaging, including established histology, is even more powerful. The tomography data were evaluated with respect to cross-section, vessel radius and maximal constriction. The average cross-section of the diseased human artery (2.31 mm2) was almost an order of magnitude larger than the murine one (0.27 mm2), whereas the minimal radius differs only by a factor of two (0.51 mm versus 0.24 mm). The maximal constriction, however, was much larger for the human specimen (85% versus 49%). We could also show that a plastic model used for recent experiments in targeted drug delivery represents a very similar morphology, which is, for example, characterized by a maximal constriction of 82%. The tomography data build a sound basis for flow simulations, which allows for conclusions on shear stress distributions in stenosed blood vessels.

  20. Can ionic liquids be used as templating agents for controlled design of uranium-containing nanomaterials?

    International Nuclear Information System (INIS)

    Graphical abstract: - Highlights: • Uranium oxides nanoparticles prepared using ionic liquids. • IL cation alkyl length impacts oxide morphology. • Low temperature UO2 synthesis. - Abstract: Nanostructured uranium oxides have been prepared in ionic liquids as templating agents. Using the ionic liquids as reaction media for inorganic nanomaterials takes advantage of the pre-organized structure of the ionic liquids which in turn controls the morphology of the inorganic nanomaterials. Variation of ionic liquid cation structure was investigated to determine the impact on the uranium oxide morphologies. For two ionic liquid cations, increasing the alkyl chain length increases the aspect ratio of the resulting nanostructured oxides. Understanding the resulting metal oxide morphologies could enhance fuel stability and design

  1. The New Agent: A Qualitative Study to Strategically Adapt New Agent Professional Development

    Science.gov (United States)

    Baker, Lauri M.; Hadley, Gregg

    2014-01-01

    The qualitative study reported here assessed the needs of agents related to new agent professional development to improve the current model. Agents who participated in new agent professional development within the last 5 years were selected to participate in focus groups to determine concerns and continued needs. Agents enjoyed networking and…

  2. Tagging and Morphological Disambiguation of Turkish Text

    CERN Document Server

    Oflazer, K; Oflazer, Kemal; Kuruoz, Ilker

    1994-01-01

    Automatic text tagging is an important component in higher level analysis of text corpora, and its output can be used in many natural language processing applications. In languages like Turkish or Finnish, with agglutinative morphology, morphological disambiguation is a very crucial process in tagging, as the structures of many lexical forms are morphologically ambiguous. This paper describes a POS tagger for Turkish text based on a full-scale two-level specification of Turkish morphology that is based on a lexicon of about 24,000 root words. This is augmented with a multi-word and idiomatic construct recognizer, and most importantly morphological disambiguator based on local neighborhood constraints, heuristics and limited amount of statistical information. The tagger also has functionality for statistics compilation and fine tuning of the morphological analyzer, such as logging erroneous morphological parses, commonly used roots, etc. Preliminary results indicate that the tagger can tag about 98-99\\% of the...

  3. Developmental morphology of Knemidokoptes pilae on an infested red-crowned parakeet (Cyanoramphus novaezelandiae).

    Science.gov (United States)

    Kim, Kyoo-Tae; Lee, Seung-Hun; Kwak, Dongmi

    2016-04-01

    A captive 4-year-old female red-crowned parakeet (Cyanoramphus novaezelandiae) presented with anorexia, diminished activity and thick, beige, crusted lesions over the cere, legs, wings and cloaca. Deep skin scrapings from various lesions identified Knemidokoptes pilae as the causative agent. For treatment, the crusts were debrided, and the lesions were topically treated with ivermectin, chlorhexidine and silver sulfadiazine. The parakeet died the day after treatment. Previous studies examining K. pilae have focused primarily on the morphologic characteristics of adult female mites. This study presents a more comprehensive morphologic analysis, with examination of K. pilae at different stages of development (eggs, larvae and adult males and females). PMID:26596465

  4. Morphology evolution of gold nanoparticles as function of time, temperature, and Au(III)/sodium ascorbate molar ratio

    Energy Technology Data Exchange (ETDEWEB)

    Priolisi, Ornella, E-mail: ornella.priolisi@depretto.gov.it [ITIS “De Pretto” (Italy); Fabrizi, Alberto, E-mail: fabrizi@gest.unipd.it [University of Padova, Department of Management and Engineering (Italy); Deon, Giovanna, E-mail: giovanna.deon@depretto-vi.it [ITIS “De Pretto” (Italy); Bonollo, Franco, E-mail: bonollo@gest.unipd.it [University of Padova, Department of Management and Engineering (Italy); Cattini, Stefano, E-mail: stefano.cattini@unimore.it [University of Modena and Reggio Emilia, Department of Engineering Enzo Ferrari (Italy)

    2016-01-15

    In this work the morphology evolution of Au nanoparticles (AuNPs), obtained by direct reduction, was studied as a function of time, temperature, and Au(III)/sodium ascorbate molar ratio. The NPs morphology was examined by transmission electron microscope with image analysis, while time evolution was investigated by visible and near-infrared absorption spectroscopy and dynamic light scattering. It is found that initially formed star-like NPs transform in more spheroidal particles and the evolution appears more rapid by increasing the temperature while a large amount of reducing agent prevents the remodeling of AuNPs. An explication of morphology evolution is proposed.

  5. Morphology evolution of gold nanoparticles as function of time, temperature, and Au(III)/sodium ascorbate molar ratio

    International Nuclear Information System (INIS)

    In this work the morphology evolution of Au nanoparticles (AuNPs), obtained by direct reduction, was studied as a function of time, temperature, and Au(III)/sodium ascorbate molar ratio. The NPs morphology was examined by transmission electron microscope with image analysis, while time evolution was investigated by visible and near-infrared absorption spectroscopy and dynamic light scattering. It is found that initially formed star-like NPs transform in more spheroidal particles and the evolution appears more rapid by increasing the temperature while a large amount of reducing agent prevents the remodeling of AuNPs. An explication of morphology evolution is proposed.

  6. CATS-based Agents That Err

    Science.gov (United States)

    Callantine, Todd J.

    2002-01-01

    This report describes preliminary research on intelligent agents that make errors. Such agents are crucial to the development of novel agent-based techniques for assessing system safety. The agents extend an agent architecture derived from the Crew Activity Tracking System that has been used as the basis for air traffic controller agents. The report first reviews several error taxonomies. Next, it presents an overview of the air traffic controller agents, then details several mechanisms for causing the agents to err in realistic ways. The report presents a performance assessment of the error-generating agents, and identifies directions for further research. The research was supported by the System-Wide Accident Prevention element of the FAA/NASA Aviation Safety Program.

  7. Boron nitride nanotubes coated with organic hydrophilic agents: Stability and cytocompatibility studies

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Tiago Hilário; Soares, Daniel Crístian Ferreira; Moreira, Luciana Mara Costa; Ornelas da Silva, Paulo Roberto [Serviço de Nanotecnologia, Centro de Desenvolvimento da Tecnologia Nuclear CDTN/CNEN, Avenida Presidente Antônio Carlos, 6.627, Campus da UFMG, Pampulha, CEP 31270-901 Belo Horizonte, Minas Gerais (Brazil); Gouvêa dos Santos, Raquel [Laboratório de Radiobiologia, Centro de Desenvolvimento da Tecnologia Nuclear CNEN/CDTN, Av. Presidente Antônio Carlos 6.627, Campus da UFMG, Pampulha, 31270-901 Belo Horizonte, Minas Gerais (Brazil); Barros de Sousa, Edésia Martins, E-mail: sousaem@cdtn.br [Serviço de Nanotecnologia, Centro de Desenvolvimento da Tecnologia Nuclear CDTN/CNEN, Avenida Presidente Antônio Carlos, 6.627, Campus da UFMG, Pampulha, CEP 31270-901 Belo Horizonte, Minas Gerais (Brazil)

    2013-12-01

    In the present study, Boron Nitride Nanotubes (BNNTs) were synthesized and functionalized with organic hydrophilic agents constituted by glucosamine (GA), polyethylene glycol (PEG){sub 1000}, and chitosan (CH) forming new singular systems. Their size, distribution, and homogeneity were determined by photon correlation spectroscopy, while their surface charge was determined by laser Doppler anemometry. The morphology and structural organization were evaluated by Transmission Electron Microscopy. The functionalization was evaluated by Thermogravimetry analysis and Fourier Transformer Infrared Spectroscopy. The results showed that BNNTs were successfully obtained and functionalized, reaching a mean size and dispersity deemed adequate for in vitro studies. The in vitro stability tests also revealed a good adhesion of functionalized agents on BNNT surfaces. Finally, the in vitro cytocompatibility of functionalized BNNTs against MCR-5 cells was evaluated, and the results revealed that none of the different functionalization agents disturbed the propagation of normal cells up to the concentration of 50 μg/mL. Furthermore, in this concentration, no significantly chromosomal or morphologic alterations or increase in ROS (Reactive Oxygen Species) could be observed. Thus, findings from the present study reveal an important stability and cytocompatibility of functionalized BNNTs as new potential drugs or radioisotope nanocarriers to be applied in therapeutic procedures. - Highlights: • BNNTs were synthesized and functionalized with organic hydrophilic agents. • Hydrophilic molecules do not alter the biocompatibility profile of BNNTs. • No significantly chromosomal or morphologic alterations in ROS could be observed.

  8. Biological effects of mutagenic agents

    International Nuclear Information System (INIS)

    There is an increasing body of evidence that mutagenic agents (biological, chemical and physical) play an important role in the etiology of human diseases. Mutations may occur in the germinal as well as in the somatic cells. Mutations of the germ cells may result on infertility or fertilization of damaged cells, the later leading to abortion or birth of a malformed fetus. Somatic-cells mutations may have various biological effects, depending on the period of the human life at which the mutation occurs. If it occurs during the prenatal life, a teratogenic or carcinogenic effect will be observed. If the somatic cell is damaged during the postnatal life, this will lead to neoplastic transformation. Therefore it is extremely important to know the mutagenic, teratogenic and carcinogenic effects of various biological, chemical and physical agents in order to eliminate them from our environment. (author). 13 refs, 4 figs, 1 tab

  9. Extension agents and conflict narratives

    DEFF Research Database (Denmark)

    Bond, Jennifer Lauren

    2016-01-01

    Purpose: This work investigated the narratives of development extensionists in relation to natural resource conflict, in order to understand the competing discourses surrounding the wicked problems of natural resource management in Laikipia County, Kenya. Methodology: Q methodology was used to...... professionals from government, non-government, faith-based and private organizations. Findings: Four factors were elicited from the data, labelled—A: ‘Improved Leadership’; B: ‘Resource-centred conflict’; C: ‘Improved Governance’; and D: ‘Improved Management’. Practical Implications: Narratives of neo...... resource conflict. Originality: This work contributes to a growing body of literature interested in the role of extension agents in conflict management. By applying Q methodology, this work has shown that while extension agents are involved in conflict management, their perceptions of these conflicts are...

  10. Agent Based Individual Traffic Guidance

    DEFF Research Database (Denmark)

    Wanscher, Jørgen

    This thesis investigates the possibilities in applying Operations Research (OR) to autonomous vehicular traffic. The explicit difference to most other research today is that we presume that an agent is present in every vehicle - hence Agent Based Individual Traffic guidance (ABIT). The next...... that the system can be divided into two separate constituents. The immediate dispersion, which is used for small areas and quick response, and the individual alleviation, which considers the longer distance decision support. Both of these require intrinsicate models and cost functions which at the...... beginning of the project were not previously considered. We define a special inseparable cost function and develop a solution complex capable of using this cost function. In relation to calibration and estimation of statistical models used for dynamic route guidance we worked with generating random number...

  11. [Infectious agents and autoimmune diseases].

    Science.gov (United States)

    Riebeling-Navarro, C; Madrid-Marina, V; Camarena-Medellín, B E; Peralta-Zaragoza, O; Barrera, R

    1992-01-01

    In this paper the molecular aspects of the relationships between infectious agents and autoimmune diseases, the mechanisms of immune response to infectious agents, and the more recent hypotheses regarding the cause of autoimmune diseases are discussed. The antigens are processed and selected by their immunogenicity, and presented by HLA molecules to the T cell receptor. These events initiate the immune response with the activation and proliferation of T-lymphocytes. Although there are several hypotheses regarding the cause of autoimmune diseases and too many findings against and in favor of them, there is still no conclusive data. All these hypothesis and findings are discussed in the context of the more recent advances. PMID:1615352

  12. Oral agents in multiple sclerosis.

    Science.gov (United States)

    Lorefice, L; Fenu, G; Frau, J; Coghe, G C; Marrosu, M G; Cocco, E

    2015-01-01

    Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system. Disease-modifying drugs licensed for MS treatment have been developed to reduce relapse rates and halt disease progression. The majority of current MS drugs involve regular, parenteral administration, affecting long-term adherence and thus reducing treatment efficacy. Over the last two decades great progress has been made towards developing new MS therapies with different modes of action and biologic effects. In particular, oral drugs have generated much interest because of their convenience and positive impact on medication adherence. Fingolimod was the first launched oral treatment for relapsing-remitting MS; recently, Teriflunomide and Dimethyl fumarate have also been approved as oral disease-modifying agents. In this review, we summarize and discuss the history, pharmacodynamics, efficacy, and safety of oral agents that have been approved or are under development for the selective treatment of MS. PMID:25924620

  13. Logical Theories for Agent Introspection

    DEFF Research Database (Denmark)

    Bolander, Thomas

    2004-01-01

    Artificial intelligence systems (agents) generally have models of the environments they inhabit which they use for representing facts, for reasoning about these facts and for planning actions. Much intelligent behaviour seems to involve an ability to model not only one's external environment but...... self-reference. In the standard approach taken in artificial intelligence, the model that an agent has of its environment is represented as a set of beliefs. These beliefs are expressed as logical formulas within a formal, logical theory. When the logical theory is expressive enough to allow...... introspective reasoning, the presence of self-reference causes the theory to be prone to inconsistency. The challenge therefore becomes to construct logical theories supporting introspective reasoning while at the same time ensuring that consistency is retained. In the thesis, we meet this challenge by devising...

  14. Injectable agents affecting subcutaneous fats.

    Science.gov (United States)

    Chen, David Lk; Cohen, Joel L; Green, Jeremy B

    2015-09-01

    Mesotherapy is an intradermal or subcutaneous injection of therapeutic agents to induce local effects, and was pioneered in Europe during the 1950s. For the past 2 decades, there has been significant interest in the use of mesotherapy for minimally invasive local fat contouring. Based on the theorized lipolytic effects of the agent phosphatidylcholine, initial attempts involved its injection into subcutaneous tissue. With further studies, however, it became apparent that the activity attributed to phosphatidylcholine mesotherapy was due to the adipolytic effects of deoxycholate, a detergent used to solubilize phosphatidylcholine. Since then, clinical trials have surfaced that demonstrate the efficacy of a proprietary formulation of deoxycholate for local fat contouring. Current trials on mesotherapy with salmeterol, a b-adrenergic agonist and lipolysis stimulator, are underway-with promising preliminary results as well. PMID:26566569

  15. Protoplanetary and Debris Disk Morphologies

    Science.gov (United States)

    Lomax, Jamie R.; Wisniewski, John P.; Grady, Carol A.; McElwain, Michael W.; Hashimoto, Jun; Donaldson, Jessica; Debes, John H.; Malumuth, Eliot; Roberge, Aki; Weinberger, Alycia J.; SEEDS Team

    2016-01-01

    The types of planets that form around other stars are highly dependent on their natal disk conditions. Therefore, the composition, morphology, and distribution of material in protoplanetary and debris disks are important for planet formation. Here we present the results of studies of two disk systems: AB Aur and AU Mic.The circumstellar disk around the Herbig Ae star AB Aur has many interesting features, including spirals, asymmetries, and non-uniformities. However, comparatively little is known about the envelope surrounding the system. Recent work by Tang et al (2012) has suggested that the observed spiral armss may not in fact be in the disk, but instead are due to areas of increased density in the envelope and projection effects. Using Monte Carlo modeling, we find that it is unlikely that the envelope holds enough material to be responsible for such features and that it is more plausible that they form from disk material. Given the likelihood that gravitational perturbations from planets cause the observed spiral morphology, we use archival H band observations of AB Aur with a baseline of 5.5 years to determine the locations of possible planets.The AU Mic debris disk also has many interesting morphological features. Because its disk is edge on, the system is an ideal candidate for color studies using coronagraphic spectroscopy. Spectra of the system were taken by placing a HST/STIS long slit parallel to and overlapping the disk while blocking out the central star with an occulting fiducial bar. Color gradients may reveal the chemical processing that is occuring within the disk. In addition, it may trace the potential composition and architecture of any planetary bodies in the system because collisional break up of planetesimals produces the observed dust in the system. We present the resulting optical reflected spectra (5200 to 10,200 angstroms) from this procedure at several disk locations. We find that the disk is bluest at the innermost locations of the

  16. Topical agents in burn care

    OpenAIRE

    Momčilović Dragan

    2002-01-01

    Introduction Understanding of fluid shifts and recognition of the importance of early and appropriate fluid replacement therapy have significantly reduced mortality in the early post burn period. After the bum patient successfully passes the resuscitation period, the burn wound represents the greatest threat to survival. History Since the dawn of civilization, man has been trying to find an agent which would help burn wounds heal, and at the same time, not harm general condition of the injure...

  17. Building Hybrid Soft Computing Agents

    Czech Academy of Sciences Publication Activity Database

    Neruda, Roman

    Anheim : ACTA Press, 2003 - (Castillo, O.), s. 7-11 ISBN 0-88986-347-4. [IASTED International Conference on Neural Networks and Computational Intelligence. Cancun (MX), 19.05.2003-21.05.2003] R&D Projects: GA ČR(CZ) GP201/03/P163 Institutional research plan: CEZ:AV0Z1030915 Keywords : evolutionary algorithms * multi - agent system s * hybrid methods Subject RIV: BA - General Mathematics

  18. MSA AGENT FOR MULTIMEDIA APPLICATIONS

    OpenAIRE

    Aruna Rani; A. K. Gautam

    2011-01-01

    The MSA Agent is the software developed to design rectangular and U slotted micro strip antenna.It is applied for the various applications such as satellite communications, UHF applications. Within the multimedia frequency range the developed software is tested and analyzed for various results. The software is developed using genetic algorithm. This provides extra flexibility and new capability to design rectangular and U slotted micro strip antenna for multimedia application also. The result...

  19. Provably Bounded-Optimal Agents

    OpenAIRE

    Russell, S J; Subramanian, D.

    1995-01-01

    Since its inception, artificial intelligence has relied upon a theoretical foundation centered around perfect rationality as the desired property of intelligent systems. We argue, as others have done, that this foundation is inadequate because it imposes fundamentally unsatisfiable requirements. As a result, there has arisen a wide gap between theory and practice in AI, hindering progress in the field. We propose instead a property called bounded optimality. Roughly speaking, an agent is boun...

  20. Autonomous Behavior of Computational Agents

    Czech Academy of Sciences Publication Activity Database

    Vaculín, Roman; Neruda, Roman

    Wien : Springer-Verlag, 2005 - (Ribiero, B.; Albrecht, R.; Dobnikar, A.; Pearson, D.; Steele, N.), s. 514-517 ISBN 3-211-24934-6. [ICANNGA'2005 /7./. Coimbra (PT), 21.03.2005-23.03.2005] R&D Projects: GA AV ČR 1ET100300419 Institutional research plan: CEZ:AV0Z10300504 Keywords : computational agents * autonomous behavior * reasoning Subject RIV: BA - General Mathematics

  1. Agent Simulation of Chain Bankruptcy

    OpenAIRE

    Yuichi Ikeda; Yoshi Fujiwara; Wataru Souma; Hideaki Aoyama; Hiroshi Iyetomi

    2007-01-01

    We have conducted an agent-based simulation of chain bankruptcy. The propagation of credit risk on a network, i.e., chain bankruptcy, is the key to nderstanding largesized bankruptcies. In our model, decrease of revenue by the loss of accounts payable is modeled by an interaction term, and bankruptcy is defined as a capital deficit. Model parameters were estimated using financial data for 1,077 listed Japanese firms. Simulations of chain bankruptcy on the real transaction network consisting o...

  2. Crimen organizado y agente encubierto

    OpenAIRE

    Herrero Reus, Ignacio

    2014-01-01

    Uno de los objetivos de la justicia penal actual es la lucha contra la criminalidad organizada, bien por su propia naturaleza de “crimen organizado”, bien porque presenta elementos trasnacionales que impiden su investigación a fondo. Todo ello exige la creación de recursos que permitan la investigación de dichos delitos, recursos como el de infiltración de los agentes policiales, objeto del trabajo.

  3. Modern theoretical and technical approaches in plant morphology

    Directory of Open Access Journals (Sweden)

    Jürg Schönenberger

    2016-04-01

    Full Text Available Morphology is deeply rooted in organismal biology, which in recent years has gone through a steady decline in interest both at research institutions and funding agencies. In parallel with this development, morphology as a discipline has been marginalized and nowadays many think of it as just a classical and largely obsolete field of research. However, this is far from the truth. Thanks to modern theoretical concepts and novel technical applications, plant morphology has much to contribute to modern botanical and evolutionary research. In our presentation, we will first outline the application of High Resolution X-Ray Computed Tomography (HRXCT to the study of plant structure. The ideal way to describe the morphological phenotype of a given organism is to build a three dimensional (3D model, which may then be interpreted with respect to other types of data, e.g., metabolite content or functional groups of pollinators. We have developed simple but efficient lab protocols using contrasting agents such as phosphotungstate and bismuth tartrate that allow for the streamlined acquisition of high resolution phenotypic data and 3D-representations even of soft plant tissues such as floral organs, ovules, and meristematic tissues. To illustrate this, we will outline selected ongoing studies in comparative plant science that make use of high resolution tomography. In the second part of our talk, we will present a project on the floral morphospace. A striking feature of morphological variation is that due to developmental, functional, and phylogenetic constraints, not all theoretically possible architectures have been explored during evolution. A modern approach to studying the evolution of realized forms among possible ones is to construct morphospaces, i.e. theoretical, mathematical spaces describing and relating organismal phenotypes. Although widely applied in zoology, morphospace analyses and related approaches have so far been largely disregarded in

  4. Dimensions and Issues of Mobile Agent Technology

    Directory of Open Access Journals (Sweden)

    Yashpal Singh

    2012-09-01

    Full Text Available Mobile Agent is a type of software system which acts “intelligently” on one’s behalf with the feature of autonomy, learning ability and most importantly mobility. Now mobile agents are gaining interest in the research community. In this article mobile agents will be addressed as tools for mobile computing. Mobile agents have been used in applications ranging from network management to information management. We present mobile agent concept, characteristics, classification, need, applications and technical constraints in the mobile technology. We also provide a brief case study about how mobile agent is used for information retrieval.

  5. Antagonistic formation motion of cooperative agents

    Institute of Scientific and Technical Information of China (English)

    卢婉婷; 代明香; 薛方正

    2015-01-01

    This paper investigates a new formation motion problem of a class of first-order multi-agent systems with antagonis-tic interactions. A distributed formation control algorithm is proposed for each agent to realize the antagonistic formation motion. A sufficient condition is derived to ensure that all agents make an antagonistic formation motion in a distributed manner. It is shown that all agents can be spontaneously divided into several groups, and agents in the same group collab-orate while agents in different groups compete. Finally, a numerical simulation is included to demonstrate our theoretical results.

  6. Agent planning in AgScala

    Science.gov (United States)

    Tošić, Saša; Mitrović, Dejan; Ivanović, Mirjana

    2013-10-01

    Agent-oriented programming languages are designed to simplify the development of software agents, especially those that exhibit complex, intelligent behavior. This paper presents recent improvements of AgScala, an agent-oriented programming language based on Scala. AgScala includes declarative constructs for managing beliefs, actions and goals of intelligent agents. Combined with object-oriented and functional programming paradigms offered by Scala, it aims to be an efficient framework for developing both purely reactive, and more complex, deliberate agents. Instead of the Prolog back-end used initially, the new version of AgScala relies on Agent Planning Package, a more advanced system for automated planning and reasoning.

  7. A++: An Agent Oriented Programming Language

    Directory of Open Access Journals (Sweden)

    Deyi Xue

    2004-08-01

    Full Text Available A new Agent-Oriented Programming (AOP language called A++ is introduced in this research for developing agent-based distributed systems. In this work, agent-oriented programming is defined as a programming method with characteristics of distribution, autonomy, concurrency, and mobility. Both agents and objects can be modeled in A++. In addition to data and methods that can be defined in objects including classes and instances, each agent is also associated with an independent computing process in agent-oriented programming.

  8. Pharmacologic Agents for Chronic Diarrhea.

    Science.gov (United States)

    Lee, Kwang Jae

    2015-10-01

    Chronic diarrhea is usually associated with a number of non-infectious causes. When definitive treatment is unavailable, symptomatic drug therapy is indicated. Pharmacologic agents for chronic diarrhea include loperamide, 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists, diosmectite, cholestyramine, probiotics, antispasmodics, rifaximin, and anti-inflammatory agents. Loperamide, a synthetic opiate agonist, decreases peristaltic activity and inhibits secretion, resulting in the reduction of fluid and electrolyte loss and an increase in stool consistency. Cholestyramine is a bile acid sequestrant that is generally considered as the first-line treatment for bile acid diarrhea. 5-HT3 receptor antagonists have significant benefits in patients with irritable bowel syndrome (IBS) with diarrhea. Ramosetron improves stool consistency as well as global IBS symptoms. Probiotics may have a role in the prevention of antibiotic-associated diarrhea. However, data on the role of probiotics in the treatment of chronic diarrhea are lacking. Diosmectite, an absorbent, can be used for the treatment of chronic functional diarrhea, radiation-induced diarrhea, and chemotherapy-induced diarrhea. Antispasmodics including alverine citrate, mebeverine, otilonium bromide, and pinaverium bromide are used for relieving diarrheal symptoms and abdominal pain. Rifaximin can be effective for chronic diarrhea associated with IBS and small intestinal bacterial overgrowth. Budesonide is effective in both lymphocytic colitis and collagenous colitis. The efficacy of mesalazine in microscopic colitis is weak or remains uncertain. Considering their mechanisms of action, these agents should be prescribed properly. PMID:26576135

  9. Multi-agent autonomous system

    Science.gov (United States)

    Fink, Wolfgang (Inventor); Dohm, James (Inventor); Tarbell, Mark A. (Inventor)

    2010-01-01

    A multi-agent autonomous system for exploration of hazardous or inaccessible locations. The multi-agent autonomous system includes simple surface-based agents or craft controlled by an airborne tracking and command system. The airborne tracking and command system includes an instrument suite used to image an operational area and any craft deployed within the operational area. The image data is used to identify the craft, targets for exploration, and obstacles in the operational area. The tracking and command system determines paths for the surface-based craft using the identified targets and obstacles and commands the craft using simple movement commands to move through the operational area to the targets while avoiding the obstacles. Each craft includes its own instrument suite to collect information about the operational area that is transmitted back to the tracking and command system. The tracking and command system may be further coupled to a satellite system to provide additional image information about the operational area and provide operational and location commands to the tracking and command system.

  10. An Agent Based Classification Model

    CERN Document Server

    Gu, Feng; Greensmith, Julie

    2009-01-01

    The major function of this model is to access the UCI Wisconsin Breast Can- cer data-set[1] and classify the data items into two categories, which are normal and anomalous. This kind of classifi cation can be referred as anomaly detection, which discriminates anomalous behaviour from normal behaviour in computer systems. One popular solution for anomaly detection is Artifi cial Immune Sys- tems (AIS). AIS are adaptive systems inspired by theoretical immunology and observed immune functions, principles and models which are applied to prob- lem solving. The Dendritic Cell Algorithm (DCA)[2] is an AIS algorithm that is developed specifi cally for anomaly detection. It has been successfully applied to intrusion detection in computer security. It is believed that agent-based mod- elling is an ideal approach for implementing AIS, as intelligent agents could be the perfect representations of immune entities in AIS. This model evaluates the feasibility of re-implementing the DCA in an agent-based simulation environ- ...

  11. 14th International Conference on Practical Applications of Agents and Multi-Agent Systems : Special Sessions

    CERN Document Server

    Escalona, María; Corchuelo, Rafael; Mathieu, Philippe; Vale, Zita; Campbell, Andrew; Rossi, Silvia; Adam, Emmanuel; Jiménez-López, María; Navarro, Elena; Moreno, María

    2016-01-01

    PAAMS, the International Conference on Practical Applications of Agents and Multi-Agent Systems is an evolution of the International Workshop on Practical Applications of Agents and Multi-Agent Systems. PAAMS is an international yearly tribune to present, to discuss, and to disseminate the latest developments and the most important outcomes related to real-world applications. It provides a unique opportunity to bring multi-disciplinary experts, academics and practitioners together to exchange their experience in the development of Agents and Multi-Agent Systems. This volume presents the papers that have been accepted for the 2016 in the special sessions: Agents Behaviours and Artificial Markets (ABAM); Advances on Demand Response and Renewable Energy Sources in Agent Based Smart Grids (ADRESS); Agents and Mobile Devices (AM); Agent Methodologies for Intelligent Robotics Applications (AMIRA); Learning, Agents and Formal Languages (LAFLang); Multi-Agent Systems and Ambient Intelligence (MASMAI); Web Mining and ...

  12. [Dermatoglyphic morphology in some diseases].

    Science.gov (United States)

    Łopuszańska, M; Jankowska, E A

    2001-09-01

    Dermatoglyphic polymorphism results from the co-operation of genetic and environmental factors during the early stages of ontogenesis. Such elements as intrauterine viral infection, radiation, alcohol, drug or certain medicaments taken by pregnant women are able to essentially disturb the formation of dermatoglyphics, if only act before the 19th week of pregnancy. Also various genetic anomalies can result in improper morphology of ridge traits. Therefore, the dermatoglyphic analysis is a valuable completion of diagnosis of some diseases (phenyloketonuria) and syndromes genetically determined (e.g. Down, Turner or Klinefelter syndromes). Regardless of the mechanism resulting in disturbed ridge traits, the new figures of dermatoglyphics are never formed, instead the altered prevalence of particular forms of ridge traits and/or the changed direction of dermatoglyphics are revealed. The improper types of dermatoglypics--in particular when found in complexes--suggest the existence of developmental instability of an organism. PMID:11761831

  13. Filament Identification through Mathematical Morphology

    CERN Document Server

    Koch, Eric W

    2015-01-01

    We present a new algorithm for detecting filamentary structure FilFinder. The algorithm uses the techniques of mathematical morphology for filament identification, presenting a complementary approach to current algorithms which use matched filtering or critical manifolds. Unlike other methods, FilFinder identifies filaments over a wide dynamic range in brightness. We apply the new algorithm to far infrared imaging data of dust emission released by the Herschel Gould Belt Survey team. Our preliminary analysis characterizes both filaments and fainter striations. We find a typical filament width of 0.09 pc across the sample, but the brightness varies from cloud to cloud. Several regions show a bimodal filament brightness distribution, with the bright mode (filaments) being an order of magnitude brighter than the faint mode (striations). Using the Rolling Hough Transform, we characterize the orientations of the striations in the data, finding preferred directions that agree with magnetic field direction where dat...

  14. Spatially variant morphological restoration and skeleton representation.

    Science.gov (United States)

    Bouaynaya, Nidhal; Charif-Chefchaouni, Mohammed; Schonfeld, Dan

    2006-11-01

    The theory of spatially variant (SV) mathematical morphology is used to extend and analyze two important image processing applications: morphological image restoration and skeleton representation of binary images. For morphological image restoration, we propose the SV alternating sequential filters and SV median filters. We establish the relation of SV median filters to the basic SV morphological operators (i.e., SV erosions and SV dilations). For skeleton representation, we present a general framework for the SV morphological skeleton representation of binary images. We study the properties of the SV morphological skeleton representation and derive conditions for its invertibility. We also develop an algorithm for the implementation of the SV morphological skeleton representation of binary images. The latter algorithm is based on the optimal construction of the SV structuring element mapping designed to minimize the cardinality of the SV morphological skeleton representation. Experimental results show the dramatic improvement in the performance of the SV morphological restoration and SV morphological skeleton representation algorithms in comparison to their translation-invariant counterparts. PMID:17076415

  15. Scyl1 regulates Golgi morphology.

    Directory of Open Access Journals (Sweden)

    Jonathon L Burman

    Full Text Available BACKGROUND: Membrane trafficking is a defining feature of eukaryotic cells, and is essential for the maintenance of organelle homeostasis and identity. We previously identified Scy1-like 1 (Scyl1, a member of the Scy1-like family of catalytically inactive protein kinases, as a high-affinity binding partner of COPI coats. COPI-coated vesicles control Golgi to endoplasmic reticulum trafficking and we observed that disruption of Scyl1 function leads to a decrease in trafficking of the KDEL receptor via the COPI pathway. We reasoned that if Scyl1 plays a major role in COPI trafficking its disruption could influence Golgi homeostasis. METHODOLOGY/PRINCIPAL FINDINGS: We performed Scyl1 knock down in cultured cells using previously established methods and observed an alteration in Golgi morphology. Both the surface area and volume of the Golgi is increased in Scyl1-depleted cells, but the continuity and polarity of the organelle is unperturbed. At the ultrastructural level we observe a decrease in the orderly structure of the Golgi with an increase in cisternal luminal width, while the number of Golgi cisternae remains unchanged. The golgin family of proteins forms a detergent resistant network that controls Golgi homeostasis. Disruption of this protein network by knock down of the golgin p115 disrupts the Golgi localization of Scyl1. Moreover, we find that Scyl1 interacts with 58K/formiminotransferase cyclodeaminase (FTCD, a protein that is tightly associated with the cis face of the Golgi. CONCLUSIONS/SIGNIFICANCE: Our results place Scyl1 at an interface between the golgin network and COPI trafficking and demonstrate that Scyl1 is required for the maintenance of Golgi morphology. Coupled with the observation from others that Scyl1 is the gene product responsible for the neurodegenerative mouse model mdf, our results additionally implicate the regulation of COPI trafficking and Golgi homeostasis in neurodegeneration.

  16. Morphological aspects of radiation injury

    International Nuclear Information System (INIS)

    The injury to haemopoietic and lymphatic tissues produced by ionizing irradiation in various species of mammals including man is one of the major features of the biological effects of radiation (Bond et al. 1965,' Cottier, 1961). At the moment of injury and for a short time thereafter relatively little morphological evidence of cell damage in bone marrow other than cessation of cell division and DNA synthesis is seen. Within a few hours, however, depending on the level of exposure, major destruction of red bone marrow tissue can occur. In this chapter the histologic changes in bone marrow are summarized for correlation with the functional aspects of the change in the target tissue, particularly its cell renewal features and where possible the remarkable flux or migration of cells through bone marrow and lymphatic tissues. This latter topic of cellular traffic represents the outcome of extensive physiological studies on haemopoiesis and lymphopoiesis by mammalian radiobiologists. The initial injury, the structural changes and the physiological consequences are the first half of the radiation injury sequence. Regeneration also has morphological features of major importance to the understanding of radiation haematology. It is common to discuss radiation effects on biological materials from the point of view of external or internal sources of exposure. In addition exposure rate, whole body or partial body, type and quality of the ionizing source are features that must be taken into account. While these features are extremely important, the simplest approach to understanding histologic effects on the bone marrow is to assume acute penetrating whole-body exposure in the lethal range. With this background the differences related to variations in the conditions of exposure can usually be understood. The individual human or animal organism receiving the exposure must also be considered in the final outcome of the experience because age, sex, nutritional status and presence

  17. Prediction of mountain stream morphology

    Science.gov (United States)

    Wohl, Ellen; Merritt, David

    2005-08-01

    We use a large and diverse data set from mountain streams around the world to explore relationships between reach-scale channel morphology and control variables. The data set includes 177 step-pool reaches, 44 plane-bed reaches, and 114 pool-riffle reaches from the western United States, Panama, and New Zealand. We performed several iterations of stepwise discriminant analysis on these data. A three-variable discriminant function using slope (S), D84, and channel width (w) produced an error rate of 24% for the entire data set. Seventy percent of plane-bed reaches were correctly classified (16% incorrectly classified as pool-riffle and 14% incorrectly classified as step-pool). Sixty-seven percent of pool-riffle channels were correctly classified (31% incorrectly classified as plane-bed and 2% as step-pool). Eighty-nine percent of step-pool reaches were correctly classified (9% incorrectly classified as plane-bed and 2% as pool-riffle). The partial R2 values and F tests indicate that S is by far the most significant single explanatory variable. Comparison of the eight discriminant functions developed using different data sets indicates that no single variable is present in all functions, suggesting that the discriminant functions are sensitive to the specific stream reaches being analyzed. However, the three-variable discriminant function developed from the entire data set correctly classified 69% of the 159 channels included in an independent validation data set. The ability to accurately classify channel type in other regions using the three-variable discriminant function developed from the entire data set has important implications for water resources management, such as facilitating prediction of channel morphology using regional S-w-D84 relations calibrated with minimal field work.

  18. Optimization of dispersing agents for preparing YAG transparent ceramics

    Institute of Scientific and Technical Information of China (English)

    BA Xuewei; LI Jiang; PAN Yubai; LIU Jing; JIANG Benxue; LIU Wenbin; KOU Huamin

    2013-01-01

    The suspensions of the powder mixture of yttria and alumina were prepared by the aqueous tape casting method.Rodia DP270,Dolapix CE64,citric acid and Dammonium 3008 were used as dispersing agents.The morphologies of the powders and the fiacture surface of the green body were observed by scanning electron microscopy (SEM).The zeta potential test was employed to characterize the surface charge states of different suspensions.The dispersion of the suspensions was analyzed by the rheological tests and the sedimentation experiments.The results indicated that the yttria and alumina powder mixtures were well dispersed by the dispersing agents.The rheological curves showed shear thinning behavior.The most efficient dispersing agent was Dammonium 3008.The optimum usage of Dammonium 3008 was 1.0 wt.%.The green body was dense and no interface between the adjacent layers was found.The in-line transmittance of the as-sintered YAG ceramic was higher than 80% between 400 and 1100 nm.

  19. Borrelioses, agentes e vetores Borrelioses, agents and vectors: a review

    Directory of Open Access Journals (Sweden)

    Cleber O. Soares

    2000-03-01

    Full Text Available As borrelioses são enfermidades infecciosas determinadas por espiroquetas do gênero Borrelia, agentes transmissíveis, principalmente, por carrapatos aos animais e/ou ao homem. Nesta revisão são apresentadas e discutidas as enfermidades determinadas por borrélias, bem como as características gerais das espiroquetas, os aspectos relacionados a transmissão por artrópodes, as enfermidades nos animais domésticos e silvestres, quanto aos aspectos biológicos e patológicos, a doença de Lyme como principal zoonose do grupo, a associação de borrélia com outros agentes hematozoários e os métodos diagnósticos e a epidemiologia comparativa entre dados obtidos no Brasil com os de outros países. Estas borrelioses possuem características patológicas, clínicas e epidemiológicas variadas de acordo à região fisiográfica, devido à existência de distintas espécies, genoespécies e cepas; estes aspectos variam ainda em função dos artrópodes vetores, da interação vetor-patógeno e dos ecossistemas distintos.Borrelioses are infectous diseases caused by spirochaetes of the genus Borrelia. They are born mainly through ticks at animals and/or human beings. In this review are shown and discussed five groups of diseases determined by borrelia, general characteristics of the spirochaetes, aspects related to transmission by arthropods, biological and pathological aspects of the diseases in domestic and wild animals, Lyme disease as an important zoonosis, the association of borrelia with other hematozoa agents, the diagnostic methods and the comparative epidemiology with data obtained from Brazil and other countries. The borrelioses have pathological, clinical and epidemiological characteristics which vary according to physiographic regions due to the existence of different species, genospecies and strains of borrelia, of arthropod vectors, vector-agent relationship and of different ecocystems.

  20. Automatic quantitative morphological analysis of interacting galaxies

    CERN Document Server

    Shamir, Lior; Wallin, John

    2013-01-01

    The large number of galaxies imaged by digital sky surveys reinforces the need for computational methods for analyzing galaxy morphology. While the morphology of most galaxies can be associated with a stage on the Hubble sequence, morphology of galaxy mergers is far more complex due to the combination of two or more galaxies with different morphologies and the interaction between them. Here we propose a computational method based on unsupervised machine learning that can quantitatively analyze morphologies of galaxy mergers and associate galaxies by their morphology. The method works by first generating multiple synthetic galaxy models for each galaxy merger, and then extracting a large set of numerical image content descriptors for each galaxy model. These numbers are weighted using Fisher discriminant scores, and then the similarities between the galaxy mergers are deduced using a variation of Weighted Nearest Neighbor analysis such that the Fisher scores are used as weights. The similarities between the ga...

  1. Recent Advances in Morphological Cell Image Analysis

    Directory of Open Access Journals (Sweden)

    Shengyong Chen

    2012-01-01

    Full Text Available This paper summarizes the recent advances in image processing methods for morphological cell analysis. The topic of morphological analysis has received much attention with the increasing demands in both bioinformatics and biomedical applications. Among many factors that affect the diagnosis of a disease, morphological cell analysis and statistics have made great contributions to results and effects for a doctor. Morphological cell analysis finds the cellar shape, cellar regularity, classification, statistics, diagnosis, and so forth. In the last 20 years, about 1000 publications have reported the use of morphological cell analysis in biomedical research. Relevant solutions encompass a rather wide application area, such as cell clumps segmentation, morphological characteristics extraction, 3D reconstruction, abnormal cells identification, and statistical analysis. These reports are summarized in this paper to enable easy referral to suitable methods for practical solutions. Representative contributions and future research trends are also addressed.

  2. Development of polypropylene/wood flour ecocomposites. Evaluation of silane as coupling agent

    Science.gov (United States)

    Bouza, R.; Barral, L.; Abad, M. J.; Montero, B.

    2010-06-01

    The effects of Pinus Sylvestris wood flour as filler in polypropylene matrix was evaluated. The mechanical properties and the morphology of different wood flour/polypropylene composites (WPC) were studied. The composites materials were prepared with several amounts of wood flour from 10 to 30% wt. Mechanical properties show that the wood flour incorporation increases the rigidity of the composites. Morphological analysis indicates that agglomerates are formed, with amounts exceeding 30% of wood flour. For the silane—treated composites, the dispersion of the filler into the polypropylene (PP) matrix improved. Shore D hardness of the composites is decreased with the addition of the coupling agent.

  3. Learning other agents` preferences in multiagent negotiation

    Energy Technology Data Exchange (ETDEWEB)

    Bui, H.H.; Kieronska, D.; Venkatesh, S. [Curtin Univ. of Technology, Perth, WA (Australia)

    1996-12-31

    In multiagent systems, an agent does not usually have complete information about the preferences and decision making processes of other agents. This might prevent the agents from making coordinated choices, purely due to their ignorance of what others want. This paper describes the integration of a learning module into a communication-intensive negotiating agent architecture. The learning module gives the agents the ability to learn about other agents` preferences via past interactions. Over time, the agents can incrementally update their models of other agents` preferences and use them to make better coordinated decisions. Combining both communication and learning, as two complement knowledge acquisition methods, helps to reduce the amount of communication needed on average, and is justified in situations where communication is computationally costly or simply not desirable (e.g. to preserve the individual privacy).

  4. Agent Communication Channel Based on BACnet

    Institute of Scientific and Technical Information of China (English)

    Jiang Wen-bin; Zhou Man-li

    2004-01-01

    We analyze the common shortcoming in the existing agent MTPs (message transport protocols). With employing the File object and related service AtomicWriteFile of BACnet (a data communication protocol building automation and control networks), a new method of agent message transport is proposed and implemented. Every agent platform (AP) has one specified File object and agents in another AP can communicate with agents in the AP by using AtomicWriteFile service. Agent messages can be in a variety of formats. In implementation, BACnet/IP and Ethernet are applied as the BACnet data link layers respectively. The experiment results show that the BACnet can provide perfect support for agent communication like other conventional protocols such as hypertext transfer protocol(HTTP), remote method invocation (RMI) etc. and has broken through the restriction of TCP/IP. By this approach, the agent technology is introduced into the building automation control network system.

  5. Analysis and Optimization for Mobile Agent Communication

    Institute of Scientific and Technical Information of China (English)

    YANGBo; LIUDayou

    2005-01-01

    Communication performance is one of the most important factors affecting the efficiency of mobile agent system. Only traditional optimization techniques for communication performance are not enough, especially in large-scale intelligent mobile agent system, so more intelligent optimization techniques are needed. In the background, the paper studies communication of mobile agent system from the viewpoint of performance. The paper makes qualitative and quantitative analysis of four important factors that will affect the communication performance of mobile agent system and presents the communication performance optimization model. The model hasthree primary functions. First, the model provides a formalism method to describe the communication task and process of mobile agent. Second, the model provides a means to make quantitative analysis of the performance of mobile agent system. Third, the model can plan out an optimal communication scheme for mobile agent to minimize the cost of whole communication. The model could thus be a building block for the optimization of the communication behavior of mobile agent.

  6. Comparison of Communication Models for Mobile Agents

    Directory of Open Access Journals (Sweden)

    Xining Li

    2003-04-01

    Full Text Available An agent is a self-contained process being acting on behalf of a user. A Mobile Agent is an agent roaming the internet to access data and services, and carry out its assigned task remotely. This paper will focus on the communication models for Mobile Agents. Generally speaking, communication models concern with problems of how to name Mobile Agents, how to establish communication relationships, how to trace moving agents, and how to guarantee reliable communication. Some existing MA systems are purely based on RPC-style communication, whereas some adopts asynchronous message passing, or event registration/handling. Different communication concepts suitable for Mobile Agents are well discussed in [1]. However, we will investigate these concepts and existing models from a different point view: how to track down agents and deliver messages in a dynamic, changing world.

  7. A Framework for Multi-Agent Planning

    OpenAIRE

    Bos, A; Tonino, J.F.M.; De Weerdt, M.M.; Witteveen, C.

    2000-01-01

    We introduce a computational framework, consisting of resources, skills, goals and services to represent the plans of individual agents and to develop models and algorithms for cooperation processes between a collection of agents.

  8. Porphyria Cutanea Tarda and Agent Orange

    Science.gov (United States)

    ... ZIP code here Porphyria Cutanea Tarda and Agent Orange VA presumes porphyria cutanea tarda (PCT) is related to Veterans' exposure to Agent Orange or other herbicides during military service when the ...

  9. Soft Tissue Sarcomas and Agent Orange

    Science.gov (United States)

    ... ZIP code here Soft Tissue Sarcomas and Agent Orange VA presumes some soft tissue sarcomas in Veterans are related to their exposure to Agent Orange or other herbicides during military service. The soft ...

  10. Morphology and activity of vanadium-containing catalysts for the selective oxidation of benzene to maleic anhydride

    Science.gov (United States)

    Dosumov, K.; Ergazieva, G. E.

    2012-11-01

    The morphology and activity of vanadium catalysts are studied using a number of physicochemical methods: electron microscopy, electron paramagnetic resonance, and infrared spectroscopy. It is found that the active agent of the conversion of benzene to maleic anhydride over modified vanadium catalysts is the V4+ ion in the vanadyl configuration.

  11. Galaxy morphology - an unsupervised machine learning approach

    OpenAIRE

    Schutter, Andrew; Shamir, Lior

    2015-01-01

    Structural properties posses valuable information about the formation and evolution of galaxies, and are important for understanding the past, present, and future universe. Here we use unsupervised machine learning methodology to analyze a network of similarities between galaxy morphological types, and automatically deduce a morphological sequence of galaxies. Application of the method to the EFIGI catalog show that the morphological scheme produced by the algorithm is largely in agreement wi...

  12. Deterministic mathematical morphology for CAD/CAM

    OpenAIRE

    Sarabia Pérez, Rubén; Jimeno Morenilla, Antonio; Molina Carmona, Rafael

    2014-01-01

    Purpose – The purpose of this paper is to present a new geometric model based on the mathematical morphology paradigm, specialized to provide determinism to the classic morphological operations. The determinism is needed to model dynamic processes that require an order of application, as is the case for designing and manufacturing objects in CAD/CAM environments. Design/methodology/approach – The basic trajectory-based operation is the basis of the proposed morphological specialization. This ...

  13. PREPARATION OF POLYALKYLCYANOACRYLATE NANOPARTICLES WITH VARIOUS MORPHOLOGIES

    Institute of Scientific and Technical Information of China (English)

    Qing-lin Xu; He-xian Li; Guo-chang Wang

    2011-01-01

    The effects of various reaction conditions on the preparation of polyalkylcyanoacrylate (PACA) nanoparticles are studied. The PACA nanoparticles with different crosslinking degrees and morphology are prepared. Addition of crosslinkers can not only adjust the particle size, but also change the morphology of PACA nanoparticles. Moreover, the loose network structure of the PACA nanoparticles with “core/shell-like” morphology is investigated by AFM and TEM in detail.

  14. Morphological changes during annealing of polyethylene nanocrystals

    OpenAIRE

    Basu, Nandita; Osichow, Anna; Mecking, Stefan; Reiter, Günter

    2012-01-01

    Polymer crystals are metastable and exhibit morphological changes when being annealed. To observe morphological changes on molecular scales we started from small nanometer-sized crystals of highly folded long-chain polymers. Micron-sized stripes consisting of monolayers or stacks of several layers of flat-on oriented polyethylene nanocrystals were generated via evaporative dewetting from an aqueous dispersion. We followed the morphological changes in time and at progressively higher annealing...

  15. Mobile agents for distributed decision support systems

    OpenAIRE

    Blaz Rodič

    2011-01-01

    This article focuses on the performance of Java based mobile agents using format translation via an intermediary XML based format. Our goal was to develop and verify the performance of a lightweight, mobile agent based solution that would allow strong security, portability and access to heterogeneous data resources from a mobile platform to facilitate exchange of data between simulation models and data resources. We have developed two types of agents: a mobile agent that functions as a server...

  16. Security Issues in Mobile Agent Paradigm

    OpenAIRE

    Nitin Jain; Neeraj Singla

    2011-01-01

    A mobile Agent is a Software program that migrates from node tonode of a heterogeneous network. They are goal-oriented i.e. workautonomously towards a goal, capable of suspending their executionon one platform and moving to other where they can resumeexecution using resources of these nodes and they meet and interactwith other agents. Agents may be stationary, always resident at asingle platform or mobile, capable of moving among differentplatforms at different time. The mobile agent paradigm...

  17. Explaining Simulations Through Self Explaining Agents

    OpenAIRE

    Maaike Harbers; John-Jules Meyer; Karel Van den Bosch

    2010-01-01

    Several strategies are used to explain emergent interaction patterns in agent-based simulations. A distinction can be made between simulations in which the agents just behave in a reactive way, and simulations involving agents with also pro-active (goal-directed) behavior. Pro-active behavior is more variable and harder to predict than reactive behavior, and therefore it might be harder to explain. However, the approach presented in this paper tries to make advantage of the agents' pro-active...

  18. ENZYMATIC DEINKING AGENTS FOR MIXED OFFICE WASTEPAPER

    Institute of Scientific and Technical Information of China (English)

    HuayuQiu; ChuanfuLiu; XiaokeMa; YingjuanFu

    2004-01-01

    This article focused on deinking agents for enzymatic deinking of MOW (mixed office wastepaper). The deinking performances of many series of surfactants were discussed at the experimental conditions, and finally some surfactants, which had good deinking effect, were selected. Then two-composed deinking agents were discussed. The deinkability of the deinking agents, e.g. deinking agents containing T-123 50% and P-10 50%, T-123 70% and O-15 30%, were better than that of the imported product.

  19. ENZYMATIC DEINKING AGENTS FOR MIXED OFFICE WASTEPAPER

    Institute of Scientific and Technical Information of China (English)

    Huayu Qiu; Chuanfu Liu; Xiaoke Ma; Yingjuan Fu

    2004-01-01

    This article focused on deinking agents for enzymatic deinking of MOW (mixed office wastepaper). The deinking performances of many series of surfactants were discussed at the experimental conditions, and finally, some surfactants, which had good deinking effect, were selected. Then two-composed deinking agents were discussed. The deinkability of the deinking agents, e.g. deinking agents containing T-123 50% and P-10 50%, T-123 70% and O-1530%, were better than that of the imported product.

  20. Virtual Knowledge Communities for Semantic Agents

    OpenAIRE

    Subercaze, Julien; Maret, Pierre

    2011-01-01

    International audience Virtual Knowledge Communities are a well suited paradigm for decentralized knowldege exchanges and they have been applied in several domains. In this paper we investigate the implementation of virtual knowledge communities with se- mantic agents. Using the SAM (Semantic Agent Modeling) approach, we show that agents can exchange community re- lated concepts (in OWL) and behavior (in SWRL). Agents can then learn and adapt new community-related behavior, which is useful...

  1. On Programming Organization-Aware Agents

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt

    Since it is difficult (or even impossible) to assume anything about the agents’ behavior and goals in an open multi-agent system, it is often suggested that an organization is imposed upon the agents, whichhich, by abstracting away from the agents, specifies boundaries and objectives that the......-aware, thus removing the middleware and letting the agents directly reason about the organization. In this paper, we discuss the results so far, and describe the future goals and research direction for the project....

  2. Sports Agent Industry Emerges in China

    Institute of Scientific and Technical Information of China (English)

    HeiZiand; YiYou

    2003-01-01

    The agent profession is not new to Chinese. First appearing in the Western Zhou Dynasty, agents were called "Zhi Ren" then and "Ya Ren" from the Tang Dynasty onwards. In the Ming Dynasty, a certain amount of property and a license were required if one wanted to become an agent. In the late Qing Dynasty, Mai Ban (Chinese executives working in foreign firms), also a sort of agents, began to emerge in major cities of China.

  3. Integration of Agent System with Legacy Software

    Institute of Scientific and Technical Information of China (English)

    SHEN Qi; ZHAO Yan-hong; YIN Zhao-lin

    2003-01-01

    Agent technique is a new method that can analyze, design and realize a distributed open system. It has been used in almost every field. But if act for the real practical words in technique, it must integrate with legacy software, such as database system etc, and control them. This paper introduces the specification of agent software integration, ontology, instances database as implementing agent software integration with CORBA technique and takes XML, ACL as language communicating among agents.

  4. Topology and Social Behaviour of Agents

    OpenAIRE

    O. Hudak

    2003-01-01

    In a social group its members are caled here agents. Any two agents from the group may interact. The interaction consists of the exchange of information and it costs some energy. There exist subgroups of interacting agents which are nonreducibile. The structure, configuration of interactions between agents in the group, forms a macroscopic structure. The statistical equilibrium due to microreversibility is characterised by the maximum of entropy and by the minimum of energy, costs of informat...

  5. Self-Adapting Reactive Autonomous Agents

    Science.gov (United States)

    Andrecut, M.; Ali, M. K.

    This paper describes a new self-adapting control algorithm for reactive autonomous agents. The architecture of the autonomous agents integrates the reactive behavior with reinforcement learning. We show how these components perform on-line adaptation of the autonomous agents to various complex navigation situations by constructing an internal model of the environment. Also, a discussion on cooperation and coordination of teams of agents is presented.

  6. Morphology of Experimental Impact Craters into Sandstone

    Science.gov (United States)

    Dufresne, A.; Poelchau, M. H.; Kenkmann, T.; Deutsch, A.; Hoerth, T.; Schaefer, F.

    2012-03-01

    Detailed morphometric crater analyses of hypervelocity impact experiments were carried out to investigate the influence of impact velocity and target pore space saturation on crater size and morphology.

  7. The limits on trypanosomatid morphological diversity.

    Directory of Open Access Journals (Sweden)

    Richard John Wheeler

    Full Text Available Cell shape is one, often overlooked, way in which protozoan parasites have adapted to a variety of host and vector environments and directional transmissions between these environments. Consequently, different parasite life cycle stages have characteristic morphologies. Trypanosomatid parasites are an excellent example of this in which large morphological variations between species and life cycle stage occur, despite sharing well-conserved cytoskeletal and membranous structures. Here, using previously published reports in the literature of the morphology of 248 isolates of trypanosomatid species from different hosts, we perform a meta-analysis of the occurrence and limits on morphological diversity of different classes of trypanosomatid morphology (trypomastigote, promastigote, etc. in the vertebrate bloodstream and invertebrate gut environments. We identified several limits on cell body length, cell body width and flagellum length diversity which can be interpreted as biomechanical limits on the capacity of the cell to attain particular dimensions. These limits differed for morphologies with and without a laterally attached flagellum which we suggest represent two morphological superclasses, the 'juxtaform' and 'liberform' superclasses. Further limits were identified consistent with a selective pressure from the mechanical properties of the vertebrate bloodstream environment; trypanosomatid size showed limits relative to host erythrocyte dimensions. This is the first comprehensive analysis of the limits of morphological diversity in any protozoan parasite, revealing the morphogenetic constraints and extrinsic selection pressures associated with the full diversity of trypanosomatid morphology.

  8. Properties of Ettringite Type Expansive Agent

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    By employing different forms and amounts of materials,many kinds of ettringite type expansive agents had been prepared.The relationship between the compositions and properties of expansive agents was analyzed.The design methods of expansive agent have been put forward according to the property requirement of expansive concrete.

  9. Agent for roentgenocontrast examination of cavities

    International Nuclear Information System (INIS)

    The water-soluble agent, additionaly containing starch, agar, water, is suggested to increase accuracy of injured cavity diagnostics. The method for roentgenocontrast agent preparation on the base of starch-agar gel is described. Advantages of the agent suggested in comparison with those of roentgenologic cavity investigation used are shown

  10. Cooperative heuristic multi-agent planning

    NARCIS (Netherlands)

    De Weerdt, M.M.; Tonino, J.F.M.; Witteveen, C.

    2001-01-01

    In this paper we will use the framework to study cooperative heuristic multi-agent planning. During the construction of their plans, the agents use a heuristic function inspired by the FF planner (l3l). At any time in the process of planning the agents may exchange available resources, or they may r

  11. Stability of Evolving Multi-Agent Systems

    CERN Document Server

    De Wilde, Philippe; 10.1109/TSMCB.2011.2110642

    2011-01-01

    A Multi-Agent System is a distributed system where the agents or nodes perform complex functions that cannot be written down in analytic form. Multi-Agent Systems are highly connected, and the information they contain is mostly stored in the connections. When agents update their state, they take into account the state of the other agents, and they have access to those states via the connections. There is also external, user-generated input into the Multi-Agent System. As so much information is stored in the connections, agents are often memory-less. This memory-less property, together with the randomness of the external input, has allowed us to model Multi-Agent Systems using Markov chains. In this paper, we look at Multi-Agent Systems that evolve, i.e. the number of agents varies according to the fitness of the individual agents. We extend our Markov chain model, and define stability. This is the start of a methodology to control Multi-Agent Systems. We then build upon this to construct an entropy-based defi...

  12. The Ontogenesis of Agent: Linguistic Expression.

    Science.gov (United States)

    Olswang, Lesley Barrett; Carpenter, Robert L.

    1982-01-01

    Some of the findings of a longitudinal study of three infants between their 11th and 22nd months to document development of linguistic expression of the agent concept indicated that first vocalizations were inconsistently associated with nonverbal agentive behaviors and later mature utterances coded agent-action-recipient events. (MC)

  13. Embedded Automation in Human-Agent Environment

    CERN Document Server

    Tweedale, Jeffrey W

    2012-01-01

    This research book proposes a general conceptual framework for the development of automation in human-agents environments that will allow human- agent teams to work effectively and efficiently. We examine various schemes to implement artificial intelligence techniques in agents.  The text is directed to the scientists, application engineers, professors and students of all disciplines, interested in the agency methodology and applications.

  14. STUDIES OF WATERBORNE AGENTS OF VIRAL GASTROENTERITIS

    Science.gov (United States)

    The etiologic agent of a large outbreak of waterborne viral gastroenteritis was detected employing immune electron microscopy (IEM) and a newly developed solid phase radioimmunoassay (RIA). This agent, referred to as the Snow Mountain Agent (SMA), is 27-32 nm. in diameter, has cu...

  15. A theoretical framework for explaining agent behavior

    NARCIS (Netherlands)

    Harbers, M.; Bosch, K. van den; Meyer, J.J.C.

    2011-01-01

    To understand emergent processes in multi-agent-based simulations it is important to study the global processes in a simulation as well as the processes on the agent level. The behavior of individual agents is easier to understand when they are able to explain their own behavior. In this paper, a th

  16. Stigmergy in multi-agent reinforcement learning

    OpenAIRE

    Aras, Raghav; Dutech, Alain; Charpillet, François

    2004-01-01

    http://www.computer.org In this paper, we describe how certain aspects of the biological phenomena of stigmergy can be imported into multi-agent reinforcement learning (MARL), with the purpose of better enabling coordination of agent actions and speeding up learning. In particular, we detail how these stigmergic aspects can be used to define an inter-agent communication framework.

  17. Explaining simulations through self explaining agents

    NARCIS (Netherlands)

    Harbers, M.; Bosch, K. van den; Meyer, J.J.C.

    2010-01-01

    Several strategies are used to explain emergent interaction patterns in agent-based simulations. A distinction can be made between simulations in which the agents just behave in a reactive way, and simulations involving agents with also pro-active (goal-directed) behavior. Pro-active behavior is mor

  18. Explaining Simulations through Self Explaining Agents

    NARCIS (Netherlands)

    Harbers, M.; Dignum, F.; Bosch, K. van den; Meyer, J.J.C.

    2008-01-01

    Several strategies are used to explain emergent interaction patterns in agent-based simulations. A distinction can be made between simulations in which the agents just behave in a reactive way, and simulations involving agents with also pro-active (goal-directed) behavior. Pro-active behavior is mor

  19. Mobile Agents in Networking and Distributed Computing

    CERN Document Server

    Cao, Jiannong

    2012-01-01

    The book focuses on mobile agents, which are computer programs that can autonomously migrate between network sites. This text introduces the concepts and principles of mobile agents, provides an overview of mobile agent technology, and focuses on applications in networking and distributed computing.

  20. On Programming Organization-Aware Agents

    DEFF Research Database (Denmark)

    Jensen, Andreas Schmidt

    2013-01-01

    Since it is difficult (or even impossible) to assume anything about the agents’ behavior and goals in an open multi-agent system, it is often suggested that an organization is imposed upon the agents, whichhich, by abstracting away from the agents, specifies boundaries and objectives that the age...

  1. Radioactive scanning agents with hydroquinone stabilizer

    International Nuclear Information System (INIS)

    Stable compositions useful as technetium 99m-based scintigraphic agents comprise hydroquinone in combination with a pertechnetate reducing agent or dissolved in pertechnetate-99m (sup(99m)TcOsub(4)sup(-)) solution. The compositions are especially useful in combination with a phosphate or phosphonate material which carries the radionuclide to bone, thus providing a skeletal imaging agent

  2. Honey - A Novel Antidiabetic Agent

    Directory of Open Access Journals (Sweden)

    Omotayo O. Erejuwa, Siti A. Sulaiman, Mohd S. Ab Wahab

    2012-01-01

    Full Text Available Diabetes mellitus remains a burden worldwide in spite of the availability of numerous antidiabetic drugs. Honey is a natural substance produced by bees from nectar. Several evidence-based health benefits have been ascribed to honey in the recent years. In this review article, we highlight findings which demonstrate the beneficial or potential effects of honey in the gastrointestinal tract (GIT, on the gut microbiota, in the liver, in the pancreas and how these effects could improve glycemic control and metabolic derangements. In healthy subjects or patients with impaired glucose tolerance or diabetes mellitus, various studies revealed that honey reduced blood glucose or was more tolerable than most common sugars or sweeteners. Pre-clinical studies provided more convincing evidence in support of honey as a potential antidiabetic agent than clinical studies did. The not-too-impressive clinical data could mainly be attributed to poor study designs or due to the fact that the clinical studies were preliminary. Based on the key constituents of honey, the possible mechanisms of action of antidiabetic effect of honey are proposed. The paper also highlights the potential impacts and future perspectives on the use of honey as an antidiabetic agent. It makes recommendations for further clinical studies on the potential antidiabetic effect of honey. This review provides insight on the potential use of honey, especially as a complementary agent, in the management of diabetes mellitus. Hence, it is very important to have well-designed, randomized controlled clinical trials that investigate the reproducibility (or otherwise of these experimental data in diabetic human subjects.

  3. Morphological similarities between DBM and a microeconomic model of sprawl

    Science.gov (United States)

    Caruso, Geoffrey; Vuidel, Gilles; Cavailhès, Jean; Frankhauser, Pierre; Peeters, Dominique; Thomas, Isabelle

    2011-03-01

    We present a model that simulates the growth of a metropolitan area on a 2D lattice. The model is dynamic and based on microeconomics. Households show preferences for nearby open spaces and neighbourhood density. They compete on the land market. They travel along a road network to access the CBD. A planner ensures the connectedness and maintenance of the road network. The spatial pattern of houses, green spaces and road network self-organises, emerging from agents individualistic decisions. We perform several simulations and vary residential preferences. Our results show morphologies and transition phases that are similar to Dieletric Breakdown Models (DBM). Such similarities were observed earlier by other authors, but we show here that it can be deducted from the functioning of the land market and thus explicitly connected to urban economic theory.

  4. Anticancer agents from marine sponges.

    Science.gov (United States)

    Ye, Jianjun; Zhou, Feng; Al-Kareef, Ammar M Q; Wang, Hong

    2015-01-01

    Marine sponges are currently one of the richest sources of anticancer active compounds found in the marine ecosystems. More than 5300 different known metabolites are from sponges and their associated microorganisms. To survive in the complicated marine environment, most of the sponge species have evolved chemical means to defend against predation. Such chemical adaptation produces many biologically active secondary metabolites including anticancer agents. This review highlights novel secondary metabolites in sponges which inhibited diverse cancer species in the recent 5 years. These natural products of marine sponges are categorized based on various chemical characteristics. PMID:25402340

  5. Social Robots as Persuasive Agents

    DEFF Research Database (Denmark)

    Vlachos, Evgenios; Schärfe, Henrik

    2014-01-01

    Robots are more and more used in a social context, and in this paper we try to formulate a research agenda concerning ethical issues around social HRI in order to be prepared for future scenarios where robots may be a naturally integrated part of human society. We outline different paradigms to d...... describe the role of social robots in communication processes with humans, and connect HRI with the topic of persuasive technology in health care, to critically reflect the potential benefits of using social robots as persuasive agents....

  6. Secular trend: morphology and performance.

    Science.gov (United States)

    Sedeaud, Adrien; Marc, Andy; Schipman, Julien; Schaal, Karine; Danial, Mario; Guillaume, Marion; Berthelot, Geoffroy; Toussaint, Jean-François

    2014-01-01

    In a context of morphological expansion of the general population, how do athletes follow such a pattern of anthropometric growth? Is there any relation to performance? Biometric data including mass, height, body mass index (BMI) and age were collected for 50,376 American athletes representing 249,336 annual performers playing in professional baseball, football, ice hockey and basketball. Distributions by mass in National Football League (NFL) players are described by periods. Field goals have been studied in relation to players' height in the National Basketball Association (NBA). Between 1871 and 2011, athletes from the four sports have increased significantly in mass, height and BMI, following a multi-exponential function series. Consequently, biometric differences between athletes and the general population are increasing gradually. Changes in the mass distribution within the NFL show the emergence of a biometrical specificity in relation to the field position. At the professional level, performance remains structured around precise biometric values. In the NBA, a height-attractor at 201.3 ± 6.3 cm for the best scorers is invariant, regardless of the level of play. These results suggest that laws of growth and biometrics drive high-level sport and organise performance around the specific constraint of each field position. Discrepancies between some mass and height developments question the (disproportionate) large mass increase (relative to the height increase) during the 1980s and 1990s. PMID:24580142

  7. Mechanical analysis of eyelid morphology.

    Science.gov (United States)

    Zhu, Liangliang; Chen, Xi

    2013-08-01

    From a mechanical instability perspective a double eyelid is a double-folded thin film structure on a curved substrate, caused by compression as the film "slides" on the substrate. The underlying mechanics issues, in particular the requirements for forming a double folded structure, are studied using a modeling/simulation framework. A minimalist model is employed to explore the wrinkle to fold transition. Refined and enriched models are further developed based on anatomical structures, which demonstrate three critical factors for the formation of double layer folding of the eyelid. First, a crease line in the eyelid is essential where the local bending rigidity is relatively weak. Second, the skin above the crease line should be thin and wide enough. Third, the skin below the crease line should have a relatively large effective stiffness so it can be lifted as a whole when the eyes open. When the eye is opened beyond about 40% of its initial wrinkle wavelength, the double-folded structure emerges. Various types of eyelid morphologies are discussed based on the mechanistic model. The study provides useful insights for surgery, cosmetics, and morphogenesis, as well as microfabrication. PMID:23597858

  8. SEGMENTATION USING MULTISCALE MORPHOLOGICAL RECONSTRUCTION

    Directory of Open Access Journals (Sweden)

    NANMOZHI.R

    2013-04-01

    Full Text Available Image segmentation is a crucial step in the field of image processing and pattern recognition. Segmentation allows the identification of structures in an image which can be utilized for further processing. This paper proposes a technique for object segmentation from its background. We utilized both region-based and object-based segmentation capabilities to handle the object segmentation for large-scale database images in a robust and principled manner. MultiScalE Graylevel mOrphological recoNstructions (SEGON is used for segmenting an image. SEGON roughly identifies the background and object regions in the image. To further refine the boundaries of the objects mean-shift segmentation technique is applied on the SEGON processed image. Accuracy of segmentation is evaluated by computing structural similarity index (SSIM, for the image segmented with and without using SEGON. Images collected from Corel, Caltech, PASCAL, UCID and CMU-PIE databases are utilized for this work. Experimental results showed that the proposed object segmentation method outperforms the state-of-the-art image segmentation techniques.

  9. Camouflaging Agents for Vitiligo Patients.

    Science.gov (United States)

    Hossain, Claudia; Porto, Dennis A; Hamzavi, Iltefat; Lim, Henry W

    2016-04-01

    Vitiligo is an acquired condition resulting in patches of depigmented skin that is cosmetically disfiguring and can subsequently be psychologically disturbing. For patients seeking to mask their vitiligo, camouflage options have historically been limited and been designated as a cosmetic, rather than a medical, concern. As research has indicated that proper concealment of vitiligo lesions can vastly improve quality of life, we believe it is essential that dermatologists become aware of all the options available to their patients and that discussions of camouflage options be broached from the first visit. Methods for concealment include cosmetic tattoos, dihydroxyacetone, general cosmetics, and various topical camouflage agents, including the newest product, Microskin™. We conducted a literature review of all of the available options for vitiligo concealment and evaluated their advantages and disadvantages. Ultimately, temporary methods of concealment are recommended; but the particular agent used can come from discussion with the patient based on the location of the lesions, degree of concealment desired, cost, and availability. PMID:27050692

  10. Surfactants as blackbird stressing agents

    Science.gov (United States)

    Lefebvre, P.W.; Seubert, J.L.

    1970-01-01

    Applications of wetting-agent solutions produce mortality in birds. The exact cause of death is undetermined but it is believed that destruction of the insulating qualities of the plumage permits ambient cold temperatures and evaporation to lower the body temperature to a lethal level. The original concept of using these materials as bird-control tools was developed in 1958 at the Patuxent Wildlife Research Center, Bureau of Sport Fisheries and Wildlife Laurel, Maryland. Early field trials by personnel of the Division of Wildlife Services and the Denver Wildlife Research Center indicated that ground-application techniques had promise but limitations of the equipment precluded successful large-scale roost treatments. In 1966, Patuxent Center personnel began using tanker-type aircraft to evaluate high-volume aerial applications of wetting agents. The success of these tests led to the use of small aircraft to make low-volume, high-concentration aerial applications just prior to expected rainfall. Recent trials of the low-volume method show that, with some limitations, it is effective, inexpensive, and safe to the environment. Current research emphasizes the screening of new candidate materials for efficacy, biodegradability, and toxicity to plants and non-target animals, as well as basic investigations of the avian physiological mechanisms involved. Field trials to develop more effective application techniques will continue.

  11. Electric power market agent design

    Science.gov (United States)

    Oh, Hyungseon

    The electric power industry in many countries has been restructured in the hope of a more economically efficient system. In the restructured system, traditional operating and planning tools based on true marginal cost do not perform well since information required is strictly confidential. For developing a new tool, it is necessary to understand offer behavior. The main objective of this study is to create a new tool for power system planning. For the purpose, this dissertation develops models for a market and market participants. A new model is developed in this work for explaining a supply-side offer curve, and several variables are introduced to characterize the curve. Demand is estimated using a neural network, and a numerical optimization process is used to determine the values of the variables that maximize the profit of the agent. The amount of data required for the optimization is chosen with the aid of nonlinear dynamics. To suggest an optimal demand-side bidding function, two optimization problems are constructed and solved for maximizing consumer satisfaction based on the properties of two different types of demands: price-based demand and must-be-served demand. Several different simulations are performed to test how an agent reacts in various situations. The offer behavior depends on locational benefit as well as the offer strategies of competitors.

  12. Cooperative planning in multi-agent systems

    OpenAIRE

    Torreño Lerma, Alejandro

    2016-01-01

    [EN] Automated planning is a centralized process in which a single planning entity, or agent, synthesizes a course of action, or plan, that satisfies a desired set of goals from an initial situation. A Multi-Agent System (MAS) is a distributed system where a group of autonomous agents pursue their own goals in a reactive, proactive and social way. Multi-Agent Planning (MAP) is a novel research field that emerges as the integration of automated planning in MAS. Agents are endowed with plan...

  13. Anchor Toolkit - a secure mobile agent system

    Energy Technology Data Exchange (ETDEWEB)

    Mudumbai, Srilekha S.; Johnston, William; Essiari, Abdelilah

    1999-05-19

    Mobile agent technology facilitates intelligent operation insoftware systems with less human interaction. Major challenge todeployment of mobile agents include secure transmission of agents andpreventing unauthorized access to resources between interacting systems,as either hosts, or agents, or both can act maliciously. The Anchortoolkit, designed by LBNL, handles the transmission and secure managementof mobile agents in a heterogeneous distributed computing environment. Itprovides users with the option of incorporating their security managers.This paper concentrates on the architecture, features, access control anddeployment of Anchor toolkit. Application of this toolkit in a securedistributed CVS environment is discussed as a case study.

  14. An Agent-Based Distributed Manufacturing System

    Institute of Scientific and Technical Information of China (English)

    J.Li; J.Y.H.Fuh; Y.F.Zhang; A.Y.C.Nee

    2006-01-01

    Agent theories have shown their promising capability in solving distributed complex system ever since its development. In this paper, one multi-agent based distributed product design and manufacturing planning system is presented. The objective of the research is to develop a distributed collaborative design environment for supporting cooperation among the existing engineering functions. In the system, the functional agents for design, manufacturability evaluation,process planning and scheduling are efficiently integrated with a facilitator agent. This paper firstly gives an introduction to the system structure, and the definitions for each executive agent are then described and a prototype of the proposed is also included at the end part.

  15. Selected Problems on Mobile Agent Communication

    OpenAIRE

    Yinka A. Adekunle; Sola S. Maitanmi

    2011-01-01

    Mobile agent technology offers a new computing paradigm in which a program, in the form of a software agent, can transfer its execution from agent to agent masquerading itself as the original source of message. The use of mobile code has a long history dating back to the use of remote job entry systems in the 1960's. Today's agent incarnations can be characterized in a number of ways ranging from simple distributed objects to highly secured software with algorithm that can only be interpreted...

  16. Reversal agents in anaesthesia and critical care

    Directory of Open Access Journals (Sweden)

    Nibedita Pani

    2015-01-01

    Full Text Available Despite the advent of short and ultra-short acting drugs, an in-depth knowledge of the reversal agents used is a necessity for any anaesthesiologist. Reversal agents are defined as any drug used to reverse the effects of anaesthetics, narcotics or potentially toxic agents. The controversy on the routine reversal of neuromuscular blockade still exists. The advent of newer reversal agents like sugammadex have made the use of steroidal neuromuscular blockers like rocuronium feasible in rapid sequence induction situations. We made a review of the older reversal agents and those still under investigation for drugs that are regularly used in our anaesthesia practice.

  17. In vitro and in vivo evaluation of poly(L-lactide-co glycolide)( PLGA) micro bubbles as a contrast agent

    International Nuclear Information System (INIS)

    To achieve reliable and reproducible myocardial opacification after intravenous administration of echocardiographic contrast agents, this study was performed to fabricate a kind of poly(L-lactide-co-glycolide) (PLGA) micro bubbles-based contrast agent with a modified double emulsion method which incorporates and later sublimes po rogen, leaving voids capable of being filled with gas in their places. The morphology and size distribution of the micro bubbles were investigated. The porous inner structure formed in the micro bubble contrast agents were further proved by con focal laser scanning microscope (CLSM). All the results satisfied the requirements of ideal contrast agents. Acoustic measurement set-up detected the excellent scatter ability of the PLGA (70/30) micro bubbles. It demonstrated this kind of polymer-shell contrast agents could achieve efficient left ventricular opacification and the improved delineation of left ventricular endocardial borders. Especially the safe and successful myocardial opacification in close-chest dogs were observed

  18. 75 FR 56489 - Separation Distances of Ammonium Nitrate and Blasting Agents From Explosives or Blasting Agents...

    Science.gov (United States)

    2010-09-16

    ... Ammonium Nitrate and Blasting Agents From Explosives or Blasting Agents (2002R-226P) AGENCY: Bureau of... CFR 555.220 set forth a table of separation distances of ammonium nitrate and blasting agents from explosives or blasting agents followed by six explanatory notes. Note three (3) states that the...

  19. Intelligent agent support for automated radiology exam

    Science.gov (United States)

    Shang, Yi; Popescu, Mihail

    2000-10-01

    A difficult problem in automatic medical image understanding is that for every image type such as x-ray and every body organ such as heart, there exist specific solutions that do not allow for generalization. Just collecting all the specific solutions will not achieve the vision of a computerized physician. To address this problem, we propose an intelligent agent approach that is based on agent-oriented programming is that it combines the benefits of object-oriented programming and expert system. For radiology image understanding, we present a multi- agent system that is composed of two major types of intelligent agents: radiologist agents and patient agents. A patient agent asks for multiple opinions from radiologists agents in interpreting a given set of images and then integrates the opinions. A radiologist agent decomposes the image recognition task into smaller problems that are solved collectively by multiple intelligent sub-agents. Finally, we present a preliminary implementation and running examples of the multi-agent system.

  20. A SURVEY OF THE PROPERTIES OF AGENTS

    Directory of Open Access Journals (Sweden)

    Kornelije Rabuzin

    2006-06-01

    Full Text Available In the past decade agent systems were considered to be as one of the major fields of study in Artificial Intelligence (AI field. Many different definitions of agents were presented and several different approaches describing agency can be distinguished. While some authors have tried to define “what” an agent really is, others have tried to identify agents by means of properties which they should possess. Most authors agree on these properties (at least basic set of properties which are intrinsic to agents. Since agent's definitions are not consistent, we are going to give an overview and list the properties intrinsic to an agent. Many different adjectives were attached to the term agent as well and many different kinds of agents and different architectures emerged too. The aim of this paper it go give an overview of what was going on in the field while taking into consideration main streams and projects. We will also present some guidelines important when modelling agent systems and say something about security issues. Also, some existing problems which restrict the wider usage of agents will be mentioned too.

  1. Agent-Based Modeling and Mapping of Manufacturing System

    Institute of Scientific and Technical Information of China (English)

    Z; Zhang

    2002-01-01

    Considering the agent-based modeling and mapping i n manufacturing system, some system models are described in this paper, which are included: Domain Based Hierarchical Structure (DBHS), Cascading Agent Structure (CAS), Proximity Relation Structure (PRS), and Bus-based Network Structure (BNS ). In DBHS, one sort of agents, called static agents, individually acts as Domai n Agents, Resources Agents, UserInterface Agents and Gateway Agents. And the oth ers, named mobile agents, are the brokers of task and ...

  2. Mobile agents for distributed decision support systems

    Directory of Open Access Journals (Sweden)

    Blaz Rodič

    2011-03-01

    Full Text Available This article focuses on the performance of Java based mobile agents using format translation via an intermediary XML based format. Our goal was to develop and verify the performance of a lightweight, mobile agent based solution that would allow strong security, portability and access to heterogeneous data resources from a mobile platform to facilitate exchange of data between simulation models and data resources. We have developed two types of agents: a mobile agent that functions as a server for queries in SQL and converts the query results into XML documents and a stationary agent acting as a client for query forwarding and conversion of received documents into text files readable by a client application. We have tested the performance of the agents in a distributed simulation scenario and established that the agents can be used to connect heterogeneous simulation models and other applications, improving their connectivity and usability.

  3. Agent-Oriented Probabilistic Logic Programming

    Institute of Scientific and Technical Information of China (English)

    Jie Wang; Shi-Er Ju; Chun-Nian Liu

    2006-01-01

    Currently, agent-based computing is an active research area, and great efforts have been made towards the agent-oriented programming both from a theoretical and practical view. However, most of them assume that there is no uncertainty in agents' mental state and their environment. In other words, under this assumption agent developers are just allowed to specify how his agent acts when the agent is 100% sure about what is true/false. In this paper, this unrealistic assumption is removed and a new agent-oriented probabilistic logic programming language is proposed, which can deal with uncertain information about the world. The programming language is based on a combination of features of probabilistic logic programming and imperative programming.

  4. Knowledge Management in Role Based Agents

    Science.gov (United States)

    Kır, Hüseyin; Ekinci, Erdem Eser; Dikenelli, Oguz

    In multi-agent system literature, the role concept is getting increasingly researched to provide an abstraction to scope beliefs, norms, goals of agents and to shape relationships of the agents in the organization. In this research, we propose a knowledgebase architecture to increase applicability of roles in MAS domain by drawing inspiration from the self concept in the role theory of sociology. The proposed knowledgebase architecture has granulated structure that is dynamically organized according to the agent's identification in a social environment. Thanks to this dynamic structure, agents are enabled to work on consistent knowledge in spite of inevitable conflicts between roles and the agent. The knowledgebase architecture is also implemented and incorporated into the SEAGENT multi-agent system development framework.

  5. An Agent Framework of Tourism Recommender System

    Directory of Open Access Journals (Sweden)

    Jia Zhi Yang

    2016-01-01

    Full Text Available This paper proposes the development of an Agent framework for tourism recommender system. The recommender system can be featured as an online web application which is capable of generating a personalized list of preference attractions for tourists. Traditional technologies of classical recommender system application domains, such as collaborative filtering, content-based filtering and content-based filtering are effectively adopted in the framework. In the framework they are constructed as Agents that can generate recommendations respectively. Recommender Agent can generate recommender information by integrating the recommendations of Content-based Agent, collaborative filtering-based Agent and constraint-based Agent. In order to make the performance more effective, linear combination method of data fusion is applied. User interface is provided by the tourist Agent in form of webpages and mobile app.

  6. Morphological Decomposition in Reading Hebrew Homographs

    Science.gov (United States)

    Miller, Paul; Liran-Hazan, Batel; Vaknin, Vered

    2016-01-01

    The present work investigates whether and how morphological decomposition processes bias the reading of Hebrew heterophonic homographs, i.e., unique orthographic patterns that are associated with two separate phonological, semantic entities depicted by means of two morphological structures (linear and nonlinear). In order to reveal the nature of…

  7. Arabic Morphology in the Neural Language System

    Science.gov (United States)

    Boudelaa, Sami; Pulvermuller, Friedemann; Hauk, Olaf; Shtyrov, Yury; Marslen-Wilson, William

    2010-01-01

    There are two views about morphology, the aspect of language concerned with the internal structure of words. One view holds that morphology is a domain of knowledge with a specific type of neurocognitive representation supported by specific brain mechanisms lateralized to left fronto-temporal cortex. The alternate view characterizes morphological…

  8. Lexical Morphology: Structure, Process, and Development

    Science.gov (United States)

    Jarmulowicz, Linda; Taran, Valentina L.

    2013-01-01

    Recent work has demonstrated the importance of derivational morphology to later language development and has led to a consensus that derivation is a lexical process. In this review, derivational morphology is discussed in terms of lexical representation models from both linguistic and psycholinguistic perspectives. Input characteristics, including…

  9. Automatic Target Detection by Optimal Morphological Filters

    Institute of Scientific and Technical Information of China (English)

    YU Nong(余农); WU Hao(吴昊); WU ChangYong(吴常泳); LI YuShu(李予蜀)

    2003-01-01

    It is widely accepted that the design of morphological filters, which are optimal in some sense, is a difficult task. In this paper a novel method for optimal learning of morphological filtering parameters (Genetic training algorithm for morphological filters, GTAMF) is presented.GTAMF adopts new crossover and mutation operators called the curved cylinder crossover and master-slave mutation to achieve optimal filtering parameters in a global searching. Experimental results show that this method is practical, easy to extend, and markedly improves the performances of morphological filters. The operation of a morphological filter can be divided into two basic problems including morphological operation and structuring element (SE) selection. The rules for morphological operations are predefined so that the filter's properties depend merely on the selection of SE. By means of adaptive optimization training, structuring elements possess the shape and structural characteristics of image targets, and give specific information to SE. Morphological filters formed in this way become certainly intelligent and can provide good filtering results and robust adaptability to image targets with clutter background.

  10. Morphological Typology of Languages for IR.

    Science.gov (United States)

    Pirkola, Ari

    2001-01-01

    Presents a morphological classification of languages from the information retrieval (IR) perspective. Discusses differences in inflection, derivation, and compounding; index of synthesis and index of fusion; cross-language retrieval research; the need for semantic and syntactic typologies; and the effects of morphology and stemming in IR.…

  11. Morphology of solidification front in eutectic

    Directory of Open Access Journals (Sweden)

    M. Trepczyńska - Łent

    2009-07-01

    Full Text Available In this paper the analysis of morphology of solidification front in eutectic made. It was present influence of composition, solidification velocity, concentration micro-field and capillarity effects on the morphology of the solid/liquid interface. It was introduced phase-field model.

  12. Morphology of solidification front in eutectic

    OpenAIRE

    M. Trepczyńska - Łent; T. Giętka; T. Szykowny

    2009-01-01

    In this paper the analysis of morphology of solidification front in eutectic made. It was present influence of composition, solidification velocity, concentration micro-field and capillarity effects on the morphology of the solid/liquid interface. It was introduced phase-field model.

  13. MR urography for morphological and functional assessment of UT abnormalities

    International Nuclear Information System (INIS)

    Full text: Introduction: Magnetic resonance urography is a new, modern method in various urological conditions. The method is most often used for the evaluation of hydronephrosis and provides valuable information on a variety of obstructive uropathy, presenting both morphological and functional information about the urinary tract. What you will learn: The purpose of this presentation is to examine the current role of MR urography in evaluation of hydronephrosis and hydroureter, variants and congenital anomalies of the kidney, various causes of obstruction, tumor and inflammation, hematuria. Combining static and dynamic MR urography, yielding both morphological and functional information by using different sequences with and without the injection of contrast agents. Highlighted the advantages of the method in children and demonstrated software programs available for postprocessing in urodiagnostic illustrated with typical clinical cases. Discussion: MR urography is a promising method to diagnose a wide range of pathological conditions of the urogenital tract, with huge development opportunities in urogenital tract imaging. It integrates excellent anatomical informative in combination with various functional data in the absence of ionizing radiation. Postprocessing algorithms facilitate the assessment of differentiated renal function, by generating curves of signal intensity - time. Due to the risk of nephrogenic systemic fibrosis, using the contrast media requires caution, especially in cases of impaired renal function. Conclusion: MR urography is a highly informative method in the case of diagnostic difficulties using conventional techniques, overcoming their limitations and has the potential to become a future the leading method for diagnosing kidney disease, especially in infants and children

  14. Mechanical and morphological characterization of polypropylene toughened with olefinic elastomer

    Directory of Open Access Journals (Sweden)

    Lotti Cybele

    2000-01-01

    Full Text Available The effect of incorporating (C2-C8 ethylene-octene elastomer on the mechanical properties and morphology of polypropylene copolymers has been investigated employing two types of PP copolymer, with and without nucleating agent. The results were compared to the ones presented by a commercial PP heterophase (reactor impact modified PP/EPR. The addition of the elastomer increases the toughness of the blends but reduces their stiffness. PP blends in the low elastomer content region (< 20% show low values of the Izod impact strength and both, elastomer content and impact strength, are directly proportional to the area under the beta damping peak or its maximum intensity of the elastomer. The morphology is a continuous pattern of segregate elastomeric particles with average particle size in the range of 0.27 mum to 0.39 mum. The average particle size and particle size distribution plotted in log-normal distribution curves, increases slightly with the increase in the elastomer content. The reactor modified PP heterophase has a broader particle size distribution and an average particle size of 0.56 mum, at the lower limit but inside the range for good impact performance, as observed.

  15. 10th International Conference on Practical Applications of Agents and Multi-Agent Systems

    CERN Document Server

    Pérez, Javier; Golinska, Paulina; Giroux, Sylvain; Corchuelo, Rafael; Trends in Practical Applications of Agents and Multiagent Systems

    2012-01-01

    PAAMS, the International Conference on Practical Applications of Agents and Multi-Agent Systems is an evolution of the International Workshop on Practical Applications of Agents and Multi-Agent Systems. PAAMS is an international yearly tribune to present, to discuss, and to disseminate the latest developments and the most important outcomes related to real-world applications. It provides a unique opportunity to bring multi-disciplinary experts, academics and practitioners together to exchange their experience in the development of Agents and Multi-Agent Systems.   This volume presents the papers that have been accepted for the 2012 in the workshops: Workshop on Agents for Ambient Assisted Living, Workshop on Agent-Based Solutions for Manufacturing and Supply Chain and Workshop on Agents and Multi-agent systems for Enterprise Integration.

  16. Infectious endocarditis caused by Nocardia sp.: histological morphology as a guide for the specific diagnosis

    Directory of Open Access Journals (Sweden)

    Jussara Bianchi Castelli

    2011-08-01

    Full Text Available Nocardia is a rare opportunistic agent, which may affect immunocompromised individuals causing lung infections and exceptionally infective endocarditis (IE. There are few reports of IE caused by Nocardia sp., usually involving biological prostheses but rarely in natural valves. Its accurate microbiological identification may be hampered by the similarity with Rhodococcus equi and Corynebacterium spp. Here we report a case of native mitral valve IE caused by this agent in which the clinical absence of response to vancomycin and the suggestion of Nocardia sp. by histology pointed to the misdiagnosis of Corynebacterium spp. in blood cultures. The histological morphology can advise on the need for expansion of cultivation time and use of extra microbiological procedures that lead to the differential diagnosis with Corynebacterium spp. and other agents, which is essential to establish timely specific treatment, especially in immunocompromised patients.

  17. The Contribution of Morphological Awareness to the Spelling of Morphemes and Morphologically Complex Words in French

    Science.gov (United States)

    Fejzo, Anila

    2016-01-01

    The goal of this study was to explore the relationship between morphological awareness and the spelling of morphemes and morphologically complex words among 75 third- and fourth-grade Francophone students of low socio-economic status. To reach this objective, we administered a dictation comprised of morphologically complex words with prefixes,…

  18. Galaxy morphology - an unsupervised machine learning approach

    CERN Document Server

    Schutter, Andrew

    2015-01-01

    Structural properties posses valuable information about the formation and evolution of galaxies, and are important for understanding the past, present, and future universe. Here we use unsupervised machine learning methodology to analyze a network of similarities between galaxy morphological types, and automatically deduce a morphological sequence of galaxies. Application of the method to the EFIGI catalog show that the morphological scheme produced by the algorithm is largely in agreement with the De Vaucouleurs system, demonstrating the ability of computer vision and machine learning methods to automatically profile galaxy morphological sequences. The unsupervised analysis method is based on comprehensive computer vision techniques that compute the visual similarities between the different morphological types. Rather than relying on human cognition, the proposed system deduces the similarities between sets of galaxy images in an automatic manner, and is therefore not limited by the number of galaxies being ...

  19. SDSS superclusters: morphology and galaxy content

    CERN Document Server

    Einasto, M; Tempel, E; Gramann, M; Liivamagi, L J; Einasto, J

    2014-01-01

    We compare the galaxy populations in superclusters of different morphology in the nearby Universe (180 < d < 270 Mpc) to see whether the inner structure and overall morphology of superclusters are important in shaping galaxy properties in superclusters. Supercluster morphology has been found with Minkowski functionals. We analyse the probability density distributions of colours, morphological types, stellar masses, star formation rates (SFR) of galaxies, and the peculiar velocities of the main galaxies in groups in superclusters of filament and spider types, and in the field. We show that the fraction of red, early-type, low SFR galaxies in filament-type superclusters is higher than in spider-type superclusters; in low-density global environments their fraction is lower than in superclusters. In all environments the fraction of red, high stellar mass, and low SFR galaxies in rich groups is higher than in poor groups. In superclusters of spider morphology red, high SFR galaxies have higher stellar masses...

  20. PECULIARITIES OF MORPHOLOGICAL VERIFICATION IN BREAST CANCER

    Directory of Open Access Journals (Sweden)

    L.F. Zhandarova

    2008-06-01

    Full Text Available 80 case histories of patients with breast cancer were analyzed. During the preoperative examination with objective and instrumental examination methods used the malignant process was suspected but no morphological verification was received. Physical examination revealed 75% cases of cancer. Roentgenologic evidence of malignant tumor was found in 43.5% women. Ultrasound examination of mammary glands showed that 57.7% of patients had cancer symptoms. Despite the repeated puncture aspiration biopsy, preoperative morphological examination proved to be negative. The reasons of morphological verification failure are connected with technical difficulties and morphological features of tumor structure. Negative malignant process verification necessitated the diagnostic partial mastectomy. To achieve ablasticity ofexcisional biopsyit is necessary to keep 2 cm from the tumor. Staged morphological diagnosis verifies the diagnosis in all patients, allowing to choose the adequate extentof surgical procedures.

  1. Morphological and molecular convergences in mammalian phylogenetics.

    Science.gov (United States)

    Zou, Zhengting; Zhang, Jianzhi

    2016-01-01

    Phylogenetic trees reconstructed from molecular sequences are often considered more reliable than those reconstructed from morphological characters, in part because convergent evolution, which confounds phylogenetic reconstruction, is believed to be rarer for molecular sequences than for morphologies. However, neither the validity of this belief nor its underlying cause is known. Here comparing thousands of characters of each type that have been used for inferring the phylogeny of mammals, we find that on average morphological characters indeed experience much more convergences than amino acid sites, but this disparity is explained by fewer states per character rather than an intrinsically higher susceptibility to convergence for morphologies than sequences. We show by computer simulation and actual data analysis that a simple method for identifying and removing convergence-prone characters improves phylogenetic accuracy, potentially enabling, when necessary, the inclusion of morphologies and hence fossils for reliable tree inference. PMID:27585543

  2. Extraction and Study of Bacteriophages, Used against Agents of Potato Soft Rot

    OpenAIRE

    Magda D. Davitashvili; Lela Z. Tsiklauri

    2012-01-01

    The use of specific bacteriophages and their complex mixtures against bacterial diseases is very effective. As for causative agent of potato soft rot Erwinia carotovora, specific phages (25 phages in total) were extracted from diseased potato, soil and sewage. The study of their biological properties showed the diversity of phages in terms of lytic action, virion plaque and morphology, as well as in relation to different environmental factors. Phages showed explicit antibacterial activity in ...

  3. Fusarium oxysporum as causal agent of tomato wilt and fruit rot

    OpenAIRE

    Maja Ignjatov; Dragana Milošević; Zorica Nikolić; Jelica Gvozdanović-Varga; Dušica Jovičić; Gordana Zdjelar

    2012-01-01

    Tomatoes are parasitized by a number of pathogens, including Fusarium oxysporum f. sp. lycopersici, causal agent of fusarium wilt. Fresh vegetable fruits can be contaminated with various fungi that produce mycotoxins, which is an important issue for human health. The objective of this paper was to isolate, determine, and identify causal organisms of tomato wilt and fruit rot, based on the pathogens morphological and molecular characteristics. Samples of dis...

  4. Interaction Protocols in Multi-Agent Systems based on Agent Petri Nets Model

    Directory of Open Access Journals (Sweden)

    Kamel Barkaoui

    2013-08-01

    Full Text Available This paper deals with the modeling of interaction between agents in Multi Agents System (MAS based on Agent Petri Nets (APN. Our models are created based on communicating agents. Indeed, an agent initiating a conversation with other can specify the interaction protocol wishes to follow. The combination of APN and FIPA Protocols schemes leads to a set of deployment formal rules for points where model interaction can be successfully implemented. We introduce some models FIPA standard protocols.

  5. Fault Tolerance Mobile Agent System Using Witness Agent in 2-Dimensional Mesh Network

    Directory of Open Access Journals (Sweden)

    Ahmad Rostami

    2010-09-01

    Full Text Available Mobile agents are computer programs that act autonomously on behalf of a user or its owner and travel through a network of heterogeneous machines. Fault tolerance is important in their itinerary. In this paper, existent methods of fault tolerance in mobile agents are described which they are considered in linear network topology. In the methods three agents are used to fault tolerance by cooperating to each others for detecting and recovering server and agent failure. Three types of agents are: actual agent which performs programs for its owner, witness agent which monitors the actual agent and the witness agent after itself, probe which is sent for recovery the actual agent or the witness agent on the side of the witness agent. Communication mechanism in the methods is message passing between these agents. The methods are considered in linear network. We introduce our witness agent approach for fault tolerance mobile agent systems in Two Dimensional Mesh (2D-Mesh Network. Indeed Our approach minimizes Witness-Dependency in this network and then represents its algorithm.

  6. Morphology of technological levels in an innovation propagation model.

    Science.gov (United States)

    Kim, Yup; Han, Bumhee; Yook, Soon-Hyung

    2010-10-01

    We study the dynamical properties of the propagation of innovation on a two-dimensional lattice, random network, scale-free network, and Cayley tree. In order to investigate the diversity of technological level, we study the scaling property of width, W(N,t), which represents the root mean square of the technological level of agents. Here, N is the total number of agents. From the numerical simulations, we find that the steady-state value of W(N,t), W(sat)(N), scales as W(sat)(N) ∼ N(-1/2) when the system is in a flat ordered phase for d ≥ 2. In the flat ordered phase, most of the agents have the same technological level. On the other hand, when the system is in a smooth disordered phase, the value of W(sat)(N) does not depend on N. These behaviors are completely different from those observed on a one-dimensional (1D) lattice. By considering the effect of the underlying topology on the propagation dynamics for d ≥ 2, we also provide a mean-field analysis for W(sat)(N), which agrees very well with the observed behaviors of W(sat)(N). This directly shows that the morphological properties in order-disorder transition on a 1D lattice is completely different from that on higher dimensions. It also provides an evidence that the upper critical dimension for the roughening transition of the propagation of innovation is d(u)=2. PMID:21230348

  7. Agent Based Individual Traffic guidance

    DEFF Research Database (Denmark)

    Wanscher, Jørgen Bundgaard

    2004-01-01

    vehicle can be obtained through cellular phone tracking or GPS systems. This information can then be used to provide individual traffic guidance as opposed to the mass information systems of today -- dynamic roadsigns and trafficradio. The goal is to achieve better usage of road and time. The main topic......When working with traffic planning or guidance it is common practice to view the vehicles as a combined mass. >From this models are employed to specify the vehicle supply and demand for each region. As the models are complex and the calculations are equally demanding the regions and the detail of...... the road network is aggregated. As a result the calculations reveal only what the mass of vehicles are doing and not what a single vehicle is doing. This is the crucial difference to ABIT (Agent Based Individual Trafficguidance). ABIT is based on the fact that information on the destination of each...

  8. Bioprotective agents in safety control

    Directory of Open Access Journals (Sweden)

    Dimitrijević-Branković Suzana I.

    2003-01-01

    Full Text Available Food poisoning is the one of the main health hazards even today. More than 200 known diseases are transmitted through food. The causes of foodborne illness include viruses, bacteria, parasites, toxins, metals, and prions and the symptoms of foodborne illness range from mild gastroenteritis to life-threatening neurological, hepatic and renal syndromes.The prevention of food poisonings represents very serious task for food manufacturers. Beside food control according to the concept "from the farm to the table" there is increased need for the development of new technology for longer shelf lifes of food. Food fermented by lactic acid bacteria (LAB and traditionally considered to be safe. There are many substances produced by LAB that affect the shelf life of fermented food, by active suppression of poisoning microorganisms growth. Because of that, the LAB is recently considered as bioprotective agents that have important role in food safety.

  9. [Anticonvulsant agents in neuralgic pain.].

    Science.gov (United States)

    Jurna, I; Zenz, M

    1992-06-01

    The anticonvulsants, carbamazepine, clonazepam, phenytoin, and valproic acid are capable of depressing attacks of shooting pain in neuralgia. Shooting pain is perceived in trigeminal, intercostal, and other neuralgias, as a consequence of infectious diseases such as herpes zoster, and in the course of polyneuropathies of various causes. It is due to injury of nociceptive afferents, which generate bursts of activity in response to appropriate environmental changes. The anticonvulsant agents have no analgesic property per se, so that background pain remains unchanged. The depression of shooting pain results from the anticonvulsant action of the compounds. Both carbamazepine and phenytoin block synaptic transmission of neuronal hyperactivity by a direct depressant action that includes reduction of sodium conductance and by activation of inhibitory control. Clonazepam and valproic acid act by enhancing GABA-mediated inhibition of synaptic transmission. Carbamazepine is by far the most widely used compound; phenytoin, clonazepam, and valproic acid are not so popular because of their side effects. PMID:18415623

  10. Host modulation by therapeutic agents

    Directory of Open Access Journals (Sweden)

    Sugumari Elavarasu

    2012-01-01

    Full Text Available Periodontal disease susceptible group present advanced periodontal breakdown even though they achieve a high standard of oral hygiene. Various destructive enzymes and inflammatory mediators are involved in destruction. These are elevated in case of periodontal destruction. Host modulation aims at bringing these enzymes and mediators to normal level. Doxycycline, nonsteroidal anti-inflammatory drugs (NSAIDs, bisphosphonates, nitrous oxide (NO synthase inhibitors, recombinant human interleukin-11 (rhIL-11, omega-3 fatty acid, mouse anti-human interleukin-6 receptor antibody (MRA, mitogen-activated protein kinase (MAPK inhibitors, nuclear factor-kappa B (NF-kb inhibitors, osteoprotegerin, and tumor necrosis factor antagonist (TNF-α are some of the therapeutic agents that have host modulation properties.

  11. Kinetically controlled synthesis of large-scale morphology-tailored silver nanostructures at low temperature

    Science.gov (United States)

    Zhang, Ling; Zhao, Yuda; Lin, Ziyuan; Gu, Fangyuan; Lau, Shu Ping; Li, Li; Chai, Yang

    2015-08-01

    Ag nanostructures are widely used in catalysis, energy conversion and chemical sensing. Morphology-tailored synthesis of Ag nanostructures is critical to tune physical and chemical properties. In this study, we develop a method for synthesizing the morphology-tailored Ag nanostructures in aqueous solution at a low temperature (45 °C). With the use of AgCl nanoparticles as the precursor, the growth kinetics of Ag nanostructures can be tuned with the pH value of solution and the concentration of Pd cubes which catalyze the reaction. Ascorbic acid and cetylpyridinium chloride are used as the mild reducing agent and capping agent in aqueous solution, respectively. High-yield Ag nanocubes, nanowires, right triangular bipyramids/cubes with twinned boundaries, and decahedra are successfully produced. Our method opens up a new environmentally-friendly and economical route to synthesize large-scale and morphology-tailored Ag nanostructures, which is significant to the controllable fabrication of Ag nanostructures and fundamental understanding of the growth kinetics.Ag nanostructures are widely used in catalysis, energy conversion and chemical sensing. Morphology-tailored synthesis of Ag nanostructures is critical to tune physical and chemical properties. In this study, we develop a method for synthesizing the morphology-tailored Ag nanostructures in aqueous solution at a low temperature (45 °C). With the use of AgCl nanoparticles as the precursor, the growth kinetics of Ag nanostructures can be tuned with the pH value of solution and the concentration of Pd cubes which catalyze the reaction. Ascorbic acid and cetylpyridinium chloride are used as the mild reducing agent and capping agent in aqueous solution, respectively. High-yield Ag nanocubes, nanowires, right triangular bipyramids/cubes with twinned boundaries, and decahedra are successfully produced. Our method opens up a new environmentally-friendly and economical route to synthesize large-scale and morphology

  12. Ultrasound imaging of breast tumor perfusion and neovascular morphology.

    Science.gov (United States)

    Hoyt, Kenneth; Umphrey, Heidi; Lockhart, Mark; Robbin, Michelle; Forero-Torres, Andres

    2015-09-01

    A novel image processing strategy is detailed for simultaneous measurement of tumor perfusion and neovascular morphology parameters from a sequence of dynamic contrast-enhanced ultrasound (DCE-US) images. After normalization and tumor segmentation, a global time-intensity curve describing contrast agent flow was analyzed to derive surrogate measures of tumor perfusion (i.e., peak intensity, time-to-peak intensity, area under the curve, wash-in rate, wash-out rate). A maximum intensity image was generated from these same segmented image sequences, and each vascular component was skeletonized via a thinning algorithm. This skeletonized data set and collection of vessel segments were then investigated to extract parameters related to the neovascular network and physical architecture (i.e., vessel-to-tissue ratio, number of bifurcations, vessel count, average vessel length and tortuosity). An efficient computation of local perfusion parameters was also introduced and operated by averaging time-intensity curve data over each individual neovascular segment. Each skeletonized neovascular segment was then color-coded by these local measures to produce a parametric map detailing spatial properties of tumor perfusion. Longitudinal DCE-US image data sets were collected in six patients diagnosed with invasive breast cancer using a Philips iU22 ultrasound system equipped with a L9-3 transducer and Definity contrast agent. Patients were imaged using US before and after contrast agent dosing at baseline and again at weeks 6, 12, 18 and 24 after treatment started. Preliminary clinical results suggested that breast tumor response to neoadjuvant chemotherapy may be associated with temporal and spatial changes in DCE-US-derived parametric measures of tumor perfusion. Moreover, changes in neovascular morphology parametric measures may also help identify any breast tumor response (or lack thereof) to systemic treatment. Breast cancer management from early detection to therapeutic

  13. Concretion morphology, classification and genesis

    Science.gov (United States)

    Sellés-Martínez, J.

    1996-11-01

    A discussion of the most relevant morphological features of concretionary bodies and the different classifications, and the criteria involved in these classifications is presented, together with suggestions for improvements to the various classification schemes. The meaning of syngenetic, diagenetic and epigenetic related to the relative timing and environment of growth of concretionary bodies is also reviewed and discussed. The replacement of mixed morphogenetic classifications, which lead to conflicting results, by classification categories based on textural features is proposed. Because the identification of the genetic environment of a concretionary body tells little about its history, I recommend defining growth patterns in which the successive steps associated with changes in composition and/or texture and the development of new structures are recorded. A new path is presented that accounts for the contradiction between textural and isotope features, which suggests respectively syngenetic and diagenetic (or even epigenetic) signatures. This new path is characterized by the preservation of large porosities over very long time spans and down to depths that are somewhat greater than expected, due to the inhibition of normal compaction caused by early overpressuring. This overpressuring is the result of the development of hydraulic seals since approximately the syngenetic phase times. The concepts of "force of crystallization" and "displacive growth" are also reviewed. It is being suggested to discard some controversial interpretations of their actual importance for true concretionary displacive growth under epigenetic conditions. In accordance with other authors, the conclusion is reached that displacive growth is only possible if the shear strength of the host is very low and the stress field within the host is almost hydrostatic. A new model (the Symcompactional Concretionary Growth Model) is proposed which explains how a concretionary body, generally a nodule

  14. Studies of waterborne agents of viral gastroenteritis. Final report Feb 79-Feb 81

    Energy Technology Data Exchange (ETDEWEB)

    Dolin, R.

    1983-07-01

    The etiologic agent of a large outbreak of waterborne viral gastroenteritis was detected employing immune electron microscopy (IEM) and a newly developed solid phase radioimmunoassay (RIA). This agent, referred to as the Snow Mountain Agent (SMA), is 27-32 nm. in diameter, has cubic symmetry, and is morphologically similar to, but antigentically distinct from the previously described Norwalk and Hawaii agents. After an incubation period of 18 to 48 hours, the agent is shed in stools of acutely ill individuals for a period of one to five days. Employing both IEM and RIA, serum antibody rises were observed in 3/3 naturally occurring cases and in 8/9 cases of experimentally-induced illness in normal volunteers (the studies in normal volunteers had been carried out prior to the initiation of studies supported by this grant). IEM and RIA appeared to be equally sensitive for detection of antibody rises, but the RIA was more sensitive than IEM for the detection of SMA in stool specimens. Preliminary attempts to cultivate the agent in vitro were unsuccessful.

  15. Context-aware modeling of neuronal morphologies

    Directory of Open Access Journals (Sweden)

    Benjamin eTorben-Nielsen

    2014-09-01

    Full Text Available Neuronal morphologies are pivotal for brain functioning: physical overlap between dendrites and axons constrain the circuit topology, and the precise shape and composition of dendrites determine the integration of inputs to produce an output signal. At the same time, morphologies are highly diverse and variant. The variance, presumably, originates from neurons developing in a densely packed brain substrate where they interact (e.g., repulsion or attraction with other actors in this substrate. However, when studying neurons their context is never part of the analysis and they are treated as if they existed in isolation.Here we argue that to fully understand neuronal morphology and its variance it is important to consider neurons in relation to each other and to other actors in the surrounding brain substrate, i.e., their context. We propose a context-aware computational framework, NeuroMaC, in which large numbers of neurons can be grown simultaneously according to growth rules expressed in terms of interactions between the developing neuron and the surrounding brain substrate.As a proof of principle, we demonstrate that by using NeuroMaC we can generate accurate virtual morphologies of distinct classes both in isolation and as part of neuronal forests. Accuracy is validated against population statistics of experimentally reconstructed morphologies. We show that context-aware generation of neurons can explain characteristics of variation. Indeed, plausible variation is an inherent property of the morphologies generated by context-aware rules. We speculate about the applicability of this framework to investigate morphologies and circuits, to classify healthy and pathological morphologies, and to generate large quantities of morphologies for large-scale modeling.

  16. Evolutionary algorithms and multi-agent systems

    Science.gov (United States)

    Oh, Jae C.

    2006-05-01

    This paper discusses how evolutionary algorithms are related to multi-agent systems and the possibility of military applications using the two disciplines. In particular, we present a game theoretic model for multi-agent resource distribution and allocation where agents in the environment must help each other to survive. Each agent maintains a set of variables representing actual friendship and perceived friendship. The model directly addresses problems in reputation management schemes in multi-agent systems and Peer-to-Peer distributed systems. We present algorithms based on evolutionary game process for maintaining the friendship values as well as a utility equation used in each agent's decision making. For an application problem, we adapted our formal model to the military coalition support problem in peace-keeping missions. Simulation results show that efficient resource allocation and sharing with minimum communication cost is achieved without centralized control.

  17. Diuretic Agents in Treatment of Sudden Deafness

    Institute of Scientific and Technical Information of China (English)

    JI Chang-you; LI Hong-tao; ZHOU Ding-rong; CHEN Ji-chuan; WANG Yi-nan; GUAN Li-qian; ZHANG Min

    2008-01-01

    Objective To study the role of diuretic agents in treating sudden deafness (SD) and explore the possibility of endolymphatic hydrops as a potential cause of SD. Methods Twenty-eight SD cases were reviewed. In 23 cases, treatment was initiated with routine agents. Diuretic agents were later added in 8 of these cases that failed to respond to routine treatment agents. Diuretic agents were included in the initial treatment in the rest 5 cases. In total, 13 cases received diuretics in addition to routine treatment agents and 15 cases received conventional treatment only. Results In the 8 cases who received diuretics after failed conventional treatments, 4 showed hearing improvement, whereas all 5 cases in which diuretics were included in the initial treatment demonstrated hearing improvement. Conclusion These results suggest a possible role of endolymphatic hydrops in the pathophysiologic course of SD. Diuretics should be considered when clear indications exist with no conflicts to other medical conditions.

  18. Myeloproliferative neoplasms: Morphology and clinical practice.

    Science.gov (United States)

    Barbui, Tiziano; Thiele, Jürgen; Vannucchi, Alessandro M; Tefferi, Ayalew

    2016-06-01

    In myeloproliferative neoplasms (MPNs), controversy persists regarding the usefulness and reproducibility of bone marrow (BM) features. Disagreements concerning the WHO classification are mainly focused on the discrimination between essential thrombocythemia (ET) and prefibrotic/early primary myelofibrosis (prePMF) and prodromal polycythemia vera (PV). Criticism mostly refers to lack of standardization of distinctive BM features precluding correct morphological pattern recognition. The distinction between WHO-defined ET and prePMF is not trivial because outcome is significantly worse in prePMF. Morphology was generally considered to be non-specific for the diagnosis of PV. Recent studies have revealed under-diagnosis of morphologically and biologically consistent PV. PMID:26718907

  19. Morphological representation of order-statistics filters.

    Science.gov (United States)

    Charif-Chefchaouni, M; Schonfeld, D

    1995-01-01

    We propose a comprehensive theory for the morphological bounds on order-statistics filters (and their repeated iterations). Conditions are derived for morphological openings and closings to serve as bounds (lower and upper, respectively) on order-statistics filters (and their repeated iterations). Under various assumptions, morphological open-closings and close-openings are also shown to serve as (tighter) bounds (lower and upper, respectively) on iterations of order-statistics filters. Simulations of the application of the results presented to image restoration are finally provided. PMID:18290034

  20. Influence of substrate morphology on Pb growth

    International Nuclear Information System (INIS)

    The crystallographic structure and morphology of Pb layers in their early stage of growth on Si(3 3 5) surface are studied with Reflection High Electron Energy Diffraction (RHEED) and specific resistivity techniques. The vicinal Si(3 3 5), with different surface morphology controlled by the amount of predeposited Au, was used as a substrate. Changes in the substrate morphology, from disordered step distribution through a perfectly ordered Si(3 3 5) to a hill-and-valley structure consisting of wide (1 1 1) terraces and high Miller index facets, cause switching between one- and two-dimensional growth of the Pb structures

  1. Thermal behavior and transformation kinetics of titanium dioxide nanocrystallites prepared by coupling agents

    Energy Technology Data Exchange (ETDEWEB)

    Chen, W.C. [School of Dentistry, Kaohsiung Medical University, 100 Shi-Chuan 1st Road, Kaohsiung 80708, Taiwan (China); Wang, Y.T. [Department of Medical Research and Education, Chen Hsin General Hospital, 45 Cheng-Hsin Street, Pai-Tou, Taipei 11220, Taiwan (China); Shih, C.J., E-mail: cjshih@kmu.edu.t [Department of Fragrance and Cosmetics Science, Kaohsiung Medical University, 100 Shi-Chuan1st Road, Kaohsiung 80708, Taiwan (China)

    2010-02-04

    Coupling agents have been widely used to retard the sintering of silver paste and minimize co-firing defects due to densification mismatch between silver and dielectrics. The thermal-decomposition and crystallization behavior of the coupling agent is a subject of great concern. To elucidate what is responsible for the oxidation, Ti organometallic compounds were calcined at different temperatures (350, 400, 500, 600 {sup o}C) for 2 h and the crystallization behavior was determined by X-ray diffraction (XRD). The activation energy for crystallization of coupling agents was studied by using isothermal methods. According to the quantitative XRD method, the values calculated by the Johnson-Mehi-Avrami equation are 134.9 kJ mol{sup -1}. The growth morphology parameters are 1.061, 0.915, 1.016 respectively. Combining the results of DTA, XRD and TEM, it is found that formation of nanocrystallized titania accompanies the combustion of organometallic compounds.

  2. Thermal behavior and transformation kinetics of titanium dioxide nanocrystallites prepared by coupling agents

    International Nuclear Information System (INIS)

    Coupling agents have been widely used to retard the sintering of silver paste and minimize co-firing defects due to densification mismatch between silver and dielectrics. The thermal-decomposition and crystallization behavior of the coupling agent is a subject of great concern. To elucidate what is responsible for the oxidation, Ti organometallic compounds were calcined at different temperatures (350, 400, 500, 600 oC) for 2 h and the crystallization behavior was determined by X-ray diffraction (XRD). The activation energy for crystallization of coupling agents was studied by using isothermal methods. According to the quantitative XRD method, the values calculated by the Johnson-Mehi-Avrami equation are 134.9 kJ mol-1. The growth morphology parameters are 1.061, 0.915, 1.016 respectively. Combining the results of DTA, XRD and TEM, it is found that formation of nanocrystallized titania accompanies the combustion of organometallic compounds.

  3. Ultrasound contrast agents: bubbles, drops and particles

    OpenAIRE

    Lajoinie, Guillaume Pierre René

    2015-01-01

    The research on the medical use of microbubbles has coontinuously provided fascinating results for half a century. Investigating new agents or new uses of existing agents requires both innovative physics and ideas and extensive testing in-vitro and in vivo. The translation from the lab to the clinic is long and calls upon many specialties. In this dissertation, we have presented and studied various experimental agents for biomedical imaging and therapy, some in the early development phase and...

  4. NESTA: NASA Engineering Shuttle Telemetry Agent

    OpenAIRE

    Semmel, Glenn S.; Davis, Steven R.; Leucht, Kurt W.; Rowe, Dan A.; Smith, Kevin E.; O'Farrel, Ryan l; Boloni, Ladislau

    2006-01-01

    The Electrical Systems Division at the NASA Kennedy Space Center has developed and deployed an agent-based tool to monitor the space shuttle's ground processing telemetry stream. The application, the NASA Engineering Shuttle Telemetry Agent (NESTA), increases situational awareness for system and hardware engineers during ground processing of the shuttle's subsystems. The agent provides autonomous monitoring of the telemetry stream and automatically alerts system engineers when predefined crit...

  5. Intelligent Agents in E-Commerce

    Directory of Open Access Journals (Sweden)

    Valentin LITOIU

    2006-01-01

    Full Text Available This paper emphasizes the importance of intelligent agents in e-commerce, with a particular focus on the B2C and B2B context. From the consumer buying behaviour perspective, agents can be used to assist the following stages: need identification, product brokering, buyer coalition formation, merchant brokering and negotiation. Related to B2B commerce, intelligent agents are involved in partnership formation, brokering and negotiation.

  6. Web-Based Computing Resource Agent Publishing

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Web-based Computing Resource Publishing is a efficient way to provide additional computing capacity for users who need more computing resources than that they themselves could afford by making use of idle computing resources in the Web.Extensibility and reliability are crucial for agent publishing. The parent-child agent framework and primary-slave agent framework were proposed respectively and discussed in detail.

  7. Modeling culture in intelligent virtual agents

    OpenAIRE

    Mascarenhas, S.; Degens, N.; Paiva, A; Prada, R.; Hofstede, G.J.; Beulens, A.J.M.; Aylett, R.

    2015-01-01

    This work addresses the challenge of creating virtual agents that are able to portray culturally appropriate behavior when interacting with other agents or humans. Because culture influences how people perceive their social reality it is important to have agent models that explicitly consider social elements, such as existing relational factors. We addressed this necessity by integrating culture into a novel model for simulating human social behavior. With this model, we operationalized a par...

  8. Intelligent Agents in E-Commerce

    OpenAIRE

    Valentin LITOIU; Amelia BADICA; Cristian ETEGAN

    2006-01-01

    This paper emphasizes the importance of intelligent agents in e-commerce, with a particular focus on the B2C and B2B context. From the consumer buying behaviour perspective, agents can be used to assist the following stages: need identification, product brokering, buyer coalition formation, merchant brokering and negotiation. Related to B2B commerce, intelligent agents are involved in partnership formation, brokering and negotiation.

  9. Applying Software Engineering to Agent Development

    OpenAIRE

    Cohen, Mark A.; Lock Haven University; RITTER, Frank E.; Haynes, Steven R

    2010-01-01

    Developing intelligent agents and cognitive models is a complex software engineering activity. This article shows how all intelligent agent creation tools can be improved by taking advantage of established software engineering principles such as high-level languages, maintenance-oriented development environments, and software reuse. We describe how these principles have been realized in the Herbal integrated development environment, a collection of tools that allows agent developers to exploi...

  10. Agent-based argumentation for ontology alignments

    OpenAIRE

    Laera, Loredana; Tamma, Valentina; Bench-Capon, Trevor; Euzenat, Jérôme

    2006-01-01

    laera2006a International audience When agents communicate they do not necessarily use the same vocabulary or ontology. For them to interact successfully they must find correspondences between the terms used in their ontologies. While many proposals for matching two agent ontologies have been presented in the literature, the resulting alignment may not be satisfactory to both agents and can become the object of further negotiation between them. This paper describes our work constructing ...

  11. Decentralized network management based on mobile agent

    Institute of Scientific and Technical Information of China (English)

    李锋; 冯珊

    2004-01-01

    The mobile agent technology can be employed effectively for the decentralized management of complex networks. We show how the integration of mobile agent with legacy management protocol, such as simple network management protocol (SNMP), leads to decentralized management architecture. HostWatcher is a framework that allows mobile agents to roam network, collect and process data, and perform certain adaptive actions. A prototype system is built and a quantitative analysis underlines the benefits in respect to reducing network load.

  12. Sol–gel synthesis of nanostructured indium tin oxide with controlled morphology and porosity

    Energy Technology Data Exchange (ETDEWEB)

    Kőrösi, László, E-mail: ltkorosi@gmail.com [Department of Biotechnology, Nanophage Therapy Center, Enviroinvest Corporation, Kertváros u. 2, H-7632 Pécs (Hungary); Scarpellini, Alice [Department of Nanochemistry, Istituto Italiano di Tecnologia, via Morego 30, 16163 Genova (Italy); Petrik, Péter [Institute for Technical Physics and Materials Science, Konkoly-Thege út 29-33, H-1121 Budapest (Hungary); Papp, Szilvia [Department of Biotechnology, Nanophage Therapy Center, Enviroinvest Corporation, Kertváros u. 2, H-7632 Pécs (Hungary); Dékány, Imre [MTA-SZTE Supramolecular and Nanostructured Materials Research Group, University of Szeged, Dóm tér 8, H-6720 Szeged (Hungary)

    2014-11-30

    Graphical abstract: - Highlights: • Nanocrystalline ITO thin films and powders were prepared by a sol–gel method. • The nature of the compounds used for hydrolysis plays a key role in the morphology. • Hydrolysis of In{sup 3+}/Sn{sup 4+} with EA led to a rod-like morphology. • Monodisperse spherical ITO nanoparticles were obtained on the use of AC. • ITO{sub E}A was highly porous, while ITO{sub A}C contained densely packed nanocrystals. - Abstract: Nanostructured indium tin oxide (ITO) powders and thin films differing in morphology and porosity were prepared by a sol–gel method. In{sup 3+} and Sn{sup 4+} were hydrolyzed in aqueous medium through the use of ethanolamine (EA) or sodium acetate (AC). X-ray diffraction measurements demonstrated that both EA and AC furnished indium tin hydroxide, which became nanocrystalline after aging for one day. The indium tin hydroxide samples calcined at 550 °C afforded ITO with a cubic crystal structure, but the morphology differed significantly, depending on the agent used for hydrolysis. Electron microscopy revealed the formation of round monodisperse nanoparticles when AC was used, whereas the application of EA led to rod-like ITO nanoparticles. Both types of nanoparticles were suitable for the preparation of transparent and conductive ITO thin films. The influence of the morphology and porosity on the optical properties is discussed.

  13. Biomimetic synthesis of struvite with biogenic morphology and implication for pathological biomineralization

    Science.gov (United States)

    Li, Han; Yao, Qi-Zhi; Wang, Yu-Ying; Li, Yi-Liang; Zhou, Gen-Tao

    2015-01-01

    Recent studies have found that certain urinary proteins can efficiently inhibit stone formation. These discoveries are significant for developing effective therapies for stone disease, but the inhibition mechanism of crystallization remains elusive. In the present study, polyaspartic acid (PASP) was employed as a model peptide to investigate the effect of urinary proteins on the crystallization and morphological evolution of struvite. The results demonstrate that selective adsorption/binding of PASP onto the {010} and {101} faces of struvite crystals results in arrowhead-shaped morphology, which further evolves into X-shaped and unusual tabular structures with time. Noticeably, these morphologies are reminiscent of biogenic struvite morphology. Concentration-dependent experiments show that PASP can inhibit struvite growth and the inhibitory capacity increases with increasing PASP concentration, whereas aspartic acid monomers do not show a significant effect. Considering that PASP is a structural and functional analogue of the subdomains of aspartic acid-rich proteins, our results reveal that aspartic acid-rich proteins play a key role in regulating biogenic struvite morphology, and aspartic acid residues contribute to the inhibitory capacity of urinary proteins. The potential implications of PASP for developing therapeutic agents for urinary stone disease is also discussed.

  14. Agent fabrication and its implementation for agent-based electronic commerce

    OpenAIRE

    Guan, Su; Zhu, F.

    2002-01-01

    In the last decade, agent-based e-commerce has emerged as a potential role for the next generation of e-commerce. How to create agents for e-commerce applications has become a serious consideration in this field. This paper proposes a new scheme named agent fabrication and elaborates its implementation in multi-agent systems based on the SAFER (Secure Agent Fabrication, Evolution & Roaming) architecture. First, a conceptual structure is proposed for software agents carrying out e-commerce act...

  15. Effect of radioprotective agents on X-ray cataracts

    International Nuclear Information System (INIS)

    The effect of some protective agents on cataract development is briefly reviewed and new evidence is presented on the efficacy of a phosphorothioate compound (Amifostine) in inhibiting the development of X-ray-induced cataract. Morphological studies showed that at the end of 4 months, lenses from X-irradiated rats which had not received any drugs showed liquefaction in the equatorial region and at the posterior pole, as well as a marked swelling of the fibers in the anterior cortex. Animals which received 1.16g/kg of WR77913 showed considerable protection against the development of radiation induced cataracts with morphological changes in the lens being less severe than in animals receiving no drugs. When animals were treated with 0.5g/kg of Amifostine (WR2721) the lenses showed much greater protection against cataract development than with WR77913. Amifostine appears to be more effective than WR77913 in inhibiting X-ray-induced cataract development. 20 refs

  16. Effect of radioprotective agents on X-ray cataracts

    Energy Technology Data Exchange (ETDEWEB)

    Reddy, V.N.; Ikebe, H.; Giblin, F.J.; Clark, J.I.; Livesey, J.C. (Oakland Univ., Rochester, MI (USA))

    1989-01-01

    The effect of some protective agents on cataract development is briefly reviewed and new evidence is presented on the efficacy of a phosphorothioate compound (Amifostine) in inhibiting the development of X-ray-induced cataract. Morphological studies showed that at the end of 4 months, lenses from X-irradiated rats which had not received any drugs showed liquefaction in the equatorial region and at the posterior pole, as well as a marked swelling of the fibers in the anterior cortex. Animals which received 1.16g/kg of WR77913 showed considerable protection against the development of radiation induced cataracts with morphological changes in the lens being less severe than in animals receiving no drugs. When animals were treated with 0.5g/kg of Amifostine (WR2721) the lenses showed much greater protection against cataract development than with WR77913. Amifostine appears to be more effective than WR77913 in inhibiting X-ray-induced cataract development. 20 refs.

  17. Glaucoma: role of neuroprotective agents

    Directory of Open Access Journals (Sweden)

    Achyut N. Pandey

    2014-10-01

    Full Text Available Glaucoma is an optic neuropathy, considered as the second leading cause of blindness worldwide. Glaucoma is characterized by selective death of retinal ganglion cells (RGC and a progressive loss of vision. Elevated intraocular pressure (IOP is one of the most important risk factors for developing glaucoma and hence we mainly focus on lowering IOP to arrest the progression of glaucoma. However, many patients continue to demonstrate a clinically downhill course despite the control of initially raised IOP. In fact, some patients develop what is called normal tension glaucoma, not associated to an increased IOP. This emphasizes that several pressure-independent mechanisms are responsible for the development and progression of glaucomatous neuropathy and that high IOP and vascular insufficiency in the optic nerve head are only risk factors for the development of glaucoma, and are not the only target for the treatment of glaucoma. The reason is that the process of RGC death is thought to be biphasic, and the primary injury is followed by a slower secondary degeneration related to a noxious environment surrounding the apoptotic cells. This environment is characterized by changes in the extra-cellular ionic concentrations, increased amounts of free radicals, neurotrophins (NT depletion and increased glutamate-induced excitotoxicity due to high extra-cellular glutamate levels, which binds to N-methyl-D-aspartate (NMDA receptors leading to an abnormally high intracellular Ca2+ concentration. Neuroprotection is a process that attempts to preserve the remaining cells that are still vulnerable to damage, and the main aim of neuroprotective therapy is to employ pharmacologic or other means to attenuate the hostility of the environment surrounding the degenerating cells, or to supply the cells with the tools to deal with this aggression, providing resilience to the insult. Several agents have been reported neuroprotective in glaucoma, both in clinical assays

  18. Multi-agent systems simulation and applications

    CERN Document Server

    Uhrmacher, Adelinde M

    2009-01-01

    Methodological Guidelines for Modeling and Developing MAS-Based SimulationsThe intersection of agents, modeling, simulation, and application domains has been the subject of active research for over two decades. Although agents and simulation have been used effectively in a variety of application domains, much of the supporting research remains scattered in the literature, too often leaving scientists to develop multi-agent system (MAS) models and simulations from scratch. Multi-Agent Systems: Simulation and Applications provides an overdue review of the wide ranging facets of MAS simulation, i

  19. TEST SUITE GENERATION PROCESS FOR AGENT TESTING

    Directory of Open Access Journals (Sweden)

    HOUHAMDI ZINA

    2011-04-01

    Full Text Available Software agents are a promising technology for today's complex, distributed systems. Methodologies and techniques that address testing and reliability of multi agent systems are increasingly demanded, in particular to support automated test case generation and execution. In this paper, we introduce a novel approach for goal-oriented software agent testing. It specifies a testing process that complements the goal oriented methodology Tropos and reinforces the mutual relationship between goal analysis and testing. Furthermore, it defines a structured and comprehensive agent test suite generation process by providing a systematic way of deriving test cases from goal analysis.

  20. Integrating Interaction Framework for Agent Negotiation

    Institute of Scientific and Technical Information of China (English)

    肖正光; 王振杰; 徐良贤

    2003-01-01

    Agent negotiation has become increasingly important since the advent of electronic commerce.There are two kinds of interactions in the process of agent negotiation.One is the interaction between different agents,and the other is the interaction between the agent and the human user.In this paper,firstly,we introduce Q language,a scenario description language for designing interactions between agents and human users.Then we propose an integrating interaction framework for agent negotiation,in which both kinds of interactions are described by Q scenario.Our framework can make the interaction process open and easy to be understood by the users.Users can understand how the negotiation process goes and what is happening in the system including some erroneous or inappropriate actions caused by the negotiation agent.This gives the users a chance to terminate or change the behavior of negotiation agent in time to avoid unfavorable negotiation outcome.In addition,users can customize the agent's behaviors through visible interactions with it.

  1. Agent architecture for intelligent manufacturing systems

    Directory of Open Access Journals (Sweden)

    J. Madejski

    2008-08-01

    Full Text Available Purpose: Analysis is made of requirements posed by tasks of agents operating in the intelligent manufacturing systems and their resulting architecture is presented.Design/methodology/approach: Architecture of agent systems for industrial environment is presented, making it possible to generate the particular agents customised for the specific tasks, based on the automatic analysis of its required features.Findings: Extension of cellular automata approach underlying the conventional agent behaviour specification using the Fuzzy Cognitive Maps is presented in conjunction with the neural networks providing learning capability of the agents designed for the various levels of the manufacturing supervisory and execution systems. Adding reaction time specification to FCM makes it possible to analyse and design systems with the required behaviour.Research limitations/implications: Specific features of the designed agent architecture have been tested as separate mechanisms which can be merged into the final comprehensive at a later stage.Originality/value: Agent architecture is proposed for the industrial applications of single agents and their groups that can collaborate to achieve the individual and joint goals specified in reaction to changing environment conditions and into their agendas in XML format. Automatic generation of custom agent reactions models can be carried out based on a set of requirements that may be specified in the if-then rules form.

  2. Agent-Based Health Monitoring System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose combination of software intelligent agents to achieve decentralized reasoning, with fault detection and diagnosis using PCA, neural nets, and maximum...

  3. Decidability Classes for Mobile Agents Computing

    CERN Document Server

    Fraigniaud, Pierre

    2010-01-01

    We establish a classification of decision problems that are to be solved by mobile agents operating in unlabeled graphs, using a deterministic protocol. The classification is with respect to the ability of a team of agents to solve the problem, possibly with the aid of additional information. In particular, our focus is on studying differences between the decidability of a decision problem by agents and its verifiability when a certificate for a positive answer is provided to the agents. We show that the class MAV of mobile agents verifiable problems is much wider than the class MAD of mobile agents decidable problems. Our main result shows that there exist natural MAV-complete problems: the most difficult problems in this class, to which all problems in MAV are reducible. Our construction of a MAV-complete problem involves two main ingredients in mobile agents computability: the topology of the quotient graph and the number of operating agents. Beyond the class MAV we show that, for a single agent, three nat...

  4. Effect of peroxide and chain extender on mechanical properties and morphology of poly (butylene succinate)/poly (lactic acid) blends

    Science.gov (United States)

    Cherykhunthod, W.; Seadan, M.; Suttiruengwong, S.

    2015-07-01

    Poly (butylene succinate) (PBS) and poly (lactic acid) (PLA) are biodegradable polymers with high potential to replace commodity fossil-based polymers in a wide range of applications. However, these two polymers are immiscible in most ratios, but partially miscible when one of the two is a major phase. In this study, a one-step process in a twin-screw extruder was used to prepare the blends between poly (butylene succinate) (PBS) as a matrix and poly (lactic acid) (PLA) as a dispersed phase. To improve mechanical properties and morphology of blends, two reactive agents, peroxide (Perkadox) and multifunctional epoxide chain extender (Joncryl) were selected and compared. All samples were characterized for melt flow index (MFI), morphology, tensile, and impact properties. The results showed that the mechanical properties and morphology of PBS/PLA blends were improved when using both reactive agents. It was demonstrated that the increased mechanical properties resulted from good interfacial adhesion between PBS and finely dispersed PLA particles. The addition of 0.075 phr Perkadox to PBS/PLA (75:25 and 80:20) blends increased elongation at break by 7.2% and 38.4%, respectively compared with the blends without reactive agents. The results from gel content also revealed the graft copolymer existed at the interface when reactive agents were added. In the case of using multifunctional epoxide chain extender, the impact strength of the blends increased.

  5. Application Framework with Abstractions for Protocol and Agent Role

    DEFF Research Database (Denmark)

    Kristensen, Bent Bruun

    2016-01-01

    In multi-agent systems, agents interact by sending and receiving messages and the actual sequences of message form interaction structures between agents. Protocols and agents organized internally by agent roles support these interaction structures. Description and use of protocols based on agent...

  6. Auroral Morphologies of Jupiter and Saturn

    OpenAIRE

    Grodent, Denis

    2015-01-01

    We review the principal differences and similarities of the morphologies of Jupiter and Saturn's auroral emissions. We then show some examples of UV images that are expected to be acquired with Cassini UVIS at Saturn and Juno UVS at Jupiter.

  7. Morphological diagnosis of sudden cardiac death

    DEFF Research Database (Denmark)

    Hougen, H P; Valenzuela, Antonio Jesus Sanchez; Villanueva, E;

    1989-01-01

    The study reveals preliminary results of a bilateral project involving the Institute of Forensic Medicine, University of Copenhagen (Denmark) and the Institute of Legal Medicine, University of Granada (Spain). Morphological findings were compared to the results of thanatochemical analyses...

  8. Morphological representation in an endangered, polysynthetic language.

    Science.gov (United States)

    Rice, Sally; Libben, Gary; Derwing, Bruce

    2002-01-01

    This article presents the results from an initial psycholinguistic study of patterns of morphological representation in Dene Suliné (Chipewyan), an indigenous and highly endangered language spoken in Northwestern Canada. Our investigation focused on how morphological knowledge in this polysynthetic language is affected across various levels of language attrition by employing a morphological segmentation task and an off-line lexical decision task. We discuss the manner in which these tasks target different aspects of morphological ability and then turn to methodological issues associated with conducting psycholinguistic studies with language users that differ in levels of age, education, literacy, and bilingualism (Dene- English). Finally, we report on the challenges of doing psycholinguistic research outside the confines of a university setting and make some recommendations to other researchers who might wish to undertake similar studies. PMID:12081415

  9. Pollen morphology of the genus Malus Mill.

    Directory of Open Access Journals (Sweden)

    Irina Dyakova

    2014-04-01

    Full Text Available The study of pollen morphology of some species of the genus Malus (Rosaceae was carried out. All investigated species are characterized by tricolpate pollen grains, but differ by their size and coloration.

  10. Licopeno como agente antioxidante Lycopene as an antioxidant agent

    Directory of Open Access Journals (Sweden)

    Najua Juma Ismail Esh Shami

    2004-06-01

    Full Text Available Este trabalho constitui uma revisão de dados científicos sobre o consumo de licopeno e sua ação como fator antioxidante. O licopeno é considerado o carotenóide que possui a maior capacidade seqüestrante do oxigênio singlete. Radicais livres agem continuamente no organismo, podendo desencadear danos celulares e serem os responsáveis pelo desenvolvimento de câncer e certas doenças crônicas. Estudos mostram que o licopeno protege moléculas de lipídios, lipoproteínas de baixa densidade, proteínas e DNA contra o ataque dos radicais, tendo um papel essencial na proteção de doenças. Como prevenção, preconiza-se o consumo de dietas ricas em alimentos fontes de licopeno: tomates e seus produtos (purê, pasta, catchup, mamão, pitanga e goiaba; que aportem cerca de 35mg de licopeno ao dia.This paper is a review of scientific data about lycopene as an antioxidant agent. Lycopene is considered the carotenoid that has the highest capacity of capturing the singlet oxygen. Free radicals are continuously acting on the organism, being capable of promoting cellular damage and development of cancer among other chronic diseases. Studies show that lycopene protects lipid molecules, low-density lipoproteins, proteins and DNA against the attack of free radicals. They have an essential function in the protection against diseases. As a precaution, one should eat foods that are a source of lycopene: tomatoes and tomato-products (purée, pasta, ketchup, papaya, pitanga and guava; to provide approximately 35mg of lycopene a day.

  11. Cutting agents for special metals

    International Nuclear Information System (INIS)

    The quantity of use of special metals has increased year after year in the Plasma Research Institute, Nagoya University, with the development of researches on plasma and nuclear fusion. Most of these special metals are hard to cut, and in order to secure the surface smoothness and dimensional accuracy, considerable efforts are required. The method of experiment is as follows: cutting agents salt water and acetone, rape-seed oil, sulfide and chloride oil and water soluble cutting oil W grade 3; metals to be cut niobium, molybdenum, tantalum, titanium and tungsten; cutting conditions cutting speed 4.7 to 90 m/min, feed 0.07 to 0.2 mm/rev, depth of cut 0.1 to 0.4 mm, tool cemented carbide bit. Chemicals such as tetrachloromethane and trichloroethane give excellent cutting performance, but the toxicity is intense and the stimulative odor exists, accordingly they are hard to use practically. Cutting was easier when the salt water added with acetone was used than the case of rape-seed oil, but salt water is corrosive. Recently, the machining of molybdenum has been often carried out, and the water soluble cutting oil was the best. It is also good for cutting stainless steel, and its lubricating property is improved by adding some additives such as sulfur, chlorine, phosphorus and molybdenum disulfide. However after cutting with it, washing is required. (Kako, I.)

  12. Departments as Agents of Change

    Science.gov (United States)

    Lagowski, J. J.

    1996-07-01

    Higher education is changing because it has no choice. And, for the most part, outside influences are dictating the processes of change. The more fortunate institutions have had a flat budget during this period, but most have been forced to deal with a declining revenue stream as well. Legislators seem bent on micromanaging state-supported institutions, even as they cut their support. Regulators demand greater institutional accountability. Students and their parents expect more service at lower prices and increased flexibility. Technological advances have dramatically affected the availability and accessibility of extant knowledge. It is no longer a question of whether institutions will change, but rather, who will control the change. Most institutions possess long-standing academic traditions, but these are placed at risk in an increasingly competitive market that holds little sympathy for such traditions and may even see them as obstacles or barriers. As a result, the change agents will undoubtedly have a profound effect on the very nature of academic institutions. From the academic point of view, it would seem prudent to attempt to manage the changes that will inevitably occur. A number of concerned observers, notably the Pew Higher Education Roundtable and the American Association for Higher Education, argue persuasively that the academic department is the logical focus for responding to the current winds of change. Using a marketing metaphor, the academic department has been likened to a "producers' cooperative" of services that consumers seek. Thus, the department should be held accountable for the quality of teaching delivered by its members, for the coherence of its major, for its contributions to the general education curriculum, and for supervising and rewarding its individual faculty members. If departments are to be held accountable, it is surely in their best interest to act in such a way that they are accountable. Expecting academic departments to be

  13. Craniofacial morphology in Turner syndrome karyotypes

    OpenAIRE

    Bajraktarova Miševska, Cvetanka; Kočova, Mirjana; Kanurkova, Lidija; Curcieva, Cuckova, Gabriela; Bajraktarova, Bona; Maneva, Marija; Valjakova, Emilija

    2015-01-01

    ABSTRACT Introduction: A complete or partial absence of an X chromosome in the karyotype of phenotypic females has an impact on craniofacial morphology. The aim of this study was to determine the characteristics of the craniofacial complex in patients with Turner syndrome (TS), and to evaluate the influence of various karyotypes on craniofacial morphology. Material and methods: The study population was comprised of 40 TS female patients, aged 9.2 to 18 years, and 40 healthy females, age...

  14. Machine Learning for Galaxy Morphology Classification

    CERN Document Server

    Gauci, Adam; Abela, John; Magro, Alessio

    2010-01-01

    In this work, decision tree learning algorithms and fuzzy inferencing systems are applied for galaxy morphology classification. In particular, the CART, the C4.5, the Random Forest and fuzzy logic algorithms are studied and reliable classifiers are developed to distinguish between spiral galaxies, elliptical galaxies or star/unknown galactic objects. Morphology information for the training and testing datasets is obtained from the Galaxy Zoo project while the corresponding photometric and spectra parameters are downloaded from the SDSS DR7 catalogue.

  15. Morphological Analysis of Cryogenic Spray Images

    OpenAIRE

    Ganu, Hrishikesh V.; Raghunandan, B. N.

    2008-01-01

    This study gives the development of a new technique for analyzing images of Cryogenic sprays, to estimate the drop-size distribution. It has a sound mathematical basis, in the form of Mathematical Morphology, and we have tried to build up a formulation for a granulometry, starting from the elementary operations of Dilation and Erosion. An axiomatic foundation for granulometry has also been discussed. We have taken an actual LN2 spray photograph for analysis, to illustrate the use of Morpholog...

  16. Morphological Errors Made By Jordanian University Students

    OpenAIRE

    Ramadan Saleh

    2015-01-01

    This study tries to identify, classify, describe and find out the causes of the morphological errors made by the fourth year university students majoring in English in Jordan. The students who participated in the study were 20 students from Al–Zaytoonah Private University of Jordan. The procedure followed was essay writing. After analyzing the errors, the study shows that (a) the students’ competence in English morphology is poor and (b) The errors are caused by some factors such as the incon...

  17. Morphological Analysis of Living Nautilus from Palau

    OpenAIRE

    TANABE, Kazushige; Tsukahara, Junzo; タナベ, カズシゲ; ツカハラ, ジュンゾウ; 棚部, 一成; 塚原, 潤三

    1995-01-01

    Morphological features of living Nautilus in Palau (Nautilus belauensis Saunders), are described on the basis of 94 live specimens captured from Mutremdiu Bay in 1988 and 1989. Except for its larger mature size, this species is closely similar in overall shell morphology and radular and jaw structure to the wide spread species N. pompilius Linnaeus in the Southwest Pacific. This fact and available genetic data suggest a possibility that N. belauensis merely represent s a geographic variant on...

  18. Self-generated morphology in lagoon reefs

    Directory of Open Access Journals (Sweden)

    David Blakeway

    2015-05-01

    Full Text Available The three-dimensional form of a coral reef develops through interactions and feedbacks between its constituent organisms and their environment. Reef morphology therefore contains a potential wealth of ecological information, accessible if the relationships between morphology and ecology can be decoded. Traditionally, reef morphology has been attributed to external controls such as substrate topography or hydrodynamic influences. Little is known about inherent reef morphology in the absence of external control. Here we use reef growth simulations, based on observations in the cellular reefs of Western Australia’s Houtman Abrolhos Islands, to show that reef morphology is fundamentally determined by the mechanical behaviour of the reef-building organisms themselves—specifically their tendency to either remain in place or to collapse. Reef-building organisms that tend to remain in place, such as massive and encrusting corals or coralline algae, produce nodular reefs, whereas those that tend to collapse, such as branching Acropora, produce cellular reefs. The purest reef growth forms arise in sheltered lagoons dominated by a single type of reef builder, as in the branching Acropora-dominated lagoons of the Abrolhos. In these situations reef morphology can be considered a phenotype of the predominant reef building organism. The capacity to infer coral type from reef morphology can potentially be used to identify and map specific coral habitat in remotely sensed images. More generally, identifying ecological mechanisms underlying other examples of self-generated reef morphology can potentially improve our understanding of present-day reef ecology, because any ecological process capable of shaping a reef will almost invariably be an important process in real time on the living reef.

  19. EFFECTS OF CATALYST MORPHOLOGY ON HYDROTREATING REACTIONS

    OpenAIRE

    TYE CHING THIAN

    2008-01-01

    Due to the new environmental regulations for fuel quality, refineries need to process cleaner fuel. This requires an improvement in performance of hydrotreating catalysts. Improvements in catalyst activity require knowledge of the relationships between catalyst morphology and activity. Molybdenum sulfide, the generally agreed catalysts that give the best performance in hydrocracking and hydrotreating was investigated for its morphology effects on hydrotreating reactions. Three types of MoS2 c...

  20. Binary blend nanoparticles with defined morphology

    OpenAIRE

    Ghazy, Omayma

    2008-01-01

    In this study polymer blends of polystyrene and poly(propylene carbonate) were prepared using the miniemulsion process as model systems for the nanoparticles consisting of semiconducting polymers for optical applications. The blends were prepared by mixing nanoparticles of pure polymers or by fabricating blend nanoparticles including both the two polymers in each particle. The development of controlled hemispherical phase separated morphology (Janus morphology) within the blend nanoparticles ...

  1. A Morphological Theory of Human Hearing

    Science.gov (United States)

    Pamieri, Paolo

    2011-11-01

    The interdisciplinary project motivating the work discussed in this paper aims at developing an integrated framework of ideas for human hearing research. The novelty of the project consists in combining the history and philosophy of sound perception in humans with psychoacoustics and mechanics of hearing. In this paper, I present a morphological theory of human hearing, which replaces the concept of tonopic representation in the cochlea which the concept of morphological representation.

  2. Leaf morphology shift linked to climate change

    OpenAIRE

    Guerin, Greg R.; Wen, Haixia; Lowe, Andrew J

    2012-01-01

    Climate change is driving adaptive shifts within species, but research on plants has been focused on phenology. Leaf morphology has demonstrated links with climate and varies within species along climate gradients. We predicted that, given within-species variation along a climate gradient, a morphological shift should have occurred over time due to climate change. We tested this prediction, taking advantage of latitudinal and altitudinal variations within the Adelaide Geosyncline region, Sout...

  3. Morphological filters for OCR: a performance comparison

    OpenAIRE

    Mennillo, Laurent; Cousty, Jean; Najman, Laurent

    2012-01-01

    In this article is compared the ability of several morphological operators to improve OCR performance when used as preprocessing filters. An experiment on binary and greyscale images using the Tesseract OCR engine and morphological filters acting in complex, graph and vertex spaces has thus been performed and results in a good overall performance of complex and area filters. MSE measures have also been performed to evaluate the denoising ability of these filters, which again shows the good pe...

  4. Tool making, hand morphology and fossil hominins

    OpenAIRE

    Marzke, Mary W.

    2013-01-01

    Was stone tool making a factor in the evolution of human hand morphology? Is it possible to find evidence in fossil hominin hands for this capability? These questions are being addressed with increasingly sophisticated studies that are testing two hypotheses; (i) that humans have unique patterns of grip and hand movement capabilities compatible with effective stone tool making and use of the tools and, if this is the case, (ii) that there exist unique patterns of morphology in human hands tha...

  5. Thermal Degradation, Mechanical Properties and Morphology of Wheat Straw Flour Filled Recycled Thermoplastic Composites

    Directory of Open Access Journals (Sweden)

    Kadir Karakus

    2008-01-01

    Full Text Available Thermal behaviors of wheat straw flour (WF filled thermoplastic compositeswere measured applying the thermogravimetric analysis and differential scanningcalorimetry. Morphology and mechanical properties were also studied using scanningelectron microscope and universal testing machine, respectively. Presence of WF inthermoplastic matrix reduced the degradation temperature of the composites. One for WFand one for thermoplastics, two main decomposition peaks were observed. Morphologicalstudy showed that addition of coupling agent improved the compatibility between WFs andthermoplastic. WFs were embedded into the thermoplastic matrix indicating improvedadhesion. However, the bonding was not perfect because some debonding can also be seenon the interface of WFs and thermoplastic matrix. In the case of mechanical properties ofWF filled recycled thermoplastic, HDPE and PP based composites provided similar tensileand flexural properties. The addition of coupling agents improved the properties ofthermoplastic composites. MAPE coupling agents performed better in HDPE while MAPPcoupling agents were superior in PP based composites. The composites produced with thecombination of 50-percent mixture of recycled HDPE and PP performed similar with theuse of both coupling agents. All produced composites provided flexural properties requiredby the ASTM standard for polyolefin-based plastic lumber decking boards.

  6. Cladogenesis and morphological diversification in passerine birds.

    Science.gov (United States)

    Ricklefs, Robert E

    2004-07-15

    Morphological diversity tends to increase within evolving lineages over time, but the relative roles of gradual evolutionary change (anagenesis) and abrupt shifts associated with speciation events (cladogenesis, or 'punctuated equilibrium') have not been resolved for most groups of organisms. However, these two modes of evolution can be distinguished by the fact that morphological variance increases in proportion to time under anagenesis, and in proportion to the logarithm of the number of species under cladogenesis. Although species and time are themselves correlated, multiple regression analysis provides a statistical framework for partitioning their relative contributions. In this study, I use multiple regressions to evaluate the effects of time and species number on morphological diversity within clades of passerine birds. The results show clearly that number of species exerts a strong influence on morphological variance independent of time, but that time has no unique effect. Thus, morphological evolution in birds seems to be associated with cladogenesis. How lineage splitting promotes morphological diversification poses an important challenge to ecologists and evolutionary biologists. PMID:15254535

  7. Transformation of Galaxy Morphology and Luminosity Classes

    CERN Document Server

    Park, Changbom; Choi, Yun-Young

    2007-01-01

    We present a unified picture on the evolution of galaxy luminosity and morphology. Galaxy morphology is found to depend critically on the local environment set up by the nearest neighbor galaxy in addition to luminosity and the large scale density. When a galaxy is located farther than the virial radius from its closest neighbor, the probability for the galaxy to have an early morphological type is an increasing function only of luminosity and the local density due to the nearest neighbor ($\\rho_1$). The tide produced by the nearest neighbor is thought to be responsible for the morphology transformation toward the early type at these separations. When the separation is less than the virial radius, i.e. when $\\rho_1 > \\rho_{\\rm virial}$, its morphology depends also on the neighbor's morphology and the large-scale background density over a few Mpc scales ($\\rho_{20}$) in addition to luminosity and $\\rho_1$. The early type probability keeps increasing as $\\rho_1$ increases if its neighbor is an early type. But t...

  8. River Morphology and River Channel Changes

    Institute of Scientific and Technical Information of China (English)

    CHANG Howard H

    2008-01-01

    River morphology has been a subject of great challenge to scientists and engineers who recognize that any effort with regard to river engineering must be based on a proper understanding of the morphological features involved and the responses to the imposed changes. In this paper,an overview of river morphology is presented from the geomorphic viewpoint. Included in the scope are the regime concept, river channel classification, thresholds in river morphology, and geomor-phic analysis of river responses. Analytical approach to river morphology based on the physical principles for the hydraulics of flow and sediment transport processes is also presented. The appli-cation of analytical river morphology is demonstrated by an example. Modeling is the modern tech-nique to determine both short-term and long-term river channel responses to any change in the en-vironment. The physical foundation of fluvial process-response must be applied in formatting a mathematical model. A brief introduction of the mathematical model FLUVIAL-12 is described.

  9. Pedagogical agent design: The impact of agent gender, ethnicity, and instructional role

    OpenAIRE

    Baylor, A. L.; Kim, Yanghee

    2004-01-01

    To investigate the role of pedagogical agent gender and ethnicity, 230 students were randomly assigned to one of twelve conditions, where agents differed by ethnicity (African-American, Caucasian), gender (male, female), and roles (expert, motivator, and mentor).

  10. Safe motion planning for mobile agents: A model of reactive planning for multiple mobile agents

    Energy Technology Data Exchange (ETDEWEB)

    Fujimura, Kikuo.

    1990-01-01

    The problem of motion planning for multiple mobile agents is studied. Each planning agent independently plans its own action based on its map which contains a limited information about the environment. In an environment where more than one mobile agent interacts, the motions of the robots are uncertain and dynamic. A model for reactive agents is described and simulation results are presented to show their behavior patterns. 18 refs., 2 figs.

  11. Core Competencies Of A Call Centre AgentCore Competencies Of A Call Centre Agent

    OpenAIRE

    Christine White; Vera Roos

    2005-01-01

    Call centre agents are becoming increasingly important in the call centre context. They act as a contact point between the customer and the company. Call centre agents should have certain competencies to perform their duties sufficiently. Identifying competencies, required to be effective agents, will ease the task of training and recruitment. Due to the interrelatedness of the call centre agent, the management of a call centre and customers, all relevant role players’ perceptions were taken ...

  12. Comparative evaluation of the effect of different bonding agents on the ultramorphology of primary tooth dentin and the resin dentin interface

    OpenAIRE

    Pallavi Vashisth; Mousumi Goswami; Mudit Mittal; Seema Chaudhary

    2012-01-01

    Aim: To analyze and compare the changes in the ultramorphology of dentin in primary teeth using different bonding agents and to study the resin/dentin interface produced by them. Materials and Methods: Occlusal surfaces of 50 extracted human deciduous teeth were grounded to expose the dentin. The teeth were divided into two groups (A) For viewing surface morphology- 18 teeth divided into four groups: (a) for viewing dentinal morphology (3 teeth), (b) Scotchbond multi-purpose (5 teeth), (...

  13. Comparative evaluation of the effect of different bonding agents on the ultramorphology of primary tooth dentin and the resin dentin interface

    OpenAIRE

    Vashisth, Pallavi; Goswami, Mousumi; Mittal, Mudit; Chaudhary, Seema

    2012-01-01

    Aim: To analyze and compare the changes in the ultramorphology of dentin in primary teeth using different bonding agents and to study the resin/dentin interface produced by them. Materials and Methods: Occlusal surfaces of 50 extracted human deciduous teeth were grounded to expose the dentin. The teeth were divided into two groups (A) For viewing surface morphology- 18 teeth divided into four groups: (a) for viewing dentinal morphology (3 teeth), (b) Scotchbond multi-purpose (5 teeth), (c) Ad...

  14. Stock market dynamics created by interacting agents

    Directory of Open Access Journals (Sweden)

    Karl-Theodor Eisele

    2006-06-01

    Full Text Available We study a stock market model, consisting in a large number of agents, going eventually to infinity, and evaluate the stock price under the influence of opinions of different agents. Next we study the behavior of prices when the market is very nervous; there appear discontinuities (phase transitions which can be interpreted as stock market crashes.

  15. Explanation in human-agent teamwork

    NARCIS (Netherlands)

    Harbers, M.; Bradshaw, J.M.; Johnson, M.; Feltovich, P.; Bosch, K. van den; Meyer, J.J.C.

    2012-01-01

    There are several applications in which humans and agents jointly perform a task. If the task involves interdependence among the team members, coordination is required to achieve good team performance. This paper discusses the role of explanation in coordination in human-agent teams. Explanations ab

  16. Assurance in Agent-Based Systems

    International Nuclear Information System (INIS)

    Our vision of the future of information systems is one that includes engineered collectives of software agents which are situated in an environment over years and which increasingly improve the performance of the overall system of which they are a part. At a minimum, the movement of agent and multi-agent technology into National Security applications, including their use in information assurance, is apparent today. The use of deliberative, autonomous agents in high-consequence/high-security applications will require a commensurate level of protection and confidence in the predictability of system-level behavior. At Sandia National Laboratories, we have defined and are addressing a research agenda that integrates the surety (safety, security, and reliability) into agent-based systems at a deep level. Surety is addressed at multiple levels: The integrity of individual agents must be protected by addressing potential failure modes and vulnerabilities to malevolent threats. Providing for the surety of the collective requires attention to communications surety issues and mechanisms for identifying and working with trusted collaborators. At the highest level, using agent-based collectives within a large-scale distributed system requires the development of principled design methods to deliver the desired emergent performance or surety characteristics. This position paper will outline the research directions underway at Sandia, will discuss relevant work being performed elsewhere, and will report progress to date toward assurance in agent-based systems

  17. Designing Negotiating Agent for Automated Negotiations

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Traditional research in automated negotiation is focused on negotiation protocol and strategy.This paper studies automated negotiation from a new point of view, proposes a novel concept, namely negotiating agent, and discusses its significance in construction of automated negotiation system, with an abstract model formally described and the architecture designed, which supports both goal-directed reasoning and reactive response. A communication model was proposed to construct interaction mechanism used by negotiating agents, in which the negotiation language used by agents is defined.The communication model and the language are defined in a way general enough to support a wide variety of market mechanisms, thus being particularly suitable for flexible applications such as electronic business. The design and expression of the negotiation ontology is also discussed. On the base of the theoretical model of negotiating agent, negotiating agent architecture and negotiating agent communication model (NACM) are explicit and formal specifications for the agents negotiating in an E-business environment; especially, NACM defines the negotiation language template shared among all agents formally and explicitly. The novelty of the communication model is twofold.

  18. PU Sizing Agent Sector Starts Reform

    Institute of Scientific and Technical Information of China (English)

    Wang Lei

    2007-01-01

    @@ Polyurethane (PU) sizing agent is a thermoplastic PU elastomer extensively used in synthetic leather, artificial deerskin and electrostatic flocking sectors. The drastic production and demand increase of synthetic leather in China in recent years has promoted rapid consumption growth of PU sizing agent.

  19. VIRAL GASTROENTERITIS AGENTS AND WATERBORNE DISEASE

    Science.gov (United States)

    The application of electron microscopic techniques in the study of human gastroenteritis led in the 1970's to the identification of new viral agents that had previously escaped detection by routine cell culture procedures. These agents have been the focus of study by researchers ...

  20. Modeling agents with a theory of mind

    NARCIS (Netherlands)

    Harbers, M.; Bosch, K. van den; Meyer, J.J.C.

    2009-01-01

    Training systems with intelligent virtual agents provide an effective means to train people for complex, dynamic tasks like crisis management or firefighting. Virtual agents provide more adequate behavior and explanations if they not only take their own goals and beliefs into account, but also the a

  1. Practice among Novice Change Agents in Schools

    Science.gov (United States)

    Blossing, Ulf

    2016-01-01

    The aim of the article is to understand practice as negotiation of meaning among novice and internal change agents in school organisations. The research question is as follows: What themes of participation and reification/management occur among the change agents? The study was qualitative in design using the social learning theory of community of…

  2. Computational Intelligence Agent-Oriented Modelling

    Czech Academy of Sciences Publication Activity Database

    Neruda, Roman

    2006-01-01

    Roč. 5, č. 2 (2006), s. 430-433. ISSN 1109-2777 R&D Projects: GA MŠk 1M0567 Institutional research plan: CEZ:AV0Z10300504 Keywords : multi - agent system s * adaptive agent s * computational intelligence Subject RIV: IN - Informatics, Computer Science

  3. Transient Diversity in Multi-Agent Systems

    OpenAIRE

    Lyback, David

    2003-01-01

    Diversity is an important aspect of highly efficient multi-agent teams. We introduce the main factors that drive a multi-agent system in either direction along the diversity scale. A metric for diversity is described, and we speculate on the concept of transient diversity. Finally, an experiment on social entropy using a RoboCup simulated soccer team is presented.

  4. Security of Mobile Agents on the Internet.

    Science.gov (United States)

    Corradi, Antonio; Montanari, Rebecca; Stefanelli, Cesare

    2001-01-01

    Discussion of the Internet focuses on new programming paradigms based on mobile agents. Considers the security issues associated with mobile agents and proposes a security architecture composed of a wide set of services and components capable of adapting to a variety of applications, particularly electronic commerce. (Author/LRW)

  5. Agent programming languages: programming with mental models

    NARCIS (Netherlands)

    Hindriks, K.V.

    2001-01-01

    Intelligent Agents are personal assistants which can provide proactive support to users by executing routine activities like searching on the Internet, the scheduling of meetings, etc. The concept of an Intelligent Agent has its roots in Artificial Intelligence and provides a basis for the con

  6. Ultrasound contrast agents: An overview

    Energy Technology Data Exchange (ETDEWEB)

    Cosgrove, David [Imaging Sciences Department, Imperial College, Hammersmith Hospital, London (United Kingdom)]. E-mail: d.cosgrove@csc.mrc.ac.uk

    2006-12-15

    With the introduction of microbubble contrast agents, diagnostic ultrasound has entered a new era that allows the dynamic detection of tissue flow of both the macro and microvasculature. Underpinning this development is the fact that gases are compressible, and thus the microbubbles expand and contract in the alternating pressure waves of the ultrasound beam, while tissue is almost incompressible. Special software using multiple pulse sequences separates these signals from those of tissue and displays them as an overlay or on a split screen. This can be done at low acoustic pressures (MI < 0.3) so that the microbubbles are not destroyed and scanning can continue in real time. The clinical roles of contrast enhanced ultrasound scanning are expanding rapidly. They are established in echocardiography to improve endocardial border detection and are being developed for myocardial perfusion. In radiology, the most important application is the liver, especially for focal disease. The approach parallels that of dynamic CT or MRI but ultrasound has the advantages of high spatial and temporal resolution. Thus, small lesions that can be indeterminate on CT can often be studied with ultrasound, and situations where the flow is very rapid (e.g., focal nodular hyperplasia where the first few seconds of arterial perfusion may be critical to making the diagnosis) are readily studied. Microbubbles linger in the extensive sinusoidal space of normal liver for several minutes whereas they wash out rapidly from metastases, which have a low vascular volume and thus appear as filling defects. The method has been shown to be as sensitive as three-phase CT. Microbubbles have clinical uses in many other applications where knowledge of the microcirculation is important (the macrocirculation can usually be assessed adequately using conventional Doppler though there are a few important situations where the signal boost given by microbubbles is useful, e.g., transcranial Doppler for evaluating

  7. SDSS superclusters: morphology and galaxy content

    Science.gov (United States)

    Einasto, M.; Lietzen, H.; Tempel, E.; Gramann, M.; Liivamägi, L. J.; Einasto, J.

    2014-02-01

    Context. Understanding the formation, evolution and present-day properties of the cosmic web and objects forming it is an important task in cosmology. Aims: We compare the galaxy populations in superclusters of different morphology in the nearby Universe (180 h-1 Mpc ≤ d ≤ 270 h-1 Mpc) to see whether the inner structure and overall morphology of superclusters are important in shaping galaxy properties in superclusters. Methods: We find supercluster morphology with Minkowski functionals and analyse the probability density distributions of colours, morphological types, stellar masses, star formation rate (SFR) of galaxies, and the peculiar velocities of the main galaxies in groups in superclusters of filament and spider types, and in the field. We test the statistical significance of the results with the KS test. Results: The fraction of red, early-type, low SFR galaxies in filament-type superclusters is higher than in spider-type superclusters; in low-density global environments their fraction is lower than in superclusters. In all environments the fraction of red, high stellar mass, and low SFR galaxies in rich groups is higher than in poor groups. In superclusters of spider morphology red, high SFR galaxies have higher stellar masses than in filament-type superclusters. Groups of equal richness host galaxies with larger stellar masses, a larger fraction of early-type and red galaxies, and a higher fraction of low SFR galaxies, if they are located in superclusters of filament morphology. The peculiar velocities of the main galaxies in groups from superclusters of filament morphology are higher than in those of spider morphology. Groups with higher peculiar velocities of their main galaxies in filament-type superclusters are located in higher density environment than those with low peculiar velocities. There are significant differences between galaxy populations of the individual richest superclusters. Conclusions: Both local (group) and global (supercluster

  8. Developing a New Approach for Arabic Morphological Analysis and Generation

    OpenAIRE

    Gridach, Mourad; Chenfour, Noureddine

    2011-01-01

    Arabic morphological analysis is one of the essential stages in Arabic Natural Language Processing. In this paper we present an approach for Arabic morphological analysis. This approach is based on Arabic morphological automaton (AMAUT). The proposed technique uses a morphological database realized using XMODEL language. Arabic morphology represents a special type of morphological systems because it is based on the concept of scheme to represent Arabic words. We use this concept to develop th...

  9. Your company's secret change agents.

    Science.gov (United States)

    Pascale, Richard Tanner; Sternin, Jerry

    2005-05-01

    Organizational change has traditionally come about through top-down initiatives such as hiring experts or importing best-of-breed practices. Such methods usually result in companywide rollouts of templates mandated from on high. These do little to get people excited. But within every organization, there are a few individuals who find unique ways to look at problems that seem impossible to solve. Although these change agents start out with the same tools and access to resources as their peers, they are able to see solutions where others do not. They find a way to bridge the divide between what is happening and what is possible. These positive deviants are the key, the authors believe, to a better way of creating organizational change. Your company can make the most of their methods by following six steps. In Step 1, Make the group the guru, the members of the community are engaged in the process of their own evolution. Step 2, Reframe through facts, entails restating the problem in a way that opens minds to new possibilities. Step 3, Make it safe to learn, involves creating an environment that supports innovative ideas. In Step 4, Make the problem concrete, the community combats abstraction by stating uncomfortable truths. In Step 5, Leverage social proof, the community looks to the larger society for examples of solutions that have worked in parallel situations. In Step 6, Confound the immune defense response, solutions are introduced organically from within the group in a way that promotes acceptance. Throughout the steps, the leader must suspend his or her traditional role in favor of more facilitatory practices. The positive-deviance approach has unearthed solutions to such complicated and diverse problems as malnutrition in Mali and human trafficking in East Java. This methodology can help solve even the most extreme dilemmas. PMID:15929405

  10. 9th KES Conference on Agent and Multi-Agent Systems : Technologies and Applications

    CERN Document Server

    Howlett, Robert; Jain, Lakhmi

    2015-01-01

    Agents and multi-agent systems are related to a modern software paradigm which has long been recognized as a promising technology for constructing autonomous, complex and intelligent systems. The topics covered in this volume include agent-oriented software engineering, agent co-operation, co-ordination, negotiation, organization and communication, distributed problem solving, specification of agent communication languages, agent privacy, safety and security, formalization of ontologies and conversational agents. The volume highlights new trends and challenges in agent and multi-agent research and includes 38 papers classified in the following specific topics: learning paradigms, agent-based modeling and simulation, business model innovation and disruptive technologies, anthropic-oriented computing, serious games and business intelligence, design and implementation of intelligent agents and multi-agent systems, digital economy, and advances in networked virtual enterprises. Published p...

  11. Advances on Practical Applications of Agents and Multi-Agent Systems 10th International Conference on Practical Applications of Agents and Multi-Agent Systems

    CERN Document Server

    Müller, Jörg; Rodríguez, Juan; Pérez, Javier

    2012-01-01

    Research on Agents and Multi-Agent Systems has matured during the last decade and many effective applications of this technology are now deployed. PAAMS provides an international forum to present and discuss the latest scientific developments and their effective applications, to assess the impact of the approach, and to facilitate technology transfer. PAAMS started as a local initiative, but has since grown to become THE international yearly platform to present, to discuss, and to disseminate the latest developments and the most important outcomes related to real-world applications. It provides a unique opportunity to bring multi-disciplinary experts, academics and practitioners together to exchange their experience in the development and deployment of Agents and Multi-Agent Systems. PAAMS intends to bring together researchers and developers from industry and the academic world to report on the latest scientific and technical advances on the application of multi-agent systems, to discuss and debate the major ...

  12. Highlights on Practical Applications of Agents and Multi-Agent Systems 10th International Conference on Practical Applications of Agents and Multi-Agent Systems

    CERN Document Server

    Sánchez, Miguel; Mathieu, Philippe; Rodríguez, Juan; Adam, Emmanuel; Ortega, Alfonso; Moreno, María; Navarro, Elena; Hirsch, Benjamin; Lopes-Cardoso, Henrique; Julián, Vicente

    2012-01-01

    Research on Agents and Multi-Agent Systems has matured during the last decade and many effective applications of this technology are now deployed. PAAMS provides an international forum to present and discuss the latest scientific developments and their effective applications, to assess the impact of the approach, and to facilitate technology transfer. PAAMS started as a local initiative, but has since grown to become THE international yearly platform to present, to discuss, and to disseminate the latest developments and the most important outcomes related to real-world applications. It provides a unique opportunity to bring multi-disciplinary experts, academics and practitioners together to exchange their experience in the development and deployment of Agents and Multi-Agent Systems. PAAMS intends to bring together researchers and developers from industry and the academic world to report on the latest scientific and technical advances on the application of multi-agent systems, to discuss and debate the major ...

  13. Security Issues in Mobile Agent Paradigm

    Directory of Open Access Journals (Sweden)

    Nitin Jain

    2011-05-01

    Full Text Available A mobile Agent is a Software program that migrates from node tonode of a heterogeneous network. They are goal-oriented i.e. workautonomously towards a goal, capable of suspending their executionon one platform and moving to other where they can resumeexecution using resources of these nodes and they meet and interactwith other agents. Agents may be stationary, always resident at asingle platform or mobile, capable of moving among differentplatforms at different time. The mobile agent paradigm providesmany benefits in developments of distributed application at the sametime introduce new requirements for security issues with thesesystems. In this paper we try to focus mainly on security issues thatarise when mobile agent paradigm comes into play.

  14. Fault Reconnaissance Agent for Sensor Networks

    Directory of Open Access Journals (Sweden)

    Elhadi M. Shakshuki

    2010-01-01

    Full Text Available One of the key prerequisite for a scalable, effective and efficient sensor network is the utilization of low-cost, low-overhead and high-resilient fault-inference techniques. To this end, we propose an intelligent agent system with a problem solving capability to address the issue of fault inference in sensor network environments. The intelligent agent system is designed and implemented at base-station side. The core of the agent system – problem solver – implements a fault-detection inference engine which harnesses Expectation Maximization (EM algorithm to estimate fault probabilities of sensor nodes. To validate the correctness and effectiveness of the intelligent agent system, a set of experiments in a wireless sensor testbed are conducted. The experimental results show that our intelligent agent system is able to precisely estimate the fault probability of sensor nodes.

  15. Development of Soda Residue Concrete Expansion Agent

    Institute of Scientific and Technical Information of China (English)

    WANG Bao-min; WANG Li-jiu; M F Mohd Zain; F C Lai

    2003-01-01

    A new type of concrete expansion agent has been successfully developed for the first time in the world by utilizing an industrial waste residue-soda residue and an industrial wasteliquor.Adding 3%-6% of the agent into Portland cement enables a shrinkage-compensating concrete to be prepared.Mortar and concrete containing this expansion agent have better shrinkage-compensating and mechanical properties.The raw materials component,production process,technical properties,micro-analysis of mortar made with this expansion agent,mechanism of expansion and research results are described in this article.The experimental results show that the new type of concrete expansion agent accords with the standard and its main mineral component is xCaO-ySO3-zAl2O3.

  16. A Network Management Framework Using Mobile Agents

    Directory of Open Access Journals (Sweden)

    Jonathan Lefebvre

    2006-01-01

    Full Text Available Network management of heterogeneous networks is still hard to achieve automatically and efficiently. In this study, we present a framework that has the ability to perform network management tasks on heterogeneous networks using mobile agents. This framework handles the inability of many network devices to run mobile agents. While the main focus of the project is the framework, we present an example of mobile agents that are able to locate a fixed set of network failures and detect the possible causes accurately. Experimental results show that some network management tasks can be more easily executed by mobile agents. In particular, search and diagnostic mobile agents are able to find more precisely a cause of a network failure by finding alternate paths to gather more data about the failure.

  17. Econophysics of agent-based models

    CERN Document Server

    Aoyama, Hideaki; Chakrabarti, Bikas; Chakraborti, Anirban; Ghosh, Asim

    2014-01-01

    The primary goal of this book is to present the research findings and conclusions of physicists, economists, mathematicians and financial engineers working in the field of "Econophysics" who have undertaken agent-based modelling, comparison with empirical studies and related investigations. Most standard economic models assume the existence of the representative agent, who is “perfectly rational” and applies the utility maximization principle when taking action. One reason for this is the desire to keep models mathematically tractable: no tools are available to economists for solving non-linear models of heterogeneous adaptive agents without explicit optimization. In contrast, multi-agent models, which originated from statistical physics considerations, allow us to go beyond the prototype theories of traditional economics involving the representative agent. This book is based on the Econophys-Kolkata VII Workshop, at which many such modelling efforts were presented. In the book, leading researchers in the...

  18. CEST and PARACEST MR contrast agents

    International Nuclear Information System (INIS)

    In this review we describe the status of development for a new class of magnetic resonance (MR) contrast agents, based on chemical exchange saturation transfer (CEST). The mathematics and physics relevant to the description of the CEST effect in MR are presented in an appendix published in the online version only. We discuss the issues arising when translating in vitro results obtained with CEST agents to using these MR agents in in vivo model studies and in humans. Examples are given on how these agents are imaged in vivo. We summarize the status of development of these CEST agents, and speculate about the next steps that may be taken towards the demonstration of CEST MR imaging in clinical applications

  19. Incorporating Inertia Into Multi-Agent Systems

    CERN Document Server

    Man, W C

    2005-01-01

    We consider a model that demonstrates the crucial role of inertia and stickiness in multi-agent systems, based on the Minority Game (MG). The inertia of an agent is introduced into the game model by allowing agents to apply hypothesis testing when choosing their best strategies, thereby reducing their reactivity towards changes in the environment. From massive numerical simulations, a remarkable improvement of global cooperation is observed throughout the whole phase space, and the maladaptation behaviour due to over-reaction of agents is removed. Also, these agents are found to be advantageous over the standard ones, which are sometimes too sensitive to attain a fair success rate. Analytical calculation on determining the minimum amount of inertia needed to achieve the above improvement is also provided, which is consistent with the numerical data.

  20. Ecology Based Decentralized Agent Management System

    Science.gov (United States)

    Peysakhov, Maxim D.; Cicirello, Vincent A.; Regli, William C.

    2004-01-01

    The problem of maintaining a desired number of mobile agents on a network is not trivial, especially if we want a completely decentralized solution. Decentralized control makes a system more r e bust and less susceptible to partial failures. The problem is exacerbated on wireless ad hoc networks where host mobility can result in significant changes in the network size and topology. In this paper we propose an ecology-inspired approach to the management of the number of agents. The approach associates agents with living organisms and tasks with food. Agents procreate or die based on the abundance of uncompleted tasks (food). We performed a series of experiments investigating properties of such systems and analyzed their stability under various conditions. We concluded that the ecology based metaphor can be successfully applied to the management of agent populations on wireless ad hoc networks.